Spectrin beta chain
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30003374 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Spectrin beta chain vs. Ensembl Human
Match: SPTBN1 (spectrin beta, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11275]) HSP 1 Score: 1352.42 bits (3499), Expect = 0.000e+0 Identity = 842/2393 (35.19%), Postives = 1368/2393 (57.17%), Query Frame = 1
Query: 160 DEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDI-------RSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKAS-KYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMI-DENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFIN------EALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSA-SRPMRQVNPSNTNPSTTQSHPNLSSSL 7245
D D+ N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R +N +K ++ Y + CD +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RLL KH+ FE E+S + E + EG+ ++ G E I + I+ W L + RK +L E +Q+ +D DD + W+ + ++ +G T+ L++K++ E + NYR ++ + QA S L + V +L IE++Y+++ ++ ++ L D L +Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ +G+P+ + I QD LN W++ ++VD K+D LLS N+ ++C +T WIREK K+IES +LG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L + WE ++ +++R+++L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + F D +Q E LN QE L + L + + E F+ M ++E+ + V++ G+ L+ + N+ DR+Q K ++D+R +KN A +LK+ L + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q ++ P + + + L L+ W L + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK ++E +KK +E L+ ++ L Q+ ++L Q K M+ L E K ++ K I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ ++D + + +Q ++ D + L + + LK+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ + + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N DELI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A++SL E R++ ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW++ QE YL++ +G ++DE L+K+ F+K+ +E+F L+RLTT+E+ + + + E + + AE + + T + + + Q + R ++D+ SE+ + Q+ +S++S P P S +++K P+ SA+ PA T+ P + M+G L RKH+WE N+KAS+R+WH++Y +++ M F+KD + Y E+P+ L E V A DY K+ VF++R +G EYLFQ +M W+ AI+SA S +V+ S + + L +S+
Sbjct: 26 DVDDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLVLSQDYGKHLLGVEDLLQKHTLVEADIGIQAERVRGVNASAQKFATDGEGY-KPCD-----------PQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRPTLDTLHEQA-SALPQEHAESPDVRGRLSGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSEKEIKAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLA---------HTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNRETASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQALSQEGKSTDEVDSKRLTVQTKF-MELLEPLNERKHNLLASKEI-HQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIK------KNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGLLIEETEKRHRRLEEAHRAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLD------ERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVNHLADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKSLLDACESRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPEPSTKVSEEAESQ---------QQWDTSKGEQVSQNGLPAEQGSPRMAETVDT-----SEMVNGATEQRTSSKESSPIPSPTSD--------RKAKTALPAQ---------------SAATLPARTQETPSAQ--MEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKTAASGIP--YHSEVPVSLKEAVCEVALDYKKKKHVFKLRLNDGNEYLFQAKDDEEMNTWIQAISSAISSDKHEVSASTQSTPASSRAQTLPTSV 2333
BLAST of Spectrin beta chain vs. Ensembl Human
Match: SPTBN1 (spectrin beta, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11275]) HSP 1 Score: 1351.27 bits (3496), Expect = 0.000e+0 Identity = 840/2395 (35.07%), Postives = 1363/2395 (56.91%), Query Frame = 1
Query: 160 DEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDI-------RSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDS---HNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMI-DENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFIN------EALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSA-SRPMRQVNPSNTNPSTTQSHPNLSSSL 7245
D D+ N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R +N +K ++ Y + CD +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RLL KH+ FE E+S + E + EG+ ++ G E I + I+ W L + RK +L E +Q+ +D DD + W+ + ++ +G T+ L++K++ E + NYR ++ + QA S L + V +L IE++Y+++ ++ ++ L D L +Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ +G+P+ + I QD LN W++ ++VD K+D LLS N+ ++C +T WIREK K+IES +LG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L + WE ++ +++R+++L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + F D +Q E LN QE L + L + + E F+ M ++E+ + V++ G+ L+ + N+ DR+Q K ++D+R +KN A +LK+ L + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q ++ P + + + L L+ W L + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK + N KK++ E L ++ ++L Q K M+ L E K ++ K I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ ++D + + +Q ++ D + L + + LK+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ + + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N DELI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A++SL E R++ ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW++ QE YL++ +G ++DE L+K+ F+K+ +E+F L+RLTT+E+ + + + E + + AE + + T + + + Q + R ++D+ SE+ + Q+ +S++S P P S +++K P+ SA+ PA T+ P + M+G L RKH+WE N+KAS+R+WH++Y +++ M F+KD + Y E+P+ L E V A DY K+ VF++R +G EYLFQ +M W+ AI+SA S +V+ S + + L +S+
Sbjct: 26 DVDDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLVLSQDYGKHLLGVEDLLQKHTLVEADIGIQAERVRGVNASAQKFATDGEGY-KPCD-----------PQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRPTLDTLHEQA-SALPQEHAESPDVRGRLSGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSEKEIKAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLA---------HTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNRETASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQATMLENQMEVRKKEIEELQSQAQALSQEGKSTDEVDSKRLTVQTKF-MELLEPLNERKHNLLASKEI-HQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIK------KNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGLLIEETEKRHRRLEEAHRAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLD------ERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHFTMLQERFREFARDTGNIGQERVDTVNHLADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKSLLDACESRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPEPSTKVSEEAESQ---------QQWDTSKGEQVSQNGLPAEQGSPRMAETVDT-----SEMVNGATEQRTSSKESSPIPSPTSD--------RKAKTALPAQ---------------SAATLPARTQETPSAQ--MEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKTAASGIP--YHSEVPVSLKEAVCEVALDYKKKKHVFKLRLNDGNEYLFQAKDDEEMNTWIQAISSAISSDKHEVSASTQSTPASSRAQTLPTSV 2335
BLAST of Spectrin beta chain vs. Ensembl Human
Match: SPTBN1 (spectrin beta, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11275]) HSP 1 Score: 1257.28 bits (3252), Expect = 0.000e+0 Identity = 753/2075 (36.29%), Postives = 1217/2075 (58.65%), Query Frame = 1
Query: 211 SRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDI-------RSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKAS-KYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMI-DENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKF 6363
R K L DERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R +N +K ++ Y + CD +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RLL KH+ FE E+S + E + EG+ ++ G E I + I+ W L + RK +L E +Q+ +D DD + W+ + ++ +G T+ L++K++ E + NYR ++ + QA S L + V +L IE++Y+++ ++ ++ L D L +Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ +G+P+ + I QD LN W++ ++VD K+D LLS N+ ++C +T WIREK K+IES +LG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L + WE ++ +++R+++L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + F D +Q E LN QE L + L + + E F+ M ++E+ + V++ G+ L+ + N+ DR+Q K ++D+R +KN A +LK+ L + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q ++ P + + + L L+ W L + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK ++E +KK +E L+ ++ L Q+ ++L Q K M+ L E K ++ K I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ ++D + + +Q ++ D + L + + LK+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ + + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N DELI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A++SL E R++ ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW++ QE YL++ +G ++DE L+K+ F+K+ +E+F
Sbjct: 30 GRFKQLQDEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLVLSQDYGKHLLGVEDLLQKHTLVEADIGIQAERVRGVNASAQKFATDGEGY-KPCD-----------PQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRPTLDTLHEQA-SALPQEHAESPDVRGRLSGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSEKEIKAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLA---------HTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNRETASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQALSQEGKSTDEVDSKRLTVQTKF-MELLEPLNERKHNLLASKEI-HQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIK------KNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGLLIEETEKRHRRLEEAHRAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLD------ERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVNHLADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKSLLDACESRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERF 2060
BLAST of Spectrin beta chain vs. Ensembl Human
Match: SPTBN2 (spectrin beta, non-erythrocytic 2 [Source:HGNC Symbol;Acc:HGNC:11276]) HSP 1 Score: 1252.65 bits (3240), Expect = 0.000e+0 Identity = 792/2375 (33.35%), Postives = 1295/2375 (54.53%), Query Frame = 1
Query: 193 SKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCD--QDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEAL--INIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKR---PQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAIN--------SASRPMRQVNPSNTNPSTTQSHPNLSSSLPP 7251
+++FERSRIKALADERE VQKKTFTKW+NS L VT ++ DLY DLRDG+ LL LLE+LS EI+PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RLTLGL+WTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VN+ NFT SWR GL F A++HKHRPDL+DF S + + NL AF++AE LG+ LLDPEDVNV PDE+S+ITYVA+YYHYF+ +KA +V KR+ K+L+ +E E++++ Y+SL S+LL+WI TI LN RQ +NS+ G+Q Q+ +FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KAA+RE+W+++N L+ + + G L V AA++KHEAIETDI AY + + ++ L E Y+DI I ++ V LW L Q + RRE L L++ + + + + + + + + G+HL VE+LL+ HEL+E+DI +R+ + + A R FC+ +++R + ++ E+ + + L + R+ L+ S +W+F+ + E W++E ++ + D G DL+ RLL KH E+S + L+ L +G+ LV G +A+ ++Q WE L E R +L + YQ+ +D +D E W+ + RL LG T+ L R+++ E + ++R ++ +R QA + L ++ V ++ +E+ Y++L A + L AL +Y +L+++ + W+ EK+++L + +E+LEV++ RFE E E+ A ++ VN+++E L+ P IVN Q+ LN+ W + + D K+ L S N+ ++C +T W+REK K+IES LG DL V+ QR++ +RD+ AI A++ L + + + + A I +L V WE L+ +R R+ +L + F++ LDDF WLG+ QT +AS+ P + EAE L+ ++ + R E+ + + +G++ + + D Q + L+ R+E++ W+ L + E ++ RL + F DARQ E +L++QE L + L + + + + E F+ M ++ + + +L+ G+ L+ E N++ D+++ K +++ R KKN AAQ +L++ LQD +L + EK+ ++S ++ + + +A E+ A + +++++K G++ + + P K + + L +L+ W EL + K ++L NR +LF +S ++ WL++++ Q+ +DD +TS+ LKK E+ ++K +E ++ ++ L Q++ A + E+ V+ L P+ + QF +D +DEI W+ E++ + + ME L Q L ++++++ EI+ ++ L +E QR L A + +L++ + L E+E L + L Q+F D +E +W+ E+EL +MG +KD+ + ++K Q LE + +Y I + S + P+ + ++ V+ + LK + E++ + + C ++E WI ER +A S + G+D + T+LRD+F FS +T+ IG +V+ AN + LI G H +++ WKD +NE WADLLEL+DTR Q+L +A++L R+ ++ L +Q K+ ++ + G+D + LQR+ +E D+ L + + L Y DK + + Q + +A+ L+ R+ L+ D F VREL+ W++EV +QM+ + +PRDVS +L++ N + +K E++++ + FS C+++G+ LL H + EI K ++ +R +KW +D L L++EV + RDA AEAW+ SQE + + LG T+DE +L+K+ FQK+ + EE+F L++LT +E R K+ R+ E TA +++ T + T++ P Q S++ + Q++ P P S + P+ ++ R P PS M + S ST+ A+ P P + M+G L RK + E +KA+NR+W ++Y +L + + F+KD + Y E+P+ L + A DY KR VF++ ++G EYLFQ +M+ W+ +N ++ P V PS T T + ++PP
Sbjct: 40 ARLFERSRIKALADEREAVQKKTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQEKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDLLYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALR---FCNPGKEYRPC----DPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQQHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASARAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEFSTQALARQHRALEEEIRSHRPTLDALREQA-AALPPTLSRTPEVQSRVPTLERHYEELQARAGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSIQNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTREANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADP-QCLFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVL---------SHTEMPGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRHKKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLFDANRAELFAQSCCALESWLESLQAQLHSDD----YGKDLTSVNILLKKQQMLEWEMAVREKEVEAIQAQAKALAQED-QGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDEILWVTERLPM----ASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADL-RERQRA-----LGAAAAGPELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQE-KAKDELSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLKELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALARVQHKQ--QQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQDDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYAAEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPAPEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQ-------APSVNGVCTDGEPSQPLLGQQRLEHSSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQ-----SRSTESAHAATLPPRG-PEPSAQEQMEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVP--YHGEVPVSLARAQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEPVVPSTTRGMTR------AMTMPP 2357
BLAST of Spectrin beta chain vs. Ensembl Human
Match: SPTBN2 (spectrin beta, non-erythrocytic 2 [Source:HGNC Symbol;Acc:HGNC:11276]) HSP 1 Score: 1252.65 bits (3240), Expect = 0.000e+0 Identity = 792/2375 (33.35%), Postives = 1295/2375 (54.53%), Query Frame = 1
Query: 193 SKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCD--QDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEAL--INIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKR---PQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAIN--------SASRPMRQVNPSNTNPSTTQSHPNLSSSLPP 7251
+++FERSRIKALADERE VQKKTFTKW+NS L VT ++ DLY DLRDG+ LL LLE+LS EI+PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RLTLGL+WTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VN+ NFT SWR GL F A++HKHRPDL+DF S + + NL AF++AE LG+ LLDPEDVNV PDE+S+ITYVA+YYHYF+ +KA +V KR+ K+L+ +E E++++ Y+SL S+LL+WI TI LN RQ +NS+ G+Q Q+ +FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KAA+RE+W+++N L+ + + G L V AA++KHEAIETDI AY + + ++ L E Y+DI I ++ V LW L Q + RRE L L++ + + + + + + + + G+HL VE+LL+ HEL+E+DI +R+ + + A R FC+ +++R + ++ E+ + + L + R+ L+ S +W+F+ + E W++E ++ + D G DL+ RLL KH E+S + L+ L +G+ LV G +A+ ++Q WE L E R +L + YQ+ +D +D E W+ + RL LG T+ L R+++ E + ++R ++ +R QA + L ++ V ++ +E+ Y++L A + L AL +Y +L+++ + W+ EK+++L + +E+LEV++ RFE E E+ A ++ VN+++E L+ P IVN Q+ LN+ W + + D K+ L S N+ ++C +T W+REK K+IES LG DL V+ QR++ +RD+ AI A++ L + + + + A I +L V WE L+ +R R+ +L + F++ LDDF WLG+ QT +AS+ P + EAE L+ ++ + R E+ + + +G++ + + D Q + L+ R+E++ W+ L + E ++ RL + F DARQ E +L++QE L + L + + + + E F+ M ++ + + +L+ G+ L+ E N++ D+++ K +++ R KKN AAQ +L++ LQD +L + EK+ ++S ++ + + +A E+ A + +++++K G++ + + P K + + L +L+ W EL + K ++L NR +LF +S ++ WL++++ Q+ +DD +TS+ LKK E+ ++K +E ++ ++ L Q++ A + E+ V+ L P+ + QF +D +DEI W+ E++ + + ME L Q L ++++++ EI+ ++ L +E QR L A + +L++ + L E+E L + L Q+F D +E +W+ E+EL +MG +KD+ + ++K Q LE + +Y I + S + P+ + ++ V+ + LK + E++ + + C ++E WI ER +A S + G+D + T+LRD+F FS +T+ IG +V+ AN + LI G H +++ WKD +NE WADLLEL+DTR Q+L +A++L R+ ++ L +Q K+ ++ + G+D + LQR+ +E D+ L + + L Y DK + + Q + +A+ L+ R+ L+ D F VREL+ W++EV +QM+ + +PRDVS +L++ N + +K E++++ + FS C+++G+ LL H + EI K ++ +R +KW +D L L++EV + RDA AEAW+ SQE + + LG T+DE +L+K+ FQK+ + EE+F L++LT +E R K+ R+ E TA +++ T + T++ P Q S++ + Q++ P P S + P+ ++ R P PS M + S ST+ A+ P P + M+G L RK + E +KA+NR+W ++Y +L + + F+KD + Y E+P+ L + A DY KR VF++ ++G EYLFQ +M+ W+ +N ++ P V PS T T + ++PP
Sbjct: 40 ARLFERSRIKALADEREAVQKKTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQEKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDLLYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALR---FCNPGKEYRPC----DPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQQHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASARAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEFSTQALARQHRALEEEIRSHRPTLDALREQA-AALPPTLSRTPEVQSRVPTLERHYEELQARAGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSIQNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTREANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADP-QCLFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVL---------SHTEMPGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRHKKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLFDANRAELFAQSCCALESWLESLQAQLHSDD----YGKDLTSVNILLKKQQMLEWEMAVREKEVEAIQAQAKALAQED-QGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDEILWVTERLPM----ASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADL-RERQRA-----LGAAAAGPELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQE-KAKDELSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLKELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALARVQHKQ--QQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQDDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYAAEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPAPEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQ-------APSVNGVCTDGEPSQPLLGQQRLEHSSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQ-----SRSTESAHAATLPPRG-PEPSAQEQMEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVP--YHGEVPVSLARAQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEPVVPSTTRGMTR------AMTMPP 2357
BLAST of Spectrin beta chain vs. Ensembl Celegans
Match: unc-70 (Spectrin beta chain [Source:UniProtKB/TrEMBL;Acc:E0AHA7]) HSP 1 Score: 1348.57 bits (3489), Expect = 0.000e+0 Identity = 843/2398 (35.15%), Postives = 1341/2398 (55.92%), Query Frame = 1
Query: 139 DYQNALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKD--IQSLINNFNTSKSNLLSLNEIVNENEIFIDKM-LSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPDEYKGIVK-------DVEDNFNSLKIICAEKKTE----ISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFS 7290
D + +DE N ++++FERSRIKALADERE VQKKTFTKW+NS L+ V+ K++DLY+D+RDGK LL LL +LS E +PKPT G+MRIHCLENV+K L FL NQ VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI F++ + +SAK+ALLLWCQMKTAGYP+VN++NF+ SWR GL F ALIHKHRPDL+D+ + +++ + NL AFD AEN LG+ LD EDVNV PDE+S+ITYV +YYHYFN LK ++ KR+ K++N+++E+++MI Y++L S LLEWI I+LLN R F N++ G+Q+Q+ FN YRT EKP KF EK +LEVLLFT++S + + + P E ++ IN AW L AE+ RE L++EL+RQEKL LA +FN+KA +RE+W+T+N L+ + + GN+L +V AA KKHEAIETDI+AYEE + + ++ LE E Y+D I K VL LW L Q L RR L+ + + + ++ ++ I ++ ++ G HLM+VE+LL+ H L+ESDI I +R+ I++A R+ + D S I E+ + K + ELLD +RK L+ + + QF D + E IKE ++++ D G D+ +V LL KHK E L L+ + GK L D S G + I + +I++ L + + SRK +L ++YYQ+ +D DD + ++ + R+ + +G ++L++K+ + ++N+ +I+ + +A+S L +H + ++LD K+ +L +++ +++L+DAL++Y+L +D+DSV SWI EK K L +P DIEE+E++KHRF+ E ++ + KV +VN+L+ L+ +PN I++ Q+ LN W ++ D+VD KR+EL + F +DCQ+T+ WI +K +++E D L DL VM+ QRR++ M+RD+ AI+AK+D L + D+I R + A+ I + +HQ W+IL + +R+ ++ L D+ RF++ LD F WL Q ++AS+ P+S +EAE+L+N++ + R+E+ + ++ +G D + +Q Q++ L+ R+ + + W+ L + + ++ L + L MF DA+Q E +L+ QE YL KD QSL N K ++ FI M +DEK+ A+ + G L + + D++ K +N+DER N AQ KLK+ + L + L D D+L + + EK+ + + + K+ S + +A + E+ A + +++L D P + I ++ L + W EL K EEK Q L NR++L+ +S M +W +E ++ +D+P +T++ ++K E+ K + ++ L + L++ +PD+ + V+ + L PL+ + +K A QF +D DDE W++E++ L +K +L +LQ + + NEI N ++ + Q +IDE H + +L+ + L E ++ + L +FL D E +W+SE+EL +M KD+ + I+K + L+ +I + I +E + + +E + L+ + E++ + L+ ++ + +L Q WI ++ +A S ++G+D + +L++RF F+ +T IGS +V AN D LI H A +I++WKD +NE W +LLEL+DTR Q+L+++ LH++Y D + L I EK +M +DLG+D SV L RK +N+ KD+ + + + L Y DK + + E++ A+R LR + + R ++ +D F++MVR+LL W++EV +M + +P+DVSG+ELL+ NH+SLK E+D++EENF+ C++LGR LL KH S EI+ K ++T +R + ++W + ++L L++EVYQ+ARDAA AE+W+ +QE YL ++ G L+ET+ L+KK F+K+ QEE+F L++LTT E++ E E+TA+ I + + P F + D D++I S+L + KR S S +L+ + S PK A +G L RKH +E+ ++KA+NR+W LY +L Q+ ++F+KD +H E E P+ L A DY K+ V +R GAEYLFQ S DM RW+ + A+ + S S +LP + K FFS
Sbjct: 5 DGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERVQAVVAVAGELEAENYHDQAKINERKENVLQLWNYLFQLLLARRVRLELSMAIQKIFHDMLLTLDLMDDIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRF-RNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAES-LPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMG-DRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR-----------HQDFITTMDANDEKIRAVGMF-GDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQP----GDLTTVNVAMQKQHLIETEMIKKAQHIDQLMEMEPQLEELHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVL----AKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQ-DERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDLSKERRKRLEETLELYALHREIDDLLQ----WIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAM--PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELK------------ETQHREEETAKRRGPAHIGSPSRST------PAAETSF--------------GAQDDDADIT--------------------HSSLEGHRKSSHEKRLAHSESSSWRKSLARAPKFDSKDPKGAKQGEA------FEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDES----VHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASR------------SQTLPAEGSATKKKGGFFS 2298
BLAST of Spectrin beta chain vs. Ensembl Celegans
Match: unc-70 (Spectrin beta chain [Source:UniProtKB/TrEMBL;Acc:E0AHA7]) HSP 1 Score: 1332.78 bits (3448), Expect = 0.000e+0 Identity = 837/2398 (34.90%), Postives = 1332/2398 (55.55%), Query Frame = 1
Query: 139 DYQNALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKD--IQSLINNFNTSKSNLLSLNEIVNENEIFIDKM-LSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPDEYKGIVKDV-------EDNFNSLKIICAEKKTEIS----LFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFS 7290
D + +DE N ++++FERSRIKALADERE VQKKTFTKW+NS L+ V+ K++DLY+D+RDGK LL LL +LS E +PKPT G+MRIHCLENV+K L FL NQ VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI F++ + +SAK+ALLLWCQMKTAGYP+VN++NF+ SWR GL F ALIHKHRPDL+D+ + +++ + NL AFD AEN LG+ LD EDVNV PDE+S+ITYV +YYHYFN LK ++ KR+ K++N+++E+++MI Y++L S LLEWI I+LLN R F N++ G+Q+Q+ FN YRT EKP KF EK +LEVLLFT++S + + + P E ++ IN AW L AE+ RE L++EL+RQEKL LA +FN+KA +RE+W+T+N L+ + + GN+L +V AA KKHEAIETDI+AYEE + + ++ LE E Y+D I K VL LW L Q L RR L+ + + + ++ ++ I ++ ++ G HLM+VE+LL+ H L+ESDI I +R+ I++A R+ + D S I E+ + K + ELLD +RK L+ + + QF D + E IKE ++++ D G D+ +V LL KHK E L L+ + GK L D S G + I + +I++ L + + SRK +L ++YYQ+ +D DD + ++ + R+ + +G ++L++K+ + ++N+ +I+ + +A+SL +H + ++LD K+ +L +++ +++L+DAL++Y+L +D+DSV SWI EK K L +P DIEE+E++KHRF+ E ++ + KV +VN+L+ L+ +PN I++ Q+ LN W ++ D+VD KR+EL + F +DCQ+T+ WI +K +++E D L DL VM+ QRR++ M+RD+ AI+AK+D L + D+I R + A+ I + +HQ W+IL + +R+ ++ L D+ RF++ LD F WL Q ++AS+ P+S +EAE+L+N++ + R+E+ + ++ +G D + +Q Q++ L+ R+ + + W+ L + + ++ L + L MF DA+Q E +L+ QE YL KD QSL N K + + FI M +DEK+ A+ + G L + + D++ K +N+DER N AQ KLK+ + L + L D D+L + + EK+ + + + K+ S + +A + E+ A + +++L D P + I ++ L + W EL K EEK Q L NR++L+ +S M +W +E ++ +D+P +T++ ++K E+ K + ++ L + L++ +PD+ + V+ + L PL+ + +K A QF +D DDE W++E++ L +K +L +LQ + + NEI N ++ + Q +IDE H + +L+ + L E ++ + L +FL D E +W+SE+EL +M KD+ + I+K + L+ +I + I +E + + + E + L+ + E++ + L+ ++ + +L Q WI ++ +A S ++G+D + +L++RF F+ +T IGS +V AN D LI H A +I++WKD +NE W +LLEL+DTR Q+L+++ LH++Y D + L I EK +M +DLG+D SV L RK +N+ KD+ + + + L Y DK + + E++ A+R LR + + R ++ +D F++MVR+LL W++EV +M + +P+DVSG+ELL+ NH+SLK E+D++EENF+ C++LGR LL KH S EI+ K ++T +R + ++W + ++L L++EVYQ+ARDAA AE+W+ +QE YL ++ G L+ET+ L+KK F+K+ F Q +R + E + TFE K HR E + RR + S + + +T + + + KR S S +L+ + S PK A +G L RKH +E+ ++KA+NR+W LY +L Q+ ++F+KD +H E E P+ L A DY K+ V +R GAEYLFQ S DM RW+ + A+ + S S +LP + K FFS
Sbjct: 5 DGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERVQAVVAVAGELEAENYHDQAKINERKENVLQLWNYLFQLLLARRVRLELSMAIQKIFHDMLLTLDLMDDIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRF-RNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESL-PQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMG-DRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRH-----------QDFITTMDANDEKIRAVGMF-GDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQP----GDLTTVNVAMQKQHLIETEMIKKAQHIDQLMEMEPQLEELHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVL----AKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQ-DERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDLSKERRKRLEETLELYALHREIDDLLQ----WIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAM--PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKS------AFAQEERFLAL-------------------------------------EKLTTFELKETQHREEETAK---RRGPAHIGSPSRSTPAAETSFGAQDDE-----------------------KRLAHSESSSWRKSLARAPKFDSKDPKGAKQGEA------FEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDES----VHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASR------------SQTLPAEGSATKKKGGFFS 2281
BLAST of Spectrin beta chain vs. Ensembl Celegans
Match: unc-70 (Spectrin beta chain [Source:UniProtKB/TrEMBL;Acc:E0AHA7]) HSP 1 Score: 1294.26 bits (3348), Expect = 0.000e+0 Identity = 772/2101 (36.74%), Postives = 1236/2101 (58.83%), Query Frame = 1
Query: 139 DYQNALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKD--IQSLINNFNTSKSNLLSLNEIVNENEIFIDKM-LSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPDEYKGIVK-------DVEDNFNSLKIICAEKKTE----ISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIR 6399
D + +DE N ++++FERSRIKALADERE VQKKTFTKW+NS L+ V+ K++DLY+D+RDGK LL LL +LS E +PKPT G+MRIHCLENV+K L FL NQ VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI F++ + +SAK+ALLLWCQMKTAGYP+VN++NF+ SWR GL F ALIHKHRPDL+D+ + +++ + NL AFD AEN LG+ LD EDVNV PDE+S+ITYV +YYHYFN LK ++ KR+ K++N+++E+++MI Y++L S LLEWI I+LLN R F N++ G+Q+Q+ FN YRT EKP KF EK +LEVLLFT++S + + + P E ++ IN AW L AE+ RE L++EL+RQEKL LA +FN+KA +RE+W+T+N L+ + + GN+L +V AA KKHEAIETDI+AYEE + + ++ LE E Y+D I K VL LW L Q L RR L+ + + + ++ ++ I ++ ++ G HLM+VE+LL+ H L+ESDI I +R+ I++A R+ + D S I E+ + K + ELLD +RK L+ + + QF D + E IKE ++++ D G D+ +V LL KHK E L L+ + GK L D S G + I + +I++ L + + SRK +L ++YYQ+ +D DD + ++ + R+ + +G ++L++K+ + ++N+ +I+ + +A+S L +H + ++LD K+ +L +++ +++L+DAL++Y+L +D+DSV SWI EK K L +P DIEE+E++KHRF+ E ++ + KV +VN+L+ L+ +PN I++ Q+ LN W ++ D+VD KR+EL + F +DCQ+T+ WI +K +++E D L DL VM+ QRR++ M+RD+ AI+AK+D L + D+I R + A+ I + +HQ W+IL + +R+ ++ L D+ RF++ LD F WL Q ++AS+ P+S +EAE+L+N++ + R+E+ + ++ +G D + +Q Q++ L+ R+ + + W+ L + + ++ L + L MF DA+Q E +L+ QE YL KD QSL N K ++ FI M +DEK+ A+ + G L + + D++ K +N+DER N AQ KLK+ + L + L D D+L + + EK+ + + + K+ S + +A + E+ A + +++L D P + I ++ L + W EL K EEK Q L NR++L+ +S M +W +E ++ +D+P +T++ ++K E+ K + ++ L + L++ +PD+ + V+ + L PL+ + +K A QF +D DDE W++E++ L +K +L +LQ + + NEI N ++ + Q +IDE H + +L+ + L E ++ + L +FL D E +W+SE+EL +M KD+ + I+K + L+ +I + I +E + + +E + L+ + E++ + L+ ++ + +L Q WI ++ +A S ++G+D + +L++RF F+ +T IGS +V AN D LI H A +I++WKD +NE W +LLEL+DTR Q+L+++ LH++Y D + L I EK +M +DLG+D SV L RK +N+ KD+ + + + L Y DK + + E++ A+R LR + + R ++ +D F++MVR+LL W++EV +M + +P+DVSG+ELL+ NH+SLK E+D++EENF+ C++LGR LL KH S EI+ K ++T +R + ++W + ++L L++EVYQ+ARDAA AE+W+ +QE YL ++ G L+ET+ L+KK F+K+ QEE+F L++LTT E++
Sbjct: 5 DGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERVQAVVAVAGELEAENYHDQAKINERKENVLQLWNYLFQLLLARRVRLELSMAIQKIFHDMLLTLDLMDDIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRF-RNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAES-LPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMG-DRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR-----------HQDFITTMDANDEKIRAVGMF-GDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQP----GDLTTVNVAMQKQHLIETEMIKKAQHIDQLMEMEPQLEELHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVL----AKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQ-DERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDLSKERRKRLEETLELYALHREIDDLLQ----WIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAM--PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELK 2075 HSP 2 Score: 88.9669 bits (219), Expect = 4.859e-17 Identity = 56/191 (29.32%), Postives = 84/191 (43.98%), Query Frame = 1
Query: 6718 SKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFS 7290
+KR P+++ P + + A A +G L RKH +E+ ++KA+NR+W LY +L Q+ ++F+KD +H E E P+ L A DY K+ V +R GAEYLFQ S DM RW+ + A+ + S S +LP + K FFS
Sbjct: 2085 AKRRGPAHIGSPSRSTPAAETSFGAQDDGAKQGEA------FEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDES----VHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASR------------SQTLPAEGSATKKKGGFFS 2253
BLAST of Spectrin beta chain vs. Ensembl Celegans
Match: unc-70 (Spectrin beta chain [Source:UniProtKB/TrEMBL;Acc:E0AHA7]) HSP 1 Score: 1278.08 bits (3306), Expect = 0.000e+0 Identity = 771/2125 (36.28%), Postives = 1237/2125 (58.21%), Query Frame = 1
Query: 91 ICVPYLNGNYCDSLSSDYQNALSDEDEV-QYANVTSKVFERS-------RIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKD--IQSLINNFNTSKSNLLSLNEIVNENEIFIDKM-LSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPDEYKGIVK-------DVEDNFNSLKIICAEKKTE----ISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIR 6399
+ P + +LSS N L+DE+ A V+ V + R + L DERE VQKKTFTKW+NS L+ V+ K++DLY+D+RDGK LL LL +LS E +PKPT G+MRIHCLENV+K L FL NQ VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI F++ + +SAK+ALLLWCQMKTAGYP+VN++NF+ SWR GL F ALIHKHRPDL+D+ + +++ + NL AFD AEN LG+ LD EDVNV PDE+S+ITYV +YYHYFN LK ++ KR+ K++N+++E+++MI Y++L S LLEWI I+LLN R F N++ G+Q+Q+ FN YRT EKP KF EK +LEVLLFT++S + + + P E ++ IN AW L AE+ RE L++EL+RQEKL LA +FN+KA +RE+W+T+N L+ + + GN+L +V AA KKHEAIETDI+AYEE + + ++ LE E Y+D I K VL LW L Q L RR L+ + + + ++ ++ I ++ ++ G HLM+VE+LL+ H L+ESDI I +R+ I++A R+ + D S I E+ + K + ELLD +RK L+ + + QF D + E IKE ++++ D G D+ +V LL KHK E L L+ + GK L D S G + I + +I++ L + + SRK +L ++YYQ+ +D DD + ++ + R+ + +G ++L++K+ + ++N+ +I+ + +A+S L +H + ++LD K+ +L +++ +++L+DAL++Y+L +D+DSV SWI EK K L +P DIEE+E++KHRF+ E ++ + KV +VN+L+ L+ +PN I++ Q+ LN W ++ D+VD KR+EL + F +DCQ+T+ WI +K +++E D L DL VM+ QRR++ M+RD+ AI+AK+D L + D+I R + A+ I + +HQ W+IL + +R+ ++ L D+ RF++ LD F WL Q ++AS+ P+S +EAE+L+N++ + R+E+ + ++ +G D + +Q Q++ L+ R+ + + W+ L + + ++ L + L MF DA+Q E +L+ QE YL KD QSL N K ++ FI M +DEK+ A+ + G L + + D++ K +N+DER N AQ KLK+ + L + L D D+L + + EK+ + + + K+ S + +A + E+ A + +++L D P + I ++ L + W EL K EEK Q L NR++L+ +S M +W +E ++ +D+P +T++ ++K E+ K + ++ L + L++ +PD+ + V+ + L PL+ + +K A QF +D DDE W++E++ L +K +L +LQ + + NEI N ++ + Q +IDE H + +L+ + L E ++ + L +FL D E +W+SE+EL +M KD+ + I+K + L+ +I + I +E + + +E + L+ + E++ + L+ ++ + +L Q WI ++ +A S ++G+D + +L++RF F+ +T IGS +V AN D LI H A +I++WKD +NE W +LLEL+DTR Q+L+++ LH++Y D + L I EK +M +DLG+D SV L RK +N+ KD+ + + + L Y DK + + E++ A+R LR + + R ++ +D F++MVR+LL W++EV +M + +P+DVSG+ELL+ NH+SLK E+D++EENF+ C++LGR LL KH S EI+ K ++T +R + ++W + ++L L++EVYQ+ARDAA AE+W+ +QE YL ++ G L+ET+ L+KK F+K+ QEE+F L++LTT E++
Sbjct: 51 VASPGIYPGSAGALSS-LSNGLADENRSPTSAEVSDSVCGQKSINSVDLRFRGLRDERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERVQAVVAVAGELEAENYHDQAKINERKENVLQLWNYLFQLLLARRVRLELSMAIQKIFHDMLLTLDLMDDIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRF-RNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAES-LPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMG-DRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR-----------HQDFITTMDANDEKIRAVGMF-GDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQP----GDLTTVNVAMQKQHLIETEMIKKAQHIDQLMEMEPQLEELHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVL----AKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQ-DERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDLSKERRKRLEETLELYALHREIDDLLQ----WIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP--DDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELK 2144 HSP 2 Score: 88.5817 bits (218), Expect = 6.134e-17 Identity = 56/191 (29.32%), Postives = 84/191 (43.98%), Query Frame = 1
Query: 6718 SKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFS 7290
+KR P+++ P + + A A +G L RKH +E+ ++KA+NR+W LY +L Q+ ++F+KD +H E E P+ L A DY K+ V +R GAEYLFQ S DM RW+ + A+ + S S +LP + K FFS
Sbjct: 2154 AKRRGPAHIGSPSRSTPAAETSFGAQDDGAKQGEA------FEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDES----VHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASR------------SQTLPAEGSATKKKGGFFS 2322
BLAST of Spectrin beta chain vs. Ensembl Celegans
Match: sma-1 (SMAll [Source:UniProtKB/TrEMBL;Acc:G5EFW3]) HSP 1 Score: 507.679 bits (1306), Expect = 1.272e-144 Identity = 304/812 (37.44%), Postives = 466/812 (57.39%), Query Frame = 1
Query: 157 SDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQF-DEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEK 2589
+D+DE N + FERSRI+ L DER ++QKKTFTKW NS L +++I DL+ D+ DG L+ LLE++S + + KP RGRMR+ +EN++K L FL +K+ LEN+GA DI+D N RL LGLIWTIILRFQ+ I DE+ K AKDALLLWCQ KTAGYP+V I NFT SWR GL F ALIH HRPDL+DF+ N N++++NL+ AFD+AE L I LLD EDV+V PDE+S+ITYV+ YYH+F K +R+ ++ +++ E M Y+ + S+LL WIR TI+ L R+F NS+ G++++ FN +RT EKP K+ EK +LE L FTI++ + K Y PP+ + I SAW +L+ AE R+ A+ EL RQEKL LAQ+F+KKA LR+SW+ +L++ G + V LKK +AI TDI A E+ LT + + L E Y++ + + +++D W +LL L +R+ L + + +L+ + + + + R + GKHL+ VE+LL H+L+++ I + L KL AN Y++ ++ F +++ K + ++ L++ R+ L+ + ++QF+ D E W+ E + D+S+V + +K E+E+ + + + G+ LV + +E I + + + WE L + ++ L E QY D ++AE WI E L LG E L++++ + E + Y+ +I ++ + QS L S T ++ + E+
Sbjct: 25 TDQDEF---NNETLYFERSRIRTLQDERVHIQKKTFTKWCNSFLNRASLEIVDLFEDVGDGIMLMKLLEIISGDKLGKPNRGRMRVQKVENLNKVLDFLKKKKIQLENIGAEDILDRNERLILGLIWTIILRFQIDTIVIEDEEERGERKHAKDALLLWCQRKTAGYPNVRIENFTTSWRNGLAFNALIHSHRPDLVDFNRLNPNEHVDNLNHAFDVAEKKLEIARLLDAEDVDVTRPDEKSIITYVSLYYHHFAKQKTEMTGARRIANIVGKLMVSETMEDDYEHIASELLNWIRVTIKTLESRRFPNSLNGMREEHAKFNQFRTSEKPPKYKEKGELEALFFTIQTKRKAMSRKQYQPPQGLFMHDIESAWAQLDYAENERQVAIIAELQRQEKLEQLAQRFHKKAKLRDSWLRSVQVVLEEMEHGRSASQVEKTLKKQQAISTDILAREDRFKMLTAMCNELCTEKYHESDKVRGMEREIIDRWTQLLTLLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRDVGKHLIGVEDLLGKHDLLDAQINAHGSLLSKLSQSANNYIRHKEEQF---------DVLQRKLDEVTAQYNTLVELCRSRRLGLERARSLFQFVQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTLLYKNVEMEMQTHWARSKGMIAGGERLVQ-NGQSKEDIQRRLTQMNHRWERLRVAVDALGNWLSEARHAQQYFQDANEAESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKSDISRL-EEMQSQLANSAFHTATTSQSVQETEE 822 HSP 2 Score: 225.713 bits (574), Expect = 2.266e-58 Identity = 444/2160 (20.56%), Postives = 894/2160 (41.39%), Query Frame = 1
Query: 973 VLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFT---IKSNQFVSRLKVYNPPEEFSLSTIN------SAWDELNTAEYGRET--ALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDL-WKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRS---IN--QRLEKLISEANRYVQFCDQ---DFRSNINSGNKAMIKEKRNST-IKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEG--KTLVDISPVGQEFIAAKNNDIQN--LWEA--------LVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDE----FKRLFDLKFLGDKMSFTEILIR-KNQQNMEI-VENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFV-----RLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKII-AEQFLQ---DCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVIN---SKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-PDEYKGIV------KDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVN--DLGK-DPKSV-SLLQR------KLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNE-NLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTME-----IRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALS--PVPQMKQSKRPQ------PSNM--------SKPVHNLSVSTDMLSASPKPATTRTIPPEE---------VLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAI 7155
LED + Y + L + I +R+ +F+ +++ + F+ +F +KV FT +N + R NPP F+ + +AW+ L R++ A+ +EL R F++ E W+ D M + + LG ++ V + + HEA++ +I+ + L L + ++ L++ I + + L+ W++L +R++ L ++T GK V +LL +L SDI+S IN Q+ E L +E +R D +F +N G K + + S IK+ LL S +R + L F+ A + +E I+ + +G +++ L V ++E +KR+ K + + + E + A++ + +N +W++ L E+R L + + SD E WIDE ++ DL + +S E + R + Q +E V + ++QI + L ++ + +A + D + K+ L L +A + R ++V +WI EK+ + D+E +L R + S+ + + +N L E LV G + + Q +LN W + + R ELL+ F D + T E I EK+ ++S D+ G+D SV R+ + ++RD+ AI K+ +IL + + L + + WE L + R+ L +++++ + W Q++ +M S P+ + A K++ +++ ++ E+ ++L + G+ + + + V R+QN + Q W+ ++ L+K L+ +++ ++A Q E+ L+ +E + + + ++ ++ + F + + + + + K L+ N Y+ + + + + R + + R + L++ HE ++ +L + K+Q+ + S L++ + S L + A + E+ + + ++G+Q D +++ L L S W EL K Q L + + + KWL +EG++ +DD I S +KKLD+ E+ + + + + L+ Q A + QV+ GL P++ I + ++ A+ F Q +++++W+++++ L + E+ +L LQ +H +++ E+ R ++ Q + MI + H + +++L L E +++L + E+ + +E W+ E+ M L ++ +D +R+ L+ E++ + +I+ KK L E+ + + +E F L CA ++T+I Y ++ W+ E+ + A ++D G+DL+ C + ++F E G +V + ++L++ HP+ SI+ + +W + E+ + R Q L A +HR+ ++ +L +Q+K+++ + DL + D SV + LQR +K EK + +L + A + N+ P E + ++L D + +K LE KL +++ ++ RE++ W++ + M PRDV+ E L+ H +EM ++ GR ++++ H+ S EI+ K + +L + W + + ++V +W ++A ++W+ + L ++ + +++ L+ F F Q EK + +KRLT +E +RSK+++ R + E Q + ++ E I+ + Q+ RR + EI S++RP P S +P+ ++ R + P + S V L +M + +P T RT + + MKG RK ++ ++A+ R+W + Y +L + FFKDE+ F E P+ + +Y KR FR+ ++G+E++F M WV I
Sbjct: 1767 ALEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFD---------EFKQKVKNGSERFTSCETAANAILRR----NPP--FARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEELHR----------FHRDVDEFEQWMADKMANMPR-DLGRDVKHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERLKKTYPGGNAEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTF----------------------NGK----VRDLLAWTDLTISDIQSDLHINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMITAQHYASEEIKNKTHLLKSALER--LRSEWALRNGFLSQAVQWHAFQREAKQIIAS--IGSKRTTLRSLAVGGSVADVESQTKRLDTFEKALSTLDERTATLDHTANELMKARHMESKNISMWQSNVHEELKLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRKAQDLS--SESISIDEKMKRLQTHQALEAEVTANKPVVDQILQRGNQL--KNLHRNPKIANRCDELSYKWNQLSGACADQSLALEEARDLLRFKQLVENVLAWINEKEVLVSTADMGKDMEHCRLLLERLDGTRSDSIVDEQTLDEINRLGEKLVKQGRSSRDQVQKEQQHLNEKWRLLLGQLAHYRTELLAAMEVHTFNRDVEDTDERIHEKVAAMKS-DDYGKDFASVELLVRKQSALERDMSAIHQKLIAHDKDAQKILEKRPPLRETVLDSLKKLEESWEQLSKAAELRNEKLNRSFKLYKYLDDVKKVEQWANQVRNKMTSHQTPKDSNGARKILEQHHERKAEIDGRSEELRLLHEEGQALNQEQPEHKAEVQRAHKRVQNSEHQLRQTWE-------SEKGTLQKLLEWMLWCDEAVQCEQWLSDKETQVARGELGDTTD---------AVEMLIKGHSAFEETVRKQSEKIDALTKNADALVSGGNNYRADIVTRSEEVTARHALLLKSMEKRGHMLEDSKKYHEFIRQCGELIIWITAKLQLAYDESFLDHTNLRSKLQKHMAFDSELVENEKRLSTVERQGEQLVTDNHFMSEQVKAQLVELRSGWDELRTKSALKTQRLREAFELHSLQRKVEDIEKWLDKVEGELSSDDHG----RDILSTELLIKKLDTLQTEIAGRSDAVVEMMKKARELRVQGSAAADDCLKQAEQVEARYSGLDEPVQ----IRRENLVDAQAFFQWVKAAEEDLEWLSDRMML----ASSGESGDSLQSALSLQKKHATLEKELDTRQSAMNDTEQRGKDMIRQRHFASTHIQKILDRLSSAMLTLKESCGLRRDLLQEAIDAHEYYTEETEAEQWLREQ----MPLAMSQEMGRDQAGAESHLRRLTVLDKEVELFKNEIDRLKKRADGLLAREHHDAMSIAAKQRKLEALFGDLCRECARRRTQIVDASKYHKFVRQADDLSDWLREKERSASAEDYGQDLEDCQQIIEQFESTVRELAAAGE-RVAAVQRAQEDLLRSGHPYGASITAKGADVQRLWTHVNEVANERKQALNGARQVHRFDQEADQILNWLQDKEATGVAMEQEDLSRADLASVKAQLQRHDEFMHGMKAVEKQVAEL---CHEAERLWNSF-PDTRHHLEVRRLDMEEQLKDILEAAKKHLE--KLRHMQ--SLQSYFQEYREMMQWMKNMQSTMTSEQLPRDVASCESLVRRHDEYNLEMQGRKPFVDDFARQGRRMIQSSHVLSQEIQEKVDILEKSWAMLCEIWKDRAELYEENMDVQKWKQNAEQLDSWLEERAGLLGDDWRMVDSVEMAETHLRDFDDFLVTLEAQSEKCDMVKRLTLVEQNFSRLRSKEIDRAR-----------------IAEDDQKRRDTIKIVEKGNIL---ANRRQERERR---------KTQEI-------------SLLRPSPSGEEFSTHTMPRKERKDRAKTTADLAPGAIQIGDILASSSTVAPLQSGVEM-TKTPSFNTRRTQSIRKGSRWEDMGAIDMKGFFDRKQCQQSGGKRATIRSWKNYYGILCGQLLCFFKDEQQFLEN----VAAAPPVYIYGAQCEQYPEYAKRKNSFRLLLQDGSEFIFSCPDERQMLEWVAKI 3777 HSP 3 Score: 131.339 bits (329), Expect = 8.287e-30 Identity = 337/1717 (19.63%), Postives = 720/1717 (41.93%), Query Frame = 1
Query: 1390 SWITDNMELLQKQSLGNNLPTVLA-ALKKHEAIETDIYAYEENLIGLTKISDNL------EEEIYNDIISIINTKNKVL--DLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILR-HNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNW----LGQMQTEMASQNIPES---QSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNL--LSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTL-ILENNLYKDR-MQNKCQNLDERWKKNT-----LAAQN---RKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTD-----SCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEP-------------DGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQ--QNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIR--NRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL---PDEYKGIV----KDVEDNFNSLKIIC-AEKKTEISL--FVIYCDTYELYQNIEAWIVER-TKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEK------KSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQK 6336
W+ + +L+ P+ + L KHEA E +I A E + + D L E I+ +N + L +W K L+ R+ D L + ++ + T + +K + G L V++LL+ H ++E ++ +L + + + D + ++ I ++ + + +RK L S L Q + D E QWI E I ++ D G L+ +++K + E E++ ++ L++ L+ I AK+++++ W L R+ + + QY+ D + E W++E + + G+ L+ K++ E + YR +E++ + L+ + + K+ D + +++ L +A + L DA+ +Y + +S + I E + + ++D E L+ L+ +F+ F+ ++ +E+ + ++ P + +V Q+ L +WN + + ++++ +L F D + +W+ +K+ + +LG D++ V + + ++I + ++ LV + + + + + +A+ I + + QEWE L+ DR L D+H F K+ D W + +Q+++ ++ ++ Q+E +L ++ +++ E A + E+ I SE+ K++ L++ +E + +W + N F A Q ++ + +I + + ++ L L++ V + E ++ + EK L+ + ++ TL N L K R M++K ++ W+ N L Q+ R LK+ L D+ ++ + EK + + L+++S L +ALE E+ A +P+++++ +RG Q H +I + D L+ W +LS A ++ L F++ ++++ W+ E + D DG+RS SI ++ + LD N +L+KQ + D+ K +Q + + G ++L A + F +D +D + ++EK+ ++ + K ++ L++ Q R S I + + D ++AQ+++++ R V+D++ +L+++ E L++ E L+ + ++L DV +V W ++ + M KD R+++ + + EI ++ + +L E+K V K V+++ + L+ +EK T L ++++CD E Q E W+ ++ T++AR + G D +L F ET + S K++ K D L+ G + + I + + A LL+ ++ R +L+ + H + L+ I K +S ++ N K K ++ ++N EK L ++ +T N + K A L++ R D R+ + L+ ++L E + H+ V ++ W+++V ++ RD+ ELL+ +L+ E+ + + + R L + + + +++ + L + ++L +QW + A W+ + ++ G +L L+L KK +K
Sbjct: 1361 GWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLVSKKHYESPNVEKIVRQVNAQWGDLKKQVWNKGLRL----RQAADQKGLDRILEDAHAKLDEMQTALNSK----DQGLDLRSVKDLLQKHAVLEQEMGLYGNKLSDIENRGKKMA--VDGHYDAD-------RIHSTVGQLLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSASSQIKAKSSELETAWSELKKLLRLRRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTTYRQWLEKLEVKCVELVESNRPHVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEFKQKVKNGSERFTSCETAANAILRRNPPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEELHRFHRDVDEFEQWMADKMANMPR--DLGRDVKHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERLKKTYPGGNAEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLHINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKM--ITAQHYASEEIKNKTHLLKSALERLRSEWALRNG-----------------FLSQA--------VQWHAFQREAKQIIASIGSKRTTLRSLAVGGSVADVESQTKRLDTFEKALSTLDERTATLDHTANELMKARHMESKNISM---WQSNVHEELKLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRKAQDLSSESISIDEKMKRLQTHQALEAEVTANKPVVDQILQRGNQLKN--LHRNPKIANRCDELSYKWNQLSGACADQSLALEEARDLLRFKQLVENVLAWINEKEVLVSTADMGKDMEHCRLLLERLDGTRS--DSIVDE-QTLDEINRLG-------------EKLVKQGRSSRDQVQKEQQHLNEKWRLLLGQLAHYRTELLAAME---VHTFNRDVEDTDERIHEKVAAMKSDDYGKDFASVELLVRKQSALERDMSA---IHQKLIAHD---KDAQKILEKRPPLRETVLDSLKKLEESWEQLSKAAELRNEKLNRSFKLYKYLDDVKKVEQWANQVR-NKMTSHQTPKDSNGARKILEQHHERKAEIDGRSEELRLLHEEGQALNQEQPEHKAEVQRAHKRVQNSEHQLRQTWESEKGTLQKLLEWMLWCD--EAVQ-CEQWLSDKETQVARG-ELGDTTDAVEMLIKGHSAF-EETVRKQSEKIDALTKNADALVSGGNNYRADIVTRSEEVTARHALLLKSMEKRGHMLEDSKKYHEFIRQCGELIIWITAKLQLAYDESFLDHTNLRSKLQKHMAFDSELVEN-EKRLSTVERQGEQLVT-DNHFMSEQVK---AQLVELRSGW-DELRT-KSALKTQRLR--EAFELHSLQRKVEDIEKWLDKVEGELSSDDHGRDILSTELLIKKLDTLQTEIAGRSDAVVEMMKKARELRVQGSAAADDCLKQAEQVEARYSGLDEPVQIRRENLVDAQAFFQWVKAAEEDLEWLSDRMMLASSGESGDSLQSALSLQKKHATLEK 2986 HSP 4 Score: 123.635 bits (309), Expect = 1.639e-27 Identity = 131/615 (21.30%), Postives = 267/615 (43.41%), Query Frame = 1
