TNF receptor associated factor-2

Overview
NameTNF receptor associated factor-2
Smed IDSMED30003487
Length (bp)1181
Neoblast Clusters

Zeng et. al., 2018



 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30003487

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30003487h1SMcG0010955 SmedASXL_009570SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30003487h1SMcG0010955 dd_Smed_v4_28638_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Match: TRAF2 (TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032])

HSP 1 Score: 54.6842 bits (130), Expect = 1.732e-7
Identity = 53/238 (22.27%), Postives = 98/238 (41.18%), Query Frame = 3 
Query:  375 DHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLKSNVLEQ-------MERFQIQMKNQSQRYEQEISILKEKYYR--LENEISQRKTPFN-DNLKQTSSEQQDLETS--------------------------FKWIVCNLSQKRKVN-----HHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            DH++TC      C F   GC    +  E   EH    +  H  ++ S ++  K  + +Q       ++R +  ++ ++  +E  + +L  +  R  +  E   R+   + D ++  SS+ Q LE S                          F W + + ++KR+         + S  FYT +  Y+M LR+ L+      G  +SL F + KG ND    WPF   +++ + ++ N
Sbjct:  204 DHVKTCGKCRVPCRFHAIGCLE-TVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCE-SLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNN 439
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Match: TRAF6 (TNF receptor associated factor 6 [Source:HGNC Symbol;Acc:HGNC:12036])

HSP 1 Score: 53.5286 bits (127), Expect = 4.101e-7
Identity = 71/328 (21.65%), Postives = 136/328 (41.46%), Query Frame = 3 
Query:  240 DCKSRILSFEGNLIKDDITNKQISKLRIKCPLNK--CNYENELI---HVADHIE-TCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLK----SNVLEQMERFQI---QMKNQSQRYEQEISILKEKYYRLENEISQ-RKTPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRKVNHH-----VMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMS--LKFFIH--KGKNDVESIWPFRGNISITM--KNKANLKAGLQ-----ISEYCKIQQPVLGCDSSKVFEFPFVDLRRLK---VLESDSIIIECNITLK 1124
            DC  R +S +         +K+I      CPL    C Y N ++    + +H +  C      C F TFGC    +    ++ HLQ +  +H  ++A  + +L     S  + ++  FQ    Q++ +  R + +I  L  K       +S+ ++T      K    E Q     + W + N     K         + S  FYT K  Y++ +RL L     P+    +  +  F+H  +G+ D    WPF+G I +T+  +++A ++   +       E    Q+P +  +        F+ L  L+    ++ D++++ C ++ +
Sbjct:  181 DCPRRQVSCDNCAASMAFEDKEIHDQ--NCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHE-KMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHL---QLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTR 502
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Match: TRAF6 (TNF receptor associated factor 6 [Source:HGNC Symbol;Acc:HGNC:12036])

HSP 1 Score: 53.5286 bits (127), Expect = 4.101e-7
Identity = 71/328 (21.65%), Postives = 136/328 (41.46%), Query Frame = 3 
Query:  240 DCKSRILSFEGNLIKDDITNKQISKLRIKCPLNK--CNYENELI---HVADHIE-TCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLK----SNVLEQMERFQI---QMKNQSQRYEQEISILKEKYYRLENEISQ-RKTPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRKVNHH-----VMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMS--LKFFIH--KGKNDVESIWPFRGNISITM--KNKANLKAGLQ-----ISEYCKIQQPVLGCDSSKVFEFPFVDLRRLK---VLESDSIIIECNITLK 1124
            DC  R +S +         +K+I      CPL    C Y N ++    + +H +  C      C F TFGC    +    ++ HLQ +  +H  ++A  + +L     S  + ++  FQ    Q++ +  R + +I  L  K       +S+ ++T      K    E Q     + W + N     K         + S  FYT K  Y++ +RL L     P+    +  +  F+H  +G+ D    WPF+G I +T+  +++A ++   +       E    Q+P +  +        F+ L  L+    ++ D++++ C ++ +
Sbjct:  181 DCPRRQVSCDNCAASMAFEDKEIHDQ--NCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHE-KMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHL---QLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTR 502
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: traf1 (TNF receptor-associated factor 1 [Source:ZFIN;Acc:ZDB-GENE-071120-4])

HSP 1 Score: 57.3806 bits (137), Expect = 1.705e-8
Identity = 59/215 (27.44%), Postives = 102/215 (47.44%), Query Frame = 3 
Query:  525 NLKSNVLEQMERFQIQMKNQSQRY---EQEISILKEKYYRLENEISQRKTPFNDNLKQTSSEQQDL--ETSFKWIVCNLSQKRK--VNHHVMSGY---FYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN----LKAGLQISEYCKIQQPV--LGCDSSKVFEFPFVDLRRLK--VLESDSIIIECNI 1115
            N+ S +  ++E+ QI +   ++ +   +Q I  L+     L+  +  RK     +L+Q+ S QQD+  + +F W VC++SQK++   N   +S Y   FYT +  +++ LRL L+      G  +SL F I KG+ D    WPF+  ++  + ++      + A           QPV  +   S     FP   LR  K    + D+I I+C +
Sbjct:  334 NIISALNREVEKTQISVVAMNRDHCNSQQIIQHLEATVAELQQRLV-RKDILISSLQQSISAQQDVSYDGTFYWRVCDVSQKQREAANSQKISQYSPAFYTARYGFKVCLRLYLNGDGAGKGSHISLFFVIMKGEYDPILSWPFKHKVTFFLLDQNQREHVIDAFRPDLSSMSFHQPVSDMNVASGCPLFFPLKKLRSPKHAYCKDDTIYIKCVV 547
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: unm_sa808 (un-named sa808 [Source:ZFIN;Acc:ZDB-GENE-120727-21])

HSP 1 Score: 53.5286 bits (127), Expect = 1.479e-7
Identity = 39/150 (26.00%), Postives = 72/150 (48.00%), Query Frame = 3 
Query:  549 QMERFQIQMK--NQSQRYEQE-ISILKEKYYRLENEISQRK---TPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            ++ERF   M+  N+  R +Q+ I  L  K  +LE ++  +          L++ S+   D    F W + + ++KR+         + S  FYT K  Y+M LR+ L+      G  +SL F + +G +D    WPF   +++ + +++N
Sbjct:   72 EVERFATTMEASNRQHRLDQDKIEALSNKVRQLERQVGVKDLTVAEMEGRLREMSATTFD--GVFIWRISDFTKKRQDAIAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGMSDALLKWPFNQKVTLMLLDQSN 219
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: BX901915.1 (pep chromosome:GRCz11:CHR_ALT_CTG5_1_18:28764891:28768979:-1 gene:ENSDARG00000109857.1 transcript:ENSDART00000191629.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX901915.1)

