Transient receptor potential cation channel subfamily M member-like 2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30003521 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Human
Match: TRPM2 (transient receptor potential cation channel subfamily M member 2 [Source:HGNC Symbol;Acc:HGNC:12339]) HSP 1 Score: 297.745 bits (761), Expect = 4.419e-82 Identity = 295/1116 (26.43%), Postives = 506/1116 (45.34%), Query Frame = 3
Query: 132 NGFEDQIQEFINKKFNTRTCYKYKEKSK------DICHCNRHLNHHTNKSNSPE-----EWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENT-SEDEKGKVI-LDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQA---DGFLVQI-----LFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGA-------DKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEV--IQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKK----SNSTEQNRLFDAGDIIAKLSGNLL---------NNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWST-QDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIII-TIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF-DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGEL------MLENFDVAGPCNGTD-----CIVSSGT----------VLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
N ++ + +I + + C + E SK +C C H ++ P +W + FG I F+G + K++R D +Y LMT +W + P ++IS+ GG KN ++ K F++GL+ V + W+I G G+ K V EA+ +F + ++ IGV+TWGTV + L I F E ED +G + LD+ + F+ DDGT QY E+ + E F+ +Q G ++I + EGG L A + P VV++GSGRVA++I++V LP + +I I + + Q ++ + E+T + ++ + V + D D ILQA++ + ++ LKL + +N +IA +F DE + + +L NKPEFV LF+EN + FV L LYE + D C H + + + + + + ++ ++ +L G+ N++ L P ++ + S LY+ F+ +DL +WA++ R +L+ I+W S++ I +AL + ILK+++ + L +++Y+ A + T+ Y K + + LL R W TCLQ+A+ ++F++H +++ TKVW G LS W++ + + F L L L+ +F K L D T F+ AP+V F +++LSY FL +FAY +V+ +P+ W E IY+++ + EE+RQ+F D + G K YF WNK D I++F+A + R IP + R + S+ +F +R M + ++K++GPKII+++ M++D+ FFL + ++V+++G+ +++ N LF+ VY + FG++ + N + P NGTD C S T ++ ++LL TN+LL+NLLIAMF YTF Q+QE ++++W F R L++E++G+P PPP + H
Sbjct: 53 NDKQESLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEATKPHTFQGTQWDPKKHVQEMPTDAFGDIVFTGL----SQKVKKYVRVSQ----DTPSSVIYHLMTQ--HWGLDVPNLLISVTGGAKNF-NMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELITIGVATWGTVHRREGL-------IHPTGSFPAEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIDNATTNGTPCVVVEGSGRVADVIAQVANLPVSDI--TISLIQQKLSVFFQEMFETFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIF----MDEWQWKPSDLHPTMTAALISNKPEFVKLFLENGVQLKEFVTWDTLLYLYE-NLDPS--------CLFHSKLQKVLVEDPERPACAPAAPRLQMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQGVSLRS---LYKRSSGHVTFTMDPIRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKEEEDTDSSEEMLAL---AEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLI-------------------SFREKRLQDVG-----------TPAARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVPS-------WCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRL-IPATLYP-GRVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFGQIPGYIDGVNFNPEHCSP-NGTDPYKPKCPESDATQQRPAFPEWLTVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPPPFILLSH 1089
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Human
Match: TRPM2 (transient receptor potential cation channel subfamily M member 2 [Source:HGNC Symbol;Acc:HGNC:12339]) HSP 1 Score: 297.36 bits (760), Expect = 5.905e-82 Identity = 295/1116 (26.43%), Postives = 506/1116 (45.34%), Query Frame = 3
Query: 132 NGFEDQIQEFINKKFNTRTCYKYKEKSK------DICHCNRHLNHHTNKSNSPE-----EWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENT-SEDEKGKVI-LDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQA---DGFLVQI-----LFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGA-------DKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEV--IQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKK----SNSTEQNRLFDAGDIIAKLSGNLL---------NNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWST-QDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIII-TIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF-DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGEL------MLENFDVAGPCNGTD-----CIVSSGT----------VLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
N ++ + +I + + C + E SK +C C H ++ P +W + FG I F+G + K++R D +Y LMT +W + P ++IS+ GG KN ++ K F++GL+ V + W+I G G+ K V EA+ +F + ++ IGV+TWGTV + L I F E ED +G + LD+ + F+ DDGT QY E+ + E F+ +Q G ++I + EGG L A + P VV++GSGRVA++I++V LP + +I I + + Q ++ + E+T + ++ + V + D D ILQA++ + ++ LKL + +N +IA +F DE + + +L NKPEFV LF+EN + FV L LYE + D C H + + + + + + ++ ++ +L G+ N++ L P ++ + S LY+ F+ +DL +WA++ R +L+ I+W S++ I +AL + ILK+++ + L +++Y+ A + T+ Y K + + LL R W TCLQ+A+ ++F++H +++ TKVW G LS W++ + + F L L L+ +F K L D T F+ AP+V F +++LSY FL +FAY +V+ +P+ W E IY+++ + EE+RQ+F D + G K YF WNK D I++F+A + R IP + R + S+ +F +R M + ++K++GPKII+++ M++D+ FFL + ++V+++G+ +++ N LF+ VY + FG++ + N + P NGTD C S T ++ ++LL TN+LL+NLLIAMF YTF Q+QE ++++W F R L++E++G+P PPP + H
Sbjct: 53 NDKQESLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEATKPHTFQGTQWDPKKHVQEMPTDAFGDIVFTGL----SQKVKKYVRVSQ----DTPSSVIYHLMTQ--HWGLDVPNLLISVTGGAKNF-NMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELITIGVATWGTVHRREGL-------IHPTGSFPAEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIDNATTNGTPCVVVEGSGRVADVIAQVANLPVSDI--TISLIQQKLSVFFQEMFETFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIF----MDEWQWKPSDLHPTMTAALISNKPEFVKLFLENGVQLKEFVTWDTLLYLYE-NLDPS--------CLFHSKLQKVLVEDPERPACAPAAPRLQMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQGVSLRS---LYKRSSGHVTFTMDPIRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKEEEDTDSSEEMLAL---AEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLI-------------------SFREKRLQDVG-----------TPAARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVPS-------WCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRL-IPATLYP-GRVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFGQIPGYIDGVNFNPEHCSP-NGTDPYKPKCPESDATQQRPAFPEWLTVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPPPFILLSH 1089
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Human
Match: TRPM2 (transient receptor potential cation channel subfamily M member 2 [Source:HGNC Symbol;Acc:HGNC:12339]) HSP 1 Score: 297.36 bits (760), Expect = 5.905e-82 Identity = 295/1116 (26.43%), Postives = 506/1116 (45.34%), Query Frame = 3
Query: 132 NGFEDQIQEFINKKFNTRTCYKYKEKSK------DICHCNRHLNHHTNKSNSPE-----EWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENT-SEDEKGKVI-LDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQA---DGFLVQI-----LFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGA-------DKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEV--IQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKK----SNSTEQNRLFDAGDIIAKLSGNLL---------NNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWST-QDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIII-TIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF-DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGEL------MLENFDVAGPCNGTD-----CIVSSGT----------VLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
N ++ + +I + + C + E SK +C C H ++ P +W + FG I F+G + K++R D +Y LMT +W + P ++IS+ GG KN ++ K F++GL+ V + W+I G G+ K V EA+ +F + ++ IGV+TWGTV + L I F E ED +G + LD+ + F+ DDGT QY E+ + E F+ +Q G ++I + EGG L A + P VV++GSGRVA++I++V LP + +I I + + Q ++ + E+T + ++ + V + D D ILQA++ + ++ LKL + +N +IA +F DE + + +L NKPEFV LF+EN + FV L LYE + D C H + + + + + + ++ ++ +L G+ N++ L P ++ + S LY+ F+ +DL +WA++ R +L+ I+W S++ I +AL + ILK+++ + L +++Y+ A + T+ Y K + + LL R W TCLQ+A+ ++F++H +++ TKVW G LS W++ + + F L L L+ +F K L D T F+ AP+V F +++LSY FL +FAY +V+ +P+ W E IY+++ + EE+RQ+F D + G K YF WNK D I++F+A + R IP + R + S+ +F +R M + ++K++GPKII+++ M++D+ FFL + ++V+++G+ +++ N LF+ VY + FG++ + N + P NGTD C S T ++ ++LL TN+LL+NLLIAMF YTF Q+QE ++++W F R L++E++G+P PPP + H
Sbjct: 53 NDKQESLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEATKPHTFQGTQWDPKKHVQEMPTDAFGDIVFTGL----SQKVKKYVRVSQ----DTPSSVIYHLMTQ--HWGLDVPNLLISVTGGAKNF-NMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELITIGVATWGTVHRREGL-------IHPTGSFPAEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIDNATTNGTPCVVVEGSGRVADVIAQVANLPVSDI--TISLIQQKLSVFFQEMFETFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIF----MDEWQWKPSDLHPTMTAALISNKPEFVKLFLENGVQLKEFVTWDTLLYLYE-NLDPS--------CLFHSKLQKVLVEDPERPACAPAAPRLQMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQGVSLRS---LYKRSSGHVTFTMDPIRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKEEEDTDSSEEMLAL---AEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLI-------------------SFREKRLQDVG-----------TPAARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVPS-------WCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRL-IPATLYP-GRVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFGQIPGYIDGVNFNPEHCSP-NGTDPYKPKCPESDATQQRPAFPEWLTVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPPPFILLSH 1089
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Human
Match: TRPM3 (transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992]) HSP 1 Score: 279.641 bits (714), Expect = 1.613e-76 Identity = 303/1209 (25.06%), Postives = 538/1209 (44.50%), Query Frame = 3
Query: 153 QEFINKKFNTRTCYKYKEKSKDI--CHCNRHLNHHTNKSNS-------------------PEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIR--FDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQ------ADGF-LVQILFEGGRRALLNAYKAIKDK--VPLVVIKGSGRVANMI------SEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMM--DANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNR--LFDAGDIIAKLSGNLLNNQYSQ---------LF---------------DKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMA------DLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPT-WKIIITIPFSLFLMKLMIMPSFPRKGKNPKDVP---DAKNFH-----------------------NKHLLDENAKAPPLKSEE--------ITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTD------------CIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIIS-LPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFEQFCLNE 3419
+ +I + F R C +KD C C R + H + S E+WS S +T L FG I+F G H + ++R FD + D + LMT W + P ++IS++GGL+N E + K+ F +GLI W+ G++ G+ + V +A+ + H + ++ IG++ WG V+N + L IG ++V Y+ S +L++++ F+ D+GT +Y EV+ + E + Q G +V ++ EGG + + ++D VP+VV GSGR ++++ SE GL +++ ++ + + ++ T + +++ M C KK+++ M + + D IL A++ GA+ S L L + +N +IA +F + +G +++ L +L ++ +FV L +EN + F+ + L+ELY ++ P + L L RD KK N R L D G +I L G Y++ LF D PL T EE + D + + F + +L +WA+L R +++ W+ + + AL A + K MA D+V +++ ++L S+ + LA ++ Q+Y + + LL L W+ TCLQ+A+ +F+ H+ + T +WMG L + K+I+ I ++ L + KN D+P A+ H L N ++ K EE I + + FY APIVKF + L+YI +LM+F Y LV++ E Q W I Y+ T IE++R++ E K + WN D + I++F ++ R Q R ++ +++ + IR + + VNK +GP ++MI M+ D+++F+ I ++ ++++G+ +++ +PN E + L K+I Y P++ +GE+ + D PC + C + V A +LL+ N+LL+NLLIA+F TF +++ S ++W F R QL+ F+ +P+ PPPL IF H I L C+ R + ++ + + + K+++FE+ C+ E
Sbjct: 62 KSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGG---HSNKAMYVRVSFDTKPDL------LLHLMTKE--WQLELPKLLISVHGGLQNFE-LQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKD---HASKSRGKICTIGIAPWGIVENQEDL-------IGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL-LVTIQKTFTY---------TRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVG--SLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELY----NTRHGP-SNTLYHLVRDV-------KKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMV-----DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL--------EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKM----ERWPSTQEWIVIS---YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQ-DQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQID--PPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEE 1201
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Human
Match: TRPM3 (transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992]) HSP 1 Score: 280.411 bits (716), Expect = 2.319e-76 Identity = 308/1226 (25.12%), Postives = 548/1226 (44.70%), Query Frame = 3
Query: 105 NTKSEITIKNGFEDQI----QEFINKKFNTRTCYKYKEKSKDI--CHCNRHLNHHTNKSNS-------------------PEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIR--FDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQ------ADGF-LVQILFEGGRRALLNAYKAIKD--KVPLVVIKGSGRVANMI------SEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMM--DANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKS---------YFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQ---------LF-----DKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMA------DLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTW-KIIITIPFSLFLMKLMIMPSFPRKGKNPKDVP---DAKNFH-----------------------NKHLLDENAKAPPLKSEE--------ITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTD------------CIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIIS-LPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFEQFCLNE 3419
++K T ++G Q + +I + F R C +KD C C R + H + S E+WS S +T L FG I+F G H + ++R FD + D + LMT W + P ++IS++GGL+N E + K+ F +GLI W+ G++ G+ + V +A+ + H + ++ IG++ WG V+N + L IG ++V Y+ S +L++++ F+ D+GT +Y EV+ + E + Q G +V ++ EGG + + ++D VP+VV GSGR ++++ SE GL +++ ++ + + ++ T + +++ M C KK+++ M + + D IL A++ GA+ S L L + +N +IA +F + +G +++ L +L ++ +FV L +EN + F+ + L+ELY ++ P + L L RD K YFK N + + L D G +I L G Y++ LF D PL T EE + D + + F + +L +WA+L R +++ W+ + + AL A + K MA D+V +++ ++L S+ + LA ++ Q+Y + + LL L W+ TCLQ+A+ +F+ H+ + T +WMG L + K+I+ I ++ L KN D+P A+ H L N ++ K EE I + + FY APIVKF + L+YI +LM+F Y LV++ E Q W I Y+ T IE++R++ E K + WN D + I++F ++ R Q R ++ +++ + IR + + VNK +GP ++MI M+ D+++F+ I ++ ++++G+ +++ +PN E + L K+I Y P++ +GE+ + D PC + C + V A +LL+ N+LL+NLLIA+F TF +++ S ++W F R QL+ F+ +P+ PPPL IF H I L C+ R + ++ + + + K+++FE+ C+ E
Sbjct: 44 SSKQGSTKRSGLPSQQTPAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGG---HSNKAMYVRVSFDTKPDL------LLHLMTKE--WQLELPKLLISVHGGLQNFE-LQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKD---HASKSRGKICTIGIAPWGIVENQEDL-------IGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL-LVTIQKTFTY---------TRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVG--SLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELY----NTRHGP-SNTLYHLVRDVKKREYPGFGWIYFKGNLPPDY--RISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMV-----DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEF--------KNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKM----ERWPSTQEWIVIS---YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQ-DQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQID--PPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEE 1205
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Celegans
Match: gtl-1 (GTL-1; Gon-Two Like (TRP subfamily) [Source:UniProtKB/TrEMBL;Acc:G5ECM4]) HSP 1 Score: 158.688 bits (400), Expect = 9.012e-39 Identity = 167/707 (23.62%), Postives = 316/707 (44.70%), Query Frame = 3
Query: 267 SPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQR-LNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFV----KKQADGFLVQILFEGGRRA--LLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPE-----EDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANM-SFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNK-------------KSNSTEQ---NRLF----------------------------DAG-DIIAKLSGNLLNNQYS---QLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLV-LIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDL 2201
+P WS ++T + +G I F G H ++ R + D R + LM W + P +II+INGGL + + + F++G++ + K W+I SGL G+ K + A+ + H K+ V IG+++WG +K R + ++ TN+ + NT E L+ + FLF D+GT +Y E+ + E ++ KK++ LV ++ EGG +++ Y ++P++V GSGR A++++ S+N L + I Q+ + ++ +VE N K + I+ + +++ D I+ ++ G + S L+L + +N ++IA +F++ E + + + +L +++ +FV+L +EN + F+ L+ LY +++K P L +L D+K + KL + KSN T++ N+ F DAG + ++ + +L+NN + LF+ +R+ +D ++F+ L E F + DL +WA+L+ R ++ ++W + + AL A+ + +A L G+ + + T+ S ++ +LA ++ + +T LL LA W TCL +A N +FL H C+ + +W G L
Sbjct: 178 TPGRWSIQSHTEIVPTDAYGNIVFEGTA-----HHAQYARISFDSDP----RDIVHLMMK--VWKLKPPKLIITINGGLTKFD-LQPKLARTFRKGIMKIAKSTDAWIITSGLDEGVVKHLDSALHDHGNHTS--KNHVVAIGIASWGMLKQRSRFVGKDSTVTYATNV---FNNTRLKE-----LNDNHSYFLFSDNGTVNRYGAEIIMRKRLEAYLAQGDKKRSAIPLVCVVLEGGAFTIKMVHDYVTTIPRIPVIVCDGSGRAADILAFAHQAVSQNG-------FLSDNIRNQLVNIVRRIFGYDPKTAQKLIKQIVECSTN-KSLMTIFRLGESSREDLDHVIMSCLLKGQNLSPPEQLQLALAWNRADIARTEIFANGT--EWTTQDLHNAMIEALSNDRIDFVHLLLENGVSMQKFLTYGRLEHLY----NTDKGPQNTLRTNLLVDSKHHIKLVEVGRLVENLMGNLYKSNYTKEEFKNQYFLFNNRKQFGKRVHSNSNGGRNDVIGPSGDAGRERMSSMQISLINNARNSIISLFNGGGRKRE--SDDEDDFSNLEEEANMDFTFRYPYSDLMIWAVLTKRQKMAKLMWTHGEEGMAKALVASRLYVSLAKTASLATGEIGMSQDFTEFSDEFSELAVEVLEYCTKHGRDQTLRLLTCELANWGDETCLSLAANNGHRKFLAHPCCQMLLSDLWQGGL 846 HSP 2 Score: 81.2629 bits (199), Expect = 4.329e-15 Identity = 83/362 (22.93%), Postives = 165/362 (45.58%), Query Frame = 3
Query: 2391 ITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLS----YFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGP-----------------CNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHA---FRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFEQ 3404
+++ K + FY+API + + ++I FL++ Y LV+ Q I S W+E Y++ Y+ + +E R+V + L +F+ N A ++ ++ + R S + R + + ++ ++ + + V + +GP I ++ +M+ ++ + I + +G+L +S+ YP +++ +L ++I P+F +GE+ D G C+ + VF+L TNVLL+N+++A Y F + + + +++ F R V E+ P PPP I YH F++I + K +F+Q L L P + K++ FE+
Sbjct: 1064 LSWKKKIMEFYKAPITTYWLWFFAFIWFLILLTYNLLVK---TQRIAS----WSEWYVFAYIFVWTLEIGRKVVSTIMMDTSKPVLKQLRVFFFQYRNGLLAFGLLTYLIAYFIRLSPTTK--TLGRILIICNSVIWSLKLVDYLSVQQGLGPYINIVAEMIPTMIPLCVLVFITLYAFGLLRQSITYPYEDWHWILVRNIFLQPYFMLYGEVYAAEIDTCGDEIWQTHEDENIPISMLNVTHETCVPGYWIAPVGLTVFMLATNVLLMNVMVAGCTYIFEKHIQSTREIFLFERYGQVMEYESTPWLPPPFTIIYHVIWLFKLIKSSSRMFERKNLFDQSLKLFLS---PDEMEKVHTFEE 1413
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Celegans
Match: gtl-2 (Gon-Two Like (TRP subfamily) [Source:UniProtKB/TrEMBL;Acc:Q20766]) HSP 1 Score: 121.709 bits (304), Expect = 1.735e-27 Identity = 138/595 (23.19%), Postives = 254/595 (42.69%), Query Frame = 3
Query: 1803 FSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRG-DNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDL----SPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGKNPK----DVPDAKNFHNKHLLDEN------AKAPPLKSEEI----TFIKAMSI--------------------FYRAP---------------IVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTW-NKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPN-SEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKL-IFEQENNLMLEHCKPSKSLKLNNFEQFCLN 3416
F++ DL +WA+L+ R ++ +W ++ + L A + K A + D ++L D + K ++ A ++ Q Y +T LL L W CL +A+ N FL H C+ ++W G L + +I P LF M P+ K + + P+ + + + +K P + E + ++ K ++I F R P I KF +++++FL L+E S+K E +IY +T ++E IR++ E + K + FY W N + + ++ F+ R +P R + S S +F ++ ++ V+ +GP I M M+ + + + ++ ++ +G+ ++L PN +++ LL ++I Y P+F +GE+ D G G C + +FLL+ N+LL+NLLIA+F +N E S+++W F R Q + E++ P PPP +IF H + I R P F E+++ L + ++ +FE+ C++
Sbjct: 639 FAYPFNDLLIWAVLTSRHGMAECMWVHGEDAMAKCLLAIRLYKATAKIAEDEYLDVEEAKRLFDNAVKCREDAIELLDQCYRADHDRTLRLLRMELPHWGNNNCLSLAVLANTKTFLAHPCCQILLAELWHGSLKVRSGSNVRVLTALICPPAILF------MAYKPKHSKTARLLSEETPEQLPYPRESITSTTSNRYRYSKGPEEQKETLLEKGSYTKKVTIISSRKNSGVASVYGSASSMMFKREPQLNKFERFRAFYSSPITKFWSWCIAFLIFLTTQTCILLLE-------TSLKPSKYEWITFIYTVTLSVEHIRKLMTSEGSRINEK-VKVFYAKWYNIWTSAALLFFLVGYGFRL-VPMYRHSWGRVLLSFSNVLFYMKIFEYLSVHPLLGPYIQMAAKMVWSMCYICVLLLVPLMAFGVNRQALTEPNVKDWHWLLVRNIFYKPYFMLYGEVYAGEIDTCGD-EGIRCFPGYFIPPLLMVIFLLVANILLLNLLIAIFNNIYNDSIEKSKEIWLFQRYQQLMEYHDSPFLPPPFSIFAHVYHFIDYLYNLRRPDTKRFRSEHSIKLS-VTEDEMKRIQDFEEDCID 1216 HSP 2 Score: 120.939 bits (302), Expect = 3.394e-27 Identity = 93/352 (26.42%), Postives = 159/352 (45.17%), Query Frame = 3
Query: 81 RSCYMEMKNTKSEITIKNGFEDQIQE-----FINKKFNTRTCYKYKEKSKDI--CHCNRHLNHHTNKSN------------SPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKV-ILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKK-QADGFLVQI---LFEGGRRAL--LNAYKAIKDKVPLVVIKGSGRVANMIS 1058
RS ++ K+T + N F ++ E +I F R C ++ KD C C R L+ HT S + W+ +NNT + FG I F G H H +++R D+ V LM W + P ++I+++GG+ N E + + F++G++ + W+I SGL +G+ + V++A+ E ++ Q+ IG++ WG +K +RL R N Y+ S V IL+ + FL D+GT ++ ++ EN + +G V + L EGG ++ ++ Y +K +P +V GSGR A++IS
Sbjct: 57 RSDHLSRKSTHKFLDNPNLFAIELTEKLSPPWIENTFEKRECIRFAALPKDPERCGCGRPLSAHTPASTFFSTLPVHLLEKEQQTWTIANNTQTSTTDAFGTIVFQGGA---HAHKAQYVRLSY----DSEPLDVMYLM--EKVWGLEAPRLVITVHGGMSNFE-LEERLGRLFRKGMLKAAQTTGAWIITSGLDSGVVRHVAKALDEAGISAR-MRSQIVTIGIAPWGVIKRKERLIRQ-------NEHVYYDVHSLSVNANVGILNDRHSYFLLADNGTVGRFGADLHLRQNLENHIATFGCNGRKVPVVCTLLEGGISSINAIHDYVTMKPDIPAIVCDGSGRAADIIS 390
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971]) HSP 1 Score: 102.449 bits (254), Expect = 1.460e-21 Identity = 91/387 (23.51%), Postives = 168/387 (43.41%), Query Frame = 3
Query: 57 NFIYIKLKRSCYMEMKNTKSEITIKNGFEDQIQEFINKKFNTRTCYKYKEKSKDI--CHCNRHLNHHTN--------------------------------------KSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIR--FDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVI-LDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF-------LVQILFEGGR---RALLNAYKAIKDKVPLVVIKGSGRVANMIS 1058
N + L + +M+ T+S +++ ++ + F R C ++ S+D+ C C R + H N K + E+WS +T + FG+++F G P H + +++R FD E A S++E + W I P +II+++GG N + + + F++GL+ W+I SG G+ K V+ A+ + Q ++++ IG++ WG +K + IG + Y +S KG+ L+ + FL D+GT +Y EV + E ++ ++ F +V ++ EGG R++L+ Y +VP+VV GSGR A++++
