Homeobox domain-containing protein

Overview
NameHomeobox domain-containing protein
Smed IDSMED30003382
Length (bp)1143
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Homeobox domain-containing protein (SMED30003382) t-SNE clustered cells

Violin plots show distribution of expression levels for Homeobox domain-containing protein (SMED30003382) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Homeobox domain-containing protein (SMED30003382) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Homeobox domain-containing protein (SMED30003382) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30003382

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30003382SMESG000047763.1 SmedASXL_018875SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
protonephridiaSMED30003382SMESG000047763.1 dd_Smed_v4_28958_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30003382SMESG000047763.1 dd_Smed_v6_28958_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: SHOX2 (short stature homeobox 2 [Source:HGNC Symbol;Acc:HGNC:10854])

HSP 1 Score: 100.523 bits (249), Expect = 6.776e-25
Identity = 50/79 (63.29%), Postives = 58/79 (73.42%), Query Frame = 2 
Query:  473 SNGVED--MLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            + G+ED      K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:   48 AKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 126
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: SHOX2 (short stature homeobox 2 [Source:HGNC Symbol;Acc:HGNC:10854])

HSP 1 Score: 99.3673 bits (246), Expect = 5.343e-24
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:   10 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 76
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: SHOX (short stature homeobox [Source:HGNC Symbol;Acc:HGNC:10853])

HSP 1 Score: 99.3673 bits (246), Expect = 1.129e-23
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  116 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKG 182
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: SHOX (short stature homeobox [Source:HGNC Symbol;Acc:HGNC:10853])

HSP 1 Score: 99.3673 bits (246), Expect = 1.129e-23
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  116 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKG 182
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: SHOX2 (short stature homeobox 2 [Source:HGNC Symbol;Acc:HGNC:10854])

HSP 1 Score: 100.523 bits (249), Expect = 2.373e-23
Identity = 50/79 (63.29%), Postives = 58/79 (73.42%), Query Frame = 2 
Query:  473 SNGVED--MLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            + G+ED      K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  127 AKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 205
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: alr-1 (AristaLess (Drosophila homeodomain) Related [Source:UniProtKB/TrEMBL;Acc:Q21836])

HSP 1 Score: 87.4261 bits (215), Expect = 7.115e-19
Identity = 40/70 (57.14%), Postives = 51/70 (72.86%), Query Frame = 2 
Query:  473 SNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKR 682
            +N  +D    K RR+R  F+  QL ELE++F +THYPD   REEL+ R+ L+EARVQVWFQNRRAK RK+
Sbjct:  106 TNSPDDNGKRKQRRYRTTFSAFQLDELEKVFARTHYPDVFTREELATRVQLTEARVQVWFQNRRAKYRKQ 175
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-17 (C. Elegans Homeobox; CEH-17 [Source:UniProtKB/TrEMBL;Acc:G5EC89])

HSP 1 Score: 85.1149 bits (209), Expect = 8.449e-19
Identity = 42/67 (62.69%), Postives = 49/67 (73.13%), Query Frame = 2 
Query:  494 LNP----KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKR 682
            LNP    K RR R  FT  QL ELER F +THYPD + REE++ R+ L+EARVQVWFQNRRAK RK+
Sbjct:  141 LNPAERRKQRRIRTTFTSGQLKELERSFCETHYPDIYTREEIAMRIDLTEARVQVWFQNRRAKYRKQ 207
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: unc-4 (Homeobox protein unc-4 [Source:UniProtKB/Swiss-Prot;Acc:P29506])

HSP 1 Score: 84.7297 bits (208), Expect = 1.192e-18
Identity = 48/103 (46.60%), Postives = 58/103 (56.31%), Query Frame = 2 
Query:  449 FHDNNQTMSNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFLSTSPL 757
              D+N T  +        K RR R NF+  QL ELE  F+ +HYPD  +RE L+ RL L E+RVQVWFQNRRAK RKR QN  +N S  I       + T  L
Sbjct:   75 LEDDNDTGESAA------KRRRTRTNFSGWQLEELESAFEASHYPDVFMREALAMRLDLLESRVQVWFQNRRAKWRKREQN--RNGSSEIKKDDGEQMETKAL 169
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-8 (Homeobox protein ceh-8 [Source:UniProtKB/Swiss-Prot;Acc:Q94398])

HSP 1 Score: 82.4185 bits (202), Expect = 1.397e-17
Identity = 46/100 (46.00%), Postives = 61/100 (61.00%), Query Frame = 2 
Query:  485 EDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKR----YQNIEKNQSK----TISHSSENFLSTSPLI 760
            + + + K RR+R  FT  QL  LE  FD+THYPD + RE L+A++ L E RVQVWFQNRRAK R++     Q  EK+  K    + S  SEN   T P++
Sbjct:   51 DKIADKKQRRNRTTFTTFQLHALEAAFDKTHYPDVYARETLAAKVQLPEVRVQVWFQNRRAKFRRQEKQDCQGEEKHSLKDTMPSWSWMSENKTDTPPML 150
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-8 (Homeobox protein ceh-8 [Source:UniProtKB/Swiss-Prot;Acc:Q94398])

