slc30a-8

Overview


Name	slc30a-8 (AKN21628.1)
Smed ID	SMED30003463
Length (bp)	1361

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of slc30a-8 (SMED30003463) t-SNE clustered cells

Violin plots show distribution of expression levels for slc30a-8 (SMED30003463) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc30a-8 (SMED30003463) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc30a-8 (SMED30003463) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30003463

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30003463	SMESG000013136.1	dd_Smed_v4_5529_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30003463	SMESG000013136.1	dd_Smed_v4_5529_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30003463	SMESG000013136.1	dd_Smed_v4_5529_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30003463	SMESG000013136.1	dd_Smed_v6_5529_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of slc30a-8 vs. Ensembl Human
Match: SLC30A2 (solute carrier family 30 member 2 [Source:HGNC Symbol;Acc:HGNC:11013])

HSP 1 Score: 377.481 bits (968), Expect = 3.401e-128
Identity = 195/386 (50.52%), Postives = 262/386 (67.88%), Query Frame = 1

Query:  124 EHKEDQQVLIENDACINYYGS----STG---ITRTSSDF---------SDHCH---GPSEAIGVDK-NARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKS--EKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            E KE Q +L    A  +Y GS      G   + R   D          + HCH   GP       K  A+++L VAS +CL+FMIGE+VGG +A SLA+MTDAAHLLTDFAS +ISLF+++++SRPATK M+FGW RAE++GALVSVL IWVVTG+LVYLAV R++S +++I+GG MLITS   + +N+IM  TLHQ G               HGHSHG +  ++EN +VRAAFIHVIGD +QS+GV +AA ++Y KP+YK  DPICTF+FSILVL TT+ ILRD ++VLMEGTPK +DF  V+     + GV  +H+L +W+LT+++  LSVHIAI  + +   +L+ AS+ L+ +F    VTIQ+E+Y  +M +CQ CQ P+D
Sbjct:    2 EAKEKQHLLDARPAIRSYTGSLWQEGAGWIPLPRPGLDLQAIELAAQSNHHCHAQKGPDSHCDPKKGKAQRQLYVASAICLLFMIGEVVGGYLAHSLAVMTDAAHLLTDFASMLISLFSLWMSSRPATKTMNFGWQRAEILGALVSVLSIWVVTGVLVYLAVERLISGDYEIDGGTMLITSGCAVAVNIIMGLTLHQSG---------------HGHSHGTTNQQEENPSVRAAFIHVIGDFMQSMGVLVAAYILYFKPEYKYVDPICTFVFSILVLGTTLTILRDVILVLMEGTPKGVDFTAVRDLLLSVEGVEALHSLHIWALTVAQPVLSVHIAIAQNTDAQAVLKTASSRLQGKFHFHTVTIQIEDYSEDMKDCQACQGPSD 372

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BLAST of slc30a-8 vs. Ensembl Human
Match: SLC30A3 (solute carrier family 30 member 3 [Source:HGNC Symbol;Acc:HGNC:11014])

HSP 1 Score: 327.405 bits (838), Expect = 2.255e-108
Identity = 158/339 (46.61%), Postives = 225/339 (66.37%), Query Frame = 1

Query:  226 HCHG---PSEAIGVDK-NARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHG--HTHGSSKSNNETDKEHGHSHGKSEK---ENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            HCH    P   +  ++ +AR++L  A  +C +FM GE+VGG +A SLAIMTDAAHLL D  S M SLF+++L++RPAT+ M+FGWHR+E +GAL SV+ +W+VTGIL+YLA +R++  ++ IEGG ML+T+   +  NL+MA  LHQ G  H+HGS  +     +E     G  E     N +VRAAF+HV+GDL+QS GV  A+++IY KP+YK ADPI TF+FSI  L +T   LRD + +LMEGTP+++ F  V+     +PGV   H L +W+LT++    S H+AID   +   +L +AS+ L  RF  +  T+Q+E Y  EMA+C +CQ+P  
Sbjct:   54 HCHRDPLPPPGLTPERLHARRQLYAACAVCFVFMAGEVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWMVTGILLYLAFVRLLHSDYHIEGGAMLLTASIAVCANLLMAFVLHQAGPPHSHGSRGAEYAPLEE-----GPEEPLPLGNTSVRAAFVHVLGDLLQSFGVLAASILIYFKPQYKAADPISTFLFSICALGSTAPTLRDVLRILMEGTPRNVGFEPVRDTLLSVPGVRATHELHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPPQ 387

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BLAST of slc30a-8 vs. Ensembl Human
Match: SLC30A8 (solute carrier family 30 member 8 [Source:HGNC Symbol;Acc:HGNC:20303])

HSP 1 Score: 298.13 bits (762), Expect = 5.978e-98
Identity = 155/334 (46.41%), Postives = 227/334 (67.96%), Query Frame = 1

Query:  226 HCHGPSEAIGVDKN----ARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            HCH  S+      N    A+ KL  AS +C IFMI E+VGG +A SLA++TDAAHLL D  SF++SLF+++L+S+P +KR++FGWHRAE++GAL+S+L IWVVTG+LVYLA  R++  +++I+  +M+I S   +  N+++   LHQ               +  GH+H K  + N +VRAAF+H +GDL QSI V I+AL+IY KP+YKIADPICTFIFSILVL +TI IL+D  ++LMEG PK L+++ VK     + GV+ VH+L +WSLT+++  LS H+A    +++  + R+ +  L + F +  +TIQ+E+ V +  +C  C+DP D
Sbjct:    3 HCHSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTSFLLSLFSLWLSSKPPSKRLTFGWHRAEILGALLSILCIWVVTGVLVYLACERLLYPDYQIQATVMIIVSSCAVAANIVLTVVLHQ---------------RCLGHNH-KEVQANASVRAAFVHALGDLFQSISVLISALIIYFKPEYKIADPICTFIFSILVLASTITILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVATAASRDSQVVRREIAKALSKSFTMHSLTIQMESPVDQDPDCLFCEDPCD 320

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Query:  226 HCHGPSEAIGVDKN----ARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            HCH  S+      N    A+ KL  AS +C IFMI E+VGG +A SLA++TDAAHLL D  SF++SLF+++L+S+P +KR++FGWHRAE++GAL+S+L IWVVTG+LVYLA  R++  +++I+  +M+I S   +  N+++   LHQ               +  GH+H K  + N +VRAAF+H +GDL QSI V I+AL+IY KP+YKIADPICTFIFSILVL +TI IL+D  ++LMEG PK L+++ VK     + GV+ VH+L +WSLT+++  LS H+A    +++  + R+ +  L + F +  +TIQ+E+ V +  +C  C+DP D
Sbjct:    3 HCHSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTSFLLSLFSLWLSSKPPSKRLTFGWHRAEILGALLSILCIWVVTGVLVYLACERLLYPDYQIQATVMIIVSSCAVAANIVLTVVLHQ---------------RCLGHNH-KEVQANASVRAAFVHALGDLFQSISVLISALIIYFKPEYKIADPICTFIFSILVLASTITILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVATAASRDSQVVRREIAKALSKSFTMHSLTIQMESPVDQDPDCLFCEDPCD 320

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Query:  226 HCHGPSEAIGVDKN----ARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            HCH  S+      N    A+ KL  AS +C IFMI E+VGG +A SLA++TDAAHLL D  SF++SLF+++L+S+P +KR++FGWHRAE++GAL+S+L IWVVTG+LVYLA  R++  +++I+  +M+I S   +  N+++   LHQ               +  GH+H K  + N +VRAAF+H +GDL QSI V I+AL+IY KP+YKIADPICTFIFSILVL +TI IL+D  ++LMEG PK L+++ VK     + GV+ VH+L +WSLT+++  LS H+A    +++  + R+ +  L + F +  +TIQ+E+ V +  +C  C+DP D
Sbjct:    3 HCHSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTSFLLSLFSLWLSSKPPSKRLTFGWHRAEILGALLSILCIWVVTGVLVYLACERLLYPDYQIQATVMIIVSSCAVAANIVLTVVLHQ---------------RCLGHNH-KEVQANASVRAAFVHALGDLFQSISVLISALIIYFKPEYKIADPICTFIFSILVLASTITILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVATAASRDSQVVRREIAKALSKSFTMHSLTIQMESPVDQDPDCLFCEDPCD 320

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BLAST of slc30a-8 vs. Ensembl Celegans
Match: cdf-2 (Cation Diffusion Facilitator family [Source:UniProtKB/TrEMBL;Acc:A0A0K3AVP5])

HSP 1 Score: 340.117 bits (871), Expect = 2.862e-114
Identity = 171/361 (47.37%), Postives = 257/361 (71.19%), Query Frame = 1

Query:  136 DQQVLIENDACINYYGSSTGITRTSSDFSDHCHGPSEAIGV---DKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDP 1209
            ++  L+EN    + Y +  G   T +  + HCH  +++      ++ A + L +  +LCL FM+ E++GG +A SLAI+TDAAHLLTDFAS +ISLF++Y+A RP +++MSFG+HRAEV+GA  SV +IW+VTG+LV LA+MR+VS ++++EGGIM +T+  G+++NL+M A L+      G    ++     HGHSHG    +NINVRAAFIHV+GDL+QS+GV +AAL IY +P + I DPICT +FS++VL TTI ILRD M+VL+EG P ++DF +V ++  D+ GV +VH+LR+WSLT+ K ALSVH+ ID + ++ +ILR+   ML+Q + + ++TIQ+E + +  ++C +C  P
Sbjct:    4 ERAPLLEN-GVPHIYNTDEGRKTTVTYDNFHCHDEADSTDSHDSNRRATRILWLTVVLCLFFMVCEVIGGVLAGSLAIVTDAAHLLTDFASVLISLFSLYIARRPPSQKMSFGFHRAEVLGAFFSVFLIWIVTGVLVVLAIMRIVSGDYEVEGGIMALTAALGVVVNLVMLALLY-----FGGHSHSHGGGSSHGHSHGGGNGDNINVRAAFIHVLGDLLQSLGVLVAALFIYFQPSWVIIDPICTLVFSVIVLCTTIYILRDAMIVLLEGRPSNIDFAKVFSSLEDIEGVKKVHDLRIWSLTMDKIALSVHLEIDANSQSQSILRETRKMLKQTYNVHEITIQIEEFGANRSDCGKCDFP 358

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BLAST of slc30a-8 vs. Ensembl Celegans
Match: ttm-1 (Toxin-regulated Targets of MAPK [Source:UniProtKB/TrEMBL;Acc:A0A0K3AU82])

HSP 1 Score: 261.922 bits (668), Expect = 4.818e-83
Identity = 144/326 (44.17%), Postives = 209/326 (64.11%), Query Frame = 1

Query:  226 HCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQ 1203
            H H   E     + A K L   + L  +F+  E VGG  A SLAIMTDA H+L+D  SF+IS+FAI  A  PA+KR+SFG+ RAEV+GAL SV+++WV+T +LV +A+ R+V+ E +++  +MLIT+  G++ N++M   LH     HG +   + +           + +N+NVRAA IHVIGDLVQSIGV IAAL+I     + +ADPICTF+FSI+VL TT+ ++RD   VLME TP   D ++VK A   L GV  VH+L +WS+ + KTA SVH+A++        + +A +++R+RF +A  T+Q+E +  ++  C  CQ
Sbjct:   87 HKHSHDEKYQKGRRAEKVLWAVAALSAVFIAAEFVGGFWAQSLAIMTDAGHMLSDLLSFIISIFAIRCARLPASKRLSFGYERAEVLGALTSVIILWVLTTVLVVVAIQRIVNNEHEVDADVMLITAGVGVLFNIVMGLVLHFGTGGHGHTHGGHSSHGH------AHDGKNVNVRAALIHVIGDLVQSIGVLIAALIIRFT-GWTLADPICTFLFSIIVLFTTVTVMRDIFFVLMEATPSHYDLSDVKKALSALEGVKGVHDLHLWSIGMDKTAFSVHLALESPNRAMENVAEARSLIRRRFGVAVATVQVEPFDEKIDSCDTCQ 405

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BLAST of slc30a-8 vs. Ensembl Celegans
Match: ttm-1 (Toxin-regulated Targets of MAPK [Source:UniProtKB/TrEMBL;Acc:A0A0K3AU82])

HSP 1 Score: 259.225 bits (661), Expect = 6.002e-83
Identity = 144/314 (45.86%), Postives = 208/314 (66.24%), Query Frame = 1

Query:  262 KNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQ 1203
            + A K L   + L  +F+  E VGG  A SLAIMTDA H+L+D  SF+IS+FAI  A  PA+KR+SFG+ RAEV+GAL SV+++WV+T +LV +A+ R+V+ E +++  +MLIT+  G++ N++M   LH      G     +     HGH+H   + +N+NVRAA IHVIGDLVQSIGV IAAL+I     + +ADPICTF+FSI+VL TT+ ++RD   VLME TP   D ++VK A   L GV  VH+L +WS+ + KTA SVH+A++        + +A +++R+RF +A  T+Q+E +  ++  C  CQ
Sbjct:   22 RRAEKVLWAVAALSAVFIAAEFVGGFWAQSLAIMTDAGHMLSDLLSFIISIFAIRCARLPASKRLSFGYERAEVLGALTSVIILWVLTTVLVVVAIQRIVNNEHEVDADVMLITAGVGVLFNIVMGLVLHF---GTGGHGHTHGGHSSHGHAH---DGKNVNVRAALIHVIGDLVQSIGVLIAALIIRFT-GWTLADPICTFLFSIIVLFTTVTVMRDIFFVLMEATPSHYDLSDVKKALSALEGVKGVHDLHLWSIGMDKTAFSVHLALESPNRAMENVAEARSLIRRRFGVAVATVQVEPFDEKIDSCDTCQ 328

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BLAST of slc30a-8 vs. Ensembl Celegans
Match: ttm-1 (Toxin-regulated Targets of MAPK [Source:UniProtKB/TrEMBL;Acc:A0A0K3AU82])

HSP 1 Score: 259.61 bits (662), Expect = 2.198e-82
Identity = 144/314 (45.86%), Postives = 208/314 (66.24%), Query Frame = 1

Query:  262 KNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQ 1203
            + A K L   + L  +F+  E VGG  A SLAIMTDA H+L+D  SF+IS+FAI  A  PA+KR+SFG+ RAEV+GAL SV+++WV+T +LV +A+ R+V+ E +++  +MLIT+  G++ N++M   LH      G     +     HGH+H   + +N+NVRAA IHVIGDLVQSIGV IAAL+I     + +ADPICTF+FSI+VL TT+ ++RD   VLME TP   D ++VK A   L GV  VH+L +WS+ + KTA SVH+A++        + +A +++R+RF +A  T+Q+E +  ++  C  CQ
Sbjct:   80 RRAEKVLWAVAALSAVFIAAEFVGGFWAQSLAIMTDAGHMLSDLLSFIISIFAIRCARLPASKRLSFGYERAEVLGALTSVIILWVLTTVLVVVAIQRIVNNEHEVDADVMLITAGVGVLFNIVMGLVLHF---GTGGHGHTHGGHSSHGHAH---DGKNVNVRAALIHVIGDLVQSIGVLIAALIIRF-TGWTLADPICTFLFSIIVLFTTVTVMRDIFFVLMEATPSHYDLSDVKKALSALEGVKGVHDLHLWSIGMDKTAFSVHLALESPNRAMENVAEARSLIRRRFGVAVATVQVEPFDEKIDSCDTCQ 386

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BLAST of slc30a-8 vs. Ensembl Celegans
Match: Y105E8A.3 (pep chromosome:WBcel235:I:14358502:14367594:1 gene:WBGene00013668.1 transcript:Y105E8A.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y105E8A.3)

HSP 1 Score: 69.3218 bits (168), Expect = 2.480e-12
Identity = 81/351 (23.08%), Postives = 155/351 (44.16%), Query Frame = 1

Query:  124 EHKEDQQVLIENDACINYYGSSTGITRTSSDFSDHCHGPSEAIGVDKNARKKLLVASILC--LIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ-HGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLEN 1167
            +H+    V I N     +      + RTS             I ++ ++R+   +   LC  L F   E + G   +SL +++D  H+L D ++ ++ L A  +A  P T+  +FG+ R E++   ++ L + V+   ++  A+ R+      I    +L  +I+G+I+NL    +L +      G S   +       H H      N N++  F+HV+ D + S+ V I+ L+I     +   DP+C+ I S+L++ +   +L  ++  L++  P++ +F        ++  V    N  MW         SVH+ +  +     I    SN+L+        T+Q+E 
Sbjct:  353 KHRGGHFVGISNTGLPLFTYGEAFLQRTSKSLMLFMKETLNEILMNNDSRR---IFWFLCVNLGFCGVEFLYGFWTNSLGLISDGFHMLFDCSALVMGLVASVMARWPPTRHFTFGFGRVEILSGFINALFLCVIALFILIEALERLFDPP-NINTDRLLFVAISGLIVNLFGMYSLGEHGHSHGGGSSHGHSHGGGGSHGHSHGGGGNANMQGVFLHVLADTLGSVFVIISTLLIQWF-GWVWVDPLCSLILSLLIIGSVYPLLVSSISTLLQDVPEEEEFEYHINEILEIEHVESYSNAHMWQHKSDINVASVHVQVKEEANAQMIRHRVSNILKST-GATHSTVQVEK 697

