distal-less

Overview
Namedistal-less (AFC87781.1)
Smed IDSMED30003366
Length (bp)1974
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of distal-less (SMED30003366) t-SNE clustered cells

Violin plots show distribution of expression levels for distal-less (SMED30003366) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of distal-less (SMED30003366) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for distal-less (SMED30003366) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30003366

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
eyeSMED30003366SMESG000045025.1 SmedASXL_012281SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult fluorescence in situ hybridization evidence
eyeSMED30003366SMESG000045025.1 SMED30003366smed_20140614PMID:27034770
Currie et al., 2016		whole organism asexual adult fluorescence in situ hybridization evidence
eyeSMED30003366SMESG000045025.1 JN983829smed_ncbi_20200123PMID:27034770
Currie et al., 2016		whole organism asexual adult fluorescence in situ hybridization evidence
X2 cellSMED30003366SMESG000045025.1 SmedASXL_012281SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30003366SMESG000045025.1 dd_Smed_v4_19040_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30003366SMESG000045025.1 dd_Smed_v4_19040_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30003366SMESG000045025.1 dd_Smed_v6_19040_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30003366SMESG000045025.1 SMED30003366smed_20140614PMID:21852957
Lapan et al., 2011		whole organism asexual adult fluorescence in situ hybridization evidence
cephalic gangliaSMED30003366SMESG000045025.1 SMED30003366smed_20140614PMID:21852957
Lapan et al., 2011		whole organism asexual adult fluorescence in situ hybridization evidence
anterior region of the whole animalSMED30003366SMESG000045025.1 SMED30003366smed_20140614PMID:21852957
Lapan et al., 2011		whole organism asexual adult fluorescence in situ hybridization evidence
dorsal region of the whole animalSMED30003366SMESG000045025.1 SMED30003366smed_20140614PMID:21852957
Lapan et al., 2011		whole organism asexual adult fluorescence in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of distal-less vs. Ensembl Human
Match: DLX1 (distal-less homeobox 1 [Source:HGNC Symbol;Acc:HGNC:2914])

HSP 1 Score: 137.117 bits (344), Expect = 7.306e-36
Identity = 79/154 (51.30%), Postives = 99/154 (64.29%), Query Frame = 1 
Query:  814 ARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQ---DPSILMNGE 1266
            A +F+ P G     S   H    Y ++  +Y  S S+A      Q  +  P       S K  +    ++R +GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG    + S L NG 
Sbjct:   60 ASSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLA------QSRLEDPGAD----SEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGR 203
[Close]
BLAST of distal-less vs. Ensembl Human
Match: DLX6 (distal-less homeobox 6 [Source:HGNC Symbol;Acc:HGNC:2919])

HSP 1 Score: 133.65 bits (335), Expect = 9.900e-36
Identity = 63/84 (75.00%), Postives = 74/84 (88.10%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            K  +    +IR +GKGKKIRKPRTIYSSLQLQ L+ RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG +P
Sbjct:   21 KTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNP 104
[Close]
BLAST of distal-less vs. Ensembl Human
Match: DLX6 (distal-less homeobox 6 [Source:HGNC Symbol;Acc:HGNC:2919])

HSP 1 Score: 136.346 bits (342), Expect = 4.035e-35
Identity = 63/84 (75.00%), Postives = 74/84 (88.10%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            K  +    +IR +GKGKKIRKPRTIYSSLQLQ L+ RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG +P
Sbjct:  149 KTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNP 232
[Close]
BLAST of distal-less vs. Ensembl Human
Match: DLX1 (distal-less homeobox 1 [Source:HGNC Symbol;Acc:HGNC:2914])

HSP 1 Score: 129.798 bits (325), Expect = 5.244e-34
Identity = 72/138 (52.17%), Postives = 91/138 (65.94%), Query Frame = 1 
Query:  814 ARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLI 1227
            A +F+ P G     S   H    Y ++  +Y  S S+A      Q  +  P       S K  +    ++R +GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+
Sbjct:   60 ASSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLA------QSRLEDPGAD----SEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLM 187
[Close]
BLAST of distal-less vs. Ensembl Human
Match: DLX2 (distal-less homeobox 2 [Source:HGNC Symbol;Acc:HGNC:2915])

HSP 1 Score: 132.494 bits (332), Expect = 2.169e-33
Identity = 62/85 (72.94%), Postives = 74/85 (87.06%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPS 1248
            KED++ E +I V+GK KK+RKPRTIYSS QL  L +RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQNRRSK+KK+ K G+ PS
Sbjct:  135 KEDLEPEIRI-VNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPS 218
[Close]
BLAST of distal-less vs. Ensembl Celegans
Match: ceh-43 (Homeobox protein ceh-43 [Source:UniProtKB/Swiss-Prot;Acc:Q18273])

HSP 1 Score: 108.612 bits (270), Expect = 4.713e-26
Identity = 81/223 (36.32%), Postives = 112/223 (50.22%), Query Frame = 1 
Query:  874 HQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTG------QMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDSMDEMTEDQIDEDNCIKPKA----EMLLTSDPNNPRG-DSSDIPTETSEASSPVLKQQQTVTSI-----------PSSGSPNN 1476
            +  YPT+S N  +  SM           ++P G      +  P      I    + + + KGKK+RKPRTIY+S QLQ L K+FQ+TQYL+LP+RA LA  LGL+QTQVKIWFQNRRSK KK              +   S D  ++++ D+    KP++    E ++  + + PR   SS I TE  E   P+   +Q  +             PS G PNN
Sbjct:   38 YHAYPTSSTNGATGGSMYGTPQQTSAYAMYPPGPGSSPEEAFPEHTTTKIVEGCEAKYNVKGKKMRKPRTIYNSSQLQMLQKKFQKTQYLALPDRAALAHELGLSQTQVKIWFQNRRSKQKK--------------QKGGSSDHASDEEDDDTEESKPESPPMGESVMIQESSEPRTLVSSSIKTEMKEEYPPMTLNEQYASPYLYGSDFSTILPPSQGFPNN 246
[Close]
BLAST of distal-less vs. Ensembl Celegans
Match: ceh-43 (Homeobox protein ceh-43 [Source:UniProtKB/Swiss-Prot;Acc:Q18273])