HSP 1 Score: 82.0333 bits (201), Expect = 1.695e-17
Identity = 46/100 (46.00%), Postives = 61/100 (61.00%), Query Frame = 2 
Query:  485 EDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKR----YQNIEKNQSK----TISHSSENFLSTSPLI 760
            + + + K RR+R  FT  QL  LE  FD+THYPD + RE L+A++ L E RVQVWFQNRRAK R++     Q  EK+  K    + S  SEN   T P++
Sbjct:   53 DKIADKKQRRNRTTFTTFQLHALEAAFDKTHYPDVYARETLAAKVQLPEVRVQVWFQNRRAKFRRQEKQDCQGEEKHSLKDTMPSWSWMSENKTDTPPML 152
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: CG34367 (gene:FBgn0085396 transcript:FBtr0301049)

HSP 1 Score: 99.3673 bits (246), Expect = 2.146e-23
Identity = 47/71 (66.20%), Postives = 55/71 (77.46%), Query Frame = 2 
Query:  491 MLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            ++N K RR R NFT+ QL ELER+F++THYPDA +REELS RL LSEARVQVWFQNRRAK RK    + K 
Sbjct:   64 LVNTKQRRSRTNFTLDQLNELERLFEETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHENQMHKG 134
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: CG34367 (gene:FBgn0085396 transcript:FBtr0112592)

HSP 1 Score: 99.7525 bits (247), Expect = 7.075e-23
Identity = 47/71 (66.20%), Postives = 55/71 (77.46%), Query Frame = 2 
Query:  491 MLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            ++N K RR R NFT+ QL ELER+F++THYPDA +REELS RL LSEARVQVWFQNRRAK RK    + K 
Sbjct:  187 LVNTKQRRSRTNFTLDQLNELERLFEETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHENQMHKG 257
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: CG9876 (gene:FBgn0034821 transcript:FBtr0071979)

HSP 1 Score: 93.5893 bits (231), Expect = 1.926e-21
Identity = 45/93 (48.39%), Postives = 63/93 (67.74%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFLSTSP-LIENQMTN 778
            KPRR+R  F+  QL  LE++F++THYPDA +REEL+ ++HLSEARVQVWFQNRRAK R+  +++           S   L T+P L+   ++N
Sbjct:  116 KPRRNRTTFSSAQLTALEKVFERTHYPDAFVREELATKVHLSEARVQVWFQNRRAKFRRNERSV----------GSRTLLDTAPQLVPAPISN 198
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: PHDP (gene:FBgn0025334 transcript:FBtr0072224)

HSP 1 Score: 88.5817 bits (218), Expect = 3.546e-20
Identity = 41/69 (59.42%), Postives = 53/69 (76.81%), Query Frame = 2 
Query:  476 NGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKR 682
            +G+      K RR R  FT +QL ELE+IF +THYPD + REE++++LHL+EARVQVWFQNRRAK RK+
Sbjct:  102 DGLSLTDKSKQRRIRTTFTSNQLNELEKIFLETHYPDIYTREEIASKLHLTEARVQVWFQNRRAKFRKQ 170
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: hbn (gene:FBgn0008636 transcript:FBtr0071556)

HSP 1 Score: 86.2705 bits (212), Expect = 2.686e-18
Identity = 55/108 (50.93%), Postives = 65/108 (60.19%), Query Frame = 2 
Query:  455 DNNQTMS----NG--VEDMLNP-KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFLSTSPL 757
            DN+  +S    NG  + DM  P K RR R  FT  QL +LER F++T YPD   RE+L+ RL LSEARVQVWFQNRRAK RKR + +  NQ K      E  L   PL
Sbjct:  129 DNDDELSSSLNNGHDLSDMERPRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKFM--NQDKAGYLLPEQGLPEFPL 234
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: shox2 (short stature homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-040426-1457])

HSP 1 Score: 98.9821 bits (245), Expect = 5.586e-24
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:   41 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 107
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: shox2 (short stature homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-040426-1457])

HSP 1 Score: 99.3673 bits (246), Expect = 2.616e-23
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  107 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 173
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: shox (short stature homeobox [Source:ZFIN;Acc:ZDB-GENE-051030-21])

HSP 1 Score: 98.9821 bits (245), Expect = 2.797e-23
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  108 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKG 174
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: arxa (aristaless related homeobox a [Source:NCBI gene;Acc:30657])

HSP 1 Score: 94.7449 bits (234), Expect = 6.068e-21
Identity = 46/70 (65.71%), Postives = 52/70 (74.29%), Query Frame = 2 
Query:  473 SNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKR 682
            S+  E ML  K RR+R  FT +QL ELER F +THYPD   REEL+ RL L+EARVQVWFQNRRAK RKR
Sbjct:  204 SDSEEGMLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKR 273
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: arxb (aristaless related homeobox b [Source:ZFIN;Acc:ZDB-GENE-121109-2])

HSP 1 Score: 93.2041 bits (230), Expect = 1.293e-20
Identity = 50/106 (47.17%), Postives = 67/106 (63.21%), Query Frame = 2 
Query:  473 SNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQ--------NIEKNQSKTISHSSENFLSTSPLIEN 766
            S+  + ML  K RR+R  FT +QL ELER F +THYPD   REEL+ RL L+EARVQVWFQNRRAK RKR +        ++  + +   + S  ++LS +P + N
Sbjct:  151 SDTEDGMLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKVGVQPHTLSLHYSGAPPAAQSLCHYLSGNPFVPN 256
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: crtac1 (cartilage acidic protein 1 [Source:Xenbase;Acc:XB-GENE-5881785])

HSP 1 Score: 98.9821 bits (245), Expect = 6.847e-24
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:   10 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 76
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: SHOX (short stature homeobox [Source:NCBI gene;Acc:100486480])