Sbjct: 155 NSAQLVLPTPLFNQMRFTESNMSLNR------HNWVRETFTRRECSRFIASSRDLHKCGCGRTRDAHRNIPELTSEFLRQKRSVAALEQQRSISNVNDDINTQNMYTKRGANEKWSLRKHTVSLATNAFGQVEFQGGP---HPYKAQYVRVNFDTEP---AYIMSLFEHV-----WQISPPRLIITVHGGTSNFD-LQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVAAALEGAQSAQ---RNKIVCIGIAPWGLLKKREDF-------IGQDKTVPYYPSS--SKGRFTGLNNRHSYFLLVDNGTVGRYGAEVILRKRLEMYISQKQKIFGGTRSVPVVCVVLEGGSCTIRSVLD-YVTNVPRVPVVVCDGSGRAADLLA 510 HSP 2 Score: 82.8037 bits (203), Expect = 1.733e-15 Identity = 93/365 (25.48%), Postives = 170/365 (46.58%), Query Frame = 3
Query: 2418 FYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMIC-------RCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGP-------CNGTDCIVSSGTVLIS-----------FAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIIS-LPCKSRCPKLIFEQENNLMLEHC-----KPSKSLKLNNFEQFCLNE 3419
FY API F +S+I+F+ F Y LV+ P + E + YV F +E++R++ + K +Y WN + II F I FM C R + + ++ ++ + + V+ +GP + M M++++ + + + V+ ++++G+ +S+ YP+ ++ +L ++I P+F +GE+ + D G NG I+ +GT +S FLL+ N+LL+++LIA+F + F+ E S+++W F R + V E+ P PPPL YH I+ + + C K QE N M + + KL++FE+ C+ +
Sbjct: 1201 FYSAPISTFWSWTISFILFITFFTYTLLVKTPP-------RPTVIEYILIAYVAAFGLEQVRKIIMSDAKPFYEKIRTYVCSFWNCVTILAII---------FYI-VGFFMRCFGSVAYGRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWILVRNIFLKPYFMLYGEVYADEIDTCGDEAWDQHLENGGPVILGNGTTGLSCVPGYWIPPLLMTFFLLIANILLMSMLIAIFNHIFDATDEMSQQIWLFQRYKQVMEYESTPFLPPPLTPLYHGVLILQFVRTRLSCSK---SQERNPMFDFSLKLFLDNDQIEKLHDFEEDCMED 1545 HSP 3 Score: 68.9366 bits (167), Expect = 2.275e-11 Identity = 43/162 (26.54%), Postives = 80/162 (49.38%), Query Frame = 3
Query: 1734 RDFLTDSFEEFAMLYESDVDAHK--FSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQD----LASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDL 2201
RD ++ EE ++ SD + F + +L +WA+L+ R D++M +W+ + + AL A + K +A ++ L+ ++ + KKY + L+ ++ Y+ ++T LL L+ W+ TCL +A+ N FL H C+ +W G L
Sbjct: 823 RDCGSEFDEELSLTSASDGSQTEPDFRYPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEA---AEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGL 981
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971]) HSP 1 Score: 102.449 bits (254), Expect = 1.640e-21 Identity = 91/387 (23.51%), Postives = 168/387 (43.41%), Query Frame = 3
Query: 57 NFIYIKLKRSCYMEMKNTKSEITIKNGFEDQIQEFINKKFNTRTCYKYKEKSKDI--CHCNRHLNHHTN--------------------------------------KSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIR--FDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVI-LDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF-------LVQILFEGGR---RALLNAYKAIKDKVPLVVIKGSGRVANMIS 1058
N + L + +M+ T+S +++ ++ + F R C ++ S+D+ C C R + H N K + E+WS +T + FG+++F G P H + +++R FD E A S++E + W I P +II+++GG N + + + F++GL+ W+I SG G+ K V+ A+ + Q ++++ IG++ WG +K + IG + Y +S KG+ L+ + FL D+GT +Y EV + E ++ ++ F +V ++ EGG R++L+ Y +VP+VV GSGR A++++
Sbjct: 256 NSAQLVLPTPLFNQMRFTESNMSLNR------HNWVRETFTRRECSRFIASSRDLHKCGCGRTRDAHRNIPELTSEFLRQKRSVAALEQQRSISNVNDDINTQNMYTKRGANEKWSLRKHTVSLATNAFGQVEFQGGP---HPYKAQYVRVNFDTEP---AYIMSLFEHV-----WQISPPRLIITVHGGTSNFD-LQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVAAALEGAQSAQ---RNKIVCIGIAPWGLLKKREDF-------IGQDKTVPYYPSS--SKGRFTGLNNRHSYFLLVDNGTVGRYGAEVILRKRLEMYISQKQKIFGGTRSVPVVCVVLEGGSCTIRSVLD-YVTNVPRVPVVVCDGSGRAADLLA 611 HSP 2 Score: 82.4185 bits (202), Expect = 1.843e-15 Identity = 93/365 (25.48%), Postives = 170/365 (46.58%), Query Frame = 3
Query: 2418 FYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMIC-------RCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGP-------CNGTDCIVSSGTVLIS-----------FAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIIS-LPCKSRCPKLIFEQENNLMLEHC-----KPSKSLKLNNFEQFCLNE 3419
FY API F +S+I+F+ F Y LV+ P + E + YV F +E++R++ + K +Y WN + II F I FM C R + + ++ ++ + + V+ +GP + M M++++ + + + V+ ++++G+ +S+ YP+ ++ +L ++I P+F +GE+ + D G NG I+ +GT +S FLL+ N+LL+++LIA+F + F+ E S+++W F R + V E+ P PPPL YH I+ + + C K QE N M + + KL++FE+ C+ +
Sbjct: 1302 FYSAPISTFWSWTISFILFITFFTYTLLVKTPP-------RPTVIEYILIAYVAAFGLEQVRKIIMSDAKPFYEKIRTYVCSFWNCVTILAII---------FYI-VGFFMRCFGSVAYGRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWILVRNIFLKPYFMLYGEVYADEIDTCGDEAWDQHLENGGPVILGNGTTGLSCVPGYWIPPLLMTFFLLIANILLMSMLIAIFNHIFDATDEMSQQIWLFQRYKQVMEYESTPFLPPPLTPLYHGVLILQFVRTRLSCSK---SQERNPMFDFSLKLFLDNDQIEKLHDFEEDCMED 1646 HSP 3 Score: 69.3218 bits (168), Expect = 1.988e-11 Identity = 43/162 (26.54%), Postives = 80/162 (49.38%), Query Frame = 3
Query: 1734 RDFLTDSFEEFAMLYESDVDAHK--FSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQD----LASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDL 2201
RD ++ EE ++ SD + F + +L +WA+L+ R D++M +W+ + + AL A + K +A ++ L+ ++ + KKY + L+ ++ Y+ ++T LL L+ W+ TCL +A+ N FL H C+ +W G L
Sbjct: 924 RDCGSEFDEELSLTSASDGSQTEPDFRYPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEA---AEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGL 1082
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971]) HSP 1 Score: 102.449 bits (254), Expect = 1.725e-21 Identity = 91/387 (23.51%), Postives = 168/387 (43.41%), Query Frame = 3
Query: 57 NFIYIKLKRSCYMEMKNTKSEITIKNGFEDQIQEFINKKFNTRTCYKYKEKSKDI--CHCNRHLNHHTN--------------------------------------KSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIR--FDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVI-LDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF-------LVQILFEGGR---RALLNAYKAIKDKVPLVVIKGSGRVANMIS 1058
N + L + +M+ T+S +++ ++ + F R C ++ S+D+ C C R + H N K + E+WS +T + FG+++F G P H + +++R FD E A S++E + W I P +II+++GG N + + + F++GL+ W+I SG G+ K V+ A+ + Q ++++ IG++ WG +K + IG + Y +S KG+ L+ + FL D+GT +Y EV + E ++ ++ F +V ++ EGG R++L+ Y +VP+VV GSGR A++++
Sbjct: 195 NSAQLVLPTPLFNQMRFTESNMSLNR------HNWVRETFTRRECSRFIASSRDLHKCGCGRTRDAHRNIPELTSEFLRQKRSVAALEQQRSISNVNDDINTQNMYTKRGANEKWSLRKHTVSLATNAFGQVEFQGGP---HPYKAQYVRVNFDTEP---AYIMSLFEHV-----WQISPPRLIITVHGGTSNFD-LQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVAAALEGAQSAQ---RNKIVCIGIAPWGLLKKREDF-------IGQDKTVPYYPSS--SKGRFTGLNNRHSYFLLVDNGTVGRYGAEVILRKRLEMYISQKQKIFGGTRSVPVVCVVLEGGSCTIRSVLD-YVTNVPRVPVVVCDGSGRAADLLA 550 HSP 2 Score: 82.8037 bits (203), Expect = 1.712e-15 Identity = 93/365 (25.48%), Postives = 170/365 (46.58%), Query Frame = 3
Query: 2418 FYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMIC-------RCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGP-------CNGTDCIVSSGTVLIS-----------FAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIIS-LPCKSRCPKLIFEQENNLMLEHC-----KPSKSLKLNNFEQFCLNE 3419
FY API F +S+I+F+ F Y LV+ P + E + YV F +E++R++ + K +Y WN + II F I FM C R + + ++ ++ + + V+ +GP + M M++++ + + + V+ ++++G+ +S+ YP+ ++ +L ++I P+F +GE+ + D G NG I+ +GT +S FLL+ N+LL+++LIA+F + F+ E S+++W F R + V E+ P PPPL YH I+ + + C K QE N M + + KL++FE+ C+ +
Sbjct: 1241 FYSAPISTFWSWTISFILFITFFTYTLLVKTPP-------RPTVIEYILIAYVAAFGLEQVRKIIMSDAKPFYEKIRTYVCSFWNCVTILAII---------FYI-VGFFMRCFGSVAYGRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWILVRNIFLKPYFMLYGEVYADEIDTCGDEAWDQHLENGGPVILGNGTTGLSCVPGYWIPPLLMTFFLLIANILLMSMLIAIFNHIFDATDEMSQQIWLFQRYKQVMEYESTPFLPPPLTPLYHGVLILQFVRTRLSCSK---SQERNPMFDFSLKLFLDNDQIEKLHDFEEDCMED 1585 HSP 3 Score: 68.9366 bits (167), Expect = 2.263e-11 Identity = 43/162 (26.54%), Postives = 80/162 (49.38%), Query Frame = 3
Query: 1734 RDFLTDSFEEFAMLYESDVDAHK--FSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQD----LASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDL 2201
RD ++ EE ++ SD + F + +L +WA+L+ R D++M +W+ + + AL A + K +A ++ L+ ++ + KKY + L+ ++ Y+ ++T LL L+ W+ TCL +A+ N FL H C+ +W G L
Sbjct: 863 RDCGSEFDEELSLTSASDGSQTEPDFRYPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEA---AEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGL 1021
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339082) HSP 1 Score: 251.521 bits (641), Expect = 1.993e-67 Identity = 287/1243 (23.09%), Postives = 543/1243 (43.68%), Query Frame = 3
Query: 147 QIQEFINKKFNTRTCYKYKEKSKDICHC---NRHLNHHTN---KSNSPEE-WSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKK-------QADGFLVQILFEGGRRALLNAYKAIKDK--VPLVVIKGSGRVANMISEVMGLPSKNYKESI-----EFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMD----ANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIE----------RDFLTDSFEEFA-----------MLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMA------DLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPT-WKIIITIPFSLFLMKL--------MIMPSFPRK---------GKNPKDVPDA------------KNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTD-----CIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFEQFCL------NESILEXXXXXXXXXXXXXXETDFFGKVNVKHEVPDVNSSQ-LETATSYQVRLEYKLEKME 3593
Q + +I F R C K+ KD C + H T +S SP + W + +T +G I+F G H +++R D + +L T WN+ P ++I++ GG N + + KK+ ++GL+ K W+ G + G+ K V +A+ + +V IG++ WG V+ N L +G N + S +L+ + FL D+GT+ +Y E+ K E F+ + +V ++ EGG + + + D VP+VV GSGR A++++ V S ++ + ++++ + T ++ + E+ L++ N K I ++ + + D+ IL A+ S L L + +N +IA +F + E + E + +L+ ++ +FV L +EN + F+ L+ELY +++ P A L + RD + + L D G +I KL G + Y++ +P+ R T ++ +A + + S++ +F ++ +L +WA+L+ R +++++W + + +L + + K MA DL D + +L +K+++ + ++ +Y + K LL L W+ +CL +A+ N L H + +WMG L T +K+I+ + ++ +L MP + + + PDA + F N +E + PL+ K FY API KF ++Y+ FL++F++ LV+++ + W E Y Y+ T E++R++ E HKF + + WN D II+F+ + RF +N I R ++ + + +R + VNK +GP + M+ M++++++F+ + + ++++G+ +++ YPN + L K++ + P+F +GE+ + D PC G D C+ I+ +++LL+ N+LLINLLIA+F FN++ S ++W F R +V E+ KP+ PPP H + ++ C + L +++N L L + +L +FE+ C+ E IL + + ET + ++ D+N + ++TAT + E++L KME
Sbjct: 11 QPRSWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGGA---HPTKAQYVRLSF----DTRPELLVQLFTKE--WNLELPKLLITVQGGKANFD-LQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL---LLEGQQRTGRVVSIGIAPWGIVERNHEL-------LGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLD-----QSEKLYQELLQCTRN-KNLITVFRIQEKPEGEAQELDQTILTALFKSQHLSPPEQLSLALTWNRVDIARSEIFVYGQ--EWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELY----NTKHGP-ANTLGYILRDVRPHIPKGYIYT------LHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFN--ELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDL-----DTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEVSLTDSDTAQFREFFNLSEYNEVKQHQPLR-----LKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPR-------WQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRFR--ENTMDIGRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGDIDP--PC-GEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKY-CVRKAKGLEVQRDNGLKL-FLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVET-------MSQKIEDINQKENIQTATVQNI--EFRLRKME 1179
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339074) HSP 1 Score: 246.899 bits (629), Expect = 5.350e-66 Identity = 287/1266 (22.67%), Postives = 548/1266 (43.29%), Query Frame = 3
Query: 120 ITIKNGFEDQIQEFINKKFNTRTCYKYKEKSKDICHC---NRHLNHHTN---KSNSPEE-WSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKK-------QADGFLVQILFEGGRRALLNAYKAIKDK--VPLVVIKGSGRVANMISEVMGLPSKNYKESI-----EFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMD----ANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIE----------RDFLTDSFEEFA-----------MLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMA------DLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPT-WKIIITIPFSLFLMKL--------MIMPSFPRK---------GKNPKDVPDAKNFHNKHL------LDENAKAPPLKSEEITFIKAMSI--------------------FYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTD-----CIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFEQFCL------NESILEXXXXXXXXXXXXXXETDFFGKVNVKHEVPDVNSSQ-LETATSYQVRLEYKLEKME 3593
+ +K + Q + +I F R C K+ KD C + H T +S SP + W + +T +G I+F G H +++R D + +L T WN+ P ++I++ GG N + + KK+ ++GL+ K W+ G + G+ K V +A+ + +V IG++ WG V+ N L +G N + S +L+ + FL D+GT+ +Y E+ K E F+ + +V ++ EGG + + + D VP+VV GSGR A++++ V S ++ + ++++ + T ++ + E+ L++ N K I ++ + + D+ IL A+ S L L + +N +IA +F + E + E + +L+ ++ +FV L +EN + F+ L+ELY +++ P A L + RD + + L D G +I KL G + Y++ +P+ R T ++ +A + + S++ +F ++ +L +WA+L+ R +++++W + + +L + + K MA DL D + +L +K+++ + ++ +Y + K LL L W+ +CL +A+ N L H + +WMG L T +K+I+ + ++ +L MP + + + PDA+ + EN K S+ F + ++ FY API KF ++Y+ FL++F++ LV+++ + W E Y Y+ T E++R++ E HKF + + WN D II+F+ + RF +N I R ++ + + +R + VNK +GP + M+ M++++++F+ + + ++++G+ +++ YPN + L K++ + P+F +GE+ + D PC G D C+ I+ +++LL+ N+LLINLLIA+F FN++ S ++W F R +V E+ KP+ PPP H + ++ C + L +++N L L + +L +FE+ C+ E IL + + ET + ++ D+N + ++TAT + E++L KME
Sbjct: 20 VPVKKPVKHQPRSWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGGA---HPTKAQYVRLSF----DTRPELLVQLFTKE--WNLELPKLLITVQGGKANFD-LQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL---LLEGQQRTGRVVSIGIAPWGIVERNHEL-------LGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLD-----QSEKLYQELLQCTRN-KNLITVFRIQEKPEGEAQELDQTILTALFKSQHLSPPEQLSLALTWNRVDIARSEIFVYGQ--EWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELY----NTKHGP-ANTLGYILRDVRPHIPKGYIYT------LHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFN--ELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDL-----DTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPR-------WQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRFR--ENTMDIGRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGDID--PPC-GEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKY-CVRKAKGLEVQRDNGLKL-FLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVET-------MSQKIEDINQKENIQTATVQNI--EFRLRKME 1216
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339076) HSP 1 Score: 244.588 bits (623), Expect = 3.163e-65 Identity = 286/1257 (22.75%), Postives = 544/1257 (43.28%), Query Frame = 3
Query: 147 QIQEFINKKFNTRTCYKYKEKSKDICHC---NRHLNHHTN---KSNSPEE-WSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKK-------QADGFLVQILFEGGRRALLNAYKAIKDK--VPLVVIKGSGRVANMISEVMGLPSKNYKESI-----EFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMD----ANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIE----------RDFLTDSFEEFA-----------MLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMA------DLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPT-WKIIITIPFSLFLMKL--------MIMPSFPRK---------GKNPKDVPDAKNFHNKHL------LDENAKAPPLKSEEITFIKAMSI--------------------FYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTD-----CIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFEQFCL------NESILEXXXXXXXXXXXXXXETDFFGKVNVKHEVPDVNSSQ-LETATSYQVRLEYKLEKME 3593
Q + +I F R C K+ KD C + H T +S SP + W + +T +G I+F G H +++R D + +L T WN+ P ++I++ GG N + + KK+ ++GL+ K W+ G + G+ K V +A+ + +V IG++ WG V+ N L +G N + S +L+ + FL D+GT+ +Y E+ K E F+ + +V ++ EGG + + + D VP+VV GSGR A++++ V S ++ + ++++ + T ++ + E+ L++ N K I ++ + + D+ IL A+ S L L + +N +IA +F + E + E + +L+ ++ +FV L +EN + F+ L+ELY +++ P A L + RD + + L D G +I KL G + Y++ +P+ R T ++ +A + + S++ +F ++ +L +WA+L+ R +++++W + + +L + + K MA DL D + +L +K+++ + ++ +Y + K LL L W+ +CL +A+ N L H + +WMG L T +K+I+ + ++ +L MP + + + PDA+ + EN K S+ F + ++ FY API KF ++Y+ FL++F++ LV+++ + W E Y Y+ T E++R++ E HKF + + WN D II+F+ + RF +N I R ++ + + +R + VNK +GP + M+ M++++++F+ + + ++++G+ +++ YPN + L K++ + P+F +GE+ + D PC G D C+ I+ +++LL+ N+LLINLLIA+F FN++ S ++W F R +V E+ KP+ PPP H + ++ C + L +++N L L + +L +FE+ C+ E IL + + ET + ++ D+N + ++TAT + E++L KME
Sbjct: 11 QPRSWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGGA---HPTKAQYVRLSF----DTRPELLVQLFTKE--WNLELPKLLITVQGGKANFD-LQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL---LLEGQQRTGRVVSIGIAPWGIVERNHEL-------LGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLD-----QSEKLYQELLQCTRN-KNLITVFRIQEKPEGEAQELDQTILTALFKSQHLSPPEQLSLALTWNRVDIARSEIFVYGQ--EWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELY----NTKHGP-ANTLGYILRDVRPHIPKGYIYT------LHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFN--ELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDL-----DTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPR-------WQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRFR--ENTMDIGRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGDID--PPC-GEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKY-CVRKAKGLEVQRDNGLKL-FLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVET-------MSQKIEDINQKENIQTATVQNI--EFRLRKME 1198
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339077) HSP 1 Score: 244.202 bits (622), Expect = 3.803e-65 Identity = 287/1259 (22.80%), Postives = 545/1259 (43.29%), Query Frame = 3
Query: 141 EDQIQEFINKKFNTRTCYKYKEKSKDICHC---NRHLNHHTN---KSNSPEE-WSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKK-------QADGFLVQILFEGGRRALLNAYKAIKDK--VPLVVIKGSGRVANMISEVMGLPSKNYKESI-----EFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMD----ANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIE----------RDFLTDSFEEFA-----------MLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMA------DLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPT-WKIIITIPFSLFLMKL--------MIMPSFPRK---------GKNPKDVPDAKNFHNKHL------LDENAKAPPLKSEEITFIKAMSI--------------------FYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTD-----CIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFEQFCL------NESILEXXXXXXXXXXXXXXETDFFGKVNVKHEVPDVNSSQ-LETATSYQVRLEYKLEKME 3593
E Q + +I F R C K+ KD C + H T +S SP + W + +T +G I+F G H +++R D + +L T WN+ P ++I++ GG N + + KK+ ++GL+ K W+ G + G+ K V +A+ + +V IG++ WG V+ N L +G N + S +L+ + FL D+GT+ +Y E+ K E F+ + +V ++ EGG + + + D VP+VV GSGR A++++ V S ++ + ++++ + T ++ + E+ L++ N K I ++ + + D+ IL A+ S L L + +N +IA +F + E + E + +L+ ++ +FV L +EN + F+ L+ELY +++ P A L + RD + + L D G +I KL G + Y++ +P+ R T ++ +A + + S++ +F ++ +L +WA+L+ R +++++W + + +L + + K MA DL D + +L +K+++ + ++ +Y + K LL L W+ +CL +A+ N L H + +WMG L T +K+I+ + ++ +L MP + + + PDA+ + EN K S+ F + ++ FY API KF ++Y+ FL++F++ LV+++ + W E Y Y+ T E++R++ E HKF + + WN D II+F+ + RF +N I R ++ + + +R + VNK +GP + M+ M++++++F+ + + ++++G+ +++ YPN + L K++ + P+F +GE+ + D PC G D C+ I+ +++LL+ N+LLINLLIA+F FN++ S ++W F R +V E+ KP+ PPP H + ++ C + L +++N L L + +L +FE+ C+ E IL + + ET + ++ D+N + ++TAT + E++L KME
Sbjct: 111 EHQPRSWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGGA---HPTKAQYVRLSF----DTRPELLVQLFTKE--WNLELPKLLITVQGGKANFD-LQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL---LLEGQQRTGRVVSIGIAPWGIVERNHEL-------LGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLD-----QSEKLYQELLQCTRN-KNLITVFRIQEKPEGEAQELDQTILTALFKSQHLSPPEQLSLALTWNRVDIARSEIFVYGQ--EWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELY----NTKHGP-ANTLGYILRDVRPHIPKGYIYT------LHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFN--ELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDL-----DTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPR-------WQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRFR--ENTMDIGRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGDID--PPC-GEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKY-CVRKAKGLEVQRDNGLKL-FLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVET-------MSQKIEDINQKENIQTATVQNI--EFRLRKME 1300
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339079) HSP 1 Score: 243.817 bits (621), Expect = 5.173e-65 Identity = 286/1257 (22.75%), Postives = 544/1257 (43.28%), Query Frame = 3
Query: 147 QIQEFINKKFNTRTCYKYKEKSKDICHC---NRHLNHHTN---KSNSPEE-WSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKK-------QADGFLVQILFEGGRRALLNAYKAIKDK--VPLVVIKGSGRVANMISEVMGLPSKNYKESI-----EFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMD----ANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIE----------RDFLTDSFEEFA-----------MLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMA------DLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPT-WKIIITIPFSLFLMKL--------MIMPSFPRK---------GKNPKDVPDAKNFHNKHL------LDENAKAPPLKSEEITFIKAMSI--------------------FYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTD-----CIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFEQFCL------NESILEXXXXXXXXXXXXXXETDFFGKVNVKHEVPDVNSSQ-LETATSYQVRLEYKLEKME 3593
Q + +I F R C K+ KD C + H T +S SP + W + +T +G I+F G H +++R D + +L T WN+ P ++I++ GG N + + KK+ ++GL+ K W+ G + G+ K V +A+ + +V IG++ WG V+ N L +G N + S +L+ + FL D+GT+ +Y E+ K E F+ + +V ++ EGG + + + D VP+VV GSGR A++++ V S ++ + ++++ + T ++ + E+ L++ N K I ++ + + D+ IL A+ S L L + +N +IA +F + E + E + +L+ ++ +FV L +EN + F+ L+ELY +++ P A L + RD + + L D G +I KL G + Y++ +P+ R T ++ +A + + S++ +F ++ +L +WA+L+ R +++++W + + +L + + K MA DL D + +L +K+++ + ++ +Y + K LL L W+ +CL +A+ N L H + +WMG L T +K+I+ + ++ +L MP + + + PDA+ + EN K S+ F + ++ FY API KF ++Y+ FL++F++ LV+++ + W E Y Y+ T E++R++ E HKF + + WN D II+F+ + RF +N I R ++ + + +R + VNK +GP + M+ M++++++F+ + + ++++G+ +++ YPN + L K++ + P+F +GE+ + D PC G D C+ I+ +++LL+ N+LLINLLIA+F FN++ S ++W F R +V E+ KP+ PPP H + ++ C + L +++N L L + +L +FE+ C+ E IL + + ET + ++ D+N + ++TAT + E++L KME
Sbjct: 18 QPRSWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGGA---HPTKAQYVRLSF----DTRPELLVQLFTKE--WNLELPKLLITVQGGKANFD-LQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL---LLEGQQRTGRVVSIGIAPWGIVERNHEL-------LGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLD-----QSEKLYQELLQCTRN-KNLITVFRIQEKPEGEAQELDQTILTALFKSQHLSPPEQLSLALTWNRVDIARSEIFVYGQ--EWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELY----NTKHGP-ANTLGYILRDVRPHIPKGYIYT------LHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFN--ELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDL-----DTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPR-------WQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRFR--ENTMDIGRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGDID--PPC-GEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKY-CVRKAKGLEVQRDNGLKL-FLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVET-------MSQKIEDINQKENIQTATVQNI--EFRLRKME 1205
