Ras-related protein Rab-27B

Overview


Name	Ras-related protein Rab-27B
Smed ID	SMED30003458
Length (bp)	722

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Ras-related protein Rab-27B (SMED30003458) t-SNE clustered cells

Violin plots show distribution of expression levels for Ras-related protein Rab-27B (SMED30003458) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ras-related protein Rab-27B (SMED30003458) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ras-related protein Rab-27B (SMED30003458) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30003458

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30003458	SMESG000077907.1	dd_Smed_v4_10266_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30003458	SMESG000077907.1	dd_Smed_v4_10266_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30003458	SMESG000077907.1	dd_Smed_v4_10266_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30003458	SMESG000077907.1 SMESG000077905.1 SMESG000009337.1	Contig39604	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30003458	SMESG000077907.1 SMESG000077905.1 SMESG000009337.1	Contig39604	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
epidermis	SMED30003458	SMESG000077907.1	dd_Smed_v4_10266_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Ras-related protein Rab-27B vs. Ensembl Human
Match: RAB27B (RAB27B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9767])

HSP 1 Score: 236.884 bits (603), Expect = 1.840e-78
Identity = 109/193 (56.48%), Postives = 149/193 (77.20%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITN 632
            +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+++ +     S  G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+L+GNKADLP  R V E  A+++A ++ +PY ETS   G  VE+A++ L++++M R+E  +   +I +
Sbjct:    5 DYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYNAQGPNGSS-GKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELADKYGIPYFETSAATGQNVEKAVETLLDLIMKRMEQCVEKTQIPD 196

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BLAST of Ras-related protein Rab-27B vs. Ensembl Human
Match: RAB27A (RAB27A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9766])

HSP 1 Score: 228.024 bits (580), Expect = 6.587e-75
Identity = 103/188 (54.79%), Postives = 143/188 (76.06%), Query Frame = 3

Query:   54 NDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            + +YDYLI+ LALGD  VGKT+ LY YTDGKF+  F +T+G+DFR+KR+++R+    D   G  Q +HLQLWDTAGQERFRSL + FFRDAMGF+L+FDLTNE+S LNVR W++ L+ +AYC+NPDI+L GNK+DL   R V EE A  +A+++ +PY ETS  NG  + +A++ L++++M R+E  +
Sbjct:    3 DGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRA-SGPDGATGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRMERCV 189

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Query:   54 NDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            + +YDYLI+ LALGD  VGKT+ LY YTDGKF+  F +T+G+DFR+KR+++R+    D   G  Q +HLQLWDTAGQERFRSL + FFRDAMGF+L+FDLTNE+S LNVR W++ L+ +AYC+NPDI+L GNK+DL   R V EE A  +A+++ +PY ETS  NG  + +A++ L++++M R+E  +
Sbjct:    3 DGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRA-SGPDGATGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRMERCV 189

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Query:   54 NDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            + +YDYLI+ LALGD  VGKT+ LY YTDGKF+  F +T+G+DFR+KR+++R+    D   G  Q +HLQLWDTAGQERFRSL + FFRDAMGF+L+FDLTNE+S LNVR W++ L+ +AYC+NPDI+L GNK+DL   R V EE A  +A+++ +PY ETS  NG  + +A++ L++++M R+E  +
Sbjct:    3 DGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRA-SGPDGATGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRMERCV 189

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Query:   54 NDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            + +YDYLI+ LALGD  VGKT+ LY YTDGKF+  F +T+G+DFR+KR+++R+    D   G  Q +HLQLWDTAGQERFRSL + FFRDAMGF+L+FDLTNE+S LNVR W++ L+ +AYC+NPDI+L GNK+DL   R V EE A  +A+++ +PY ETS  NG  + +A++ L++++M R+E  +
Sbjct:    3 DGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRA-SGPDGATGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRMERCV 189

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BLAST of Ras-related protein Rab-27B vs. Ensembl Celegans
Match: aex-6 (Rab27 [Source:UniProtKB/TrEMBL;Acc:G5EBS5])

HSP 1 Score: 209.149 bits (531), Expect = 5.487e-68
Identity = 99/186 (53.23%), Postives = 137/186 (73.66%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +YDYLI+ LALGD  VGKT+FL+ YTD  F   F ST+G+DF++K+++++S        G  Q + LQLWDTAGQERFRSL + FFRDAMGF+L+FD+TNE+S LN+R+W++ LK +AYC+ PDII+ GNKADL   R V+   AK++A +  LPY ETS      VE+++D L+++VM RI+ S+
Sbjct:    3 DYDYLIKFLALGDSGVGKTSFLHRYTDNTFTGQFISTVGIDFKEKKVVYKSSRGGFG--GRGQRVLLQLWDTAGQERFRSLTTAFFRDAMGFILIFDITNEQSFLNIRDWLSQLKVHAYCEQPDIIICGNKADLENRRQVSTARAKQLADQLGLPYFETSACTSTNVEKSVDCLLDLVMQRIQQSV 186

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BLAST of Ras-related protein Rab-27B vs. Ensembl Celegans
Match: rab-3 (Ras-related protein Rab-3 [Source:UniProtKB/Swiss-Prot;Acc:Q94986])

HSP 1 Score: 145.591 bits (366), Expect = 3.648e-43
Identity = 69/185 (37.30%), Postives = 118/185 (63.78%), Query Frame = 3

Query:   63 YDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +DY+ +LL +G+  VGKT+FL+ Y D  F   F ST+G+DF+ K +            G++++  LQ+WDTAGQER+R++ + ++R AMGF+LM+D+TNEES  +V++W   +K  ++ +N  ++LVGNK D+   R V+ +  +++A +  L + ETS    I V+   +KLV ++  ++  S+
Sbjct:   19 FDYMFKLLIIGNSSVGKTSFLFRYCDDSFTSAFVSTVGIDFKVKTVFR----------GDKRV-KLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNSVQDWCTQIKTYSW-ENAQVVLVGNKCDMDSERVVSMDRGRQLADQLGLEFFETSAKENINVKAVFEKLVEIICDKMAESL 191

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BLAST of Ras-related protein Rab-27B vs. Ensembl Celegans
Match: rab-3 (Ras-related protein Rab-3 [Source:UniProtKB/Swiss-Prot;Acc:Q94986])

HSP 1 Score: 145.976 bits (367), Expect = 4.784e-43
Identity = 69/185 (37.30%), Postives = 118/185 (63.78%), Query Frame = 3

Query:   63 YDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +DY+ +LL +G+  VGKT+FL+ Y D  F   F ST+G+DF+ K +            G++++  LQ+WDTAGQER+R++ + ++R AMGF+LM+D+TNEES  +V++W   +K  ++ +N  ++LVGNK D+   R V+ +  +++A +  L + ETS    I V+   +KLV ++  ++  S+
Sbjct:   33 FDYMFKLLIIGNSSVGKTSFLFRYCDDSFTSAFVSTVGIDFKVKTVFR----------GDKRV-KLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNSVQDWCTQIKTYSW-ENAQVVLVGNKCDMDSERVVSMDRGRQLADQLGLEFFETSAKENINVKAVFEKLVEIICDKMAESL 205

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BLAST of Ras-related protein Rab-27B vs. Ensembl Celegans
Match: rab-1 (RAB family [Source:UniProtKB/TrEMBL;Acc:Q9UAQ6])

HSP 1 Score: 135.191 bits (339), Expect = 2.773e-39
Identity = 70/188 (37.23%), Postives = 115/188 (61.17%), Query Frame = 3

Query:   42 VMARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRI 599
            + A N EYDYL +LL +GD  VGK+  L  + D  +   + STIGVDF+ + I    +D         + + LQ+WDTAGQERFR++ S ++R A G ++++D+T++E+  NV++W+  +   A C+N + +LVGNK DL   R V  +AA+  A +  +P++ETS  +   VE+A   + + + +R+
Sbjct:    1 MAAMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTI---ELDG--------KTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDITDQETFNNVKQWLQEIDRYA-CENVNKLLVGNKCDLTAKRAVETQAAQDYAGQLGIPFLETSAKSSTNVEQAFLTMASEIKSRM 176

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BLAST of Ras-related protein Rab-27B vs. Ensembl Celegans
Match: 4R79.2 (pep chromosome:WBcel235:IV:17480396:17482329:-1 gene:WBGene00007067.1 transcript:4R79.2b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:4R79.2)

HSP 1 Score: 134.035 bits (336), Expect = 1.296e-37
Identity = 72/187 (38.50%), Postives = 110/187 (58.82%), Query Frame = 3

Query:   66 DYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNK-----ADLPRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            D + +++ +GD  VGKT FL+ +   +F P F +TIGVDF  K +           +   + + +QLWDTAGQERFRS+   +FR A G VLMFD+T+E+S LNVR W++ ++A    D   + LVGNK     +D+ R+    AA+K+A EF +P+ ETS   G  ++  M ++   +  R +N +
Sbjct:  116 DRIFKVVFVGDSAVGKTCFLHRFCHNRFKPLFNATIGVDFTVKTMK----------IPPNRAIAMQLWDTAGQERFRSITKQYFRKADGVVLMFDVTSEQSFLNVRNWIDSVRAGVD-DATVMCLVGNKMDLFGSDIARSAVYRAAEKLAVEFKIPFFETSAYTGFGIDTCMRQMAENLQRREDNHL 291

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BLAST of Ras-related protein Rab-27B vs. Ensembl Fly
Match: Rab27 (gene:FBgn0025382 transcript:FBtr0070294)

HSP 1 Score: 201.445 bits (511), Expect = 1.148e-64
Identity = 95/194 (48.97%), Postives = 132/194 (68.04%), Query Frame = 3

Query:   54 NDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKIT 629
            N +YDYL++ L LGD  VGKT  LY YTDG+F   F ST+G+DFR+KR+++ S        G    +HLQ+WDTAGQERFRSL + F+RDAMGF+L+FDLT+E+S L    W++ L+ +AY ++PD++L GNK DL   R V+ +    + + + LPYIETS   G  V+EA++ LV  VM RIEN+  N + +
Sbjct:    5 NIDYDYLLKFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYNS-------RGRRHRIHLQIWDTAGQERFRSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDVVLCGNKCDLLQLRVVSRDQVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMERIENAACNREFS 191