HSP 1 Score: 100.908 bits (250), Expect = 1.871e-23
Identity = 54/100 (54.00%), Postives = 62/100 (62.00%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFLSTSPLIENQMTNPDFFLSAL 802
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K     I       L T   +E     P   + AL
Sbjct:  155 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGGYGVI-------LGTGSHLETCRVAPYVNMGAL 247
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: crtac1 (cartilage acidic protein 1 [Source:Xenbase;Acc:XB-GENE-5881785])

HSP 1 Score: 99.7525 bits (247), Expect = 3.757e-23
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  119 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 185
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: ARX (aristaless related homeobox [Source:NCBI gene;Acc:100486727])

HSP 1 Score: 95.5153 bits (236), Expect = 7.390e-21
Identity = 51/102 (50.00%), Postives = 62/102 (60.78%), Query Frame = 2 
Query:  473 SNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTI--------SHSSENFLSTSP 754
            S+  E ML  K RR+R  FT +QL ELER F +THYPD   REEL+ RL L+EARVQVWFQNRRAK RKR +   +  +  +        SH    +L  SP
Sbjct:  290 SDSEEGMLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHAPGLPFPGPLSASHPLGPYLDASP 391
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: ALX1 (ALX homeobox 1 [Source:NCBI gene;Acc:100489661])

HSP 1 Score: 91.2781 bits (225), Expect = 4.860e-20
Identity = 43/71 (60.56%), Postives = 54/71 (76.06%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRK--RYQNIEKNQS 709
            K RRHR  FT  QL ELE++F +THYPD ++RE+L+ R  L+EARVQVWFQNRRAK RK  RY  I++ +S
Sbjct:  131 KKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKS 201
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Shox2 (short stature homeobox 2 [Source:MGI Symbol;Acc:MGI:1201673])

HSP 1 Score: 98.2117 bits (243), Expect = 9.048e-25
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:   10 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 76
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Shox2 (short stature homeobox 2 [Source:MGI Symbol;Acc:MGI:1201673])

HSP 1 Score: 99.3673 bits (246), Expect = 3.668e-24
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:   10 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 76
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Shox2 (short stature homeobox 2 [Source:MGI Symbol;Acc:MGI:1201673])

HSP 1 Score: 99.3673 bits (246), Expect = 3.668e-24
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:   10 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 76
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Shox2 (short stature homeobox 2 [Source:MGI Symbol;Acc:MGI:1201673])

HSP 1 Score: 100.138 bits (248), Expect = 5.291e-24
Identity = 50/79 (63.29%), Postives = 58/79 (73.42%), Query Frame = 2 
Query:  473 SNGVED--MLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            + G+ED      K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:   48 AKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 126
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Shox2 (short stature homeobox 2 [Source:MGI Symbol;Acc:MGI:1201673])

HSP 1 Score: 100.138 bits (248), Expect = 2.526e-23
Identity = 50/79 (63.29%), Postives = 58/79 (73.42%), Query Frame = 2 
Query:  473 SNGVED--MLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            + G+ED      K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  127 AKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 205
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|O35750|SHOX2_RAT (Short stature homeobox protein 2 (Fragment) OS=Rattus norvegicus OX=10116 GN=Shox2 PE=2 SV=2)

HSP 1 Score: 100.138 bits (248), Expect = 3.840e-23
Identity = 50/79 (63.29%), Postives = 58/79 (73.42%), Query Frame = 2 
Query:  473 SNGVED--MLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            + G+ED      K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:   33 AKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 111
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|O60902|SHOX2_HUMAN (Short stature homeobox protein 2 OS=Homo sapiens OX=9606 GN=SHOX2 PE=2 SV=4)

HSP 1 Score: 100.523 bits (249), Expect = 1.380e-22
Identity = 50/79 (63.29%), Postives = 58/79 (73.42%), Query Frame = 2 
Query:  473 SNGVED--MLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            + G+ED      K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  127 AKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 205
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|P70390|SHOX2_MOUSE (Short stature homeobox protein 2 OS=Mus musculus OX=10090 GN=Shox2 PE=2 SV=1)

HSP 1 Score: 100.138 bits (248), Expect = 1.767e-22
Identity = 50/79 (63.29%), Postives = 58/79 (73.42%), Query Frame = 2 
Query:  473 SNGVED--MLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            + G+ED      K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  127 AKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 205
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|O15266|SHOX_HUMAN (Short stature homeobox protein OS=Homo sapiens OX=9606 GN=SHOX PE=1 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 2.056e-22
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  116 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKG 182
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|O42115|ARX_DANRE (Aristaless-related homeobox protein OS=Danio rerio OX=7955 GN=arx PE=2 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 4.581e-20
Identity = 46/70 (65.71%), Postives = 52/70 (74.29%), Query Frame = 2 
Query:  473 SNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKR 682
            S+  E ML  K RR+R  FT +QL ELER F +THYPD   REEL+ RL L+EARVQVWFQNRRAK RKR
Sbjct:  204 SDSEEGMLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKR 273
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A087ZZV9 (Uncharacterized protein OS=Apis mellifera OX=7460 PE=3 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 1.017e-22
Identity = 58/120 (48.33%), Postives = 75/120 (62.50%), Query Frame = 2 
Query:  497 NPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFLSTSPLIENQMTNPDFFLSALAIFNSHISMRSSGNNLNT 856
            N K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK    + K  +  +  +  +  +T   +E     P  +L AL +   H  ++ +G N+ T
Sbjct:   18 NGKQRRSRTNFTLEQLAELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHESQLHKGVAGGMVLAPRSPPAT---LEPCRVAP--YLPALRL---HPPIQGAGGNITT 129
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: E9GEU7 (Homeobox domain-containing protein (Fragment) OS=Daphnia pulex OX=6669 GN=DAPPUDRAFT_34773 PE=4 SV=1)