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BLAST of slc30a-8 vs. Ensembl Fly
Match: ZnT33D (gene:FBgn0051860 transcript:FBtr0302984)

HSP 1 Score: 342.813 bits (878), Expect = 8.380e-111
Identity = 177/357 (49.58%), Postives = 247/357 (69.19%), Query Frame = 1

Query:  190 TGITRTSSDFSDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTH---GSSKSNNETDKEHGHSH----GKS--------EKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            TG +  ++ +  HCH      GVDK AR+ L++A ILC IF+I E++GG +++SLAI TDAAHLLTD ASF+IS+ A++LA RP+++R+++GWHRAEV+GA+VS+  IWVVTGILVY+A+MR V+ +F+++  IMLITS   I+ N+IMA  L QHGH+H   G  K + +     G       GKS          ENINVRAA IHV+GD++QS GVF+AAL+I+  P++   D +CTF+FS+LVL+ T  ILRD ++VLME TP  +D+ EVK  F  + GV  VHNLR+W+L+I+K ALS H+AI  D +   IL +A+ ++ +RF+  + TIQ+E Y   M  C QC  P+D
Sbjct:  311 TGHSHITAKWDGHCHFKERETGVDKAARRVLIIACILCTIFLILEVIGGILSNSLAIATDAAHLLTDLASFLISISALHLAGRPSSERLNYGWHRAEVIGAMVSIFFIWVVTGILVYMAIMRWVNQDFELDAKIMLITSALAILFNVIMAMQL-QHGHSHSLPGVHKMSKDAGSVLGSKMILLLGKSVSMQYAAKGHENINVRAAIIHVVGDIIQSFGVFVAALIIFFWPEWAFMDSVCTFVFSVLVLVVTFKILRDVLMVLMEATPDFMDYEEVKQTFLSISGVEHVHNLRIWALSINKVALSAHLAISKDADPQLILEEATTLIHKRFKFFETTIQIEEYSPGMENCGQCLSPSD 666

[Close]

BLAST of slc30a-8 vs. Ensembl Fly
Match: ZnT35C (gene:FBgn0028516 transcript:FBtr0080715)

HSP 1 Score: 194.126 bits (492), Expect = 1.291e-56
Identity = 96/170 (56.47%), Postives = 131/170 (77.06%), Query Frame = 1

Query:  157 NDACINYYGSSTGITRTSSDF-----SDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLH 651
            NDA + Y  ++T + ++  +       DHCH  + + GVD  AR+KL++ASILCL+FMI EIVGG +++SLAI TDAAHLLTDFASFMISLFAI++A RP+T+RMSFGW+RAEV+GA+ SV MIWV+TGILV+LA+ R++S ++++   IMLITS   I++N+IM   L 
Sbjct:   15 NDARL-YRNAATSLDKSRLEMLHEYVRDHCHR-ARSEGVDVKARRKLIIASILCLVFMIAEIVGGVLSNSLAIATDAAHLLTDFASFMISLFAIWIAGRPSTQRMSFGWYRAEVIGAMASVFMIWVITGILVWLAIGRLISGDYEVNAKIMLITSGLAILVNVIMGVQLQ 182

HSP 2 Score: 180.259 bits (456), Expect = 2.253e-51
Identity = 85/168 (50.60%), Postives = 116/168 (69.05%), Query Frame = 1

Query:  706 HGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDP 1209
            HG   G+ E  N+NVRAA IHVIGD++QS+GVF+AA VIY  P+Y I DPICTF+FSI+VL TT  I++D ++VLMEGTP  + + EV   F  + GV  VHNLR+W+L+I+K ALS H+AI  +     IL  A++ +  R+   + TIQ+E+Y ++M  C QC  P
Sbjct:  272 HGGPVGR-EAVNMNVRAALIHVIGDVIQSVGVFVAAGVIYFWPEYSIVDPICTFVFSIIVLFTTFTIMKDALLVLMEGTPNYMHYAEVLQIFQGIEGVERVHNLRIWALSINKVALSAHLAIAENANPKRILDAATSAVHLRYNFFETTIQIEDYTAQMESCLQCNVP 438

[Close]

BLAST of slc30a-8 vs. Ensembl Fly
Match: ZnT35C (gene:FBgn0028516 transcript:FBtr0080714)

HSP 1 Score: 193.741 bits (491), Expect = 3.122e-56
Identity = 91/146 (62.33%), Postives = 120/146 (82.19%), Query Frame = 1

Query:  214 DFSDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLH 651
            +  DHCH  + + GVD  AR+KL++ASILCL+FMI EIVGG +++SLAI TDAAHLLTDFASFMISLFAI++A RP+T+RMSFGW+RAEV+GA+ SV MIWV+TGILV+LA+ R++S ++++   IMLITS   I++N+IM   L 
Sbjct:   70 EVRDHCHR-ARSEGVDVKARRKLIIASILCLVFMIAEIVGGVLSNSLAIATDAAHLLTDFASFMISLFAIWIAGRPSTQRMSFGWYRAEVIGAMASVFMIWVITGILVWLAIGRLISGDYEVNAKIMLITSGLAILVNVIMGVQLQ 214

HSP 2 Score: 179.104 bits (453), Expect = 9.741e-51
Identity = 85/168 (50.60%), Postives = 116/168 (69.05%), Query Frame = 1

Query:  706 HGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDP 1209
            HG   G+ E  N+NVRAA IHVIGD++QS+GVF+AA VIY  P+Y I DPICTF+FSI+VL TT  I++D ++VLMEGTP  + + EV   F  + GV  VHNLR+W+L+I+K ALS H+AI  +     IL  A++ +  R+   + TIQ+E+Y ++M  C QC  P
Sbjct:  304 HGGPVGR-EAVNMNVRAALIHVIGDVIQSVGVFVAAGVIYFWPEYSIVDPICTFVFSIIVLFTTFTIMKDALLVLMEGTPNYMHYAEVLQIFQGIEGVERVHNLRIWALSINKVALSAHLAIAENANPKRILDAATSAVHLRYNFFETTIQIEDYTAQMESCLQCNVP 470

[Close]

BLAST of slc30a-8 vs. Ensembl Fly
Match: ZnT33D (gene:FBgn0051860 transcript:FBtr0302985)

HSP 1 Score: 144.05 bits (362), Expect = 5.815e-38
Identity = 63/113 (55.75%), Postives = 89/113 (78.76%), Query Frame = 1

Query:  190 TGITRTSSDFSDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTG 528
            TG +  ++ +  HCH      GVDK AR+ L++A ILC IF+I E++GG +++SLAI TDAAHLLTD ASF+IS+ A++LA RP+++R+++GWHRAEV+GA+VS+  IWVVTG
Sbjct:  311 TGHSHITAKWDGHCHFKERETGVDKAARRVLIIACILCTIFLILEVIGGILSNSLAIATDAAHLLTDLASFLISISALHLAGRPSSERLNYGWHRAEVIGAMVSIFFIWVVTG 423

[Close]

BLAST of slc30a-8 vs. Ensembl Fly
Match: ZnT41F (gene:FBgn0025693 transcript:FBtr0086054)

HSP 1 Score: 134.42 bits (337), Expect = 2.996e-34
Identity = 64/130 (49.23%), Postives = 93/130 (71.54%), Query Frame = 1

Query:  262 KNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLH 651
            + A+ K+++A  LC +FMI E +GG +A SLAIMTDAAHL +D  SF+I L AI++  RP  +RMSFG+ R EV+GAL S+L IW VT +LV +A+ R+ S +F++   +M++ S  GI+IN++M   LH
Sbjct:  127 QEAKYKIMLAVALCCVFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIWFVTTLLVVVAIERIFSQDFELNADMMMLISGIGIVINIVMMFVLH 256

HSP 2 Score: 120.553 bits (301), Expect = 2.391e-29
Identity = 59/146 (40.41%), Postives = 96/146 (65.75%), Query Frame = 1

Query:  730 EKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQ-RFQIADVTIQLE 1164
            E +N+N+RAA IHVIGDLVQSIGVF+AA++I + P  K ADP+CT IFSI+V++TT+ + R+++ +++   P++L+   +      + GV  +H+L +W  T  +  L VH+  D   + + +L+ A+ ++   R+ I   TIQLE
Sbjct:  349 EDKNLNLRAAMIHVIGDLVQSIGVFLAAVLIKVCPGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIVNAVPQNLNMRTLHLELGSIEGVRSLHHLNVWQQTSQQRVLMVHLVTDSRADGNEVLQAATALVSSPRYNIKHSTIQLE 494

[Close]

BLAST of slc30a-8 vs. Ensembl Zebrafish
Match: slc30a2 (solute carrier family 30 member 2 [Source:ZFIN;Acc:ZDB-GENE-041014-347])

HSP 1 Score: 376.711 bits (966), Expect = 1.036e-127
Identity = 183/383 (47.78%), Postives = 257/383 (67.10%), Query Frame = 1

Query:  106 RGAIFHEHKEDQQVLIENDACINY---YGSSTGITRTSSDFSDHCHGPSEAIGVDKN---ARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHG--HTHGSS----KSNNETDKEHGHSHGK-SEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            R A  +  K + +     ++C N     G   G          HCHG   A    +    A+KKL +ASI+CL+FMIGE++GG +A SLAIMTDAAHLLTDF S M+SLF+++++SRP TK M+FGWHR+E++GAL+SV+ IW+VTG+LVYLA+ R+V  +++IEG +ML+TS   +++N+IMA  LH     H+HGS       +  +   HGHSH       N +VRAAFIHV+GDL+QS GV +AA++IY +P+YKIADPICTF+FS+ VL TT+ ILRD   +LMEG PK + FN VK     L  V  +H+L +W+LT+S++ LSVHIAI+ + +  ++L++A+ +L+ +F     TIQ+E Y  +M  C QCQDP D
Sbjct:   16 RNAKIYSLKLNSEFSGSKESCPNLPLGNGEMAGAIELKRPVGTHCHGKKAAYDDSREKLLAKKKLFIASIVCLVFMIGEVIGGYLAHSLAIMTDAAHLLTDFGSMMVSLFSLWISSRPPTKIMNFGWHRSEILGALISVMSIWIVTGVLVYLAIERIVKNDYEIEGRVMLLTSGCAVVVNIIMAYILHHSTTFHSHGSGYHKIDESGMSPVGHGHSHSLLGNHGNTSVRAAFIHVLGDLLQSFGVMVAAIIIYFRPEYKIADPICTFLFSVFVLATTLTILRDVFRILMEGAPKGIQFNSVKEVLLSLKAVKAMHSLHLWALTLSQSLLSVHIAIEENADPQSVLKEATELLQTKFGFYSTTIQVEPYSEDMIHCTQCQDPMD 398

[Close]

BLAST of slc30a-8 vs. Ensembl Zebrafish
Match: slc30a2 (solute carrier family 30 member 2 [Source:ZFIN;Acc:ZDB-GENE-041014-347])

HSP 1 Score: 374.015 bits (959), Expect = 2.292e-127
Identity = 176/340 (51.76%), Postives = 245/340 (72.06%), Query Frame = 1

Query:  226 HCHGPSEAIGVDKN---ARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHG--HTHGSS----KSNNETDKEHGHSHGK-SEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            HCHG   A    +    A+KKL +ASI+CL+FMIGE++GG +A SLAIMTDAAHLLTDF S M+SLF+++++SRP TK M+FGWHR+E++GAL+SV+ IW+VTG+LVYLA+ R+V  +++IEG +ML+TS   +++N+IMA  LH     H+HGS       +  +   HGHSH       N +VRAAFIHV+GDL+QS GV +AA++IY +P+YKIADPICTF+FS+ VL TT+ ILRD   +LMEG PK + FN VK     L  V  +H+L +W+LT+S++ LSVHIAI+ + +  ++L++A+ +L+ +F     TIQ+E Y  +M  C QCQDP D
Sbjct:   14 HCHGKKAAYDDSREKLLAKKKLFIASIVCLVFMIGEVIGGYLAHSLAIMTDAAHLLTDFGSMMVSLFSLWISSRPPTKIMNFGWHRSEILGALISVMSIWIVTGVLVYLAIERIVKNDYEIEGRVMLLTSGCAVVVNIIMAYILHHSTTFHSHGSGYHKIDESGMSPVGHGHSHSLLGNHGNTSVRAAFIHVLGDLLQSFGVMVAAIIIYFRPEYKIADPICTFLFSVFVLATTLTILRDVFRILMEGAPKGIQFNSVKEVLLSLKAVKAMHSLHLWALTLSQSLLSVHIAIEENADPQSVLKEATELLQTKFGFYSTTIQVEPYSEDMIHCTQCQDPMD 353

[Close]

BLAST of slc30a-8 vs. Ensembl Zebrafish
Match: slc30a2 (solute carrier family 30 member 2 [Source:ZFIN;Acc:ZDB-GENE-041014-347])

HSP 1 Score: 363.229 bits (931), Expect = 1.831e-123
Identity = 172/334 (51.50%), Postives = 238/334 (71.26%), Query Frame = 1

Query:  226 HCHGPSEAIGVDKN---ARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHG-KSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            HCHG   A    +    A+KKL +ASI+CL+FMIGE++GG +A SLAIMTDAAHLLTDF S M+SLF+++++SRP TK M+FGWHR+E++GAL+SV+ IW+VTG+LVYLA+ R+V  +++IEG +ML+TS   +++N+I       HG  +     +  +   HGHSH       N +VRAAFIHV+GDL+QS GV +AA++IY +P+YKIADPICTF+FS+ VL TT+ ILRD   +LMEG PK + FN VK     L  V  +H+L +W+LT+S++ LSVHIAIDP     ++L++A+ +L+ +F     TIQ+E Y  +M  C QCQDP D
Sbjct:   14 HCHGKKAAYDDSREKLLAKKKLFIASIVCLVFMIGEVIGGYLAHSLAIMTDAAHLLTDFGSMMVSLFSLWISSRPPTKIMNFGWHRSEILGALISVMSIWIVTGVLVYLAIERIVKNDYEIEGRVMLLTSGCAVVVNII-------HGSGYHKIDESGMSPVGHGHSHSLLGNHGNTSVRAAFIHVLGDLLQSFGVMVAAIIIYFRPEYKIADPICTFLFSVFVLATTLTILRDVFRILMEGAPKGIQFNSVKEVLLSLKAVKAMHSLHLWALTLSQSLLSVHIAIDPQ----SVLKEATELLQTKFGFYSTTIQVEPYSEDMIHCTQCQDPMD 336

[Close]

BLAST of slc30a-8 vs. Ensembl Zebrafish
Match: slc30a8 (solute carrier family 30 member 8 [Source:ZFIN;Acc:ZDB-GENE-060315-10])

HSP 1 Score: 352.829 bits (904), Expect = 1.708e-118
Identity = 175/360 (48.61%), Postives = 248/360 (68.89%), Query Frame = 1

Query:  208 SSDFSD--HCHGPSEAI----GVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--HGHTHGSSKS----NNETDKEHGHSH-------------GKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPA 1212
            S D  D  HCH  + A+       K A+K+L + S +CL+FM+GEI+GG  A SLA+MTDAAHLL D  SF+ISL +++L+SRPAT+ +++GWHRAE++GAL+S+  IW+VTG+LVYLAV R+++  F IEG +MLITS   ++ N+IMA TLHQ  HGH+HG   +    +++  KE+GHSH             GK++  N +VRAAF+HVIGDL+QSI V ++AL+I+ KP+YKIADPICTF+FS+ VL TT  I+RD ++VLMEGTP  +++NEV+     + GV  VHNL +W+LT+++  LS H+A D   +   +LR+ + +   ++    VTIQLE    +  +C  CQDPA
Sbjct:   29 SVDMKDGKHCHDNNRALEDREREKKIAKKRLYIVSAVCLVFMVGEILGGYFAGSLAVMTDAAHLLVDLTSFIISLCSLWLSSRPATRTLNYGWHRAEILGALLSIFTIWLVTGVLVYLAVERIINDNFTIEGTVMLITSGCAVLANIIMALTLHQSGHGHSHGGLSAGHGHSHDHGKENGHSHSDGSHHDVEEQRPGKTQA-NASVRAAFVHVIGDLLQSISVLVSALIIFFKPEYKIADPICTFLFSLFVLGTTFTIMRDIVIVLMEGTPAGVNYNEVRQLLLGVKGVKAVHNLHIWALTMNQAVLSAHVATDETVDPQEVLREMTQVCFTKYSFHSVTIQLEPQADQRPDCSLCQDPA 387

[Close]

BLAST of slc30a-8 vs. Ensembl Zebrafish
Match: slc30a8 (solute carrier family 30 member 8 [Source:ZFIN;Acc:ZDB-GENE-060315-10])