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BLAST of Ras-related protein Rab-27B vs. Ensembl Fly
Match: Rab27 (gene:FBgn0025382 transcript:FBtr0070293)

HSP 1 Score: 189.889 bits (481), Expect = 4.696e-60
Identity = 90/186 (48.39%), Postives = 125/186 (67.20%), Query Frame = 3

Query:   78 RLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKIT 629
            + L LGD  VGKT  LY YTDG+F   F ST+G+DFR+KR+++ S        G    +HLQ+WDTAGQERFRSL + F+RDAMGF+L+FDLT+E+S L    W++ L+ +AY ++PD++L GNK DL   R V+ +    + + + LPYIETS   G  V+EA++ LV  VM RIEN+  N + +
Sbjct:   19 QFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYNS-------RGRRHRIHLQIWDTAGQERFRSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDVVLCGNKCDLLQLRVVSRDQVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMERIENAACNREFS 197

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BLAST of Ras-related protein Rab-27B vs. Ensembl Fly
Match: Rab3 (gene:FBgn0005586 transcript:FBtr0473383)

HSP 1 Score: 146.362 bits (368), Expect = 2.689e-43
Identity = 67/190 (35.26%), Postives = 120/190 (63.16%), Query Frame = 3

Query:   48 ARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            A +  +DY+ +LL +G+  VGKT+FL+ Y D  F   F ST+G+DF+ K +              ++ + LQ+WDTAGQER+R++ + ++R AMGF+LM+D+TNE+S  +V++W+  +K  ++ DN  +ILVGNK D+   R ++ E  +++A +  + + ETS    + V+   ++LV+++  ++  S+
Sbjct:   13 AADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFR-----------HDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSW-DNAQVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESL 190

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BLAST of Ras-related protein Rab-27B vs. Ensembl Fly
Match: Rab3 (gene:FBgn0005586 transcript:FBtr0088257)

HSP 1 Score: 146.362 bits (368), Expect = 2.689e-43
Identity = 67/190 (35.26%), Postives = 120/190 (63.16%), Query Frame = 3

Query:   48 ARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            A +  +DY+ +LL +G+  VGKT+FL+ Y D  F   F ST+G+DF+ K +              ++ + LQ+WDTAGQER+R++ + ++R AMGF+LM+D+TNE+S  +V++W+  +K  ++ DN  +ILVGNK D+   R ++ E  +++A +  + + ETS    + V+   ++LV+++  ++  S+
Sbjct:   13 AADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFR-----------HDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSW-DNAQVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESL 190

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BLAST of Ras-related protein Rab-27B vs. Ensembl Fly
Match: Rab8 (gene:FBgn0262518 transcript:FBtr0308833)

HSP 1 Score: 131.724 bits (330), Expect = 7.717e-38
Identity = 69/185 (37.30%), Postives = 115/185 (62.16%), Query Frame = 3

Query:   63 YDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            YDYL +LL +GD  VGKT  L+ +++  F+  F STIG+DF+ + I    +D         + + LQ+WDTAGQERFR++ + ++R AMG +L++D+T E+S  N++ W+  ++ NA  D  + +L+GNK +L   R V++E  +++A E+ + ++ETS    I VEEA   L + +  + E  +
Sbjct:    5 YDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTI---ELD--------NKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASAD-VEKMLLGNKCELTDKRQVSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRM 177

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BLAST of Ras-related protein Rab-27B vs. Ensembl Zebrafish
Match: rab27b (RAB27B, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-120215-85])

HSP 1 Score: 235.343 bits (599), Expect = 5.455e-78
Identity = 108/186 (58.06%), Postives = 146/186 (78.49%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+++ + +  +   G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+LVGNKADL   R V E+ AK++A ++ +PY ETS   G  V++A+  L+++VM R+E  +
Sbjct:   12 DYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVY-TTNSPNGTTGKTFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLVGNKADLADQREVQEKQAKELADKYGIPYFETSAATGSEVDKAVVTLLDLVMKRMEQCV 196

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BLAST of Ras-related protein Rab-27B vs. Ensembl Zebrafish
Match: rab27b (RAB27B, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-120215-85])

HSP 1 Score: 234.958 bits (598), Expect = 6.355e-78
Identity = 108/186 (58.06%), Postives = 146/186 (78.49%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+++ + +  +   G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+LVGNKADL   R V E+ AK++A ++ +PY ETS   G  V++A+  L+++VM R+E  +
Sbjct:   12 DYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVY-TTNSPNGTTGKTFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLVGNKADLADQREVQEKQAKELADKYGIPYFETSAATGSEVDKAVVTLLDLVMKRMEQCV 196

[Close]

BLAST of Ras-related protein Rab-27B vs. Ensembl Zebrafish
Match: rab27a (RAB27A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-050913-46])

HSP 1 Score: 226.868 bits (577), Expect = 1.094e-74
Identity = 103/186 (55.38%), Postives = 142/186 (76.34%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +YDYLI+ LALGD  VGKT+FLY YTD KF+  F +T+G+DFR+KR++++S    D   G  Q +H+QLWDTAGQERFRSL + FFRDAMGF+L+FDLTNE+S LNVR WM+ L+ +AYC+NPDI+L GNK+DL   R V  E A+++A+++ +PY ETS  NG  V  A++ L++++M R+E  +
Sbjct:    5 DYDYLIKFLALGDSGVGKTSFLYQYTDSKFNSKFITTVGIDFREKRVVYKS-SGPDGTAGRGQRIHIQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWMSQLQTHAYCENPDIVLCGNKSDLEEQRAVKAENARELAEKYGVPYFETSAANGENVSRAVEVLLDLIMKRMERCV 189

[Close]

BLAST of Ras-related protein Rab-27B vs. Ensembl Zebrafish
Match: rab3ab (RAB3A, member RAS oncogene family, b [Source:ZFIN;Acc:ZDB-GENE-041210-268])

HSP 1 Score: 150.599 bits (379), Expect = 8.922e-45
Identity = 68/185 (36.76%), Postives = 116/185 (62.70%), Query Frame = 3

Query:   63 YDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +DY+ ++L +G+  VGKT+FL+ Y D  F P F ST+G+DF+ K I              ++ + LQ+WDTAGQER+R++ + ++R AMGF+LM+D+TNEES   V++W   +K  ++ DN  ++LVGNK D+   R V  E  +++++     Y E S  + I V++  ++LV+++  ++  S+
Sbjct:   19 FDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRN-----------DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFAAVQDWSTQIKTYSW-DNAQVLLVGNKCDMEDERVVASERGRQLSEHLGFEYFEASAKDNINVKQTFERLVDIICEKMSESL 191

[Close]

BLAST of Ras-related protein Rab-27B vs. Ensembl Zebrafish
Match: rab3c (RAB3C, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-040718-263])

HSP 1 Score: 147.132 bits (370), Expect = 1.394e-43
Identity = 67/185 (36.22%), Postives = 118/185 (63.78%), Query Frame = 3

Query:   63 YDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +DY+ +LL +G+  VGKT+FL+ Y D  F   F ST+G+DF+ K +              ++ + LQ+WDTAGQER+R++ + ++R AMGF+LM+D+TNEES   V++W   +K  ++ DN  +IL GNK D+   R V+ ++ + +A++    + ETS  + I V++  D+LV+++  ++ +++
Sbjct:   17 FDYMFKLLIIGNSSVGKTSFLFRYADDTFTSAFVSTVGIDFKVKTVYKN-----------DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFAAVQDWATQIKTYSW-DNAQVILAGNKCDMEEERIVSVDSGRLLAEQLGFEFFETSAKDNINVKQTFDRLVDIICDKMSDTL 189

[Close]

BLAST of Ras-related protein Rab-27B vs. Ensembl Xenopus
Match: lemd3 (LEM domain containing 3 [Source:Xenbase;Acc:XB-GENE-486033])

HSP 1 Score: 233.032 bits (593), Expect = 4.705e-77
Identity = 108/193 (55.96%), Postives = 149/193 (77.20%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITN 632
            +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+I+ +     +  G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+L+GNKADL   R V E  AK++A ++ +PY ETS  +G  VE+++D L++++M R+E  +   ++ +
Sbjct:    5 DYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVIYSNAGPGGT-HGKTFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLSDQREVNERQAKELADKYGIPYFETSAASGQDVEKSVDTLLDLIMKRMEQCVDKTQVPD 196

[Close]

BLAST of Ras-related protein Rab-27B vs. Ensembl Xenopus
Match: lemd3 (LEM domain containing 3 [Source:Xenbase;Acc:XB-GENE-486033])

HSP 1 Score: 233.032 bits (593), Expect = 8.056e-76
Identity = 108/195 (55.38%), Postives = 150/195 (76.92%), Query Frame = 3

Query:   54 NDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITN 632
            + +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+I+ +     +  G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+L+GNKADL   R V E  AK++A ++ +PY ETS  +G  VE+++D L++++M R+E  +   ++ +
Sbjct:   93 DGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVIYSNAGPGGT-HGKTFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLSDQREVNERQAKELADKYGIPYFETSAASGQDVEKSVDTLLDLIMKRMEQCVDKTQVPD 286

[Close]

BLAST of Ras-related protein Rab-27B vs. Ensembl Xenopus
Match: rab27a (RAB27A, member RAS oncogene family [Source:NCBI gene;Acc:493339])