HSP 1 Score: 100.523 bits (249), Expect = 3.343e-23
Identity = 81/232 (34.91%), Postives = 112/232 (48.28%), Query Frame = 1 
Query:  874 HQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTG------QMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQT---------QVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDSMDEMTEDQIDEDNCIKPKA----EMLLTSDPNNPRG-DSSDIPTETSEASSPVLKQQQTVTSI-----------PSSGSPNN 1476
            +  YPT+S N  +  SM           ++P G      +  P      I    + + + KGKK+RKPRTIY+S QLQ L K+FQ+TQYL+LP+RA LA  LGL+QT         QVKIWFQNRRSK KK              +   S D  ++++ D+    KP++    E ++  + + PR   SS I TE  E   P+   +Q  +             PS G PNN
Sbjct:   38 YHAYPTSSTNGATGGSMYGTPQQTSAYAMYPPGPGSSPEEAFPEHTTTKIVEGCEAKYNVKGKKMRKPRTIYNSSQLQMLQKKFQKTQYLALPDRAALAHELGLSQTQRAQPITEFQVKIWFQNRRSKQKK--------------QKGGSSDHASDEEDDDTEESKPESPPMGESVMIQESSEPRTLVSSSIKTEMKEEYPPMTLNEQYASPYLYGSDFSTILPPSQGFPNN 255
[Close]
BLAST of distal-less vs. Ensembl Celegans
Match: tab-1 (pep chromosome:WBcel235:II:6803758:6804761:1 gene:WBGene00006380.1 transcript:F31E8.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tab-1)

HSP 1 Score: 88.9669 bits (219), Expect = 3.779e-20
Identity = 50/125 (40.00%), Postives = 73/125 (58.40%), Query Frame = 1 
Query:  922 MAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIR------KPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDS 1278
            +AAA +  +H+++        P         DQIR+S   K  R      K RT++S  QLQ L +RF+  +YLS PER ELA++L L++TQVK WFQNRR K+KK++++  +     NG  N+S
Sbjct:   72 LAAAAFPIEHSLLLAQRNGVFPGF---WSTADQIRLSNATKAYRRLSSRRKARTVFSDQQLQGLERRFESQRYLSTPERIELANALNLSETQVKTWFQNRRMKHKKVVRKDDNSVDDDNGNDNES 193
[Close]
BLAST of distal-less vs. Ensembl Celegans
Match: tab-1 (pep chromosome:WBcel235:II:6803758:6804863:1 gene:WBGene00006380.1 transcript:F31E8.3a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tab-1)

HSP 1 Score: 87.8113 bits (216), Expect = 1.079e-19
Identity = 50/128 (39.06%), Postives = 73/128 (57.03%), Query Frame = 1 
Query:  922 MAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIR---------KPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDS 1278
            +AAA +  +H+++        P         DQIR+S   K  R         K RT++S  QLQ L +RF+  +YLS PER ELA++L L++TQVK WFQNRR K+KK++++  +     NG  N+S
Sbjct:   72 LAAAAFPIEHSLLLAQRNGVFPGF---WSTADQIRLSNATKAYRRLRLECSRRKARTVFSDQQLQGLERRFESQRYLSTPERIELANALNLSETQVKTWFQNRRMKHKKVVRKDDNSVDDDNGNDNES 196
[Close]
BLAST of distal-less vs. Ensembl Celegans
Match: vab-15 (Homeobox protein vab-15 [Source:UniProtKB/Swiss-Prot;Acc:Q09604])

HSP 1 Score: 81.6481 bits (200), Expect = 2.656e-17
Identity = 48/113 (42.48%), Postives = 69/113 (61.06%), Query Frame = 1 
Query:  910 SSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVS--------GKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKL 1224
            S +S A++  + QH++ + + Q      +ED    D  ++          K K  RKPRT +S+ QL  L ++FQ  QYLS+ ERAE ++SL LT+TQVKIWFQNRR+K K+L
Sbjct:   81 SPESCASSPLSMQHSLQWLSSQ------REDSPTSDDAKIQIGLSKCMLRKHKNNRKPRTPFSTQQLISLERKFQSKQYLSIAERAEFSASLQLTETQVKIWFQNRRAKSKRL 187
[Close]
BLAST of distal-less vs. Ensembl Fly
Match: Dll (gene:FBgn0000157 transcript:FBtr0072379)

HSP 1 Score: 139.043 bits (349), Expect = 3.802e-36
Identity = 69/100 (69.00%), Postives = 80/100 (80.00%), Query Frame = 1 
Query:  970 GQMTPPSM---KEDIQREDQ-----IRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            G   PP     K+D    D+     +RV+GKGKK+RKPRTIYSSLQLQQL++RFQRTQYL+LPERAELA+SLGLTQTQVKIWFQNRRSKYKK++K  Q P
Sbjct:   90 GSYAPPCASPPKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGP 189
[Close]
BLAST of distal-less vs. Ensembl Fly
Match: Dll (gene:FBgn0000157 transcript:FBtr0072378)

HSP 1 Score: 139.043 bits (349), Expect = 3.899e-36
Identity = 69/100 (69.00%), Postives = 80/100 (80.00%), Query Frame = 1 
Query:  970 GQMTPPSM---KEDIQREDQ-----IRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            G   PP     K+D    D+     +RV+GKGKK+RKPRTIYSSLQLQQL++RFQRTQYL+LPERAELA+SLGLTQTQVKIWFQNRRSKYKK++K  Q P
Sbjct:   90 GSYAPPCASPPKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGP 189
[Close]
BLAST of distal-less vs. Ensembl Fly
Match: Dll (gene:FBgn0000157 transcript:FBtr0300076)

HSP 1 Score: 139.428 bits (350), Expect = 4.924e-36
Identity = 69/100 (69.00%), Postives = 80/100 (80.00%), Query Frame = 1 
Query:  970 GQMTPPSM---KEDIQREDQ-----IRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            G   PP     K+D    D+     +RV+GKGKK+RKPRTIYSSLQLQQL++RFQRTQYL+LPERAELA+SLGLTQTQVKIWFQNRRSKYKK++K  Q P
Sbjct:   90 GSYAPPCASPPKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGP 189
[Close]
BLAST of distal-less vs. Ensembl Fly
Match: bsh (gene:FBgn0000529 transcript:FBtr0343855)

