SMED30003432
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30003432 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Alignments
SMED30003432 aligns in the following genomic locations:
Homology
BLAST of SMED30003432 vs. Ensembl Human
Match: ABCB1 (ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40]) HSP 1 Score: 449.899 bits (1156), Expect = 8.751e-144 Identity = 229/565 (40.53%), Postives = 354/565 (62.65%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDLT------------------MTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 VS + +FR++ +D L ++V +++I GA PL +L+F ++ ++ + +L M E M ++ + + ++ +IQ+ L A RQ ++R +F+A++RQEI WFD G+L T+LTDDV I GI DK+ F Q +++F I+ FT GWKL+ + P++ + ++ + ++ K++ AY+ AG +AEE+L++IRTV+AF Q+KE++RY+ NL+EA+ +G+K++I + G I+ +L ++ G + G Y G V+ +F +++IG+ ++G A P +E F A+ AAY +F++ID P I S+ K G P++ G++EF+NV F YP+R V IL+ N + G+TVA +G SG GKST + L+QR YDP G +S G D++ I++ + R IGVV QEP LF+ +I ENI+ G+ + +EI K+ +++NAY+FIMK KF+T +G+RGA SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK A RT +++AHRL TVRNAD Sbjct: 34 VSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNRSDINDTGFFMNLEEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSGEYSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK--ARKGRTTIVIAHRLSTVRNAD 596 HSP 2 Score: 332.028 bits (850), Expect = 6.902e-100 Identity = 181/497 (36.42%), Postives = 286/497 (57.55%), Query Frame = -1 Query: 1 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGT------------VIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1440 F L +FI+ F+Q T ++RLR F ++LRQ++ WFD K TG L T+L +D ++ I +LA Q I++ II++F GW+L+ + +PI+A + + + ++K K +G IA E + + RTVV+ + ++K Y+ +L+ ++++ + G T +++Y F Y G + G V+ +F +V G++A+G ++ AK +A + +I++ P I S+ G++P + G++ F V F YPTRP +P+LQ + + G+T+A +G SG GKST++ LL+RFYDPLAG++ G ++K +++ W R+H+G+V QEP LF SI ENI G + EEIV++ +++N + FI K++T +GD+G SGGQKQRIAIA ALVR P +LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 759 FLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKA-------HIFGITFSFTQAMMY-----FSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISAAHIIMIIEKTPLIDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK--AREGRTCIVIAHRLSTIQNAD 1241
BLAST of SMED30003432 vs. Ensembl Human
Match: ABCB1 (ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40]) HSP 1 Score: 449.899 bits (1156), Expect = 8.751e-144 Identity = 229/565 (40.53%), Postives = 354/565 (62.65%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDLT------------------MTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 VS + +FR++ +D L ++V +++I GA PL +L+F ++ ++ + +L M E M ++ + + ++ +IQ+ L A RQ ++R +F+A++RQEI WFD G+L T+LTDDV I GI DK+ F Q +++F I+ FT GWKL+ + P++ + ++ + ++ K++ AY+ AG +AEE+L++IRTV+AF Q+KE++RY+ NL+EA+ +G+K++I + G I+ +L ++ G + G Y G V+ +F +++IG+ ++G A P +E F A+ AAY +F++ID P I S+ K G P++ G++EF+NV F YP+R V IL+ N + G+TVA +G SG GKST + L+QR YDP G +S G D++ I++ + R IGVV QEP LF+ +I ENI+ G+ + +EI K+ +++NAY+FIMK KF+T +G+RGA SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK A RT +++AHRL TVRNAD Sbjct: 34 VSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNRSDINDTGFFMNLEEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSGEYSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK--ARKGRTTIVIAHRLSTVRNAD 596 HSP 2 Score: 332.028 bits (850), Expect = 6.902e-100 Identity = 181/497 (36.42%), Postives = 286/497 (57.55%), Query Frame = -1 Query: 1 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGT------------VIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1440 F L +FI+ F+Q T ++RLR F ++LRQ++ WFD K TG L T+L +D ++ I +LA Q I++ II++F GW+L+ + +PI+A + + + ++K K +G IA E + + RTVV+ + ++K Y+ +L+ ++++ + G T +++Y F Y G + G V+ +F +V G++A+G ++ AK +A + +I++ P I S+ G++P + G++ F V F YPTRP +P+LQ + + G+T+A +G SG GKST++ LL+RFYDPLAG++ G ++K +++ W R+H+G+V QEP LF SI ENI G + EEIV++ +++N + FI K++T +GD+G SGGQKQRIAIA ALVR P +LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 759 FLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKA-------HIFGITFSFTQAMMY-----FSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISAAHIIMIIEKTPLIDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK--AREGRTCIVIAHRLSTIQNAD 1241
BLAST of SMED30003432 vs. Ensembl Human
Match: ABCB5 (ATP binding cassette subfamily B member 5 [Source:HGNC Symbol;Acc:HGNC:46]) HSP 1 Score: 439.113 bits (1128), Expect = 7.333e-140 Identity = 234/562 (41.64%), Postives = 354/562 (62.99%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSP----------RDLTMT---FSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGS--YDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISH-KKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V ++FRFA G+D+ ++I+ I++S+ GA PL L+ ++ + L+S ++ T + +E M + + + I G+IQ+ +TAARQ++R+R +F+++L Q+I WFD G+L T++TDD++ I GI DK+A Q +S+F + + GWKL+ + + P++ + + + + K++ AYS AG +AEE+LSSIRTV+AF AQEKE++RY+ NLK+A+ G+KR+I + G + F + L ++ G I G Y GTV+ +F +++ S +G AVP E F A+ AA+ +FQVID+ P I + G PES G +EFKNV F YP+RP + IL+ N + G+TVA +G +GSGKST++ LLQR YDP G I D++ +++ YR HIGVV QEP LF +I NI+ G+ D +EE+ ++ +++NAY+FIM+ KFNT +G++GA SGGQKQRIAIA ALVRNP++L+LDEATSALD+ S+ VQ L+K A RT ++VAHRL T+R+AD Sbjct: 31 VGSIEIFRFADGLDITLMILGILASLVNGACLPLMPLVLGEMSDNLISGCLVQTNTTNYQNCTQSQEKLNEDMTLLTLYYVGIGVAALIFGYIQISLWIITAARQTKRIRKQFFHSVLAQDIGWFDSCDIGELNTRMTDDIDKISDGIGDKIALLFQNMSTFSIGLAVGLVKGWKLTLVTLSTSPLIMASAAACSRMVISLTSKELSAYSKAGAVAEEVLSSIRTVIAFRAQEKELQRYTQNLKDAKDFGIKRTIASKVSLGAVYFFMNGTYGLAFWYGTSLILNGEPGYTIGTVLAVFFSVIHSSYCIGAAVPHFETFAIARGAAFHIFQVIDKKPSIDNFSTAGYKPESIEGTVEFKNVSFNYPSRPSIKILKGLNLRIKSGETVALVGLNGSGKSTVVQLLQRLYDPDDGFIMVDENDIRALNVRHYRDHIGVVSQEPVLFGTTISNNIKYGRDDVTDEEMERAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEK--ASKGRTTIVVAHRLSTIRSAD 590 HSP 2 Score: 310.457 bits (794), Expect = 3.081e-92 Identity = 185/531 (34.84%), Postives = 289/531 (54.43%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQ--TGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNL--------KEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAIN--EEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G P+ +IF ++ + + T+ + + F IL F+S F+Q + + RLR F A+L Q+I WFD+++ TG L T L D+ I+ ++ Q ++ +I++F GW+++F+ P++A T + + ++ K + AG IA E L +IRT+V+ + ++ + Y L K+A+ +G C I F + G + G I G P + +F I G++A+G + + + AK+ A LF ++++ P I S + G P++ G++EF+ V F YP RP V IL+ + ++ GKTVAF+G SG GKST + LLQR YDP+ G++ F G D K++++ W RS I +V QEP LF+ SI ENI G + +EI ++ +N + FI +K+NT +G +GA SGGQKQR+AIA AL++ P++LLLDEATSALDN SEK+VQ LDK A RT ++V HRL ++NAD Sbjct: 703 GTVHPVFSIIFAKIITMFGNNDKTTLKHDAEIYSMI--FVILGVICFVSYFMQGLFYGRAGEILTMRLRHLAFKAMLYQDIAWFDEKENSTGGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIISFIYGWEMTFLILSIAPVLAVTGMIETAAMTGFANKDKQELKHAGKIATEALENIRTIVSLTREKAFEQMYEEMLQTQHRNTSKKAQIIGS----CYAFSHAFIYFA-YAAG---FRFGAYLIQAGRMTPEGMFIVFTAIAYGAMAIGETLVLAPEYSKAKSGAAHLFALLEKKPNIDSRSQEGKKPDTCEGNLEFREVSFFYPCRPDVFILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQEPVLFNCSIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK--ARTGRTCLVVTHRLSAIQNAD 1221
BLAST of SMED30003432 vs. Ensembl Human
Match: ABCB4 (ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]) HSP 1 Score: 419.083 bits (1076), Expect = 1.769e-132 Identity = 226/556 (40.65%), Postives = 341/556 (61.33%), Query Frame = -1 Query: 1 LFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVS-------PRDLTMTF-------SERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1623 LFR++ D L + + I +I G+ PL +++F ++ + V P + +++ E M ++ L + ++ +IQ+ +L A RQ R++R +F+A+LRQEI WFD T +L T+LTDD+ I GI DK+ F Q +++F I+ F GWKL+ + PI+ + ++ + +S K++ AY+ AG +AEE L +IRTV+AF Q KE++RY +L+ A+ +G+K++I + G+ I+ +L ++ G + Y G + +F +I+IG+ ++G A P ++ F A+ AAY +F +ID P+I S + G P+S G++EF +V F YP+R V IL+ N + G+TVA +G SG GKST + L+QR YDP G I+ G D+++ ++ + R IGVV QEP LFS +I ENI G+ + +EI K+ +++NAYEFIMK QKF+T +G+RGA SGGQKQRIAIA ALVRNP++LLLDEATSALD SE VQ LDK A RT +++AHRL TVRNAD Sbjct: 45 LFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVDTAGNFSFPVNFSLSLLNPGKILEEEMTRYAYYYSGLGAGVLVAAYIQVSFWTLAAGRQIRKIRQKFFHAILRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILSAFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKEIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSERGHKPDSIKGNLEFNDVHFSYPSRANVKILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEFIMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDK--AREGRTTIVIAHRLSTVRNAD 598 HSP 2 Score: 317.39 bits (812), Expect = 7.861e-95 Identity = 182/485 (37.53%), Postives = 263/485 (54.23%), Query Frame = -1 Query: 1 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1440 F L +F + F+Q T +RRLRS F A+LRQ++ WFD K TG L T+L D ++ +LA Q I++ II++F GW+L+ + +PI+A + + + + + + K AG IA E + +IRTVV+ + + K Y L Y P ++F IV G++ALG+A ++ AK +A LF + +R P I S+ + G+ P+ F G+I F V F YPTR VP+LQ + + G+T+A +G SG GKST++ LL+RFYDPLAG + G + K +++ W R+ +G+V QEP LF SI ENI G + +EIV + + +N + FI K+ T +GD+G SGGQKQRIAIA AL+R PQ+LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 758 FLFLGIISFFTFFLQGFTFGKAGEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNIANLGTGIIISFIYGWQLTLLLLAVVPIIAVSGIVEMKLLAGNAKRDKKELEAAGKIATEAIENIRTVVSLTQERKFESMYVEKL--------------------------------------------YGP---YRVFSAIVFGAVALGHASSFAPDYAKAKLSAAHLFMLFERQPLIDSYSEEGLKPDKFEGNITFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIETLPHKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDK--AREGRTCIVIAHRLSTIQNAD 1193
BLAST of SMED30003432 vs. Ensembl Human
Match: ABCB4 (ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]) HSP 1 Score: 419.083 bits (1076), Expect = 1.769e-132 Identity = 226/556 (40.65%), Postives = 341/556 (61.33%), Query Frame = -1 Query: 1 LFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVS-------PRDLTMTF-------SERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1623 LFR++ D L + + I +I G+ PL +++F ++ + V P + +++ E M ++ L + ++ +IQ+ +L A RQ R++R +F+A+LRQEI WFD T +L T+LTDD+ I GI DK+ F Q +++F I+ F GWKL+ + PI+ + ++ + +S K++ AY+ AG +AEE L +IRTV+AF Q KE++RY +L+ A+ +G+K++I + G+ I+ +L ++ G + Y G + +F +I+IG+ ++G A P ++ F A+ AAY +F +ID P+I S + G P+S G++EF +V F YP+R V IL+ N + G+TVA +G SG GKST + L+QR YDP G I+ G D+++ ++ + R IGVV QEP LFS +I ENI G+ + +EI K+ +++NAYEFIMK QKF+T +G+RGA SGGQKQRIAIA ALVRNP++LLLDEATSALD SE VQ LDK A RT +++AHRL TVRNAD Sbjct: 45 LFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVDTAGNFSFPVNFSLSLLNPGKILEEEMTRYAYYYSGLGAGVLVAAYIQVSFWTLAAGRQIRKIRQKFFHAILRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILSAFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKEIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSERGHKPDSIKGNLEFNDVHFSYPSRANVKILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEFIMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDK--AREGRTTIVIAHRLSTVRNAD 598 HSP 2 Score: 317.39 bits (812), Expect = 7.861e-95 Identity = 182/485 (37.53%), Postives = 263/485 (54.23%), Query Frame = -1 Query: 1 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1440 F L +F + F+Q T +RRLRS F A+LRQ++ WFD K TG L T+L D ++ +LA Q I++ II++F GW+L+ + +PI+A + + + + + + K AG IA E + +IRTVV+ + + K Y L Y P ++F IV G++ALG+A ++ AK +A LF + +R P I S+ + G+ P+ F G+I F V F YPTR VP+LQ + + G+T+A +G SG GKST++ LL+RFYDPLAG + G + K +++ W R+ +G+V QEP LF SI ENI G + +EIV + + +N + FI K+ T +GD+G SGGQKQRIAIA AL+R PQ+LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 758 FLFLGIISFFTFFLQGFTFGKAGEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNIANLGTGIIISFIYGWQLTLLLLAVVPIIAVSGIVEMKLLAGNAKRDKKELEAAGKIATEAIENIRTVVSLTQERKFESMYVEKL--------------------------------------------YGP---YRVFSAIVFGAVALGHASSFAPDYAKAKLSAAHLFMLFERQPLIDSYSEEGLKPDKFEGNITFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIETLPHKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDK--AREGRTCIVIAHRLSTIQNAD 1193
BLAST of SMED30003432 vs. Ensembl Celegans
Match: pgp-9 (p-GlycoProtein related [Source:UniProtKB/TrEMBL;Acc:G5EG58]) HSP 1 Score: 402.519 bits (1033), Expect = 2.844e-126 Identity = 222/561 (39.57%), Postives = 326/561 (58.11%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVN-------LLVSPRDLT-------MTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 +S +QL+R+ + +D L++ V II S G PL +I +V + + P FS + + +K+ L F +GF+Q + + S R R +F++++RQEI W+DK +G L KL D++E + G DK+ Q ++ F+G +AFT W L+ I P M + + + K+ K Y++AGGIAEE+L+SIRTV+AF+ QE E KRY L+ + G+K+S G G I+ L +++G F+Y G + GTV+ +F ++++GS+ALG A TA AA L++VIDR+P+I ++ G P G I V+F YPTR V IL+ + G+TVA +G SG GKSTII LLQRFY+P AG+I ++D ++ + R +GVV QEP LF+ SI++NI+ G+ D +E+I ++ +++NA +FI + NT +GDRG SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ L+ A RT +++AHRL TVRNAD Sbjct: 29 ISIFQLYRYTSTVDRLMLAVGIIVSCATGVGLPLMSIIMGNVSQNFVTLGTIFLDPNSTASEKAAARAEFSHEVIQNCLKYVYLGCGIFAAGFLQASCFMVICEKLSNRFRRQFFHSVMRQEIAWYDKNTSGTLSNKLFDNLERVREGTGDKVGLAFQMMAQFIGGFAVAFTYDWLLTLIMMSLSPFMMICGLFLAKLLATAATKEAKQYAVAGGIAEEVLTSIRTVIAFNGQEYECKRYEDALEHGKKTGIKKSFLIGAGLASFFVIIYASYCLAFWVGTNFVYSGRLESGTVLTVFFSVMMGSMALGQAGQQFATIGTALGAAASLYEVIDRIPEIDAYSTEGQTPSKISGRISVNKVEFTYPTRADVKILKGVSLDAQPGQTVALVGSSGCGKSTIIQLLQRFYNPDAGQILIDDIPIEDFNIKYLRQLVGVVSQEPNLFNTSIEQNIRYGRSDVSDEDIARALKEANAADFIKTFPEGLNTLVGDRGVQMSGGQKQRIAIARALVRNPKILLLDEATSALDAESESIVQSALEN--ASRGRTTIVIAHRLSTVRNAD 587 HSP 2 Score: 298.516 bits (763), Expect = 3.303e-88 Identity = 182/524 (34.73%), Postives = 275/524 (52.48%), Query Frame = -1 Query: 4 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGS--YDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKM--DAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNA 1554 GA P L F ++N+ +P M + F +L++ S Q + A R + R+RS + +LRQ+ +FD K G++ T+L D +I+S I +L + I+S G + +AF GW+++F+ P MA +LM+ + + K AG A E + +IRTV A + Q K + +L + ++I +GL G F + + GL I++ + +P V+++ I +G A +I A AA +F +++ P+I G P+ G+++ V F YP RP VPILQ N + G+T+A +GPSG GKST+I LL+R YDPL G ++ DL+ ++ R HI +V QEP LF SI+ENI G + +E+I + +N ++FI + + T +G++G SGGQKQRIAIA AL+RNP++LLLDEATSALD SEK VQ LD A RT ++VAHRL T+ NA Sbjct: 717 GAVMPAFSLFFSQIINVFSNPDRDQMKKDGHFW--ALMFLVLAAVQGTSMLFQCSLFGVAAERLTMRIRSKVYRNVLRQDATYFDMPKHSPGRITTRLATDAPNIKSAIDYRLGSIFNAIASVGGGLGIAFYYGWQMAFLVMAIFPFMAVGQALMMKYHGGSATSDAKEMENAGKTAMEAIENIRTVQALTLQTKLYNIFCSHLDAPHGGNISKAIIRGLTYGFANSIQFFTYAAAFRFGLFLIFDKNVLMEPENVLRVLFAISFSFGTIGFAASYFPEYIKATFAAGLIFNMLEEEPRIDGMTSSGTYPQ-LSGEVKLNKVFFRYPERPAVPILQGLNVHVKPGQTLALVGPSGCGKSTVISLLERLYDPLEGAVTVDNNDLRQMNPKHLRKHIALVSQEPILFDTSIRENIVYGLQPGEYTHEQIETACSKANIHKFIDELPDGYETRVGEKGTQLSGGQKQRIAIARALIRNPKILLLDEATSALDTESEKQVQVALDA--AAKDRTCIVVAHRLSTIVNA 1235
BLAST of SMED30003432 vs. Ensembl Celegans
Match: pgp-1 (Multidrug resistance protein pgp-1 [Source:UniProtKB/Swiss-Prot;Acc:P34712]) HSP 1 Score: 389.808 bits (1000), Expect = 2.424e-121 Identity = 221/563 (39.25%), Postives = 336/563 (59.68%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPL---------------NVLIFRDVVNLLVSPRDLTMT-FSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 VS QL+R+ T ++ L++ + + ++ GA PL ++I + L + ++ T T F + V +A ++ + +G I + A + + RLR + ++LRQEI WFD +G L TKL D++E ++ G DK+ Q +S F+ I+AFT W+L+ + PI A + + ++I++ Y+ AG + EE +SSIRTVV+ + E++RYS ++EA+ GV + + G+ G + + F +L +Y+G+ ++++GS + G ++ F ++++GS+ALG A P L TA+ AA +++V+DR P I S K G GDI +NV F YP+RP VPIL+ N + G+TVA +G SG GKSTII LL R+YD L G+I+ G D++DI+L + R ++ VV QEP LF+ +I+ENI LGK EE+V + + +NA +FI +NT +GDRG SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ+ LDK A RT +++AHRL T+RNAD Sbjct: 60 VSIPQLYRYTTTLEKLLLFIGTLVAVITGAGLPLMSILQGKVSQAFINEQIVINNNGSTFLPTGQNYTKTDFEHDVMNVVWSYAAMTVGMWAAGQITVTCYLYVAEQMNNRLRREFVKSILRQEISWFDTNHSGTLATKLFDNLERVKEGTGDKIGMAFQYLSQFITGFIVAFTHSWQLTLVMLAVTPIQALCGFAIAKSMSTFAIRETLRYAKAGKVVEETISSIRTVVSLNGLRYELERYSTAVEEAKKAGVLKGLFLGISFGAMQASNFISFALAFYIGVGWVHDGSLNFGDMLTTFSSVMMGSMALGLAGPQLAVLGTAQGAASGIYEVLDRKPVIDSSSKAGRKDMKIKGDITVENVHFTYPSRPDVPILRGMNLRVNAGQTVALVGSSGCGKSTIISLLLRYYDVLKGKITIDGVDVRDINLEFLRKNVAVVSQEPALFNCTIEENISLGKEGITREEMVAACKMANAEKFIKTLPNGYNTLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESEGIVQQALDK--AAKGRTTIIIAHRLSTIRNAD 620 HSP 2 Score: 293.508 bits (750), Expect = 2.010e-86 Identity = 172/488 (35.25%), Postives = 268/488 (54.92%), Query Frame = -1 Query: 1 IKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQ--TGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEG--SYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1446 + F +L++ I F+ + + + +R LR+ F +L Q I +FD Q +G++ T+L DV ++ + I + + I + S V I LAF GW+++ + +PI+A L ++K ++ +G IA E + ++RTV A + ++ + + L +K + QGL G ++ + + Y MGL I + P V+++ I I + LG A + A A +F ++ ++ +I + YG + FKNV F YP RP + IL+ +F++ G+T+A +GPSG GKST++ LL+RFYD L GEI G+++K ++ RS I +V QEP LF SI ENI G ++ ++ + +N + FI + + F T +GDRG SGGQKQRIAIA ALVRNP++LLLDEATSALD SEK+VQ+ LD+ A RT +++AHRL TV NAD Sbjct: 798 LMFLVLAAAQGICSFLMTFFMGIASESLTRDLRNKLFRNVLSQHIGFFDSPQNASGKISTRLATDVPNLRTAIDFRFSTVITTLVSMVAGIGLAFFYGWQMALLIIAILPIVAFGQYLRGRRFTGKNVKSASEFADSGKIAIEAIENVRTVQALAREDTFYENFCEKLDIPHKEAIKEAFIQGLSYGCASSVLYLLNTCAYRMGLALIITDPPTMQPMRVLRVMYAITISTSTLGFATSYFPEYAKATFAGGIIFGMLRKISKIDSLSLAGEKKKLYGKVIFKNVRFAYPERPEIEILKGLSFSVEPGQTLALVGPSGCGKSTVVALLERFYDTLGGEIFIDGSEIKTLNPEHTRSQIAIVSQEPTLFDCSIAENIIYGLDPSSVTMAQVEEAARLANIHNFIAELPEGFETRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEKVVQEALDR--AREGRTCIVIAHRLNTVMNAD 1283
BLAST of SMED30003432 vs. Ensembl Celegans
Match: pgp-2 (ABC transporter PGP-2; p-GlycoProtein related [Source:UniProtKB/TrEMBL;Acc:G5EDF9]) HSP 1 Score: 377.096 bits (967), Expect = 4.938e-117 Identity = 202/563 (35.88%), Postives = 329/563 (58.44%), Query Frame = -1 Query: 1 YQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLL--------------VSPRDLTMTFSERMRPSVIKFAI----LSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMG-LLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1629 Y +F + G+DLL++I ++++ GA FPL ++ + + V+P L + V+K+ I L F + ++Q+ A R +LR NY A+LRQ+I WFDKQQTG L +LTDD+E + G+ DK A +Q ++F+ + F W ++ + P++ + + M + + + + Y++AG IAEE SSIRTV + + ++E+ R+ + L+ G+ + G+G G +++ +L ++ G L I + ++D G + +F ++ GS +LG A+P L +F TA+ AA + +VI+ P+I + G++ ++ GDI FK+V F YP+R + +L+ + L G +A +G SG GKSTI++LLQRFYDP G + G DL+++++ R IG+V QEP LF G+I ENI++G A ++++V++ + +NA +FI + + T +G++G SGGQKQRIAIA ALV+NP++LLLDEATSALD +E+ VQ LD+ A+ RT ++VAHRL T+RN D Sbjct: 36 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ--AQAGRTTIIVAHRLSTIRNVD 596 HSP 2 Score: 276.944 bits (707), Expect = 1.113e-80 Identity = 177/535 (33.08%), Postives = 286/535 (53.46%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFA---ILSSCTFISGFIQMVT-ISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIP--IMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEK------EVKR--YSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG-KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G+ P+ L++ ++ N+ P D +M+ +V + +L TF GF + + +LR F LLRQ+I ++D + TG+L T+ D ++ + +L + I + G + + F GW+L+ I + +P +M F + + F K+ I+ + AG +A + + IRTV + + QE+ E R ++ NLK A T G + Q L IF + + +Y+G +F+ + + P V ++F I +GN + + + A+ AA LF +I+ I I + G+I +NV F YPTR +LQ F + GKTVA +G SG GKSTI+ LL+RFY+ G I G ++++++++ R + +V QEP LF +I ENI G + +EIV++ + +N + FI+ ++T +G++G SGGQKQRIAIA ALVR+P +LLLDEATSALD SEK+VQ+ LD A+ RT +++AHRL T++N+D Sbjct: 712 GSVTPVFALVYAEIFNVYSLPAD-------QMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQLALILVVMVPLLVMGGYFEMQMRFGKQ--IRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSL--------IFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDA--AKQGRTCLVIAHRLSTIQNSD 1226
BLAST of SMED30003432 vs. Ensembl Celegans
Match: pgp-2 (ABC transporter PGP-2; p-GlycoProtein related [Source:UniProtKB/TrEMBL;Acc:G5EDF9]) HSP 1 Score: 377.096 bits (967), Expect = 5.628e-117 Identity = 202/563 (35.88%), Postives = 329/563 (58.44%), Query Frame = -1 Query: 1 YQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLL--------------VSPRDLTMTFSERMRPSVIKFAI----LSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMG-LLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1629 Y +F + G+DLL++I ++++ GA FPL ++ + + V+P L + V+K+ I L F + ++Q+ A R +LR NY A+LRQ+I WFDKQQTG L +LTDD+E + G+ DK A +Q ++F+ + F W ++ + P++ + + M + + + + Y++AG IAEE SSIRTV + + ++E+ R+ + L+ G+ + G+G G +++ +L ++ G L I + ++D G + +F ++ GS +LG A+P L +F TA+ AA + +VI+ P+I + G++ ++ GDI FK+V F YP+R + +L+ + L G +A +G SG GKSTI++LLQRFYDP G + G DL+++++ R IG+V QEP LF G+I ENI++G A ++++V++ + +NA +FI + + T +G++G SGGQKQRIAIA ALV+NP++LLLDEATSALD +E+ VQ LD+ A+ RT ++VAHRL T+RN D Sbjct: 43 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ--AQAGRTTIIVAHRLSTIRNVD 603 HSP 2 Score: 276.944 bits (707), Expect = 1.155e-80 Identity = 177/535 (33.08%), Postives = 286/535 (53.46%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFA---ILSSCTFISGFIQMVT-ISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIP--IMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEK------EVKR--YSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG-KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G+ P+ L++ ++ N+ P D +M+ +V + +L TF GF + + +LR F LLRQ+I ++D + TG+L T+ D ++ + +L + I + G + + F GW+L+ I + +P +M F + + F K+ I+ + AG +A + + IRTV + + QE+ E R ++ NLK A T G + Q L IF + + +Y+G +F+ + + P V ++F I +GN + + + A+ AA LF +I+ I I + G+I +NV F YPTR +LQ F + GKTVA +G SG GKSTI+ LL+RFY+ G I G ++++++++ R + +V QEP LF +I ENI G + +EIV++ + +N + FI+ ++T +G++G SGGQKQRIAIA ALVR+P +LLLDEATSALD SEK+VQ+ LD A+ RT +++AHRL T++N+D Sbjct: 719 GSVTPVFALVYAEIFNVYSLPAD-------QMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQLALILVVMVPLLVMGGYFEMQMRFGKQ--IRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSL--------IFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDA--AKQGRTCLVIAHRLSTIQNSD 1233