HSP 1 Score: 352.443 bits (903), Expect = 1.780e-118
Identity = 176/364 (48.35%), Postives = 250/364 (68.68%), Query Frame = 1

Query:  196 ITRTSSDFSD--HCHGPSEAI----GVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--HGHTHGSSKS----NNETDKEHGHSH-------------GKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPA 1212
            I   S D  D  HCH  + A+       K A+K+L + S +CL+FM+GEI+GG  A SLA+MTDAAHLL D  SF+ISL +++L+SRPAT+ +++GWHRAE++GAL+S+  IW+VTG+LVYLAV R+++  F IEG +MLITS   ++ N+IMA TLHQ  HGH+HG   +    +++  KE+GHSH             GK++  N +VRAAF+HVIGDL+QSI V ++AL+I+ KP+YKIADPICTF+FS+ VL TT  I+RD ++VLMEGTP  +++NEV+     + GV  VHNL +W+LT+++  LS H+ +DP +    +LR+ + +   ++    VTIQLE    +  +C  CQDPA
Sbjct:   23 IIMPSVDMKDGKHCHDNNRALEDREREKKIAKKRLYIVSAVCLVFMVGEILGGYFAGSLAVMTDAAHLLVDLTSFIISLCSLWLSSRPATRTLNYGWHRAEILGALLSIFTIWLVTGVLVYLAVERIINDNFTIEGTVMLITSGCAVLANIIMALTLHQSGHGHSHGGLSAGHGHSHDHGKENGHSHSDGSHHDVEEQRPGKTQA-NASVRAAFVHVIGDLLQSISVLVSALIIFFKPEYKIADPICTFLFSLFVLGTTFTIMRDIVIVLMEGTPAGVNYNEVRQLLLGVKGVKAVHNLHIWALTMNQAVLSAHVTVDPQE----VLREMTQVCFTKYSFHSVTIQLEPQADQRPDCSLCQDPA 381

[Close]

BLAST of slc30a-8 vs. Ensembl Xenopus
Match: slc30a2 (solute carrier family 30 member 2 [Source:NCBI gene;Acc:448552])

HSP 1 Score: 410.609 bits (1054), Expect = 2.831e-141
Identity = 195/338 (57.69%), Postives = 257/338 (76.04%), Query Frame = 1

Query:  220 SDHCHGPSEAIGVD----KNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--HGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            + HCH   E    +    K AR+KL VAS +CL+FMIGE++GG +A SLAIMTDAAHLLTDFAS MISLFA++++SRPATK M+FGWHRAE++GAL+SVL IWVVTG+LVYLAV R++S +++IEG  MLITS   + +N+IM  TLHQ  HGH+HG   S       H HSH   + +N +VRAAFIHV+GDL+QS+GV IAA VIY KP+YKI DPICTF+FS+LVLITT+ ILRD ++VLMEGTPK +DFN VK     + GV  +H+L +W+LT+++  LSVHIAI+ + ++  +L++AS+ L+ +F     TIQ+ENY  +M +CQ+CQDP+D
Sbjct:   47 NQHCHSNRELDDWNAKEKKRARRKLYVASAVCLVFMIGEVIGGYLAHSLAIMTDAAHLLTDFASMMISLFALWMSSRPATKTMNFGWHRAEILGALLSVLSIWVVTGVLVYLAVERIISGDYEIEGDAMLITSACAVAVNIIMGVTLHQTGHGHSHGDGNS-------HSHSHAAGDHKNPSVRAAFIHVVGDLLQSVGVLIAAYVIYYKPEYKIIDPICTFLFSVLVLITTLTILRDVLLVLMEGTPKGVDFNLVKDTLLSIDGVKALHSLHIWALTVTQPVLSVHIAINENADSQKVLKEASSQLQNKFHFHTTTIQIENYSDDMKDCQECQDPSD 377

[Close]

BLAST of slc30a-8 vs. Ensembl Xenopus
Match: slc30a2 (solute carrier family 30 member 2 [Source:NCBI gene;Acc:448552])

HSP 1 Score: 410.609 bits (1054), Expect = 3.162e-141
Identity = 195/338 (57.69%), Postives = 257/338 (76.04%), Query Frame = 1

Query:  220 SDHCHGPSEAIGVD----KNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--HGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            + HCH   E    +    K AR+KL VAS +CL+FMIGE++GG +A SLAIMTDAAHLLTDFAS MISLFA++++SRPATK M+FGWHRAE++GAL+SVL IWVVTG+LVYLAV R++S +++IEG  MLITS   + +N+IM  TLHQ  HGH+HG   S       H HSH   + +N +VRAAFIHV+GDL+QS+GV IAA VIY KP+YKI DPICTF+FS+LVLITT+ ILRD ++VLMEGTPK +DFN VK     + GV  +H+L +W+LT+++  LSVHIAI+ + ++  +L++AS+ L+ +F     TIQ+ENY  +M +CQ+CQDP+D
Sbjct:   48 NQHCHSNRELDDWNAKEKKRARRKLYVASAVCLVFMIGEVIGGYLAHSLAIMTDAAHLLTDFASMMISLFALWMSSRPATKTMNFGWHRAEILGALLSVLSIWVVTGVLVYLAVERIISGDYEIEGDAMLITSACAVAVNIIMGVTLHQTGHGHSHGDGNS-------HSHSHAAGDHKNPSVRAAFIHVVGDLLQSVGVLIAAYVIYYKPEYKIIDPICTFLFSVLVLITTLTILRDVLLVLMEGTPKGVDFNLVKDTLLSIDGVKALHSLHIWALTVTQPVLSVHIAINENADSQKVLKEASSQLQNKFHFHTTTIQIENYSDDMKDCQECQDPSD 378

[Close]

BLAST of slc30a-8 vs. Ensembl Xenopus
Match: ENSXETT00000033890.1 (solute carrier family 30 (zinc transporter), member 3 [Source:NCBI gene;Acc:100497671])

HSP 1 Score: 369.392 bits (947), Expect = 9.585e-125
Identity = 177/341 (51.91%), Postives = 241/341 (70.67%), Query Frame = 1

Query:  226 HCHGPSEAIGVDKN---ARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ----HGHTHGSS------KSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDP 1209
            HCHG S +         AR+KL  A  +C IFMIGE+VGG++A SLAIMTDAAHLLTD  S  +S+F++++++RP TK M+FGWHR+E++GAL SVL IW+VTG+LVYLA  R+++ ++ I+G +MLITS   + +N+IMA  LHQ    HGH+HGS         +N      G  HG     N +VRAAFIHVIGDL+QSIGV +AA+VIY KP+YKIADP+CTF+FSI VL TT+ ILRD   VLMEG P+ + +  VK     + GV  VH+LR+W+LT+S+ A++VH+AID   E  + +R+A+ +LR +F++   T+Q+E Y+ EM EC QC+DP
Sbjct:   58 HCHGASLSSAETNQKLQARRKLYFACAVCFIFMIGEVVGGSLAHSLAIMTDAAHLLTDLGSMCVSIFSLWISTRPPTKSMNFGWHRSEILGALASVLSIWIVTGVLVYLAAARIINNDYDIDGHVMLITSGCAVGVNVIMAYILHQSSPLHGHSHGSGYEKIGESPSNSLALRLGGPHG-----NTSVRAAFIHVIGDLLQSIGVMVAAIVIYFKPQYKIADPLCTFLFSIFVLATTVTILRDVFWVLMEGAPRGIAYGSVKEVLLSVRGVRSVHSLRLWALTLSQNAVTVHLAIDESTEPESAVREATELLRSQFELCHSTVQVERYLEEMEECPQCRDP 393

[Close]

BLAST of slc30a-8 vs. Ensembl Xenopus
Match: nbr1 (neighbor of BRCA1 gene 1 [Source:Xenbase;Acc:XB-GENE-949692])

HSP 1 Score: 331.257 bits (848), Expect = 3.335e-110
Identity = 165/338 (48.82%), Postives = 232/338 (68.64%), Query Frame = 1

Query:  226 HCHGPSEAIGVDKN-----ARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--HGHTHGSSKSNNETDKEHGHSHGKSE---KENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDP 1209
            HCH  ++     +      A+KKL +AS++C +F+  EIVGG +A SLA++TDAAHLL D +SF ISL +++L+S+ +T R++FGWHRAE++GAL+SV+ IW+VTG+LVYLA  R++  ++ I+G +MLITS   +  NL++A  LHQ  HGH+H   K          H H  SE   + N ++RAAFIHVIGDL QSI V I+AL+IY KP+YK+ADPICTFIFSI VLITT+ +LRD + VLMEGTP+ + +++VK +  D+ GV  VH+L +W+LT+++  LS HIA D   E+  IL+D +  +  RF    VTIQ+E    +  EC  C +P
Sbjct:   45 HCHNNNKKAYDARQREQTFAKKKLCIASLICFVFISAEIVGGYIAGSLAVVTDAAHLLVDLSSFFISLCSLWLSSKSSTTRLTFGWHRAEILGALMSVITIWLVTGVLVYLACERLIRPDYTIDGTVMLITSACALGANLVLALILHQSGHGHSHAGGK----------HEHMASEYKPQTNASIRAAFIHVIGDLFQSISVLISALIIYFKPEYKMADPICTFIFSIFVLITTVTVLRDLLTVLMEGTPRGIHYSDVKQSILDVDGVKSVHSLHLWALTMNQVILSAHIATDIVGESKRILKDVTQNVFARFPFHSVTIQVEPIEDQSPECMFCYEP 372

[Close]

BLAST of slc30a-8 vs. Ensembl Xenopus
Match: gmip (GEM interacting protein [Source:Xenbase;Acc:XB-GENE-977540])

HSP 1 Score: 256.529 bits (654), Expect = 2.025e-80
Identity = 139/339 (41.00%), Postives = 218/339 (64.31%), Query Frame = 1

Query:  199 TRTSSDFSDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ-HGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQET--HTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQD 1206
             R  ++  + C    E     K  ++KLL+A+ L L+FM+GE+VGG +A+SLAIMTDA H+L+D +S +++L A+ L+S+P  KR +FG+HR EV+ A+VSV++++++TG L+Y A+ R + M++ I G +MLIT+  G+ +NLIM   L Q   H   S      +   HGHSHG     ++ VRAAF+H +GDL QSIGV IAA +I  KP+YKIADPICT+IFS+LV+ TT+ ++ DT+++++EG P+ L+ + +K     +  V  V +L +WSLT  K+A  +H+ + PD  +    +   A ++L +   +    IQ+++Y  E  E  +C D
Sbjct:   86 NRVKTEPCEKCSNHRERRKQGK-VKRKLLLAAALYLLFMVGELVGGYVANSLAIMTDALHMLSDLSSIILTLLALCLSSKPPNKRFTFGFHRLEVLSAIVSVILVYILTGFLLYEAIQRTIHMDYNINGDVMLITAAVGVAVNLIMGILLSQSGHHHSHSHGPAANSPSPHGHSHG-----SLAVRAAFVHALGDLAQSIGVLIAAYIIRFKPEYKIADPICTYIFSVLVVFTTVRLVWDTVLIILEGVPRHLNVDRIKDDLMKIEDVYSVKDLNVWSLTTGKSAAIIHLQLCPDASSKWEEVQNKARHVLLKTHGMYKCFIQIQSYGQE--ESTRCTD 416

[Close]

BLAST of slc30a-8 vs. Ensembl Mouse
Match: Slc30a2 (solute carrier family 30 (zinc transporter), member 2 [Source:MGI Symbol;Acc:MGI:106637])

HSP 1 Score: 374.4 bits (960), Expect = 3.425e-127
Identity = 179/320 (55.94%), Postives = 241/320 (75.31%), Query Frame = 1

Query:  262 KNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--HGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            + AR+KL VAS +CL+FMIGEI+GG +A SLAIMTDAAHLLTDFAS +ISLFA++++SRPATK M+FGWHRAE++GAL+SVL IWVVTG+LVYLAV R++S +++I+G  MLITS   + +NLIM   LHQ  HGH+HG+S+ ++            S+++N +VRAAFIHVIGDL+QS+GV +AA +IY KP+YK  DPICTF+FSILVL TT+ ILRD ++VLMEGTPK +DF  VK     + GV  +H+L +W+LT+++  LSVHIAI  + +   +L+ A + L+ +F    +TIQ+E Y  +M  CQ CQ P +
Sbjct:   64 QRARRKLYVASAICLVFMIGEIIGGYLAQSLAIMTDAAHLLTDFASMLISLFALWVSSRPATKTMNFGWHRAEILGALLSVLSIWVVTGVLVYLAVQRLISGDYEIKGDTMLITSGCAVAVNLIMGLALHQSGHGHSHGNSRDDS------------SQQQNPSVRAAFIHVIGDLLQSVGVLVAAYIIYFKPEYKYVDPICTFLFSILVLGTTLTILRDVILVLMEGTPKGVDFTTVKNLLLSVDGVEALHSLHIWALTVAQPVLSVHIAIAQNADAQAVLKVARDRLQGKFNFHTMTIQIEKYSEDMKNCQACQGPLE 371

[Close]

BLAST of slc30a-8 vs. Ensembl Mouse
Match: Slc30a2 (solute carrier family 30 (zinc transporter), member 2 [Source:MGI Symbol;Acc:MGI:106637])

HSP 1 Score: 351.673 bits (901), Expect = 1.869e-119
Identity = 169/303 (55.78%), Postives = 227/303 (74.92%), Query Frame = 1

Query:  313 MIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--HGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            MIGEI+GG +A SLAIMTDAAHLLTDFAS +ISLFA++++SRPATK M+FGWHRAE++GAL+SVL IWVVTG+LVYLAV R++S +++I+G  MLITS   + +NLIM   LHQ  HGH+HG+S+ ++            S+++N +VRAAFIHVIGDL+QS+GV +AA +IY KP+YK  DPICTF+FSILVL TT+ ILRD ++VLMEGTPK +DF  VK     + GV  +H+L +W+LT+++  LSVHIAI  + +   +L+ A + L+ +F    +TIQ+E Y  +M  CQ CQ P +
Sbjct:    1 MIGEIIGGYLAQSLAIMTDAAHLLTDFASMLISLFALWVSSRPATKTMNFGWHRAEILGALLSVLSIWVVTGVLVYLAVQRLISGDYEIKGDTMLITSGCAVAVNLIMGLALHQSGHGHSHGNSRDDS------------SQQQNPSVRAAFIHVIGDLLQSVGVLVAAYIIYFKPEYKYVDPICTFLFSILVLGTTLTILRDVILVLMEGTPKGVDFTTVKNLLLSVDGVEALHSLHIWALTVAQPVLSVHIAIAQNADAQAVLKVARDRLQGKFNFHTMTIQIEKYSEDMKNCQACQGPLE 291

[Close]

Query:  313 MIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--HGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            MIGEI+GG +A SLAIMTDAAHLLTDFAS +ISLFA++++SRPATK M+FGWHRAE++GAL+SVL IWVVTG+LVYLAV R++S +++I+G  MLITS   + +NLIM   LHQ  HGH+HG+S+ ++            S+++N +VRAAFIHVIGDL+QS+GV +AA +IY KP+YK  DPICTF+FSILVL TT+ ILRD ++VLMEGTPK +DF  VK     + GV  +H+L +W+LT+++  LSVHIAI  + +   +L+ A + L+ +F    +TIQ+E Y  +M  CQ CQ P +
Sbjct:    1 MIGEIIGGYLAQSLAIMTDAAHLLTDFASMLISLFALWVSSRPATKTMNFGWHRAEILGALLSVLSIWVVTGVLVYLAVQRLISGDYEIKGDTMLITSGCAVAVNLIMGLALHQSGHGHSHGNSRDDS------------SQQQNPSVRAAFIHVIGDLLQSVGVLVAAYIIYFKPEYKYVDPICTFLFSILVLGTTLTILRDVILVLMEGTPKGVDFTTVKNLLLSVDGVEALHSLHIWALTVAQPVLSVHIAIAQNADAQAVLKVARDRLQGKFNFHTMTIQIEKYSEDMKNCQACQGPLE 291

[Close]

BLAST of slc30a-8 vs. Ensembl Mouse
Match: Slc30a3 (solute carrier family 30 (zinc transporter), member 3 [Source:MGI Symbol;Acc:MGI:1345280])

HSP 1 Score: 318.161 bits (814), Expect = 1.035e-105
Identity = 158/336 (47.02%), Postives = 229/336 (68.15%), Query Frame = 1