HSP 1 Score: 85.1149 bits (209), Expect = 3.636e-17
Identity = 36/63 (57.14%), Postives = 49/63 (77.78%), Query Frame = 1 
Query: 1045 KIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQ 1233
            + RK RT++S  QL  L KRF+  +YLS PER ELA++LGL++TQVK WFQNRR K+KK +++
Sbjct:  273 RRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLRR 335
[Close]
BLAST of distal-less vs. Ensembl Fly
Match: bsh (gene:FBgn0000529 transcript:FBtr0089320)

HSP 1 Score: 85.1149 bits (209), Expect = 3.636e-17
Identity = 36/63 (57.14%), Postives = 49/63 (77.78%), Query Frame = 1 
Query: 1045 KIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQ 1233
            + RK RT++S  QL  L KRF+  +YLS PER ELA++LGL++TQVK WFQNRR K+KK +++
Sbjct:  273 RRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLRR 335
[Close]
BLAST of distal-less vs. Ensembl Zebrafish
Match: dlx1a (distal-less homeobox 1a [Source:NCBI gene;Acc:30568])

HSP 1 Score: 137.887 bits (346), Expect = 2.199e-36
Identity = 67/98 (68.37%), Postives = 80/98 (81.63%), Query Frame = 1 
Query:  982 PPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQ---DPSILMNGE 1266
            P S K  +    ++R +GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG    D + L NG 
Sbjct:  106 PESEKNTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGGTIDTNALANGR 203
[Close]
BLAST of distal-less vs. Ensembl Zebrafish
Match: dlx6a (distal-less homeobox 6a [Source:NCBI gene;Acc:30586])

HSP 1 Score: 132.494 bits (332), Expect = 9.823e-36
Identity = 63/84 (75.00%), Postives = 74/84 (88.10%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            K  +    +IR +GKGKKIRKPRTIYSSLQLQ L+ RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG +P
Sbjct:    6 KTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGGNP 89
[Close]
BLAST of distal-less vs. Ensembl Zebrafish
Match: dlx6a (distal-less homeobox 6a [Source:NCBI gene;Acc:30586])

HSP 1 Score: 135.961 bits (341), Expect = 1.127e-35
Identity = 63/84 (75.00%), Postives = 74/84 (88.10%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            K  +    +IR +GKGKKIRKPRTIYSSLQLQ L+ RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG +P
Sbjct:  107 KTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGGNP 190
[Close]
BLAST of distal-less vs. Ensembl Zebrafish
Match: dlx6a (distal-less homeobox 6a [Source:NCBI gene;Acc:30586])

HSP 1 Score: 132.494 bits (332), Expect = 1.907e-35
Identity = 63/84 (75.00%), Postives = 74/84 (88.10%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            K  +    +IR +GKGKKIRKPRTIYSSLQLQ L+ RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG +P
Sbjct:   30 KTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGGNP 113
[Close]
BLAST of distal-less vs. Ensembl Zebrafish
Match: dlx4a (distal-less homeobox 4a [Source:NCBI gene;Acc:30561])

HSP 1 Score: 133.265 bits (334), Expect = 9.616e-35
Identity = 66/115 (57.39%), Postives = 86/115 (74.78%), Query Frame = 1 
Query:  895 SHNYMSSQSMAAAVYNYQHNMVFPTGQMTPP-SMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQG 1236
            +++Y ++     A   YQHN      ++    S K+      +IR++GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERA+LA+ LGLTQTQVKIWFQN+RSKYKK++K G
Sbjct:   71 AYHYSTAHHHPGAYLPYQHNSAVGYSRVEDADSEKQSSIESGEIRLNGKGKKIRKPRTIYSSLQLQALNQRFQQTQYLALPERADLAAKLGLTQTQVKIWFQNKRSKYKKIMKHG 185
[Close]
BLAST of distal-less vs. Ensembl Xenopus
Match: shpk (sedoheptulokinase [Source:Xenbase;Acc:XB-GENE-991309])

HSP 1 Score: 137.117 bits (344), Expect = 7.458e-36
Identity = 64/84 (76.19%), Postives = 74/84 (88.10%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            K  +    +IR +GKGKKIRKPRTIYSSLQLQ L+ RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSKYKKL+KQG +P
Sbjct:  116 KTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKYKKLLKQGSNP 199
[Close]
BLAST of distal-less vs. Ensembl Xenopus
Match: dlx1 (distal-less homeobox 1 [Source:NCBI gene;Acc:100101750])

HSP 1 Score: 135.191 bits (339), Expect = 3.481e-35
Identity = 65/94 (69.15%), Postives = 78/94 (82.98%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQ---DPSILMNGE 1266
            K  +    ++R +GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG    + S L NG 
Sbjct:  106 KSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALESSALANGR 199
[Close]
BLAST of distal-less vs. Ensembl Xenopus
Match: ENSXETT00000050197.1 (distal-less homeobox 4 [Source:NCBI gene;Acc:100494171])

HSP 1 Score: 131.724 bits (330), Expect = 5.043e-34
Identity = 60/81 (74.07%), Postives = 72/81 (88.89%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQG 1236
            K  +    +IR++GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERAELA+ LGLTQTQVKIWFQN+RSKYKK++K G
Sbjct:  112 KSTVIENGEIRINGKGKKIRKPRTIYSSLQLQALNQRFQQTQYLALPERAELAAQLGLTQTQVKIWFQNKRSKYKKVMKHG 192
[Close]
BLAST of distal-less vs. Ensembl Xenopus
Match: dlx1 (distal-less homeobox 1 [Source:NCBI gene;Acc:100101750])

HSP 1 Score: 134.806 bits (338), Expect = 1.562e-33
Identity = 65/94 (69.15%), Postives = 78/94 (82.98%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQ---DPSILMNGE 1266
            K  +    ++R +GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG    + S L NG 
Sbjct:  278 KSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALESSALANGR 371
[Close]
BLAST of distal-less vs. Ensembl Xenopus
Match: dlx2 (distal-less homeobox 2 [Source:NCBI gene;Acc:493423])

HSP 1 Score: 129.413 bits (324), Expect = 7.911e-33
Identity = 61/85 (71.76%), Postives = 73/85 (85.88%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPS 1248
            KED + E ++ V+GK KK+RKPRTIYSS QL  L +RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQNRRSK+KK+ K G+ PS
Sbjct:  110 KEDCEPEVRM-VNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPS 193
[Close]
BLAST of distal-less vs. Ensembl Mouse
Match: Dlx1 (distal-less homeobox 1 [Source:MGI Symbol;Acc:MGI:94901])