BLAST of SMED30003432 vs. Ensembl Celegans
Match: pgp-2 (ABC transporter PGP-2; p-GlycoProtein related [Source:UniProtKB/TrEMBL;Acc:G5EDF9]) HSP 1 Score: 377.481 bits (968), Expect = 6.183e-117 Identity = 202/563 (35.88%), Postives = 329/563 (58.44%), Query Frame = -1 Query: 1 YQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLL--------------VSPRDLTMTFSERMRPSVIKFAI----LSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMG-LLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1629 Y +F + G+DLL++I ++++ GA FPL ++ + + V+P L + V+K+ I L F + ++Q+ A R +LR NY A+LRQ+I WFDKQQTG L +LTDD+E + G+ DK A +Q ++F+ + F W ++ + P++ + + M + + + + Y++AG IAEE SSIRTV + + ++E+ R+ + L+ G+ + G+G G +++ +L ++ G L I + ++D G + +F ++ GS +LG A+P L +F TA+ AA + +VI+ P+I + G++ ++ GDI FK+V F YP+R + +L+ + L G +A +G SG GKSTI++LLQRFYDP G + G DL+++++ R IG+V QEP LF G+I ENI++G A ++++V++ + +NA +FI + + T +G++G SGGQKQRIAIA ALV+NP++LLLDEATSALD +E+ VQ LD+ A+ RT ++VAHRL T+RN D Sbjct: 36 YGIFYYTQGVDLLLLITGTVAAVIHGAGFPLLAIVLGGMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVVKYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYMGIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSGSTSLGGALPHLASFGTARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDKIALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYENIKMGNEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNPKILLLDEATSALDTEAEREVQGALDQ--AQAGRTTIIVAHRLSTIRNVD 596 HSP 2 Score: 276.944 bits (707), Expect = 1.247e-80 Identity = 177/535 (33.08%), Postives = 286/535 (53.46%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFA---ILSSCTFISGFIQMVT-ISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIP--IMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEK------EVKR--YSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG-KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G+ P+ L++ ++ N+ P D +M+ +V + +L TF GF + + +LR F LLRQ+I ++D + TG+L T+ D ++ + +L + I + G + + F GW+L+ I + +P +M F + + F K+ I+ + AG +A + + IRTV + + QE+ E R ++ NLK A T G + Q L IF + + +Y+G +F+ + + P V ++F I +GN + + + A+ AA LF +I+ I I + G+I +NV F YPTR +LQ F + GKTVA +G SG GKSTI+ LL+RFY+ G I G ++++++++ R + +V QEP LF +I ENI G + +EIV++ + +N + FI+ ++T +G++G SGGQKQRIAIA ALVR+P +LLLDEATSALD SEK+VQ+ LD A+ RT +++AHRL T++N+D Sbjct: 736 GSVTPVFALVYAEIFNVYSLPAD-------QMQANVYFWCGMFVLMGITFFVGFFTSANCLGRCGESLTMKLRFEAFKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFYYGWQLALILVVMVPLLVMGGYFEMQMRFGKQ--IRDTQLLEEAGKVASQAVEHIRTVHSLNRQEQFHFTYCEYLREPFNTNLKHAHTYGAVFAFSQSL--------IFFMYAAAFYLGSIFVNQQAMQPIDVYRVFFAISFCGQMIGNTTSFIPDVVKARLAASLLFYLIEHPTPIDSLSDSGIVKPITGNISIRNVFFNYPTRKDTKVLQGFTLDIKAGKTVALVGHSGCGKSTIMGLLERFYNQDKGMIMIDGDNIRNLNISSLREQVCIVSQEPTLFDCTIGENICYGTNRNVTYQEIVEAAKMANIHNFILGLPDGYDTHVGEKGTQLSGGQKQRIAIARALVRSPSVLLLDEATSALDTESEKIVQEALDA--AKQGRTCLVIAHRLSTIQNSD 1250
BLAST of SMED30003432 vs. Ensembl Fly
Match: Mdr50 (gene:FBgn0010241 transcript:FBtr0087537) HSP 1 Score: 401.364 bits (1030), Expect = 1.370e-125 Identity = 226/593 (38.11%), Postives = 355/593 (59.87%), Query Frame = -1 Query: 1 KEKPAKSKTDIXXXXXXXXXXXXXXSVSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVN-------LLVSPRD------LTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEG-------SYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISH-KKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1716 K+K ++D + + ++ VSY+QLFR+AT D + ++ ++S++ G P N LIF ++ N LL S + ++ +++R ++ + + ++ + + A Q +RS +F ++L Q++ W+D Q+G++ +++ +D+ +E G+++K+ F+ + +FVG ++LAF GW+LS + S+P+ L+ + + K++ Y+ A +AE LS IRTV AF + KEV Y + A+ L +KR++ G+G G++ F I+ +L ++ G+ + +G +YD GT+I +F ++++GS+ +G A P +E F AK A +F +I+++P+I+ G IEFK V+F+YPTRP V IL N + G+TVA +GPSG GKST I L+QRFYDP AG + F+GT+LKD+D+ W RS IGVV QEP LF+ SI ENI+ G+ DA EEI + +NA FI K + ++T +G+RGA SGGQKQRIAIA AL+R+P++LLLDEATSALD SE VQ L+K A RT ++VAHRL TVR AD Sbjct: 45 KKKSKHDESDASDEEDGSQYHEDVKQVSYFQLFRYATKKDRALYVIGLLSAVATGLTTPANSLIFGNLANDMIDLGGLLESGKSYRADDAISTLLLDKVRQFSLQNTYIGIIMLVCSYLSITCFNYAAHSQILTIRSKFFRSILHQDMKWYDFNQSGEVASRMNEDLSKMEDGLAEKVVMFVHYLVAFVGSLVLAFVKGWQLSLVCLTSLPLTFIAMGLVAVATSRLAKKEVTMYAGAAVVAEGALSGIRTVKAFEGEAKEVAAYKERVVAAKILNIKRNMFSGIGFGLLWFFIYASYALAFWYGVGLVIKGYHEPAYENYDAGTMITVFFSVMMGSMNIGMAAPYIEAFGIAKGACAKVFHIIEQIPEINPIDGEGKKLNEPLTTIEFKEVEFQYPTRPEVSILNKLNLKIHRGQTVALVGPSGCGKSTCIQLVQRFYDPQAGNLLFNGTNLKDLDINWLRSRIGVVGQEPILFATSIYENIRYGREDATREEIEAAAAAANAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIARALIRDPEILLLDEATSALDTASEAKVQAALEKVSA--GRTTIIVAHRLSTVRRAD 635 HSP 2 Score: 283.878 bits (725), Expect = 6.217e-83 Identity = 172/526 (32.70%), Postives = 277/526 (52.66%), Query Frame = -1 Query: 1 VGAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQ--TGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVI-GFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFY--GDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGK--MDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1557 +G A P+ ++F ++ +L S +D E + F I I+ F+Q+ + R + RLR F A+LRQE+ WFD + TG L +L+ D +++ ++ +Q IS+ I L+ W L + P + F + + K ++ K +A E++S+IRTV + +E + Y L A + + + +GL G+ F + +YY I+ G G V ++ +++G+ ++ NA+ N +AA +F + R P I + GV + ++ G + F V F YPTR + +L+ + G+ +A +GPSG GKST I L+QRFYD G D++++ +T R+ +G+V QEP LF +I+ENI G + ++EI+ + + SN +EFI ++T +G++GA SGGQKQRIAIA AL+RNP+++LLDEATSALD SEK+VQ LD +EG RT + +AHRL TV ++D Sbjct: 756 MGCAMPIFAVLFGSILQIL-SVKDNDQYVRENSNQYSLYFLIAGIVVGIATFLQIYFFGIAGERLTERLRGLMFEAMLRQEVAWFDDKANGTGSLCARLSGDAAAVQGATGQRIGTIVQSISTLALGIALSMYYEWSLGLVALAFTPFILIAFYMQRTLMAKENMGSAKTMENCTKLAVEVVSNIRTVASLGREEMFHQNYIGMLIPAVEISKRNTHFRGLVYGLARSLMFFAYAACMYYGTWCVIHRGIL-FGDVFKVSQALIMGTASIANALAFAPNMQKGVSAAKTIFTFLRRQPSIVDRP-GVSRDPWHSEGYVRFDKVKFSYPTRSEIQVLKGLELAVSKGQKIALVGPSGCGKSTCIQLIQRFYDVDEGATLIDECDVRNVSMTNLRNQLGIVSQEPILFDRTIRENISYGDNARNVTDQEIISACKKSNIHEFIANLPLGYDTRMGEKGAQLSGGQKQRIAIARALIRNPKIMLLDEATSALDAESEKVVQDALDAA-SEG-RTTISIAHRLSTVVHSD 1276
BLAST of SMED30003432 vs. Ensembl Fly
Match: Mdr49 (gene:FBgn0004512 transcript:FBtr0087801) HSP 1 Score: 363.229 bits (931), Expect = 1.648e-111 Identity = 212/580 (36.55%), Postives = 327/580 (56.38%), Query Frame = -1 Query: 1 SYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLV---------SP----------RDLTMTFSERMRPSVIK----FAILSSCTFISGFIQMVTISLTAAR-----QSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGS------YDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1635 SY+ LFR++T + +++V ++ + A P ++I+ + +LLV SP + LT E ++I F I S ++ F+ ++T+++ A Q R+R + A+LRQ+I W+D +K+T+D++ ++ GI +K+ + I +FV I+ AF GWKL+ + +P + S++ + K++K+YS A + EE+ S IRTV AFS QEKE +R+ L AE G K+ + G+G+ + I+ +L + G+ I + Y P ++ + +++G+ LG A P +E A AA LF +IDR Q+ + G PE+ G I F+ + F YP RP V IL+ + G+TVAF+G SG GKST+I L+QRFYDP AG + G DL+ +++ W RS IGVV QEP LF+ +I ENI+ G+ A +I K+ + +N ++FI + + ++T +G++GA SGGQKQRIAIA ALVR PQ+LLLDEATSALD SEK VQ L+ +A T ++VAHRL T+ NAD Sbjct: 30 SYFDLFRYSTRCERFLLVVSLLVATAASAFIPYFMIIYGEFTSLLVDRTVGVGTSSPAFALPMFGGGQQLTNASKEENNQAIIDDATAFGIGSLVGSVAMFL-LITLAIDLANRIALNQIDRIRKLFLEAMLRQDIAWYDTSSGSNFASKMTEDLDKLKEGIGEKIVIVVFLIMTFVIGIVSAFVYGWKLTLVVLSCVPFIIAATSVVARLQGSLAEKELKSYSDAANVVEEVFSGIRTVFAFSGQEKEKERFGKLLIPAENTGRKKGLYSGMGNALSWLIIYLCMALAIWYGVTLILDERDLPDRVYTPAVLVIVLFAVIMGAQNLGFASPHVEAIAVATAAGQTLFNIIDRPSQVDPMDEKGNRPENTAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASGCGKSTLIQLMQRFYDPEAGSVKLDGRDLRTLNVGWLRSQIGVVGQEPVLFATTIGENIRYGRPSATQADIEKAARAANCHDFITRLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQPQVLLLDEATSALDPTSEKRVQSALE--LASQGPTTLVVAHRLSTITNAD 606 HSP 2 Score: 271.937 bits (694), Expect = 1.151e-78 Identity = 176/526 (33.46%), Postives = 283/526 (53.80%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQT--GQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAV---PMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG---KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GA FPL L F D +L S D + +E ++ S+I F + + +Q + + + RLR F ++ Q+I +FD ++ G L ++L D +++ ++ +Q +++ V +++ F W+ + + +++P++ + L FI K + K + A +A E +++IRTV + + + +Y + + ++ +GL + F + Y G + + E + +I++ ++ GS LG A+ P + + I + LF+ P + + +S GDI ++NV FEYPTR G PILQ N T+ TVA +GPSGSGKST + LL R+YDP++G ++ SG + L RS +G+V QEP LF +I ENI G + D +EI+++ + SN + FI Q ++T LG + + SGGQKQRIAIA ALVRNP++L+LDEATSALD SEK+VQ+ LD+ A RT + +AHRL TVRNAD Sbjct: 746 GATFPLWGLFFGDFFGIL-SDGDDDVVRAEVLKISMI-FVGIGLMAGLGNMLQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVGALCSRLASDCSNVQGATGARVGTMLQAVATLVVGMVVGFVFSWQQTLLTLVTLPLVCLSVYLEGRFIMKSAQKAKASIEEASQVAVEAITNIRTVNGLCLERQVLDQYVQQIDRVDIACRRKVRFRGLVFALGQAAPFLAYGISMYYGGILVAEERMNYEDIIKVAEALIFGSWMLGQALAYAPNVNDAILSAGRLMDLFKRTSTQPNPPQSPYNTVEKS-EGDIVYENVGFEYPTRKGTPILQGLNLTIKKSTTVALVGPSGSGKSTCVQLLLRYYDPVSGSVNLSGVPSTEFPLDTLRSKLGLVSQEPVLFDRTIAENIAYGNNFRDDVSMQEIIEAAKKSNIHNFISALPQGYDTRLG-KTSQLSGGQKQRIAIARALVRNPKILILDEATSALDLESEKVVQQALDE--ARSGRTCLTIAHRLTTVRNAD 1265
BLAST of SMED30003432 vs. Ensembl Fly
Match: Mdr65 (gene:FBgn0004513 transcript:FBtr0077011) HSP 1 Score: 344.739 bits (883), Expect = 8.816e-105 Identity = 187/490 (38.16%), Postives = 282/490 (57.55%), Query Frame = -1 Query: 1 IKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEG------SYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS--HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1446 I I S FISG + ++ A RQ R+R F++++RQ+I W D + DDVE I GIS+K+ F+ + F+ + ++F+ GWKL+ S IP++ + F K + ++ ++Y+ AG +AEEILSSIRTVV+F ++ EV+RY + L A + GL V+ ++ + ++ G+ I + Y P ++ F I++G+ + P LE+F TA+ A LF+VID +I ++ GD+EF++V F YP+RP V + + N + G+TVA +G SG GKST + LLQRFYDP+ G + D++ ++ W RS+I VV QEP LF G+I +NI GK A +EI + + A+EFI + + + +G+RG+ SGGQKQRIAIA AL++NP++LLLDEATSALD SEK VQ+ LD +A RT ++V+HRL +R AD Sbjct: 122 ILLTIASVVMFISGIFSVDVFNMVALRQVTRMRIKLFSSVIRQDIGWHDLASKQNFTQSMVDDVEKIRDGISEKVGHFVYLVVGFIITVAISFSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQESYAGAGNLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKASQWKGAFSGLSDAVLKSMLYLSCAGAFWYGVNLIIDDRNVENKEYTPAILMIAFFGIIVGADNIARTAPFLESFATARGCATNLFKVIDLTSKIDPLSTDGKLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQKEIEAAATQAGAHEFITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALD--LASKGRTTIVVSHRLSAIRGAD 609 HSP 2 Score: 287.73 bits (735), Expect = 2.464e-84 Identity = 179/535 (33.46%), Postives = 284/535 (53.08%), Query Frame = -1 Query: 1 VGAAFPLNVLIFRDVVNLLV--SPRDLTMTFSERMRPSVIKFAILSSCTFISG---FIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQT--GQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESF------YGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLK-DIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1557 VG +P +IF + L P D R +V+ +A L F++G F+Q + + R+R+ FNA++ QE+ WFD + G L +L+ + I+ I L+ IQ +S+F+ + +A WKL+ + + PI+ + L + +++ + A IA E +++IRTV + ++ Y+ ++ E L ++ +G+ + + + F ++ G + + EG +I++ T++ GS+ L ++ F A A + LFQ++DR P+I G I + + + ++ + F YPTRP IL + + G+TVA +G SG GKST + LLQR+YDP G I D++ D+ L R+ +G+V QEP LF SI ENI G + EI+ + + +NA+ FI+ ++T +G RG SGGQKQRIAIA ALVRNP++LLLDEATSALD SE+LVQ+ LD T G RT +++AHRL TV+NAD Sbjct: 742 VGFLYPAFAVIFGEFYAALAEKDPEDALR------RTAVLSWACLG-LAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGALSARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVGSVILEAKMMSNAVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEIQRVEVLIRQKLRWRGVLNSTMQASAFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLAQSLAFTPAFSAALIAGHRLFQILDRKPKI-QSPMGTIKNTLAKQLNLFEGVRYRGIQFRYPTRPDAKILNGLDLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLTLDGVRTKLGIVSQEPTLFERSIAENIAYGDNRRSVSMVEIIAAAKSANAHSFIISLPNGYDTRMGARGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALD-TACSG-RTCIVIAHRLSTVQNAD 1266
BLAST of SMED30003432 vs. Ensembl Fly
Match: CG10226 (gene:FBgn0035695 transcript:FBtr0077012) HSP 1 Score: 334.724 bits (857), Expect = 4.057e-101 Identity = 198/584 (33.90%), Postives = 315/584 (53.94%), Query Frame = -1 Query: 4 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVS------PRDLTMTFS-----------------ERMRPSVIKFAILSSCTF----ISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMG--LLFIY--------EGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS--HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNA 1638 VSY +LFR+ G D L+++ +++ FP+ ++++ ++V + + +T+ S + +R + F IL + SG + + A + + R+R +F A LRQEI W D + ++TD++E I SGI++ L +++ + + ++L+F GWKL+ IP+ S + H+ K + ++ +Y A + EE++ +IRTVVAF + E RY LK A G + GL V+ +F G+ ++ G L+ Y E Y P V+ + I++ + + P LE F A+ +A + VIDR I K ++ G +EF++V F YP R V +L+ N + G+TVA +GPSG GKST I LLQRFYDP+ G++ G D++ ++ W RS+I VV QEP LF GSI ENI+ GK +A +E+ + + +NA++FI+ + ++T + ++G SGGQ+QRIAIA AL++ P++LLLDEATSALD SEKLVQ LDK A RT ++V+HRL +R+A Sbjct: 36 VSYTELFRYIAGWDYLVLLSGFVAAFLQSLVFPIAIVVYSELVAMFIERTLGQGTSSVTIGLSLFGGGKILTNASYEENMQELRKDSVSFGILMTLNTLLMLFSGVYYVDAFNRLALKLTVRMRREFFKATLRQEIGWHDMAKDQNFAVRITDNMEKIRSGIAENLGHYVEIMCDVIISVVLSFIYGWKLALAIVFYIPLTLVVNSAVAHYQGKLTGQEQSSYVRASSVVEEVIGAIRTVVAFGGERSESLRYDSLLKPALKAGKWKGAFSGLSDTVMKAMLFITGAGSFWYGANLILYYRDPSIPIDEREYTPAVVMIVISGIIVSANQISRTSPFLETFAMARGSASAILDVIDRTSLIDPLSKAGKILNYGLKGAVEFRDVFFRYPAREDVIVLRGLNVVVEEGQTVALVGPSGCGKSTCIQLLQRFYDPVFGQVLLDGEDVRKYNIKWLRSNIAVVGQEPVLFQGSIGENIRHGKPEATQKEVEDAAKAANAHDFIIALHKGYDTDISEKGVQLSGGQRQRIAIARALIQQPKILLLDEATSALDYHSEKLVQAALDK--ACKGRTTLVVSHRLSAIRHA 617 HSP 2 Score: 285.804 bits (730), Expect = 1.625e-83 Identity = 180/546 (32.97%), Postives = 287/546 (52.56%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISG----FIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQT--GQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQE-------KEVKRYSHNLKEAETLGVKRSICQGLGSGVI--GFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYG----------DIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLK-DIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKM--DAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G P+ ++ ++ L P D E + AI+S I+ +IQ +L + R+RS F ++ QE+ WFD+++ G L +L+ D S++ I L+ IQ ++F+ I +AF W+L+ I + P M + F +K ++K+ + IA E ++ IRTV +E KEV+RY H + R + LG ++ G+ + +L Y G +G T+++I T++ G L ++ F A +A ++++IDR PQI + I ++ G + ++ ++F YP+RP + +LQNFN + G+TVA +G SGSGKST + LL R+YDP G+I + D+DL R +G+V QEP LF SI +NI G ++I+++ + +NA+EFIM +++T LG +G SGGQKQRIAIA A+VRNP++LLLDEATSALD SE++VQ+ LD + RT +++AHRL T++NA+ Sbjct: 755 GVTMPVFSVVLAELYGSLAKPTD------EEVLEQSASMAIISLVIGIAAGVVCYIQTFFFNLAGVWLTTRMRSKTFRCIMNQEMGWFDRKENSIGALSARLSGDAASVQGAIGFPLSNIIQAFTNFICSIAIAFPYSWELALICLSTSPFMVASIVFEARFGEKSALKEKEVLEETSRIATETITQIRTVAGLRREEELIKIYDKEVERYRHQILSRLKW---RGLVNSLGKSLMFFGYAV----TLTY--GGHMCADGKIKFETIMKISNTMLYGLFILAQSLAFTPAFNAALLSANRMYEIIDRKPQIQSPESFEIQQNGNGTAYKTNVVQQGVSYRGLNFSYPSRPHIKVLQNFNLDINQGQTVALVGASGSGKSTCVQLLMRYYDPDEGKILIDQESIHHDMDLKTLRRRLGIVSQEPSLFEKSIADNIGYGDTSRQVPMQQIIEAAKMANAHEFIMSLPAQYDTVLGSKGTQLSGGQKQRIAIARAMVRNPKILLLDEATSALDFQSERVVQQALDSACS--GRTCIVIAHRLSTIQNAN 1283
BLAST of SMED30003432 vs. Ensembl Fly
Match: CG10226 (gene:FBgn0035695 transcript:FBtr0332068) HSP 1 Score: 331.643 bits (849), Expect = 2.003e-100 Identity = 177/463 (38.23%), Postives = 267/463 (57.67%), Query Frame = -1 Query: 4 RLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMG--LLFIY--------EGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS--HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNA 1356 R+R +F A LRQEI W D + ++TD++E I SGI++ L +++ + + ++L+F GWKL+ IP+ S + H+ K + ++ +Y A + EE++ +IRTVVAF + E RY LK A G + GL V+ +F G+ ++ G L+ Y E Y P V+ + I++ + + P LE F A+ +A + VIDR I K ++ G +EF++V F YP R V +L+ N + G+TVA +GPSG GKST I LLQRFYDP+ G++ G D++ ++ W RS+I VV QEP LF GSI ENI+ GK +A +E+ + + +NA++FI+ + ++T + ++G SGGQ+QRIAIA AL++ P++LLLDEATSALD SEKLVQ LDK A RT ++V+HRL +R+A Sbjct: 43 RMRREFFKATLRQEIGWHDMAKDQNFAVRITDNMEKIRSGIAENLGHYVEIMCDVIISVVLSFIYGWKLALAIVFYIPLTLVVNSAVAHYQGKLTGQEQSSYVRASSVVEEVIGAIRTVVAFGGERSESLRYDSLLKPALKAGKWKGAFSGLSDTVMKAMLFITGAGSFWYGANLILYYRDPSIPIDEREYTPAVVMIVISGIIVSANQISRTSPFLETFAMARGSASAILDVIDRTSLIDPLSKAGKILNYGLKGAVEFRDVFFRYPAREDVIVLRGLNVVVEEGQTVALVGPSGCGKSTCIQLLQRFYDPVFGQVLLDGEDVRKYNIKWLRSNIAVVGQEPVLFQGSIGENIRHGKPEATQKEVEDAAKAANAHDFIIALHKGYDTDISEKGVQLSGGQRQRIAIARALIQQPKILLLDEATSALDYHSEKLVQAALDK--ACKGRTTLVVSHRLSAIRHA 503 HSP 2 Score: 285.419 bits (729), Expect = 9.465e-84 Identity = 181/545 (33.21%), Postives = 287/545 (52.66%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRD---LTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQT--GQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQE-------KEVKRYSHNLKEAETLGVKRSICQGLGSGVI--GFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYG----------DIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLK-DIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKM--DAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G P+ ++ ++ L P D L + S + VI A C + F + + LT R+RS F ++ QE+ WFD+++ G L +L+ D S++ I L+ IQ ++F+ I +AF W+L+ I + P M + F +K ++K+ + IA E ++ IRTV +E KEV+RY H + R + LG ++ G+ + +L Y G +G T+++I T++ G L ++ F A +A ++++IDR PQI + I ++ G + ++ ++F YP+RP + +LQNFN + G+TVA +G SGSGKST + LL R+YDP G+I + D+DL R +G+V QEP LF SI +NI G ++I+++ + +NA+EFIM +++T LG +G SGGQKQRIAIA A+VRNP++LLLDEATSALD SE++VQ+ LD + RT +++AHRL T++NA+ Sbjct: 641 GVTMPVFSVVLAELYGSLAKPTDEEVLEQSASMAIISLVIGIAAGVVCYIQTFFFNLAGVWLTT-----RMRSKTFRCIMNQEMGWFDRKENSIGALSARLSGDAASVQGAIGFPLSNIIQAFTNFICSIAIAFPYSWELALICLSTSPFMVASIVFEARFGEKSALKEKEVLEETSRIATETITQIRTVAGLRREEELIKIYDKEVERYRHQILSRLKW---RGLVNSLGKSLMFFGYAV----TLTY--GGHMCADGKIKFETIMKISNTMLYGLFILAQSLAFTPAFNAALLSANRMYEIIDRKPQIQSPESFEIQQNGNGTAYKTNVVQQGVSYRGLNFSYPSRPHIKVLQNFNLDINQGQTVALVGASGSGKSTCVQLLMRYYDPDEGKILIDQESIHHDMDLKTLRRRLGIVSQEPSLFEKSIADNIGYGDTSRQVPMQQIIEAAKMANAHEFIMSLPAQYDTVLGSKGTQLSGGQKQRIAIARAMVRNPKILLLDEATSALDFQSERVVQQALDSACS--GRTCIVIAHRLSTIQNAN 1169
BLAST of SMED30003432 vs. Ensembl Zebrafish
Match: abcb4 (ATP-binding cassette, sub-family B (MDR/TAP), member 4 [Source:ZFIN;Acc:ZDB-GENE-080204-52]) HSP 1 Score: 451.44 bits (1160), Expect = 1.168e-144 Identity = 236/561 (42.07%), Postives = 350/561 (62.39%), Query Frame = -1 Query: 1 QLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVS------------------PRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1626 +LFR+A ID+L++++ +I S+ GA PL V++F D+ + V P +T E+M I ++I+ ++ ++Q+ +L A RQ ++LR +F+++++QEI WFD +TGQL T+LTDDV I GI DKL IQ +++F+ II+ F GWKL+ + P++ + +++ + ++ K+ AY+ AG +AEE+LSSIRTV AF Q+KE+KRY NL++A+ +GV+++I + G F I+ +L ++ G I G Y G ++ IF ++IG+ LG P ++ F +A+ AA+ +FQ+ID P+I S + G + G+IEFKN+ F YP+R V +L N + G+T+A +G SG GKST I LLQRFYDP G +S G D++ +++ R IGVV QEP LF+ +I ENI+ G+ D +EI ++ +++NAY FIMK KF T +GDRG SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK RT ++VAHRL T+RNAD Sbjct: 43 ELFRYADSIDILLMMLGLIMSMANGAVLPLMVIVFGDMTDSFVDDTLLDNLKNITLPPNFTFPETSNITLGEKMTTHAIYYSIMGFVVLVAAYMQVAFWTLAAGRQVKKLRKIFFHSIMKQEIGWFDVNETGQLNTRLTDDVYKINEGIGDKLGMLIQNLTTFIVGIIIGFAKGWKLTLVILAVSPLLGISAAVIGKVMTTFTSKEQTAYAKAGAVAEEVLSSIRTVFAFGGQKKEIKRYHKNLEDAKNVGVRKAITVNIAMGFTFFMIYMSYALAFWYGSTLILGGEYTIGMLLTIFFAVLIGAFGLGQTSPNIQTFSSARGAAHKVFQIIDHEPKINSFSEEGYKLDVVKGNIEFKNIHFRYPSRDDVKVLNGMNLKVMSGQTIALVGSSGCGKSTTIQLLQRFYDPQEGSVSIDGHDIRSLNVRGLRELIGVVSQEPVLFATTIAENIRYGRQDVTQDEIEQAAREANAYNFIMKLPDKFETLVGDRGTQMSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAALDKV--RLGRTTIVVAHRLSTIRNAD 601 HSP 2 Score: 327.405 bits (838), Expect = 2.056e-98 Identity = 192/534 (35.96%), Postives = 291/534 (54.49%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNL--------KEAETLGVKRSICQGLGSGVIGFT---IFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHK-KHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G P +IF ++ + P D + +R + FA + +F + F+Q + RLR FNA++RQ++ W+D K G L T+L D ++ +LA Q +++ I+++F GW+L+ + +PIMA ++ + + +++K K AG IA E + ++RTVV+ + + K Y NL K+A G+ S Q + I F F GS + L+ +EG V + +V G++A+G A N+ AK +A + +I+R P I + + G P+ F G++ F++V F+YP+RP VP+LQ + G+T+A +G SG GKST I LL+RFYDP G + D K +++ W RS IG+V QEP LF S+ ENI G + EEIV++ + +N + FI Q++ T GD+G SGGQKQRIAIA A++RNP++LLLDEATSALD SEK+VQ LDK A RT ++VAHRL T++NAD Sbjct: 721 GGMQPAFAVIFSKIIAVFAEP-DQNLV-RQRCDLYSLLFAGIGVLSFFTLFLQGFCFGKAGELLTMRLRFKAFNAMMRQDLAWYDDTKNSVGALTTRLAADTAQVQGATGVRLATLAQNVANLGTAIVISFVYGWQLTLLILSIVPIMAVAGAIQMKLLAGHALKDKKELEQAGKIATEAIENVRTVVSLTRESKFESLYEENLIVPYKNAKKKAHVFGLTFSFSQAM----IYFAYAGCFKFGSWLIEQKLM-TFEG------VFLVISAVVYGAMAVGEANSFTPNYAKAKMSASHVLMLINRAPAIDNSSEDGDKPDKFEGNVGFEHVYFKYPSRPDVPVLQGLKLRVKKGQTLALVGSSGCGKSTTIQLLERFYDPQQGRVMLDDNDAKQLNIHWLRSQIGIVSQEPVLFDCSLAENIAYGDNSREVDQEEIVEAAKAANIHSFIENLPQRYQTQAGDKGTQLSGGQKQRIAIARAILRNPKVLLLDEATSALDTESEKIVQDALDK--ASKGRTCIIVAHRLSTIQNAD 1239