HSP 1 Score: 216.853 bits (551), Expect = 6.505e-71
Identity = 106/186 (56.99%), Postives = 143/186 (76.88%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +YDYLI+ LALGD  VGKT+FLY YTD KF+  F +T+G+DFR+KR+++RS +  D   G  Q +HLQLWDTAGQERFRSL + FFRDAMGF+L+FDLTNE+S LNVR WM+ L+ +AYC+NPDI+L GNK DL   R V EE AK+ A+++ +PY ETS   G  V +A++ L++++M R+E ++
Sbjct:    5 DYDYLIKFLALGDSGVGKTSFLYQYTDAKFNSKFITTVGIDFREKRVVYRS-NGPDGISGRGQRVHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWMSQLQVHAYCENPDIVLCGNKCDLDEQRAVKEEEAKEFAEKYGIPYFETSAAIGTNVNKAVETLLDLIMKRMERNL 189

[Close]

BLAST of Ras-related protein Rab-27B vs. Ensembl Xenopus
Match: rab27a (RAB27A, member RAS oncogene family [Source:NCBI gene;Acc:493339])

HSP 1 Score: 216.853 bits (551), Expect = 1.528e-70
Identity = 106/186 (56.99%), Postives = 142/186 (76.34%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +YDYLI+ LALGD  VGKT+FLY YTD KF+  F +T+G+DFR+KR+++RS +  D   G  Q +HLQLWDTAGQERFRSL + FFRDAMGF+L+FDLTNE+S LNVR WM+ L+ +AYC+NPDI+L GNK DL   R V EE AK+ A+++ +PY ETS   G  V +A++ L++++M R+E  +
Sbjct:    5 DYDYLIKFLALGDSGVGKTSFLYQYTDAKFNSKFITTVGIDFREKRVVYRS-NGPDGISGRGQRVHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWMSQLQVHAYCENPDIVLCGNKCDLDEQRAVKEEEAKEFAEKYGIPYFETSAAIGTNVNKAVETLLDLIMKRMERCV 189

[Close]

BLAST of Ras-related protein Rab-27B vs. Ensembl Xenopus
Match: rab27a (RAB27A, member RAS oncogene family [Source:NCBI gene;Acc:493339])

HSP 1 Score: 150.599 bits (379), Expect = 6.948e-45
Identity = 86/188 (45.74%), Postives = 123/188 (65.43%), Query Frame = 3

Query:   54 NDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            + +YDYLI+ LALGD  VGKT+FLY YTD KF+  F +T+G+DFR+KR+++RS +  D   G  Q +HLQLWDTAGQER     S  F   +   L+       SL+ V  ++  L+ +AYC+NPDI+L GNK DL   R V EE AK+ A+++ +PY ETS   G  V +A++ L++++M R+E  +
Sbjct:    3 DGDYDYLIKFLALGDSGVGKTSFLYQYTDAKFNSKFITTVGIDFREKRVVYRS-NGPDGISGRGQRVHLQLWDTAGQERH----SFPFHCCISDKLL-------SLITV--FIGQLQVHAYCENPDIVLCGNKCDLDEQRAVKEEEAKEFAEKYGIPYFETSAAIGTNVNKAVETLLDLIMKRMERCV 176

[Close]

BLAST of Ras-related protein Rab-27B vs. Ensembl Mouse
Match: Rab27b (RAB27B, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1931295])

HSP 1 Score: 237.654 bits (605), Expect = 6.708e-79
Identity = 107/193 (55.44%), Postives = 149/193 (77.20%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITN 632
            +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+++      D   G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+L+GNKADLP  R V E  A+++A+++ +PY ETS   G  VE++++ L++++M R+E  +   ++ +
Sbjct:    5 DYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVY-DTQGADGASGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELAEKYGIPYFETSAATGQNVEKSVETLLDLIMKRMEKCVEKTQVPD 196

[Close]

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITN 632
            +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+++      D   G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+L+GNKADLP  R V E  A+++A+++ +PY ETS   G  VE++++ L++++M R+E  +   ++ +
Sbjct:    5 DYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVY-DTQGADGASGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELAEKYGIPYFETSAATGQNVEKSVETLLDLIMKRMEKCVEKTQVPD 196

[Close]

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITN 632
            +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+++      D   G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+L+GNKADLP  R V E  A+++A+++ +PY ETS   G  VE++++ L++++M R+E  +   ++ +
Sbjct:    5 DYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVY-DTQGADGASGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELAEKYGIPYFETSAATGQNVEKSVETLLDLIMKRMEKCVEKTQVPD 196

[Close]

BLAST of Ras-related protein Rab-27B vs. Ensembl Mouse
Match: Rab27a (RAB27A, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1861441])

HSP 1 Score: 230.72 bits (587), Expect = 3.600e-76
Identity = 103/186 (55.38%), Postives = 145/186 (77.96%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +YDYLI+ LALGD  VGKT+ LY YTDGKF+  F +T+G+DFR+KR+++R+ +  D  +G  Q +HLQLWDTAGQERFRSL + FFRDAMGF+L+FDLTNE+S LNVR W++ L+ +AYC+NPDI+L GNK+DL   R V EE A+++A+++ +PY ETS  NG  +  A++ L++++M R+E  +
Sbjct:    5 DYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRA-NGPDGAVGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRAVKEEEARELAEKYGIPYFETSAANGTNISHAIEMLLDLIMKRMERCV 189

[Close]

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +YDYLI+ LALGD  VGKT+ LY YTDGKF+  F +T+G+DFR+KR+++R+ +  D  +G  Q +HLQLWDTAGQERFRSL + FFRDAMGF+L+FDLTNE+S LNVR W++ L+ +AYC+NPDI+L GNK+DL   R V EE A+++A+++ +PY ETS  NG  +  A++ L++++M R+E  +
Sbjct:    5 DYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRA-NGPDGAVGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRAVKEEEARELAEKYGIPYFETSAANGTNISHAIEMLLDLIMKRMERCV 189

[Close]

BLAST of Ras-related protein Rab-27B vs. UniProt/SwissProt
Match: sp|Q99P58|RB27B_MOUSE (Ras-related protein Rab-27B OS=Mus musculus OX=10090 GN=Rab27b PE=1 SV=3)

HSP 1 Score: 237.654 bits (605), Expect = 4.693e-78
Identity = 107/193 (55.44%), Postives = 149/193 (77.20%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITN 632
            +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+++      D   G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+L+GNKADLP  R V E  A+++A+++ +PY ETS   G  VE++++ L++++M R+E  +   ++ +
Sbjct:    5 DYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVY-DTQGADGASGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELAEKYGIPYFETSAATGQNVEKSVETLLDLIMKRMEKCVEKTQVPD 196

[Close]

BLAST of Ras-related protein Rab-27B vs. UniProt/SwissProt
Match: sp|O00194|RB27B_HUMAN (Ras-related protein Rab-27B OS=Homo sapiens OX=9606 GN=RAB27B PE=1 SV=4)

HSP 1 Score: 236.884 bits (603), Expect = 8.838e-78
Identity = 109/193 (56.48%), Postives = 149/193 (77.20%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITN 632
            +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+++ +     S  G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+L+GNKADLP  R V E  A+++A ++ +PY ETS   G  VE+A++ L++++M R+E  +   +I +
Sbjct:    5 DYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYNAQGPNGSS-GKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELADKYGIPYFETSAATGQNVEKAVETLLDLIMKRMEQCVEKTQIPD 196

[Close]

BLAST of Ras-related protein Rab-27B vs. UniProt/SwissProt
Match: sp|Q8HZJ5|RB27B_BOVIN (Ras-related protein Rab-27B OS=Bos taurus OX=9913 GN=RAB27B PE=2 SV=3)

HSP 1 Score: 234.572 bits (597), Expect = 6.166e-77
Identity = 108/191 (56.54%), Postives = 147/191 (76.96%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKI 626
            +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+ + +    +   G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+L+GNKADLP  R V E  A+ +A+++++PY ETS   G  VE+A++ L++++M R+E  +    I
Sbjct:    5 DYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVAY-NTQGPNGPTGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARDLAEKYSIPYFETSAATGQNVEKAVETLLDLIMKRMEQCVEKTHI 194

[Close]

BLAST of Ras-related protein Rab-27B vs. UniProt/SwissProt
Match: sp|Q99P74|RB27B_RAT (Ras-related protein Rab-27B OS=Rattus norvegicus OX=10116 GN=Rab27b PE=2 SV=3)

HSP 1 Score: 233.802 bits (595), Expect = 1.383e-76
Identity = 106/198 (53.54%), Postives = 150/198 (75.76%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITNPSHTI 647
            +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+++      D   G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+L+GNKADL   R V E  A+++A+++ +PY ETS   G  VE++++ L++++M R+E  +   ++ +  + +
Sbjct:    5 DYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVY-DTQGADGSSGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLLDQREVNERQARELAEKYGIPYFETSAATGQNVEKSVETLLDLIMKRMEKCVEKTQVPDTVNGV 201

[Close]

BLAST of Ras-related protein Rab-27B vs. UniProt/SwissProt
Match: sp|P23640|RB27A_RAT (Ras-related protein Rab-27A OS=Rattus norvegicus OX=10116 GN=Rab27a PE=1 SV=1)

HSP 1 Score: 230.72 bits (587), Expect = 2.025e-75
Identity = 103/186 (55.38%), Postives = 146/186 (78.49%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +YDYLI+ LALGD  VGKT+ LY YTDGKF+  F +T+G+DFR+KR+++R+ +  D  +G  Q +HLQLWDTAGQERFRSL + FFRDAMGF+L+FDLTNE+S LNVR W++ L+ +AYC+NPDI+L GNK+DL   R V EE A+++A+++ +PY ETS  NG  + +A++ L++++M R+E  +
Sbjct:    5 DYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRA-NGPDGTVGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRAVKEEEARELAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRMERCV 189

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BLAST of Ras-related protein Rab-27B vs. TrEMBL
Match: Q5BYA6 (SJCHGC04801 protein (Fragment) OS=Schistosoma japonicum OX=6182 PE=2 SV=2)

HSP 1 Score: 252.677 bits (644), Expect = 1.408e-81
Identity = 119/195 (61.03%), Postives = 154/195 (78.97%), Query Frame = 3