Query: 4552 GLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYY------------------PKIEEFKKSCVSLPDEYKGIVKDVEDNFNSLK-IICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKA 6339
+ P + + ++ + Q + D D E+ W+ EK + + + TL + + + + ++ E+ ++D ++ +A +I +H + + ++L+ L + + + ++ + Q++L D +EV SW++EK + + D+ R+++ K + L ++ Y P +E F+K L E+ + K ED N+L+ +C L+ ++ +L Q+IE E ++A S++ +D + L+ +F F + K GS + + +++ PFA + ++ + W L E I+ R L A +LHR++ D + + +K ++M DLG+D K V L + + +K++ + + + L Y + ++Q L + L+ +DRK D H F VR+LL W + ++ D+ E L H L EMD++E F+ +N G ++ +H S EIK+K + + L +W LS V+ + + R+A A + S+ + L + +G ++ + + K+ F+KA
Sbjct: 1544 AMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPI----ASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSASSQIKAKSSELETAWSELKKLLRLRRAVVDWGVKEQQYLFDAAEVESWMNEKR-NALASEDYGNDEDAARKLLSKHRALCEDMTTYRQWLEKLEVKCVELVESNRPHVERFQKRQDELVREFDALSKLAEDRRNALEDAVC--------LYEYMRESADLGQSIE----ENLRVAMSEEFAEDYEHLKELQSKFDEFKQKV-KNGSERFTSCETAANAILRRNPPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEELHRFHRDVDEFEQWMADKMANMP--RDLGRDVKHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERLKKTYPGGNAEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLHINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMITAQHYASEEIKNKTHLLKSALERLRSEWALRNGFLSQAVQWHAFQREAKQIIASIGSKRTTLRSLAVGGSVADVESQTKRLDTFEKA 2138 HSP 5 Score: 101.293 bits (251), Expect = 1.060e-20 Identity = 147/684 (21.49%), Postives = 295/684 (43.13%), Query Frame = 1
Query: 1357 QKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRI----DNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEI----LKHSHLVWQFIVDASLEEQWIK--ELVDIMNNPDLGYDLSSVDRLLRKHKVFELEL---SSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLD-ALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDEL---LSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEM 3357
Q FN+++ ++ + L+ +LG+++ +V LK+H +E + A E L ++ +D++ + + D I + VL + + + +R++ L+ L+ + E EV + + K ++ D+ + L HE E++I + R++++ SE + V + + S N I + N+ D +K++ L+ Q +D LE+ K E+ +N+ D G DL SV LL+KH V E E+ +K +EN+ GK + + I + + + A+ + RK L E ++Q V D D WI E K + + G ++ +++K +Q V + I+++ QA L+ + K +E + +L + +++ ++D + + L D+ V SW+ EK+ L + +D + L + ++T + + + LV + P+ + QD L ++ ++ + + +R+ L + Y Y D Q+IE E +++ S +E ED E + + Q + + ++ + + + ILR N A+D+ + + + W L + I RDS LA ++HRF + +D+F W+ M
Sbjct: 1244 QLFNRESERIDAATKGHEAFLEFDNLGDSVESVENLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEV---VGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLVS------KKHYESPNVEKIVRQVNAQWGDL---------KKQVWNKGLRLRQAADQKGLDRILEDAHAKLDEMQTALNSKDQGLDLRSVKDLLQKHAVLEQEMGLYGNKLSDIENR---GKKMAVDGHYDADRIHSTVGQLLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSASSQIKAKSSELETAWSELKKLL-RLRRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTTYRQWLEKLEVKCVELVESNRPHVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYEYMRESADLGQSIE---ENLRVAMS-EEFAEDYEHLKELQSKFDEFKQKVKNGSERFTSCETAANAILRRNPPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEELHRFHRDVDEFEQWMADKMANM 1901
BLAST of Spectrin beta chain vs. Ensembl Fly
Match: beta-Spec (gene:FBgn0250788 transcript:FBtr0074454) HSP 1 Score: 1299.26 bits (3361), Expect = 0.000e+0 Identity = 780/2103 (37.09%), Postives = 1245/2103 (59.20%), Query Frame = 1
Query: 148 NALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLK--SEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQL---ETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKI-------EEFKKSCVSLPDEYKGIVKDVEDNFNSLKIICAEKKTEIS----LFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKK 6408
N DE E N +S++FERSRIKALA+ERE+VQKKTFTKW+NS L V +I DLYVD+RDGK L+ LLE+LS E +PKPT+G+MRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN L LGLIWTIILRFQ+QDI +E + KSAKDALLLWCQMKTAGY +VN+RNFT SWR GL F A+IHKHRPDL+ F ++ + I+NL+ AFD+AE+ LG+ LLD EDV V PDE+S+ITYV +YYHYF+ LK +V KR+ K++ +E+++M+ Y++ S LL+WI TI+ L R+F NS+ G+Q Q+ F+ YRT EKP KFVEK +LEVLLFT++S + K Y P E +S IN AW+ L AE+ RE ALR+EL+RQEKL LA +F++KA++RE+W+++N L+ + + G +L V AA KKHEAIETDI+AYEE + + + D LE E Y+D+ I+ K+ V+ LW LL+ L RR L+ LQ+ E + + I D+YGKHLM VE+LL+ H L+E+DI + +R++ ++ + +++ D + + +I + + EL+ +R+ L+ S +WQF D + EE WIKE I++ ++G+DL++V+ +L KHK E E++S L+N G L+ G + I + +I N W+ L+D T+ R+ +L ++Y+Q +D DD + W+ + R+ + +G + + L++K++ + ++NY + I+ + QA+S L + + V K+L+ I+ +Y++L ++A +++LLDAL++Y+L++++D V WI EK K L P DIE++E++KHRFE F+ E+ A +V VN L+ L+ +PN I+ Q++LN W+ + + ++K D+L S + F+++C++TI WI +K +++ D L DL VM QRR++ M RD+ AI+AK+ L + + I + AK I ++ + WE L Q++++RDS L D+HRF++ LD F WL + QT++AS++ P S EAEKL+N++ S R+E+ + + M+ G+ S D Q++ L+ R+ ++ W+ L+ + E ++ L + L +F DARQ E +L+ QE +L KD + NL + +E F+ M +++ + +L+ TL+ +++ D++ + +N+ R N A ++ KLK QV LHE LQD+++L + + EK + S + K+ S + +A E EI A + + E K ++ S + P FK I L L + +L +EK L NRE L +++ + ++ ++E QIV+ D + + +TS+ ++K ++ K + +E + +E L++ P++ K E + +T V + + PL + +K A QF +D +DE W++EK+ + + + +L L+ +++S+ EI N +++++ +++IDE H ++ L + + L + +E + L VQ++ D E SW+SE+EL +M + KD+ + +++K +NLE +++Y I +F +S D ++ + LK + E++ ++ LF++ + ++E WI +R +A S + G+D D TLL +RF F+ +T +G +V + N D LIQ H + +I+ WKD +NE W DLLELI+TR Q+L ++ +LH+++ D + +L I EK+ V ++LG+D SVS LQRK NF +DL+ L S + S L Y DK + + QE++ A+ +L+ + + RK + D F +MVR L+ W+E++ QM KPRDVSG+ELL+ NH+SLK E+D++E+NF C++LG+ LL H S +IK + +++ R+ L ++W ++L L++EVYQ+ARDAA AEAW+I+QE YL + LG T+DE L+KK F+K+ QEE+F L+RLTT E++ K
Sbjct: 18 NEYIDEYEYDGGNSSSRLFERSRIKALAEERESVQKKTFTKWVNSHLCRVNCRIADLYVDMRDGKHLIKLLEVLSGERLPKPTKGKMRIHCLENVDKALQFLREQRVHLENIGSHDIVDGNASLNLGLIWTIILRFQIQDITIEEVDNKETKSAKDALLLWCQMKTAGYHNVNVRNFTTSWRDGLAFNAIIHKHRPDLVQFEKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDVFVEHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMENDKMVHDYENFTSDLLKWIETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQSKMRANNQKPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFL----SDDPESYKPCDPEIIVSRVQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDALHKQAES-LKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKD---------DTPVNLEQAENQLKRHEAFLTTMEANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRALDQHEKLKNQVKLHEFLQDLEELAEWVQEKYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKERLFEAEKSAQELSKEKPEFKDVIEPKLKELAKQFDDLEVHTKEKGAMLFDANREVLVQQTCDDIDSYITDLEKQIVSGD----TANDLTSVNILMQKQQVIQTQMAVKARQVEEIDKQTEYLQKTVPEE--KIEPIVVKKTAVLERFEKIKAPLLERQKALEKKKEAFQFCRDVEDEKLWIDEKLPV----ANSPDYGNSLFNVHVLKKKNQSLATEIDNHEPRINAICNNGRKLIDEGHEDAKKFEALISDLTQKWQELKDAIENRRKHLLESEKVQQYFFDAQEAESWMSEQELYMM-VEDRGKDEISAQNLMKKHENLEQSVEDYANTIRQLGEVARQFSGDDISSGDAVAVKQSQLDKLYAGLKDLAGERRARLNEALQLFMLSREV----DDLEQWITDREVVAGSQELGQDFDHVTLLSERFNEFARDTEAVGGERVAKVNGIADNLIQAGHSDSATIAEWKDNLNESWQDLLELIETRTQMLAASRELHKFFHDCKDVLGRILEKQHG--VSDELGRDAGSVSTLQRKHYNFLQDLITLYSQVQQIQEESAKLQDAYAGDKAKEITNREQEVLHAWDNLQAMCDARKQKLADTGDLFRFFNMVRILMIWMEDLVRQMNTSEKPRDVSGVELLMNNHQSLKAEIDTREDNFGACISLGKELLTRNHYASADIKDRLMTLSNSRNALLRRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLLSSELGHTIDEVENLIKKHEAFEKSAAAQEERFSALERLTTFELKEMK 2089 HSP 2 Score: 131.724 bits (330), Expect = 6.665e-30 Identity = 140/618 (22.65%), Postives = 280/618 (45.31%), Query Frame = 1
Query: 4612 QFLQDCDDEIDWMNEKIDLIRNR--SKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVIN---SKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLP---DEYKGIVKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ---NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELID-AFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRS-PE---IKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNT 6417
QF D DE +W+ EK ++ + T+ +L +HK++++EI + ++ ++ + +I E H + D + ++ ++L + + + L N + + D +V +W+ LD + +V + +D+ ++ +++K +++ E+KNY I+ K SL E + K +E N K + K + Y+L +E WI E+TK+ + GKD++ +++ RF F E N +S+V N+ +L+ +HP + I ++ +N+ W+ L E + ++ LKSA + +Y + + + I++KK + + L D V LQR+L ++DL + + +++ +N++ + + EA +I++R I+ + L ++L++R E D H FL + W+ + + P + E LL H+S++ E+D+ E++ + G L P+ ++ + + D + L Q W N LS ++ + RDA E + QE +L+ ++ + L++ LK+ F LTTME K+NT
Sbjct: 639 QFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLS------KHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWM----LDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDALHKQAESLKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMN-ANASRVAVVNQLARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPE--EAKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRHEAF----------------LTTMEANDDKINT 1227 HSP 3 Score: 89.7373 bits (221), Expect = 3.736e-17 Identity = 47/174 (27.01%), Postives = 85/174 (48.85%), Query Frame = 1
Query: 6784 LSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFSSIRLK 7305
+ AS + P +G + RKH+W++ +KASNR+W +Y+ R++F+KD++ +K P+ ++ E L A DY K+ V RV+ NGA +L Q +M++WV ++ + S +T + S +LP +Q + +R F +++ K
Sbjct: 2131 VGASHDDSERGGTPGAGEGHEGYVTRKHEWDSTTKKASNRSWDKVYMAAKAGRISFYKDQKGYKSNPELTFRGEPSYDLQNAAIEIASDYTKKKHVLRVKLANGALFLLQAHDDTEMSQWVTSLKAQS-------------DSTAVAASRSQTLPATSQKDEPKRRSFFTLKKK 2291
BLAST of Spectrin beta chain vs. Ensembl Fly
Match: beta-Spec (gene:FBgn0250788 transcript:FBtr0334404) HSP 1 Score: 1298.88 bits (3360), Expect = 0.000e+0 Identity = 780/2103 (37.09%), Postives = 1245/2103 (59.20%), Query Frame = 1
Query: 148 NALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLK--SEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQL---ETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKI-------EEFKKSCVSLPDEYKGIVKDVEDNFNSLKIICAEKKTEIS----LFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKK 6408
N DE E N +S++FERSRIKALA+ERE+VQKKTFTKW+NS L V +I DLYVD+RDGK L+ LLE+LS E +PKPT+G+MRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN L LGLIWTIILRFQ+QDI +E + KSAKDALLLWCQMKTAGY +VN+RNFT SWR GL F A+IHKHRPDL+ F ++ + I+NL+ AFD+AE+ LG+ LLD EDV V PDE+S+ITYV +YYHYF+ LK +V KR+ K++ +E+++M+ Y++ S LL+WI TI+ L R+F NS+ G+Q Q+ F+ YRT EKP KFVEK +LEVLLFT++S + K Y P E +S IN AW+ L AE+ RE ALR+EL+RQEKL LA +F++KA++RE+W+++N L+ + + G +L V AA KKHEAIETDI+AYEE + + + D LE E Y+D+ I+ K+ V+ LW LL+ L RR L+ LQ+ E + + I D+YGKHLM VE+LL+ H L+E+DI + +R++ ++ + +++ D + + +I + + EL+ +R+ L+ S +WQF D + EE WIKE I++ ++G+DL++V+ +L KHK E E++S L+N G L+ G + I + +I N W+ L+D T+ R+ +L ++Y+Q +D DD + W+ + R+ + +G + + L++K++ + ++NY + I+ + QA+S L + + V K+L+ I+ +Y++L ++A +++LLDAL++Y+L++++D V WI EK K L P DIE++E++KHRFE F+ E+ A +V VN L+ L+ +PN I+ Q++LN W+ + + ++K D+L S + F+++C++TI WI +K +++ D L DL VM QRR++ M RD+ AI+AK+ L + + I + AK I ++ + WE L Q++++RDS L D+HRF++ LD F WL + QT++AS++ P S EAEKL+N++ S R+E+ + + M+ G+ S D Q++ L+ R+ ++ W+ L+ + E ++ L + L +F DARQ E +L+ QE +L KD + NL + +E F+ M +++ + +L+ TL+ +++ D++ + +N+ R N A ++ KLK QV LHE LQD+++L + + EK + S + K+ S + +A E EI A + + E K ++ S + P FK I L L + +L +EK L NRE L +++ + ++ ++E QIV+ D + + +TS+ ++K ++ K + +E + +E L++ P++ K E + +T V + + PL + +K A QF +D +DE W++EK+ + + + +L L+ +++S+ EI N +++++ +++IDE H ++ L + + L + +E + L VQ++ D E SW+SE+EL +M + KD+ + +++K +NLE +++Y I +F +S D ++ + LK + E++ ++ LF++ + ++E WI +R +A S + G+D D TLL +RF F+ +T +G +V + N D LIQ H + +I+ WKD +NE W DLLELI+TR Q+L ++ +LH+++ D + +L I EK+ V ++LG+D SVS LQRK NF +DL+ L S + S L Y DK + + QE++ A+ +L+ + + RK + D F +MVR L+ W+E++ QM KPRDVSG+ELL+ NH+SLK E+D++E+NF C++LG+ LL H S +IK + +++ R+ L ++W ++L L++EVYQ+ARDAA AEAW+I+QE YL + LG T+DE L+KK F+K+ QEE+F L+RLTT E++ K
Sbjct: 18 NEYIDEYEYDGGNSSSRLFERSRIKALAEERESVQKKTFTKWVNSHLCRVNCRIADLYVDMRDGKHLIKLLEVLSGERLPKPTKGKMRIHCLENVDKALQFLREQRVHLENIGSHDIVDGNASLNLGLIWTIILRFQIQDITIEEVDNKETKSAKDALLLWCQMKTAGYHNVNVRNFTTSWRDGLAFNAIIHKHRPDLVQFEKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDVFVEHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMENDKMVHDYENFTSDLLKWIETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQSKMRANNQKPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFL----SDDPESYKPCDPEIIVSRVQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDALHKQAES-LKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKD---------DTPVNLEQAENQLKRHEAFLTTMEANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRALDQHEKLKNQVKLHEFLQDLEELAEWVQEKYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKERLFEAEKSAQELSKEKPEFKDVIEPKLKELAKQFDDLEVHTKEKGAMLFDANREVLVQQTCDDIDSYITDLEKQIVSGD----TANDLTSVNILMQKQQVIQTQMAVKARQVEEIDKQTEYLQKTVPEE--KIEPIVVKKTAVLERFEKIKAPLLERQKALEKKKEAFQFCRDVEDEKLWIDEKLPV----ANSPDYGNSLFNVHVLKKKNQSLATEIDNHEPRINAICNNGRKLIDEGHEDAKKFEALISDLTQKWQELKDAIENRRKHLLESEKVQQYFFDAQEAESWMSEQELYMM-VEDRGKDEISAQNLMKKHENLEQSVEDYANTIRQLGEVARQFSGDDISSGDAVAVKQSQLDKLYAGLKDLAGERRARLNEALQLFMLSREV----DDLEQWITDREVVAGSQELGQDFDHVTLLSERFNEFARDTEAVGGERVAKVNGIADNLIQAGHSDSATIAEWKDNLNESWQDLLELIETRTQMLAASRELHKFFHDCKDVLGRILEKQHG--VSDELGRDAGSVSTLQRKHYNFLQDLITLYSQVQQIQEESAKLQDAYAGDKAKEITNREQEVLHAWDNLQAMCDARKQKLADTGDLFRFFNMVRILMIWMEDLVRQMNTSEKPRDVSGVELLMNNHQSLKAEIDTREDNFGACISLGKELLTRNHYASADIKDRLMTLSNSRNALLRRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLLSSELGHTIDEVENLIKKHEAFEKSAAAQEERFSALERLTTFELKEMK 2089 HSP 2 Score: 131.724 bits (330), Expect = 6.911e-30 Identity = 140/618 (22.65%), Postives = 280/618 (45.31%), Query Frame = 1
Query: 4612 QFLQDCDDEIDWMNEKIDLIRNR--SKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVIN---SKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLP---DEYKGIVKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ---NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELID-AFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRS-PE---IKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNT 6417
QF D DE +W+ EK ++ + T+ +L +HK++++EI + ++ ++ + +I E H + D + ++ ++L + + + L N + + D +V +W+ LD + +V + +D+ ++ +++K +++ E+KNY I+ K SL E + K +E N K + K + Y+L +E WI E+TK+ + GKD++ +++ RF F E N +S+V N+ +L+ +HP + I ++ +N+ W+ L E + ++ LKSA + +Y + + + I++KK + + L D V LQR+L ++DL + + +++ +N++ + + EA +I++R I+ + L ++L++R E D H FL + W+ + + P + E LL H+S++ E+D+ E++ + G L P+ ++ + + D + L Q W N LS ++ + RDA E + QE +L+ ++ + L++ LK+ F LTTME K+NT
Sbjct: 639 QFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLS------KHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWM----LDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDALHKQAESLKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMN-ANASRVAVVNQLARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPE--EAKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRHEAF----------------LTTMEANDDKINT 1227 HSP 3 Score: 88.9669 bits (219), Expect = 6.737e-17 Identity = 44/154 (28.57%), Postives = 80/154 (51.95%), Query Frame = 1
Query: 6844 KGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFSSIRLK 7305
+G + RKH+W++ +KASNR+W +Y+ R++F+KD++ +K P+ ++ E L A DY K+ V RV+ NGA +L Q +M++WV ++ + S +T + S +LP +Q + +R F +++ K
Sbjct: 2168 EGYVTRKHEWDSTTKKASNRSWDKVYMAAKAGRISFYKDQKGYKSNPELTFRGEPSYDLQNAAIEIASDYTKKKHVLRVKLANGALFLLQAHDDTEMSQWVTSLKAQS-------------DSTAVAASRSQTLPATSQKDEPKRRSFFTLKKK 2308
BLAST of Spectrin beta chain vs. Ensembl Fly
Match: beta-Spec (gene:FBgn0250788 transcript:FBtr0334405) HSP 1 Score: 1298.49 bits (3359), Expect = 0.000e+0 Identity = 780/2103 (37.09%), Postives = 1245/2103 (59.20%), Query Frame = 1
Query: 148 NALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLK--SEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQL---ETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKI-------EEFKKSCVSLPDEYKGIVKDVEDNFNSLKIICAEKKTEIS----LFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKK 6408
N DE E N +S++FERSRIKALA+ERE+VQKKTFTKW+NS L V +I DLYVD+RDGK L+ LLE+LS E +PKPT+G+MRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN L LGLIWTIILRFQ+QDI +E + KSAKDALLLWCQMKTAGY +VN+RNFT SWR GL F A+IHKHRPDL+ F ++ + I+NL+ AFD+AE+ LG+ LLD EDV V PDE+S+ITYV +YYHYF+ LK +V KR+ K++ +E+++M+ Y++ S LL+WI TI+ L R+F NS+ G+Q Q+ F+ YRT EKP KFVEK +LEVLLFT++S + K Y P E +S IN AW+ L AE+ RE ALR+EL+RQEKL LA +F++KA++RE+W+++N L+ + + G +L V AA KKHEAIETDI+AYEE + + + D LE E Y+D+ I+ K+ V+ LW LL+ L RR L+ LQ+ E + + I D+YGKHLM VE+LL+ H L+E+DI + +R++ ++ + +++ D + + +I + + EL+ +R+ L+ S +WQF D + EE WIKE I++ ++G+DL++V+ +L KHK E E++S L+N G L+ G + I + +I N W+ L+D T+ R+ +L ++Y+Q +D DD + W+ + R+ + +G + + L++K++ + ++NY + I+ + QA+S L + + V K+L+ I+ +Y++L ++A +++LLDAL++Y+L++++D V WI EK K L P DIE++E++KHRFE F+ E+ A +V VN L+ L+ +PN I+ Q++LN W+ + + ++K D+L S + F+++C++TI WI +K +++ D L DL VM QRR++ M RD+ AI+AK+ L + + I + AK I ++ + WE L Q++++RDS L D+HRF++ LD F WL + QT++AS++ P S EAEKL+N++ S R+E+ + + M+ G+ S D Q++ L+ R+ ++ W+ L+ + E ++ L + L +F DARQ E +L+ QE +L KD + NL + +E F+ M +++ + +L+ TL+ +++ D++ + +N+ R N A ++ KLK QV LHE LQD+++L + + EK + S + K+ S + +A E EI A + + E K ++ S + P FK I L L + +L +EK L NRE L +++ + ++ ++E QIV+ D + + +TS+ ++K ++ K + +E + +E L++ P++ K E + +T V + + PL + +K A QF +D +DE W++EK+ + + + +L L+ +++S+ EI N +++++ +++IDE H ++ L + + L + +E + L VQ++ D E SW+SE+EL +M + KD+ + +++K +NLE +++Y I +F +S D ++ + LK + E++ ++ LF++ + ++E WI +R +A S + G+D D TLL +RF F+ +T +G +V + N D LIQ H + +I+ WKD +NE W DLLELI+TR Q+L ++ +LH+++ D + +L I EK+ V ++LG+D SVS LQRK NF +DL+ L S + S L Y DK + + QE++ A+ +L+ + + RK + D F +MVR L+ W+E++ QM KPRDVSG+ELL+ NH+SLK E+D++E+NF C++LG+ LL H S +IK + +++ R+ L ++W ++L L++EVYQ+ARDAA AEAW+I+QE YL + LG T+DE L+KK F+K+ QEE+F L+RLTT E++ K
Sbjct: 18 NEYIDEYEYDGGNSSSRLFERSRIKALAEERESVQKKTFTKWVNSHLCRVNCRIADLYVDMRDGKHLIKLLEVLSGERLPKPTKGKMRIHCLENVDKALQFLREQRVHLENIGSHDIVDGNASLNLGLIWTIILRFQIQDITIEEVDNKETKSAKDALLLWCQMKTAGYHNVNVRNFTTSWRDGLAFNAIIHKHRPDLVQFEKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDVFVEHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMENDKMVHDYENFTSDLLKWIETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQSKMRANNQKPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFL----SDDPESYKPCDPEIIVSRVQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDALHKQAES-LKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKD---------DTPVNLEQAENQLKRHEAFLTTMEANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRALDQHEKLKNQVKLHEFLQDLEELAEWVQEKYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKERLFEAEKSAQELSKEKPEFKDVIEPKLKELAKQFDDLEVHTKEKGAMLFDANREVLVQQTCDDIDSYITDLEKQIVSGD----TANDLTSVNILMQKQQVIQTQMAVKARQVEEIDKQTEYLQKTVPEE--KIEPIVVKKTAVLERFEKIKAPLLERQKALEKKKEAFQFCRDVEDEKLWIDEKLPV----ANSPDYGNSLFNVHVLKKKNQSLATEIDNHEPRINAICNNGRKLIDEGHEDAKKFEALISDLTQKWQELKDAIENRRKHLLESEKVQQYFFDAQEAESWMSEQELYMM-VEDRGKDEISAQNLMKKHENLEQSVEDYANTIRQLGEVARQFSGDDISSGDAVAVKQSQLDKLYAGLKDLAGERRARLNEALQLFMLSREV----DDLEQWITDREVVAGSQELGQDFDHVTLLSERFNEFARDTEAVGGERVAKVNGIADNLIQAGHSDSATIAEWKDNLNESWQDLLELIETRTQMLAASRELHKFFHDCKDVLGRILEKQHG--VSDELGRDAGSVSTLQRKHYNFLQDLITLYSQVQQIQEESAKLQDAYAGDKAKEITNREQEVLHAWDNLQAMCDARKQKLADTGDLFRFFNMVRILMIWMEDLVRQMNTSEKPRDVSGVELLMNNHQSLKAEIDTREDNFGACISLGKELLTRNHYASADIKDRLMTLSNSRNALLRRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLLSSELGHTIDEVENLIKKHEAFEKSAAAQEERFSALERLTTFELKEMK 2089 HSP 2 Score: 131.339 bits (329), Expect = 8.032e-30 Identity = 140/618 (22.65%), Postives = 280/618 (45.31%), Query Frame = 1
Query: 4612 QFLQDCDDEIDWMNEKIDLIRNR--SKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVIN---SKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLP---DEYKGIVKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ---NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELID-AFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRS-PE---IKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNT 6417
QF D DE +W+ EK ++ + T+ +L +HK++++EI + ++ ++ + +I E H + D + ++ ++L + + + L N + + D +V +W+ LD + +V + +D+ ++ +++K +++ E+KNY I+ K SL E + K +E N K + K + Y+L +E WI E+TK+ + GKD++ +++ RF F E N +S+V N+ +L+ +HP + I ++ +N+ W+ L E + ++ LKSA + +Y + + + I++KK + + L D V LQR+L ++DL + + +++ +N++ + + EA +I++R I+ + L ++L++R E D H FL + W+ + + P + E LL H+S++ E+D+ E++ + G L P+ ++ + + D + L Q W N LS ++ + RDA E + QE +L+ ++ + L++ LK+ F LTTME K+NT
Sbjct: 639 QFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLS------KHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWM----LDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDALHKQAESLKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMN-ANASRVAVVNQLARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPE--EAKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRHEAF----------------LTTMEANDDKINT 1227
BLAST of Spectrin beta chain vs. Ensembl Fly
Match: kst (gene:FBgn0004167 transcript:FBtr0073071) HSP 1 Score: 518.85 bits (1335), Expect = 5.385e-148 Identity = 364/1159 (31.41%), Postives = 580/1159 (50.04%), Query Frame = 1
Query: 202 FERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFD---EDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSC--NRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLL--GYSIVDHQTVAKKLDRIE--------------------------KKYQDLLDIAH-------KMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNG---------------------------NPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIG 3477
FE RIK L +ER ++QKKTFTKW+NS LI M++EDL+ DL DG LL LLE++S+E + KP GRMR+H +ENV+K L FL KV LE++GA DIVDGNPRL LGLIWTIILRFQ+Q+I+ D E+ S +SAKDALLLWCQ KT GYP VNI +FTNSWR+GLGF ALIH HRPDL ++S+ ++N N++NL+ AFD A N LGIPSLLD ED++ PDE+S++TYVASYYH F +K KR+ ++ Q+++ ++ Y+ L + LL WIR L R NS+ GIQ+++ F YRT EKP K+ E+ ++E L FTI + YNP + ++ I AW L AE+ RE ALR EL+RQEKL L KF KK+ LRE ++ E++Q S L V A LKKHEAI DI A E LT +++ L+ E Y+ + + +V+ W++LL+ L +R +L + L+ E + + + ++ G HL+ VEELL++H L E + + + L++ +A Y +D A++ ++ + + ELL R+ L+ + F+ D EE W+ + I DL +V L +KHK E E+ S++ GK L+ I ++ + + W+AL E R+ +L + + YQ+ +D ++AE W++E L + + G+ + L+++++ + Y +I + QA L+ G ++ +L +E KK + + H + Q +D V LL + W K + F+P++ + E+E + + +AEKV + + + ++V N N + Q +N +++++ ++ + L H F+ +C +W++EK ++I+S ++ E V +R+ D+ A +++ + D R I + +HQ W+ L R+ +L + + F + D+ W+ + ++ + I + L ++ + E+A +E ++ +G
Sbjct: 10 FENERIKTLQEERLHIQKKTFTKWMNSFLIKAKMEVEDLFTDLADGIKLLKLLEIISSEKLGKPNSGRMRVHKIENVNKSLAFLHT-KVRLESIGAEDIVDGNPRLILGLIWTIILRFQIQEIEIDVDEENESSEKRSAKDALLLWCQRKTHGYPGVNITDFTNSWRSGLGFNALIHSHRPDLFEYSTIVNSKNSNLDNLNHAFDTAANELGIPSLLDAEDIDSARPDEKSILTYVASYYHTFARMKNEQKSGKRIANIVGQLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTLLKALNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSVLREGYLK---EMIQVLSDPRYLRQVDATLKKHEAISADILARVERFNDLTAMAEELDRENYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKD---------AALLAQRLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVKSLFPFEGQGMKMDKGEVM-LLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRP------VACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKS-----DEGEGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLG 1143 HSP 2 Score: 331.643 bits (849), Expect = 1.850e-90 Identity = 459/2016 (22.77%), Postives = 884/2016 (43.85%), Query Frame = 1
Query: 1426 QSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYV-QFCDQDFRSNINSGNKAM--IKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFE--LELSSKRISL----ENKLMEGKTL--VDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEIL--------IRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGN--PNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKID-HLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLK--SEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLK---QGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSEL---LKQQNPD--KASKYEQLETQVKVTM-----DGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNM-------LSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPD----EYKGIVK---DVEDNFNSLKIICAEKKTEIS----LFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELAD-FHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEI---------RSKKLNTDRQFINEALINIEQ------TAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTG---YFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAIN-SASRPMRQVNPSNTNPSTTQSHPNLSSSLP 7248
Q LG +L + LA L+KHE E D+ A E L L + S L+ + ++ +I ++KV+ W L + R + L + T + + ++ + + + A + + + L H+ I +I + + RY+ + D S + +G+ A ++EK + + + +L + +K+K +L+ ++ F+ DA + +++ D G + V +RKH FE ++ +++SL KL+E + +I + Q +A + + + D R+ KL + L Y ++V DC +A+ WI+E ++ K D S+ E+ ++K+Q V + I++I++ LL + + ++ + + +Q LL + L +A + D + +WI +K+ + D+E L + + +S++ ++V H+N L++ L+ + Q + + + N +W ++ +++ R L F D T + I EK + S D G DL +V RR ++RD+ A++ KID H A I ++ R A+ IE +L+ +H+ W LQ L R S L H+F+ + + W+ M +M + P + ++ E + + ++ E+ ++ + G+ K +Q D + +E ++Q LN+ E+ + L + + +F Q+E L +E +L D L +++ + L +E E + D + + +K +L+ + LI E Y R + K L E RK +L + L E L+ + ++D L++K+QV + + + S + + A + E+ + P ++ + G++ K EI + L W +L A + K L F S W+ +E Q+ ++D + +++N LKK + +L ++ H EL LKQ++ +A + + E + T+ + L PL + + +QFL+D +DE+ W+ EK L+ S+ + T +LL Q LQ +H S++ E+ ++ + +L+Q Q+MI +NH QL+ E L +++ + +++ L + + Q F ++ +E +W+ EK ++ +D+ ++ +K + L+ E+ + P IE+ K L + + I + V + L + E+++ + LF +T EL++ W+ ++ + S+D G+D++ L F F S N ++V +R D LIQ +P+ SI +D ++W +L +L+ R L A +H + + ++ I EK +S+ + D G+D +S+ L RK + FE +L+ + +++ + + L +Y KE +K R E ++A+ L++ RK N L A+ ++ R+L+ WI E+ ++ V+G ELLLA+ + E+ +++E F+ G+ L++ KH + E++ K K + + ++L + L ++ + +DA E W+ S+E L + LG ++ + LL++ F+K QEEKF+ +KR+T +E + KL + E L ++Q E E +N + E PI P Q + S + D QK +S + SA + V + +S + QP + + + +PP E+ +G L RKH ++ +KA R+W + +L + FFKDE F ++ P+ + A DY K+ VFR++ +G+E+LF+ S+ + WV I+ AS P P+ S +S SSS P
Sbjct: 1950 QELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKF--------RYLNELSD----SMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARR--------QKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQK----KLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTD-TGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQ---TLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNND--DLGDSYTAVERLLKKHDEF--EKLLHADHVDTLQKFANSILEGEPKDADLIREKLAYILRRKQKLLELSE----------ERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYG----KDLAAVSNLLKKHE----------RLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEK-QLVAG-SQDLGT--SLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQMIRDNHF-------ASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMREKR-PVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHE----WVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNLN-ANEARVEACLERGDRLIQENNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASL-ISEDYGQDLESIQALGRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVK-RDETVEAWTDLKEKTAARK-NKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTRDETFAKFAANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRREIYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQAIKRITMLEQLFRHQLEQEKISKLQEKERLEKERLEQLKQRELQRLADERRRAEKQHEHRQNAASQEKTPIFSSPMVTPAQTSGPQSPALSQVQLRPPFGDDNEHLALQKSSSSGMFGDRLRRGSADANVKRA-ESMKVQPKQAKRTPSFTTRRRAQSFRKNQKGEGFDLPPVEI--QGSLERKHGLQSGGKKAPVRSWKQFHTVLCGQLVCFFKDENDFLQQKTAT----APVNILGAKCERADDYTKKKYVFRLKLPDGSEFLFEAPSLDILNDWVRKISFHASLP-----PNMQLLSYDESMKQQSSSSP 3877 HSP 3 Score: 225.328 bits (573), Expect = 3.094e-58 Identity = 274/1295 (21.16%), Postives = 587/1295 (45.33%), Query Frame = 1
Query: 2557 TVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHN----WLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFV----RLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGK---QTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXD---HSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQN-IEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLK 6375
+V K+ RI + Y +L ++A K L D++ ++ + D W+ EK++ I SD+ E ++ K +FE F ++L+ +++V ++ + G+ I+ Q ++ W ++ + + L F C + W+ EK+ +++ + DL +V QRR +++R++ +E K++ + G+ + ++ + KD ++ QE + + Q ++ R S L N+ + Q ++ W+ ++ ++ + A L+ K+N D++ A + + E +++GK + + + V RL+ ++I++ W EK+K L + + MF +A +I+ + E +L +N ++L + I+ + F +++ +K+L LI ++ + ++ + + K A RK L+ H+ + DDL L +K ++ + + + + L + +A E E+ A + + K G+ Q P + + D LN W +L E+K + L ++ S + K + ++ + + D + RS + N+ + L+S + K L + D H QN + +K +L+ + K D P + + + + + +F+ + D E W+NE + +K E L Q Q L +HK ++ EI+ ++ + Q +I + H +R V QL++ ++L + L L Q++L D E+ SW+ E+ +++ +D +++ K + +E+E+ Y + E SC ++ PD K +E SL + ++++ + + +Y Y L + +E WI E+ + A S+D G+D + LL+++F ++G+ +V++ +LI + P+A+ + ++++ W +LL+L++ R Q L +A ++HR++ D L IQ+K +++ +LG+D S L RK + FE DL+ L++ + + S L Y + A + +++ +++ A+ L++ R +D FL+ VR+++ W + ++ D +G L H ++ E++++E+ F L ++++T H + +++ KC + D+R L W L ++++ + RDA + SQ++ L++ + G T+++ ++K F++ QEEK L+
Sbjct: 948 SVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERM----IKSDEGEGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTA-VITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSV-KNAYPAEKD---NVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQLGKQLSDGKPNMAETVAVIERLKAEQDAIHRGW-------AEKQKWLLQCVDLQMFNREADKIDATTKSHEAFL---------EYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGNRVPEVESRVAD----LNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRS-CKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTK--ELQQRFKDLRD----PTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPA----AKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERN-NVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRL-MESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRV-EVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAALS--QELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASA-IAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQ 2196 HSP 4 Score: 149.828 bits (377), Expect = 2.433e-35 Identity = 157/726 (21.63%), Postives = 325/726 (44.77%), Query Frame = 1
Query: 1297 GRETALRKELMRQEKLRNLAQKFNKKAALRES---WITDNMELLQKQSLGN--NLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDL---WKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLG-DKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAME 3447
G+ A++ +++L ++ F+K AA + W+ D + ++ + NLP L+KH+A E ++ A E L +TK L + N + + +++V DL WK LL ++ L+ + + + + + R + G L ++L+ +++ES+I +Q++ +L+S + + + NI +G K + + F +L D +R+ L+ S +F+ + E QWI E + + +LG +L L +KHK E E+ + + L+ G++L+ +E + + ++ W+ L R KL L QY+ D + E W+ E + G D+ S ++L + +E+ + Y + ++ + +++ + D + +A K IEK + L +A + Q +L+++L + +SD V WI E+++ + D E L++L+++F+ + + A++V L++ L+ + +P + Q+ L SW + +++ + +L + F D + + I++K + ELG DL S + R+ + D+ A+EA++ LV + +A I Q D V W L++ R LA +D+ F+ + D +W ++ + ++ + A L ++++ E+ A E
Sbjct: 1377 GKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLSNLPR---KLQKHQAFERELRANEGQLRNVTKDGQALVQ-AGNRVPEV---ESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQ-NIEAGTKELQQR--------FKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELEL-DTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAALSQ--ELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEARE 2083 HSP 5 Score: 112.079 bits (279), Expect = 7.477e-24 Identity = 114/498 (22.89%), Postives = 223/498 (44.78%), Query Frame = 1
Query: 1354 AQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEIL---KHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLS 2838
+Q F +A ++W+ + +L G + +V KK E ++ ++ A++ ++ + K++ L E + D +I +V ++ LL+ ER L +++ + E E+ + A ++YG+ + VE+L+ + E S++ + R+E + +R +Q N+ ++ IK KR+ T + + EL D + R++ L K H V+ + D ++ Q I E + + D G DL S+ L RKH+VFE EL + +++ L E L +I P +E I K ++ W L + T +RK KL + Y + D WI+E L + ++ E+L+ + + + + + Q L+ V K+ ++ +++ L +K +E L L D++ + WI+ ++ L + D I ++E L R E FE + + EK + ++
Sbjct: 3097 SQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNLNANEARVEACLERGDRLIQE---------NNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVH-VYDRVADETI--QLINEKDASLISEDYGQDLESIQALGRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKRDETVEAWTDLKEKTAARKNKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTRDETFAKFAANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRREIYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQAIKRIT 3582 HSP 6 Score: 98.2117 bits (243), Expect = 9.956e-20 Identity = 152/808 (18.81%), Postives = 335/808 (41.46%), Query Frame = 1
Query: 1033 WIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTG-EKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKT-----LVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEI--LIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQT----VAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNS 3420
W++ R++ S+ G+ F + T SK VE++D V F + + + ++ I+ W LN A+ RE +L + + FN+ + W+++ M L + +L TV A ++H+ +E ++ E+ + +T + ++++ + ++ + +V D+W+++ Q + R +++ + N + A I + + D + + LL+ H + DIR+ + +E +Q Q N + E+ + H +K+K +L+ L F +A + K + +LG L V+ +L++H FE K + ++K+++G + L+ ++I + N + +A+ D RK L D++++ ++ DD + W+ + R+ GD+ ++ ++ L RK Q++ R N Q+RN + G ++V V ++ + K+++DLL ++ KL A + + + + E L + +D+ + L ++ ++ ESE+T +KV + + +++ G+ N Q I L + + D +R +L +Y F + +WI E + +S +ELG++L ++ ++ +I + I+ + G ++ + +E + Q W+ L++ +R L +++ + +WLG+ + S + A KL+ K+ +
Sbjct: 993 WMKEKERMIK----SDEGEGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQ-------RQIHQIWQRLNNAKAQREKSLEGA--------SSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHD-------TEFVEVIQLGKQLSDGKPNMAETVAVIERLKAEQDAIHR--GWAEKQKWLLQCVDL-QMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFE-----KSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRI-----AGDE-NYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKD--GQALVQAGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKS-NELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKT 1757 HSP 7 Score: 60.8474 bits (146), Expect = 2.363e-8 Identity = 175/929 (18.84%), Postives = 384/929 (41.33%), Query Frame = 1
Query: 2263 IQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLF---DLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDS-DSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVN-NQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEI------LRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNN-KSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHS-----ELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNR--SKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKE 4992
I ++ L + + R L + + + + +CDD E W+ E +R+ + + + + E I + VE ++ R Q S L I + + + R L+ A +EK L+ + L N + D + W++EK L + + D+ ++ L+ R + E EL +KV V L N V N P + VN Q + + W ++ R+ + S+ F + + WI + +K + DE D+E+ ++ N + DI A + + ++ G ++ + + + ++ + D +H+ W ++ L D+ F ++ D + + N+ S E E ++ ++ + A ++ L+ + + ++ +++ +R + K + D + E+++ L+ F +A + K ++D + + N +L +L + +++ F ++ ++E L V K G+ L+ N + ++++ +L++RWK ++++ KL++ E + ++D + E L + N+ +S + + + LE EI + + EL G A HF + N+ + EL + ++ L++ R KL E + + E Q + + P + + +Q + L + +LE + K + + + + L+ QQ+P++ + E L Q++ L + + + A+Q+L D + W+ E+ +++R+ + ++ LL +HK+++ E+ S V + M+ NH ++ ++K ++L++ + Q L L E+ L+ EV WI E+E
Sbjct: 956 INQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSDEGEGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQR--------LNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLG-NSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWI-DSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQLGKQLSDGKPNMAETVAVIERLKAEQDAIHRGWA-------EKQKWLLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYI--GDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDL--------KVWLQDKTRIAGDENY--RDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGNRVPE-VESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDM-AHGGHFNAQ------NIEAGTKELQQRFKD-LRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPER-EQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLL------TKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQE 1839 HSP 8 Score: 60.8474 bits (146), Expect = 2.383e-8 Identity = 120/596 (20.13%), Postives = 248/596 (41.61%), Query Frame = 1
Query: 4489 QNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTL-LQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEE-------FKKSCVSLPDEYKGIVKDVEDNFNSLKIICAEKKTEISLFV---IYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQ-------GKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWD-LHRWYCDSQ-FLLECIQEKKSSMEV---------------VNDLGKDPKSVSLLQRKLKNFEKDLLKLD------SDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDK-RDIL 6150
+N D K +Q ++ T D L + + ++ I F ++CDD WM EK +I +S + E + +F++ + + VD+ ++ +D+ ++ Q+ + + LN + + L +V+ F E W+SEK L L VI + D + ++ + R+ QNLE E+ K+ K + + D ++V+D + ++ ++ + I V ++ ++ ++ + AWI +D+S +D++ L + N +G + + F E+IQ GK A +++V I+ LK+ D +HR + + Q +LL+C+ + + E N+LG V + ++ +FEK L+ D SD + + ++ Y D+ ++ KR+ + D +++L+ K DFH F + +L W+++ T ++ RD+S + L H++ + E+ + E G+ L++ + R PE++S+ ++ + +D+L
Sbjct: 944 ENADSVEKRQQ---RINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMI--KSDEGEGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDK-------IIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVI-TPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKV---LLAWIDSVKDQLNADESARDVETANNLLKKH-------NDLGDD-IRAHDTEFVEVIQLGKQLSDGKPNMAETVAV-------------------IERLKAEQDAIHRGWAEKQKWLLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASK-------DFHKFAAEADDLKVWLQDKT-RIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGN-RVPEVESRVADLNKRWKDLL 1487 HSP 9 Score: 57.3806 bits (137), Expect = 2.236e-7 Identity = 52/188 (27.66%), Postives = 89/188 (47.34%), Query Frame = 1
Query: 5251 ELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSE--TNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVN--DLGKD-PKSVSLLQR------KLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKE 5781
E Y N E+W+V++ +I ++ + KDL L+ + E + K S +++ A KR LI +HP + I D + E W L L++ R + L+ A + +++Y D+ + EK + +VN D G D P + +LLQR +L + D+L L+ + I L L + E
Sbjct: 612 EDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQMSTAGKR---LIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFYTDANEAESWLNEK---IALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKLIKAGICTLELSAAEPE 793
BLAST of Spectrin beta chain vs. Ensembl Fly
Match: kst (gene:FBgn0004167 transcript:FBtr0300017) HSP 1 Score: 518.85 bits (1335), Expect = 6.317e-148 Identity = 367/1170 (31.37%), Postives = 585/1170 (50.00%), Query Frame = 1
Query: 181 ANVTSK----VFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFD---EDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSC--NRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLL--GYSIVDHQTVAKKLDRIE--------------------------KKYQDLLDIAH-------KMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNG---------------------------NPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIG 3477
AN+T + FE RIK L +ER ++QKKTFTKW+NS LI M++EDL+ DL DG LL LLE++S+E + KP GRMR+H +ENV+K L FL KV LE++GA DIVDGNPRL LGLIWTIILRFQ+Q+I+ D E+ S +SAKDALLLWCQ KT GYP VNI +FTNSWR+GLGF ALIH HRPDL ++S+ ++N N++NL+ AFD A N LGIPSLLD ED++ PDE+S++TYVASYYH F +K KR+ ++ Q+++ ++ Y+ L + LL WIR L R NS+ GIQ+++ F YRT EKP K+ E+ ++E L FTI + YNP + ++ I AW L AE+ RE ALR EL+RQEKL L KF KK+ LRE ++ E++Q S L V A LKKHEAI DI A E LT +++ L+ E Y+ + + +V+ W++LL+ L +R +L + L+ E + + + ++ G HL+ VEELL++H L E + + + L++ +A Y +D A++ ++ + + ELL R+ L+ + F+ D EE W+ + I DL +V L +KHK E E+ S++ GK L+ I ++ + + W+AL E R+ +L + + YQ+ +D ++AE W++E L + + G+ + L+++++ + Y +I + QA L+ G ++ +L +E KK + + H + Q +D V LL + W K + F+P++ + E+E + + +AEKV + + + ++V N N + Q +N +++++ ++ + L H F+ +C +W++EK ++I+S ++ E V +R+ D+ A +++ + D R I + +HQ W+ L R+ +L + + F + D+ W+ + ++ + I + L ++ + E+A +E ++ +G
Sbjct: 50 ANMTQRDGIIKFENERIKTLQEERLHIQKKTFTKWMNSFLIKAKMEVEDLFTDLADGIKLLKLLEIISSEKLGKPNSGRMRVHKIENVNKSLAFLHT-KVRLESIGAEDIVDGNPRLILGLIWTIILRFQIQEIEIDVDEENESSEKRSAKDALLLWCQRKTHGYPGVNITDFTNSWRSGLGFNALIHSHRPDLFEYSTIVNSKNSNLDNLNHAFDTAANELGIPSLLDAEDIDSARPDEKSILTYVASYYHTFARMKNEQKSGKRIANIVGQLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTLLKALNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSVLREGYLK---EMIQVLSDPRYLRQVDATLKKHEAISADILARVERFNDLTAMAEELDRENYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKD---------AALLAQRLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVKSLFPFEGQGMKMDKGEVM-LLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRP------VACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKS-----DEGEGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLG 1194 HSP 2 Score: 331.643 bits (849), Expect = 2.092e-90 Identity = 459/2016 (22.77%), Postives = 884/2016 (43.85%), Query Frame = 1
Query: 1426 QSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYV-QFCDQDFRSNINSGNKAM--IKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFE--LELSSKRISL----ENKLMEGKTL--VDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEIL--------IRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGN--PNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKID-HLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLK--SEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLK---QGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSEL---LKQQNPD--KASKYEQLETQVKVTM-----DGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNM-------LSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPD----EYKGIVK---DVEDNFNSLKIICAEKKTEIS----LFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELAD-FHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEI---------RSKKLNTDRQFINEALINIEQ------TAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTG---YFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAIN-SASRPMRQVNPSNTNPSTTQSHPNLSSSLP 7248
Q LG +L + LA L+KHE E D+ A E L L + S L+ + ++ +I ++KV+ W L + R + L + T + + ++ + + + A + + + L H+ I +I + + RY+ + D S + +G+ A ++EK + + + +L + +K+K +L+ ++ F+ DA + +++ D G + V +RKH FE ++ +++SL KL+E + +I + Q +A + + + D R+ KL + L Y ++V DC +A+ WI+E ++ K D S+ E+ ++K+Q V + I++I++ LL + + ++ + + +Q LL + L +A + D + +WI +K+ + D+E L + + +S++ ++V H+N L++ L+ + Q + + + N +W ++ +++ R L F D T + I EK + S D G DL +V RR ++RD+ A++ KID H A I ++ R A+ IE +L+ +H+ W LQ L R S L H+F+ + + W+ M +M + P + ++ E + + ++ E+ ++ + G+ K +Q D + +E ++Q LN+ E+ + L + + +F Q+E L +E +L D L +++ + L +E E + D + + +K +L+ + LI E Y R + K L E RK +L + L E L+ + ++D L++K+QV + + + S + + A + E+ + P ++ + G++ K EI + L W +L A + K L F S W+ +E Q+ ++D + +++N LKK + +L ++ H EL LKQ++ +A + + E + T+ + L PL + + +QFL+D +DE+ W+ EK L+ S+ + T +LL Q LQ +H S++ E+ ++ + +L+Q Q+MI +NH QL+ E L +++ + +++ L + + Q F ++ +E +W+ EK ++ +D+ ++ +K + L+ E+ + P IE+ K L + + I + V + L + E+++ + LF +T EL++ W+ ++ + S+D G+D++ L F F S N ++V +R D LIQ +P+ SI +D ++W +L +L+ R L A +H + + ++ I EK +S+ + D G+D +S+ L RK + FE +L+ + +++ + + L +Y KE +K R E ++A+ L++ RK N L A+ ++ R+L+ WI E+ ++ V+G ELLLA+ + E+ +++E F+ G+ L++ KH + E++ K K + + ++L + L ++ + +DA E W+ S+E L + LG ++ + LL++ F+K QEEKF+ +KR+T +E + KL + E L ++Q E E +N + E PI P Q + S + D QK +S + SA + V + +S + QP + + + +PP E+ +G L RKH ++ +KA R+W + +L + FFKDE F ++ P+ + A DY K+ VFR++ +G+E+LF+ S+ + WV I+ AS P P+ S +S SSS P