BLAST of SMED30003432 vs. Ensembl Zebrafish
Match: abcb5 (ATP-binding cassette, sub-family B (MDR/TAP), member 5 [Source:ZFIN;Acc:ZDB-GENE-030131-6414]) HSP 1 Score: 439.499 bits (1129), Expect = 1.188e-139 Identity = 238/604 (39.40%), Postives = 366/604 (60.60%), Query Frame = -1 Query: 1 KEKPAKSKTDIXXXXXXXXXXXXXXSVSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSP--------------RDLTMTFSER-----------MRPSVIK----FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMG--LLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRV-PQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1716 +E P+ SK + K K K M+SV ++QLFR+AT ++ ++++ ++ + G A PL ++F + + V + T T + + P + K F + + G Q++ LTAA+Q++R+R YF+A+L Q++ WFD G+L +LTDD+ +I G+ DK+A F+Q SF+ +++ F GWKL+ + P++A + ++ + + K++ AY+ AG +AEEIL +IRTVVAF+ Q+K V++Y NL EA+ GVK++I + G+ F +F +L ++ G L +Y G V+ +F +++IG+ +LG P LE A+ AAY +++ ID P S K G P+ GDIEFKN++F YP+R V ILQ + +P+GKT+A +G SG GKST I LLQRFYDP +GE++ G D++ +++ W R ++G+V QEP LF +I ENI+ G+ DA + +I ++ +++NAY+FI K K NT +G+RGA SGGQKQRIAIA ALV+NP++LLLDEATSALD SE +VQ LDK A RT +++AHRL T+R+AD Sbjct: 41 EEPPSDSKHKGKKGKNSKDNKEPMKSVGFFQLFRYATCPEVFLMLIGLLCAAAHGVALPLMCVVFGQMTDSFVQSGQTYNLTGFNGNFTSNFTFTLNNTSTCLAGSPEIGIEPKMTKQAYFFIGIGGAVLVLGTFQVMLFLLTAAKQTKRIRQKYFHAILHQQMSWFDTHPIGELNIRLTDDINTINDGLGDKIAVFVQFFCSFISGLVIGFVFGWKLTLVILAVSPLLAGSAAVWSKILASLTSKELTAYAKAGAVAEEILVAIRTVVAFNGQKKAVEKYEKNLVEAKDFGVKKAISTNVSMGLTQFIVFATYALAFWYGTKLSVDEPENYTIGRVLTVFFSVMIGTFSLGQGAPNLEAIAKARGAAYEVYKTIDMPRPIDSSSKEGHKPDRVRGDIEFKNINFNYPSRKDVTILQGMSLKVPHGKTIALVGASGCGKSTTIQLLQRFYDPDSGEVTLDGHDIRSLNVRWLRENMGIVSQEPVLFGTTIAENIRYGREDATDADIEQAIKEANAYDFISKLPDKLNTMVGERGAQLSGGQKQRIAIARALVKNPKILLLDEATSALDTQSESIVQAALDK--ARAGRTTIVIAHRLSTIRSAD 642 HSP 2 Score: 321.627 bits (823), Expect = 3.735e-96 Identity = 185/532 (34.77%), Postives = 289/532 (54.32%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSP-----RDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQT--GQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQ----GLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGK--MDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GA +P ++F ++ + P R TM FS + + ++ F++ F Q + + RLRS F A++RQEI WFD G L TKL D ++ +L I + + +I+AF W+L+ + +P + + + ++ K A ++G I+ E + + +TVVA + ++ + H ++ + K S+C+ G+ + + V + ++ G I + V +F IV ++ +G + +F AKAAA + Q++++ P+I + + G P +F G+I+FK+V F YPTRP V +LQ N ++ G+T+A +G SG GKST I LL+RFYDP G++ G D K ++L W R+ +G+V QEP LF +I ENIQ G EEI ++ + +N + FI+ K+NT +GD+G SGGQKQRIAIA ALVR P+LLLLDEATSALD SEK+VQ LD+ A RT +++AHRL T++NAD Sbjct: 783 GAVYPCVAILFAKIIGVFAEPDPEVKRQKTMMFS-------LLYLLIGVVAFLTYFFQGFMFGKSGELLTMRLRSQAFKAIVRQEIGWFDDNNNAVGILTTKLATDASLVKGAAGSRLGLATNTICALLIAVIVAFVFCWQLTLLILACVPFLTGANFIQLRATAGHTSKDQSALEMSGKISTETVENFKTVVALTREDV----FFHKFIDSLSTPYKASLCKAPIYGITFALAQAIPYLVNAAIFRFGAWLIAHCYTEYENVFLVFSVIVFAAMNIGQSSSFAPDFAKAKAAAGRIIQLLEKKPEIDIYDESGERPSTFSGNIDFKDVQFSYPTRPNVKVLQGLNVSVRQGQTLALVGSSGCGKSTTIQLLERFYDPAGGQVLVDGRDSKSVNLAWLRTQMGLVSQEPILFDCTISENIQYGDNSRTVTQEEIEEAAKKANIHNFILTLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRKPKLLLLDEATSALDTESEKIVQAALDE--ARLGRTCIVIAHRLTTIQNAD 1301
BLAST of SMED30003432 vs. Ensembl Zebrafish
Match: abcb5 (ATP-binding cassette, sub-family B (MDR/TAP), member 5 [Source:ZFIN;Acc:ZDB-GENE-030131-6414]) HSP 1 Score: 439.884 bits (1130), Expect = 1.297e-139 Identity = 237/604 (39.24%), Postives = 366/604 (60.60%), Query Frame = -1 Query: 1 KEKPAKSKTDIXXXXXXXXXXXXXXSVSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSP--------------RDLTMTFSER-----------MRPSVIK----FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEG--SYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRV-PQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1716 +E P+ SK + K K K M+SV ++QLFR+AT ++ ++++ ++ + G A PL ++F + + V + T T + + P + K F + + G Q++ LTAA+Q++R+R YF+A+L Q++ WFD G+L +LTDD+ +I G+ DK+A F+Q SF+ +++ F GWKL+ + P++A + ++ + + K++ AY+ AG +AEEIL +IRTVVAF+ Q+K V++Y NL EA+ GVK++I + G+ F +F +L ++ G + +Y G V+ +F +++IG+ +LG P LE A+ AAY +++ ID P S K G P+ GDIEFKN++F YP+R V ILQ + +P+GKT+A +G SG GKST I LLQRFYDP +GE++ G D++ +++ W R ++G+V QEP LF +I ENI+ G+ DA + +I ++ +++NAY+FI K K NT +G+RGA SGGQKQRIAIA ALV+NP++LLLDEATSALD SE +VQ LDK A RT +++AHRL T+R+AD Sbjct: 53 EEPPSDSKHKGKKGKNSKDNKEPMKSVGFFQLFRYATCPEVFLMLIGLLCAAAHGVALPLMCVVFGQMTDSFVQSGQTYNLTGFNGNFTSNFTFTLNNTSTCLAGSPEIGIEPKMTKQAYFFIGIGGAVLVLGTFQVMLFLLTAAKQTKRIRQKYFHAILHQQMSWFDTHPIGELNIRLTDDINTINDGLGDKIAVFVQFFCSFISGLVIGFVFGWKLTLVILAVSPLLAGSAAVWSKILASLTSKELTAYAKAGAVAEEILVAIRTVVAFNGQKKAVEKYEKNLVEAKDFGVKKAISTNVSMGLTQFIVFATYALAFWYGTKLSVDEPENYTIGRVLTVFFSVMIGTFSLGQGAPNLEAIAKARGAAYEVYKTIDMPRPIDSSSKEGHKPDRVRGDIEFKNINFNYPSRKDVTILQGMSLKVPHGKTIALVGASGCGKSTTIQLLQRFYDPDSGEVTLDGHDIRSLNVRWLRENMGIVSQEPVLFGTTIAENIRYGREDATDADIEQAIKEANAYDFISKLPDKLNTMVGERGAQLSGGQKQRIAIARALVKNPKILLLDEATSALDTQSESIVQAALDK--ARAGRTTIVIAHRLSTIRSAD 654 HSP 2 Score: 322.398 bits (825), Expect = 2.423e-96 Identity = 187/533 (35.08%), Postives = 290/533 (54.41%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSP-----RDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQT--GQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTI-----FTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GA +P ++F ++ + P R TM FS + + ++ F++ F Q + + RLRS F A++RQEI WFD G L TKL D ++ +L I + + +I+AF W+L+ + +P + + + ++ K A ++G I+ E + + +TVVA + ++ + H ++ + K S+C+ G I F + + V + ++ G I + V +F IV ++ +G + +F AKAAA + Q++++ P+I + + G P +F G+I+FK+V F YPTRP V +LQ N ++ G+T+A +G SG GKST I LL+RFYDP G++ G D K ++L W R+ +G+V QEP LF +I ENIQ G EEI ++ + +N + FI+ K+NT +GD+G SGGQKQRIAIA ALVR P+LLLLDEATSALD SEK+VQ LD+ A RT +++AHRL T++NAD Sbjct: 795 GAVYPCVAILFAKIIGVFAEPDPEVKRQKTMMFS-------LLYLLIGVVAFLTYFFQGFMFGKSGELLTMRLRSQAFKAIVRQEIGWFDDNNNAVGILTTKLATDASLVKGAAGSRLGLATNTICALLIAVIVAFVFCWQLTLLILACVPFLTGANFIQLRATAGHTSKDQSALEMSGKISTETVENFKTVVALTREDV----FFHKFIDSLSTPYKASLCKAPIYG-ITFALAQAIPYLVNAAIFRFGAWLIAHCYTEYENVFLVFSVIVFAAMNIGQSSSFAPDFAKAKAAAGRIIQLLEKKPEIDIYDESGERPSTFSGNIDFKDVQFSYPTRPNVKVLQGLNVSVRQGQTLALVGSSGCGKSTTIQLLERFYDPAGGQVLVDGRDSKSVNLAWLRTQMGLVSQEPILFDCTISENIQYGDNSRTVTQEEIEEAAKKANIHNFILTLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRKPKLLLLDEATSALDTESEKIVQAALDE--ARLGRTCIVIAHRLTTIQNAD 1313
BLAST of SMED30003432 vs. Ensembl Zebrafish
Match: abcb11a (ATP-binding cassette, sub-family B (MDR/TAP), member 11a [Source:ZFIN;Acc:ZDB-GENE-050517-13]) HSP 1 Score: 407.527 bits (1046), Expect = 1.051e-127 Identity = 239/621 (38.49%), Postives = 359/621 (57.81%), Query Frame = -1 Query: 1 YNVEEANFANSILKEKPAKSKTDIXXXXXXXXXXXXXXSVSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVS------------------------------PRDLTMTFSERMRPSVIKFAI----LSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEG-SYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1755 YN E+A+ N +K+K K+ T V ++QLFRF+T ++L+++V S+ GAA PL +L++ + N V P + T+ + + FA+ + I F Q+ AARQ +R+R YF ++ EI WFD G+L T+++DD+ I + I+D+++ FI++IS+F+ ++ F GWKL+ + P++ LM + + + +++KAY+ AG +A+E+LSSIRTV AF + KE +RY NL +A+ G+K+ + G+ G + IF +L ++ G + E PG ++Q+F ++IG++ LG A P LE F + +AAA +F IDR P+I G + GDIEF +V+F YP+RP V IL + N + G+T AF+GPSGSGK+T I L+QRFYDP G +S G D++ +++ W RS IGVV+QEP LF+ +I ENI+ G+ +EI+++ + +NAY FIM Q F+T +G+ G SGGQKQRIAIA ALVRNP++LLLD ATSALDN SE +VQ+ LDK A RT + +AHRL T+RNAD Sbjct: 17 YNAEDADLKNGEVKKKE-KAPT-----------------VGFFQLFRFSTWREVLMMVVGSFCSLVHGAATPLMLLVYGMMTNTFVEYEVEILELTDPNKTCINNTISWMNGSAVQRPDNTTIYCGVDIEAEMTNFALYYIGIGVGVLILSFFQITFWVSAAARQIQRIRKTYFRKIMCMEIGWFDCNSVGELNTRMSDDINKINNAIADQVSIFIERISTFIFGFMVGFIGGWKLTLVVIAVSPLLGLAAGLMAMAVARLTGRELKAYAKAGAVADEVLSSIRTVAAFGGEHKEAERYDRNLVQAQEWGIKKGMIIGVFQGYLWCIIFLCYALAFWFGSKLVIETQELTPGGLVQVFFGVLIGAMNLGQASPCLEAFASGRAAAKSIFDTIDREPEIDCFSDEGHTLDKVKGDIEFHSVNFNYPSRPEVKILDDLNIVVKAGETTAFVGPSGSGKTTTIQLIQRFYDPSEGMVSLDGHDIRSLNIQWLRSLIGVVEQEPVLFATTIAENIRYGRAGVTMQEIIEAAKQANAYNFIMSLPQTFDTLVGEGGGQMSGGQKQRIAIARALVRNPRILLLDMATSALDNESEAVVQEALDK--ARQGRTTISIAHRLSTIRNAD 617 HSP 2 Score: 288.115 bits (736), Expect = 3.055e-84 Identity = 175/524 (33.40%), Postives = 278/524 (53.05%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDK--QQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVY-YMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G+ P+ L+F ++ P ++ I F ++ +F S F+Q + + + +RRLR F A+L+QEI WFD G L T+L + ++ ++ + +++ I+A+ WKLS + + +P++ + + + + A AG ++ E +S+IRT+ + ++ V ++ L+ K++ G+ IF + + Y G L +EG V ++ +V + ALG A ++ AK +A LFQ++DRVP+I+ K G F G +EFK F YP+RP V +L+ ++ G+T+AF+G SG GKST + LL+RFYDP G++ G I + + RS IG+V QEP LF SI ENIQ G EEI+ + + + ++F+M K+ T +G +G+ S GQKQRIAIA A+VRNP++LLLDEATSALD SEK VQ LD+ A RT +++AHRL T+++AD Sbjct: 765 GSLNPMYALLFSQILGTFSIPDPDDQ--RRQINGICILFVVIGVVSFFSQFLQGYSFAKSGELLTRRLRKFGFQAMLKQEIGWFDDPMNSPGALTTRLATNASMVQGATGSQIGMIVNSLTNIGASFIIAYYFSWKLSLVVTCFLPLIGLSGVFQSKMLTGLANEDKTALEAAGQVSSEAMSNIRTIAGLAKEKHFVAQFEKQLQAPYKAAKKKAYVYGICFAFARCVIFMAYAASFRYGGYLVSHEG-LQYMMVFRVISALVTSATALGRASSFTPDYAKAKISAAQLFQLLDRVPKINVSKTEGQSWNDFKGKVEFKGCRFTYPSRPDVQVLRGLVVSVHPGQTLAFVGSSGCGKSTSVQLLERFYDPDEGQVLIDGRPSDSISVPFLRSQIGIVSQEPVLFDCSIAENIQYGDNSRTVSMEEIIDAAKKAYLHDFVMTLPDKYETQVGAQGSQLSRGQKQRIAIARAIVRNPKILLLDEATSALDTESEKTVQAALDE--ARQGRTCIVIAHRLSTIQSAD 1283
BLAST of SMED30003432 vs. Ensembl Zebrafish
Match: abcb11b (ATP-binding cassette, sub-family B (MDR/TAP), member 11b [Source:ZFIN;Acc:ZDB-GENE-050517-14]) HSP 1 Score: 396.741 bits (1018), Expect = 5.795e-124 Identity = 206/474 (43.46%), Postives = 304/474 (64.14%), Query Frame = -1 Query: 1 FISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGL-LFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISH-KKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1416 FI G++Q+ AARQ + +R YF ++R EI WFD G+L T+++DD+ I I+D++ FIQ+ ++FV ++ F GWKL+ + P++ LM F+ K + +++AY+ AG +A+E+LSS+RTV AF ++KEV RY NL A+ G+++ + G +G + F IF +L ++ G L + Y PGT++Q+F ++I ++ LG A P LE F + AA +F+ IDR P+I + G + GD+EF N+ F YP+RP V IL N + G+T AF+GPSG+GKST I L+QRFYDP G ++ G D++ +++ W RS IG+V+QEP LF+ +I ENI+ G+ N++I+ + +++NAY FIM QKF T +G+ G SGGQKQRIAIA ALVRNP++LLLD ATSALDN SE +VQ+ LDK RT + +AHRL T++NAD Sbjct: 95 FILGYLQISLWITAAARQIQIIRKMYFRKVMRMEIGWFDCTSVGELNTRMSDDINKINDAIADQVGIFIQRFTTFVCGFLMGFARGWKLTLVIISVSPLIGIGAGLMALFVAKLTGMELQAYAKAGAVADEVLSSVRTVAAFGGEKKEVDRYDRNLISAQQWGIRKGLIMGFFTGYMWFIIFLCYALAFWYGSSLVVDTQEYSPGTLLQVFFGVLIAALNLGQASPCLEAFAAGRGAATIIFETIDREPEIDCLSEAGYKLDKVKGDLEFHNITFHYPSRPEVKILDQLNLQVKSGETTAFVGPSGAGKSTAIQLIQRFYDPKEGMLTLDGHDIRGLNIQWLRSLIGIVEQEPVLFATTIAENIRYGRPGVSNDDIITAAKEANAYNFIMDLPQKFETLVGEGGGQMSGGQKQRIAIARALVRNPRILLLDMATSALDNESEAVVQEALDKV--RMGRTTISIAHRLSTIKNAD 566 HSP 2 Score: 277.715 bits (709), Expect = 9.802e-81 Identity = 166/485 (34.23%), Postives = 269/485 (55.46%), Query Frame = -1 Query: 1 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1440 F ++ +F + +Q S + +RRLR F A+L QEI WFD K G L T+L D ++ ++ + +++ +I++F WKL+ + +P +A + + ++ + +A AG I+ E L++IRT+ + V+ + L+ +K++ G G +F S Y G +Y V ++ IV ALG A ++ AK +A FQ++DR+P+IS + K G ++F GDIEF + F YP+RP + +L N ++ G+T+AF+G SG GKST + LL+RFYDP +G + G + I++ + RS IG+V QEP LF SI ENI+ G + + +++ + + + ++F+M +K++T +G +G+ S GQKQRIAIA A++R+P++LLLDEATSALD SEK VQ+ LDK A RT +++AHRL T++N+D Sbjct: 760 FVVVGLVSFFTQMLQGYAFSKSGELLTRRLRRLGFQAMLGQEIGWFDDRKNSPGALTTRLATDASQVQGATGSQIGMIVNSLTNIGVAVIISFYFSWKLTLVILCFLPFLALSGGFQAKMLTGFAKQDKEAMETAGQISGEALNNIRTIAGLGKERNFVEMFETQLEAPYQAALKKANVYGACYGFAQCVVFMANSASYRFGGYLVYHEGLHFSFVFRVISAIVTSGTALGRASSYTPDYAKAKISAARFFQLLDRIPKISVYSKDGQKWDNFKGDIEFIDCKFTYPSRPDIQVLNGLNVSVKPGQTLAFVGSSGCGKSTSVQLLERFYDPNSGRVLIDGRESSQINVAYLRSKIGIVSQEPILFDCSIAENIRYGDNQRELSMNDVISAAKKAQLHDFVMSLPEKYDTNVGSQGSQLSRGQKQRIAIARAIIRDPKILLLDEATSALDTESEKTVQEALDK--AREGRTCIVIAHRLSTIQNSD 1242
BLAST of SMED30003432 vs. Ensembl Xenopus
Match: mia2 (MIA SH3 domain ER export factor 2 [Source:Xenbase;Acc:XB-GENE-993630]) HSP 1 Score: 469.929 bits (1208), Expect = 1.381e-151 Identity = 240/558 (43.01%), Postives = 354/558 (63.44%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDL-----------TMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V + +FR+++ D ++++ I+SI GAA PL +++F D+ + V+ + + E+M ++ L + ++Q+ +L+A +Q +R+RSN+F+A+LRQEI WFD G+L T+LTDDV I GI DK+A +Q +++FV I+ F GWKL+ + P+M + ++ + ++ K++KAY+ AG +AEE+LSSIRTV AF Q+KE+KRY NL+EA+ +G+K++I + G I+ +L ++ G I G Y G+V+ +F ++IG+ A+G P +E F A+ AAY +F +ID P+I S K G+ P+ GDIEFKNV F YP+R + +L+ N +P GKTVA +G SG GKST + L+QRFYDP G I+ G D++ +++ + R IGVV QEP LF +I +NI+ G+ D EEI ++T+++NAY FIMK KF T +G+RG SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK A RT ++VAHRL T+RNAD Sbjct: 48 VGVFTMFRYSSTSDRILMLFGTIASISHGAALPLMMIVFGDMTDSFVNVGQVGNFSLEALINASRNLQEQMTTYAYYYSGLGFGVLLFAYVQISFWTLSAGKQIKRIRSNFFHAVLRQEIGWFDVNDAGELNTRLTDDVSKINEGIGDKIAMLLQSLTTFVTGFIIGFVKGWKLTLVILAISPVMGFSAAIWAKVLSAFTNKELKAYAKAGAVAEEVLSSIRTVFAFGGQDKEIKRYEKNLEEAKRIGIKKAITANVSIGFAFLMIYAAYALAFWYGTTLIINGGYTIGSVLTVFFAVIIGAFAVGQTSPNVEAFANARGAAYTIFNIIDNQPKIDSFSKEGLKPDKIKGDIEFKNVKFTYPSRTDIQVLKGLNLNIPSGKTVALVGSSGCGKSTTVQLIQRFYDPEEGVITLDGQDIRSLNIRYLREIIGVVSQEPILFDTTIADNIRYGREDVTMEEIERATKEANAYNFIMKLPDKFETLVGERGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESESVVQAALDK--AREGRTTIVVAHRLSTIRNAD 603 HSP 2 Score: 318.546 bits (815), Expect = 3.835e-95 Identity = 183/527 (34.72%), Postives = 286/527 (54.27%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAIL----SSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GA P +IF ++ + P + MR +++L +FI+ F+Q+ R YF +EI WFD K TG L T+L D ++ +LA Q I++ +I++F GW+L+ + +PI+A + + + ++ K K AG I+ + + +IRTVV+ + + K Y NL+ +K++ GL + ++ + + G + E P V +F IV G++ALG ++ A +A +F +++RVP I S+ K G P++ G+++F+ V F YPTRP + +LQ + ++ G+T+A +G SG GKST + LL+RFYDP GE+ G ++D+++ W R+ +G+V QEP LF SI ENI G + EI + +++N + FI K+NT +GD+G SGGQKQRIAIA ALVR P++LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 722 GATQPAFAIIFSKIIGVFAGP-------ASEMRAKSTMYSLLFLALGGISFITFFLQV------------RFGHVYFTL---KEIGWFDDTKNSTGALTTRLATDASQVQGATGSRLALLAQNIANLGTAVIISFIYGWRLTLLILAIVPIIAASALVQLKMFAGHAKKDKKELEKAGKISTDAVLNIRTVVSLTRERKFEAMYEKNLEGPYRNSIKKAHLHGLTYALSQAIMYFAYAGCFRFGAYLVAELLMTPDDVFLVFSAIVFGAMALGQTSSFAPDYTKAMISAAHIFSLLERVPLIDSYSKEGEKPQNCGGNVQFQGVQFNYPTRPDITVLQGLDISVKQGETLALVGSSGCGKSTTVSLLERFYDPFGGEVLVDGHSVRDLNIQWVRAQMGIVSQEPILFDCSIGENIAYGDNSREVTQAEIETAAKEANIHSFIDTLTDKYNTRVGDKGTQMSGGQKQRIAIARALVRKPKILLLDEATSALDTESEKVVQEALDK--ARTGRTCIVIAHRLSTIQNAD 1224
BLAST of SMED30003432 vs. Ensembl Xenopus
Match: mia2 (MIA SH3 domain ER export factor 2 [Source:Xenbase;Acc:XB-GENE-993630]) HSP 1 Score: 470.315 bits (1209), Expect = 1.460e-151 Identity = 240/558 (43.01%), Postives = 354/558 (63.44%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDL-----------TMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V + +FR+++ D ++++ I+SI GAA PL +++F D+ + V+ + + E+M ++ L + ++Q+ +L+A +Q +R+RSN+F+A+LRQEI WFD G+L T+LTDDV I GI DK+A +Q +++FV I+ F GWKL+ + P+M + ++ + ++ K++KAY+ AG +AEE+LSSIRTV AF Q+KE+KRY NL+EA+ +G+K++I + G I+ +L ++ G I G Y G+V+ +F ++IG+ A+G P +E F A+ AAY +F +ID P+I S K G+ P+ GDIEFKNV F YP+R + +L+ N +P GKTVA +G SG GKST + L+QRFYDP G I+ G D++ +++ + R IGVV QEP LF +I +NI+ G+ D EEI ++T+++NAY FIMK KF T +G+RG SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK A RT ++VAHRL T+RNAD Sbjct: 48 VGVFTMFRYSSTSDRILMLFGTIASISHGAALPLMMIVFGDMTDSFVNVGQVGNFSLEALINASRNLQEQMTTYAYYYSGLGFGVLLFAYVQISFWTLSAGKQIKRIRSNFFHAVLRQEIGWFDVNDAGELNTRLTDDVSKINEGIGDKIAMLLQSLTTFVTGFIIGFVKGWKLTLVILAISPVMGFSAAIWAKVLSAFTNKELKAYAKAGAVAEEVLSSIRTVFAFGGQDKEIKRYEKNLEEAKRIGIKKAITANVSIGFAFLMIYAAYALAFWYGTTLIINGGYTIGSVLTVFFAVIIGAFAVGQTSPNVEAFANARGAAYTIFNIIDNQPKIDSFSKEGLKPDKIKGDIEFKNVKFTYPSRTDIQVLKGLNLNIPSGKTVALVGSSGCGKSTTVQLIQRFYDPEEGVITLDGQDIRSLNIRYLREIIGVVSQEPILFDTTIADNIRYGREDVTMEEIERATKEANAYNFIMKLPDKFETLVGERGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESESVVQAALDK--AREGRTTIVVAHRLSTIRNAD 603 HSP 2 Score: 338.191 bits (866), Expect = 2.817e-102 Identity = 188/527 (35.67%), Postives = 293/527 (55.60%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAIL----SSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GA P +IF ++ + P + MR +++L +FI+ F+Q T ++RLR F ++LRQEI WFD K TG L T+L D ++ +LA Q I++ +I++F GW+L+ + +PI+A + + + ++ K K AG I+ + + +IRTVV+ + + K Y NL+ +K++ GL + ++ + + G + E P V +F IV G++ALG ++ A +A +F +++RVP I S+ K G P++ G+++F+ V F YPTRP + +LQ + ++ G+T+A +G SG GKST + LL+RFYDP GE+ G ++D+++ W R+ +G+V QEP LF SI ENI G + EI + +++N + FI K+NT +GD+G SGGQKQRIAIA ALVR P++LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 720 GATQPAFAIIFSKIIGVFAGP-------ASEMRAKSTMYSLLFLALGGISFITFFLQGFTFGKAGEILTKRLRLWSFKSMLRQEIGWFDDTKNSTGALTTRLATDASQVQGATGSRLALLAQNIANLGTAVIISFIYGWRLTLLILAIVPIIAASALVQLKMFAGHAKKDKKELEKAGKISTDAVLNIRTVVSLTRERKFEAMYEKNLEGPYRNSIKKAHLHGLTYALSQAIMYFAYAGCFRFGAYLVAELLMTPDDVFLVFSAIVFGAMALGQTSSFAPDYTKAMISAAHIFSLLERVPLIDSYSKEGEKPQNCGGNVQFQGVQFNYPTRPDITVLQGLDISVKQGETLALVGSSGCGKSTTVSLLERFYDPFGGEVLVDGHSVRDLNIQWVRAQMGIVSQEPILFDCSIGENIAYGDNSREVTQAEIETAAKEANIHSFIDTLTDKYNTRVGDKGTQMSGGQKQRIAIARALVRKPKILLLDEATSALDTESEKVVQEALDK--ARTGRTCIVIAHRLSTIQNAD 1237
BLAST of SMED30003432 vs. Ensembl Xenopus
Match: mia2 (MIA SH3 domain ER export factor 2 [Source:Xenbase;Acc:XB-GENE-993630]) HSP 1 Score: 469.159 bits (1206), Expect = 4.276e-151 Identity = 240/560 (42.86%), Postives = 354/560 (63.21%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDL-------------TMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V + +FR+++ D ++++ I+SI GAA PL +++F D+ + V+ + + E+M ++ L + ++Q+ +L+A +Q +R+RSN+F+A+LRQEI WFD G+L T+LTDDV I GI DK+A +Q +++FV I+ F GWKL+ + P+M + ++ + ++ K++KAY+ AG +AEE+LSSIRTV AF Q+KE+KRY NL+EA+ +G+K++I + G I+ +L ++ G I G Y G+V+ +F ++IG+ A+G P +E F A+ AAY +F +ID P+I S K G+ P+ GDIEFKNV F YP+R + +L+ N +P GKTVA +G SG GKST + L+QRFYDP G I+ G D++ +++ + R IGVV QEP LF +I +NI+ G+ D EEI ++T+++NAY FIMK KF T +G+RG SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK A RT ++VAHRL T+RNAD Sbjct: 48 VGVFTMFRYSSTSDRILMLFGTIASISHGAALPLMMIVFGDMTDSFVNVGQVGSGNFSLEALINASRNLQEQMTTYAYYYSGLGFGVLLFAYVQISFWTLSAGKQIKRIRSNFFHAVLRQEIGWFDVNDAGELNTRLTDDVSKINEGIGDKIAMLLQSLTTFVTGFIIGFVKGWKLTLVILAISPVMGFSAAIWAKVLSAFTNKELKAYAKAGAVAEEVLSSIRTVFAFGGQDKEIKRYEKNLEEAKRIGIKKAITANVSIGFAFLMIYAAYALAFWYGTTLIINGGYTIGSVLTVFFAVIIGAFAVGQTSPNVEAFANARGAAYTIFNIIDNQPKIDSFSKEGLKPDKIKGDIEFKNVKFTYPSRTDIQVLKGLNLNIPSGKTVALVGSSGCGKSTTVQLIQRFYDPEEGVITLDGQDIRSLNIRYLREIIGVVSQEPILFDTTIADNIRYGREDVTMEEIERATKEANAYNFIMKLPDKFETLVGERGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESESVVQAALDK--AREGRTTIVVAHRLSTIRNAD 605 HSP 2 Score: 337.806 bits (865), Expect = 4.417e-102 Identity = 188/527 (35.67%), Postives = 293/527 (55.60%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAIL----SSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GA P +IF ++ + P + MR +++L +FI+ F+Q T ++RLR F ++LRQEI WFD K TG L T+L D ++ +LA Q I++ +I++F GW+L+ + +PI+A + + + ++ K K AG I+ + + +IRTVV+ + + K Y NL+ +K++ GL + ++ + + G + E P V +F IV G++ALG ++ A +A +F +++RVP I S+ K G P++ G+++F+ V F YPTRP + +LQ + ++ G+T+A +G SG GKST + LL+RFYDP GE+ G ++D+++ W R+ +G+V QEP LF SI ENI G + EI + +++N + FI K+NT +GD+G SGGQKQRIAIA ALVR P++LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 730 GATQPAFAIIFSKIIGVFAGP-------ASEMRAKSTMYSLLFLALGGISFITFFLQGFTFGKAGEILTKRLRLWSFKSMLRQEIGWFDDTKNSTGALTTRLATDASQVQGATGSRLALLAQNIANLGTAVIISFIYGWRLTLLILAIVPIIAASALVQLKMFAGHAKKDKKELEKAGKISTDAVLNIRTVVSLTRERKFEAMYEKNLEGPYRNSIKKAHLHGLTYALSQAIMYFAYAGCFRFGAYLVAELLMTPDDVFLVFSAIVFGAMALGQTSSFAPDYTKAMISAAHIFSLLERVPLIDSYSKEGEKPQNCGGNVQFQGVQFNYPTRPDITVLQGLDISVKQGETLALVGSSGCGKSTTVSLLERFYDPFGGEVLVDGHSVRDLNIQWVRAQMGIVSQEPILFDCSIGENIAYGDNSREVTQAEIETAAKEANIHSFIDTLTDKYNTRVGDKGTQMSGGQKQRIAIARALVRKPKILLLDEATSALDTESEKVVQEALDK--ARTGRTCIVIAHRLSTIQNAD 1247
BLAST of SMED30003432 vs. Ensembl Xenopus