Query:   48 ARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKI 626
            A +DEYDYLI+LLALGD +VGKT+ LY YTD  F+P FT+T+GVDFRQKR++  S D ++  LG +Q LHLQLWDTAGQER+RSLC++F RDAMGF+L+FDLTNE SL + REWMN+L  +AYCD PD++LVGNK DL   R V+  AA  +A+E ++PYIETS   G +V  A+D+L+++VMTRIE S+T  +I
Sbjct:    3 APDDEYDYLIKLLALGDSNVGKTSLLYQYTDNIFNPRFTTTVGVDFRQKRLVRESRD-SEGLLGPKQRLHLQLWDTAGQERYRSLCTVFLRDAMGFLLVFDLTNESSLQSCREWMNLLCQHAYCDRPDVVLVGNKFDLTKERQVSMSAANAMARELDVPYIETSAATGYQVTAAVDRLLDLVMTRIEASVTKARI 196

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BLAST of Ras-related protein Rab-27B vs. TrEMBL
Match: C1L3U1 (Rab-protein 8 OS=Schistosoma japonicum OX=6182 GN=Rab8 PE=2 SV=1)

HSP 1 Score: 252.677 bits (644), Expect = 2.096e-81
Identity = 119/195 (61.03%), Postives = 154/195 (78.97%), Query Frame = 3

Query:   48 ARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKI 626
            A +DEYDYLI+LLALGD +VGKT+ LY YTD  F+P FT+T+GVDFRQKR++  S D ++  LG +Q LHLQLWDTAGQER+RSLC++F RDAMGF+L+FDLTNE SL + REWMN+L  +AYCD PD++LVGNK DL   R V+  AA  +A+E ++PYIETS   G +V  A+D+L+++VMTRIE S+T  +I
Sbjct:   12 APDDEYDYLIKLLALGDSNVGKTSLLYQYTDNIFNPRFTTTVGVDFRQKRLVRESRD-SEGLLGPKQRLHLQLWDTAGQERYRSLCTVFLRDAMGFLLVFDLTNESSLQSCREWMNLLCQHAYCDRPDVVLVGNKFDLTKERQVSMSAANAMARELDVPYIETSAATGYQVTAAVDRLLDLVMTRIEASVTKARI 205

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BLAST of Ras-related protein Rab-27B vs. TrEMBL
Match: A0A095AT55 (Ras-related protein Rab-27B OS=Schistosoma haematobium OX=6185 GN=MS3_05976 PE=4 SV=1)

HSP 1 Score: 250.366 bits (638), Expect = 1.417e-80
Identity = 119/195 (61.03%), Postives = 152/195 (77.95%), Query Frame = 3

Query:   48 ARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKI 626
            A +DEYDYLI+LLALGD +VGKT+ LY YTD  F+P FT+T+GVDFRQKR++  S D ++  LG +Q LHLQLWDTAGQER+RSLC++F RDAMGF+L+FDLTNE S  N   WMN+L  NAYCD PD++LVGNK DL   R V+  AAK +A + N+PYIETS   G +V +A+D+L+++VMTRIE S+T  +I
Sbjct:   12 APDDEYDYLIKLLALGDSNVGKTSLLYQYTDNIFNPRFTTTVGVDFRQKRLVRESRD-SEGLLGPKQRLHLQLWDTAGQERYRSLCTVFLRDAMGFLLVFDLTNENSFKNCHAWMNLLCDNAYCDRPDVVLVGNKFDLTSERQVSMSAAKAMACDLNVPYIETSAATGYQVNDAVDRLLDLVMTRIEASVTKARI 205

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BLAST of Ras-related protein Rab-27B vs. TrEMBL
Match: A0A183NVF6 (Uncharacterized protein OS=Schistosoma mattheei OX=31246 GN=SMTD_LOCUS6092 PE=4 SV=1)

HSP 1 Score: 250.366 bits (638), Expect = 1.496e-80
Identity = 119/195 (61.03%), Postives = 152/195 (77.95%), Query Frame = 3

Query:   48 ARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKI 626
            A +DEYDYLI+LLALGD +VGKT+ LY YTD  F+P FT+T+GVDFRQKR++  S D ++  LG +Q LHLQLWDTAGQER+RSLC++F RDAMGF+L+FDLTNE S  N   WMN+L  NAYCD PD++LVGNK DL   R V+  AAK +A + N+PYIETS   G +V +A+D+L+++VMTRIE S+T  +I
Sbjct:   12 APDDEYDYLIKLLALGDSNVGKTSLLYQYTDNIFNPRFTTTVGVDFRQKRLVRESRD-SEGLLGPKQRLHLQLWDTAGQERYRSLCTVFLRDAMGFLLVFDLTNENSFKNCHAWMNLLCDNAYCDRPDVVLVGNKFDLTSERQVSMSAAKAMACDLNVPYIETSAATGYQVNDAVDRLLDLVMTRIEASVTKARI 205

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BLAST of Ras-related protein Rab-27B vs. TrEMBL
Match: A0A3Q0KN12 (Putative rab OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 250.366 bits (638), Expect = 1.546e-80
Identity = 119/195 (61.03%), Postives = 152/195 (77.95%), Query Frame = 3

Query:   48 ARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKI 626
            A +DEYDYLI+LLALGD +VGKT+ LY YTD  F+P FT+T+GVDFRQKR++  S D ++  LG +Q LHLQLWDTAGQER+RSLC++F RDAMGF+L+FDLTNE S  N   WMN+L  NAYCD PD++LVGNK DL   R V+  AAK +A + N+PYIETS   G +V +A+D+L+++VMTRIE S+T  +I
Sbjct:   12 APDDEYDYLIKLLALGDSNVGKTSLLYQYTDNIFNPRFTTTVGVDFRQKRLVRESRD-SEGLLGPKQRLHLQLWDTAGQERYRSLCTVFLRDAMGFLLVFDLTNENSFKNCHAWMNLLCDNAYCDRPDVVLVGNKFDLTSERQVSMSAAKAMACDLNVPYIETSAATGYQVNDAVDRLLDLVMTRIEASVTKARI 205

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BLAST of Ras-related protein Rab-27B vs. Ensembl Cavefish
Match: rab27b (RAB27B, member RAS oncogene family [Source:NCBI gene;Acc:103022885])

HSP 1 Score: 237.269 bits (604), Expect = 6.845e-79
Identity = 109/186 (58.60%), Postives = 147/186 (79.03%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+++ S +  +   G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+LVGNKADL   R V E+ AK++A ++ +PY ETS   G +V++A+  L+++VM R+E  +
Sbjct:    5 DYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVY-STNSPNGTTGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLVGNKADLADQREVQEKQAKELADKYGIPYFETSAATGAQVDKAVVTLLDLVMKRMEQCV 189

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BLAST of Ras-related protein Rab-27B vs. Ensembl Cavefish
Match: rab27a (RAB27A, member RAS oncogene family [Source:NCBI gene;Acc:103047190])

HSP 1 Score: 229.565 bits (584), Expect = 6.839e-76
Identity = 104/186 (55.91%), Postives = 144/186 (77.42%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +YDYLI+ LALGD  VGKT+FLY YTDGKF+  F +T+G+DFR+KR++++S    D   G  Q +H+QLWDTAGQERFRSL + FFRDAMGF+L+FDL+NE+S LNVR WM+ L+ +AYC+NPDI+L GNK DL   R V+EE A+++A+++ +PY ETS  NG  V  A++ L++++M R+E  +
Sbjct:    5 DYDYLIKFLALGDSGVGKTSFLYQYTDGKFNSKFITTVGIDFREKRVVYKS-SGPDGTPGRGQRIHIQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLSNEQSFLNVRNWMSQLQMHAYCENPDIVLCGNKCDLEDQRAVSEEEARELAEKYGIPYFETSAANGENVSRAVEVLLDLIMKRMERCV 189

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Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +YDYLI+ LALGD  VGKT+FLY YTDGKF+  F +T+G+DFR+KR++++S    D   G  Q +H+QLWDTAGQERFRSL + FFRDAMGF+L+FDL+NE+S LNVR WM+ L+ +AYC+NPDI+L GNK DL   R V+EE A+++A+++ +PY ETS  NG  V  A++ L++++M R+E  +
Sbjct:    5 DYDYLIKFLALGDSGVGKTSFLYQYTDGKFNSKFITTVGIDFREKRVVYKS-SGPDGTPGRGQRIHIQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLSNEQSFLNVRNWMSQLQMHAYCENPDIVLCGNKCDLEDQRAVSEEEARELAEKYGIPYFETSAANGENVSRAVEVLLDLIMKRMERCV 189

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BLAST of Ras-related protein Rab-27B vs. Ensembl Cavefish
Match: rab3ab (RAB3A, member RAS oncogene family [Source:NCBI gene;Acc:103043849])

HSP 1 Score: 148.673 bits (374), Expect = 3.538e-44
Identity = 67/185 (36.22%), Postives = 116/185 (62.70%), Query Frame = 3

Query:   63 YDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +DY+ ++L +G+  VGKT+FL+ Y D  F P F ST+G+DF+ K I              ++ + LQ+WDTAGQER+R++ + ++R AMGF+LM+D+TNEES   V++W   +K  ++ DN  ++LVGNK D+   R V  E  +++++     + E S  + I V++  ++LV+++  ++  S+
Sbjct:   19 FDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRN-----------DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFAAVQDWSTQIKTYSW-DNAQVLLVGNKCDMEDERVVAAERGRQLSEHLGFEFFEASAKDNINVKQTFERLVDIICEKMSESL 191

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Query:   63 YDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +DY+ ++L +G+  VGKT+FL+ Y D  F P F ST+G+DF+ K I              ++ + LQ+WDTAGQER+R++ + ++R AMGF+LM+D+TNEES   V++W   +K  ++ DN  ++LVGNK D+   R V  E  +++++     + E S  + I V++  ++LV+++  ++  S+
Sbjct:   19 FDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRN-----------DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFAAVQDWSTQIKTYSW-DNAQVLLVGNKCDMEDERVVAAERGRQLSEHLGFEFFEASAKDNINVKQTFERLVDIICEKMSESL 191