HSP 1 Score: 137.117 bits (344), Expect = 5.427e-36
Identity = 79/154 (51.30%), Postives = 99/154 (64.29%), Query Frame = 1 
Query:  814 ARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQ---DPSILMNGE 1266
            A +F+ P G     S   H    Y ++  +Y  S S+A      Q  +  P       S K  +    ++R +GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG    + S L NG 
Sbjct:   60 ASSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLA------QSRLEDPGAD----SEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGR 203
[Close]
BLAST of distal-less vs. Ensembl Mouse
Match: Dlx6 (distal-less homeobox 6 [Source:MGI Symbol;Acc:MGI:101927])

HSP 1 Score: 133.265 bits (334), Expect = 9.246e-36
Identity = 63/84 (75.00%), Postives = 74/84 (88.10%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            K  +    +IR +GKGKKIRKPRTIYSSLQLQ L+ RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG +P
Sbjct:   14 KTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNP 97
[Close]
BLAST of distal-less vs. Ensembl Mouse
Match: Dlx6 (distal-less homeobox 6 [Source:MGI Symbol;Acc:MGI:101927])

HSP 1 Score: 136.732 bits (343), Expect = 2.360e-35
Identity = 63/84 (75.00%), Postives = 74/84 (88.10%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            K  +    +IR +GKGKKIRKPRTIYSSLQLQ L+ RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG +P
Sbjct:  153 KTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNP 236
[Close]
BLAST of distal-less vs. Ensembl Mouse
Match: Dlx6 (distal-less homeobox 6 [Source:MGI Symbol;Acc:MGI:101927])

HSP 1 Score: 136.732 bits (343), Expect = 2.360e-35
Identity = 63/84 (75.00%), Postives = 74/84 (88.10%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            K  +    +IR +GKGKKIRKPRTIYSSLQLQ L+ RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG +P
Sbjct:  153 KTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNP 236
[Close]
BLAST of distal-less vs. Ensembl Mouse
Match: Dlx2 (distal-less homeobox 2 [Source:MGI Symbol;Acc:MGI:94902])

HSP 1 Score: 131.339 bits (329), Expect = 3.255e-33
Identity = 61/85 (71.76%), Postives = 74/85 (87.06%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPS 1248
            KED++ E +I V+GK KK+RKPRTIYSS QL  L +RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQNRRSK+KK+ K G+ P+
Sbjct:  138 KEDLEPEIRI-VNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPT 221
[Close]
BLAST of distal-less vs. UniProt/SwissProt
Match: sp|P53773|DLL1_XENLA (Homeobox protein DLL-1 OS=Xenopus laevis OX=8355 GN=dll1 PE=2 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 8.127e-36
Identity = 65/88 (73.86%), Postives = 75/88 (85.23%), Query Frame = 1 
Query:  982 PPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            P   K  +    +IR +GKGKKIRKPRTIYSSLQLQ L+ RFQ+TQYL+LPERAELA+SLG+TQTQVKIWFQN+RSKYKKLIKQG +P
Sbjct:  103 PDQQKTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGVTQTQVKIWFQNKRSKYKKLIKQGNNP 190
[Close]
BLAST of distal-less vs. UniProt/SwissProt
Match: sp|Q98875|DLX1A_DANRE (Homeobox protein Dlx1a OS=Danio rerio OX=7955 GN=dlx1a PE=2 SV=1)

HSP 1 Score: 137.887 bits (346), Expect = 1.660e-35
Identity = 67/98 (68.37%), Postives = 80/98 (81.63%), Query Frame = 1 
Query:  982 PPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQ---DPSILMNGE 1266
            P S K  +    ++R +GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG    D + L NG 
Sbjct:  106 PESEKNTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGGTIDTNALANGR 203
[Close]
BLAST of distal-less vs. UniProt/SwissProt
Match: sp|P56177|DLX1_HUMAN (Homeobox protein DLX-1 OS=Homo sapiens OX=9606 GN=DLX1 PE=1 SV=3)

HSP 1 Score: 137.117 bits (344), Expect = 3.509e-35
Identity = 79/154 (51.30%), Postives = 99/154 (64.29%), Query Frame = 1 
Query:  814 ARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQ---DPSILMNGE 1266
            A +F+ P G     S   H    Y ++  +Y  S S+A      Q  +  P       S K  +    ++R +GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG    + S L NG 
Sbjct:   60 ASSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLA------QSRLEDPGAD----SEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGR 203
[Close]
BLAST of distal-less vs. UniProt/SwissProt
Match: sp|Q64317|DLX1_MOUSE (Homeobox protein DLX-1 OS=Mus musculus OX=10090 GN=Dlx1 PE=1 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 3.796e-35
Identity = 79/154 (51.30%), Postives = 99/154 (64.29%), Query Frame = 1 
Query:  814 ARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQ---DPSILMNGE 1266
            A +F+ P G     S   H    Y ++  +Y  S S+A      Q  +  P       S K  +    ++R +GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG    + S L NG 
Sbjct:   60 ASSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLA------QSRLEDPGAD----SEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGR 203
[Close]
BLAST of distal-less vs. UniProt/SwissProt
Match: sp|P20009|DLL_DROME (Homeotic protein distal-less OS=Drosophila melanogaster OX=7227 GN=Dll PE=2 SV=3)