HSP 1 Score: 100.138 bits (248), Expect = 1.280e-22
Identity = 46/59 (77.97%), Postives = 52/59 (88.14%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRK 679
            KPRR R NFT+ QL ELER+F++THYPDA++REELS RL LSEARVQVWFQNRRAK RK
Sbjct:    3 KPRRSRTNFTLEQLAELERLFEETHYPDAYMREELSQRLGLSEARVQVWFQNRRAKCRK 61
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A1A9WJ37 (Uncharacterized protein OS=Glossina brevipalpis OX=37001 PE=3 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 1.785e-22
Identity = 54/81 (66.67%), Postives = 59/81 (72.84%), Query Frame = 2 
Query:  458 NNQTMSNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEK 700
            NN   SNG    LN K RR R NFT+ QL ELER+F++THYPDA +REELS RL LSEARVQVWFQNRRAK RK    I K
Sbjct:  199 NNCDTSNGSSVTLNNKQRRSRTNFTLEQLNELERLFEETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHENQIHK 279
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A1S3H7X4 (short stature homeobox protein 2-like OS=Lingula unguis OX=7574 GN=LOC106152904 PE=3 SV=1)

HSP 1 Score: 106.301 bits (264), Expect = 1.908e-22
Identity = 49/73 (67.12%), Postives = 57/73 (78.08%), Query Frame = 2 
Query:  485 EDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            ED+   K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   ++K 
Sbjct:  127 EDLPKIKQRRSRTNFTLEQLQELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQESQVQKG 199
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A1A9ZM21 (Homeobox domain-containing protein OS=Glossina pallidipes OX=7398 PE=4 SV=1)

HSP 1 Score: 103.219 bits (256), Expect = 2.500e-22
Identity = 52/82 (63.41%), Postives = 58/82 (70.73%), Query Frame = 2 
Query:  461 NQTMSNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQ 706
            N   SN     LN K RR R NFT+ QL ELER+F++THYPDA +REELS RL LSEARVQVWFQNRRAK RK    I K +
Sbjct:   59 NCDTSNSSSVALNNKQRRSRTNFTLEQLNELERLFEETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHENQIHKGK 140
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: shox (short stature homeobox protein [Source:NCBI gene;Acc:103042484])

HSP 1 Score: 98.9821 bits (245), Expect = 3.128e-23
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  114 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKG 180
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: shox (short stature homeobox protein [Source:NCBI gene;Acc:103042484])

HSP 1 Score: 98.9821 bits (245), Expect = 4.736e-23
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  114 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKG 180
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: shox2 (short stature homeobox 2 [Source:NCBI gene;Acc:103043767])

HSP 1 Score: 99.7525 bits (247), Expect = 6.261e-23
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  187 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 253
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: alx1 (ALX homeobox 1 [Source:NCBI gene;Acc:565176])

HSP 1 Score: 92.4337 bits (228), Expect = 8.368e-21
Identity = 41/76 (53.95%), Postives = 54/76 (71.05%), Query Frame = 2 
Query:  455 DNNQTMSNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKR 682
            D ++       ++ + K RRHR  FT  QL ELE++F +THYPD ++RE+L+ R  L+EARVQVWFQNRRAK RKR
Sbjct:  100 DGDELAEKADSNVTSSKKRRHRTTFTSAQLEELEKVFQKTHYPDVYVREQLAMRTELTEARVQVWFQNRRAKWRKR 175
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: arxa (aristaless related homeobox [Source:NCBI gene;Acc:103042910])

HSP 1 Score: 92.4337 bits (228), Expect = 3.774e-20
Identity = 45/70 (64.29%), Postives = 52/70 (74.29%), Query Frame = 2 
Query:  473 SNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKR 682
            S+  E +L  K RR+R  FT +QL ELER F +THYPD   REEL+ RL L+EARVQVWFQNRRAK RKR
Sbjct:  214 SDSEEGVLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKR 283
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: dmbx1b (diencephalon/mesencephalon homeobox 1b [Source:NCBI gene;Acc:550288])

HSP 1 Score: 77.411 bits (189), Expect = 4.574e-16
Identity = 40/88 (45.45%), Postives = 53/88 (60.23%), Query Frame = 2 
Query:  437 CNS*FHDNNQTMSNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEK 700
            C +   D N T         +P  RR R  FT  QL  LE+ F +THYPD  +RE L+   +L EARVQVWF+NRRAK RK+ ++++K
Sbjct:   20 CVTPGCDINSTTWEARYGTQHPHQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQK 107
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010761.1 (pep scaffold:Pmarinus_7.0:GL476415:928307:936594:-1 gene:ENSPMAG00000009746.1 transcript:ENSPMAT00000010761.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 69.707 bits (169), Expect = 1.606e-15
Identity = 33/60 (55.00%), Postives = 43/60 (71.67%), Query Frame = 2 
Query:  497 NPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSR 676
            N K RR R  FT  QL  LE +F +T YPD  +REE++ +++L E+RVQVWF+NRRAK R
Sbjct:    3 NRKQRRERTTFTRAQLDVLEALFSKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCR 62
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: dlx5a (distal-less homeobox 5a [Source:NCBI gene;Acc:30569])