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BLAST of Ras-related protein Rab-27B vs. Ensembl Sea Lamprey
Match: rab27a (RAB27A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-050913-46])

HSP 1 Score: 201.83 bits (512), Expect = 1.227e-65
Identity = 92/185 (49.73%), Postives = 136/185 (73.51%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP-RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            EYDYLI+LL LGD  VGK++ L  YT+G+F   + +T+G+DFR+KR+ + + +  D    + + +HLQLWDTAGQERFRSL + FFRDAMGF+++FDLT+E++ LNVR W+N L+ +AYC++PDI+L GNK+DL    +T++ AK+ A++  +PY ETS   G  V  A++ L+ ++M R+E  I
Sbjct:    5 EYDYLIKLLVLGDSGVGKSSLLCQYTEGRFHDKYITTVGIDFREKRVTYTN-EGADGTAKQTKRVHLQLWDTAGQERFRSLTTAFFRDAMGFLVIFDLTSEQTFLNVRNWLNQLQMHAYCESPDIVLCGNKSDLSEHNITQKQAKEFAEKHGMPYFETSARTGNNVVPAVETLLGLIMKRMERCI 188

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BLAST of Ras-related protein Rab-27B vs. Ensembl Sea Lamprey
Match: rab27a (RAB27A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-050913-46])

HSP 1 Score: 160.614 bits (405), Expect = 9.414e-51
Identity = 73/114 (64.04%), Postives = 93/114 (81.58%), Query Frame = 3

Query:   54 NDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMN 395
            + +YD+LI+LLALGD  VGKT+ LY YTDGKF+  F +T+G+DFR+KR+++RS +  D   G  Q +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+E+S LNVR WM+
Sbjct:   16 DSDYDFLIKLLALGDSGVGKTSLLYNYTDGKFNSKFVTTVGIDFREKRVVYRS-ENADGITGRGQRVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSEQSFLNVRNWMS 128

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BLAST of Ras-related protein Rab-27B vs. Ensembl Sea Lamprey
Match: rab3c (RAB3C, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-040718-263])

HSP 1 Score: 149.058 bits (375), Expect = 7.713e-45
Identity = 69/190 (36.32%), Postives = 118/190 (62.11%), Query Frame = 3

Query:   48 ARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            A +  +DY+ +LL +G+  VGKT+FL+ Y D  F   F ST+G+DF+ K +              E+ + LQ+WDTAGQER+R++ + ++R AMGF+LM+D+TNE+S   V +W   +K  ++ DN  ++LVGNK D+   R V  E  +++A++    + ETS  + I V++  ++LV+++  ++  S+
Sbjct:   21 AADQNFDYMFKLLIIGNSSVGKTSFLFRYADESFTSAFVSTVGIDFKVKTVYR-----------NEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEDSFNAVSDWSTQIKTYSW-DNAQVVLVGNKCDMEDDRMVPTEQGRQLAEQLGFEFFETSAKDNINVKQTFERLVDVICEKMSESL 198

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BLAST of Ras-related protein Rab-27B vs. Ensembl Sea Lamprey
Match: rab27a (RAB27A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-050913-46])

HSP 1 Score: 142.124 bits (357), Expect = 8.087e-43
Identity = 65/124 (52.42%), Postives = 89/124 (71.77%), Query Frame = 3

Query:  237 GEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIE 602
            G+   +HLQLWDTAGQ RFRSL + FFRDAMGF + FD+T+E+S +NVR WM +L+ +AYC +PD++L GNKADL   R V E+ A  +A E+ +PY+ETS   G  V  A++ L+  VM R++
Sbjct:   12 GDGLKIHLQLWDTAGQRRFRSLTNAFFRDAMGFFVFFDITDEQSFVNVRHWMVVLQHHAYCPSPDVVLCGNKADLTEQRAVGEDDALSLASEYGMPYVETSAATGENVARAVELLLERVMRRVQ 135

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BLAST of Ras-related protein Rab-27B vs. Ensembl Sea Lamprey
Match: rab8a (RAB8A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-070424-36])

HSP 1 Score: 135.961 bits (341), Expect = 5.289e-40
Identity = 75/203 (36.95%), Postives = 120/203 (59.11%), Query Frame = 3

Query:   63 YDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITN--------YKITNPSH 641
            YDYL +LL +GD  VGKT  L+ +++  F+  F STIG+DF+      R++D       + + + LQ+WDTAGQERFR++ + ++R AMG +L++D+TNE+S  N++ W+  ++ +A  D   +IL GNK D+   R VT E  +K+A E+ + ++ETS    I VEEA   L   +  +++  +           +IT PS 
Sbjct:    5 YDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFK-----IRTIDL------DGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFENIKNWIRNIEEHASADVEKMIL-GNKCDMNERRQVTRERGEKLAIEYGIKFMETSAKASINVEEAFFTLARDIKAKMDRKLEGNNTPDSNAVRITAPSQ 195

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BLAST of Ras-related protein Rab-27B vs. Ensembl Yeast
Match: SEC4 (Rab family GTPase; essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane [Source:SGD;Acc:S000001889])

HSP 1 Score: 133.65 bits (335), Expect = 2.766e-39
Identity = 66/183 (36.07%), Postives = 114/183 (62.30%), Query Frame = 3

Query:   63 YDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL-PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENS 608
            YD ++++L +GD  VGK+  L  + + KF+P F +TIG+DF+ K     +VD         + + LQLWDTAGQERFR++ + ++R AMG +L++D+T+E +  N+++W   +  +A  D   ++LVGNK+D+  R VT +  + +A+E  +P+IE+S  N   V E    L  ++  +I+++
Sbjct:   17 YDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIK-----TVDING------KKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHAN-DEAQLLLVGNKSDMETRVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDSN 187

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BLAST of Ras-related protein Rab-27B vs. Ensembl Yeast
Match: YPT31 (Rab family GTPase; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; YPT31 has a paralog, YPT32, that arose from the whole genome duplication; localizes to the transitional and late Golgi [Source:SGD;Acc:S000000833])

HSP 1 Score: 119.013 bits (297), Expect = 1.508e-33
Identity = 64/182 (35.16%), Postives = 108/182 (59.34%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRI 599
            +YD L +++ +GD  VGK+  L  +T  +F+    STIGV+F  + +    +D         + +  Q+WDTAGQER+R++ S ++R A+G ++++D++   S  N   W++ L+ NA  DN  + L+GNK+DL   R V  E +K  AQE  L + ETS LN   V++A ++L+N +  ++
Sbjct:    9 DYDLLFKIVLIGDSGVGKSNLLSRFTKNEFNMDSKSTIGVEFATRTL---EIDG--------KRIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLSELRENAD-DNVAVGLIGNKSDLAHLRAVPTEESKTFAQENQLLFTETSALNSENVDKAFEELINTIYQKV 178

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BLAST of Ras-related protein Rab-27B vs. Ensembl Yeast
Match: YPT1 (Rab family GTPase; involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by type II protein geranylgeranyltransferase (Bet2p-Bet4p); binds to unspliced HAC1 mRNA; regulates the unfolded protein response (UPR) by promoting the decay of HAC1 RNA; localizes to the early Golgi, the transitional Golgi and ER membranes, pre-autophagosomal structures, and cytoplasmic vesicles [Source:SGD;Acc:S000001856])

HSP 1 Score: 117.857 bits (294), Expect = 2.607e-33
Identity = 64/173 (36.99%), Postives = 104/173 (60.12%), Query Frame = 3

Query:   54 NDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDI-ILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEA 563
            N EYDYL +LL +G+  VGK+  L  ++D  +   + STIGVDF+ K +             + + + LQ+WDTAGQERFR++ S ++R + G ++++D+T++ES   V+ W+   + + Y  +  + +LVGNK DL   R V  + AK+ A    +P++ETS L+   VE+A
Sbjct:    2 NSEYDYLFKLLLIGNSGVGKSCLLLRFSDDTYTNDYISTIGVDFKIKTVEL-----------DGKTVKLQIWDTAGQERFRTITSSYYRGSHGIIIVYDVTDQESFNGVKMWLQ--EIDRYATSTVLKLLVGNKCDLKDKRVVEYDVAKEFADANKMPFLETSALDSTNVEDA 161

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BLAST of Ras-related protein Rab-27B vs. Ensembl Yeast
Match: YPT32 (Rab family GTPase involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; protein abundance increases in response to DNA replication stress; YPT32 has a paralog, YPT31, that arose from the whole genome duplication [Source:SGD;Acc:S000003178])

HSP 1 Score: 113.62 bits (283), Expect = 1.775e-31
Identity = 63/175 (36.00%), Postives = 101/175 (57.71%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLV 578
            +YDYL +++ +GD  VGK+  L  +T  +F+    STIGV+F  + I             E + +  Q+WDTAGQER+R++ S ++R A+G ++++D++   S  N   W+  L+ NA  DN  + L+GNK+DL   R V  + AK  A E  + + ETS LN   V++A  +L+
Sbjct:    9 DYDYLFKIVLIGDSGVGKSNLLSRFTTDEFNIESKSTIGVEFATRTIEV-----------ENKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLTELRENA-DDNVAVGLIGNKSDLAHLRAVPTDEAKNFAMENQMLFTETSALNSDNVDKAFRELI 171

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BLAST of Ras-related protein Rab-27B vs. Ensembl Yeast
Match: YPT7 (Rab family GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion; localizes to sites of contact between the vacuole and mitochondria (vCLAMPs); interacts with the cargo selection/retromer complex for retrograde sorting; similar to mammalian Rab7 [Source:SGD;Acc:S000004460])

HSP 1 Score: 105.531 bits (262), Expect = 1.603e-28
Identity = 57/182 (31.32%), Postives = 107/182 (58.79%), Query Frame = 3