HSP 1 Score: 52.7582 bits (125), Expect = 2.105e-7
Identity = 45/167 (26.95%), Postives = 75/167 (44.91%), Query Frame = 3 
Query:  522 MNLKSNVLE--------QMERFQIQMK--NQSQRYEQE-ISILKEKYYRLENEISQRK---TPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            + LK N  E        +MER    M+  N+  R +Q+ I IL  K  +LE  +  R          +++ S+   D    F W + + S+KR+         + S  FYT K  Y+M LR+ L+      G  +SL F + +G +D    WPF   +++ + ++ N
Sbjct:   49 LELKVNTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEILNNKVRQLERTVGLRDLSIVEMEAKMREMSAATYD--GVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNN 213
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: AL844899.1 (pep chromosome:GRCz11:CHR_ALT_CTG5_2_4:28756846:28760787:-1 gene:ENSDARG00000111038.1 transcript:ENSDART00000183806.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AL844899.1)

HSP 1 Score: 52.7582 bits (125), Expect = 2.105e-7
Identity = 45/167 (26.95%), Postives = 75/167 (44.91%), Query Frame = 3 
Query:  522 MNLKSNVLE--------QMERFQIQMK--NQSQRYEQE-ISILKEKYYRLENEISQRK---TPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            + LK N  E        +MER    M+  N+  R +Q+ I IL  K  +LE  +  R          +++ S+   D    F W + + S+KR+         + S  FYT K  Y+M LR+ L+      G  +SL F + +G +D    WPF   +++ + ++ N
Sbjct:   49 LELKVNTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEILNNKVRQLERTVGLRDLSIVEMEAKMREMSAATYD--GVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNN 213
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: traf2a (Tnf receptor-associated factor 2a [Source:ZFIN;Acc:ZDB-GENE-071120-2])

HSP 1 Score: 53.5286 bits (127), Expect = 2.514e-7
Identity = 45/167 (26.95%), Postives = 75/167 (44.91%), Query Frame = 3 
Query:  522 MNLKSNVLE--------QMERFQIQMK--NQSQRYEQE-ISILKEKYYRLENEISQRK---TPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            + LK N  E        +MER    M+  N+  R +Q+ I IL  K  +LE  +  R          +++ S+   D    F W + + S+KR+         + S  FYT K  Y+M LR+ L+      G  +SL F + +G +D    WPF   +++ + ++ N
Sbjct:  349 LELKVNTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEILNNKVRQLERTVGLRDLSIVEMEAKMREMSAATYD--GVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNN 513
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415])

HSP 1 Score: 49.2914 bits (116), Expect = 7.008e-6
Identity = 34/138 (24.64%), Postives = 64/138 (46.38%), Query Frame = 3 
Query:  570 QMKNQSQRYEQEISILKEKYYRLENEISQRKTPFND-NLKQTSSEQQDLETSFKWIVCNLSQKRK--VNHH---VMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            ++  Q +  ++++  L  K  +LE  + Q++    +   +   SE    +  F W +    +KR+  +N     + S  FYT K  Y+M LR+ L+         +SL F + KG ND    WPF   +++ + ++ N
Sbjct:  282 ELARQLRAAQEKVEALTTKVRQLERTLGQKELIVAELETRMQESELSTYDGVFIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQNN 419
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835])

HSP 1 Score: 58.5362 bits (140), Expect = 7.822e-9
Identity = 59/241 (24.48%), Postives = 98/241 (40.66%), Query Frame = 3 
Query:  375 DHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLKSN----------------VLEQ---------------MERFQIQMKNQSQRY---EQEISILKEKYYRLENEISQRKTPFNDNLKQTSSEQQDLETS-----FKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            DH+  C      C F T GC S  +  E + +H    +  H  L+ S  +  +++                +LEQ               +ER  +  +  S+++   + +I  L  K  +LE  I  +     D L+Q  SE   LE S     F W + + ++KR+         + S  FYT +  Y+M LR+ L+      G  +SL F + KG ND    WPF   +++ + +  N
Sbjct:  211 DHVRACSKCRVLCRFHTVGC-SEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMAD-LEQKVSE---LEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNN 446
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835])

HSP 1 Score: 58.151 bits (139), Expect = 8.540e-9
Identity = 58/241 (24.07%), Postives = 98/241 (40.66%), Query Frame = 3 
Query:  375 DHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLKSN----------------VLEQ---------------MERFQIQMKNQSQRY---EQEISILKEKYYRLENEISQRKTPFNDNLKQTSSEQQDLETS-----FKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            DH+  C      C F T GC  + +  E + +H    +  H  L+ S  +  +++                +LEQ               +ER  +  +  S+++   + +I  L  K  +LE  I  +     D L+Q  SE   LE S     F W + + ++KR+         + S  FYT +  Y+M LR+ L+      G  +SL F + KG ND    WPF   +++ + +  N
Sbjct:  204 DHVRACSKCRVLCRFHTVGCSEM-VETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMAD-LEQKVSE---LEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNN 439
[Close]
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|P39429|TRAF2_MOUSE (TNF receptor-associated factor 2 OS=Mus musculus OX=10090 GN=Traf2 PE=1 SV=1)

HSP 1 Score: 58.151 bits (139), Expect = 5.974e-8
Identity = 58/241 (24.07%), Postives = 98/241 (40.66%), Query Frame = 3 
Query:  375 DHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLKSN----------------VLEQ---------------MERFQIQMKNQSQRY---EQEISILKEKYYRLENEISQRKTPFNDNLKQTSSEQQDLETS-----FKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            DH+  C      C F T GC  + +  E + +H    +  H  L+ S  +  +++                +LEQ               +ER  +  +  S+++   + +I  L  K  +LE  I  +     D L+Q  SE   LE S     F W + + ++KR+         + S  FYT +  Y+M LR+ L+      G  +SL F + KG ND    WPF   +++ + +  N
Sbjct:  204 DHVRACSKCRVLCRFHTVGCSEM-VETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMAD-LEQKVSE---LEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNN 439
[Close]
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|Q12933|TRAF2_HUMAN (TNF receptor-associated factor 2 OS=Homo sapiens OX=9606 GN=TRAF2 PE=1 SV=2)