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Zebrafish
Match: trpm2 (transient receptor potential cation channel, subfamily M, member 2 [Source:NCBI gene;Acc:799412]) HSP 1 Score: 280.796 bits (717), Expect = 8.779e-77 Identity = 276/1130 (24.42%), Postives = 503/1130 (44.51%), Query Frame = 3
Query: 150 IQEFINKKFNTRTCYKYKEKSKDICHCNRHLNHHTNKSNSPE-----EWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVF-KYENTSEDEKGKV-ILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADG--------FLVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMM-----------DANMSFDKKILQAMIVGADKS-------MKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQL------FDKPLIERDFLTDSFEEFAMLYES----DVDAHKFSWST-------QDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGKNPKDV-----------------PDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF-DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELM--LEN--FDVAG-PCNGTD-----C---------IVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
I+E I KK C+ ++ + IC C H +++ PE +W + FG I F G + K++R D +C ++Y+LMT W + P ++IS+ GG KN I H K KF++GLI V + W++ G AG+ K V A+ ++ ++ Q+ +IGV+ WG + N L I F Y + E +G++ LD + FL DDGT+ Y E+E + E + K + G +V ++ +GG L Y ++ + P VV++GSGR+A++I+ V +P +K+T+ + + ++E+ N+ + K+I M D N D ILQA++ + +R L+L + +N +IA+ +F++ + + +L +KP F N ++E E E LC+L+ S F L K + + ++ + + L++ ++ F +PL + ++ + S D+ WS +DLFLWA++ +L+ I W ++ I +AL A+ IL+K+A D+ ++ + + Y+ A + ++ ++ + LL+R W TCL +A+ + F+ HS ++ T++W G+LS P WK+++ + F F + +F R + D K + + ++ PL + MS F ++P VKF ++ SY FL +FA +++ + W E+ +Y+++ + EEIRQ++ D + +G + K Y WN D + I++FIA ++ R F I + + I +F +R M + +++++GPKII++R M+ D+ FF+ + I+V+ YG+ + + N E + + VY P+ FG ++N FD++ N +D C + ++ V+LL N+LL+NLLIA+F YTF ++Q++++ +W F R +L++E++ +P PPP + H
Sbjct: 40 IKENIKKK---ECCFYVEDGREGICKCGYPKVQHCDEAIKPEDYMGEQWDKHRHVRETPTDAFGDISFGGL----GQKTGKYVRVSS----DTSCENLYQLMTEQ--WKLRSPNLLISVTGGAKNF-YIKTHLKDKFRRGLIKVAQTTGAWILTGGTHAGVMKHVGMAVRDYTLSSGSMEGQIVVIGVAPWGVIHNRSTL-------IHPEGRFPAYYSLDEQGQGRLSCLDINHTHFLLVDDGTQGHYGVEIELRARLEKLISKLSLGNRESGVTIPVVCVVLDGGPGTLNTIYNSMLNHTPCVVLEGSGRLADVIAHVASVPV-------------SKVTMALINRLLKRFFMQEYKNFTELQIIEWTKKIQDILRMPHLLTVFRIDEDKNYDVDVAILQALLKASRSDEHAGRHCWERQLELAVAWNRVDIAESEIFTEE--SQWTSSDLHPAMFSALVGDKP---------EFVRLLLENGVCVREFLERE---------ETLCELYSHLPSCFFLRKLAKRVQGGKMRRGQEPLPGSRKVCLSHVSEEVRHLLGSFTQPLYIASRYKPTKDDVRLKVPSKGALDLPCSGEEWSADTVWDPGRDLFLWAVVQNNRELAEIGWEQCRDCIAAALAASKILRKLAQES-GEDDSEEATEMLELANHYEKQAIGVFSECHSWDAQRAQKLLIRISPSWGRSTCLWLALEAHDKSFIAHSGVQALLTQIWCGELSVDNPHWKVLLCMIF--FPLIYTGFLTFRRDEDIQRQAERTEQQKLAMESVFAGQSDGKIKRHLRGFSQKSELKPLNCSS----RLMS-FLKSPQVKFYWNIASYFGFLWLFAVVLMIDFQ-------TSPSWRELLLYVWLTSLVCEEIRQLYHDFDGSGFRRKAKMYIKDLWNILDVLSIVLFIAGLICRLQASDTVFYIGKVILCIDFIIFCLRLMAIFSISRTLGPKIIIVRRMMLDLFFFMFLLSIWVVAYGVAKQGILIENEERLNWIIRGAVYEPYITIFGNFPTNIDNTLFDISSCSVNASDPLKPKCPMLNADNTPVFPEWLTIMMLCVYLLFANILLLNLLIAIFNYTFQEVQDNTDTIWKFQRYELIKEYHSRPALPPPFILLSH 1100
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Zebrafish
Match: trpm6 (transient receptor potential cation channel, subfamily M, member 6 [Source:ZFIN;Acc:ZDB-GENE-111212-1]) HSP 1 Score: 246.128 bits (627), Expect = 1.339e-65 Identity = 266/1128 (23.58%), Postives = 490/1128 (43.44%), Query Frame = 3
Query: 159 FINKKFNTRTCYKYKEKSKD---------------ICHCNRHLNHHT------------NKSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQ-------ADGFLVQILFEGGRRAL--LNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYK--ESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMS-FDKKILQAMIVGADKSMKRTLKLCIRFNCSNIA-DKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDT-KSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQY-------------------SQLFDK-----PLIERDFLTDSFEEFAMLY---ESDVDAHK--------FSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKK----YQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENA---KAPPLKSEEIT-----FIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
+I F R C ++ S+D C C R + H + S EEWS +T+L FG + F G K++R C D+ + +LM W++ P ++I+++GG N +S + F GL+ + W++ G++ G+ K V +A+ + H ++ ++G++ WG ++NN L IG + + Y+ + L+ ++ FL DDGT + ++E + E + Q LV ++ EGG L + Y VP++V +G+GR A+M++ + + + K I+ VL+ +Q G E +E E + L+E ++ I I+D ++ D IL + G S + L L + ++ ++IA D I+ ++ LE ++ L +L ++ FV L +EN + +F+ + L++LY I S ++ D + + ++++ L D G +I L G + Y S F K P E F A Y E V F + DLF+WA+L R +++++LW+ + + A+ A + + +A + ++N+ + + KK + LA ++ QA+ +++ LL + W+ TCLQ+A++ + F+ H+ + T +WMG L+ +W II ++L+ S P+ + +A F + E KA P E + + + + FY AP+VKF H ++++ FLM+FAY LV L I+ E + Y+L A+E+ R+V E K +F WN D + I++F+ V R+ Q + ++S+ + +R + + VN+ GP + MI M+ ++ + + I + ++++G +S+ PN + + L +D+V+ P++ FGE+ D N C+ + + AV+L + ++++NLLIA F +N++ S KLW + R + + + KP PPPL H
Sbjct: 6 WIQATFCKRECVRFLPASRDHHRCYPVCQVCQSLVRCCCGRLIAEHVGPYSGLLGHDPGSGSAEEEEWSVLQHTSLSPTDAFGSLDFQGSSKRACR--AKYVRLSC----DSPPELLVQLMLRE--WHMEIPKLVITVHGGTDNF-LLSPRVCQAFSTGLVTAAESTGAWILTDGINTGVSKYVGDAVKMYGSHDHRKRN---VVGITPWGIIENNSDL-------IGRDGLRHYQALGNPLSKRASLNGMHSHFLLVDDGTIGKSGCQIELRKRLERHIHYQKIHPRLPQHVPLVCVVVEGGPSVLSVVLEYVCRTSPVPVLVFEGTGRAADMLALIHKQTAVDRKLDSDIKEDVLQR---IQDSFGVER-SESTELLDILMECM-EHRELISIFDSESEDLQEADVAILSTSLRGTRASPEEQLSLTLAWDRADIAKDHILVYGQQWQVGSLE---QIMLDALIMDRVNFVKLLIENGMTMSHFLTISRLEQLYNIQTGSSHHFLRHVIADAKQTRLPAVYRIS----------LIDIGMVIEYLIGGAYRSTYTRKRFRTMYSRLHNPAKETSSPFSKAKKVAPAPEATPPRSHFRRTAQPYRHQEGGVAPQDQKSDPIPDFVCTFNDLFVWAVLKHRQEMALLLWQHGEQAMARAVVACKLYRTLA---MEAKESNMGDTMAEELKKNSLEFGQLAVDVLDQAFRENERMAMKLLTWEMKDWSNFTCLQMAVSSGLRPFVAHNCTQMLLTDLWMGRLNLSKNSWFKIIGSILMPVAIQLLEFKSQAEMSHVPQ-LQEALQFGWDTVPSEQEGAEKAVPGDEERGSSCLYPWTRKVYDFYTAPVVKFWFHTMAFLGFLMMFAYTCLVRLNETPNIQ-------ECLVMTYILAMAVEKAREVLVLEPRKFTKKLKVWFSEYWNINDFLGILLFLVGVSLRWH--QETRLASHIVYSLDFVFWSVRLLDLFAVNQHAGPYLTMITKMMSNMFYIVIIMALVLVSFGTSRKSILSPNEDPSWTLLRDVVFQPYWMIFGEVYAGEIDACA--NPETCVPGAFLTIFLQAVYLFIQYIIMVNLLIAFFNNVYNEMSTISRKLWKYNRYRYIMTYQEKPWLPPPLIFLSH 1081
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Zebrafish
Match: trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:ZFIN;Acc:ZDB-GENE-060503-736]) HSP 1 Score: 240.736 bits (613), Expect = 1.942e-64 Identity = 273/1050 (26.00%), Postives = 483/1050 (46.00%), Query Frame = 3
Query: 318 KFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVI-LDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF---------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPE--EDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRT------LKLCIRFNCSNIADKIVFS-DPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDI--------IAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIIT--IPFSLF--LMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLL-------DENAKAPPLKSEEITFIKAM----SIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF--DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVA-------------------GPCNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
+ G I F+G KF+R D +Y+++T W + P +++++ GG + + + ++GL+ + W++ SGL GI K + +A+ + K +V IG++ W ++N L L+AK + E+ G V LD + F+ D+ K+ E +K + Q G+ ++ +L G R L YK I++ +P +++ GSG VA+++ +M + IV E L I T P+ E+ +T L++ + + ++D + + D IL+A++ + LKL + +N +IA +FS D ++ LE E+ + +L ++KP+FV LFV+N ++ F+ L+ELY SEK LL L ++ + +L +K S N + GD ++K+ + L++ + K ER F L + D + W +DLFLWA+L R +++ W + + +AL I+K+MA L + R + +A KY+ A + ++ Y+ S+ + Y+LLVR W+ T L IA F H ++ TKVW G + ++++T IP ++ L+K + P D+ LL E + +S TFI+ + + F+ AP+ F +++ Y FL++F+Y L++ +P AEI +Y +V T +EEIRQ F D++++ K K Y WNK D V I +F+ + R ++ + + R + ++ +F +R + + ++K +GPKII++ M++D+ FFL +++I YG+ ++L +PN +F+ +Y P+ FG++ LE D A PC I ++ V++ ++LL+TNVLL+NLLIAMF YTF +QE+++ W F R L+ E++ +P PP I H
Sbjct: 16 RLGDIDFTGVSRTRG----KFVRVTSSTDP----AEIYQILTKQ--WGLAPPHLVVALMGG-DEVAQLKPWLRDTLRKGLVKAAQSTGAWILTSGLRFGITKNLGQAVRDHSLASTSPKVRVVAIGIAPWNMIQNRDLL---LSAKPDHPATYPTEDLP---YGAVYSLDCNHSHFILVDEDP-KRPGATGEMRVKMLKHISLQRTGYGGTGSIEIPVLCLLVHGEPRILQKMYKNIQNSIPWLILAGSGGVADILVTLMDRGCWDAD-----IVQE----LLINTFPDGLHSTEITSWTK-LIQRILDHGHLLTVHDP-EQDSELDTVILKALVKACKSQSQEAQDFLDELKLAVAWNRVDIAKSEIFSGDVQWSAQDLE---EVMMEALVNDKPDFVRLFVDNGVNIKQFLTYGRLQELY--CSVSEKNLLHTLL--LKKNQERQAQLARKRMSGNPNN--ELGDRKFRFTFHEVSKVLKDFLDDTCKGFYQKLPAERMGKGRLFHSQKNLPDMDRRC-EHPW--RDLFLWAILQNRQEMANYFWAMGPEAVAAALVGCKIMKEMAHLAT---EAESARSMKNA--KYEQFAMDLFSECYSNSEDRAYSLLVRKTCCWSKATVLNIATLAEAKCFFAHDGVQALLTKVWWGAMRTDTSISRLVLTFFIPPLVWTSLIKFNPEEQVSKDEGEPFAELDSLETEQALLLTDGDPVAGEGSAETAARSCSATFIRVVLRRWNRFWSAPVTVFMGNVIMYFAFLILFSYVLLLDFRPPPPYGPSA---AEIILYFWVFTLVLEEIRQSFFTDEDMSILK-KMKLYVEDNWNKCDMVAISLFVVGLSCRMAM--STYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDPRIDWVFRRALYRPYLHIFGQIPLEEIDAAKMPDDNCTTDVQEIILGTLPPCPN---IYANWLVILLLVIYLLVTNVLLLNLLIAMFSYTFQVVQENADIFWKFQRYNLIVEYHSRPALAPPFIIISH 1010
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Zebrafish
Match: trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:ZFIN;Acc:ZDB-GENE-060503-736]) HSP 1 Score: 240.736 bits (613), Expect = 2.460e-64 Identity = 273/1050 (26.00%), Postives = 483/1050 (46.00%), Query Frame = 3
Query: 318 KFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVI-LDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF---------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPE--EDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRT------LKLCIRFNCSNIADKIVFS-DPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDI--------IAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIIT--IPFSLF--LMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLL-------DENAKAPPLKSEEITFIKAM----SIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF--DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVA-------------------GPCNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
+ G I F+G KF+R D +Y+++T W + P +++++ GG + + + ++GL+ + W++ SGL GI K + +A+ + K +V IG++ W ++N L L+AK + E+ G V LD + F+ D+ K+ E +K + Q G+ ++ +L G R L YK I++ +P +++ GSG VA+++ +M + IV E L I T P+ E+ +T L++ + + ++D + + D IL+A++ + LKL + +N +IA +FS D ++ LE E+ + +L ++KP+FV LFV+N ++ F+ L+ELY SEK LL L ++ + +L +K S N + GD ++K+ + L++ + K ER F L + D + W +DLFLWA+L R +++ W + + +AL I+K+MA L + R + +A KY+ A + ++ Y+ S+ + Y+LLVR W+ T L IA F H ++ TKVW G + ++++T IP ++ L+K + P D+ LL E + +S TFI+ + + F+ AP+ F +++ Y FL++F+Y L++ +P AEI +Y +V T +EEIRQ F D++++ K K Y WNK D V I +F+ + R ++ + + R + ++ +F +R + + ++K +GPKII++ M++D+ FFL +++I YG+ ++L +PN +F+ +Y P+ FG++ LE D A PC I ++ V++ ++LL+TNVLL+NLLIAMF YTF +QE+++ W F R L+ E++ +P PP I H
Sbjct: 65 RLGDIDFTGVSRTRG----KFVRVTSSTDP----AEIYQILTKQ--WGLAPPHLVVALMGG-DEVAQLKPWLRDTLRKGLVKAAQSTGAWILTSGLRFGITKNLGQAVRDHSLASTSPKVRVVAIGIAPWNMIQNRDLL---LSAKPDHPATYPTEDLP---YGAVYSLDCNHSHFILVDE-DPKRPGATGEMRVKMLKHISLQRTGYGGTGSIEIPVLCLLVHGEPRILQKMYKNIQNSIPWLILAGSGGVADILVTLMDRGCWDAD-----IVQE----LLINTFPDGLHSTEITSWTK-LIQRILDHGHLLTVHDP-EQDSELDTVILKALVKACKSQSQEAQDFLDELKLAVAWNRVDIAKSEIFSGDVQWSAQDLE---EVMMEALVNDKPDFVRLFVDNGVNIKQFLTYGRLQELY--CSVSEKNLLHTLL--LKKNQERQAQLARKRMSGNPNN--ELGDRKFRFTFHEVSKVLKDFLDDTCKGFYQKLPAERMGKGRLFHSQKNLPDMDRRC-EHPW--RDLFLWAILQNRQEMANYFWAMGPEAVAAALVGCKIMKEMAHLAT---EAESARSMKNA--KYEQFAMDLFSECYSNSEDRAYSLLVRKTCCWSKATVLNIATLAEAKCFFAHDGVQALLTKVWWGAMRTDTSISRLVLTFFIPPLVWTSLIKFNPEEQVSKDEGEPFAELDSLETEQALLLTDGDPVAGEGSAETAARSCSATFIRVVLRRWNRFWSAPVTVFMGNVIMYFAFLILFSYVLLLDFRPPPPYGPSA---AEIILYFWVFTLVLEEIRQSFFTDEDMSILK-KMKLYVEDNWNKCDMVAISLFVVGLSCRMAM--STYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDPRIDWVFRRALYRPYLHIFGQIPLEEIDAAKMPDDNCTTDVQEIILGTLPPCPN---IYANWLVILLLVIYLLVTNVLLLNLLIAMFSYTFQVVQENADIFWKFQRYNLIVEYHSRPALAPPFIIISH 1059
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Zebrafish
Match: hrc (histidine rich calcium binding protein [Source:ZFIN;Acc:ZDB-GENE-041008-189]) HSP 1 Score: 240.736 bits (613), Expect = 2.709e-64 Identity = 274/1126 (24.33%), Postives = 511/1126 (45.38%), Query Frame = 3
Query: 159 FINKKFNTRTCYKYKEKS---KDICHCNRHLNHHTN-------KSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIK-DQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVM------GLPSKNYKESIEFIV-LENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDM-MDANMSFDKKILQAMIVGADKSMKRT-------LKLCIRFNCSNIADKIVFS---DPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQY-SQL-FDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITI-----PFSLFL-----------MKLMIMP-------------SF-PRKGKNPKDVPDAKNFHNKHLLDENAKAPP--LKSEEITFIKA-MSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXR-FSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAG----PCNGTDCIVSSGT-----------VLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
+I K F R C + E S C C + H + + +W S +T+ +G ++F G + H F+R D V++LM +W + P +++S+ GG + + + + +QGL+ + W+I GL GI + V EA+ + I ++V IG++ WG V+N Q+L NL + + N S D LD + FL DDGT + E+ F E+++ +Q G ++ +L G L ++K+ P +V+ GSG +AN++S+++ +P + +E I+ L ++ ++ + + ++ + ++ +Y N K I IY+ + F+ +L+ ++ + +++ L+L + +N +IA +F+ D KY+EL + +L++NKP+FV L +++ ++ +++ L++LY D+ C LL LH + + N + S L++ ++ L G + + Y ++L + R + + + + K W LF+WA+L R+++++ W + + +AL +L +++ + + + + + + K++ +A + Y S +Y LL+R W TCL++AI + F +H +S +++W GD+ P W+I++ I +S F+ +M P SF K +N + D++N AK P +K ++ +F+ + F+ AP+ F +LL Y +FL ++AY LV+ KP +E +Y +V T +EI++ F Y WNKFD + I +FI + R FS F + R + + +F +R + + ++K +GPKII++ M++ FFL ++++I YG+ ++L Y +F+ ++Y P+ FG++ +E D C +++ G V+I +FLL+TN+LLINLLIA F YTF ++QE S+K W F R L+ E++ +P PP IF H
Sbjct: 22 WIPKFFKKRLCTTFVEDSFSYGGRCQCGAMRDDHRSMALGDNFSTAVVSQWLSSQHTSEQPTDAYGDLEFDG---IGRRH-SYFLRLSSTTDP----ARVFDLM--KEHWKLQQPNLVVSVVGG-EGRSVVKSWVRDVLRQGLVKAAQSTGAWIITGGLRQGISRCVGEAVKDNAAAVSSITLNKVLPIGIAPWGLVENRQQL-VNLEGSFPARYMVR--NISPDS---CSLDNNHKAFLLVDDGTSGRKGGELAFRACLEDYISRQRPGNASIDIPVLNMLIAGDTSMLEFLEMSLKNSTPCLVLAGSGGLANLVSDIVENVQSAAMPGASEEEDASPIMELREQLAAKVKKYFPAENDTDKLVDKVLSIYQN-KDIISIYNAKQEGAEDFEIVMLKVLVQASKRNVSENTNSYADELRLAVTWNRVDIAKSELFNGNIDWKYEEL-----VDSMTDALENNKPQFVRLLIDSGLNILSYLTYGRLEKLYNSISDT--CLAKTLL--LHHLDERMHESNVQIYSIS---LYEVSQLLTDLLGEVCHPFYWTELKLEASSTRRKSMKKACRILMGSCKYRDEMCKHPWFC--LFIWAVLQNRSEMAIFCWEMCDESVLTALAGCKLLLELSKQEI---ETEAKLSMKELALKFERMAHDVFGTCYLSKASHSYKLLIRKSKLWGDATCLEMAIAADAQIFFSHDGVQSLLSQIWWGDIERGTPLWRILLVIICPPVCYSNFIEYRKTDQAEKEKSVMAPPCSEIDRQYEETVFSFNDNKHQNEAEHKDSENIR------RTAKGAPAFIKPKKSSFVVSRWKQFWYAPVTSFIGNLLMYFLFLFLYAYVLLVDFKPPPPDGPAV---SEYVLYFWVFTLVCQEIQEAFIAGNKKFPQTLFLYAQDVWNKFDVLAISLFITGLCCRMFSW---SFNMGRGILCVDYMVFTLRLIYIFAIHKELGPKIIILGKMIKHAFFFLFFLLVWLIAYGVANQALLYQYDPSPARVFRRVLYRPYLHIFGDIPVEEIDTGKHWERDCTDNLTLINEGIEPCRDTSHNWLVVILLVIFLLVTNILLINLLIATFSYTFTKVQEHSDKYWKFQRYNLIVEYHSRPTLAPPFIIFSH 1100
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Xenopus
Match: shc2 (SHC (Src homology 2 domain containing) transforming protein 2 [Source:Xenbase;Acc:XB-GENE-6073771]) HSP 1 Score: 298.13 bits (762), Expect = 2.757e-83 Identity = 292/1117 (26.14%), Postives = 499/1117 (44.67%), Query Frame = 3
Query: 150 IQEFINKKFNTRTCYKYKEKSKD-----ICHCNRHLNHHTN-------KSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF---------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTN----YLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRT------LKLCIRFNCSNIADKIVFSDPKYDELGLEV--IQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAH---KFSWSTQ---DLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIIT-----------IPFSLFLMKLMIMPSF-PRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEE-ITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELK---PIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDV-------------------AGPCNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
+Q +I K F +TC + E +KD +C C + +H + + W+ + +TT + +G ++F G +H KFIR + D SVY L+T + W IP P +++S+ GG + + + K ++GL+ + W++ G+ GI K V EA+ + + + +V +G++ WG V N Q L +N K + +N + LD Y FL DDGT Q E F + E + +Q G ++ +L G + L Y A K +P +++ GSG VA+ ++E+ LE I L+ G E+ F N +VE + + +Y D F+ IL+A++ K LKL + +N +IA +F + E+ + + + +L +NKP+FV LFV+N ++ +++ L+ELY D +T Y L K + ++ D +++ + N ++ +L++ I RD L D F ++ + S ST DLF+WA+L R +++ W + + SAL A ILK+++ + + + D + K++ LA + + Y S+++ + LLVR W G TCLQ+A + F +S T+ W G ++ P W +++T I F+ L + SF K N ++VP K K + +A +K ++ +++ F+ AP+ F +++ Y FL +F+Y L+E K P S E +Y ++ T EEIRQ F K Y +WN D + + +FI ++ R + F R + +F +R + + VNK +GPKII++R M++D+ FFL +++I YG+ L +P + +F+ + Y P+ Q FG++ E FD A PC T ++ V++ VFLL+ N+LL+NLLIAMF YTF+++Q +S+ W F R L+ E++ +P PP I H
Sbjct: 9 LQSWIPKLFKKKTCTTFIEDTKDSSPTKLCQCGALMINHVSVAMEDNFGAAMVSTWNSAEHTTEEPTDAYGDVEFVG---AGRKH-SKFIRLSNDTDP----ASVYSLITYN--WKIPPPNLVVSVVGGDGDFK-MKTWLKDILRKGLVKAAQSTGAWIMTGGMQVGIGKYVGEAVRDHATANSNSRTKVVAMGIAPWGIVHNRQSL---VNPKGSFPATYYMDNV---DGPTYSLDNNYSVFLLADDGTHGQMGGETSFRFRLEEHISRQKTGAGGKGSIEIPVLCMLIAGESKMLGRVYNATKSPIPCLLVAGSGGVADCLAEI----------------LEESIALESIRGLIEEKLKHYFPNENLTKMVERIVENRDLVTVYSDADGIEDFETVILKALVKACKKHSSDAVEYLDELKLAVAWNREDIAKTELF----HGEILWKATDLDDTMTDALINNKPKFVKLFVDNGLNIVDYLTYGRLEELYSSVLD---------------NTLLYQLLKSKHDEHRNSKTKDHHELLF-MESNGKGREF-KLYEVSKILRDLLGDVCTTFYTHVLGNMKGSVNKRNSGSTSPWIDLFIWAILQNRDEMATYFWEMGSEAVTSALAAMKILKELSRM---ESEAEESLAMRDLAAKFEQLAIGVFNECYRNSENRAFKLLVRRSVIWGGATCLQLAYEADARNFFAQDGVQSMLTENWWGQMAQNTPVWAMVLTFFCPPLIYTDLITFNRTLSSEELYFSFREEKDDNAEEVPLKKMSVKKSKTKKAPEAEIIKEKQRPRWMQRWKQFWSAPVTAFFGNVVMYFAFLFLFSYVLLLEFKMPPPDGPANS------EFILYFWIFTMVCEEIRQSFFVGTMPVAQKVKQYLQDSWNHVDIIALCLFIIGLICR--MFNESFEAGRTILCFDFMVFTLRLIHIFAVNKQLGPKIIIVRKMMKDVFFFLFFLGVWLIAYGVTTEGLLHPTDMRLSWIFRRVFYRPYLQIFGQIPQEEFDASKIASSNCTNDPIAIMLEEAEPCTNT---YANWLVILLLVVFLLVANILLLNLLIAMFSYTFSKVQGNSDIYWKFQRYNLIVEYHNRPALAPPFIIISH 1057
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Xenopus
Match: shc2 (SHC (Src homology 2 domain containing) transforming protein 2 [Source:Xenbase;Acc:XB-GENE-6073771]) HSP 1 Score: 296.975 bits (759), Expect = 6.837e-83 Identity = 287/1103 (26.02%), Postives = 491/1103 (44.51%), Query Frame = 3
Query: 150 IQEFINKKFNTRTCYKYKEKSKD-----ICHCNRHLNHHTN-------KSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF---------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTN----YLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRT------LKLCIRFNCSNIADKIVFSDPKYDELGLEV--IQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQ---DLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITI--PFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELK---PIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDV-------------------AGPCNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
+Q +I K F +TC + E +KD +C C + +H + + W+ + +TT + +G ++F G +H KFIR + D SVY L+T + W IP P +++S+ GG + + + K ++GL+ + W++ G+ GI K V EA+ + + + +V +G++ WG V N Q L +N K + +N + LD Y FL DDGT Q E F + E + +Q G ++ +L G + L Y A K +P +++ GSG VA+ ++E+ LE I L+ G E+ F N +VE + + +Y D F+ IL+A++ K LKL + +N +IA +F + E+ + + + +L +NKP+FV LFV+N ++ +++ L+ELY D +T Y L K + ++ D +++ + N ++ +L++ I RD L D F ++ V+ ++ ST DLF+WA+L R +++ W + + SAL A ILK+++ + + + D + K++ LA + + Y S+++ + LLVR W G TCLQ+A + F +S T+ W G ++ P W +++T P L L+ S + G P+A+ K + +++ F+ AP+ F +++ Y FL +F+Y L+E K P S E +Y ++ T EEIRQ F K Y +WN D + + +FI ++ R F R + +F +R + + VNK +GPKII++R M++D+ FFL +++I YG+ L +P + +F+ + Y P+ Q FG++ E FD A PC T ++ V++ VFLL+ N+LL+NLLIAMF YTF+++Q +S+ W F R L+ E++ +P PP I H
Sbjct: 9 LQSWIPKLFKKKTCTTFIEDTKDSSPTKLCQCGALMINHVSVAMEDNFGAAMVSTWNSAEHTTEEPTDAYGDVEFVG---AGRKH-SKFIRLSNDTDP----ASVYSLITYN--WKIPPPNLVVSVVGGDGDFK-MKTWLKDILRKGLVKAAQSTGAWIMTGGMQVGIGKYVGEAVRDHATANSNSRTKVVAMGIAPWGIVHNRQSL---VNPKGSFPATYYMDNV---DGPTYSLDNNYSVFLLADDGTHGQMGGETSFRFRLEEHISRQKTGAGGKGSIEIPVLCMLIAGESKMLGRVYNATKSPIPCLLVAGSGGVADCLAEI----------------LEESIALESIRGLIEEKLKHYFPNENLTKMVERIVENRDLVTVYSDADGIEDFETVILKALVKACKKHSSDAVEYLDELKLAVAWNREDIAKTELF----HGEILWKATDLDDTMTDALINNKPKFVKLFVDNGLNIVDYLTYGRLEELYSSVLD---------------NTLLYQLLKSKHDEHRNSKTKDHHELLF-MESNGKGREF-KLYEVSKILRDLLGDVCTTF-YTHQIAVEKYQPRKSTSPWIDLFIWAILQNRDEMATYFWEMGSEAVTSALAAMKILKELSRM---ESEAEESLAMRDLAAKFEQLAIGVFNECYRNSENRAFKLLVRRSVIWGGATCLQLAYEADARNFFAQDGVQSMLTENWWGQMAQNTPVWAMVLTFFCP-PLIYTDLITFNSVEQNG-----APEAEIIKEK--------------QRPRWMQRWKQFWSAPVTAFFGNVVMYFAFLFLFSYVLLLEFKMPPPDGPANS------EFILYFWIFTMVCEEIRQSFFVGTMPVAQKVKQYLQDSWNHVDIIALCLFIIGLICRMF--NESFEAGRTILCFDFMVFTLRLIHIFAVNKQLGPKIIIVRKMMKDVFFFLFFLGVWLIAYGVTTEGLLHPTDMRLSWIFRRVFYRPYLQIFGQIPQEEFDASKIASSNCTNDPIAIMLEEAEPCTNT---YANWLVILLLVVFLLVANILLLNLLIAMFSYTFSKVQGNSDIYWKFQRYNLIVEYHNRPALAPPFIIISH 1022
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Xenopus
Match: shc2 (SHC (Src homology 2 domain containing) transforming protein 2 [Source:Xenbase;Acc:XB-GENE-6073771]) HSP 1 Score: 291.967 bits (746), Expect = 2.811e-81 Identity = 289/1113 (25.97%), Postives = 487/1113 (43.76%), Query Frame = 3
Query: 150 IQEFINKKFNTRTCYKYKEKSKD-----ICHCNRHLNHHTN-------KSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF---------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTN----YLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRT------LKLCIRFNCSNIADKIVFSDPKYDELGLEV--IQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQ---DLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITI--PFSLFLMKLMIMP------SFPRKGKNPKDVPDAKNFHNK----HLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELK---PIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDV-------------------AGPCNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