Query:   72 LIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPD---IILVGNKADL---PRTVTEEAAKKVAQEF-NLPYIETSGLNGIRVEEAMDKLVNMVMTR 596
            +++++ LGD  VGKT+ ++ Y + K+   + +TIG DF  K +   +VD        +++  +Q+WDTAGQERF+SL   F+R A   VL++D+TN  S  N++ W +    +A  ++P+    +++GNK D     + V+E++A+++A+   ++P   TS  N I V+ A +++    + +
Sbjct:    8 ILKVIILGDSGVGKTSLMHRYVNDKYSQQYKATIGADFLTKEV---TVDG-------DKVATMQVWDTAGQERFQSLGVAFYRGADCCVLVYDVTNASSFENIKSWRDEFLVHANVNSPETFPFVILGNKIDAEESKKIVSEKSAQELAKSLGDIPLFLTSAKNAINVDTAFEEIARSALQQ 179

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BLAST of Ras-related protein Rab-27B vs. Ensembl Nematostella
Match: EDO49958 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RER3])

HSP 1 Score: 216.468 bits (550), Expect = 4.840e-71
Identity = 100/193 (51.81%), Postives = 137/193 (70.98%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITN 632
            +YDYLI+ LALGD  VGKT+ LY YTD  F+P F ST+G+DFR+KR++H  ++         Q +HLQLWDTAGQERFRSL + FFRDAMGF+L+FDLT+E+S +N+R W++ L+ +AYC+NPDI+L+GNKADL   R V E  A+ +A    L Y ETS   G  V ++++ L++ VM R+EN +    + N
Sbjct:    7 DYDYLIKFLALGDSGVGKTSILYQYTDESFNPKFISTVGIDFREKRVVHHPLNPDGERSTRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLVFDLTHEQSFVNIRNWLSQLQTHAYCENPDIVLLGNKADLEDDRVVDEAEARALADNLGLKYFETSAATGQNVTKSVEALLDQVMVRMENCVDRATLPN 199

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BLAST of Ras-related protein Rab-27B vs. Ensembl Nematostella
Match: EDO28309 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6U5])

HSP 1 Score: 205.682 bits (522), Expect = 2.159e-67
Identity = 95/178 (53.37%), Postives = 129/178 (72.47%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMV 587
            +YDYLI+ LALGD  VGKT+ LY YTD  F+P F ST+G+DFR+KR++H  ++         Q +HLQLWDTAGQERFRSL + FFRDAMGF+L+FDLT+E+S +N+R W++ L+ +AYC+NPDI+L+GNKADL   R V E  A+ +A    L Y ETS   G  V ++++ L++ V
Sbjct:    7 DYDYLIKFLALGDSGVGKTSILYQYTDESFNPKFISTVGIDFREKRVVHHPLNPDGERSTRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLVFDLTHEQSFVNIRNWLSQLQTHAYCENPDIVLLGNKADLEDDRVVDEAEARALADNLGLKYFETSAATGQNVTKSVEALLDQV 184

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BLAST of Ras-related protein Rab-27B vs. Ensembl Nematostella
Match: EDO34944 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMW8])

HSP 1 Score: 146.362 bits (368), Expect = 1.100e-43
Identity = 69/190 (36.32%), Postives = 118/190 (62.11%), Query Frame = 3

Query:   48 ARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            A +  +DY+ +LL +G+  VGKT+FL+ Y D  F   F ST+G+DF+ K +              ++ + LQ+WDTAGQER+R++ + ++R AMGF+LM+D+TNEES   V++W   +K  ++  N  +ILVGNK D+   R V+ +  K++A +  L + ETS  +   V++  ++LV+++  ++  S+
Sbjct:   13 AADQNFDYMFKLLIIGNSAVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFR-----------NDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFQAVQDWSTQVKTYSWA-NAQVILVGNKCDMEEERVVSYDRGKQLADQLGLEFYETSAKDNTNVKKVFERLVDIICDKMSQSL 190

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BLAST of Ras-related protein Rab-27B vs. Ensembl Nematostella
Match: EDO41018 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5I6])

HSP 1 Score: 132.88 bits (333), Expect = 1.305e-38
Identity = 70/196 (35.71%), Postives = 121/196 (61.73%), Query Frame = 3

Query:   63 YDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITNPSHT 644
            YD+L +LL +GD  VGKT  L+ +++  F+  F STIG+DF+ + I    +D         + + LQ+WDTAGQERFR++ + ++R AMG +L++D+TN++S  N++ W+  ++ +A  D   ++L GNK D+   R V++E  +++A E+ + ++ETS    I VEEA   L   +  +++  + N   +NP+ T
Sbjct:    5 YDFLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTI---ELDG--------KKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNDKSFENIKNWIRNIEEHASQDVEKMVL-GNKCDMEDRRQVSKERGEQLAVEYGIKFMETSAKASINVEEAFFTLARDIKLKMDKKLEN---SNPAST 185

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BLAST of Ras-related protein Rab-27B vs. Ensembl Nematostella
Match: EDO40167 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S806])

HSP 1 Score: 132.494 bits (332), Expect = 1.492e-38
Identity = 71/187 (37.97%), Postives = 111/187 (59.36%), Query Frame = 3

Query:   54 NDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENS 608
            N EYDYL +LL +GD  VGK+  L  + D  +   + STIGVDF+ + I    +D         + + LQ+WDTAGQERFR++ S ++R A G ++++D+T++ES  NV++W+  +   A C+N + +LVGNK DL   + V    AK+ A+   +P++ETS  N   VE+A   +   +  R+  S
Sbjct:    5 NPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTI---ELDG--------KTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYA-CENVNKLLVGNKCDLTTKKVVDFTTAKEYAESLGVPFLETSAKNATNVEQAFMTMAAEIKNRMGPS 179

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BLAST of Ras-related protein Rab-27B vs. Ensembl Medaka
Match: rab27b (RAB27B, member RAS oncogene family [Source:NCBI gene;Acc:101161176])

HSP 1 Score: 235.343 bits (599), Expect = 3.900e-78
Identity = 107/186 (57.53%), Postives = 145/186 (77.96%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            +YDYLI+LLALGD  VGKTTFLY YTD KF+P F +T+G+DFR+KR+++ + +   +  G+   +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLT+++S LNVR WM+ L+ANAYC+NPDI+LVGNK DL   R V E+ AK++A ++ +PY ETS   G  V++A+  L+++VM R+E  +
Sbjct:    5 DYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYTASNPNGTTTGKTFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLVGNKVDLADQREVQEKQAKELADKYGIPYFETSAATGAEVDKAVITLLDLVMKRMEQCV 190

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BLAST of Ras-related protein Rab-27B vs. Ensembl Medaka
Match: rab27a (RAB27A, member RAS oncogene family [Source:NCBI gene;Acc:101164788])

HSP 1 Score: 220.32 bits (560), Expect = 3.749e-72
Identity = 101/186 (54.30%), Postives = 141/186 (75.81%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            EYDYLI+ LALGD  VGKT+FLY YTDGKF+  F +T+G+DFR+K ++        +   + Q +HLQLWDTAGQERFRSL + FFRDAMGF+L+FDLTNE+S LNVR WM+ L+ +AYC+NPD++L GNK DL   R ++E+ A+++A+++ +PY ETS  NG  V EA+  L++++M R+E+ +
Sbjct:    5 EYDYLIKFLALGDSGVGKTSFLYQYTDGKFNSKFITTVGIDFREKTVLFPPTGSGGTS-SKGQKIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWMSQLQMHAYCENPDVVLCGNKCDLMDQRAISEDEARELAEKYGIPYFETSAANGQNVTEAVRILLDLIMRRMEHCV 189

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BLAST of Ras-related protein Rab-27B vs. Ensembl Medaka
Match: ENSORLT00000000515.2 (ras-related protein Rab-27B [Source:NCBI gene;Acc:101172416])

HSP 1 Score: 222.631 bits (566), Expect = 4.755e-70
Identity = 107/198 (54.04%), Postives = 142/198 (71.72%), Query Frame = 3

Query:   60 EYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITNPSHTI 647
            +YDYLI+LLALGD   GKTTFL+ YTD KF   FT+T+G+DFR+KR+++      D        +HLQLWDTAGQERFRSL + FFRDAMGF+LMFDLTN++S +NVR WM+ L+ANAYCD+PD++LVG KADL   R V    A+++A+ + +PY ETS L G  V++A+  L+N+VM R+E      +  N SH+ 
Sbjct:  257 DYDYLIKLLALGDSGAGKTTFLHRYTDNKFHRRFTTTVGIDFREKRVVYVGTG-ADGASERSFRVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTNQQSFVNVRNWMSQLQANAYCDSPDVVLVGTKADLKDMRNVHARQARELAERYGIPYFETSALTGAGVDQAVTTLLNLVMKRMEQGAYGSE-PNGSHSC 452

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BLAST of Ras-related protein Rab-27B vs. Ensembl Medaka
Match: rab27a (RAB27A, member RAS oncogene family [Source:NCBI gene;Acc:101164788])

HSP 1 Score: 191.43 bits (485), Expect = 7.001e-61
Identity = 87/155 (56.13%), Postives = 119/155 (76.77%), Query Frame = 3

Query:   54 NDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFN 512
            + EYDYLI+ LALGD  VGKT+FLY YTDGKF+  F +T+G+DFR+K ++        +   + Q +HLQLWDTAGQERFRSL + FFRDAMGF+L+FDLTNE+S LNVR WM+ L+ +AYC+NPD++L GNK DL   R ++E+ A+++A+++ 
Sbjct:    3 DGEYDYLIKFLALGDSGVGKTSFLYQYTDGKFNSKFITTVGIDFREKTVLFPPTGSGGTS-SKGQKIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWMSQLQMHAYCENPDVVLCGNKCDLMDQRAISEDEARELAEKYG 156

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BLAST of Ras-related protein Rab-27B vs. Ensembl Medaka
Match: rab3c (RAB3C, member RAS oncogene family [Source:NCBI gene;Acc:101166306])

HSP 1 Score: 147.902 bits (372), Expect = 7.593e-44
Identity = 71/200 (35.50%), Postives = 124/200 (62.00%), Query Frame = 3