HSP 1 Score: 54.6842 bits (130), Expect = 8.319e-7
Identity = 53/238 (22.27%), Postives = 98/238 (41.18%), Query Frame = 3 
Query:  375 DHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLKSNVLEQ-------MERFQIQMKNQSQRYEQEISILKEKYYR--LENEISQRKTPFN-DNLKQTSSEQQDLETS--------------------------FKWIVCNLSQKRKVN-----HHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            DH++TC      C F   GC    +  E   EH    +  H  ++ S ++  K  + +Q       ++R +  ++ ++  +E  + +L  +  R  +  E   R+   + D ++  SS+ Q LE S                          F W + + ++KR+         + S  FYT +  Y+M LR+ L+      G  +SL F + KG ND    WPF   +++ + ++ N
Sbjct:  204 DHVKTCGKCRVPCRFHAIGCLE-TVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCE-SLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNN 439
[Close]
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|B6CJY5|TRAF6_MACMU (TNF receptor-associated factor 6 OS=Macaca mulatta OX=9544 GN=TRAF6 PE=2 SV=1)

HSP 1 Score: 54.299 bits (129), Expect = 1.082e-6
Identity = 72/338 (21.30%), Postives = 134/338 (39.64%), Query Frame = 3 
Query:  216 KFCPGSATDCK--SRILSFEGNLIKDDITNKQISKLRIKCPLNK--CNYENELI---HVADHIE-TCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLK----SNVLEQMERFQI---QMKNQSQRYEQEISILKEKYYRLENEISQ-RKTPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRKVNHH-----VMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMS--LKFFIH--KGKNDVESIWPFRGNISITMKNKANLKAGLQISE-------YCKIQQPVLGCDSSKVFEFPFVDLRRLK---VLESDSIIIECNITLK 1124
            K CP     C   + +++FE   I D             CPL    C Y N ++    + +H +  C      C F TFGC    +    ++ HLQ +  +H  ++A  + +L     S  + ++  FQ    Q++ +  R + +I  L  K       +S+ ++T      K    E Q     + W + N     K         + S  FYT K  Y++ +RL L     P+    +  +  F+H  +G+ D    WPF+G I +T+ +++         E           Q+P +  +        F+ L  L+    ++ D++++ C ++ +
Sbjct:  180 KDCPRRQVSCDNCAALVAFEDKEIHDQ-----------NCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHE-KMQRNHLARHLQENTQSHMRMLAQAVHSLSLIPDSGYVSEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSTYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHL---QLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPDLLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTR 502
[Close]
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|B6CJY4|TRAF6_CERAT (TNF receptor-associated factor 6 OS=Cercocebus atys OX=9531 GN=TRAF6 PE=2 SV=1)

HSP 1 Score: 54.299 bits (129), Expect = 1.131e-6
Identity = 72/338 (21.30%), Postives = 134/338 (39.64%), Query Frame = 3 
Query:  216 KFCPGSATDCK--SRILSFEGNLIKDDITNKQISKLRIKCPLNK--CNYENELI---HVADHIE-TCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLK----SNVLEQMERFQI---QMKNQSQRYEQEISILKEKYYRLENEISQ-RKTPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRKVNHH-----VMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMS--LKFFIH--KGKNDVESIWPFRGNISITMKNKANLKAGLQISE-------YCKIQQPVLGCDSSKVFEFPFVDLRRLK---VLESDSIIIECNITLK 1124
            K CP     C   + +++FE   I D             CPL    C Y N ++    + +H +  C      C F TFGC    +    ++ HLQ +  +H  ++A  + +L     S  + ++  FQ    Q++ +  R + +I  L  K       +S+ ++T      K    E Q     + W + N     K         + S  FYT K  Y++ +RL L     P+    +  +  F+H  +G+ D    WPF+G I +T+ +++         E           Q+P +  +        F+ L  L+    ++ D++++ C ++ +
Sbjct:  180 KDCPRRQVSCDNCAALVAFEDKEIHDQ-----------NCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHE-KMQRNHLARHLQENTQSHMRMLAQAVHSLSLIPDSGYVSEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSTYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHL---QLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPDLLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTR 502
[Close]
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|Q9Y4K3|TRAF6_HUMAN (TNF receptor-associated factor 6 OS=Homo sapiens OX=9606 GN=TRAF6 PE=1 SV=1)