Sbjct: 2001 QELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKF--------RYLNELSD----SMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARR--------QKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQK----KLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTD-TGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQ---TLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNND--DLGDSYTAVERLLKKHDEF--EKLLHADHVDTLQKFANSILEGEPKDADLIREKLAYILRRKQKLLELSE----------ERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYG----KDLAAVSNLLKKHE----------RLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEK-QLVAG-SQDLGT--SLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQMIRDNHF-------ASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMREKR-PVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHE----WVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNLN-ANEARVEACLERGDRLIQENNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASL-ISEDYGQDLESIQALGRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVK-RDETVEAWTDLKEKTAARK-NKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTRDETFAKFAANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRREIYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQAIKRITMLEQLFRHQLEQEKISKLQEKERLEKERLEQLKQRELQRLADERRRAEKQHEHRQNAASQEKTPIFSSPMVTPAQTSGPQSPALSQVQLRPPFGDDNEHLALQKSSSSGMFGDRLRRGSADANVKRA-ESMKVQPKQAKRTPSFTTRRRAQSFRKNQKGEGFDLPPVEI--QGSLERKHGLQSGGKKAPVRSWKQFHTVLCGQLVCFFKDENDFLQQKTAT----APVNILGAKCERADDYTKKKYVFRLKLPDGSEFLFEAPSLDILNDWVRKISFHASLP-----PNMQLLSYDESMKQQSSSSP 3928 HSP 3 Score: 226.868 bits (577), Expect = 1.370e-58 Identity = 274/1295 (21.16%), Postives = 587/1295 (45.33%), Query Frame = 1
Query: 2557 TVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHN----WLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFV----RLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGK---QTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXD---HSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQN-IEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLK 6375
+V K+ RI + Y +L ++A K L D++ ++ + D W+ EK++ I SD+ E ++ K +FE F ++L+ +++V ++ + G+ I+ Q ++ W ++ + + L F C + W+ EK+ +++ + DL +V QRR +++R++ +E K++ + G+ + ++ + KD ++ QE + + Q ++ R S L N+ + Q ++ W+ ++ ++ + A L+ K+N D++ A + + E +++GK + + + V RL+ ++I++ W EK+K L + + MF +A +I+ + E +L +N ++L + I+ + F +++ +K+L LI ++ + ++ + + K A RK L+ H+ + DDL L +K ++ + + + + L + +A E E+ A + + K G+ Q P + + D LN W +L E+K + L ++ S + K + ++ + + D + RS + N+ + L+S + K L + D H QN + +K +L+ + K D P + + + + + +F+ + D E W+NE + +K E L Q Q L +HK ++ EI+ ++ + Q +I + H +R V QL++ ++L + L L Q++L D E+ SW+ E+ +++ +D +++ K + +E+E+ Y + E SC ++ PD K +E SL + ++++ + + +Y Y L + +E WI E+ + A S+D G+D + LL+++F ++G+ +V++ +LI + P+A+ + ++++ W +LL+L++ R Q L +A ++HR++ D L IQ+K +++ +LG+D S L RK + FE DL+ L++ + + S L Y + A + +++ +++ A+ L++ R +D FL+ VR+++ W + ++ D +G L H ++ E++++E+ F L ++++T H + +++ KC + D+R L W L ++++ + RDA + SQ++ L++ + G T+++ ++K F++ QEEK L+
Sbjct: 999 SVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERM----IKSDEGEGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTA-VITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSV-KNAYPAEKD---NVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQLGKQLSDGKPNMAETVAVIERLKAEQDAIHRGW-------AEKQKWLLQCVDLQMFNREADKIDATTKSHEAFL---------EYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGNRVPEVESRVAD----LNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRS-CKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTK--ELQQRFKDLRD----PTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPA----AKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERN-NVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRL-MESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRV-EVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAALS--QELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASA-IAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQ 2247 HSP 4 Score: 150.214 bits (378), Expect = 2.009e-35 Identity = 157/726 (21.63%), Postives = 325/726 (44.77%), Query Frame = 1
Query: 1297 GRETALRKELMRQEKLRNLAQKFNKKAALRES---WITDNMELLQKQSLGN--NLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDL---WKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLG-DKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAME 3447
G+ A++ +++L ++ F+K AA + W+ D + ++ + NLP L+KH+A E ++ A E L +TK L + N + + +++V DL WK LL ++ L+ + + + + + R + G L ++L+ +++ES+I +Q++ +L+S + + + NI +G K + + F +L D +R+ L+ S +F+ + E QWI E + + +LG +L L +KHK E E+ + + L+ G++L+ +E + + ++ W+ L R KL L QY+ D + E W+ E + G D+ S ++L + +E+ + Y + ++ + +++ + D + +A K IEK + L +A + Q +L+++L + +SD V WI E+++ + D E L++L+++F+ + + A++V L++ L+ + +P + Q+ L SW + +++ + +L + F D + + I++K + ELG DL S + R+ + D+ A+EA++ LV + +A I Q D V W L++ R LA +D+ F+ + D +W ++ + ++ + A L ++++ E+ A E
Sbjct: 1428 GKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLSNLPR---KLQKHQAFERELRANEGQLRNVTKDGQALVQ-AGNRVPEV---ESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQ-NIEAGTKELQQR--------FKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELEL-DTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAALSQ--ELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEARE 2134 HSP 5 Score: 112.079 bits (279), Expect = 6.474e-24 Identity = 114/498 (22.89%), Postives = 223/498 (44.78%), Query Frame = 1
Query: 1354 AQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEIL---KHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLS 2838
+Q F +A ++W+ + +L G + +V KK E ++ ++ A++ ++ + K++ L E + D +I +V ++ LL+ ER L +++ + E E+ + A ++YG+ + VE+L+ + E S++ + R+E + +R +Q N+ ++ IK KR+ T + + EL D + R++ L K H V+ + D ++ Q I E + + D G DL S+ L RKH+VFE EL + +++ L E L +I P +E I K ++ W L + T +RK KL + Y + D WI+E L + ++ E+L+ + + + + + Q L+ V K+ ++ +++ L +K +E L L D++ + WI+ ++ L + D I ++E L R E FE + + EK + ++
Sbjct: 3148 SQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNLNANEARVEACLERGDRLIQE---------NNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVH-VYDRVADETI--QLINEKDASLISEDYGQDLESIQALGRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKRDETVEAWTDLKEKTAARKNKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTRDETFAKFAANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRREIYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQAIKRIT 3633 HSP 6 Score: 98.2117 bits (243), Expect = 1.267e-19 Identity = 152/808 (18.81%), Postives = 335/808 (41.46%), Query Frame = 1
Query: 1033 WIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTG-EKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKT-----LVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEI--LIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQT----VAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNS 3420
W++ R++ S+ G+ F + T SK VE++D V F + + + ++ I+ W LN A+ RE +L + + FN+ + W+++ M L + +L TV A ++H+ +E ++ E+ + +T + ++++ + ++ + +V D+W+++ Q + R +++ + N + A I + + D + + LL+ H + DIR+ + +E +Q Q N + E+ + H +K+K +L+ L F +A + K + +LG L V+ +L++H FE K + ++K+++G + L+ ++I + N + +A+ D RK L D++++ ++ DD + W+ + R+ GD+ ++ ++ L RK Q++ R N Q+RN + G ++V V ++ + K+++DLL ++ KL A + + + + E L + +D+ + L ++ ++ ESE+T +KV + + +++ G+ N Q I L + + D +R +L +Y F + +WI E + +S +ELG++L ++ ++ +I + I+ + G ++ + +E + Q W+ L++ +R L +++ + +WLG+ + S + A KL+ K+ +
Sbjct: 1044 WMKEKERMIK----SDEGEGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQ-------RQIHQIWQRLNNAKAQREKSLEGA--------SSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHD-------TEFVEVIQLGKQLSDGKPNMAETVAVIERLKAEQDAIHR--GWAEKQKWLLQCVDL-QMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFE-----KSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRI-----AGDE-NYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKD--GQALVQAGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKS-NELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKT 1808 HSP 7 Score: 61.6178 bits (148), Expect = 1.264e-8 Identity = 118/591 (19.97%), Postives = 246/591 (41.62%), Query Frame = 1
Query: 4504 ASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTL-LQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEE-------FKKSCVSLPDEYKGIVKDVEDNFNSLKIICAEKKTEISLFV---IYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQ-------GKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWD-LHRWYCDSQ-FLLECIQEKKSSMEV---------------VNDLGKDPKSVSLLQRKLKNFEKDLLKLD------SDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDK-RDIL 6150
A E+ + ++ T D L + + ++ I F ++CDD WM EK +I +S + E + +F++ + + VD+ ++ +D+ ++ Q+ + + LN + + L +V+ F E W+SEK L L VI + D + ++ + R+ QNLE E+ K+ K + + D ++V+D + ++ ++ + I V ++ ++ ++ + AWI +D+S +D++ L + N +G + + F E+IQ GK A +++V I+ LK+ D +HR + + Q +LL+C+ + + E N+LG V + ++ +FEK L+ D SD + + ++ Y D+ ++ KR+ + D +++L+ K DFH F + +L W+++ T ++ RD+S + L H++ + E+ + E G+ L++ + R PE++S+ ++ + +D+L
Sbjct: 997 ADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMI--KSDEGEGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDK-------IIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVI-TPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKV---LLAWIDSVKDQLNADESARDVETANNLLKKH-------NDLGDD-IRAHDTEFVEVIQLGKQLSDGKPNMAETVAV-------------------IERLKAEQDAIHRGWAEKQKWLLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASK-------DFHKFAAEADDLKVWLQDKT-RIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGN-RVPEVESRVADLNKRWKDLL 1538 HSP 8 Score: 61.2326 bits (147), Expect = 1.939e-8 Identity = 175/929 (18.84%), Postives = 384/929 (41.33%), Query Frame = 1
Query: 2263 IQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLF---DLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDS-DSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVN-NQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEI------LRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNN-KSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHS-----ELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNR--SKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKE 4992
I ++ L + + R L + + + + +CDD E W+ E +R+ + + + + E I + VE ++ R Q S L I + + + R L+ A +EK L+ + L N + D + W++EK L + + D+ ++ L+ R + E EL +KV V L N V N P + VN Q + + W ++ R+ + S+ F + + WI + +K + DE D+E+ ++ N + DI A + + ++ G ++ + + + ++ + D +H+ W ++ L D+ F ++ D + + N+ S E E ++ ++ + A ++ L+ + + ++ +++ +R + K + D + E+++ L+ F +A + K ++D + + N +L +L + +++ F ++ ++E L V K G+ L+ N + ++++ +L++RWK ++++ KL++ E + ++D + E L + N+ +S + + + LE EI + + EL G A HF + N+ + EL + ++ L++ R KL E + + E Q + + P + + +Q + L + +LE + K + + + + L+ QQ+P++ + E L Q++ L + + + A+Q+L D + W+ E+ +++R+ + ++ LL +HK+++ E+ S V + M+ NH ++ ++K ++L++ + Q L L E+ L+ EV WI E+E
Sbjct: 1007 INQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSDEGEGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQR--------LNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLG-NSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWI-DSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQLGKQLSDGKPNMAETVAVIERLKAEQDAIHRGWA-------EKQKWLLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYI--GDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDL--------KVWLQDKTRIAGDENY--RDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGNRVPE-VESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDM-AHGGHFNAQ------NIEAGTKELQQRFKD-LRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPER-EQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLL------TKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQE 1890 HSP 9 Score: 57.7658 bits (138), Expect = 2.045e-7 Identity = 52/188 (27.66%), Postives = 89/188 (47.34%), Query Frame = 1
Query: 5251 ELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSE--TNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVN--DLGKD-PKSVSLLQR------KLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKE 5781
E Y N E+W+V++ +I ++ + KDL L+ + E + K S +++ A KR LI +HP + I D + E W L L++ R + L+ A + +++Y D+ + EK + +VN D G D P + +LLQR +L + D+L L+ + I L L + E
Sbjct: 663 EDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQMSTAGKR---LIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFYTDANEAESWLNEK---IALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKLIKAGICTLELSAAEPE 844
BLAST of Spectrin beta chain vs. Ensembl Zebrafish
Match: sptbn1 (spectrin, beta, non-erythrocytic 1 [Source:ZFIN;Acc:ZDB-GENE-031006-3]) HSP 1 Score: 1285.4 bits (3325), Expect = 0.000e+0 Identity = 803/2341 (34.30%), Postives = 1314/2341 (56.13%), Query Frame = 1
Query: 322 VDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLS-----IANQKIIAEQFLQDCDDEIDWMNEKIDLIR--NRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PD-EYKGIVKD-VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSA-----------SRPMRQVNPSNTNPSTTQSHPNLSSSLPP 7251
+DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + +SAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+SVITYV +YYHYF+ +KA V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +L V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ VL LW+ LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R++ + + A R+ D++ + +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+ RLL +H+ E E+S + L++ + EG+ + D G+ I + D+Q W AL RK +L E +Q+ +D DD + W + R+ +G T+ L++K++ V +YR I+ + QAQ+L + V+++L IE++Y+++ ++ ++ L DAL +Y++ +++D+ WI EK+++L + + +E+LEV++HRFE E E+ +A +V VN ++ L+ +G+P+ + I QD LN W++ D+VD K++ L S N+ +DC +T WIREK K+IES ELG DL VM QR++ M+RD+ AIEAK+ L + D + + AK I +L + WE +++ +R R+ +L + + +F+++LDDF +WL + QT +AS+++P + +EAEKL+ ++ ++E+ E+ ++ +G + + +Q Q++ L+ R+++++ W L+ + E ++ L + +F D +Q E LN QE L + L + + E F+ M ++E + V++ G+ L + N+ DR+Q + ++D+R KKN AA +LK+ L + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K GKQ ++ P + + + L L W EL + K Q L N+ +LF +S + KWL +EGQI +DD +TS+ LKK ++E +++ +E L+ + +L+Q+ D ++++ + KV L+ L +A+++I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ + D + + +Q ++ + + ++ L+ + +E EK + L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ L P+ E G+ + V+ + LK + E++ ++ + + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N+ DELI H A +++ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ +L I +K + +LG+D +V LQR FE D+ L + + + L Y DK + ++ E+++A+RSL + E R+ L+ D F SMVR+L+ W+E+V +E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++TDKR + KW + + L L++EV+Q++RDA AEAW++ QE YL++ LG ++DE L+K+ E FE K T E R + + L+ + + E E P + VQ + R EQ QN L D + G ++N P SP+P +R + S ++ P + P + ++G L+RKH+WE N+KAS+R+WH++Y +++ M F+KD ++ + Y +E+P+ L E V A DY K+ VF++R +G EYLFQ +M W+ AI +A + P Q P+++ T + +++S P
Sbjct: 1 MDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKRSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSVITYVVTYYHYFSKMKALKVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRTELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLQAVEAATKKHEAIETDIAAYEERVQAVVAVARELETENYHDIKRITARKDNVLRLWEYLLELLKARRQRLEMNLSLQRVFQEMLYIMDWMDEMKMLLLSQDYGKHLLGVEDLLQKHALVEADIGIQADRVKAVNNNAQRFA--VDEE---GYKPCDPQVIRDRVAHMEFCYQELTQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEQILSSDDCGKDLTGAVRLLSQHRALEDEMSGRSGHLQHTVREGQAMADAGHFGEAKIRERIADVQAQWAALEQLASVRKTRLEEACSLHQFQADADDVDTWTLDALRIVSTADVGHDEFSTQALVKKHKDASTEVASYRPVIDALHEQAQTLPPEQ-ANSANVSERLAGIEERYKEVSELTRLRKQALQDALALYKMFSEADACELWIDEKEQWLNSMEIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLIHSGHPSEKDIKAQQDKLNTRWSQFRDLVDQKKESLNSALGVQNYHLDCNETKSWIREKTKVIESTQELGNDLTGVMALQRKLTGMERDLAAIEAKLGDLRGEADRLAGEHPDQAKAITGRLAEITAVWEEMKETLRTREESLGEASKLQQFLRELDDFQSWLSRTQTAIASEDMPNTLAEAEKLLAQHEGIKNEINNYEEDYQKMRDMG-EMVTQDQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQIFLRDTKQAEAFLNNQEYVLA---------HTEMPTTLEGAEAAIKKQEDFMTTMDANEDKINGVVEAGRRLASDGNINADRIQERAASIDDRHKKNREAAVELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELQSNKEWLDKIEKEGKQLVSEKPETEAVVKEKLAALQKMWTELETTTQTKAQCLFDANKAELFTQSCADLDKWLVGLEGQIQSDDYG----KDLTSVNILLKKQQMLENQVEVRQREVEELQSQAHVLRQEGKDT----DEVDGRRKVVEQKFQELLDPLLKRKNFLMASREI--HQFNRDVEDEILWVEERMPLATSTDHGNNLQTVQLLIK------KNQTLQKEIQGHQPRCDDIFERSQSILKADSPNVEGIRTRLSDLQGLWSLIMQETEKRHSRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSSVAMLKKHQILEQAVEDYAETVHQLSKTSRGLVAANHPESERIGMRQSQVDKLYAGLKDLSEERRGKLE------ERFRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDGVNRMADELINAGHADAATVAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEILGRILDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQDDAVRLQSAYAGDKADDIQRREGEVLEAWRSLLEACEGRRARLLDTGDKFRFFSMVRDLMLWMEDVIRLIETQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKSLLARKHYASEEIKEKLLQLTDKRKDMIDKWEDRWEWLRLILEVHQFSRDAGVAEAWLLGQEPYLSSRELGQSVDEVEKLIKRH-----------EAFE--KSAATWEER---FSALERLTTLELLEVRRLQEEEERRRKPPSPDPVQA-QDGETQQREGEQIAQN---------GLPSDQDSPRDGVDGEMNGVAERSSKEP-----SPIPSPGADRRGKGSQ----------------SATLPTKGQETPSAQ--LEGFLHRKHEWEGHNKKASSRSWHNVYCVINNHEMGFYKDNKNAGQGIP--YHNEIPISLKEAVCEVAVDYKKKKHVFKLRVTDGNEYLFQAKDDEEMNTWIQAIQNAGSGSSSSEKSETAPSNQSTPASSRAHTLPATVSMTSESSP 2249
BLAST of Spectrin beta chain vs. Ensembl Zebrafish
Match: sptbn2 (spectrin, beta, non-erythrocytic 2 [Source:ZFIN;Acc:ZDB-GENE-030131-787]) HSP 1 Score: 1223.38 bits (3164), Expect = 0.000e+0 Identity = 731/2096 (34.88%), Postives = 1203/2096 (57.40%), Query Frame = 1
Query: 154 LSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXD-HSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKII----AEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRM-----IDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTM 6390
++ E E N ++++FERSRIKALADERE VQKKTFTKW+NS L VT +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VN+ NFT SWR GL F A++HKHR DLIDF + R++ NL AF++AE LG+ LLDPEDVNV PDE+S+ITYVA+YYHYF+ +KA +V KR+ K+L+ +E +Q+I+ Y++L S+LL+WI TI LN RQ +NS+ +Q Q+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KAA+RE+W+++N L+ + + G L V AA +KHEAIETDI AY E + + ++ LE E Y+++ ++ ++ VL LW+ L + L RRE L + + L+ E + + + ++ + + GKHL +VE+LL+ H L+E+DI + +R++ + + A R+ +Q ++ + A+++EK + + + EL R+ L S +WQF+ + E WI+E I++ D G DLSS LL KH+ F E++++ L N + G+ LV VG + + D++ W L ++++ R+ L E + ++Q+ +D +D E WI E R + +G T+ L RK ++ E ++++R I+ + Q SLL + V +L IE++Y++L ++ ++ L AL +YR+ +++ + + W+ EK+++L N +E+LEV++ RF+ E E+ ++ VN +++ L+ + N N I Q+ LNN W+ + + ++ L S + N+ ++C + W++EK K+IES LG DL VM QR++ M+RD+ AI+ K+D L ++ +++ + ++I+ QL + + WE L+ ++ R+ +L + + F++ LDDF WL + QT +AS++ P S +EAE+L+ ++ + ++E+ ++ E+ G + + + D Q + L R+++++ W L + E + L + DA+Q E LN+QE L + S+L E + ++E F+ M + E+ + V++ G+ L+ + N Y D++Q K ++ ER +KN AA KLK+ L LQD +L + EK+ ++S ++ S + +A E+ + + +++++K G+ + P ++ + + L L W EL + K Q L NR +LF +S ++ WL+NI Q+ +DD +TS+ LKK H M + ++ S+ L D S +++ + + D S L+ L Q ++ A QF +D +DEI W+ E++ L + + L Q L ++++++ EI+ ++D + M + + +RA + + +L++ L E E+ L+ Q+F D +E +W+ E+EL +M +KD+Q +++K Q LE +++Y I + S + P+ + ++ V+ + LK + E++ ++ + ++E WI ER +A S + G+D + T+LRD+F F+ +T+ IG +V+ N + DELI+ HP S++ WKD +NE WADLLELIDTR Q+L ++++LHR++ D++ L I+EKK ++ +LG+D +V R+ +E D+ L + + L Y +K + + + + +A+ L+ + R+L L+ + FL+MVR+L+ W+E + +Q++ PRDVS L++ANH+ +K E++++ ++F+ C +GRTL+ H S EI+ K ++ KR + QKW +DHL +++EV Q+ RDA+ AE+W+ QE + LG +DE +L+K+ F+K E++F QL++LTT+
Sbjct: 27 IAAETEWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLGRVTCRIGDLYTDLRDGRMLIRLLEVLSGEQLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRSDLIDFDNLKRSNAHYNLQNAFNVAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDYAIEADQLIEKYETLASELLQWIEQTIVTLNDRQLANSLSAVQNQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEMLAARFDRKAAMRETWLSENQRLVSQDNFGVELGAVEAATRKHEAIETDIQAYGERVAAVEAVARELEAEGYHEVRRVLARRDNVLRLWEYLKELLAARRERLMAHRDLQRLLQELSYIMEWMEDMKSRLQSQDSGKHLHDVEDLLQKHTLVEADISAQAERVKAVQATAKRFAS-NEQSYKPC----DPALVEEKVDLLGRAYGELGQLAADRRVRLDDSRRLWQFLWELGEEAAWIREQEQIISGGDYGKDLSSALHLLSKHEAFRDEMAARYGPLGNSIAGGEALVKEGHVGAPEVTERIKDVRAQWSHLEEASQLREQSLNESVAFHQFQTDANDMEAWILETLRQVSSQEVGHDEFSTQTLARKQREVEEEIQSHRSLIDSLHEQG-SLLPEAYAHSPQVEGRLPAIEQRYEELEGLSSSWRQALDGALALYRMFSEASACQLWVGEKEQWLHNMEIPTKLEDLEVIQQRFDTLEPEMNTLGGRISDVNQVAQQLLGSDNRNKDQIDQTQNQLNNRWSDFQSLANQRKQALESALNIQNYHLECNEIKSWMKEKTKVIESTQSLGNDLAGVMALQRKLTGMERDLEAIQGKLDDLRSEAKKLVSEHPEQEEEIKGQLAEIQEVWEELRATMKRREESLGEASKLQGFLRDLDDFQAWLSRTQTTVASEDTPTSLAEAERLLAQHEAIKNEVDNYKEDYEKMRATGAEVTQGQTDA-QHMFLAQRLQALDTGWHELRRMWESRHCVLAQAFDFQTLLRDAKQAEGFLNSQEYVL---------SHTEMPSSLQGAEEAIKKHEDFLTTMEASEEKINGVVESGRRLVSDGNTYADKIQEKTDSIQERHQKNKQAANELLAKLKDNRELQHFLQDGQELTLWINEKMLTAQDMSYDEARNLHSKWQKHQAFMAELASNKDWLDKIDKEGQVLVKEKPELEQTVSETLSGLQKQWVELENTTQAKAQCLFDANRAELFTQSCSALDSWLQNISSQLQSDD----FGKDLTSVNILLKK---HQMLEHQMDVREKEVQSLQSQALALAQED--SGIVEVDGEQRRVTDRFS-QLQDPLKERRQHLLASKEAHQFNRDLEDEILWVKERMPLATSTDHGKD----LPSVQLLMKKNQTLQKEIQGHQPRIDDIQAHGTNMSPGKESEMDRERRAALDGRLAELRELWALLISETEQRNVRLAEANRAQQFYTDAAEAEAWMGEQELHMMS-EEKAKDEQSALVMVKKHQILEQALEDYAQTIHQLANSSRLMVNSEHPESERITLRQAQVDKLYAGLKDLAEERRGKLQERLRLTQLKREVDDLEQWIAEREVVAGSHELGQDYEHVTMLRDKFREFARDTSTIGQERVDAVNAQADELIESGHPENASVAEWKDGLNEAWADLLELIDTRTQMLAASYELHRFHQDAREALGLIREKKETL-AGAELGRDLNTVQHFLRQHTAYEHDVQALSGQVTQVQDDAARLQKAYAGEKADDIHRHERAVTEAWEGLQSATQTRRLLLLDTVEKFRFLNMVRDLMLWMEGINLQIQSHDSPRDVSSAGLVIANHQDIKSEIETRADSFTACSEMGRTLINNNHYASDEIQEKLDQLQAKRTEINQKWQEKMDHLQIVLEVLQFGRDASMAESWLAGQEPLVRAAELGSNVDEVESLIKRHEAFEKLAAGWEDRFSQLEKLTTL 2090 HSP 2 Score: 88.5817 bits (218), Expect = 1.278e-16 Identity = 45/134 (33.58%), Postives = 73/134 (54.48%), Query Frame = 1
Query: 6841 MKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSS 7242
M+G L RK + E+ N+K++NR+W ++Y +L + + F+KD + Y E+P+ L E V A DY KR VF++R +G EYLFQ +M+ W+ AI S+ + ++ S + P +S S
Sbjct: 2194 MEGILCRKQEMESHNKKSANRSWQNVYCVLRKGSLGFYKDNKSASNGIP--YHGEVPISLGEAVCEVAHDYKKRKHVFKLRLGDGKEYLFQAKDEAEMSSWIRAIQSSMSSSERSPGASRGLSRAMTMPPMSPS 2325
BLAST of Spectrin beta chain vs. Ensembl Zebrafish
Match: sptbn1 (spectrin, beta, non-erythrocytic 1 [Source:ZFIN;Acc:ZDB-GENE-031006-3]) HSP 1 Score: 1219.14 bits (3153), Expect = 0.000e+0 Identity = 729/2034 (35.84%), Postives = 1192/2034 (58.60%), Query Frame = 1
Query: 322 VDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLS-----IANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PD-EYKGIVKD-VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKF 6363
+DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + +SAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+SVITYV +YYHYF+ +KA V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +L V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ VL LW+ LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R++ + + A R+ D++ + +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+ RLL +H+ E E+S + L++ + EG+ + D G+ I + D+Q W AL RK +L E +Q+ +D DD + W + R+ +G T+ L++K++ V +YR I+ + QAQ+L + V+++L IE++Y+++ ++ ++ L DAL +Y++ +++D+ WI EK+++L + + +E+LEV++HRFE E E+ +A +V VN ++ L+ +G+P+ + I QD LN W++ D+VD K++ L S N+ +DC +T WIREK K+IES ELG DL VM QR++ M+RD+ AIEAK+ L + D + + AK I +L + WE +++ +R R+ +L + + +F+++LDDF +WL + QT +AS+++P + +EAEKL+ ++ ++E+ E+ ++ +G + + +Q Q++ L+ R+++++ W L+ + E ++ L + +F D +Q E LN QE L + L + + E F+ M ++E + V++ G+ L + N+ DR+Q + ++D+R KKN AA +LK+ L + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K GKQ ++ P + + + L L W EL + K Q L N+ +LF +S + KWL +EGQI +DD +TS+ LKK ++E +++ +E L+ + +L+Q+ D ++++ + KV L+ L +A+++I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ + D + + +Q ++ + + ++ L+ + +E EK + L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ L P+ E G+ + V+ + LK + E++ ++ + + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N+ DELI H A +++ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ +L I +K + +LG+D +V LQR FE D+ L + + + L Y DK + ++ E+++A+RSL + E R+ L+ D F SMVR+L+ W+E+V +E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++TDKR + KW + + L L++EV+Q++RDA AEAW++ QE YL++ LG ++DE L+K+ F+K+ EE+F
Sbjct: 1 MDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKRSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSVITYVVTYYHYFSKMKALKVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRTELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLQAVEAATKKHEAIETDIAAYEERVQAVVAVARELETENYHDIKRITARKDNVLRLWEYLLELLKARRQRLEMNLSLQRVFQEMLYIMDWMDEMKMLLLSQDYGKHLLGVEDLLQKHALVEADIGIQADRVKAVNNNAQRFA--VDEE---GYKPCDPQVIRDRVAHMEFCYQELTQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEQILSSDDCGKDLTGAVRLLSQHRALEDEMSGRSGHLQHTVREGQAMADAGHFGEAKIRERIADVQAQWAALEQLASVRKTRLEEACSLHQFQADADDVDTWTLDALRIVSTADVGHDEFSTQALVKKHKDASTEVASYRPVIDALHEQAQTLPPEQ-ANSANVSERLAGIEERYKEVSELTRLRKQALQDALALYKMFSEADACELWIDEKEQWLNSMEIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLIHSGHPSEKDIKAQQDKLNTRWSQFRDLVDQKKESLNSALGVQNYHLDCNETKSWIREKTKVIESTQELGNDLTGVMALQRKLTGMERDLAAIEAKLGDLRGEADRLAGEHPDQAKAITGRLAEITAVWEEMKETLRTREESLGEASKLQQFLRELDDFQSWLSRTQTAIASEDMPNTLAEAEKLLAQHEGIKNEINNYEEDYQKMRDMG-EMVTQDQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQIFLRDTKQAEAFLNNQEYVLA---------HTEMPTTLEGAEAAIKKQEDFMTTMDANEDKINGVVEAGRRLASDGNINADRIQERAASIDDRHKKNREAAVELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELQSNKEWLDKIEKEGKQLVSEKPETEAVVKEKLAALQKMWTELETTTQTKAQCLFDANKAELFTQSCADLDKWLVGLEGQIQSDDYG----KDLTSVNILLKKQQMLENQVEVRQREVEELQSQAHVLRQEGKDT----DEVDGRRKVVEQKFQELLDPLLKRKNFLMASREI--HQFNRDVEDEILWVEERMPLATSTDHGNNLQTVQLLIK------KNQTLQKEIQGHQPRCDDIFERSQSILKADSPNVEGIRTRLSDLQGLWSLIMQETEKRHSRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSSVAMLKKHQILEQAVEDYAETVHQLSKTSRGLVAANHPESERIGMRQSQVDKLYAGLKDLSEERRGKLE------ERFRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDGVNRMADELINAGHADAATVAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEILGRILDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQDDAVRLQSAYAGDKADDIQRREGEVLEAWRSLLEACEGRRARLLDTGDKFRFFSMVRDLMLWMEDVIRLIETQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKSLLARKHYASEEIKEKLLQLTDKRKDMIDKWEDRWEWLRLILEVHQFSRDAGVAEAWLLGQEPYLSSRELGQSVDEVEKLIKRHEAFEKSAATWEERF 1993 HSP 2 Score: 125.946 bits (315), Expect = 5.228e-28 Identity = 132/636 (20.75%), Postives = 276/636 (43.40%), Query Frame = 1
Query: 4612 QFLQDCDDEIDWMNEKIDLIRNR--SKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINS---KDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPDEYKGI------VKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTK-HIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQ-WARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLN----TDRQFINEALINIEQTAE 6468
+F + +E W+ EK ++ + K + LL +H+++++E+ RS + ++E Q M D H A + + + ++ L + + L ++ +F D +V +W LD + +V + D+ + +++K ++ E+ +Y P I+ + +LP E + +E+ + + + +K + + + E WI E+ + S + + L+ +++ RF E N +S+V N+ +LI HP I +D++N W+ +L+D + + L SA + ++ D I+EK +E +LG D V LQRKL E+DL +++ + + ++ L + D+ + + E+ + +++ L R+ + E + FL + + W+ + P ++ E LLA H +K E+++ EE++ ++G + + + + ++ + + + + L + W N + LS YQ + RD AEA++ +QE L + + TL+ A +KK +E F +TTM+ K+N R+ ++ IN ++ E
Sbjct: 563 KFFWEMAEEEGWIREKEQILSSDDCGKDLTGAVRLLS------QHRALEDEMSGRSGHLQHTVREGQAMADAGHFGEAKIRERIADVQAQWAALEQLASVRKTRLEEACSLHQFQADADDVDTWT----LDALRIVSTADVGHDEFSTQALVKKHKDASTEVASYRPVIDALHEQAQTLPPEQANSANVSERLAGIEERYKEVSELTRLRKQALQDALALYKMFSEADACELWIDEKEQWLNSMEIPEKLEDLEVIQHRFESLEPEMNN-QASRVAVVNQIARQLIHSGHPSEKDIKAQQDKLNTRWSQFRDLVDQKKESLNSALGVQNYHLDCNETKSWIREKTKVIESTQELGNDLTGVMALQRKLTGMERDLAAIEAKLGDLRGEADRLAGEH-PDQAKAITGRLAEITAVWEEMKETLRTREESLGEASKLQQFLRELDDFQSWLSRTQTAIASEDMPNTLAEAEKLLAQHEGIKNEINNYEEDYQKMRDMGEMVTQDQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLS-QSHAYQIFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKK-----------QEDF-----MTTMDANEDKINGVVEAGRRLASDGNINADRIQE 1169
BLAST of Spectrin beta chain vs. Ensembl Zebrafish
Match: sptb (spectrin, beta, erythrocytic [Source:ZFIN;Acc:ZDB-GENE-000906-1]) HSP 1 Score: 1208.36 bits (3125), Expect = 0.000e+0 Identity = 735/2110 (34.83%), Postives = 1211/2110 (57.39%), Query Frame = 1
Query: 133 SSDYQNA--------------LSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDI-----QFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYE-QLETQ-VKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIR--NRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRM--IDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK---DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKF 6363
++DY NA LSDE E+ N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY+DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RL LGLIWTIILRFQ+QDI Q D+ +SAKDALLLWCQMKTAGYP++NI NFT SW+ G+ F ALIHKHRPDL+D+ + R++ +NL AF++AE LG+ LLDPEDV PDE+S+ITYV ++YHYF+ +KA +V KR+ K+L+Q +E E+MI+ Y++L S LL WI TI +LN R+ +NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AEY RE LR EL+RQEKL +A++F++KAA+RE+W+ +N L+ + + G +LP V AA KKH+AIETDI AYEE + L +S LE E Y+D I K+ +L LW L + L RR LD L + + E + + + + + ++GKHL+EVE+LL+ H L+E+DI +R++ + A ++F + D + + +I+++ + EL +RK L+ S +W F+ + + E WI+E I ++ D G DL+SV L KH VFE EL+++R +L+ + EG++++ I +G + + ND+Q W+ L + RK L + ++Q+ D DD + W+ + R +G T+ L++K++ + I+ + QA + L + + + +L+ I Y +LL ++ Q+KL D + +Y + +++D+ W+ +K+ +L +++E+LE++++R + E+ +V +VN ++ L + +P + + + Q LN W +V+ K+ + S N+ +DC +T WI+EK ++IES +LG DL +V+ QR++ M+RD+ AI+ K+D L + ++++ + +A DI + + + W+ L++ ++DR+ +L + + F+Q +DDF WL + Q +AS+++P+ EAE+L+N +++ R +M E+ G ++ ++D Q+ +L+ R+E +++ W L+ + + ++ L++ L F DA+Q + ILN QE L + ++ +T L + + ++E F+ M ++++ + L+ G+ L+ NLY ++++K +++ER KKN A+ KLK+ L LQ+ DL + EK+ + S ++ S + +A E+ + + + ++K G++ P F+ + D L L+ W +L +EK + L NR +LF++S + KWL ++ Q+ D E + +TS LKK H + + L++ E ++Q + + E ++E Q ++ L PL + QF +D DEI W+NE++ + + ++T+ LL+ +++S++ EI ++D +++ +RM E + + + + +L+ L EEM K + L Q++ D + +WI E+EL ++ + +KD+Q ++++ L+ + +Y I++ + PD + I++ V+ + LK + ++K ++ + +++E WI ER +A S + G+DLD T+LRD+F F+ ET +G +V+ N+ DELI+G H + +++ WKD +NE WADLLELIDTR QLL S++DL +++ D + L+ I+EKK+ E+ DLG+D R FE+D+ L + + L Y D+ + +E+++A++ L R+ E AD F +MVR+L+ W+E + Q+E + KPRDVS +ELL+ H+ ++ E++++ F+ C+ LG+ LL KH S EIK K ++ +KR + KW + D L L++EV Q+ARDA+ AEAW+I+QE Y+ ++++G T+DE LLK+ F+K+ EE+F
Sbjct: 7 TTDYDNAEITQQYSRINTRFELSDE-ELDNDNSSARLFERSRIKALADEREAVQKKTFTKWVNSILARVSCRISDLYLDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLILGLIWTIILRFQIQDIIVETGQADQTGRQETRSAKDALLLWCQMKTAGYPNINITNFTTSWKDGMAFNALIHKHRPDLVDYGNLKRSNPTHNLQQAFNVAEKKLGVTKLLDPEDVFTENPDEKSIITYVVAFYHYFSKMKALAVEGKRIGKVLDQAIETEKMIEKYETLSSDLLTWIEQTIVVLNNRKLANSLTGVQQQLQAFNSYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPKEGALVSDINKAWERLEKAEYDRERVLRDELIRQEKLEQMARRFDRKAAMRETWLMENQRLVSQDNFGYDLPAVEAAKKKHDAIETDIAAYEERVQALVALSKELESERYHDAKRIDARKDNILRLWDYLQELLKARRGRLDKNLTLQRIFQEMLHIISWMDEMKGRLLSPDFGKHLLEVEDLLQKHSLVEADIAVQAERVKSANAAA---LKFANGD---SYKPCDPQVIRDRVQHLDLCYQELCALAAQRKARLEQSRRLWNFLWEIAELESWIREREQIFSSLDYGKDLTSVLILQSKHSVFEDELAARRDNLKQVMDEGESMIQIKHLGSPKVQQRMNDVQRQWQQLEELAAFRKQNLQDTQRFFQFQGDADDLKAWLVDAMRQMSSDDVGHDEYTTQRLLKKHRDLRDEAAKNGATIDALSKQANA-LPEELRNTPDIQGRLNDIRDMYIELLTLSDLRQKKLDDTMALYTIFSETDACELWMGQKETWLVGLETPENLEDLEIVQNRLSILAQEMGNMQTRVDNVNKAAKQLEDSRHPQTKQVKDCQIRLNKRWEAFKAMVEDKKHRVDSALSLHNYDLDCDETESWIKEKTRVIESTQDLGNDLAAVITIQRKLFGMERDLAAIQDKLDSLRDEAQKLVKEHPENASDILARQEELDAAWDTLKRTLKDREDSLGEVSKLQTFLQDMDDFQAWLFKSQKAVASEDMPDGLPEAEQLLNLHDALRHDMDGHEEDYHRVKDTGAAVIQGQEDDPQYQQLEQRLEGLDKGWGELHKMWDSRKNFLDQGLGFQQFMRDAKQADAILNNQEYTL-----AHVDKPDT----LDGAEKALKKHEDFVTTMDANKEKILSTLETGQRLVDSENLYSGKVKDKMSSIEERNKKNQDKAKEVSGKLKDNRELQHFLQNTQDLTLWINEKMLTAQDTSYDEARNLHSKWQKHQAFMAELASNKDWLHNIDKEGQELMESKPEFEPIVKDRLAKLHELWDKLESTTQEKARLLFDANRSELFDQSLADLKKWLAELQQQLQGDVEEE--VKDLTSANILLKK---HQITENQVRDRARELEELQEAVEQHGSLREDQPELEIEQQNLQRDFQKLLTPLSQRKGKLEAAKAVHQFFRDLADEILWVNERLPMAMSDDHGNNLQTVQLLLK------KNQSLQKEIDGHQPRIDEVLERGRRMAAAAEGSPEEERMSEEMKKLQVVWAQLQEEMAKRRERLYGSNEAQQYYNDADDSEAWIGEQELYMIADEM-AKDEQSAMIMLKRHLVLKQTVDDYAYSIQQLADRAQKMLAEEHPD-GEAIIRRQGQVDKQYAGLKELAEDRKKKLDHTYHHFLLSREVEDLEQWIAERDVVASSQEMGQDLDHVTILRDKFREFARETGTVGQERVDTVNRIIDELIEGGHSESATLAEWKDGVNESWADLLELIDTRAQLLTSSYDLLKYFYDGKELVGHIEEKKN--ELPEDLGEDFSKAESFHRMHAAFERDISSLGKQVKQFQETAARLHAQYAGDQATAIQATEKEVVEAWKGLLDACAGRRKQLEETADKFRFFTMVRDLMAWMESILQQIETQEKPRDVSSVELLMKYHQGIRAEIETRGPKFNQCVQLGQALLERKHKDSAEIKEKLMQLVEKRKEMMLKWDDRWDWLRLLLEVCQFARDASVAEAWLIAQEPYVASKDVGQTVDEVEKLLKRHEAFEKSTATWEERF 2084 HSP 2 Score: 91.6633 bits (226), Expect = 1.176e-17 Identity = 54/171 (31.58%), Postives = 88/171 (51.46%), Query Frame = 1
Query: 6751 PVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVL----CEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPP 7251
P ++ V+ + A+ P + + P VLM+G L RKH+ E N+KA NR+W++LY +L ++ +KD + F + E PL L CE++ +Y K+ VF++R +G+EYLFQ ++ W AI A++ Q+ PS + + SLPP
Sbjct: 2176 PSTSIQVTKETEKAASLPTESTQVQP--VLMEGTLARKHELEGPNKKAPNRSWNNLYCVLKPGHLSIYKDAKSFSHSVT--FHGEEPLTLTNSSCEILT----NYKKKKQVFKLRLGDGSEYLFQCKDEEELQNWTQAIEQAAQV--QIEEPVAGPSGVK-----ALSLPP 2331
BLAST of Spectrin beta chain vs. Ensembl Zebrafish
Match: sptb (spectrin, beta, erythrocytic [Source:ZFIN;Acc:ZDB-GENE-000906-1]) HSP 1 Score: 1208.36 bits (3125), Expect = 0.000e+0 Identity = 735/2110 (34.83%), Postives = 1211/2110 (57.39%), Query Frame = 1
Query: 133 SSDYQNA--------------LSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDI-----QFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYE-QLETQ-VKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIR--NRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRM--IDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK---DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKF 6363
++DY NA LSDE E+ N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY+DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RL LGLIWTIILRFQ+QDI Q D+ +SAKDALLLWCQMKTAGYP++NI NFT SW+ G+ F ALIHKHRPDL+D+ + R++ +NL AF++AE LG+ LLDPEDV PDE+S+ITYV ++YHYF+ +KA +V KR+ K+L+Q +E E+MI+ Y++L S LL WI TI +LN R+ +NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AEY RE LR EL+RQEKL +A++F++KAA+RE+W+ +N L+ + + G +LP V AA KKH+AIETDI AYEE + L +S LE E Y+D I K+ +L LW L + L RR LD L + + E + + + + + ++GKHL+EVE+LL+ H L+E+DI +R++ + A ++F + D + + +I+++ + EL +RK L+ S +W F+ + + E WI+E I ++ D G DL+SV L KH VFE EL+++R +L+ + EG++++ I +G + + ND+Q W+ L + RK L + ++Q+ D DD + W+ + R +G T+ L++K++ + I+ + QA + L + + + +L+ I Y +LL ++ Q+KL D + +Y + +++D+ W+ +K+ +L +++E+LE++++R + E+ +V +VN ++ L + +P + + + Q LN W +V+ K+ + S N+ +DC +T WI+EK ++IES +LG DL +V+ QR++ M+RD+ AI+ K+D L + ++++ + +A DI + + + W+ L++ ++DR+ +L + + F+Q +DDF WL + Q +AS+++P+ EAE+L+N +++ R +M E+ G ++ ++D Q+ +L+ R+E +++ W L+ + + ++ L++ L F DA+Q + ILN QE L + ++ +T L + + ++E F+ M ++++ + L+ G+ L+ NLY ++++K +++ER KKN A+ KLK+ L LQ+ DL + EK+ + S ++ S + +A E+ + + + ++K G++ P F+ + D L L+ W +L +EK + L NR +LF++S + KWL ++ Q+ D E + +TS LKK H + + L++ E ++Q + + E ++E Q ++ L PL + QF +D DEI W+NE++ + + ++T+ LL+ +++S++ EI ++D +++ +RM E + + + + +L+ L EEM K + L Q++ D + +WI E+EL ++ + +KD+Q ++++ L+ + +Y I++ + PD + I++ V+ + LK + ++K ++ + +++E WI ER +A S + G+DLD T+LRD+F F+ ET +G +V+ N+ DELI+G H + +++ WKD +NE WADLLELIDTR QLL S++DL +++ D + L+ I+EKK+ E+ DLG+D R FE+D+ L + + L Y D+ + +E+++A++ L R+ E AD F +MVR+L+ W+E + Q+E + KPRDVS +ELL+ H+ ++ E++++ F+ C+ LG+ LL KH S EIK K ++ +KR + KW + D L L++EV Q+ARDA+ AEAW+I+QE Y+ ++++G T+DE LLK+ F+K+ EE+F
Sbjct: 7 TTDYDNAEITQQYSRINTRFELSDE-ELDNDNSSARLFERSRIKALADEREAVQKKTFTKWVNSILARVSCRISDLYLDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLILGLIWTIILRFQIQDIIVETGQADQTGRQETRSAKDALLLWCQMKTAGYPNINITNFTTSWKDGMAFNALIHKHRPDLVDYGNLKRSNPTHNLQQAFNVAEKKLGVTKLLDPEDVFTENPDEKSIITYVVAFYHYFSKMKALAVEGKRIGKVLDQAIETEKMIEKYETLSSDLLTWIEQTIVVLNNRKLANSLTGVQQQLQAFNSYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPKEGALVSDINKAWERLEKAEYDRERVLRDELIRQEKLEQMARRFDRKAAMRETWLMENQRLVSQDNFGYDLPAVEAAKKKHDAIETDIAAYEERVQALVALSKELESERYHDAKRIDARKDNILRLWDYLQELLKARRGRLDKNLTLQRIFQEMLHIISWMDEMKGRLLSPDFGKHLLEVEDLLQKHSLVEADIAVQAERVKSANAAA---LKFANGD---SYKPCDPQVIRDRVQHLDLCYQELCALAAQRKARLEQSRRLWNFLWEIAELESWIREREQIFSSLDYGKDLTSVLILQSKHSVFEDELAARRDNLKQVMDEGESMIQIKHLGSPKVQQRMNDVQRQWQQLEELAAFRKQNLQDTQRFFQFQGDADDLKAWLVDAMRQMSSDDVGHDEYTTQRLLKKHRDLRDEAAKNGATIDALSKQANA-LPEELRNTPDIQGRLNDIRDMYIELLTLSDLRQKKLDDTMALYTIFSETDACELWMGQKETWLVGLETPENLEDLEIVQNRLSILAQEMGNMQTRVDNVNKAAKQLEDSRHPQTKQVKDCQIRLNKRWEAFKAMVEDKKHRVDSALSLHNYDLDCDETESWIKEKTRVIESTQDLGNDLAAVITIQRKLFGMERDLAAIQDKLDSLRDEAQKLVKEHPENASDILARQEELDAAWDTLKRTLKDREDSLGEVSKLQTFLQDMDDFQAWLFKSQKAVASEDMPDGLPEAEQLLNLHDALRHDMDGHEEDYHRVKDTGAAVIQGQEDDPQYQQLEQRLEGLDKGWGELHKMWDSRKNFLDQGLGFQQFMRDAKQADAILNNQEYTL-----AHVDKPDT----LDGAEKALKKHEDFVTTMDANKEKILSTLETGQRLVDSENLYSGKVKDKMSSIEERNKKNQDKAKEVSGKLKDNRELQHFLQNTQDLTLWINEKMLTAQDTSYDEARNLHSKWQKHQAFMAELASNKDWLHNIDKEGQELMESKPEFEPIVKDRLAKLHELWDKLESTTQEKARLLFDANRSELFDQSLADLKKWLAELQQQLQGDVEEE--VKDLTSANILLKK---HQITENQVRDRARELEELQEAVEQHGSLREDQPELEIEQQNLQRDFQKLLTPLSQRKGKLEAAKAVHQFFRDLADEILWVNERLPMAMSDDHGNNLQTVQLLLK------KNQSLQKEIDGHQPRIDEVLERGRRMAAAAEGSPEEERMSEEMKKLQVVWAQLQEEMAKRRERLYGSNEAQQYYNDADDSEAWIGEQELYMIADEM-AKDEQSAMIMLKRHLVLKQTVDDYAYSIQQLADRAQKMLAEEHPD-GEAIIRRQGQVDKQYAGLKELAEDRKKKLDHTYHHFLLSREVEDLEQWIAERDVVASSQEMGQDLDHVTILRDKFREFARETGTVGQERVDTVNRIIDELIEGGHSESATLAEWKDGVNESWADLLELIDTRAQLLTSSYDLLKYFYDGKELVGHIEEKKN--ELPEDLGEDFSKAESFHRMHAAFERDISSLGKQVKQFQETAARLHAQYAGDQATAIQATEKEVVEAWKGLLDACAGRRKQLEETADKFRFFTMVRDLMAWMESILQQIETQEKPRDVSSVELLMKYHQGIRAEIETRGPKFNQCVQLGQALLERKHKDSAEIKEKLMQLVEKRKEMMLKWDDRWDWLRLLLEVCQFARDASVAEAWLIAQEPYVASKDVGQTVDEVEKLLKRHEAFEKSTATWEERF 2084 HSP 2 Score: 91.6633 bits (226), Expect = 1.176e-17 Identity = 54/171 (31.58%), Postives = 88/171 (51.46%), Query Frame = 1
Query: 6751 PVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVL----CEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPP 7251
P ++ V+ + A+ P + + P VLM+G L RKH+ E N+KA NR+W++LY +L ++ +KD + F + E PL L CE++ +Y K+ VF++R +G+EYLFQ ++ W AI A++ Q+ PS + + SLPP
Sbjct: 2176 PSTSIQVTKETEKAASLPTESTQVQP--VLMEGTLARKHELEGPNKKAPNRSWNNLYCVLKPGHLSIYKDAKSFSHSVT--FHGEEPLTLTNSSCEILT----NYKKKKQVFKLRLGDGSEYLFQCKDEEELQNWTQAIEQAAQV--QIEEPVAGPSGVK-----ALSLPP 2331
BLAST of Spectrin beta chain vs. Ensembl Xenopus
Match: SPTBN1 (spectrin beta, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11275]) HSP 1 Score: 1355.12 bits (3506), Expect = 0.000e+0 Identity = 844/2400 (35.17%), Postives = 1371/2400 (57.12%), Query Frame = 1
Query: 163 EDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQN--PDKASKYEQLETQVKVTMDGLSVPL--ESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEIS----LFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFE-----------QLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQ------TFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPS-TTQSHPNLS--SSLPP 7251
+DE N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE ++ + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R+ + + A R+ + + +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RL KHK FE E+S + L + EG+ ++ G E I + DIQ W L + RK +L + YQ+ +D DD + W+ + R+ +G T+ L++K++ E + NYR I+ + QA + L + V +L IE++Y++L ++A ++ L DALT+Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ +G+P+ + I QD LN W++ ++VD +D L S N+ ++C +T WIREK K+IES ELG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L ++ WE ++ +++R+ +L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + +F D +Q E LN QE Y++ + L NN +++ + E F+ M + E+ + V+ G+ L+ + N+ D+++ K ++D R KKN A + +LK+ + + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q A+ P + + + + L++ W EL + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK +++ +KK +E L+ ++ L Q+ D+ Q+ V+V L PL K +A+++I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ + D + + ++ ++D++ L + + L+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ LF + + ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N D+LI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A+++L + R+L ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW+ QE YL++ +G ++DE L+K+ F+K+ +E+F +++RL E R +K T E+ ++E+ T E + I Q++ R + D+ +E+ + Q+ +S++S P P SP K QP +A+ PA T+ +P + +G L+RKH+WE N+KAS+R+WH++Y +++ M F+KD ++ Y +E+P L E V A DY K+ VF+++ +G EYLFQ +M W+ AI +A + T S +TQS P S +LP
Sbjct: 25 DDEWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYADLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLIGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVLAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLKARRLRLEMNLGLQKVFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQADRVRAVNASAQRFATGGE-----GYKPCDPQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEQILSSDDYGKDLTSVVRLYCKHKAFEDEMSGRSGHLLQTIKEGEEMIAEDHFGSEKIRERIKDIQEQWANLEHLSAIRKKRLEDTTSSYQFQADADDVDAWMLDILRIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRSTIDALHEQA-AALPEERFNSTDVQNRLSGIEERYKELAELARLRKQALQDALTLYKMFSEADACELWIVEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLIHSGHPSEKEIKAQQDKLNTRWSQFRELVDKTKDALSSALSIQNYHLECNETKSWIREKTKVIESTQELGNDLAGVMALQRKLTGMERDLAAIEAKLTDLQKEAEKLEAEHPDQAQAIMDRLAEINNVWEEMKTTLKNREESLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLAEAEKLLTQHENIKNEINNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQSLLSQSHAYQLFLRDTKQAEAFLNNQE-YVLAHTE-LPNNLEAAEA-------AIKTQEDFMTTMDASEEKINAVVDTGRRLVNDENINSDKIEEKVDSIDSRHKKNRAGANDLLMRLKDNREMQKFLQDCQELSLWINEKMLTARDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGNQLIAEKPETEAIVKEKMSALHAMWEELESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQMLENQMDVRKKEVEELRSQAQALSQEGKSTDEVDGQRQV---VEVRFIELLAPLNERKKYLLASKEI--HQFNRDVEDEILWVEERMPLATSTDHGHNLQTVQLLMK------KNQTLQKEIQGHQHRNDDIFERSKMILDDSSLNAEAITQRLADLQALWSLLIEETEKRHRRLEESHRAQQYYFDGAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVAEGHPESERISMRQSQVDKLYAGLKDLSEERRGKLDERQRLFQLNREV----DDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGHIGQERVDSVNHMADDLINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASFELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRESEVLEAWKALLDACDGRRLRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLFGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRLQEEEERKRKPPTP--------------------ELSPKLSEDGSPQQWDGTKEGEQISQNGLPSDQESPRMAENADT-----NELVNGSTEQRSSSKES--SPIP-----SPTADRKSKSGMQPQ----------------TAATLPAKTQEMPSAQ--FEGFLHRKHEWEGHNKKASSRSWHNVYCVINNQEMGFYKDSKNAASGIA--YHNEIPANLKEAVCEVATDYKKKKHVFKLKLNDGNEYLFQAKDDEEMNTWIQAITNA------ITSDKTEVSLSTQSTPASSRAQTLPA 2328