HSP 1 Score: 61.6178 bits (148), Expect = 9.120e-11
Identity = 37/96 (38.54%), Postives = 55/96 (57.29%), Query Frame = 2 
Query:  476 NGVEDMLNPKP---RRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFLSTSP 754
            +GV  M+N KP   R+ R  ++  QL  L+R F QT Y     R EL+A L L++ +V++WFQNRR+K +K  +N E   ++    SS+     SP
Sbjct:  190 SGVR-MVNGKPKKIRKPRTIYSSFQLAALQRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKLGKNGEMAPAQASPSSSDPMACNSP 284
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: MSX1 (msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391])

HSP 1 Score: 57.7658 bits (138), Expect = 1.423e-10
Identity = 43/119 (36.13%), Postives = 59/119 (49.58%), Query Frame = 2 
Query:  509 RRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIE----KNQSKTISHSSENFLSTS--PLIENQMTNPDFFLSALAIF--NSHISMRSSG 841
            R+ R  FT  QL+ LE  F Q  Y     R E S  L L+E +V++WFQNRRAK+ KR Q  E    K  +K  + SS   L T+  PL      +   +L+A  +F   + + M   G
Sbjct:   15 RKPRTPFTTSQLLALEHKFRQKQYLSIAERAEFSTSLSLTETQVKIWFQNRRAKA-KRLQEAELERLKMAAKPPALSSHFGLPTAFGPLGAPLPAH-GLYLTASGLFARPAGLPMGPMG 131
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 56.6102 bits (135), Expect = 1.658e-10
Identity = 26/59 (44.07%), Postives = 39/59 (66.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRK 679
            KPR+ R  F+ HQL +LER F++  Y     R EL++ L LS+ +V+ W+QNRR K ++
Sbjct:    4 KPRKARTAFSDHQLTQLERSFERQKYLSVQDRMELASSLSLSDTQVKTWYQNRRTKWKR 62
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Yeast
Match: PHO2 (Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002264])

HSP 1 Score: 46.595 bits (109), Expect = 3.858e-6
Identity = 42/155 (27.10%), Postives = 73/155 (47.10%), Query Frame = 2 
Query:  452 HDNNQTMSNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKR-----YQNIEKNQSKTISHSSENFLSTSPLIENQMTNPDFFLSALAIFNSHISMRSSGNNLNTFKQCCTQEYKSFHQV 901
            H N+ + S+   D    +P+R R       L  L+R F+    P    R+++S  + + E  V++WFQNRRAK RK+        I  +QS+ I++  +   + + L+    T+  F    L  F+  I + S  NN   F   C+    S++++
Sbjct:   61 HTNDMSASSNASDSGPQRPKRTRA--KGEALDVLKRKFEINPTPSLVERKKISDLIGMPEKNVRIWFQNRRAKLRKKQHGSNKDTIPSSQSRDIANDYDRGSTDNNLVTTTSTSSIFHDEDLTFFD-RIPLNS--NNNYYFFDICSITVGSWNRM 210
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO40916 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5Q7])

HSP 1 Score: 86.2705 bits (212), Expect = 2.228e-21
Identity = 40/59 (67.80%), Postives = 48/59 (81.36%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRK 679
            K  R+R NFT  QL +LER+F+QTHYPDA  RE L+ +L LSEARVQ+WFQNRRAKSR+
Sbjct:    1 KAPRNRKNFTGDQLRDLERLFEQTHYPDAMTREGLAKKLGLSEARVQIWFQNRRAKSRR 59
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO31796 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWY2])

HSP 1 Score: 87.0409 bits (214), Expect = 2.495e-21
Identity = 40/68 (58.82%), Postives = 48/68 (70.59%), Query Frame = 2 
Query:  479 GVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKR 682
            G +     K RR+R  FT +QL ELER F +THYPD   RE L+ ++ L+EARVQVWFQNRRAK RKR
Sbjct:   22 GKDSTAKRKQRRYRTTFTSYQLEELERAFAKTHYPDVFTREALAVKIDLTEARVQVWFQNRRAKWRKR 89
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO42103 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2G7])

HSP 1 Score: 90.1225 bits (222), Expect = 4.247e-21
Identity = 48/96 (50.00%), Postives = 57/96 (59.38%), Query Frame = 2 
Query:  455 DNNQTMSNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFL 742
            D+     +  ED    K RR R  FT +QL +LER F++T YPD   REEL+ RL LSEARVQVWFQNRRAK RKR         K +   S NF+
Sbjct:    3 DDGSGEESAGEDGKPRKVRRSRTTFTTYQLHQLERAFEKTQYPDVFTREELALRLDLSEARVQVWFQNRRAKWRKR--------EKALGRESPNFM 90
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO47151 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMS9])

HSP 1 Score: 84.7297 bits (208), Expect = 9.067e-21
Identity = 40/69 (57.97%), Postives = 52/69 (75.36%), Query Frame = 2 
Query:  488 DMLNP-----KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRK 679
            D  NP     K RR+R  FT  QL ELE++F++ HYPD  +REEL+A++++SEAR+QVWFQNRRAK RK
Sbjct:    5 DSENPATVRRKQRRNRTTFTKQQLQELEKVFEKKHYPDIALREELAAKINISEARIQVWFQNRRAKWRK 73
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO38926 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBH9])