HSP 1 Score: 53.5286 bits (127), Expect = 1.970e-6
Identity = 71/328 (21.65%), Postives = 136/328 (41.46%), Query Frame = 3 
Query:  240 DCKSRILSFEGNLIKDDITNKQISKLRIKCPLNK--CNYENELI---HVADHIE-TCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLK----SNVLEQMERFQI---QMKNQSQRYEQEISILKEKYYRLENEISQ-RKTPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRKVNHH-----VMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMS--LKFFIH--KGKNDVESIWPFRGNISITM--KNKANLKAGLQ-----ISEYCKIQQPVLGCDSSKVFEFPFVDLRRLK---VLESDSIIIECNITLK 1124
            DC  R +S +         +K+I      CPL    C Y N ++    + +H +  C      C F TFGC    +    ++ HLQ +  +H  ++A  + +L     S  + ++  FQ    Q++ +  R + +I  L  K       +S+ ++T      K    E Q     + W + N     K         + S  FYT K  Y++ +RL L     P+    +  +  F+H  +G+ D    WPF+G I +T+  +++A ++   +       E    Q+P +  +        F+ L  L+    ++ D++++ C ++ +
Sbjct:  181 DCPRRQVSCDNCAASMAFEDKEIHDQ--NCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHE-KMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHL---QLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTR 502
[Close]
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: T1E101 (TRAF-6 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 4.845e-16
Identity = 62/212 (29.25%), Postives = 117/212 (55.19%), Query Frame = 3 
Query:   39 ATNFDKIWEVIGRFDFDK-DLKLSVHVVCTICNKLLTNTXXXXXXXXXXXXXITDYIGK-EKFCPGSATDCKSRILSFEGNLIKDDITNKQISKLRIKCPLNKCNYENELIHVADHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLKSNVLEQMERFQIQMKNQSQRYEQEISILKEKYYRLENEISQRKTP 668
             +  D + E++ +++  + D  ++  ++C +CNKL+ +  +  CGC YC  CI  Y+ +   +CPG  T+CK   L+ EG++ ++   + +IS++ +KCP  +CNY +EL+ + +H++ C   S  CP +T GC    L  + +++HL   +  H  L+ S+   LKS         +I   N++ +  ++IS LKE   R++  ++  KT 
Sbjct:    3 PSKLDNVQELLSKYNVKRVDESVNNDLLCILCNKLMRDACESACGCHYCYTCIRIYLSQNHNYCPGDKTECKEDYLNLEGDVFRNIRLSTRISRIVVKCPNIRCNYTSELLRLKEHLDKCTPESVECPCVTIGCEEEPLLKDEMAKHLTDQVLRHTQLIMSFCNELKS---------EINHNNETTK--EDISHLKE-VLRVQKALNDEKTA 202
[Close]
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: I1ZID8 (TNF receptor associated factor-2 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 83.9593 bits (206), Expect = 4.976e-15
Identity = 56/201 (27.86%), Postives = 110/201 (54.73%), Query Frame = 3 
Query:   51 DKIWEVIGRFDFDKDLKLSVHVVCTICNKLLTNTXXXXXXXXXXXXXITDYIGKEK-FCPGSATDCKSRILSFEGNLIKDDITNKQISKLRIKCPLNKCNYENELIHVADHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLKSNVLEQMERFQIQMKNQSQRYEQEISILKEKYYRLENEI 650
            +KI  ++  ++F+ +  +  ++ C +C  LL N  +  CGC++C KCI +Y+ +   +CPG  ++CK   L+   N+  D   N++I+K+R+KCP   C    EL+ + +H+  C   S +CPF   GC    +  + ++ HLQ+    H+ L+   + N++++       F +  K    R  ++I+++K  +++ +NEI
Sbjct:    4 EKINRLLITYNFEVEGGVPDNLKCDLCKNLLVNACQSRCGCRFCSKCIMEYVSRGNLYCPGGTSECKEENLTICSNIHTDYRVNRKIAKMRVKCPEETCKVYCELVDIEEHLRLCTMKSQNCPFFVLGCNQPKMVIQDLTNHLQNGTFQHSKLIIDIISNMRNDF------FGLTTKEVELR--EDINLIK-NHFQSQNEI 195
[Close]
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: T1DF65 (TRAF-2 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.291e-13
Identity = 71/244 (29.10%), Postives = 112/244 (45.90%), Query Frame = 3 
Query:  285 DDITNKQISKLRIKCPLNKCNYENELIHVADHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLKSNVLEQMERFQIQMKNQSQRYEQEISILKEKYYRLENEISQRKTPFND------------NLKQTS-SEQQDLETSFKWIVCNLSQK-----RKVNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKA 962
            +++ +   SK R  CP  KC+ E+ L+++ DH+ TC+     C     GCR V L  E + EH     N H  L+   +  L+    ++ +   + +  Q++R   EI  LKEK   L  EI   KT                NL + S SE ++    + W V N+ +K     + VN  ++S  FY+    Y M L++  +   +  G  +S+ F + KGK D +  WPF   ISI + N A
Sbjct:  173 NELIDNVCSKWRDICPF-KCS-EDTLVNIKDHLLTCERRPVECSLNEMGCRKV-LPREEMREHFNLEANYHTVLLMDALFLLR----KEHQDLSVSVSVQNERNSAEIKELKEKLSSLLTEIEDLKTKLKQFQSMYEKLENERNLAKCSLSETKERYGEYTWKVENIMEKVNDAKKGVNTQILSESFYSSNPGYRMCLKIYPNGDGSAFGNYLSVYFVLMKGKYDDQIQWPFNSIISIRLVNIA 409
[Close]
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: A0A0F7GWW3 (TNF receptor associated factor 4 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 2.321e-8
Identity = 43/132 (32.58%), Postives = 70/132 (53.03%), Query Frame = 3 
Query:  273 NLIKDDITNKQISKLRIKCPLNKCNYENELIHVADHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLKSNVLEQMERFQIQMKNQSQRYEQEISILKEKYYRLENEIS--QRK 662
            N+  D   N +I+KL++KC    C+Y +EL  + DH  TCK  S  CP+   GC   N++ + +++HLQS I  H  L+  +++N  +N +E ++     +   ++    EI+ LK    R   EI   QRK
Sbjct:   15 NICVDYPMNMKIAKLQVKCKEKSCDYVDELRKMEDHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNF-NNEMEMLKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRK 145
[Close]
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: H0YW37 (TNF receptor-associated factor OS=Taeniopygia guttata OX=59729 GN=TRAF2 PE=3 SV=1)

HSP 1 Score: 66.2402 bits (160), Expect = 5.465e-8
Identity = 58/235 (24.68%), Postives = 102/235 (43.40%), Query Frame = 3 
Query:  375 DHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLKSNV-----------LEQMERFQIQMKNQS---QRYEQEISILKEKYYR-----------LENEISQ--RKTPFND-NLKQTSSEQQDLETS-----FKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            DH++TC      C F   GC  V + +E + EH +  +  H  ++ S +++LK+              E +ER  +  +N      R  + +S+  E Y R           L N++ Q  R     D  + +   + +++E S     F W +   ++KR+      +  + S  FYT K  Y+M LR+ L+      G  +SL F + KG ND    WPF   +++ + ++ N
Sbjct:  204 DHVKTCGRSKVPCRFEAVGCAEV-VENEKLPEHERKCLAEHLYMLMSSVLSLKTGAGDLKPLPLLGRCEALERKTVTFENIVCVLNREVERVSLTAEAYSRQHRLDQEKIETLSNKVRQLERSIGLKDLAMAEMEEKIRNMEASTYDGVFIWKITEFARKRQEAITGRSPAIFSPAFYTSKYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNN 437
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375])

HSP 1 Score: 53.5286 bits (127), Expect = 2.300e-7
Identity = 41/150 (27.33%), Postives = 70/150 (46.67%), Query Frame = 3 
Query:  549 QMERFQIQMK--NQSQRYEQE-ISILKEKYYRLENEISQRK---TPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            +MER    M+  N+  R +Q+ I IL  K  +LE  +  R          +++ S+   D    F W + + S+KR+         + S  FYT K  Y+M LR+ L+      G  +SL F + +G +D    WPF   +++ + ++ N
Sbjct:  363 EMERSATTMEAYNRQHRLDQDKIEILNNKVRQLERTVGLRDLSIVEMEGKMREMSAATYD--GVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNN 510
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375])

HSP 1 Score: 53.1434 bits (126), Expect = 2.611e-7
Identity = 41/150 (27.33%), Postives = 70/150 (46.67%), Query Frame = 3 
Query:  549 QMERFQIQMK--NQSQRYEQE-ISILKEKYYRLENEISQRK---TPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            +MER    M+  N+  R +Q+ I IL  K  +LE  +  R          +++ S+   D    F W + + S+KR+         + S  FYT K  Y+M LR+ L+      G  +SL F + +G +D    WPF   +++ + ++ N
Sbjct:  250 EMERSATTMEAYNRQHRLDQDKIEILNNKVRQLERTVGLRDLSIVEMEGKMREMSAATYD--GVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNN 397
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252])