Match: mia2 (MIA SH3 domain ER export factor 2 [Source:Xenbase;Acc:XB-GENE-993630]) HSP 1 Score: 468.003 bits (1203), Expect = 6.877e-151 Identity = 239/557 (42.91%), Postives = 353/557 (63.38%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPS----------VIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V + +FR+++ D ++++ I+SI GAA PL +++F D+ + V+ + + R + ++ L + ++Q+ +L+A +Q +R+RSN+F+A+LRQEI WFD G+L T+LTDDV I GI DK+A +Q +++FV I+ F GWKL+ + P+M + ++ + ++ K++KAY+ AG +AEE+LSSIRTV AF Q+KE+KRY NL+EA+ +G+K++I + G I+ +L ++ G I G Y G+V+ +F ++IG+ A+G P +E F A+ AAY +F +ID P+I S K G+ P+ GDIEFKNV F YP+R + +L+ N +P GKTVA +G SG GKST + L+QRFYDP G I+ G D++ +++ + R IGVV QEP LF +I +NI+ G+ D EEI ++T+++NAY FIMK KF T +G+RG SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK A RT ++VAHRL T+RNAD Sbjct: 48 VGVFTMFRYSSTSDRILMLFGTIASISHGAALPLMMIVFGDMTDSFVNVGQVAFHSTAHARANDTGRRKRCRYAYYYSGLGFGVLLFAYVQISFWTLSAGKQIKRIRSNFFHAVLRQEIGWFDVNDAGELNTRLTDDVSKINEGIGDKIAMLLQSLTTFVTGFIIGFVKGWKLTLVILAISPVMGFSAAIWAKVLSAFTNKELKAYAKAGAVAEEVLSSIRTVFAFGGQDKEIKRYEKNLEEAKRIGIKKAITANVSIGFAFLMIYAAYALAFWYGTTLIINGGYTIGSVLTVFFAVIIGAFAVGQTSPNVEAFANARGAAYTIFNIIDNQPKIDSFSKEGLKPDKIKGDIEFKNVKFTYPSRTDIQVLKGLNLNIPSGKTVALVGSSGCGKSTTVQLIQRFYDPEEGVITLDGQDIRSLNIRYLREIIGVVSQEPILFDTTIADNIRYGREDVTMEEIERATKEANAYNFIMKLPDKFETLVGERGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESESVVQAALDK--AREGRTTIVVAHRLSTIRNAD 602 HSP 2 Score: 317.39 bits (812), Expect = 7.755e-95 Identity = 182/526 (34.60%), Postives = 282/526 (53.61%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAIL----SSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GA P +IF ++ + P + MR +++L +FI+ F+Q T ++RLR F ++LRQEI WFD K TG L T+L D ++ +LA Q I++ +I++F GW+L+ + +PI+A + + + ++ K K AG I+ + + +IRTVV+ + + K Y NL+ +K++ GL + ++ + + G + E P V +F IV G++ALG ++ A +A +F +++R+ G I F+ V F YPTRP + +LQ + ++ G+T+A +G SG GKST + LL+RFYDP GE+ G ++D+++ W R+ +G+V QEP LF SI ENI G + EI + +++N + FI K+NT +GD+G SGGQKQRIAIA ALVR P++LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 719 GATQPAFAIIFSKIIGVFAGP-------ASEMRAKSTMYSLLFLALGGISFITFFLQGFTFGKAGEILTKRLRLWSFKSMLRQEIGWFDDTKNSTGALTTRLATDASQVQGATGSRLALLAQNIANLGTAVIISFIYGWRLTLLILAIVPIIAASALVQLKMFAGHAKKDKKELEKAGKISTDAVLNIRTVVSLTRERKFEAMYEKNLEGPYRNSIKKAHLHGLTYALSQAIMYFAYAGCFRFGAYLVAELLMTPDDVFLVFSAIVFGAMALGQTSSFAPDYTKAMISAAHIFSLLERLG---------------GYITFQGVQFNYPTRPDITVLQGLDISVKQGETLALVGSSGCGKSTTVSLLERFYDPFGGEVLVDGHSVRDLNIQWVRAQMGIVSQEPILFDCSIGENIAYGDNSREVTQAEIETAAKEANIHSFIDTLTDKYNTRVGDKGTQMSGGQKQRIAIARALVRKPKILLLDEATSALDTESEKVVQEALDK--ARTGRTCIVIAHRLSTIQNAD 1220
BLAST of SMED30003432 vs. Ensembl Xenopus
Match: mia2 (MIA SH3 domain ER export factor 2 [Source:Xenbase;Acc:XB-GENE-993630]) HSP 1 Score: 467.233 bits (1201), Expect = 1.426e-150 Identity = 242/553 (43.76%), Postives = 355/553 (64.20%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDV------VNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V + +FR+++ D ++++ I+SI GAA PL +++F D+ V +VSP + T ++ ++ L + ++Q+ +L+A +Q +R+RSN+F+A+LRQEI WFD G+L T+LTDDV I GI DK+A +Q +++FV I+ F GWKL+ + P+M + ++ + ++ K++KAY+ AG +AEE+LSSIRTV AF Q+KE+KRY NL+EA+ +G+K++I + G I+ +L ++ G I G Y G+V+ +F ++IG+ A+G P +E F A+ AAY +F +ID P+I S K G+ P+ GDIEFKNV F YP+R + +L+ N +P GKTVA +G SG GKST + L+QRFYDP G I+ G D++ +++ + R IGVV QEP LF +I +NI+ G+ D EEI ++T+++NAY FIMK KF T +G+RG SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK A RT ++VAHRL T+RNAD Sbjct: 48 VGVFTMFRYSSTSDRILMLFGTIASISHGAALPLMMIVFGDMTDSFVNVGQVVSP-NFTCLDDQKY---AYYYSGLGFGVLLFAYVQISFWTLSAGKQIKRIRSNFFHAVLRQEIGWFDVNDAGELNTRLTDDVSKINEGIGDKIAMLLQSLTTFVTGFIIGFVKGWKLTLVILAISPVMGFSAAIWAKVLSAFTNKELKAYAKAGAVAEEVLSSIRTVFAFGGQDKEIKRYEKNLEEAKRIGIKKAITANVSIGFAFLMIYAAYALAFWYGTTLIINGGYTIGSVLTVFFAVIIGAFAVGQTSPNVEAFANARGAAYTIFNIIDNQPKIDSFSKEGLKPDKIKGDIEFKNVKFTYPSRTDIQVLKGLNLNIPSGKTVALVGSSGCGKSTTVQLIQRFYDPEEGVITLDGQDIRSLNIRYLREIIGVVSQEPILFDTTIADNIRYGREDVTMEEIERATKEANAYNFIMKLPDKFETLVGERGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESESVVQAALDK--AREGRTTIVVAHRLSTIRNAD 594 HSP 2 Score: 337.806 bits (865), Expect = 3.142e-102 Identity = 188/527 (35.67%), Postives = 293/527 (55.60%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAIL----SSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GA P +IF ++ + P + MR +++L +FI+ F+Q T ++RLR F ++LRQEI WFD K TG L T+L D ++ +LA Q I++ +I++F GW+L+ + +PI+A + + + ++ K K AG I+ + + +IRTVV+ + + K Y NL+ +K++ GL + ++ + + G + E P V +F IV G++ALG ++ A +A +F +++RVP I S+ K G P++ G+++F+ V F YPTRP + +LQ + ++ G+T+A +G SG GKST + LL+RFYDP GE+ G ++D+++ W R+ +G+V QEP LF SI ENI G + EI + +++N + FI K+NT +GD+G SGGQKQRIAIA ALVR P++LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 710 GATQPAFAIIFSKIIGVFAGP-------ASEMRAKSTMYSLLFLALGGISFITFFLQGFTFGKAGEILTKRLRLWSFKSMLRQEIGWFDDTKNSTGALTTRLATDASQVQGATGSRLALLAQNIANLGTAVIISFIYGWRLTLLILAIVPIIAASALVQLKMFAGHAKKDKKELEKAGKISTDAVLNIRTVVSLTRERKFEAMYEKNLEGPYRNSIKKAHLHGLTYALSQAIMYFAYAGCFRFGAYLVAELLMTPDDVFLVFSAIVFGAMALGQTSSFAPDYTKAMISAAHIFSLLERVPLIDSYSKEGEKPQNCGGNVQFQGVQFNYPTRPDITVLQGLDISVKQGETLALVGSSGCGKSTTVSLLERFYDPFGGEVLVDGHSVRDLNIQWVRAQMGIVSQEPILFDCSIGENIAYGDNSREVTQAEIETAAKEANIHSFIDTLTDKYNTRVGDKGTQMSGGQKQRIAIARALVRKPKILLLDEATSALDTESEKVVQEALDK--ARTGRTCIVIAHRLSTIQNAD 1227
BLAST of SMED30003432 vs. Ensembl Mouse
Match: Abcb1a (ATP-binding cassette, sub-family B (MDR/TAP), member 1A [Source:MGI Symbol;Acc:MGI:97570]) HSP 1 Score: 450.284 bits (1157), Expect = 4.764e-144 Identity = 234/562 (41.64%), Postives = 348/562 (61.92%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVS---------------PRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 VS +FR+A +D L ++V +++I G A PL +LIF D+ + S R + E M + + + I +IQ+ L A RQ ++R +F+A++ QEI WFD G+L T+LTDDV I GI DK+ F Q +++F G I+ FT GWKL+ + P++ + + + ++ K++ AY+ AG +AEE+L++IRTV+AF Q+KE++RY++NL+EA+ LG+K++I + G I+ +L ++ G + Y G V+ +F +++IG+ ++G A P +E F A+ AAY +F++ID P I S K G P++ G++EFKN+ F YP+R V IL+ N + G+TVA +G SG GKST + L+QR YDPL G +S G D++ I++ + R IGVV QEP LF+ +I ENI+ G+ D +EI K+ +++NAY+FIMK +F+T +G+RGA SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK A RT +++AHRL TVRNAD Sbjct: 33 VSVLTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLIFGDMTDSFASVGNVSKNSTNMSEADKRAMFAKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKEYSIGQVLTVFFSVLIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDSFSKSGHKPDNIQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDK--AREGRTTIVIAHRLSTVRNAD 592 HSP 2 Score: 328.946 bits (842), Expect = 5.104e-99 Identity = 178/493 (36.11%), Postives = 282/493 (57.20%), Query Frame = -1 Query: 1 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNL--------KEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1440 F IL +FI+ F+Q T ++RLR F ++LRQ++ WFD K TG L T+L +D ++ +LA Q I++ II++ GW+L+ + +PI+A + + + ++K K +G IA E + + RTVV+ + ++K Y+ +L K+A G+ S Q + ++ + + G + + V+ +F IV G++A+G ++ A +A + ++I++ P+I S+ G+ P G+++F V F YPTRP +P+LQ + + G+T+A +G SG GKST++ LL+RFYDP+AG + G ++K +++ W R+ +G+V QEP LF SI ENI G + EEIV++ +++N ++FI K+NT +GD+G SGGQKQRIAIA ALVR P +LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 755 FLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAM--------MYFSYAACFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIEKTPEIDSYSTQGLKPNMLEGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK--AREGRTCIVIAHRLSTIQNAD 1237
BLAST of SMED30003432 vs. Ensembl Mouse
Match: Abcb1b (ATP-binding cassette, sub-family B (MDR/TAP), member 1B [Source:MGI Symbol;Acc:MGI:97568]) HSP 1 Score: 438.343 bits (1126), Expect = 1.228e-139 Identity = 212/493 (43.00%), Postives = 319/493 (64.71%), Query Frame = -1 Query: 1 TFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1476 + E M + + + I +IQ+ L A RQ ++R +F+A++ QEI WFD G+L T+LTDDV I GI DK+ F Q I++F+ I+ F +GWKL+ + P++ + +L + ++ K+++AY+ AG +AEE+L++IRTV+AF Q+KE++RY+ NL+EA+ +G+K++I + G+ ++ +L ++ G + Y G V+ +F +I++G+ ++G+ P +E F A+ AA+ +F++ID P I S G P+S G++EFKNV F YP+R V IL+ N + G+TVA +G SG GKST + L+QR YDPL G +S G D++ I++ + R IGVV QEP LF+ +I ENI+ G+ D +EI K+ +++NAY+FIMK +F+T +G+RGA SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK A RT +++AHRL TVRNAD Sbjct: 105 SLEEEMAIYAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINDGIGDKIGMFFQSITTFLAGFIIGFISGWKLTLVILAVSPLIGLSSALWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQQKELERYNKNLEEAKNVGIKKAITASISIGIAYLLVYASYALAFWYGTSLVLSNEYSIGEVLTVFFSILLGTFSIGHLAPNIEAFANARGAAFEIFKIIDNEPSIDSFSTKGYKPDSIMGNLEFKNVHFNYPSRSEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLEGVVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDK--AREGRTTIVIAHRLSTVRNAD 595 HSP 2 Score: 334.339 bits (856), Expect = 6.230e-101 Identity = 183/531 (34.46%), Postives = 299/531 (56.31%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNL--------KEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G P+ ++F +V + S D T + + F ++ +F++ F Q T ++R+R F ++LRQ+I WFD K TG L T+L D S++ + +LA Q +++ +IL+ GW+L+ + + IP++ + + + ++K K I+G IA E + + RT+V+ + ++K Y+ +L K+A G+ S Q + ++ + + G + + V+ +F +V G++A GN ++ AK +A + ++I++ P+I S+ G+ P G+++F V F YPTRP +P+LQ + + G+T+A +G SG GKST++ LL+RFYDP+AG + G ++K +++ W R+H+G+V QEP LF SI ENI G +EEIV++ +++N ++FI K+NT +GD+G SGGQKQRIAIA ALVR P +LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 720 GCIQPVFAIVFSRIVGVF-SRDDDHETKRQNCNLFSLFFLVMGLISFVTYFFQGFTFGKAGEILTKRVRYMVFKSMLRQDISWFDDHKNSTGSLTTRLASDASSVKGAMGARLAVVTQNVANLGTGVILSLVYGWQLTLLLVVIIPLIVLGGIIEMKLLSGQALKDKKQLEISGKIATEAIENFRTIVSLTREQKFETMYAQSLQVPYRNAMKKAHVFGITFSFTQAM--------MYFSYAACFRFGAYLVAQQLMTFENVMLVFSAVVFGAMAAGNTSSFAPDYAKAKVSASHIIRIIEKTPEIDSYSTEGLKPTLLEGNVKFNGVQFNYPTRPNIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRAVSHEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK--AREGRTCIVIAHRLSTIQNAD 1239
BLAST of SMED30003432 vs. Ensembl Mouse
Match: Abcb4 (ATP-binding cassette, sub-family B (MDR/TAP), member 4 [Source:MGI Symbol;Acc:MGI:97569]) HSP 1 Score: 417.927 bits (1073), Expect = 1.822e-135 Identity = 218/533 (40.90%), Postives = 330/533 (61.91%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVS-------PRDLTMT-------FSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G+ PL +++F ++ + V P + +++ E M ++ L ++ +IQ+ +L A RQ +++R +F+A+LRQE+ WFD + T +L T+LTDDV I GI DK+ F Q I++F I+ F GWKL+ + PI+ + ++ + +S K++ AY+ AG +AEE L +IRTV+AF Q KE++RY +L+ A+ +G+K++I + G+ I+ +L ++ G + Y G + +F +I+IG+ ++G A P ++ F A+ AAY +F +ID P+I S + G P++ G++EF +V F YP+R + IL+ N + G+TVA +G SG GKST + LLQR YDP G+IS G D+++ ++ R IGVV QEP LFS +I ENI+ G+ + +EI K+ +++NAY+FIMK QKF+T +GDRGA SGGQKQRIAIA ALVRNP++LLLDEATSALD SE VQ LDK A RT +++AHRL T+RNAD Sbjct: 65 GSGLPLMMIVFGEMTDKFVDNTGNFSLPVNFSLSMLNPGRILEEEMTRYAYYYSGLGGGVLVAAYIQVSFWTLAAGRQIKKIRQKFFHAILRQEMGWFDIKGTTELNTRLTDDVSKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLVIMAISPILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKKIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSERGHKPDNIKGNLEFSDVHFSYPSRANIKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGKISIDGQDIRNFNVRCLREIIGVVSQEPVLFSTTIAENIRYGRGNVTMDEIEKAVKEANAYDFIMKLPQKFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDK--AREGRTTIVIAHRLSTIRNAD 595 HSP 2 Score: 64.3142 bits (155), Expect = 3.623e-10 Identity = 36/111 (32.43%), Postives = 56/111 (50.45%), Query Frame = -1 Query: 1114 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMA 1440 F L +F + F+Q T + RLRS F A+LRQ++ WFD K TG L T+L D ++ +LA Q ++ II++F GW+L+ + +P +A Sbjct: 755 FLGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNTANLGTGIIISFIYGWQLTLLLLSVVPFIA 865
BLAST of SMED30003432 vs. Ensembl Mouse
Match: Abcb5 (ATP-binding cassette, sub-family B (MDR/TAP), member 5 [Source:MGI Symbol;Acc:MGI:1924956]) HSP 1 Score: 418.313 bits (1074), Expect = 3.510e-132 Identity = 225/559 (40.25%), Postives = 346/559 (61.90%), Query Frame = -1 Query: 1 QLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSP----------RDLTMTFSERMRPSVIKFAI----LSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMG--LLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISH-KKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1626 ++FRFA +D++++ + I++S+ GA PL L+ ++ + L++ ++ + T E++ +I + + + I G++Q+ +TAARQ+ R+R +F+++L Q+I WFD +L T++T D+ + GI DK+ Q IS F ++++ WKLS + + P++ + +L I + K++ AYS AG +AEE LSSI+TV AF AQEKE++RY+ +LK+A+ G+KR+ L G + F + L ++ G L+F E Y GT++ +F +++ S +G+ P LE F A+ AA+ +FQVID+ P I + G +PE G+IEFKNV F YP+RP +L+ N + G+TVA +GPSGSGKST + LLQR YDP G I+ D++ ++ YR IGVV+QEP LF +I NI+ G+ +E+ ++ +++NAY+FIM +KFNT +G++GA SGGQKQRIAIA ALVRNP++L+LDEATSALD SE LVQ L+K A RT ++VAHRL T+R AD Sbjct: 36 EIFRFADNLDIVLMTLGILASMINGATVPLMSLVLGEISDHLINGCLVQTNRTKYQNCSQT-QEKLNEDIIVLTLYYIGIGAAALIFGYVQISFWVITAARQTTRIRKQFFHSILAQDISWFDGSDICELNTRMTGDINKLCDGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLVVLSTSPLIMASSALCSRMIISLTSKELDAYSKAGAVAEEALSSIQTVTAFGAQEKEIQRYTQHLKDAKDAGIKRATASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPGYTIGTILAVFFSVIHSSYCIGSVAPHLETFTVARGAAFNIFQVIDKKPNIDNFSTAGFVPECIEGNIEFKNVSFSYPSRPSAKVLKGLNLKIKAGETVALVGPSGSGKSTTVQLLQRLYDPEDGCITVDENDIRAQNVRHYREQIGVVRQEPVLFGTTIGNNIKFGREGVGEKEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQTALEK--ASKGRTTIVVAHRLSTIRGAD 591 HSP 2 Score: 318.546 bits (815), Expect = 2.221e-95 Identity = 183/523 (34.99%), Postives = 286/523 (54.68%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQ--TGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAIN--EEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G+ P+ +IF +V + T+ + ++ +L ++ +Q + + RLR + F A+L Q++ W+D ++ TG L T L DV I+ + +L Q +S+ I+++F GW+++ + P++A T + + ++ + +A AG IA E + +IRTVV+ + + + Y L+ +KR+ G V + + + G I G P + +F I G++A+G + + AKA A LF ++ P I S + G P++ G++EF+ V F YP RP VP+LQN + ++ GKTVAF+G SG GKST + LLQRFYDP+ G++ G D+K++++ W RS +V QEP LF+ SI ENI G + EEI + +N + FI +K+NT +G RG SGGQKQR+AIA AL+R P++LLLDEATSALDN SEK+VQ+ LDK A +T ++VAHRL T++NAD Sbjct: 704 GSVHPVFSIIFGKLVTMFEDKNKATLKQDAELYSMML--VVLGIVALVTYLMQGLFYGRAEENLAMRLRHSAFKAMLYQDMAWYDDKENNTGALTTTLAVDVAQIQGAATSRLGIVTQDVSNMSLSILISFIYGWEMTLLILSFAPVLAVTGMIQTAAMAGFANRDKQALKRAGKIATEAVENIRTVVSLTRERAFEQMYEETLQTQHRNALKRAHITGCCYAVSHAFVHFAHAAGFRFGAYLIQAGRMMPEGMFIVFTAIAYGAMAIGETLVWAPEYSKAKAGASHLFALLKNKPTINSCSQSGEKPDTCEGNLEFREVSFVYPCRPEVPVLQNMSLSIEKGKTVAFVGSSGCGKSTCVQLLQRFYDPMKGQVLLDGVDVKELNVQWLRSQTAIVSQEPVLFNCSIAENIAYGDNSRMVPLEEIKEVADAANIHSFIEGLPRKYNTLVGLRGVQLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKVVQQALDK--ARRGKTCLVVAHRLSTIQNAD 1222
BLAST of SMED30003432 vs. Ensembl Mouse
Match: Abcb4 (ATP-binding cassette, sub-family B (MDR/TAP), member 4 [Source:MGI Symbol;Acc:MGI:97569]) HSP 1 Score: 417.157 bits (1071), Expect = 1.144e-131 Identity = 218/533 (40.90%), Postives = 330/533 (61.91%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVS-------PRDLTMT-------FSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G+ PL +++F ++ + V P + +++ E M ++ L ++ +IQ+ +L A RQ +++R +F+A+LRQE+ WFD + T +L T+LTDDV I GI DK+ F Q I++F I+ F GWKL+ + PI+ + ++ + +S K++ AY+ AG +AEE L +IRTV+AF Q KE++RY +L+ A+ +G+K++I + G+ I+ +L ++ G + Y G + +F +I+IG+ ++G A P ++ F A+ AAY +F +ID P+I S + G P++ G++EF +V F YP+R + IL+ N + G+TVA +G SG GKST + LLQR YDP G+IS G D+++ ++ R IGVV QEP LFS +I ENI+ G+ + +EI K+ +++NAY+FIMK QKF+T +GDRGA SGGQKQRIAIA ALVRNP++LLLDEATSALD SE VQ LDK A RT +++AHRL T+RNAD Sbjct: 65 GSGLPLMMIVFGEMTDKFVDNTGNFSLPVNFSLSMLNPGRILEEEMTRYAYYYSGLGGGVLVAAYIQVSFWTLAAGRQIKKIRQKFFHAILRQEMGWFDIKGTTELNTRLTDDVSKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLVIMAISPILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKKIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSERGHKPDNIKGNLEFSDVHFSYPSRANIKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGKISIDGQDIRNFNVRCLREIIGVVSQEPVLFSTTIAENIRYGRGNVTMDEIEKAVKEANAYDFIMKLPQKFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDK--AREGRTTIVIAHRLSTIRNAD 595 HSP 2 Score: 331.257 bits (848), Expect = 8.495e-100 Identity = 188/493 (38.13%), Postives = 280/493 (56.80%), Query Frame = -1 Query: 1 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQ--------EKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1440 F L +F + F+Q T + RLRS F A+LRQ++ WFD K TG L T+L D ++ +LA Q ++ II++F GW+L+ + +P +A + + + + + K AG IA E + +IRTVV+ + + EK Y +++++A G+ SI Q F F+ + G I G VI +F IV+G++ALG+A ++ AK +A LF + +R P I S+ G+ P+ F G + F V F YPTR VP+LQ + + G+T+A +G SG GKST++ LL+RFYDP+AG + G + K +++ W R+ +G+V QEP LF SI ENI G + ++EIV++ +++N + FI QK+NT +GD+G SGGQKQRIAIA AL+R P++LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 755 FLGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNTANLGTGIIISFIYGWQLTLLLLSVVPFIAVAGIVEMKMLAGNAKRDKKEMEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLHGPYRNSVRKAHIYGITFSISQA-------FMYFSYAG-CFRFGSYLIVNGHMRFKDVILVFSAIVLGAVALGHASSFAPDYAKAKLSAAYLFSLFERQPLIDSYSGEGLWPDKFEGSVTFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVPHDEIVRAAKEANIHPFIETLPQKYNTRVGDKGTQLSGGQKQRIAIARALIRQPRVLLLDEATSALDTESEKVVQEALDK--AREGRTCIVIAHRLSTIQNAD 1237
BLAST of SMED30003432 vs. UniProt/SwissProt
Match: sp|P21447|MDR1A_MOUSE (ATP-dependent translocase ABCB1 OS=Mus musculus OX=10090 GN=Abcb1a PE=1 SV=3) HSP 1 Score: 450.284 bits (1157), Expect = 3.332e-143 Identity = 234/562 (41.64%), Postives = 348/562 (61.92%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVS---------------PRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 VS +FR+A +D L ++V +++I G A PL +LIF D+ + S R + E M + + + I +IQ+ L A RQ ++R +F+A++ QEI WFD G+L T+LTDDV I GI DK+ F Q +++F G I+ FT GWKL+ + P++ + + + ++ K++ AY+ AG +AEE+L++IRTV+AF Q+KE++RY++NL+EA+ LG+K++I + G I+ +L ++ G + Y G V+ +F +++IG+ ++G A P +E F A+ AAY +F++ID P I S K G P++ G++EFKN+ F YP+R V IL+ N + G+TVA +G SG GKST + L+QR YDPL G +S G D++ I++ + R IGVV QEP LF+ +I ENI+ G+ D +EI K+ +++NAY+FIMK +F+T +G+RGA SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK A RT +++AHRL TVRNAD Sbjct: 33 VSVLTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLIFGDMTDSFASVGNVSKNSTNMSEADKRAMFAKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKEYSIGQVLTVFFSVLIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDSFSKSGHKPDNIQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDK--AREGRTTIVIAHRLSTVRNAD 592 HSP 2 Score: 328.946 bits (842), Expect = 3.571e-98 Identity = 178/493 (36.11%), Postives = 282/493 (57.20%), Query Frame = -1 Query: 1 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNL--------KEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1440 F IL +FI+ F+Q T ++RLR F ++LRQ++ WFD K TG L T+L +D ++ +LA Q I++ II++ GW+L+ + +PI+A + + + ++K K +G IA E + + RTVV+ + ++K Y+ +L K+A G+ S Q + ++ + + G + + V+ +F IV G++A+G ++ A +A + ++I++ P+I S+ G+ P G+++F V F YPTRP +P+LQ + + G+T+A +G SG GKST++ LL+RFYDP+AG + G ++K +++ W R+ +G+V QEP LF SI ENI G + EEIV++ +++N ++FI K+NT +GD+G SGGQKQRIAIA ALVR P +LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 755 FLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAM--------MYFSYAACFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIEKTPEIDSYSTQGLKPNMLEGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK--AREGRTCIVIAHRLSTIQNAD 1237
BLAST of SMED30003432 vs. UniProt/SwissProt
Match: sp|P21448|MDR1_CRIGR (ATP-dependent translocase ABCB1 OS=Cricetulus griseus OX=10029 GN=ABCB1 PE=1 SV=2) HSP 1 Score: 449.899 bits (1156), Expect = 3.439e-143 Identity = 233/563 (41.39%), Postives = 349/563 (61.99%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLL----------------VSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 VS + +FR+A +D L ++V +++I G A PL +L+F D+ + V+ D+ E M + + + I +IQ+ L A RQ ++R +F+A++ QEI WFD G+L T+LTDDV I GI DK+ F Q +++F G I+ FT GWKL+ + P++ + + + ++ K+++AY+ AG +AEE+L++IRTV+AF Q+KE++RY++NL+EA+ LG+K++I + G I+ +L ++ G + Y G V+ +F ++IG+ ++G A P +E F A+ AAY +F +ID P I S K+G P++ G++EFKN+ F YP+R V IL+ N + G+TVA +G SG GKST + LLQR YDP G +S G D++ I++ + R IGVV QEP LF+ +I ENI+ G+ + +EI K+ +++NAY+FIMK KF+T +G+RGA SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK A RT +++AHRL TVRNAD Sbjct: 33 VSVFTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLVFGDMTDSFASVGNIPTNATNNATQVNASDIFGKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKEYSIGQVLTVFFAVLIGAFSIGQASPNIEAFANARGAAYEIFNIIDNKPSIDSFSKNGYKPDNIKGNLEFKNIHFSYPSRKDVQILKGLNLKVQSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGVVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDK--AREGRTTIVIAHRLSTVRNAD 593 HSP 2 Score: 331.643 bits (849), Expect = 3.553e-99 Identity = 188/531 (35.40%), Postives = 295/531 (55.56%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNL--------KEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GA P +IF VV + D + S++ F IL +FI+ F+Q T ++RLR F ++LRQ++ WFD K TG L T+L +D ++ +LA Q I++ II++ GW+L+ + +PI+A + + + ++K K +G IA E + + RTVV+ + ++K Y+ +L K+A G+ S Q + ++ + + G + V+ +F IV G++A+G ++ AK +A + +I++VP I S+ G+ P + G+++F V F YPTRP +P+LQ N + G+T+A +G SG GKST++ LL+RFYDP+AG + G ++ +++ W R+H+G+V QEP LF SI ENI G + +EI ++ +++N ++FI K+NT +GD+G SGGQKQRIAIA ALVR P +LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 719 GALQPAFSIIFSKVVGVFTRNTDDETKRHDSNLFSLL-FLILGVISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDNPKNTTGALTTRLANDAGQVKGATGARLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFENMYAQSLQIPYRNALKKAHVFGITFSFTQAM--------MYFSYAACFRFGAYLVARELMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKAKVSASHIIMIIEKVPSIDSYSTGGLKPNTLEGNVKFNEVVFNYPTRPDIPVLQGLNLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEVNQLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIERAAKEANIHQFIESLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK--AREGRTCIVIAHRLSTIQNAD 1238
BLAST of SMED30003432 vs. UniProt/SwissProt