BLAST of Spectrin beta chain vs. Ensembl Xenopus
Match: SPTBN1 (spectrin beta, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11275]) HSP 1 Score: 1352.04 bits (3498), Expect = 0.000e+0 Identity = 839/2398 (34.99%), Postives = 1362/2398 (56.80%), Query Frame = 1
Query: 163 EDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPL--ESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEIS----LFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFE-----------QLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQ------TFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPS-TTQSHPNLS--SSLPP 7251
+DE N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE ++ + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R+ + + A R+ + + +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RL KHK FE E+S + L + EG+ ++ G E I + DIQ W L + RK +L + YQ+ +D DD + W+ + R+ +G T+ L++K++ E + NYR I+ + QA + L + V +L IE++Y++L ++A ++ L DALT+Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ +G+P+ + I QD LN W++ ++VD +D L S N+ ++C +T WIREK K+IES ELG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L ++ WE ++ +++R+ +L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + +F D +Q E LN QE Y++ + L NN +++ + E F+ M + E+ + V+ G+ L+ + N+ D+++ K ++D R KKN A + +LK+ + + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q A+ P + + + + L++ W EL + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK N + + + ++ D+ Q+ V+V L PL K +A+++I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ + D + + ++ ++D++ L + + L+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ LF + + ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N D+LI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A+++L + R+L ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW+ QE YL++ +G ++DE L+K+ F+K+ +E+F +++RL E R +K T E+ ++E+ T E + I Q++ R + D+ +E+ + Q+ +S++S P P SP K QP +A+ PA T+ +P + +G L+RKH+WE N+KAS+R+WH++Y +++ M F+KD ++ Y +E+P L E V A DY K+ VF+++ +G EYLFQ +M W+ AI +A + T S +TQS P S +LP
Sbjct: 25 DDEWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYADLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLIGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVLAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLKARRLRLEMNLGLQKVFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQADRVRAVNASAQRFATGGE-----GYKPCDPQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEQILSSDDYGKDLTSVVRLYCKHKAFEDEMSGRSGHLLQTIKEGEEMIAEDHFGSEKIRERIKDIQEQWANLEHLSAIRKKRLEDTTSSYQFQADADDVDAWMLDILRIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRSTIDALHEQA-AALPEERFNSTDVQNRLSGIEERYKELAELARLRKQALQDALTLYKMFSEADACELWIVEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLIHSGHPSEKEIKAQQDKLNTRWSQFRELVDKTKDALSSALSIQNYHLECNETKSWIREKTKVIESTQELGNDLAGVMALQRKLTGMERDLAAIEAKLTDLQKEAEKLEAEHPDQAQAIMDRLAEINNVWEEMKTTLKNREESLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLAEAEKLLTQHENIKNEINNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQSLLSQSHAYQLFLRDTKQAEAFLNNQE-YVLAHTE-LPNNLEAAEA-------AIKTQEDFMTTMDASEEKINAVVDTGRRLVNDENINSDKIEEKVDSIDSRHKKNRAGANDLLMRLKDNREMQKFLQDCQELSLWINEKMLTARDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGNQLIAEKPETEAIVKEKMSALHAMWEELESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQVENGLCWRTRW----------IQEGKSTDEVDGQRQV---VEVRFIELLAPLNERKKYLLASKEI--HQFNRDVEDEILWVEERMPLATSTDHGHNLQTVQLLMK------KNQTLQKEIQGHQHRNDDIFERSKMILDDSSLNAEAITQRLADLQALWSLLIEETEKRHRRLEESHRAQQYYFDGAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVAEGHPESERISMRQSQVDKLYAGLKDLSEERRGKLDERQRLFQLNREV----DDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGHIGQERVDSVNHMADDLINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASFELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRESEVLEAWKALLDACDGRRLRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLFGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRLQEEEERKRKPPTP--------------------ELSPKLSEDGSPQQWDGTKEGEQISQNGLPSDQESPRMAENADT-----NELVNGSTEQRSSSKES--SPIP-----SPTADRKSKSGMQPQ----------------TAATLPAKTQEMPSAQ--FEGFLHRKHEWEGHNKKASSRSWHNVYCVINNQEMGFYKDSKNAASGIA--YHNEIPANLKEAVCEVATDYKKKKHVFKLKLNDGNEYLFQAKDDEEMNTWIQAITNA------ITSDKTEVSLSTQSTPASSRAQTLPA 2316
BLAST of Spectrin beta chain vs. Ensembl Xenopus
Match: SPTBN1 (spectrin beta, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11275]) HSP 1 Score: 1349.34 bits (3491), Expect = 0.000e+0 Identity = 830/2343 (35.42%), Postives = 1345/2343 (57.41%), Query Frame = 1
Query: 163 EDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQN--PDKASKYEQLETQVKVTMDGLSVPL--ESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDM 7134
+DE N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE ++ + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R+ + + A R+ + + +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RL KHK FE E+S + L + EG+ ++ G E I + DIQ W L + RK +L + YQ+ +D DD + W+ + R+ +G T+ L++K++ E + NYR I+ + QA + L + V +L IE++Y++L ++A ++ L DALT+Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ +G+P+ + I QD LN W++ ++VD +D L S N+ ++C +T WIREK K+IES ELG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L ++ WE ++ +++R+ +L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + +F D +Q E LN QE Y++ + L NN +++ + E F+ M + E+ + V+ G+ L+ + N+ D+++ K ++D R KKN A + +LK+ + + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q A+ P + + + + L++ W EL + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK +++ +KK +E L+ ++ L Q+ D+ Q+ V+V L PL K +A+++I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ + D + + ++ ++D++ L + + L+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N D+LI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A+++L + R+L ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW+ QE YL++ +G ++DE L+K+ F+K+ +E+F L+RLTT+ L F++ TA+ ++ + EN T E ++ S +Q S K++ P P SP K QP +A+ PA T+ +P + +G L+RKH+WE N+KAS+R+WH++Y +++ M F+KD ++ Y +E+P L E V A DY K+ VF+++ +G EYLFQ V +
Sbjct: 25 DDEWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYADLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLIGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVLAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLKARRLRLEMNLGLQKVFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQADRVRAVNASAQRFATGGE-----GYKPCDPQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEQILSSDDYGKDLTSVVRLYCKHKAFEDEMSGRSGHLLQTIKEGEEMIAEDHFGSEKIRERIKDIQEQWANLEHLSAIRKKRLEDTTSSYQFQADADDVDAWMLDILRIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRSTIDALHEQA-AALPEERFNSTDVQNRLSGIEERYKELAELARLRKQALQDALTLYKMFSEADACELWIVEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLIHSGHPSEKEIKAQQDKLNTRWSQFRELVDKTKDALSSALSIQNYHLECNETKSWIREKTKVIESTQELGNDLAGVMALQRKLTGMERDLAAIEAKLTDLQKEAEKLEAEHPDQAQAIMDRLAEINNVWEEMKTTLKNREESLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLAEAEKLLTQHENIKNEINNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQSLLSQSHAYQLFLRDTKQAEAFLNNQE-YVLAHTE-LPNNLEAAEA-------AIKTQEDFMTTMDASEEKINAVVDTGRRLVNDENINSDKIEEKVDSIDSRHKKNRAGANDLLMRLKDNREMQKFLQDCQELSLWINEKMLTARDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGNQLIAEKPETEAIVKEKMSALHAMWEELESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQMLENQMDVRKKEVEELRSQAQALSQEGKSTDEVDGQRQV---VEVRFIELLAPLNERKKYLLASKEI--HQFNRDVEDEILWVEERMPLATSTDHGHNLQTVQLLMK------KNQTLQKEIQGHQHRNDDIFERSKMILDDSSLNAEAITQRLADLQALWSLLIEETEKRHRRLEESHRAQQYYFDGAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVAEGHPESERISMRQSQVDKLYAGLKDLSEERRGKLD------ERQRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGHIGQERVDSVNHMADDLINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASFELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRESEVLEAWKALLDACDGRRLRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLFGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTV------LTLCFSFLSTNSTRCSFTADDPETAVM--MAENADTNE--------------------LVNGSTEQRSSSKESS-------------PIP-----SPTADRKSKSGMQPQ----------------TAATLPAKTQEMPSAQ--FEGFLHRKHEWEGHNKKASSRSWHNVYCVINNQEMGFYKDSKNAASGIA--YHNEIPANLKEAVCEVATDYKKKKHVFKLKLNDGNEYLFQAKDDVSI 2261
BLAST of Spectrin beta chain vs. Ensembl Xenopus
Match: SPTBN1 (spectrin beta, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11275]) HSP 1 Score: 1343.56 bits (3476), Expect = 0.000e+0 Identity = 831/2349 (35.38%), Postives = 1344/2349 (57.22%), Query Frame = 1
Query: 163 EDEVQYANVTSKVFERSRIKALA------DERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQN--PDKASKYEQLETQVKVTMDGLSVPL--ESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDM 7134
+DE N ++++FERSRIKALA DERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE ++ + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R+ + + A R+ + + +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RL KHK FE E+S + L + EG+ ++ G E I + DIQ W L + RK +L + YQ+ +D DD + W+ + R+ +G T+ L++K++ E + NYR I+ + QA + L + V +L IE++Y++L ++A ++ L DALT+Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ +G+P+ + I QD LN W++ ++VD +D L S N+ ++C +T WIREK K+IES ELG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L ++ WE ++ +++R+ +L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + +F D +Q E LN QE Y++ + L NN +++ + E F+ M + E+ + V+ G+ L+ + N+ D+++ K ++D R KKN A + +LK+ + + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q A+ P + + + + L++ W EL + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK +++ +KK +E L+ ++ L Q+ D+ Q+ V+V L PL K +A+++I QF +D +DEI W+ E++ L + ++T+ Q L ++++++ EI+ + D + + ++ ++D++ L + + L+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N D+LI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A+++L + R+L ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW+ QE YL++ +G ++DE L+K+ F+K+ +E+F L+RLTT+ L F++ TA+ ++ + EN T E ++ S +Q S K++ P P SP K QP +A+ PA T+ +P + +G L+RKH+WE N+KAS+R+WH++Y +++ M F+KD ++ Y +E+P L E V A DY K+ VF+++ +G EYLFQ V +
Sbjct: 25 DDEWDNENSSARLFERSRIKALAGSAMLIDEREAVQKKTFTKWVNSHLARVSCRITDLYADLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLIGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVLAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLKARRLRLEMNLGLQKVFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQADRVRAVNASAQRFATGGE-----GYKPCDPQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEQILSSDDYGKDLTSVVRLYCKHKAFEDEMSGRSGHLLQTIKEGEEMIAEDHFGSEKIRERIKDIQEQWANLEHLSAIRKKRLEDTTSSYQFQADADDVDAWMLDILRIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRSTIDALHEQA-AALPEERFNSTDVQNRLSGIEERYKELAELARLRKQALQDALTLYKMFSEADACELWIVEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLIHSGHPSEKEIKAQQDKLNTRWSQFRELVDKTKDALSSALSIQNYHLECNETKSWIREKTKVIESTQELGNDLAGVMALQRKLTGMERDLAAIEAKLTDLQKEAEKLEAEHPDQAQAIMDRLAEINNVWEEMKTTLKNREESLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLAEAEKLLTQHENIKNEINNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQSLLSQSHAYQLFLRDTKQAEAFLNNQE-YVLAHTE-LPNNLEAAEA-------AIKTQEDFMTTMDASEEKINAVVDTGRRLVNDENINSDKIEEKVDSIDSRHKKNRAGANDLLMRLKDNREMQKFLQDCQELSLWINEKMLTARDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGNQLIAEKPETEAIVKEKMSALHAMWEELESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQMLENQMDVRKKEVEELRSQAQALSQEGKSTDEVDGQRQV---VEVRFIELLAPLNERKKYLLASKEI--HQFNRDVEDEILWVEERMPLATSTDHGHNLQTV------QLLMKKNQTLQKEIQGHQHRNDDIFERSKMILDDSSLNAEAITQRLADLQALWSLLIEETEKRHRRLEESHRAQQYYFDGAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVAEGHPESERISMRQSQVDKLYAGLKDLSEERRGKLD------ERQRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGHIGQERVDSVNHMADDLINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASFELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRESEVLEAWKALLDACDGRRLRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLFGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTV------LTLCFSFLSTNSTRCSFTADDPETAVM--MAENADTNE--------------------LVNGSTEQRSSSKESS-------------PIP-----SPTADRKSKSGMQPQ----------------TAATLPAKTQEMPSAQ--FEGFLHRKHEWEGHNKKASSRSWHNVYCVINNQEMGFYKDSKNAASGIA--YHNEIPANLKEAVCEVATDYKKKKHVFKLKLNDGNEYLFQAKDDVSI 2267
BLAST of Spectrin beta chain vs. Ensembl Xenopus
Match: SPTBN1 (spectrin beta, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11275]) HSP 1 Score: 1336.24 bits (3457), Expect = 0.000e+0 Identity = 834/2384 (34.98%), Postives = 1356/2384 (56.88%), Query Frame = 1
Query: 211 SRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQN--PDKASKYEQLETQVKVTMDGLSVPL--ESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEIS----LFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFE-----------QLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQ------TFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPS-TTQSHPNLS--SSLPP 7251
R K L DERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE ++ + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R+ + + A R+ + + +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RL KHK FE E+S + L + EG+ ++ G E I + DIQ W L + RK +L + YQ+ +D DD + W+ + R+ +G T+ L++K++ E + NYR I+ + QA + L + V +L IE++Y++L ++A ++ L DALT+Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ +G+P+ + I QD LN W++ ++VD +D L S N+ ++C +T WIREK K+IES ELG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L ++ WE ++ +++R+ +L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + +F D +Q E LN QE Y++ + L NN +++ + E F+ M + E+ + V+ G+ L+ + N+ D+++ K ++D R KKN A + +LK+ + + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q A+ P + + + + L++ W EL + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK +++ +KK +E L+ ++ L Q+ D+ Q+ V+V L PL K +A+++I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ + D + + ++ ++D++ L + + L+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ LF + + ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N D+LI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A+++L + R+L ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW+ QE YL++ +G ++DE L+K+ F+K+ +E+F +++RL E R +K T E+ ++E+ T E + I Q++ R + D+ +E+ + Q+ +S++S P P SP K QP +A+ PA T+ +P + +G L+RKH+WE N+KAS+R+WH++Y +++ M F+KD ++ Y +E+P L E V A DY K+ VF+++ +G EYLFQ +M W+ AI +A + T S +TQS P S +LP
Sbjct: 30 GRFKQLQDEREAVQKKTFTKWVNSHLARVSCRITDLYADLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLIGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVLAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLKARRLRLEMNLGLQKVFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQADRVRAVNASAQRFATGGE-----GYKPCDPQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEQILSSDDYGKDLTSVVRLYCKHKAFEDEMSGRSGHLLQTIKEGEEMIAEDHFGSEKIRERIKDIQEQWANLEHLSAIRKKRLEDTTSSYQFQADADDVDAWMLDILRIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRSTIDALHEQA-AALPEERFNSTDVQNRLSGIEERYKELAELARLRKQALQDALTLYKMFSEADACELWIVEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLIHSGHPSEKEIKAQQDKLNTRWSQFRELVDKTKDALSSALSIQNYHLECNETKSWIREKTKVIESTQELGNDLAGVMALQRKLTGMERDLAAIEAKLTDLQKEAEKLEAEHPDQAQAIMDRLAEINNVWEEMKTTLKNREESLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLAEAEKLLTQHENIKNEINNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQSLLSQSHAYQLFLRDTKQAEAFLNNQE-YVLAHTE-LPNNLEAAEA-------AIKTQEDFMTTMDASEEKINAVVDTGRRLVNDENINSDKIEEKVDSIDSRHKKNRAGANDLLMRLKDNREMQKFLQDCQELSLWINEKMLTARDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGNQLIAEKPETEAIVKEKMSALHAMWEELESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQMLENQMDVRKKEVEELRSQAQALSQEGKSTDEVDGQRQV---VEVRFIELLAPLNERKKYLLASKEI--HQFNRDVEDEILWVEERMPLATSTDHGHNLQTVQLLMK------KNQTLQKEIQGHQHRNDDIFERSKMILDDSSLNAEAITQRLADLQALWSLLIEETEKRHRRLEESHRAQQYYFDGAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVAEGHPESERISMRQSQVDKLYAGLKDLSEERRGKLDERQRLFQLNREV----DDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGHIGQERVDSVNHMADDLINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASFELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRESEVLEAWKALLDACDGRRLRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLFGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRLQEEEERKRKPPTP--------------------ELSPKLSEDGSPQQWDGTKEGEQISQNGLPSDQESPRMAENADT-----NELVNGSTEQRSSSKES--SPIP-----SPTADRKSKSGMQPQ----------------TAATLPAKTQEMPSAQ--FEGFLHRKHEWEGHNKKASSRSWHNVYCVINNQEMGFYKDSKNAASGIA--YHNEIPANLKEAVCEVATDYKKKKHVFKLKLNDGNEYLFQAKDDEEMNTWIQAITNA------ITSDKTEVSLSTQSTPASSRAQTLPA 2317
BLAST of Spectrin beta chain vs. Ensembl Mouse
Match: Sptbn1 (spectrin beta, non-erythrocytic 1 [Source:MGI Symbol;Acc:MGI:98388]) HSP 1 Score: 1345.1 bits (3480), Expect = 0.000e+0 Identity = 842/2391 (35.22%), Postives = 1367/2391 (57.17%), Query Frame = 1
Query: 160 DEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDI-------RSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDK---ASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMI-DENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLS--SSLP 7248
D D+ N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R +N +K ++ Y + CD +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RLL KH+ FE E+S + E + EG+ ++ G E I + I+ W L + RK +L E +Q+ +D DD + W+ + ++ +G T+ L++K++ E + NYR I+ + QA S L + + V +L IE++ +++ ++ ++ L D L +Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ NG+P+ + I QD LN W++ ++VD K+D LLS N+ ++C +T WIREK K+IES +LG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L + WE ++ +++R+++L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + F D +Q E LN QE L + L + + E F+ M ++E+ + V++ G+ L+ + N+ DR+Q K ++D+R +KN AA +LK+ L + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q ++ P + + + L L+ W L + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK ++E +KK +E L+ ++ L Q+ SK ++T+ ++ LS E K ++ K I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ ++D + + +Q +I D + L + + LK+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ + + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N DELI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A++SL E R++ ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW++ QE YL++ +G ++DE L+K+ F+K+ +E+F L+RLTT+E+ + + + + + +V E + ++ T + + Q + R ++++S E+ + Q+ +S++S P P + + +S P S + P L PA M+G L RKH+WE N+KAS+R+WH++Y +++ M F+KD + Y E+P+ L E + A DY K+ VF++R +G EYLFQ +M W+ AI+SA + + ++TQS P S +LP
Sbjct: 26 DVDDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQAERVRGVNASAQKFATDGEGY-KPCD-----------PQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHKDVAEEITNYRPTIDTLHEQA-SALPQAHAESPDVKGRLAGIEERCKEMAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHNGHPSEKEIRAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLA---------HTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNREAASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQALSQEGKSTDEVDSKRLTVQTKFMELLEPLS---ERKHNLLASKEI-HQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIK------KNQTLQKEIQGHQPRIDDIFERSQNIITDSSSLNAEAIRQRLADLKQLWGLLIEETEKRHRRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLD------ERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVNNMADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKSLLDACEGRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPDPNT--KVSE--EAESQQWDTSKGDQVSQNGLPAEQGSPRMAGTMETS-----EMVNGAAEQRTSSKESSPVPSP------TLDRKAKSALPAQSAATLPARTLET----------PAAQ---------MEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKSAASGIP--YHSEVPVSLKEAICEVALDYKKKKHVFKLRLSDGNEYLFQAKDDEEMNTWIQAISSAIS-----SDKHDTSASTQSTPASSRAQTLP 2329
BLAST of Spectrin beta chain vs. Ensembl Mouse
Match: Sptbn1 (spectrin beta, non-erythrocytic 1 [Source:MGI Symbol;Acc:MGI:98388]) HSP 1 Score: 1345.1 bits (3480), Expect = 0.000e+0 Identity = 842/2391 (35.22%), Postives = 1367/2391 (57.17%), Query Frame = 1
Query: 160 DEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDI-------RSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDK---ASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMI-DENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLS--SSLP 7248
D D+ N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R +N +K ++ Y + CD +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RLL KH+ FE E+S + E + EG+ ++ G E I + I+ W L + RK +L E +Q+ +D DD + W+ + ++ +G T+ L++K++ E + NYR I+ + QA S L + + V +L IE++ +++ ++ ++ L D L +Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ NG+P+ + I QD LN W++ ++VD K+D LLS N+ ++C +T WIREK K+IES +LG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L + WE ++ +++R+++L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + F D +Q E LN QE L + L + + E F+ M ++E+ + V++ G+ L+ + N+ DR+Q K ++D+R +KN AA +LK+ L + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q ++ P + + + L L+ W L + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK ++E +KK +E L+ ++ L Q+ SK ++T+ ++ LS E K ++ K I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ ++D + + +Q +I D + L + + LK+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ + + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N DELI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A++SL E R++ ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW++ QE YL++ +G ++DE L+K+ F+K+ +E+F L+RLTT+E+ + + + + + +V E + ++ T + + Q + R ++++S E+ + Q+ +S++S P P + + +S P S + P L PA M+G L RKH+WE N+KAS+R+WH++Y +++ M F+KD + Y E+P+ L E + A DY K+ VF++R +G EYLFQ +M W+ AI+SA + + ++TQS P S +LP
Sbjct: 26 DVDDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQAERVRGVNASAQKFATDGEGY-KPCD-----------PQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHKDVAEEITNYRPTIDTLHEQA-SALPQAHAESPDVKGRLAGIEERCKEMAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHNGHPSEKEIRAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLA---------HTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNREAASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQALSQEGKSTDEVDSKRLTVQTKFMELLEPLS---ERKHNLLASKEI-HQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIK------KNQTLQKEIQGHQPRIDDIFERSQNIITDSSSLNAEAIRQRLADLKQLWGLLIEETEKRHRRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLD------ERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVNNMADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKSLLDACEGRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPDPNT--KVSE--EAESQQWDTSKGDQVSQNGLPAEQGSPRMAGTMETS-----EMVNGAAEQRTSSKESSPVPSP------TLDRKAKSALPAQSAATLPARTLET----------PAAQ---------MEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKSAASGIP--YHSEVPVSLKEAICEVALDYKKKKHVFKLRLSDGNEYLFQAKDDEEMNTWIQAISSAIS-----SDKHDTSASTQSTPASSRAQTLP 2329
BLAST of Spectrin beta chain vs. Ensembl Mouse
Match: Sptbn1 (spectrin beta, non-erythrocytic 1 [Source:MGI Symbol;Acc:MGI:98388]) HSP 1 Score: 1276.15 bits (3301), Expect = 0.000e+0 Identity = 766/2094 (36.58%), Postives = 1235/2094 (58.98%), Query Frame = 1
Query: 160 DEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDI-------RSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDK---ASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMI-DENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKF 6363
D D+ N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R +N +K ++ Y + CD +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RLL KH+ FE E+S + E + EG+ ++ G E I + I+ W L + RK +L E +Q+ +D DD + W+ + ++ +G T+ L++K++ E + NYR I+ + QA S L + + V +L IE++ +++ ++ ++ L D L +Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ NG+P+ + I QD LN W++ ++VD K+D LLS N+ ++C +T WIREK K+IES +LG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L + WE ++ +++R+++L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + F D +Q E LN QE L + L + + E F+ M ++E+ + V++ G+ L+ + N+ DR+Q K ++D+R +KN AA +LK+ L + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q ++ P + + + L L+ W L + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK ++E +KK +E L+ ++ L Q+ SK ++T+ ++ LS E K ++ K I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ ++D + + +Q +I D + L + + LK+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ + + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N DELI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A++SL E R++ ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW++ QE YL++ +G ++DE L+K+ F+K+ +E+F
Sbjct: 26 DVDDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQAERVRGVNASAQKFATDGEGY-KPCD-----------PQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHKDVAEEITNYRPTIDTLHEQA-SALPQAHAESPDVKGRLAGIEERCKEMAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHNGHPSEKEIRAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLA---------HTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNREAASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQALSQEGKSTDEVDSKRLTVQTKFMELLEPLS---ERKHNLLASKEI-HQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIK------KNQTLQKEIQGHQPRIDDIFERSQNIITDSSSLNAEAIRQRLADLKQLWGLLIEETEKRHRRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLD------ERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVNNMADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKSLLDACEGRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERF 2073
BLAST of Spectrin beta chain vs. Ensembl Mouse
Match: Sptbn1 (spectrin beta, non-erythrocytic 1 [Source:MGI Symbol;Acc:MGI:98388]) HSP 1 Score: 1259.2 bits (3257), Expect = 0.000e+0 Identity = 756/2077 (36.40%), Postives = 1220/2077 (58.74%), Query Frame = 1
Query: 211 SRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDI-------RSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDK---ASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMI-DENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKF 6363
R K L DERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R +N +K ++ Y + CD +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RLL KH+ FE E+S + E + EG+ ++ G E I + I+ W L + RK +L E +Q+ +D DD + W+ + ++ +G T+ L++K++ E + NYR I+ + QA S L + + V +L IE++ +++ ++ ++ L D L +Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ NG+P+ + I QD LN W++ ++VD K+D LLS N+ ++C +T WIREK K+IES +LG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L + WE ++ +++R+++L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + F D +Q E LN QE L + L + + E F+ M ++E+ + V++ G+ L+ + N+ DR+Q K ++D+R +KN AA +LK+ L + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q ++ P + + + L L+ W L + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK ++E +KK +E L+ ++ L Q+ SK ++T+ ++ LS E K ++ K I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ ++D + + +Q +I D + L + + LK+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ + + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N DELI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A++SL E R++ ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW++ QE YL++ +G ++DE L+K+ F+K+ +E+F
Sbjct: 30 GRFKQLQDEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQAERVRGVNASAQKFATDGEGY-KPCD-----------PQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHKDVAEEITNYRPTIDTLHEQA-SALPQAHAESPDVKGRLAGIEERCKEMAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHNGHPSEKEIRAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLA---------HTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNREAASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQALSQEGKSTDEVDSKRLTVQTKFMELLEPLS---ERKHNLLASKEI-HQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIK------KNQTLQKEIQGHQPRIDDIFERSQNIITDSSSLNAEAIRQRLADLKQLWGLLIEETEKRHRRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLD------ERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVNNMADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKSLLDACEGRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERF 2060
BLAST of Spectrin beta chain vs. Ensembl Mouse
Match: Sptbn2 (spectrin beta, non-erythrocytic 2 [Source:MGI Symbol;Acc:MGI:1313261]) HSP 1 Score: 1244.18 bits (3218), Expect = 0.000e+0 Identity = 785/2397 (32.75%), Postives = 1293/2397 (53.94%), Query Frame = 1
Query: 193 SKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCD--QDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKK--LDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLN-------------TDRQFINE---ALIN---IEQTAEHEVHEIIQPITEN-------VQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDM--LSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSS--LPPQAQ 7260
+++FERSRIKALADERE VQKKTFTKW+NS L VT ++ DLY DLRDG+ LL LLE+LS E +PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RLTLGL+WTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VN+ NFT SWR GL F A++HKHRPDL+DF S + + NL AF++AE LG+ LLDPEDVNV PDE+S+ITYVA+YYHYF+ +KA +V KR+ K+L+ +E E +++ Y+SL S+LL+WI TI LN RQ +NS+ G+Q Q+ +FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KAA+RE+W+++N L+ + + G L V AA++KHEAIETDI AY + + ++ L E Y+DI I +N V LW L Q + RRE L L++ + + + + + + + + GKHL VE+LL+ HEL+E+DI +R+ + + A R FCD +++R + ++ E+ + + + L + R+ L+ S +W+F+ + E W++E ++ + D G DL+ V RLL KH E+S + L+ L +G+ LV G + + ++Q WE L E R +L + YQ+ +D +D E W+ + RL +G T+ L R+++ E + +R ++ +R QA + L ++ V ++ +E+ Y++L A + L AL Y +L+++ + W+ EK+++L + +E+LEV++ RFE E E+ A +V VN+++E L+ P I+ Q+ LN W + + D K+ L S N+ ++C +T W+REK K+IES LG DL V+ QR++ +RD+ AI A++ L + + + + A I +L V WE L+ +R R+ +L + F++ LDDF WLG+ QT +AS+ P + EAE L+ ++ + R E+ + + +G++ + + D Q + L+ R+E++ W+ L + E ++ RL + F DARQ E +L++QE L + L + + + + E F+ M ++ + + +L+ G+ L+ + N++ +++Q K ++++R +KN A Q +L++ LQD +L + EK+ ++S ++ + + +A E+ A + +++++K G++ + + P K + + L++L+ W EL + K ++L NR +LF +S ++ WL++++ Q+ +DD +TS+ LKK + M + K+ + + + Q+ A + E+ V+ L P++ + + QF +D +DEI W+ E++ + + +E L Q L ++++++ EI+ ++ L +E QR L A + +L++ + L+ E+E L L Q+F D +E +W+ E+EL +MG +KD+ + ++K Q LE + +Y I++ S + P+ + ++ V+ + SLK + E++ + + C ++E WI ER +A S + G+D + T+LRD+F FS +T+ IG +V+ AN + LI G H +++ WKD +NE WADLLEL+DTR Q+L +A++L R+ ++ L +Q K+ ++ + G+D + LQR+ +E D+ L + + L Y DK + + Q + +A+ L+ R+ L+ D F VREL+ W++ + +QM+ + +PRDVS +L++ N + +K E++++ + FS C+++G+ LL H + EI K ++ +R KW +D L L++EV + RDA AEAW+ SQE + + LG T+DE +L+K+ FQK+ + EE+F L++LT +E R + T ++ +L++ + TA + P T+ T +P++ QQ + + N E +G + + + + P+ A SP+PQ S S+ H ++ T LSA + M+G L RK + E N+KA+NR+W ++Y +L + + F+KD R Y E+P+ L + A DY KR VF++ ++G EYLFQ +M+ W+ +N+A + P + L+ + +PP +Q
Sbjct: 40 ARLFERSRIKALADEREAVQKKTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGETLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAEHLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQEKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVAAELAAEHYHDIKRIAARQNNVARLWDFLRQMVAARRERLLLNLELQKVFQDLLYLMDWMAEMKGRLQSQDLGKHLAGVEDLLQLHELVEADIAVQAERVRAVSASALR---FCDPGKEYRPC----DPQLVSERVATLEQSYEALCELAATRRARLEESRRLWRFLWEVGEAEAWVREQQHLLASADTGRDLTGVLRLLNKHAALRGEMSGRLGPLKLTLEQGQQLVAEGHPGANQASTRAAELQAQWERLEALAEERAQQLAQAASLYQFQADANDMEAWLVDALRLVSSPEVGHDEFSTQALARQHRALEEEIRAHRPTLDALREQA-AALPPALSHTPEVQGRVPTLEQHYEELQARAGERARALEAALAFYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNALAARVTAVNDIAEQLLKASPPGKDRIIGTQEQLNQRWQQFRSLADGKKAALTSALSIQNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAISARVGELTQEANALAAGHPAQAPAINTRLGEVQAGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRTLGEEVTRDQADP-QCLFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVL---------SHTEMPGTLQAADAAIKKLEDFMSTMDANGERIRGLLEAGRQLVSKGNIHAEKIQEKADSIEKRHRKNQEAVQQLLGRLRDNREQQHFLQDCQELRLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMAELAANKDWLDKVDKEGRELTLEKPELKVVVSEKLEDLHRRWDELETTTQAKARSLFDANRAELFAQSCSALESWLESLQAQLHSDD----YGKDLTSVNILLKKQQMLEREMAVREKEVEAIQAQAQALAQEDQS---AGEVERTSRAVEEKFRALCQPMKERCRRLHASREQHQFHRDVEDEILWVTERLPM----ASSLEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADL-KERQRT-----LGTAAAGPELAELQEMWKRLSHELELRGKRLEEALRAQQFYRDAAEAEAWMGEQELHMMGQE-KAKDELSAQAEVKKHQVLEQALADYAQTIKQLAASSQDMIDHEHPESTRLTIRQAQVDKLYASLKELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSKDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALARVQHKQ--QQLPDGTGRDLNAAEALQRRHCAYEHDIQALSTQVQQVQDDGQRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMDGINLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGQELLARSHYAAEEISEKLSQLQSRRQETADKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQKSAVAWEERFSALEKLTALEERENERKRKREEEERRKQPPTSEPMASQPEGSLVDGQRVPDTAWDGTQSKLPPSTQAPSVNGVCTDTDSSQPLLE------QQRLEQSNV--------PEGPGSGTGDESSGPRGERQTLPRGPAPSPMPQ---------SRSSEAAHGATLPTRGPELSAQEQ-------------MEGMLCRKQEMEAFNKKAANRSWQNVYCVLRRGSLGFYKDARAASAGVP--YHGEVPVSLARAQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSAPGESEEPVVPSASRGLTRAMTMPPVSQ 2360
BLAST of Spectrin beta chain vs. UniProt/SwissProt
Match: sp|Q01082|SPTB2_HUMAN (Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2) HSP 1 Score: 1352.42 bits (3499), Expect = 0.000e+0 Identity = 842/2393 (35.19%), Postives = 1368/2393 (57.17%), Query Frame = 1
Query: 160 DEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDI-------RSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKAS-KYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMI-DENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFIN------EALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSA-SRPMRQVNPSNTNPSTTQSHPNLSSSL 7245
D D+ N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R +N +K ++ Y + CD +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RLL KH+ FE E+S + E + EG+ ++ G E I + I+ W L + RK +L E +Q+ +D DD + W+ + ++ +G T+ L++K++ E + NYR ++ + QA S L + V +L IE++Y+++ ++ ++ L D L +Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ +G+P+ + I QD LN W++ ++VD K+D LLS N+ ++C +T WIREK K+IES +LG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L + WE ++ +++R+++L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + F D +Q E LN QE L + L + + E F+ M ++E+ + V++ G+ L+ + N+ DR+Q K ++D+R +KN A +LK+ L + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q ++ P + + + L L+ W L + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK ++E +KK +E L+ ++ L Q+ ++L Q K M+ L E K ++ K I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ ++D + + +Q ++ D + L + + LK+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ + + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N DELI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A++SL E R++ ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW++ QE YL++ +G ++DE L+K+ F+K+ +E+F L+RLTT+E+ + + + E + + AE + + T + + + Q + R ++D+ SE+ + Q+ +S++S P P S +++K P+ SA+ PA T+ P + M+G L RKH+WE N+KAS+R+WH++Y +++ M F+KD + Y E+P+ L E V A DY K+ VF++R +G EYLFQ +M W+ AI+SA S +V+ S + + L +S+
Sbjct: 26 DVDDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLVLSQDYGKHLLGVEDLLQKHTLVEADIGIQAERVRGVNASAQKFATDGEGY-KPCD-----------PQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRPTLDTLHEQA-SALPQEHAESPDVRGRLSGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSEKEIKAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLA---------HTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNRETASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQALSQEGKSTDEVDSKRLTVQTKF-MELLEPLNERKHNLLASKEI-HQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIK------KNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGLLIEETEKRHRRLEEAHRAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLD------ERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVNHLADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKSLLDACESRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPEPSTKVSEEAESQ---------QQWDTSKGEQVSQNGLPAEQGSPRMAETVDT-----SEMVNGATEQRTSSKESSPIPSPTSD--------RKAKTALPAQ---------------SAATLPARTQETPSAQ--MEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKTAASGIP--YHSEVPVSLKEAVCEVALDYKKKKHVFKLRLNDGNEYLFQAKDDEEMNTWIQAISSAISSDKHEVSASTQSTPASSRAQTLPTSV 2333
BLAST of Spectrin beta chain vs. UniProt/SwissProt
Match: sp|Q62261|SPTB2_MOUSE (Spectrin beta chain, non-erythrocytic 1 OS=Mus musculus OX=10090 GN=Sptbn1 PE=1 SV=2) HSP 1 Score: 1345.1 bits (3480), Expect = 0.000e+0 Identity = 842/2391 (35.22%), Postives = 1367/2391 (57.17%), Query Frame = 1
Query: 160 DEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDI-------RSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDK---ASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMI-DENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLS--SSLP 7248
D D+ N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +LP V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ V+ LW+ LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R +N +K ++ Y + CD +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL+SV RLL KH+ FE E+S + E + EG+ ++ G E I + I+ W L + RK +L E +Q+ +D DD + W+ + ++ +G T+ L++K++ E + NYR I+ + QA S L + + V +L IE++ +++ ++ ++ L D L +Y++ +++D+ WI EK+++L N + +E+LEV++HRFE E E+ +A +V VN ++ L+ NG+P+ + I QD LN W++ ++VD K+D LLS N+ ++C +T WIREK K+IES +LG DL VM QR++ M+RD+ AIEAK+ L + +++ + A+ I +L + WE ++ +++R+++L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + F D +Q E LN QE L + L + + E F+ M ++E+ + V++ G+ L+ + N+ DR+Q K ++D+R +KN AA +LK+ L + LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G Q ++ P + + + L L+ W L + K Q L N+ +LF +S + KWL +E QI +DD +TS+ LKK ++E +KK +E L+ ++ L Q+ SK ++T+ ++ LS E K ++ K I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ ++D + + +Q +I D + L + + LK+ L EE EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ + + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N DELI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ + IQ+K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A++SL E R++ ++ D F SMVR+L+ W+E+V Q+E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++T+KR + KW + + L L++EV+Q++RDA+ AEAW++ QE YL++ +G ++DE L+K+ F+K+ +E+F L+RLTT+E+ + + + + + +V E + ++ T + + Q + R ++++S E+ + Q+ +S++S P P + + +S P S + P L PA M+G L RKH+WE N+KAS+R+WH++Y +++ M F+KD + Y E+P+ L E + A DY K+ VF++R +G EYLFQ +M W+ AI+SA + + ++TQS P S +LP
Sbjct: 26 DVDDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQAERVRGVNASAQKFATDGEGY-KPCD-----------PQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHKDVAEEITNYRPTIDTLHEQA-SALPQAHAESPDVKGRLAGIEERCKEMAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHNGHPSEKEIRAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLA---------HTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNREAASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYG----KDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQALSQEGKSTDEVDSKRLTVQTKFMELLEPLS---ERKHNLLASKEI-HQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIK------KNQTLQKEIQGHQPRIDDIFERSQNIITDSSSLNAEAIRQRLADLKQLWGLLIEETEKRHRRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLD------ERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVNNMADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQDKHKKLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKSLLDACEGRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPDPNT--KVSE--EAESQQWDTSKGDQVSQNGLPAEQGSPRMAGTMETS-----EMVNGAAEQRTSSKESSPVPSP------TLDRKAKSALPAQSAATLPARTLET----------PAAQ---------MEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKSAASGIP--YHSEVPVSLKEAICEVALDYKKKKHVFKLRLSDGNEYLFQAKDDEEMNTWIQAISSAIS-----SDKHDTSASTQSTPASSRAQTLP 2329
BLAST of Spectrin beta chain vs. UniProt/SwissProt
Match: sp|Q00963|SPTCB_DROME (Spectrin beta chain OS=Drosophila melanogaster OX=7227 GN=beta-Spec PE=1 SV=2) HSP 1 Score: 1299.26 bits (3361), Expect = 0.000e+0 Identity = 780/2103 (37.09%), Postives = 1245/2103 (59.20%), Query Frame = 1
Query: 148 NALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLK--SEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQL---ETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKI-------EEFKKSCVSLPDEYKGIVKDVEDNFNSLKIICAEKKTEIS----LFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKK 6408
N DE E N +S++FERSRIKALA+ERE+VQKKTFTKW+NS L V +I DLYVD+RDGK L+ LLE+LS E +PKPT+G+MRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN L LGLIWTIILRFQ+QDI +E + KSAKDALLLWCQMKTAGY +VN+RNFT SWR GL F A+IHKHRPDL+ F ++ + I+NL+ AFD+AE+ LG+ LLD EDV V PDE+S+ITYV +YYHYF+ LK +V KR+ K++ +E+++M+ Y++ S LL+WI TI+ L R+F NS+ G+Q Q+ F+ YRT EKP KFVEK +LEVLLFT++S + K Y P E +S IN AW+ L AE+ RE ALR+EL+RQEKL LA +F++KA++RE+W+++N L+ + + G +L V AA KKHEAIETDI+AYEE + + + D LE E Y+D+ I+ K+ V+ LW LL+ L RR L+ LQ+ E + + I D+YGKHLM VE+LL+ H L+E+DI + +R++ ++ + +++ D + + +I + + EL+ +R+ L+ S +WQF D + EE WIKE I++ ++G+DL++V+ +L KHK E E++S L+N G L+ G + I + +I N W+ L+D T+ R+ +L ++Y+Q +D DD + W+ + R+ + +G + + L++K++ + ++NY + I+ + QA+S L + + V K+L+ I+ +Y++L ++A +++LLDAL++Y+L++++D V WI EK K L P DIE++E++KHRFE F+ E+ A +V VN L+ L+ +PN I+ Q++LN W+ + + ++K D+L S + F+++C++TI WI +K +++ D L DL VM QRR++ M RD+ AI+AK+ L + + I + AK I ++ + WE L Q++++RDS L D+HRF++ LD F WL + QT++AS++ P S EAEKL+N++ S R+E+ + + M+ G+ S D Q++ L+ R+ ++ W+ L+ + E ++ L + L +F DARQ E +L+ QE +L KD + NL + +E F+ M +++ + +L+ TL+ +++ D++ + +N+ R N A ++ KLK QV LHE LQD+++L + + EK + S + K+ S + +A E EI A + + E K ++ S + P FK I L L + +L +EK L NRE L +++ + ++ ++E QIV+ D + + +TS+ ++K ++ K + +E + +E L++ P++ K E + +T V + + PL + +K A QF +D +DE W++EK+ + + + +L L+ +++S+ EI N +++++ +++IDE H ++ L + + L + +E + L VQ++ D E SW+SE+EL +M + KD+ + +++K +NLE +++Y I +F +S D ++ + LK + E++ ++ LF++ + ++E WI +R +A S + G+D D TLL +RF F+ +T +G +V + N D LIQ H + +I+ WKD +NE W DLLELI+TR Q+L ++ +LH+++ D + +L I EK+ V ++LG+D SVS LQRK NF +DL+ L S + S L Y DK + + QE++ A+ +L+ + + RK + D F +MVR L+ W+E++ QM KPRDVSG+ELL+ NH+SLK E+D++E+NF C++LG+ LL H S +IK + +++ R+ L ++W ++L L++EVYQ+ARDAA AEAW+I+QE YL + LG T+DE L+KK F+K+ QEE+F L+RLTT E++ K
Sbjct: 18 NEYIDEYEYDGGNSSSRLFERSRIKALAEERESVQKKTFTKWVNSHLCRVNCRIADLYVDMRDGKHLIKLLEVLSGERLPKPTKGKMRIHCLENVDKALQFLREQRVHLENIGSHDIVDGNASLNLGLIWTIILRFQIQDITIEEVDNKETKSAKDALLLWCQMKTAGYHNVNVRNFTTSWRDGLAFNAIIHKHRPDLVQFEKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDVFVEHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMENDKMVHDYENFTSDLLKWIETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQSKMRANNQKPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFL----SDDPESYKPCDPEIIVSRVQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDALHKQAES-LKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKD---------DTPVNLEQAENQLKRHEAFLTTMEANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRALDQHEKLKNQVKLHEFLQDLEELAEWVQEKYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKERLFEAEKSAQELSKEKPEFKDVIEPKLKELAKQFDDLEVHTKEKGAMLFDANREVLVQQTCDDIDSYITDLEKQIVSGD----TANDLTSVNILMQKQQVIQTQMAVKARQVEEIDKQTEYLQKTVPEE--KIEPIVVKKTAVLERFEKIKAPLLERQKALEKKKEAFQFCRDVEDEKLWIDEKLPV----ANSPDYGNSLFNVHVLKKKNQSLATEIDNHEPRINAICNNGRKLIDEGHEDAKKFEALISDLTQKWQELKDAIENRRKHLLESEKVQQYFFDAQEAESWMSEQELYMM-VEDRGKDEISAQNLMKKHENLEQSVEDYANTIRQLGEVARQFSGDDISSGDAVAVKQSQLDKLYAGLKDLAGERRARLNEALQLFMLSREV----DDLEQWITDREVVAGSQELGQDFDHVTLLSERFNEFARDTEAVGGERVAKVNGIADNLIQAGHSDSATIAEWKDNLNESWQDLLELIETRTQMLAASRELHKFFHDCKDVLGRILEKQHG--VSDELGRDAGSVSTLQRKHYNFLQDLITLYSQVQQIQEESAKLQDAYAGDKAKEITNREQEVLHAWDNLQAMCDARKQKLADTGDLFRFFNMVRILMIWMEDLVRQMNTSEKPRDVSGVELLMNNHQSLKAEIDTREDNFGACISLGKELLTRNHYASADIKDRLMTLSNSRNALLRRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLLSSELGHTIDEVENLIKKHEAFEKSAAAQEERFSALERLTTFELKEMK 2089 HSP 2 Score: 131.724 bits (330), Expect = 6.681e-29 Identity = 140/618 (22.65%), Postives = 280/618 (45.31%), Query Frame = 1