HSP 1 Score: 49.6766 bits (117), Expect = 3.801e-6
Identity = 43/164 (26.22%), Postives = 77/164 (46.95%), Query Frame = 3 
Query:  678 NLKQTSSEQQDL--ETSFKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN-------LKAGLQISEYCKIQQPV--LGCDSSKVFEFPFVDLRRLK--VLESDSIIIECNI 1115
            +L+Q+ S QQD+  + +F W +C++SQK K           S  FYT +  +++ +RL +       G  +SL F I KG  D    WPF+  ++  + ++          +  L+ + +   Q+PV  +   S     FP   LR  K   ++ D++ I+C +
Sbjct:  354 SLQQSISAQQDVSYDGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQNQREHVVDAFRPDLRSASF---QRPVSEMNVASGCPLFFPLSKLRSPKHAYVKDDTLFIKCVV 514
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:103028261])

HSP 1 Score: 49.6766 bits (117), Expect = 3.916e-6
Identity = 62/267 (23.22%), Postives = 102/267 (38.20%), Query Frame = 3 
Query:  372 ADHIETCKCLSNHCPFLTFGCRSVNLADEGIS-EHLQSHINNHNTLMASWMMNL---------------------------------------------KSNVLE--------QMERFQIQMK---NQSQRYEQEISILKEKYYRLENEISQRKTPFNDNLKQTSSEQQDLETSF-------KWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            A+H ++C    + C F   GCR+V   D G   EH QS I  H  LM + +  +                                             K   LE        ++ER  ++++    Q Q  +++I  L  K  +LE  ++ R      +L+   SEQ   E  F        W + + S++R+         + S  FY+ K  Y+M LRL L+      G  +SL F + +GK D    WPF   +++ + ++ N
Sbjct:  211 AEHSKSCAKSKSACQFSEIGCRAV--VDNGKQHEHEQSSIIEHLRLMLAVLSTVRVRSDGPGEWQEDSGLGLYRGPEDAAPPGAHAAAHNAAGGPGVQQKMTALENIVCVLNREVERTVLRLEALTRQQQLDQEKIENLSNKVRQLERTLTMR------DLQLAESEQALRELQFCTYDGVFVWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLLDQNN 469
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252])

HSP 1 Score: 49.2914 bits (116), Expect = 4.668e-6
Identity = 43/164 (26.22%), Postives = 77/164 (46.95%), Query Frame = 3 
Query:  678 NLKQTSSEQQDL--ETSFKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN-------LKAGLQISEYCKIQQPV--LGCDSSKVFEFPFVDLRRLK--VLESDSIIIECNI 1115
            +L+Q+ S QQD+  + +F W +C++SQK K           S  FYT +  +++ +RL +       G  +SL F I KG  D    WPF+  ++  + ++          +  L+ + +   Q+PV  +   S     FP   LR  K   ++ D++ I+C +
Sbjct:  377 SLQQSISAQQDVSYDGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQNQREHVVDAFRPDLRSASF---QRPVSEMNVASGCPLFFPLSKLRSPKHAYVKDDTLFIKCVV 537
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Match: EDO48773 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI91])

HSP 1 Score: 48.1358 bits (113), Expect = 3.637e-6
Identity = 60/258 (23.26%), Postives = 105/258 (40.70%), Query Frame = 3 
Query:  234 ATDCKSRILSFEGNLIKDDITNKQISKLRIKCPLNKCNYENELIHVADHIETCKCLSNHCPFLTFGCRSVNL--ADEGISEHLQSHINNHNTLMASWMMNLKSNVLEQMERFQIQMKNQSQRYEQEISILKEKYYRLENEISQRKTPFNDNLKQTSSEQQDLET-----SFKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESI--WPFRGNISITMKNKAN 965
            A  C +R  S   +  K  +T  +I +    CP    N  NE   V    E  K  +  CP  +  C    +  + E  S   Q H  +   L    +    +     M+R    + ++   Y Q ++ L+ K   ++    +R       L +  + + +LE      +F W + N  Q R+     +   + S  FYT    Y+M LR+ L+      G  +SL  FIH  + D + I  WPF G I++++ ++++
Sbjct:  171 AEACPNR--SVPCDHCKMKVTISKIEEHLKGCPCMDTNCPNECGAVMQRKEVDKHCAEACPNRSVPCDHCKMKSSKEQASHGPQEHTPHEAELRREALFQSAN-----MQREVDMLGSRGDEYRQFLAYLERKVEDVKTSSDRRIAELTHKLMRLETREIELEGRVCNGTFIWKLDNFRQCREGSIAGLTAAIHSPPFYTSMYGYKMCLRMNLNGVDGGLGEHVSL--FIHMMQGDWDGILEWPFIGRITLSILDQSD 419
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Match: EDO48394 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJK8])

HSP 1 Score: 47.3654 bits (111), Expect = 7.260e-6
Identity = 66/332 (19.88%), Postives = 120/332 (36.14%), Query Frame = 3 
Query:  243 CKSRILSFEGNLIKDDITNKQISKLRIKCPLNKCNYENELIHVADHIETCKCLSNHC---------------------PFLTFGCRSVNLA------DEGISEHLQSHINNHNTLMASWMMNLK---SNVLEQMERFQIQMKNQSQRYEQEISILKEKYYRL------------------ENEISQRKTPFNDNLKQ--------------------TSSEQQDLETSFKWIVCNLSQKRK------VNHHVMSG------------------YFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKA 962
            C +    ++G L +     K  S   +KC L  CN +   I +  H  TC     HC                     P     CR   +       +    EH +S +  H  +    + + K   S++ +++++ + +++ +S  + +E++ ++EK+                      N I + K    D LK+                    T+ + Q  + +F W +CN   K K       N  V  G                   FYT +  Y+MRL+   + + +  G  +SL   I KG+ D    WPFR  I++++ N++
Sbjct:   95 CTNNPCRWKGELRQKQKHLKICSHKAVKCILEGCNVKVPRILMEKHTNTCGWRLLHCKPCNLSYPKKDEETVQHKDDCPLAFLPCRFSEIGCTFKGRESARDEHCESAVQTHLHIACETIRDNKEQISDLHKELDKVRQELQTKSCDHMKEVNAIREKHDEAIRDNKGQIEALSKEHGIASNTIHENKEQL-DTLKKELGIASETIRKNRDQIAKLSTACKTQYTDGTFVWRICNYKDKYKKAVAFATNQEVKGGNSDSDDDISMAGDIMVSLPFYTSRYGYKMRLKAYPNGYGDGKGTHLSLSIRIMKGEYDAILEWPFRRKITLSLINQS 425
[Close]
BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Match: ENSORLT00000020861.2 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101167626])