+Q +I K F +TC + E +KD +C C + +H + + W+ + +TT + +G ++F G +H KFIR + D SVY L+T + W IP P +++S+ GG + + + K ++GL+ + W++ G+ GI K V EA+ + + + +V +G++ WG V N Q L +N K + +N + LD Y FL DDGT Q E F + E + +Q G ++ +L G + L Y A K +P +++ GSG VA+ ++E+ LE I L+ G E+ F N +VE + + +Y D F+ IL+A++ K LKL + +N +IA +F + E+ + + + +L +NKP+FV LFV+N ++ +++ L+ELY D +T Y L K + ++ D +++ S + +L++ I RD L D F ++ V+ ++ ST DLF+WA+L R +++ W + + SAL A ILK+++ + + + D + K++ LA + + Y S+++ + LLVR W G TCLQ+A + F +S T+ W G ++ P W +++T P ++ + P S P V N + LL E K F+ AP+ F +++ Y FL +F+Y L+E K P S E +Y ++ T EEIRQ F K Y +WN D + + +FI ++ R F R + +F +R + + VNK +GPKII++R M++D+ FFL +++I YG+ L +P + +F+ + Y P+ Q FG++ E FD A PC T ++ V++ VFLL+ N+LL+NLLIAMF YTF+++Q +S+ W F R L+ E++ +P PP I H
Sbjct: 9 LQSWIPKLFKKKTCTTFIEDTKDSSPTKLCQCGALMINHVSVAMEDNFGAAMVSTWNSAEHTTEEPTDAYGDVEFVG---AGRKH-SKFIRLSNDTDP----ASVYSLITYN--WKIPPPNLVVSVVGGDGDFK-MKTWLKDILRKGLVKAAQSTGAWIMTGGMQVGIGKYVGEAVRDHATANSNSRTKVVAMGIAPWGIVHNRQSL---VNPKGSFPATYYMDNV---DGPTYSLDNNYSVFLLADDGTHGQMGGETSFRFRLEEHISRQKTGAGGKGSIEIPVLCMLIAGESKMLGRVYNATKSPIPCLLVAGSGGVADCLAEI----------------LEESIALESIRGLIEEKLKHYFPNENLTKMVERIVENRDLVTVYSDADGIEDFETVILKALVKACKKHSSDAVEYLDELKLAVAWNREDIAKTELF----HGEILWKATDLDDTMTDALINNKPKFVKLFVDNGLNIVDYLTYGRLEELYSSVLD---------------NTLLYQLLKSKHDEHRNSKTKDHHELLFMESNG--KGREFKLYEVSKILRDLLGDVCTTF-YTHQIAVEKYQPRKSTSPWIDLFIWAILQNRDEMATYFWEMGSEAVTSALAAMKILKELSRM---ESEAEESLAMRDLAAKFEQLAIGVFNECYRNSENRAFKLLVRRSVIWGGATCLQLAYEADARNFFAQDGVQSMLTENWWGQMAQNTPVWAMVLTFFCPPLIYTDLITFKPNNYMISSHLSIDPTPHTVTINSNLLGREGCCRLLPERWKQ----------------FWSAPVTAFFGNVVMYFAFLFLFSYVLLLEFKMPPPDGPANS------EFILYFWIFTMVCEEIRQSFFVGTMPVAQKVKQYLQDSWNHVDIIALCLFIIGLICRMF--NESFEAGRTILCFDFMVFTLRLIHIFAVNKQLGPKIIIVRKMMKDVFFFLFFLGVWLIAYGVTTEGLLHPTDMRLSWIFRRVFYRPYLQIFGQIPQEEFDASKIASSNCTNDPIAIMLEEAEPCTNT---YANWLVILLLVVFLLVANILLLNLLIAMFSYTFSKVQGNSDIYWKFQRYNLIVEYHNRPALAPPFIIISH 1036
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Xenopus
Match: shc2 (SHC (Src homology 2 domain containing) transforming protein 2 [Source:Xenbase;Acc:XB-GENE-6073771]) HSP 1 Score: 280.026 bits (715), Expect = 9.310e-78 Identity = 269/1008 (26.69%), Postives = 463/1008 (45.93%), Query Frame = 3
Query: 423 SVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADG----FLVQILFEGGRRALL---NAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTN----YLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRT------LKLCIRFNCSNIADKIVFSDPKYDELGLEV--IQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELL---CDLHRDTKS---YFKLNKKSNSTEQN-RLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELK---PIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLE 3359
SVY L+T + W IP P +++S+ GG + + + K ++GL+ + W++ G+ GI K V EA+ + + + +V +G++ WG V N Q L +N K + +N + LD Y FL DDGT Q E F + E + +Q G F L + A+L Y A K +P +++ GSG VA+ ++E+ LE I L+ G E+ F N +VE + + +Y D F+ IL+A++ K LKL + +N +IA +F + E+ + + + +L +NKP+FV LFV+N ++ +++ L+ELY D+ +LL D HR++K+ + L +SN + +L++ I+ L G++ Y+ + + S + S K + DLF+WA+L R +++ W + + SAL A ILK+++ + + + D + K++ LA + + Y S+++ + LLVR W G TCLQ+A + F +S T+ W G ++ P W +++T F L+ K + ++ ++ LD + K + +++ F+ AP+ F +++ Y FL +F+Y L+E K P S E +Y ++ T EEIRQ F K Y +WN D + + +FI ++ R + F R + +F +R + + VNK +GPKII++R M++D+ FFL +++I YG+ L +P + +F+ + Y P+ Q FG++ E FD A PC T ++ V++ VFLL+ N+LL+NLLIAMF YTF+++Q +S+ W F R L+ E++ +P PP I H I+ K + K+ ++ + MLE
Sbjct: 11 SVYSLITYN--WKIPPPNLVVSVVGGDGDFK-MKTWLKDILRKGLVKAAQSTGAWIMTGGMQVGIGKYVGEAVRDHATANSNSRTKVVAMGIAPWGIVHNRQSL---VNPKGSFPATYYMDNV---DGPTYSLDNNYSVFLLADDGTHGQMGGETSFRFRLEEHISRQKTGAGGRFDYGPLNDNRNVAILYFQRVYNATKSPIPCLLVAGSGGVADCLAEI----------------LEESIALESIRGLIEEKLKHYFPNENLTKMVERIVENRDLVTVYSDADGIEDFETVILKALVKACKKHSSDAVEYLDELKLAVAWNREDIAKTELF----HGEILWKATDLDDTMTDALINNKPKFVKLFVDNGLNIVDYLTYGRLEELYSSVLDN--TLLYQLLKSKHDEHRNSKTKDHHELLFMESNGKGREFKLYEVSKILRDLLGDVCTTFYTHVLGN-------MKGSVNK----RNSGYQPRKSTSPWIDLFIWAILQNRDEMATYFWEMGSEAVTSALAAMKILKELSRM---ESEAEESLAMRDLAAKFEQLAIGVFNECYRNSENRAFKLLVRRSVIWGGATCLQLAYEADARNFFAQDGVQSMLTENWWGQMAQNTPVWAMVLT----FFCPPLIYTDLITFKSIDHENGIESAQRMEMDSLDTDIKTTV--KQRPRWMQRWKQFWSAPVTAFFGNVVMYFAFLFLFSYVLLLEFKMPPPDGPANS------EFILYFWIFTMVCEEIRQSFFVGTMPVAQKVKQYLQDSWNHVDIIALCLFIIGLICR--MFNESFEAGRTILCFDFMVFTLRLIHIFAVNKQLGPKIIIVRKMMKDVFFFLFFLGVWLIAYGVTTEGLLHPTDMRLSWIFRRVFYRPYLQIFGQIPQEEFDEAEPCTNT---YANWLVILLLVVFLLVANILLLNLLIAMFSYTFSKVQGNSDIYWKFQRYNLIVEYHNRPALAPPFIIISH----INTFIKRKIRKVASQKIRHFMLE 952
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Xenopus
Match: TRPM6 (transient receptor potential cation channel, subfamily M, member 6 [Source:NCBI gene;Acc:100487366]) HSP 1 Score: 279.641 bits (714), Expect = 3.847e-76 Identity = 278/1133 (24.54%), Postives = 508/1133 (44.84%), Query Frame = 3
Query: 189 CYKYKEKSKDICHCNRHLNHH-----------TNKSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQ------ADGF-LVQILFEGGRRALLNAYKAIKDK--VPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDM-MDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNR--LFDAGDIIAKLSGNLLNNQYSQ---------LFDK------------PLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMA-DLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEE----------ITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVSSGTVLISF--AVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLE-HCKPSKSLKLNNFEQFCL 3413
CY +K C C R + H + + EEWS N+T FG I F + H + K+IR D T + LM W + P ++IS++GG++N + + + K+ F +GL+ + W++ G++ G K V +A+ + H ++ +G+ WG ++N Q L IG ++V Y+ L++++ F+ DDGT +Y E++ E+F+ Q G +V ++ EGG +L ++ ++ VP+VV +G+GR A++++ + + E I+ + T + G + V Y++ + I I+D + D IL A++ G + S + L L + +N +IA K + ++ ++G +++ +L ++ +FV L +E ++ F+ L+ELY ++++ P LL L RD K +SN + R L D G +I L G + Y++ LF K L + F T + D + F + DL +WA+L R ++M W+ + + A+ A + + MA + ++ +L SK++ LA I+ A+ ++ LL L W+ TCL++A++ + F++H+ + T +WMG L +W +I + L ++M F K + VP + FH L P L+ ++ + + + FY APIVKF H + Y+ FLM+F Y LV++ P + Q W I IY+ T A+E++R+VF E K + WN D++ I +F R+ P R ++ + + + +R + F+ VN+ GP I M+ M ++ + I I ++ +G+ +++ P+ + L +DIV+ P++ FGE+ D DC G+ + F AV+L + ++++NLLI++F + + S KLW + R + + +Y KP PPPL H + +I+ C R +E ++ L+ + ++ KL++FE+ C+
Sbjct: 29 CYVMAQK----CCCGRLIGDHPGLDYGWPINPSPQEREDEEWSILNHTKPSPTDAFGTINFQ---DGDHTYHAKYIRISY----DTTLELLMHLMIKE--WQMELPKLVISVHGGIQNFK-LPSKIKQVFGKGLVKAAETTGAWILTEGINTGASKHVGDAL---KAHASQHLRKICAVGIPPWGAIENQQDL-------IGKDVVCLYQTLINPMSKLTSLNSMHSHFIMVDDGTVGKYGNEMKLRRNLEDFISLQKIHTRMGQGVPVVGLVIEGGPNVILMVWEYVRSTPPVPVVVCEGTGRAADILAFTHKHTTDTDPQLKEEILEMIQKTFNL--GHRQSNHVL----YILMECMERRASITIFDAESEEQQDIDLAILTALLKGTNMSAQDQLSLALTWNRVDIAKKHILIYGQHWKVG--SLEQAMQDALVMDRVDFVKLLIEYGVNMHRFLTIGHLEELY----NTKQGPTNLLLHHLVRDVK-------QSNPSPDYRISLIDVGLVIEYLIGGAYRSSYTRKSFRVLYNSLFRKHKMSSKLESPESTLHSQFFRTAQPCRHEVTCTEDNEPVGFIYPYNDLLVWAVLMKRQKMAMFFWQHGEEAMVKAVIACKLYRAMAHEAKQSTMVDDTSEELKKYSKEFGQLALDILENAFKMNEQMAMKLLTYQLKNWSNSTCLKLAVSSTLRPFVSHTCTQMLLTDMWMGRLKMRKHSWLKVI---LGILLPPFVLMLEFKTKAEM-SHVPQSLEFHQFSRL--YVDPPSLREDQNQKISNGLGILPITRKICEFYSAPIVKFWFHTMVYLAFLMLFTYTVLVKMDPQPSV----QEWCVI---IYIFTTAVEKVREVFVSEPGKFSQKVKVWINEYWNLTDSIAIFLFFIGFGLRWPDPPFQ-TAGRIIYCLDIIFWYVRLLDFFAVNQQAGPYITMLGKMTSNMFGIVIIMAIVLLAFGVSRKAILSPDHPPSWTLARDIVFQPYWMMFGEVYAGEIDACE--EDPDC--PPGSFITPFLQAVYLFVQYIIMVNLLISLFNNVYRVLNSVSHKLWKYNRYRYIMTYYEKPWLPPPLIFLSHIYILINRLCHHRSHSEFDPEETDMGLKLYLSDNELRKLHDFEEKCV 1100
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Mouse
Match: Trpm2 (transient receptor potential cation channel, subfamily M, member 2 [Source:MGI Symbol;Acc:MGI:1351901]) HSP 1 Score: 291.197 bits (744), Expect = 3.463e-80 Identity = 291/1101 (26.43%), Postives = 496/1101 (45.05%), Query Frame = 3
Query: 141 EDQIQEFINKKFNTRTCYKYKEKSK------DICHCNRHLNHHTNKSNSP-----EEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQA---DGFLVQI-----LFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGA-------DKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDI-------IAKLSGNLLNNQYSQLFDKP-LIERDFLTDSFEEFAM---------LYESDVDAHKFSWS-TQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIII-TIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF-DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELML----ENF--DVAGPCNGTD-----CIVSSGT----------VLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGK 3242
++ + +I + + C + E SK +C C H + P +EW + FG I F+ + K++R D +Y+LMT +W + P ++IS+ GG KN ++ K F++GL+ V + W+I G G+ K V EA+ +F + +V IGV+TWGT+ N + L + +Y E + LD+ + F+ DDGT QY E+ K E F+ +Q G ++I + EGG L Y AI + P V+++GSGRVA++I++V LP +I I + I Q + ++ E+T + ++ + + + D D ILQA++ + ++ LKL + +N +IA +F+D + + M +L NKPEFV LF+EN LKE +++D+ C L +L + KL K E+ RL A +A++ LL + L+ +P +R L+ + + LY+ F+ +DL +WA++ +L+ I+W S++ +AL + ILK+++ + L D +++ A + T+ Y K + + LLVR W TCLQ+A+ ++F++H +++ TKVW G L W+II+ + F L + +F K L A P + + F+ AP+V F +++LSY FL +FAY +V+ +P W E IY+++ + EE RQ+F D + G YF WNK D I++FI + R IP + R + S+ MF +R M + ++K++GPKII+++ M++D+ FFL + ++V+++G+ +++ N +F+ +VY + FG++ NF D P NGTD C S T + ++LL N+LL+NLLIAMF YTF ++QE ++++W F R L++E++G+
Sbjct: 55 QENLSSWIPENIKKKECVYFVESSKLSDAGKVVCACGYTHEQHLEVAIKPHTFQGKEWDPKKHVQEMPTDAFGDIVFTDL----SQKVGKYVRVSQ----DTPSSVIYQLMTQ--HWGLDVPNLLISVTGGAKNF-NMKLRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSCKEGEVITIGVATWGTIHNREGLIHPMGG-----FPAEYMLDEEGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTKLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIYNAINNGTPCVIVEGSGRVADVIAQVATLPVSEI--TISLIQQKLSIFFQEMFETFTENQIVEWTKKIQDIVRRRQLLTIFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFTDEW--QWKPADLHPMMTAALISNKPEFVRLFLENGVR---------LKEF--VTWDTLLC----LYENLEPSCLFHSKLQKV--LAEEQRLAYASATPRLHMHHVAQVLRELLGDSTQLLYPRPRYTDRPRLSMTVPHIKLNVQGVSLRSLYKRSTGHVTFTIDPVRDLLIWAVIQNHRELAGIIWAQSQDCTAAALACSKILKELSKEEEDTDSSEEMLALAD---EFEHRAIGVFTECYRKDEERAQKLLVRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLCVDNGLWRIILCMLAFPLLFTGFI-------------------SFREKRL---QALCRPAR---------VRAFFNAPVVIFHMNILSYFAFLCLFAYVLMVDFQP-------SPSWCEYLIYLWLFSLVCEETRQLFYDPDGCGLMKMASLYFSDFWNKLDVGAILLFIVGLTCRL-IPATLYP-GRIILSLDFIMFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNESRVDWIFRGVVYHSYLTIFGQIPTYIDGVNFSMDQCSP-NGTDPYKPKCPESDWTGQAPAFPEWLTVTLLCLYLLFANILLLNLLIAMFNYTFQEVQEHTDQIWKFQRHDLIEEYHGR 1074
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Mouse
Match: Trpm6 (transient receptor potential cation channel, subfamily M, member 6 [Source:MGI Symbol;Acc:MGI:2675603]) HSP 1 Score: 281.952 bits (720), Expect = 6.345e-77 Identity = 301/1216 (24.75%), Postives = 541/1216 (44.49%), Query Frame = 3
Query: 153 QEFINKKFNTRTCYKYKEKSKD---------ICH------CNRHLNHH----------TNKSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQA------DGF-LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMIS------EVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDM-MDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGN-------------LLNNQYSQ----------LFDKPLIERDFLTD-----------SFEEFAMLYES----------------------DVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMA------DLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTW-KIIITIPFSLFLMKLMI-----MPSFPRKG-------------KNPKDVPDAKNFHNKHLLDENAKAP---PLKS--EEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVSSGTVLISF--AVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFEQFCLNE 3419
+ +I F R C K+ SKD ICH C R + H + + E+WS +T FG I F + H H K+IR + D + LM WN+ P ++IS++GGL+N + IS+ K+ F QGL+ + W+I G+++G+ K V +A+ + H ++ +G+ WG ++N + L +G ++V Y+ L+ ++ F+ CDDGT Y E + E + Q G +V ++ EGG +L ++ +K+K P+VV +G+GR A++++ E G+ KE + F +++N + + + L+E + K I I+D + + D IL A++ G S+ L L + ++ +IA K + + ++ + G +++ L +L ++ +FV L +EN ++ F+ L+ELY ++++ P + L L +D K + L S+ + L D G +I L G L NN Y + L L +R L + F A Y+S + +A F + DL +WA+L R +++M W+ + A+ A+I+ + MA ++V ++ +L + S+++ LA ++ +A+ +++ LL L W+ TCL++A++G + F++HS + T +WMG L +W KIII+I ++ L M P+ N K+ K++ + DE P L++ + + + + + FY AP VKF + ++Y+ FLM+F Y LVE++P + E + IY+ T AIE++R++ E + K K + WN + V I +F R+ P R ++ I + + R M F+ VN+ GP + MI M ++ + + I I ++++G+ +++ P + L +DIV+ P++ +GE+ + DV N T C G+ L F AV+L + ++++NLLIA F + I+ S KLW + R + + ++ KP PPP + H ++ C P+ E + L L K KL++FE+ C+ +
Sbjct: 5 KSWIEGVFYKRECNKFIPSSKDPHRCTPGCQICHNLVRCYCGRLIEEHHGLDRAWNLSVTEGHGDEQWSVEKHTVKSPTDTFGTINFQ---DGEHIHHSKYIRTSWDTKSD----HLLHLMLKE--WNMELPKLVISVHGGLQNFK-ISSKLKETFSQGLVKAAETTGAWIITEGINSGVSKHVGDAL---KAHSSKSLRKIWTVGIPPWGVIENQREL-------VGKDVVCMYQTLGNPLSKLTTLNCMHSHFILCDDGTVGMYGNEEKLRRNLEKHLSMQKIHTCSRQGVPVVGLVMEGGPNVILWVWETVKNKEPVVVCEGTGRAADLLAFTYKHLEDGGILRPQVKEEL-FCLIQNMFNFSL-------RQSKHLFQILMECMVH-KDSITIFDADSEEHQDLDLAILTALLKGTSLSISEQLNLAMAWDRMDIAKKHILTYGQHWKPG--ALEQAMLDALVMDRVDFVKLLIENGVNLHRFLTIPRLEELY----NTKQGPTNKFLRHLVQDVKQHTLL-----SSYRITLIDIGLVIEYLIGGAYRSSYTRKSFRILYNNLYRKHKSVSSFAQGLSQHSLHQRHSLRNRKESSESTLHSQFFRTAQPYKSKEKPEDSQKSKKKSKERQSLSEEPEAAGFIYPYNDLLVWAVLMKRQNMAMFFWQHGEEATVKAVIASILYRAMAREAKESNMV-----DDTSEELKNYSEQFGQLALDVLEKAFKQNEPMAMKLLTYELKNWSNSTCLKLAVSGGLRPFVSHSCTQMLLTDMWMGRLKMRKNSWLKIIISILLPPMILTLEFKSKAEMSHVPQSQDFQFTWNYSDQGLSNTKESACVKDYDLERGPDEKPDEPLHLDLRNVPQSLPWTRRVYEFYSAPFVKFWFYTMAYLAFLMLFTYTVLVEMQPQPSVH-------EWLVIIYIFTNAIEKVREICISEPSKFKQKVKMWLSEYWNLMETVAIGLFAVGFGLRWGHPPLQ-TAGRLIYCIDIIFWFSRLMDFFAVNQHAGPYVTMIAKMAANMFYIVIIMAIVLLSFGVARKAILSPKEPPSWRLARDIVFEPYWMMYGEVYASDIDVCS--NETSC--PPGSFLTPFLQAVYLFVQYIIMVNLLIACFNNIYLDIKSISNKLWKYNRYRYIMTYHQKPWLPPPFILLNHLCLLLRGLCCRPAPQDQEEGDGGLKLYLTKDDLK-KLHDFEEQCVEK 1162
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101]) HSP 1 Score: 278.87 bits (712), Expect = 2.072e-76 Identity = 306/1216 (25.16%), Postives = 538/1216 (44.24%), Query Frame = 3
Query: 153 QEFINKKFNTRTCYKYKEKSKDI--CHCNRHLNHHTNKSNS-------------------PEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIR--FDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQ------ADGF-LVQILFEGGRRALLNAYKAIKDK--VPLVVIKGSGRVANMI------SEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMM--DANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKS---------YFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQ---------LF---------------DKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMA------DLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPT-WKIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHL--------------LDE------------NAKAPPLKSEE--------ITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTD------------CIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSL-KLNNFEQFCLNE 3419
+ +I + F R C +KD C C R + H + S E+WS S +T L FG I+F G H + ++R FD + D + LMT W + P ++IS++GGL+N E + K+ F +GLI W+ G++ G+ + V +A+ + H + ++ IG++ WG V+N + L IG ++V Y+ S +L++++ F+ D+GT +Y EV+ + E + Q G +V ++ EGG + + ++D VP+VV GSGR ++++ SE GL +++ ++ + + ++ T + +++ M C KK+++ M + + D IL A++ GA+ S L L + +N +IA +F + +G +++ L +L ++ +FV L +EN + F+ + L+ELY ++ P + L L RD K YFK N + + L D G +I L G Y++ LF D PL T EE + D + + F + +L +WA+L R +++ W+ + + AL A + K MA D+V +++ ++L S+ + LA ++ Q+Y + + LL L W+ TCLQ+A+ +F+ H+ + T +WMG L + K+I+ I ++ L + KN D+P HL DE N ++ K EE I + + FY APIVKF + L+YI +LM+F Y LV++ E Q W I Y+ T IE++R++ E K + WN D + I++F ++ R Q R ++ +++ + IR + + VNK +GP ++MI M+ D+++F+ I ++ ++++G+ +++ +PN E + L K+I Y P++ +GE+ + D PC + C + V A +LL+ N+LL+NLLIA+F TF +++ S ++W F R QL+ F+ +P+ PPPL IF H I C + E + L+ L K+++FE+ C+ E
Sbjct: 62 KSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGG---HSNKAMYVRVSFDTKPDL------LLHLMTKE--WQLELPKLLISVHGGLQNFE-LQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKD---HASKSRGKICTIGIAPWGIVENQEDL-------IGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL-LVTIQKTFTY---------TRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVG--SLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELY----NTRHGP-SNTLYHLVRDVKKREYPGFGWIYFKGNLPPDY--RISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMV-----DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL--------EFKNKDDMPYMTQAQEIHLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKM----ERWPSTQEWIVIS---YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQ-DQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQID--PPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHVCCRWRKHESDQDERDYGLKLFITDDELKKVHDFEEQCIEE 1213
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101]) HSP 1 Score: 279.256 bits (713), Expect = 3.312e-76 Identity = 309/1219 (25.35%), Postives = 542/1219 (44.46%), Query Frame = 3
Query: 105 NTKSEITIKNGFEDQI----QEFINKKFNTRTCYKYKEKSKDI--CHCNRHLNHHTNKSNS-------------------PEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIR--FDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQ------ADGF-LVQILFEGGRRALLNAYKAIKD--KVPLVVIKGSGRVANMI------SEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMM--DANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNR--LFDAGDIIAKLSGNLLNNQYSQ---------LF-----DKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMA------DLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTW-KIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHL--------------LDE------------NAKAPPLKSEE--------ITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTD------------CIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSL-KLNNFEQFCLNE 3419
++K T ++G Q + +I + F R C +KD C C R + H + S E+WS S +T L FG I+F G H + ++R FD + D + LMT W + P ++IS++GGL+N E + K+ F +GLI W+ G++ G+ + V +A+ + H + ++ IG++ WG V+N + L IG ++V Y+ S +L++++ F+ D+GT +Y EV+ + E + Q G +V ++ EGG + + ++D VP+VV GSGR ++++ SE GL +++ ++ + + ++ T + +++ M C KK+++ M + + D IL A++ GA+ S L L + +N +IA +F + +G +++ L +L ++ +FV L +EN + F+ + L+ELY ++ P + L L RD KK N R L D G +I L G Y++ LF D PL T EE + D + + F + +L +WA+L R +++ W+ + + AL A + K MA D+V +++ ++L S+ + LA ++ Q+Y + + LL L W+ TCLQ+A+ +F+ H+ + T +WMG L + K+I+ I ++ L KN D+P HL DE N ++ K EE I + + FY APIVKF + L+YI +LM+F Y LV++ E Q W I Y+ T IE++R++ E K + WN D + I++F ++ R Q R ++ +++ + IR + + VNK +GP ++MI M+ D+++F+ I ++ ++++G+ +++ +PN E + L K+I Y P++ +GE+ + D PC + C + V A +LL+ N+LL+NLLIA+F TF +++ S ++W F R QL+ F+ +P+ PPPL IF H I C + E + L+ L K+++FE+ C+ E
Sbjct: 44 SSKQGSTKRSGLPAQQTPAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGG---HSNKAMYVRVSFDTKPDL------LLHLMTKE--WQLELPKLLISVHGGLQNFE-LQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKD---HASKSRGKICTIGIAPWGIVENQEDL-------IGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL-LVTIQKTFTY---------TRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVG--SLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELY----NTRHGP-SNTLYHLVRDV-------KKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMV-----DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEF--------KNKDDMPYMTQAQEIHLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKM----ERWPSTQEWIVIS---YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQ-DQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQID--PPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHVCCRWRKHESDQDERDYGLKLFITDDELKKVHDFEEQCIEE 1193
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101]) HSP 1 Score: 279.256 bits (713), Expect = 3.729e-76 Identity = 310/1226 (25.29%), Postives = 545/1226 (44.45%), Query Frame = 3
Query: 105 NTKSEITIKNGFEDQI----QEFINKKFNTRTCYKYKEKSKDI--CHCNRHLNHHTNKSNS-------------------PEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIR--FDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQ------ADGF-LVQILFEGGRRALLNAYKAIKDK--VPLVVIKGSGRVANMI------SEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMM--DANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKS---------YFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQ---------LF-----DKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMA------DLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTW-KIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHL--------------LDE------------NAKAPPLKSEE--------ITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTD------------CIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSL-KLNNFEQFCLNE 3419
++K T ++G Q + +I + F R C +KD C C R + H + S E+WS S +T L FG I+F G H + ++R FD + D + LMT W + P ++IS++GGL+N E + K+ F +GLI W+ G++ G+ + V +A+ + H + ++ IG++ WG V+N + L IG ++V Y+ S +L++++ F+ D+GT +Y EV+ + E + Q G +V ++ EGG + + ++D VP+VV GSGR ++++ SE GL +++ ++ + + ++ T + +++ M C KK+++ M + + D IL A++ GA+ S L L + +N +IA +F + +G +++ L +L ++ +FV L +EN + F+ + L+ELY ++ P + L L RD K YFK N + + L D G +I L G Y++ LF D PL T EE + D + + F + +L +WA+L R +++ W+ + + AL A + K MA D+V +++ ++L S+ + LA ++ Q+Y + + LL L W+ TCLQ+A+ +F+ H+ + T +WMG L + K+I+ I ++ L KN D+P HL DE N ++ K EE I + + FY APIVKF + L+YI +LM+F Y LV++ E Q W I Y+ T IE++R++ E K + WN D + I++F ++ R Q R ++ +++ + IR + + VNK +GP ++MI M+ D+++F+ I ++ ++++G+ +++ +PN E + L K+I Y P++ +GE+ + D PC + C + V A +LL+ N+LL+NLLIA+F TF +++ S ++W F R QL+ F+ +P+ PPPL IF H I C + E + L+ L K+++FE+ C+ E
Sbjct: 44 SSKQGSTKRSGLPAQQTPAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGG---HSNKAMYVRVSFDTKPDL------LLHLMTKE--WQLELPKLLISVHGGLQNFE-LQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKD---HASKSRGKICTIGIAPWGIVENQEDL-------IGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL-LVTIQKTFTY---------TRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVG--SLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELY----NTRHGP-SNTLYHLVRDVKKREYPGFGWIYFKGNLPPDY--RISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMV-----DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEF--------KNKDDMPYMTQAQEIHLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKM----ERWPSTQEWIVIS---YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQ-DQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQID--PPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHVCCRWRKHESDQDERDYGLKLFITDDELKKVHDFEEQCIEE 1205
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. UniProt/SwissProt