HSP 1 Score: 87.4261 bits (215), Expect = 1.560e-20
Identity = 39/60 (65.00%), Postives = 48/60 (80.00%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKR 682
            K RR+R  FT +QL E+ER+F +THYPD + RE+L+ R  L+EARVQVWFQNRRAK RKR
Sbjct:   13 KKRRNRTTFTAYQLEEMERVFQKTHYPDVYTREQLALRCALTEARVQVWFQNRRAKWRKR 72
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: shox2 (short stature homeobox 2 [Source:NCBI gene;Acc:101166569])

HSP 1 Score: 99.7525 bits (247), Expect = 1.924e-23
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  109 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 175
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: mog-12 (Medaka OG-12 [Source:NCBI gene;Acc:100049320])

HSP 1 Score: 98.9821 bits (245), Expect = 2.553e-23
Identity = 47/67 (70.15%), Postives = 54/67 (80.60%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K+
Sbjct:  106 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKD 172
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BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: shox2 (short stature homeobox 2 [Source:NCBI gene;Acc:101166569])

HSP 1 Score: 98.5969 bits (244), Expect = 2.742e-23
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  109 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKG 175
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: mog-12 (Medaka OG-12 [Source:NCBI gene;Acc:100049320])

HSP 1 Score: 98.9821 bits (245), Expect = 4.135e-23
Identity = 47/67 (70.15%), Postives = 53/67 (79.10%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKN 703
            K RR R NFT+ QL ELER+FD+THYPDA +REELS RL LSEARVQVWFQNRRAK RK+   + K 
Sbjct:  106 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKG 172
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: alx1 (ALX homeobox 1 [Source:NCBI gene;Acc:101154901])

HSP 1 Score: 93.5893 bits (231), Expect = 3.831e-21
Identity = 43/71 (60.56%), Postives = 54/71 (76.06%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKT 715
            K RRHR  FT  QL ELE++F +THYPD ++RE+L+ R  L+EARVQVWFQNRRAK RKR +  +  Q+KT
Sbjct:  123 KKRRHRTTFTSAQLEELEKVFQKTHYPDVYVREQLAMRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKT 193
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000047763.1 (SMESG000047763.1)

HSP 1 Score: 329.717 bits (844), Expect = 4.397e-114
Identity = 158/158 (100.00%), Postives = 158/158 (100.00%), Query Frame = 2 
Query:  470 MSNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFLSTSPLIENQMTNPDFFLSALAIFNSHISMRSSGNNLNTFKQCCTQEYKSFHQVSNNFNQYILYQNLY 943
            MSNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFLSTSPLIENQMTNPDFFLSALAIFNSHISMRSSGNNLNTFKQCCTQEYKSFHQVSNNFNQYILYQNLY
Sbjct:    1 MSNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFLSTSPLIENQMTNPDFFLSALAIFNSHISMRSSGNNLNTFKQCCTQEYKSFHQVSNNFNQYILYQNLY 158
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000047763.1 (SMESG000047763.1)

HSP 1 Score: 313.538 bits (802), Expect = 8.121e-108
Identity = 151/151 (100.00%), Postives = 151/151 (100.00%), Query Frame = 2 
Query:  491 MLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFLSTSPLIENQMTNPDFFLSALAIFNSHISMRSSGNNLNTFKQCCTQEYKSFHQVSNNFNQYILYQNLY 943
            MLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFLSTSPLIENQMTNPDFFLSALAIFNSHISMRSSGNNLNTFKQCCTQEYKSFHQVSNNFNQYILYQNLY
Sbjct:    1 MLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFLSTSPLIENQMTNPDFFLSALAIFNSHISMRSSGNNLNTFKQCCTQEYKSFHQVSNNFNQYILYQNLY 151
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000080420.1 (SMESG000080420.1)

HSP 1 Score: 90.8929 bits (224), Expect = 8.743e-20
Identity = 44/76 (57.89%), Postives = 54/76 (71.05%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRK--RYQNIEKNQSKTISH 724
            K RR+R  FT+ QL ELE+ F QTHYPD   REEL+ R+ L+EARVQVWFQNRRAK RK  R+Q +++N      H
Sbjct:  140 KQRRNRTTFTMQQLEELEKAFQQTHYPDVFTREELALRISLTEARVQVWFQNRRAKWRKTERFQPLQQNSGINDQH 215
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000080420.1 (SMESG000080420.1)

HSP 1 Score: 89.7373 bits (221), Expect = 1.096e-19
Identity = 44/76 (57.89%), Postives = 54/76 (71.05%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRK--RYQNIEKNQSKTISH 724
            K RR+R  FT+ QL ELE+ F QTHYPD   REEL+ R+ L+EARVQVWFQNRRAK RK  R+Q +++N      H
Sbjct:   29 KQRRNRTTFTMQQLEELEKAFQQTHYPDVFTREELALRISLTEARVQVWFQNRRAKWRKTERFQPLQQNSGINDQH 104
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000080420.1 (SMESG000080420.1)