HSP 1 Score: 50.8322 bits (120), Expect = 1.810e-6
Identity = 38/142 (26.76%), Postives = 66/142 (46.48%), Query Frame = 3 
Query:  567 IQMKNQSQRYEQE-ISILKEKYYRLENEISQRK---TPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKAN 965
            ++  N+  R +Q+ I IL  K  +LE  +S R          +K  S+   D    F W + + ++KR+         + S  FYT K  Y+M LR+ L+      G  +SL F + +G +D    WPF   +++ + ++ N
Sbjct:  368 MEAYNRQHRLDQDKIEILSNKVRQLERTVSLRDLSIVEMEGKMKDMSAATYD--GIFIWKISDFTKKRQDAMAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNN 507
[Close]
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000057298.1 (SMESG000057298.1)

HSP 1 Score: 711.835 bits (1836), Expect = 0.000e+0
Identity = 360/367 (98.09%), Postives = 362/367 (98.64%), Query Frame = 3 
Query:   24 MANSQATNFDKIWEVIGRFDFDKDLKLSVHVVCTICNKLLTNTXXXXXXXXXXXXXITDYIGKEKFCPGSATDCKSRILSFEGNLIKDDITNKQISKLRIKCPLNKCNYENELIHVADHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLKSNVLEQMERFQIQMKNQSQRYEQEISILKEKYYRLENEISQRKTPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRKVNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKANLKAGLQISEYCKIQQPVLGCDSSKVFEFPFVDLRRLKVLESDSIIIECNITLK 1124
            MANSQATNFDKIWEVIGRFDFDKDLKLSVHVVCTICNKLL NTYKGPCGCKYCKKCIT+YIGKEKFCPGSATDCKSRILSFE NLIKDDITNKQISKLRIKCPLNKCNYENELIHVADHIETCKCLSNHCPFLTFGCRSVN  DEGISEHLQSHINNHNTLMASWMMNLKSNVLEQMERFQIQMKNQSQRYEQEISILKEKYYRLENEISQRKTPFNDNLKQT SEQQDLETSFKWIVCNLSQKRKVNHHVMSGYFYTYKKDYEMRLRLCLSDHH+PSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKANLKAGLQISEYCKIQQPVLGCDSSKVFEFPFVDLRRLKVLESDSIIIECNITLK
Sbjct:    1 MANSQATNFDKIWEVIGRFDFDKDLKLSVHVVCTICNKLLINTYKGPCGCKYCKKCITNYIGKEKFCPGSATDCKSRILSFESNLIKDDITNKQISKLRIKCPLNKCNYENELIHVADHIETCKCLSNHCPFLTFGCRSVNSTDEGISEHLQSHINNHNTLMASWMMNLKSNVLEQMERFQIQMKNQSQRYEQEISILKEKYYRLENEISQRKTPFNDNLKQTGSEQQDLETSFKWIVCNLSQKRKVNHHVMSGYFYTYKKDYEMRLRLCLSDHHHPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKANLKAGLQISEYCKIQQPVLGCDSSKVFEFPFVDLRRLKVLESDSIIIECNITLK 367
[Close]
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000009561.1 (SMESG000009561.1)

HSP 1 Score: 134.42 bits (337), Expect = 4.423e-35
Identity = 117/434 (26.96%), Postives = 211/434 (48.62%), Query Frame = 3 
Query:   54 KIWEVIGRFDFDKDLKLSVHVVCTICNKLLTNTXXXXXXXXXXXXXITDYIGKE-KFCPGSATDCKSRILSFEGNLIKDDITNKQISKLRIKCPLNKCNYENELIHVADHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHN-------TLMASWMMNLKS-------NVLEQ-------------------------MERFQIQ----------MKNQSQRYEQEI---------------SILKEKYYR-----LENEISQRK--TPFN-------DNLKQTSSEQQDLETSFKWIVCNLSQKRKVNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKN-DVESIWPFRGNISITMKNKANLKAGLQISEYCKIQQPVLGCDSSKVFEFPFVDLRRLKVLESDSIIIECNI 1115
            K+W ++ ++ F+ D K+ ++V C+ICN LL N Y+GPC C YCK CI  Y+G + K CPG + +C+   +S   ++IKD   + ++S+L ++CP N C ++ +L+++ DH+ TC      CPF   GC+++   +  I +HL  +I  H+       T++ +  +N +        NVL+Q                         +E+ QI+          ++N  + Y Q+I                ++K K+++      E+    RK  + FN       D+L    SE   +  S  WIV  +S+K K   ++ S  F++  + ++M L L    +   +G  +S+ F+I   K  +   ++PF+ NI + + NK    + L IS  C+ +   L   +S++F F   +L +  V  SD+++IEC++
Sbjct:    6 KMWTILDKYPFEIDPKVLIYVKCSICNGLLRNAYQGPCCCNYCKTCIEIYLGDDRKHCPGDSIECRQEQISMRNHIIKDRGADYRVSQLDVRCPWNSCRFQGKLLNMDDHLRTCNKSPIECPFTELGCQTILTENINIKDHLLDNICQHSKLISNWITILKNETLNCEGSAIKQLRNVLKQNVIVLVDRKISQVRCNLRNAEIEPLLEKIQIESIKREKLKDEIRNLEKDYGQKILFHKNELEKQRILIRKLMKNKHHKNLALSKESGNHDRKCISKFNSIQQHGRDDLCGVKSE---MAASLSWIVTEISRKTKYKINLKSENFHSNDRQFQMNLLLYPGGYERYTGTHLSIAFYIRPWKAVNPSKLFPFKCNILMRISNKFQTNSQLDISNNCQFKSQNL---NSEIFHFSLDELEQTAVTYSDTVVIECSV 433
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BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000024592.1 (SMESG000024592.1)

HSP 1 Score: 132.88 bits (333), Expect = 1.160e-34
Identity = 118/430 (27.44%), Postives = 202/430 (46.98%), Query Frame = 3 
Query:   33 SQATNFDKIWEVIGRFDFDKDLKLSVHVVCTICNKLLTNTXXXXXXXXXXXXXITDYIGKE-KFCPGSATDCKSRILSFEGNLIKDDITNKQISKLRIKCPLNKCNYENELIHVADHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLKSNV------LEQMERFQIQMKNQSQRYEQEISILKEKYYRLENEISQR---------------KTPFNDNLKQT------SSEQ--------------------QDLETSFKWIVCNLSQKRKVNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKANLKAGLQISEYCKIQQPVLGCDSSK------------------VFEFPFVDLRRLKVLESDSIIIECNITLK 1124
            S +   D I+E+I + DF+    +S  + CT+C K+L N Y+ PCGC +C+KCI ++I  E K CPG + +CK + L+   NL  D   N ++ KL +KCP   C Y+ +L ++ +H+  C   S  CP+   GC  V +A + + +H+QS I +HN+++      +K ++       E  E     +KN  +  E +I  LK +   L N+I+++                  F+  LKQ       S+E+                      +  S  W +  +++ RK    V S YFY     Y+M+L L  +   N +G  +S+  +I+      +  WPF+G ++I + NK +  A ++ S+YC I     G D ++                   F+F + +L    VL+++ I +ECN+ +K
Sbjct:    2 SHSEKLDSIFELIMKNDFEAIENISEDLKCTLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLT---NLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLLYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQSKYCIIDNFEEGLDDAEGSLFMDDSIDSCDYQWDNQFDFLYNELSASGVLDNNIITVECNVEIK 428
[Close]
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000009561.1 (SMESG000009561.1)