Match: sp|P08183|MDR1_HUMAN (ATP-dependent translocase ABCB1 OS=Homo sapiens OX=9606 GN=ABCB1 PE=1 SV=3) HSP 1 Score: 449.899 bits (1156), Expect = 4.203e-143 Identity = 229/565 (40.53%), Postives = 354/565 (62.65%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDLT------------------MTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 VS + +FR++ +D L ++V +++I GA PL +L+F ++ ++ + +L M E M ++ + + ++ +IQ+ L A RQ ++R +F+A++RQEI WFD G+L T+LTDDV I GI DK+ F Q +++F I+ FT GWKL+ + P++ + ++ + ++ K++ AY+ AG +AEE+L++IRTV+AF Q+KE++RY+ NL+EA+ +G+K++I + G I+ +L ++ G + G Y G V+ +F +++IG+ ++G A P +E F A+ AAY +F++ID P I S+ K G P++ G++EF+NV F YP+R V IL+ N + G+TVA +G SG GKST + L+QR YDP G +S G D++ I++ + R IGVV QEP LF+ +I ENI+ G+ + +EI K+ +++NAY+FIMK KF+T +G+RGA SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK A RT +++AHRL TVRNAD Sbjct: 34 VSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNRSDINDTGFFMNLEEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSGEYSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK--ARKGRTTIVIAHRLSTVRNAD 596 HSP 2 Score: 332.028 bits (850), Expect = 3.315e-99 Identity = 181/497 (36.42%), Postives = 286/497 (57.55%), Query Frame = -1 Query: 1 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGT------------VIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1440 F L +FI+ F+Q T ++RLR F ++LRQ++ WFD K TG L T+L +D ++ I +LA Q I++ II++F GW+L+ + +PI+A + + + ++K K +G IA E + + RTVV+ + ++K Y+ +L+ ++++ + G T +++Y F Y G + G V+ +F +V G++A+G ++ AK +A + +I++ P I S+ G++P + G++ F V F YPTRP +P+LQ + + G+T+A +G SG GKST++ LL+RFYDPLAG++ G ++K +++ W R+H+G+V QEP LF SI ENI G + EEIV++ +++N + FI K++T +GD+G SGGQKQRIAIA ALVR P +LLLDEATSALD SEK+VQ+ LDK A RT +++AHRL T++NAD Sbjct: 759 FLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKA-------HIFGITFSFTQAMMY-----FSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISAAHIIMIIEKTPLIDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK--AREGRTCIVIAHRLSTIQNAD 1241
BLAST of SMED30003432 vs. UniProt/SwissProt
Match: sp|P43245|MDR1_RAT (ATP-dependent translocase ABCB1 OS=Rattus norvegicus OX=10116 GN=Abcb1 PE=2 SV=1) HSP 1 Score: 439.884 bits (1130), Expect = 2.574e-139 Identity = 231/566 (40.81%), Postives = 348/566 (61.48%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRD--------------LTMTFS-----ERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V + +FR+A +D L + + +++I G PL +L+F + + RD T T S E M + + + I +IQ+ L A RQ ++R +F+A++ QEI WFD G+L T+LTDDV I GI DKL F Q I++F I+ F +GWKL+ + P++ + ++ + ++ K+++AY+ AG +AEE+L++IRTV+AF Q+KE++RY+ NL+EA+ +G+K++I + G+ ++ +L ++ G + Y G V+ +F +I++G+ ++G+ P +E F A+ AAY +F++ID P I S G P+S G++EFKNV F YP+R V IL+ N + G+TVA +G SG GKST + LLQR YDP+ GE+S G D++ I++ + R IGVV QEP LF+ +I ENI+ G+ + +EI K+ +++NAY+FIMK KF+T +G+RGA SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK A RT +++AHRL TVRNAD Sbjct: 32 VGIFGMFRYADWLDKLCMALGTLAAIIHGTLLPLLMLVFGYMTDSFTPSRDPHSDRAITNQSEINSTHTVSDTSLEEDMAMYAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVNDAGELNTRLTDDVSKINDGIGDKLGMFFQSITTFSAGFIIGFISGWKLTLVILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRVGIKKAITANISIGIAYLLVYASYALAFWYGTSLVLSNEYSIGQVLTVFFSILLGTFSIGHLAPNIEAFANARGAAYEIFKIIDNEPSIDSFSTKGHKPDSIMGNLEFKNVYFNYPSRSEVKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPIEGEVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDK--AREGRTTIVIAHRLSTVRNAD 595 HSP 2 Score: 319.316 bits (817), Expect = 1.306e-94 Identity = 181/525 (34.48%), Postives = 296/525 (56.38%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTT--GWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G P+ ++F +V + S D T + F ++ +F++ F Q T ++RLR F ++LRQ+I WFD K TG L T+L D +++ + +LA Q +++ IIL+ GW+L+ + + IP++ + + + ++K K I+G IA E + + RTVV+ + ++K Y+ +L+ +K++ G+ I+ + + G + V+ +F +V G++A GN ++ AK +A + +I+++P+I S+ G+ P G+++F V F YPTRP +P+LQ +F + G+T+ +G SG GKST++ LL+RFY+P+AG + G ++K +++ R+ +G+V QEP LF SI ENI G + +EEIV++ +++N ++FI +K+NT +GD+G SGGQKQRIAIA ALVR P +LLLDEATSALD SEK+VQ+ LDK A RT V++AHRL T++NAD Sbjct: 720 GCIQPVFAIVFSKIVGVF-SRDDDHETKQRNCNLFSLLFLVMGMISFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTTGSLTTRLASDASNVKGAMGSRLAVVTQNVANLGTGIILSLVLVYGWQLTLLLVVIIPLIVLGGIIEMKLLSGQALKDKKELEISGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNALKKAHVFGITFAFTQAMIYFSYAACFRFGAYLVARELMTFENVMLVFSAVVFGAMAAGNTSSFAPDYAKAKVSASHIIGIIEKIPEIDSYSTEGLKPNWLEGNVKFNGVKFNYPTRPNIPVLQGLSFEVKKGQTLRLVGSSGCGKSTVVQLLERFYNPMAGTVFLDGKEIKQLNVQCVRA-LGIVSQEPILFDCSIAENIAYGDNSRVVSHEEIVRAAREANIHQFIDSLPEKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK--AREGRTCVVIAHRLSTIQNAD 1240
BLAST of SMED30003432 vs. UniProt/SwissProt
Match: sp|Q2M3G0|ABCB5_HUMAN (ATP-binding cassette sub-family B member 5 OS=Homo sapiens OX=9606 GN=ABCB5 PE=1 SV=4) HSP 1 Score: 439.113 bits (1128), Expect = 3.522e-139 Identity = 234/562 (41.64%), Postives = 354/562 (62.99%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSP----------RDLTMT---FSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGS--YDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISH-KKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V ++FRFA G+D+ ++I+ I++S+ GA PL L+ ++ + L+S ++ T + +E M + + + I G+IQ+ +TAARQ++R+R +F+++L Q+I WFD G+L T++TDD++ I GI DK+A Q +S+F + + GWKL+ + + P++ + + + + K++ AYS AG +AEE+LSSIRTV+AF AQEKE++RY+ NLK+A+ G+KR+I + G + F + L ++ G I G Y GTV+ +F +++ S +G AVP E F A+ AA+ +FQVID+ P I + G PES G +EFKNV F YP+RP + IL+ N + G+TVA +G +GSGKST++ LLQR YDP G I D++ +++ YR HIGVV QEP LF +I NI+ G+ D +EE+ ++ +++NAY+FIM+ KFNT +G++GA SGGQKQRIAIA ALVRNP++L+LDEATSALD+ S+ VQ L+K A RT ++VAHRL T+R+AD Sbjct: 31 VGSIEIFRFADGLDITLMILGILASLVNGACLPLMPLVLGEMSDNLISGCLVQTNTTNYQNCTQSQEKLNEDMTLLTLYYVGIGVAALIFGYIQISLWIITAARQTKRIRKQFFHSVLAQDIGWFDSCDIGELNTRMTDDIDKISDGIGDKIALLFQNMSTFSIGLAVGLVKGWKLTLVTLSTSPLIMASAAACSRMVISLTSKELSAYSKAGAVAEEVLSSIRTVIAFRAQEKELQRYTQNLKDAKDFGIKRTIASKVSLGAVYFFMNGTYGLAFWYGTSLILNGEPGYTIGTVLAVFFSVIHSSYCIGAAVPHFETFAIARGAAFHIFQVIDKKPSIDNFSTAGYKPESIEGTVEFKNVSFNYPSRPSIKILKGLNLRIKSGETVALVGLNGSGKSTVVQLLQRLYDPDDGFIMVDENDIRALNVRHYRDHIGVVSQEPVLFGTTISNNIKYGRDDVTDEEMERAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEK--ASKGRTTIVVAHRLSTIRSAD 590 HSP 2 Score: 310.457 bits (794), Expect = 1.479e-91 Identity = 185/531 (34.84%), Postives = 289/531 (54.43%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQ--TGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNL--------KEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAIN--EEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G P+ +IF ++ + + T+ + + F IL F+S F+Q + + RLR F A+L Q+I WFD+++ TG L T L D+ I+ ++ Q ++ +I++F GW+++F+ P++A T + + ++ K + AG IA E L +IRT+V+ + ++ + Y L K+A+ +G C I F + G + G I G P + +F I G++A+G + + + AK+ A LF ++++ P I S + G P++ G++EF+ V F YP RP V IL+ + ++ GKTVAF+G SG GKST + LLQR YDP+ G++ F G D K++++ W RS I +V QEP LF+ SI ENI G + +EI ++ +N + FI +K+NT +G +GA SGGQKQR+AIA AL++ P++LLLDEATSALDN SEK+VQ LDK A RT ++V HRL ++NAD Sbjct: 703 GTVHPVFSIIFAKIITMFGNNDKTTLKHDAEIYSMI--FVILGVICFVSYFMQGLFYGRAGEILTMRLRHLAFKAMLYQDIAWFDEKENSTGGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIISFIYGWEMTFLILSIAPVLAVTGMIETAAMTGFANKDKQELKHAGKIATEALENIRTIVSLTREKAFEQMYEEMLQTQHRNTSKKAQIIGS----CYAFSHAFIYFA-YAAG---FRFGAYLIQAGRMTPEGMFIVFTAIAYGAMAIGETLVLAPEYSKAKSGAAHLFALLEKKPNIDSRSQEGKKPDTCEGNLEFREVSFFYPCRPDVFILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQEPVLFNCSIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK--ARTGRTCLVVTHRLSAIQNAD 1221
BLAST of SMED30003432 vs. TrEMBL
Match: A0A4S2MG49 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000267 PE=4 SV=1) HSP 1 Score: 521.546 bits (1342), Expect = 2.538e-168 Identity = 258/550 (46.91%), Postives = 373/550 (67.82%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVS----PRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V +++LF++A D ++ ++ ++ GA FPLN+ I+R ++ VS P D+ +V F IL + F FIQ + + ++++RQ RR+R YF A+LRQ++ WF+KQ +G LV KL+++V+ I++GI K FIQ IS F+ +I+AF GWKLS + +P++A F+L +K ++K++ AYS AGGIA E+LS+IRTVVAF +EKE RYS L A+ GVK+S+ G G+IG T+FT ++V++ G+ + Y GTV+ +F +++GSI LGNA+P L+ F+TA AAA ++ I+R+P I G PE F+G+I F++++F YPTRP +LQ F+ L G+TVA +GPSGSGKST++H+LQRFY+P+ G I GTD++++DL +RS G VQQEP LF G++ ENI++GK+DA EI ++ + +NA++FI+ + +NT +G+RG G SGGQKQRIAIA AL+R P+LLLLDEATSALD SE++VQ LDK A RTVVMVAHRL TVRNAD Sbjct: 18 VKFWRLFQYADAADKACIVCSVLCALGAGAGFPLNIFIYRGTIDNFVSTEFSPTDVY--------ANVKWFVILGAVIFCITFIQSMLLGISSSRQGRRIRLLYFEAILRQDVPWFEKQTSGGLVQKLSENVDIIQNGIGTKFGDFIQNISGFLAGLIIAFAVGWKLSLVAFAMLPLVAIAFALFGFLMKILTMKEVSAYSRAGGIANEVLSAIRTVVAFGGEEKEYNRYSAELTTAQKQGVKKSMAVGGVMGLIGLTLFTSAAVVFWYGVELMLTAEYTAGTVVAVFFNVILGSIYLGNALPGLQYFLTATAAARDVYDTIERIPSIDKNYAGTFPEDFHGNINFQDIEFVYPTRPDTTVLQEFSMNLREGQTVALVGPSGSGKSTVVHMLQRFYEPVEGRILVEGTDIRELDLKAFRSQQGFVQQEPVLFEGTVAENIRMGKLDADQAEIEEAARLANAHDFILSLPEGYNTVVGERGTGMSGGQKQRIAIARALIRKPRLLLLDEATSALDTNSERIVQAALDK--ASSGRTVVMVAHRLTTVRNAD 557 HSP 2 Score: 280.796 bits (717), Expect = 1.688e-78 Identity = 167/472 (35.38%), Postives = 263/472 (55.72%), Query Frame = -1 Query: 1 LTAARQSRRLRSNYFNALLRQEICWFDKQ--QTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSH----NLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLA----GEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1380 ++ R ++RLRS F A+L Q+I WFD+Q Q G L +L + +++ L ++ + I++AF W+L+ + P++ + L + ++ + +++ IA+E LS+ +TV AF+ ++ KR+ + NLK + S+ L ++ F SL Y+ + + S + ++F+ + + S +LG ++ A AA +F +DR+P I E F G +EFKNV F YP+RPG IL+ F+ + G++VA +G SG GKST++ L+QRFYDP+ + F G +L+ + +W R IG+V QEP LF SI+ENI G + EEI+++ + +N ++F+ Q ++T +G RG SGGQKQR+AIA AL+R P LLLLDEATSALDN SE++VQ+ LD + GK T ++VAHRL TV N D Sbjct: 734 VSGERLTQRLRSQLFKAILSQDIGWFDRQENQPGILTARLATEASKLKALSGSSLGFIVEAGVLSIISIVVAFIYSWQLALLVLGFAPVLVLSGMLQVKRMQGGDGTSVSLFAMK--IAQEALSAEKTVFAFNLEDYFYKRFGNALQSNLKSELKDNLVTSLVFALTQSIMMFCFAASMSLGAYL----LNQNSLTLVGLFRVFIVLNMSSQSLGRTASIVPELTAAAKAAKSIFSTMDRIPHILTDAGEKPIEQFTGQVEFKNVTFTYPSRPGTRILKRFSHCISAGESVALVGVSGCGKSTLLQLVQRFYDPIHTGPDSGVFFDGHNLRSLAPSWIRRQIGIVSQEPNLFDLSIRENIAYGDNSKEVSMEEIIEAARQANIHDFVSTLPQGYDTQVGARGGKLSGGQKQRVAIARALIRKPALLLLDEATSALDNESERIVQQALDGIV--GKCTSIVVAHRLTTVENVD 1197
BLAST of SMED30003432 vs. TrEMBL
Match: A0A4V6RH95 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000267 PE=4 SV=1) HSP 1 Score: 521.546 bits (1342), Expect = 3.713e-168 Identity = 258/550 (46.91%), Postives = 373/550 (67.82%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVS----PRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V +++LF++A D ++ ++ ++ GA FPLN+ I+R ++ VS P D+ +V F IL + F FIQ + + ++++RQ RR+R YF A+LRQ++ WF+KQ +G LV KL+++V+ I++GI K FIQ IS F+ +I+AF GWKLS + +P++A F+L +K ++K++ AYS AGGIA E+LS+IRTVVAF +EKE RYS L A+ GVK+S+ G G+IG T+FT ++V++ G+ + Y GTV+ +F +++GSI LGNA+P L+ F+TA AAA ++ I+R+P I G PE F+G+I F++++F YPTRP +LQ F+ L G+TVA +GPSGSGKST++H+LQRFY+P+ G I GTD++++DL +RS G VQQEP LF G++ ENI++GK+DA EI ++ + +NA++FI+ + +NT +G+RG G SGGQKQRIAIA AL+R P+LLLLDEATSALD SE++VQ LDK A RTVVMVAHRL TVRNAD Sbjct: 31 VKFWRLFQYADAADKACIVCSVLCALGAGAGFPLNIFIYRGTIDNFVSTEFSPTDVY--------ANVKWFVILGAVIFCITFIQSMLLGISSSRQGRRIRLLYFEAILRQDVPWFEKQTSGGLVQKLSENVDIIQNGIGTKFGDFIQNISGFLAGLIIAFAVGWKLSLVAFAMLPLVAIAFALFGFLMKILTMKEVSAYSRAGGIANEVLSAIRTVVAFGGEEKEYNRYSAELTTAQKQGVKKSMAVGGVMGLIGLTLFTSAAVVFWYGVELMLTAEYTAGTVVAVFFNVILGSIYLGNALPGLQYFLTATAAARDVYDTIERIPSIDKNYAGTFPEDFHGNINFQDIEFVYPTRPDTTVLQEFSMNLREGQTVALVGPSGSGKSTVVHMLQRFYEPVEGRILVEGTDIRELDLKAFRSQQGFVQQEPVLFEGTVAENIRMGKLDADQAEIEEAARLANAHDFILSLPEGYNTVVGERGTGMSGGQKQRIAIARALIRKPRLLLLDEATSALDTNSERIVQAALDK--ASSGRTVVMVAHRLTTVRNAD 570 HSP 2 Score: 280.796 bits (717), Expect = 1.566e-78 Identity = 167/472 (35.38%), Postives = 263/472 (55.72%), Query Frame = -1 Query: 1 LTAARQSRRLRSNYFNALLRQEICWFDKQ--QTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSH----NLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLA----GEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1380 ++ R ++RLRS F A+L Q+I WFD+Q Q G L +L + +++ L ++ + I++AF W+L+ + P++ + L + ++ + +++ IA+E LS+ +TV AF+ ++ KR+ + NLK + S+ L ++ F SL Y+ + + S + ++F+ + + S +LG ++ A AA +F +DR+P I E F G +EFKNV F YP+RPG IL+ F+ + G++VA +G SG GKST++ L+QRFYDP+ + F G +L+ + +W R IG+V QEP LF SI+ENI G + EEI+++ + +N ++F+ Q ++T +G RG SGGQKQR+AIA AL+R P LLLLDEATSALDN SE++VQ+ LD + GK T ++VAHRL TV N D Sbjct: 747 VSGERLTQRLRSQLFKAILSQDIGWFDRQENQPGILTARLATEASKLKALSGSSLGFIVEAGVLSIISIVVAFIYSWQLALLVLGFAPVLVLSGMLQVKRMQGGDGTSVSLFAMK--IAQEALSAEKTVFAFNLEDYFYKRFGNALQSNLKSELKDNLVTSLVFALTQSIMMFCFAASMSLGAYL----LNQNSLTLVGLFRVFIVLNMSSQSLGRTASIVPELTAAAKAAKSIFSTMDRIPHILTDAGEKPIEQFTGQVEFKNVTFTYPSRPGTRILKRFSHCISAGESVALVGVSGCGKSTLLQLVQRFYDPIHTGPDSGVFFDGHNLRSLAPSWIRRQIGIVSQEPNLFDLSIRENIAYGDNSKEVSMEEIIEAARQANIHDFVSTLPQGYDTQVGARGGKLSGGQKQRVAIARALIRKPALLLLDEATSALDNESERIVQQALDGIV--GKCTSIVVAHRLTTVENVD 1210
BLAST of SMED30003432 vs. TrEMBL
Match: A0A4E0RLC9 (Multidrug resistance protein 1 OS=Fasciola hepatica OX=6192 GN=D915_007290 PE=4 SV=1) HSP 1 Score: 513.072 bits (1320), Expect = 5.996e-165 Identity = 255/547 (46.62%), Postives = 372/547 (68.01%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIK-FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 VS+++LF A D + ++ I S+ GA FPLNVLIFR +++ + P +F + ++K FA+L +C + F+Q ++A RQSRR+R YF A+LRQ++ WFD Q +G L+ KLT ++++IE GI K FI +S F +I+AF GWKL+ + +P + T F +K +++K++ AYS A I+ E+LS+IRTV+AF ++KE +RYS L A+ +G+ +S G G IG T+F+ +L+++ G+ I +Y GTV+ +F+ +VIGSI LGNA+P ++ F+ A A+A ++ +IDRVP I + G F G+I FK+VDF YPTRP + +L+ FN L G+TVA +GPSGSGKSTI+H+LQRFYDP+ GEI G +++D+DL +R+ +G VQQEP LF G++++NI+LGK+DA NEEI+++ + +NA++FI+ + + T L +RGAG SGGQKQRIAIA AL+R P+LLLLDEATSALD SE++VQ+ LD+ A RTVV+VAHRL TVRNAD Sbjct: 22 VSFFKLFSHADLRDKMCIVFGFIFSVASGAGFPLNVLIFRSIIDQFIGP-----SFDASLIYGIVKWFAVLGACLIVLTFLQSFLFGISAQRQSRRIRVKYFKAVLRQDVPWFDTQSSGSLMNKLTQNIDNIEEGIGSKFGEFILNLSGFFCGLIIAFFVGWKLTLVACAMVPFVVTVFLFFGVSMKYFTMKELDAYSRASAISGEVLSAIRTVMAFGGEKKEFQRYSKELGAAQKMGIIKSAALGGVVGAIGLTLFSSAALIFWYGIELIITENYSGGTVVTVFINVVIGSIFLGNALPNMQYFLIAMASATEVYGLIDRVPPIDKDRSGKRIPDFTGNIIFKDVDFAYPTRPDIVVLKKFNLELKSGQTVALVGPSGSGKSTIVHMLQRFYDPIGGEIIVEGENIRDLDLKAFRAQLGCVQQEPILFEGTVEDNIRLGKLDATNEEIIEAAKMANAHDFILHLPEGYKTVLAERGAGLSGGQKQRIAIARALIRKPKLLLLDEATSALDTRSERVVQEALDQ--ASAGRTVVVVAHRLTTVRNAD 561 HSP 2 Score: 252.677 bits (644), Expect = 1.126e-68 Identity = 183/540 (33.89%), Postives = 278/540 (51.48%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFA----ILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDK--QQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSH--------NLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSY-DPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIP-ESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDP----LAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GA P L++ + + D E+MR V FA L F+ Q ++ R +RR+R F A++RQEI WFD+ Q G L L + ++S +L I+ + +++AF W+L+ + P+ + L I I K+ S +A+E +SS RTV + ++ R+ NLK+ V S+ Q G FT+G+ F+ E Y + V ++F + + + +LG + A+ A+ + + +DR P I G++P E F G++EFK+V F YPTR + +L+ F+ + G+TVA +G SG GKST++ L+QRFYDP I F G +++ + W R IG+V QEP LF SI++NI G + +EI+++ + +N +EFI + ++T +G +G+ SGGQKQR+AIA AL+R P LLLLDEATSALD SE++VQ+ LD A G RT +MVAHRL TV NAD Sbjct: 694 GAVQPSFALLYSQMFQIFTYAND-----PEKMRSQVSIFAALMVFLGCLRFLGMLGQGFFFGVSGERLTRRVRGMLFQAIMRQEIGWFDRTENQPGTLTAVLATEASKMKSLSGSQLGFIIEAFALVTMSLVIAFIYSWQLTLLMLAFYPMFILSGMLQIKRIAGEGSKETDGPSTQ--LAQEAISSDRTVFTLNLEDYFQNRFEDLLMNKKLSNLKQTILFAVLFSLTQA-GPMFCFAAAFTLGA--------FLVEHKYIEMLAVFRVFAVLNMSAQSLGRTASIGPETQRAREASKIILKTLDRTPSI-RTDDGLVPREPFRGNVEFKHVYFSYPTRKTISVLKKFSHAVNSGETVALVGESGCGKSTLLQLVQRFYDPDDFGSDSGIFFDGHNIRQLAPAWVRRQIGIVSQEPNLFDMSIRDNIAYGDNSREVTMDEIMEAARQANVHEFITTLPEGYDTSVGQKGSHLSGGQKQRVAIARALLRKPILLLLDEATSALDVESERVVQEALDS--AMGSRTCLMVAHRLSTVENAD 1214
BLAST of SMED30003432 vs. TrEMBL
Match: A0A504YDC3 (Multidrug resistance protein 1 OS=Fasciola gigantica OX=46835 GN=FGIG_06363 PE=4 SV=1) HSP 1 Score: 506.908 bits (1304), Expect = 1.476e-162 Identity = 253/547 (46.25%), Postives = 371/547 (67.82%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIK-FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 VS+++LF A D + +++ I S+ GA FPLNVLIFR +++ + P +F + ++K FA+L +C + F Q ++A RQSRR+R YF A+LRQ++ WFD Q +G L+ KLT ++++IE GI K FI +S F +I+AF GWKL+ + +P + T F +K +++K++ AYS A I+ E+LS+IRTV+A+ ++KE +RYS L A+ +G+ +S G G IG T+F+ +L+++ G+ I +Y GTV+ +F+ ++IGSI LGNA+P ++ F+ A A+A ++ +IDRVP I + G F G+I FK+VDF YPTR + +L+ FN L G+TVA +GPSGSGKSTIIH+LQRFYDP+ GEI G +++D+DL +R+ +G VQQEP LF G++++NI+LGK+DA NEEI+++ + +NA++FI+ + + T L +RGAG SGGQKQRIAIA AL+R P+LLLLDEATSALD SE++VQ+ LD+ A RTVV+VAHRL TVRNAD Sbjct: 22 VSFFKLFSHADLHDKMCIVLGSIFSVASGAGFPLNVLIFRSIIDQFIGP-----SFDASLIYGIVKWFAVLGACLIVLTFSQSFLFGISAQRQSRRIRVKYFKAILRQDVPWFDTQSSGSLMNKLTQNIDNIEEGIGSKFGEFILNLSGFFCGLIIAFFVGWKLTLVACAMVPFVVTVFLFFGVSMKYFTMKELDAYSRASAISGEVLSAIRTVMAYGGEKKEFQRYSKELGAAQKMGIIKSAALGGVVGAIGLTLFSSAALIFWYGIELIITENYSGGTVVTVFINVIIGSIFLGNALPNMQYFLIAMASATEVYSLIDRVPPIDKDQSGKGIPDFTGNIIFKDVDFAYPTRSDIVVLKKFNLELKSGQTVALVGPSGSGKSTIIHMLQRFYDPIGGEIIVEGENIRDLDLKAFRAQLGCVQQEPVLFEGTVEDNIRLGKLDATNEEIIEAAKMANAHDFILHLPEGYKTVLAERGAGLSGGQKQRIAIARALIRKPKLLLLDEATSALDTRSERVVQEALDQ--ASTGRTVVVVAHRLTTVRNAD 561 HSP 2 Score: 255.373 bits (651), Expect = 1.490e-69 Identity = 185/540 (34.26%), Postives = 279/540 (51.67%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAIL----SSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDK--QQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSH--------NLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSY-DPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIP-ESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDP----LAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GA P L++ + + D E+MR V FA+L F+ Q ++ R +RR+R F A++RQEI WFD+ Q G L L + ++S +L I+ + +++AF W+L+ + P+ + L I I K+ S +A+E +SS RTV + ++ R+ NLK+ V S+ Q G FT+G+ F+ E Y + V ++F + + + +LG + A+ A+ + + +DR P I G++P E F G++EFK+V F YPTR + +L+ F+ + G+TVA +G SG GKST++ L+QRFYDP I F G +++ + W R IGVV QEP LF SI++NI G + +EI+++ + +N +EFI + ++T +G +G+ SGGQKQR+AIA AL+R P LLLLDEATSALD SE++VQK LD A G RT +MVAHRL TV NAD Sbjct: 694 GAVQPSFALLYSQMFQIFTYAND-----PEKMRSQVSIFAVLMVFLGCLRFLGMLGQGFFFGVSGERLTRRVRGMLFQAIMRQEIGWFDRTENQPGTLTAVLATEASKMKSLSGSQLGFIIEAFALVTMSLVIAFIYSWQLTLLMLAFYPMFILSGMLQIKRIAGEESKETDGPSTQ--LAQEAISSDRTVFTLNLEDYFQNRFEDLLMNKKLSNLKQTILFAVLFSLTQA-GPMFCFAAAFTLGA--------FLVEHKYIEMLAVFRVFAVLNMSAQSLGRTASIGPETQRAREASKIILETMDRTPSI-RTDDGLVPREPFRGNVEFKHVYFNYPTRKTISVLKKFSHAVNSGETVALVGESGCGKSTLLQLVQRFYDPDDFGSDSGIFFDGHNIRQLAPAWVRRQIGVVSQEPNLFDMSIRDNIAYGDNSREVTMDEIMEAARQANIHEFITTLPEGYDTSVGQKGSRLSGGQKQRVAIARALLRKPILLLLDEATSALDVESEQVVQKALDS--AMGSRTCLMVAHRLSTVENAD 1214
BLAST of SMED30003432 vs. TrEMBL
Match: A0A4E0RE86 (ATP binding cassette subfamily B MDR TAP OS=Fasciola hepatica OX=6192 GN=D915_004337 PE=4 SV=1) HSP 1 Score: 506.908 bits (1304), Expect = 1.558e-162 Identity = 250/548 (45.62%), Postives = 371/548 (67.70%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDLTMT-FSERMRPSVIK-FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 +S+++LF A D + I +I G FPLN+LIFR ++N + T T F+ + ++ FAIL +C + F+Q + +A RQS+R+R YF A++RQ++ WFD+Q TG L++KLT ++++IE GI K FI IS F II+AF GWKL+ + IP++ F+L +KK+++K+++AY+ A GI+ E+ S+IRTVVAF ++KE++RYS L A+ +G+++S G G IG +F +LV++ G+ + + Y G+++ +F+ I++GSI LGNA+P ++ F+ A ++A ++ IDRVP I K G F G+I FK+VDF YP R +L+ FN L G+TVA +GPSGSGKST++H+LQRFYDP+ GEI G +++D+DL +R+ +G VQQEP LF G++++NI+LGK+DA NEEI+++ + +NA++FI+ + + T L +RGAG SGGQKQRIAIA AL+R P+LLLLDEATSALD SE++VQ+ LD+ A RTVV+VAHRL TVRNAD Sbjct: 22 ISFFKLFSHADARDKACIFFGSIFAIASGTGFPLNILIFRSIIN------EFTGTNFAASVIYDIVGWFAILGACLAVVSFLQSFLFATSAERQSKRIRLKYFKAIMRQDVPWFDEQSTGALMSKLTQNIDNIEEGIGTKFGEFILNISGFFCGIIIAFAVGWKLALVACCMIPLVVIVFALFGFLMKKFTLKELQAYAQASGISGEVFSAIRTVVAFGGEKKELQRYSKELGAAQKVGIQKSTALGGVMGAIGLALFCAAALVFWYGIELLLKEGYRGGSIVTVFVNIIVGSIFLGNALPSMQYFLIAMSSAAEVYGTIDRVPPIDKNKSGKHIPDFAGNIIFKDVDFAYPLRSDAIVLKKFNLELKSGQTVALVGPSGSGKSTVVHMLQRFYDPIGGEIIVEGENIRDLDLKAFRAQLGCVQQEPILFEGTVEDNIRLGKLDATNEEIIEAAKMANAHDFILHLPEGYKTVLAERGAGLSGGQKQRIAIARALIRKPKLLLLDEATSALDTRSERVVQEALDQ--ASAGRTVVVVAHRLTTVRNAD 561 HSP 2 Score: 246.128 bits (627), Expect = 2.101e-66 Identity = 167/506 (33.00%), Postives = 267/506 (52.77%), Query Frame = -1 Query: 1 ERMRPSVIKFA----ILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDK--QQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSL-----VYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLA----GEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1467 ++MR V FA ++ F+S Q ++ R +RR+R F A+++QEI WFD+ Q G L L + ++S +L ++ I V +++ F W+L+ + P+ T + I + + K+ S +A+E + S RT+ + ++ RY ++L L K+S + + + F++ G + + +G + V ++F + + +LG + A+ A+ + Q++DR P I + V E F G +EFK + F YPTR + +L+NF+ + G+TVA +G SG GKST++ L+QRFYDP++ I F G +++ + W R IG+V QEP LF SI++NI G + +EI+++ + +N +EFI + + T G +G+ SGGQKQR+AIA AL+R P LLLLDEATSALD SE++VQ LD A G RT ++VAHRL TV NAD Sbjct: 721 DKMRSQVGLFAGLMVLMGVLRFLSMLGQGFFFGVSGERLTRRVRCKLFEAVMKQEIGWFDRTENQPGVLTVLLATEASKLKSISGAQLGYIVEAIVMVVMSLVITFIYSWQLTLLMLAFYPLFVLTGMIQIQRMSGGNSKKTDITSTR--VAQEAIGSDRTLFTLTLEDYFYSRYENSL-----LHNKKSNLKKIAVYAVLFSLTQAGPMFCFAAAFALGAYLVGRHDIQMLAVFRVFSVQNLTAQSLGRTASYGPESLRAQNASKAILQLLDRNPSIRTDEGSVPQEPFKGHVEFKRIYFSYPTRKTLVVLKNFSHVVNPGETVALVGESGCGKSTLLQLVQRFYDPISVGSDSGIFFDGHNIRQLAPAWVRRQIGIVSQEPNLFDMSIRDNIAYGDNSREVTIDEIIEAARQANIHEFITTLPEGYETSAGQKGSRLSGGQKQRVAIARALLRKPILLLLDEATSALDVESERVVQDALDS--AMGSRTCLVVAHRLSTVENAD 1217
BLAST of SMED30003432 vs. Ensembl Cavefish