Match: sp|A7T1N0|TMP2L_NEMVE (Transient receptor potential cation channel subfamily M member-like 2 OS=Nematostella vectensis OX=45351 GN=TRPM2 PE=1 SV=1) HSP 1 Score: 327.405 bits (838), Expect = 3.756e-91 Identity = 306/1201 (25.48%), Postives = 544/1201 (45.30%), Query Frame = 3
Query: 132 NGFEDQIQEFINKKFNTRTCYKYKEKSKDI--CHCNRHLNHHTNKS----NSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISE--FRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEV-------EFLLKFENFVKKQADGF---LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEE--DAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMS--FDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELY-EISFDSEKCPCAELLCDLHRDTKSYFKLN---KKSNSTEQNRLFD---AGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQ---------------DLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDN---NLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLM-IMP---------------------SFPRKGKNPKDVPDAKNFHNKHLL----DENAKAPPLKSEE-------------------------ITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYC---NLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPN----SEFNT-LLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVSSGTVL--ISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAF---RIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFE 3401
N + +I + F+ R C ++ KS D+ C C R H+ ++ EEW+ ++ TT +G I F GY + ++R D DA V LM WN+ P ++IS+ GG K+ + ++ F++GLI K W+I G + G+ K V EA+ E F + QV++IG++TWG V L N K ++ E T + +LD + F DDGTE +Y E+ E ++K + + +A +V ++ EGG + Y+ IK KVP VVI GSGR A+++ K + V++ + ++ E A+ + T +++ +K I +Y + D +S D IL+A++ S L L + +N ++A +F++ + + E + L +L D+K A EL+ + + ++LC L+ + + +K Q + D G++I +L G++ + Y +D F E A E V ++ S D+FLWA+L R +L+ +LW + + +AL A+ +LK+MA + DN ++ L D ++ +++ A ++ + +N++++ + TLLVR L ++ +T L++A++ +F+ H++C+ T++WMG ++ WK+++ + + + ++ +P S + K D P + +K DE A+ EE + F + FY AP KF +++ Y+ F+ ++AY N P + + I EI +Y +V T IEEIRQ+ + K K YF TWN D + +FI +++ RF F R + S+ + F++RS+Q + VN+ +GPK++MI+ M++D+ F+ I +F I YGI ++ +P+ + NT + +V P++Q +GEL L+ P + + G L + A++++ TN+LL+NLLIA+F YTF ++QEDS+K+W F R LVQE++ +P+F PPL + H R + C+ P + M P++ +++N+E
Sbjct: 26 NQLSQSKKSWIARNFSRRECIRFVPKSHDVSRCKCGRPRERHSQQALESGQGSEEWNVASCTTKHPTNAYGEIDFEGYGG---QKRAPYLRMS--HDTDANL--VITLMLKR--WNLEIPNLVISVTGGAKSF-VLKPRLREMFRRGLIKAAKTTGAWIITGGTNTGVMKHVGEAVKEQQLMFGSDT---QVNVIGIATWGIVDKQSDLISEKNGKYPA--LYSMEPTPGHQGA--MLDPNHSHFFLVDDGTEGKYGVEIGMRSRIEEAIMKVKTDSRSEAGSIGVPVVLLVLEGGPNTVATMYELIKKKVPAVVIDGSGRAASVVGFAYNHTIKRNVDGQTINVIDPQYEDEVRAKVVEVFGAKGADKTYSMIKDVLEDEKMISVYSL-DGEISQDIDLAILKALLKANRSSPVAQLNLALAWNRIDLAKSDIFTEEQ--QWTTETLSAAMLTALLDDK--------------------AEFAELFLQNGLSMREFLSLDILCKLYAEVPGNTTIKPLLQKEMGKRQVKTIDMDVVGEVIEELMGDMFESYY---------RKD--GHYFGELASYAEGLVLKNRKSSKDLLANINRIDPLPTPYLDVFLWAVLCNRRELARVLWEAGREPMAAALMASRLLKRMASRA--QEDNTITDISSDLYDHARLFEERAVGVLDECFNENETLSQTLLVRELDHYSRMTALELAVSAESQDFIAHTSCQVLLTRLWMGTMAMNTRWWKVLVCLYLPVLIFPIIYFVPDEQHERQAAEREHQKSLNQKSSKVKSHKEKNDAPVVPVYRSKEEKAVSNDEEARVGTENEEEDFQLEDYIPEIREDDSMEVIMRNKKLGFCDRIMHFYSAPFSKFVGNVVGYLAFIFLYAYVVLFNFPRFDPAKTLGGIHPT--EIVLYFWVFTILIEEIRQLAAKPPKYIKDKVSVYFSDTWNFVDIFSLTVFIIAIILRFFTNSRIFTASRIILSLDIIFFIVRSLQIFSVNRLLGPKLVMIQKMMQDLAQFIIILAVFTIAYGIALHAVMFPSPGIYARNNTWVTITSVVQYPYWQMYGELFLDEIQGEKPKEFGE-VDPDGRWLSPLLLAIYMVFTNILLLNLLIAIFNYTFERVQEDSDKVWKFQRYDLVQEYHSRPVFAPPLVLLGHILIFIRWVWRMCRCGHPP-----RGSTMKIGLSPAEMEQMDNWE 1165
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. UniProt/SwissProt
Match: sp|O94759|TRPM2_HUMAN (Transient receptor potential cation channel subfamily M member 2 OS=Homo sapiens OX=9606 GN=TRPM2 PE=1 SV=2) HSP 1 Score: 297.36 bits (760), Expect = 2.836e-81 Identity = 295/1116 (26.43%), Postives = 506/1116 (45.34%), Query Frame = 3
Query: 132 NGFEDQIQEFINKKFNTRTCYKYKEKSK------DICHCNRHLNHHTNKSNSPE-----EWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENT-SEDEKGKVI-LDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQA---DGFLVQI-----LFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGA-------DKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEV--IQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKK----SNSTEQNRLFDAGDIIAKLSGNLL---------NNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWST-QDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIII-TIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF-DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGEL------MLENFDVAGPCNGTD-----CIVSSGT----------VLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
N ++ + +I + + C + E SK +C C H ++ P +W + FG I F+G + K++R D +Y LMT +W + P ++IS+ GG KN ++ K F++GL+ V + W+I G G+ K V EA+ +F + ++ IGV+TWGTV + L I F E ED +G + LD+ + F+ DDGT QY E+ + E F+ +Q G ++I + EGG L A + P VV++GSGRVA++I++V LP + +I I + + Q ++ + E+T + ++ + V + D D ILQA++ + ++ LKL + +N +IA +F DE + + +L NKPEFV LF+EN + FV L LYE + D C H + + + + + + ++ ++ +L G+ N++ L P ++ + S LY+ F+ +DL +WA++ R +L+ I+W S++ I +AL + ILK+++ + L +++Y+ A + T+ Y K + + LL R W TCLQ+A+ ++F++H +++ TKVW G LS W++ + + F L L L+ +F K L D T F+ AP+V F +++LSY FL +FAY +V+ +P+ W E IY+++ + EE+RQ+F D + G K YF WNK D I++F+A + R IP + R + S+ +F +R M + ++K++GPKII+++ M++D+ FFL + ++V+++G+ +++ N LF+ VY + FG++ + N + P NGTD C S T ++ ++LL TN+LL+NLLIAMF YTF Q+QE ++++W F R L++E++G+P PPP + H
Sbjct: 53 NDKQESLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEATKPHTFQGTQWDPKKHVQEMPTDAFGDIVFTGL----SQKVKKYVRVSQ----DTPSSVIYHLMTQ--HWGLDVPNLLISVTGGAKNF-NMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELITIGVATWGTVHRREGL-------IHPTGSFPAEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIDNATTNGTPCVVVEGSGRVADVIAQVANLPVSDI--TISLIQQKLSVFFQEMFETFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIF----MDEWQWKPSDLHPTMTAALISNKPEFVKLFLENGVQLKEFVTWDTLLYLYE-NLDPS--------CLFHSKLQKVLVEDPERPACAPAAPRLQMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQGVSLRS---LYKRSSGHVTFTMDPIRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKEEEDTDSSEEMLAL---AEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLI-------------------SFREKRLQDVG-----------TPAARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVPS-------WCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRL-IPATLYP-GRVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFGQIPGYIDGVNFNPEHCSP-NGTDPYKPKCPESDATQQRPAFPEWLTVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPPPFILLSH 1089
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. UniProt/SwissProt
Match: sp|E9PTA2|TRPM2_RAT (Transient receptor potential cation channel subfamily M member 2 OS=Rattus norvegicus OX=10116 GN=Trpm2 PE=1 SV=3) HSP 1 Score: 295.434 bits (755), Expect = 1.114e-80 Identity = 293/1123 (26.09%), Postives = 509/1123 (45.33%), Query Frame = 3
Query: 75 LKRSCYMEMKNTKSEITIKNGFEDQIQEFINKKFNTRTCYKYKEKSK------DICHCNRHLNHHTNKSNSP-----EEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQA---DGFLVQI-----LFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGA-------DKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDI-------IAKLSGNLLNNQYSQLFDKP-LIERDFLTDSFEEFAM---------LYESDVDAHKFSWS-TQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIII-TIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF-DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELML----ENF--DVAGPCNGTD-----CIVSSGT----------VLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGK 3242
L+RS K+ + + + ++ + +I + + C + E SK +C C H + P +EW + FG I F+G + K++R D + +Y+LMT +W + P+++IS+ GG KN ++ K F++GL+ V + W+I G G+ K V EA+ +F + V IG++TWGT+ N + L + +Y E + LD+ + F+ DDGT QY E+ K E F+ +Q G ++I + EGG L Y AI + P V+++GSGRVA++I++V LP +I I + + Q + ++ E+T + ++ + V + D D ILQA++ + ++ LKL + +N +IA +F+D + + M +L NKPEFV LF+EN LKE +++D+ C L +L + KL +K + E RL A + +A++ LL + L+ +P +R L+ + LY+ F+ +DL +WA++ +L+ I+W S++ +AL + ILK+++ + L D +++ A + T+ Y K + + LLVR W TCLQ+A+ ++F++H +++ TKVW G L W+II+ + F L + +F K L + + + + F+ AP+V F +++LSY FL +FAY +V+ +P W E IY+++ + EE RQ+F D + G YF WNK D I++FIA + R IP + R + S+ MF +R M + ++K++GPKII+++ M++D+ FFL + ++V+++G+ +++ N +F+ ++Y + FG++ NF D P NGTD C S T + ++LL N+LL+NLLIAMF YTF ++QE ++++W F R L++E++G+
Sbjct: 33 LRRSNSSLCKSRRLLCSFSSEKQENLSSWIPENIKKKECVYFVESSKLSDAGKVVCECGYTHEQHIEVAIKPHTFQGKEWDPKKHVHEMPTDAFGDIVFTGL----SQKVGKYVRLSQ----DTSSIVIYQLMTQ--HWGLDVPSLLISVTGGAKNF-NMKLRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSCKEGDVITIGIATWGTIHNREALIHPMGG-----FPAEYMLDEEGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTKLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIYNAITNGTPCVIVEGSGRVADVIAQVAALPVSEI--TISLIQQKLSVFFQEMFETFTENQIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFTDEW--QWKPSDLHPMMTAALISNKPEFVRLFLENGVR---------LKEF--VTWDTLLC----LYENLEPSCLFHSKL-QKVLAEEHERLAYASETPRLQMHHVAQVLRELLGDSTQLLYPRPRYTDRPRLSLPMPHIKLNVQGVSLRSLYKRSTGHVTFTIDPVRDLLIWAIIQNHRELAGIIWAQSQDCTAAALACSKILKELSKEEEDTDSSEEMLALAD---EFEHRAIGVFTECYRKDEERAQKLLVRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLCVDNGLWRIILCMLAFPLLFTGFI-------------------SFREKRL------------QALCRLARVRAFFNAPVVIFYLNILSYFAFLCLFAYVLMVDFQP-------SPSWCEYLIYLWLFSLVCEETRQLFYDPDGCGLMKMASLYFSDFWNKLDVGAILLFIAGLTCRL-IPATLYP-GRIILSLDFIMFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNESRVDWIFRGVIYHSYLTIFGQIPTYIDGVNFSMDQCSP-NGTDPYKPKCPESDWTGQAPAFPEWLTVTLLCLYLLFANILLLNLLIAMFNYTFQEVQEHTDQIWKFQRHDLIEEYHGR 1075
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. UniProt/SwissProt
Match: sp|Q91YD4|TRPM2_MOUSE (Transient receptor potential cation channel subfamily M member 2 OS=Mus musculus OX=10090 GN=Trpm2 PE=1 SV=2) HSP 1 Score: 291.197 bits (744), Expect = 2.422e-79 Identity = 291/1101 (26.43%), Postives = 496/1101 (45.05%), Query Frame = 3
Query: 141 EDQIQEFINKKFNTRTCYKYKEKSK------DICHCNRHLNHHTNKSNSP-----EEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQA---DGFLVQI-----LFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGA-------DKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDI-------IAKLSGNLLNNQYSQLFDKP-LIERDFLTDSFEEFAM---------LYESDVDAHKFSWS-TQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIII-TIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF-DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELML----ENF--DVAGPCNGTD-----CIVSSGT----------VLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGK 3242
++ + +I + + C + E SK +C C H + P +EW + FG I F+ + K++R D +Y+LMT +W + P ++IS+ GG KN ++ K F++GL+ V + W+I G G+ K V EA+ +F + +V IGV+TWGT+ N + L + +Y E + LD+ + F+ DDGT QY E+ K E F+ +Q G ++I + EGG L Y AI + P V+++GSGRVA++I++V LP +I I + I Q + ++ E+T + ++ + + + D D ILQA++ + ++ LKL + +N +IA +F+D + + M +L NKPEFV LF+EN LKE +++D+ C L +L + KL K E+ RL A +A++ LL + L+ +P +R L+ + + LY+ F+ +DL +WA++ +L+ I+W S++ +AL + ILK+++ + L D +++ A + T+ Y K + + LLVR W TCLQ+A+ ++F++H +++ TKVW G L W+II+ + F L + +F K L A P + + F+ AP+V F +++LSY FL +FAY +V+ +P W E IY+++ + EE RQ+F D + G YF WNK D I++FI + R IP + R + S+ MF +R M + ++K++GPKII+++ M++D+ FFL + ++V+++G+ +++ N +F+ +VY + FG++ NF D P NGTD C S T + ++LL N+LL+NLLIAMF YTF ++QE ++++W F R L++E++G+
Sbjct: 55 QENLSSWIPENIKKKECVYFVESSKLSDAGKVVCACGYTHEQHLEVAIKPHTFQGKEWDPKKHVQEMPTDAFGDIVFTDL----SQKVGKYVRVSQ----DTPSSVIYQLMTQ--HWGLDVPNLLISVTGGAKNF-NMKLRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSCKEGEVITIGVATWGTIHNREGLIHPMGG-----FPAEYMLDEEGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTKLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIYNAINNGTPCVIVEGSGRVADVIAQVATLPVSEI--TISLIQQKLSIFFQEMFETFTENQIVEWTKKIQDIVRRRQLLTIFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFTDEW--QWKPADLHPMMTAALISNKPEFVRLFLENGVR---------LKEF--VTWDTLLC----LYENLEPSCLFHSKLQKV--LAEEQRLAYASATPRLHMHHVAQVLRELLGDSTQLLYPRPRYTDRPRLSMTVPHIKLNVQGVSLRSLYKRSTGHVTFTIDPVRDLLIWAVIQNHRELAGIIWAQSQDCTAAALACSKILKELSKEEEDTDSSEEMLALAD---EFEHRAIGVFTECYRKDEERAQKLLVRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLCVDNGLWRIILCMLAFPLLFTGFI-------------------SFREKRL---QALCRPAR---------VRAFFNAPVVIFHMNILSYFAFLCLFAYVLMVDFQP-------SPSWCEYLIYLWLFSLVCEETRQLFYDPDGCGLMKMASLYFSDFWNKLDVGAILLFIVGLTCRL-IPATLYP-GRIILSLDFIMFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNESRVDWIFRGVVYHSYLTIFGQIPTYIDGVNFSMDQCSP-NGTDPYKPKCPESDWTGQAPAFPEWLTVTLLCLYLLFANILLLNLLIAMFNYTFQEVQEHTDQIWKFQRHDLIEEYHGR 1074
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. UniProt/SwissProt
Match: sp|Q8CIR4|TRPM6_MOUSE (Transient receptor potential cation channel subfamily M member 6 OS=Mus musculus OX=10090 GN=Trpm6 PE=2 SV=1) HSP 1 Score: 281.952 bits (720), Expect = 4.439e-76 Identity = 301/1216 (24.75%), Postives = 541/1216 (44.49%), Query Frame = 3
Query: 153 QEFINKKFNTRTCYKYKEKSKD---------ICH------CNRHLNHH----------TNKSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQA------DGF-LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMIS------EVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDM-MDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGN-------------LLNNQYSQ----------LFDKPLIERDFLTD-----------SFEEFAMLYES----------------------DVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMA------DLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTW-KIIITIPFSLFLMKLMI-----MPSFPRKG-------------KNPKDVPDAKNFHNKHLLDENAKAP---PLKS--EEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVSSGTVLISF--AVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFEQFCLNE 3419
+ +I F R C K+ SKD ICH C R + H + + E+WS +T FG I F + H H K+IR + D + LM WN+ P ++IS++GGL+N + IS+ K+ F QGL+ + W+I G+++G+ K V +A+ + H ++ +G+ WG ++N + L +G ++V Y+ L+ ++ F+ CDDGT Y E + E + Q G +V ++ EGG +L ++ +K+K P+VV +G+GR A++++ E G+ KE + F +++N + + + L+E + K I I+D + + D IL A++ G S+ L L + ++ +IA K + + ++ + G +++ L +L ++ +FV L +EN ++ F+ L+ELY ++++ P + L L +D K + L S+ + L D G +I L G L NN Y + L L +R L + F A Y+S + +A F + DL +WA+L R +++M W+ + A+ A+I+ + MA ++V ++ +L + S+++ LA ++ +A+ +++ LL L W+ TCL++A++G + F++HS + T +WMG L +W KIII+I ++ L M P+ N K+ K++ + DE P L++ + + + + + FY AP VKF + ++Y+ FLM+F Y LVE++P + E + IY+ T AIE++R++ E + K K + WN + V I +F R+ P R ++ I + + R M F+ VN+ GP + MI M ++ + + I I ++++G+ +++ P + L +DIV+ P++ +GE+ + DV N T C G+ L F AV+L + ++++NLLIA F + I+ S KLW + R + + ++ KP PPP + H ++ C P+ E + L L K KL++FE+ C+ +
Sbjct: 5 KSWIEGVFYKRECNKFIPSSKDPHRCTPGCQICHNLVRCYCGRLIEEHHGLDRAWNLSVTEGHGDEQWSVEKHTVKSPTDTFGTINFQ---DGEHIHHSKYIRTSWDTKSD----HLLHLMLKE--WNMELPKLVISVHGGLQNFK-ISSKLKETFSQGLVKAAETTGAWIITEGINSGVSKHVGDAL---KAHSSKSLRKIWTVGIPPWGVIENQREL-------VGKDVVCMYQTLGNPLSKLTTLNCMHSHFILCDDGTVGMYGNEEKLRRNLEKHLSMQKIHTCSRQGVPVVGLVMEGGPNVILWVWETVKNKEPVVVCEGTGRAADLLAFTYKHLEDGGILRPQVKEEL-FCLIQNMFNFSL-------RQSKHLFQILMECMVH-KDSITIFDADSEEHQDLDLAILTALLKGTSLSISEQLNLAMAWDRMDIAKKHILTYGQHWKPG--ALEQAMLDALVMDRVDFVKLLIENGVNLHRFLTIPRLEELY----NTKQGPTNKFLRHLVQDVKQHTLL-----SSYRITLIDIGLVIEYLIGGAYRSSYTRKSFRILYNNLYRKHKSVSSFAQGLSQHSLHQRHSLRNRKESSESTLHSQFFRTAQPYKSKEKPEDSQKSKKKSKERQSLSEEPEAAGFIYPYNDLLVWAVLMKRQNMAMFFWQHGEEATVKAVIASILYRAMAREAKESNMV-----DDTSEELKNYSEQFGQLALDVLEKAFKQNEPMAMKLLTYELKNWSNSTCLKLAVSGGLRPFVSHSCTQMLLTDMWMGRLKMRKNSWLKIIISILLPPMILTLEFKSKAEMSHVPQSQDFQFTWNYSDQGLSNTKESACVKDYDLERGPDEKPDEPLHLDLRNVPQSLPWTRRVYEFYSAPFVKFWFYTMAYLAFLMLFTYTVLVEMQPQPSVH-------EWLVIIYIFTNAIEKVREICISEPSKFKQKVKMWLSEYWNLMETVAIGLFAVGFGLRWGHPPLQ-TAGRLIYCIDIIFWFSRLMDFFAVNQHAGPYVTMIAKMAANMFYIVIIMAIVLLSFGVARKAILSPKEPPSWRLARDIVFEPYWMMYGEVYASDIDVCS--NETSC--PPGSFLTPFLQAVYLFVQYIIMVNLLIACFNNIYLDIKSISNKLWKYNRYRYIMTYHQKPWLPPPFILLNHLCLLLRGLCCRPAPQDQEEGDGGLKLYLTKDDLK-KLHDFEEQCVEK 1162
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. TrEMBL
Match: A0A267F5R1 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006430g1 PE=4 SV=1) HSP 1 Score: 400.593 bits (1028), Expect = 2.580e-114 Identity = 322/1180 (27.29%), Postives = 570/1180 (48.31%), Query Frame = 3
Query: 162 INKKFNTRTCYKY--KEKSKDICHCNR---------------------HLNHHTNKSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNL---VFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQ-------ADGF-------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDA-EVEEFTNYLVEMY-CNFKKQIVIYDM--MDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSD---PKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISF---DSEKCPCAELLCDLHRDTKSY---------FKLNKKSNSTEQNRLFDA-GDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIIT------IPFSLFLMKLMIMPS----------------FPRKGKNPKDVPDAKNFHNKHLLDEN------AKAPPLKS-------------EEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELK-PIQEIKSIKQVWAEIYIYI-YVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAG-----------PCNGT------------DCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPK 3323
I F R C+++ + S IC CNR + + + P+ W+ T +G ++F + K+IR DC ++ +++L+T + W IP+P +I+S+ GG K M +S+ KK +QG+I++ K TW++ G + G +KLV EAI +++ +D V LIGV WG+V++ + L + + + +L ++ + + KG+ +L+ + FL CDDGTE + E++F FE V +Q DG V ++ EGGR+ + A +++ P+VV+KGSGR AN+I+ + ++ + IE I E+ + E D+ E+ ++L+++ +++ + +YD MD N D+ IL + S+ L L + +N ++A + +FS K+++L ++ L +L N+ EFV+L ++ ++ +N L LY D + E L L S+ + + +S + Q RL A G ++ SG +L + Y + RD + S+ +DL +W+++ RTD++ I+WR + + I SAL +A++L+ M L G +L A+ ++ LA+ ++ Y + K KT LVR L W+G T L +A G +EF++ A ++ + +W+ +LP W+ +I IP +F L+ P R PK V ++F ++H + P L+ + +F++ + +FY +P VKF + S +VFL++F++ LV LK P + + Q ++ I ++++ EEIRQ+FD+ A K +F W+ FD V+ ++ I+ ++ R + + +F+ R ++++L+MF IR MQFY +++++GPK++M+ M+ D +FF +I V+F++ YG+ A++L YPNS + L KD+VY P++Q +GEL L + P N T V S V++ FA ++L+TNVLL+NLLIAMF +TF+ +QE S KLW + R QL+ EF+ +P PL + H ++ ++ C +
Sbjct: 84 IYSSFQKRECFQFVPRANSPRICCCNRSAAWHASKAAAAAAVTDITDARADTLSRTARMPKRWTVDGCTATARTDAYGVLRFENFEFTRLGQNAKYIRLDC---LNSRPNLLWKLLTKT--WRIPEPELIVSVTGGAKKMRPMSDKIIKKLRQGIINIATKTKTWIVTGGFNLGTNKLVGEAIRDYQLAGGSERD-VVLIGVCPWGSVRDKECLLVSEDKSLEDDLPVSTYRNPDNTAPVKGQAVLEPHHTHFLLCDDGTESMFGAEIDFRASFEKKVAEQMVRRRSRGDGSDLRSVTPCVHLIIEGGRKDVQAALVSVETGSPVVVVKGSGRAANVIAYICE-NTELERYEIEAITEEH-----FSSEFEPDSSEMRSLVDWLMKLAEPAYQRMLNVYDAESMDPNEQLDRVILTTFLRQTSLSVVTQLNLAMAWNRPDLAAQEIFSSERKAKWEQLTGRDLEYSMLRALARNQTEFVSLLFDHGINIGTLLNLETLAGLYSSLINKPDPQMMRLREQLDYLSSPLSSWLMTESKTVGYATHNESQTAYQERLLRAVGLYVSAKSGGVLRSPYPR--------RD--------------------RSSYQAEDLLIWSIVVQRTDMARIIWRQTSDTIASALVSAMMLRNMKSLAESEGSLEASAQLGAAADSFEGLAAGVLATCYAQDKQKTLDTLVRRLPVWDGQTLLTLADQGECMEFMSQQAVQTKISDIWIAGSKTYLPLWRTLICMLLPMLIPALIFDKWLLTSPPAGESTGAGSDRHSSVRMKRSSVQPKTVSTRQSF-DRHQQQQQQQQKQQGATPSLRKSQQQQQVSSGGHIQNPSFLQCVFMFYTSPQVKFISTVASAVVFLLLFSFVTLVTLKHPNEATEEEPQPSVLEFVLIGWMVSLIAEEIRQIFDRNKVSALEKLKDWFAHAWDVFDLVLNLMMISCILVRVFVTEEYFVWVRMTYALTLTMFYIRFMQFYLIHQTLGPKVVMVTRMINDTVFFFAILVVFLLAYGVAAQALLYPNSPLSWKLIKDVVYLPYWQMYGELQLGDILADDDKVSPDSPPIMPSNVTGRGFEGGGEGEESEAVHSPLVIVLFAFYMLITNVLLLNLLIAMFQHTFDLVQESSRKLWAYSRYQLIFEFHHRPFLCHPLTVLCHIANVLERLWRAACGR 1222
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. TrEMBL
Match: A0A267G848 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig004998g1 PE=4 SV=1) HSP 1 Score: 395.201 bits (1014), Expect = 1.876e-112 Identity = 319/1181 (27.01%), Postives = 566/1181 (47.93%), Query Frame = 3
Query: 162 INKKFNTRTCYKY--KEKSKDICHCNRHL---------------------NHHTNKSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNL---VFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQ-------ADGF-------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLE-NKITLQICTGPEE--DAEVEEFTNYLVEMY-CNFKKQIVIYDM--MDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSD---PKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISF---DSEKCPCAELLCDLHRDTKSY---------FKLNKKSNSTEQNRLFDA-GDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIIT------IPFSLFLMKLMIMPS----------------FPRKGKNPKDVPDAKNFHNKHLLDEN-----AKAPPLKS-------------EEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELK-PIQEIKSIKQVWAEIYIYI-YVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAG-----------PCNGT------------DCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPK 3323
I F R C+++ + S IC CNR + + + P+ W+ T +G ++F + K+IR DC ++ +++L+T + W IP+P +I+S+ GG K M +S+ KK +QG+I++ K TW++ G + G +KLV EAI +++ +D V LIGV WG+V++ + L + + + +L ++ + + KG+ +L+ + FL CDDGTE + E++F FE V +Q DG V ++ EGGR+ + A +++ P+VV+KGSGR AN+I+ + E+ E E IT + + E +E+ ++L+++ ++++ + +YD MD N D+ IL + S+ L + + +N ++A + +FS K+++L ++ L +L N+ EFV+L ++ ++ +N L LY D + E L L S+ + + +S + Q RL A G ++ SG +L + Y + RD + S+ +DL +W+++ RTD++ I+WR + + I SAL +A++L+ M L G +L A+ ++ LA+ ++ Y + K KT LVR L W+G T L +A G +EF++ A ++ + +W+ +LP W+ +I IP +F L+ P R PK V ++F + P L+ + +F++ + +FY +P VKF + S +VFL++F++ LV LK P + + Q ++ I ++++ EEIRQ+FD+ A K +F W+ FD V+ ++ I+ ++ R + + +F+ R ++++L+MF IR MQFY +++++GPK++M+ M+ D +FF +I V+F++ YG+ A++L YPNS + L KD+VY P++Q +GEL L + P N T V S V++ FA ++L+TNVLL+NLLIAMF +TF+ +QE S K+W + R QL+ EF+ +P PL + H ++ ++ C +
Sbjct: 85 IYSSFQKRECFQFVPRANSPRICCCNRSAAWHASKAAAAAAVTDITDASADTLSRTARLPKRWTVDGCTATTRTDAYGVLRFENFEFTRLGQNAKYIRLDC---LNSRPNLLWKLLTKT--WRIPEPELIVSVTGGAKKMRPMSDKIIKKLRQGIINIATKTKTWIVTGGFNLGTNKLVGEAIRDYQLAGGSERD-VVLIGVCPWGSVRDKECLLVSEDKSLEDDLPVSTYRNPDNTAPVKGQAVLEPHHTHFLLCDDGTESMFGAEIDFRASFEKKVAEQMVRRRSRGDGSDLRSVTPCVHLIIEGGRKDVQAALVSVETGSPVVVVKGSGRAANVIAYIC--------ENTELERYEIEAITEEHFSSEFEPNSSEMRSLVDWLMKLAEPDYQRMLNVYDAESMDPNEQLDRVILTTFLRQTSLSVVTQLNMAMAWNRPDLAAQEIFSSERKAKWEQLTGRDLEYSMLRALARNQTEFVSLLFDHGINIGTLLNLETLAGLYSSLINKPDPQMMRLREQLDYLSSPLSSWLMTESKTVGYATHNESQTAYQERLLRAVGLYVSAKSGGVLRSPYPR--------RD--------------------RSSYQAEDLLIWSIVVQRTDMARIIWRQTSDTIASALVSAMMLRNMKSLAESEGSLEASAQLGAAADSFEGLAAGVLATCYAQDKQKTLDTLVRRLPVWDGQTLLTLADQGECMEFMSQQAVQTKISDIWIAGSKTYLPLWRTLICMLLPMLIPALIFDKWLLTSPPAGESTGAGGDRHSSVRMKRSSVQPKTVSTRQSFDRHQQQQQQQHKQQGATPSLRKSQQQQQVSSGGHIQNPSFLQCVFMFYTSPQVKFISTVASAVVFLLLFSFVTLVTLKHPNEATEEEPQPSVLEFVLIGWMVSLIAEEIRQIFDRNKVSALEKLKDWFAHAWDVFDLVLNLMMISCILVRVFVTEEYFVWVRMTYALTLTMFYIRFMQFYLIHQTLGPKVVMVTRMINDTVFFFAILVVFLLAYGVAAQALLYPNSPLSWKLIKDVVYLPYWQMYGELQLGDILADDDKVSPDSPPIMPSNVTGRGFEGGGEGEESEAVHSPLVIVLFAFYMLITNVLLLNLLIAMFQHTFDLVQESSRKVWAYSRYQLIFEFHHRPFLCHPLTVLCHIANVLERLWRAACGR 1223