HSP 1 Score: 132.88 bits (333), Expect = 1.578e-34
Identity = 116/433 (26.79%), Postives = 210/433 (48.50%), Query Frame = 3 
Query:   57 IWEVIGRFDFDKDLKLSVHVVCTICNKLLTNTXXXXXXXXXXXXXITDYIGKE-KFCPGSATDCKSRILSFEGNLIKDDITNKQISKLRIKCPLNKCNYENELIHVADHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHN-------TLMASWMMNLKS-------NVLEQ-------------------------MERFQIQ----------MKNQSQRYEQEI---------------SILKEKYYR-----LENEISQRK--TPFN-------DNLKQTSSEQQDLETSFKWIVCNLSQKRKVNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKN-DVESIWPFRGNISITMKNKANLKAGLQISEYCKIQQPVLGCDSSKVFEFPFVDLRRLKVLESDSIIIECNI 1115
            +W ++ ++ F+ D K+ ++V C+ICN LL N Y+GPC C YCK CI  Y+G + K CPG + +C+   +S   ++IKD   + ++S+L ++CP N C ++ +L+++ DH+ TC      CPF   GC+++   +  I +HL  +I  H+       T++ +  +N +        NVL+Q                         +E+ QI+          ++N  + Y Q+I                ++K K+++      E+    RK  + FN       D+L    SE   +  S  WIV  +S+K K   ++ S  F++  + ++M L L    +   +G  +S+ F+I   K  +   ++PF+ NI + + NK    + L IS  C+ +   L   +S++F F   +L +  V  SD+++IEC++
Sbjct:    1 MWTILDKYPFEIDPKVLIYVKCSICNGLLRNAYQGPCCCNYCKTCIEIYLGDDRKHCPGDSIECRQEQISMRNHIIKDRGADYRVSQLDVRCPWNSCRFQGKLLNMDDHLRTCNKSPIECPFTELGCQTILTENINIKDHLLDNICQHSKLISNWITILKNETLNCEGSAIKQLRNVLKQNVIVLVDRKISQVRCNLRNAEIEPLLEKIQIESIKREKLKDEIRNLEKDYGQKILFHKNELEKQRILIRKLMKNKHHKNLALSKESGNHDRKCISKFNSIQQHGRDDLCGVKSE---MAASLSWIVTEISRKTKYKINLKSENFHSNDRQFQMNLLLYPGGYERYTGTHLSIAFYIRPWKAVNPSKLFPFKCNILMRISNKFQTNSQLDISNNCQFKSQNL---NSEIFHFSLDELEQTAVTYSDTVVIECSV 427
[Close]
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000014923.1 (SMESG000014923.1)