Query: 4612 QFLQDCDDEIDWMNEKIDLIRNR--SKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVIN---SKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLP---DEYKGIVKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ---NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELID-AFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRS-PE---IKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNT 6417
QF D DE +W+ EK ++ + T+ +L +HK++++EI + ++ ++ + +I E H + D + ++ ++L + + + L N + + D +V +W+ LD + +V + +D+ ++ +++K +++ E+KNY I+ K SL E + K +E N K + K + Y+L +E WI E+TK+ + GKD++ +++ RF F E N +S+V N+ +L+ +HP + I ++ +N+ W+ L E + ++ LKSA + +Y + + + I++KK + + L D V LQR+L ++DL + + +++ +N++ + + EA +I++R I+ + L ++L++R E D H FL + W+ + + P + E LL H+S++ E+D+ E++ + G L P+ ++ + + D + L Q W N LS ++ + RDA E + QE +L+ ++ + L++ LK+ F LTTME K+NT
Sbjct: 639 QFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLS------KHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWM----LDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDALHKQAESLKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMN-ANASRVAVVNQLARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPE--EAKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRHEAF----------------LTTMEANDDKINT 1227 HSP 3 Score: 89.7373 bits (221), Expect = 3.745e-16 Identity = 47/174 (27.01%), Postives = 85/174 (48.85%), Query Frame = 1
Query: 6784 LSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFSSIRLK 7305
+ AS + P +G + RKH+W++ +KASNR+W +Y+ R++F+KD++ +K P+ ++ E L A DY K+ V RV+ NGA +L Q +M++WV ++ + S +T + S +LP +Q + +R F +++ K
Sbjct: 2131 VGASHDDSERGGTPGAGEGHEGYVTRKHEWDSTTKKASNRSWDKVYMAAKAGRISFYKDQKGYKSNPELTFRGEPSYDLQNAAIEIASDYTKKKHVLRVKLANGALFLLQAHDDTEMSQWVTSLKAQS-------------DSTAVAASRSQTLPATSQKDEPKRRSFFTLKKK 2291
BLAST of Spectrin beta chain vs. UniProt/SwissProt
Match: sp|O15020|SPTN2_HUMAN (Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3) HSP 1 Score: 1252.65 bits (3240), Expect = 0.000e+0 Identity = 792/2375 (33.35%), Postives = 1295/2375 (54.53%), Query Frame = 1
Query: 193 SKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCD--QDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEAL--INIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKR---PQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAIN--------SASRPMRQVNPSNTNPSTTQSHPNLSSSLPP 7251
+++FERSRIKALADERE VQKKTFTKW+NS L VT ++ DLY DLRDG+ LL LLE+LS EI+PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RLTLGL+WTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VN+ NFT SWR GL F A++HKHRPDL+DF S + + NL AF++AE LG+ LLDPEDVNV PDE+S+ITYVA+YYHYF+ +KA +V KR+ K+L+ +E E++++ Y+SL S+LL+WI TI LN RQ +NS+ G+Q Q+ +FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KAA+RE+W+++N L+ + + G L V AA++KHEAIETDI AY + + ++ L E Y+DI I ++ V LW L Q + RRE L L++ + + + + + + + + G+HL VE+LL+ HEL+E+DI +R+ + + A R FC+ +++R + ++ E+ + + L + R+ L+ S +W+F+ + E W++E ++ + D G DL+ RLL KH E+S + L+ L +G+ LV G +A+ ++Q WE L E R +L + YQ+ +D +D E W+ + RL LG T+ L R+++ E + ++R ++ +R QA + L ++ V ++ +E+ Y++L A + L AL +Y +L+++ + W+ EK+++L + +E+LEV++ RFE E E+ A ++ VN+++E L+ P IVN Q+ LN+ W + + D K+ L S N+ ++C +T W+REK K+IES LG DL V+ QR++ +RD+ AI A++ L + + + + A I +L V WE L+ +R R+ +L + F++ LDDF WLG+ QT +AS+ P + EAE L+ ++ + R E+ + + +G++ + + D Q + L+ R+E++ W+ L + E ++ RL + F DARQ E +L++QE L + L + + + + E F+ M ++ + + +L+ G+ L+ E N++ D+++ K +++ R KKN AAQ +L++ LQD +L + EK+ ++S ++ + + +A E+ A + +++++K G++ + + P K + + L +L+ W EL + K ++L NR +LF +S ++ WL++++ Q+ +DD +TS+ LKK E+ ++K +E ++ ++ L Q++ A + E+ V+ L P+ + QF +D +DEI W+ E++ + + ME L Q L ++++++ EI+ ++ L +E QR L A + +L++ + L E+E L + L Q+F D +E +W+ E+EL +MG +KD+ + ++K Q LE + +Y I + S + P+ + ++ V+ + LK + E++ + + C ++E WI ER +A S + G+D + T+LRD+F FS +T+ IG +V+ AN + LI G H +++ WKD +NE WADLLEL+DTR Q+L +A++L R+ ++ L +Q K+ ++ + G+D + LQR+ +E D+ L + + L Y DK + + Q + +A+ L+ R+ L+ D F VREL+ W++EV +QM+ + +PRDVS +L++ N + +K E++++ + FS C+++G+ LL H + EI K ++ +R +KW +D L L++EV + RDA AEAW+ SQE + + LG T+DE +L+K+ FQK+ + EE+F L++LT +E R K+ R+ E TA +++ T + T++ P Q S++ + Q++ P P S + P+ ++ R P PS M + S ST+ A+ P P + M+G L RK + E +KA+NR+W ++Y +L + + F+KD + Y E+P+ L + A DY KR VF++ ++G EYLFQ +M+ W+ +N ++ P V PS T T + ++PP
Sbjct: 40 ARLFERSRIKALADEREAVQKKTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQEKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDLLYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALR---FCNPGKEYRPC----DPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQQHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASARAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEFSTQALARQHRALEEEIRSHRPTLDALREQA-AALPPTLSRTPEVQSRVPTLERHYEELQARAGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSIQNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTREANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADP-QCLFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVL---------SHTEMPGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRHKKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLFDANRAELFAQSCCALESWLESLQAQLHSDD----YGKDLTSVNILLKKQQMLEWEMAVREKEVEAIQAQAKALAQED-QGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDEILWVTERLPM----ASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADL-RERQRA-----LGAAAAGPELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQE-KAKDELSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLKELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALARVQHKQ--QQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQDDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYAAEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPAPEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQ-------APSVNGVCTDGEPSQPLLGQQRLEHSSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQ-----SRSTESAHAATLPPRG-PEPSAQEQMEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVP--YHGEVPVSLARAQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEPVVPSTTRGMTR------AMTMPP 2357
BLAST of Spectrin beta chain vs. UniProt/SwissProt
Match: sp|Q9QWN8|SPTN2_RAT (Spectrin beta chain, non-erythrocytic 2 OS=Rattus norvegicus OX=10116 GN=Sptbn2 PE=1 SV=2) HSP 1 Score: 1251.5 bits (3237), Expect = 0.000e+0 Identity = 783/2393 (32.72%), Postives = 1299/2393 (54.28%), Query Frame = 1
Query: 193 SKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCD--QDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLN-------------TDRQFINE---ALINIEQ---TAEHEVHEIIQPITEN-------VQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSS--LPPQAQ 7260
+++FERSRIKALADERE VQKKTFTKW+NS L VT ++ DLY DLRDG+ LL LLE+LS E +PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RLTLGL+WTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VN+ NFT SWR GL F A++HKHRPDL+DF S + + NL AF++AE LG+ LLDPEDVNV PDE+S+ITYVA+YYHYF+ +KA +V KR+ K+L+ +E E +++ Y+SL S+LL+WI TI LN RQ +NS+ G+Q Q+ +FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KAA+RE+W+++N L+ + + G L V AA++KHEAIETDI AY + + ++ L E Y+DI I +N V LW L + + RRE L L++ + + + + + + + + GKHL VE+LL+ HEL+E+DI +R+ + + A R FCD +++R + ++ E+ + + + L + R+ L+ S +W+F+ + E W++E ++ + + G DL+ V RLL KH E+S + L+ L +G+ LV G + + ++Q WE L E R +L + YQ+ +D +D E W+ + RL +G T+ L R+++ E + +R ++ +R QA + L ++ V ++ +E+ Y++L A + L AL Y +L+++ + W+ EK+++L + +E+LEV++ RFE E E+ A +V V++++E L+ P I+ Q+ LN W + + D K+ L S N+ ++C +T W+REK K+IES +LG DL V+ QR++ +RD+ AI A++ L + + + + A I +L V WE L+ +R R+ +L + F++ LDDF WLG+ QT +AS+ P + EAE L+ ++ + R E+ + + +G++ + + D Q + L+ R+E++ W+ L + E ++ RL + F DARQ E +L++QE +L + L + + + + E F+ M ++ + + +L+ G+ L+ + N++ +++Q K ++++R +KN A Q +L++ LQD +L + EK+ ++S ++ + + +A E+ A + +++++K G++ + + P K + + L++L+ W EL + K ++L NR +LF +S ++ WL++++ Q+ +DD +TS+ LKK E+ ++K +E ++ ++ L Q++ A + E+ V+ L P++ + QF +D +DEI W+ E++ + + +E L Q L ++++++ EI+ ++ L +E QR L A + +L++ + L+ E+E L L Q+F D +E +W+ E+EL +MG +KD+ + ++K Q LE + +Y I++ S + P+ + ++ V+ + LK + E++ + + C ++E WI ER +A S + G+D + T+LRD+F FS +T+ IG +V+ AN + LI G H +++ WKD +NE WADLLEL+DTR Q+L +A++L R+ ++ L +Q K+ ++ + G+D + LQR+ +E D+ L + + L Y DK + + Q + +A+ L+ R+ L+ D F VREL+ W++ + +QM+ + +PRDVS +L++ N + +K E++++ + FS C+++G+ LL H + EI K ++ +R +KW +D L L++EV + RDA AEAW+ SQE + + LG T+DE +L+K+ FQK+ + EE+F L++LT +E R + T ++ +L++ ++ TA + P T+ T +P++ QQ + + N E +G + + + + P+ A SP+PQ + S+ S V L LSA + M+G L RK + E N+KA+NR+W ++Y +L + + F+KD R Y E+P+ L + A DY KR VF++ ++G EYLFQ +M+ W+ +N+A + P + L+ + +PP +Q
Sbjct: 40 ARLFERSRIKALADEREAVQKKTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGETLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAEHLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQEKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVAAELAAEHYHDIKRIAARQNNVARLWDFLREMVAARRERLLLNLELQKVFQDLLYLMDWMAEMKGRLQSQDLGKHLAGVEDLLQLHELVEADIAVQAERVRAVSASALR---FCDPGKEYRPC----DPQLVSERVATLEQSYEALCELAATRRARLEESRRLWRFLWEVGEAEAWVREQQHLLASAETGRDLTGVLRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGANQASTRAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPEVGHDEFSTQALARQHRALEEEIRAHRPTLDALREQA-AALPPALSHTPEVQGRVPTLEQHYEELQARAGERARALEAALAFYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNALAARVTAVSDIAEQLLKASPPGKDRIIGTQEQLNQRWQQFRSLADGKKAALTSALSIQNYHLECTETQAWMREKTKVIESTQDLGNDLAGVLALQRKLAGTERDLEAISARVGELTQEANALAAGHPAQAPAINTRLGEVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRTLGEEVTRDQADP-QCLFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYFL---------SHTEMPGTLQAADAAIKKLEDFMSTMDANGERIRGLLEAGRQLVSKGNIHAEKIQEKADSIEKRHRKNQEAVQQLLGRLRDNREQQHFLQDCQELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMAELAANKDWLDKVDKEGRELTLEKPELKVLVSEKLEDLHRRWDELETTTQAKARSLFDANRAELFAQSCSALESWLESLQAQLHSDD----YGKDLTSVNILLKKQQMLEREMAVREKEVEAIQAQAKALAQED-QSAGEVERTSRAVEEKFRALCQPMKDRCRRLQASREQHQFHRDVEDEILWVTERLPM----ASSLEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADL-KERQRT-----LGTAAAGPELAELQEMWKRLSHELELRGKRLEEALRAQQFYRDAAEAEAWMGEQELHMMGQE-KAKDELSAQAEVKKHQVLEQALADYAQTIKQLAASSQDMIDHEHPESTRLTIRQAQVDKLYAGLKELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALARVQHKQ--QQLPDGTGRDLNAAEALQRRHCAYEHDIQALSTQVQQVQDDGLRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMDGINLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSACIDMGQELLARNHYAAEEISEKLSQLQSRRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQKSAVAWEERFSALEKLTALEERENEQKRKREEEERRKQPPTSEPMASQPEGSLVDGQRVLDTAWDGTQSKLPPSTQAPSINGVCTDTESSQPLLE------QQRLEQSNV--------PEGPGSGTGDESSGPRGERQTLPRGPAPSPMPQSRSSE-------SAHVATLPARGAELSAQEQ-------------MEGTLCRKQEMEAFNKKAANRSWQNVYCVLRRGSLGFYKDARAASAGVP--YHGEVPVSLARAQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEPVVPSASRGLTRAMTMPPVSQ 2360
BLAST of Spectrin beta chain vs. TrEMBL
Match: A0A5J4NLG0 (Spectrin beta chain OS=Paragonimus westermani OX=34504 GN=DEA37_0004144 PE=3 SV=1) HSP 1 Score: 1674.83 bits (4336), Expect = 0.000e+0 Identity = 975/2402 (40.59%), Postives = 1435/2402 (59.74%), Query Frame = 1
Query: 148 NALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEM-EKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEI-SLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTF--FKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHK-----GLKRFFSSIRLK 7305
N SDED+ + N T+K++ERSRIKALADERE VQKKTFTKW+NS L V+ IEDLY+DLRDGK LL LLE+LS E +P+PTRG+MRIHCLENVDK L FL +Q VHLENVGAHDIVDGNPRLTLGLIWTIILRFQ+QDI +E + + AKDALLLWCQMKTAGY +VN+RNFT SWR GL F ALIHKHRPDLI +S ++ D + NL AF++AE L + LLDP DV V PDE+S+ITYV +YYHYFN +KA +V +KR+ K++NQ +E E+MI Y+ L S+LLEWI TI LLN R FSNS+ G+Q Q+ FN YRT EKP KF EK LEVLLFTI+S + YNPPE ++ IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KA LRE+W+TDN L+ + + G +L V AA KKHEAIETDI+AY+E + + +++ LE E Y+D I ++ V+ LW LL +L RR LD LQ+ + E + I I + R +YGKHLM VE+L++ H LIE+DIR + R+E+++ +A ++ + +++E+ + +L D D R + L+ S +WQF D E++WIKE +M++PDLG+DLSSV RLLRKHK E E + L+N L G L++ + E IA + ++ LW+ LVD RK +L+E +++Q+++DCDDA+ W+ E +R + +G K++ TE L++ NQ+ + +++Y+ I+Q+ QA + Y D T+A +LD I+K Y D+ +A Q++LLDAL++Y+L + SD+VR W+TEK+K L +PSD+I ELEV++HRFE FE ELT AEKV VN LSE ++ +P+ I+ +QD LN SWN++AD+VD ++ +L Y Y+ F ++ +T WI+EK KLIES DELG DL +MQ QRR+ +QRD+ AIEAK++HL Q DE+ + +E + +H+ W L+++++DRD L +++ RF+Q LD F WL + QT++AS++IP + EAE L++K+ E++ E M+ G+ + D Q+ L R++ I +DW L+++ +++ + L++ +++ FF DA Q + L E+ L+K+ ++L + E + + EI +L ++ + +L G+ LI ++MQ KC L R RK L+EQ+ L E QD+DD ++ L EK + E K+ + KA E E++A + I ++ + G+Q P + +I L L W EL+ +K +A NRE LF+E+ +SMM W+ + QIV E G+ + LK D + EL +K+++LE++ H+E LK+Q P++ ++EQ+ +V++ + L PL ++ ++ QFL+D +DE DW+ +K+ LI + SK +LL QQL RH+ + NE+ N +++S+ QE ++MI ENH + + +++L L + + ++ + +L N++A Q++L D SE +W+ E+EL LMG +KD+Q ++K + + ++NY +I + ++ P+ K V+ + L+ +C E++ + + +YC E+ ++EAWI ER +A S + G D + C LLR+RF F+ ETN++G +V AN+ D LI H A I+ WKDR+NE WADLLELIDTRIQLLK+AWDLH++ D Q +L+ I EK SS + ++G+D K+V+ LQRK FE DL +L + + I +NTLLP Y DKE + +R E+I A+R L+ E RK++ L+ AD H F +MVREL W+E + +M + KPRDVSG+ELL+ NHRSLK E+D++EENFSICL+LGRTLL +H R +++ KC ++ +R L +W + L L++EVYQ+ARDA A+AW+++QE YL +++LG TLDETLALLKK + F++A QEE+F L+RLTT+E++++ E+T P TE + E + I + S +D RP S PV Q+ + P+ SK S +P P + +G L RKH+W++ +KA +R+WH LY +LS S T +K++R +EKP + Y+HE P+ L AAPA +Y KR VFR++ NG E LFQ S M WV AIN+ + P + + L S + P++Q G K+FF+ R K
Sbjct: 21 NYTSDEDDFESGNSTAKLYERSRIKALADEREVVQKKTFTKWVNSHLSVVSCNIEDLYLDLRDGKMLLKLLEILSGERLPQPTRGKMRIHCLENVDKSLNFLCDQHVHLENVGAHDIVDGNPRLTLGLIWTIILRFQIQDIIVEEYQTSETRCAKDALLLWCQMKTAGYHNVNVRNFTTSWRDGLAFNALIHKHRPDLIKYSELSKADPMKNLTNAFNVAEEKLHLTPLLDPSDVCVEQPDEKSIITYVVTYYHYFNKMKADTVHSKRIGKVVNQAIETEEMINQYEQLTSELLEWIEKTIELLNNRTFSNSLSGVQHQLAGFNTYRTIEKPPKFEEKGGLEVLLFTIRSKLRANNQTSYNPPEGRLIADINRAWEHLERAEHARELALRDELIRQEKLEQLASRFDRKAGLREAWLTDNQRLVAQDNFGQDLAAVEAATKKHEAIETDIFAYQERVNAMVNVAEELERENYHDQERIQLRRDNVMALWTNLLSSLSLRRHRLDLSLQLQHVFQEMAYLMDWIEEIKGRLRSVDYGKHLMGVEDLIQKHNLIEADIRVLGGRMEQVLQQAEPFITCAFPQEVGSYKPIEPEVVQERGRELRAAYEDLHDLKDTRLQGLQDSKKMWQFFWDMEDEKEWIKEKSQLMSSPDLGHDLSSVARLLRKHKALEEECKVHHVVLQNALKNGDKLIEEGNMSNEQIAQRIVEMNQLWDQLVDQIAERKQRLIESQEFFQFMADCDDADVWLSEQQRNASNEDVGLKLATTETLLKNNQEVINNLDDYQKTIDQLHQQAGIVSDYPDCDAATIASRLDAIDKHYADVQGLAKLRQQRLLDALSMYKLFDVSDTVRMWLTEKEKLLTTLVPSDEI-ELEVIRHRFECFEKELTANAEKVETVNKLSEGMLGTDHPDGSKILEHQDVLNASWNELADLVDRQKRQLDLAYQYNQFLIESTETANWIKEKAKLIESTDELGNDLSGIMQLQRRLGGLQRDLKAIEAKVEHLDNQADELRQAKPEHEPVVEAERQKIHELWNELKEMLKDRDDRLNYSSELQRFLQDLDHFQMWLRRTQTDVASEDIPNNLQEAEALVDKHKQLGAEISGYEDDFRRLMEFGRRETAGQTDA-QYEFLAKRLDLIEEDWDALHNMFDKRGEILDQNVEAHTFFRDALQADVNLAKLEQALVKE---------EIPTSLEAAQENIRQWEITQASLLMNDDKIDNILAHGQDLIDRKIFPMEKMQAKCDQLQNRRDSLKKRLDERKVVLEEQLKLLEFYQDVDDAEEWLTEKAVAVTEQPTPLAKNIALLYGRFKAFEGELDANKDKIAKVIEEGEQLMEVHPVLEPQIAPRLTALQHQWDELNTTAADKSAKMADANREILFDETAKSMMTWITEVSSQIVTTTEEVTEEIGLVELNEHLKDQDRKDQELLSKRRMLEDMATHAEKLKEQYPERQEEFEQVHQEVRIRLTELEAPLANRRDRLLKQKRVRQFLRDIEDEKDWIKDKLALIEDSSKLGN---SLLAAQQLLRRHRMLANEVENHRPRIESVCQEGEQMIQENHPRSDRFREAIDELWDLWGQLEQVVSDRHRKLLENEVA-QQYLFDASEAEAWMGEQELYLMGEE-RAKDEQGANNAMKKHEQRQKIVENYATEIRNLGERSRAMIETNHPEAEAVAAKQARVDKMYAGLRDLCVERRARLEEILKLYCLLREIL-DLEAWIAERIAVASSHELGADYEHCCLLRERFAEFARETNELGKCRVGAANELCDALIDQGHGEAAEIAGWKDRVNEAWADLLELIDTRIQLLKTAWDLHKFLSDCQDVLDRIAEKASS--IPEEVGRDAKAVATLQRKHGTFEYDLSRLGAQVEGLIEAANTLLPSYAADKERLICDRRDEVIHAWRQLQCSTEQRKVHLLDAADVHRFFAMVRELRMWMEVMRTEMATKEKPRDVSGVELLMNNHRSLKAEIDAREENFSICLSLGRTLLNRRHPREEDVREKCIQLVTERIQLTDQWTERWETLQLLLEVYQFARDAEVADAWLMAQEPYLASKDLGETLDETLALLKKHLAFERAVATQEERFVALQRLTTLELKAR----------------ERT----------PETEAARRAEKERRIAEAIREFLPPPVIPPVPVSEVD---------------------RPVSDSRISEPVSQIPST--PKRGRESKD-------------SGRP-------PRD--FEGVLTRKHEWQSGGKKAPSRSWHELYFILSASAGTLSAYKEQRLAREKPGELYRHESPVSLVGASAAPAFNYAKRRFVFRLKLSNGGETLFQARSEEAMHEWVQAINAVITSLPPGQPIESTSAAGGRAATLPSGVQPESQAGSSSVTTGKKKFFTLGRKK 2332
BLAST of Spectrin beta chain vs. TrEMBL
Match: A0A0X3PMM5 (Uncharacterized protein (Fragment) OS=Schistocephalus solidus OX=70667 GN=TR158569 PE=4 SV=1) HSP 1 Score: 1659.81 bits (4297), Expect = 0.000e+0 Identity = 956/2385 (40.08%), Postives = 1441/2385 (60.42%), Query Frame = 1
Query: 85 MEICVPYLNGNYCDSLSSDYQNALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGN-KAMIKEKRNSTIK-DFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNK-STDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPL-ESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPDEYKGIVKD--------------VEDNFNSLKIICAEKKTEI-SLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEI---IQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTF--FKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSAS 7167
MEI + N ++ + ++ N SDED+ + N T+K++ERSRIKALADERE VQKKTFTKW+NS L V IEDLY+DLRDGK LL LLE+LS E +PKPTRG+MRIHCLENVDK L FL +Q VHLENVGAHDIVDGN RLTLGLIWTIILRFQ+QDI +E + + AKDALLLWCQMKTAGY +VN+RNFT SWR GL F ALIHKHRPDLID++ ++ + NL AF +AE LGI LLDP DV V PDE+S+ITYV +YYH+FN LKA SV +KR+ K++NQ +E ++ Y+ L S LL WI+NTI LLN R F+NS+P +Q Q+ FN YRT +KP KF EK LEVLLFT++S + KVY P E S++ IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KA +RE+W+++N LL + + G++L V AA KKHEAIETDI AYEE + + +++ L+ E Y D I + VL LW+ LL L +RR L L++ + E +Q I I + + ++YGKHLM VE+LL+ H L+E+DIR ++ RL ++ +A F D +F NI+ + + EKR ++ + +L D RK L S +WQF D E++WIKE +M++PDLG+DLSSV+RLLRKH+ E E ++ + L GK L++ G+E + + +++++LW+ L D T RK +L E +++Q ++DCDDA+ W+ + +R+ + +G KMS TE L++ NQ+ ME +E YR+ + Q+ A + Y +D +A +LD ++K Y +++A Q++LLDAL++Y+L + SD+VR+WITEK+K L PSD+IEELEV++HRFE FE E+T AEKV +VN LS +L+ +P+ Q IV +QD LN +WN++AD+V+ ++ +L Y Y+ + ++C +T WI+EK LIES DELG DLE +MQ QRR++ +QRD+ AI+AKID++ Q D + +++ I+ + +H W+ L+ +I++RD L + +++ RF+Q D F WL +MQT +AS+++P + +EAEKL+ + R E+ M++G+ +++ D Q+V L R++ I ++W L + +++EK L++ L++ FF DA Q + I+N QE ++ K++ ++ +L E + +E F+ + + ++ + V+ G+ L +++Q KC L++R AQ R L +Q L QD+DD+++ + EK V ++ + ++ K E E++A + IE++ + G+Q + P + +I ++ L W +L+ ++ LA NRE LF+E+ +SM+ W+ I QIV E G+ + Q+K + EL K+K+LE++ H+E LK+Q P++ ++EQ+ +V++ + L P+ + + +A QK I QF +D +DE DW+ EK+ L+ + ++ +LL QQL+ RH+ + NE+ N +++++ E + MI+E H A V + +++L +L + + Q+ L Q++L D SE +W+ E+EL LM +KD+Q ++K + L+ I+NY +I SL D + +++ V+ + L +C E++ + + +Y E+ ++EAWI ERT IA S + G D + C LLR+RF FS ETN++G +VN AN+ D LI H A I+ WKDR+NE WADLLELI+TRIQLLK+AWDLH++ CD Q +L+ I EK + + D+G+D K+V++LQRK FE +L +L + + + TLLP Y DKE + +R E++ A+R L+ E RK++ L+ +D H F +MVREL W+E + +M + KPRDVSG+ELL+ NHRSL+ E+D++EENFSICL+LGRTLL H R EI+ KC ++ +R +L ++W + +HL L++EVYQ+ARDAA AEAW+I+QES++ + +LG +LDETLALLKK + F++A QEE+F L++LT +E+++ E+T E E + Q I+E + F Q +P P + A + V P + P + S+ + S P P+ ++ L+RKH+WE+ +KAS R+WH LY +LS + T +KD++H EKP Y E P+ L VA PA +Y KR VFR++ NG E LFQ S +M W++AIN+ S
Sbjct: 29 MEIQTLHQNLHWDQNSAAQANNYTSDEDDFESGNSTAKLYERSRIKALADEREIVQKKTFTKWVNSHLAVVNDHIEDLYLDLRDGKVLLKLLEILSGERLPKPTRGKMRIHCLENVDKSLNFLCDQHVHLENVGAHDIVDGNQRLTLGLIWTIILRFQIQDIIVEEYQTSETRCAKDALLLWCQMKTAGYNNVNVRNFTTSWRDGLAFNALIHKHRPDLIDYAKLSKASPLQNLQNAFSVAEEKLGITPLLDPADVCVEQPDEKSIITYVVTYYHFFNKLKADSVHSKRIGKVVNQAIESSELTNQYERLTSDLLTWIQNTIELLNDRVFANSLPDVQHQLAGFNTYRTIDKPPKFAEKGALEVLLFTLQSKMRANNQKVYTPTEGKSIADINRAWENLERAEHARELALRDELIRQEKLAQLATRFDRKAGMREAWLSENQRLLAQYNFGSDLAAVEAATKKHEAIETDISAYEERVNAVVSVAEELQLENYYDNDRIQARRETVLRLWQNLLDLLRKRRSCLALSLELQHVFQEMSYLQDWIDEIGNRLKSEDYGKHLMGVEDLLQKHGLLEADIRVLDGRLNHVLEQAQ---VFIDCNFPDNIDYRPIEPDVVEKRGRDLRAAYDQLHDLAATRKHALDDSRKMWQFFWDMDDEKEWIKEKSQLMSSPDLGHDLSSVERLLRKHRALEEECQTRHGVFQASLDSGKKLIEEDNRGKENVQRRIDEMRDLWDQLADQTAERKQRLQESQEFFQLMADCDDADAWLLDQQRIASNEDVGVKMSTTESLLKINQELMENLEAYRETVNQLHATAAKVSDYPDIDGGMIASRLDGVDKNYSKAIELAKLRQQRLLDALSMYKLFDVSDTVRTWITEKEKLLTTLCPSDEIEELEVIRHRFECFEKEMTSNAEKVGNVNKLSASLLDKDHPDAQQIVVHQDTLNATWNELADLVEKQKGQLDLAYQYNQYLIECTETANWIKEKEHLIESTDELGNDLEGIMQLQRRLSGLQRDLQAIQAKIDYVDEQADLLEAAKPEASEVIQTERKKLHDLWDELKDMIKERDDRLNDSSELQRFLQDFDHFQMWLRRMQTTVASEDVPNTLTEAEKLVQDHEQVRMEIDGYADDFNRLMEMGRKVTENQTDP-QYVYLAQRLDVIAENWDALQKMCDDREKVLKQDLEAQTFFRDAIQSDVIINKQENFVSKEV----------PTSPEALQEAIQSHESFMAALPASDEKIDHVIAVGRELAARGVFPTEKIQLKCDQLEQRRAAVKQKAQERSALLAQQGQLQGFCQDVDDVEEWIAEKNIVAQAAPPPRDQFGIAAIYSKFKTFESELDANKDKIEKVIQAGEQLMLEQPELQAQIEPRVEVLRRQWDDLNTQAVDQSAKLADSNREALFDETAKSMLTWITEISSQIVTTTEEVTEEVGLVELNEQIKDQEKKEQELVAKRKMLEDMATHAEKLKEQYPERKDEFEQVHREVRIRLTELEAPMADRRERLAKQKRI-RQFFRDLEDEKDWVREKLQLLEDSNRLGN---SLLSCQQLKRRHRMLANEVDNHHPRIEAICNEGETMINEGHPHAANVREGIDELHALWADLQKAVAARQDALDLNEVAQQYLFDASEAEAWMGEQELYLMS-SEKAKDEQGANSAMKKHELLQKTIENYAGEIR-------SLGDRSRAMIEGNHPEAEAVASKQSRVDRMYAGLHDLCLERRLRLEEILKLYSLLREIL-DLEAWIAERTVIASSHEMGADYEHCCLLRERFAEFSRETNELGKHRVNAANELCDALITQGHGEAAEIASWKDRVNEAWADLLELIETRIQLLKAAWDLHKFLCDCQDVLDRIAEKAGA--IPEDVGRDAKAVAVLQRKHIAFESELTRLGQQVEEVVEFATTLLPSYAGDKERIICDRRDEVVQAWRQLQYSAEQRKVHLLDASDVHRFFAMVRELRLWMEMMQTEMSSKEKPRDVSGVELLMNNHRSLEAEIDAREENFSICLSLGRTLLNRNHPRQEEIREKCIQLVTERILLSEQWNDRWEHLKLILEVYQFARDAAVAEAWLIAQESFIKSSDLGESLDETLALLKKHLAFERAAATQEERFLALQKLTHLELKAS----------------ERTPESEAARLELRKQKISEATREF---------------------------------------------QPPKQPVPLTPAQASVAAAGVGSAPGRPGVETPT-SRSIRESIDSGRPPPSN----------LEALLHRKHEWESATKKASARSWHELYFVLSAATGTLSAYKDQKHAHEKPGDLYHKEAPVSLAGAVAVPATNYEKRMYVFRLKLENGGESLFQARSDDEMHNWIEAINAIS 2312
BLAST of Spectrin beta chain vs. TrEMBL
Match: G4VDE6 (Spectrin beta chain OS=Schistosoma mansoni OX=6183 GN=Smp_143470.2 PE=3 SV=1) HSP 1 Score: 1659.43 bits (4296), Expect = 0.000e+0 Identity = 950/2411 (39.40%), Postives = 1433/2411 (59.44%), Query Frame = 1
Query: 148 NALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKD--------IQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNI---EAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTF--FKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQ-----HHKGLKRFFSSIRLK 7305
N SDEDE + N T+K++ERSRIKALADERE VQKKTFTKW+NS L V+ IEDLY+DLRDGK LL LLE+LS E +P+PTRG+MRIHCLENVDK L FL +Q VHLENVGAHDIVDGN RLTLGLIWTIILRFQ+QDI +E + + AKDALLLWCQMKTAGYP+VN+RNFT SWR GL F ALIHKHRPDLI++S ++++ I NL AF +AE L + LL+P DV V PDE+S+ITYV +YYHYFN +KA +V +KR+ K++NQ +E + MI Y+ L S LL+WI+ TI+LL+ R F+NS+ G+Q Q+ FN YRT EKP KF EK LEVLLFTI+S + + YNPPE ++ IN AW+ L AE+ RE A+R EL+RQEKL LA +F++KA +RE+W+TDN L+ ++ G+NL V AA KKHEAIETDIYAYEE + + +++ L+ E Y+ +I ++KVL +W+ LL +L RR+HL+ LQ+ + E + I I ++ + +YGKHLM VE+LL+ H L+E+DIR + R+ +++ +A ++ +++E+ + +L D + R L+ S +WQF D E++WIKE +M++PDLG+DLSSV RLLRKHK E E R LE+ L G+ L+ G E I+ + ++ LW LVD RK +L+E D++Q ++DCDDA+ W+ + +R+ + +G K + T L++ NQ+ M+ ++NY++ I Q+ A + Y D +A +LD +++ Y + ++ ++L DAL++Y+L +DSD+VR+WITEK+K L +PSD+IEELEV++HRFE FE E+ A+KV VN LSE ++ +P+ + I+ +QD LN SWN++AD+VD ++ +L Y Y+ F ++ +T WI++K KLIES DEL +LE +MQ QRR+ +QRD+ AIEAK+ HL Q E+ + + + + +H W L++++++RD L + +++ RF+Q LD F WL + Q +AS+ +P + EAE L++++ + E+ E M G+ + + D Q++ L R++ I ++W+ L + E + L++ +++ FF DA Q E +L EK + K+ Q + NF T +++L+ +E ID +L+D G L+ +++QNKC+ L +R KLKEQ+ L E QD+DD ++ L EK + E +S + + KA E E++A + I ++ + G++ P + ++ + L W +L+ +K +A NRE LF+E+ +SM+ W+ + QIV E G+ I LK + + EL K+++L+++ H+E LK+Q P++ ++EQ+ +V++ + L PL + ++ QFL+D +DE DW+ EK+ LI + K +LL QQL RH+ + NE+ N ++D++ E ++MI E H + + +++L E L + + Q L+ Q++L D SE +W+ E+EL LMG +KD+Q I+K + L+ ++NY +I + C +L P+ + K ++ + L+ +C+E++ + + Y L ++I EAWI ER +A S + G D + C LLR+RF FS ETN++G +++ AN+ + LI H A I+ WKDRINE WADLLELIDTRIQLLK+AWDLH++ D Q +L+ I +K SS + ++G+D K+V+ LQRK FE +L +L S + + +N+LLP Y DKE + +R E+I A+R L+ E RK + +D H F SMVREL W++ + ++M + KPRDVSG+ELL+ +HRSL E+D++EENFSICL+LGRTLL +H + E+++KC ++ ++ +L +W + LSL++EVY++ARDA A+ W+ SQE+YLNN +LG TLDETLALLKK F++A QEE+F +L++LTT+E++++ E+T P TE + E + I ++ Q + + + V+ R +R Q S+ P + R S++ KP VS D +G L RKH+WE +KAS+R+WH LY +LS + T +K++RH KE+P Y+HE+P+ L AAPA +Y KR VFR++ NG E LFQ S DM WV AIN+ + P+ ++ S L S + P++Q G K+FF+ R K
Sbjct: 21 NYTSDEDEFESGNSTAKLYERSRIKALADEREVVQKKTFTKWVNSHLSVVSCNIEDLYLDLRDGKMLLKLLEILSGERLPRPTRGKMRIHCLENVDKSLNFLCDQHVHLENVGAHDIVDGNSRLTLGLIWTIILRFQIQDIIVEEYQTSETRCAKDALLLWCQMKTAGYPNVNVRNFTTSWRDGLAFNALIHKHRPDLIEYSKLSKSEPIKNLTTAFSVAEEKLNLHPLLEPSDVAVEQPDEKSIITYVVTYYHYFNKMKADTVHSKRIGKVVNQAIETDDMINQYEQLTSDLLDWIKKTIKLLDDRTFANSLSGVQHQLAGFNTYRTVEKPPKFREKGGLEVLLFTIRSKMRANNQRQYNPPEGKMIADINRAWEMLERAEHARELAVRDELIRQEKLEQLASRFDRKAGMRETWLTDNQRLVLQEFFGDNLAAVEAATKKHEAIETDIYAYEERVNAMVNVAEELKRENYHAHENIQLRRDKVLAMWRNLLDSLSIRRQHLELSLQLQHIFQEMTYLMDWIEEIKSRLKSQDYGKHLMGVEDLLQKHNLLEADIRVLGGRMNQVVDQATPFIVGSFTPDMGAYKPIEPEIVQERTEKLRAAYDDLHDLAEARLRGLRDSREMWQFFWDMEDEKEWIKEKSQLMSSPDLGHDLSSVSRLLRKHKALEEECQMHRAVLEDALKHGEQLITDGNQGYEQISQRIVEMNQLWGQLVDLITERKQRLIESQDFFQLMADCDDADVWLTDQQRIVSNEDVGLKQATTVSLLKNNQEVMDNLQNYQETISQLNQDASRVSDYPDSDATAIAHRLDAVDQHYALVKELCRLRHKRLNDALSMYKLFDDSDTVRTWITEKEKLLTTLVPSDEIEELEVIRHRFECFEKEMAGNAKKVGSVNLLSEEMLDKAHPDAEKILRHQDELNASWNELADLVDKQKRQLDLSYQYNQFLIESSETANWIKDKAKLIESTDELDNNLEGIMQLQRRLGGLQRDLNAIEAKVKHLDEQAQELTEAKPETQAVVIAEKEKIHDLWNELKEIVKERDDRLNDSSELQRFLQDLDHFQIWLRRTQITVASEEVPNNLEEAETLLDQHEQLKAEIDGYESDFHRLMDFGRRVTEVQTDA-QYMFLAQRLDGIEENWEALRRMYENRTSALQEGVEAQTFFRDALQAEVLLAKMEKVVSKEEAPTNLEMAQENLRNFETFRTSLVPTDEK-------IDNVLND----------GAKLVDRGIFPTEKIQNKCEQLKQRRDSLKRRTDEHGQKLKEQLHLQEFCQDVDDAEEWLSEKAMAITEQPAPIARSIAALYGRFKAFEGELDANKEKIAKVIEEGEELIVAHPMLQVQVEPKISALRKQWEDLNTTTADKSAKMADANRETLFDETAKSMLTWITEVSSQIVTTTEEVTEEIGLVEINEHLKDQERKDQELAAKRRMLQDMATHAEKLKEQYPERREEFEQVHQEVRIRLTELEAPLADRRDRLVKQKRVRQFLRDIEDEKDWIKEKLALIEDSCK---LGSSLLATQQLIRRHRMLSNEVDNHRPRIDAVCHEGEQMILEGHPRSDRFREAIDELWVLWEQLQHVVGERQEQLARNEVAQQYLFDASEAEAWMGEQELYLMGDE-RAKDEQGANNAIKKHEQLQKTVENYATEIRGLGERCQALLEANHPESEAVVAKQARIDKMYAGLRDLCSERRARLDEIL---KLYHLLRDILDLEAWIAERILVASSHEVGADYEHCCLLRERFAEFSRETNELGKYRISAANELCNALIGQGHSEAAEIASWKDRINEAWADLLELIDTRIQLLKTAWDLHKFLADCQDVLDRIVDKVSS--IPEEVGRDAKAVAALQRKHNTFECELARLGSRVEGIVEAANSLLPSYAADKERLICDRRDEVIHAWRQLQCSAEQRKARLHDASDVHRFFSMVRELRLWMDTIRMEMTTKEKPRDVSGVELLMNSHRSLMAEIDAREENFSICLSLGRTLLNRRHPQEEEVRNKCIQLVTEKILLNDQWAERWETLSLLMEVYEFARDAEIADTWLTSQEAYLNNTDLGETLDETLALLKKHFAFERAAATQEERFRELEKLTTLELKAR----------------ERT----------PETEAARQLEKERKIAEAVKEFQPPPPPVSVPVQTPVSE-----------VDRRAVDIRDAEQGSSRLPTVTTPRHGRG-SSDVGKP-----VSRD--------------------FEGVLTRKHEWETGTKKASSRSWHELYFVLSATSFTLSAYKEQRHAKERPGDLYRHELPVNLVGASAAPAYNYAKRRFVFRLKLSNGGESLFQAHSEEDMHSWVQAINAVASSA-SGQPTESSSSAGGRAATLPSGVAPESQVASSSSATGKKKFFTLGRKK 2340
BLAST of Spectrin beta chain vs. TrEMBL
Match: A0A094ZSL4 (Spectrin beta chain OS=Schistosoma haematobium OX=6185 GN=MS3_05505 PE=3 SV=1) HSP 1 Score: 1656.34 bits (4288), Expect = 0.000e+0 Identity = 948/2411 (39.32%), Postives = 1432/2411 (59.39%), Query Frame = 1
Query: 148 NALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKD--------IQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNI---EAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTF--FKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQ-----HHKGLKRFFSSIRLK 7305
N SDEDE + N T+K++ERSRIKALADERE VQKKTFTKW+NS L V+ IEDLY+DLRDGK LL LLE+LS E +P+PTRG+MRIHCLENVDK L FL +Q VHLENVGAHDIVDGN RLTLGLIWTIILRFQ+QDI +E + + AKDALLLWCQMKTAGYP+VN+RNFT SWR GL F ALIHKHRPDLI++S ++++ I NL AF +AE L + LL+P DV V PDE+S+ITYV +YYHYFN +KA +V +KR+ K++NQ +E + MI Y+ L S LL+WI+ TI+LL+ R F+NS+ G+Q Q+ FN YRT EKP KF EK LEVLLFTI+S + + YNPPE ++ IN AW+ L AE+ RE A+R EL+RQEKL LA +F++KA +RE+W+TDN L+ ++ G+NL V AA KKHEAIETDIYAYEE + + +++ L+ E Y+ +I ++KVL +W+ LL +L RR+HL+ LQ+ + E + I I ++ + +YGKHLM VE+LL+ H L+E+DIR + R+ +++ +A ++ +++E+ + +L D + R L+ S +WQF D E++WIKE +M++PDLG+DLSSV RLLRKHK E E R LE+ L G+ L+ G E I+ + ++ LW LVD RK +L+E D++Q ++DCDDA+ W+ + +R+ + +G K + T L++ NQ+ M+ ++NY++ I Q+ A + Y D +A +LD +++ Y + ++ ++L DAL++Y+L +DSD+VR+WITEK+K L +PSD+IEELEV++HRFE FE E+ A+KV VN LSE ++ +P+ + I+ +QD LN SWN++AD+VD ++ +L Y Y+ F ++ +T WI++K KLIES DEL +LE +MQ QRR+ +QRD+ AIEAK+ HL Q E+ + + + + +H W L++++++RD L + +++ RF+Q LD F WL + Q +AS+ +P + EAE L++++ + E+ E M G+ + + D Q++ L R++ I ++W+ L + E + L++ +++ FF DA Q E +L EK + K+ Q + NF T +++L+ +E ID +L+D G L+ +++QNKC+ L +R A KLKEQ+ L E QD+DD ++ L EK + E +S + + KA E E++A + I ++ + G++ P + ++ + L W +L+ +K +A NRE LF+E+ +SM+ W+ + QIV E G+ I LK + + EL K+++L+++ H+E LK+Q P++ ++EQ+ +V++ + L PL + ++ QFL+D +DE DW+ EK+ LI + K +LL QQL RH+ + NE+ N ++D++ E ++MI E H + + +++L E L + + Q L+ Q++L D SE +W+ E+EL LMG +KD+Q I+K + L+ ++NY +I + C +L P+ + K ++ + L+ +C+E++ + + Y L ++I EAWI ER +A S + G D + C LLR+RF FS ETN++G +++ AN+ + LI H A I+ WKDRINE WADLLELIDTRIQLLK+AWDLH++ D Q +L+ I +K SS + ++G+D K+V+ LQRK FE +L +L S + + +N+LLP Y DKE + +R E+I A+R L+ E RK + +D H F SMVREL W++ + ++M + KPRDVSG+ELL+ +HRSL E+D++EENFSICL+LGRTLL +H + E++ KC ++ ++ +L +W + LSL++EVY++ARDA A+ W+ SQE+YLNN +LG TLDETLALLKK F++A QEE+F +L++LTT+E++++ E+T P TE + E + I + +R F + + + + + R +R Q S+ P + +R S++ KPV P+ +G L RKH+WE +KAS+R+WH LY +LS + T +K+++H KE+P Y+HE+P+ L AAPA +Y KR VFR++ NG E LFQ S M WV AIN + P ++ S L S + P++Q G K+FF+ R K
Sbjct: 21 NYTSDEDEFESGNSTAKLYERSRIKALADEREVVQKKTFTKWVNSHLSVVSCNIEDLYLDLRDGKMLLKLLEILSGERLPRPTRGKMRIHCLENVDKSLNFLCDQHVHLENVGAHDIVDGNSRLTLGLIWTIILRFQIQDIIVEEYQTSETRCAKDALLLWCQMKTAGYPNVNVRNFTTSWRDGLAFNALIHKHRPDLIEYSKLSKSEPIKNLTTAFSVAEEKLNLHPLLEPSDVAVEQPDEKSIITYVVTYYHYFNKMKADTVHSKRIGKVVNQAIETDDMINQYEQLTSDLLDWIKKTIKLLDDRTFANSLSGVQHQLAGFNTYRTVEKPPKFREKGGLEVLLFTIRSKMRANNQRQYNPPEGKMIADINRAWEMLERAEHARELAVRDELIRQEKLEQLASRFDRKAGMRETWLTDNQRLVLQEFFGDNLAAVEAATKKHEAIETDIYAYEERVNAMVNVAEELKRENYHAHENIQLRRDKVLAMWRNLLDSLSIRRQHLELSLQLQHIFQEMTYLMDWIEEIKSRLKSQDYGKHLMGVEDLLQKHNLLEADIRVLGGRMNQVVDQATPFIVGSFTPDMGTYKPIEPEIVQERTEKLRAAYDDLHDLAEARLRGLRDSREMWQFFWDMEDEKEWIKEKSQLMSSPDLGHDLSSVSRLLRKHKALEEECQMHRAVLEDALKHGEQLITDGNQGGEQISQRIVEMNQLWGQLVDLITERKQRLIESQDFFQLMADCDDADVWLTDQQRIVSNEDVGLKQATTVSLLKNNQEVMDNLQNYQETISQLNQDASRVSDYPDSDATAIAHRLDAVDQHYALVKELCRLRHKRLNDALSMYKLFDDSDTVRTWITEKEKLLTTLVPSDEIEELEVIRHRFECFEKEMAGNAKKVGSVNLLSEEMLDKAHPDAEKILRHQDELNASWNELADLVDKQKRQLDLSYQYNQFLIESSETANWIKDKAKLIESTDELDNNLEGIMQLQRRLGGLQRDLNAIEAKVKHLDEQAQELTEAKPETQAVVIAEKEKIHDLWNELKEIVKERDDRLNDSSELQRFLQDLDHFQIWLRRTQITVASEEVPNNLEEAETLLDQHEQLKAEIDGYENDFHRLMDFGRRVTEVQTDA-QYMFLAQRLDGIEENWEALRRMYENRTAALQEGVEAQTFFRDALQAEVLLAKMEKVVSKEEAPINLEMAQENLRNFETFRTSLVPTDEK-------IDNVLND----------GAKLVGRGIFPTEKIQNKCEQLKQRRDSLKRRADEHGQKLKEQLHLQEFCQDVDDAEEWLAEKAMAITEQPAPIARSIAALYGRFKAFEGELDANKEKIAKVIEEGEELIVAHPMLQVQVEPKISALRKQWEDLNTTTADKSAKMADANRETLFDETAKSMLTWITEVSSQIVTTTEEVTEEIGLVEINEHLKDQERKDQELAAKRRMLQDMATHAEKLKEQYPERREEFEQVHQEVRIRLTELEAPLADRRDRLVKQKRVRQFLRDIEDEKDWIKEKLALIEDSCK---LGSSLLATQQLIRRHRMLSNEVDNHRPRIDAVCHEGEKMILEGHPRSDRFREAIDELWVLWEQLQHVVGERQEQLTRNEVAQQYLFDASEAEAWMGEQELYLMG-DERAKDEQGANNAIKKHEQLQKTVENYATEIRGLGERCQALLEANHPESEAVVAKQARIDKMYAGLRDLCSERRARLDEIL---KLYHLLRDILDLEAWIAERILVASSHEVGADYEHCCLLRERFAEFSRETNELGKYRISAANELCNALIGQGHSEAAEIASWKDRINEAWADLLELIDTRIQLLKTAWDLHKFLADCQDVLDRIVDKVSS--IPEEVGRDAKAVAALQRKHNTFECELARLGSRVEGIVEAANSLLPSYAADKERLICDRRDEVIHAWRQLQCAAEQRKARLHDASDVHRFFSMVRELRLWMDTIRMEMTTKEKPRDVSGVELLMNSHRSLMAEIDAREENFSICLSLGRTLLNRRHPQEEEVRKKCIQLVTEKILLNDQWAERWETLSLLMEVYEFARDAEIADTWLTSQEAYLNNTDLGETLDETLALLKKHFAFERAAATQEERFRELEKLTTLELKAR----------------ERT----------PETEAARQLEKERKI-------SEAVREFQPPPPPVSVPVQTPVS----EADRRAVDIRDAEQGSSRLPTVTTPRHERG-SSDVGKPV-------------PRD------------FEGVLTRKHEWETGTKKASSRSWHELYFVLSATSFTLSAYKEQKHAKERPGDLYRHELPVNLVGASAAPAYNYAKRSFVFRLKLSNGGESLFQAHSEKHMHSWVQAINVVASSA-SGQPMESSSSAGGRAATLPSGVAPESQVASSSSAPGKKKFFTLGRKK 2340
BLAST of Spectrin beta chain vs. TrEMBL
Match: A0A5K3ET41 (Spectrin beta chain OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 1646.33 bits (4262), Expect = 0.000e+0 Identity = 952/2418 (39.37%), Postives = 1446/2418 (59.80%), Query Frame = 1
Query: 85 MEICVPYLNGNYCDSLSSDYQNALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKE---KRNSTIKDFHELLDSL-DKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVKD--VEDNFNSLKIICAEKKTEI-SLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHE---IIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTF--FKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQ--------SHPNLSSSLPPQAQH 7263
MEI + N ++ S + N +SD+D+ + N T+K++ERSRIKALADERE VQKKTFTKW+NS L V ++EDLY+DLRDGK LL LLE+LS E +PKPTRG+MRIHCLENVDK L FL +Q VHLENVGAHDIVDGN RLTLGLIWTIILRFQ+QDI +E + K AKDALLLWCQMKTAGY +VN+RNF+ SWR GL F ALIHKHRPDLI++ + + NL AF +A+ LGIP LLD DV V PDE+S+ITYVA+YYHYFN +KA +V +KR+ K++NQ +E Q+I Y+ L S+LL WI+ TI LLN R F+NS+P +Q Q+ FN YRT +KP KFVEK LEVLLFT++S + KVY+PP+ +S IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KA +RE+W+++N L+ + + G++L V AA KKHEAIETDI AY E + + +++ L+ E Y D I + VL LW LL L +RR L+ LQ+ + E +Q I I + + ++YGKHLM V++LL+ H L+E+DIR ++ RL +++ +A +V D +F N+ G + + E KR ++ +E L L D R++ L+ S +WQF D E++WIKE +M++PDLG+DL+SV+RLLRKH+ E E ++ N ++ G L++ G+E I + +++ LW+ L D T RK +L E +++Q ++DCDDA+ W+ + +R+ + +G KMS TE LI+ NQ+ ME +E YR+ I + A + Y D + +LD +++ Y L++A + Q++LLDAL++Y+L + SD+VR+WITEK++ L PSD I+ELEV +HRFE FE E+TK AEKV VN LSENL+ +P+ Q IV QD LN +WN +AD+V+ ++ + + + Y+ + ++CQ+T WI++K LIES DELG DLE +MQ QRR++ +QRD+ AI+AKIDHL Q D ++ A+ I + +H W+ L++++++RD L + +++ RF+Q LD F WL + Q +AS+++P + EAEKL+ + + E+ E + M++G+ ++++ D Q++ L R++ I ++W L+ + E+++K L++ +++ FF DA ++K++N QE + K++ S + + + NL F M ++++ ++ V+ G+ L +++ KC L++R + A +R+ KL + L +QD+DD+++ + EK + + + K E E++A + IE++ G+ A+ P + EI ++ L W +L+ +E+ LA NRE LF+E+ +SM+ W+ + QIV E G+ + Q+K + EL K+K+LE++ H+E LK+Q PD+ ++EQ+ +V++ + L P+ ++ ++ QF +D +DE DW+ EK+ +I + + M T +LL QQ+Q RHK + NE+ N ++D++ Q+ + MI + H + +++++ +L ++ Q L Q++L D SE +W+ E+EL LMG ++D+Q ++K + L+ I+NY +I C ++ P+ K V+ + L +C E++ + + +Y E+ ++EAWI ERT IA S + G D + C LLR+RF FS ETN++G +V AN+ D LI H A I+ WKDR+NE WADLLELI+TRIQLLK+AWDLH++ CD Q +L+ I EK S + D+G+D K+V++LQRK +E +L +L + + +N LLP Y DKE+ + +R E++ A+R L+ E RK++ L+ +D H F +MVREL W+E + +M ++ KPRDVSG+ELL+ NH+SLK E+D+++ENFSICL+LGRTLL +H R EI+ KC ++ +R I+ ++W + ++L LM+EVY +ARDAA AEAW+I+QES++ + +LG +LDETLALLKK + F+KA QEE+F L++LTT+E+++K E+T E E I Q I + + F+ P +P +G R+ P +S + + S RP P N+ +H RK++WE ++A R+W LY +L + T +KD R +KP Y P+ L VAAPA DY KRP VFR++ NG E LFQ S +M WV+ INS S + P P+T + S S++LP A H
Sbjct: 1 MEIQALHQNLHWEPSSVAQPNNYISDDDDFESGNSTAKLYERSRIKALADEREIVQKKTFTKWVNSHLAVVNHRVEDLYLDLRDGKHLLRLLEILSGERLPKPTRGKMRIHCLENVDKSLNFLCDQHVHLENVGAHDIVDGNQRLTLGLIWTIILRFQIQDIIVEEYQTSETKCAKDALLLWCQMKTAGYNNVNVRNFSTSWRDGLAFNALIHKHRPDLIEYQKLTKATPLQNLQNAFTVADEKLGIPPLLDANDVCVEQPDEKSIITYVAAYYHYFNKMKADTVHSKRIGKVVNQAIESSQLIDQYEQLTSELLTWIQKTIELLNDRVFANSLPDVQHQLAGFNTYRTVDKPPKFVEKGALEVLLFTLQSKMRANNHKVYSPPDGKLISDINRAWENLEKAEHARELALRDELIRQEKLSQLATRFDRKAGMREAWLSENQRLVAQYNFGSDLAAVEAATKKHEAIETDISAYAERVNAVVSVAEELQLENYYDNDRIQMRRENVLRLWSNLLDLLRKRRACLNLSLQLQRVFQEMSYLQDWIDEIGNRLKSEDYGKHLMGVDDLLQKHNLLEADIRVLDDRLTQVLDQAKVFV---DCNFPENV-EGYRPIEPEFVQKRGEDLRAAYEKLHELADARRQALEDSRKMWQFFWDMDDEKEWIKEKSQLMSSPDLGHDLTSVERLLRKHRALEEECKIRQNVFNNSVVTGNNLINEGNRGKEAIQQRIDEMHELWDQLADVTAERKQRLQESQEFFQLMADCDDADAWLIDQQRIASNEDVGLKMSTTESLIKINQELMENLEQYRETINLLHVTAAKVSEYPDSDSTIIGSRLDNVDENYNRALELAKQRQQRLLDALSMYKLFDVSDTVRTWITEKERLLATLCPSDVIQELEVTRHRFECFEKEMTKNAEKVSSVNKLSENLIKTDHPDSQQIVIRQDKLNATWNGLADLVEKQKCRIETAHQYNQYLLECQETACWIKDKKNLIESTDELGNDLEGIMQLQRRLSGLQRDLQAIQAKIDHLDEQADVLVVTKPEEAEAIRAERMKIHDLWDELKEMLKERDDRLNDSSELQRFLQDLDHFQVWLRKAQVTVASEDVPNTLPEAEKLLQNHEQFKPEIDGYEDDFKRLMEMGRRVVENQSDP-QYLFLAERLDGIEENWVALHKMYEDRDKVLKQDVEAQSFFRDATLMDKLINKQEALISKEVVSTPESVDEALRNL----------NTFQAAMPANDEKISQVIAVGRDLAARGVFPVEKILAKCDQLEQRRQAVKEKAIDREAKLAQHSRLQGFVQDVDDVEEWISEKTILAQHAPPPRGAGIAAIYGKFKTFESELDANKDKIEKVIATGEHLIAEQPQLQAEIEPRIEVLRRQWVDLNNQAQEQSAKLADSNREALFDETAKSMLTWITEVSSQIVTTTEEVTEEVGLVELNEQIKDQERKEQELMAKRKMLEDMAKHAEKLKEQYPDRKDEFEQVHQEVRIRLTELEAPMANRRDRLTKQKRVRQFFRDLEDEKDWIREKLAIIEDHGR-MGT--SLLSNQQMQRRHKMLANEVDNHQPRIDAVCQQGEEMIADGHPHSEKFREGIDEVRALWASLRLALDDRQAALLQNEVAQQYLFDASEAEAWMGEQELYLMGDE-KARDEQGATNAMKKHELLQKTIENYASEIRSLGDRCRAMVESGHPESEVVAAKQSRVDKMYAGLHDLCLERRLRLEEILKLYSLLREIL-DLEAWIAERTVIASSHEMGADYEHCCLLRERFADFSKETNELGKLRVASANELCDALIAQGHGEAAEIASWKDRVNEAWADLLELIETRIQLLKAAWDLHKFLCDCQDVLDRIAEK--SGIIPEDVGRDAKAVAVLQRKHAAYEAELSRLGQQVEEVVDFANNLLPSYAGDKESIICDRRDEVVQAWRQLQYAAEQRKIHLLDASDVHKFFAMVRELQLWMEAMRTEMTIKEKPRDVSGVELLMNNHKSLKAEIDARKENFSICLSLGRTLLNRRHPREEEIREKCIQLVTERVIMLEQWNDRNENLQLMLEVYHFARDAAVAEAWLIAQESFVKSPDLGESLDETLALLKKHLAFEKAVATQEERFIALEKLTTLELKAK----------------EKTPESEAARKKAIEQKIVDASREFQPLPSTSQP-----------------------AVPSGPMHGTPLRRGFETPTGRS-----LRESVDSGRPTPRNLEALLH---------------------------------RKNEWETTVKRAFGRSWVELYFVLDATLGTLSAYKDSRSAHDKPGHLYHKVPPVNLAGAVAAPATDYDKRPYVFRLKLPNGGESLFQCLSEDEMHTWVETINSVSASL--PAPVKVMPTTEEEEAEGGLVSPAGRSATLPSTALH 2317
BLAST of Spectrin beta chain vs. Ensembl Cavefish
Match: sptbn2 (spectrin beta chain, non-erythrocytic 1-like [Source:NCBI gene;Acc:103032213]) HSP 1 Score: 1308.12 bits (3384), Expect = 0.000e+0 Identity = 811/2401 (33.78%), Postives = 1340/2401 (55.81%), Query Frame = 1
Query: 154 LSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNF-IPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXD-HSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKII----AEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDS---EIKDTGYFQKVNSRQSMM-----RPFPQSSALS-----PVP---QMKQSKRPQPSNMSKPVHNLSVSTDMLSAS---PKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEK-PKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPP 7251
L+ E E N ++++FERSRIKALADERE VQKKTFTKW+NS L VT +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VN+ NFT SWR GL F A++HKHR DLI+F + R++ NL AF++AE LG+ LLDPEDVNV PDE+S+ITYVA+YYHYF+ +KA +V KR+ K+L+ +E +Q+I+ Y++L S+LL+WI TI LN RQ +NS+ +Q Q+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KAA+RE+W+++N L+ + + G +L V AA +KHEAIETDI AY E + + ++ LE E Y+++ I+ K+ VL LW+ L + L RRE L + + L+ E + + + + + + GKHL +VE+LL+ H L+E+DI + +R+ + + A R+ D+ A+++EK + K + EL +R+ L+ S +WQF+ + E WI+E I+++ D G DLSS LL KH+ F E++++ L N + G+ LV G + + DI+ W L ++++ R+ L E + +Q+ +D +D E WI E R + +G T+ L RK ++ E ++++R I+ + QA++L + V +L IE++Y++L ++ ++ L AL +YR+ +++ + + WI EK+++L N IPS +E+LEV++ RFE E E+ ++ VN +SE L+ + N N + I QD LNN W++ + D ++ L S + N+ ++C + W++EK K+IES LG DL VM QR++ M+RD+ AI+ K+ L ++ +++ + A +I +L+ + + WE L+ ++ R+ +L + + F++ LDDF WL + QT +AS++ P S +EAE+L+ ++ + ++E+ + E+ G + + + D Q++ L R+++++ W L + E + L + F DA+Q E LN+QE L + ++L E + ++E F+ M + E+ + V++ G+ L+ + N D++Q K ++ ER +KN A + KLK+ L LQD +L + EK+ ++S ++ S + +A E+ + + +++++K G+ + P ++ + + L L W EL + K Q L NR +LF +S ++ WL+NI + +DD +TS+ LKK H M + + ++ S+ L D + +++ Q + D + L+ L+ Q+++ A QF +D +DEI W+ E++ L + K + ++ L++ ++++++ EI+ ++D + + M E +RA + +++L + E +K + L+ Q+F D +E +W+ E+EL +M +KD+Q +++K Q LE +++Y I + S + P+ + ++ V+ + LK + E++ + + ++E WI ER +A S + G+D + T+LRD+F F+ +T+ IG +V+ N + DELI+ HP S++ WKD +NE WADLLEL+DTR Q+L ++++LHR++ D++ L ++EKK ++ +LG+D +V L R+ +E D+ L + + L Y +K + + + + +A+ L + R+L L+ + F +MVR+L+ W++ + +Q++ PRDVS L++ANH+ +K E++++ +F+ C ++G +LL H S EI+ K +++ KRD + QKW + +DHL +++EV Q+ RDA+ AE+W+ QE + LG +DE +L+K+ F+K E++F L++LTT+E EHE IQ + E + P E Q ++ +SLDQ + + G ++ QS+ P P+ LS PVP + +Q RP+ + S+ V+ + + +AS P + P M+G L RKH+ E+ +KA+NR+W ++Y +L + + F+KD + P Y E+P+ L E A DY KR VF++R +G E+LFQ +M+ W+ +I+S+ M P + +P Q + + ++PP
Sbjct: 27 LAAEAEWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLGRVTCRIGDLYTDLRDGRMLIRLLEVLSGEQLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRSDLIEFDTLKRSNAHYNLQNAFNVAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDYAIEADQLIEKYETLASELLQWIEQTIVTLNDRQLANSLSAVQNQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEMLAARFDRKAAMRETWLSENQRLVSQDNFGFDLGAVEAATRKHEAIETDIGAYGERVAAVESVARELEAEAYHEVRRILARKDNVLRLWEYLKELLTARRERLTTHRDLQRLLEEMRYIMDWMGDMKGRLQSQDSGKHLHDVEDLLQKHTLVEADISAQAERVRGVQAAAKRFT--TDE---MPYKPCEPALVEEKVSLLGKTYDELGHLAGERRVKLEDSRRLWQFLWELGEEAAWIREQEQILSSGDSGRDLSSALHLLSKHEAFRDEMAARYGPLSNSIASGEQLVQEGHFGAPEVTERIKDIRAQWSHLEEASKLREQLLKESVALHQFQTDANDMEAWILETLRQVSSQEVGHDEFSTQTLARKQREVEEEIQSHRSLIDSLHEQAETLPA-AYAQSPEVEGRLPAIEQRYEELETLSSARRQALEGALALYRMFSEAGACQLWIGEKEQWLHNMEIPS-KLEDLEVVQQRFETLEPEMNNLGSRITDVNQVSEQLLKSDNRNKEQINQTQDQLNNRWSEFKRVADERKQALESALNIQNYHLECNEIQSWMKEKTKVIESTQSLGNDLAGVMALQRKLTGMERDLEAIQGKLGGLRSEAEKLASEHPEQAGEIRARLEEIQEVWEELRSTMKRREESLGEASKLQGFLRDLDDFQAWLSRTQTAVASEDTPTSLAEAERLLAQHEAIKNEVDNYREDYEKMRATGAEVTQGQTDA-QYMFLAQRLQALDTGWHELRRMWESRHCLLAQAFDFQTFLRDAKQAEGFLNSQEYVL---------SHTEMPNSLQGAVEAIKKHEDFLTTMEASEEKINGVVESGRRLVSDGNANADKIQEKADSIQERHQKNKQTANDLLTKLKDNRELQHFLQDGQELTLWINEKMLTAQDMSYDEARNLHSKWQKHQAFMAELASNKDWLDKIDKEGQALVVEKPELEETVSETLQGLQKQWEELENTTQTKAQCLFDANRAELFTQSCSALDSWLQNISSLLQSDD----FGKDLTSVNILLKK---HQMLEHQMEVREKEVQSLQSQALALAQED--AGVMEVDGQQRRVADSFT-QLQEPLNQRRQQLLASKEAHQFNRDLEDEILWVKERMPLATSTDHGKDLPSVQLLIK------KNQTLQKEIQGHQPRIDDIQAHGRSMDGE---RRADLDGRLSELGEEWSRFISETDKRHSRLAEANRAQQFYTDAAEAEAWMGEQELHMMS-EEKAKDEQSALVMVKKHQILEQALEDYAQTIHQLANSSRLMVNSEHPESERITLRQAQVDKLYAGLKDLAEERRGRLQERLRLTQLKREVDDLEQWIAEREVVAGSHELGQDYEHVTMLRDKFREFARDTSAIGQERVDAVNAQADELIESGHPENASVAEWKDGLNEAWADLLELMDTRTQMLAASYELHRFHQDAREALGRVKEKKEAL-AGAELGRDLNTVQHLHRQHTAYEHDVHALSGQVTQVQDDAARLQKAYAGEKAEDIHRHERAVTEAWEGLLAATQSRRLLLLDTVEKFRFFNMVRDLMLWMDGINLQIQSHDSPRDVSSAGLVIANHQDIKAEIETRAGSFTACTDMGNSLLNNNHYASDEIREKLEQLKAKRDEIKQKWQDKMDHLQIVLEVLQFGRDASVAESWLAGQEPLVRAAELGSNVDEVESLIKRHEAFEKLAAGWEDRFVLLEKLTTLE------------------------EHE----IQRLKEEEERARRPPTPPPAEEVVQSEAEHESAARTSLDQTTLNQSVSVNGVHSDQDTSQSLSVSVSELPNPEPKPLSKPVSKPVPKPYKAQQRYRPEKGSESESVNGPGRDSGLDTASRHDPSATLPGRVDPSTEAMEGMLCRKHEMESHAKKAANRSWQNVYCVLRKGSLGFYKDNKSASNGIP---YHGEVPISLNEATCEVAHDYKKRKNVFKLRLGDGKEFLFQAKDEAEMSSWIRSIHSS---MPSSGPGDRSPG-GQRGLSRAMTMPP 2354
BLAST of Spectrin beta chain vs. Ensembl Cavefish
Match: sptbn2 (spectrin beta chain, non-erythrocytic 1-like [Source:NCBI gene;Acc:103032213]) HSP 1 Score: 1304.27 bits (3374), Expect = 0.000e+0 Identity = 811/2398 (33.82%), Postives = 1337/2398 (55.75%), Query Frame = 1
Query: 154 LSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNF-IPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXD-HSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKII----AEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDS---EIKDTGYFQKVNSRQSMM-----RPFPQSSALS-----PVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSAS---PKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEK-PKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPP 7251