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. TrEMBL
Match: A0A2C9K628 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106052735 PE=4 SV=1) HSP 1 Score: 344.354 bits (882), Expect = 1.034e-95 Identity = 319/1130 (28.23%), Postives = 546/1130 (48.32%), Query Frame = 3
Query: 102 KNTKSEITIKNGFE----DQIQEFINKKFNTRTCYKYKEKSKD---------ICHCN----RHLNHHTNKSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAE--VEEFTN--------------YLVEMYCNFKKQIVIYDMMDANMS--FDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSA-LFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITI---PFSLFLMKL-------MIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKS------EEI-TFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPC--NGTD--------CIVSSGT--VLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
K + SE +I + +E ++ +FI R C +KEK + +C+CN H + + + WS S+NT +G I+F G+ + K++R D + D ++ +L+T W + P ++IS+ GG KN ++ K+ F++GL+ + W++ G AG+ K V EA+ +F + +V+ IG++TWG V+N + L R +N +Y E + + LD + F+ D+GT+ Q+ E+ F K E + K+ G + ++ EGG L Y A+K P VVIKGSG+ A++++ Y+ + E V + + +I + DAE ++E V+ C K + ++++ N + D IL+A++ LKL + +N ++A +F+D + G+ + E+ + ++K ++ +FV LF++N + NF+ L LY P LL L TK + L D G ++ L G+ F +P +LTD +S+++ F Q+LF+WALL LS + WR K +A LFA +LK + + D + +KL A++ Y++L + +I Y+ + +T+ +LV+ + W TC+QIA++ + F++ +A +S TKVWMG++S P + I++ I P LF +K + S K + P N H KH D + + KS E+I I+ + FY +PIVKF +++++Y+VFL +++Y +V+L +EI W E + +V++ +EE+R+ F + K +Y WN D V I++F + RF + R + SI+L F R +Q + +NK +GPK++MI ML+D+ +F+ I ++F+++Y + + ++ YPNSE + L + ++Q +GEL L++ + C N T+ C G V I ++LMT VLL+NLLIAMF YTF QIQ +++ WCF R +LV E+ +P FPPPL +F H
Sbjct: 8 KQSHSESSIMDKYECDESNEGMQFIKYNIKCRECTFFKEKPEQEALVKEEDKVCYCNYLKKEHSKNALRRKSRTHLWSLSDNTEKTPTNAYGEIEFVGFGD----RIGKYVRVDVDTPMD----TMLDLLTK--VWKMEMPNLLISVTGGAKNF-NMKARLKEVFRRGLVKAAQSTGAWIVTGGTYAGVMKHVGEAVRDFGLTSQG---RVTTIGIATWGCVQNKELLIRKDE---DSNHPVEYSIHGEVKPKQSFLDPNHSHFILVDNGTQHQFTVEIPFRAKLEEAISKRKTGTDAITVPVCLLVLEGGPGTLETVYSALKSTTPTVVIKGSGKTADILAYA-------YQNTKEEEVKQEESGKKIINTLDPDAEEKIKEMIKSSFGVAELEIEKCFIWVKECCARKDLLSVFELDSKNSAKDVDLAILKALLKANKNQAIDQLKLALAWNRIDVAKSEIFTDDRTWPTGM--LDEIMMSAIKLSRVDFVELFLDNGLSLKNFLTKERLTALYNT------IPPNCLLRSLLMKTKRKHEFT----------LVDVGHLLQDLLGD---------FYQPC----YLTDG--------QSNLET--FITPAQELFIWALLMNNLKLSKLFWREGKQSSTAACLFAHSVLKSLQAHTI---DAKVIKKLQTAAEDYEELVNGVIKSCYSSDEERTHNILVQYMPHWGRTTCVQIALHSDNQLFISQNAFQSMLTKVWMGNMSQSNPFYMILVGIVIFPVVLFCVKFNETNTKQKRLSSSSTKHHQIETHPTI-NGHAKHKSDHSLNSTKEKSRTKGHTEQIKKMIQKLKCFYCSPIVKFVMNVMTYLVFLALYSYLLVVQL--TREIH-----WIEGVLIAWVISLFLEELREYFTY---SNQSKLKTYLKNKWNYLDIVCILLFALGISLRFVPDDDCMTAARVILSINLITFFFRILQIFSINKQLGPKLVMIGKMLQDLKWFVVILLVFIVSYALASEAVLYPNSEPSWKLLYFVPRKAYWQIYGELFLDDIEDPETCTNNATEYSTYTIKRCPSEVGKYFVPILLGFYMLMTTVLLLNLLIAMFSYTFEQIQGNTDMHWCFQRFKLVLEYTERPAFPPPLILFSH 1058
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. TrEMBL
Match: A0A4W3H5R4 (Uncharacterized protein OS=Callorhinchus milii OX=7868 PE=4 SV=1) HSP 1 Score: 333.569 bits (854), Expect = 2.434e-91 Identity = 307/1124 (27.31%), Postives = 522/1124 (46.44%), Query Frame = 3
Query: 141 EDQIQEFINKKFNTRTCYKYKEKSKDICHCNRHLNHHTNKSNS------PEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENT-SEDEKGKV-ILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF--------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKS-------MKRTLKLCIRFNCSNIADKIVFSDPK-YDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCD-LHRDTKSYFKLNKKSNSTEQNR--LFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPR----KGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEIN-GAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGEL---MLENFDV-AGPCNGTD-----C---------IVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKL--IFEQENNLML 3356
+D +++I + C Y E + +C C +HH+ ++ S +W Y + FG I F G N K++R ++YELMT W + P ++IS+ GG KN + + F +GLI V K W+I G AG+ K V EA+ + + +V IGV+TWG V N + L I +F E T E+ +G++ LD + F+ DDGT +Y E+ E ++ KQ G ++ ++ EGG L + A+ + +P V+++GSGR A++++ V LP +I + + + D + +T + ++ + V N D ILQA++ + + ++ LKL + ++ +IA +F+D K + L Q MF +L NKP FV LF+EN ++ FV IL+ LY P + LL L + + + + N + R L I+ +L G+ Y + D + L S + + + + DV+ +F +DLFLWA+L R L+ ILW S + I SAL A ILKK++ D +L + + +++Y+D A + T+ Y K + LL+R W TCL++AI G+ F+ +S+ TK+W GD+S TW++++ + + I SF + + K V + + K L + ++ + + FY AP+V F ++L+Y FL +F+Y L++ + + E ++Y+++ T EEIRQ+F + G K + YF WNK D I++F+ + R+ F R + + ++ R M + VNK++GPKIIM++ M++DI FFL + + ++ +G+ + + N + +F+ +VY P+ FGE+ ++ FD+ G+D C I +I ++LL TN+LL+NLLIAMF YTF +QE+++K+W F R L++E++ +P PPP I H + R P++ E+E + L
Sbjct: 25 QDGFKKWIYENLMKMECVCYVENPELVCSCGYLKDHHSGEAISHGYRQEGNKWIYERHVRQVPTDAFGDIVFEGQRN------GKYVRVSS----GTAPATLYELMTKQ--WGLNPPHLLISVTGGAKNF-YLKPSLRNLFCRGLIKVAKSTGAWIITGGSHAGVMKHVGEAVRRYTMTSSSKEGEVVAIGVATWGIVHNRECL-------INKEGMFPVEYTLDEENQGRLSCLDHNHSHFILVDDGTHGKYGVEILLRSNLEKYISKQRMGTEDVGIETPIICVVLEGGEGTLNTIHSAMMNGMPCVIVEGSGRAADVLASVANLPVSQI--TISLMQKQLRTFFSETFNTFSDRRIISWTKKVQDIVRMHQLLTVFKAEKARNQELDVAILQALLKASSNASHLGKENLEHQLKLAVAWDRVDIAKSEIFTDKKRWKSSNLH--QAMFA-ALVGNKPGFVELFLENGVNLGEFVTPEILERLYN------NVPQSTLLYKKLRKAVEGERRRDASDNVDAKQRILLHHVSGILRELLGDFTEPFYEKPKDHQCKKHLKLKHSDSQESEICD-DVE-QEFEEPARDLFLWAILQKRKMLANILWVQSSDSIASALVATKILKKLSSEA---NDTDLSEAMEELAQEYEDRAIGVFTECYRKDPKRAQKLLIRVSNAWGNTTCLRLAIEGDDQNFMAQGGVQSFLTKIWWGDISVDTQTWQVLLCMVLWPIIHSNFI--SFRQDEEIRMKKASKVDSSSDISQKDL------------KPLSCCERLRAFYTAPVVVFYWNVLAYFGFLWLFSYVLLIDFQSQPSGR-------EYFLYLWLFTLVCEEIRQLFSNPDDLGFWKKAILYFSDIWNKLDVAAILVFLVGLACRWI--SETFYYGRIILCLDFIIYCFRVMHIFAVNKTLGPKIIMVKRMMKDIFFFLFLLALSIVAFGVAKQGILIHNEDRLDWIFQGVVYHPYRMIFGEIPIDVVSGFDLNQCTLTGSDPYKPKCPEHDSNNNPIFPEWITVILLCIYLLFTNILLLNLLIAMFNYTFQLVQENTDKIWKFQRCHLIEEYHSRPSAPPPFIILSHIILFVQCIIIRRPPQIQKRLEEEEDFAL 1089
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. TrEMBL
Match: A0A2B4SPT0 (Transient receptor potential cation channel subfamily M member 3 OS=Stylophora pistillata OX=50429 GN=TRPM3 PE=4 SV=1) HSP 1 Score: 327.791 bits (839), Expect = 9.052e-89 Identity = 320/1162 (27.54%), Postives = 544/1162 (46.82%), Query Frame = 3
Query: 138 FEDQIQEFINKKFNTRTCYKYKEKSKD-------ICHCNRHLNHHTNKSNSPEEWSYSNNTTLDSCVK------FGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAI--SEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGK--VILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKK------QADGFL----VQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQIC-TGP-EEDAEVEEFTNYLVEMYCNFKKQIVIYDM-MDANMS--FDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWST----------------QDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDN---NLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFL-------MKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKA------------------PPL----------KSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQV-WAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPN----SEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVS----SGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAF---RIISLPCKSRCPKLI 3329
E + +I K F R C K + +K +C C R H N E++ N T +SC + +G I F G + ++R + D + + E W++ P ++IS+ GG K+ + K+ F++GLI K W+I G +AG+ K V EA+ E F ED +V++IG++TWG V +L A GTN ++ E G +LD+ + FL D+GTE +Y E+ +FE V K A G + V ++ EGG + + IK K+P VVI GSGR A++++ K+ ++ I + ENKI ++ P ++ EV+E ++E K I IY + + N+S D IL+A++ + L L + +N ++A +F+D K E + + L +L D+KP FV LF++N + F+ IL +LY P ++ L + ++NKKS + L G++I NL+ + Y L+ L + ++T L+E +HK S +D+F+WA+LS R D++ ++W + + I +AL A +LK MA+ R D+ ++ +L + + ++ A ++ + Y ++++ + TLLV+ L + LT L +A+ F+ H++C+ T++WMG ++ WK L MK + S + + V +N + K +DE +K P L +S+++T ++ FY AP KF +L+SY+ F+ ++ Y + P K+ + E +Y ++ T +EEIRQ+ Q+ K YF TWN+ D ++ F+ + RF + + R S+++ +F++RS+Q VN+ +GPK++MIR ML D+ F+ I IF+I YGI +++ +P S+ + + I+ P++Q +GEL LE P + + S +L + +F TNVLL+NLLIA+F YTF ++QEDS+K+W F R +L+ E++G+P+ PPL H R I C+ P +
Sbjct: 50 LEKSKKSWIAKHFKGRECIKIVKDAKKTRSEENPMCMCGRTRQQH--DLNVTREYN-GNQWTPESCTRQMPTDAYGEIDFVGTGS--QNKRSPYVRVSHDTDVQLILKLMLE------RWDLEIPNLVISVTGGAKSF-VLKPRLKEVFRRGLIKAAKSTSAWIITGGTNAGVMKHVGEAVKEQEITFGSED---KVNVIGIATWGIVDRKD----SLKASKGTNGLYPAHYRMEQVPGSSGALLDSNHSHFLLVDNGTEGKYGVEINLRSRFEEAVMKVKTDSRSAAGAIGVPVVLLVLEGGPNTVRTMCELIKKKIPAVVIDGSGRAADVVAYAYSHTIKSEEKFIIDPLYENKIRAKVAEVFPFMKEQEVKEHYK-MIEEVLEDDKMISIYRLDHETNISQDIDLAILKALLKANSSAPLMQLNLALAWNRIDVAKSEIFTDDK--RWTTEGLTDPMLAALLDDKPGFVELFLQNGLSMMEFLTPQILCQLYA------GVPSNSVIKPLVQK-----EMNKKSITALN--LSVVGEVIE----NLMGDSYHCLY---LRDPRYMTS-------LHEERGKSHKISQPAIVCNPLHRIDPLRTPYRDVFIWAVLSNRKDMAKLMWSMGREQIATALMATRLLKSMAEKA--RADDTITDISAELLEVANDFEQHAIGVLQECYEENETLSQTLLVKELDNFGNLTALDLAVIAEDQNFIAHTSCQVLLTRLWMGAMAMNTKWWKHEREAAARLSQKGLYTKSMKNVRRSSITEETVELQKVETVRNGNPKINIDEESKVGEGEDTGEDIVQEIVEYIPELQEDHSMEHMMRSKDMTVYDRITSFYSAPFTKFMGNLVSYVAFIFLYGYVITMYFPPFDSSKTFGGLSVVEFILYFWIFTIIMEEIRQLAAQQPKTFGDKLRVYFSDTWNRVDTFALLAFVVAACLRFF--DSTYEAARITLSLNIIVFIVRSLQIVSVNRQLGPKLVMIRKMLEDLKQFVIILAIFIIAYGIALQAVTFPGPGPFSKTWDQVIRGILDLPYWQMYGELFLEEISGQKPAEYFEVHPTAKWLSPALLAGYMLF---TNVLLLNLLIAIFSYTFERVQEDSDKVWKFQRYELIAEYHGRPLIFPPLIFISHVLIFIRWIWRLCRCGNPPAV 1155
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Cavefish
Match: hrc (transient receptor potential cation channel subfamily M member 4-like [Source:NCBI gene;Acc:103047479]) HSP 1 Score: 233.417 bits (594), Expect = 4.486e-62 Identity = 260/1122 (23.17%), Postives = 489/1122 (43.58%), Query Frame = 3
Query: 183 RTCYKYKEKS---KDICHCNRHLNHHTN-------KSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFR-FHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGFL---------VQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMG-------LPSKNYKESIEF---IVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDM-MDANMSFDKKILQAMI------VGADKSMK-RTLKLCIRFNCSNIADKIVFS-DPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNK--KSNSTEQNRLFDAGDIIAKLSGNLLNNQYS-QLFDKPLIERDFLTDSFEEFAMLYESDVDAHK--FSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIIT--IPFSLFLMKLMIMPSFPRKGKNPKDVPDAKN----FHNKHLLDENAKAPPLKSEEITF-----------------IKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVA------------------GPCNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRII 3293
R C + E S +C C + H S W + +++ FG ++F G + H F+R D + Y ++T S W +P P +++S+ GG+ + ++ +QGL+ + W++ GL GI + + EA+ + D +V IGV+ WG V L +N + + NTS D LD + FL DDG+ + E F EN++ +Q G L + L G L ++K +P +V+ GSG +A+++++V+ LP+ + E I L ++ ++ + +V++ + L+ ++ + + I IY + + FD +L+A++ + +D S+ LKL + +N +IA +F+ D ++ E ++ +L ++KP+FV LF+EN +V ++ L+ELY DS A L H + ++ + L++ ++ L G++ Y +L + + R +L E + + F W++ LF WA+L R+++++ W ++ + SAL A +L+++ L + + L + + K+++LA + ++ Y S+S+++ LL + W G TCLQ+A+ + F +H ++ +++W GD+ WK+++T IP + + + P++ P A++ + + K K EE+ F + F+ AP+ F L + +++ + V L + E+ +Y +V T EEIR F + + Y W+K D + I +F+ + R + F R + +F +R + + ++K +GPKII++ M++D+ FFL ++++ YG+ + L Y + + + Y P+ FG++ E D PC T + V+I ++LL+TN+LLINLLIAMF YTF ++QE S+ W F R +++ E++ +P PP IF H + I
Sbjct: 34 RVCTTFVEDSFSNGHLCQCGGSRDSHATVSLNDYFSSAIVSHWDSALHSSEAPTDAFGEVEFGG---VSKRH-SNFLRLSS----DTPPATAYTILT--SNWGLPKPNLVLSVVGGV-GRSKVKPKLREVLRQGLVRAAQSTGAWILSGGLREGIDRCLGEAVRDHTTAASSDSLTKVVAIGVAPWGLVNLRDEL---VNPEGSYPAGYFVTNTSRD---SYCLDTNHQAFLLVDDGSTGRRGGEARFRAGLENYISQQRTGKLGSGSMDIPVLCTLVSGELYMLERLDLSLKKCIPWMVLAGSGGLADLVTDVLENVAAAPVLPAGGAEGEGEATTKINLRERVAEKVVKHFPSEPDVDKLVDKLLNVHKS-QDLISIYHLEQEGPEDFDTVLLKALVRASKQRLSSDASLSTEELKLAVTWNRVDIARSELFTGDIQWKN---ESLESFMTDALVNDKPQFVRLFIENGLNVQEYMTFGRLEELYRSISDSS---VAYTLLQRHLSERQGVAGTGWPAADPAKGLTLYEVAQLLEDLLGDVCQPFYDDKLKIQGITSRRKTIKKLT--TVLQEGEYRQQRCVFPWAS--LFTWAVLQNRSEMAVFFWEMTPESVLSALSACKLLRELCKL---ENETETKHSLKELAMKFENLAHDVFSKCYQSSESRSFVLLKKKSVVWRGATCLQMAMEADARHFFSHDGVQTLLSQIWWGDMDRNTENWKLVLTLFIPPLCYTSLISFREVEEAEDGTPEEAPKARDIDWLYAETVFSFADIKRIQTKQEELRFTPKGNPTKKSPQKQCFLLSRWKQFWYAPVTAF---LGNMLMYFLFLLLFAYVLLVDFKPPPPKGPSPMELLLYFWVFTIVCEEIRGTFFIGNMTVRQRIRQYTQDLWHKCDLIAITLFLIGLCCRMF--RRSFWFARAALCLDYMVFTLRLIHIFAIHKQLGPKIIIVGKMMKDVFFFLFFLAVWMMAYGVANQGLIYSFDPSADRILRRVFYRPYLHIFGQIPYEQMDSGFEWNVTCTTNVTEIDENMEPCRDTR---YNWMVVILLMIYLLVTNILLINLLIAMFSYTFTKVQERSDVYWKFQRFKVIIEYHSRPCLAPPFIIFSHFHQFI 1116
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Cavefish
Match: trpm5 (transient receptor potential cation channel subfamily M member 5 [Source:NCBI gene;Acc:103047602]) HSP 1 Score: 225.713 bits (574), Expect = 1.294e-59 Identity = 253/1018 (24.85%), Postives = 467/1018 (45.87%), Query Frame = 3
Query: 426 VYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVI-LDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF---------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRT------LKLCIRFNCSNIADKIVF-SDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNS-----TEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAH-KFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPS---FPRKGKNPK-------DVPDAKNFHNKHLLDENAKAPPL-----KSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQ-EIKSIKQVWAEIYIYIYVLTFAIEEIRQVF--DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVA--GPCNGTDCI--VSSGTVLISFAVFX------------XXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCK 3308
+Y+L+T W + P +++++ GG ++ + + ++GL+ + W++ +GL GI K + +A+ + K +V IG++ W + N + L L AK + E+ G V LD + F+ ++ + + + +K + Q G+ ++ +L G + L YK I++ P +++ GSG VA+++ ++ + E ++ ++LE L ++ + + ++ N + ++D + D IL+A++ + LKL + +N +IA +F D ++ LE E+ + +L ++KP+FV LFV+N ++ F+ L+ELY SEK +LL H++ + + ++ F ++ +K+ + L++ + K ER F L D+D H + W +DLFLWA+L R ++ W + + +AL ILK+MA L + R + +A KY+ A + ++ Y+ S+ + Y LLVR W+ T L +A + F H ++ TK+W G ++ K++++ + +I S +G + D A + D A P ++ ++ F+ AP+ F ++L Y FL++F Y L++ +P + SI AEI +Y +V T +EEIRQ F D+++N K K Y WNK D V I +F+ V R +N + R + ++ +F +R + + ++K +GPKII++ M++D+ FFL +++I YG+ ++L +PN +F+ ++Y P+ FG++ LE D A P N T + + +GT+ ++ L+TNVLL+NLLIAMF YTF +Q +++ W F R L+ E++ +P PP I H +I+ CK
Sbjct: 95 IYQLLTEQ--WGLSPPHLVVALVGG-DELDQMKPWLRDTVRKGLVRATQSTGAWILTNGLQFGITKHLGQAVRDHSLASTSSKVRVVAIGIAPWTMIHNKEML---LTAKPDQPAAYPTEDLPH---GSVYSLDCHHSHFILVEE-EQHRSGATGDMRVKLLKHISLQRTGYGGPGSFEIPVLCLLVHGEPKILQRMYKTIQNATPWLLLAGSGGVADILVTLIYRGCWD-TEMVQELLLETFTGLH-------STDITSWVKVIQKILEN-GHLLTVHDP-EQTADLDTVILKALVKACKSQSQEAQDFLDELKLAVAWNRVDIAKSEIFNGDVEWSPQDLE---EVMMDALVNDKPDFVRLFVDNGVNLGEFLTYGRLQELY--CSVSEKSLLFDLLLKKHQEKQMLLASARTPGPPYMEPVDRRPRFTLHEV-SKVLKDFLHDSCKGFYQKLPAERVGKGRLFHSQKDL--PDLDQHCENPW--RDLFLWAVLQNRQKMANYFWAMGPEAVAAALAGCKILKEMAHL---ESEAESARSMKEA--KYEQFALDLFSECYSNSEDRAYALLVRKTHCWSKSTVLNLATEADAKSFFAHDGVQALLTKIWWGAMTTDTSISKLVLSFFCPPLIWTNLIKFSDEILQSRGGGEQFAELDSLDTEKALLLSDDDPDDSEAAGDPADQSCSQAWSQFLLRRWKRFWSAPVTVFLGNVLMYFAFLVLFTYVLLLDFRPPPPDGPSI----AEIILYFWVFTLVLEEIRQSFFTDEDMNILK-KCKLYVEDNWNKCDMVAISLFVVGVSCRMM--ENTYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLIAYGVATQALLHPNDPRLDWVFRRVLYRPYLHIFGQIPLEEIDAAKMQPDNCTMDLQDIITGTLPPCPNIYANWLVILLLVIYLLVTNVLLLNLLIAMFSYTFQVVQGNTDIFWKFQRYNLIVEYHSRPALAPPFIIISHLSQILLSLCK 1070
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Cavefish
Match: trpm4a (transient receptor potential cation channel subfamily M member 4 [Source:NCBI gene;Acc:103041664]) HSP 1 Score: 204.142 bits (518), Expect = 7.874e-53 Identity = 183/777 (23.55%), Postives = 344/777 (44.27%), Query Frame = 3
Query: 102 KNTKSEITIKNGFE--DQIQEFINKKFNTRTCYKYKEKSK---DICHCNRHLNHHTNKSNSP-------EEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISE-FRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF---------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVM------GLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMI-----VGADKS-MKRTLKLCIRFNCSNIADKIVF-SDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNR---------------LFDAGDIIAKLSGNLLNNQYSQLFD-KPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLT--DASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMI 2273
++ K E + +NG ++ Q ++ K + C + E S+ D C C H++ + +W + +T+ FG ++F+G H H F+R C D VY +MT +W +P P +++S+ GG E + + + +QGL+ + W++ GL G+ V EA+ + + +V IGV+ WG V N Q+L +NA+ + +NTS D LD Y FL DDG+ E F+ E+++ Q G ++ +L G L ++K P +V+ GSG A+MISE++ P+ L N+ I + +E+ + + +Y N V + D+ FD +L+A++ + +D S LKL + +N +IA +F D ++ E +++ +L +NKP+FV +F+EN ++ ++ L+ LY+ DS LL R+ S ++ S + + + L++ ++ +L G + Y + D P + + W++ LF+WA+L R+++++ W ++ + SAL A +L+++ L +N + KL+ + ++K++ LA + Y S+S+++TLL+R+ W G+TCLQ+A+ + F +H ++ +++W GD++ WK++ + FLM +I
Sbjct: 3 QSEKEEESARNGSGKGEKDQSWVPKIIKKKVCTTFLEDSQSNGDRCQCGSERAAHSSSATGDFFGSAVVSQWDTAVHTSEYPTDAFGEVEFAG-AGRRHSH---FLRLSC----DTPASLVYSIMT--VHWGLPPPNLVVSVMGG-GGREKVKSWVRDVLRQGLVLAAQSTGAWIMTGGLKEGVGHCVGEAVRDHVAAASSPSQSKVVAIGVAPWGLVANRQQL---VNAQGSFPARYYIQNTSHD---SCYLDNNYQAFLLVDDGSVGHRGGETNFITNMEDYISNQRTGIWGSGNIEIPVLCMLISGEASVLKRMDMSLKKATPWLVLDGSGPAADMISELLDDLSPAASPADGDVRDSSTAELRNRTKEIIKKHFPAEKVLEKLVDRALSIYQNRALITVFHGDQDSPDDFDTVLLKALVRACRQMSSDASEYTEELKLAVAWNRVDIAKSELFNGDIQWQ---YEALKDCMTDALVNNKPQFVRVFIENGLNILEYLTYQRLESLYQSLSDSSL--AYSLLQKWLRERHSLVAMSPHSPDSPEKKSKKSLKVPPNVRELSLYEVSRLLGELFGGMCQPFYYSVLDLDPGASNRKAAKQLNKLQADGAYGKRSCNHPWAS--LFIWAVLQNRSEMAIYFWEMAGESVLSALCACKMLRELCKL-----ENETETKLSIKELAQKFETLAHDTFSACYQSSESRSFTLLIRTSPVWGGVTCLQMAMAADARLFFSHDGVQTLLSQIWWGDMNSRTEVWKLVAS-----FLMPPLI 745 HSP 2 Score: 108.612 bits (270), Expect = 2.322e-23 Identity = 110/343 (32.07%), Postives = 172/343 (50.15%), Query Frame = 3
Query: 2418 FYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDV----AGPCNGTDCIVSSGT-----------VLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFE 3401
F+ AP+ F ++L Y +FL +FAY LVE KP E +Y +V T EE RQ F G Y WNKFD I++F +V R P + + R + + +F +R + + +NK +GPKII++ M++D+ FFL ++++ YG+ ++L Y +F+ + Y P+ +G++ L+ D PC ++ G VLI +V+LL+TNVLL+NLLIAMF YTF+++QE S+ W F R L+ E++ +P PP IF H I K K+ + + MLE + K+ +LN +E
Sbjct: 850 FWFAPVTSFLGNVLMYFLFLFLFAYVLLVEFKPPPPEGPAH---IEYLLYFWVFTLVCEEFRQSFFVGNTGLCQSMSLYIQDMWNKFDLTAIMLFCVGLVCRM-FPWS-YEFGRSVLCVDYMVFTLRLIHIFAINKQLGPKIIIVGKMVKDVFFFLFFLGVWLMAYGVANQALLYSYDPRPYWVFRRVFYRPYLHIYGQIPLDEIDAYRRGDKPCTNNVTLIHEGAEPCPQSEANWLVLILLSVYLLVTNVLLLNLLIAMFSYTFSKVQEHSDVHWKFQRYNLIVEYHSRPCLAPPFIIFSHLHLFI----KRSIRKVPSTKIKHFMLE-LRGRKASRLNTWE 1182
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Cavefish
Match: trpm4a (transient receptor potential cation channel subfamily M member 4 [Source:NCBI gene;Acc:103041664]) HSP 1 Score: 204.142 bits (518), Expect = 8.076e-53 Identity = 183/777 (23.55%), Postives = 344/777 (44.27%), Query Frame = 3
Query: 102 KNTKSEITIKNGFE--DQIQEFINKKFNTRTCYKYKEKSK---DICHCNRHLNHHTNKSNSP-------EEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISE-FRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF---------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVM------GLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMI-----VGADKS-MKRTLKLCIRFNCSNIADKIVF-SDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNR---------------LFDAGDIIAKLSGNLLNNQYSQLFD-KPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLT--DASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMI 2273
++ K E + +NG ++ Q ++ K + C + E S+ D C C H++ + +W + +T+ FG ++F+G H H F+R C D VY +MT +W +P P +++S+ GG E + + + +QGL+ + W++ GL G+ V EA+ + + +V IGV+ WG V N Q+L +NA+ + +NTS D LD Y FL DDG+ E F+ E+++ Q G ++ +L G L ++K P +V+ GSG A+MISE++ P+ L N+ I + +E+ + + +Y N V + D+ FD +L+A++ + +D S LKL + +N +IA +F D ++ E +++ +L +NKP+FV +F+EN ++ ++ L+ LY+ DS LL R+ S ++ S + + + L++ ++ +L G + Y + D P + + W++ LF+WA+L R+++++ W ++ + SAL A +L+++ L +N + KL+ + ++K++ LA + Y S+S+++TLL+R+ W G+TCLQ+A+ + F +H ++ +++W GD++ WK++ + FLM +I
Sbjct: 3 QSEKEEESARNGSGKGEKDQSWVPKIIKKKVCTTFLEDSQSNGDRCQCGSERAAHSSSATGDFFGSAVVSQWDTAVHTSEYPTDAFGEVEFAG-AGRRHSH---FLRLSC----DTPASLVYSIMT--VHWGLPPPNLVVSVMGG-GGREKVKSWVRDVLRQGLVLAAQSTGAWIMTGGLKEGVGHCVGEAVRDHVAAASSPSQSKVVAIGVAPWGLVANRQQL---VNAQGSFPARYYIQNTSHD---SCYLDNNYQAFLLVDDGSVGHRGGETNFITNMEDYISNQRTGIWGSGNIEIPVLCMLISGEASVLKRMDMSLKKATPWLVLDGSGPAADMISELLDDLSPAASPADGDVRDSSTAELRNRTKEIIKKHFPAEKVLEKLVDRALSIYQNRALITVFHGDQDSPDDFDTVLLKALVRACRQMSSDASEYTEELKLAVAWNRVDIAKSELFNGDIQWQ---YEALKDCMTDALVNNKPQFVRVFIENGLNILEYLTYQRLESLYQSLSDSSL--AYSLLQKWLRERHSLVAMSPHSPDSPEKKSKKSLKVPPNVRELSLYEVSRLLGELFGGMCQPFYYSVLDLDPGASNRKAAKQLNKLQADGAYGKRSCNHPWAS--LFIWAVLQNRSEMAIYFWEMAGESVLSALCACKMLRELCKL-----ENETETKLSIKELAQKFETLAHDTFSACYQSSESRSFTLLIRTSPVWGGVTCLQMAMAADARLFFSHDGVQTLLSQIWWGDMNSRTEVWKLVAS-----FLMPPLI 745 HSP 2 Score: 108.612 bits (270), Expect = 2.156e-23 Identity = 110/343 (32.07%), Postives = 172/343 (50.15%), Query Frame = 3
Query: 2418 FYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDV----AGPCNGTDCIVSSGT-----------VLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFE 3401
F+ AP+ F ++L Y +FL +FAY LVE KP E +Y +V T EE RQ F G Y WNKFD I++F +V R P + + R + + +F +R + + +NK +GPKII++ M++D+ FFL ++++ YG+ ++L Y +F+ + Y P+ +G++ L+ D PC ++ G VLI +V+LL+TNVLL+NLLIAMF YTF+++QE S+ W F R L+ E++ +P PP IF H I K K+ + + MLE + K+ +LN +E
Sbjct: 850 FWFAPVTSFLGNVLMYFLFLFLFAYVLLVEFKPPPPEGPAH---IEYLLYFWVFTLVCEEFRQSFFVGNTGLCQSMSLYIQDMWNKFDLTAIMLFCVGLVCRM-FPWS-YEFGRSVLCVDYMVFTLRLIHIFAINKQLGPKIIIVGKMVKDVFFFLFFLGVWLMAYGVANQALLYSYDPRPYWVFRRVFYRPYLHIYGQIPLDEIDAYRRGDKPCTNNVTLIHEGAEPCPQSEANWLVLILLSVYLLVTNVLLLNLLIAMFSYTFSKVQEHSDVHWKFQRYNLIVEYHSRPCLAPPFIIFSHLHLFI----KRSIRKVPSTKIKHFMLE-LRGRKASRLNTWE 1182
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571]) HSP 1 Score: 193.356 bits (490), Expect = 2.600e-49 Identity = 155/582 (26.63%), Postives = 281/582 (48.28%), Query Frame = 3