HSP 1 Score: 139.043 bits (349), Expect = 3.811e-35
Identity = 69/100 (69.00%), Postives = 80/100 (80.00%), Query Frame = 1 
Query:  970 GQMTPPSM---KEDIQREDQ-----IRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            G   PP     K+D    D+     +RV+GKGKK+RKPRTIYSSLQLQQL++RFQRTQYL+LPERAELA+SLGLTQTQVKIWFQNRRSKYKK++K  Q P
Sbjct:   90 GSYAPPCASPPKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGP 189
[Close]
BLAST of distal-less vs. TrEMBL
Match: H9B8J6 (Distal-less OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 941.799 bits (2433), Expect = 0.000e+0
Identity = 476/476 (100.00%), Postives = 476/476 (100.00%), Query Frame = 1 
Query:  340 MDNGLFSSALXXXXXXXXXXXXQGLLPPFGLSKLDPQSFYGFPNQYDMLYPNMSTRLYAASDNCNEPNLSLTKTSIFSNSSNLAYSSLGCDNLPVSSPTDILQDGFGGINSHKKDLHSISGLGISTSNNQQLMPPLSTPGYRNINQQLNPGTNSSVILARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDSMDEMTEDQIDEDNCIKPKAEMLLTSDPNNPRGDSSDIPTETSEASSPVLKQQQTVTSIPSSGSPNNKYSLDGGLVSHYHGAIDPYPSQLTNPHQLSYYTNNMNNSQLPLGTSGFIDSSYLGMGQSMNHLTAQSGYQYYLNPYNTNSYPTWYSSECLLNNVDFK 1767
            MDNGLFSSALPDSPSKSDIKPPQGLLPPFGLSKLDPQSFYGFPNQYDMLYPNMSTRLYAASDNCNEPNLSLTKTSIFSNSSNLAYSSLGCDNLPVSSPTDILQDGFGGINSHKKDLHSISGLGISTSNNQQLMPPLSTPGYRNINQQLNPGTNSSVILARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDSMDEMTEDQIDEDNCIKPKAEMLLTSDPNNPRGDSSDIPTETSEASSPVLKQQQTVTSIPSSGSPNNKYSLDGGLVSHYHGAIDPYPSQLTNPHQLSYYTNNMNNSQLPLGTSGFIDSSYLGMGQSMNHLTAQSGYQYYLNPYNTNSYPTWYSSECLLNNVDFK
Sbjct:    1 MDNGLFSSALPDSPSKSDIKPPQGLLPPFGLSKLDPQSFYGFPNQYDMLYPNMSTRLYAASDNCNEPNLSLTKTSIFSNSSNLAYSSLGCDNLPVSSPTDILQDGFGGINSHKKDLHSISGLGISTSNNQQLMPPLSTPGYRNINQQLNPGTNSSVILARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDSMDEMTEDQIDEDNCIKPKAEMLLTSDPNNPRGDSSDIPTETSEASSPVLKQQQTVTSIPSSGSPNNKYSLDGGLVSHYHGAIDPYPSQLTNPHQLSYYTNNMNNSQLPLGTSGFIDSSYLGMGQSMNHLTAQSGYQYYLNPYNTNSYPTWYSSECLLNNVDFK 476
[Close]
BLAST of distal-less vs. TrEMBL
Match: T1D154 (Dlx (Fragment) OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 290.812 bits (743), Expect = 5.711e-91
Identity = 148/208 (71.15%), Postives = 173/208 (83.17%), Query Frame = 1 
Query: 1147 LASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDSMDEMTEDQIDEDNCIKPKAEMLLTSDPNNPRGDSSDIPTETSEASSPVLKQQQTVTSIPSSGSPNNKYSLDGGLVSHYHGAIDPYPSQLTNPHQLSYYTNNMNNSQLPLGTSGFIDSSYLGMGQSMNHLTAQSGYQYYLNPYNTNSYPTWYSSEC-LLNNVDFK 1767
            LA+ + L  TQVKIWFQNRRSKYKKLIKQGQDPSILMNG+FNDSMDEMTEDQ+DE+NCIKPK EM+LTS P+N RGD S+ PTETSEASSP +KQ Q++TSI +  SPNNKYSLD  +VSHYHG ++ YP+QL N H ++YY N +NNSQL LG+  FIDS+YL M Q++N L +QSGYQYYLN YN+NSYP WY SEC LLNN DFK
Sbjct:    1 LANLINLPPTQVKIWFQNRRSKYKKLIKQGQDPSILMNGDFNDSMDEMTEDQVDEENCIKPKVEMILTSVPSNQRGDGSENPTETSEASSPNIKQHQSITSISTGESPNNKYSLDTSIVSHYHGGLESYPAQLANQHHITYYNNALNNSQLHLGSGSFIDSNYLNMSQTVNPLASQSGYQYYLNNYNSNSYPNWYPSECSLLNNADFK 208
[Close]
BLAST of distal-less vs. TrEMBL
Match: A0A2Z5VI94 (Homeobox protein Dlx (Fragment) OS=Nipponacmea fuscoviridis OX=225302 GN=dlx PE=2 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 1.251e-36
Identity = 86/150 (57.33%), Postives = 102/150 (68.00%), Query Frame = 1 
Query:  814 ARNFNSPYGTQQSTSALGHLHQNYPTNSHNY-----MSSQSMAAAVYNY---QHNMVFPTGQMTPPSMKED--IQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQ 1233
            A N  S Y TQ S       H  +PT+ H           SMA + YN     H+  FP     PPS   D   Q E+Q+R++GKGKK+RKPRTIYSSLQLQQL++RFQRTQYL+LPERAELA+SLGLTQTQVKIWFQN+RSKYKK++KQ
Sbjct:   14 AYNIRSGYPTQHSQ------HDMFPTSQHTRSFGYPFPMNSMAPSGYNAVPPSHH--FPMSPYQPPSPTRDDKSQVEEQLRINGKGKKLRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNKRSKYKKVMKQ 155
[Close]
BLAST of distal-less vs. TrEMBL
Match: E1UGZ4 (Distal-less protein OS=Euperipatoides kanangrensis OX=488523 GN=dll PE=2 SV=1)

HSP 1 Score: 147.517 bits (371), Expect = 2.522e-36
Identity = 91/181 (50.28%), Postives = 109/181 (60.22%), Query Frame = 1 
Query:  688 HSISGLGISTSNNQQLMPPLSTPGYRNINQQLNPGTNSSVILARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIK 1230
            H +S        NQQ M  ++ P    I         SS       +S + T QS+ ALG  H  YP N+    +  S         H  V P  Q   P   E  Q ++ +RV+GKGKK+RKPRTIYSSLQLQQL++RFQRTQYL+LPERAELA+SLGLTQTQVKIWFQNRRSKYKKL+K
Sbjct:   10 HEVSSKSAFMELNQQGMTGMTHPAAYPIR--------SSYSQPSQHDSAFSTTQSSRALGSYH--YPLNTRPSYTHPS---------HTFVNPY-QCASPQRDEKTQMDETLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKLMK 170
[Close]
BLAST of distal-less vs. TrEMBL
Match: A0A1S3I8F2 (homeobox protein Dlx1a isoform X2 OS=Lingula unguis OX=7574 GN=LOC106162000 PE=4 SV=1)