Query:  226 HCHG---PSEAIGVDK-NARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHG--HTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            HCH    P   +  ++  AR++L  A  +C IFM GE+VGG +A SLAIMTDAAHLL D  S + SLF+++L++RPAT+ M+FGWHR+E +GAL SV+ +W+VTGIL+YLA +R++  ++ IE G ML+T+   +  NL+MA  LHQ G  H+HGS+ +     +E GH +  S   N +VRAAF+HV+GDL+QS GV  A+++IY KP+YK+ADPI TF+FSI  L +T   LRD ++VLMEG P+ ++F  V+     +PGV   H+L +W+LT++    S H+AID   +   +L +AS+ L  RF  +  T+Q+E Y  EMA+C +CQ+P+ 
Sbjct:    5 HCHKDPVPQSGLSPERVQARRQLYAACAVCFIFMAGEVVGGYLAHSLAIMTDAAHLLADIGSMLASLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWIVTGILLYLAFLRLLHSDYHIEAGAMLLTASIAVCANLLMAFVLHQTGAPHSHGSTGAEYAPLEE-GHGYPMSLG-NTSVRAAFVHVLGDLLQSFGVLAASILIYFKPQYKVADPISTFLFSICALGSTAPTLRDVLLVLMEGAPRSVEFEPVRDTLLSVPGVRATHDLHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPSQ 338

[Close]

BLAST of slc30a-8 vs. Ensembl Mouse
Match: Slc30a3 (solute carrier family 30 (zinc transporter), member 3 [Source:MGI Symbol;Acc:MGI:1345280])

HSP 1 Score: 318.931 bits (816), Expect = 3.169e-105
Identity = 158/336 (47.02%), Postives = 228/336 (67.86%), Query Frame = 1

Query:  226 HCHG---PSEAIGVDK-NARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHG--HTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            HCH    P   +  ++  AR++L  A  +C IFM GE+VGG +A SLAIMTDAAHLL D  S + SLF+++L++RPAT+ M+FGWHR+E +GAL SV+ +W+VTGIL+YLA +R++  ++ IE G ML+T+   +  NL+MA  LHQ G  H+HGS+ +      E GH +  S   N +VRAAF+HV+GDL+QS GV  A+++IY KP+YK+ADPI TF+FSI  L +T   LRD ++VLMEG P+ ++F  V+     +PGV   H+L +W+LT++    S H+AID   +   +L +AS+ L  RF  +  T+Q+E Y  EMA+C +CQ+P+ 
Sbjct:   54 HCHKDPVPQSGLSPERVQARRQLYAACAVCFIFMAGEVVGGYLAHSLAIMTDAAHLLADIGSMLASLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWIVTGILLYLAFLRLLHSDYHIEAGAMLLTASIAVCANLLMAFVLHQTGAPHSHGSTGAEY-APLEEGHGYPMSLG-NTSVRAAFVHVLGDLLQSFGVLAASILIYFKPQYKVADPISTFLFSICALGSTAPTLRDVLLVLMEGAPRSVEFEPVRDTLLSVPGVRATHDLHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPSQ 387

[Close]

BLAST of slc30a-8 vs. UniProt/SwissProt
Match: sp|Q2HJ10|ZNT2_MOUSE (Zinc transporter 2 OS=Mus musculus OX=10090 GN=Slc30a2 PE=1 SV=1)

HSP 1 Score: 374.4 bits (960), Expect = 2.396e-126
Identity = 179/320 (55.94%), Postives = 241/320 (75.31%), Query Frame = 1

Query:  262 KNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--HGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            + AR+KL VAS +CL+FMIGEI+GG +A SLAIMTDAAHLLTDFAS +ISLFA++++SRPATK M+FGWHRAE++GAL+SVL IWVVTG+LVYLAV R++S +++I+G  MLITS   + +NLIM   LHQ  HGH+HG+S+ ++            S+++N +VRAAFIHVIGDL+QS+GV +AA +IY KP+YK  DPICTF+FSILVL TT+ ILRD ++VLMEGTPK +DF  VK     + GV  +H+L +W+LT+++  LSVHIAI  + +   +L+ A + L+ +F    +TIQ+E Y  +M  CQ CQ P +
Sbjct:   64 QRARRKLYVASAICLVFMIGEIIGGYLAQSLAIMTDAAHLLTDFASMLISLFALWVSSRPATKTMNFGWHRAEILGALLSVLSIWVVTGVLVYLAVQRLISGDYEIKGDTMLITSGCAVAVNLIMGLALHQSGHGHSHGNSRDDS------------SQQQNPSVRAAFIHVIGDLLQSVGVLVAAYIIYFKPEYKYVDPICTFLFSILVLGTTLTILRDVILVLMEGTPKGVDFTTVKNLLLSVDGVEALHSLHIWALTVAQPVLSVHIAIAQNADAQAVLKVARDRLQGKFNFHTMTIQIEKYSEDMKNCQACQGPLE 371

[Close]

BLAST of slc30a-8 vs. UniProt/SwissProt
Match: sp|Q62941|ZNT2_RAT (Zinc transporter 2 OS=Rattus norvegicus OX=10116 GN=Slc30a2 PE=2 SV=1)

HSP 1 Score: 355.525 bits (911), Expect = 3.599e-119
Identity = 176/335 (52.54%), Postives = 245/335 (73.13%), Query Frame = 1

Query:  226 HCHGPSEAIGVDKN-----ARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            +CH   ++ G   N     AR+KL VAS +CL+FMIGEI+GG +A SLAIMTDAAHLLTDFAS +ISLF+++++SRPATK M+FGW RAE++GAL+SVL IWVVTG+LVYLAV R++S +++I+G  MLITS   + +N+IM   LHQ GH H    S+ ++ +         +++N +VRAAFIHV+GDL+QS+GV +AA +IY KP+YK  DPICTF+FSILVL TT+ ILRD ++VLMEGTPK +DF  VK     + GV  +H+L +W+LT+++  LSVHIAI  + +   +L+ A + L+ +F    +TIQ+E+Y  +M  CQ+CQ P++
Sbjct:   35 YCHAQKDS-GSHPNSEKQRARRKLYVASAICLVFMIGEIIGGYLAQSLAIMTDAAHLLTDFASMLISLFSLWVSSRPATKTMNFGWQRAEILGALLSVLSIWVVTGVLVYLAVQRLISGDYEIKGDTMLITSGCAVAVNIIMGLALHQSGHGHSHGHSHEDSSQ---------QQQNPSVRAAFIHVVGDLLQSVGVLVAAYIIYFKPEYKYVDPICTFLFSILVLGTTLTILRDVILVLMEGTPKGVDFTTVKNLLLSVDGVEALHSLHIWALTVAQPVLSVHIAIAQNVDAQAVLKVARDRLQGKFNFHTMTIQIESYSEDMKSCQECQGPSE 359

[Close]

BLAST of slc30a-8 vs. UniProt/SwissProt
Match: sp|Q5XHB4|ZNT8_XENTR (Zinc transporter 8 OS=Xenopus tropicalis OX=8364 GN=slc30a8 PE=2 SV=1)

HSP 1 Score: 328.561 bits (841), Expect = 2.599e-108
Identity = 164/338 (48.52%), Postives = 231/338 (68.34%), Query Frame = 1

Query:  226 HCHGPSEAIGVDKN-----ARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--HGHTHGSSKSNNETDKEHGHSHGKSE---KENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDP 1209
            HCH  ++     +      A+KKL +AS++C +F+  EIVGG +A SLA++TDAAHLL D +SF ISL +++L+S+ +T R++FGWHRAE++GAL+SV+ IW+VTG+LVYLA  R++  ++ I+G +MLITS   +  NL++A  LHQ  HGH+H   K          H H  SE   + N ++RAAFIHVIGDL QSI V I+AL+IY KP+YK+ADPICTFIFSI VLITT+ +LRD + VLMEGTP+ + +++VK +   + GV  VH+L +W+LT+++  LS HIA D   E+  IL+D +  +  RF    VTIQ+E    +  EC  C +P
Sbjct:   45 HCHNNNKKAYDARQREQTFAKKKLCIASLICFVFISAEIVGGYIAGSLAVVTDAAHLLVDLSSFFISLCSLWLSSKSSTTRLTFGWHRAEILGALMSVITIWLVTGVLVYLACERLIRPDYTIDGTVMLITSACALGANLVLALILHQSGHGHSHAGGK----------HEHMASEYKPQTNASIRAAFIHVIGDLFQSISVLISALIIYFKPEYKMADPICTFIFSIFVLITTVTVLRDLLTVLMEGTPRGIHYSDVKQSILAVDGVKSVHSLHLWALTMNQVILSAHIATDIVGESKRILKDVTQNVFARFPFHSVTIQVEPIEDQSPECMFCYEP 372

[Close]

BLAST of slc30a-8 vs. UniProt/SwissProt
Match: sp|Q08E25|ZNT3_BOVIN (Zinc transporter 3 OS=Bos taurus OX=9913 GN=SLC30A3 PE=2 SV=1)

HSP 1 Score: 328.561 bits (841), Expect = 3.869e-108
Identity = 159/339 (46.90%), Postives = 225/339 (66.37%), Query Frame = 1

Query:  226 HCHG---PSEAIGVDK-NARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHG--HTHGSSKSNNETDKEHGHSHGKSEK---ENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            HCH    P   +  ++  A+++L  A  +C +FM GE+VGG +A SLAIMTDAAHLL D  S M SLF+++L++RPAT+ M+FGWHR+E +GAL SV+ +W+VTGIL+YLA +R++  ++ IEGG ML+T+   +  NL+MA  LHQ G  H+HGS  +     +E     G  E     N +VRAAF+HV+GDL+QS+GV IA+++IY KP+YK ADPI TF+FSI  L +T   LRD + VLMEGTP+ + F  V+     +PGV  +H L +WSLT +    S H+AID   +   +L +A++ L  RF  +  T+Q+E Y  EMA+C +CQ+P  
Sbjct:   54 HCHRDPLPQPGLTPERMQAQRQLCTACAVCCVFMAGEVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWMVTGILLYLAFIRLLHSDYHIEGGAMLLTASIAVCANLLMAFVLHQAGPPHSHGSRGAEYAPLEE-----GSGEPLPLGNTSVRAAFVHVLGDLLQSLGVLIASILIYFKPQYKAADPISTFLFSICALGSTAPTLRDVLRVLMEGTPRSVSFEPVRDTLLSVPGVRAIHELHLWSLTFTHYVASAHLAIDSTADPEAVLAEATSRLHSRFGFSSCTLQVEQYQPEMAQCLRCQEPPQ 387

[Close]

BLAST of slc30a-8 vs. UniProt/SwissProt
Match: sp|Q99726|ZNT3_HUMAN (Zinc transporter 3 OS=Homo sapiens OX=9606 GN=SLC30A3 PE=1 SV=2)

HSP 1 Score: 327.405 bits (838), Expect = 1.083e-107
Identity = 158/339 (46.61%), Postives = 225/339 (66.37%), Query Frame = 1

Query:  226 HCHG---PSEAIGVDK-NARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHG--HTHGSSKSNNETDKEHGHSHGKSEK---ENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            HCH    P   +  ++ +AR++L  A  +C +FM GE+VGG +A SLAIMTDAAHLL D  S M SLF+++L++RPAT+ M+FGWHR+E +GAL SV+ +W+VTGIL+YLA +R++  ++ IEGG ML+T+   +  NL+MA  LHQ G  H+HGS  +     +E     G  E     N +VRAAF+HV+GDL+QS GV  A+++IY KP+YK ADPI TF+FSI  L +T   LRD + +LMEGTP+++ F  V+     +PGV   H L +W+LT++    S H+AID   +   +L +AS+ L  RF  +  T+Q+E Y  EMA+C +CQ+P  
Sbjct:   54 HCHRDPLPPPGLTPERLHARRQLYAACAVCFVFMAGEVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWMVTGILLYLAFVRLLHSDYHIEGGAMLLTASIAVCANLLMAFVLHQAGPPHSHGSRGAEYAPLEE-----GPEEPLPLGNTSVRAAFVHVLGDLLQSFGVLAASILIYFKPQYKAADPISTFLFSICALGSTAPTLRDVLRILMEGTPRNVGFEPVRDTLLSVPGVRATHELHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPPQ 387

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BLAST of slc30a-8 vs. TrEMBL
Match: A0A0H3YKE4 (Slc30a-8 OS=Schmidtea mediterranea OX=79327 GN=slc30a-8 PE=2 SV=1)

HSP 1 Score: 791.956 bits (2044), Expect = 0.000e+0
Identity = 384/384 (100.00%), Postives = 384/384 (100.00%), Query Frame = 1

Query:   64 MAKEFVKRNIPSVVRGAIFHEHKEDQQVLIENDACINYYGSSTGITRTSSDFSDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            MAKEFVKRNIPSVVRGAIFHEHKEDQQVLIENDACINYYGSSTGITRTSSDFSDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD
Sbjct:    1 MAKEFVKRNIPSVVRGAIFHEHKEDQQVLIENDACINYYGSSTGITRTSSDFSDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 384

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BLAST of slc30a-8 vs. TrEMBL
Match: A0A504YFT6 (Zinc transporter OS=Fasciola gigantica OX=46835 GN=FGIG_05430 PE=4 SV=1)

HSP 1 Score: 460.299 bits (1183), Expect = 3.166e-157
Identity = 221/365 (60.55%), Postives = 284/365 (77.81%), Query Frame = 1

Query:  199 TRTSSDFSD----HCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATL---------------------HQHGHTHGSSKSNNETDKEHG---HSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDP 1209
            T +++++SD    HCH  + ++ VDK AR+KL++AS LCL+FMIGEIVGGA+A SLAIMTDAAHLLTDFASF+ISL A++LASRP+TK+MSFGWHRAEVVGAL SVLMIW+VTGILVYLAVMRV+   ++I+G IMLITSI G+ +N+IM  TL                     H HG +H  S SN   D EH     +  +++++NI VRAA IHVIGDLVQS+GVF+AA++I+ KP  K+ DPICTF+FSILVLITTINILRDT+ VLME TP+ L+FNEVK A  D+PGV+E+HNLRMWSLT++KTA+SVH+AID + ++  ILR AS++LR R+ + +VTIQ+E Y+ EMA+CQ+CQ+P
Sbjct:   36 TSSAAEYSDGARGHCHDSATSVSVDKQARRKLVLASGLCLVFMIGEIVGGALAQSLAIMTDAAHLLTDFASFLISLLALFLASRPSTKKMSFGWHRAEVVGALASVLMIWLVTGILVYLAVMRVIHQHYEIDGKIMLITSIIGVCVNIIMVLTLHDHGHGHSHGGGPSDRSPLKGHSHGGSHEHSHSNGAGDHEHKVDQRTQREAQRQNITVRAALIHVIGDLVQSLGVFVAAMIIFFKPSLKVVDPICTFVFSILVLITTINILRDTLNVLMEATPRGLEFNEVKNALNDIPGVVELHNLRMWSLTMNKTAVSVHLAIDREYDSQEILRQASSLLRMRYLVHEVTIQMEPYIPEMADCQRCQEP 400

[Close]

BLAST of slc30a-8 vs. TrEMBL
Match: A0A267DB27 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021642g1 PE=4 SV=1)

HSP 1 Score: 454.907 bits (1169), Expect = 2.041e-155
Identity = 223/358 (62.29%), Postives = 275/358 (76.82%), Query Frame = 1

Query:  172 NYYGSSTGITRTSSDFSDHCHGPSE------AIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGS----SKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            +Y+    G T + S+   HCH   +      A+G  + AR+KL VAS+LCL+FM GEIVGGA+A+SLAIMTDAAHLLTDFASFMISL A+YLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLA+ RVV+  F+++G  MLITS  G+ +N+IMA TLHQHGH+HG+    S +NN  + +HGHS      +NINVRAAFIHV+GD +QS+GV  AA VIY +P  K+ADPICTF+FSILVL TT +ILRDTM VLME TPK LDFN VK     +PGVIEVHNLR+WSLT++KTA+S H+A+  D     +L  A+ +++QRFQ+ +VT+Q+E YV  MA+C+ CQDP D
Sbjct:   31 SYHAMQRG-TSSDSEAGLHCHASEQVREQLLALG-QRTARRKLWVASLLCLLFMAGEIVGGAIANSLAIMTDAAHLLTDFASFMISLLALYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAIERVVNQNFEVQGQAMLITSGVGVAVNIIMAVTLHQHGHSHGTDHGHSHANNHGNDDHGHS-----DQNINVRAAFIHVVGDFLQSLGVLCAAFVIYYRPDLKLADPICTFLFSILVLFTTFSILRDTMRVLMEATPKGLDFNIVKETLASVPGVIEVHNLRLWSLTMNKTAVSAHLAVVKDANQQELLLAATRLVKQRFQLHEVTVQIEEYVEAMADCEHCQDPQD 381

[Close]

BLAST of slc30a-8 vs. TrEMBL
Match: A0A267DEN5 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031079g1 PE=4 SV=1)

HSP 1 Score: 454.136 bits (1167), Expect = 4.677e-155
Identity = 223/358 (62.29%), Postives = 274/358 (76.54%), Query Frame = 1