L+ E E N ++++FERSRIKALADERE VQKKTFTKW+NS L VT +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VN+ NFT SWR GL F A++HKHR DLI+F + R++ NL AF++AE LG+ LLDPEDVNV PDE+S+ITYVA+YYHYF+ +KA +V KR+ K+L+ +E +Q+I+ Y++L S+LL+WI TI LN RQ +NS+ +Q Q+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KAA+RE+W+++N L+ + + G +L V AA +KHEAIETDI AY E + + ++ LE E Y+++ I+ K+ VL LW+ L + L RRE L + + L+ E + + + + + + GKHL +VE+LL+ H L+E+DI + +R+ + + A R+ D+ A+++EK + K + EL +R+ L+ S +WQF+ + E WI+E I+++ D G DLSS LL KH+ F E++++ L N + G+ LV G + + DI+ W L ++++ R+ L E + +Q+ +D +D E WI E R + +G T+ L RK ++ E ++++R I+ + QA++L + V +L IE++Y++L ++ ++ L AL +YR+ +++ + + WI EK+++L N IPS +E+LEV++ RFE E E+ ++ VN +SE L+ + N N + I QD LNN W++ + D ++ L S + N+ ++C + W++EK K+IES LG DL VM QR++ M+RD+ AI+ K+ L ++ +++ + A +I +L+ + + WE L+ ++ R+ +L + + F++ LDDF WL + QT +AS++ P S +EAE+L+ ++ + ++E+ + E+ G + + + D Q++ L R+++++ W L + E + L + F DA+Q E LN+QE L + ++L E + ++E F+ M + E+ + V++ G+ L+ + N D++Q K ++ ER +KN A + KLK+ L LQD +L + EK+ ++S ++ S + +A E+ + + +++++K G+ + P ++ + + L L W EL + K Q L NR +LF +S ++ WL+NI + +DD +TS+ LKK H M + + ++ S+ L D + +++ Q + D + L+ L+ Q+++ A QF +D +DEI W+ E++ L + K + ++ L++ ++++++ EI+ ++D + + M E +RA + +++L + E +K + L+ Q+F D +E +W+ E+EL +M +KD+Q +++K Q LE +++Y I + S + P+ + ++ V+ + LK + E++ + + ++E WI ER +A S + G+D + T+LRD+F F+ +T+ IG +V+ N + DELI+ HP S++ WKD +NE WADLLEL+DTR Q+L ++++LHR++ D++ L ++EKK ++ +LG+D +V L R+ +E D+ L + + L Y +K + + + + +A+ L + R+L L+ + F +MVR+L+ W++ + +Q++ PRDVS L++ANH+ +K E++++ +F+ C ++G +LL H S EI+ K +++ KRD + QKW + +DHL +++EV Q+ RDA+ AE+W+ QE + LG +DE +L+K+ F+K E++F L++LTT+E EHE IQ + E + P E Q ++ +SLDQ + + G ++ QS+ P P+ LS PVP K K Q + S+ V+ + + +AS P + P M+G L RKH+ E+ +KA+NR+W ++Y +L + + F+KD + P Y E+P+ L E A DY KR VF++R +G E+LFQ +M+ W+ +I+S+ M P + +P Q + + ++PP
Sbjct: 27 LAAEAEWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLGRVTCRIGDLYTDLRDGRMLIRLLEVLSGEQLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRSDLIEFDTLKRSNAHYNLQNAFNVAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDYAIEADQLIEKYETLASELLQWIEQTIVTLNDRQLANSLSAVQNQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEMLAARFDRKAAMRETWLSENQRLVSQDNFGFDLGAVEAATRKHEAIETDIGAYGERVAAVESVARELEAEAYHEVRRILARKDNVLRLWEYLKELLTARRERLTTHRDLQRLLEEMRYIMDWMGDMKGRLQSQDSGKHLHDVEDLLQKHTLVEADISAQAERVRGVQAAAKRFT--TDE---MPYKPCEPALVEEKVSLLGKTYDELGHLAGERRVKLEDSRRLWQFLWELGEEAAWIREQEQILSSGDSGRDLSSALHLLSKHEAFRDEMAARYGPLSNSIASGEQLVQEGHFGAPEVTERIKDIRAQWSHLEEASKLREQLLKESVALHQFQTDANDMEAWILETLRQVSSQEVGHDEFSTQTLARKQREVEEEIQSHRSLIDSLHEQAETLPA-AYAQSPEVEGRLPAIEQRYEELETLSSARRQALEGALALYRMFSEAGACQLWIGEKEQWLHNMEIPS-KLEDLEVVQQRFETLEPEMNNLGSRITDVNQVSEQLLKSDNRNKEQINQTQDQLNNRWSEFKRVADERKQALESALNIQNYHLECNEIQSWMKEKTKVIESTQSLGNDLAGVMALQRKLTGMERDLEAIQGKLGGLRSEAEKLASEHPEQAGEIRARLEEIQEVWEELRSTMKRREESLGEASKLQGFLRDLDDFQAWLSRTQTAVASEDTPTSLAEAERLLAQHEAIKNEVDNYREDYEKMRATGAEVTQGQTDA-QYMFLAQRLQALDTGWHELRRMWESRHCLLAQAFDFQTFLRDAKQAEGFLNSQEYVL---------SHTEMPNSLQGAVEAIKKHEDFLTTMEASEEKINGVVESGRRLVSDGNANADKIQEKADSIQERHQKNKQTANDLLTKLKDNRELQHFLQDGQELTLWINEKMLTAQDMSYDEARNLHSKWQKHQAFMAELASNKDWLDKIDKEGQALVVEKPELEETVSETLQGLQKQWEELENTTQTKAQCLFDANRAELFTQSCSALDSWLQNISSLLQSDD----FGKDLTSVNILLKK---HQMLEHQMEVREKEVQSLQSQALALAQED--AGVMEVDGQQRRVADSFT-QLQEPLNQRRQQLLASKEAHQFNRDLEDEILWVKERMPLATSTDHGKDLPSVQLLIK------KNQTLQKEIQGHQPRIDDIQAHGRSMDGE---RRADLDGRLSELGEEWSRFISETDKRHSRLAEANRAQQFYTDAAEAEAWMGEQELHMMS-EEKAKDEQSALVMVKKHQILEQALEDYAQTIHQLANSSRLMVNSEHPESERITLRQAQVDKLYAGLKDLAEERRGRLQERLRLTQLKREVDDLEQWIAEREVVAGSHELGQDYEHVTMLRDKFREFARDTSAIGQERVDAVNAQADELIESGHPENASVAEWKDGLNEAWADLLELMDTRTQMLAASYELHRFHQDAREALGRVKEKKEAL-AGAELGRDLNTVQHLHRQHTAYEHDVHALSGQVTQVQDDAARLQKAYAGEKAEDIHRHERAVTEAWEGLLAATQSRRLLLLDTVEKFRFFNMVRDLMLWMDGINLQIQSHDSPRDVSSAGLVIANHQDIKAEIETRAGSFTACTDMGNSLLNNNHYASDEIREKLEQLKAKRDEIKQKWQDKMDHLQIVLEVLQFGRDASVAESWLAGQEPLVRAAELGSNVDEVESLIKRHEAFEKLAAGWEDRFVLLEKLTTLE------------------------EHE----IQRLKEEEERARRPPTPPPAEEVVQSEAEHESAARTSLDQTTLNQSVSVNGVHSDQDTSQSLSVSVSELPNPEPKPLSKPVSKPVP--KPYKAQQRGSESESVNGPGRDSGLDTASRHDPSATLPGRVDPSTEAMEGMLCRKHEMESHAKKAANRSWQNVYCVLRKGSLGFYKDNKSASNGIP---YHGEVPISLNEATCEVAHDYKKRKNVFKLRLGDGKEFLFQAKDEAEMSSWIRSIHSS---MPSSGPGDRSPG-GQRGLSRAMTMPP 2349
BLAST of Spectrin beta chain vs. Ensembl Cavefish
Match: SPTBN1 (spectrin beta, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11275]) HSP 1 Score: 1296.57 bits (3354), Expect = 0.000e+0 Identity = 765/2091 (36.59%), Postives = 1239/2091 (59.25%), Query Frame = 1
Query: 184 NVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDK---ASKYEQLETQVKVTMDGLSVPLESK--LSIANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PD-EYKGIVKD-VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEI 6396
N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY+DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + +SAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+SVITYV +YYHYF+ +KA V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +L V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ VL LW+ LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R+ + S A ++ D D + +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D+G DL+ RLL +H+ E E+S + L++ + EG + D G+ I + ++Q W AL RK +L E +Q+ +D DD + W + R+ +G T+ L++ ++ V +YR I+ + Q+++ L + + V+ +L IE++Y+++ ++ ++ L DAL +Y++ +++D+ WI EK+++L + + +E+LEV++HRFE E E+ +A +V VN ++ L+ +G+P+ + I QD LN W++ D+VD K++ L S N+ +DC +T WIREK K+IES ELG DL VM QR++ M+RD+ AIEAK+ L + + + + AK I +L + WE ++ +R+R+++L + + +F+++LDDF +WL + QT +AS+++P + +EAEKL+ ++ ++E+ E+ ++ +G+ + + D Q++ L+ R+++++ W L+ + E ++ L + +F D +Q E LN QE L + L + + E F+ M ++E+ + V++ G+ L + N+ DR+Q + ++DER KKN AA +LK+ L + LQD +L EK+ ++S ++ S + +A E+ + + ++++ K G Q A+ P + + + L L W EL + K Q L N+ +LF +S + KWL +EGQI +DD +TS+ LKK ++E +K+ +E L+ + +L+Q+ D + E +E + + +D PL + +A+++I QF +D +DEI W+ E++ + + ++T+ L++ ++++++ EI+ + D + + +Q ++ E+ + ++ L+ + + +E EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ L P+ E G+ + V+ + LK + E++ ++ + + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N+ DELI H A +++ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ +L I +K + +LG+D +V LQR FE D+ L + + + L Y DK + ++ E++DA+R+L + E R+ L+ D F SMVR+L+ W+E+V +E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG++LL KH S EIK K ++TDKR + KW + + L L++EV+Q++RDA AEAW++ QE YL++ +G ++D+ L+K+ F+K+ EE+F L+RLTTME+
Sbjct: 33 NSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYMDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKRSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSVITYVVTYYHYFSKMKALKVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLQAVEAATKKHEAIETDIAAYEERVQAVVSVARELEAENYHDIKRITARKDNVLRLWEYLLELLKARRQRLEMNLGLQRVFQEMLYIMDWMDEMKMLLLSQDYGKHLLGVEDLLQKHALVEADIGIQADRVRNVNSNAQKFA--IDDD---GYKPCDPQVIRDRVAHLEFCYQELTQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEQILSSDDVGKDLTGAVRLLSQHRALEDEMSGRGGHLQHTVREGLAMADAGHFGETRIRERVAEVQAQWAALEQLAAVRKARLEEACGLHQFQADADDVDAWTLDALRIVSSGDVGHDEFSTQALVKTHKDAAAEVASYRPVIDALHEQSRA-LPPELAESADVSGRLAGIEERYKEVAELTRLRKQALQDALALYKMFSEADACEVWIVEKEQWLNSMEIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSEKDIKAQQDKLNTRWSQFRDLVDQKKESLNSALGVQNYHLDCNETKSWIREKTKVIESTQELGNDLTGVMALQRKLTGMERDLAAIEAKLGDLKGEAERLAGEHPEQAKAITGRLAEIDSVWEEMKDTLRNREASLGEASKLQQFLRELDDFQSWLSRTQTAIASEDMPNTLAEAEKLLAQHEGIKNEIHNYEEDYQKMRDMGEMVTQGQTDA-QYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQLFLRDTKQAEAFLNNQEYVLA---------HTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINSVVEAGRRLASDGNINTDRIQERAASIDERHKKNREAAVELLMRLKDNRDLQKFLQDCQELSLWTNEKMLTAQDMSYDEARNLHSKWLKHQAFMAELQSNKEWLDKIEKEGMQLVAEKPETEAIVKEKLSALQKQWQELESTTQTKAQCLFDANKAELFTQSCADLDKWLGGLEGQIQSDDYG----KDLTSVNILLKKQQMLENQVEVRKREVEELQSQAHVLRQEGKDTDEVDGRREVVEKKFQEMLD----PLMKRKNFLMASREI--HQFNRDVEDEILWVEERMPIATSTDHGHNLQTVQLLIK------KNQTLQKEIQGHQPRCDDIFERSQSILKEDSPSVEAIKARLSDLQTLWDLIIQETEKRHERLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSSVTMLKKHQILEQAVEDYAETVHQLSKTSRGLVAANHPESERIGMRQSQVDKLYAGLKDLSEERRGKLD------ERFRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDSVNRMADELINAGHTDAATVAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEILSRILDKHKMLP--EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAVRLQSAYAGDKADDIQRRETEVLDAWRNLLEACEGRRARLLDTGDKFRFFSMVRDLMLWMEDVIRLIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKSLLARKHYASEEIKDKLLQLTDKRKEMIDKWEDRWEWLRLILEVHQFSRDAGVAEAWLLGQEPYLSSREMGQSVDDVEKLIKRHEAFEKSAATWEERFSALERLTTMEL 2082 HSP 2 Score: 123.635 bits (309), Expect = 2.202e-27 Identity = 130/636 (20.44%), Postives = 275/636 (43.24%), Query Frame = 1
Query: 4612 QFLQDCDDEIDWMNEKIDLIRNR--SKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINS---KDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPDE------YKGIVKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTK-HIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQ-WARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNT----DRQFINEALINIEQTAE 6468
+F + +E W+ EK ++ + K + LL +H+++++E+ R + ++E M D H + + V +++ L + + L + +F D +V +W LD + +V + D+ + +++ ++ E+ +Y P I+ + +LP E G + +E+ + + + +K + + + E WIVE+ + S + + L+ +++ RF E N +S+V N+ +L+ HP I +D++N W+ +L+D + + L SA + ++ D I+EK +E +LG D V LQRKL E+DL +++ + + + L + + +A + + E+ + ++ L +R+ + E + FL + + W+ + P ++ E LLA H +K E+ + EE++ ++G + + + + ++ + + + + L + W N + LS YQ + RD AEA++ +QE L + + TL+ A +KK +E F +TTM+ +K+N+ R+ ++ IN ++ E
Sbjct: 641 KFFWEMAEEEGWIREKEQILSSDDVGKDLTGAVRLLS------QHRALEDEMSGRGGHLQHTVREGLAMADAGHFGETRIRERVAEVQAQWAALEQLAAVRKARLEEACGLHQFQADADDVDAWT----LDALRIVSSGDVGHDEFSTQALVKTHKDAAAEVASYRPVIDALHEQSRALPPELAESADVSGRLAGIEERYKEVAELTRLRKQALQDALALYKMFSEADACEVWIVEKEQWLNSMEIPEKLEDLEVIQHRFESLEPEMNN-QASRVAVVNQIARQLMHSGHPSEKDIKAQQDKLNTRWSQFRDLVDQKKESLNSALGVQNYHLDCNETKSWIREKTKVIESTQELGNDLTGVMALQRKLTGMERDLAAIEAKLGDLKGEAERLAGEHPEQAKA-ITGRLAEIDSVWEEMKDTLRNREASLGEASKLQQFLRELDDFQSWLSRTQTAIASEDMPNTLAEAEKLLAQHEGIKNEIHNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLS-QSHAYQLFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKK-----------QEDF-----MTTMDANEEKINSVVEAGRRLASDGNINTDRIQE 1247
BLAST of Spectrin beta chain vs. Ensembl Cavefish
Match: sptbn2 (spectrin beta chain, non-erythrocytic 1-like [Source:NCBI gene;Acc:103032213]) HSP 1 Score: 1292.33 bits (3343), Expect = 0.000e+0 Identity = 801/2382 (33.63%), Postives = 1326/2382 (55.67%), Query Frame = 1
Query: 154 LSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNF-IPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXD-HSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKII----AEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEK-PKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPP 7251
L+ E E N ++++FERSRIKALADERE VQKKTFTKW+NS L VT +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VN+ NFT SWR GL F A++HKHR DLI+F + R++ NL AF++AE LG+ LLDPEDVNV PDE+S+ITYVA+YYHYF+ +KA +V KR+ K+L+ +E +Q+I+ Y++L S+LL+WI TI LN RQ +NS+ +Q Q+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KAA+RE+W+++N L+ + + G +L V AA +KHEAIETDI AY E + + ++ LE E Y+++ I+ K+ VL LW+ L + L RRE L + + L+ E + + + + + + GKHL +VE+LL+ H L+E+DI + +R+ + + A R+ D+ A+++EK + K + EL +R+ L+ S +WQF+ + E WI+E I+++ D G DLSS LL KH+ F E++++ L N + G+ LV G + + DI+ W L ++++ R+ L E + +Q+ +D +D E WI E R + +G T+ L RK ++ E ++++R I+ + QA++L + V +L IE++Y++L ++ ++ L AL +YR+ +++ + + WI EK+++L N IPS +E+LEV++ RFE E E+ ++ VN +SE L+ + N N + I QD LNN W++ + D ++ L S + N+ ++C + W++EK K+IES LG DL VM QR++ M+RD+ AI+ K+ L ++ +++ + A +I +L+ + + WE L+ ++ R+ +L + + F++ LDDF WL + QT +AS++ P S +EAE+L+ ++ + ++E+ + E+ G + + + D Q++ L R+++++ W L + E + L + F DA+Q E LN+QE L + ++L E + ++E F+ M + E+ + V++ G+ L+ + N D++Q K ++ ER +KN A + KLK+ L LQD +L + EK+ ++S ++ S + +A E+ + + +++++K G+ + P ++ + + L L W EL + K Q L NR +LF +S ++ WL+NI + +DD +TS+ LKK H M + + ++ S+ L D + +++ Q + D + L+ L+ Q+++ A QF +D +DEI W+ E++ L + K + ++ L++ ++++++ EI+ ++D + + M E +RA + +++L + E +K + L+ Q+F D +E +W+ E+EL +M +KD+Q +++K Q LE +++Y I + S + P+ + ++ V+ + LK + E++ + + ++E WI ER +A S + G+D + T+LRD+F F+ +T+ IG +V+ N + DELI+ HP S++ WKD +NE WADLLEL+DTR Q+L ++++LHR++ D++ L ++EKK ++ +LG+D +V L R+ +E D+ L + + L Y +K + + + + +A+ L + R+L L+ + F +MVR+L+ W++ + +Q++ PRDVS L++ANH+ +K E++++ +F+ C ++G +LL H S EI+ K +++ KRD + QKW + +DHL +++EV Q+ RDA+ AE+W+ QE + LG +DE +L+K+ F+K E++F L++LTT+E EHE IQ + E + P E Q ++ +SLDQ + + + V+S Q Q + K + +++ P + + T P + P M+G L RKH+ E+ +KA+NR+W ++Y +L + + F+KD + P Y E+P+ L E A DY KR VF++R +G E+LFQ +M+ W+ +I+S+ M P + +P Q + + ++PP
Sbjct: 27 LAAEAEWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLGRVTCRIGDLYTDLRDGRMLIRLLEVLSGEQLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRSDLIEFDTLKRSNAHYNLQNAFNVAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDYAIEADQLIEKYETLASELLQWIEQTIVTLNDRQLANSLSAVQNQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEMLAARFDRKAAMRETWLSENQRLVSQDNFGFDLGAVEAATRKHEAIETDIGAYGERVAAVESVARELEAEAYHEVRRILARKDNVLRLWEYLKELLTARRERLTTHRDLQRLLEEMRYIMDWMGDMKGRLQSQDSGKHLHDVEDLLQKHTLVEADISAQAERVRGVQAAAKRFT--TDE---MPYKPCEPALVEEKVSLLGKTYDELGHLAGERRVKLEDSRRLWQFLWELGEEAAWIREQEQILSSGDSGRDLSSALHLLSKHEAFRDEMAARYGPLSNSIASGEQLVQEGHFGAPEVTERIKDIRAQWSHLEEASKLREQLLKESVALHQFQTDANDMEAWILETLRQVSSQEVGHDEFSTQTLARKQREVEEEIQSHRSLIDSLHEQAETLPA-AYAQSPEVEGRLPAIEQRYEELETLSSARRQALEGALALYRMFSEAGACQLWIGEKEQWLHNMEIPS-KLEDLEVVQQRFETLEPEMNNLGSRITDVNQVSEQLLKSDNRNKEQINQTQDQLNNRWSEFKRVADERKQALESALNIQNYHLECNEIQSWMKEKTKVIESTQSLGNDLAGVMALQRKLTGMERDLEAIQGKLGGLRSEAEKLASEHPEQAGEIRARLEEIQEVWEELRSTMKRREESLGEASKLQGFLRDLDDFQAWLSRTQTAVASEDTPTSLAEAERLLAQHEAIKNEVDNYREDYEKMRATGAEVTQGQTDA-QYMFLAQRLQALDTGWHELRRMWESRHCLLAQAFDFQTFLRDAKQAEGFLNSQEYVL---------SHTEMPNSLQGAVEAIKKHEDFLTTMEASEEKINGVVESGRRLVSDGNANADKIQEKADSIQERHQKNKQTANDLLTKLKDNRELQHFLQDGQELTLWINEKMLTAQDMSYDEARNLHSKWQKHQAFMAELASNKDWLDKIDKEGQALVVEKPELEETVSETLQGLQKQWEELENTTQTKAQCLFDANRAELFTQSCSALDSWLQNISSLLQSDD----FGKDLTSVNILLKK---HQMLEHQMEVREKEVQSLQSQALALAQED--AGVMEVDGQQRRVADSFT-QLQEPLNQRRQQLLASKEAHQFNRDLEDEILWVKERMPLATSTDHGKDLPSVQLLIK------KNQTLQKEIQGHQPRIDDIQAHGRSMDGE---RRADLDGRLSELGEEWSRFISETDKRHSRLAEANRAQQFYTDAAEAEAWMGEQELHMMS-EEKAKDEQSALVMVKKHQILEQALEDYAQTIHQLANSSRLMVNSEHPESERITLRQAQVDKLYAGLKDLAEERRGRLQERLRLTQLKREVDDLEQWIAEREVVAGSHELGQDYEHVTMLRDKFREFARDTSAIGQERVDAVNAQADELIESGHPENASVAEWKDGLNEAWADLLELMDTRTQMLAASYELHRFHQDAREALGRVKEKKEAL-AGAELGRDLNTVQHLHRQHTAYEHDVHALSGQVTQVQDDAARLQKAYAGEKAEDIHRHERAVTEAWEGLLAATQSRRLLLLDTVEKFRFFNMVRDLMLWMDGINLQIQSHDSPRDVSSAGLVIANHQDIKAEIETRAGSFTACTDMGNSLLNNNHYASDEIREKLEQLKAKRDEIKQKWQDKMDHLQIVLEVLQFGRDASVAESWLAGQEPLVRAAELGSNVDEVESLIKRHEAFEKLAAGWEDRFVLLEKLTTLE------------------------EHE----IQRLKEEEERARRPPTPPPAEEVVQSEAEHESAARTSLDQTT-LNQSVSVNGVHSDQD-------------TSQYRPEKGSESESVNGPGRDSGLDT-ASRHDPSATLPGRVDPSTEAMEGMLCRKHEMESHAKKAANRSWQNVYCVLRKGSLGFYKDNKSASNGIP---YHGEVPISLNEATCEVAHDYKKRKNVFKLRLGDGKEFLFQAKDEAEMSSWIRSIHSS---MPSSGPGDRSPG-GQRGLSRAMTMPP 2320
BLAST of Spectrin beta chain vs. Ensembl Cavefish
Match: ENSAMXT00000030945.1 (spectrin beta chain, non-erythrocytic 1-like [Source:NCBI gene;Acc:103033421]) HSP 1 Score: 1290.79 bits (3339), Expect = 0.000e+0 Identity = 768/2101 (36.55%), Postives = 1243/2101 (59.16%), Query Frame = 1
Query: 130 LSSDYQNALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNE-IVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLS--IANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEI 6396
+SD N D DE N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY+DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +L V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ VL LW LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R++ + S A ++ D + +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ D G DL++V RLL KHK E E S + L+ + +G+ LV G + I + +D+Q W +L +R+ +L + +Q+ +D DD + W+ + R+ +G + L++K++ E + +YR ++ + QA++L + V+ +L IE++Y+++ ++ ++ L DAL +Y++L+++D+ WI EK+++L + + +E+LEV++HRF+ E E+ +A +V VN ++ L+ +G+P+ + I QD LN W++ D+VD K++ L S N++++C +T WIREK K+IES +LG DL VM QR++ M+RD+ AIE K+ L + D + + A I+ +L + WE ++ +R R+ +L + + +F+++LDDF WL + QT +AS++ P + +EAEKL+ ++ ++E+ E+ ++ +G+ + + D Q + L+ R+++++ W L + E ++K L + +F D +Q E LN QE L +T ++ L E + + E F+ M ++E+ + V++ G+ L+ + N+ +R+Q K ++DER KKN AA KLK+ L LQD +L + EK+ ++S ++ S + +A E+ + + ++++ K G + P + + ++ L TW EL + K Q L N+ +LF +S + KWL +EGQI +DD +TS+ LKK ++E ++K +E L+ ++ L Q+ + + + V+V + PL+ + S +A+++I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ + D + + + R + E A + + L++ + + EE+EK L Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + K+ +L P+ + ++ V+ + LK + E++ ++ ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ NK D+LI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ +L I +K + ++LG+D +V LQR FE D+ L + + + L Y DK + ++ E+++A+RSL + + R++ L+ +D F SMVR+L+ W+E+V ++ + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG+ LL KH S EIK K ++TDKR + KW + + L L++EV+Q++RDA AEAW++ QE YL++ +G +DE L+K+ F+K+ EE+F L+RLTTME+
Sbjct: 17 FTSDVNNRW-DADEWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYMDLRDGRMLIKLLEVLSGEKLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVEHPDEKSIITYVVTYYHYFSKMKALKVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRTELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLQAVEAATKKHEAIETDIAAYEERVQVVVAVAGELEAENYHDIKRITARKDNVLRLWDYLLELLRARRQRLELNLGLQRVFQEMLYIMDWMDEMKMLLLSQDYGKHLLGVEDLLQKHALVEADIAIQADRVKSVNSNAQKFA-----DDSEGYKPCDPQVIRDRVAHMEFCYQELTQLAAERRGRLEESRRLWKFFWEMAEEEGWIREKEQILSSEDCGKDLTAVVRLLSKHKALEDERSGRAGRLQQTVQQGEELVAAGHFGADKIRQRISDVQEQWASLERLFSARRTRLQDACALHQFQADADDMDAWMLDVLRIVSSADVGHDEFSAQSLVKKHKDVAEEISSYRPVLDALHEQARTLPEEQARAGE-VSGRLAGIEERYKEVAELTRLRKQALQDALALYKMLSEADACELWIVEKEQWLNSMEIPEKLEDLEVIQHRFDSLEPEMNSQASRVAVVNQIARQLIHSGHPSEKEIKGQQDKLNTRWSQFRDLVDRKKEALNSTLGVQNYYLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEDKLGDLGKEADRLSEEHGDKASGIKGRLGEIKDVWEEMKGTLRTREESLGEASKLQQFLRELDDFQAWLSRTQTAVASEDKPNTLAEAEKLLAQHEGIKNEIRNYEEDYQKMRDMGEMVTQGQTDA-QHMFLRQRLQALDTGWNELQKMWENRQKLLSQSHAYQLFLRDTKQAEAFLNNQEYVLA----------HTEMADTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNISAERIQEKVDSIDERRKKNRGAASELLTKLKDNRDLQRFLQDCQELSLWISEKMLTAKDMSYDEARNLHSKWLKHQAFMAELQSNKEWLDKIQKAGSALVEEKPETEAVVQGKMEMLKKTWEELESTTQTKAQCLFDANKAELFTQSCADLDKWLSGLEGQIHSDD----FGKDLTSVNILLKKQQMLESQVEVRQKEVEELRSQAQALSQEGKG-SDEVDGRRRGVEVKFQQVQEPLKKRRSNLMASREI--HQFNRDVEDEILWVEERMALATSTDHGNNLQTVQLLIK------KNQTLQKEIQGHQPRYDDIFERSVRTLQEESPVSAGIRLRLEDLQRIWKLIQEEVEKRHGRLEEAHRAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSSVAMLKKHQILEQAVEDYAETVHQLSKTSRALVAAGHPESERISMRQSQVDKLYAGLKDLSEERRGKLDERSRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDAVNKMADDLINSGHADAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEVLGRILDKHKKLP--DELGRDQNTVETLQRMHTTFEHDIQALGTQVKQLQEDAVRLQSAYAGDKADDIQRREGEVLEAWRSLLEACDGRRVRLLDTSDKFRFFSMVRDLMLWMEDVIRLIDAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKALLARKHYASEEIKEKLLQLTDKRKEMIDKWEDRWEWLRLVLEVHQFSRDAGVAEAWLLGQEPYLSSREMGQNVDEVEKLIKRHEAFEKSAATWEERFSALERLTTMEL 2083
BLAST of Spectrin beta chain vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008111.1 (pep scaffold:Pmarinus_7.0:GL478136:8967:48859:1 gene:ENSPMAG00000007298.1 transcript:ENSPMAT00000008111.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 1320.45 bits (3416), Expect = 0.000e+0 Identity = 824/2418 (34.08%), Postives = 1377/2418 (56.95%), Query Frame = 1
Query: 184 NVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDI-------RSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLS--IANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PD-EYKGIVKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTT---MEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRF-NSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASN--RTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASR--------------PMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFSSIRLKK 7308
N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPTRG+MRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RL LGLIWTIILRFQ+QDI + + + +SAKDALLLWCQMKTAGY +VNI NFT SWR GL F A++HKHRPDLI+F +++ +NL AF+IAE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA +V KR+ K+L +E +QMI Y++L S+LLEWI TI +LN R+F+NS+ G+QQQ+ F+ YRT EKP+KF EK +LEVLLFTI+S + KVY P E ++ IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAALRE+W+++N L+ + + G +LP V AA KKHEAIE DI AYEE + + ++ LE E Y+++ + + ++ VL LW+ L + L RR L+ L + + E + + + + +YGKHL+ VE+LL+ H L+E+DI +++N ++ SE + Y + CD S++ S ++E+ + EL +R+ L+ S +W+F + + E W++E ++++ D+G DL+ V RLL +H+ E EL+ + L+ + EG+ + D G + I A+ ++ LW +L D RK +L YQ+ +D DD E W+++ R+ +G T+ L +K++ E + +YR ++ + QAQ L V V +L+ +E++Y++L++++ +++L DAL +Y++ +++++ WI EK ++L + +E+LEV++HRFE FE E+ +A ++ VN L+ L+ G+P+ Q I QD+LN+ W+ ++VD K++ L S NF ++C +T WIREK K+IES ELG DL VM QR+++ M+RD+ AI+ K+ L + + + + I +L ++Q W+ L++ +++R+ +L + + +F++ LDDF WL + QT +AS+++P + EAEKL+ ++ + ++E+ + + +G + + +Q Q++ L R+++++ W LN + E + L + F +DARQ + L+ QE Y++ ++ + L S E + +E + M ++++ + L+ G+ L+ E+N Y D++Q K ++DER KKN + A++ +LK+ L LQD +L + EK+ ++S ++ + + +A E+ + + +E++++ G+Q + P + + + L L+ W EL + K Q L NR +LF +S + KW+ IE QI +DD + +TS+ +KK ++E +KK +E L+ + +L Q+ + Q T V+ + + PL+ + +A++++ Q+++D +DEI W+ E++ L R+ ++T+ L++ ++++++ EI+ +++ + + + +I + + + + L+ + E + L L Q++ DV+E +W+SE+EL ++ +KD+Q +++K Q LE ++NY I + ++ +L P+ E G+ + D K+ K + ++L+Q ++E WI ER +A S + G+D + T+L +RF F+ +T IG +V+ N+ D LI+ H + S++ WKD +NE WADLLELIDTR Q+L ++++LHR+ D++ +L I EK+ M++ +LG+D +V LQRK FE D+ L + + L Y +K + ++ +E++ A++ L E RKL + + F S+VR+L+ W+E Q+ + KPRDVS +ELL+ NH+ +K E+D++ +NF+ + LG++LL +H + EIK K ++TDKR + KW L L++EV+Q+ARDA AEAW+++QE ++ + +G ++DE LLK+ F+K+ +E+F L++ TT +E+R ++ D + + L + E H I + Q + + + Q++ R+ N +D S++ + E + G +R+ P P S ++PQ +H+ SVST L + A+ +G L RKH+WE+ N+KAS+ R+WH+LY +L F+KD ++ Y +E+P+ L V A DY K+ V R++ +G +YL Q +M W+ +I +A+ PMR S T PS P ++ P + + K ++ FS +++KK
Sbjct: 37 NSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGEKLPKPTRGKMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLILGLIWTIILRFQIQDISVETEDNKERRSAKDALLLWCQMKTAGYQNVNIHNFTTSWRDGLAFNAIVHKHRPDLIEFDKLKKSNAHHNLQNAFNIAEQKLGLTKLLDPEDISVDQPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLESAIETDQMIDKYETLASELLEWIEQTIIILNNRKFANSLTGVQQQLQAFSTYRTVEKPNKFTEKGNLEVLLFTIQSKMRANNQKVYTPREGKLVNEINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAALRETWLSENQRLVTQDNFGVDLPAVEAATKKHEAIEADIAAYEERVQAVVDVARELEAEDYHEVRRVCSRRDNVLRLWEYLQELLAARRHRLEANLALQRVFQEMLHIVDWMDEMKVRLLSQDYGKHLLGVEDLLQKHALVEADITVQADRVKAVNAAAQRFSSEDDAY-KPCD----SHVVSERATHLEER-------YAELCSLAAERRSKLEESRKLWRFFWEMAELEGWVREKEPLLSSGDVGKDLTGVLRLLGQHRAVEDELNGRSADLKQTVREGEEMADAGHFGADDIRARVAEMHVLWASLEDLAAQRKRRLQVAESLYQFQADADDIEVWMEDTLRIVSSDEMGHDEFSTQSLNKKHKDVTEEISSYRPVLDALHEQAQGLPDEVTVS-AGVPDRLEALEQRYRELVELSRVRKQRLQDALALYKMYSEAEACELWIDEKSQWLNAMDVPEKLEDLEVIQHRFEGFEPEMNSQASRIAVVNQLARQLMHAGHPSEQDIKAKQDHLNSVWSDFRELVDQKKEALSSALSIQNFHLECNETKAWIREKTKVIESTQELGNDLAGVMALQRKLSGMERDLAAIQTKLADLQGEAERLASMHPEQEDAILGRLAEINQVWDNLKETLQNREESLGEASKLQQFLRDLDDFQTWLSKAQTAIASEDMPNTLPEAEKLLAQHEAIKNEIDNYQDDYQRMRDMG-EVVTRDQSDPQYMFLHQRLQALDTGWNELNKMWENRHSLLSQSHGFQAFLKDARQADGFLSNQE-YVLGHVE--------MPATLESAEEAIKNHEDVMTTMDTNDEKIVGALETGRRLLTEDNTYADKIQEKVDSIDERHKKNRMTAEDVLARLKDNRDLQRFLQDCQELTLWINEKMLTAQDMSYDEARNLHTKWQKHQAFMAELASNKEWLEKIDEEGQQLMVEKPETEPMVKEKLSELHELWDELENTTQLKAQRLFDANRAELFTQSCADLDKWVNQIESQISSDDHGN----DLTSVNILIKKQQMLENQMEVRKKEVEELQSQATVLCQEGKGRDEVDSQRLT-VENRFEQVLAPLQQRRDKLLASKEV--HQYIRDLEDEILWVEERMPLAASRDHGNNLQTVQLLIK------KNQNLQKEIQGHEPRIEDIRERGEDLIARGSVDPEAIHERLEDLRALWATMIVEAKDRHIRLEESLKAQQYYFDVAEAEAWMSEQELYMIA-DEKAKDEQSAVAMLKKHQILEQSVENYSDVIHQLSETSRNLVTSRHPESERIGLRQSQAD-----KLYAGLKDLAEERRGRLEERHKLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLSERFAEFARDTATIGQERVDSVNRIADALIEAGHSDSASVADWKDGLNEAWADLLELIDTRTQMLAASYELHRFNHDAREVLSRINEKQ--MQLPEELGRDQNTVESLQRKHTTFENDIQALGVQVKVLQEDAERLRGSYAGEKVEDIERREEEVVTAWKGLLDACEARKLRLADTGEKFRFFSLVRDLMLWMENTIRQINAQEKPRDVSSVELLMNNHQGIKAEIDTRNDNFTTVIELGKSLLARQHYATDEIKEKLGQLTDKRKEMVSKWEERAHWLKLILEVHQFARDAGVAEAWLLAQEPHITTQEVGESVDEVEQLLKRHEAFEKSVSTWDERFNVLEKHTTLELLELRKQQEKEDEERKQQKLQAELDEKKREEHHIAEQ-----QRIQSQEVTQNGISSDQESPRQGSNMLDPSVNGNGENEADG------ARKLTPEPSPSSD----------RRKPQ------TLHSQSVST--LPGKAEEASA-------FRKEGFLLRKHEWESHNKKASSSVRSWHTLYCVLHNQEFGFYKDSKNM--NTGNTYHNEIPVNLANAVCDVASDYKKKKHVLRLKLPDGNDYLLQAKDDEEMANWIHSIKAAASSRDSSSPSSQGSQAPMR----SKTMPSG----PPSEATSPEKKE--KDREKRFSFLKMKK 2362
BLAST of Spectrin beta chain vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001834.1 (pep scaffold:Pmarinus_7.0:GL482425:158920:175005:1 gene:ENSPMAG00000001663.1 transcript:ENSPMAT00000001834.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 808.905 bits (2088), Expect = 0.000e+0 Identity = 440/1174 (37.48%), Postives = 698/1174 (59.45%), Query Frame = 1
Query: 385 PKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPE-DVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKF-LGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDER 3900
PKPTRG+MRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RL LGLIWTIILRFQ+QDI + S +SAKDALLLWCQMKTAGYP+VN+ NFT SWR GL F A+IHKHRPDL+DF +++ +NL AF+ AE LG+ LLDPE DV+V PDE+S+ITYV S+YHYF+ +KA +V KR+ K+L+ +E ++M++ Y+SL S+LLEWI TI LN R F NS+ G+QQQ++ F+ YRT EKP KF EK +LEVLLFTI+S + KVY P E ++ IN AW+ L AE+GRE ALR EL+RQEKL LA++F++KAA+RE+W+ +N L+ + + G +L V AA KKHEAIETD+ AYE + + ++ LE E Y+++ ++ ++ VL LW++L + L RR L+ L + +E A + + + GKHL+ VE+LL+ H L+E+D+ + R++ + + A R+ + D + + E+ + EL R+ L+ + + F+ +A E W++++ ++ + D G+DL++V RLL +H+ FE ELS +R L+ L G+ + + A++ ++ LW +L + R +L +Q +SD D E W + L +G+ T+ L RK++ +E +E YR I+ ++ QA +L S+ + V ++L R+E+ Y +L +A + +L DAL +Y + +++ + W+ EK ++L + +E+LEV++HRFE E E+ A +V VN L+ L+ + + + I QD LN W++ ++ +SK++ L ++ +F ++C +T WIREK +LIES LG DL VM QR+++ M+RD+ AIE K+ L + + + +H+ A + QL W L+ +R R+ +L + + +F+Q +DDF WL + Q +AS+++P + EAEKL+ ++ + ++E++ + ++G++ + + D Q V L+ R+++++ W L+ + + + L L F DARQ + +L+ QE Y + ++ + L S + ++E M ++++ + VL G+ L+ E N D++Q K ++ ER
Sbjct: 1 PKPTRGKMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLILGLIWTIILRFQIQDISVQTEDSKETRSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAVIHKHRPDLVDFEKLKKSNAQHNLQHAFNAAEQHLGVTKLLDPEADVSVDQPDEKSIITYVVSFYHYFSKMKALAVEGKRIGKVLDSAIEADRMVERYESLASELLEWIGRTITALNSRDFPNSLVGVQQQLHAFSSYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYTPREGKLVAEINRAWERLEKAEHGRELALRDELIRQEKLEQLARRFDRKAAMRETWLAENQRLVMQDNFGADLAAVEAATKKHEAIETDMAAYEGRVRAVEGVARELEAERYHEVARVVRRRDGVLQLWRRLQELLAARRTRLEMTLALQRAFHEMLYTGAWMDEMKLRLLSQECGKHLLGVEDLLQKHALVEADVAAQADRVKAVNAAALRFAEEVD-----GYRPCDPEVASERAGQLEASYAELCALCAARRARLEEARALHLFLWEAEEVEAWVRQVEPLLASEDAGHDLAAVLRLLARHRAFEDELSGRRAQLQQTLRLGEEEKREAERDAQAARARSAELDKLWASLELAASRRAERLRASEALHQLLSDSADVEAWARDASLLVAAGGDVGNDEFSTQALARKHRDVVEEIEGYR--IDSLQEQAAALPA-SLAEPAGVRERLRRLEEAYGELAALAAERGRRLQDALALYTIHSETAACLLWLDEKSQWLDALDIPEKLEDLEVVQHRFESLEPEMNGLASRVAVVNQLARQLLGSEHASEDDIKAKQDLLNARWSEFRELAESKKEALQAQLTLQSFQLECHETQAWIREKTRLIESTQGLGNDLAGVMALQRKLSGMERDLAAIEVKVGDLQGEAERLAQHHPERAGAVRGQLADTADVWGALRGTLRAREDSLGEASKLQKFLQDVDDFQAWLSKTQKAVASEDVPSTLPEAEKLLAQHEAIKNEISNYSEDHRRMREMGEEVTRDQSDP-QHVFLRQRLQALHTGWAELHSMWDNRRALLAACHAYLAFARDARQADGVLSNQE-YALSRVE--------MPATLQSAEAAIKKHEELTTSMEANDEKVGSVLDTGRKLVGEGNFNADKIQEKMDSISER 1156 HSP 2 Score: 99.7525 bits (247), Expect = 6.334e-21 Identity = 127/605 (20.99%), Postives = 255/605 (42.15%), Query Frame = 1
Query: 4723 QLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPD---EYKGI---VKDVEDNFNSLKIICAEK----KTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLEC------IQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPE---IKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKK----LNTDRQFINEALINIEQTAE 6468
+L RH++ ++E+ R ++ ++ + E +L K +L + L A+ + L D ++V +W + L + D+ + + RK +++ EI+ Y +I+ ++ +LP E G+ ++ +E+ + L + AE+ + ++L+ I+ +T W+ E+++ + D + L+ +++ RF E N + +S+V N+ +L+ +H I +D +N W++ EL +++ + L++ L F LEC I+EK +E LG D V LQRKL E+DL ++ + + + L + ++ + + + D + +LR L R+ + E + FL V + W+ + + P + E LLA H ++K E+ + E+ +G + R + P+ ++ + + + L W N L+ +ARDA A+ + +QE L+ + TL A +K K E+L T+ME +K L+T R+ + E N ++ E
Sbjct: 576 RLLARHRAFEDELSGRRAQLQQTLRLGEEEKREAERDAQAARARSAELDKLWASLELAASRRAERLRASEALHQLLSDSADVEAWARDASLLVAAGGDVGNDEFSTQALARKHRDVVEEIEGY--RIDSLQEQAAALPASLAEPAGVRERLRRLEEAYGELAALAAERGRRLQDALALYTIHSETAACL----LWLDEKSQWLDALDIPEKLEDLEVVQHRFESLEPEMNGL-ASRVAVVNQLARQLLGSEHASEDDIKAKQDLLNARWSEFRELAESKKEALQAQLTLQ------SFQLECHETQAWIREKTRLIESTQGLGNDLAGVMALQRKLSGMERDLAAIEVKVGD-LQGEAERLAQHHPERAGAVRGQLADTADVWGALRGTLRAREDSLGEASKLQKFLQDVDDFQAWLSKTQKAVASEDVPSTLPEAEKLLAQHEAIKNEISNYSEDHRRMREMGEEVTRDQS--DPQHVFLRQRLQALHTGWAELHSMWDNRRALLAACHAYLAFARDARQADGVLSNQEYALSRVEMPATLQSAEAAIK--------------KHEELT--TSMEANDEKVGSVLDTGRKLVGEGNFNADKIQE 1148 HSP 3 Score: 63.5438 bits (153), Expect = 6.643e-10 Identity = 136/710 (19.15%), Postives = 293/710 (41.27%), Query Frame = 1
Query: 2689 SWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIRE-KIKLIESMDELGEDL---ESVMQRQRRINH---MQRD-ICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLN-EIVNENEIF-IDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCK--ALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMD---GLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRS 4773
+W+ E Q+ + D+ +E + E E+++ +V V ++ L +V +D + W ++ +++ ++R L F + T W+ E K++L+ E G+ L E ++Q+ + Q D + A+ A + D + A + QL+ + E L L R + L +H F+ + ++ W+ Q++ +AS++ + +L+ ++ + DE++ QL++ +++G++ + + Q R R +++ W L + + +RL D+ +E A++ L+ + N S L + ++V E E + ID + L L + ++ + + L+E + + A R +L++ + L+ + + L EK Q L+ + + K D + Q + +LE E+N + +N+ +Q + +I D LN+ W+E + E K + L + F+ W++ I + +G+ ++ +KL +L + + +L+ +E L Q +P++A + Q+ T D L L ++ + ++FLQD DD W+++ + + + TL + ++L +H+++KNEI N S
Sbjct: 337 TWLAENQRLVMQDNFGADLAAVEAATKKHEAIETDMAAYEGRVRAVEGVARELEAERYHEVARVVRRRDGVLQLWRRLQELLAARRTRLEMTLALQRAFHEMLYTGAWMDEMKLRLLSQ--ECGKHLLGVEDLLQKHALVEADVAAQADRVKAVNAAALRFAEEVDGYRPCDPEVASERAGQLEASYAE---LCALCAARRARLEEARALHLFLWEAEEVEAWVRQVEPLLASEDAGHDLAAVLRLLARHRAFEDELSGRRAQLQQTLRLGEEEKREAERDAQAAR--ARSAELDKLWASLELAASRRAERLRASEALHQLLSDSADVEAW--ARDASLLVAAGGDVGNDEFSTQALARKHRDVVEEIEGYRIDSLQEQAAALPASLAEPAG-----------VRERLRRLEEAYGELAALAAERGRRLQDALALYTIHSETAACLLWLDEKSQWLDALD-IPEKLEDLEVVQHRFESLEPEMNGLASRVAVVNQLARQLLGSEHASEDDIKAKQDLLNARWSEFRELAESKKEALQAQLTLQSFQLECHETQAWIREKTRLIESTQGLGNDLAGVMALQ---RKLSGMERDLAAIEVKVGDLQGEAERLAQHHPERAGA---VRGQLADTADVWGALRGTLRAREDSLGEASKLQKFLQDVDDFQAWLSKTQKAVASE----DVPSTLPEAEKLLAQHEAIKNEISNYS 1015
BLAST of Spectrin beta chain vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004049.1 (pep scaffold:Pmarinus_7.0:GL476488:489896:554954:1 gene:ENSPMAG00000003699.1 transcript:ENSPMAT00000004049.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 778.859 bits (2010), Expect = 0.000e+0 Identity = 417/968 (43.08%), Postives = 620/968 (64.05%), Query Frame = 1
Query: 229 ADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCD--QDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAI 3126
ADERE VQKKTFTKW+NS L V+ +I DLY DLRDG+ L+ LLE+LS E +PKPT+G+MRIHCLENV+K L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + S KSAKDALLLWCQMKTAGYP+V + NFT SWR GL F ALIHKHRPDLIDF + + D N+ AF++AE LG+ LLD ED+ V PDE+SVITYV +YYHYF+ +KA +V KR+ K+L +E +QMI+ Y SL S LL+WI TI +LN R F+NS+ G+QQQ+ F+ YRT EKP+KF EK +LEVLLFTI+S + KV+ P E +S IN AW+ L AE+ RE ALR+EL+RQEKL LA++F++KAA+RESW+T+N L+ + + G++L V AA KKHEAIETD+ AYEE + + ++ L+ E Y+D+ + ++ VL LW+ L + L RR L+ + + ++E + + + + ++GKHL+ V++LL+ H L+E+D + R+ + + A ++ + D Q + S AM++ ELL +R+ L S +W+ + + S EE WI+E I+++ D G DL+S+ RLL K + E EL + + + +G+ +V+ + IA + ++ +LW L + RK++ LE Q+++D DDA+ W + RL +G T+ L +K++ +E + NY I ++ QA +L + V+ ++ +++Y DLL +A + +++L DAL +++L +++D+ WI EKQK+L + +E+LEV++HRFE E E++ + ++ VN ++E+L+ +G+P+ I +DNLN+ W+ V K++ LLS N+ ++C++T WI++KIKL+ S +LG DL VM QR++ ++RD+ AI
Sbjct: 1 ADEREEVQKKTFTKWVNSHLSRVSCRIGDLYADLRDGRMLIKLLEVLSGERLPKPTKGKMRIHCLENVEKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDSREVKSAKDALLLWCQMKTAGYPNVRVHNFTTSWRDGLAFNALIHKHRPDLIDFDALDPADPYGNMQTAFNVAEQKLGLTQLLDAEDIAVEHPDEKSVITYVVTYYHYFSKMKALAVEGKRIGKVLESAMETDQMIEKYDSLASDLLDWIEQTIAILNNRTFANSLTGVQQQLQAFSSYRTVEKPAKFTEKGNLEVLLFTIQSRMRANNQKVFLPGEGKLISEINKAWERLEKAEHERELALREELIRQEKLEQLARRFDRKAAMRESWLTENQCLVLQDNFGSDLAAVEAATKKHEAIETDMAAYEERVHAVLHVAQELQAENYHDVARVAARRDNVLRLWRYLQELLCGRRARLEANVALQRTLHEMLHLLHSMEELKGRLLSQDFGKHLLGVDDLLQKHALLEADAAVLATRVHNVTAAARKFAENSDGYQACDPQVVSARVAMLE-------GCLDELLRMAAERRAGLLESRRLWKLVGEISEEEAWIREKERILSSDDFGRDLTSIVRLLSKQRALEDELQHREQRVRQAVADGRGMVEERHFAADKIAERAGNLLSLWSELGRAAALRKLR-LEQAASLQFLADADDADAWTMDHFRLVSSGDIGHDEFSTQALAKKHRDIVEEIGNYASAIRGLQEQADALPD-EVARCGGVSDRMSNTKQQYGDLLQLAAQRKQQLDDALALFKLFSEADACELWIDEKQKWLDQLEIPEKLEDLEVVQHRFEGLEPEMSAQDSRIGVVNGVAEHLIRDGHPSETAIHAKRDNLNSRWDVFRKHVAQKKEALLSALSIQNYHLECRETNSWIQDKIKLVASTQDLGNDLAGVMALQRKLFGIERDLAAI 959 HSP 2 Score: 69.707 bits (169), Expect = 8.224e-12 Identity = 83/379 (21.90%), Postives = 164/379 (43.27%), Query Frame = 1
Query: 4612 QFLQDCDDEIDWMNEKIDLIRNR--SKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINS---KDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPDEYK--GIVKDVEDN----FNSLKIICAEKKTEI----SLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDL 5703
+ + + +E W+ EK ++ + + + +I LL Q +++++E+++R +V + + + M++E H + + L L + + Q A +FL D + +W +D LV + D+ + + +K +++ EI NY I ++ +LPDE G V D N + L + A++K ++ +LF ++ + E WI E+ K + + L+ +++ RF E + S++ N + LI+ HP +I +D +N W + + + + L SA + ++ + + IQ+K + DLG D V LQRKL E+DL
Sbjct: 594 KLVGEISEEEAWIREKERILSSDDFGRDLTSIVRLLSKQ------RALEDELQHREQRVRQAVADGRGMVEERHFAADKIAERAGNLLSLWSELGRAA-ALRKLRLEQAASLQFLADADDADAWT----MDHFRLVSSGDIGHDEFSTQALAKKHRDIVEEIGNYASAIRGLQEQADALPDEVARCGGVSDRMSNTKQQYGDLLQLAAQRKQQLDDALALFKLFSEA----DACELWIDEKQKWLDQLEIPEKLEDLEVVQHRFEGLEPEMSA-QDSRIGVVNGVAEHLIRDGHPSETAIHAKRDNLNSRWDVFRKHVAQKKEALLSALSIQNYHLECRETNSWIQDKIKLVASTQDLGNDLAGVMALQRKLFGIERDL 956 HSP 3 Score: 65.855 bits (159), Expect = 1.085e-10 Identity = 97/498 (19.48%), Postives = 209/498 (41.97%), Query Frame = 1
Query: 1987 RKEILKHS---HLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFK-RLFDLKFLGDKMSFTEILIRKN---QQNMEIVENYRDNI-EQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQL 3456
R+E+++ L +F A++ E W+ E ++ + G DL++V+ +KH+ E ++++ + L + L + +AA+ +++ LW L + R+ +L + + + + ++E K RL F G + + L++K+ + + ++ N+ R A++ GY D Q V+ ++ +E +LL +A + + LL++ +++L+ + +WI EK++ L + D+ + L + E EL R ++V +V + I NL + W+++ + R L + F D W + +L+ S D +G D S ++ + +I + I L Q D + R + ++ Q++ L QL R L + + + + D W+ + Q + IPE + E + +++ EM+A + ++
Sbjct: 363 REELIRQEKLEQLARRFDRKAAMRESWLTENQCLVLQDNFGSDLAAVEAATKKHEAIETDMAAYEERVHAVLHVAQELQAENYHDVARVAARRDNVLRLWRYLQELLCGRRARLEANVALQRTLHEMLHLLHSMEELKGRLLSQDF-GKHLLGVDDLLQKHALLEADAAVLATRVHNVTAAARKFAENSDGYQACDPQVVSARVAMLEGCLDELLRMAAERRAGLLESRRLWKLVGEISEEEAWIREKERILSSDDFGRDLTSIVRLLSKQRALEDELQHREQRVRQAVADGRGMVEERHFAADKIAERAGNLLSLWSELGRAA-ALRKLRLEQAASLQFLADADDADAWTMDHFRLVSSGD-IGHDEFSTQALAKKHRDIVEEIGNYASAIRGLQEQADALPDEVARCG-GVSDRMSNTKQQYGDLLQLAAQRKQQLDDALALFKLFSEADACELWIDEKQKWLDQLEIPEKLEDLEVVQHRFEGLEPEMSAQDSRI 856 HSP 4 Score: 59.3066 bits (142), Expect = 1.087e-8 Identity = 133/694 (19.16%), Postives = 298/694 (42.94%), Query Frame = 1
Query: 1351 LAQKFNKKAALRESWITDNMELLQKQSLGNNLPTV---LAALKKHEAIETDI-YAYEENLIGL-----TKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHER----REHLDNYLQVYTLINEFCEVQAII-TGITAKQRI---DNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQ----EFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDI------AHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNF-IPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNN-QDNLNNSWNKMADIVD---SKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWL 3336
+ +K++ A+ WI + +L ++ N+L V L A + +E + + NL L +++ N ++ +I+ NK W++L + HER RE L ++ L F A+ + +T Q + DN+G L VE + HE IE+D+ + +R+ ++ A Q+ ++ N + A + +R++ ++ + L + L R+ L+ + + + + + ++EL + + D G L VD LL+KH + E + + + N + + S Q + ++A+ ++ + L+ R+ LLE ++ V + + E WI E +R+ G ++ L+ K Q+ +E +R+ +++R G +V+ + A D+I ++ +LL + A +++ L+ + L D+D +W + + + + I D+ + K ++ E E+ A + + ++ L P+ D ++N+ + D++ ++ +L F + WI EK K ++ + E+ E LE + Q R ++ ++ A +++I + + ++R S I + D ++ W++ ++ + + L + I + + + ++W+
Sbjct: 255 MIEKYDSLASDLLDWIEQTIAILNNRTFANSLTGVQQQLQAFSSYRTVEKPAKFTEKGNLEVLLFTIQSRMRANNQKVFLPGEGKLISEINKA---WERLEKAEHERELALREELIRQEKLEQLARRFDRKAAMRESWLTENQCLVLQDNFGSDLAAVEAATKKHEAIETDMAAYEERVHAVLHVA--------QELQAE-NYHDVARVAARRDNVLRLWRYLQELLCGRRARLEANVALQRTLHEMLHLLHSMEELKGRLLSQDFGKHLLGVDDLLQKHALLEADAAVLATRVHNVTAAARKFAENSDGYQACDPQVVSARVAMLEGCLDELLRMAAERRAGLLESRRLWKLVGEISEEEAWIREKERILSSDDFGRDLTSIVRLLSK-QRALEDELQHRE--QRVRQAVAD--GRGMVEERHFAA--DKIAERAGNLLSLWSELGRAAALRKLRLEQAASLQFLADADDADAWTMDHFRLVSSGDIGHDEFSTQALAKKHRDIVE-EIGNYASAIRGLQEQADAL-----PDEVARCGGVSDRMSNTKQQYGDLLQLAAQRKQQLDDALALFKLFSEADACELWIDEKQKWLDQL-EIPEKLEDLEVVQHRFEGLEPEMSAQDSRIGVVNGVAEHLIRDGHPSETAIHAKRDNLNSRWDVFRKHVAQKKEALLSALSIQNYHLECRETNSWI 922
BLAST of Spectrin beta chain vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000684.1 (pep scaffold:Pmarinus_7.0:GL483163:49540:93186:-1 gene:ENSPMAG00000000623.1 transcript:ENSPMAT00000000684.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 337.421 bits (864), Expect = 4.207e-102 Identity = 193/486 (39.71%), Postives = 294/486 (60.49%), Query Frame = 1
Query: 256 KTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPED-VNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVS---KLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGN-NLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNK-VLDLWKKLLQTLHERREHLDNYLQVYTLINEF 1695
+TFT W NS L +I+ + D RDG L++LLE++S+E +PKP +G+MR+H + NV+K L F+ ++ V L ++GA +IVDGN ++TLG+IWTIILRF +QDI + SAK+ LLLWCQ KTA Y +VN++NF SW+ GL F ALIH+HRPDLID+ ++D I NL+ AF++AE L IP +LD ED VN PDE++++TYV+ YYH F+ + + R+ K+L + + + L + V +LLEWI TI +L R N++P +Q ++ F YR KP K +K LE+ T+++ + + P E +S I +AW L AE G E L E+ R E+L +LA+KF +KA + +SW ++LQ++ + +L + A LKKHEA E+D+ A+++ + + I+ L + Y+D+ S +NTK K + D W L + R++ L +V I+
Sbjct: 4 QTFTAWCNSHLRKAGTQIDSIDEDFRDGLKLMLLLEVISSERLPKPEKGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNTKMTLGMIWTIILRFAIQDISIEN------TSAKEGLLLWCQRKTAPYKNVNVQNFHTSWKDGLAFNALIHRHRPDLIDYDKLRKDDPIGNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSCYYHAFSGAQKAETAANRICKVL---AVNHERVDLSCACVRARLQLLEWINRTIPVLEDRNTQNNMPAMQGKLEDFRDYRRVHKPPKAGDKCQLEINFNTLQTKLRLMNRPAFMPSEGKLVSDIGNAWSHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKAKIHKSWTEGKQQMLQQKDYESVSLAELKALLKKHEAFESDLAAHQDRVEQIAAIAQELNDLNYHDVAS-VNTKCKEICDEWDDLGEWTQTRKDSLSRTEKVLETIDHL 479
BLAST of Spectrin beta chain vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009295.1 (pep scaffold:Pmarinus_7.0:GL479988:2885:20778:1 gene:ENSPMAG00000008383.1 transcript:ENSPMAT00000009295.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 337.421 bits (864), Expect = 3.889e-98 Identity = 190/481 (39.50%), Postives = 289/481 (60.08%), Query Frame = 1
Query: 259 TFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPED-VNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGN-NLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEF 1695
TFT W NS L IE++ D R+G L++LLE++S E + KP RG+MR+H + NV+K L F+ ++ V L ++GA +IVDGN ++TLG+IWTIILRF +QDI +E SAK+ LLLWCQ KTA Y +VN++NF SW+ GL F ALIH+HRPDLID+ ++D I NL+ AF++AE L IP +LD ED V PDE++++TYV+ YYH F+ + + R+ K+L E+E++++ Y+ + S LL+WIR T L N R N++ +Q ++ F YR KP K EK LE+ T+++ + + P E +S I + W L AE G E L E+ R E+L +LA+KF +KA + E+W +L+K+ + +L + A L+KHEA E+D+ A+++ + + I+ L E Y+D+ S+ + W KL R++ L+ +V I++
Sbjct: 1 TFTAWCNSHLRKAGTGIENIDEDFRNGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEE------TSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPDLIDYEKLRKDDPITNLNNAFEVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSCYYHAFSGAQKAETAANRICKVLAVNQENEKLMEDYEHMASDLLDWIRRTPWLEN-RVPENTMQAMQGKLEGFRDYRRVHKPPKAQEKCQLEISFNTLQTKLRLMNRPAFMPSEGKMVSDIANGWSMLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKAKIHEAWTAGKEAMLEKRDYDSVSLTELKALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDVASVNARCQDICAEWDKLGDLTQRRKDTLERTEKVLETIDQL 474
BLAST of Spectrin beta chain vs. Ensembl Yeast
Match: SAC6 (Fimbrin, actin-bundling protein; cooperates with Scp1p in organization and maintenance of the actin cytoskeleton; phosphorylated by Cdc28p/Clb2p in metaphase on T103, to regulate conformation, and modulate actin filament binding affinity and actin cable dynamics; relocalizes from the plasma membrane to the cytoplasm upon DNA replication stress; human homologs PLS3 and LCP1 implicated in spinocerebellar ataxia type 2 (SCA2) can each complement yeast null mutant [Source:SGD;Acc:S000002536]) HSP 1 Score: 55.0694 bits (131), Expect = 1.218e-7 Identity = 68/240 (28.33%), Postives = 103/240 (42.92%), Query Frame = 1
Query: 235 ERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIV------PKPTRGR--MRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDA----LLLWCQMK-TAGYPSVNIRNFTNSWRTGLGFVA-LIHKHRPDLIDFS----SCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVAS 900
ERE + FT W+NS + V + L+ DL+DG LL E + V +P G R LEN + + + L + DIVDGN LTLGL+W ++ R ++ S +D +L W Q + T G + IR+F + + F+ +++ P +D+ + N LA IA LG L PED+N R +IT++AS
Sbjct: 411 ERE---ARVFTLWLNS--LDVDPPVISLFDDLKDGLILLQAYEKVMPGAVDFKHVNKRPASGAEISRFKALENTNYAVDLGRAKGFSLVGIEGSDIVDGNKLLTLGLVWQLMRR------NISITMKTLSSSGRDMSDSQILKWAQDQVTKGGKNSTIRSFKDQALSNAHFLLDVLNGIAPGYVDYDLVTPGNTEEERYANARLAISIARK-LGALIWLVPEDINE--VRARLIITFIAS 636
BLAST of Spectrin beta chain vs. Ensembl Nematostella
Match: EDO42431 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1C0]) HSP 1 Score: 1107.05 bits (2862), Expect = 0.000e+0 Identity = 716/2112 (33.90%), Postives = 1175/2112 (55.63%), Query Frame = 1
Query: 190 TSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSD---DIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELG--EDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKD--IEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKM-LSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDG---------------------LSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIR 6399