HSP 1 Score: 148.288 bits (373), Expect = 4.734e-36
Identity = 68/90 (75.56%), Postives = 82/90 (91.11%), Query Frame = 1 
Query:  973 QMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQD 1242
            Q  PP  +E   +E+Q+R++GKGKK+RKPRTIYSSLQLQQL++RFQRTQYL+LPERAELA+SLGLTQTQVKIWFQNRRSKYKK++KQ Q+
Sbjct:   95 QTPPPVREEGKTQEEQLRMNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKIMKQQQN 184
[Close]
BLAST of distal-less vs. Ensembl Cavefish
Match: dlx1a (distal-less homeobox 1 [Source:NCBI gene;Acc:103031421])

HSP 1 Score: 140.198 bits (352), Expect = 3.771e-37
Identity = 76/135 (56.30%), Postives = 93/135 (68.89%), Query Frame = 1 
Query:  883 YP-TNSHNYMSSQSMAAAVYNYQHNMVFPTGQM---TPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQG---QDPSILMNGE 1266
            YP  NS    SS      V  YQ++      ++    P + K  +    ++R +GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG    D S L NG 
Sbjct:   69 YPYVNSVGSHSSSPYLTTVQTYQNSTALTQTRLEDSAPEAEKNTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGGAMDTSALANGR 203
[Close]
BLAST of distal-less vs. Ensembl Cavefish
Match: dlx6a (distal-less homeobox 6 [Source:NCBI gene;Acc:103029558])

HSP 1 Score: 136.732 bits (343), Expect = 4.561e-36
Identity = 63/84 (75.00%), Postives = 74/84 (88.10%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            K  +    +IR +GKGKKIRKPRTIYSSLQLQ L+ RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG +P
Sbjct:  107 KTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNP 190
[Close]
BLAST of distal-less vs. Ensembl Cavefish
Match: dlx2 (distal-less homeobox 2 [Source:NCBI gene;Acc:103031105])

HSP 1 Score: 130.568 bits (327), Expect = 1.574e-33
Identity = 62/88 (70.45%), Postives = 73/88 (82.95%), Query Frame = 1 
Query:  985 PSMKEDIQREDQIR-VSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            P+  E  + E +IR V+GK KK+RKPRTIYSS QL  L +RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQNRRSK+KKL K G+ P
Sbjct:  103 PADAEKEESEPEIRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKLWKNGEIP 190
[Close]
BLAST of distal-less vs. Ensembl Cavefish
Match: ENSAMXT00000042049.1 (homeobox protein Dlx4a-like [Source:NCBI gene;Acc:111191376])

HSP 1 Score: 129.028 bits (323), Expect = 1.623e-33
Identity = 58/81 (71.60%), Postives = 71/81 (87.65%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQG 1236
            K  +    +IR++GKGKKIRKPRTIYSS QLQ L++RFQ+TQYL+LPERA+LA+ LGLTQTQVKIWFQN+RSKYKK++K G
Sbjct:   83 KSAVIENGEIRLNGKGKKIRKPRTIYSSFQLQALNQRFQQTQYLALPERADLAAKLGLTQTQVKIWFQNKRSKYKKIMKHG 163
[Close]
BLAST of distal-less vs. Ensembl Cavefish
Match: dlx2b (Astyanax mexicanus homeobox protein Dlx2b-like (LOC103034899), mRNA. [Source:RefSeq mRNA;Acc:NM_001291254])

HSP 1 Score: 130.183 bits (326), Expect = 2.006e-33
Identity = 61/89 (68.54%), Postives = 74/89 (83.15%), Query Frame = 1 
Query:  985 PSMKEDIQREDQIR-VSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPS 1248
            P+  E  + E ++R V+GK KK+RKPRTIYSS QL  L +RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQNRRSK+KKL K G+ P+
Sbjct:  103 PTEPEKDESEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKLWKNGEIPT 191
[Close]
BLAST of distal-less vs. Ensembl Sea Lamprey
Match: dlx5a (distal-less homeobox 5a [Source:NCBI gene;Acc:30569])

HSP 1 Score: 123.635 bits (309), Expect = 9.311e-31
Identity = 59/78 (75.64%), Postives = 68/78 (87.18%), Query Frame = 1 
Query: 1009 REDQIR-VSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQ 1239
            R+  +R V+GK KKIRKPRTIYSS QL  L +RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQNRRSK+KKL K G+
Sbjct:  188 RQSGVRMVNGKPKKIRKPRTIYSSFQLAALQRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKLGKNGE 265
[Close]
BLAST of distal-less vs. Ensembl Sea Lamprey
Match: dlx6a (distal-less homeobox 6a [Source:NCBI gene;Acc:30586])

HSP 1 Score: 96.6709 bits (239), Expect = 7.347e-24
Identity = 46/64 (71.88%), Postives = 57/64 (89.06%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVK 1185
            K  + +  ++R +GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERAELA+SLGLTQTQV+
Sbjct:   84 KTPVIQNGELRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVR 147
[Close]
BLAST of distal-less vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001141.1 (pep scaffold:Pmarinus_7.0:GL478075:36995:38394:-1 gene:ENSPMAG00000001023.1 transcript:ENSPMAT00000001141.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 75.0998 bits (183), Expect = 7.873e-17
Identity = 35/59 (59.32%), Postives = 47/59 (79.66%), Query Frame = 1 
Query: 1045 KIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKK 1221
            K R+PRT +SS QL +L + F R +YLS P+R ++AS+L LT+TQVKIWFQNRR K+K+
Sbjct:    2 KCRRPRTAFSSQQLLELERHFSRQRYLSRPQRFQVASALMLTETQVKIWFQNRRMKWKR 60
[Close]
BLAST of distal-less vs. Ensembl Sea Lamprey
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 74.3294 bits (181), Expect = 1.998e-16
Identity = 35/62 (56.45%), Postives = 47/62 (75.81%), Query Frame = 1 
Query: 1036 KGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKK 1221
            + KK RK RT +S  QL QL + F+R +YLS+ +R ELASSL L+ TQVK W+QNRR+K+K+
Sbjct:    1 RAKKPRKARTAFSDHQLTQLERSFERQKYLSVQDRMELASSLSLSDTQVKTWYQNRRTKWKR 62
[Close]
BLAST of distal-less vs. Ensembl Sea Lamprey
Match: MSX1 (msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391])