Query:  172 NYYGSSTGITRTSSDFSDHCHGPSE------AIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHT----HGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            +Y+    G T + S+   HCH   +      A+G  + AR+KL VAS+LCL+FM GEIVGGA+A+SLAIMTDAAHLLTDFASFMISL A+YLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLA+ RVV+  F+++G  MLITS  G+ +N+IMA TLHQHGH+    HG S +NN  + +HGHS      +NINVRAAFIHV+GD +QS+GV  AA VIY +P  K+ADPICTF+FSILVL TT +ILRDTM VLME TPK LDFN VK     +PGVIEVHNLR+WSLT++KTA+S H+A+  D     +L  A+ +++QRFQ+ +VT+Q+E YV  MA+C+ CQDP D
Sbjct:   31 SYHAMQRG-TSSDSEAGLHCHASEQVREQLLALG-QRTARRKLWVASLLCLLFMAGEIVGGAIANSLAIMTDAAHLLTDFASFMISLLALYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAIERVVNQNFEVQGQAMLITSGVGVAVNIIMAVTLHQHGHSLGTDHGHSHANNHGNDDHGHS-----DQNINVRAAFIHVVGDFLQSLGVLCAAFVIYYRPDLKLADPICTFLFSILVLFTTFSILRDTMRVLMEATPKGLDFNIVKETLASVPGVIEVHNLRLWSLTMNKTAVSAHLAVVKDANQQELLLAATRLVKQRFQLHEVTVQIEEYVEAMADCEHCQDPQD 381

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BLAST of slc30a-8 vs. TrEMBL
Match: A0A4E0RCI3 (Zinc transporter OS=Fasciola hepatica OX=6192 GN=D915_002750 PE=4 SV=1)

HSP 1 Score: 454.521 bits (1168), Expect = 6.703e-155
Identity = 219/365 (60.00%), Postives = 283/365 (77.53%), Query Frame = 1

Query:  205 TSSDFSD----HCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATL-----------------------HQHGHTHGSSKSNNETDKEHG---HSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDP 1209
            +++++SD    HCH  + ++ VDK AR+KL++AS LCL+FMIGEIVGGA+A SLAIMTDAAHLLTDFASF+ISL A++LASRP+TK+MSFGWHRAEVVGAL SVLMIW+VTGILVYLAVMRV+   ++I+G IMLITSI G+ +N+IM  TL                       H HG +H  S S+   D EH     +  +++++NI VRAA IHVIGDLVQS+GVF+AA++I+ KP  K+ DPICTF+FSILVLITTINILRDT+ VLME TP+ L+FNEVK A  D+PGV+E+HNLRMWSLT++KTA+SVH+AID + ++  ILR AS++LR R+ + +VTIQ+E Y+ EMA+CQ+CQ+P
Sbjct:   41 SAAEYSDGVRGHCHDSATSVSVDKQARRKLVLASGLCLVFMIGEIVGGALAQSLAIMTDAAHLLTDFASFLISLLALFLASRPSTKKMSFGWHRAEVVGALASVLMIWLVTGILVYLAVMRVIHQHYEIDGKIMLITSIIGVCVNIIMVLTLHDHGHGHGHSHGGGPSDRSPLTGHSHGGSHEHSHSDGAGDHEHKVDQRTQREAQRQNITVRAALIHVIGDLVQSLGVFVAAMIIFFKPSLKVVDPICTFVFSILVLITTINILRDTLNVLMEATPRGLEFNEVKNALNDIPGVVELHNLRMWSLTMNKTAVSVHLAIDREYDSQEILRQASSLLRMRYLVHEVTIQMEPYIPEMADCQRCQEP 405

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BLAST of slc30a-8 vs. Ensembl Cavefish
Match: slc30a2 (zinc transporter 2 [Source:NCBI gene;Acc:103036936])

HSP 1 Score: 372.089 bits (954), Expect = 4.299e-126
Identity = 175/355 (49.30%), Postives = 249/355 (70.14%), Query Frame = 1

Query:  181 GSSTGITRTSSDFSDHCHGPSEAIGVDKN---ARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ----HGHTHGSSK--SNNETDKEHGHSHGK-SEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            G + G          HCHG   A   ++    A+KKL +ASI+CL+FMIGE++GG +A SLAIMTDAAHLLTDF S M+SLF+++++SRP TK M+FG+HR+E++GA +SV+ IW+VTG+LVYLA+ R+V  +++IEG +ML+TS   +++N+IMA  LH     HGH  G  K   N  +   HGHSH   S   N +VRAAFIHV+GDL+QS GV +AA++IY +P+YK+ADPICTF+FS+ VL TTI ILRD   +LMEG P+ ++FN VK     L  V  +H+L +W+LT+ ++ +SVH+AI+ + +  ++L++A+ +L+ +F     TIQ+E Y  +MA C  CQDP D
Sbjct:   44 GDTAGAIELKRPTGTHCHGKKTAWEENREKLVAKKKLYIASIVCLVFMIGEVIGGYLAHSLAIMTDAAHLLTDFGSMMVSLFSLWISSRPPTKTMNFGFHRSEILGAFISVMSIWIVTGVLVYLAIERIVKNDYEIEGHVMLLTSGCAVVVNIIMAYILHHSTTFHGHGSGYHKIDENGMSPVGHGHSHSLLSGHGNTSVRAAFIHVLGDLLQSFGVLVAAIIIYFRPEYKVADPICTFLFSVFVLGTTITILRDVFRILMEGAPRGIEFNSVKEVLLSLKAVKAIHSLHLWALTVGQSLVSVHVAIEENADHQSVLKEATELLQTKFGFYSTTIQIEPYCEDMAYCTLCQDPVD 398

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BLAST of slc30a-8 vs. Ensembl Cavefish
Match: slc30a8 (solute carrier family 30 member 8 [Source:ZFIN;Acc:ZDB-GENE-060315-10])

HSP 1 Score: 363.999 bits (933), Expect = 6.510e-123
Identity = 186/395 (47.09%), Postives = 262/395 (66.33%), Query Frame = 1

Query:  133 EDQQVLIENDACINYYGSSTGITRTSSDF----SDHCHGPSEAI----GVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--HGHTHG--SSKSNNET-------DKEHGHSH---------------GKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            + ++ L+  D   N Y + T  + +S D     S HCH  S A        K ARK+L + S++CL+FM+GEI+GG  A SLA+MTDAAHLL DF SF+ISL +++L+SRPAT  +++GWHRAE++GAL+SV  IW+VTG+LVYLAV R++S +++IEG +MLITS   ++ N+IMA TLHQ  HGH+HG  SS+ +  +       +K++GHSH               GK  +EN +VRAAF+HVIGDL+QSI V ++AL+I+ +P+YK+ADPICTF+FS+ VL TT  I+RD +VVLMEGTP  +D+ EV+     + GV  VHNL +W+LT+++  LS H+AID   E   +LR+ +      +    VTIQLE    +  +C  CQDP +
Sbjct:    5 DPEKALLVKDKAANMY-TITMESVSSGDMVLKDSKHCHDSSHAFEDREKEKKVARKRLYIVSVVCLVFMVGEILGGYFAGSLAVMTDAAHLLVDFTSFIISLCSLWLSSRPATHTLNYGWHRAEILGALLSVFTIWLVTGVLVYLAVERLISDDYEIEGTVMLITSGCAVLANIIMALTLHQSGHGHSHGGLSSQGHGHSHSGAHSHEKKNGHSHAYANGDSHNPENKTTGKKTQENASVRAAFVHVIGDLLQSISVLVSALIIFFRPEYKMADPICTFLFSLFVLGTTFTIMRDILVVLMEGTPAGVDYREVRERLLSVKGVKAVHNLHIWALTMNQAVLSAHVAIDDATEPQVVLREITQSCFTTYSFHSVTIQLEQQEDQRPDCTLCQDPKN 398

[Close]

BLAST of slc30a-8 vs. Ensembl Cavefish
Match: SLC30A2 (zinc transporter 2-like [Source:NCBI gene;Acc:103045971])

HSP 1 Score: 334.724 bits (857), Expect = 7.570e-112
Identity = 161/333 (48.35%), Postives = 227/333 (68.17%), Query Frame = 1

Query:  226 HCHGPSEAIGVDKN---ARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            HCH    A   ++    A +KLL+ SILCL+FMIGE++GG  A SLA+MTDAAHLLTDF S +ISLF+++++SRPA+K M++GWHR+EV+G L+SVL IW VT +LV++A+ R++  +++I  G MLITS   +I+N++MA  LHQ                   H        N +VRAAFIHV+GDL+QS+GV +AA +IY  P++KIADP+CTF+FSIL+L TT  IL+D   +LMEGTP  +DF+ VK A   + GV  +H+L +W+LT+S+  +SVH  ID      T+L D + ML+  F   ++TIQ+E Y ++ A C++CQDP D
Sbjct:   48 HCHNSRAAWAQNEEKSGAWRKLLITSILCLVFMIGEVIGGYAAHSLAVMTDAAHLLTDFGSILISLFSLWISSRPASKTMTYGWHRSEVLGGLLSVLSIWAVTAVLVFIAIQRILQNDYEIHSGAMLITSGCAVIVNILMALILHQ----------------SPAHHGHSHGHSNTSVRAAFIHVVGDLLQSLGVALAATIIYFWPEWKIADPVCTFLFSILILATTSTILKDIFKILMEGTPHGIDFDFVKEALLAVRGVKSIHSLHLWALTMSQPQISVHTVIDEQTSPQTVLLDLTEMLQSDFNFHNITIQIETYSNDAAHCRECQDPID 364

[Close]

BLAST of slc30a-8 vs. Ensembl Cavefish
Match: SLC30A2 (zinc transporter 2-like [Source:NCBI gene;Acc:103045971])

HSP 1 Score: 333.954 bits (855), Expect = 9.990e-112
Identity = 161/333 (48.35%), Postives = 227/333 (68.17%), Query Frame = 1

Query:  226 HCHGPSEAIGVDK---NARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            HCH    A   ++    A +KLL+ SILCL+FMIGE++GG  A SLA+MTDAAHLLTDF S +ISLF+++++SRPA+K M++GWHR+EV+G L+SVL IW VT +LV++A+ R++  +++I  G MLITS   +I+N++MA  LHQ                   H        N +VRAAFIHV+GDL+QS+GV +AA +IY  P++KIADP+CTF+FSIL+L TT  IL+D   +LMEGTP  +DF+ VK A   + GV  +H+L +W+LT+S+  +SVH  ID      T+L D + ML+  F   ++TIQ+E Y ++ A C++CQDP D
Sbjct:   35 HCHNSRAAWAQNEEKSGAWRKLLITSILCLVFMIGEVIGGYAAHSLAVMTDAAHLLTDFGSILISLFSLWISSRPASKTMTYGWHRSEVLGGLLSVLSIWAVTAVLVFIAIQRILQNDYEIHSGAMLITSGCAVIVNILMALILHQ----------------SPAHHGHSHGHSNTSVRAAFIHVVGDLLQSLGVALAATIIYFWPEWKIADPVCTFLFSILILATTSTILKDIFKILMEGTPHGIDFDFVKEALLAVRGVKSIHSLHLWALTMSQPQISVHTVIDEQTSPQTVLLDLTEMLQSDFNFHNITIQIETYSNDAAHCRECQDPID 351

[Close]

BLAST of slc30a-8 vs. Ensembl Cavefish
Match: slc30a8 (solute carrier family 30 member 8 [Source:ZFIN;Acc:ZDB-GENE-060315-10])

HSP 1 Score: 327.405 bits (838), Expect = 2.972e-109
Identity = 168/369 (45.53%), Postives = 238/369 (64.50%), Query Frame = 1

Query:  133 EDQQVLIENDACINYYGSSTGITRTSSDF----SDHCHGPSEAI----GVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            + ++ L+  D   N Y + T  + +S D     S HCH  S A        K ARK+L + S++CL+FM+GEI+GG  A SLA+MTDAAHLL DF SF+ISL +++L+SRPAT  +++GWHRAE++GAL+SV  IW+VTG+LVYLAV R++S +++IEG +MLITS   ++ N+IMA TLHQ                        S   + +  +AF+HVIGDL+QSI V ++AL+I+ +P+YK+ADPICTF+FS+ VL TT  I+RD +VVLMEGTP  +D+ EV+     + GV  VHNL +W+LT+++  LS H+AID   E   +LR+ +      +    VTIQLE    +  +C  CQDP +
Sbjct:    5 DPEKALLVKDKAANMY-TITMESVSSGDMVLKDSKHCHDSSHAFEDREKEKKVARKRLYIVSVVCLVFMVGEILGGYFAGSLAVMTDAAHLLVDFTSFIISLCSLWLSSRPATHTLNYGWHRAEILGALLSVFTIWLVTGVLVYLAVERLISDDYEIEGTVMLITSGCAVLANIIMALTLHQ------------------------SGHGHGHSHSAFVHVIGDLLQSISVLVSALIIFFRPEYKMADPICTFLFSLFVLGTTFTIMRDILVVLMEGTPAGVDYREVRERLLSVKGVKAVHNLHIWALTMNQAVLSAHVAIDDATEPQVVLREITQSCFTTYSFHSVTIQLEQQEDQRPDCTLCQDPKN 348

[Close]

BLAST of slc30a-8 vs. Ensembl Sea Lamprey
Match: slc30a2 (solute carrier family 30 member 2 [Source:ZFIN;Acc:ZDB-GENE-041014-347])

HSP 1 Score: 347.436 bits (890), Expect = 3.558e-117
Identity = 166/325 (51.08%), Postives = 236/325 (72.62%), Query Frame = 1

Query:  253 GVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHR-AEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--HGHTHGSSKSNNETDKEHGHSHGK--SEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPA 1212
            G  ++AR+KL +A+++CL+FM GEI GG +A SLAIMTDAAHL  DFASF ISLF+++++SRP TK M+FGW+R  E++GAL+SVL IWVVTG+LVYLA +R++  +F+IEG  ML+TS   I +N+IM+ TL+Q  H H+HG   ++    K    + G     + N +VRAAFIHV+GDL+QSIGV IAA VIY +P+YKIADPICTF+FS  VL TT+ ILRD ++VLMEG P+ + F +V+ A   LP V  VH++ +WSLTI+  A+  H+ +D   +   ++R+A+ +L+ RF  + +TIQ+E +  +M  C+ CQ+P+
Sbjct:   64 GERRHARRKLCIAAVICLLFMAGEIFGGFLAHSLAIMTDAAHLFADFASFSISLFSLWVSSRPPTKTMNFGWYRMPEILGALLSVLTIWVVTGVLVYLASLRLIYKDFEIEGTAMLVTSGCAIAVNVIMSFTLYQANHLHSHGGVTADATEPKPLTMAEGPVSGPQANPSVRAAFIHVVGDLLQSIGVLIAACVIYAEPEYKIADPICTFVFSFFVLFTTVTILRDVLLVLMEGAPRAVKFTDVQEALLALPHVCSVHDVHLWSLTINHCAICAHVCVDDIGKGEEVVREATVVLQTRFSFSVLTIQVEKFTEDMHSCRDCQEPS 388

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BLAST of slc30a-8 vs. Ensembl Sea Lamprey
Match: slc30a2 (solute carrier family 30 member 2 [Source:ZFIN;Acc:ZDB-GENE-041014-347])

HSP 1 Score: 201.83 bits (512), Expect = 3.791e-63
Identity = 102/189 (53.97%), Postives = 135/189 (71.43%), Query Frame = 1

Query:  265 NARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLK 831
             A+++L + S++C +F+IGE VGG +A SLAIMTD AHLLTDFASF ISL +++LA RP +KRM+FGW+RAE++GAL+S+  IWVVTG+LVYLA  R++S +F IEG  ML TS   +I+N IM   LH   H              HGHSH +S   N ++RAAFIH +GDL+QSIGV +AA +I+ K
Sbjct:    1 RAKRQLYLVSVICFVFIIGEAVGGILAHSLAIMTDVAHLLTDFASFSISLLSLWLADRPTSKRMTFGWYRAEILGALLSIFSIWVVTGVLVYLAACRMISRDFAIEGTAMLATSACAVIVN-IMCVRLHTVSH--------------HGHSHLQSH-SNPSIRAAFIHALGDLLQSIGVLVAACIIFFK 173

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BLAST of slc30a-8 vs. Ensembl Sea Lamprey
Match: slc30a2 (solute carrier family 30 member 2 [Source:ZFIN;Acc:ZDB-GENE-041014-347])

HSP 1 Score: 182.57 bits (462), Expect = 3.600e-56
Identity = 89/168 (52.98%), Postives = 119/168 (70.83%), Query Frame = 1

Query:  361 MTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKE----HGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIAD 852
            MTD AHLLTDFASF ISL +++LA RP +KRM+FGW+RAE++GAL+S+  IWVVTG+LVYLA  R++S +F IEG  ML TS   +I+N+IMA  L +  H+ G S  +          HGHSH +S   N ++RAAFIH +GDL+QSIGV +AA +I+ KP   + +
Sbjct:    1 MTDVAHLLTDFASFSISLLSLWLADRPTSKRMTFGWYRAEILGALLSIFSIWVVTGVLVYLAACRMISRDFAIEGTAMLATSACAVIVNIIMAVLLARGHHSSGPSGDSEAPPAVPLHLHGHSHLQSH-SNPSIRAAFIHALGDLLQSIGVLVAACIIFFKPPLPMPE 167