+++FERSRIK LADERE VQKKTFTKWINS L V ++ +LY DL+DG+ L++LLE+LS E +PKP++GRMRIH LENV+K L FL Q+VHLENVGAHDIVDGN ++TLGLIWTIILRFQ+QDI E + +SAKDALLLWCQ KT GY V I NFT SWR GL F A+IH+HRPDLI+F + D NL AF++AE LGI LLD EDVNV PDE+S++TYVA+YYHYF +K V R+ K++ ++ E+E++I Y+ L S LLEWI I L R+F+N++ G+QQQM FN YRT EKP +FVEK +LEV LF + S + K Y PPE + IN AW+ L +E+ RE ALR+ELMRQE+L LA KF++K A+RE+W+ +N L+ + GN+L V AA KKHEAIETDI AYEE + + +++ L E Y+D I K +++ LW+ LL + +RR L+ +Q+ + E + + I ++YGKHL+ VE+LL+ H L+E+DI + R++ + ++A ++ D++ ++ + ++A I++ + ++ELL R+ L+ S + F +A EE W+ E + + D G+DL++ LL KH+ E E++++ + G+ L++ P + I + + I++ W+ L D+ RK K+ E L Q++++ +D W D +R+ LG E+L++K+ E ++ Y ++ Q LG V + + ++++Y LL A ++KL DAL++++L ++ V +WI E++ L + D D+EE +V++ RFE F+ EL +V VN L NL+ G+ N I D LN W + D + KR +L F+ +T WI EK L+ + +++ +DL +VM QRR+N++QRD+ A+E K L ++ ++ ++ ++ +V W ++ ++ RD LA ++ RF+ LDDF WL E+AS++IP S SEAE+ + ++ +DE+ E ++ ++ G + + E D Q L+ +++ + WK L L E +++ L + L +F DA+Q E +L Q+ +L K+ + + ++ E++ ++E F +M + DEK+ ++ + + L + + +D++ K QNL ER N + +L++ + L + +QD +D+ D L EK QV +E S + + + + +A E E+ A + ++++++ G+ + + P K EI + L L+ W EL++ + K L R++ F Q+M +W+K +E I+ ++ + +T+ T +K H +L KQ N K + ++L+ Q +D L PL K + +Q + QF +D DDE W+NEK L+++ + L + Q+LQ +H+++ EI + + + ++ H + + +L++ ++L ++ + ++ L L +++ D +E SW+SE+EL++MG KD+ ++++ + LE I +Y + E ++ L P+ + ++ ++ + LK + E++ ++ +T +LYQ ++E WI ++ ++A S D G+DL C LL ++F F+ +T IG+ +V N D+LI H A +I+ WKD INE WADLLELI+TR ++L++A +LH++Y D++ +L IQEK + M +LG+D SV LQR ++FE DL L ++ + LL Y +K + + K E++ A+++L + R + D + FL V++ + W+ ++ + K +DVSG+E+L+ H+S +E++ +EE+F + +G LL H S EI+ K + +D + +W +HL L++EV Q+ARDA +AEAW+++QESYL NENLG+ L E LL+K F+K QEE+F L+RLT E+R
Sbjct: 6 AARLFERSRIKVLADERERVQKKTFTKWINSHLQRVGARVNELYHDLQDGRKLILLLEVLSGEKLPKPSKGRMRIHNLENVEKSLVFLKKQRVHLENVGAHDIVDGNQKITLGLIWTIILRFQIQDITI-EGETTEKRSAKDALLLWCQSKTVGYVHVTITNFTTSWRDGLAFNAIIHRHRPDLIEFEKLTKADAEQNLEQAFEVAETQLGITPLLDAEDVNVDFPDEKSILTYVAAYYHYFAKMKTVEVSGSRIGKVIERIKENEELIIDYEKLASDLLEWIEIKIIQLGEREFANTLLGVQQQMLEFNQYRTQEKPPRFVEKGNLEVQLFILTSKIRANHQKPYIPPEGRGMIDINRAWERLEKSEHERELALREELMRQERLEMLAAKFDRKYAMRETWLNENQRLVAVDNFGNDLAAVEAATKKHEAIETDIMAYEERVNAIVAVAEELHRENYHDSERIQVCKGRIIQLWELLLVLIKQRRVRLEKCMQLQRVFQEMINIIDWMDEIKIGLLSEDYGKHLLGVEDLLQKHSLVEADIAAQADRVKTVNAQAEAFLHVEDEEGKTQ-HKPDEAQIRDHQAELEGAYNELLQLAAARRARLEESLKLQSFYRNADEEEMWVTEKDYFVQSTDYGHDLNTAMILLTKHEAVEREMTARNAQTKAVARNGEELLEAVPYATDTIQNRLDTIRSKWDKLHDNAAYRKKKIQENLKLQQFIAEYNDIMSWCDMMERIVANDDLGYDEHSAEVLVKKHHAVEEGIQGYASEVKAFHCQVDG-LGDEDKSSPEVVDRCNTLDERYSALLQQAAARRQKLQDALSLHKLNREAYIVETWIDERENRLDTALTVDKGMDLEECQVIEQRFEGFQQELDANERRVQLVNELGGNLIEKGHINSDEIKETIDRLNTRWCNLRDTANQKRAKLDKALRLQQFYAQTLETKTWISEKSSLLITEEDVTNMKDLATVMVLQRRLNNIQRDLPALEDKCTSLENDAQQLCSEYEGEPEEEIVKEKITVVSSSWVEMKDNVKQRDEALAESGELQRFVIDLDDFQIWLRHTHNEVASEDIPNSLSEAERSLKEHEDIKDEIDTHEPDFQKLIEDGPKWAQDESDLQQ-QSLKEQLDQLQSGWKDLLVLWENRKRLLIQALNHQLFIRDAKQCEALLGQQDLFLSKE---------EVGATVEAVQELIKKHEEFSKRMDVQDEKINQMI-QFAQRLANDGHYAQDKITEKAQNLHERRNANRQKLEAALQRLRDALQLQQFIQDAEDMYDWLNEKHQVASEESYRDLSNIQGKVMKHEAFEAELQANKERLDQISESGRDLADEKPENKPEIDELLQKLDQKWLELAEVSKHKGSKLKDAQRQEEFNAGVQTMQEWVKELETVIITQEKA----TDLTTATRLYQK--------------------HKQLEKQINA-KKERLKELDAQAADMVDAGHFDPNAVQETKIILEEKYECLEAPLAEKGAELDQAMQFFQFDRDVDDEETWINEKEPLLQSTNYG----NNLFEVQKLQKKHQTLCAEIDIHQKHKERICNQGDELVLGYHPQAEDIERRRKELEEKWDDLKKQSDAYKAQLDLSLQAKQYYFDAAEAESWMSEQELNMMGDE-RGKDEASATEMLKRHETLEAAIADYAETVNELGETANGLVESNHPESEQIKIRQNQIDKLYAGLKDLAEERRGKLD------ETLKLYQLNREVDDLELWIADKEQVAGSQDIGQDLAHCELLIEKFRDFARDTTHIGTERVASTNGVCDQLIGTGHSDAATIAEWKDGINESWADLLELIETRTKMLEAALELHKYYHDAKEVLAMIQEKDNLM--TEELGRDLNSVQQLQRTHQSFEADLAPLGHQVSGIQEEAGRLLGSYAGEKASEIQAKEDEVVQAWKNLNLRVRQRTDKLHDADDLYRFLIAVQDQMLWMNDMLKHILTYEKAKDVSGVEVLMDQHQSRHVEIEGREESFFGVIKMGEQLLAKSHYASAEIREKINMLHRHKDEMLLEWKKRWEHLGLILEVMQFARDAYTAEAWIMAQESYLRNENLGIDLAEVEKLLEKHGNFEKVVAAQEERFLALERLTQFELR 2065 HSP 2 Score: 78.5666 bits (192), Expect = 3.706e-14 Identity = 44/124 (35.48%), Postives = 60/124 (48.39%), Query Frame = 1
Query: 6841 MKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPST 7212
M+G L+RK + N+KA+ R W YV+L + FFKD++ + + PL + V A DY KR VFR R NG E+LFQ DM W+ + + QV S PST
Sbjct: 2159 MEGYLHRKPTMDGPNRKAAIRQWKQYYVILRDMELHFFKDQK----SARNDHAAAHPLATLDSVCEVASDYTKRKHVFRFRVSNGQEFLFQAKDEEDMNIWIKHVQECA----QVPESPAKPST 2274
BLAST of Spectrin beta chain vs. Ensembl Nematostella
Match: EDO49576 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGP7]) HSP 1 Score: 531.176 bits (1367), Expect = 2.192e-165 Identity = 302/789 (38.28%), Postives = 472/789 (59.82%), Query Frame = 1
Query: 187 VTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDL---KFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSI 2544
V + FE+ RIK L +ER QKKTFTKW+NS L + + DL+ DL DGK L+ LLE++S E + RG+ R+H ++NV+K L FL + V LE++GA D+VDGN RL LGLIW IILRFQ+ DI + +D S KSAK+ALLLWCQ T GYP V+I+NF+ SWR GL F AL+HKHRPDLID+++ + + NL+ AF +A LGI LLD EDV+ P PD+RSV+TYVA+YY YF LK+ +R+ K++ ++E E+M + Y+S+VS LL WI + I L R F +I +Q+++ F +RT EKP K+ E+V++E LF +++ + + + + PPE + IN AW + +AE+ R ALR EL+RQ+ L +A+KF +KA LRESW+ D ++++ + LG + TV AALK+HEAI TD+ A EE + ++ L +E Y I ++ ++ W KL++ L RR L + Q+ + + A + I A R ++YG+HL++V+ +L H L+ES I+S ++R + ++A +V +IK+++ + F L+ +R+ L+ S ++ F D E+ +IKE + + ++G DL+S+ RL ++H+ E E++ + E + +G+ L+D G + I AK +Q W L + +R+ +L + QY SD +DAE W+ E ++F + + D+ S +L R + EI + + D+I Q++ Q++ L+G +I
Sbjct: 4 VEAPTFEKDRIKTLKNERIFSQKKTFTKWVNSFLDKSGLHVNDLFEDLADGKILISLLEIISGEKIGFAARGKFRVHNIQNVNKALEFL-QKSVKLESIGAEDVVDGNERLILGLIWMIILRFQIADISYQDDMSKERKSAKEALLLWCQRMTRGYPGVDIQNFSTSWRNGLAFNALLHKHRPDLIDYATLRPSQHEANLNNAFTVAAEKLGITRLLDAEDVDCPRPDDRSVMTYVAAYYQYFAKLKSEETGGRRIAKIIGVIMEIEKMEKSYESMVSDLLHWISSKITEL-ARPFEKNIFAVQRELGAFKHFRTVEKPPKYTERVNIEAHLFNLQTKRKANNQRPFAPPEGKLVKDINRAWQVMESAEHERAQALRNELIRQQMLEKMAEKFQRKADLRESWLDDMVQVIDDELLGQDAATVEAALKRHEAISTDVKAREERFQMVFNLAQELIDEDYYKADVIRKREDVIMVKWDKLVKKLEARRNTLTGFTQLVGVFRDMDSAHADMLDIEAGLRSEDYGRHLLDVQNMLDKHSLVESQIQSQHERTLAINTQAQSFVA---------AKHPETEVIKQRQRLLTQAFQALVQLGKERRARLEDSLELYTFFEDVEEEDIFIKETDKLAASKEVGRDLASLTRLQQRHEALEAEINGRFSHCEGIIAKGQALIDKGHFGAKEIKAKIKQLQANWIKLKELAGTRRERLKDAAQSLQYYSDANDAESWMKE--KMFVVCSEDYGRDEQSAVSLLQRHSHIEDEI-KAFADDIAQLKEQSK-LMGEAI 777 HSP 2 Score: 85.5001 bits (210), Expect = 1.746e-16 Identity = 80/388 (20.62%), Postives = 163/388 (42.01%), Query Frame = 1
Query: 2023 QFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWI----------DEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQ 3156
+F A L E W+ ++V ++++ LG D ++V+ L++H+ ++ ++ + + L+D + I + + I W+ LV E+R+ L D D A + D + L D++ + DK S E I+ + I QAQS + + + + ++ + + +Q L+ + + + +L D+L +Y D + +I E K + D+ L L+ R E E+E+ R + + L+ G+ + I L +W K+ ++ ++R+ L ++ D W++EK+ ++ S D G D +S + +R +H++ +I A I L Q
Sbjct: 393 KFQRKADLRESWLDDMVQVIDDELLGQDAATVEAALKRHEAISTDVKAREERFQMVFNLAQELIDEDYYKADVIRKREDVIMVKWDKLVKKLEARRNTLTGFTQLVGVFRDMDSAHADMLDIEAGLRSEDYGRHLLDVQNMLDKHSLVESQIQSQHERTLA----------INTQAQSFVAAKHPETEVIKQRQRLLTQAFQALVQLGKERRARLEDSLELYTFFEDVEEEDIFIKETDKLAASKEVGRDLASLTRLQQRHEALEAEINGRFSHCEGIIAKGQALIDKGHFGAKEIKAKIKQLQANWIKLKELAGTRRERLKDAAQSLQYYSDANDAESWMKEKMFVVCSED-YGRDEQSAVSLLQRHSHIEDEIKAFADDIAQLKEQ 769 HSP 3 Score: 81.2629 bits (199), Expect = 3.547e-15 Identity = 91/448 (20.31%), Postives = 199/448 (44.42%), Query Frame = 1
Query: 2197 EGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAME---QQLEEWMKI-GKDFLKSEQDKDQFVRLQ 3528
EGK + DI+ Q +A++ Q L L+ R+ L +M + +Q +D E W+D+ ++ D + LG + E +++++ V+ + + + N AQ L+ + K+ D I K+ L+ + L + + D DS + + + + L + + +++ + + + ES++ + E+ +N +++ V +P ++I Q L ++ + + +R L FF D ++ +I+E KL S E+G DL S+ + Q+R ++ +I + + ++A+G ++ AK+I+ ++ + W L++L R L + ++ +D +W+ + + S++ + A L+ +++ DE+ A QL+E K+ G+ + Q FV L+
Sbjct: 352 EGKLVKDINRAWQVMESAEHERAQALRNELI-----RQQMLEKMAEKFQRKADL--RESWLDDMVQVIDDELLGQDAATVEAALKRHEAISTDVKAREERFQMVFNLAQELIDEDYYKADVIRKREDVIMVKWDKLVKKLEARRNTLTGFTQLVGVFRDMDSAHADMLDIEAGLRSEDYGRHLLDVQNMLDKHSLVESQIQSQHERTLAINTQAQSFVAAKHPETEVIKQRQRLLTQAFQALVQLGKERRARLEDSLELYTFFEDVEEEDIFIKETDKLAAS-KEVGRDLASLTRLQQRHEALEAEINGRFSHCEGIIAKGQALIDKGHFGAKEIKAKIKQLQANWIKLKELAGTRRERLKDAAQSLQYYSDANDAESWMKEKMFVVCSEDYGRDEQSAVSLLQRHSHIEDEIKAFADDIAQLKEQSKLMGEAIKNTSQQVPHFVSLK 791
BLAST of Spectrin beta chain vs. Ensembl Nematostella
Match: ALPHA-ACTININ (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4X0]) HSP 1 Score: 361.688 bits (927), Expect = 1.017e-105 Identity = 227/590 (38.47%), Postives = 328/590 (55.59%), Query Frame = 1
Query: 163 EDEVQYANVTSKVFERSRIKALADER-ENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPED-VNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGN-NLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLIN----EFCEVQAIITGITAKQR---IDNYGKHLM-EVEELLRSHELIESD----------IRSINQRLEKLISEANRYV 1869
EDE +Y F K L D E QKKTFT W NS L +I ++ DLRDG LL LLE++S E +P P RG++R H + NV+K L F+ + V L +VGA +IVDGN ++TLG+IWTIILRF +QDI ++ + AKD LLLWCQ KTA Y +V+++NFT S++ GL F ALIH+HRPDLID+ S + D + NL+ AFD+AE L IP +LDPED V PDER+V+TYV+SYYH F S + + KR+ K+LN ++E+M++ Y+ L S LL+WI T+ L R ++ +Q++++ YR GEKP K EK LE T+++ +S Y P E ++ IN AW L AE E L E+ R E+L +LA+KF K + ESW +L K + L + A +KKHEA E+D+ A+++ + + I+ L Y+ I + + D WK L + R + L++ Q ++ EF + A R +D + H + E++ELL +HE + + I I ++E L + N Y
Sbjct: 3 EDEQEYYGY----FYGEEDKGLLDPAWERQQKKTFTAWCNSHLRKTGKQIGEIEEDLRDGVLLLQLLEIISGERLPHPERGKLRFHRIANVNKALDFVAGKGVKLVSVGAEEIVDGNLKMTLGMIWTIILRFAIQDIAIEDSF------AKDGLLLWCQRKTAPYKNVSVKNFTTSFKDGLAFCALIHRHRPDLIDYDSLRKEDPLYNLNKAFDVAEQYLDIPRMLDPEDMVETERPDERAVMTYVSSYYHAFTSSQQADTAAKRIGKVLNINRDNERMMEDYERLASDLLDWINKTMPWLTSRDTDGTLKDMQRKLDELRNYRKGEKPPKVEEKGQLETNFNTLQTKLRLSNRPAYLPSEGKMINDINDAWGGLEMAEKDFEDWLLMEMRRMERLDHLAEKFRHKCNIHESWTNGKDAVLSKDDYSDATLADINALMKKHEAFESDLAAHQDRVDQIVAIAQELNALEYSKIDEVNARCQNICDDWKDLGELTMHRLQKLEDAQQRLQSLDQLRLEFAKKAAPFNNWLESAREDLMDMFSVHTVEEIQELLDAHEAFKENMPAAQAEYNSIMDIAVQIESLSGQENPYT 582
BLAST of Spectrin beta chain vs. Ensembl Nematostella
Match: EDO29101 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4L2]) HSP 1 Score: 342.813 bits (878), Expect = 1.148e-105 Identity = 175/364 (48.08%), Postives = 245/364 (67.31%), Query Frame = 1
Query: 187 VTSKVFERSRIKALADERENVQKKTFTKWINSTL--IHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAW 1272
V + FE+ RIK L +ER QKKTFTKW+NS L + + + DL+ DL DGK L+ LLE++S E + RG+ R+H ++NV+K L FL + V LE++GA D+VDGN RL LGLIW IILRFQ+ DI + +D S KSAK+ALLLWCQ T GYP V+I+NF+ SWR GL F AL+HKHRPDLID+++ + + NL+ AF +AE LGI LLD EDV+ P PD+RSV+TYVA+YY YF LK+ +R+ K++ ++E E+M + Y+S+VS LL WI + I L R F +I +Q+++ F +RT EKP K+ E+V++E LF +++ + + + + PPE + IN AW
Sbjct: 4 VEAPTFEKDRIKTLKNERIFSQKKTFTKWVNSFLDKVRSGLHVNDLFEDLADGKILISLLEIISGEKIGFAARGKFRVHNIQNVNKALEFL-QKSVKLESIGAEDVVDGNERLILGLIWMIILRFQIADISYQDDMSKERKSAKEALLLWCQRMTRGYPDVDIQNFSTSWRNGLAFNALLHKHRPDLIDYATLRPSQHEANLNNAFTVAEEKLGITRLLDAEDVDCPRPDDRSVMTYVAAYYQYFAKLKSEETGGRRIAKIIGVIMEIEKMEKSYESMVSDLLHWISSKITEL-ARPFEKNIFAVQRELGAFKHFRTVEKPPKYTERVNIEAHLFNLQTKRKANNQRPFAPPEGKLVKDINRAW 365
BLAST of Spectrin beta chain vs. Ensembl Nematostella
Match: EDO49575 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGP6]) HSP 1 Score: 313.153 bits (801), Expect = 2.598e-85 Identity = 433/2021 (21.43%), Postives = 864/2021 (42.75%), Query Frame = 1
Query: 1426 QSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNK-VLDLWKKLLQTLHERREHLDNYLQVYTLIN------EFC-EVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIE-HQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEM----------AAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEK-ILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQN-----------------PDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPD----EYKGIVK---DVEDNFNSLKIICAEKKTEI----SLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQ-----NIRRFNSIDS----SLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSA-SPKPATTRTI--------PPEE-----VLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCV---FRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMR--QVNPSNTNPSTTQSHPNLSSSLPPQAQ 7260
+ LG +L + +KHE E ++ E+ + LT S L+ + K VL LW++L + +R L + + Y L N +C E +I + + + + E++E + E + + EK+I + + F +++ I +K + + L S D RKE L ++ + F+ DA + + ++ +LG + V+ LL+KH+ E + S+ L + GK L+D + I + + + + E L + R+ KL Q+ D ++E WI E + + D ++ L + E+ + R I+ +R++ + L+ V +++ + ++++LL+ + KL +A + + D S IT+K+ + + D E L+ + + F+ +L A +V +N L+E L+ G+ I Q+ L WN++ D +R +L F +C+ I EK +++ E+G DL +V R+ + ++R++ IE K++ L + ++R A+ ++ Q D++ Q WE L L R L + F+ D +W+ + T M+S + ++ +AE ++ + ++ +M A L E + D +K Q+ D V ++ + Q K++ L++ MF DA + E I N Q ++ S+ +L ++ ++ + F + + E+ + + K + + + + +++K + ++W+ A +R KL E LL + L+D +L+ + EK+Q+ E S + L + + E E++A++ ++ + + G+ + P ++ + L +L W+ L + K Q L +++ FE + + W++ +E + ++D RS + N +K+ S M++ + + SELLKQ D A ++EQL + E +L + + + QFL D E+DW+ +K + +K + LL Q L + + +++EI + + V +L++ ++++ H + L + E L + L LA ++ V E+ +W+SEK L L+ +D+ ++RK L++E+ KI + + L D E+ + K ++E+ + L+ + ++ + LF + EL AW+ E+ I SDD G+DL+ +L +F +F+ + G ++ + + L+ +H + I + I E W L E TR++ L A DLH + + IQEK ++ V + D + V LQRK + F++DL L ++ + ++ L K LI ++QE+ A++ L+++ ++ + L+ FL R+L+ WIE + Q+ + +E L+A ++ L+ E+DS+ + + LL + + + +I++K + D D L L E+ ++ R+A EAW+ ++E L +E++G +L+ LLKK F+K + Q EKF L T+ + K + +N E+ ++ +T++V KP I E +Q ++ S+ + S S + + F V+ ++ + SS + P K +P N + V NL ++++ S+ S PA + P+E V+++G L R+ + + + A + W +LY +L + F+ D++ F Q V ++ ++ +++ FR+ +G+++LF+ V+D RW + I +++ Q N + T Q P +PP +Q
Sbjct: 1512 EDLGRDLASTQVLQRKHEVFECELVTLEKQIEELTVESARLQATYQGQTARSVEQHEKYVLSLWEELKRKTSRKRRKLHDAYEFYKLGNTVRDLISWCIETSRLIASDDPVHTVSDAERMMRELDEHHAEMDAREESFARVLETGEKMIEDGH----FAEEE------------ITDKLELLLSERERLYASWDTRKEELSEAYYLHVFLKDAKQVDSFTSSQEAVLLCAELGNSVDEVEFLLKKHENTEKLVLSQEEKLSALQVLGKELIDNQHNQSDMIRNRLSGVCDRREKLKAELDKRREKLQNSHKIMQFYQDVVESESWIMEKLQTATDESFKDPINLESKLQKHQAFESELTAHER-AIDSVRDKGEQLISCGHFAASEVEVRIEALYIQWEELLEASATKGRKLQEARDHQQFNQEVDIADSCITDKETIVLSSDYGRDFEHCVRLQRKMKEFDQDLAVDAARVEAINVLAEKLIGQGHAGSVRIQQRQNALTERWNRLQDKASERRQKLAEACEIHAFNRNCRDVSSMINEKAA-VQTSGEVGRDLPAVEALIRKHDDVERELTVIEGKMEELEGEAYRLVRSQPHMARAVQAKQADIIEQ-WERLNDLFDQRKVILEANRLLQIFLVDYRDLMSWMNDLGTRMSSGELADNVRDAEAMLGLHEERKGQMNARMDSYNATVAFGMSLVEQGHVSADVIK--QNVDDLVLENTELQQLWQSRKLM----------LQQSTDLQMFLADAEKAENWIKNKQ----------MVAQSIESRESLDNVESLLKSHINFEKSLSTYEENIRSLESSAKQFLQVKHYHAEAIRSKYLEILDKWEALKKLAASRSGKLGESKLLFQFLRDAKELESWMNEKLQIAAEASYREATNLQQKLQKHQTFEAEVSAHKSELDAITQTGQSLMRNSPSCQETVESRLKDLADLWSLLGDLSDNKAQRLKEAIQKQTFERNVIELQAWIEEVENALASEDYGKDMRS----VNNLIKRHQSLQMDIARYEDRV------SELLKQAGEFVAAEHFLKDEIADRAADVAERFEQL----------VEPATERELRLQD-SLALHQFLADTQVEVDWIKDKEPI----AKSEDYGRNLLGVQSLMKKMEGLESEINSHELLVQALLETGEQLVLRGHYAERDIGAKSQMLLELWEELRINAQTRNEKLQASLATHQYYDQVFEMDAWVSEK-LSLVSSTDYGRDETSAETLLRKHDALQLELDANESKIRDLRSIYSELSDAGDTEFSKLEKIQDELEERYTHLRDVARDRHRRLLDSSRLFNFLREADELG----AWVEEKEAIVSSDDCGRDLEHVEMLMQKFEVFTRDLVSSGE-RIAKLTEHAQMLLDDEHTDSEMIEQRAEVICERWDGLKERTSTRLEELDRARDLHAFRRSVDEIHAWIQEKIDALGVAENGAPDLRHVQALQRKHQGFQRDLQALGEKVDLVLRDADDLSAKVPAHKH-ELIMEKQEVQKAWKKLQQLASSKQSHLLQSEGLQAFLDDYRDLMSWIETTSAQVAEETLGSTFADVETLIAQNQELQTEIDSRANSVEEFQSRADQLLGSGNPSAEDIRNKSSHVRDTWDRLGASLRTRTQQLQHNKEIQRFKREADQLEAWLNAREHDLLSEDVGDSLEAVEELLKKQDEFEKMLLTQGEKFNSLTN-TSFSVHKKSCAPKQ-------VNSEEA------RTVKAVTDSVVA---KPGIDVAKEIPEQMNGLSEVKESKSVSAESMDSFGNASAARTSSPFNAVSPQRQLDSSDKASSTQTSSP-FKAVLPQRPINTADEVTNLINASNLKSSLSESPAEKEQVRSPLEFDPGPKEIQKTLVVLEGMLRRRQELQTAGRNAGSNIWQNLYSVLIDKSLLFYGDKKSFSGGGNQ--------VSPQIELRGSRLHVEEESTNHEFRLLLPDGSQFLFRCKDVLDFHRWTNEIEASTNDGEDVQSNGGHEKIETDQISPMSLDKVPPYSQ 3433 HSP 2 Score: 241.121 bits (614), Expect = 1.965e-63 Identity = 274/1296 (21.14%), Postives = 568/1296 (43.83%), Query Frame = 1
Query: 2548 DHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMD-CQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSE----QDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQ--NPDK-ASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVIN---SKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-------PDEYKGIVKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRL 6381
D VA + I Y L++ + + L A+ Y ++ + + W++ K++ + + ++ ++ ++ + E F +E+ + +V +N L++ L+ +G+ + + + +N W K+ + K +E L++ H F+D C++ WI+EK + +ELG+D+E+V + RR ++RD+ A+E K+ L Q ++ + R A+ I+ + V W IL+ R L F+ D +W +++ S P+ + A +LI ++ + DE+ ++ ++ + G++ L + Q K L+ +++ W ND + D+QS ++ + ++ ++E F+ + + E+ + + KT+I + +D + ++ +++ R A +R+ L +L ++D D+ + EK Q+ + S + K+ L + KA E EI A + I+ +NK GK +++ D L LN W L EK L R++ + + + W+ E ++ ++ +G+ +T + + L+S + +++ EL+ Q N D S E L+++ + L + + S+ QF+ D + E+ W+ E + ++ + +L+ Q+LQ RH + +NE+ N ++D+++ Q +ID + V + +L+ + L + + + L + Q++L + +E SW+++K GL + KD ++ + + L++++ + I+E + L ++ +D+E+ F L + + T ++ + + I A++ E+ + A S+D G D + +++ RF F + N N L+ H +I +D +W L + I R + L SA ++HR+ D L+ IQEK +++ + DLG+D S +LQRK + FE +L+ L+ I S L Y ++ + + ++ + L++ ++ + +F+ + VR+L+ W E + + VS E ++ EMD++EE+F+ L G ++ H EI K + + +R+ L+ W + LS ++ + +DA +++ SQE+ L LG ++DE LLKK +K ++QEEK L+ L
Sbjct: 527 DRDNVAVRQITITNTYNRLIETSEMRRLSLQKAIKYYHFCHECEDMDLWMSNKERQFKSIESQNTLDAIQTVRQKLERFATEIATKCSRVSDINQLADELIQDGHAHSAAVKAKRKEINERWEKLQRL-KVKEEENLAEKHGVELFLDVCEEMRSWIQEKDAAL-CKEELGKDIETVRAQLRRHQGIERDLAAVEDKVAKLQDQAKSLVVRHPRQARQIKAKEGEVISLWAILKSKANKRKGLLDEAYGQQGFLADARDLMSWSAELKESFISAEDPQDIASASELIQQHEEKFDEIQTRFERFDQLDEYGRNLLATSPQAVQVKQSMAALKAEKAALSSSWAKRNDRLHQGL--------------------------------DLQSSVDE----------VEWLLKKHEDFVKTLTAQEEKVRSLADMAKTIIHARHQARDWVASRAESVINRRDNVKNQASDRQKALLTSQVLQNFIRDADEFGGWIKEKSQIAEDESFKDPKNLQGNLKRHKAFEAEITANKDGIDRINKAGKDLIRTKHFGAQKVKDKLKGLNEAWLNLVADTTEKGNKLQQAERQRQLNRAMEDVRIWMNETEA-VLGLEDTGRDLAGVKFLTKKHQLLESD--IEMHATVIVDVADKAQELVSQGHFNSDTIKSDSENLQSRYR----SLLCLTDKRRSVLEDAFALHQFIYDIEVEMTWVREHL----QQASSGDLGTSLISVQRLQKRHLAFENELTNHQTRIDTVLSSGQDLIDSCYSATDKVEERCEELQNLWDELVDMAAQRKQRLHDSFLSQKYLSEANEADSWMNDK----AGLAASQDYGKDGASAETLLTRHKALQVDVAAFSTTIDELAEEARRLVQSSHFDSEKISSTQRDLEEQFCGLNTLVKTRHTRLTESKKLHEYRREVEEISAYVSEQLQTAASEDYGTDFEHLQVIQGRFGDFQRSVASYAENFRNVDN-LAKMLVSEGHTDTVAIKEQQDITRSMWLHLEDQIRLRQKRLTSAEEIHRFNRDLNELISRIQEKDAAINL-EDLGRDLASTQVLQRKHEVFECELVTLEKQIEELTVESARLQATYQGQTARSVEQHEKYVLSLWEELKRKTSRKRRKLHDAYEFYKLGNTVRDLISWCIETSRLIASDDPVHTVSDAERMMRELDEHHAEMDAREESFARVLETGEKMIEDGHFAEEEITDKLELLLSERERLYASWDTRKEELSEAYYLHVFLKDAKQVDSFTSSQEAVLLCAELGNSVDEVEFLLKKHENTEKLVLSQEEKLSALQVL 1761 HSP 3 Score: 195.282 bits (495), Expect = 1.669e-49 Identity = 177/783 (22.61%), Postives = 351/783 (44.83%), Query Frame = 1
Query: 1360 KFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDL------VHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKD 3690
+F + A ESW+ + +++ + S + L+KH+ E ++ A++ L +T+ +L + ++ + + DLW L + + L +Q T E+QA I + ++YGK + V L++ H+ ++ DI R+ +L+ +A +V + F + + A + E+ F +L++ +R+ L+ S + QF+ D +E WIK+ I + D G +L V L++K + E E++S + ++ L G+ LV + I AK+ + LWE L + ++R KL L +QY + + W+ E L G + E L+RK+ ++ I +R+ L + + K D +E++Y L D+A +LLD+ ++ L ++D + +W+ EK+ + + D+E +E+L +FEVF +L E++ + ++ L+ + + + ++I + + W+ + + ++ +EL F + WI+EKI + + DL V QR+ QRD+ A+ K+D ++ D++ SAK H+ +L V + W+ LQQL + S L + F+ D +W+ ++A + + + ++ E LI + + E+ + +EE+ L S + +R N+ + W L + ++L+ + F +A Q+E LNA+E L+ +
Sbjct: 2338 QFLRDAKELESWMNEKLQIAAEASY-REATNLQQKLQKHQTFEAEVSAHKSELDAITQTGQSLMRNSPSCQETVESRLKDLADLWSLLGDLSDNKAQRLKEAIQKQTFERNVIELQAWIEEVENALASEDYGKDMRSVNNLIKRHQSLQMDIARYEDRVSELLKQAGEFV--AAEHFLKDEIADRAADVAER-------FEQLVEPATERELRLQDSLALHQFLADTQVEVDWIKDKEPIAKSEDYGRNLLGVQSLMKKMEGLESEINSHELLVQALLETGEQLVLRGHYAERDIGAKSQMLLELWEELRINAQTRNEKLQASLATHQYYDQVFEMDAWVSEKLSLVSSTDYGRDETSAETLLRKHDALQLELDANESKIRDLRSIYSELSDAGDTEFSKLEKIQDELEERYTHLRDVARDRHRRLLDSSRLFNFLREADELGAWVEEKEAIVSSDDCGRDLEHVEMLMQKFEVFTRDLVSSGERIAKLTEHAQMLLDDEHTDSEMIEQRAEVICERWDGLKERTSTRLEELDRARDLHAFRRSVDEIHAWIQEKIDALGVAENGAPDLRHVQALQRKHQGFQRDLQALGEKVDLVLRDADDL------SAKVPAHKHELIMEKQEVQKAWKKLQQLASSKQSHLLQSEGLQAFLDDYRDLMSWIETTSAQVAEETLGSTFADVETLIAQNQELQTEIDSRANSVEEFQSRADQLLGSGNPSAEDIR--NKSSHVRDTWDRLGASLRTRTQQLQHNKEIQRFKREADQLEAWLNAREHDLLSE 3102 HSP 4 Score: 187.963 bits (476), Expect = 2.739e-47 Identity = 217/985 (22.03%), Postives = 445/985 (45.18%), Query Frame = 1
Query: 1357 QKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAA-LKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDL---WKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEI-LRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLK-----SEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDK-------MLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNL 4260
Q F + A WI + ++ + +S + P L LK+H+A E +I A N G+ +I+ ++ I K+K+ L W L+ E+ L + L +V+ + A +++ G+ L V+ L + H+L+ESDI ++ A++ + Q + NS IK + + LL DKR+ +L+ + + QFI D +E W++E + ++ DLG L SV RL ++H FE EL++ + ++ L G+ L+D + + + ++QNLW+ LVD RK +L + +Y+S+ ++A+ W+++ L + G + E L+ +++ V + I+++ +A+ L+ S D + ++ +E+++ L + +L ++ ++ + + + ++++E+ + + D E L+V++ RF F+ + AE +V+NL++ LV G+ + I QD + W + D + ++ L S F D + I I+EK I ++++LG DL S QR+ + ++ +E +I+ L + + + ++A+ +E V WE L++ + L + + ++ + D +W + +AS + + S+AE+++ + + EM A E+ ++ G+ ++ E+ D+ L + E + W + L + +F +DA+Q++ ++QE L+ L V+E E + K +LS E+ L+ + GK LI + D ++N+ + +R +K R+ KL+ + + QD+ + + ++EK+Q + S + + +S L + +A E E+ A+ I+ + +G+Q + E+ ++ L W EL +A K + L
Sbjct: 960 QNFIRDADEFGGWIKEKSQIAEDESFKD--PKNLQGNLKRHKAFEAEITA---NKDGIDRINKAGKDLIRTKHFGAQKVKDKLKGLNEAWLNLVADTTEKGNKLQQAERQRQLNRAMEDVRIWMNETEAVLGLEDTGRDLAGVKFLTKKHQLLESDI---EMHATVIVDVADKAQELVSQ---GHFNSDT---IKSDSENLQSRYRSLLCLTDKRRSVLEDAFALHQFIYDIEVEMTWVREHLQQASSGDLGTSLISVQRLQKRHLAFENELTNHQTRIDTVLSSGQDLIDSCYSATDKVEERCEELQNLWDELVDMAAQRKQRLHDSFLSQKYLSEANEADSWMNDKAGLAASQDYGKDGASAETLLTRHKALQVDVAAFSTTIDELAEEARRLVQSSHFDSEKISSTQRDLEEQFCGLNTLVKTRHTRLTESKKLHEYRREVEEISAYVSEQLQTAASEDYGTDFEHLQVIQGRFGDFQRSVASYAENFRNVDNLAKMLVSEGHTDTVAIKEQQDITRSMWLHLEDQIRLRQKRLTSAEEIHRFNRDLNELISRIQEKDAAI-NLEDLGRDLASTQVLQRKHEVFECELVTLEKQIEELTVESARLQATYQGQTARSVEQHEKYVLSLWEELKRKTSRKRRKLHDAYEFYKLGNTVRDLISWCIETSRLIASDDPVHTVSDAERMMRELDEHHAEMDAREESFARVLETGEKMIEDGHFAEEEITDKLELLLSERERLYASWDTRKE-------ELSEAYYLHVFLKDAKQVDSFTSSQEAVLL----------------CAELGNSVDEVEFLLKKHENTEKLVLSQEEKLSALQVLGKELIDNQHNQSDMIRNRLSGVCDRREKLKAELDKRREKLQNSHKIMQFYQDVVESESWIMEKLQTATDESFKDPINLESKLQKHQAFESELTAHERAIDSVRDKGEQLISCGHFAASEVEVRIEALYIQWEELLEASATKGRKL 1906 HSP 5 Score: 131.724 bits (330), Expect = 3.032e-30 Identity = 137/659 (20.79%), Postives = 297/659 (45.07%), Query Frame = 1
Query: 1357 QKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFI-------AAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFL--CNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFI 3306
Q+FN++ + +S ITD ++ G + + +K + + D+ + + +++ L + + + I +N + + W +L ERR+ L +++ +V ++I A Q G+ L VE L+R H+ +E ++ I ++E+L EA R V+ R+ ++ K+ I+ + L D D+RK IL+ + L+ F+VD W+ +L M++ +L ++ + +L H+ + +++++ S + G +LV+ V + I +N ++Q LW +SRK+ L + D +++D + AE WI + + + + E L++ + + + Y +NI + + A+ L + + K I K++ L +A KL ++ +++ L D+ + SW+ EK + ++ + ++++ ++ KH + FE+E++ ++ + ++L+ N + + + +L + W+ + D+ D+K L F + + WI E + S D G+D+ SV +R +Q DI E ++ L+ Q E + +I + V + +E L + +R+ L + +H+F+
Sbjct: 1913 QQFNQEVDIADSCITDKETIVLSSDYGRDFEHCVRLQRKMKEFDQDLAVDAARVEAINVLAEKLIGQGHAGSVRIQQRQNALTERWNRLQDKASERRQKLAEACEIHAFNRNCRDVSSMINEKAAVQTSGEVGRDLPAVEALIRKHDDVERELTVIEGKMEELEGEAYRLVRSQPHMARA---------VQAKQADIIEQWERLNDLFDQRKVILEANRLLQIFLVDYRDLMSWMNDLGTRMSSGELADNVRDAEAMLGLHEERKGQMNARMDSYNATVAFGMSLVEQGHVSADVIKQNVDDLVLENTELQQLW-------QSRKLMLQQSTDLQMFLADAEKAENWIKNKQMVAQSIESRESLDNVESLLKSHINFEKSLSTYEENIRSLESSAKQFLQVKHYHAEAIRSKYLEILDKWEALKKLAASRSGKLGESKLLFQFLRDAKELESWMNEKLQIAAEASYREATNLQQ-KLQKH--QTFEAEVSAHKSELDAITQTGQSLMRNSPSCQETVESRLKDLADLWSLLGDLSDNKAQRLKEAIQKQTFERNVIELQAWIEEVENALASED-YGKDMRSVNNLIKRHQSLQMDIARYEDRVSELLKQAGEFVAAEHFLKDEIADRAADVAERFEQLVEPATERELRLQDSLALHQFL 2551 HSP 6 Score: 112.849 bits (281), Expect = 1.538e-24 Identity = 160/767 (20.86%), Postives = 328/767 (42.76%), Query Frame = 1
Query: 1249 LSTINSAWDELNTAEYGRETAL---RKEL-MRQEKLR--------NLAQKFNKKAAL-----RESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAM-IKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKS 3495
+S IN DEL + A+ RKE+ R EKL+ NLA+K + L SWI + L K+ LG ++ TV A L++H+ IE D+ A E+ + L + +L I + +V+ LW L ++R+ LD + + ++ + + + + EL++ HE +I++ +R ++L D+ R+ + + +A+ +K+ + + L S KR + L H L Q VD E +W LL+KH+ F L+++ + + KT++ ++++A++ + N + + + R+ LL ++ D D+ WI E ++ + + D + L R EI N +D I++I + L+ Q V KL + + + +L+ + KL A +L + VR W+ E + L D+ ++ L + ++ ES++ A + V + ++ LV G+ N I ++ +NL + + + + D +R L + F D + + W+RE ++ S D LG L SV + Q+R + ++ + +ID +++ G +++ + +E + + + W+ L + R L + +++ + ++ +W+ ASQ+ + + AE L+ ++ + + ++AA ++E + + ++S
Sbjct: 616 VSDINQLADELIQDGHAHSAAVKAKRKEINERWEKLQRLKVKEEENLAEKHGVELFLDVCEEMRSWIQEKDAALCKEELGKDIETVRAQLRRHQGIERDLAAVEDKVAKLQDQAKSLVVRHPRQARQIKAKEGEVISLWAILKSKANKRKGLLDEAYGQQGFLADARDLMSWSAELKESFISAEDPQDIASASELIQQHEEKFDEIQTRFERFDQL-----------DEYGRNLLATSPQAVQVKQSMAALKAEKAALSSSWAKRNDRL-HQGLDLQSSVD---EVEW----------------------LLKKHEDFVKTLTAQEEKVRSLADMAKTIIHARHQARDWVASRAESVINRRDNVKNQASDRQKALLTSQVLQNFIRDADEFGGWIKEKSQIAEDESFKDPKNLQGNLKRHKAFEAEITAN-KDGIDRINKAGKDLIRTKHFGAQKVKDKLKGLNEAWLNLVADTTEKGNKLQQAERQRQLNRAMEDVRIWMNETEAVLGLEDTGRDLAGVKFLTKKHQLLESDIEMHATVIVDVADKAQELVSQGHFNSDTIKSDSENLQSRYRSLLCLTDKRRSVLEDAFALHQFIYDIEVEMTWVREHLQQASSGD-LGTSLISVQRLQKRHLAFENELTNHQTRIDTVLSSGQDLIDSCYSATDKVEERCEELQNLWDELVDMAAQRKQRLHDSFLSQKYLSEANEADSWMNDKAGLAASQDYGKDGASAETLLTRHKALQVDVAAFSTTIDELAEEARRLVQS 1343 HSP 7 Score: 108.997 bits (271), Expect = 2.162e-23 Identity = 207/1121 (18.47%), Postives = 479/1121 (42.73%), Query Frame = 1
Query: 1345 RNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIIS-------IINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKA--MIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKR-------GKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEK 4659
R+++ N+KAA++ S +G +LP V A ++KH+ +E ++ E + + LE E Y + S + + +++ W++L +R+ L+ + + ++ ++ + + + + ++ + E +L HE + +N R++ N V F S + G+ + +IK+ + + + EL RK +L+ S + F+ DA E WIK + + + L +V+ LL+ H FE LS+ ++ + K + + E I +K +I + WEAL SR KL E +Q++ D + E W++E ++ + + + L +K+Q V ++ ++ I QSL+ S +TV +L + + L D++ ++L +A+ + +++WI E + L + D+ + L R + + ++ + ++V + + V + I + ++ + ++ + + L F D Q ++WI++K + +S D G +L V +++ ++ +I + E + L+ G++++ + +DI + ++ + WE L+ + R+ L H++ ++ + W+ + + ++S + ++ AE L+ K+++ + E+ A E ++ + I + S+ +F +L+ + + + + L D++ ++ +RL + F +A ++ + +E + D +L + ++ + E+F ++S + +A + + + L+ + + + ++ + + + ERW R +L LH + +D++ + EKI L + N + D L +AL+ + ++ ++ L ++ SA P K E+I + W +L + K +L + F + + +M W++ Q VA++ + + + ++ Q ++L + N + ++ D +LL NP A + V+ T D L L ++ ++F ++ D W+N +
Sbjct: 2026 RDVSSMINEKAAVQTSG-----------EVGRDLPAVEALIRKHDDVERELTVIEGKM-------EELEGEAYRLVRSQPHMARAVQAKQADIIEQWERLNDLFDQRKVILEANRLLQIFLVDYRDLMSWMNDLGTRMSSGELADNVRDAEAMLGLHEERKG---QMNARMDSY----NATVAFG----MSLVEQGHVSADVIKQNVDDLVLENTELQQLWQSRKLMLQQSTDLQMFLADAEKAENWIKNKQMVAQSIESRESLDNVESLLKSHINFEKSLSTYEENIRSLESSAKQFLQVKHYHAEAIRSKYLEILDKWEALKKLAASRSGKLGESKLLFQFLRDAKELESWMNEKLQIAAEASYREATNLQQKL-QKHQTFEAEVSAHKSELDAITQTGQSLMRNSPSCQETVESRLKDLADLWSLLGDLSDNKAQRLKEAIQKQTFERNVIELQAWIEEVENALASEDYGKDMRSVNNLIKRHQSLQMDIARYEDRVSELLKQAGEFVAAEHFLKDEIADRAADVAERFEQLVEPATERELRLQDSLALHQFLADTQVEVDWIKDKEPIAKSED-YGRNLLGVQSLMKKMEGLESEINSHELLVQALLETGEQLVLRGHYAERDIGAKSQMLLELWEELRINAQTRNEKLQASLATHQYYDQVFEMDAWVSEKLSLVSSTDYGRDETSAETLLRKHDALQLELDANESKIRDLRSIYSEL--SDAGDTEFSKLEKIQDELEERYTHLRDVARDRHRRLLDSSRLFNFLREADELGAWVEEKEAIVSSD---------DCGRDLEHVEMLMQKFEVFTRDLVSSGERIAKLTEHAQMLLDDEHTDSEMIEQRAEVICERWDGLKERTSTRLEELDRARDLHAFRRSVDEIHAWIQEKIDALG---VAENGAPD--LRHVQALQRKHQGFQRDLQALGEKVDLVLRDADDLSAKVPAHKHELIMEKQEVQKAWKKLQQLASSKQSHLLQSEGLQAFLDDYRDLMSWIETTSAQ-VAEETLGSTFADVETLIAQNQELQTEIDSRANSVEEFQSRAD--QLLGSGNP-SAEDIRNKSSHVRDTWDRLGASLRTRTQQLQHNKEIQRFKREADQLEAWLNAR 3095 HSP 8 Score: 90.8929 bits (224), Expect = 7.616e-18 Identity = 97/485 (20.00%), Postives = 209/485 (43.09%), Query Frame = 1
Query: 1387 ESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGY-DLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLS 2838
++W+++ + L+ G + + L+KH+A++ ++ A E + L I L + + + ++++ + + L +R L + +++ + E E+ A + A D+ G+ L VE L++ E+ D+ S +R+ KL A + D+ S + +I E+ + + L+ LD+ +++ V + WI+E +D + + G DL V L RKH+ F+ +L + ++ L + L P + + + ++Q W+ L S++ LL+ ++ D D WI+ + LG + E LI +NQ+ +++ +++E+ +++A LLG + + K + + L ++L + R ++D + +W+ ++ L + D +E +E L + + FE L + EK + N S
Sbjct: 2664 DAWVSEKLSLVSSTDYGRDETSAETLLRKHDALQLELDANESKIRDLRSIYSELSDAGDTEFSKLEKIQDELEERYTHLRDVARDRHRRLLDSSRLFNFLREADELGAWVEEKEAIVSSDDCGRDLEHVEMLMQKFEVFTRDLVSSGERIAKLTEHAQMLLD--DEHTDSEMIEQRAEVICERWDGLKERTSTRLEELDRARDLHAFRRSVDEI-------HAWIQEKIDALGVAENGAPDLRHVQALQRKHQGFQRDLQALGEKVDLVLRDADDLSAKVPAHKHELIMEKQEVQKAWKKLQQLASSKQSHLLQSEGLQAFLDDYRDLMSWIETTSAQVAEETLGSTFADVETLIAQNQELQTEIDSRANSVEEFQSRADQLLGSGNPSAEDIRNKSSHVRDTWDRLGASLRTRTQQLQHNKEIQRFKREADQLEAWLNAREHDLLSEDVGDSLEAVEELLKKQDEFEKMLLTQGEKFNSLTNTS 3139 HSP 9 Score: 83.1889 bits (204), Expect = 1.609e-15 Identity = 132/717 (18.41%), Postives = 298/717 (41.56%), Query Frame = 1
Query: 1387 ESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDN--------YLQVYTLINEFCEVQAIITGITAKQRI--DNYGKHLMEVEELLRSHELIESDIRSIN---QRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIA----------AKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLG--YSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEE 3462
SW N L Q L +++ V LKKHE + A EE + L ++ +II+ +++ D +++ RR+++ N L L N + I K +I D K ++ L+ H+ E++I + R+ K + R F Q + + N+A + ++T K L ++++++ + + D + W+ E ++ D G DL+ V L +KH++ E ++ M +VD++ QE ++ + + ++Q+ + +L+ T+ R+ L + +Q++ D + W+ E + LG + + L +++ + N++ I+ + + Q L+ YS D V ++ + ++ + +L+D+A + +++L D+ + L++++ SW+ +K + D E L R + + ++ + + + + LV + + + + I + Q +L + + +V ++ L + + ++ ++ E+++ S D G D E + Q R QR + + ++ ++ I+ Q D+ W L+ IR R L + +IHRF + L++ + + + + +++ + + L K+ E+ +E+Q+EE
Sbjct: 864 SSWAKRNDRLHQGLDLQSSVDEVEWLLKKHEDFVKTLTAQEEKVRSLADMAK-----------TIIHARHQARDWVASRAESVINRRDNVKNQASDRQKALLTSQVLQNFIRDADEFGGWIKEKSQIAEDESFKDPKNLQGNLKRHKAFEAEITANKDGIDRINKAGKDLIRTKHFGAQKVKDKLKGLNEAWLNLVADTTEKG--NKLQQAERQRQLNR-------AMEDVRI---WMNETEAVLGLEDTGRDLAGVKFLTKKHQLLESDIE----------MHATVIVDVADKAQELVSQGHFNSDTIKSDSENLQSRYRSLLCLTDKRRSVLEDAFALHQFIYDIEVEMTWVREHLQQASSGDLGTSLISVQRLQKRHLAFENELTNHQTRIDTVLSSGQDLIDSCYSATD--KVEERCEELQNLWDELVDMAAQRKQRLHDSFLSQKYLSEANEADSWMNDKAGLAASQDYGKDGASAETLLTRHKALQVDVAAFSTTIDELAEEARRLVQSSHFDSEKISSTQRDLEEQFCGLNTLVKTRHTRLTESKKLHEYRREVEEISAYVSEQLQTAASED-YGTDFEHLQVIQGRFGDFQRSVASYAENFRNVDNLAKMLVSEGHTDTVAIKEQQDITRSMWLHLEDQIRLRQKRLTSAEEIHRFNRDLNELISRIQEKDAAINLEDLGRDLASTQVLQRKHEVFECELVTLEKQIEE 1544 HSP 10 Score: 70.4774 bits (171), Expect = 1.007e-11 Identity = 179/906 (19.76%), Postives = 368/906 (40.62%), Query Frame = 1
Query: 1573 ISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISE-ANRYVQFCDQDFRSN--INSGN--KAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNM----EIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQI----------IVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEM----------AAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESI----NQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQV-LNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEII 4188
I+I NT N+ L++T RR L ++ Y +E CE + + N + +E S +++ I+++ Q+LE+ +E A + + D + ++ I G+ A +K KR + + +L K +E L H V F+ WI+E + +LG D+ +V LR+H+ E +L++ + + K+LV P I AK ++ +LW L RK L E +++D D W E K F + ++ Q++ E+++ + + ++I QT ++ D++++ ++LL A Q + + SW + ++E+E L + E F LT + EKV + ++++ ++ + HQ ++N +DN+ N ++ LL+ NF D + WI+EK ++ E DE +D +++ +R + +I A + ID + G +++R A+ ++ +L +++ W L ++ + L + + ++D W+ + + + ++ + + L K+ ++ A Q+L D +KS+ + LQ+R S+ ++ +L D F D IE + ++L Q+ + TS L+S+ + + F +++ + + + VL G+ LI D+++ +C+ L W + A RK +L + L + L + ++ D + +K + ++ + S ++ L + KAL+ ++ A+ I+EL + ++ HF E I
Sbjct: 536 ITITNTYNR-------LIETSEMRRLSLQKAIKYYHFCHE-CEDMDLW--------MSNKERQFKSIE----SQNTLDA-IQTVRQKLERFATEIATKCSRVSDINQLADELIQDGHAHSAAVKAKRKEINERWEKLQRLKVKEEENLAEKHGVELFLDVCEEMRSWIQEKDAALCKEELGKDIETVRAQLRRHQGIERDLAAVEDKVAKLQDQAKSLVVRHPRQARQIKAKEGEVISLWAILKSKANKRKGLLDEAYGQQGFLADARDLMSWSAELKESF--------------ISAEDPQDIASASELIQQHEEKFDEI---------------QTRFERFDQLDEYGRNLL--ATSPQAVQVKQSMAALKAEKAALSSSWAKRNDRLHQGLDLQSSVDEVEWLLKKHEDFVKTLTAQEEKVRSLADMAKTII---HARHQARDWVASRAESVINRRDNVKNQ-------ASDRQKALLTSQVLQNFIRDADEFGGWIKEKSQIAE--DESFKDPKNLQGNLKRHKAFEAEITANKDGIDRINKAGKDLIRTKHFGAQKVKDKLKGLNEAWLNLVADTTEKGNKLQQAERQRQLNRAMEDVRIWMNETEAVLGLEDTGRDLAGVKFLTKKHQLLESDIEMHATVIVDVADKAQELVSQGHFNSDTIKSDSEN-----LQSRYRSLLCLTDKRRSVLED-----------AFALHQFIYD---IEVEMTWVREHLQ---QASSGDLGTS---LISVQRLQKRHLAFENELTNHQTRIDTVLSSGQDLIDSCYSATDKVEERCEELQNLWDELVDMAAQRKQRLHDSFLSQKYLSEANEADSWMNDKAGLAASQDYGKDGASAETLLTRHKALQVDVAAFSTTIDELAEEARRL-VQSSHFDSEKI 1351 HSP 11 Score: 67.781 bits (164), Expect = 6.538e-11 Identity = 153/805 (19.01%), Postives = 311/805 (38.63%), Query Frame = 1
Query: 4069 LAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTM---DGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKI-DLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----------PDEYKG-------IVKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNT 6417
L + + +E ++ A + +L + K P ++I + S WA L ++ L ++ F + +M W ++ ++ ++P S I +K D ++ + + + L ++ L +P QVK +M L S + N ++ LQ DE++W+ +K D ++ + Q E KV SL A+ +I H R V + R+N+ + Q L +Q F+ D E WI EK + + KD + ++ +++ + E EI I+ K+ L D+ KG +V D + N L+ AE++ +++ + +++ W+ E + +D+G+DL L + + S+ + V+ A+K EL+ H + +I + + + LL L D R +L+ A+ LH++ D + + ++E DLG SV LQ++ FE +L + I+ ++ L+ C + ++ +EL + + L + RK + +LS E W+ + + +D + E LL H++L++++ + R L+++ H S +I S +++ ++ L L+ +++++ R+ A+V Q +E+ G + + +F FQ++ + E F + L M + +T
Sbjct: 705 LRRHQGIERDLAAVEDKVAKLQDQAKSLVVRHPRQARQIKAKEGEVISLWAILKSKANKRKGLLDEAYGQQGFLADARDLMSWSAELKESFISAEDPQDIASASELIQQHEEKFDE----IQTRFERFDQLDEYGRNLLATSPQA--------VQVKQSMAALKAEKAALSSSWAKRNDRLHQGLDLQSSVDEVEWLLKKHEDFVKTLTAQEE---------------------------KVRSLADMAKTIIHARHQARDWVASRAESVINRRDNVKNQASDRQKALLTSQVLQNFIRDADEFGGWIKEK--SQIAEDESFKDPKNLQGNLKRHKAFEAEITANKDGIDRINKAGKDLIRTKHFGAQKVKDKLKGLNEAWLNLVADTTEKGNKLQ--QAERQRQLNRAM---------EDVRIWMNETEAVLGLEDTGRDLAGVKFLTKKHQLLESDIEMHATVIVDVADK-AQELVSQGHFNSDTIKSDSENLQSRYRSLLCLTDKRRSVLEDAFALHQFIYDIEVEMTWVREHLQQAS-SGDLGTSLISVQRLQKRHLAFENELTNHQTRIDTVLSSGQDLID-SCYSATDKVEERCEELQNLWDELVDMAAQRKQRLHDSFLSQKYLSEANEADSWMNDKAGLAASQDYGKDGASAETLLTRHKALQVDVAAFSTTIDELAEEARRLVQSSHFDSEKISSTQRDLEEQFCGLNTLVKTRHTRLTESKKLHEYRREVEEISAYVSEQLQTAASEDYGTDFEHLQVIQGRFGDFQRSVASYAENFRNVDNLAKMLVSEGHTDT 1454 HSP 12 Score: 67.0106 bits (162), Expect = 1.226e-10 Identity = 58/292 (19.86%), Postives = 123/292 (42.12%), Query Frame = 1
Query: 2242 IAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEW---IREKIKLIESMDELGEDLESVMQRQRRINHMQ 3108
+A + I N + L++++E R++ L + + YY + +C+D + W+ +R F + + + + +K ++ + + I A L+ V K I ++++ L + K +E L + V L+ + +RSWI EK LC DIE + R + E +L +KV + + +++LVV + I + + + W + + ++ L Y F D + + W ++E E ++ E + Q + + + +Q
Sbjct: 531 VAVRQITITNTYNRLIETSEMRRLSLQKAIKYYHFCHECEDMDLWMSNKERQFKSIESQNTLDAIQTVRQKLERFATEIATKCSRVSDINQLADELIQDGHAHSAAVKAKRKEINERWEKLQRLKVKEEENLAEKHGVELFLDVCEEMRSWIQEKDAALCKEELGKDIETVRAQLRRHQGIERDLAAVEDKVAKLQDQAKSLVVRHPRQARQIKAKEGEVISLWAILKSKANKRKGLLDEAYGQQGFLADARDLMSWSAELKESFISAEDPQDIASASELIQQHEEKFDEIQ 822
BLAST of Spectrin beta chain vs. Ensembl Medaka
Match: sptbn2 (spectrin beta chain, non-erythrocytic 1 [Source:NCBI gene;Acc:101155789]) HSP 1 Score: 1289.25 bits (3335), Expect = 0.000e+0 Identity = 802/2369 (33.85%), Postives = 1325/2369 (55.93%), Query Frame = 1
Query: 184 NVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKII----AEQFLQDCDDEIDWMNEKIDLIRN--RSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSID-SSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPS-NMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNP-STTQSHPNLSSS 7242
N ++++FERSRIKALADERE VQKKTFTKW+NS L VT +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR GL F A++HKHRPD+I+F + R++ NL AF++AE LG+ LLDPEDVNV PDE+S+ITYVA+YYHYF+ +KA +V KR+ K+L+ +E +Q+I Y++L S+LL+WI TI LN RQ +NS+ +Q Q+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KAA+RE+W+++N L+ + + G +L V AA +KHEAIETDI AY E ++ + ++ LE E Y+D+ I+ ++ VL LW+ L + L RRE L + + L E + + + + + GKHL +V +LL+ H L+E+DI + +R++ + + A + + +Q ++ ++ EK + + EL R+E L+ S +WQF+ D E WI+E I+ + D G DL+S LL KH+ F E++++ + L N + G+ L++ G + + DI+ W L ++T+ R+ L E + +Q+ +D +D E WI E R + LG T+ L RK ++ E ++++R I + QAQ+ L + V H V +L IE+ Y++L ++ ++ L AL++Y++ +++D+ W+ EK+++L +E+LEV++ RFE E E+ +V HVN+++E L+ + N I +D LNN W + + K+ L S + N+ ++C + W++EK K+IES LG DL VM QR++ M+RD+ AI+ K+D L ++ ++ + A++I+ +L + + WE L ++ R+ +L + + F++ L+DF +WL + QT +AS++IP S EAE L+ ++ S ++E+ ++ E+ +G++ + + D Q + L R+++++ W L + E + L + F DA+Q E LN+QE L + +NL + E + ++E F+ + E+ + V+ G+ LI ++N D++Q K ++ ER KN A+ KLK+ L LQD +L + EK+ ++S ++ S + +A E+ + + +++++K G+ A+ P K + L++L W E+ K Q L NR +LF +S ++ WL NIE Q+ +DD +TS+ LKK ++E ++K +++L+ + L Q++ + +++ Q + D S L+ L + QK++ A QF +D +DEI W+ E++ L + K + T+ L++ ++++++ EI+ ++D +++ + + ++AL+ + + +L+ + L E + L Q+F D +E +W+ E+EL +M +KD+Q +++K Q LE +++Y I + S + P+ + ++ V+ + LK + E++ + + ++E WI ER +A S + G+D + ++LRD+F F+ +T+ IG +V+ N D+LI+ HP S++ WKD +NE WADLLELIDTR Q+L ++++LHR++ D+ +L ++EK+ ++ DLG+D +V L R+ + E D+ L +N + L Y +K + + + A+ +L++ + R+L + + FL+ VR+L+ W++ V +Q++ PRDVS EL++ NH+ +K E+D++ ++F+ +++G L+ H + EI+ K ++ ++RD + +KW + +++L +++EV Q+ RDA+ AE+W+ QE + LG +DE +LLK+ F+K EE+F QL+RLTT+E + + + + Q V E+ Q E + H R S+D ++L+QD + + S+ + S V + KQ +R S +++ P + +++ L AS + ++G L RK + E+ N+KA+ R+WH++Y L + + FFKD + Y EMP L E V A DY KR VF++R NG EYLFQ +M W+ +I Q +P S + P +S S
Sbjct: 37 NSSARLFERSRIKALADEREAVQKKTFTKWVNSHLSRVTCRIGDLYTDLRDGRMLIRLLEVLSGEQLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGLAFNAIVHKHRPDVIEFDNLKRSNAHYNLQNAFNVAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDYAIEADQLIDKYETLASELLQWIEQTIGTLNDRQLANSLNAVQNQLQAFNSYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYVPKEGKLISDINKAWERLEKAEHERELALRNELIRQEKLEMLAARFDRKAAMRETWLSENQRLVSQDNFGTDLGAVEAATRKHEAIETDINAYLERVVAVEDVAKELEAEGYHDVRRILARRDNVLRLWEYLKELLAARRERLTAHRDLQRLFQEMRYITDWMKDEQGRLQSQDTGKHLHDVLDLLQKHNLVEADISAQAERIKGVQAAAKPFSSY-EQAYK----PCEPGLVGEKVERLGQAYEELGQLASARRERLEDSRRLWQFLWDLGEEAAWIREQEQILASGDCGRDLTSALHLLSKHEAFRDEMAARFMPLNNSIAAGEALINEGHFGASEVTERIQDIRAQWAHLEETTKLREQSLKEAVALHQFQTDANDMEAWIMETLRQLSSQELGHDEFSTQTLARKQREIDEEIQSHRPLINTLHEQAQA-LPQAYVSHPQVDGRLPAIEQSYKELESLSATRRQALDGALSLYQMFSEADACLLWVEEKEQWLDGMEIPTKLEDLEVVQQRFESLEPEMNNLGARVTHVNDVAEFLLDSDNCRKDQIHQTRDQLNNRWAEFEQLAGQKKQALESALNIQNYHLECNEIKSWMKEKTKVIESTQSLGNDLAGVMALQRKLTGMERDLEAIQGKLDDLKSEAGKLASEHPDQAEEIQGRLAEIQEVWEELNATMKRREESLGEASKLQGFLRDLNDFQSWLSRTQTAVASEDIPTSLPEAENLLTQHESIKNELDNYKEDYEKMRAVGEEVTQGQTDA-QHMFLAQRLQALDTGWHELRRMWENRHSLLAQGFDFQGFMRDAKQAEAFLNSQEYVL---------HHTEMPTNLQAAEEAIRKHEDFLTTTEASEEKINSVVDSGRRLINDSNANSDKIQEKVDSIQERHNKNKEMAKELLTKLKDNRELQHFLQDGQELTLWINEKMLTAQDMSYDEARNLHSKWQKHQAFMAELASNKDWLDKIDKEGQALVAEKPELKPVVQQILEDLQHQWEEVEGTTRTKAQCLFDANRAELFTQSCSALGSWLNNIESQLHSDDYG----KDLTSVNILLKKQQMLEHQMEVREKEVQSLQAQALALSQED----AGLTEIDGQQRQVTDNFS-NLQQPLRLRKQKLLASKEAHQFNRDLEDEILWVTERMPLATSTEHGKDLSTVQLLIK------KNQTLQKEIQGHQPRIDDILKRGETQSQVDGERQALLEERLAELRDLWDQLISETDNRNTRLLEARRAQQFYADAAEAEAWMGEQELHMMS-EEKAKDEQSALVMVKKHQILEQTLEDYAQTIHQLANSSRLMVTNEHPESERITLRQAQVDKLYAGLKDLAEERRGRLQERLRLTQLKREVDDLEQWIAEREMVAGSHELGQDYEHVSMLRDKFREFARDTSTIGQERVDGVNALADDLIESGHPENASVAEWKDGLNEAWADLLELIDTRTQMLGASYELHRFHQDAMEVLGRVKEKREALPA--DLGRDLNTVKHLHRQHQTLENDIQALSWQVNQVQDDAARLQKAYAGEKADDIHRSEHAVSSAWEALQEACQSRRLLLQDTVEKFRFLNAVRDLMLWMDGVNLQIDAHDSPRDVSSAELVIGNHQDIKSEIDTRADSFTASIDMGNALINKSHYAADEIQEKLAQLQERRDEINKKWQDKMNYLQIVLEVLQFGRDASVAESWLAGQEPLVRAAELGTNVDEVESLLKRHEAFEKLATAWEERFVQLERLTTLEEQELQRRREEEERARRPPTPPQ-----VEEVTQSKAET--------------QAHDSEAR--TSLDQTTLNQDVSVNGVHSDNDTSQSLSLSLSVGKKSEPKRVFKPKQPERGSESESVNGPGRDSGLASSRLEASATLPGRGGADSDAECVEGMLCRKQEMESHNKKAATRSWHNVYCTLKKGGLHFFKDNKSVSSGIT--YHGEMPFSLEEAVCEVALDYKKRKHVFKLRNENGKEYLFQAKDEAEMNSWIQSIRRFITTRSQDSPGAPRALSRAMTMPPISPS 2348
BLAST of Spectrin beta chain vs. Ensembl Medaka
Match: sptbn1 (spectrin beta chain, non-erythrocytic 1-like [Source:NCBI gene;Acc:101164035]) HSP 1 Score: 1284.24 bits (3322), Expect = 0.000e+0 Identity = 799/2373 (33.67%), Postives = 1319/2373 (55.58%), Query Frame = 1
Query: 211 SRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIR--NRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PD-EYKGIVKD-VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSI--DSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAI-NSASRPMRQVN---PSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRF 7284
R K L DERE VQKKTFTKW+NS L V+ +I DLY+DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + +SAKDALLLWCQMKTAGYP+VNI+NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+SVITYV +YYHYF+ +KA V KR+ K+L+ +E E +I+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +L V AA KKHEAIETDI AYEE + + +S LE E Y+DI I K+ VL LW+ LL+ L RR+ L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R+ + AN+Y D ++ + +I+++ + EL +R+ L+ S +W+F + + EE WI+E I+++ + G DL+ RLL + + E E+S + L++ + EG+ +V + G + I + D+Q W L + +L E L +Q+ +D DD + W + R+ G T+ L+RK++ V +YR I+ + QA +L + ++V +L IE++Y+++ ++ +E L DAL +++ +++++ + WI EK+++L + +E+LEV++HRF+ E E+ +A +V VN + L+ G+P+ I QD LNN W D++D K++ L S N+ +DC +T WI+EK K+IES ELG DL V+ QR++ M+RD+ AIE K+ L + + + AK I +L + WE ++ ++ R+ +L + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ +++ ++E+ E+ ++ +G D + Q Q++ LQ R+++++ W L+ + E ++ L + +F D +Q E LN QE Y++ + L + + E F+ M ++E + V++ G+ L + N+ ++++ K ++D+R KKN AA +LK+ L + LQ+ +L + EK+ +++ ++ S + +A E+ + + + ++ K G ++ P + + + L L+S W EL + K Q L N+ +LF +S + KWL +EGQI ++D +TS+ LKK ++E +++ + L+ + L Q+ D + + V+ L PL + ++ QF +D +DEI W E++ + + ++T+ L++ ++++++ E++ ++D +++ +Q ++ + + + +L++ + L EE + L Q++ D +E +W+SE+EL +M +KD+Q +++K Q +E +++Y + + K+ L P+ E G+ + V+ + LK + E++ ++ + ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N DELI H A +++ WKD +NE WADLLELIDTR Q+L ++++LH++Y D + +L I +K+ + ++G+D +V LQR +FE+D+ L + + + L Y DK + +K E+++A+R L + + R+ L+ + F SMVR+LL W+++V +E + PRDVS +ELL+ NH+ +K E+D++ ++FS C+ LG+ LL KH + EIK K ++TDKR + KW + + L L++EV+Q++RDA AEAW++ QE YL++ +G ++DE L+K+ F+K+ EE+F + + ++ E ++ P P + HQ+ +++ S+ + L D + TG ++ + S++ P P P P+ K H+ S S P ++ P V M+G L+RKH+WE N+KASNR+WH++Y ++ M+FFKD + + Y ++ P+ L + A DY K+ VF++R +G EYLFQ +M+ W+ I N+A+ + P Q+ P + +L ++ K KRF