HSP 1 Score: 75.485 bits (184), Expect = 2.008e-16
Identity = 37/63 (58.73%), Postives = 49/63 (77.78%), Query Frame = 1 
Query: 1036 KGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKL 1224
            K K  RKPRT +++ QL  L  +F++ QYLS+ ERAE ++SL LT+TQVKIWFQNRR+K K+L
Sbjct:   10 KHKATRKPRTPFTTSQLLALEHKFRQKQYLSIAERAEFSTSLSLTETQVKIWFQNRRAKAKRL 72
[Close]
BLAST of distal-less vs. Ensembl Yeast
Match: PHO2 (Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002264])

HSP 1 Score: 47.3654 bits (111), Expect = 5.504e-6
Identity = 21/57 (36.84%), Postives = 33/57 (57.89%), Query Frame = 1 
Query: 1051 RKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKK 1221
            R  RT      L  L ++F+     SL ER +++  +G+ +  V+IWFQNRR+K +K
Sbjct:   78 RPKRTRAKGEALDVLKRKFEINPTPSLVERKKISDLIGMPEKNVRIWFQNRRAKLRK 134
[Close]
BLAST of distal-less vs. Ensembl Nematostella
Match: EDO46555 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPR7])

HSP 1 Score: 115.161 bits (287), Expect = 4.569e-31
Identity = 54/69 (78.26%), Postives = 65/69 (94.20%), Query Frame = 1 
Query: 1024 RVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIK 1230
            R++GKGKKIRKPRTIYSS QL++L+KRF +TQYL+LPERA+LA+ LGLTQTQVKIWFQNRRSK+KK +K
Sbjct:    3 RLNGKGKKIRKPRTIYSSFQLRELNKRFIKTQYLALPERADLAAYLGLTQTQVKIWFQNRRSKFKKTLK 71
[Close]
BLAST of distal-less vs. Ensembl Nematostella
Match: MSX (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI73])

HSP 1 Score: 77.411 bits (189), Expect = 1.744e-17
Identity = 37/63 (58.73%), Postives = 50/63 (79.37%), Query Frame = 1 
Query: 1036 KGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKL 1224
            K K  RKPRT +++ QL  L ++F++ QYLS+ ERAE ++SL LT+TQVKIWFQNRR+K K+L
Sbjct:   10 KHKANRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSASLNLTETQVKIWFQNRRAKAKRL 72
[Close]
BLAST of distal-less vs. Ensembl Nematostella
Match: EDO42243 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S290])

HSP 1 Score: 75.8702 bits (185), Expect = 3.484e-17
Identity = 36/60 (60.00%), Postives = 47/60 (78.33%), Query Frame = 1 
Query: 1051 RKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIK 1230
            R+PRT +SS QL  L ++FQ  +YL+ P+R ELA+SL LT+TQVKIWFQNRR K+K+  K
Sbjct:    8 RRPRTAFSSHQLLALERQFQLHKYLTRPQRYELATSLMLTETQVKIWFQNRRMKWKRCNK 67
[Close]
BLAST of distal-less vs. Ensembl Nematostella
Match: EDO32495 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUX2])

HSP 1 Score: 73.1738 bits (178), Expect = 2.440e-16
Identity = 30/57 (52.63%), Postives = 47/57 (82.46%), Query Frame = 1 
Query: 1051 RKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKK 1221
            ++PRT +++ Q++ L   FQ+++YLS+  R ELA+SL LT+TQ+KIWFQNRR+K+K+
Sbjct:    2 KRPRTAFTNEQIKDLEAEFQKSKYLSVSRRMELANSLSLTETQIKIWFQNRRTKWKR 58
[Close]
BLAST of distal-less vs. Ensembl Nematostella
Match: EDO35073 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMK0])

HSP 1 Score: 73.559 bits (179), Expect = 2.741e-16
Identity = 34/68 (50.00%), Postives = 48/68 (70.59%), Query Frame = 1 
Query: 1039 GKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQD 1242
            G++ RK RT+++ LQL+ L K F   +YL    R++LA +LGL +TQVK WFQNRR K+KK  + G+D
Sbjct:   13 GRRCRKSRTVFTDLQLRVLEKTFSEQKYLDTSSRSKLAQTLGLNETQVKTWFQNRRMKWKK--ETGKD 78
[Close]
BLAST of distal-less vs. Ensembl Medaka
Match: dlx1a (distal-less homeobox 1 [Source:NCBI gene;Acc:101161018])

HSP 1 Score: 137.502 bits (345), Expect = 2.820e-36
Identity = 65/98 (66.33%), Postives = 80/98 (81.63%), Query Frame = 1 
Query:  982 PPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQ---DPSILMNGE 1266
            P + K  +    ++R +GKGKKIRKPRTIYSSLQLQ L++RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG    D ++L  G 
Sbjct:  105 PEAEKNTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGSTIDTNVLTTGR 202
[Close]
BLAST of distal-less vs. Ensembl Medaka
Match: dlx6a (distal-less homeobox 6 [Source:NCBI gene;Acc:101158118])

HSP 1 Score: 136.346 bits (342), Expect = 6.236e-36
Identity = 63/84 (75.00%), Postives = 74/84 (88.10%), Query Frame = 1 
Query:  994 KEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            K  +    +IR +GKGKKIRKPRTIYSSLQLQ L+ RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQN+RSK+KKL+KQG +P
Sbjct:  106 KTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNP 189
[Close]
BLAST of distal-less vs. Ensembl Medaka
Match: dlx2 (distal-less homeobox 2 [Source:NCBI gene;Acc:100049449])

HSP 1 Score: 132.494 bits (332), Expect = 3.247e-34
Identity = 63/90 (70.00%), Postives = 74/90 (82.22%), Query Frame = 1 
Query:  979 TPPSMKEDIQREDQIR-VSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            TPP+  E  + E +IR V+GK KK+RKPRTIYSS QL  L +RFQ+TQYL+LPERAELA+SLGLTQTQVKIWFQNRRSK+KK  K G+ P
Sbjct:  102 TPPADNEKEESEPEIRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKQWKSGEIP 191
[Close]
BLAST of distal-less vs. Ensembl Medaka
Match: dlx4b (homeobox protein Dlx4b [Source:NCBI gene;Acc:101157253])