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BLAST of slc30a-8 vs. Ensembl Sea Lamprey
Match: slc30a10 (solute carrier family 30 member 10 [Source:ZFIN;Acc:ZDB-GENE-060608-2])

HSP 1 Score: 110.923 bits (276), Expect = 7.915e-28
Identity = 74/279 (26.52%), Postives = 138/279 (49.46%), Query Frame = 1

Query:  295 ILCL--IFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGG-IMLITSIAGIIINLI----------MAATLHQHGHTHGSSKSNNET-DKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYK--------IADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHI 1065
            +LC   +F + E+V G + +SLA++ D+ ++L+D  S    L +  LA  PAT R ++G  R EVV AL +   + V   + V +  ++ +S    I+   ++LI    G+ +NL            +    +     G+      T D+E G S  +S++  IN+R   +H +GD + S+ V I A++  ++P             DP  T   +++++ + + ++R+  V+L++  P D+   +++     +PGV  +H L +W LT  +   SVHI
Sbjct:   14 MLCFTSVFFVTELVSGYVGNSLALVADSFNMLSDALSLTSGLASARLARWPATSRHTYGLVRGEVVSALATASFL-VALSLSVAVQALKALSQPDVIDNPRLVLIVGALGLSVNLTGLMLFQDCFSCSRLCARFNAAEGTDDRKPRTGDEEMGASVKRSKENAINIRGVLLHTLGDALGSVTVVITAIIFNVRPIASKEECNWQCYIDPALTIAMTLIIITSAVRLIREAAVILLQIVPPDILIKDIEQKLSGIPGVQSIHRLHVWRLTAGRDVASVHI 291

[Close]

BLAST of slc30a-8 vs. Ensembl Sea Lamprey
Match: slc30a10 (solute carrier family 30 member 10 [Source:ZFIN;Acc:ZDB-GENE-060608-2])

HSP 1 Score: 98.9821 bits (245), Expect = 4.138e-23
Identity = 86/351 (24.50%), Postives = 157/351 (44.73%), Query Frame = 1

Query:  295 ILCL--IFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGG-IMLITSIAGIIINLI-------------MAATLH----------QHGHTHGSSKSNNETD---------------------------KEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKP---KYKIA-----DPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLE 1164
            +LC   +F + E+V G + +SLA++ D+ ++L+D  S    L +  LA  PAT R ++G  R EVV AL +   + V   + V +  ++ +S    I+   ++LI    G+ +NL              + A  +          + G     S+  N TD                           +E G S  +S++  IN+R   +H +GD + S+ V I A++  ++P   K +       DP  T   +++++ + + ++R+  V+L++  P D+   +++     +PGV  +H L +W LT  +   SVHI      +  T      ++L Q   I D+T+Q E
Sbjct:   14 MLCFTSVFFVTELVSGYVGNSLALVADSFNMLSDALSLTSGLASARLARWPATSRHTYGLVRGEVVSALATASFL-VALSLSVAVQALKALSQPDVIDNPRLVLIVGALGLSVNLTGLMLFQDCFSCSRLCARFNAAEGTDDRKPRTGDKSTLSEKENYTDVSMKREDTFHFTYFIQPEERLIFTSGDEEMGASVKRSKENAINIRGVLLHTLGDALGSVTVVITAIIFNVRPIASKEECNWQCYIDPALTIAMTLIIITSAVRLIREAAVILLQIVPPDILIKDIEQKLSGIPGVQSIHRLHVWRLTAGRDVASVHIKCAGMSDYATAGLHIHDLL-QLEGIDDITVQPE 362

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BLAST of slc30a-8 vs. Ensembl Yeast
Match: ZRC1 (Vacuolar membrane zinc transporter; transports zinc from cytosol to vacuole for storage; also has role in resistance to zinc shock resulting from sudden influx of zinc into cytoplasm; human ortholog SLC30A10 functions as a Mn transporter and mutations in SLC30A10 cause neurotoxic accumulation of Mn in liver and brain; ZRC1 has a paralog, COT1, that arose from the whole genome duplication [Source:SGD;Acc:S000004856])

HSP 1 Score: 112.464 bits (280), Expect = 1.237e-27
Identity = 96/373 (25.74%), Postives = 174/373 (46.65%), Query Frame = 1

Query:  274 KKLLVASILCL--IFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLA-SRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHG------HTHGSSKSNN-----ETDKEHGHSHGKSEKENINVRAAFIHVIGD-------LVQSI----------------------------------GVF-------------IAALVIYLKPKYK---IADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAID--PDQETHTILRDASNMLRQRFQ---IADVTIQLE 1164
            K+L + S+L L  +F + EI  G M+ SLA++ D+ H+L D  S +++L+A+ +A +R    + ++GW RAE++GAL++ + +  +   ++  A+ R++  +      ++L   +AG+I N++     H HG      H+HGS +S N     E++  H HSH     +N+ +    I   G        L QS+                                  GVF             IAA +   K +Y     +DPI + I +I++  + + + R    +L++ TP  +  ++++     +PGVI VH+  +W+LT S    S+H+ ID  PD+        ++ ++R+ F    I   T+Q E
Sbjct:    5 KELRIISLLTLDTVFFLLEITIGYMSHSLALIADSFHMLNDIISLLVALWAVDVAKNRGPDAKYTYGWKRAEILGALINAVFLIALCFSIMIEALQRLIEPQEIQNPRLVLYVGVAGLISNVVGLFLFHDHGSDSLHSHSHGSVESGNNDLDIESNATHSHSHASLPNDNLAIDEDAISSPGPSGQIGEVLPQSVVNRLSNESQPLLNHDDHDHSHESKKPGHRSLNMHGVFLHVLGDALGNIGVIAAALFIWKTEYSWRYYSDPIVSLIITIIIFSSALPLSRRASRILLQATPSTISADQIQREILAVPGVIAVHDFHVWNLTESIYIASIHVQIDCAPDK-----FMSSAKLIRKIFHQHGIHSATVQPE 372

[Close]

BLAST of slc30a-8 vs. Ensembl Yeast
Match: COT1 (Vacuolar transporter that mediates zinc transport into the vacuole; overexpression confers resistance to cobalt and rhodium; protein abundance increases in response to DNA replication stress; COT1 has a paralog, ZRC1, that arose from the whole genome duplication [Source:SGD;Acc:S000005843])

HSP 1 Score: 77.7962 bits (190), Expect = 5.676e-16
Identity = 46/166 (27.71%), Postives = 83/166 (50.00%), Query Frame = 1

Query:  718 HGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYK---IADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQD 1206
            H K  K ++N+   F+HV+GD + +IGV ++A  I+ K  Y      DP+ + I + ++  + + +      +L++ TP  L  ++V+     +PG+I +H+  +W+LT S    S+HI +D   E  T L         R+ I   T+Q E    E+   ++  D
Sbjct:  232 HNK-RKRSLNMHGVFLHVLGDALGNIGVMLSAFFIW-KTDYSWKYYTDPLVSLIITGIIFSSALPLSCKASKILLQATPSTLSGDQVEGDLLKIPGIIAIHDFHIWNLTESIFIASLHIQLDISPEQFTDLAKIVRSKLHRYGIHSATLQPEFITREVTSTERAGD 395

HSP 2 Score: 63.1586 bits (152), Expect = 3.059e-11
Identity = 41/136 (30.15%), Postives = 77/136 (56.62%), Query Frame = 1

Query:  262 KNARKKLLVASILCL--IFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLA-SRPATKRMSFGWHRAEVVGALV-SVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQH 657
            K   K++ + S+L L  +F   EI  G ++ SLA++ D+ H+L D  S +++L+A+ +A +R      ++GW RAE++GAL+ +V +I +   IL+  A+ R+++         +L   +AG+I N +     H +
Sbjct:    2 KLGSKQVKIISLLLLDTVFFGIEITTGYLSHSLALIADSFHMLNDIISLVVALWAVNVAKNRNPDSTYTYGWKRAEILGALINAVFLIALCVSILIE-ALQRIIAPPVIENPKFVLYVGVAGLISNTVGLFLFHDN 136

[Close]

BLAST of slc30a-8 vs. Ensembl Yeast
Match: MSC2 (Endoplasmic reticulum zinc transporter; part of a heterodimeric transporter with Zrg17p that transfers zinc from the cytosol to the ER lumen; member of the cation diffusion facilitator family of efflux pumps; localizes to ER and nucleus; mutations affect the cellular distribution of zinc and also confer defects in meiotic recombination between homologous chromatids [Source:SGD;Acc:S000002613])

HSP 1 Score: 57.3806 bits (137), Expect = 2.396e-9
Identity = 51/210 (24.29%), Postives = 102/210 (48.57%), Query Frame = 1

Query:  244 EAIGVDKNARKKLLVASILCL--IFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGW-HRAEVVGALVSVLMIWVVTGILVYLAVMRVVS-MEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPIC 861
            + + ++K+ R    + S L L   FM  +++    + SL +++D+ H+  D  S ++ L A  L  +PA+ +  FG  +   + G    VL++ +V GI V  A+ R+ + +       ++++ ++  ++  + + A    HG                 H HG ++ EN+  +  F+H++ D + S+GV I+ L+I L   + I DPI 
Sbjct:  377 KQMALNKDTRS---IFSFLLLNTAFMFVQLLYSFRSKSLGLLSDSLHMALDCTSLLLGLIAGVLTKKPASDKFPFGLNYLGTLAGFTNGVLLLGIVCGIFVE-AIERIFNPIHLHATNELLVVATLGLLVNLVGLFA--FDHG----------------AHDHGGTDNENM--KGIFLHILADTLGSVGVVISTLLIKLT-HWPIFDPIA 561

[Close]

BLAST of slc30a-8 vs. Ensembl Yeast
Match: MMT2 (Putative metal transporter involved in mitochondrial iron accumulation; MMT2 has a paralog, MMT1, that arose from the whole genome duplication [Source:SGD;Acc:S000006145])

HSP 1 Score: 51.2174 bits (121), Expect = 2.058e-7
Identity = 26/72 (36.11%), Postives = 42/72 (58.33%), Query Frame = 1

Query:  316 IGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGI 531
            +G+ VGG    S A++ D+ H L+D  S  ++LF++  ASR  T    +G+ + E VG+L +V  I  + GI
Sbjct:  145 VGKFVGGITFHSQALLADSVHALSDLVSDFLTLFSVQYASRKPTSEYPYGYGKVETVGSL-AVSTILAMAGI 215

[Close]

BLAST of slc30a-8 vs. Ensembl Nematostella
Match: EDO30554 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0G7])

HSP 1 Score: 361.688 bits (927), Expect = 9.971e-124
Identity = 173/318 (54.40%), Postives = 236/318 (74.21%), Query Frame = 1

Query:  265 NARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLE-NYVSEMAECQQCQDPAD 1215
            N  ++L +AS LCL FMI E VGG  ++SLAIMTDAAH+L+DFA FMISLFAI++A+RPATK +S+GW+RAEV+GA++SVL+IWV+TG+LVY+A+ R++  E++++  +MLIT+  G++IN+IM A L+Q G               HGHSHG+ E+EN+NVRAAFIHVIGD +QS+GVF+AAL+I+ KP++ IADPICTFIFSI+VL TT+ IL+D ++VLMEG PK L FN++K +   +PGV  VH+L +WSLT+   ALSVH+ +D    T  IL  AS +  + F I   TIQ+E +  S    C++C DP D
Sbjct:    7 NPTRRLRIASFLCLFFMIAEFVGGYFSNSLAIMTDAAHMLSDFAGFMISLFAIWVATRPATKTLSYGWYRAEVMGAVLSVLVIWVLTGVLVYMALQRLIMKEYEVDAKVMLITASGGLLINVIMGAILYQKG---------------HGHSHGE-EEENVNVRAAFIHVIGDFLQSLGVFVAALIIWFKPEWAIADPICTFIFSIIVLFTTLAILKDALIVLMEGMPKGLSFNDLKTSLTAIPGVEAVHDLHVWSLTVGTDALSVHLVVDNSANTQDILEAASQVCSKSFDIHHSTIQIETDNGSRKESCKKCDDPQD 308

[Close]

BLAST of slc30a-8 vs. Ensembl Nematostella
Match: EDO43612 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY04])

HSP 1 Score: 337.806 bits (865), Expect = 4.619e-114
Identity = 181/327 (55.35%), Postives = 239/327 (73.09%), Query Frame = 1

Query:  271 RKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGH----SHGKS------EKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEG-TPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYV-SEMAECQQCQDPAD 1215
            RKKL  AS++CL F++ E+VGG +A SLAIMTDAAH+L+DFA+FMISLFAI++A     K+ +FG++RAE++GALVSVL+IWV+TGILVYLAV RV++ +F I   IMLIT+   + IN+++   LHQ G  HG S      D    H    SHGK       EKENINVRAAFIHV+GD+VQS+GV IAA +I  KP +K+ADPICTF+FSILVLITT+NI+RDT+ VLMEG TPK++++N VKA   ++ GV+  H+L +WSLT++K AL+VH+AI P+ ++  +L  A   L+ +FQI   TIQ+E Y  S M  C +CQD  D
Sbjct:    4 RKKLTTASVVCLFFVVAEVVGGYLAHSLAIMTDAAHMLSDFAAFMISLFAIWVAEWQPDKKRTFGYYRAEILGALVSVLIIWVLTGILVYLAVQRVITKDFDINADIMLITAGVALGINILLGIILHQSGVGHGHSHGGGGHDHGGSHSHSASHGKPRSGSVLEKENINVRAAFIHVLGDVVQSVGVLIAAYIIKYKPSWKLADPICTFLFSILVLITTLNIVRDTIHVLMEGSTPKNVNYNAVKAGLENIQGVVAAHSLHIWSLTVNKAALAVHLAIGPNVDSQKVLNIAHQKLKTQFQIFHSTIQVELYQESVMQSCTECQDLKD 330

[Close]

BLAST of slc30a-8 vs. Ensembl Nematostella
Match: EDO48857 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHI7])

HSP 1 Score: 212.231 bits (539), Expect = 1.315e-65
Identity = 106/305 (34.75%), Postives = 191/305 (62.62%), Query Frame = 1

Query:  274 KKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEF-----KIEGGIMLITSIAGIIINLIMAATLH---QHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLE 1164
            ++L++A++ C++F+  E+ GG +A+SLA+M DA H L D  S + SL A ++A      + ++G+ RAE++GA + +LM+W++TG+LVY A++R+++         +   +M+IT+      N+++A  L    +H H+HGS + N+  +             NIN+RAAF+H IGD++ + GV +A L+I +KP+++ AD IC+ + +++VL+TT  ++RD+  +L EG P+D+   EVK     L  V+  HN+ +W+LT  +  L+ H+ ++P+ +T T+L+ AS  L  ++ +   T+QLE
Sbjct:    1 RRLIIATLFCVVFIACEVTGGVIANSLAVMNDALHQLFDLNSLLASLLAAWIAGWKPNSQKTYGYFRAEILGACLVILMLWLLTGVLVYEALLRLLAGTAMGHSDHVNADVMMITAGFTCAANIVLAFMLSGVGRHHHSHGSYEKNDNCEG------------NINIRAAFLHTIGDIIYAFGVLLAGLIIKIKPEWQKADAICSLVGAVIVLVTTYAVIRDSFNILFEGVPRDVRIAEVKRDLSTLHHVVSFHNVHVWALTSGRNLLTAHLVVEPEADTQTLLKIASKRLSSKYSLYHCTLQLE 293

[Close]

BLAST of slc30a-8 vs. Ensembl Nematostella
Match: EDO34617 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNW3])

HSP 1 Score: 85.8853 bits (211), Expect = 7.243e-18
Identity = 67/341 (19.65%), Postives = 155/341 (45.45%), Query Frame = 1

Query:  256 VDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLI-----------------------------------MAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKA--AFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLEN 1167
            ++++  +++     L L+F   E++ G   +SL +++D  H+L D  + ++ L A  ++   A++  S+G+ R E++   V+ + + VV    V+LA ++ +    K+    +L  S+ G+++NL+                                      +   H  TH     N +    H H               F+HV+ D + S+GV IA+ ++  +    IADP+C+   + L+ ++ + +L+++ +VL++ TP D++ +   A        GV+   +   W  + S    ++H+ + P      I++  +++ ++ + + ++++Q+E 
Sbjct:  375 LEESESRQIFYFLCLNLMFTGVELLYGVWTNSLGLISDGFHMLFDCTALVLGLCASLMSRWKASRTFSYGFGRVEILSGFVNGIFL-VVIAFFVFLAAVQRLFDPPKVSTERLLAVSVGGLLVNLVGILAFRHAHAHAHGGGGSCGGGGGSHGHGHSHTHGHGHSHDHHPSTHPDRSVNMQGMYSHAH-------------GVFLHVVADTLGSVGV-IASSILIDQFGLFIADPVCSLFIASLIFLSVLPLLKESSLVLLQRTPLDMEKSLTGALNKILSFDGVLSFRDHHFWQHSESVVCGTIHVQVAPSASEQKIIQQVTSLFKE-YGVNNLSVQVEK 699