Match: abcb5 (ATP-binding cassette, sub-family B (MDR/TAP), member 5 [Source:ZFIN;Acc:ZDB-GENE-030131-6414]) HSP 1 Score: 439.884 bits (1130), Expect = 2.530e-140 Identity = 228/570 (40.00%), Postives = 349/570 (61.23%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVN-LLVSPRDLTMT----FSERMRPSVIK----------------FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEG--SYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDR-VPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V ++QLFR+AT +++L++++ + + G P+ ++F + + ++S + L +T FS + + F L + + G Q+ LTA RQ++R+R YF+A+L Q + WFD G+L T+LTDD+ +I G+ DK+ F+Q +F+ I+ F GWKL+ + P++A + ++ + + K++ AY+ AG +AEEIL +IRTVVAF+ Q+K ++Y NL A+ GVK+++ + G+ F IF +L ++ G + +Y G VI +F +++IG+ +LG P LE+ A+ AAY ++ ID P S + G P+S GDIEF+NV F YP+R V ILQ + +P+GKT+A +G SG GKST I LLQRFYDP AGE++ G D++ +++ W R ++G+V QEP LF +I ENI+ G+ DA +++I ++ +++NAYEFI K NT +G+RGA SGGQKQRIAIA ALV+NP++LLLDEATSALD SE +VQ LDK A RT +++AHRL T+R AD Sbjct: 4 VGFFQLFRYATCLEVLMMVLGLGCAALHGITLPIMCVVFGQMTDSFVLSGQQLNLTGLGNFSTNLSSGCVAIPGIDIEASMSQHAYYFVALGAAVLLLGTFQVTLFLLTATRQTKRIREKYFHAVLHQPMAWFDTHPIGELNTRLTDDINTINDGLGDKICIFVQFFCTFLAGFIIGFIYGWKLTLVIMSVSPLLAASAAVWSKILATLTSKELSAYAKAGAVAEEILVAIRTVVAFNGQQKAAEKYEKNLITAKDFGVKKAVTTNVSMGLTQFFIFGAYALAFWYGTKLTVDDPVNYSIGKVIIVFFSVMIGAFSLGQGAPNLESVAKARGAAYSIYNTIDMPRPIDSSSEEGYKPDSVRGDIEFRNVHFSYPSRKDVKILQGMSLKVPHGKTIALVGASGCGKSTTIQLLQRFYDPEAGEVTLDGRDIRSLNVRWLRENMGIVSQEPVLFGTTIAENIRYGREDATDQDIDRAVREANAYEFISKLPDGLNTMVGERGAQLSGGQKQRIAIARALVKNPKILLLDEATSALDTQSEAIVQAALDK--ARAGRTTIVIAHRLSTIRTAD 571 HSP 2 Score: 318.546 bits (815), Expect = 2.271e-95 Identity = 182/528 (34.47%), Postives = 290/528 (54.92%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSP-----RDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQT--GQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G +P ++F ++ + P R + FS + F ++ + F++ F Q + + RLRS F A+LRQ+I WFD G L TKL D ++ +L I + V +I+AF W+L+ + PI+ + + + ++ K A ++G I+ E + + +TVV+ + ++ ++++ +L + + ++ G+ + + V + V+ G I V +F IV ++++G + +F AKAAA + ++++ P+I + + G P +F GDIEF++V F YPTRP + ILQ N ++ G+T+A +G SG GKST I LL+RFY+P G++ G D + ++L W RS +G+V QEP LF +I ENIQ G + EE+V++ +N + FI +K+NT +GD+G SGGQKQRIAIA ALVR P++LLLDEATSALD SEK+VQK LD+ A RT +++AHRL TV+NAD Sbjct: 714 GGVYPAVAILFAKIIGVFSEPDPEVKRQKALMFS-------LLFLLVGAVAFLTFFFQGYMFGKSGEILTMRLRSQAFKAILRQDISWFDDHNNAVGVLTTKLATDASLVKGAAGSRLGLATNTICALVIAMIVAFFHSWQLTLMILACTPILTGANFIQMRAMAGHTSKDQSALEMSGRISTETVENFKTVVSLTKEDVFFRKFNDSLNKPYRSALCKAPIYGITFALAQAIPYFVNAAVFRFGSWLIAHCHTQFENVFLVFSVIVFAAMSIGQSSSFAPDFAKAKAAAGRILALLEKTPEIDIYSEAGDKPINFKGDIEFRDVHFFYPTRPNIKILQGLNVSVTQGQTLALVGGSGCGKSTSIQLLERFYNPAGGQVFADGMDTRGLNLAWLRSQLGLVSQEPILFDCTITENIQYGDNSRVVSQEEVVEAAISANIHNFISDLPEKYNTRVGDKGTQLSGGQKQRIAIARALVRKPKVLLLDEATSALDTESEKIVQKALDE--ARKGRTCIVIAHRLTTVQNAD 1232
BLAST of SMED30003432 vs. Ensembl Cavefish
Match: abcb5 (ATP-binding cassette, sub-family B (MDR/TAP), member 5 [Source:ZFIN;Acc:ZDB-GENE-030131-6414]) HSP 1 Score: 422.935 bits (1086), Expect = 8.789e-135 Identity = 210/483 (43.48%), Postives = 310/483 (64.18%), Query Frame = -1 Query: 1 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEG--SYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDR-VPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1440 F + + + G Q++ LTA RQ++R+R YF+A+L Q++ WFD G+L T+LTDD+ +I G+ DK+ F+Q F+ II+ F GWKL+ + P++A + ++ + + K++ AY+ AG +AEEIL +IRTVVAF+ Q+K +++Y NL++A+ GVK++I + G+ F IF +L ++ G + +Y G VI +F +++IG+ +LG P LE+ A+ AAY ++ ID P S K G P+S GDIEFKN+ F YP+R V ILQ + +P+GKT+A +G SG GKST I LLQRFYDP AGE++ G D++ +++ W R ++G+V QEP LF +I ENI+ G+ DA +++I ++ +++NAYEFI K NT +G+RGA SGGQKQRIAIA ALV+NP++LLLDEATSALD SE Q A RT +++AHRL T+R AD Sbjct: 25 FVGIGAGVLLLGTFQVMLFLLTATRQTKRIREKYFHAVLHQQMAWFDTHPIGELNTRLTDDINTINDGLGDKICIFVQFFCRFLAGIIIGFIYGWKLTLVIMSVSPLLAGSAAVWSKILATLTGKELSAYAKAGAVAEEILVAIRTVVAFNGQQKALEKYEKNLEDAKNFGVKKAITTNVSMGITQFFIFGTYALAFWYGTKLSVDEPENYSIGKVITVFFSVMIGAFSLGQGAPNLESVAKARGAAYSIYNTIDMPRPIDSSSKEGHKPDSVRGDIEFKNIHFSYPSRKDVKILQGMSLKVPHGKTIALVGASGCGKSTTIQLLQRFYDPDAGEVTLDGRDIRSLNVRWLRENMGIVSQEPVLFGTTIAENIRYGREDATDQDIDRAVREANAYEFISKLPDGLNTMVGERGAQLSGGQKQRIAIARALVKNPKILLLDEATSALDTQSES--QGNFPN--ARAGRTTIVIAHRLSTIRTAD 503 HSP 2 Score: 320.857 bits (821), Expect = 1.194e-96 Identity = 180/528 (34.09%), Postives = 290/528 (54.92%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVS-----PRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQT--GQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GA +P ++F ++ + R TM FS + F ++ + FI+ F Q + + RLRS F A+LRQ+I WFD G L TKL D ++ ++ + + +I+AF W+L+ + +P + + + ++ ++ K A +G I+ E + + +TVVA + ++ ++++ +L E + ++ G+ + + V + V+ G I V +F I+ ++++G + +F AK AA + ++++ P+I + + G P +F GDIEF + F YPTRP + ILQ N ++ G+T+A +G SG GKST I LL+RFY+P G++ G D + ++L W RS +G+V QEP LF +I ENIQ G + EE+ ++ +++N +EFI+ +++NT +GD+G SGGQKQRIAIA ALVRNP++LLLDEATSALD SEK+VQK LD A RT +++AHRL TV+NAD Sbjct: 607 GAVYPCVGILFAKIIGVFAETDPEVKRQKTMMFS-------LLFLLVGAVAFITYFFQGYMFGKSGEILTMRLRSQAFKAILRQDISWFDDHNNAVGVLTTKLATDASLVKGVTGSRIGLATSSVCALGISVIIAFCFSWQLTLLILACVPFLTGANFIQMRAMQGHASKDQSALETSGKISTETVENFKTVVALTKEDVFFRKFNDSLAEPYKSALCKAPIYGITFALAQAIPYLVNAAVFRFGAWLIAHCHTQYENVFLVFSVIIFAAMSIGQSSSFAPDFAKAKVAAGRILSLLEKTPEIDIYSEAGDKPMNFKGDIEFHELHFSYPTRPNIKILQGLNVSVRQGQTLALVGGSGCGKSTSIQLLERFYNPAGGQVFADGMDTRMLNLAWLRSQLGLVSQEPILFDCTITENIQYGDNSRVVSQEEVEEAAKNANIHEFILNLPERYNTRVGDKGTQLSGGQKQRIAIARALVRNPKVLLLDEATSALDTESEKIVQKALDD--ARQGRTCIVIAHRLTTVQNAD 1125
BLAST of SMED30003432 vs. Ensembl Cavefish
Match: abcb5 (ATP-binding cassette, sub-family B (MDR/TAP), member 5 [Source:ZFIN;Acc:ZDB-GENE-030131-6414]) HSP 1 Score: 417.927 bits (1073), Expect = 3.325e-132 Identity = 218/543 (40.15%), Postives = 334/543 (61.51%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVN-LLVSPRDLT----------------MTF-SERMRPSVIK----FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGL-LFIYE-GSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDR-VPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GAA P+ ++F + + ++S + L MTF E + S+ K F + + + G Q++ +T+ RQ++R+R YF+A+L Q + WFD +L T+LTDD+ +I G+ DK+ F+Q F+ I+ F GWKL+ + P++A + +L + + +++ AY+ AG ++ EIL +IRTVVAF+ ++K +++Y NL EA+ GV+++I G+ F +F+ +L ++ G L + E +Y G V+ +F +++IG+++LG P LE+ A+ AAY ++ ID P S G P+S GDIEFK + F YP+R V ILQ + +P+GKT+A +G SG GKST I LLQRFYDP AGE++ G D++ +++ W R ++G+V QEP LF +I ENI+ G+ DA +++I ++ +++NAYEFI K NT +G+RGA SGGQKQRIAIA ALV+NP++LLLDEATSALD SE +VQ LDK A RT +++AHRL T+R AD Sbjct: 12 GAALPIMFIVFGSMTDSFILSGQQLNFTGNYTFNLTKRSSDCMTFPGEDIEGSMTKNAYYFVGIGAGVLLLGTFQVMLFVITSTRQTKRIREKYFHAVLHQPMAWFDTHPIRELNTRLTDDINTINDGLGDKICIFVQYFCRFLAGFIIGFIYGWKLTLVIMSVSPLLAGSAALCSKILATLTGRELSAYAKAGSVSAEILGAIRTVVAFNGRQKALEKYETNLLEAKNFGVRKAITTNAAMGITQFLLFSTFALAFWYGTKLSVDEPENYSIGKVLTVFFSVMIGALSLGQGAPNLESIAKARGAAYSIYSTIDMPRPIDSSSIKGYKPDSVSGDIEFKKIHFSYPSRKDVKILQGMSLKVPHGKTIALVGASGCGKSTTIQLLQRFYDPDAGEVTLDGRDIRCLNVRWLRENMGIVSQEPVLFGTTIAENIRYGREDATDQDIDRAVREANAYEFISKLPDGLNTMVGERGAQLSGGQKQRIAIARALVKNPKILLLDEATSALDTQSEAIVQAALDK--ARAGRTTIVIAHRLSTIRTAD 552 HSP 2 Score: 326.25 bits (835), Expect = 3.202e-98 Identity = 186/531 (35.03%), Postives = 294/531 (55.37%), Query Frame = -1 Query: 1 CVGAA-FPLNVLIFRDVVNLLVS-----PRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDK--QQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1560 CVG +P ++F ++ + R +M FS + F ++ + F++ F Q + + + RLRS F A+LRQ+I WFD G L TKL D ++ +L+ S +I+A W+L+ + +P + + +K ++ K +A +G I+ E + + RTVVA + +E ++++S +L E + ++ G+ + + + V + + G I + +F +V+ ++ +G +F AKAAA + ++++ P+I + GV P +F GDIEF +V F YPT+P V ILQ N ++ G+T+A +G SG GKST I LL+RFY+P G++ G D + ++L W RS +G+V QEP LF +I ENIQ G + EE+V++ + +N +EFI+ +++NT +GD+G SGGQKQRIAIA ALVRNP++LLLDEATSALD SEK+VQK LD+ A RT +++AHRL TV+NAD Sbjct: 689 CVGGGVYPCVGILFAKIIGVFAELDPEVKRQKSMMFS-------LLFFLVGTMAFLTYFFQGYMLGKSGESLTMRLRSQAFKAILRQDISWFDDYDNAVGVLTTKLATDASLVKGAAGSRLSLATSSFCSLGVSVIVALCFSWQLTLLILACVPFLTGAMFIQTRSMKGHASKDQRALETSGKISTETVENFRTVVALTKEEVFMQKFSDSLSEPYKSALWKAPLYGMSFALAQASSYFVRAAFFRFGAWLIAHCYAQYEDIYLVFSVLVLSTMNVGQTSSANLDFAKAKAAAGRIIALLEKKPEIDIYSDAGVKPTNFRGDIEFHDVHFSYPTQPDVRILQGLNVSVRQGQTLALVGGSGCGKSTSIQLLERFYNPAGGQVFADGMDTRGLNLAWLRSQLGLVSQEPILFDCTITENIQYGDNSRVVSQEEVVEAAKKANIHEFILNLPERYNTRVGDKGTQLSGGQKQRIAIARALVRNPKVLLLDEATSALDTESEKIVQKALDE--ARKGRTCIVIAHRLTTVQNAD 1210
BLAST of SMED30003432 vs. Ensembl Cavefish
Match: abcb11a (ATP binding cassette subfamily B member 11 [Source:NCBI gene;Acc:103030940]) HSP 1 Score: 417.927 bits (1073), Expect = 8.401e-132 Identity = 239/586 (40.78%), Postives = 356/586 (60.75%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISG--------------------------------------FIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMG-LLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V ++QLFRFAT D+++++V + ++ GAA PL +L++ + N+ V+ + E P K I ++ T+ +G + Q+ AARQ++R+R YF ++ EI WFD G+L TK++DD+ I + I+D++ FI++IS+F+ ++ F GWKL+ + P++ LM + + + ++++AY+ AG IA+E+LSSIRTV AF ++KE +RY NL+EA+T GVK+ G+ G + IF +L ++ G L I PGT+IQ+F ++IG++ LG A P LE F + +AAA +F IDR+P+I + G E GDIEF +++F YP+RP V IL N N + G+T AF+GPSGSGKST + L+QRFYDP G ++ G D++ +++ W RS IG+V+QEP LF+ SI ENI+ G+ EEI+++++++NAY FIM QKF+T +G+ G SGGQKQRIAIA ALVRNP++LLLD ATSALDN SE +VQ+ LDK A RT + +AHRL T+RNAD Sbjct: 31 VGFFQLFRFATCTDIVMMVVGGLCALVHGAASPLMLLVYGMMTNIFVA---YELEVQELADPD--KTCINNTVTWTNGSVVELEGNTVYCGVDIEAQMTMFAYYYIGIGLGVLILSYFQIALWVSAAARQTQRIRKTYFRKIMCMEIGWFDCTSVGELNTKISDDINKINNAIADQVTIFIERISTFIFGFMVGFVGGWKLTLVIIAVSPLIGLAAGLMAMAVARLTGRELQAYAKAGAIADEVLSSIRTVAAFGGEDKETERYDKNLEEAQTWGVKKGTIIGIFQGYLWCIIFLCYALAFWYGSKLVIDTKELTPGTLIQVFFGVLIGAMNLGQASPCLEAFASGRAAAKSIFDTIDRIPKIDCFSEEGHKLEKVKGDIEFHSIEFNYPSRPDVKILDNLNLEVKAGETTAFVGPSGSGKSTAVQLIQRFYDPSQGMVTLDGHDIRSLNIQWLRSLIGIVEQEPVLFATSISENIRYGRPGVTMEEIIQASKEANAYNFIMDLPQKFDTLVGEGGGQMSGGQKQRIAIARALVRNPKILLLDMATSALDNESEAVVQEALDK--ARVGRTTITIAHRLSTIRNAD 609 HSP 2 Score: 296.975 bits (759), Expect = 1.722e-87 Identity = 183/527 (34.72%), Postives = 289/527 (54.84%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDK--QQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRS----ICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G+ P+ L+F ++ + RDL +++ I F I+ +F S F+Q + + R +RRLR F A+L+QE+ WFD G L T+L D ++ ++ + +++ I+A+T WKLS + + +P++ + + ++ + KA AG ++ E +++IRTV + +++ V Y L+ K++ IC VI + Y G L YEG + V ++ IV ALG A ++ AK AA F+++DRVP+I+ ++K G + F G +EFKN F YP+RP + +L+ + G+T+AF+G SG GKST + LL+RFYDP G++ G D+++ + RS IG+V QEP LF +I ENIQ G + +EIV +++ + +EF+M K+ T +G +G+ S GQKQRIAIA A++RNP++LLLDEATSALD SEK VQ LD+ A RT +++AHRL T++ AD Sbjct: 756 GSVNPIYALLFSQILGTF-ALRDLEEQ-RDQINGVCILFVIVGCMSFFSQFLQGYAFAKSGERLTRRLRKVGFQAMLQQEVGWFDDPTNSPGALTTRLATDASMVQGATGSQIGMIVNSLTNIGASFIIAYTFSWKLSLVVTGFLPLIGLSGVFQAKMLTGFANEDKKALEAAGQVSSEAMANIRTVAGLAKEKQFVDLYEQQLEAPYRAAKKKANIYAICFAFAQCVI---FMAYAASFRYGGYLVTYEGLHYV-VVFRVIAAIVTSGTALGKASSFTPDYAKAKIAAAQFFKLLDRVPRININQKDGKRWDHFKGRVEFKNCTFTYPSRPSIQVLRGLEVAVSPGQTLAFVGSSGCGKSTSVQLLERFYDPDQGQVLIDGHPSHDVNVPFLRSQIGIVSQEPVLFDCTIAENIQYGDNSRLISMDEIVDASKKAYLHEFVMSLPDKYETQVGAQGSQLSRGQKQRIAIARAIIRNPKILLLDEATSALDTESEKTVQAALDE--ARRGRTCIVIAHRLSTIQTAD 1274
BLAST of SMED30003432 vs. Ensembl Cavefish
Match: abcb11b (bile salt export pump-like [Source:NCBI gene;Acc:103028308]) HSP 1 Score: 412.92 bits (1060), Expect = 1.015e-129 Identity = 227/584 (38.87%), Postives = 352/584 (60.27%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIF---------------------RDVVNLLVSPRDLT---------------MTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEG-SYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISH-KKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 + ++QLFRFAT ++ +++ + ++ G+A PL +L+F + +N + R+L+ + M + + S FI G++Q+ +AARQ + +R YF ++R EI WFD G+L T+++DD+ I I+D+++ FIQ+ ++FV ++ F GWKL+ + P++ +LM F+ K + ++++AY+ AG +A+E+LSSIRTV AF ++KEV+RY HNL A+ G+++ + G +G + F IF +L ++ G + + Y PGT++Q+F ++I ++ LG A P LE F + AA +F+ IDR P+I + G + GD+EF NV F YP+RP V IL N + G+T AF+GPSG+GKST I LLQRFYDP G ++ G D++ +++ W RS +G+V+QEP LF+ +I ENI+ G+ +E+I+K+ +++NAY FIM QKF+T +G+ G SGGQKQRIAIA ALVRNP++LLLD ATSALDN SE +VQ+ LDK RT + +AHRL T++NAD Sbjct: 56 IGFFQLFRFATCREVCMMVCGSVCAVLHGSAQPLMLLVFGLLTDTFIEYDIELNELTDPEKRCINNTIQWRNLSAEENLELNMTRTCGLLDIEYEMTNFAYYYVGIGSGVFILGYLQISLWVTSAARQIQIIRRLYFGKVMRMEIGWFDCNSVGELNTRMSDDINKINDAIADQVSIFIQRFTTFVCGFLMGFVRGWKLTLVIISVSPLIGVGAALMALFVAKLTGRELQAYAKAGAVADEVLSSIRTVAAFGGEKKEVERYDHNLISAQRWGIRKGLIMGFFTGYLWFIIFLCYALAFWYGSSLVVDTLEYSPGTLLQVFFGVLIAALNLGQASPCLEAFAAGRGAATTIFETIDREPEIDCLSEAGYKLDRVKGDLEFHNVTFHYPSRPEVKILDQLNLQVKTGETTAFVGPSGAGKSTAIQLLQRFYDPKEGMVTLDGHDIRGLNIQWLRSLMGIVEQEPVLFATTIAENIRYGRPGVSHEDIIKAAKEANAYNFIMDLPQKFDTLVGEGGGQMSGGQKQRIAIARALVRNPRILLLDMATSALDNESEAIVQEALDKV--RLGRTTISIAHRLSTIKNAD 637 HSP 2 Score: 269.626 bits (688), Expect = 9.673e-78 Identity = 164/485 (33.81%), Postives = 265/485 (54.64%), Query Frame = -1 Query: 1 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQT--GQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1440 F ++ +F + +Q + S + +RRLR F A+L QE+ WFD + G L T+L D ++ ++ + +++ II++F WKLS + +P +A + + ++ + +A AG I+ E L++IRT+ + + V+ Y L+ +K++ G G +F S Y G + V ++ IV ALG A ++ AK +A FQ++DR P+IS + G F GDIEF + F YP+RP + +L ++ G+T+AF+G SG GKST + LL+RFYDP G++ G + I++ + RS IG+V QEP LF SI ENI+ G + ++++ +++ + ++F+M +K+ T +G +G+ S GQKQRIAIA A++R+P++LLLDEATSALD SEK VQ+ LDK A RT +++AHRL T++N+D Sbjct: 829 FVLVGVISFFTQMLQGYSFSKSGELLTRRLRRLGFQAMLGQEVGWFDDHRNSPGALTTRLATDASQVQGATGSQIGMIVNSLTNIGVAIIISFYFSWKLSLVIMCFLPFLALSGGFQAKMLTGFAKQDKQAMEAAGQISGEALNNIRTIAGLGKERRFVEMYEAQLEAPYRAALKKANVYGACYGFAQCVVFMANSASYRFGGYLVRHEGLHFSLVFRVISAIVTSGTALGRASSYTPDYAKAKISAARFFQLLDRTPKISVYSDKGDKWNHFKGDIEFIDCKFTYPSRPDIQVLNGLTVSVKPGQTLAFVGSSGCGKSTSVQLLERFYDPDFGKVLIDGRESSRINVQFLRSKIGIVSQEPILFDCSILENIRYGDNKRVLSMDDVISASKKAQLHDFVMSLPEKYETNVGSQGSQLSRGQKQRIAIARAIIRDPKILLLDEATSALDTESEKTVQEALDK--AREGRTCIVIAHRLSTIQNSD 1311
BLAST of SMED30003432 vs. Ensembl Sea Lamprey
Match: abcb11b (ATP-binding cassette, sub-family B (MDR/TAP), member 11b [Source:ZFIN;Acc:ZDB-GENE-050517-14]) HSP 1 Score: 395.586 bits (1015), Expect = 4.181e-124 Identity = 228/579 (39.38%), Postives = 346/579 (59.76%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLV----------SPRDLTMTFS-----------------ERMRPSVIKFAI----LSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGL-LFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V QLFRFA G D+++++ + +I GAA P +L+F + + + P + + S + + FA + + G++Q+ + AARQ R+R +F+ ++R EI WFD G+L T+++DD+ I I+DK++ FIQ+ ++FV ++ F GWKL+ + P++ +LM F+ + + +++KAY+ AG +AEE+LSSIRTV AF ++KE RY NL A+ G+++ + G G + F IF +L ++ G L + E Y PGT++Q+F +++G+I LG A P LE F + + AA +F +IDR P I G I + GDIEF NV F YPTR + L +FN + G+T AF+GPSG+GKST + L+QRFYDP G+++ G D++ ++L W RS IGVV+QEP LF+ +I ENI+ G+ + E+ ++ + +NAY FIM+ KF+T +G+ G SGGQKQRIAIA ALVRNP++LLLD+ATSALDN SE +VQ LDK + +G T + +AHRL T+ +AD Sbjct: 51 VGLCQLFRFAKGGDIVLMVTGALGAIVHGAALPFMLLVFGRMADAFIEYDLETQELQDPNKMCLNNSILWVNGTTIPNATACGHTDIEVELTTFAFYYLGIGCVVLLVGYLQICFWVMAAARQVLRIRQAFFHNIMRMEIGWFDMNSVGELNTRISDDINKINDAIADKMSIFIQRFTTFVCGFLIGFLNGWKLTLVILAVSPLLGLGGALMGSFVARMTGRELKAYAKAGAVAEEVLSSIRTVAAFGGEKKEENRYDKNLVMAQKWGIRKGMILGFFQGYMWFIIFLCYALAFWYGSNLVLEEEEYSPGTLLQVFFGVLVGAINLGQASPCLEAFASGRGAATHVFNIIDREPIIDCMSDDGNILQKVKGDIEFHNVKFSYPTRLDLTALHSFNLKVNAGETTAFVGPSGAGKSTAMQLIQRFYDPQEGKVTLDGHDIRSLNLRWMRSLIGVVEQEPILFATTIAENIRYGRDNVTVSEVEQAARRANAYNFIMELPHKFDTMVGEGGGQMSGGQKQRIAIARALVRNPRILLLDQATSALDNESEAVVQSALDK-VRKGC-TTISIAHRLSTIHSAD 627 HSP 2 Score: 265.388 bits (677), Expect = 4.510e-77 Identity = 171/537 (31.84%), Postives = 275/537 (51.21%), Query Frame = -1 Query: 1 VGAAF-----PLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNL--------KEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGK--MDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1557 VGAA P+ ++F +++ P + + + + F ++ +F++ F+Q S + +RRLR F A+LRQ++ WFD K G L T+L D ++ + F ++ + W+ TF + I+ Y + A + E I++ IRTV + VK+Y+ +L ++A G S Q + FT + Y G L ++G P V ++F +V ALG A ++ AK +A LF++ DR P I S GV + F GD+ F N F YP+RP +L + ++ G+T+A +G SG GKST + LL+RFYDP G++ G D + +++ + RS IG+V QEP LF SI +NI+ G + +E++ +++ + ++F+M +K+ T +GD+GA S G+KQR+AIA A++R+P++LLLDEATSALD SE+ VQ LD+ A RT +++AHRL T++NAD Sbjct: 759 VGAAINGGIQPVFAILFSEILGTFTLPTEEEQ--RNMINLTCLLFVLIGIVSFVTYFLQGYMFSKSGELLTRRLRRCGFTAMLRQDVGWFDDLKNSPGALTTRLATDASQVQGVKICYVFEFHSRMFFSFSSSCCCCSHRWERQ------------TFIMNIYIRTPYGEDNRTRNARAHFVNESIVN-IRTVAGLGKERTFVKQYTDSLTVPHRAAIRKANVFGATFSFSQSV-------IFFTYAASFRYGGFLVAHDGLKFP-LVFRVFSALVFSGTALGRASSYAPDYAKAKISAARLFKLFDRTPAIDSSPDKGVSWDGFRGDVTFTNCTFTYPSRPDTQVLNGLSVSVQPGQTLALVGTSGCGKSTSVQLLERFYDPDGGQVLIDGRDSRTVNVGFLRSKIGIVSQEPVLFDCSIADNIRYGANFRELTWDEVINASKAAQLHDFVMGLPEKYETNVGDKGAQLSRGEKQRVAIARAIIRDPRILLLDEATSALDTESEQTVQSALDQ--ARQGRTCIVIAHRLSTIQNAD 1270
BLAST of SMED30003432 vs. Ensembl Sea Lamprey
Match: ABCB1 (ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40]) HSP 1 Score: 313.153 bits (801), Expect = 4.306e-95 Identity = 168/383 (43.86%), Postives = 237/383 (61.88%), Query Frame = -1 Query: 1 PIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEG-SYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRV----PQISHK---KHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1125 P++A + L + ++ +++ AYS AG +AEE+LS+IRTV+AF QEKE+KRY NL EA +G+K++I L G F ++ SL ++ G + E SY G V+ +F ++IG+ +G A P LE A+ AAY +F++IDR P +H ++ F ++ F +L+ N + G+TVA +G SG GKST I LLQRFYDP G I G D++ ++L R IGVV QEP LF+ +I ENI+ G E+I ++ +++NAY+FI + ++FNT +GDRGA SGGQKQRIAIA AL+RNP+LLLLDEATSALD SE +VQ+ LDK A RT +++AHRL T+RNAD Sbjct: 9 PVLAISAGLWSKILTSFTNRELLAYSKAGAVAEEVLSAIRTVMAFGGQEKELKRYDKNLVEARNIGIKKAITTNLSIGFTMFIVYASYSLAFWYGSRLVLEDTSYTIGNVMIVFFAVIIGAFGIGQAAPFLEAISVARGAAYTIFEIIDRTIHMYPFNTHNSSLRNRKRCTWFREHTLVNSIAF-------CQVLKGVNLQVKSGQTVALVGSSGCGKSTTIQLLQRFYDPQQGTIMVDGRDVRTLNLRSLRQLIGVVSQEPVLFATTIAENIRFGHEKVTMEDIERAARNANAYDFISQMPERFNTLVGDRGAQLSGGQKQRIAIARALIRNPKLLLLDEATSALDGESEAIVQEALDK--AREGRTTIVIAHRLSTIRNAD 382 HSP 2 Score: 310.457 bits (794), Expect = 3.913e-94 Identity = 181/523 (34.61%), Postives = 283/523 (54.11%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GA P +IF ++ + + DL + S++ F +L +F++ F+Q + + +LRS A+LRQ++ WFD K TG L T+L D ++ +LA Q I++ I+++F GW+L+ + +P + L + + + + K AG IA E + +IRTV + + + K Y +L+ K+S GL G ++ + + G + G + V +F IV G++A+G ++ AK +A LF + +P I S+ G E G++EF++V F YP RP V +L+ + + G+T+A +G SG GKST + LL+RFYD L+G + G D++ + + W R+ +G+V QEP LF S+ ENI G I +EIV + + +N + FI +K+NT +GD+G SGGQKQRIAIA ALVR P++LLLDEATSALD SEK+VQ+ LD+ A RT +++AHRL TV+ AD Sbjct: 506 GALQPAFAVIFSRIIGVF-AETDLVKREEQSNLYSLL-FLVLGIVSFVTFFLQGFLFGRSGELLTMKLRSMGLRAMLRQDMMWFDDPKNSTGALTTRLATDASQVQGATGARLATIAQNIANMGTAIVISFVYGWELTLLILAIVPFVGAAGFLEMQALTGQANRDKKLLEEAGKIATEAVENIRTVASLTRERTLEKIYQDSLEGPAKTAKKKSQFYGLTYGFSQGVVYLAQAAAFRFGAFLVTAGRMEFENVFLVFSAIVFGAMAVGQTSSFAPDYAKAKTSANHLFYLFQLIPAIDSYSDEGEKLEDCEGNVEFQSVGFNYPMRPNVEVLKGLSLKVENGQTLALVGSSGCGKSTSVQLLERFYDTLSGNVLIDGKDVRSLHIQWLRAQMGIVSQEPVLFDCSMAENIAYGDNSRIVPQDEIVAAARAANIHTFIDSLPEKYNTKVGDKGTQLSGGQKQRIAIARALVRQPKILLLDEATSALDTESEKIVQEALDR--AREGRTCIVIAHRLSTVQTAD 1024
BLAST of SMED30003432 vs. Ensembl Sea Lamprey
Match: abcb8 (ATP-binding cassette, sub-family B (MDR/TAP), member 8 [Source:NCBI gene;Acc:548340]) HSP 1 Score: 298.13 bits (762), Expect = 4.395e-93 Identity = 176/493 (35.70%), Postives = 281/493 (57.00%), Query Frame = -1 Query: 1 VIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYS----HNLKEAETLGVKRSICQGLGSGVIGF----TIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPE-SFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSH-IGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1449 ++ + + TF G+I + +S R + +R + F AL+RQ++ +FD +TG LV +LT DV+ +S ++ ++ ++ VGC+ + KL+ + + + M +L+ F++K S + + S A G+A+E L ++RTV AF+ ++ + ++Y+ + K E LG+ +I QGL + V+ TIF GSL+ L PG ++ + ++ + + + +A LF+ ++ P I + G+IP S G + F NV F YPTRPG +L NFN LP +T+A +G SG GKST+ LL+RFYDP +G I+ G DL+ +D +W R IG + QEP LF +I ENI+ GK A ++E+ + + +NA +FI +NT +G+RGA SGGQKQR+AIA AL++ P +L+LDEATSALD +E VQ+ L++ A RTV+++AHRL TV A+ Sbjct: 109 LVMYGFQGALTF--GYIAL--LSQVGERIAASMRKSLFEALIRQDVAFFDANRTGHLVNRLTSDVQEFKSSFKLVISQGLRSVTQTVGCVASLYLISPKLTGLMVVVMTAMVGGGALIGSFLRKLSRRAQEQISKATGVADETLGNVRTVRAFAMEDSKSEQYAVEVDKSCKMNEDLGIGIAIFQGLSNIVLNCIVLGTIFVGGSLMAGEEL--------SPGELMSFLVASQTVQRSMASVSILFGQMVRGLSAGARLFEYMELEPSIPVRGGGIIPHHSCLGHVRFNNVTFSYPTRPGQVVLHNFNLNLPPSQTIAIVGLSGGGKSTVAALLERFYDPASGSITLDGKDLRTLDPSWLRGRVIGFINQEPVLFGTTIIENIRFGKPGATDDEVYAAARLANADDFIRSFPDGYNTVVGERGATLSGGQKQRVAIARALIKQPAVLVLDEATSALDAEAEGAVQEALER--AAHGRTVLVIAHRLSTVAGAN 587