Query: 1785 DVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKM------ADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTW-KIIITIPFSLFLMKL-------------------MIMPSFPRKGKNPKDVPD---AKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPC--NGTDCIVSSGTVLISF--AVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSR------CPKLIFEQENNLMLEHCKPSKSLKLNNFEQFCL 3413
D + +F + +L +WA+L R +S+ W+ + + AL A + + M +D+V ++ +L + S ++ LA ++ Q++ + + + LL L W+ TCL++A++ + F+ H+ + + +WM L+ +W K+I++I ++ L M M +NP D+ + N H+ ++ +S + ++ FY APIVKF + L Y+VFLM+++Y LV+L I Q WA I +Y+ T AIE+IR++F E K +F +N+ D + I++F RF N F+ R ++ +++ + +R + VN+ GP ++MI M+ ++ + + I + ++TYG+ +++ YPNSE L D+V+ P++ +GE+ DV N D + ++G L AV+L + +L++NLLIA F + Q+ S +W + R + ++ KP+ PPPL IFYH +S CK R PKL +E+ KL++FE+ C+
Sbjct: 583 DPETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVV-----DDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYKVILSILVPPAILALEYKSKAEMAHIPQSQDAHQMTMEDSEHNLQNPDDIQMDVFKETRINDHVEVKHETEVVTRSRRLPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKLP----IFPSPQEWAVI---LYIFTSAIEKIREMFMSEGGKISQKIKVWFSDYFNRSDFIAIVMFAVGFGLRFG-SGNVFIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYGEVYAYEIDVCANSTENNMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIFYHISSFLSFLCKRRKKDSAYGPKLFLTEEDQ-----------KKLHDFEEQCV 1140 HSP 2 Score: 117.087 bits (292), Expect = 7.084e-26 Identity = 113/434 (26.04%), Postives = 188/434 (43.32%), Query Frame = 3
Query: 174 FNTRTCYKYKEKSKDI--CHCNRHLNHHTN---------------KSNSP-EEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQ------ADGF-LVQILFEGGRRALLNAYKAIKDK--VPLVVIKGSGRVANMISEVM-------GLPSKNYKESIEF-IVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVF 1370
F R C SKD C C R + H ++ P EEWS N+T +G I F G H + K++R + +A R LM W + P ++IS++GG++N + + K+ +GLI W++ G++ G+ K V +A+ E H ++ IG++ WG ++N L IG ++V Y+ +L+ L+ F+ D+GT +Y EV E + Q G +V ++FEGG +L + +++ VP+VV +G+GR A+++S V GLP + +E I+ K T + + DA V F L+E N + V + + + D IL+A++ G D S L L + ++ +IA VF
Sbjct: 3 FTKRECVYILPVSKDPHRCCCGRLVRQHVGFTASLAMKYSDMKLGEAQPPHEEWSVENHTEQSPTDAYGIINFQGGS---HSYRAKYVRLSHDSRPEAILR----LMLKE--WQMELPKIVISVHGGIQNFD-LHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKE---HSSRSARKICTIGIAPWGVIENRNDL-------IGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDNGTVGKYGAEVNLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTEDDGGLP-----DGVETDIIATVKKTFNLS---QNDA-VHLFQT-LMECMKNKELITVFHVGSEDHQDIDVAILKALLKGTDASAFDQLVLTLAWDRVDIAKDHVF 406
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Sea Lamprey
Match: trpm2 (transient receptor potential cation channel, subfamily M, member 2 [Source:NCBI gene;Acc:799412]) HSP 1 Score: 265.388 bits (677), Expect = 2.396e-73 Identity = 280/1136 (24.65%), Postives = 501/1136 (44.10%), Query Frame = 3
Query: 141 EDQIQEFINKKFNTRTCYKYKEKS------KDICHCNRHLNHHTNKSN-SP----EEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAP---TWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDAL---YDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGFLVQILFEGGRRALLNAYKAIKDKVPLVVIKG--SGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVG--------------------ADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDS--------FEEFAMLYESDVDAHKFSWST--------------------QDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF-DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRF---SIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLE----NFDVAG-------------PCNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAF 3284
++ ++ +I++ + C Y E S + +C C + H N + P ++W + +T + FG I+F+G + KF+R + + +++LM +W++ P ++IS+ GG KN + + F+ GL + W+I G AG+ K V E++ +F + ++ IG++TWG + N + L I F E DE G+ L L + F+ D+GT QY E+ + E ++ Q G GG + KA+ ++G + R+ +M V + I I+++ + V E + ++ F+KQ + +D++ + I +A++ G A +S L+L + +N +IA +F+D + + G ++++ +L +N+PEF++LFVE+ + ++ A L+ LY P + LL L R +KS + R + K N +S L+ L+ R+ L DS F+ L S + T +DLF+WA+L R +L+ W K+ + +AL A+ +LK M V D++ + + Y+ LA ++ + Y + + LL+R L W G TCL +A + N F +HS ++ T++W G +S L TW++I+ I F L + +I +F + +L + P F+ API F +++SY +FL +FAY +++ + + W E +Y +VL+ +EE+RQVF D E G + Y WN+ D + +++F V+ R SI ++ F R + + +F +R M + VNK++GPKII+++ M++DI FFL + ++V+ YG+ + + N + +F+ +VY P+ FG+ FD P G D + T+L++ ++LL N+LL+NLLIAMF YTF +Q++++ +W F R +LV E++ +P PPL +F H +
Sbjct: 1 QEAVKAWISQNIKMKVCCWYIESSTAGGAARRVCECRHPRSEHANTALLKPTLLGQKWEPAKHTANEPTNAFGDIQFTGLG----QRLGKFVRVGNDTEPSV----LFKLMME--HWHLDVPNLLISVTGGAKNFH-LKPQLRTIFRHGLNKTARSTGIQGAWIITGGSYAGVMKYVGESVRDFALASGSKEGKIVAIGIATWGIIHNKEHL-------IDAQGKFPAE-YPMDEAGQGRLSCLDNNHSHFILVDNGTHGQYGVEIVLRARLEQYISTQHTG-------SGGE---CRSSKAVG-------VRGNCAARLWDMCVRV------RHCGKIVLIIMQAXSMV-----------VREINSSVI-----FEKQNIYFDVLICLFFLGRIISRALLTGTYACAMVVVCISASRGEANKAQESCDHQLRLALAWNRVDIATSEIFTDDRKWQTG--DLEQVMDAALLENRPEFISLFVEHGLILREYLTWARLESLYN------GAPASSLLHILLRRISE----GEKSPADPHRRWISTLPMAPKRM-----NHFS-LYHISLLIRELLGDSTSMLYGNKMSRFSKLSPSSKNTGSTKGGTSLEFKGQTYNEGQLYCPDPERDLFIWAVLLNRRELANFFWSQGKDCMAAALMASKLLKAM---VQEEDDSDRTSDMLAQADNYEQLAIGLLDECYKDDELRAQKLLIRQLHSWGGATCLSMAYHANNKSFFSHSGVQALLTQIWWGGMSVDLKTWRVILCIIFPLLIYTRII--TF------------------RWVLYAHTCTPTRWRN----------FWTAPITVFWANVVSYFIFLWLFAYVIIMDFQYTPD-------WPEYVLYAWVLSLILEELRQVFTDPEKAGQWKAAVRYIKDIWNRIDILALLLFTIGVICRLIPNSINESTFQAGRSVLCVDYMVFCLRLMHIFTVNKTLGPKIIIVKRMVKDIFFFLFLLGVWVVAYGVATQGILILNEQRLDWIFRGVVYQPYLLIFGQFPTRVDSTTFDTTSCTNNGINTSQPRCPVLGVDWL----TILLT-CLYLLFANILLLNLLIAMFNYTFQLVQDNTDTIWKFQRYELVNEYHSRPSLAPPLIVFSHLY 1015
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Sea Lamprey
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2]) HSP 1 Score: 203.756 bits (517), Expect = 1.097e-53 Identity = 248/1023 (24.24%), Postives = 460/1023 (44.97%), Query Frame = 3
Query: 456 WNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIG--TNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQA------DGF-LVQILFEGGRRALLNAYKAIKDK--VPLVVIKGSGRVANMISEVMGLPSKNYKESIEF-------IVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQI--VIYDMMDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQ--EMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGN-------------LLNNQYSQ---LFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQ-RKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTW-KIIITI--PFSLFLMKL---MIMPSFPR--------------KGKNPKDVPDAKNFHNKHLL-------------------DENAKAPPLKSEEITFIKAMSI--------FYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMI-CRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTD-----CIVSSGTVLISF--AVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGK 3242
W + P ++IS++GGL+N E + K+ F +GLI W+ G++ G+ V A+ E H ++ IG++ WG ++N L +G +++V Y+ S +L++L+ F+ DDGT +Y E + + E + A G +V ++ EGG ++ + + ++ VP+VV +G+GR A+ ++ KN ++ E IV K T G + L+E C +K++ V + + + D IL A++ G + S L L + ++ +IA VF ++ + LE + L +L ++ +FV L +EN + F+ L+ELY S D + +L LHR S+ + K L D G +I L G L +N Y Q D + ++ + L SD + F++ +L WA+L R ++M W+ + + AL A + + +A ++ L+ ++L A K+ LA ++ Q++ + + LL L W+ TCL++A++ F+ H+ + +WMG L+ +W K+I++I P S+ +++ M P+ + +D+P + + L + K EE +I+ + FY APIVKF + L+YI FLM+F Y LV+L Q++ S++ E ++ +Y+ AIE +R++F E K + G WN D++ I++F +V R Q+H +I + ++S+ + + +R + + VN+++GP I+MI M+ + I I ++++G+ +++ + ++ + L ++IV+ P++ FGE+ D N TD C ++G + F AV+L + ++++NLLIA F + + + S+KLW F R ++ K
Sbjct: 22 WQMELPRLLISVHGGLQNFE-LHPKLKQVFSKGLIKAALTTGAWIFTGGVNTGVVNHVGNALKE---HASRSSHKICTIGIAPWGVIENRGDL-------VGQDSHVVSPYQTLSNPLSKLNLLNSLHSHFILVDDGTVGKYGAEAQLRRELEKHIATVACRAGMGQGVPVVGLVAEGGPNVIVTVLEYLLEEPPVPVVVCEGTGRAAD----ILAFLHKNTDDTGELCDGLHDEIVGTIKKTFNFSHG-----QAMHLLQTLLE--CMRRKELITVFHTGSEDHSDVDLAILTALLKGTNFSSADQLNLALAWDRVDIAKNHVFVYGQHWMVRLEWARWRRPMLDALVMDRVDFVKLLIENGVSMHKFLTITRLEELYNTS-DHHQMSNLRIL--LHR--FSHLPPDYKIT------LIDVGLVIEFLMGGAFRSMYTRKRFRLLYHNLYGQHRASVDNTRQRKQKMSTASGVGVTLDGSDPECSCFAYPFNELLAWAVLMKRQRMAMFFWQHGEESLAKALVACKLYRSLAGEAKQSREDELKWKRLWCARVKFGQLALDLLDQSFRQDERMAMKLLTYELRNWSNFTCLKLAVSSRHRPFVAHTCTQMLLADMWMGRLNMRKNSWFKVILSILMPPSILMLEYKSKAEMSHIPQSEELHQMGQEEREHRAAATRDIPMQRCLSRRVFLRLLSFAIRILLLRTVGNGSAADGGESGHKEEEGIWIRPSGLSLSRRIYEFYHAPIVKFWFNTLAYIGFLMLFTYVVLVKL---QQLPSVQ----EWFVILYLFMSAIERVREIFMSEPGKFGQKIKVWLDGYWNINDSLGILLFFVAVALR---SQSHLLIEAKIVYSLDVIFWYVRLLDVFAVNQNVGPYIMMIGKMMWQQCMLMIIMAIVLLSFGVARQAILFKEADPSWYLARNIVFQPYWMIFGEVYAPEID-----NNTDDEYPPC--TTGAFITPFLQAVYLFVQYIIMVNLLIAFFNNIYLEAKNISDKLWKFHRYHFTMYYHQK 994
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Sea Lamprey
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2]) HSP 1 Score: 140.969 bits (354), Expect = 4.142e-34 Identity = 136/539 (25.23%), Postives = 260/539 (48.24%), Query Frame = 3
Query: 1782 SDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKK-------YQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTW-KIIITI--PFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFH---NKHLLDENAKAPPLKSEEITFIKAMSI--------FYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFD-----QEING--------AKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMI-CRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFD-----VAGPC-----NGTD-----CIVSSGTVLISF--AVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGK 3242
SD + F++ +L WA+L R ++M W+ + + AL A + + +A G+ + D+S++ + LA ++ Q++ + + LL L W+ TCL++A++ F+ H+ + +WMG L+ +W K+I++I P S+ +++ + +P ++ H N D K EE +I+ + FY APIVKF + L+YI FLM+F Y LV+L Q++ S++ E ++ +Y+ AIE +R+V D ++ G A K + G WN D++ I++F +V R Q+H +I + ++S+ + + +R + + VN+++GP I+MI M+ ++ + I I ++++G+ +++ + ++ + L ++IV+ P++ FGE+ D V C N TD C ++G + F AV+L + ++++NLLIA F + + + S+KLW F R ++ K
Sbjct: 458 SDPECSCFAYPFNELLAWAVLMKRQRMAMFFWQHGEESLAKALVACKLYRSLA------GEAKQSEAVEDSSEELKQYSTEFGQLALDLLDQSFRQDERMAMKLLTYELRNWSNFTCLKLAVSSRHRPFVAHTCTQMLLADMWMGRLNMRKNSWFKVILSILMPPSILMLEY-------KSKAEMSHIPQSEELHQMGNGSAADGGESGH--KEEEGIWIRPSGLSLSRRIYEFYHAPIVKFWFNTLAYIGFLMLFTYVVLVKL---QQLPSVQ----EWFVILYLFMSAIERVREVSDGARETRKAAGLRSDSEASAHRKIKVWLDGYWNINDSLGILLFFVAVALR---SQSHLLIEAKIVYSLDVIFWYVRLLDVFAVNQNVGPYIMMIGKMMANMFSIVIIMAIVLLSFGVARQAILFKEADPSWYLARNIVFQPYWMIFGEVYAPEIDGICVAVLAACENIMKNNTDDEYPPC--TTGAFITPFLQAVYLFVQYIIMVNLLIAFFNNIYLEAKNISDKLWKFHRYHFTMYYHQK 969 HSP 2 Score: 80.1073 bits (196), Expect = 2.390e-15 Identity = 55/217 (25.35%), Postives = 105/217 (48.39%), Query Frame = 3
Query: 456 WNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIG--TNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQ-----------ADGF-LVQILFEGGRRALLNAYKAIKDK--VPLVVIKGSGRVANMIS 1058
W + P ++IS++GGL+N E + K+ F +GLI W+ G++ G+ V A+ E H ++ IG++ WG ++N L +G +++V Y+ S +L++L+ F+ DDGT +Y E + + E + Q G +V ++ EGG ++ + + ++ VP+VV +G+GR A++++
Sbjct: 21 WQMELPRLLISVHGGLQNFE-LHPKLKQVFSKGLIKAALTTGAWIFTGGVNTGVVNHVGNALKE---HASRSSHKICTIGIAPWGVIENRGDL-------VGQDSHVVSPYQTLSNPLSKLNLLNSLHSHFILVDDGTVGKYGAEAQLRRELEKHIALQKIHTLACRAGMGQGVPVVGLVAEGGPNVIVTVLEYLLEEPPVPVVVCEGTGRAADILA 226
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Nematostella
Match: EDO30135 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1N0]) HSP 1 Score: 327.405 bits (838), Expect = 1.540e-92 Identity = 306/1201 (25.48%), Postives = 544/1201 (45.30%), Query Frame = 3
Query: 132 NGFEDQIQEFINKKFNTRTCYKYKEKSKDI--CHCNRHLNHHTNKS----NSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISE--FRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEV-------EFLLKFENFVKKQADGF---LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEE--DAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMS--FDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELY-EISFDSEKCPCAELLCDLHRDTKSYFKLN---KKSNSTEQNRLFD---AGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQ---------------DLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDN---NLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLM-IMP---------------------SFPRKGKNPKDVPDAKNFHNKHLL----DENAKAPPLKSEE-------------------------ITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYC---NLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPN----SEFNT-LLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVSSGTVL--ISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAF---RIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFE 3401
N + +I + F+ R C ++ KS D+ C C R H+ ++ EEW+ ++ TT +G I F GY + ++R D DA V LM WN+ P ++IS+ GG K+ + ++ F++GLI K W+I G + G+ K V EA+ E F + QV++IG++TWG V L N K ++ E T + +LD + F DDGTE +Y E+ E ++K + + +A +V ++ EGG + Y+ IK KVP VVI GSGR A+++ K + V++ + ++ E A+ + T +++ +K I +Y + D +S D IL+A++ S L L + +N ++A +F++ + + E + L +L D+K A EL+ + + ++LC L+ + + +K Q + D G++I +L G++ + Y +D F E A E V ++ S D+FLWA+L R +L+ +LW + + +AL A+ +LK+MA + DN ++ L D ++ +++ A ++ + +N++++ + TLLVR L ++ +T L++A++ +F+ H++C+ T++WMG ++ WK+++ + + + ++ +P S + K D P + +K DE A+ EE + F + FY AP KF +++ Y+ F+ ++AY N P + + I EI +Y +V T IEEIRQ+ + K K YF TWN D + +FI +++ RF F R + S+ + F++RS+Q + VN+ +GPK++MI+ M++D+ F+ I +F I YGI ++ +P+ + NT + +V P++Q +GEL L+ P + + G L + A++++ TN+LL+NLLIA+F YTF ++QEDS+K+W F R LVQE++ +P+F PPL + H R + C+ P + M P++ +++N+E
Sbjct: 26 NQLSQSKKSWIARNFSRRECIRFVPKSHDVSRCKCGRPRERHSQQALESGQGSEEWNVASCTTKHPTNAYGEIDFEGYGG---QKRAPYLRMS--HDTDANL--VITLMLKR--WNLEIPNLVISVTGGAKSF-VLKPRLREMFRRGLIKAAKTTGAWIITGGTNTGVMKHVGEAVKEQQLMFGSDT---QVNVIGIATWGIVDKQSDLISEKNGKYPA--LYSMEPTPGHQGA--MLDPNHSHFFLVDDGTEGKYGVEIGMRSRIEEAIMKVKTDSRSEAGSIGVPVVLLVLEGGPNTVATMYELIKKKVPAVVIDGSGRAASVVGFAYNHTIKRNVDGQTINVIDPQYEDEVRAKVVEVFGAKGADKTYSMIKDVLEDEKMISVYSL-DGEISQDIDLAILKALLKANRSSPVAQLNLALAWNRIDLAKSDIFTEEQ--QWTTETLSAAMLTALLDDK--------------------AEFAELFLQNGLSMREFLSLDILCKLYAEVPGNTTIKPLLQKEMGKRQVKTIDMDVVGEVIEELMGDMFESYY---------RKD--GHYFGELASYAEGLVLKNRKSSKDLLANINRIDPLPTPYLDVFLWAVLCNRRELARVLWEAGREPMAAALMASRLLKRMASRA--QEDNTITDISSDLYDHARLFEERAVGVLDECFNENETLSQTLLVRELDHYSRMTALELAVSAESQDFIAHTSCQVLLTRLWMGTMAMNTRWWKVLVCLYLPVLIFPIIYFVPDEQHERQAAEREHQKSLNQKSSKVKSHKEKNDAPVVPVYRSKEEKAVSNDEEARVGTENEEEDFQLEDYIPEIREDDSMEVIMRNKKLGFCDRIMHFYSAPFSKFVGNVVGYLAFIFLYAYVVLFNFPRFDPAKTLGGIHPT--EIVLYFWVFTILIEEIRQLAAKPPKYIKDKVSVYFSDTWNFVDIFSLTVFIIAIILRFFTNSRIFTASRIILSLDIIFFIVRSLQIFSVNRLLGPKLVMIQKMMQDLAQFIIILAVFTIAYGIALHAVMFPSPGIYARNNTWVTITSVVQYPYWQMYGELFLDEIQGEKPKEFGE-VDPDGRWLSPLLLAIYMVFTNILLLNLLIAIFNYTFERVQEDSDKVWKFQRYDLVQEYHSRPVFAPPLVLLGHILIFIRWVWRMCRCGHPP-----RGSTMKIGLSPAEMEQMDNWE 1165
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Nematostella
Match: EDO47658 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLT7]) HSP 1 Score: 146.747 bits (369), Expect = 1.437e-35 Identity = 137/487 (28.13%), Postives = 244/487 (50.10%), Query Frame = 3
Query: 1977 RKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDL-SPFLPTWKIIITIPFSLFLMKLMI-----MPSFPRKGKNPKD--VPDAKNFHNK----------HLLD-----ENAKAPPLKSEEITFIKAMSI------FYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLS---YFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVSS------GTVLIS--FAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRC 3317
R + D S+++ D+A ++ + Y + LL+ W G T L +A+ EF+ HS C+ T++WMG L + + + K+++ I F + L M P + D PD +H++ +L D +N K+ + E I I+ + + FY API KF +L+ Y++FL+VF++ L+EL P+ I+ E + +V + EE+RQV + IN F + WN D +++F +V R + I ++S+ + +++IR + + V+K +GP ++MI M D+++FL I V+F++ YG+ +++ +P+ + + L I + P+FQ +GEL +E+ D + N + S+ G L++ A +LL+ N+LL+NLLIA+F TF+++Q +S ++W F R LV E+ +P PP + HA + K C
Sbjct: 587 RDMLD-SREFYDIALGLLDECYKANDVLAQRLLIYHPVYWGGRTSLSLAVASRHEEFVAHSCCQKKLTEIWMGALKTGYNGSLKVLLGILFPPLIFALEFRSREEMQRVPTTDDDSADDLPPDFDPYHHREPGSAQYNDGYLGDGVAFVKNRKSSGNEEEPIVEIRLLGLGKRIIGFYNAPITKFWSNLIVYLLFLVVFSHVILIELPPVPSIE-------EWVLIGFVFSLCAEEVRQV--RVINVWNFSFFESSDWASNVWNLCDGFAMVLFFLAVGLRLN--PGTLRIGHLVYSLDIMLWIIRLLDIFSVSKDLGPYVVMIGRMTIDMMYFLVIMVVFLLAYGVAQQAILFPHEKPSWELITKIFFRPYFQVYGELFIEDVDYS--SNSRETAFSTPKFDEYGGRLVTVIMAFYLLVANILLLNLLIAIFNNTFSEVQANSNQIWKFQRFSLVMEYRQRPRLVPPFILIAHAHGLAKAIWKRAC 1059 HSP 2 Score: 122.479 bits (306), Expect = 4.415e-28 Identity = 101/393 (25.70%), Postives = 184/393 (46.82%), Query Frame = 3
Query: 276 EWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRF--HQEDIKD---QVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFV--KKQADGF----LVQILFEGGRRALLNAYKAIK--DKVPLVVIKGSGRVANMISEVMGL--PSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIV-IYDMMDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFS-DPKYDELGLE 1403
+W + +T FG ++F G P K+IR + D + R + W + P ++IS+ GG KN +S K+ ++GL+ + WVI G + G+ + V EA+ E +K+ QV LIG+++WG V + + L +N K+ V Y+ TS + LD + F+ D+GT+ +Y E+ F EN + KK A F +V ++ EGG + +++ VP+V+ +GSGR A++++ PS + +V ++ +I E + + + Y + C K++ V I+ + D + DK IL+A++ ++ L L + ++ ++IA +F+ D K++ LE
Sbjct: 5 KWVPTRHTVTLPTDAFGELEFQG-AGQPSR--AKYIRLAHDTDPELVLRLL------CGEWALDLPKLLISVTGGAKNF-ILSPKIKRVLREGLLKAAQTTGAWVITGGTNTGVMRHVGEAVKGHTVMSRGEQLKNTAHQVHLIGIASWGIVDHKEML---VNPKVE---VVPYQMTSSMQSRGACLDNNHSHFILVDNGTDGEYGGEISFRASLENLIASKKMAQKFHGVPVVLLVLEGGPNTIRTVLESVSRCPAVPVVIAEGSGRAADILAFAHRFIAPSNGEMSGVADVVEHRQLLHKIEKSFAECSPEDRLSIYQNVLKCVAKREFVTIFCVDDGGLEVDKAILRALLKSQHSQLEDQLSLALVWDRADIAKTEIFTEDQKWEVPMLE 381
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Medaka
Match: trpm2 (transient receptor potential cation channel subfamily M member 2 [Source:NCBI gene;Acc:101170060]) HSP 1 Score: 279.256 bits (713), Expect = 1.506e-76 Identity = 288/1128 (25.53%), Postives = 517/1128 (45.83%), Query Frame = 3
Query: 159 FINKKFNTRTCYKY-KEKSKDICHCNRHLNHHTNKSNSPEE-----WSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKV-ILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF--------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMM--------DANMSFDKKILQAMIVGADKS-------MKRTLKLCIRFNCSNIADKIVFSDPKYDEL--GLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEK-CPCAELLCDLHRDTKSYF---KLNKKSNSTEQNRLFDAGDI----IAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSW------STQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIM----PSFPRKGKNPKDVPDAKNF-HNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF-DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVA----GPC--NGTDCIVSSGTVL--------------ISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH---AFRIISLPCKSRC 3317
++ + N + C + K S++IC C H ++ PE+ W+ + FG I+F G + K+ R E + +Y+L+T W++ P ++IS+ GG KN ++ H + F +GLI V + W+I G +AG+ K V +A+ ++ I+ Q+ IGV+TWG + N + L +N + ++ + TS+ G++ LD + FL DDGT Y E+E E + + G +V ++ EGG L + A+K+ P V+ +G+GR+A++I++V GLP + ++ ++E E ++FT V + + IV + D++ D IL+A++ + S K L+L + +N +IA +F++ D L ++ Q MF +L NKP+ + L E K E LC+L+R+ S KL K+ +S + L D+ +I ++ +LL N ++ P +E+ + S E+ ++ + A + + ++ D+FLWA+L DL+ I W ++ I +AL A ILKK+A D ++ + + Y++ A + ++ YN + + LLV W G T L +A+ F+ S +++ T+VW G+LS +++I + F + + F ++ K + + K N H AP + ++ + Y +P VKF +++SY FL +FA +++ + E+ +Y++V + EE RQ+F + + G K K Y WN D + I++F+ + R + F + + I +F +R M + +++++GPKII++R M++D+ FF+ + I+V+ YG+ + + N +F+ +Y P+ FG EN A C NGTD + +L V+LL N+LL+NLLIA+F +TF ++Q++++++W F R +L++E++ +P PPP IF H R I L CKS C
Sbjct: 33 WMKQNINKKECALFQKGPSEEICKCGYSKEAHNVEAIKPEDFVGETWNKHRHVLDVPTNAFGEIQFDGL----QQTTAKYARVSSETSPEV----LYDLLTEQ--WHLLPPNLLISVTGGAKNF-NLKPHLRNMFHRGLIKVAQTTGAWIITGGTNAGVMKHVGQAVRDYSL-SNSIQGQIVAIGVATWGVIHNREAL---INEEGCFPALYMTDKTSQ---GRLSCLDKNHTHFLLVDDGTHGHYGVEIELRTCLEKCISGKQLGKKDSSVTIPVVCVVLEGGPGTLNTIFNAMKNGTPCVIFEGTGRIADVIAQVSGLPLQQITITLIHQLMEKFF----------GQEYKKFTELSVIEWTKKIQDIVRMSHLLTIFRVTEDSHGDVDVAILKALLKASRSSETLTLDCWKTQLELAVAWNRVDIAKTEIFTE---DSLWSSADLHQAMF-SALVGNKPQ-------------------FVTLLLENGMSLRKFLQNEETLCNLYREMPSCIFLRKLAKRVHS--KADLVDSNNITLTHVSDEVRHLLGNATRHIY-PPYVEQRYCM-SAEDLSLSLSKNNGAPRPAGEVAQRDASSDVFLWAVLQNNRDLAEIAWEQCQDSICAALAATRILKKLAG---GESDAEEAEEMLNQASHYEEHAIGVFSECYNTDEERALKLLVHVSNFWGGTTSLWLALKAEDKRFVALSGVQAFMTRVWCGELSVDNHILRVLICMLFFPLIYTGFLAFRHDELFQKEAKKQEAMKKVKRVTGNTHGAQSLGSAP---DKPLSCWDRLVSLYGSPQVKFYWNIVSYFFFLNLFAGVLMMDFHATPSV-------PELLLYVWVFSLVCEEFRQLFCNSDGFGFKIKAKLYITDLWNILDVLSILLFLLGLAFRLT--SELFYAGKIVLCIDFVVFCLRLMAIFTISQTLGPKIIIVRRMMKDLFFFMFLLSIWVVAYGVAKQGILIHNDTRLDWIFRGAIYEPYLIIFGNFP-ENLAEAKFSLDSCSMNGTDPLKPKCPILNENHAPVFPEWLTITMLCVYLLFANILLLNLLIAIFNFTFQEVQDNTDRIWKFQRYELIKEYHSRPAAPPPFIIFSHLSLLIRSIWL-CKSHC 1088
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Medaka
Match: trpm2 (transient receptor potential cation channel subfamily M member 2 [Source:NCBI gene;Acc:101170060]) HSP 1 Score: 278.87 bits (712), Expect = 2.464e-76 Identity = 288/1128 (25.53%), Postives = 517/1128 (45.83%), Query Frame = 3
Query: 159 FINKKFNTRTCYKY-KEKSKDICHCNRHLNHHTNKSNSPEE-----WSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKV-ILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF--------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMM--------DANMSFDKKILQAMIVGADKS-------MKRTLKLCIRFNCSNIADKIVFSDPKYDEL--GLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEK-CPCAELLCDLHRDTKSYF---KLNKKSNSTEQNRLFDAGDI----IAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSW------STQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIM----PSFPRKGKNPKDVPDAKNF-HNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF-DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVA----GPC--NGTDCIVSSGTVL--------------ISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH---AFRIISLPCKSRC 3317
++ + N + C + K S++IC C H ++ PE+ W+ + FG I+F G + K+ R E + +Y+L+T W++ P ++IS+ GG KN ++ H + F +GLI V + W+I G +AG+ K V +A+ ++ I+ Q+ IGV+TWG + N + L +N + ++ + TS+ G++ LD + FL DDGT Y E+E E + + G +V ++ EGG L + A+K+ P V+ +G+GR+A++I++V GLP + ++ ++E E ++FT V + + IV + D++ D IL+A++ + S K L+L + +N +IA +F++ D L ++ Q MF +L NKP+ + L E K E LC+L+R+ S KL K+ +S + L D+ +I ++ +LL N ++ P +E+ + S E+ ++ + A + + ++ D+FLWA+L DL+ I W ++ I +AL A ILKK+A D ++ + + Y++ A + ++ YN + + LLV W G T L +A+ F+ S +++ T+VW G+LS +++I + F + + F ++ K + + K N H AP + ++ + Y +P VKF +++SY FL +FA +++ + E+ +Y++V + EE RQ+F + + G K K Y WN D + I++F+ + R + F + + I +F +R M + +++++GPKII++R M++D+ FF+ + I+V+ YG+ + + N +F+ +Y P+ FG EN A C NGTD + +L V+LL N+LL+NLLIA+F +TF ++Q++++++W F R +L++E++ +P PPP IF H R I L CKS C