Query:   63 YDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI-TNYKITNPSHTIVL 653
            +DY+ +LL +G+  VGKT+FL+ Y D  F   F ST+G+DF+ K +              ++ + LQ+WDTAGQER+R++ + ++R AMGF+LM+D+TNEES   V++W   +K  ++ DN  ++L GNK D+   R V+ E+ + +A++    + ETS  + I V++  ++LV+++  ++  S+ T+  +T  + T  L
Sbjct:   18 FDYMFKLLIIGNSSVGKTSFLFRYADDAFTSAFVSTVGIDFKVKTVYKN-----------DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFGAVQDWSTQIKTYSW-DNAQVVLAGNKCDMEEERVVSVESGRLLAEQLGFEFFETSAKDNINVKQTFERLVDLICDKMSESLDTDPAVTTGAPTAKL 205

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BLAST of Ras-related protein Rab-27B vs. Planmine SMEST
Match: SMESG000077907.1 (SMESG000077907.1)

HSP 1 Score: 430.639 bits (1106), Expect = 1.935e-155
Identity = 218/219 (99.54%), Postives = 219/219 (100.00%), Query Frame = 3

Query:   45 MARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLPRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITNPSHTIVLXXXXXXXXXXXFCPFC 701
            MARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLN+REWMNILKANAYCDNPDIILVGNKADLPRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITNPSHTIVLKKDKNKSKSDSFCPFC
Sbjct:    1 MARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNIREWMNILKANAYCDNPDIILVGNKADLPRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITNPSHTIVLKKDKNKSKSDSFCPFC 219

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BLAST of Ras-related protein Rab-27B vs. Planmine SMEST
Match: SMESG000023446.1 (SMESG000023446.1)

HSP 1 Score: 257.684 bits (657), Expect = 7.321e-87
Identity = 121/193 (62.69%), Postives = 149/193 (77.20%), Query Frame = 3

Query:   54 NDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKI 626
            ND+YDYLI+LLALGD +VGKT+ LY YTDG F+P FTST+GVDFRQKRI+  S    D  LG+ Q LHLQLWDTAGQERFRSLC++F RDAMGF+L+FDLTNE SL N REW+ IL A+AYC+ PD++LVGNKADL   R V+ E A++VA+E  + Y+ETS   G  VE  M  L++MVM RIE S++  K+
Sbjct:   14 NDDYDYLIKLLALGDSNVGKTSLLYQYTDGVFNPRFTSTVGVDFRQKRIVRESPRDADGLLGQRQKLHLQLWDTAGQERFRSLCTVFLRDAMGFLLVFDLTNERSLTNCREWLQILSAHAYCEKPDVVLVGNKADLTNQRVVSVEQAERVAKELGVKYMETSAATGNNVENTMSLLLDMVMDRIEKSVSKNKL 206

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BLAST of Ras-related protein Rab-27B vs. Planmine SMEST
Match: SMESG000014812.1 (SMESG000014812.1)

HSP 1 Score: 231.876 bits (590), Expect = 7.201e-77
Identity = 110/187 (58.82%), Postives = 144/187 (77.01%), Query Frame = 3

Query:   57 DEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSI 611
            D+YDYL++LLALGD  VGKT+ L+ YTD +F P F ST+GVDF+QKRI+H S +  +  LG+ Q L LQLWDTAGQERFRSL   FFRDAMGF+L+FD+TNE+S L++R W+ +L+++AYCD PD+ILVGNK DL   R V+ + A+ +A+   +PYIETS L+   VE+A D++V MVM RIE SI
Sbjct:   10 DDYDYLLKLLALGDSAVGKTSLLHRYTDDEFSPKFVSTVGVDFKQKRIVHNS-NTENGVLGKSQKLQLQLWDTAGQERFRSLSMAFFRDAMGFLLVFDVTNEQSFLHIRNWVTVLRSHAYCDTPDMILVGNKIDLEEARQVSFKEAEDLAETLGIPYIETSALSAENVEKAFDQIVVMVMKRIERSI 195

[Close]

BLAST of Ras-related protein Rab-27B vs. Planmine SMEST
Match: SMESG000044557.1 (SMESG000044557.1)

HSP 1 Score: 214.927 bits (546), Expect = 3.382e-70
Identity = 103/186 (55.38%), Postives = 139/186 (74.73%), Query Frame = 3

Query:   48 ARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLP--RTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRI 599
            A ND+YDYLI+LLALGD  VGKT  L  Y D  +   F +T+GVDF+QKR+I+ +   T+  + +E  L+LQLWDTAGQERF+SL   FFRDAMGF+L+FDLT+E S +N+R+WM +LK N+Y +NPDI+LVGNK+DL   R ++ E A ++A+EFN+PY+ETS  +G  VE+A   L+ +VM RI
Sbjct:    7 AGNDDYDYLIKLLALGDSSVGKTCILQRYIDNAYTRDFGNTVGVDFKQKRVIY-TPKNTNGIIEKEARLNLQLWDTAGQERFKSLTVSFFRDAMGFLLVFDLTDENSFINIRDWMRLLKINSYSENPDIVLVGNKSDLSSRRVISHETALELAKEFNVPYLETSASSGENVEKAFQTLIELVMERI 191

[Close]

BLAST of Ras-related protein Rab-27B vs. Planmine SMEST
Match: SMESG000034019.1 (SMESG000034019.1)

HSP 1 Score: 151.754 bits (382), Expect = 1.293e-45
Identity = 72/194 (37.11%), Postives = 123/194 (63.40%), Query Frame = 3

Query:   63 YDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQKRIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLMFDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADL--PRTVTEEAAKKVAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITNPS 638
            +DY+ +LL +G+  VGKT+FL+ Y D  F   F ST+G+DF+ K I+ R           ++ + LQ+WDTAGQER+R++ + ++R AMGF+LM+D+TNEES   V++W+  +K  ++ DN  ++LVGNK DL   R ++ +  +++A +  L + ETS    + V+   ++LV+++  ++  S+     T+PS
Sbjct:   12 FDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTIVRR-----------DKKVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWVTQIKTYSW-DNAQVVLVGNKVDLDYERVISIDRGRQLASQLGLEFFETSAKENLHVKSVFERLVDIICDKMSESLD----TDPS 189

The following BLAST results are available for this feature:

BLAST of Ras-related protein Rab-27B vs. Ensembl Human
BLAST of Ras-related protein Rab-27B vs. Ensembl Celegans
BLAST of Ras-related protein Rab-27B vs. Ensembl Fly
BLAST of Ras-related protein Rab-27B vs. Ensembl Zebrafish
BLAST of Ras-related protein Rab-27B vs. Ensembl Xenopus
BLAST of Ras-related protein Rab-27B vs. Ensembl Mouse
BLAST of Ras-related protein Rab-27B vs. UniProt/SwissProt
BLAST of Ras-related protein Rab-27B vs. TrEMBL
BLAST of Ras-related protein Rab-27B vs. Ensembl Cavefish
BLAST of Ras-related protein Rab-27B vs. Ensembl Sea Lamprey
BLAST of Ras-related protein Rab-27B vs. Ensembl Yeast
BLAST of Ras-related protein Rab-27B vs. Ensembl Nematostella
BLAST of Ras-related protein Rab-27B vs. Ensembl Medaka
BLAST of Ras-related protein Rab-27B vs. Planmine SMEST

BLAST of Ras-related protein Rab-27B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RAB27B	1.840e-78	56.48	RAB27B, member RAS oncogene family [Source:HGNC Sy...	[more]
RAB27A	6.587e-75	54.79	RAB27A, member RAS oncogene family [Source:HGNC Sy...	[more]
RAB27A	6.587e-75	54.79	RAB27A, member RAS oncogene family [Source:HGNC Sy...	[more]
RAB27A	6.587e-75	54.79	RAB27A, member RAS oncogene family [Source:HGNC Sy...	[more]
RAB27A	6.587e-75	54.79	RAB27A, member RAS oncogene family [Source:HGNC Sy...	[more]

BLAST of Ras-related protein Rab-27B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
aex-6	5.487e-68	53.23	Rab27 [Source:UniProtKB/TrEMBL;Acc:G5EBS5]	[more]
rab-3	3.648e-43	37.30	Ras-related protein Rab-3 [Source:UniProtKB/Swiss...	[more]
rab-3	4.784e-43	37.30	Ras-related protein Rab-3 [Source:UniProtKB/Swiss...	[more]
rab-1	2.773e-39	37.23	RAB family [Source:UniProtKB/TrEMBL;Acc:Q9UAQ6]	[more]
4R79.2	1.296e-37	38.50	pep chromosome:WBcel235:IV:17480396:17482329:-1 ge...	[more]

BLAST of Ras-related protein Rab-27B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rab27	1.148e-64	48.97	gene:FBgn0025382 transcript:FBtr0070294	[more]
Rab27	4.696e-60	48.39	gene:FBgn0025382 transcript:FBtr0070293	[more]
Rab3	2.689e-43	35.26	gene:FBgn0005586 transcript:FBtr0473383	[more]
Rab3	2.689e-43	35.26	gene:FBgn0005586 transcript:FBtr0088257	[more]
Rab8	7.717e-38	37.30	gene:FBgn0262518 transcript:FBtr0308833	[more]

BLAST of Ras-related protein Rab-27B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rab27b	5.455e-78	58.06	RAB27B, member RAS oncogene family [Source:ZFIN;Ac...	[more]
rab27b	6.355e-78	58.06	RAB27B, member RAS oncogene family [Source:ZFIN;Ac...	[more]
rab27a	1.094e-74	55.38	RAB27A, member RAS oncogene family [Source:ZFIN;Ac...	[more]
rab3ab	8.922e-45	36.76	RAB3A, member RAS oncogene family, b [Source:ZFIN;...	[more]
rab3c	1.394e-43	36.22	RAB3C, member RAS oncogene family [Source:ZFIN;Acc...	[more]