Sbjct: 14 GRFKQLQDEREAVQKKTFTKWVNSHLSRVSCRITDLYLDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKERRSAKDALLLWCQMKTAGYPNVNIQNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTRLLDPEDISVDHPDEKSVITYVVTYYHYFSKMKALKVEGKRIGKVLDNAIETENLIEKYESLASALLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRMELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGLDLQAVEAATKKHEAIETDIAAYEERVQAVVAVSKELELECYHDIKRIAARKDNVLRLWEYLLELLKARRQRLEMNLGLQRVFQEMLYIMDWMDEMKMLLLSQDYGKHLLGVEDLLQKHALVEADIAIQADRVRAVSCNANKY-SVTDGGYKP----CDPRVIQDRVAHLEFCYQELTQLAAERRARLEDSRRLWKFFWEMAEEEGWIREKEQILSSLEQGRDLTGAVRLLSQQRALEDEMSGRAGHLQHTITEGRAMVQVGHNGSDKILERIGDLQAQWAELEQHAAVTRRRLEEALALHQFQADADDVDAWTLDALRIVSSGETGHNEFSTQALVRKHKDAAAEVASYRPVIDSLHEQAATL---PKEEAESVRGRLAGIEERYKEVAELTKLRKEALQDALARHKMFSEANACQVWIEEKEQWLNATEIPEKLEDLEVVQHRFDSLEPEMNNQASRVAVVNQIGRQLMHAGSPSDDIKAQ-QDKLNNRWGLFRDLLDLKKESLNSALGVQNYHLDCNETKSWIKEKTKVIESTQELGNDLMGVLALQRKLTGMERDLVAIEDKLGDLRGEAQRLAEEHPDQAKAITGRLAEITAVWEEMKNTLKRREESLGEARKLQQFLRDLDDFQSWLSRTQTAVASEDMPNTLAEAEKLMAQHDGIKNEILNYEEDYQKMRDMG-DMVTRGQTDAQYMFLQQRLQALDTGWNELHKMWENRQNLLSQSHAYQLFLRDTKQAEAFLNNQE-YVLAHAEM--------PPTLEGAEAAIKKQEDFMTTMDANEDKINGVMEAGRRLASDGNINAEKIKEKVASIDDRHKKNREAAVELLMRLKDNRDLQKFLQECQELSLWISEKMLTAQDMTYDEARNLHSKWLKHQAFMAELQSNKEWLNKIEKDGTLLVSEKPETEVVVKEKLTALHSMWEELESTTQTKAQCLFDANKTELFTQSCTDLDKWLGGLEGQIQSEDYG----KDLTSVNILLKKQQMLENQVEVRQREVVELQSQVKALGQEAKD-TDEVDGRRQGVEKKFQELLEPLRHRRNLLVASREGHQFNRDVEDEILWAQERMPVATSTDHGHNLQTVQLLMK------KNQTLEKELQGHQPRIDDILERSQSLLRDQTSGTEGIHRRLAELQELWDRLREEGRRRHARLQEAHKAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSAITMLKKHQIMEQAVEDYAEVVHQLSKTSRGLVANEHPESERIGMRQSQVDKLYAGLKDLSEERRGKLEERLRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDGVNHLADELINAGHGDAATVAEWKDGLNEAWADLLELIDTRTQILAASFELHKFYHDGKEILARIADKQKKLP--EEMGRDQNTVETLQRMHTSFERDVQALGAQVRQLQEDAVRLQSSYAGDKADDIQRKDGEVLEAWRILLEACDSRRSRLLDTGERFRFFSMVRDLLLWMDDVIRLIEAQENPRDVSSVELLMNNHQGIKAEIDARNDSFSTCVELGKALLARKHYAAAEIKEKLLQLTDKRKEMIDKWEDRWEWLRLILEVHQFSRDAGVAEAWLLGQEPYLSSREVGQSVDEVEKLIKRHEAFEKSAATWEERF----------------------------SALERLTTLELLEVRRQQEEMERRRRPP---SPEQLHQEEVQQEKSVVMQNGLPSDEDSPWTGL-----EGGGLVNGLVERSSMEPSPA------PSPTMTKKNKHSQS--------STLPLKSQDSP---VQMEGLLHRKHEWEGHNKKASNRSWHNVYCVVCHQEMSFFKDSKAAAQGAA--YHNQPPVSLKDATCDVASDYKKKKYVFKLRVADGNEYLFQAKDEEEMSSWIQVILNAAASELTDTQSSFPGTPVSGRAQTLP-ATITLTTESSPGKKEKRF 2297
BLAST of Spectrin beta chain vs. Ensembl Medaka
Match: SPTBN1 (spectrin beta chain, non-erythrocytic 1 [Source:NCBI gene;Acc:101159770]) HSP 1 Score: 1281.93 bits (3316), Expect = 0.000e+0 Identity = 761/2095 (36.32%), Postives = 1248/2095 (59.57%), Query Frame = 1
Query: 160 DEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIK-LIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLS--IANQKIIAEQFLQDCDDEIDWMNEKIDLI--RNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PD-EYKGIVKD-VEDNFNSLKIICAEKKTEISLFVIYCDTYELYQ------NIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTM 6390
D D+ N ++++FERSRIKALADERE VQKKTFTKW+NS L V+ +I DLY+DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL Q+VHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR G+ F ALIHKHRPDLIDF +++ NL AF++AE LG+ LLDPED++V PDE+S+ITYV +YYHYF+ +KA V KR+ K+L+ +E E+MI+ Y+SL S LLEWI TI +LN R+F+NS+ G+QQQ+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA++F++KAA+RE+W+++N L+ + + G +L V AA KKHEAIETDI AYEE + + ++ LE E Y+DI I K+ V LW+ LL+ L RR L+ L + + E + + + +YGKHL+ VE+LL+ H L+E+DI R+ + S A R+ + + +I+++ + EL+ +R+ L+ S +W+F + + EE WI+E I+++ D G DL+ RLL +HK FE E+S + L+ + +G+ LV + G + I + DIQ W L T RK +L E +++Q+ +D DD + W+ + R+ +G T+ L++K++ E +++YR IE + +Q+++L + + V +L IE++Y+++ ++ ++ L DAL +Y++L+++ + WI EK+++L + + +E+LEV++HRFE E E+ +A +V VN ++ L+ G+P+ + I QD LN W++ D+VD K++ L+S N+ ++C +T WI+EK K LIES ELG DL VM QR++ M+RD+ AIE K+ L + + + + ++ I+ +L + W+ ++ +++R+ +L + + +F++ LDDF +WL + QT +AS+++P + +EAEKL+ ++ + ++E+ E+ ++ +G+ + + D Q + L+ R+++++ W L+ + E ++ L + +F D +Q E LN QE L + L + + + E F+ M ++E+ ++ V+ G+ L+ + N+ +R+Q K ++D+R KKN AA + +LK+ L + LQD +L+ + EK+ +++ ++ S + +A E+ + + +++++K G+ + P + + + L +L + W EL + K + L N+ +LF +S + KWL +EGQ+ +DD +TS+ LKK ++E ++K ++ LK S+ L+Q+ D + + + V+ L PL+ + +A+++I QF +D +DEI W+ E++ L + ++T+ L++ ++++++ EI+ + D + + +Q ++ E L+ + +L+ E + +E EK LS Q++ D +E +W+SE+EL +M +KD+Q +++K Q LE +++Y + + + L PD E G+ + V+ + LK + E++ ++ + + L+Q ++E WI ER +A S + G+D + T+L++RF F+ +T IG +V+ N+ DELI H A +I+ WKD +NE WADLLELIDTR Q+L ++++LH++Y D++ +L I +K + +LG+D +V LQR FE D+ L + + + L Y DK + K+ E+++A+++L +E R+ ++ D F SMVR+L+ W+E+V +E + KPRDVS +ELL+ NH+ +K E+D++ ++F+ C+ LG+ LL KH S EIK K ++TDKR + KW + + L L++EV+Q++RDA AEAW++ QE YL++ +G ++DE L+K+ F+K+ EE+F L+RLTT+
Sbjct: 26 DADDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLSRVSCRITDLYMDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALKVEGKRIGKVLDHAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYTPREGKLISDINKAWERLEKAEHERELALRTELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLQAVEAATKKHEAIETDIAAYEERVQAVVSVAKELEAESYHDIKRITARKDNVNRLWEYLLELLKARRHRLEQNLGLQRVFQEMLYIMDWMDEMKMLLLSQDYGKHLLGVEDLLQKHALVEADIAIQADRVRNVNSNAQRFASDTE-----GYKPCDPQIIRDRVAHLEFCYQELIQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEQILSSEDYGKDLTGALRLLSQHKAFEDEMSGRAAHLQQTIKQGEDLVADNHFGADKIRERIRDIQEQWATLERLTAVRKSRLQEACNHHQFQADADDIDTWMLDVLRIVSSVDVGHDEFSTQALVKKHKDVAEEIDSYRPVIEALHDQSRTLPPEK-ANSEEVKSRLAGIEERYKEVAELTRLRKQALQDALALYKMLSEASACELWIDEKEQWLNSMDIPEKLEDLEVVQHRFESLEPEMNSQASRVAVVNQVARQLIHCGHPSEKEIKAQQDKLNTRWSQFRDLVDQKKESLVSALGVQNYHLECNETKSWIKEKNKVLIESTQELGNDLAGVMALQRKLTGMERDLVAIEDKMGDLGKEAERLASEHPEQSEAIKGRLAEITGVWQEMKDGLKNREESLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLAEAEKLLAQHENIKNEIRNYEEDYQKMRDMGEMVTQGQTDA-QHMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQLFLRDTKQAEAFLNNQEYVLA---------HTEMPTTLEAAEAAIKKQEDFMTTMDANEEKISNVVDTGRRLVADGNVSSERIQEKVDSIDQRHKKNRQAASDLLMRLKDNRDLQKFLQDCQELNLWINEKMLTAQDMTYDEARNLHSKWLKHQAFMAELQSNKEWLDKISKDGQTLMTEKPETEGVVKEKLASLKTMWEELESTTQTKAKCLFDANKAELFTQSCADLDKWLNGLEGQLQSDD----FGKDLTSVNILLKKQQMLESQVEVRQKEVDELKGQSQALRQEGKD-SDEVDGQRIIVEKKFQTLQEPLKKRRDKLMASREI--HQFNRDVEDEILWVEERMPLATSTDHGHNLQTVQLLIK------KNQTLQKEIQGHQPRYDDIFERSQHVLREGSPTAELIRQRLAELQSLWEQIKKETEKRHTRLSEAHEAQQYYFDAAEAEAWMSEQELYMMSEE-KAKDEQSAVAMLKKHQILEQAVEDYADTVHQLSSTSRGLVAAGHPDSERIGMRQSQVDKLYAGLKDLSEERRGKLD------ERFRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDGVNRLADELINSGHGDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEVLNRILDKHKKLP--EELGRDQNTVEALQRMHTAFEHDIQALGTQVRQLQDDAVRLQSAYAGDKADDIQKREGEVLEAWKNLLAAVEGRRAKLVDTGDKFRFFSMVRDLMLWMEDVIRLIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKALLARKHYASEEIKEKLLQLTDKRKEMIDKWEDRWEWLRLVLEVHQFSRDAGVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWEERFSALERLTTV 2082
BLAST of Spectrin beta chain vs. Ensembl Medaka
Match: sptbn2 (spectrin beta chain, non-erythrocytic 1 [Source:NCBI gene;Acc:101155789]) HSP 1 Score: 1280.77 bits (3313), Expect = 0.000e+0 Identity = 794/2330 (34.08%), Postives = 1311/2330 (56.27%), Query Frame = 1
Query: 184 NVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKII----AEQFLQDCDDEIDWMNEKIDLIRN--RSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSID-SSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPS-NMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVV 7128
N ++++FERSRIKALADERE VQKKTFTKW+NS L VT +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR GL F A++HKHRPD+I+F + R++ NL AF++AE LG+ LLDPEDVNV PDE+S+ITYVA+YYHYF+ +KA +V KR+ K+L+ +E +Q+I Y++L S+LL+WI TI LN RQ +NS+ +Q Q+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KAA+RE+W+++N L+ + + G +L V AA +KHEAIETDI AY E ++ + ++ LE E Y+D+ I+ ++ VL LW+ L + L RRE L + + L E + + + + + GKHL +V +LL+ H L+E+DI + +R++ + + A + + +Q ++ ++ EK + + EL R+E L+ S +WQF+ D E WI+E I+ + D G DL+S LL KH+ F E++++ + L N + G+ L++ G + + DI+ W L ++T+ R+ L E + +Q+ +D +D E WI E R + LG T+ L RK ++ E ++++R I + QAQ+ L + V H V +L IE+ Y++L ++ ++ L AL++Y++ +++D+ W+ EK+++L +E+LEV++ RFE E E+ +V HVN+++E L+ + N I +D LNN W + + K+ L S + N+ ++C + W++EK K+IES LG DL VM QR++ M+RD+ AI+ K+D L ++ ++ + A++I+ +L + + WE L ++ R+ +L + + F++ L+DF +WL + QT +AS++IP S EAE L+ ++ S ++E+ ++ E+ +G++ + + D Q + L R+++++ W L + E + L + F DA+Q E LN+QE L + +NL + E + ++E F+ + E+ + V+ G+ LI ++N D++Q K ++ ER KN A+ KLK+ L LQD +L + EK+ ++S ++ S + +A E+ + + +++++K G+ A+ P K + L++L W E+ K Q L NR +LF +S ++ WL NIE Q+ +DD +TS+ LKK ++E ++K +++L+ + L Q++ + +++ Q + D S L+ L + QK++ A QF +D +DEI W+ E++ L + K + T+ L++ ++++++ EI+ ++D +++ + + ++AL+ + + +L+ + L E + L Q+F D +E +W+ E+EL +M +KD+Q +++K Q LE +++Y I + S + P+ + ++ V+ + LK + E++ + + ++E WI ER +A S + G+D + ++LRD+F F+ +T+ IG +V+ N D+LI+ HP S++ WKD +NE WADLLELIDTR Q+L ++++LHR++ D+ +L ++EK+ ++ DLG+D +V L R+ + E D+ L +N + L Y +K + + + A+ +L++ + R+L + + FL+ VR+L+ W++ V +Q++ PRDVS EL++ NH+ +K E+D++ ++F+ +++G L+ H + EI+ K ++ ++RD + +KW + +++L +++EV Q+ RDA+ AE+W+ QE + LG +DE +LLK+ F+K EE+F QL+RLTT+E + + + + Q V E+ Q E + H R S+D ++L+QD + + S+ + S V + KQ +R S +++ P + +++ L AS + ++G L RK + E+ N+KA+ R+WH++Y L + + FFKD + Y EMP L E V A DY KR VF++R NG EYLFQ V
Sbjct: 37 NSSARLFERSRIKALADEREAVQKKTFTKWVNSHLSRVTCRIGDLYTDLRDGRMLIRLLEVLSGEQLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGLAFNAIVHKHRPDVIEFDNLKRSNAHYNLQNAFNVAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDYAIEADQLIDKYETLASELLQWIEQTIGTLNDRQLANSLNAVQNQLQAFNSYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYVPKEGKLISDINKAWERLEKAEHERELALRNELIRQEKLEMLAARFDRKAAMRETWLSENQRLVSQDNFGTDLGAVEAATRKHEAIETDINAYLERVVAVEDVAKELEAEGYHDVRRILARRDNVLRLWEYLKELLAARRERLTAHRDLQRLFQEMRYITDWMKDEQGRLQSQDTGKHLHDVLDLLQKHNLVEADISAQAERIKGVQAAAKPFSSY-EQAYK----PCEPGLVGEKVERLGQAYEELGQLASARRERLEDSRRLWQFLWDLGEEAAWIREQEQILASGDCGRDLTSALHLLSKHEAFRDEMAARFMPLNNSIAAGEALINEGHFGASEVTERIQDIRAQWAHLEETTKLREQSLKEAVALHQFQTDANDMEAWIMETLRQLSSQELGHDEFSTQTLARKQREIDEEIQSHRPLINTLHEQAQA-LPQAYVSHPQVDGRLPAIEQSYKELESLSATRRQALDGALSLYQMFSEADACLLWVEEKEQWLDGMEIPTKLEDLEVVQQRFESLEPEMNNLGARVTHVNDVAEFLLDSDNCRKDQIHQTRDQLNNRWAEFEQLAGQKKQALESALNIQNYHLECNEIKSWMKEKTKVIESTQSLGNDLAGVMALQRKLTGMERDLEAIQGKLDDLKSEAGKLASEHPDQAEEIQGRLAEIQEVWEELNATMKRREESLGEASKLQGFLRDLNDFQSWLSRTQTAVASEDIPTSLPEAENLLTQHESIKNELDNYKEDYEKMRAVGEEVTQGQTDA-QHMFLAQRLQALDTGWHELRRMWENRHSLLAQGFDFQGFMRDAKQAEAFLNSQEYVL---------HHTEMPTNLQAAEEAIRKHEDFLTTTEASEEKINSVVDSGRRLINDSNANSDKIQEKVDSIQERHNKNKEMAKELLTKLKDNRELQHFLQDGQELTLWINEKMLTAQDMSYDEARNLHSKWQKHQAFMAELASNKDWLDKIDKEGQALVAEKPELKPVVQQILEDLQHQWEEVEGTTRTKAQCLFDANRAELFTQSCSALGSWLNNIESQLHSDDYG----KDLTSVNILLKKQQMLEHQMEVREKEVQSLQAQALALSQED----AGLTEIDGQQRQVTDNFS-NLQQPLRLRKQKLLASKEAHQFNRDLEDEILWVTERMPLATSTEHGKDLSTVQLLIK------KNQTLQKEIQGHQPRIDDILKRGETQSQVDGERQALLEERLAELRDLWDQLISETDNRNTRLLEARRAQQFYADAAEAEAWMGEQELHMMS-EEKAKDEQSALVMVKKHQILEQTLEDYAQTIHQLANSSRLMVTNEHPESERITLRQAQVDKLYAGLKDLAEERRGRLQERLRLTQLKREVDDLEQWIAEREMVAGSHELGQDYEHVSMLRDKFREFARDTSTIGQERVDGVNALADDLIESGHPENASVAEWKDGLNEAWADLLELIDTRTQMLGASYELHRFHQDAMEVLGRVKEKREALPA--DLGRDLNTVKHLHRQHQTLENDIQALSWQVNQVQDDAARLQKAYAGEKADDIHRSEHAVSSAWEALQEACQSRRLLLQDTVEKFRFLNAVRDLMLWMDGVNLQIDAHDSPRDVSSAELVIGNHQDIKSEIDTRADSFTASIDMGNALINKSHYAADEIQEKLAQLQERRDEINKKWQDKMNYLQIVLEVLQFGRDASVAESWLAGQEPLVRAAELGTNVDEVESLLKRHEAFEKLATAWEERFVQLERLTTLEEQELQRRREEEERARRPPTPPQ-----VEEVTQSKAET--------------QAHDSEAR--TSLDQTTLNQDVSVNGVHSDNDTSQSLSLSLSVGKKSEPKRVFKPKQPERGSESESVNGPGRDSGLASSRLEASATLPGRGGADSDAECVEGMLCRKQEMESHNKKAATRSWHNVYCTLKKGGLHFFKDNKSVSSGIT--YHGEMPFSLEEAVCEVALDYKKRKHVFKLRNENGKEYLFQAKDEV 2309
BLAST of Spectrin beta chain vs. Ensembl Medaka
Match: sptbn2 (spectrin beta chain, non-erythrocytic 1 [Source:NCBI gene;Acc:101155789]) HSP 1 Score: 1273.07 bits (3293), Expect = 0.000e+0 Identity = 798/2375 (33.60%), Postives = 1321/2375 (55.62%), Query Frame = 1
Query: 166 DEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKII----AEQFLQDCDDEIDWMNEKIDLIRN--RSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-----PDEYKGIVK--DVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSID-SSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPS-NMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNP-STTQSHPNLSSS 7242
++VQY+N+ R K L DERE VQKKTFTKW+NS L VT +I DLY DLRDG+ L+ LLE+LS E +PKPT+GRMRIHCLENVDK L FL QKVHLEN+G+HDIVDGN RLTLGLIWTIILRFQ+QDI + + + KSAKDALLLWCQMKTAGYP+VNI NFT SWR GL F A++HKHRPD+I+F + R++ NL AF++AE LG+ LLDPEDVNV PDE+S+ITYVA+YYHYF+ +KA +V KR+ K+L+ +E +Q+I Y++L S+LL+WI TI LN RQ +NS+ +Q Q+ FN YRT EKP KF EK +LEVLLFTI+S + KVY P E +S IN AW+ L AE+ RE ALR EL+RQEKL LA +F++KAA+RE+W+++N L+ + + G +L V AA +KHEAIETDI AY E ++ + ++ LE E Y+D+ I+ ++ VL LW+ L + L RRE L + + L E + + + + + GKHL +V +LL+ H L+E+DI + +R++ + + A + + +Q ++ ++ EK + + EL R+E L+ S +WQF+ D E WI+E I+ + D G DL+S LL KH+ F E++++ + L N + G+ L++ G + + DI+ W L ++T+ R+ L E + +Q+ +D +D E WI E R + LG T+ L RK ++ E ++++R I + QAQ+ L + V H V +L IE+ Y++L ++ ++ L AL++Y++ +++D+ W+ EK+++L +E+LEV++ RFE E E+ +V HVN+++E L+ + N I +D LNN W + + K+ L S + N+ ++C + W++EK K+IES LG DL VM QR++ M+RD+ AI+ K+D L ++ ++ + A++I+ +L + + WE L ++ R+ +L + + F++ L+DF +WL + QT +AS++IP S EAE L+ ++ S ++E+ ++ E+ +G++ + + D Q + L R+++++ W L + E + L + F DA+Q E LN+QE L + +NL + E + ++E F+ + E+ + V+ G+ LI ++N D++Q K ++ ER KN A+ KLK+ L LQD +L + EK+ ++S ++ S + +A E+ + + +++++K G+ A+ P K + L++L W E+ K Q L NR +LF +S ++ WL NIE Q+ +DD +TS+ LKK ++E ++K +++L+ + L Q++ + +++ Q + D S L+ L + QK++ A QF +D +DEI W+ E++ L + K + T+ L++ ++++++ EI+ ++D +++ + + ++AL+ + + +L+ + L E + L Q+F D +E +W+ E+EL +M +KD+Q +++K Q LE +++Y I + S + P+ + ++ V+ + LK + E++ + + ++E WI ER +A S + G+D + ++LRD+F F+ +T+ IG +V+ N D+LI+ HP S++ WKD +NE WADLLELIDTR Q+L ++++LHR++ D+ +L ++EK+ ++ DLG+D +V L R+ + E D+ L +N + L Y +K + + + A+ +L++ + R+L + + FL+ VR+L+ W++ V +Q++ PRDVS EL++ NH+ +K E+D++ ++F+ +++G L+ H + EI+ K ++ ++RD + +KW + +++L +++EV Q+ RDA+ AE+W+ QE + LG +DE +LLK+ F+K EE+F QL+RLTT+E + + + + Q V E+ Q E + H R S+D ++L+QD + + S+ + S V + KQ +R S +++ P + +++ L AS + ++G L RK + E+ N+KA+ R+WH++Y L + + FFKD + Y EMP L E V A DY KR VF++R NG EYLFQ +M W+ +I Q +P S + P +S S
Sbjct: 17 NQVQYSNILE-----GRFKQLQDEREAVQKKTFTKWVNSHLSRVTCRIGDLYTDLRDGRMLIRLLEVLSGEQLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGLAFNAIVHKHRPDVIEFDNLKRSNAHYNLQNAFNVAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDYAIEADQLIDKYETLASELLQWIEQTIGTLNDRQLANSLNAVQNQLQAFNSYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYVPKEGKLISDINKAWERLEKAEHERELALRNELIRQEKLEMLAARFDRKAAMRETWLSENQRLVSQDNFGTDLGAVEAATRKHEAIETDINAYLERVVAVEDVAKELEAEGYHDVRRILARRDNVLRLWEYLKELLAARRERLTAHRDLQRLFQEMRYITDWMKDEQGRLQSQDTGKHLHDVLDLLQKHNLVEADISAQAERIKGVQAAAKPFSSY-EQAYK----PCEPGLVGEKVERLGQAYEELGQLASARRERLEDSRRLWQFLWDLGEEAAWIREQEQILASGDCGRDLTSALHLLSKHEAFRDEMAARFMPLNNSIAAGEALINEGHFGASEVTERIQDIRAQWAHLEETTKLREQSLKEAVALHQFQTDANDMEAWIMETLRQLSSQELGHDEFSTQTLARKQREIDEEIQSHRPLINTLHEQAQA-LPQAYVSHPQVDGRLPAIEQSYKELESLSATRRQALDGALSLYQMFSEADACLLWVEEKEQWLDGMEIPTKLEDLEVVQQRFESLEPEMNNLGARVTHVNDVAEFLLDSDNCRKDQIHQTRDQLNNRWAEFEQLAGQKKQALESALNIQNYHLECNEIKSWMKEKTKVIESTQSLGNDLAGVMALQRKLTGMERDLEAIQGKLDDLKSEAGKLASEHPDQAEEIQGRLAEIQEVWEELNATMKRREESLGEASKLQGFLRDLNDFQSWLSRTQTAVASEDIPTSLPEAENLLTQHESIKNELDNYKEDYEKMRAVGEEVTQGQTDA-QHMFLAQRLQALDTGWHELRRMWENRHSLLAQGFDFQGFMRDAKQAEAFLNSQEYVL---------HHTEMPTNLQAAEEAIRKHEDFLTTTEASEEKINSVVDSGRRLINDSNANSDKIQEKVDSIQERHNKNKEMAKELLTKLKDNRELQHFLQDGQELTLWINEKMLTAQDMSYDEARNLHSKWQKHQAFMAELASNKDWLDKIDKEGQALVAEKPELKPVVQQILEDLQHQWEEVEGTTRTKAQCLFDANRAELFTQSCSALGSWLNNIESQLHSDDYG----KDLTSVNILLKKQQMLEHQMEVREKEVQSLQAQALALSQED----AGLTEIDGQQRQVTDNFS-NLQQPLRLRKQKLLASKEAHQFNRDLEDEILWVTERMPLATSTEHGKDLSTVQLLIK------KNQTLQKEIQGHQPRIDDILKRGETQSQVDGERQALLEERLAELRDLWDQLISETDNRNTRLLEARRAQQFYADAAEAEAWMGEQELHMMS-EEKAKDEQSALVMVKKHQILEQTLEDYAQTIHQLANSSRLMVTNEHPESERITLRQAQVDKLYAGLKDLAEERRGRLQERLRLTQLKREVDDLEQWIAEREMVAGSHELGQDYEHVSMLRDKFREFARDTSTIGQERVDGVNALADDLIESGHPENASVAEWKDGLNEAWADLLELIDTRTQMLGASYELHRFHQDAMEVLGRVKEKREALPA--DLGRDLNTVKHLHRQHQTLENDIQALSWQVNQVQDDAARLQKAYAGEKADDIHRSEHAVSSAWEALQEACQSRRLLLQDTVEKFRFLNAVRDLMLWMDGVNLQIDAHDSPRDVSSAELVIGNHQDIKSEIDTRADSFTASIDMGNALINKSHYAADEIQEKLAQLQERRDEINKKWQDKMNYLQIVLEVLQFGRDASVAESWLAGQEPLVRAAELGTNVDEVESLLKRHEAFEKLATAWEERFVQLERLTTLEEQELQRRREEEERARRPPTPPQ-----VEEVTQSKAET--------------QAHDSEAR--TSLDQTTLNQDVSVNGVHSDNDTSQSLSLSLSVGKKSEPKRVFKPKQPERGSESESVNGPGRDSGLASSRLEASATLPGRGGADSDAECVEGMLCRKQEMESHNKKAATRSWHNVYCTLKKGGLHFFKDNKSVSSGIT--YHGEMPFSLEEAVCEVALDYKKRKHVFKLRNENGKEYLFQAKDEAEMNSWIQSIRRFITTRSQDSPGAPRALSRAMTMPPISPS 2329
BLAST of Spectrin beta chain vs. Planmine SMEST
Match: SMESG000039799.1 (SMESG000039799.1) HSP 1 Score: 4797.26 bits (12442), Expect = 0.000e+0 Identity = 2401/2408 (99.71%), Postives = 2404/2408 (99.83%), Query Frame = 1
Query: 85 MEICVPYLNGNYCDSLSSDYQNALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPDEYKGIVKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFSSIRLKK 7308
MEICVPYLNGNYCDSLSSDYQNALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFLL LLELLSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFN YRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDLSEEKEKRLEKYLKSLMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVLLHELLQDIDDLDDSLLEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMELENKKKLLENLKDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDT+NQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGL+INSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLP+EYKGIVKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRF IFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSV LLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFSSIRLKK
Sbjct: 1 MEICVPYLNGNYCDSLSSDYQNALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFLLALLELLSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNLYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDLSEEKEKRLEKYLKSLMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVLLHELLQDIDDLDDSLLEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMELENKKKLLENLKDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTINQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLIINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSLPEEYKGIVKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFAIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVCLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFSSIRLKK 2408
BLAST of Spectrin beta chain vs. Planmine SMEST
Match: SMESG000035098.1 (SMESG000035098.1) HSP 1 Score: 1631.69 bits (4224), Expect = 0.000e+0 Identity = 949/2395 (39.62%), Postives = 1457/2395 (60.84%), Query Frame = 1
Query: 154 LSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNST--IKD-FHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEM-EKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKI-------EEFKKSCVSLPDEYKGIVKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFSSIRLK 7305
SDEDE + + SK++ERSRIKALA+ERE VQKKTFTKW+NS L V ++DLY+DLRDGK L+ LLE+L+ E +PKPTRG+MRIHCL NVDK + FL +Q VHLENVGAHDIVDG+PRLTLGL+WTIILRFQ+QDI DE + A+SAKDALLLWCQMKTAGY +VNIRNFT SWR GL F A+IHKH P+LI++ + + NL AF+IAE+ L IP LLD ED+NV PDE+S++TYV + YHYFN +K +V KR+ K+LNQ +E E I Y +L S LLEWI +TI+LL+ R F+NS+ G+QQQ+ FN YR EKP KF +K +LE+LLFTI S + K Y P E +S IN AW++L AE+ RE LR+EL+RQEKL L +F++K +RE+W+++N L+ + + GN+L V AA KKHEAIETDI+AYEE + + +++ L EE Y+DI I K+ V+ +W+ LL+ L RR L+ Q+ + E + I I + + ++ GKHL+ V++LL+ H L+E+DIR + R +++ +A ++ D DF N+ A E N +KD + LL+ R L+ S +WQF + +++WIKE +M++PDLG+DLSSV+RLLRKHK E E+ ++ +LE L +G+ L++ G++ I K ++ +W LVD T R+ +L E L++YQ ++DCDDA+ W+ + R+ + +G K++ TE LI+ NQ M+ + +R +++Q+R Q ++ Y D + +LD ++ +Y L++++ Q+KLLDA+++Y+L + +DSV++WI EK+K L +PSD++EELEV++HRF+ FESE+ AEKV VN LS++LV + +PN + I+ QD+LN +WN +AD+V+ K+ ++ + Y Y+ F ++ Q+T WI EK KLI+S DELG DLE +MQ QRR+ +QRD+ AIEAK+DHL + D+I +E + +++ W L+ ++++RD L + +++ RF+Q LD F WL + QT +AS++IP + EAEKL++++N + E+A + E + G+ + QD Q++ L R+ I + W+ L + +++E L + L++ FF+DA+QI+ +L+ E ++K ++ TS + ++ E + +++ + +++E + +L+ G+ L+++NN D++Q KC + ER + R L Q+ L E Q+IDD+++ + EK+ + ++ S + ++ + + KA E+EI A + IE++ K G++ P F + +D L W EL+ ++K + +A NRE +F E+ +SM +W+ +I QI+ +E + G+ I Q+K + + ELENK+K+L +++ H+ LK+Q PD+ + EQ++ +V+V + + PL + ++ QFL+D +DE W+ EKI+L++N K ++ LL QQ R K++ NE+ N ++ ++ ++ + MI E H + + +L + + L ++ E+F +L + L Q++L D SE +W+ E+EL LM +KD+Q +++K Q++E I+NY +I +E SC D V+ + L+ +C+E++ + V + ++E WI ER +A S + G D + C LLRDRF F+ ETN IG ++ AN+ D LI H + I+ WKDRINE WADLLELI+TRIQLLK+AWDLH++ D Q LL+ I EKK + + +++G+D KSV+ QRK + FE+++ +L I +A+ +N LLPLY KE + +R EL+ A+R L+ E RK++ L+ AD H FLSMVREL++W+ E+ QM+ + KP+DV+G++LL+ NHRSLK E+D++EENFSICL+LGRTLL +H R +I+ KC E+ R L +W D+L L++EVYQ+ARDAA AE+W+++Q +YL+ ++LG LDETLALLKK I F++A M QEE+FE LK+LTT+E+R+K + P Q Q++I R I + + FQ P P+ P+ + + S LS D SA P T++ P +G L RKH+WE+ +KAS R+WH LYV+L+ ++ +KD++H KEKP + Y HE PL L PA DY KR VFR++ NG EYLFQ S +M W+ +N+++ + ++ Q H S + H G K+FF+ R K
Sbjct: 23 FSDEDEFEGGDSVSKLYERSRIKALAEEREIVQKKTFTKWMNSHLAKVGEFVDDLYLDLRDGKKLIKLLEILACEKLPKPTRGKMRIHCLVNVDKAINFLLDQHVHLENVGAHDIVDGSPRLTLGLVWTIILRFQMQDIVLDEYDATDARSAKDALLLWCQMKTAGYNNVNIRNFTTSWRDGLAFNAIIHKHCPELIEYMKLAKAAPLQNLRNAFNIAEDELMIPKLLDAEDINVEQPDEKSIMTYVVTLYHYFNRMKTENVQCKRIGKVLNQAIESEDRITEYDNLASDLLEWINHTIQLLDERLFANSLSGVQQQLAAFNTYRISEKPPKFNDKGNLEMLLFTIHSEMRANNQKPYIPEEGKMISDINRAWEKLEKAEHERELCLREELIRQEKLDQLGSRFDRKTTMREAWLSENQRLVTQDNFGNDLAAVEAATKKHEAIETDIFAYEERVNAVMTVAEELAEENYHDIERINLRKDNVIKMWQDLLELLKMRRNRLELSKQMQNVFQEIIYLLDWIDEIGNRLKSEDCGKHLLGVDDLLQKHGLLEADIRVLEIRKNQVLEQAEVFI---DCDFDENLQGYRPAEPSEVENRCQQLKDSYQALLELASYRHNALQESKKMWQFFWEMEDDKEWIKEKSQLMSSPDLGHDLSSVERLLRKHKALEEEVRIRQQALETGLQKGEELIENDNWGKDRIKDKIQKMKTIWAQLVDLTAERRQRLEESLEFYQLLTDCDDADAWMIDQLRIVKNEDVGTKLALTEALIKNNQDLMDELATFRQSLDQLRTQGTTISEYPETDASKIFNRLDTLDNRYDQLIELSKLRQQKLLDAMSMYKLFDVADSVKTWIIEKEKLLITLVPSDELEELEVIRHRFDCFESEMRANAEKVSKVNELSKDLVSDEHPNTENIIQKQDDLNINWNDLADMVEKKKQDIETSYKYNQFLIEAQETANWIIEKEKLIQSTDELGNDLEGIMQLQRRLGGLQRDLKAIEAKVDHLDKEADDIEEKKPEVGNIVEPERAKINELWTELKSMLKERDDKLNDSSELQRFLQDLDHFQMWLRRSQTAVASEDIPNNLQEAEKLLDQHNQLKQEIAVYHPEFERLIHFGRKVTEG-QDDAQYMFLNQRLSGIEESWEGLEKMCDDREAVLNQSLQAQTFFKDAQQIDIVLSKLENAVLK------SDLPTS---VEAVEEAIKQHDNINNNAIANEVKIDSLLESGRNLVVDNNFNADKIQRKCDEIAERRSAIRRKSSERSELLAAQLELQEFYQEIDDVEEWIGEKMIIASDDSYRDLQNVSARYGRFKAFEEEIGANKDKIEKVIKAGQELMQQRPQFAEITQIKIDELAQQWNELNNTAQDKSKKIADANRETIFNETAKSMNEWITDISSQIITTEEDSETEIGLVEINEQMKDQEKKDKELENKRKMLADMETHAVKLKEQYPDREEEIEQMQQEVRVKLTQVEAPLAGRRENLLKRKRVRQFLRDIEDEKQWIEEKINLVQNNGKIGDS---LLAVQQFIRRLKTLNNEVDNHHPRIQAVCEDGEIMISEGHPQSEKFKIAMKELWELWDQLQMKLLERFA-VLEDNLVAQQYLFDASEAEAWMGEQELYLMSPE-KAKDEQGANNLMKKHQHIEKMIENYADEIRNLGERSQEMMHSCHPQSDLVAQKQSKVDKMYAGLRDLCSERQFRLEENVKLFHLLKEIVDLETWIAERIVLASSHEMGSDYEHCCLLRDRFAEFAKETNAIGGGRICAANELCDSLINQGHAESAEIAQWKDRINESWADLLELIETRIQLLKAAWDLHKFLSDCQDLLDRITEKK--LVIPDEVGRDAKSVATYQRKHQAFEQEVHRLGQQIESAVETANHLLPLYAGQKERMICDRRDELLHAWRELQMASEFRKVHLLDAADLHRFLSMVRELINWMFEIRQQMDSKDKPKDVAGVDLLVNNHRSLKAEIDAREENFSICLSLGRTLLNRRHPRENDIREKCIEVVTLRVNLIDQWAERYDYLHLILEVYQFARDAAVAESWLMAQCTYLSCQDLGENLDETLALLKKHIAFERAVMTQEERFEALKKLTTLELRAKDSS-------------------------------------------PESQRQKDIERQKKIAEMIKE---------FQPP--------PTPKLQKSEPILDSETAIESVSSQQVASSRKLSTEHDRDSAD-HPTTSKH--PGSESHEGTLSRKHEWESTGKKASGRSWHELYVVLNDGVLSAYKDQKHGKEKPSELYHHESPLQLSGARIGPATDYTKRVNVFRLKLVNGGEYLFQAKSESEMNEWITKLNNSASGADSDTATRSSTLPLQQHGTSES-----GEGHHGKKKFFTLGRKK 2329
BLAST of Spectrin beta chain vs. Planmine SMEST
Match: SMESG000066485.1 (SMESG000066485.1) HSP 1 Score: 1346.64 bits (3484), Expect = 0.000e+0 Identity = 820/2129 (38.52%), Postives = 1279/2129 (60.08%), Query Frame = 1
Query: 94 CVPYLNGNYCDSLSSDYQNALSDEDEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHVTMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSG-------NKAMIKEKRNSTIK-DFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKLMEGKTLV-DISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTE----ILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQTVAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMK-DIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDE-NHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVSL-------PDEYKGIVKDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLN 6414
+P+ NG + D ++ +DE + TSK++ER RIKALA ERENVQKKTFTKWINS L + I+DLY DL+DGK LL+LLE+LS E +P PT+G+MRIHCLENVDK L FL Q+VHLEN+GAHDIVDGN RLTLGLIWTIILRFQ+QDI +ED + + AKDALLLWCQMKTAGYP+ N+RNF+ WR GL F A+IH+HRPDL+++S+ +R++ NL A IAE LGIP LLDPEDV+V PDE+S++TYV ++YH+F+ +KA SV +KR+ K+L+Q +E E+M+ Y L S LLEWI TI LLN R F+NS+ G+QQQ+ FN YR EKP KF EK +LE+LLF+I+S + Y P E +S IN+AW++L+ AE+ RE ALR EL+RQEKL LA +F++KA +RE+W+T+N L+ + + G +L V AA KKHEAI+TDI AYEE + +T ++ LE E Y+D+ ++ ++ V+ LW+KLL L R+ LD +V L + + II + A+ + ++ G+HLM VE+L+ H L+E DIR + ++E ++S+A F + +F ++SG N+ ++ R +K ++ LL+ RK+ L S ++W+F+ + EEQW+KE + +M NPDLG+DLSSV RL+ KHKV E ++ + L+N + G+ L+ D +P G E +A +++ LW L++ TE+R+ KL + L Y+ ++DC + E WI E +L + D+ S E I K++Q + +E+Y NI + Q + L ++ T+ +K+ I+ +Y L ++ ++ Q KL D L+++R+L +D+V++WI EK+K L + IP+D++EELEV +HRF+ FE E+ +A++V VN L+E L +P +VN + LN WN +AD+V+++R++L + Y ++ + ++C+QT EWIREK +L+ES DELG+DL +MQ QRR+ MQRD+ AI AK++HL + D ++ + I + ++ W L ++ DRD L+ +++ RF+Q LD H WL +MQT +AS+++P+ ++AEK + ++ ++E+ + + + + G+ + + D Q++ L R+ ++ + W+ L + E ++ L + L +F DA Q E +L +E +L K DI I N NLL ++E F+ + ++ V++ G+ L+ + D++ + +++ ER + N + KLK+QVL EL QDIDDL + EK+ + + S K+ + +A ++EI A + + + Q + P I +D+LN W EL + K + + NRE +FEE T +M WL+ I I+ +E +T + +LKK++ + E+E K+K +++LK H+ LK++ P+KA EQ ++ L +P+++K Q+ +QFL++ DD+ W+++K+ L ++ LL QQL RH+ + E+ N +++ L +E +I+E + ++R V + +L+ L ++ Q L A Q FL D E SW+ E+EL L+ +D + VI+K + I++Y +I + L D V+ + L+ +C EKK +S Y ++E WI ERT +A S D G D + C LLR+RF F ET+ +G +V AN LI H + I+ W DRIN+ WA+L EL+ TRIQLL++AW+ +++ Q +L+ I EK +S + D+ KD +SV++ QRK F D L+ + + +N LLP Y KE + ++R +++ + L E R+ + AD F SMVRELL W++ V +Q+ + +P+DVSG+ELL+ +HRS+K E+ ++EE+ SIC+NLGRTLL + E+++ + ++ L W D+L L++EVYQ+ARDA+ AEAW+++QE YL N+ LG TLDETL+LLKK I F+K M+QEE+F+ L++LTTMEIR+K++
Sbjct: 7 TLPWSNG------TGDTNGNITTDDEWDTEDSTSKLYERFRIKALAGERENVQKKTFTKWINSHLNKLKQSIDDLYNDLKDGKMLLLLLEILSGEQLPYPTKGKMRIHCLENVDKSLNFLIEQRVHLENMGAHDIVDGNARLTLGLIWTIILRFQIQDIVVEEDDTSEKRQAKDALLLWCQMKTAGYPNTNVRNFSTCWRDGLAFNAIIHRHRPDLLEYSALSRSNPNENLEQAIRIAEEKLGIPRLLDPEDVSVENPDEKSIMTYVVTFYHFFSKMKADSVHSKRVGKILSQSMETEEMMVHYDKLTSNLLEWINQTIELLNDRTFANSLSGVQQQLAAFNTYRVTEKPPKFQEKGNLEMLLFSIQSQMRANNQVPYLPIEGKLISDINNAWNKLDKAEHARELALRDELIRQEKLEQLALRFDRKAGMREAWLTENQRLITQDNFGQDLSAVEAAGKKHEAIKTDILAYEERVNSVTLVTSELENECYHDVERVLCRRDNVIRLWEKLLDMLAVRKLRLDACYKVQKLFQDIKHLLDIINDLKARLKTEDIGRHLMGVEDLIHKHSLLEIDIRMVGTKIEGIMSDAQ---PFINSEF--GLDSGDFQPADPNEVIL---RTVNLKEEYDNLLELSRNRKDNLSASKVMWEFLWGVADEEQWMKEKIQLMLNPDLGHDLSSVHRLISKHKVIEEDVRNHSNYLQNVIQAGQQLILDKNP-GAEKVADNLKELELLWNELIELTENRRSKLEQSLAYFHCLADCGEVEIWIIEQVKLVKI----DETSINEESIITDIHKHEQLSKSIEDYESNINSLDEQVKK-LSEGDLELVTIEEKVSNIKSQYAILFELTNQKQNKLTDTLSLFRVLRKADTVKTWIDEKEKLLMSLIPTDELEELEVFRHRFDGFEKEMNIQADQVEFVNTLAEKLSDMDHPQIADVVNKRFELNKLWNSLADLVEARREQLQTSYEFNQYLLECKQTGEWIREKSRLVESTDELGDDLAGIMQLQRRMGGMQRDMDAIRAKLEHLDEEMDTLIAKRPNDEELIREERMILEDFWAELGDMLADRDDRLSESSELQRFLQDLDHIHIWLSKMQTTVASEDLPKDLADAEKSLVQHEQLKEEIDSYQDEFIRLLDYGRRITEDKTDA-QYMFLSQRLNALEEGWQELCQMWENRQGLLSQSLSLQVFLRDAIQSEVLLAQEENFLSKEDIPISIEN----SQNLL------RKHEGFLTTLQANHDHTIAVIEFGRNLVERGHFCSDKINLRVKSILERRESNKRRSNEAYEKLKDQVLYQELSQDIDDLSKWIQEKMIIATDESFREEKNIARRYNRHRAFDEEIQANKDRLCQAIDYAMQIVEERPQLADMIYPQIDSLNQQWEELEQTTFLKGEKMIEANREAIFEEGTMDVMTWLETIGESIIVTEE---EVETLTDVNVKLKKVEEADNEMEIKRKQIQDLKMHAAKLKEEQPEKAFGIEQKHLILEHRFTQLQMPIKNKKIQLIQRKRIQQFLRNLDDQKAWVDDKLLL----AESTNFGNNLLTVQQLLRRHRYLATEVNNHKPQLEYLKEEGAVLIEEVSPMQREKFVAGLQELESLWNRLEHSIDLRQQRLKESEATQTFLFDAEEAESWLWEQELFLLSEERGIRDQEAAINVIKKHDARQKTIEDYGEEITKLGTRSRLLIEKDHPQADRIALAQSHVDKVYAGLRDLCLEKKQRLSEIQKLNHLYREIVDLENWIYERTLVASSHDLGVDFEHCCLLRERFDEFFHETHLLGKDRVKAANDLCASLISQCHADSAEIAQWHDRINDSWAELQELMQTRIQLLRTAWEFYKYLSSCQDVLDRICEKIAS--IPTDVSKDSQSVAIQQRKHATFLSDAQALEGQVQWVVDEANHLLPSYAGQKEWHICERRDDVLATWNQLNMQAERRRHQLEDAADLQRFFSMVRELLQWMDLVALQINEKTRPKDVSGVELLINDHRSIKAEIAAREESMSICVNLGRTLLHRGRVGVDEVRAALINLITRKYSLEDMWEERWDYLQLILEVYQFARDASVAEAWILAQEPYLANKTLGETLDETLSLLKKHINFEKTVMSQEERFQALEKLTTMEIRAKEIT 2095 HSP 2 Score: 134.42 bits (337), Expect = 7.866e-31 Identity = 76/234 (32.48%), Postives = 128/234 (54.70%), Query Frame = 1
Query: 6616 IKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTRTIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLS--QSRMTFFKDERHFKEKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRN-GAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFSSIRLKK 7308
+KD +++ + + +P P + P++ S+ + + H +SV + + + + T+T ++G L RKH+WE +N+KA NR+WH V+LS ++++ +KDE+H+ EKP+ Y + L L ++VAAPA DYLKRP VFR++ + GAEYLFQ DM RWV++IN S+ + + T P + + P +S + G K+ F ++ KK
Sbjct: 2101 LKDKHKQERIENAIKIFQPPPSPELVHESPKVSISEEDEEGKSHQ--HKISVISKEAAEMCQSSETKTD------IRGILIRKHEWEYKNRKALNRSWHEFLVVLSIEKNKLLVYKDEKHYNEKPQDTYHKDSGLDLNDLVAAPASDYLKRPFVFRIKITSTGAEYLFQAKDEEDMLRWVNSINENSQ--KDLKSETTAPGKSSTLPACTSDPHVPSTQATGFKKKFFTLTRKK 2324
BLAST of Spectrin beta chain vs. Planmine SMEST
Match: SMESG000081696.1 (SMESG000081696.1) HSP 1 Score: 1299.26 bits (3361), Expect = 0.000e+0 Identity = 829/2405 (34.47%), Postives = 1386/2405 (57.63%), Query Frame = 1
Query: 166 DEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHV--TMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKL--MEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQT---VAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVS-LPDEYKGIV--------------KDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTR-TIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFK-EKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFSSIRLKK 7308
D ++ N ++ ++ERSRIKAL+++RE VQKKTFTKW+NS L+ ++DL+VDL+DGK LL LLE+LS E +P T+G++RIHC+ENV K + FL +Q V EN+GAHDIVDGNP L LGLIWTIILRFQ+QD DE +++K++LLLWCQMKTAGY +VNIRNFT+SW+ GL F AL+HKHRP+++D+ + + + + NL+ AF+ AE G+P LLD D+ V P+E+S++TYV S N +K + KRL ++N+ + E++I Y+ L +LLEWI+ I + + + S+PG+++Q+ F+ YR EKP KF ++ LE+ F I+S K+Y PPE +S IN AWD L +E+ E L +EL+RQ+KL L FN+KA +R+ W+ +N L+ ++ G++L T++AA+KKHEA+E DI+A+EE + L I+D+L+ E Y I + + ++++WKKLL L RR+ LD + ++ E + + IT + + ++GKHL+ VE LL H+++ SDIR++ R I + +R +Q D D R+ I+ M K + ++ EL+ ++R++ L ++W++I D + +++WIKE++ + +PD G+DL SV+RL+RK + +++ ++ + +KL + KT D SP QE I + ++I L + L + +R+ +L + D++Q ++D +DA+ I E +RLF+ +GDK+S TE ++++++ M VE I ++ + L +D Q + +R++ ++DL+D+A+ + LL+ + L ++ +++ +WI K+K L +PS++++EL V+KHRF+ FE ++ + KV N +S +L+ +P +II Q+ LN WN++AD+ + K+ EL Y+ F ++ Q+T WI++K+KL+E D+L +DLE +MQ QRR+ +QRD+ AIEAK+ +L + D++ I+ ++ V++ WE L+ +++DRD+ L + N++ +F + LD F WL ++Q ++A+Q+IP+ EAE+ + ++E+ E + ++ G+ S+ D Q++ R+ + +W L + ++K+ L + + F D+ QI+ IL QE +L K L NN+ +K+ E E F + + S++ + V+ G++L+ N L D+++NKC+ + R R + L++ +LL E D+ L++ + EK+ + ++ S + K + + K E E+ A R ++E+ ++G + + PHF+ EI + L + W+EL EK + L NRE +F+E+T+SMM W+ I QI+ E G+ + ++K + + +L+ K+K+L +++ H+E LK+Q P++ ++E ++ +VKV + + PL + +I QK +QFL+D +DE +W+ EK++ I ET+ LQ + R K+ EI N + ++ L E + MI + +++L K ++L E Q VQE+L + E W+SE+E DLM +KD+ +RK + L I NY S VS L D+Y I+ + V+ + L +C EKK +I + + Y Q +E WI ER+++A S++ G +L+ C LLR+RF F+ +TN++GSS+V +A++ D+LI H + I+ WKDRINE WADLLELI+TRIQLLK+A+D ++ DS LL+ I EK + V +GKD KSV+ QRK F ++ +L+ I+NA+ +++ LLP+Y +KE + ++ EL + SL+K E+R + ++ +D + F +MVREL++W+ E+ IQ+ K RDV G+EL+++NHRSLK E+DS++EN SIC+ LGRTL+ KH ++ +++ K KE+ K + + W + L +++EVYQ+AR+AA AEAW+I+QE LN ++ G TL+ETL LL+K + ++ Q ++FE LK+LT+ E K L +++ E L + E+ E + E P P P +R+ +I L +D ++ P S S V ++ P + + +PK T+ T P+ G L RKH+WEN +KA NR W+ LYV++ S+M+ +K+ ++++ +K +Q YKHE P+ L +++PA +Y KRP VFR+R +NGAEYLF+ +M +WV+ IN ++ +T+ + + PN+ S K+ F ++ K+
Sbjct: 13 DVLENDNNSALLYERSRIKALSEQREAVQKKTFTKWVNSHLMKSKEPYHVDDLFVDLQDGKALLKLLEILSGEKMPPITKGKLRIHCIENVTKSINFLNDQHVCFENLGAHDIVDGNPTLILGLIWTIILRFQIQDAAIDE--KDGKRTSKESLLLWCQMKTAGYNNVNIRNFTSSWKDGLAFNALLHKHRPEVVDYVTLTKANPVENLNFAFETAEREFGVPQLLDARDIIVDQPEEKSIMTYVGSLCLALNKVKRNEKQCKRLGNVINEAISAEKLINNYEELSEELLEWIKLKIDWMENEKLNESLPGVREQLGDFSNYRLTEKPPKFQDRGLLEMNFFEIQSKLRADNRKLYVPPEGKLISAINRAWDNLEKSEHRMELRLYEELIRQQKLEQLGNHFNRKAQMRKDWLIENDILVHQKIFGDDLVTIVAAIKKHEALEGDIFAHEERINALGYIADDLKSENYYKITEVEDCYFMIVEMWKKLLDDLQTRRDKLDRCRDIQMILQETDYLMDWMREITIRLQSRDFGKHLLGVENLLEKHKILLSDIRNLEGR----IDDTSRKLQTADFD-RAAIDQDYVDM---KEKQLVNNYQELILLSEQREDELNCYKVMWEYIEDINNDKEWIKEIIQLFQSPDSGHDLRSVERLIRKFEQILSDVTVRKDLIVDKLDSIVHKTSNDPSPQRQEIIHREIDEINELLDNLDQAMRNRRNQLNQSHDFHQLLADIEDADAMILEERRLFENSDVGDKLSLTEYYLKQHEEQMLQVEELEKLITELFGRKNDLE----LDSQQQNDADEACERMKNDFEDLVDLANTRKHLLLNNKDKFHLFSNFETIETWIIAKEKLLVTLVPSEELDELNVIKHRFDCFEDDMKIHSGKVSEANQISRDLINEQHPELEIISEKQNILNLDWNQLADLAEQKKKELQLAVDYNQFILESQETQSWIQDKMKLLEWTDDLKDDLEGIMQLQRRLGSLQRDVQAIEAKVKYLNKEADKLKVAKPADEATIDSEITAVNELWEELKIMLQDRDARLNSSNELQKFFKDLDSFDVWLKKVQIQVATQDIPKDLQEAERYCTNHLEVKEEILCWEPEYVRLLQFGRQVSHSKDDP-QYLLFNERLNVLENEWNALEKMWKDKDVSLHESKDAQTFIRDSLQIDGILTQQESFLSK--SELPNNYEATKAT-------EREFEAFKNSVASNKPKIDAVVNFGESLLASNAL-SDKIRNKCEQIHSRCDAIQDKIDRRNSALQDHLLLLEFSDDVLALEEWMSEKMIIASDTSYRDTKDISTRYNRFKDFERELEANRESVDEVIEKGNKLIDEKPHFESEIEPKVVELENQWSELLNTATEKSKQLEEANREIIFDETTKSMMSWVTEISSQIIT-TEEIIEEYGLVELNEKMKDQEDKDKQLDQKRKMLSDIEQHAEKLKEQYPERGDEFELIQQEVKVKLTEIEAPLTDRRNILLQKKRVQQFLRDVEDEKEWIREKLEFITKFKIAPETLQVCLQRIR---RLKTNNTEIDNHAGRITDLNNEGEEMIRNDFPSSDKFNIALDELNKLWDDLITACEDCQQFFEENREVQEYLSEAIECEYWMSEREFDLMR-EDKAKDEGGALNAMRKHEELISVINNY--------GSIVSKLADKYHHILNCDLPGSHLVAQKQERVDKMYADLLEMCLEKKLKIEDLIQFYHLYRSIQGLEEWIAERSQVACSNEIGSELEHCILLRERFSEFAIQTNEVGSSRVKDADEMCDKLIALGHQESPEIARWKDRINEAWADLLELIETRIQLLKAAYDFFKFMSDSSELLDLIHEKIRLIPEV--VGKDAKSVATAQRKHNAFATEIERLEPLISNALGIADKLLPMYGGEKEQEITDRKIELQKLWFSLQKDYENRHNSLMDASDLYKFYAMVRELVNWMGEIEIQINADDKARDVCGVELIISNHRSLKAEIDSRDENRSICITLGRTLINRKHPKANDVRKKAKEVLIKHFNILENWRERQEFLEMILEVYQFAREAAVAEAWLIAQELQLNTDDFGDTLNETLNLLQKHLDLERNLAVQADRFETLKKLTSFEETQKSLTAEKK--REKLKDREKRLELTIREFNTP-----------PPTPEP-------VRKVEAI-KQLSED-----------------IIVPLQSRSVQSAVAIDDSAEAPPKQEVKEKS----------KENPKLIETKSTTEPK----TGTLTRKHEWENSTKKAGNRKWYELYVVIENSKMSVYKERKYYEDDKKQQTYKHEKPIDLIGAISSPATNYKKRPNVFRMRIQNGAEYLFEAHDQAEMNQWVEKIN-------EIGGVDTSLAKYSTLPNIKSDFEMPVTEASSEKKKFPTLGRKQ 2318
BLAST of Spectrin beta chain vs. Planmine SMEST
Match: SMESG000081696.1 (SMESG000081696.1) HSP 1 Score: 1298.88 bits (3360), Expect = 0.000e+0 Identity = 829/2405 (34.47%), Postives = 1386/2405 (57.63%), Query Frame = 1
Query: 166 DEVQYANVTSKVFERSRIKALADERENVQKKTFTKWINSTLIHV--TMKIEDLYVDLRDGKFXXXXXXXXSNEIVPKPTRGRMRIHCLENVDKCLGFLFNQKVHLENVGAHDIVDGNPRLTLGLIWTIILRFQVQDIQFDEDYSPVAKSAKDALLLWCQMKTAGYPSVNIRNFTNSWRTGLGFVALIHKHRPDLIDFSSCNRNDNINNLHLAFDIAENALGIPSLLDPEDVNVPLPDERSVITYVASYYHYFNSLKASSVLNKRLNKLLNQVLEDEQMIQLYQSLVSKLLEWIRNTIRLLNMRQFSNSIPGIQQQMNTFNFYRTGEKPSKFVEKVDLEVLLFTIKSNQFVSRLKVYNPPEEFSLSTINSAWDELNTAEYGRETALRKELMRQEKLRNLAQKFNKKAALRESWITDNMELLQKQSLGNNLPTVLAALKKHEAIETDIYAYEENLIGLTKISDNLEEEIYNDIISIINTKNKVLDLWKKLLQTLHERREHLDNYLQVYTLINEFCEVQAIITGITAKQRIDNYGKHLMEVEELLRSHELIESDIRSINQRLEKLISEANRYVQFCDQDFRSNINSGNKAMIKEKRNSTIKDFHELLDSLDKRKEILKHSHLVWQFIVDASLEEQWIKELVDIMNNPDLGYDLSSVDRLLRKHKVFELELSSKRISLENKL--MEGKTLVDISPVGQEFIAAKNNDIQNLWEALVDSTESRKIKLLEMLDYYQYVSDCDDAECWIDEFKRLFDLKFLGDKMSFTEILIRKNQQNMEIVENYRDNIEQIRNQAQSLLGYSIVDHQT---VAKKLDRIEKKYQDLLDIAHKMQEKLLDALTVYRLLNDSDSVRSWITEKQKFLCNFIPSDDIEELEVLKHRFEVFESELTKRAEKVYHVNNLSENLVVNGNPNHQIIVNNQDNLNNSWNKMADIVDSKRDELLSKYHYSNFFMDCQQTIEWIREKIKLIESMDELGEDLESVMQRQRRINHMQRDICAIEAKIDHLVAQGDEILRHNLRSAKDIEHQLDLVHQEWEILQQLIRDRDSTLANKNDIHRFIQKLDDFHNWLGQMQTEMASQNIPESQSEAEKLINKYNSQRDEMAAMEQQLEEWMKIGKDFLKSEQDKDQFVRLQNRIESINQDWKILNDXXXXXXXXXXXXXXXXMFFEDARQIEKILNAQEKYLMKDIQSLINNFNTSKSNLLSLNEIVNENEIFIDKMLSDEKLLAIVLKQGKTLILENNLYKDRMQNKCQNLDERWKKNTLAAQNRKNKLKEQVXXXXXXXXXXXXXXXXXEKIQVLNEISMLNNKSTDSCLAQCKALEDEINAYRPIIEELNKRGKQTSADFPHFKKEIIDHLDNLNSTWAELSKALEEKLQNLAHFNREKLFEESTQSMMKWLKNIEGQIVADDEPDGSRSGITSITNQLKKLDSHNMXXXXXXXXXXXXXDHSELLKQQNPDKASKYEQLETQVKVTMDGLSVPLESKLSIANQKIIAEQFLQDCDDEIDWMNEKIDLIRNRSKQMETICTLLQFQQLQMRHKSMKNEIRNRSVKVDSLIQEAQRMIDENHLKRALVVDTVNQLKKTRENLNEEMEKFQNMLSNQLAVQEFLLDVSEVSSWISEKELDLMGLVINSKDDQLIRRVIRKEQNLEMEIKNYYPKIEEFKKSCVS-LPDEYKGIV--------------KDVEDNFNSLKIICAEKKTEISLFVIYCDTYELYQNIEAWIVERTKIARSDDSGKDLDQCTLLRDRFVIFSSETNKIGSSKVNEANKRFDELIQGKHPFAHSISVWKDRINEIWADLLELIDTRIQLLKSAWDLHRWYCDSQFLLECIQEKKSSMEVVNDLGKDPKSVSLLQRKLKNFEKDLLKLDSDINNAITVSNTLLPLYCKDKEATLIKKRQELIDAFRSLRKILEDRKLNNLELADFHNFLSMVRELLHWIEEVTIQMEMRHKPRDVSGIELLLANHRSLKIEMDSKEENFSICLNLGRTLLRTKHIRSPEIKSKCKEITDKRDILFQKWFNVLDHLSLMVEVYQWARDAASAEAWVISQESYLNNENLGMTLDETLALLKKFILFQKANMNQEEKFEQLKRLTTMEIRSKKLNTDRQFINEALINIEQTAEHEVHEIIQPITENVQTFEHKPIIHRPFEQHQQNIRRFNSIDSSLDQDSEIKDTGYFQKVNSRQSMMRPFPQSSALSPVPQMKQSKRPQPSNMSKPVHNLSVSTDMLSASPKPATTR-TIPPEEVLMKGPLYRKHQWENRNQKASNRTWHSLYVLLSQSRMTFFKDERHFK-EKPKQFYKHEMPLVLCEVVAAPAQDYLKRPCVFRVRFRNGAEYLFQGSSVVDMTRWVDAINSASRPMRQVNPSNTNPSTTQSHPNLSSSLPPQAQHHKGLKRFFSSIRLKK 7308
D ++ N ++ ++ERSRIKAL+++RE VQKKTFTKW+NS L+ ++DL+VDL+DGK LL LLE+LS E +P T+G++RIHC+ENV K + FL +Q V EN+GAHDIVDGNP L LGLIWTIILRFQ+QD DE +++K++LLLWCQMKTAGY +VNIRNFT+SW+ GL F AL+HKHRP+++D+ + + + + NL+ AF+ AE G+P LLD D+ V P+E+S++TYV S N +K + KRL ++N+ + E++I Y+ L +LLEWI+ I + + + S+PG+++Q+ F+ YR EKP KF ++ LE+ F I+S K+Y PPE +S IN AWD L +E+ E L +EL+RQ+KL L FN+KA +R+ W+ +N L+ ++ G++L T++AA+KKHEA+E DI+A+EE + L I+D+L+ E Y I + + ++++WKKLL L RR+ LD + ++ E + + IT + + ++GKHL+ VE LL H+++ SDIR++ R I + +R +Q D D R+ I+ M K + ++ EL+ ++R++ L ++W++I D + +++WIKE++ + +PD G+DL SV+RL+RK + +++ ++ + +KL + KT D SP QE I + ++I L + L + +R+ +L + D++Q ++D +DA+ I E +RLF+ +GDK+S TE ++++++ M VE I ++ + L +D Q + +R++ ++DL+D+A+ + LL+ + L ++ +++ +WI K+K L +PS++++EL V+KHRF+ FE ++ + KV N +S +L+ +P +II Q+ LN WN++AD+ + K+ EL Y+ F ++ Q+T WI++K+KL+E D+L +DLE +MQ QRR+ +QRD+ AIEAK+ +L + D++ I+ ++ V++ WE L+ +++DRD+ L + N++ +F + LD F WL ++Q ++A+Q+IP+ EAE+ + ++E+ E + ++ G+ S+ D Q++ R+ + +W L + ++K+ L + + F D+ QI+ IL QE +L K L NN+ +K+ E E F + + S++ + V+ G++L+ N L D+++NKC+ + R R + L++ +LL E D+ L++ + EK+ + ++ S + K + + K E E+ A R ++E+ ++G + + PHF+ EI + L + W+EL EK + L NRE +F+E+T+SMM W+ I QI+ E G+ + ++K + + +L+ K+K+L +++ H+E LK+Q P++ ++E ++ +VKV + + PL + +I QK +QFL+D +DE +W+ EK++ I ET+ LQ + R K+ EI N + ++ L E + MI + +++L K ++L E Q VQE+L + E W+SE+E DLM +KD+ +RK + L I NY S VS L D+Y I+ + V+ + L +C EKK +I + + Y Q +E WI ER+++A S++ G +L+ C LLR+RF F+ +TN++GSS+V +A++ D+LI H + I+ WKDRINE WADLLELI+TRIQLLK+A+D ++ DS LL+ I EK + V +GKD KSV+ QRK F ++ +L+ I+NA+ +++ LLP+Y +KE + ++ EL + SL+K E+R + ++ +D + F +MVREL++W+ E+ IQ+ K RDV G+EL+++NHRSLK E+DS++EN SIC+ LGRTL+ KH ++ +++ K KE+ K + + W + L +++EVYQ+AR+AA AEAW+I+QE LN ++ G TL+ETL LL+K + ++ Q ++FE LK+LT+ E K L +++ E L + E+ E + E P P P +R+ +I L +D ++ P S S V ++ P + + +PK T+ T P+ G L RKH+WEN +KA NR W+ LYV++ S+M+ +K+ ++++ +K +Q YKHE P+ L +++PA +Y KRP VFR+R +NGAEYLF+ +M +WV+ IN ++ +T+ + + PN+ S K+ F ++ K+
Sbjct: 5 DVLENDNNSALLYERSRIKALSEQREAVQKKTFTKWVNSHLMKSKEPYHVDDLFVDLQDGKALLKLLEILSGEKMPPITKGKLRIHCIENVTKSINFLNDQHVCFENLGAHDIVDGNPTLILGLIWTIILRFQIQDAAIDE--KDGKRTSKESLLLWCQMKTAGYNNVNIRNFTSSWKDGLAFNALLHKHRPEVVDYVTLTKANPVENLNFAFETAEREFGVPQLLDARDIIVDQPEEKSIMTYVGSLCLALNKVKRNEKQCKRLGNVINEAISAEKLINNYEELSEELLEWIKLKIDWMENEKLNESLPGVREQLGDFSNYRLTEKPPKFQDRGLLEMNFFEIQSKLRADNRKLYVPPEGKLISAINRAWDNLEKSEHRMELRLYEELIRQQKLEQLGNHFNRKAQMRKDWLIENDILVHQKIFGDDLVTIVAAIKKHEALEGDIFAHEERINALGYIADDLKSENYYKITEVEDCYFMIVEMWKKLLDDLQTRRDKLDRCRDIQMILQETDYLMDWMREITIRLQSRDFGKHLLGVENLLEKHKILLSDIRNLEGR----IDDTSRKLQTADFD-RAAIDQDYVDM---KEKQLVNNYQELILLSEQREDELNCYKVMWEYIEDINNDKEWIKEIIQLFQSPDSGHDLRSVERLIRKFEQILSDVTVRKDLIVDKLDSIVHKTSNDPSPQRQEIIHREIDEINELLDNLDQAMRNRRNQLNQSHDFHQLLADIEDADAMILEERRLFENSDVGDKLSLTEYYLKQHEEQMLQVEELEKLITELFGRKNDLE----LDSQQQNDADEACERMKNDFEDLVDLANTRKHLLLNNKDKFHLFSNFETIETWIIAKEKLLVTLVPSEELDELNVIKHRFDCFEDDMKIHSGKVSEANQISRDLINEQHPELEIISEKQNILNLDWNQLADLAEQKKKELQLAVDYNQFILESQETQSWIQDKMKLLEWTDDLKDDLEGIMQLQRRLGSLQRDVQAIEAKVKYLNKEADKLKVAKPADEATIDSEITAVNELWEELKIMLQDRDARLNSSNELQKFFKDLDSFDVWLKKVQIQVATQDIPKDLQEAERYCTNHLEVKEEILCWEPEYVRLLQFGRQVSHSKDDP-QYLLFNERLNVLENEWNALEKMWKDKDVSLHESKDAQTFIRDSLQIDGILTQQESFLSK--SELPNNYEATKAT-------EREFEAFKNSVASNKPKIDAVVNFGESLLASNAL-SDKIRNKCEQIHSRCDAIQDKIDRRNSALQDHLLLLEFSDDVLALEEWMSEKMIIASDTSYRDTKDISTRYNRFKDFERELEANRESVDEVIEKGNKLIDEKPHFESEIEPKVVELENQWSELLNTATEKSKQLEEANREIIFDETTKSMMSWVTEISSQIIT-TEEIIEEYGLVELNEKMKDQEDKDKQLDQKRKMLSDIEQHAEKLKEQYPERGDEFELIQQEVKVKLTEIEAPLTDRRNILLQKKRVQQFLRDVEDEKEWIREKLEFITKFKIAPETLQVCLQRIR---RLKTNNTEIDNHAGRITDLNNEGEEMIRNDFPSSDKFNIALDELNKLWDDLITACEDCQQFFEENREVQEYLSEAIECEYWMSEREFDLMR-EDKAKDEGGALNAMRKHEELISVINNY--------GSIVSKLADKYHHILNCDLPGSHLVAQKQERVDKMYADLLEMCLEKKLKIEDLIQFYHLYRSIQGLEEWIAERSQVACSNEIGSELEHCILLRERFSEFAIQTNEVGSSRVKDADEMCDKLIALGHQESPEIARWKDRINEAWADLLELIETRIQLLKAAYDFFKFMSDSSELLDLIHEKIRLIPEV--VGKDAKSVATAQRKHNAFATEIERLEPLISNALGIADKLLPMYGGEKEQEITDRKIELQKLWFSLQKDYENRHNSLMDASDLYKFYAMVRELVNWMGEIEIQINADDKARDVCGVELIISNHRSLKAEIDSRDENRSICITLGRTLINRKHPKANDVRKKAKEVLIKHFNILENWRERQEFLEMILEVYQFAREAAVAEAWLIAQELQLNTDDFGDTLNETLNLLQKHLDLERNLAVQADRFETLKKLTSFEETQKSLTAEKK--REKLKDREKRLELTIREFNTP-----------PPTPEP-------VRKVEAI-KQLSED-----------------IIVPLQSRSVQSAVAIDDSAEAPPKQEVKEKS----------KENPKLIETKSTTEPK----TGTLTRKHEWENSTKKAGNRKWYELYVVIENSKMSVYKERKYYEDDKKQQTYKHEKPIDLIGAISSPATNYKKRPNVFRMRIQNGAEYLFEAHDQAEMNQWVEKIN-------EIGGVDTSLAKYSTLPNIKSDFEMPVTEASSEKKKFPTLGRKQ 2310 The following BLAST results are available for this feature:
BLAST of Spectrin beta chain vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Spectrin beta chain vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Spectrin beta chain vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Spectrin beta chain vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Spectrin beta chain vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Spectrin beta chain vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Spectrin beta chain vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Spectrin beta chain vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Spectrin beta chain vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Spectrin beta chain vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Spectrin beta chain vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Spectrin beta chain vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Spectrin beta chain vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Spectrin beta chain vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30003374 ID=SMED30003374|Name=Spectrin beta chain|organism=Schmidtea mediterranea sexual|type=transcript|length=7443bpback to top protein sequence of SMED30003374-orf-1 >SMED30003374-orf-1 ID=SMED30003374-orf-1|Name=SMED30003374-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2409bp MEICVPYLNGNYCDSLSSDYQNALSDEDEVQYANVTSKVFERSRIKALADback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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