BLAST of SMED30003432 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001786.1 (pep scaffold:Pmarinus_7.0:GL477870:201625:214977:-1 gene:ENSPMAG00000001622.1 transcript:ENSPMAT00000001786.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 291.197 bits (744), Expect = 3.872e-92 Identity = 164/451 (36.36%), Postives = 259/451 (57.43%), Query Frame = -1 Query: 1 QEICWF--DKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIM--ATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKR----SICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI--NEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1320 QEI WF K TG L +L+ D ++ + +Q +S +++A GWKL+ + +P M A ++ + +IK +AY A I+ E + +IRTV + +EK + L E + +R S+ G G++ F + V+ +G + +G V ++F I+ G++A+G A+ M N+ AK +A + ++ R I S+ + G+ P++F G+++ V F YPTRP +L+ + + G+T+A +GPSGSGKSTI+ LL RFYD AG++ +G +++ ++L W R +GVV QEP LF SI ENI G + +E+V + + +N ++F+ Q ++T +G+RGA SGGQKQR+AIA AL+R+P++LLLDEATSALD SEK+VQ L+K A+ RT +++AHRL TVR AD Sbjct: 7 QEIRWFYNHKNNTGALTAQLSTDAAQVQGATGRRAGMLVQNVSGLATGLLIALLVGWKLALLMLAFMPFMVGAGLVQSVLQGSEATTIK--RAYEQASKISTEAVQNIRTVASLCLEEKFSGMFEQCLLEPYRVIKRRGYLFSVTFGFTQGILCFAY----AAVFRLGGFLVAQGELTFQDVYKVFGAIIFGALAVGQAMAMAPNYGRAKVSAARILALLRREMAIDSYSEGGIQPDAFDGELQLSGVHFRYPTRPHAEVLRGVSLRVAPGQTLALVGPSGSGKSTIMQLLLRFYDSSAGQLLLNGVEVRQLNLGWLRRQLGVVSQEPVLFGCSIAENIAYGDVSRAVSRDEVVAAARAANLHDFVESLPQAYDTVVGERGAQLSGGQKQRVAIARALLRDPRVLLLDEATSALDAESEKVVQDALEK--AQQGRTCIVIAHRLSTVRAAD 449
BLAST of SMED30003432 vs. Ensembl Sea Lamprey
Match: abcb9 (ATP-binding cassette, sub-family B (MDR/TAP), member 9 [Source:ZFIN;Acc:ZDB-GENE-050517-12]) HSP 1 Score: 270.781 bits (691), Expect = 3.135e-81 Identity = 157/486 (32.30%), Postives = 265/486 (54.53%), Query Frame = -1 Query: 1 SVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVG-SLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVI-PESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1452 +++ ++++ + I+ ++ +LT +R + R+R+ F +L+ QE+ +FD +TG + ++L D + +S F++ + G I F W+LS + + +PI+ F +K S + ++A G AEE L++IRTV + + +E E +RY L+ ++++ S T + ++YY G L + + + I + +G+ L N + + A AA +F+ ++R P++ + G + P G + FK+V F YP+RP P+L+ +F L G A +GPSGSGKS+ +HLLQR Y+PL G + G + + + + +V QEP LF+ S+++NI G D ++ ++Q +NA+EFI + T G++GA SGGQKQR+AIA ALVR+P++L+LDEATSALD SE +VQ+ L G RTV+++AHRL +V AD Sbjct: 252 AILYMSLIAIASSIAAGLRGGLFTLTMSRLNIRIRNLLFRSLIHQEVAFFDTTRTGDITSRLNSDTTVVSDVVSQNANVFLRSLVKAGGVCIFMFGLSWRLSLLTLLGLPIVTLVSKFYGDFYEKLSKAVQDSLAVASGAAEETLAAIRTVRSLAGEEAECRRYRDALQHTYRHNRRQALAYAGFSCSNSLTQLALQVGILYYGGHLVVTDRISGAHLISFILYQMELGA-CLENMGSVYTGLMQAVGAAGKVFEYMEREPRM--RTDGTLAPVQLEGQVSFKDVTFAYPSRPDAPVLKGVSFELQPGLVTALVGPSGSGKSSCVHLLQRLYEPLGGRVLLDGQSVHKYQHHYLHTKVALVGQEPVLFARSLRDNIAYGMEDCPENAVISASQQANAHEFISDLPLAYQTEAGEKGAQLSGGQKQRVAIARALVRDPRVLILDEATSALDAESEHMVQQALYNGELRG-RTVLVIAHRLSSVERAD 733
BLAST of SMED30003432 vs. Ensembl Yeast
Match: MDL1 (Mitochondrial inner membrane half-type ABC transporter; mediates export of peptides generated upon proteolysis of mitochondrial proteins; plays a role in the regulation of cellular resistance to oxidative stress [Source:SGD;Acc:S000004178]) HSP 1 Score: 242.662 bits (618), Expect = 7.190e-72 Identity = 161/478 (33.68%), Postives = 255/478 (53.35%), Query Frame = -1 Query: 4 QMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDV----ESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAG--GIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGD-IEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENI------QLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNA 1398 +++ + +T R RLR+ A L Q+ + D + G L+++L+ D +S+ +SD A IQ FVG +++F + WKL+ + + P + + I+ S +Q++ S+ G +AEE L++ RT+ A+ ++ EV+RY+ ++ +G+K ++ GL G G T + +G I GS G + + V +L + AA +F++ DR P I G P S I FKNV F YPTRP I ++ N T+ G+ V +GPSGSGKSTI LL R+YD +G I F D+++ +L YR IG VQQEP LF+G+I +NI ++ + D + I ++ +N +F+ T +G RGA SGGQKQRIA+A A + +P +L+LDEATSALD+ SE++V K L + + G T + +AHRL T++++ Sbjct: 173 RIIILKVTGERLVARLRTRTMKAALDQDATFLDTNRVGDLISRLSSDASIVAKSVTQNVSDGTRAIIQ---GFVGFGMMSFLS-WKLTCVMMILAPPLGAMALIYGRKIRNLS-RQLQT-SVGGLTKVAEEQLNATRTIQAYGGEKNEVRRYAKEVRNVFHIGLKEAVTSGLFFGSTGLVGNTAMLSLLLVGTSMIQSGSMTVGELSSFMMYAVYTGSSLFGLSSFYSELMKGAGAAARVFELNDRKPLI-RPTIGKDPVSLAQKPIVFKNVSFTYPTRPKHQIFKDLNITIKPGEHVCAVGPSGSGKSTIASLLLRYYDVNSGSIEFGDEDIRNFNLRKYRRLIGYVQQEPLLFNGTILDNILYCIPPEIAEQD---DRIRRAIGKANCTKFLANFPDGLQTMVGARGAQLSGGQKQRIALARAFLLDPAVLILDEATSALDSQSEEIVAKNLQRRVERG-FTTISIAHRLSTIKHS 639
BLAST of SMED30003432 vs. Ensembl Yeast
Match: MDL2 (Mitochondrial inner membrane half-type ABC transporter; required for respiratory growth at high temperature; localizes to vacuole membrane in response to H2O2; similar to human TAP1 and TAP2 implicated in bare lymphocyte syndrome and Wegener-like granulomatosis [Source:SGD;Acc:S000006191]) HSP 1 Score: 236.884 bits (603), Expect = 4.228e-69 Identity = 165/492 (33.54%), Postives = 252/492 (51.22%), Query Frame = -1 Query: 1 AILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYE-GSYDPGTVIQIFLTI------VIGSIALGNAVPMLENF----ITAKAAAYPLFQVIDRVPQISHK-KHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG-KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1437 A+L C + F + + + + + R RLR+N L Q+ +FD + G L+++L D + ++ K++ ++ + V + + + +LS + P + + S+ I+ S +A +AEE LS I+TV +F A+ E+ RY+ +++ +G + FT SL+ + L + GSY V+Q L+I ++ + GNAV L F + AA LF++ DR P IS H P+ G IEFK+V F YPTRP V I +N NF + G +V +GPSG GKSTI LL R+Y+P G I+ D+ ++ R HIG+VQQEP L SG+I++NI G EEI + + FI K ++T +G G SGGQKQRIAIA AL++ P +L+LDEATSALD SE + T + + T+V +AHRL T+R ++ Sbjct: 177 ALLIGCA--ANFGRFILLRILSERVVARLRANVIKKTLHQDAEFFDNHKVGDLISRLGSDAYVVSRSMTQKVSDGVKALICGVVGVGMMCSLSPQLSILLLFFTPPVLFSASVFGKQIRNTSKDLQEATGQLTRVAEEQLSGIKTVQSFVAEGNELSRYNVAIRDIFQVGKTAAFTNA--------KFFTTTSLLGDLSFLTVLAYGSY---LVLQSQLSIGDLTAFMLYTEYTGNAVFGLSTFYSEIMQGAGAASRLFELTDRKPSISPTVGHKYKPDR--GVIEFKDVSFSYPTRPSVQIFKNLNFKIAPGSSVCIVGPSGRGKSTIALLLLRYYNPTTGTITIDNQDISKLNCKSLRRHIGIVQQEPVLMSGTIRDNITYGLTYTPTKEEIRSVAKQCFCHNFITKFPNTYDTVIGPHGTLLSGGQKQRIAIARALIKKPTILILDEATSALDVESEGAINYTFGQLMKSKSMTIVSIAHRLSTIRRSE 653
BLAST of SMED30003432 vs. Ensembl Yeast
Match: ATM1 (Mitochondrial inner membrane ATP-binding cassette (ABC) transporter; exports mitochondrially synthesized precursors of iron-sulfur (Fe/S) clusters to the cytosol; human homolog ABCB7 can complement yeast null mutant [Source:SGD;Acc:S000004916]) HSP 1 Score: 204.142 bits (518), Expect = 8.555e-58 Identity = 145/457 (31.73%), Postives = 237/457 (51.86%), Query Frame = -1 Query: 1 FNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQIS--SF---VGCIILAFTTGWKLSFIGSMSIPIMATTFSL-----MIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGV-IPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1338 F L++ ++ W +QTG LT ++ GIS L A + I SF V C IL + G + I + S ++ + F++ HF + + KA + A +A + L + V F+ ++ +Y+ +L +K S + T + + YMG + G+ G ++ I + S+ L + + + LF++ +I + + + +PE+ DI F+NV F Y P IL+N +FT+P G A +G SGSGKSTI+ L+ RFYDP +G I +G D+K+ D+ R IGVV Q+ PLF+ +I EN++ G++DA +EE++ + + I K Q F+T +G+RG SGG+KQR+AIA L++N +++ DEATSALD +E+ + +T+ G RT V +AHRL+T+ +AD Sbjct: 195 FQHLMKLDLGWHLSRQTG----GLTRAMDRGTKGISQVLTAMVFHIIPISFEISVVCGILTYQFGASFAAI-TFSTMLLYSIFTIKTTAWRTHFRRDAN----KADNKAASVALDSLINFEAVKYFNNEKYLADKYNGSLMNYRDSQIKVSQSLAFLNSGQNLIFTTALTAMMYMGCTGVIGGNLTVGDLVLINQLVFQLSVPLNFLGSVYRDLKQSLIDMETLFKLRKNEVKIKNAERPLMLPENVPYDITFENVTFGY--HPDRKILKNASFTIPAGWKTAIVGSSGSGKSTILKLVFRFYDPESGRILINGRDIKEYDIDALRKVIGVVPQDTPLFNDTIWENVKFGRIDATDEEVITVVEKAQLAPLIKKLPQGFDTIVGERGLMISGGEKQRLAIARVLLKNARIMFFDEATSALDTHTEQALLRTIRDNFTSGSRTSVYIAHRLRTIADAD 640
BLAST of SMED30003432 vs. Ensembl Yeast
Match: STE6 (Plasma membrane ATP-binding cassette (ABC) transporter; required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells; human homolog ABCB1 mediates multidrug resistance in many chemotherapy-resistant tumors by effluxing toxic compounds from the cell [Source:SGD;Acc:S000001692]) HSP 1 Score: 181.8 bits (460), Expect = 7.387e-49 Identity = 119/466 (25.54%), Postives = 236/466 (50.64%), Query Frame = -1 Query: 1 LRSNYFNALLRQEICWF--DKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLK-EAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDR------VPQISHKKHGVIPESFYGD-----IEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINE-EIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1353 LR+ L R+ + WF + + ++ + +D+ + S +S+ L+A ++ +I A +GWKLS + P++ ++ ++K + + +I+++I+T+ A E + H+LK + + + KR+I G G + + + +++YY GL + Y + F ++ ++ + V + + + AA +++++D V + + G+ +++G + +N+ F YP+ P + +N NF + G+T+ IG SG+GKST++ LL + Y+ G+I GTD+ D +LT R I VV+Q+P LF+G+I++N+ G D I E E+ + + ++F++ + Q +T + SGGQ QR+ IA AL+R ++L+LDE TSALD++S ++ + + K +++ H Q +R+ + Sbjct: 795 LRNEVMEKLTRKNMDWFSGENNKASEISALVLNDLRDLRSLVSEFLSAMTSFVTVSTIGLIWALVSGWKLSLVCISMFPLIIIFSAIYGGILQKCETDYKTSVAQLENCLYQIVTNIKTIKCLQA-EFHFQLTYHDLKIKMQQIASKRAIATGFGISMTNMIVMCIQAIIYYYGLKLVMIHEYTSKEMFTTFTLLLFTIMSCTSLVSQIPDISRGQRAASWIYRILDEKHNTLEVENNNARTVGIAGHTYHGKEKKPIVSIQNLTFAYPSAPTAFVYKNMNFDMFCGQTLGIIGESGTGKSTLVLLLTKLYNCEVGKIKIDGTDVNDWNLTSLRKEISVVEQKPLLFNGTIRDNLTYGLQDEILEIEMYDALKYVGIHDFVISSPQGLDTRIDT--TLLSGGQAQRLCIARALLRKSKILILDECTSALDSVSSSIINEIVKK--GPPALLTMVITHSEQMMRSCN 1255 HSP 2 Score: 177.563 bits (449), Expect = 1.788e-47 Identity = 134/476 (28.15%), Postives = 222/476 (46.64%), Query Frame = -1 Query: 1 RQSRRLRSNYFNALLRQE-ICWFDKQQT--GQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIM---ATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVID----RVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAI---------NEEIVK-STQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1368 RQ R+RS A L ++ + W+D + G T++ VE + S ++ A Q + + + +F W L+ I S PI+ A FS MIH YS K+ S A + +++ + V + Q E K++ + T +K +G++ F T+ ++ G I +G + VI F + ++ L N + + A + ++ R P H + D+ F NV F YP+RP +L+N + G+ +G SGSGKST+ +LL RFYD G IS +G +++ ID +I VV+Q LF+ ++++NI LG D++ N ++K + Q + FI+ T +G G SGGQ+QR+AIA A +R+ +L LDEA SALD + L+ K + + +GK T+++ H L + + D Sbjct: 102 RQGFRIRSQILEAYLEEKPMEWYDNNEKLLGDF-TQINRCVEELRSSSAEASAITFQNLVAICALLGTSFYYSWSLTLIILCSSPIITFFAVVFSRMIHV---YSEKENSETSKAAQLLTWSMNAAQLVRLYCTQRLERKKFKEIILNCNTFFIKSCFFVAANAGILRFLTLTMFVQGFWFGSAMIKKGKLNINDVITCFHSCIMLGSTLNNTLHQIVVLQKGGVAMEKIMTLLKDGSKRNPLNKTVAHQFPLDYATSDLTFANVSFSYPSRPSEAVLKNVSLNFSAGQFTFIVGKSGSGKSTLSNLLLRFYDGYNGSISINGHNIQTIDQKLLIENITVVEQRCTLFNDTLRKNILLGSTDSVRNADCSTNENRHLIKDACQMALLDRFILDLPDGLETLIGTGGVTLSGGQQQRVAIARAFIRDTPILFLDEAVSALDIVHRNLLMKAI-RHWRKGKTTIIL-THELSQIESDD 571
BLAST of SMED30003432 vs. Ensembl Yeast
Match: YOR1 (Plasma membrane ATP-binding cassette (ABC) transporter; multidrug transporter mediates export of many different organic anions including oligomycin; homolog of human cystic fibrosis transmembrane receptor (CFTR) [Source:SGD;Acc:S000003513]) HSP 1 Score: 135.961 bits (341), Expect = 1.051e-33 Identity = 131/521 (25.14%), Postives = 238/521 (45.68%), Query Frame = -1 Query: 1 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVG-CIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKK--YSIKQIKAY--SIAGGIAEEILSSIRTVVAFSAQEKEVKRYS---HNLKEAETLGV--KRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGN----AVPMLENFITAKAAAYPLFQVIDRVP-QISHKKHGVIPESFY---GDIEFKNVDFEYPTRPGVPI-LQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINE----------------------EIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1440 F + ++ F++G Q + S+ L +L + + D G+++ + T D +S+++ +++ L Q ++ VG C++ W +++IP + F L+ + IK+++A S E+L + T+ A+ +QE+ + + + + EA L V +R + L I F + + LL + + + LT V+ L N A+ EN + + A L +P + S++K + P + G+I F+NVDF Y RPG+PI L+N N + G+ + G +G+GKSTI+ L R + AG+I D+ + L R + ++ Q+P LF G+I++N +D NE E+ D N M K + + + G+ FS G++Q +A+ ALVR ++L+LDEATS++D ++ +Q + + G T++ +AHRL+T+ N D Sbjct: 940 FFVFAAFIFMNG--QFTILCAMGIMASKWLNLRAVKRILHTPMSYIDTTPLGRILNRFTKDTDSLDNELTESLRLMTSQFANIVGVCVMCIVYLPW-----FAIAIPFLLVIFVLIADHYQSSGREIKRLEAVQRSFVYNNLNEVLGGMDTIKAYRSQERFLAKSDFLINKMNEAGYLVVVLQRWVGIFLDMVAIAFALI--------ITLLCVTRAFPISAASVGVLLTYVLQLPGLLNTILRAMTQTENDMNS---AERLVTYATELPLEASYRKPEMTPPESWPSMGEIIFENVDFAY--RPGLPIVLKNLNLNIKSGEKIGICGRTGAGKSTIMSALYRLNELTAGKILIDNVDISQLGLFDLRRKLAIIPQDPVLFRGTIRKN-----LDPFNERTDDELWDALVRGGAIAKDDLPEVKLQKPDENGTHGKMH-KFHLDQAVEEEGSNFSLGERQLLALTRALVRQSKILILDEATSSVDYETDGKIQTRIVEEF--GDCTILCIAHRLKTIVNYD 1432 HSP 2 Score: 54.6842 bits (130), Expect = 4.029e-8 Identity = 43/190 (22.63%), Postives = 90/190 (47.37%), Query Frame = -1 Query: 4 QNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGK--MDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDN-ISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNA 564 ++ NF + G+ + GP G+GKS++++ + G++ +G D+ + Y P + + S+++NI G +E+V+ + + T +G+RG SGGQK RI +A ++ + + L D+ SA+D+ + + ++ + L +A +T ++ H+L + A Sbjct: 605 KDLNFDIKKGEFIMITGPIGTGKSSLLNAMAGSMRKTDGKVEVNG----DLLMCGY----------PWIQNASVRDNIIFGSPFNKEKYDEVVRVCSLKADLDILPAGDM---TEIGERGITLSGGQKARINLARSVYKKKDIYLFDDVLSAVDSRVGKHIMDECLTGMLA--NKTRILATHQLSLIERA 775
BLAST of SMED30003432 vs. Ensembl Nematostella
Match: EDO49737 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFK3]) HSP 1 Score: 428.713 bits (1101), Expect = 7.799e-138 Identity = 210/487 (43.12%), Postives = 313/487 (64.27%), Query Frame = -1 Query: 4 MRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNA 1461 M I + L+ I ++Q TA RQ++R+R N+F A++RQ+I WFD G+L +LT+D+ + G+ K+ +Q ++F+ I+ F WKL+ + P+M +M I ++ K+++AY+ AG IAEE+LSSIRTV AF ++KE +RY+ +L EA+ GVK+ + GLG G +F SL ++ G + + + + + G ++ +F ++++G+ LG A P +E TA+ AAY L+ +IDR P I S + G+ P S GDI+F ++ F+YP+RP V +L+ + T+ G+TVA +G SG GKST+I L+QRFYDP G + G D++ ++L W R HIGVV QEP LF+ ++ ENI+ G+ EI K+T+ +NA++FI Q +NT +G+RGA SGGQKQRIAIA ALV+NP LL+LDEATSALD SEK+VQ LDK +EG RT +++AHRL T+RNA Sbjct: 1 MTDLAIYYIYLAIGALIVAYLQAGFFQYTAVRQAKRIRCNFFKAVMRQDIGWFDTYDAGELNNRLTEDISKVVDGLGSKVGLVVQFTTTFLAGFIMGFAYSWKLTLVILALTPLMVIAGGIMGKVISVFTSKELEAYAKAGAIAEEVLSSIRTVAAFGGEKKECERYNSHLGEAQAFGVKKGLSTGLGFGFFQLIMFGSYSLAFWYGAVLVADKAINSGDLLVVFFSVMVGATQLGQAGPNIEAIATARGAAYELYSIIDRQPPIDSSSEEGLKPASVKGDIDFTDIHFQYPSRPDVKVLKGLHLTIRSGQTVALVGESGCGKSTLIKLVQRFYDPAEGTVCMDGIDIRSLNLKWLRQHIGVVSQEPILFATTVAENIRYGREGITQAEIEKATKMANAHDFIRNLPQGYNTVVGERGAQMSGGQKQRIAIARALVKNPTLLILDEATSALDTESEKIVQAALDKA-SEG-RTTLVIAHRLSTIRNA 485 HSP 2 Score: 307.76 bits (787), Expect = 1.438e-92 Identity = 173/488 (35.45%), Postives = 269/488 (55.12%), Query Frame = -1 Query: 1 IKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDK--QQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSL-MIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1446 + F ++ +F + Q +++ + ++R F +LLRQE+ +FD TG L T L ++ +L +S+ V I AF GWKLS + IP + +L M F + K Y +G IA E ++RT+ + + YS ++ + V+R+ G G+ +F + + G I +G D V+++ + IVI + G + ++ A+ AA +F+++DR P I S ++G+ P + G ++ ++V F+YPTRP V +L+ + + G+T+A +GPSG GKST + LL+RFYDP GE++ +++ ++L W RS IG+V QEP LF SI +NI G + EI + + +N + FI + ++T +GD+G SGGQKQRIAIA AL+RNP +LLLDEATSALD SEK+VQ LD +EG RTV+M+AHRL TV+NAD Sbjct: 595 LMFLVMGGASFFTQIFQNYMFAISGEALTVKIRRLSFKSLLRQEMAFFDDPFHTTGALTTALATHASDVKGAAGSRLGTLALGLSTVVASAIYAFYNGWKLSLVVCAFIPFIVLAGALHMKAFTGDHGGKD--DYIESGKIAVEAFENVRTIATLGREHTFFEHYSRSIDGPHKVAVRRAHLSGASYGLTEAIMFLCNAACFRFGAYLIVQGEMDMPRVMKVVMCIVIAGLVAGQISSLSPDYQKARTAAGKIFKLLDRTPAIDSASENGLQPAAVRGTVQVRSVRFKYPTRPNVKVLRGLSLEVNQGQTLALVGPSGCGKSTTVSLLERFYDPEDGEMAIDNANVRQLNLKWLRSKIGIVSQEPVLFGYSIAQNIAYGDNSREVSMAEIETAAKAANIHNFICGLPKGYDTEVGDKGTLISGGQKQRIAIARALIRNPPILLLDEATSALDTESEKVVQDALDAA-SEG-RTVIMIAHRLSTVKNAD 1078
BLAST of SMED30003432 vs. Ensembl Nematostella
Match: EDO41930 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S348]) HSP 1 Score: 308.145 bits (788), Expect = 1.231e-94 Identity = 174/489 (35.58%), Postives = 278/489 (56.85%), Query Frame = -1 Query: 1 ISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPIL------------------QNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1413 I+ I+ +L R R+R FNA+++QE+ +FD +TG+L+ +L+ D + I++ ++ ++ ++ I +G ++ FT KL+ + IPI+ F++ K A +AEE + SIRTV +FS ++K +K Y+ + E+ +G + +I G SGV+ LV + G + EG + G + L V ++A + +F+ A A++ +F+++DRVP+I + GVI SF I F +V F YP+R +L + +F + G+TVA +GPSG GKST+I L++RFYDP+ G I TD+ +DL WYR I +V QEP LF+ +I NI G+ DA EEI ++ + +NA++FI + + T +G+RG SGGQKQR+AIA AL+ +P++LLLDEATSALD SE V++ +D+ + RTV+++AHRL TVR+A+ Sbjct: 277 IAAMIRAWLFTLAGQRLVARIRRELFNAIIKQEVAFFDTNRTGELINRLSSDTQVIQNAVTVNVSMLLRYIVQIIGSLVFMFTLSAKLTGVLISVIPIVGVGAQKYGQFVQGLRKKFQDELGNASTVAEESIGSIRTVRSFSQEKKTMKLYAEAIHESYLVGARLAIASGAFSGVVMAVGQAAIVLVLWYGGKLVNEGEMNVGILTAFALYTVNVAMAFAFLSSLYGDFMQAVGASFRMFELMDRVPKIKMEG-GVILPSFKEPIVFDDVRFSYPSREDTEVLKIEEAARQANAHDFITTFEALSFKINPGETVALVGPSGGGKSTVISLIERFYDPMTGNIRIGDTDISLLDLAWYRKKIALVSQEPVLFATTIASNIAYGR-DASQEEIEEAARQANAHDFITTFEDGYKTQVGERGVKLSGGQKQRVAIARALLMDPEILLLDEATSALDAESEHFVKEAIDRAMV--NRTVLVIAHRLSTVRSAN 761
BLAST of SMED30003432 vs. Ensembl Nematostella
Match: EDO45926 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRD5]) HSP 1 Score: 292.352 bits (747), Expect = 2.336e-91 Identity = 166/461 (36.01%), Postives = 264/461 (57.27%), Query Frame = -1 Query: 1 TAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMD-AINEEIVKS-TQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1377 A+R + R+ + F +++ Q+I +FDK +TG++V++LT D + +S + F++ + G I F W+LS + + +P++A + ++ KK S A + +A E++SS++TV +F+ ++ E+ RY E L +K ++ G +G + ++ Y G + EG G ++ L + + AL + + A AA +F++IDR P I + VIP S G IEFK+V F YPTRP +P+L N +F + G+ VA +GPSG GKST I+LL+ Y+P GE+ +KD+D + + + +V QEP LF+ SI++NI G D A N E V+ ++ +NA+ F+ + ++T G++G SGGQKQRIAIA AL+RNP++LLLDEATSALD SE LVQ + K + TV+++AHRL T+ AD Sbjct: 78 VASRFNIRINNLLFGSIVNQDISFFDKTKTGEIVSRLTSDTTKMSDQVSLNVNVFLRNVFKGAGVCIFMFKLSWQLSVVTMIGLPLIAFLSEVYGNYYKKLSTAVQDAIARTNEVAAEVVSSMKTVRSFANEQGELNRYKEKNNEVFKLQIKEAVVIGGYNGCTEIMFLAMEVIILYYGGHLVLEGYLTGGNLVSFILYQLELADALEEIGDVYTGLMEAVGAAEKVFKLIDREPAILNNGK-VIPLSCEGAIEFKDVSFSYPTRPDIPVLDNVSFMVEPGQVVALVGPSGGGKSTCINLLEHLYEPTGGEVLIDAVPVKDLDHYYLHNKVSLVGQEPVLFARSIKKNIAYGVEDLADNPETVEHVSRLANAHSFVSGMPKGYDTETGEKGLQLSGGQKQRIAIARALIRNPKILLLDEATSALDAESEHLVQDAIYKNLQ--GHTVLIIAHRLSTIEKAD 535
BLAST of SMED30003432 vs. Ensembl Nematostella
Match: EDO48846 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHG7]) HSP 1 Score: 292.352 bits (747), Expect = 1.428e-88 Identity = 169/487 (34.70%), Postives = 260/487 (53.39%), Query Frame = -1 Query: 1 IKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDK--QQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG--KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1446 + F + +F + Q +L+ + RLR ALLRQEI +FD TG L T L ++ +L IS+ + I A GWKL+ +P +A +L I + Q Y +G +A E ++RT+ ++ +RY+ L V R+ G G GV ++ + + G + E V+++ + I+I + G +++ AK A +F+++DR+P I S G+ P + G ++ +++ F YP RP V +L+ + + G+T+A +GPSG GKST + LL+RFYDP G+++ D++ +++ W RS IG+V QEP LF SI +NI G + +EI + + +N ++FI + + T +GD+G SGGQKQRIAIA ALV+NP +LLLDEATSALD SEK+VQ LD +EG RTV+M+AHRL TV+NAD Sbjct: 326 LMFLAMGGISFFTQLFQNYMFALSGEALTVRLRRMSLKALLRQEIAFFDDPMHSTGALTTALATHTSDVKGAAGSRLGTIATGISTVIASAIYASINGWKLTLAVLAFVPFLAIGRALEIKGYTGDTGGQ-NDYIESGKVAVEAFENVRTIAILGREKTFFERYAQTLVRPHRAAVVRAHLFGAGYGVTEAIMYFCFAACFRYGAHLMVEKEMTMEEVMKVVMCIMIAGMVAGELFAFSPDYLKAKVAGARIFKLVDRIPVIDSASDEGLTPSTVQGTLQMRSLRFRYPARPDVKVLRGLSLEVKQGQTLALVGPSGCGKSTTVSLLERFYDPEEGKVAVDNRDVRQLNIKWLRSKIGIVSQEPVLFGYSIAQNIAYGDNSREVSMKEIETAARAANIHDFISGLPKGYETEVGDKGTLLSGGQKQRIAIARALVKNPPILLLDEATSALDTESEKVVQDALDAA-SEG-RTVIMIAHRLSTVKNAD 809 HSP 2 Score: 182.185 bits (461), Expect = 7.218e-49 Identity = 87/165 (52.73%), Postives = 119/165 (72.12%), Query Frame = -1 Query: 1 STIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 495 ST+I L+QRFYDP G + GTD++ ++L W R IGVV QEP LF+ +I ENI+ G+ EI ++ + +NA++FI K + + T +G++G+ SGGQKQR+AIA ALVRNP++L+LDEATSALD SE++VQ LDK A RT +++AHRL TVRNAD Sbjct: 1 STVIKLIQRFYDPENGSVCLDGTDIRSLNLHWLRQRIGVVSQEPALFATTIAENIRYGQDGVTQAEIEQAAKMANAHDFITKLPKGYETVVGEQGSQLSGGQKQRVAIARALVRNPRILILDEATSALDTESERVVQAALDK--AREGRTTLVIAHRLSTVRNAD 163
BLAST of SMED30003432 vs. Ensembl Nematostella
Match: EDO39130 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAY5]) HSP 1 Score: 257.299 bits (656), Expect = 8.587e-77 Identity = 155/478 (32.43%), Postives = 260/478 (54.39%), Query Frame = -1 Query: 1 SGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIP--ESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG------KMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1410 + F ++ I ++ R ++LR N F+++LRQE +FD+ +TG+LV +L+ D + ++D ++ ++ ++ + + KL+ I + +P +A + F++ + + + + A +AEE +S+I V AF + +E+K Y+ ++ L + ++ + + G G + + V Y G + + G + L +++ + A+ ++Q+ DR P +S G+ P + I+FKNV+F YP+RP I + + + G A +GPSGSGKST+ LL R YDP +G + G D+K + L W R +G V Q+P LFS SI ENI G MDAI + + + +NA FI ++T +G+RG SGGQ+QRIAIA A+++NP++LLLDEATSALD+ SE LVQ+ L++ + RTV+ +AHRL T++NAD Sbjct: 189 ANFGRVYLIQVSGQRIVKQLRQNLFSSILRQETAFFDRTKTGELVNRLSADTILVGKAVTDNVSDGLRAVAQVTAGVSMMAYVSPKLTGIVLLIVPPVAVGAVVYGRFLRSITKRTQDSLADATQVAEERISNIHVVRAFGQENREIKSYTDRVEYVLQLAKREALARAVFFGFTGLSGNLIVLSVLYSGGMMMTSAQISVGELTSFMLYTGFVGVSIAGLSSFYSELMKGIGASSRVWQLSDRKPAMSFT-GGLQPSIDVLARGIQFKNVNFTYPSRPNARIFADLSLDMRAGSVTAVVGPSGSGKSTLGALLLRLYDPESGSVFVGGHDVKSLSLDWLRGAVGAVHQDPILFSCSIAENIAYGAASSEVSMDAIKD----AARQANAANFIESFPNGYDTIVGERGQMLSGGQRQRIAIARAILKNPKILLLDEATSALDSESEHLVQEALERLMK--GRTVITIAHRLSTIKNAD 659
BLAST of SMED30003432 vs. Ensembl Medaka