BLAST of Ras-related protein Rab-27B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lemd3	4.705e-77	55.96	LEM domain containing 3 [Source:Xenbase;Acc:XB-GEN...	[more]
lemd3	8.056e-76	55.38	LEM domain containing 3 [Source:Xenbase;Acc:XB-GEN...	[more]
rab27a	6.505e-71	56.99	RAB27A, member RAS oncogene family [Source:NCBI ge...	[more]
rab27a	1.528e-70	56.99	RAB27A, member RAS oncogene family [Source:NCBI ge...	[more]
rab27a	6.948e-45	45.74	RAB27A, member RAS oncogene family [Source:NCBI ge...	[more]

BLAST of Ras-related protein Rab-27B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rab27b	6.708e-79	55.44	RAB27B, member RAS oncogene family [Source:MGI Sym...	[more]
Rab27b	6.708e-79	55.44	RAB27B, member RAS oncogene family [Source:MGI Sym...	[more]
Rab27b	6.708e-79	55.44	RAB27B, member RAS oncogene family [Source:MGI Sym...	[more]
Rab27a	3.600e-76	55.38	RAB27A, member RAS oncogene family [Source:MGI Sym...	[more]
Rab27a	3.600e-76	55.38	RAB27A, member RAS oncogene family [Source:MGI Sym...	[more]

BLAST of Ras-related protein Rab-27B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q99P58\|RB27B_MOUSE	4.693e-78	55.44	Ras-related protein Rab-27B OS=Mus musculus OX=100...	[more]
sp\|O00194\|RB27B_HUMAN	8.838e-78	56.48	Ras-related protein Rab-27B OS=Homo sapiens OX=960...	[more]
sp\|Q8HZJ5\|RB27B_BOVIN	6.166e-77	56.54	Ras-related protein Rab-27B OS=Bos taurus OX=9913 ...	[more]
sp\|Q99P74\|RB27B_RAT	1.383e-76	53.54	Ras-related protein Rab-27B OS=Rattus norvegicus O...	[more]
sp\|P23640\|RB27A_RAT	2.025e-75	55.38	Ras-related protein Rab-27A OS=Rattus norvegicus O...	[more]

BLAST of Ras-related protein Rab-27B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
Q5BYA6	1.408e-81	61.03	SJCHGC04801 protein (Fragment) OS=Schistosoma japo...	[more]
C1L3U1	2.096e-81	61.03	Rab-protein 8 OS=Schistosoma japonicum OX=6182 GN=...	[more]
A0A095AT55	1.417e-80	61.03	Ras-related protein Rab-27B OS=Schistosoma haemato...	[more]
A0A183NVF6	1.496e-80	61.03	Uncharacterized protein OS=Schistosoma mattheei OX...	[more]
A0A3Q0KN12	1.546e-80	61.03	Putative rab OS=Schistosoma mansoni OX=6183 PE=4 S...	[more]

BLAST of Ras-related protein Rab-27B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rab27b	6.845e-79	58.60	RAB27B, member RAS oncogene family [Source:NCBI ge...	[more]
rab27a	6.839e-76	55.91	RAB27A, member RAS oncogene family [Source:NCBI ge...	[more]
rab27a	6.839e-76	55.91	RAB27A, member RAS oncogene family [Source:NCBI ge...	[more]
rab3ab	3.538e-44	36.22	RAB3A, member RAS oncogene family [Source:NCBI gen...	[more]
rab3ab	3.538e-44	36.22	RAB3A, member RAS oncogene family [Source:NCBI gen...	[more]

BLAST of Ras-related protein Rab-27B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rab27a	1.227e-65	49.73	RAB27A, member RAS oncogene family [Source:ZFIN;Ac...	[more]
rab27a	9.414e-51	64.04	RAB27A, member RAS oncogene family [Source:ZFIN;Ac...	[more]
rab3c	7.713e-45	36.32	RAB3C, member RAS oncogene family [Source:ZFIN;Acc...	[more]
rab27a	8.087e-43	52.42	RAB27A, member RAS oncogene family [Source:ZFIN;Ac...	[more]
rab8a	5.289e-40	36.95	RAB8A, member RAS oncogene family [Source:ZFIN;Acc...	[more]

BLAST of Ras-related protein Rab-27B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
SEC4	2.766e-39	36.07	Rab family GTPase; essential for vesicle-mediated ...	[more]
YPT31	1.508e-33	35.16	Rab family GTPase; involved in the exocytic pathwa...	[more]
YPT1	2.607e-33	36.99	Rab family GTPase; involved in the ER-to-Golgi ste...	[more]
YPT32	1.775e-31	36.00	Rab family GTPase involved in the exocytic pathway...	[more]
YPT7	1.603e-28	31.32	Rab family GTPase; GTP-binding protein of the rab ...	[more]

BLAST of Ras-related protein Rab-27B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO49958	4.840e-71	51.81	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28309	2.159e-67	53.37	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34944	1.100e-43	36.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41018	1.305e-38	35.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40167	1.492e-38	37.97	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Ras-related protein Rab-27B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rab27b	3.900e-78	57.53	RAB27B, member RAS oncogene family [Source:NCBI ge...	[more]
rab27a	3.749e-72	54.30	RAB27A, member RAS oncogene family [Source:NCBI ge...	[more]
ENSORLT00000000515.2	4.755e-70	54.04	ras-related protein Rab-27B [Source:NCBI gene;Acc:...	[more]
rab27a	7.001e-61	56.13	RAB27A, member RAS oncogene family [Source:NCBI ge...	[more]
rab3c	7.593e-44	35.50	RAB3C, member RAS oncogene family [Source:NCBI gen...	[more]

BLAST of Ras-related protein Rab-27B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000077907.1	1.935e-155	99.54	SMESG000077907.1	[more]
SMESG000023446.1	7.321e-87	62.69	SMESG000023446.1	[more]
SMESG000014812.1	7.201e-77	58.82	SMESG000014812.1	[more]
SMESG000044557.1	3.382e-70	55.38	SMESG000044557.1	[more]
SMESG000034019.1	1.293e-45	37.11	SMESG000034019.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30003458 ID=SMED30003458|Name=Ras-related protein Rab-27B|organism=Schmidtea mediterranea sexual|type=transcript|length=722bp
CGATCTCGCGTCATTGATTTCAAGAATTTAATTATTTTTGAGTCATGGCT
CGCAATGATGAATATGATTATCTCATTAGGCTGCTTGCATTAGGAGATCA
GGACGTTGGGAAAACCACATTTTTGTACTATTACACTGATGGAAAATTTG
ATCCAGGATTCACGTCTACTATTGGAGTTGACTTTCGTCAGAAAAGAATT
ATTCATCGATCAGTCGATAAAACTGACAGCTGCCTCGGCGAGGAACAAAT
TCTTCACTTACAATTATGGGATACCGCCGGCCAGGAAAGATTTCGGAGCC
TTTGCTCTATATTCTTTCGTGATGCAATGGGCTTTGTTTTAATGTTTGAT
CTAACAAATGAGGAAAGCCTACTGAATGTTAGAGAATGGATGAATATTCT
GAAGGCAAATGCCTATTGCGATAATCCAGATATTATATTAGTGGGGAATA
AAGCCGATTTACCCAGAACAGTAACTGAAGAAGCGGCCAAAAAAGTTGCA
CAAGAATTTAATTTACCATATATTGAAACGAGCGGTCTGAATGGAATACG
AGTTGAAGAGGCCATGGATAAACTTGTGAATATGGTAATGACAAGAATCG
AAAACTCAATCACTAATTATAAAATAACAAATCCATCGCATACAATTGTT
CTCAAAAAAGATAAAAATAAATCAAAAAGTGACAGCTTCTGTCCATTTTG
TTAAATATTTTTAAAAATCTAG

protein sequence of SMED30003458-orf-1

>SMED30003458-orf-1 ID=SMED30003458-orf-1|Name=SMED30003458-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=220bp
MARNDEYDYLIRLLALGDQDVGKTTFLYYYTDGKFDPGFTSTIGVDFRQK
RIIHRSVDKTDSCLGEEQILHLQLWDTAGQERFRSLCSIFFRDAMGFVLM
FDLTNEESLLNVREWMNILKANAYCDNPDIILVGNKADLPRTVTEEAAKK
VAQEFNLPYIETSGLNGIRVEEAMDKLVNMVMTRIENSITNYKITNPSHT
IVLKKDKNKSKSDSFCPFC*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003924	GTPase activity
GO:0005525	GTP binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000034	epidermis

Vocabulary: **INTERPRO**
Term	Definition
IPR005225	Small_GTP-bd_dom
IPR027417	P-loop_NTPase
IPR001806	Small_GTPase

Vocabulary: **biological process**
Term	Definition
GO:0007264	small GTPase mediated signal transduction

Vocabulary: **cellular component**
Term	Definition
GO:0005622	intracellular

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PRINTS	PR00449	RASTRNSFRMNG	coord: 34..50 score: 33.24 coord: 11..32 score: 34.28 coord: 159..181 score: 28.91 coord: 126..139 score: 54.02 coord: 63..85 score: 43.56
None	No IPR available	SMART	SM00174	rho_sub_3	coord: 13..184 e-value: 2.4E-10 score: 13.4
None	No IPR available	SMART	SM00175	rab_sub_5	coord: 11..184 e-value: 4.5E-57 score: 205.6
None	No IPR available	SMART	SM00173	ras_sub_4	coord: 12..184 e-value: 5.4E-11 score: 39.1
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 6..198 e-value: 1.8E-57 score: 195.8
None	No IPR available	PANTHER	PTHR24073	FAMILY NOT NAMED	coord: 8..196
None	No IPR available	PANTHER	PTHR24073:SF587	RAS-RELATED PROTEIN RAB-27B	coord: 8..196
None	No IPR available	PROSITE	PS51419	RAB	coord: 6..216 score: 28.439
IPR001806	Small GTPase	PFAM	PF00071	Ras	coord: 13..182 e-value: 5.8E-44 score: 149.6
IPR005225	Small GTP-binding protein domain	TIGRFAM	TIGR00231	TIGR00231	coord: 10..177 e-value: 1.7E-22 score: 77.9
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 6..185