HSP 1 Score: 126.331 bits (316), Expect = 3.573e-32
Identity = 114/438 (26.03%), Postives = 204/438 (46.58%), Query Frame = 3 
Query:   48 FDKIWEVIGRFDFDKDLKLSVHVVCTICNKLLTNTXXXXXXXXXXXXXITDYIGK-EKFCPGSATDCKSRILSFEGNLIKDDITNKQISKLRIKCPLNKCNYENELIHVADHIETCKCLSNHCPFLTFGCRSVNLADEGISEHLQSHINNHNTLMASWMMNLKSNVLEQMERFQ--IQMKNQSQR-------YEQEISILKEKYYRLENE-------ISQRKTPFND-----NLKQTSSEQQDLE----------------------------------------TSFKWIVCNLSQKRK-----VNHHVMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWPFRGNISITMKNKANLKAGLQISEYCKIQQPVLG----------CDSSKVFEFPFVDLRRL----KVLESDSIIIECNIT 1118
            ++ IW ++  +  +   ++S  ++C IC  LL N   GPCGC+YC +CI  Y+G+ EKFCP +  +CK  +L+ + N++ D+  N +IS++ +KCP   C + +EL  + DHI  C      CP+   GC    +A E I++HL      H   + + + NLK+ +    E F+   ++K++SQ+        + +IS  K K+ +  +E       + Q +    D     ++KQ ++E Q +E                                         S +W + N ++KRK     +   + S  FY++K  Y+M L+L         G ++S+ FFI +G+NDV   WP +  ++I + N+   ++G   + Y     PVL            D +  + + F+ L  L    K+L++D I+++C + 
Sbjct:    6 YENIWRILSEYRVNSMTEISSDLICVICKNLLKNACNGPCGCRYCFECIQSYLGQVEKFCPQNFDECKEELLNIDRNILLDNAANSRISRIIVKCPEPSCEFHDELRKIGDHINACDKKIVKCPYFDIGCSEGKVASERINDHLIVDNYTHAKTLVNCIQNLKNEMALMKECFEELKKIKDESQKKQSLLYDLQDKISEFKRKFIQKSDENIHLKLKLQQTEHKLEDLRHQLDMKQNATENQMIELLLENEKLKYKSDENQRFSEILHGKLESLERETLSMKQHFGSIQWKIDNFTKKRKEAQSGIIADIYSEPFYSHKNGYKMCLQLHPDGFKAGKGTNLSVFFFIMRGENDVILQWPMKLEVTIGIINQ---ESGDIHTSYKFNYDPVLDKYRHLFDKPKTDINVGYGYDFIKLDELIKNNKLLKNDRIVLKCVVA 440
The following BLAST results are available for this feature:
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
TRAF21.732e-722.27TNF receptor associated factor 2 [Source:HGNC Symb... [more]
TRAF64.101e-721.65TNF receptor associated factor 6 [Source:HGNC Symb... [more]
TRAF64.101e-721.65TNF receptor associated factor 6 [Source:HGNC Symb... [more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TNF receptor associated factor-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf11.705e-827.44TNF receptor-associated factor 1 [Source:ZFIN;Acc:... [more]
unm_sa8081.479e-726.00un-named sa808 [Source:ZFIN;Acc:ZDB-GENE-120727-21... [more]
BX901915.12.105e-726.95pep chromosome:GRCz11:CHR_ALT_CTG5_1_18:28764891:2... [more]
AL844899.12.105e-726.95pep chromosome:GRCz11:CHR_ALT_CTG5_2_4:28756846:28... [more]
traf2a2.514e-726.95Tnf receptor-associated factor 2a [Source:ZFIN;Acc... [more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
TRAF27.008e-624.64TNF receptor associated factor 2 [Source:NCBI gene... [more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Traf27.822e-924.48TNF receptor-associated factor 2 [Source:MGI Symbo... [more]
Traf28.540e-924.07TNF receptor-associated factor 2 [Source:MGI Symbo... [more]
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BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P39429|TRAF2_MOUSE5.974e-824.07TNF receptor-associated factor 2 OS=Mus musculus O... [more]
sp|Q12933|TRAF2_HUMAN8.319e-722.27TNF receptor-associated factor 2 OS=Homo sapiens O... [more]
sp|B6CJY5|TRAF6_MACMU1.082e-621.30TNF receptor-associated factor 6 OS=Macaca mulatta... [more]
sp|B6CJY4|TRAF6_CERAT1.131e-621.30TNF receptor-associated factor 6 OS=Cercocebus aty... [more]
sp|Q9Y4K3|TRAF6_HUMAN1.970e-621.65TNF receptor-associated factor 6 OS=Homo sapiens O... [more]
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BLAST of TNF receptor associated factor-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1E1014.845e-1629.25TRAF-6 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1[more]
I1ZID84.976e-1527.86TNF receptor associated factor-2 (Fragment) OS=Sch... [more]
T1DF651.291e-1329.10TRAF-2 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1[more]
A0A0F7GWW32.321e-832.58TNF receptor associated factor 4 (Fragment) OS=Sch... [more]
H0YW375.465e-824.68TNF receptor-associated factor OS=Taeniopygia gutt... [more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf2a2.300e-727.33TNF receptor-associated factor 2-like [Source:NCBI... [more]
traf2a2.611e-727.33TNF receptor-associated factor 2-like [Source:NCBI... [more]
traf13.801e-626.22TNF receptor-associated factor 1-like [Source:NCBI... [more]
traf2b3.916e-623.22TNF receptor associated factor 2 [Source:NCBI gene... [more]
traf14.668e-626.22TNF receptor-associated factor 1-like [Source:NCBI... [more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TNF receptor associated factor-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO487733.637e-623.26Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO483947.260e-619.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSORLT00000020861.21.810e-626.76TNF receptor-associated factor 2 [Source:NCBI gene... [more]
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BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000057298.10.000e+098.09SMESG000057298.1[more]
SMESG000009561.14.423e-3526.96SMESG000009561.1[more]
SMESG000024592.11.160e-3427.44SMESG000024592.1[more]
SMESG000009561.11.578e-3426.79SMESG000009561.1[more]
SMESG000014923.13.573e-3226.03SMESG000014923.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003487 ID=SMED30003487|Name=TNF receptor associated factor-2|organism=Schmidtea mediterranea sexual|type=transcript|length=1181bp
TTTGAAAACGCAAAAAAAGACTTATGGCCAACTCACAAGCTACTAATTTT
GATAAAATTTGGGAAGTGATTGGAAGGTTTGATTTTGACAAAGATCTCAA
ATTATCAGTCCATGTTGTATGCACAATATGCAACAAGCTACTGACCAACA
CCTACAAAGGTCCTTGCGGATGTAAATACTGCAAGAAATGTATTACCGAT
TATATAGGGAAAGAGAAGTTCTGTCCCGGTTCGGCAACTGATTGCAAATC
AAGAATCCTTTCATTTGAAGGCAATTTAATTAAAGATGACATAACAAACA
AACAAATTTCAAAACTTAGAATCAAATGCCCGTTGAATAAATGCAACTAT
GAAAATGAACTAATTCATGTAGCAGACCACATAGAAACTTGCAAATGTCT
TTCAAATCATTGCCCGTTTCTAACATTTGGTTGTCGATCTGTGAACTTGG
CCGACGAAGGAATTTCGGAGCATTTACAATCACATATTAATAATCACAAC
ACATTAATGGCCAGTTGGATGATGAACTTGAAGTCAAATGTGCTCGAACA
AATGGAAAGGTTTCAAATCCAAATGAAAAATCAAAGCCAGCGTTATGAAC
AAGAAATCTCAATTTTAAAAGAGAAATATTATAGACTTGAAAACGAAATC
TCACAACGGAAAACTCCATTTAATGATAACTTAAAGCAGACAAGTTCTGA
ACAACAAGACCTGGAAACCTCATTCAAGTGGATAGTATGCAACCTATCTC
AGAAACGTAAAGTCAATCATCATGTGATGAGCGGTTACTTTTATACATAT
AAAAAAGATTACGAAATGAGATTACGGTTGTGTCTTTCTGATCACCACAA
TCCTTCTGGGGGTGACATGAGTCTCAAATTTTTCATTCATAAAGGAAAAA
ATGATGTGGAAAGTATTTGGCCATTTAGAGGAAATATCTCTATTACGATG
AAGAATAAGGCAAATCTAAAGGCTGGTCTTCAAATATCAGAATATTGCAA
AATCCAGCAGCCAGTCTTAGGTTGTGATAGCTCGAAAGTTTTTGAGTTTC
CATTTGTGGACCTTCGCCGTTTGAAAGTTTTGGAAAGCGACTCAATAATC
ATTGAATGCAATATTACACTAAAATAAAAAGCTTTCTTAACTATTCGCTA
TTAAAATATTATTATATTTACTGTTATCTAC
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protein sequence of SMED30003487-orf-1

>SMED30003487-orf-1 ID=SMED30003487-orf-1|Name=SMED30003487-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=368bp
MANSQATNFDKIWEVIGRFDFDKDLKLSVHVVCTICNKLLTNTYKGPCGC
KYCKKCITDYIGKEKFCPGSATDCKSRILSFEGNLIKDDITNKQISKLRI
KCPLNKCNYENELIHVADHIETCKCLSNHCPFLTFGCRSVNLADEGISEH
LQSHINNHNTLMASWMMNLKSNVLEQMERFQIQMKNQSQRYEQEISILKE
KYYRLENEISQRKTPFNDNLKQTSSEQQDLETSFKWIVCNLSQKRKVNHH
VMSGYFYTYKKDYEMRLRLCLSDHHNPSGGDMSLKFFIHKGKNDVESIWP
FRGNISITMKNKANLKAGLQISEYCKIQQPVLGCDSSKVFEFPFVDLRRL
KVLESDSIIIECNITLK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR013083Znf_RING/FYVE/PHD
IPR008974TRAF-like
IPR001841Znf_RING
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0008270zinc ion binding
GO:0004842ubiquitin-protein transferase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0006955immune response
GO:0007165signal transduction
GO:0016567protein ubiquitination