Match: abcb4 (ATP binding cassette subfamily B member 1 [Source:NCBI gene;Acc:101171435]) HSP 1 Score: 452.21 bits (1162), Expect = 6.113e-152 Identity = 231/555 (41.62%), Postives = 355/555 (63.96%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVS-------PRDLTMTFSERMRPS-VIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 VS +FRFA G D+L++++ + +I GA PL ++F D+ + L++ ++ T F PS + ++I+ + ++ ++Q+ ++ A RQ +R+R+ +F+ +++Q+I WFD +TG+L T+LTDDV I+ GI DK+ IQ +SSF+ ++ FT GWKL+ + P + + +L + ++ K+ AY+ AG +AEE+LSSIRTV AFS Q KE++RY NL++A+ +G+K++I + G I+ +L ++ G I G Y G+V+ +F ++IG +G P ++ F +A+ AA+ ++ +ID+ P I S+ + G P+ GDIEF N+ F YP+RP V IL+N + ++ G+T+A +G SG GKST I LLQRFYDP+ G +S G D++ +++ + R IGVV QEP LF+ +I ENI+ G+ D EI ++ +++NAY+FIM KF T +GDRG SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK RT ++VAHRL T+RNAD Sbjct: 29 VSPIAVFRFADGWDILMLVIGTVMAIANGAVLPLMCIVFGDMTDSLINGMKGCFRAKNATSLF-----PSFAVYYSIMGAVVLVAAYLQVSLWTIAAGRQVKRIRTLFFHKIMQQDIGWFDINETGELNTRLTDDVYKIQEGIGDKVGMLIQSVSSFITAFVIGFTKGWKLTLVILAVSPALGISGALFSKVLTSFTSKEQSAYAKAGAVAEEVLSSIRTVFAFSGQNKEIERYHKNLQQAKKMGMKKAISANIAMGFTFLMIYFSYALAFWYGSTLILSGEYTIGSVLTVFFVVIIGVFTMGQTSPNIQTFASARGAAHKVYNIIDKEPIIDSYSEDGFKPDFIKGDIEFSNIHFTYPSRPDVKILENMSLSVKSGQTMALVGSSGCGKSTTIQLLQRFYDPVEGNVSIDGHDIRSLNVRYLREMIGVVSQEPILFATTISENIRYGRPDVTQPEIEQAAKEANAYDFIMNLPNKFETLVGDRGTQMSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQSALDKV--RLGRTTLIVAHRLSTIRNAD 576
BLAST of SMED30003432 vs. Ensembl Medaka
Match: abcb4 (ATP binding cassette subfamily B member 1 [Source:NCBI gene;Acc:101171435]) HSP 1 Score: 455.292 bits (1170), Expect = 4.218e-146 Identity = 233/561 (41.53%), Postives = 358/561 (63.81%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLV--SPRDLT-----MTF-------SERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQI-SHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 VS +FRFA G D+L++++ + +I GA PL ++F D+ + L+ +P ++T +TF E M + ++I+ + ++ ++Q+ ++ A RQ +R+R+ +F+ +++Q+I WFD +TG+L T+LTDDV I+ GI DK+ IQ +SSF+ ++ FT GWKL+ + P + + +L + ++ K+ AY+ AG +AEE+LSSIRTV AFS Q KE++RY NL++A+ +G+K++I + G I+ +L ++ G I G Y G+V+ +F ++IG +G P ++ F +A+ AA+ ++ +ID+ P I S+ + G P+ GDIEF N+ F YP+RP V IL+N + ++ G+T+A +G SG GKST I LLQRFYDP+ G +S G D++ +++ + R IGVV QEP LF+ +I ENI+ G+ D EI ++ +++NAY+FIM KF T +GDRG SGGQKQRIAIA ALVRNP++LLLDEATSALD SE +VQ LDK RT ++VAHRL T+RNAD Sbjct: 41 VSPIAVFRFADGWDILMLVIGTVMAIANGAVLPLMCIVFGDMTDSLINGAPPNMTAGYPNLTFINMTIDIEEEMTVFAVYYSIMGAVVLVAAYLQVSLWTIAAGRQVKRIRTLFFHKIMQQDIGWFDINETGELNTRLTDDVYKIQEGIGDKVGMLIQSVSSFITAFVIGFTKGWKLTLVILAVSPALGISGALFSKVLTSFTSKEQSAYAKAGAVAEEVLSSIRTVFAFSGQNKEIERYHKNLQQAKKMGMKKAISANIAMGFTFLMIYFSYALAFWYGSTLILSGEYTIGSVLTVFFVVIIGVFTMGQTSPNIQTFASARGAAHKVYNIIDKEPIIDSYSEDGFKPDFIKGDIEFSNIHFTYPSRPDVKILENMSLSVKSGQTMALVGSSGCGKSTTIQLLQRFYDPVEGNVSIDGHDIRSLNVRYLREMIGVVSQEPILFATTISENIRYGRPDVTQPEIEQAAKEANAYDFIMNLPNKFETLVGDRGTQMSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQSALDKV--RLGRTTLIVAHRLSTIRNAD 599 HSP 2 Score: 323.553 bits (828), Expect = 3.807e-97 Identity = 189/534 (35.39%), Postives = 287/534 (53.75%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFD--KQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYY-------MGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISH-KKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIV------KSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G P+ ++F ++ + P + ER + + F + +F++ F+Q + + +LR F A+LRQ++ WFD K G L T+L D ++ +LA Q ++ IILAF GW+L+ + +PI+A ++ + + ++ + K AG IA E + +IRTV + + + K Y NLK K++ G FT S++Y+ G I +G D V + ++ G++A+G A N+ AK +A L +I++VP I + G P+ F G++ FK+V F YP+RP VPIL+ N + G+T+A +G SG GKST I LL+RFYD G++ D+K +++ W RS IG+V QEP LF ++ ENI G N V + + +N ++FI + Q++NT GD+G SGGQKQRIAIA A++RNPQ+LLLDEATSALD SEK+VQ LD+ A RT ++VAHRL T+RNAD Sbjct: 729 GGIQPVFAVLFSKIIAVFAEPDQEVV--RERSQFFSLMFVTIGCVSFVTMFLQGFCFGKSGEVLTLKLRLGAFKAMLRQDLGWFDDSKNSVGALTTRLATDAAQVQGATGARLATVAQNFANLGTGIILAFIYGWELTLLVLAVVPIIAVAGAVGMQMLTGHAAEDKKELEKAGKIATEAIENIRTVASLTREAKFESLYQENLKVPYKNSQKKAHTHG-------FTFSFSQSMIYFAYAGCFRFGAWLIVQGRMDVEGVFLVISAVLFGAMAVGEANSFAPNYAKAKMSAAHLMMLINKVPDIDNLSNEGETPDKFNGNVIFKDVRFNYPSRPDVPILKGLNLKVKKGETLALVGSSGCGKSTTIQLLERFYDTKEGKVVLDDVDIKQLNIHWLRSQIGIVSQEPVLFDCTLAENIAYGD----NSRTVTMEEIEAAAKAANIHKFIEELPQRYNTQAGDKGTQLSGGQKQRIAIARAILRNPQVLLLDEATSALDTESEKVVQDALDQ--ASKGRTCIIVAHRLSTIRNAD 1247
BLAST of SMED30003432 vs. Ensembl Medaka
Match: abcb11a (ATP binding cassette subfamily B member 11 [Source:NCBI gene;Acc:101157171]) HSP 1 Score: 404.831 bits (1039), Expect = 5.592e-127 Identity = 234/583 (40.14%), Postives = 351/583 (60.21%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLV------------------------------SPRDLTMTFSERMRPSVIKFA-----ILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMG-LLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISH-KKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V Y+QL+RFATG D ++++V ++ GAA PL +L++ + + V + + T+T + + +FA I S +S F M +S AARQ++R+R YF +++ EI WFD G+L T+++DD+ I + I+D+++ FI++IS+F+ ++ F GWKL+ + P++ LM + + + +++KAY+ AG +A+E+LSSIRTV AF +EKE +RY NL EA+ GVK+ G+ G + IF +L ++ G L I PG +IQ+F ++I + LG A P LE F + +AAA +F+ IDR P+I + G + GDIEF NV F YP+RP + IL + N + G+T AF+GPSGSGK++ + L+QRFYDP G ++ G DL+ +++ W RS IG+V+QEP LF+ +I ENI+ G+ E+I+++T+++NAY FIM QKF+T +G+ G SGGQKQRIAIA ALVR P++LLLD ATSALDN SE VQ+ L+K E RT + VAHRL T+R+AD Sbjct: 28 VGYFQLYRFATGRDTVMMVVGGFCALIHGAATPLMLLVYGMMTDTFVAYELEVQELKDPNKECLNDTIYWINGSIYETTDNQTVTCGVNIEGQMTQFAYYYIGIGSGVLLVSYFQIMFWVS-AAARQTQRIRKTYFRRVMQMEIGWFDCNSVGELNTRISDDINKISNAIADQVSIFIERISTFIFGFMVGFIGGWKLTLVVVAVSPLIGMGAGLMAMAVARLTGRELKAYAKAGAVADEVLSSIRTVAAFGGEEKEAERYDRNLVEAQNWGVKKGSIIGVFQGYLWCIIFLCYALAFWYGSKLVIDSKELSPGNLIQVFFGVLIAATNLGQAAPCLEAFASGRAAAKTVFETIDREPEIDCLSEDGYKLDKIKGDIEFHNVTFYYPSRPDIKILDDLNLHIKAGETTAFVGPSGSGKTSAVQLIQRFYDPKEGMVTLDGHDLRSLNIQWLRSLIGIVEQEPVLFATTIAENIRYGRPGVTMEDIIQATREANAYHFIMDLPQKFDTLVGEGGGQMSGGQKQRIAIARALVRKPRILLLDMATSALDNESEATVQEALNKVHTE--RTTISVAHRLSTIRSAD 607 HSP 2 Score: 293.123 bits (749), Expect = 3.682e-86 Identity = 183/522 (35.06%), Postives = 285/522 (54.60%), Query Frame = -1 Query: 1 GAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQT--GQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLG-KMDAIN-EEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 G+ P+ ++F ++ P DL ++ + F +++ +F S FIQ + + + +RRLR F A+L+QEI WFD + G L T+L D ++ ++ I ++S I+AF WKL+ + +P++ + + ++ + KA AG ++ E L +IRTV + + V+ + L+ KR+ GL G+ IF + + G + V ++ +VI ALG A ++ AK AA F+++DRVP+ISH G E+F G++EF N F YPTRP +L+ ++ G+T+A +G SG GKST + LL+RFYDP G++ G + + + RS IG+V QEP LF SI ENIQ G IN EEIV++ + +N ++F+M K++T +G +G+ S GQKQRIAIA A++RNP++LLLDEATSALD SE++VQ LD+ A RT +++AHRL T++NAD Sbjct: 753 GSVNPIYAVLFSQILGTFSIP-DLDEQ-RRQINGICLLFCVVAVISFFSQFIQGFSFAKSGELLTRRLRKVGFQAMLKQEIGWFDDPENSPGALTTRLATDASMVQGATGSQIGMIINSLTSIGASFIIAFYFSWKLTLVILGFLPLIGLSGVFQAKMLTGFAKEDKKAMEAAGRVSSEALGNIRTVAGLTKERSFVESFEEKLELPYKSAKKRANIYGLCFGLTQCVIFMAYAASFRFGGYLVRAEGLQYMLVFRVISAVVISGTALGRASSFTPDYAKAKTAAAQFFKLLDRVPKISHTD-GEKWENFKGEVEFLNCKFTYPTRPDTQVLKGLVVSVKPGQTLALVGSSGCGKSTGVQLLERFYDPDEGKVLIDGRPSYSVSVPFLRSQIGIVSQEPVLFDCSIAENIQYGDNSHRINMEEIVEAAKTANLHDFVMTLPDKYDTQVGAQGSQLSRGQKQRIAIARAIIRNPKILLLDEATSALDTESEQIVQSALDE--ARKGRTCIVIAHRLSTIQNAD 1269
BLAST of SMED30003432 vs. Ensembl Medaka
Match: abcb11b (bile salt export pump [Source:NCBI gene;Acc:101163554]) HSP 1 Score: 398.282 bits (1022), Expect = 3.846e-124 Identity = 233/604 (38.58%), Postives = 354/604 (58.61%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIF---------------------RDVVNLLVSPR-------DLTM----TFSERMRPSVIKFAILS--SC----------------------TFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMG-LLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISH-KKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V ++QLFRFAT D+L++++ + ++ G+A PL +L+F ++ VN + + D+T+ +F + ++ F LS SC F+ G+ Q+ AARQ + +R YF ++R EI WFD G+L T+L+DD+ I I+D+++ F+Q+ ++FV + F GWKL+ + + P++ LM F+ K + +++AY+ AG +A+E+LSSIRTV AF + KEV+RY NL A+ G+++ + G +G + IF +L ++ G L + Y PGT++Q+F +++ +++LG A P LE F + AA +F+ IDR PQI + G E GDIEF NV F YP+RP V IL + + G+T AF+GPSG+GKST I L+QRFYDPL G ++ G D++ +++ W RS IG+V+QEP LF+ +I ENI+ G+ ++I+ + +++NAY FIM QKF+T +G+ G SGGQKQRIAIA ALVRNP++LLLD ATSALDN SE +VQ+ LDK RT + +AHRL T++NAD Sbjct: 55 VGFFQLFRFATCKDVLMMVLGSVCAVLHGSAQPLMLLVFGLLTDTFIDYDIELQELSDDRKECVNNTIQWKRNYTGTLDMTLPLNQSFGSLINSTLEMFTPLSNMSCGILDIEHEMTLFALYYVGIGAGVFLLGYFQISLWVTAAARQIQLIRKLYFTKVMRMEIGWFDCTSVGELNTRLSDDINKINDAIADQVSIFVQRFTTFVCGFCIGFVKGWKLTLVIVAASPLIGIGAGLMALFVAKLTGMELQAYAKAGAVADEVLSSIRTVAAFGGEIKEVERYDRNLVSAQRWGIRKGLIMGFFTGYMWLIIFLCYALAFWYGSTLVVDTAEYTPGTLLQVFFGVLVAAMSLGQASPCLEAFAAGRGAATIIFETIDREPQIDCLSESGYKLERVKGDIEFHNVTFHYPSRPEVKILDQLSVQVKSGETTAFVGPSGAGKSTAIQLIQRFYDPLEGMVTLDGHDIRGLNIQWLRSLIGIVEQEPVLFATTIAENIRYGRPGVSMDDIINAAKEANAYNFIMDLPQKFDTLVGEGGGQMSGGQKQRIAIARALVRNPRILLLDMATSALDNESEAVVQEALDKV--RMGRTTISIAHRLSTIKNAD 656 HSP 2 Score: 280.411 bits (716), Expect = 1.661e-81 Identity = 164/485 (33.81%), Postives = 267/485 (55.05%), Query Frame = -1 Query: 1 FAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQT--GQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQIS-HKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGK--MDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1440 FA++ +F + +Q S + +RRLR F+A+L QEI WFD + G L T+L D ++ ++ + +++ ++++F WKL+ + +P +A + + ++ + +A AG I+ E L++IRT+ ++ V+ Y L +K++ G G +F S Y G + + V ++ IV ALG A ++ AK +A FQ++DR+P IS + G +F G+IEF + F YPTRP + +L ++ G+T+AF+G SG GKST + LL+RFYDP G++ G D K +++ + RS IG+V QEP LF SI ENI+ G + +E++ + + + ++F+ +++NT +G +G+ S GQKQRIAIA A++R+P++LLLDEATSALD SEK VQ+ LDK A RT +++AHRL T++N+D Sbjct: 844 FAMVGVVSFFTQMLQGYAFSKSGELLTRRLRRIGFHAMLGQEIGWFDDHRNSPGALTTRLATDASQVQGATGSQIGMIVNSLTNIGVAVLMSFYFSWKLTLLILCFLPFLALSGGFQAKMLTGFAKQDKQAMETAGRISGEALNNIRTIAGLGKEKNFVEMYEFQLDAPYQAALKKANVYGACYGFAQCVVFMTNSASYRFGGYLVKQEGLHFSLVFRVISAIVTSGTALGRASSYTPDYAKAKISAARFFQLLDRIPTISVYSDKGDKWNNFQGNIEFIDCKFTYPTRPDIQVLNGLTVSVKPGQTLAFVGSSGCGKSTSVQLLERFYDPDHGKVLIDGHDSKHVNVPYLRSKIGIVSQEPILFDCSIAENIKYGDNSREISMDEVILAAKKAQLHDFVTALPEQYNTNVGSQGSQLSRGQKQRIAIARAIIRDPKILLLDEATSALDTESEKTVQEALDK--AREGRTCIVIAHRLSTIQNSD 1326
BLAST of SMED30003432 vs. Ensembl Medaka
Match: abcb8 (ATP binding cassette subfamily B member 8 [Source:NCBI gene;Acc:101174865]) HSP 1 Score: 322.013 bits (824), Expect = 1.095e-100 Identity = 189/530 (35.66%), Postives = 304/530 (57.36%), Query Frame = -1 Query: 1 GAAFPLNV---LIFRDVVNLLVSP-RDLTMTFSERMRPSVIKFAILSSCT--FISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEA----ETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPE-SFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSH-IGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1554 GAA LN+ L+ +VN++ RD T + MR +K + SG+I + +S R + +R F +LLRQ++ +FD +TGQLV +LT D++ +S ++ ++ ++ VGC + + KL+ + + +P + +L+ F++K S + + A G+A+E L ++RTV AF+ +E+E++ Y++ + ++ E LG +I QGL + + +G++ + G I PG ++ + +L + + + ++ +F+ + P I G IP S G ++F N+ F YPTRPG +L+ FN LP KT+A +G SG GKST+ LL+RFYDP +G I G D++ +DL+W R IG + QEP LF SI ENI+ GK +A + E++++++ +NAY FI + FNT +G+RGA SGGQKQRIAIA AL++NP +L+LDEATSALD SE++VQ+ LD+ A RTV+++AHRL T++ AD Sbjct: 146 GAAI-LNIQIPLMLGHLVNVVARHLRDNTGNYIGEMRGPALKLLGMYGIQGLLTSGYI--ILLSRVGERVAADMRKTLFASLLRQDVAFFDANKTGQLVNRLTADIQEFKSSFKLVISQGLRSVTQTVGCFVSLYVISPKLTGLTVVVLPCLVGAGALIGSFLRKLSRLAQEQVAKATGVADEALGNVRTVKAFAMEERELQLYAYEVDKSCEMNENLGNGIAIFQGLSN--VALNCIVLGTI--FAGGTLISNNELSPGDLMSFLVASQTVQRSLASISILFGQMVRGISSGARVFEYLSLQPSIPLCGGGRIPHHSLMGRVDFMNISFSYPTRPGHEVLKKFNLMLPPSKTIAIVGESGGGKSTVAALLERFYDPSSGVIMLDGLDIRTLDLSWLRGQVIGFINQEPVLFGSSIMENIRFGKPEATDAEVIEASKQANAYGFITSFPEGFNTLVGERGATLSGGQKQRIAIARALIKNPSILVLDEATSALDAESERVVQEALDR--ATRGRTVLIIAHRLSTIQRAD 666
BLAST of SMED30003432 vs. Planmine SMEST
Match: SMESG000027392.1 (SMESG000027392.1) HSP 1 Score: 1143.26 bits (2956), Expect = 0.000e+0 Identity = 590/590 (100.00%), Postives = 590/590 (100.00%), Query Frame = -1 Query: 1 MGKTSYNVEEANFANSILKEKPAKSKTDIXXXXXXXXXXXXXXSVSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1770 MGKTSYNVEEANFANSILKEKPAKSKTDIPEAKKEKPKKSAMESVSYYQLFRFATGIDLLIVIVMIISSICVGAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD Sbjct: 1 MGKTSYNVEEANFANSILKEKPAKSKTDIPEAKKEKPKKSAMESVSYYQLFRFATGIDLLIVIVMIISSICVGAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 590 HSP 2 Score: 285.034 bits (728), Expect = 1.787e-83 Identity = 184/541 (34.01%), Postives = 297/541 (54.90%), Query Frame = -1 Query: 1 VGAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMV-------TISLTAARQSRRLRSNYFNALLRQEICWFDKQQT--GQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEIL-----SSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPES-FYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLA------GEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAIN-EEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1557 VGA FP LI+ ++ N+ L TF + M + K L I GFI + + + RLR+ +++L+QE+ +FD+ Q G L +L + ++S +L+ FI+ I + + + F W+LS + + IP +A T I + + + S AG ++ L ++IRTV + S Q+ +Y +LK + + G SG+ ++ V +V+++G +F+ +G D +++++F + + ALG A+ + ++ A+ AA Q IDR+ I K GV+PE G+IEFKN+ F YPTR V +L+ + + G+TVA +G SG GKST+I LL+R+YDP G++ G D+K ++L+W R+ IG+V+QEP LF+ S+ +NI G ++ E ++K + +N ++FI+ + +NT +G RG SGGQKQRI IA AL P +LLLDEATSALD SE +VQ+ LD+ A+ T +++AHRL T++NAD Sbjct: 699 VGAVFPCASLIYAELYNVFA----LKFTFPDLM---ISKGRTLVLLHLIPGFILLFGQLTKAWCLGKAGEALTTRLRTFMMSSVLKQEMAYFDEPQNLPGVLTARLAVEASLVKSAAGIQLSVFIEAIVNLSASLFIGFYYNWELSLLFLIFIPCIALTG------IMQGKLSTGQRLSTAGSVSSSSLVLEVLNNIRTVNSLSLQDHFGDKYFDSLKLDGKKIKSKLVFLGCVSGLAVSALYYVYCVVFFVGAIFLDKGKTDMISLMRVFSCFTMSTAALGRALSLAQDTEKARKAARKTLQTIDRLTAIDAHK-GVVPEEKLTGNIEFKNLHFRYPTRANVSVLRGLDLKINAGQTVALVGHSGCGKSTLIQLLERYYDPWVSKNYGQGQVLLDGHDIKALNLSWVRNQIGLVKQEPSLFNISVADNIIYGSNSDVDYEHMIKVAKMANIHDFILSLPEGYNTVVGQRGGHLSGGQKQRICIARALYNKPPILLLDEATSALDTQSEIVVQEALDR--AQENTTCLVIAHRLSTIKNAD 1223
BLAST of SMED30003432 vs. Planmine SMEST
Match: SMESG000027395.1 (SMESG000027395.1) HSP 1 Score: 764.607 bits (1973), Expect = 0.000e+0 Identity = 369/546 (67.58%), Postives = 455/546 (83.33%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V +++LFRF +D+L++ + +ISSI +G A PLN+LIF+DVVNLLV P + FS +R + FAIL+S I+ F+Q + IS+T RQSRR +SNYF ALLRQEI WFDKQQTGQ++T+ +DD++SIE ISDKLA FIQQ+S F II+A T+GWKL+ +G M+IPIM +HFIKKY I QI+AYS+AGGIAEEILSS+RTVVAF+AQE EV RYS NL +A++LG+K+SI QG+GSG +G ++F++GSLV+Y+GLL I +YDPGTVIQ+FLTIV+GSI++G A P++ENF+TA+AAAY +F+VIDRVP I H+K G+IP++F DI+F+NV F+Y TRPG+ IL NFNFT+PYGKTVAFIGPSGSGKSTIIHLLQRFYDPL+GE+ ++KDIDL WYRSHIGVVQQEPPLFSGSI+ENIQ+GK+DA +EI+KSTQ SNAY+FIM TK+ F+T LGDRG GFSGGQKQRIAIA AL+R+PQLLLLDEATSALDN SEKLVQKTLD TIAEGKRT+VMVAHRLQTVRNAD Sbjct: 50 VPFHRLFRFMNSMDILLISLTVISSIGIGVALPLNMLIFKDVVNLLVLPTG-NINFSSAIRNPINYFAILASGALIASFVQSICISVTGKRQSRRYKSNYFAALLRQEISWFDKQQTGQMITRFSDDIDSIEVAISDKLAQFIQQLSLFFSSIIIAATSGWKLTLVGCMAIPIMIIILYSNLHFIKKYVIAQIRAYSVAGGIAEEILSSVRTVVAFNAQESEVNRYSKNLVKAKSLGIKKSIVQGIGSGCVGLSVFSIGSLVFYVGLLLINSENYDPGTVIQVFLTIVLGSISIGYAAPLIENFMTAQAAAYSIFEVIDRVPSIDHRKLGIIPDTFAKDIKFQNVTFQYSTRPGMTILDNFNFTIPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLSGEVILGDQNVKDIDLNWYRSHIGVVQQEPPLFSGSIRENIQMGKLDATEDEIIKSTQYSNAYDFIMATKETFDTKLGDRGTGFSGGQKQRIAIATALIRDPQLLLLDEATSALDNKSEKLVQKTLDTTIAEGKRTIVMVAHRLQTVRNAD 594
BLAST of SMED30003432 vs. Planmine SMEST
Match: SMESG000027395.1 (SMESG000027395.1) HSP 1 Score: 764.222 bits (1972), Expect = 0.000e+0 Identity = 369/546 (67.58%), Postives = 455/546 (83.33%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V +++LFRF +D+L++ + +ISSI +G A PLN+LIF+DVVNLLV P + FS +R + FAIL+S I+ F+Q + IS+T RQSRR +SNYF ALLRQEI WFDKQQTGQ++T+ +DD++SIE ISDKLA FIQQ+S F II+A T+GWKL+ +G M+IPIM +HFIKKY I QI+AYS+AGGIAEEILSS+RTVVAF+AQE EV RYS NL +A++LG+K+SI QG+GSG +G ++F++GSLV+Y+GLL I +YDPGTVIQ+FLTIV+GSI++G A P++ENF+TA+AAAY +F+VIDRVP I H+K G+IP++F DI+F+NV F+Y TRPG+ IL NFNFT+PYGKTVAFIGPSGSGKSTIIHLLQRFYDPL+GE+ ++KDIDL WYRSHIGVVQQEPPLFSGSI+ENIQ+GK+DA +EI+KSTQ SNAY+FIM TK+ F+T LGDRG GFSGGQKQRIAIA AL+R+PQLLLLDEATSALDN SEKLVQKTLD TIAEGKRT+VMVAHRLQTVRNAD Sbjct: 50 VPFHRLFRFMNSMDILLISLTVISSIGIGVALPLNMLIFKDVVNLLVLPTG-NINFSSAIRNPINYFAILASGALIASFVQSICISVTGKRQSRRYKSNYFAALLRQEISWFDKQQTGQMITRFSDDIDSIEVAISDKLAQFIQQLSLFFSSIIIAATSGWKLTLVGCMAIPIMIIILYSNLHFIKKYVIAQIRAYSVAGGIAEEILSSVRTVVAFNAQESEVNRYSKNLVKAKSLGIKKSIVQGIGSGCVGLSVFSIGSLVFYVGLLLINSENYDPGTVIQVFLTIVLGSISIGYAAPLIENFMTAQAAAYSIFEVIDRVPSIDHRKLGIIPDTFAKDIKFQNVTFQYSTRPGMTILDNFNFTIPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLSGEVILGDQNVKDIDLNWYRSHIGVVQQEPPLFSGSIRENIQMGKLDATEDEIIKSTQYSNAYDFIMATKETFDTKLGDRGTGFSGGQKQRIAIATALIRDPQLLLLDEATSALDNKSEKLVQKTLDTTIAEGKRTIVMVAHRLQTVRNAD 594
BLAST of SMED30003432 vs. Planmine SMEST
Match: SMESG000027395.1 (SMESG000027395.1) HSP 1 Score: 751.125 bits (1938), Expect = 0.000e+0 Identity = 365/546 (66.85%), Postives = 451/546 (82.60%), Query Frame = -1 Query: 1 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEISFSGTDLKDIDLTWYRSHIGVVQQEPPLFSGSIQENIQLGKMDAINEEIVKSTQDSNAYEFIMKTKQKFNTPLGDRGAGFSGGQKQRIAIAMALVRNPQLLLLDEATSALDNISEKLVQKTLDKTIAEGKRTVVMVAHRLQTVRNAD 1638 V +++LFRF +D+L++ + +ISSI +G A PLN+LIF+DVVNLLV P + FS +R + FAIL+S I+ F+Q + IS+T RQSRR +SNYF ALLRQEI WFDKQQTGQ++T+ +DD++SIE ISDKLA FIQQ+S F II+A T+GWKL+ +G M+IPIM +HFIKKY I QI+AYS+AGGIAEEILSS+RTVVAF+AQE EV RYS NL +A++LG+K+SI QG+GSG +G ++F++GSLV+Y+GLL I +YDPGTVIQ+FLTIV+GSI++G A P++ENF+TA+AAAY +F+V P I H+K G+IP++F DI+F+NV F+Y TRPG+ IL NFNFT+PYGKTVAFIGPSGSGKSTIIHLLQRFYDPL+GE+ ++KDIDL WYRSHIGVVQQEPPLFSGSI+ENIQ+GK+DA +EI+KSTQ SNAY+FIM TK+ F+T LGDRG GFSGGQKQRIAIA AL+R+PQLLLLDEATSALDN SEKLVQKTLD TIAEGKRT+VMVAHRLQTVRNAD Sbjct: 50 VPFHRLFRFMNSMDILLISLTVISSIGIGVALPLNMLIFKDVVNLLVLPTG-NINFSSAIRNPINYFAILASGALIASFVQSICISVTGKRQSRRYKSNYFAALLRQEISWFDKQQTGQMITRFSDDIDSIEVAISDKLAQFIQQLSLFFSSIIIAATSGWKLTLVGCMAIPIMIIILYSNLHFIKKYVIAQIRAYSVAGGIAEEILSSVRTVVAFNAQESEVNRYSKNLVKAKSLGIKKSIVQGIGSGCVGLSVFSIGSLVFYVGLLLINSENYDPGTVIQVFLTIVLGSISIGYAAPLIENFMTAQAAAYSIFEV----PSIDHRKLGIIPDTFAKDIKFQNVTFQYSTRPGMTILDNFNFTIPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLSGEVILGDQNVKDIDLNWYRSHIGVVQQEPPLFSGSIRENIQMGKLDATEDEIIKSTQYSNAYDFIMATKETFDTKLGDRGTGFSGGQKQRIAIATALIRDPQLLLLDEATSALDNKSEKLVQKTLDTTIAEGKRTIVMVAHRLQTVRNAD 590
BLAST of SMED30003432 vs. Planmine SMEST
Match: SMESG000027399.1 (SMESG000027399.1) HSP 1 Score: 531.176 bits (1367), Expect = 0.000e+0 Identity = 258/399 (64.66%), Postives = 328/399 (82.21%), Query Frame = -1 Query: 442 VSYYQLFRFATGXXXXXXXXXXXXXICVGAAFPLNVLIFRDVVNLLVSPRDLTMTFSERMRPSVIKFAILSSCTFISGFIQMVTISLTAARQSRRLRSNYFNALLRQEICWFDKQQTGQLVTKLTDDVESIESGISDKLAAFIQQISSFVGCIILAFTTGWKLSFIGSMSIPIMATTFSLMIHFIKKYSIKQIKAYSIAGGIAEEILSSIRTVVAFSAQEKEVKRYSHNLKEAETLGVKRSICQGLGSGVIGFTIFTVGSLVYYMGLLFIYEGSYDPGTVIQIFLTIVIGSIALGNAVPMLENFITAKAAAYPLFQVIDRVPQISHKKHGVIPESFYGDIEFKNVDFEYPTRPGVPILQNFNFTLPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLAGEI 1638 V +++LFRF +D+ ++++M+ISS+ +G A PLNVLIF+DVVNLLV P + F M+ +I FAIL+S I+ F+Q + IS+T RQSRR +SNYF ALLRQEI WFDKQQTGQ++T+ +DD++SIE ISDKLA FIQQIS F+G II++ GWKL+ +G +SIPIM F MI+FIKKY I QI+AYS+AGGIAEEILSS+RTVVAF+AQE EV RYS NL +A++LG+K+SI QG+GSG +G ++F++GSLV+Y+GLL I +YDPGTVIQ+FLTIV+GSI+LG AVP++ENF+TA+AAAY +F+VIDRVP I HKK G+IP++F DI+ +NV FEYPTRPGV IL NFNFT+PYGKTVAFIGPSGSGKSTIIHLLQRFYDPL+GE+ Sbjct: 70 VPFHRLFRFMDSMDVFLIVLMVISSMGLGVALPLNVLIFKDVVNLLVLPPG-NIKFVSAMQNLIIYFAILASGALIASFVQSICISVTGKRQSRRYKSNYFAALLRQEISWFDKQQTGQMITRFSDDIDSIEVAISDKLAQFIQQISLFIGSIIISAINGWKLTLVGCVSIPIMIIVFYFMINFIKKYVIAQIRAYSVAGGIAEEILSSVRTVVAFNAQESEVNRYSKNLVKAKSLGIKKSIVQGIGSGCVGLSVFSIGSLVFYVGLLLINSENYDPGTVIQVFLTIVLGSISLGIAVPIIENFMTAQAAAYSIFEVIDRVPTIDHKKAGIIPDTFASDIKLQNVTFEYPTRPGVTILDNFNFTIPYGKTVAFIGPSGSGKSTIIHLLQRFYDPLSGEV 467 The following BLAST results are available for this feature:
BLAST of SMED30003432 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of SMED30003432 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of SMED30003432 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of SMED30003432 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of SMED30003432 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of SMED30003432 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of SMED30003432 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of SMED30003432 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of SMED30003432 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of SMED30003432 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of SMED30003432 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of SMED30003432 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of SMED30003432 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of SMED30003432 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30003432 ID=SMED30003432|Name=SMED30003432|organism=Schmidtea mediterranea sexual|type=transcript|length=1806bpback to top protein sequence of SMED30003432-orf-1 >SMED30003432-orf-1 ID=SMED30003432-orf-1|Name=SMED30003432-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=602bp FLILFKSVSIFNMGKTSYNVEEANFANSILKEKPAKSKTDIPEAKKEKPKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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