Sbjct: 33 WMKQNINKKECALFQKGPSEEICKCGYSKEAHNVEAIKPEDFVGETWNKHRHVLDVPTNAFGEIQFDGL----QQTTAKYARVSSETSPEV----LYDLLTEQ--WHLLPPNLLISVTGGAKNF-NLKPHLRNMFHRGLIKVAQTTGAWIITGGTNAGVMKHVGQAVRDYSL-SNSIQGQIVAIGVATWGVIHNREAL---INEEGCFPALYMTDKTSQ---GRLSCLDKNHTHFLLVDDGTHGHYGVEIELRTCLEKCISGKQLGKKDSSVTIPVVCVVLEGGPGTLNTIFNAMKNGTPCVIFEGTGRIADVIAQVSGLPLQQITITLIHQLMEKFF----------GQEYKKFTELSVIEWTKKIQDIVRMSHLLTIFRVTEDSHGDVDVAILKALLKASRSSETLTLDCWKTQLELAVAWNRVDIAKTEIFTE---DSLWSSADLHQAMF-SALVGNKPQ-------------------FVTLLLENGMSLRKFLQNEETLCNLYREMPSCIFLRKLAKRVHS--KADLVDSNNITLTHVSDEVRHLLGNATRHIY-PPYVEQRYCM-SAEDLSLSLSKNNGAPRPAGEVAQRDASSDVFLWAVLQNNRDLAEIAWEQCQDSICAALAATRILKKLAG---GESDAEEAEEMLNQASHYEEHAIGVFSECYNTDEERALKLLVHVSNFWGGTTSLWLALKAEDKRFVALSGVQAFMTRVWCGELSVDNHILRVLICMLFFPLIYTGFLAFRHDELFQKEAKKQEAMKKVKRVTGNTHGAQSLGSAP---DKPLSCWDRLVSLYGSPQVKFYWNIVSYFFFLNLFAGVLMMDFHATPSV-------PELLLYVWVFSLVCEEFRQLFCNSDGFGFKIKAKLYITDLWNILDVLSILLFLLGLAFRLT--SELFYAGKIVLCIDFVVFCLRLMAIFTISQTLGPKIIIVRRMMKDLFFFMFLLSIWVVAYGVAKQGILIHNDTRLDWIFRGAIYEPYLIIFGNFP-ENLAEAKFSLDSCSMNGTDPLKPKCPILNENHAPVFPEWLTITMLCVYLLFANILLLNLLIAIFNFTFQEVQDNTDRIWKFQRYELIKEYHSRPAAPPPFIIFSHLSLLIRSIWL-CKSHC 1088
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Medaka
Match: hrc (transient receptor potential cation channel subfamily M member 4 [Source:NCBI gene;Acc:101158642]) HSP 1 Score: 247.284 bits (630), Expect = 1.669e-66 Identity = 262/1148 (22.82%), Postives = 507/1148 (44.16%), Query Frame = 3
Query: 153 QEFINKKFNTRTCYKYKEKS---KDICHCNRHLNHHTNKSNSP-------EEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIK-DQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF--------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVM---------GLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMS-FDKKILQAMIVGA-------DKSMKRTLKLCIRFNCSNIADKIVF-SDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDL--------HRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKL-----SG--NLLNNQYSQLFDKPLIERDFLTD---SFEEFAMLY--ESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMI----------------------MPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEIT--------FIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVW----AEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAG----PCNGTDCIVSSGT-----------VLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
+ +I R C + E S +C C + H ++ W +++ +G ++F+G H + F+R + ++Y LMT W++P P +++S+ GG ++ S+ N ++ ++GL+ ++A W+I G G+ K V EA+ + ++V +G+++WG V N ++L +N + + N+ +D LD Y FL DDG+ + E+ F K E+ + Q G ++ +L G L ++K +P +V+ GSG +A +S+V+ PS+ + + L+ ++ ++ + E ++ + +Y N K I +Y+ ++ FDK +L+A++ + D L+L + +N +IA +F D + + L ++ +L ++KP+FV LF EN F++ +++ L++LY+ P LL L H T + + +S Q + + + K+ SG ++L + Q F ++E + + ++ A L ES + + LF+WA+L R +++ W ++ + AL +L++M+ L + + L + ++ +++LA I + Y+ +++ +TLL++ W G TCLQ+ + G+ F +H +S +++W GD+ WK+++T + +I + S G PD K P + ++ + F+ AP+ F ++L Y +FL++FAY LV+ KP + W +E +Y +V T EEIR+ + + SY WNK D V I +FI ++ R + + R + + +F +R + + ++K +GPKII++ M++D+ FFL +++I YG+ ++L Y +F+ + Y P+ FG++ +E D C ++ SG+ V++ ++LL+TN++LINLLIA+F +TF+++Q +S+ W F R L+ ++ +P PP I H
Sbjct: 20 KSWIPSIIKKRVCTTFVEDSVSDGKMCQCGKPKVEHPPQAIGDYFSAAIVNYWDSVRHSSELPTDAYGELQFAGASKR-HSY---FLRLSWGTNPS----TIYNLMTVQ--WSLPSPNLVVSVVGG-ESQASVKNWVREVIRKGLVKSSQRAGAWIITEGFREGVGKCVGEAVRDHATAASSGSFNKVVAVGIASWGLVYNKEQL---INPEGSYPAKYDIRNSPKDS---CCLDNNYQAFLLVDDGSVGRKGGEISFRAKLEDHISHQPTGIQESGINVPVLCMLISGDTSMLKRVEISLKKSLPWLVLAGSGGLAEFLSDVVENLSSSPVVQTPSEADGDLSPIVDLKERVADRVKKYFPNEKETDKVVELTLSIYQN-KDLITVYNGTQERLNDFDKVLLKALVRASKQRVSVDDSPYIEELRLAVTWNRVDIARSELFNGDILWKDKDL---KDSMTNALINDKPQFVRLFTENGFNIRSYLTYKKLEKLYQ------SVPSGTLLYQLLERRLLIRHGITALSPAHDSQPDSPNQPKESNQCQPVMKVTLFEVSGVLDMLLDDVCQPFYYDVLELGHFSSRRRALKQAAKLLVGESKYREERCVYPWASLFIWAILQRRNEMATFFWEMAGESVLCALSGCKMLREMSKL---ETETEGKLSLKEMAQSFENLAHDIFSSCYHSDENRAFTLLIKKSPVWGGTTCLQMGMGGDTRLFFSHDGVQSLLSQIWWGDMKRNTEVWKLLLTFFCPILCYTSLISFRGQEEQDKPEEEEGKPNEELLDSNYDYGTTVYSYPDLKQNEADGQGPTTPSTPMINDKDPPFRPPRRPFIVSRWRQFWFAPVTSFLGNVLMYFLFLVLFAYVLLVDFKP-------QPPWGPAVSEYVLYFWVFTIVCEEIRETAFLGTRNWRQRLRSYIQDVWNKIDIVAITLFIVGLICRMY--ERSYEFGREVLCVDYMVFTLRLIHIFAIHKQLGPKIIIVGKMMKDVFFFLFFLGVWLIAYGVANQALIYSYDSNPDRIFRRVFYRPYLHIFGQIPVEEIDSGKNWDLECTNNMTMIDSGSEPCRVEHSNWVVVVLLIIYLLVTNIVLINLLIAIFSHTFSEVQANSDIYWKFQRYNLIVTYHFRPSLAPPFIIISH 1128
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Medaka
Match: trpm5 (transient receptor potential cation channel subfamily M member 5 [Source:NCBI gene;Acc:101161300]) HSP 1 Score: 213.001 bits (541), Expect = 9.342e-56 Identity = 238/989 (24.06%), Postives = 434/989 (43.88%), Query Frame = 3
Query: 426 VYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVI-LDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF--------LVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRT------LKLCIRFNCSNIADKIVF-SDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNS-----TEQNR----LFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLD-ENAKAPPLKSEEI-------TFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF--DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAG---PCNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
+Y+++T W + P +++++ GG + + + ++GL+ + W++ +GL GI K + +A+ + +V IG++ W + N + L L+AK+ +V+ ++ G V LD + F+ ++ + E +K + Q G+ V L G +L +I + P +++ GSG VA+++ +M + E + L A++ + L++ + + ++D D IL+A++ + LKL + +N +IA +F D ++ LE E+ + +L ++KP+FV LFV+N ++ F+ L+ELY SEK LL + + + + +EQ + LF+ +AK+ + L++ + K E+ F+ L E + + + W +DLFLWA+L R ++ W + + +AL ILK+MA L + R + +A KY+ A + + Y+ S+ + Y LLVR W+ T L +A + F H ++ TK+W G ++ K+++ S F L+ + + K F LD E A L+S I F++ F+ AP+ F +++ Y FL +F Y L++ K + + EI +Y +V T +EEIRQ F D+E+N K KF Y WNK D V I++F+ V R + + R + +I +F +R + + ++K +GPKII++ M++D+ FFL +++I YG+ ++L +PN +F+ +Y P+ FG++ LE DV G PC + + ++I +V A G +Q +++ W F R L+ E+Y +P PP I H
Sbjct: 71 IYQMLTQE--WGLSPPHLVVAVVGG-DELAQMKPWLRDTLRKGLVKAAQSTGAWILTNGLRFGITKHLGQAVRDHSLASTSSTVRVVAIGIAPWNMIHNREAL---LSAKVDEPVVYTPQDLPH---GSVYSLDNNHSHFVLVEEDPARP-GATSEMRVKLLKHISLQRTGYGGAGSFEIPVLCLLVHGEPKILKV--SIANSTPWLILAGSGGVADILVTLMNRGCWDTDSVHELL-------LDTFPNAHHSADISNWVK-LIQKILDHGHLLTVHDPEQETSELDTVILKALVKACKSQSQEAQDFLDELKLAVAWNRVDIAKSDIFNGDVEWKACDLE---EVMMDALINDKPDFVRLFVDNGVNLGEFLTYGRLQELYWSV--SEKSLLHNLLLKKYDEKQLLLGAARTPGPPGHYPSEQGKPRFTLFE----VAKVLKDFLHDSCKGFYQKVPTEKPPKGRLFQSQKNLPELE-ELCEHPW--RDLFLWAVLQNRQQMANYFWAMGPEAVAAALAGCKILKEMARL---ESEAESARSMKEA--KYEQFALDVFGECYSNSEDRAYALLVRRTHCWSKSTVLNLATEADAKSFFAHDGVQALLTKIWWGAMTTDTAISKLVV----SFFCPPLIWTNLIKFSDEELDNRSSNKQFVELDSLDTEKALIFLLRSILICASVWWRFFLRRWRRFWSAPVTVFLGNVIMYFAFLFLFTYVLLLDFKAPPQGPGV----PEIMLYFWVFTLVLEEIRQSFFTDEEMNIIK-KFKLYVEDNWNKCDMVAILLFVVGVSCRMA--AGTYEAGRTVLAIDFMVFTLRLIHIFAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLIAYGVATQALLHPNDPRIDWVFRRALYRPYLHIFGQIPLEEIDVMGLLPPCPN----IYANWLVILLSV------------RAADLGSRTKVVQGNTDIFWKFQRYNLIVEYYSRPALAPPFIIISH 995
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Medaka
Match: trpm5 (transient receptor potential cation channel subfamily M member 5 [Source:NCBI gene;Acc:101161300]) HSP 1 Score: 200.29 bits (508), Expect = 9.837e-52 Identity = 248/996 (24.90%), Postives = 454/996 (45.58%), Query Frame = 3
Query: 426 VYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVI-LDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGF--------LVQILFEGGRRAL---LNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRT-----LKLCIRFNCSNIADKIVF-SDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNS-----TEQNR----LFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACR-SYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVF--DQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGP-CNGTD------------C--IVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYH 3278
+Y+++T W + P +++++ GG + + + ++GL+ ++ W++ +GL GI K + +A+ + +V IG++ W + N + L L+AK +V+ ++ G V LD + F+ ++ + E +K + Q G+ ++ +L G + L YK I + P +++ GSG VA+++ +M + E + L A++ + L++ + + ++D D IL+A++ +S + LKL + +N +IA +F D ++ LE E+ + +L ++KP+FV LFV+N ++ F+ L+ELY SEK LL + + + + +EQ + LF+ +AK+ + L++ + K E+ F+ L E + + + W +DLFLWA+L R ++ W + + +AL ILK+MA L + R + +A KY+ A + + Y+ S+ + Y LLVR W+ T L +A + F H + + TK+W G ++ K++++ + +I F D+ + +L ++ + F++ F+ AP+ F +++ Y FL +F Y L++ K + + EI +Y +V T +EEIRQ F D+E+N K KF Y WNK D V I++F+ V + + R + +I +F +R + + ++K +GPKII++ M++D+ FFL +++I YG+ ++L +PN +F+ +Y P+ FG++ LE D P N TD C I ++ V++ +FLL+TNVLL+NLLIAMF YTF +Q +++ W F R L+ E+Y +P PP I H
Sbjct: 64 IYQMLTQE--WGLSPPHLVVAVVGG-DELAQMKPWLRDTLRKGLVKA-AQSTAWILTNGLRFGITKHLGQAVRDHSLASTSSTVRVVAIGIAPWNMIHNREAL---LSAK-DEPVVYTPQDLPH---GSVYSLDNNHSHFVLVEEDPARP-GATSEMRVKLLKHISLQRTGYGAGSFEIPVLCLLVHGEPKILKFLQRMYKGIANSTPWLILAGSGGVADILVTLMNRGCWDTDSVHELL-------LDTFPNAHHSADISNWVK-LIQKILDHGHLLTVHDPEQETSELDTVILKALVKCKSQSQEAQDFLDELKLAVAWNRVDIAKSDIFNGDVEWKACDLE---EVMMDALINDKPDFVRLFVDNGVNLGEFLTYGRLQELYWSV--SEKSLLHNLLLKKYDEKQLLLGAARTPGPPGHYPSEQGKPRFTLFE----VAKVLKDFLHDSCKGFYQKVPTEKPPKGRLFQSQKNLPELE-ELCEHPW--RDLFLWAVLQNRQQMANYFWAMGPEAVAAALAGCKILKEMARL---ESEAESARSMKEA--KYEQFALDVFGECYSNSEDRAYALLVRRTHCWSKSTVLNLATEADAKSFFAHDGVQQALLTKIWWGAMTTDTAISKLVVSFFCPPLIWTNLIKFQFVEL--------DSLDTEKALMLTDD-------DDPRFFLRRWRRFWSAPVTVFLGNVIMYFAFLFLFTYVLLLDFKAPPQGPGV----PEIMLYFWVFTLVLEEIRQSFFTDEEMNIIK-KFKLYVEDNWNKCDMVAILLFVVGVS---CMAAGTYEAGRTVLAIDFMVFTLRLIHIFAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLIAYGVATQALLHPNDPRIDWVFRRALYRPYLHIFGQIPLEEIDARMPKINCTDDSNEIVMGLLPPCPNIYANWLVILLLVIFLLVTNVLLLNLLIAMF-YTFQVVQGNTDIFWKFQRYNLIVEYYSRPALAPPFIIISH 998
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Planmine SMEST
Match: SMESG000005057.1 (SMESG000005057.1) HSP 1 Score: 2105.1 bits (5453), Expect = 0.000e+0 Identity = 1120/1174 (95.40%), Postives = 1133/1174 (96.51%), Query Frame = 3
Query: 93 MEMKN----TKSEITIKNGFEDQIQEFINKKFNTRTCYKYKEKSKDICHCNRHLNHHTNKSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGFLVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFEQFCLNESILEXXXXXXXXXXXXXXETDFFGKVNVKHEVPDVNSSQLETATSYQVRLEYKLEKMERQI 3602
MEM+N +K E GF ++ + FI K F TRTCYKYKEK KD C CNR L HT+KSN PE WSYSNNT L+ C KFG I F+GY ++P EH PKFIRFDC EDCDATCRSVYELMTNSSYWNIP P +IISINGGLK M +ISN HKK FKQGLI+VIKK TWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGFLVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPEFVNLFVENNFDVDNFVNDAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDAVIIIIFIASVVARFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDILFFLSIFVIFVITYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVSSGTVLISFAVFLLMTNVLLINLLIAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFEQFCLNESILESNNNTSDNKDKSNNETDFFGKVNVKHEVPDVNSSQLETATSYQVRLEYKLEKMERQI
Sbjct: 1 MEMENPKHSSKLEFETIKGFGEETKNFIKKNFQTRTCYKYKEKRKDFCSCNRELIEHTDKSNDPENWSYSNNTMLNPCTKFGLINFNGYDDIPREHLPKFIRFDCAEDCDATCRSVYELMTNSSYWNIPAPKLIISINGGLKKMRNISNQHKKNFKQGLINVIKKDQTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGFLVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPEFVNLFVENNFDVDNFVNDAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAPPLKSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDAVIIIIFIASVVARFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDILFFLSIFVIFVITYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVSSGTVLISFAVFLLMTNVLLINLLIAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIFEQENNLMLEHCKPSKSLKLNNFEQFCLNESILESNNNTSDNKDKSNNETDFFGKVNVKHEVPDVNSSQLETATSYQVRLEYKLEKMERQI 1174
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Planmine SMEST
Match: SMESG000005057.1 (SMESG000005057.1) HSP 1 Score: 1331.24 bits (3444), Expect = 0.000e+0 Identity = 685/739 (92.69%), Postives = 698/739 (94.45%), Query Frame = 3
Query: 93 MEMKN----TKSEITIKNGFEDQIQEFINKKFNTRTCYKYKEKSKDICHCNRHLNHHTNKSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGFLVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKG 2297
MEM+N +K E GF ++ + FI K F TRTCYKYKEK KD C CNR L HT+KSN PE WSYSNNT L+ C KFG I F+GY ++P EH PKFIRFDC EDCDATCRSVYELMTNSSYWNIP P +IISINGGLK M +ISN HKK FKQGLI+VIKK TWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGFLVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPEFVNLFVENNFDVDNFVNDAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKG
Sbjct: 1 MEMENPKHSSKLEFETIKGFGEETKNFIKKNFQTRTCYKYKEKRKDFCSCNRELIEHTDKSNDPENWSYSNNTMLNPCTKFGLINFNGYDDIPREHLPKFIRFDCAEDCDATCRSVYELMTNSSYWNIPAPKLIISINGGLKKMRNISNQHKKNFKQGLINVIKKDQTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGFLVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPEFVNLFVENNFDVDNFVNDAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKG 739
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Planmine SMEST
Match: SMESG000005064.1 (SMESG000005064.1) HSP 1 Score: 783.097 bits (2021), Expect = 0.000e+0 Identity = 412/826 (49.88%), Postives = 571/826 (69.13%), Query Frame = 3
Query: 207 KSKDICHCNRHLNHHTNKSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRL--NRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGFLVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQ-----------LFDKPLI----ERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAP---PLK---SEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFD 2615
K + +C C+R + H S E WS+ NNT + C +G I+F+ + P ++ PKFIRFDC E+ ++TC S+Y+L+ + WN+P P +IIS NG L+ ISN HKK KQG I+V+K T V+ SG + GIHKLVSE I EFR HQE+++D+VSLIG++TWG++ NNQ+L +AK N + Y++ +EKGK LD L+D FLFCDDGTEKQYD+EVEF LKFEN++K + D FLVQILFEGGR A+ + Y + D++P+V++KGSG +AN+I+ VM LP+ +KE+I +V EN+ + G E+ E+ N+L E+Y +K+QIVIYDMM+ NM FDKKIL+AMI+G + S+ +TLKLCIRF C IA++ VFSD KY ++ + I++MF+ LK+N+PEF+ LF+ENNF+V+ F+ND IL++LY+ISF+ ++C CAELL +L R ++ + K N + + L+ G ++ KLSGN++ N Y + L D + E F D +EE +L S + Q+LFLWALLSG T++S++ W+I+K+ IGSAL A+ IL+ MA L+L RGDNNL++K ++ SKKYQDL+ I+T+AY K+K KTY LL+R L KWN TCLQIA N +MLEFLNHSACRSY TKVWMG+LSP L WKII+TIPFS +K +I+P+FP K K D D + LL++ + P+K SE+I++ +AM +FY A IVKF I+LLSY+ FL++F Y NLVELKP++++KSIK V AEIYIYIYV TF EEIRQ+++
Sbjct: 2 KKQRLCECSREIGDHKETSKQNEPWSFENNTVSNPCNSYGFIRFTDFEFKPTDYHPKFIRFDCVENAESTCESLYKLLFETDPWNLPIPKLIISFNGSLEKFRFISNQHKKNLKQGFINVMKHDQTLVLSSGFNIGIHKLVSETIYEFRLHQEEMEDKVSLIGINTWGSIANNQKLIFQECNDAKGHQNRLCYYKSPLINEKGKHTLDGLHDNFLFCDDGTEKQYDREVEFRLKFENYLKNKTDAFLVQILFEGGRMAMEHVYTVLNDEIPIVIVKGSGGIANLIASVMELPNSKHKENISALVNENQHLFEKSKG-----EITEYINFLCEIYRKYKRQIVIYDMMNNNMKFDKKILEAMILGYNNSLDKTLKLCIRFKCPKIANRAVFSDSKYQKISRKTIEKMFINCLKENRPEFIELFIENNFEVEKFINDEILRDLYQISFNPDQCQCAELLSELCRSARTTYFTKKNENEIDLDILYIIGKVVQKLSGNVIKNLYEKYKFSTEKNKLVLNDAEIQLNNDETSFNEDFYEENGLL----------SLNAQNLFLWALLSGMTEMSLVFWKINKDQIGSALLASTILRSMASLMLKRGDNNLEKKFSETSKKYQDLSVLILTEAYKKNKMKTYILLIRELKKWNNTTCLQIATNSDMLEFLNHSACRSYITKVWMGELSPILSNWKIILTIPFSFIFIKPLIIPTFPPK-KIMHDESDKMDSSEMKLLEKTEEVQYSYPVKRIESEKISYREAMRVFYGATIVKFYIYLLSYVSFLLIFIYLNLVELKPLEDVKSIKDVLAEIYIYIYVFTFICEEIRQLYE 811
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Planmine SMEST
Match: SMESG000005064.1 (SMESG000005064.1) HSP 1 Score: 782.326 bits (2019), Expect = 0.000e+0 Identity = 413/824 (50.12%), Postives = 569/824 (69.05%), Query Frame = 3
Query: 207 KSKDICHCNRHLNHHTNKSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEEDCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRL--NRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGFLVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVGADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQ-----------LFDKPLI----ERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGKNPKDVPDAKNFHNKHLLDENAKAP---PLK---SEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQV 2609
K + +C C+R + H S E WS+ NNT + C +G I+F+ + P ++ PKFIRFDC E+ ++TC S+Y+L+ + WN+P P +IIS NG L+ ISN HKK KQG I+V+K T V+ SG + GIHKLVSE I EFR HQE+++D+VSLIG++TWG++ NNQ+L +AK N + Y++ +EKGK LD L+D FLFCDDGTEKQYD+EVEF LKFEN++K + D FLVQILFEGGR A+ + Y + D++P+V++KGSG +AN+I+ VM LP+ +KE+I +V EN+ + G E+ E+ N+L E+Y +K+QIVIYDMM+ NM FDKKIL+AMI+G + S+ +TLKLCIRF C IA++ VFSD KY ++ + I++MF+ LK+N+PEF+ LF+ENNF+V+ F+ND IL++LY+ISF+ ++C CAELL +L R ++ + K N + + L+ G ++ KLSGN++ N Y + L D + E F D +EE +L S + Q+LFLWALLSG T++S++ W+I+K+ IGSAL A+ IL+ MA L+L RGDNNL++K ++ SKKYQDL+ I+T+AY K+K KTY LL+R L KWN TCLQIA N +MLEFLNHSACRSY TKVWMG+LSP L WKII+TIPFS +K +I+P+FP K K D D + LL++ + P+K SE+I++ +AM +FY A IVKF I+LLSY+ FL++F Y NLVELKP++++KSIK V AEIYIYIYV TF EEIRQV
Sbjct: 2 KKQRLCECSREIGDHKETSKQNEPWSFENNTVSNPCNSYGFIRFTDFEFKPTDYHPKFIRFDCVENAESTCESLYKLLFETDPWNLPIPKLIISFNGSLEKFRFISNQHKKNLKQGFINVMKHDQTLVLSSGFNIGIHKLVSETIYEFRLHQEEMEDKVSLIGINTWGSIANNQKLIFQECNDAKGHQNRLCYYKSPLINEKGKHTLDGLHDNFLFCDDGTEKQYDREVEFRLKFENYLKNKTDAFLVQILFEGGRMAMEHVYTVLNDEIPIVIVKGSGGIANLIASVMELPNSKHKENISALVNENQHLFEKSKG-----EITEYINFLCEIYRKYKRQIVIYDMMNNNMKFDKKILEAMILGYNNSLDKTLKLCIRFKCPKIANRAVFSDSKYQKISRKTIEKMFINCLKENRPEFIELFIENNFEVEKFINDEILRDLYQISFNPDQCQCAELLSELCRSARTTYFTKKNENEIDLDILYIIGKVVQKLSGNVIKNLYEKYKFSTEKNKLVLNDAEIQLNNDETSFNEDFYEENGLL----------SLNAQNLFLWALLSGMTEMSLVFWKINKDQIGSALLASTILRSMASLMLKRGDNNLEKKFSETSKKYQDLSVLILTEAYKKNKMKTYILLIRELKKWNNTTCLQIATNSDMLEFLNHSACRSYITKVWMGELSPILSNWKIILTIPFSFIFIKPLIIPTFPPK-KIMHDESDKMDSSEMKLLEKTEEVQYSYPVKRIESEKISYREAMRVFYGATIVKFYIYLLSYVSFLLIFIYLNLVELKPLEDVKSIKDVLAEIYIYIYVFTFICEEIRQV 809
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Planmine SMEST
Match: SMESG000004955.1 (SMESG000004955.1) HSP 1 Score: 782.326 bits (2019), Expect = 0.000e+0 Identity = 469/1077 (43.55%), Postives = 693/1077 (64.35%), Query Frame = 3
Query: 255 NKSNSPEEWSYSNNTTLDSCVKFGRIKFSGYPNLPHEHWPKFIRFDCEE--DCDATCRSVYELMTNSSYWNIPDPTMIISINGGLKNMESISNHHKKKFKQGLIDVIKKAPTWVIGSGLSAGIHKLVSEAISEFRFHQEDIKDQVSLIGVSTWGTVKNNQRLNRNLNAKIGTNLVFKYENTSEDEKGKVILDALYDTFLFCDDGTEKQYDKEVEFLLKFENFVKKQADGFLVQILFEGGRRALLNAYKAIKDKVPLVVIKGSGRVANMISEVMGLPSKNYKESIEFIVLENKITLQICTGPEEDAEVEEFTNYLVEMYCNFKKQIVIYDMMDANMSFDKKILQAMIVG-ADKSMKRTLKLCIRFNCSNIADKIVFSDPKYDELGLEVIQEMFLYSLKDNKPXXXXXXXXXXXXXXXXXXXAILKELYEISFDSEKCPCAELLCDLHRDTKSYFKLNKKSNSTEQNRLFDAGDIIAKLSGNLLNNQYSQLFDKPLIERDFLTDSFEEFAMLYESDVDAHKFSWSTQDLFLWALLSGRTDLSMILWRISKNHIGSALFAAIILKKMADLVLIRGDNNLQRKLTDASKKYQDLASSIITQAYNKSKSKTYTLLVRSLAKWNGLTCLQIAINGNMLEFLNHSACRSYTTKVWMGDLSPFLPTWKIIITIPFSLFLMKLMIMPSFPRKGK----NPKDVPDAKNFHNKHL-LDENAKAPPL------KSEEITFIKAMSIFYRAPIVKFSIHLLSYIVFLMVFAYCNLVELKPIQEIKSIKQVWAEIYIYIYVLTFAIEEIRQVFDQEINGAKHKFLSYFYGTWNKFDXXXXXXXXXXXXXRFSIPQNHFMICRCMFSISLSMFLIRSMQFYFVNKSIGPKIIMIRDMLRDXXXXXXXXXXXXXTYGILARSLKYPNSEFNTLLFKDIVYTPFFQTFGELMLENFDVAGPCNGTDCIVSSGTVLISFAVFXXXXXXXXXXXXXAMFGYTFNQIQEDSEKLWCFIRIQLVQEFYGKPIFPPPLNIFYHAFRIISLPCKSRCPKLIF----EQENNLMLEHCKPSKSLKLNNFEQFCLNESILE 3431
N S++P++ + L +C FG+IKF GY ++ P+FIRF + + + YEL+T YWN P P ++ISINGG K M +N KK FKQGL++V++K TW+IG G GIHKLVSEA+++FR ++ ++QV LI +STWG VKNN+ L +GT Y+N++ EKGKV LD YD +LFCDDGTEK+YDKE++F L FE V+ F VQIL+EGG+RA+ + Y++++ +PLVVIK SGR A++I E++ + K ++E + +K Q+ ++ + E L ++Y N+K++I I+D++D N+ DKKIL A+I D+++++TL L +RFNC +IAD VF + L + + F L N+ E + LF+ NNF +D FV + L++LY S S KC C E++ DL FK++ +N +N L II LS N+L FE F + + +A++ S+ ++LFLW+L+SG T++++I W K ++GSAL +IIL KM + +G N++ L S K+Q+LA IIT+AY ++ KT+ +L R L WN LTCLQIAI GN+L+FLN +ACRSYT + WMGDLSPFLPTWKI++TIPFS L+K I+P K + + V D F + + L+ K+P +S++++F +A+ FYRAPIVKF I+LLSYI FL++FAY NLVELKPI+E+K I+ V AE+ +YI++L F +EEI Q+ + E NG +K SY G+WN +D + I IFI S++ RF++ + F+ RC ++++LS+F +R+MQFYF+++SIGPK+IMIR M+ D+ FFLSIF +F+I+YG L+ S++ PNS++N L ++ Y P+FQT+GELML++F + PCN T CIV S T++I F +FLLMTN+LL+NLLIAMFGYTFN+IQ +SEK + FI+IQLV EF+ KP+ PPPLNI Y+ R + + K+IF +++N ++++ ++LK+ FE C+ ++LE
Sbjct: 5 NNSSAPQK------SNLSACKTFGKIKFLGYEDISLNTNPQFIRFFPTDGNNFQELTYNAYELIT--KYWNFPKPQLLISINGGFKRMNFKNNQQKKNFKQGLMEVMRKDTTWIIGGGFHVGIHKLVSEAVNDFRILSDENENQVKLISISTWGVVKNNRSLT------VGT---CAYDNSNTIEKGKVTLDPNYDCYLFCDDGTEKEYDKEIDFRLDFERNVR-DIGAFAVQILYEGGKRAIESIYRSLQKSIPLVVIKESGRAADLICEIL----ETDKMNVEIV---DKYEEQLRLTDDDKIRIIEI---LSDIYSNYKERITIHDLLDQNVHLDKKILDAIISSREDRNLEKTLNLAVRFNCVDIADFKVFQSSRASTLSQKTLGIYFKEMLSKNQHEMLQLFLVNNFSIDEFVQEN-LQDLYMTSLRSIKCRCTEMISDLILREDKSFKIDNINNPG-KNLLKVIYKIICNLSDNIL--------------------KFESFNLRSSNSHNANQNSY--RELFLWSLISGYTEMALIFWENGKENVGSALIGSIILSKMKSYIKSKGFNDMSDTLLKTSIKFQELACDIITKAYKINQEKTHIVLTRPLNLWNNLTCLQIAIGGNLLDFLNLNACRSYTREAWMGDLSPFLPTWKILVTIPFSPLLIKPFIIPYVSNKKSCSNLSHEKVKDKFLFEKEKIELNIRKKSPKSWKSYHSESDQVSFCRALIKFYRAPIVKFVIYLLSYITFLVIFAYLNLVELKPIKEVKVIQNVTAELLVYIFILGFIVEEINQINNTEKNGLIYKLKSYVSGSWNLYDMLTIFIFIISIIMRFTVNGDSFIFVRCFYAVTLSLFSLRTMQFYFISRSIGPKVIMIRKMIVDVFFFLSIFSLFIISYGTLSHSIQNPNSKWNLFLISELFYRPYFQTYGELMLDDFKIPSPCNTTVCIVQSATLIIGFGIFLLMTNILLLNLLIAMFGYTFNKIQGESEKFFSFIQIQLVDEFHNKPLMPPPLNIAYYILRKL-----WQSGKIIFHGDSKRKNTFLIKYLNDDQNLKIRGFEHLCMESAMLE 1024 The following BLAST results are available for this feature:
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member-like 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30003521 ID=SMED30003521|Name=Transient receptor potential cation channel subfamily M member-like 2|organism=Schmidtea mediterranea sexual|type=transcript|length=3752bpback to top protein sequence of SMED30003521-orf-1 >SMED30003521-orf-1 ID=SMED30003521-orf-1|Name=SMED30003521-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1177bp MEMKNTKSEITIKNGFEDQIQEFINKKFNTRTCYKYKEKSKDICHCNRHLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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