[Close]

BLAST of slc30a-8 vs. Ensembl Nematostella
Match: EDO29786 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2N0])

HSP 1 Score: 48.521 bits (114), Expect = 5.765e-7
Identity = 32/118 (27.12%), Postives = 59/118 (50.00%), Query Frame = 1

Query:  322 EIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLH--QHGHTH 669
            E+  G   +SL ++TD+ H+  D  + +  L A  +A     +R S+G+ RAE++   V+ L +  V   +   AV RV     +++   + + S+ G ++NL+     H  Q G +H
Sbjct:   27 ELAYGIWTNSLGLITDSFHMFFDCTALLAGLVASVIAHWGRNERFSYGYARAEIMAGFVNGLFLIFVAFFIFSEAVERVFHPP-EVKHERLFVVSVLGFLVNLVGIFVFHHGQGGKSH 143

[Close]

BLAST of slc30a-8 vs. Ensembl Medaka
Match: slc30a2 (solute carrier family 30 member 3 [Source:NCBI gene;Acc:101167260])

HSP 1 Score: 359.762 bits (922), Expect = 7.164e-122
Identity = 174/356 (48.88%), Postives = 246/356 (69.10%), Query Frame = 1

Query:  190 TGITRTSSDFSDHCHGPSEAIGVDKN----ARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMA------ATLHQHGHTHGSSKSNNETDKEHGHSH----GKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            +G        S HCH      G        A++KL +AS +CLIFMIGE++GG +A SLAIMTDAAHLLTDF S M+SLF+++++SRP TK M+FGWHR+E++GA VSV+ IWVVTG LVYLA+ R+V  +++IEG +ML TS   +I+N+IMA       TLH HG  +     +  +   HGH+H    G S   N +VRAAFIHVIGDL+QSIGV +AA++IY++P+YK+ADPICTF+FS+ VL TT+ ILRD   +LMEG+PK ++F+ VK     +  V  +H L +W+LT+ ++ +SVH+AI+ + +   IL++A+++L  +F    +TIQ+E Y  +M+ C  CQDP+D
Sbjct:    2 SGAMELKQRVSAHCHRSKPPHGEQSGDKVLAKRKLFIASGVCLIFMIGEVIGGYLAHSLAIMTDAAHLLTDFGSMMVSLFSLWISSRPPTKTMNFGWHRSEILGAFVSVMSIWVVTGALVYLAIERIVQNDYEIEGHVMLATSGCAVIVNIIMAYILHHSTTLHPHGSGYHQIDEDGRSPVNHGHAHMLLGGHS---NTSVRAAFIHVIGDLLQSIGVMVAAIIIYVRPEYKVADPICTFLFSLFVLCTTVTILRDVFRILMEGSPKGIEFSSVKEVLLSVKAVKSMHCLHLWALTLGQSLVSVHLAIEEEADPQAILQEATDLLIAKFGFHSITIQVELYSEDMSHCSHCQDPSD 354

[Close]

BLAST of slc30a-8 vs. Ensembl Medaka
Match: slc30a8 (solute carrier family 30 member 8 [Source:NCBI gene;Acc:101174514])

HSP 1 Score: 341.273 bits (874), Expect = 4.604e-114
Identity = 171/357 (47.90%), Postives = 242/357 (67.79%), Query Frame = 1

Query:  220 SDHCHGPSEAI----GVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--------HGHTHGSSKSNNETDKEHGHS---------------HGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDP 1209
            ++HCH  S A        K A+++L V S++CL+FM+ EIVGG +A SLA+MTDAAHLLTD  SF+ISLF+++L+S+PAT+++SFGWHRAE++GAL+SV  IW+VTG+LVYLAV R+V+ +F IEG IMLITS   ++ N+IMA TLHQ           +HG S  N + +K+  +S                G++++ N +VRAAF+HVIGDL+QSI V I+A+VI+ +P+YKIADPICTF+FSILVL TT  I+RD ++VLMEGTP  + ++EV+     + GV  VHNL +W+LT+++  LS H+AID   +   +LR+ +      +    VTIQ+E        C  C++P
Sbjct:   32 AEHCHDNSRAQEDRETEKKVAKRRLYVVSVICLVFMVAEIVGGYLAGSLAVMTDAAHLLTDLTSFLISLFSLWLSSKPATQKLSFGWHRAEILGALLSVFTIWLVTGVLVYLAVERLVTDDFTIEGSIMLITSGCAVVANIIMAVTLHQSGHGHSHGGLGSHGHSHENGKPNKQMSNSVHSELIDMEQSLPDHGGRTQQANASVRAAFVHVIGDLLQSISVLISAIVIFFRPEYKIADPICTFLFSILVLCTTFTIMRDILLVLMEGTPSGVKYSEVRDRLLAVKGVTAVHNLHIWALTMNQAMLSAHVAIDDSADAQMVLREMTQACFSSYNFHSVTIQMERQADLKPGCSLCENP 388

[Close]

Query:  220 SDHCHGPSEAI----GVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQ--------HGHTHGSSKSNNETDKEHGHS---------------HGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDP 1209
            ++HCH  S A        K A+++L V S++CL+FM+ EIVGG +A SLA+MTDAAHLLTD  SF+ISLF+++L+S+PAT+++SFGWHRAE++GAL+SV  IW+VTG+LVYLAV R+V+ +F IEG IMLITS   ++ N+IMA TLHQ           +HG S  N + +K+  +S                G++++ N +VRAAF+HVIGDL+QSI V I+A+VI+ +P+YKIADPICTF+FSILVL TT  I+RD ++VLMEGTP  + ++EV+     + GV  VHNL +W+LT+++  LS H+AID   +   +LR+ +      +    VTIQ+E        C  C++P
Sbjct:   32 AEHCHDNSRAQEDRETEKKVAKRRLYVVSVICLVFMVAEIVGGYLAGSLAVMTDAAHLLTDLTSFLISLFSLWLSSKPATQKLSFGWHRAEILGALLSVFTIWLVTGVLVYLAVERLVTDDFTIEGSIMLITSGCAVVANIIMAVTLHQSGHGHSHGGLGSHGHSHENGKPNKQMSNSVHSELIDMEQSLPDHGGRTQQANASVRAAFVHVIGDLLQSISVLISAIVIFFRPEYKIADPICTFLFSILVLCTTFTIMRDILLVLMEGTPSGVKYSEVRDRLLAVKGVTAVHNLHIWALTMNQAMLSAHVAIDDSADAQMVLREMTQACFSSYNFHSVTIQMERQADLKPGCSLCENP 388

[Close]

BLAST of slc30a-8 vs. Ensembl Medaka
Match: slc30a4 (solute carrier family 30 member 4 [Source:NCBI gene;Acc:101171398])

HSP 1 Score: 250.366 bits (638), Expect = 4.063e-78
Identity = 141/346 (40.75%), Postives = 214/346 (61.85%), Query Frame = 1

Query:  214 DFSDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKE----------HGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPD--QETHTILRDASNMLRQRFQIADVTIQLENYVSEMAE-CQQCQDPA 1212
            D  D+C    E I   +   K+L++A++L  +FM GEI+GG +++SLAIMTDA H+L D    + SL A++L+++P TKR +FG HR EVV A++SV++I+++TG+L+Y AV R V  +F I+G +MLIT+  G+ +NLIM   L+Q GH H  S  +  +              G  HG     ++ VRAAFIH +GDL+QS+GV IAA V+  KP++K+ADPICT+IFS+LVL TTI I+RDT+V+++EG P+ LD   ++     L  V  +  L +W+LT  KTA  VH+ + P        +   A ++L   + ++  T+Q++ +   M   C  C  P+
Sbjct:   94 DPCDNCTKKRERIK-HRRVMKRLVIAALLYFLFMTGEIIGGYVSNSLAIMTDAVHMLADVVGILFSLLALWLSTKPPTKRFTFGLHRLEVVSAVLSVVLIYILTGVLLYEAVQRTVHQDFSIDGDVMLITAAVGVAVNLIMGFLLNQGGHLHSHSHGHGHSHSSAAAAGSRPAGSGQPHG-----SLAVRAAFIHALGDLLQSVGVLIAAYVVRFKPEFKLADPICTYIFSVLVLFTTIRIIRDTIVIVLEGVPRHLDTQRIREDLLKLEDVQSIDELNVWALTADKTAAIVHLQLTPSSGHSWEDVQAKARHLLLHTYGLSRCTVQVQTHRERMVRSCANCLQPS 433

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BLAST of slc30a-8 vs. Ensembl Medaka
Match: slc30a5 (solute carrier family 30 member 5 [Source:NCBI gene;Acc:101161255])

HSP 1 Score: 115.546 bits (288), Expect = 3.144e-27
Identity = 76/298 (25.50%), Postives = 151/298 (50.67%), Query Frame = 1

Query:  295 ILCL--IFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKEN---INVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLD--FNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLEN 1167
             LCL   F   E+  G   +SL +++D  H+L D ++ ++ LFA  +    AT+  S+G+ R E++   ++ L + V+   +   +V R++     I   ++   S+ G+++NL+       H H+HG     +    +HGHSHG+ + E    ++    F+HV+ D + S+GV I+ L+I  +  + IADPIC+   + L+ ++ I +L++   VL+  TP + +   N        L GV+   +   W  + +  A ++H+ +  D     I +  + +L+    + ++++Q+E 
Sbjct:  362 FLCLNLAFTFVELFYGVWTNSLGLISDGFHMLFDCSALVLGLFAALMTRWKATRIFSYGFGRVEILSGFINGLFLMVIAFFVFMESVTRLLDPP-NINTDMLTPVSVGGLLVNLVGICAF-SHAHSHGGKSCQSH---DHGHSHGERDPEPNALMSSAGVFLHVLADTLGSVGVIISTLLIR-QFGWLIADPICSLFIATLIFLSVIPLLKEACEVLLLRTPPEHEKVLNGALEKIDKLEGVLSHRDAHFWRHSANMVAGTIHLQVMSDVVEQRITQQVTALLKDA-GVNNLSVQVEK 652

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BLAST of slc30a-8 vs. Planmine SMEST
Match: SMESG000013136.1 (SMESG000013136.1)

HSP 1 Score: 791.956 bits (2044), Expect = 0.000e+0
Identity = 384/384 (100.00%), Postives = 384/384 (100.00%), Query Frame = 1

Query:   64 MAKEFVKRNIPSVVRGAIFHEHKEDQQVLIENDACINYYGSSTGITRTSSDFSDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 1215
            MAKEFVKRNIPSVVRGAIFHEHKEDQQVLIENDACINYYGSSTGITRTSSDFSDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD
Sbjct:    1 MAKEFVKRNIPSVVRGAIFHEHKEDQQVLIENDACINYYGSSTGITRTSSDFSDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD 384

[Close]

BLAST of slc30a-8 vs. Planmine SMEST
Match: SMESG000022672.1 (SMESG000022672.1)

HSP 1 Score: 450.669 bits (1158), Expect = 4.132e-157
Identity = 227/385 (58.96%), Postives = 285/385 (74.03%), Query Frame = 1

Query:  133 EDQQVLIENDACINYYGSSTGITRTSSDFSDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHG--------------------------HSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDP 1209
            +D  ++IE +  I    S   +    +  +DHCH  SE  G+D+ AR+KLL+AS LCLIFMI EIVGG +A+SLAIMTDAAHLL+DFASFMISLFA++LASRPATKRMSFGWHRAEV+GALVSVL+IWVVTGILVY+AV+R+++ ++ IE  IMLITS  G+++NLIMA +LHQH H+H +   N    +E+                            S+    K NINVRAAFIHVIGDLVQS GV IAA VIY KP +KIADPICTFIFSILVL TTINILRDTM VLMEGTPK LDF++VK    +L GV+ +HNLR+WSLT +KTALSVH+A+DP++E   IL++A+ +L  +F I+D TIQLENYV++M +C++C+ P
Sbjct:    7 QDDSLIIEENGNIEIANSE--LAHRDNIETDHCHSDSETDGIDRVARRKLLIASGLCLIFMIAEIVGGTLANSLAIMTDAAHLLSDFASFMISLFALFLASRPATKRMSFGWHRAEVMGALVSVLLIWVVTGILVYMAVLRIMNKDYNIEATIMLITSGVGVLVNLIMACSLHQHSHSHETHPHNEPLSEEYDVENAQYSDSDALLDDDKKSDLVEVRIKSNNPIRKTNINVRAAFIHVIGDLVQSFGVLIAAFVIYYKPSWKIADPICTFIFSILVLCTTINILRDTMNVLMEGTPKSLDFDDVKETLLELEGVVLLHNLRIWSLTTNKTALSVHLAVDPNKEVQVILKEATRVLMSKFHISDATIQLENYVADMDDCKKCKTP 389

[Close]

BLAST of slc30a-8 vs. Planmine SMEST
Match: SMESG000022672.1 (SMESG000022672.1)

HSP 1 Score: 450.669 bits (1158), Expect = 6.716e-157
Identity = 222/356 (62.36%), Postives = 274/356 (76.97%), Query Frame = 1

Query:  220 SDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHTHGSSKSNNETDKEHG--------------------------HSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQCQDP 1209
            +DHCH  SE  G+D+ AR+KLL+AS LCLIFMI EIVGG +A+SLAIMTDAAHLL+DFASFMISLFA++LASRPATKRMSFGWHRAEV+GALVSVL+IWVVTGILVY+AV+R+++ ++ IE  IMLITS  G+++NLIMA +LHQH H+H +   N    +E+                            S+    K NINVRAAFIHVIGDLVQS GV IAA VIY KP +KIADPICTFIFSILVL TTINILRDTM VLMEGTPK LDF++VK    +L GV+ +HNLR+WSLT +KTALSVH+A+DP++E   IL++A+ +L  +F I+D TIQLENYV++M +C++C+ P
Sbjct:   48 TDHCHSDSETDGIDRVARRKLLIASGLCLIFMIAEIVGGTLANSLAIMTDAAHLLSDFASFMISLFALFLASRPATKRMSFGWHRAEVMGALVSVLLIWVVTGILVYMAVLRIMNKDYNIEATIMLITSGVGVLVNLIMACSLHQHSHSHETHPHNEPLSEEYDVENAQYSDSDALLDDDKKSDLVEVRIKSNNPIRKTNINVRAAFIHVIGDLVQSFGVLIAAFVIYYKPSWKIADPICTFIFSILVLCTTINILRDTMNVLMEGTPKSLDFDDVKETLLELEGVVLLHNLRIWSLTTNKTALSVHLAVDPNKEVQVILKEATRVLMSKFHISDATIQLENYVADMDDCKKCKTP 403

[Close]

BLAST of slc30a-8 vs. Planmine SMEST
Match: SMESG000002070.1 (SMESG000002070.1)

HSP 1 Score: 320.857 bits (821), Expect = 4.366e-106
Identity = 156/367 (42.51%), Postives = 235/367 (64.03%), Query Frame = 1

Query:  253 GVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGHT-------------------------------HGSSKSNNETDKEH-----------------GHSHGKSEK----ENINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLENYVSEMAECQQ 1197
             +D+ A+ KL++A +LC++F +GEI+GG +A+SLAI+TD+AHL +D +SF+ISL A+ L++R +TK M+FGWHRAE++GAL SVL+IW+VTG+L+Y A++R+++  + I   IMLI S  G+IIN+++A  LH   H                                  S   N+  D EH                 G    KS+     +NIN+RAAFIHVIGD++QS GV  AA +IY KP++KIADPICTF+FS LV++TTI I RD + VL+E  P+ +++N+V      +PG++++HNLR+WS+T++KTALS H+ +D  Q++ +IL    +M  + F+I+++TIQ+E+     A C Q
Sbjct:   37 NMDRQAKTKLIIAVVLCILFFMGEIIGGIIANSLAILTDSAHLFSDLSSFLISLGAMCLSARQSTKSMNFGWHRAEIIGALFSVLLIWIVTGVLIYAAILRIINSNYVINANIMLIMSAVGVIINVLLALVLHPQSHGHSHGGGGHGHSHGHGHSNGGGGHGHGHGHGHRASVNHNHSQDVEHCQDSDEPLLTTNSDVCAGEDSSKSKVFKSIDNINLRAAFIHVIGDIIQSFGVLAAAFIIYFKPQWKIADPICTFLFSFLVMLTTIFIFRDVIYVLLERKPRHINYNKVTIRISSIPGIVQIHNLRLWSITLTKTALSCHLVVDASQDSQSILEKVYDMCIEEFKISEITIQIESSAKPSALCDQ 403

[Close]

BLAST of slc30a-8 vs. Planmine SMEST
Match: SMESG000075723.1 (SMESG000075723.1)