HSP 1 Score: 89.7373 bits (221), Expect = 1.157e-19
Identity = 44/76 (57.89%), Postives = 54/76 (71.05%), Query Frame = 2 
Query:  503 KPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARLHLSEARVQVWFQNRRAKSRK--RYQNIEKNQSKTISH 724
            K RR+R  FT+ QL ELE+ F QTHYPD   REEL+ R+ L+EARVQVWFQNRRAK RK  R+Q +++N      H
Sbjct:   36 KQRRNRTTFTMQQLEELEKAFQQTHYPDVFTREELALRISLTEARVQVWFQNRRAKWRKTERFQPLQQNSGINDQH 111
The following BLAST results are available for this feature:
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SHOX26.776e-2563.29short stature homeobox 2 [Source:HGNC Symbol;Acc:H... [more]
SHOX25.343e-2470.15short stature homeobox 2 [Source:HGNC Symbol;Acc:H... [more]
SHOX1.129e-2370.15short stature homeobox [Source:HGNC Symbol;Acc:HGN... [more]
SHOX1.129e-2370.15short stature homeobox [Source:HGNC Symbol;Acc:HGN... [more]
SHOX22.373e-2363.29short stature homeobox 2 [Source:HGNC Symbol;Acc:H... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
alr-17.115e-1957.14AristaLess (Drosophila homeodomain) Related [Sour... [more]
ceh-178.449e-1962.69C. Elegans Homeobox; CEH-17 [Source:UniProtKB/TrE... [more]
unc-41.192e-1846.60Homeobox protein unc-4 [Source:UniProtKB/Swiss-Pr... [more]
ceh-81.397e-1746.00Homeobox protein ceh-8 [Source:UniProtKB/Swiss-Pr... [more]
ceh-81.695e-1746.00Homeobox protein ceh-8 [Source:UniProtKB/Swiss-Pr... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG343672.146e-2366.20gene:FBgn0085396 transcript:FBtr0301049[more]
CG343677.075e-2366.20gene:FBgn0085396 transcript:FBtr0112592[more]
CG98761.926e-2148.39gene:FBgn0034821 transcript:FBtr0071979[more]
PHDP3.546e-2059.42gene:FBgn0025334 transcript:FBtr0072224[more]
hbn2.686e-1850.93gene:FBgn0008636 transcript:FBtr0071556[more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
shox25.586e-2470.15short stature homeobox 2 [Source:ZFIN;Acc:ZDB-GENE... [more]
shox22.616e-2370.15short stature homeobox 2 [Source:ZFIN;Acc:ZDB-GENE... [more]
shox2.797e-2370.15short stature homeobox [Source:ZFIN;Acc:ZDB-GENE-0... [more]
arxa6.068e-2165.71aristaless related homeobox a [Source:NCBI gene;Ac... [more]
arxb1.293e-2047.17aristaless related homeobox b [Source:ZFIN;Acc:ZDB... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
crtac16.847e-2470.15cartilage acidic protein 1 [Source:Xenbase;Acc:XB-... [more]
SHOX1.871e-2354.00short stature homeobox [Source:NCBI gene;Acc:10048... [more]
crtac13.757e-2370.15cartilage acidic protein 1 [Source:Xenbase;Acc:XB-... [more]
ARX7.390e-2150.00aristaless related homeobox [Source:NCBI gene;Acc:... [more]
ALX14.860e-2060.56ALX homeobox 1 [Source:NCBI gene;Acc:100489661][more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Shox29.048e-2570.15short stature homeobox 2 [Source:MGI Symbol;Acc:MG... [more]
Shox23.668e-2470.15short stature homeobox 2 [Source:MGI Symbol;Acc:MG... [more]
Shox23.668e-2470.15short stature homeobox 2 [Source:MGI Symbol;Acc:MG... [more]
Shox25.291e-2463.29short stature homeobox 2 [Source:MGI Symbol;Acc:MG... [more]
Shox22.526e-2363.29short stature homeobox 2 [Source:MGI Symbol;Acc:MG... [more]
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BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O35750|SHOX2_RAT3.840e-2363.29Short stature homeobox protein 2 (Fragment) OS=Rat... [more]
sp|O60902|SHOX2_HUMAN1.380e-2263.29Short stature homeobox protein 2 OS=Homo sapiens O... [more]
sp|P70390|SHOX2_MOUSE1.767e-2263.29Short stature homeobox protein 2 OS=Mus musculus O... [more]
sp|O15266|SHOX_HUMAN2.056e-2270.15Short stature homeobox protein OS=Homo sapiens OX=... [more]
sp|O42115|ARX_DANRE4.581e-2065.71Aristaless-related homeobox protein OS=Danio rerio... [more]
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BLAST of Homeobox domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A087ZZV91.017e-2248.33Uncharacterized protein OS=Apis mellifera OX=7460 ... [more]
E9GEU71.280e-2277.97Homeobox domain-containing protein (Fragment) OS=D... [more]
A0A1A9WJ371.785e-2266.67Uncharacterized protein OS=Glossina brevipalpis OX... [more]
A0A1S3H7X41.908e-2267.12short stature homeobox protein 2-like OS=Lingula u... [more]
A0A1A9ZM212.500e-2263.41Homeobox domain-containing protein OS=Glossina pal... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
shox3.128e-2370.15short stature homeobox protein [Source:NCBI gene;A... [more]
shox4.736e-2370.15short stature homeobox protein [Source:NCBI gene;A... [more]
shox26.261e-2370.15short stature homeobox 2 [Source:NCBI gene;Acc:103... [more]
alx18.368e-2153.95ALX homeobox 1 [Source:NCBI gene;Acc:565176][more]
arxa3.774e-2064.29aristaless related homeobox [Source:NCBI gene;Acc:... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dmbx1b4.574e-1645.45diencephalon/mesencephalon homeobox 1b [Source:NCB... [more]
ENSPMAT00000010761.11.606e-1555.00pep scaffold:Pmarinus_7.0:GL476415:928307:936594:-... [more]
dlx5a9.120e-1138.54distal-less homeobox 5a [Source:NCBI gene;Acc:3056... [more]
MSX11.423e-1036.13msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391][more]
barhl21.658e-1044.07BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
PHO23.858e-627.10Homeobox transcription factor; regulatory targets ... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO409162.228e-2167.80Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO317962.495e-2158.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO421034.247e-2150.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO471519.067e-2157.97Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO389261.560e-2065.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
shox21.924e-2370.15short stature homeobox 2 [Source:NCBI gene;Acc:101... [more]
mog-122.553e-2370.15Medaka OG-12 [Source:NCBI gene;Acc:100049320][more]
shox22.742e-2370.15short stature homeobox 2 [Source:NCBI gene;Acc:101... [more]
mog-124.135e-2370.15Medaka OG-12 [Source:NCBI gene;Acc:100049320][more]
alx13.831e-2160.56ALX homeobox 1 [Source:NCBI gene;Acc:101154901][more]
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BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000047763.14.397e-114100.00SMESG000047763.1[more]
SMESG000047763.18.121e-108100.00SMESG000047763.1[more]
SMESG000080420.18.743e-2057.89SMESG000080420.1[more]
SMESG000080420.11.096e-1957.89SMESG000080420.1[more]
SMESG000080420.11.157e-1957.89SMESG000080420.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003382 ID=SMED30003382|Name=Homeobox domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1143bp
CTAGAAAATAAATAAATCATATTATAAATTTAATTTCGAGATAACATACT
GCTTACAAGTAATTAGTAGTGTTAATTAATAAAAATAACGGATTAATCGG
ATGAGTGAGAATGGTTATACGATATATTGGATTGAGCATTGGACAATGTC
TGACAGCCATAGAGGCAATATGATAACGTTAGAGAGTTTGTAATTGAATG
ATACTTCTAATTGAATTATGTAGCTTGCTCGTTGTAGTGAGTTCAGGACA
GGCAAGTATCTCCAAGCCGAGTAATCGGATAAGCATTACTCAGTTGTCAA
ATTAGATGGTCAAGGTGATAAGCGCCATGTTTTCTGATTTCAATATTTGG
ATCTTATTGGAATTAGTGGCTTGTGTGACTTATAAAATCGTTTAATTTTA
TAACCAATCGTAATGGCTTAATTGTCGTATAAGAAATGCAACAGTTAATT
TCATGATAATAATCAAACAATGTCGAATGGTGTTGAAGATATGTTGAATC
CAAAACCCAGGCGGCATCGTGTGAATTTTACTGTTCATCAATTGATGGAA
CTAGAGAGGATTTTTGATCAAACACATTATCCTGATGCTCATATACGGGA
AGAATTGAGTGCTAGGTTGCATTTATCGGAAGCTCGTGTACAAGTATGGT
TTCAAAATCGTCGAGCTAAAAGTCGAAAACGCTATCAAAACATTGAAAAG
AATCAATCAAAAACAATTTCACATTCCTCAGAAAACTTTCTATCGACGTC
TCCGTTAATTGAAAATCAAATGACGAATCCAGATTTTTTCCTATCTGCTC
TGGCTATTTTCAATTCTCACATTTCTATGAGATCATCGGGCAATAATTTA
AATACTTTCAAACAGTGCTGCACCCAGGAATACAAATCATTTCATCAAGT
ATCCAACAATTTCAATCAGTATATTCTTTATCAAAACCTTTATCAAATGA
TTCAACAAATGATCCACCAGAATCAACAATAAAAAAATCCATTCAATGAA
CTTAAAAATGAAAAGAAAAAATCAAAATCAAATAGTAAATCTATATTTAA
AAAAGAAACAGTTAAACTTTCCCATATTATAATAATTTTAAAAATAAAAG
TACTGATCGGCTTGAAAACAACAATTATTATCCTATTACTACA
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protein sequence of SMED30003382-orf-1