HSP 1 Score: 147.517 bits (371), Expect = 2.069e-39
Identity = 91/332 (27.41%), Postives = 172/332 (51.81%), Query Frame = 1

Query:  295 ILCLIFMIGEIVGGAMASSLAIMTDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMIWVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATL-HQHGHTHGS--------------------SKSNNETDKE--------HGHSHGKSEKE---NINVRAAFIHVIGDLVQSIGVFIAALVIYLKPKYK----------IADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFNEVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDASNMLRQRFQIADVTIQLE 1164
            +L L++ + E++ G M +S+ ++ D+ H+L+DF + +I + A  +   P + + +FGW RAEVVG+LV+ +M+  +T  ++  ++ R +  E   +  I+    + G+++N+I    L + HGH+HG                     S   N  D +         G +HG S+K+   ++N+RA ++HV+ DL  SI V I+A+V++  P ++          + DP+ + +  +L+LI+T+ +L+ + ++L++  PKD+   E+K    ++ G+ +VH+L +W L       +VHI      E +         L   F+I   TIQ E
Sbjct:    3 VLVLLYFLVELIVGHMLNSITLIADSFHMLSDFIALIIGIAARRIGKWPKSSKNTFGWQRAEVVGSLVNTVMLTTLTFTILIKSIQRFIQPEEIEKPHIIFYVGLGGLLVNIIGLIILRNHHGHSHGPETAILLKEEEEELVDDDIPESPVPNLVDGDVKIVIKDNEGENHGHSQKKGASHMNMRAVYLHVLADLFGSIAVVISAIVLWQVPNFQNPPKTDYWKLMVDPLISVLMVVLILISTVPLLKQSALILLQSVPKDVSIKELKDRMENIEGIEKVHDLHVWLLQSDVIIGTVHIRC--SNENYVTASKKVKKLFHEFRIHCTTIQAE 332

The following BLAST results are available for this feature:

BLAST of slc30a-8 vs. Ensembl Human
BLAST of slc30a-8 vs. Ensembl Celegans
BLAST of slc30a-8 vs. Ensembl Fly
BLAST of slc30a-8 vs. Ensembl Zebrafish
BLAST of slc30a-8 vs. Ensembl Xenopus
BLAST of slc30a-8 vs. Ensembl Mouse
BLAST of slc30a-8 vs. UniProt/SwissProt
BLAST of slc30a-8 vs. TrEMBL
BLAST of slc30a-8 vs. Ensembl Cavefish
BLAST of slc30a-8 vs. Ensembl Sea Lamprey
BLAST of slc30a-8 vs. Ensembl Yeast
BLAST of slc30a-8 vs. Ensembl Nematostella
BLAST of slc30a-8 vs. Ensembl Medaka
BLAST of slc30a-8 vs. Planmine SMEST

BLAST of slc30a-8 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SLC30A2	3.401e-128	50.52	solute carrier family 30 member 2 [Source:HGNC Sym...	[more]
SLC30A3	2.255e-108	46.61	solute carrier family 30 member 3 [Source:HGNC Sym...	[more]
SLC30A8	5.978e-98	46.41	solute carrier family 30 member 8 [Source:HGNC Sym...	[more]
SLC30A8	5.978e-98	46.41	solute carrier family 30 member 8 [Source:HGNC Sym...	[more]
SLC30A8	5.978e-98	46.41	solute carrier family 30 member 8 [Source:HGNC Sym...	[more]

BLAST of slc30a-8 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cdf-2	2.862e-114	47.37	Cation Diffusion Facilitator family [Source:UniPr...	[more]
ttm-1	4.818e-83	44.17	Toxin-regulated Targets of MAPK [Source:UniProtKB...	[more]
ttm-1	6.002e-83	45.86	Toxin-regulated Targets of MAPK [Source:UniProtKB...	[more]
ttm-1	2.198e-82	45.86	Toxin-regulated Targets of MAPK [Source:UniProtKB...	[more]
Y105E8A.3	2.480e-12	23.08	pep chromosome:WBcel235:I:14358502:14367594:1 gene...	[more]

BLAST of slc30a-8 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ZnT33D	8.380e-111	49.58	gene:FBgn0051860 transcript:FBtr0302984	[more]
ZnT35C	1.291e-56	56.47	gene:FBgn0028516 transcript:FBtr0080715	[more]
ZnT35C	3.122e-56	62.33	gene:FBgn0028516 transcript:FBtr0080714	[more]
ZnT33D	5.815e-38	55.75	gene:FBgn0051860 transcript:FBtr0302985	[more]
ZnT41F	2.996e-34	49.23	gene:FBgn0025693 transcript:FBtr0086054	[more]

BLAST of slc30a-8 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc30a2	1.036e-127	47.78	solute carrier family 30 member 2 [Source:ZFIN;Acc...	[more]
slc30a2	2.292e-127	51.76	solute carrier family 30 member 2 [Source:ZFIN;Acc...	[more]
slc30a2	1.831e-123	51.50	solute carrier family 30 member 2 [Source:ZFIN;Acc...	[more]
slc30a8	1.708e-118	48.61	solute carrier family 30 member 8 [Source:ZFIN;Acc...	[more]
slc30a8	1.780e-118	48.35	solute carrier family 30 member 8 [Source:ZFIN;Acc...	[more]

BLAST of slc30a-8 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc30a2	2.831e-141	57.69	solute carrier family 30 member 2 [Source:NCBI gen...	[more]
slc30a2	3.162e-141	57.69	solute carrier family 30 member 2 [Source:NCBI gen...	[more]
ENSXETT00000033890.1	9.585e-125	51.91	solute carrier family 30 (zinc transporter), membe...	[more]
nbr1	3.335e-110	48.82	neighbor of BRCA1 gene 1 [Source:Xenbase;Acc:XB-GE...	[more]
gmip	2.025e-80	41.00	GEM interacting protein [Source:Xenbase;Acc:XB-GEN...	[more]

BLAST of slc30a-8 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Slc30a2	3.425e-127	55.94	solute carrier family 30 (zinc transporter), membe...	[more]
Slc30a2	1.869e-119	55.78	solute carrier family 30 (zinc transporter), membe...	[more]
Slc30a2	1.869e-119	55.78	solute carrier family 30 (zinc transporter), membe...	[more]
Slc30a3	1.035e-105	47.02	solute carrier family 30 (zinc transporter), membe...	[more]
Slc30a3	3.169e-105	47.02	solute carrier family 30 (zinc transporter), membe...	[more]

BLAST of slc30a-8 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q2HJ10\|ZNT2_MOUSE	2.396e-126	55.94	Zinc transporter 2 OS=Mus musculus OX=10090 GN=Slc...	[more]
sp\|Q62941\|ZNT2_RAT	3.599e-119	52.54	Zinc transporter 2 OS=Rattus norvegicus OX=10116 G...	[more]
sp\|Q5XHB4\|ZNT8_XENTR	2.599e-108	48.52	Zinc transporter 8 OS=Xenopus tropicalis OX=8364 G...	[more]
sp\|Q08E25\|ZNT3_BOVIN	3.869e-108	46.90	Zinc transporter 3 OS=Bos taurus OX=9913 GN=SLC30A...	[more]
sp\|Q99726\|ZNT3_HUMAN	1.083e-107	46.61	Zinc transporter 3 OS=Homo sapiens OX=9606 GN=SLC3...	[more]

BLAST of slc30a-8 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0H3YKE4	0.000e+0	100.00	Slc30a-8 OS=Schmidtea mediterranea OX=79327 GN=slc...	[more]
A0A504YFT6	3.166e-157	60.55	Zinc transporter OS=Fasciola gigantica OX=46835 GN...	[more]
A0A267DB27	2.041e-155	62.29	Uncharacterized protein (Fragment) OS=Macrostomum ...	[more]
A0A267DEN5	4.677e-155	62.29	Uncharacterized protein (Fragment) OS=Macrostomum ...	[more]
A0A4E0RCI3	6.703e-155	60.00	Zinc transporter OS=Fasciola hepatica OX=6192 GN=D...	[more]

BLAST of slc30a-8 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc30a2	4.299e-126	49.30	zinc transporter 2 [Source:NCBI gene;Acc:103036936...	[more]
slc30a8	6.510e-123	47.09	solute carrier family 30 member 8 [Source:ZFIN;Acc...	[more]
SLC30A2	7.570e-112	48.35	zinc transporter 2-like [Source:NCBI gene;Acc:1030...	[more]
SLC30A2	9.990e-112	48.35	zinc transporter 2-like [Source:NCBI gene;Acc:1030...	[more]
slc30a8	2.972e-109	45.53	solute carrier family 30 member 8 [Source:ZFIN;Acc...	[more]

BLAST of slc30a-8 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc30a2	3.558e-117	51.08	solute carrier family 30 member 2 [Source:ZFIN;Acc...	[more]
slc30a2	3.791e-63	53.97	solute carrier family 30 member 2 [Source:ZFIN;Acc...	[more]
slc30a2	3.600e-56	52.98	solute carrier family 30 member 2 [Source:ZFIN;Acc...	[more]
slc30a10	7.915e-28	26.52	solute carrier family 30 member 10 [Source:ZFIN;Ac...	[more]
slc30a10	4.138e-23	24.50	solute carrier family 30 member 10 [Source:ZFIN;Ac...	[more]

BLAST of slc30a-8 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4


Match Name	E-value	Identity	Description
ZRC1	1.237e-27	25.74	Vacuolar membrane zinc transporter; transports zin...	[more]
COT1	5.676e-16	27.71	Vacuolar transporter that mediates zinc transport ...	[more]
MSC2	2.396e-9	24.29	Endoplasmic reticulum zinc transporter; part of a ...	[more]
MMT2	2.058e-7	36.11	Putative metal transporter involved in mitochondri...	[more]

BLAST of slc30a-8 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO30554	9.971e-124	54.40	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43612	4.619e-114	55.35	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48857	1.315e-65	34.75	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34617	7.243e-18	19.65	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO29786	5.765e-7	27.12	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of slc30a-8 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc30a2	7.164e-122	48.88	solute carrier family 30 member 3 [Source:NCBI gen...	[more]
slc30a8	4.604e-114	47.90	solute carrier family 30 member 8 [Source:NCBI gen...	[more]
slc30a8	4.604e-114	47.90	solute carrier family 30 member 8 [Source:NCBI gen...	[more]
slc30a4	4.063e-78	40.75	solute carrier family 30 member 4 [Source:NCBI gen...	[more]
slc30a5	3.144e-27	25.50	solute carrier family 30 member 5 [Source:NCBI gen...	[more]

BLAST of slc30a-8 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000013136.1	0.000e+0	100.00	SMESG000013136.1	[more]
SMESG000022672.1	4.132e-157	58.96	SMESG000022672.1	[more]
SMESG000022672.1	6.716e-157	62.36	SMESG000022672.1	[more]
SMESG000002070.1	4.366e-106	42.51	SMESG000002070.1	[more]
SMESG000075723.1	2.069e-39	27.41	SMESG000075723.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30003463
GenBank	AKN21628.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30003463 ID=SMED30003463|Name=slc30a-8|organism=Schmidtea mediterranea sexual|type=transcript|length=1361bp
GAAAGCACCTGCACCCTTTCTCAATTTACATATAGTTGAATTATATTCCA
TCATCACTAGAAAATGGCCAAAGAGTTTGTGAAAAGAAATATCCCATCAG
TTGTCAGAGGAGCCATATTTCATGAACACAAAGAAGATCAACAGGTGCTA
ATAGAAAACGATGCGTGCATAAATTACTATGGTTCGAGTACGGGAATAAC
AAGAACATCGAGTGATTTTAGTGATCATTGCCATGGTCCCTCAGAAGCCA
TAGGTGTGGATAAAAATGCAAGAAAAAAATTATTAGTGGCAAGTATTTTA
TGCTTAATTTTCATGATTGGAGAAATTGTAGGAGGAGCAATGGCAAGTAG
TTTAGCTATCATGACAGATGCAGCTCATTTGCTGACAGATTTTGCAAGCT
TTATGATAAGTTTGTTTGCTATTTATTTGGCGTCCAGACCCGCAACAAAA
CGAATGAGTTTCGGTTGGCACAGAGCTGAAGTAGTTGGCGCTTTGGTATC
AGTTCTCATGATATGGGTGGTTACAGGAATTCTCGTCTATTTAGCGGTTA
TGCGAGTTGTCAGCATGGAATTTAAAATCGAAGGCGGAATTATGCTGATT
ACGTCTATTGCTGGGATAATTATTAATCTAATAATGGCTGCCACACTTCA
TCAACATGGTCATACACATGGGTCCAGTAAATCTAATAATGAAACGGACA
AGGAGCATGGTCATAGTCATGGGAAATCCGAAAAAGAAAACATCAATGTT
CGCGCAGCCTTTATACATGTTATAGGTGATTTAGTACAAAGTATCGGAGT
ATTTATTGCAGCTCTTGTCATTTATCTCAAGCCAAAATACAAAATTGCAG
ATCCAATATGCACATTCATCTTCTCCATTTTGGTCCTGATTACTACAATT
AATATTCTACGAGACACTATGGTTGTTTTGATGGAGGGGACACCCAAAGA
TTTAGATTTCAATGAAGTAAAGGCAGCATTCTATGATTTACCTGGAGTAA
TTGAAGTTCATAATTTACGAATGTGGAGTTTAACAATAAGTAAAACTGCT
CTTTCCGTTCACATTGCTATAGATCCTGATCAAGAAACGCATACTATTCT
ACGAGATGCCAGCAATATGCTAAGACAGAGATTCCAGATCGCCGACGTAA
CAATCCAGCTAGAGAACTATGTAAGTGAAATGGCAGAATGCCAACAATGC
CAAGATCCGGCAGATTAATTGTCTGTTATAAATGAAACTGGTTGCTGATT
TTATTATCAATTATGTGAAATTCTTGTTATCACTTAATATTTAGATGATT
ACTGTCGTTTTGTCGATTGTGTTTTGTTTTATCGTTAGAATAAATATTTA
ACGTTTTGAAA

protein sequence of SMED30003463-orf-1

>SMED30003463-orf-1 ID=SMED30003463-orf-1|Name=SMED30003463-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=385bp
MAKEFVKRNIPSVVRGAIFHEHKEDQQVLIENDACINYYGSSTGITRTSS
DFSDHCHGPSEAIGVDKNARKKLLVASILCLIFMIGEIVGGAMASSLAIM
TDAAHLLTDFASFMISLFAIYLASRPATKRMSFGWHRAEVVGALVSVLMI
WVVTGILVYLAVMRVVSMEFKIEGGIMLITSIAGIIINLIMAATLHQHGH
THGSSKSNNETDKEHGHSHGKSEKENINVRAAFIHVIGDLVQSIGVFIAA
LVIYLKPKYKIADPICTFIFSILVLITTINILRDTMVVLMEGTPKDLDFN
EVKAAFYDLPGVIEVHNLRMWSLTISKTALSVHIAIDPDQETHTILRDAS
NMLRQRFQIADVTIQLENYVSEMAECQQCQDPAD*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR036837	Cation_efflux_CTD_sf
IPR027470	Cation_efflux_CTD
IPR027469	Cation_efflux_TMD_sf
IPR002524	Cation_efflux
IPR009057	Homeobox-like_sf

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0016020	membrane

Vocabulary: **molecular function**
Term	Definition
GO:0008324	cation transmembrane transporter activity
GO:0003677	DNA binding

Vocabulary: **biological process**
Term	Definition
GO:0006812	cation transport
GO:0055085	transmembrane transport
GO:0098655	cation transmembrane transport

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002524	Cation efflux protein	PFAM	PF01545	Cation_efflux	coord: 73..290 e-value: 2.5E-48 score: 164.5
IPR002524	Cation efflux protein	TIGRFAM	TIGR01297	TIGR01297	coord: 70..369 e-value: 4.8E-89 score: 296.4
IPR027469	Cation efflux transmembrane domain superfamily	GENE3D	G3DSA:1.20.1510.10		coord: 69..290 e-value: 1.9E-28 score: 101.4
IPR027469	Cation efflux transmembrane domain superfamily	SUPERFAMILY	SSF161111	Cation efflux protein transmembrane domain-like	coord: 67..291
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 201..223
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 203..223
None	No IPR available	PANTHER	PTHR11562	CATION EFFLUX PROTEIN/ ZINC TRANSPORTER	coord: 39..382
None	No IPR available	PANTHER	PTHR11562:SF84	LD05335P	coord: 39..382
None	No IPR available	TMHMM	TMhelix		coord: 73..95
None	No IPR available	TMHMM	TMhelix		coord: 265..282
None	No IPR available	TMHMM	TMhelix		coord: 110..127
None	No IPR available	TMHMM	TMhelix		coord: 172..194
None	No IPR available	TMHMM	TMhelix		coord: 140..162
None	No IPR available	TMHMM	TMhelix		coord: 233..255
IPR036837	Cation efflux protein, cytoplasmic domain superfamily	SUPERFAMILY	SSF160240	Cation efflux protein cytoplasmic domain-like	coord: 295..367