>SMED30003382-orf-1 ID=SMED30003382-orf-1|Name=SMED30003382-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=171bp
MSNGVEDMLNPKPRRHRVNFTVHQLMELERIFDQTHYPDAHIREELSARL
HLSEARVQVWFQNRRAKSRKRYQNIEKNQSKTISHSSENFLSTSPLIENQ
MTNPDFFLSALAIFNSHISMRSSGNNLNTFKQCCTQEYKSFHQVSNNFNQ
YILYQNLYQMIQQMIHQNQQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR001356Homeobox_dom
IPR009057Homeobox-like_sf
IPR017970Homeobox_CS
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0043565sequence-specific DNA binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
GO:0007275multicellular organism development
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001356Homeobox domainSMARTSM00389HOX_1coord: 13..75
e-value: 1.7E-25
score: 100.7
IPR001356Homeobox domainPFAMPF00046Homeodomaincoord: 14..70
e-value: 4.6E-24
score: 84.0
IPR001356Homeobox domainPROSITEPS50071HOMEOBOX_2coord: 11..71
score: 19.921
IPR001356Homeobox domainCDDcd00086homeodomaincoord: 14..71
e-value: 6.74665E-21
score: 78.8244
NoneNo IPR availableGENE3DG3DSA:1.10.10.60coord: 2..74
e-value: 5.3E-28
score: 98.5
NoneNo IPR availablePANTHERPTHR24329FAMILY NOT NAMEDcoord: 2..132
NoneNo IPR availablePANTHERPTHR24329:SF521HOMEOBOX PROTEIN ARXcoord: 2..132
IPR017970Homeobox, conserved sitePROSITEPS00027HOMEOBOX_1coord: 46..69
IPR009057Homeobox-like domain superfamilySUPERFAMILYSSF46689Homeodomain-likecoord: 8..73