HSP 1 Score: 125.946 bits (315), Expect = 3.780e-32
Identity = 58/77 (75.32%), Postives = 68/77 (88.31%), Query Frame = 1 
Query: 1003 IQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQ 1233
            I+  D   V+GKGKKIRKPRTIYSSLQLQ L +RFQ+TQYL+LPERA+LA+ LGLTQTQVKIWFQN+RSKYKK++K 
Sbjct:  116 IESRDIRLVNGKGKKIRKPRTIYSSLQLQALHQRFQQTQYLALPERADLAAKLGLTQTQVKIWFQNKRSKYKKIMKH 192
[Close]
BLAST of distal-less vs. Ensembl Medaka
Match: dlx3b (distal-less homeobox 3 [Source:NCBI gene;Acc:101157491])

HSP 1 Score: 125.946 bits (315), Expect = 6.845e-32
Identity = 63/92 (68.48%), Postives = 76/92 (82.61%), Query Frame = 1 
Query:  973 QMTPP-SMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDP 1245
            Q +PP S+KE+ + E ++ V+GK KKIRKPRTIYSS QL  L +RFQ+ QYL+LPERAELA+ LGLTQTQVKIWFQNRRSK+KKL K G+ P
Sbjct:  106 QASPPGSVKEEPEPEVRM-VNGKPKKIRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVP 196
[Close]
BLAST of distal-less vs. Planmine SMEST
Match: SMESG000045025.1 (SMESG000045025.1)

HSP 1 Score: 1033.48 bits (2671), Expect = 0.000e+0
Identity = 521/521 (100.00%), Postives = 521/521 (100.00%), Query Frame = 1 
Query:  205 MISTMPHCNLQASNDLFEPPTASTGSETQSHSLQYPITSSGSYEFMDNGLFSSALXXXXXXXXXXXXQGLLPPFGLSKLDPQSFYGFPNQYDMLYPNMSTRLYAASDNCNEPNLSLTKTSIFSNSSNLAYSSLGCDNLPVSSPTDILQDGFGGINSHKKDLHSISGLGISTSNNQQLMPPLSTPGYRNINQQLNPGTNSSVILARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDSMDEMTEDQIDEDNCIKPKAEMLLTSDPNNPRGDSSDIPTETSEASSPVLKQQQTVTSIPSSGSPNNKYSLDGGLVSHYHGAIDPYPSQLTNPHQLSYYTNNMNNSQLPLGTSGFIDSSYLGMGQSMNHLTAQSGYQYYLNPYNTNSYPTWYSSECLLNNVDFK 1767
            MISTMPHCNLQASNDLFEPPTASTGSETQSHSLQYPITSSGSYEFMDNGLFSSALPDSPSKSDIKPPQGLLPPFGLSKLDPQSFYGFPNQYDMLYPNMSTRLYAASDNCNEPNLSLTKTSIFSNSSNLAYSSLGCDNLPVSSPTDILQDGFGGINSHKKDLHSISGLGISTSNNQQLMPPLSTPGYRNINQQLNPGTNSSVILARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDSMDEMTEDQIDEDNCIKPKAEMLLTSDPNNPRGDSSDIPTETSEASSPVLKQQQTVTSIPSSGSPNNKYSLDGGLVSHYHGAIDPYPSQLTNPHQLSYYTNNMNNSQLPLGTSGFIDSSYLGMGQSMNHLTAQSGYQYYLNPYNTNSYPTWYSSECLLNNVDFK
Sbjct:    1 MISTMPHCNLQASNDLFEPPTASTGSETQSHSLQYPITSSGSYEFMDNGLFSSALPDSPSKSDIKPPQGLLPPFGLSKLDPQSFYGFPNQYDMLYPNMSTRLYAASDNCNEPNLSLTKTSIFSNSSNLAYSSLGCDNLPVSSPTDILQDGFGGINSHKKDLHSISGLGISTSNNQQLMPPLSTPGYRNINQQLNPGTNSSVILARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDSMDEMTEDQIDEDNCIKPKAEMLLTSDPNNPRGDSSDIPTETSEASSPVLKQQQTVTSIPSSGSPNNKYSLDGGLVSHYHGAIDPYPSQLTNPHQLSYYTNNMNNSQLPLGTSGFIDSSYLGMGQSMNHLTAQSGYQYYLNPYNTNSYPTWYSSECLLNNVDFK 521
[Close]
BLAST of distal-less vs. Planmine SMEST
Match: SMESG000045025.1 (SMESG000045025.1)

HSP 1 Score: 1025 bits (2649), Expect = 0.000e+0
Identity = 517/517 (100.00%), Postives = 517/517 (100.00%), Query Frame = 1 
Query:  217 MPHCNLQASNDLFEPPTASTGSETQSHSLQYPITSSGSYEFMDNGLFSSALXXXXXXXXXXXXQGLLPPFGLSKLDPQSFYGFPNQYDMLYPNMSTRLYAASDNCNEPNLSLTKTSIFSNSSNLAYSSLGCDNLPVSSPTDILQDGFGGINSHKKDLHSISGLGISTSNNQQLMPPLSTPGYRNINQQLNPGTNSSVILARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDSMDEMTEDQIDEDNCIKPKAEMLLTSDPNNPRGDSSDIPTETSEASSPVLKQQQTVTSIPSSGSPNNKYSLDGGLVSHYHGAIDPYPSQLTNPHQLSYYTNNMNNSQLPLGTSGFIDSSYLGMGQSMNHLTAQSGYQYYLNPYNTNSYPTWYSSECLLNNVDFK 1767
            MPHCNLQASNDLFEPPTASTGSETQSHSLQYPITSSGSYEFMDNGLFSSALPDSPSKSDIKPPQGLLPPFGLSKLDPQSFYGFPNQYDMLYPNMSTRLYAASDNCNEPNLSLTKTSIFSNSSNLAYSSLGCDNLPVSSPTDILQDGFGGINSHKKDLHSISGLGISTSNNQQLMPPLSTPGYRNINQQLNPGTNSSVILARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDSMDEMTEDQIDEDNCIKPKAEMLLTSDPNNPRGDSSDIPTETSEASSPVLKQQQTVTSIPSSGSPNNKYSLDGGLVSHYHGAIDPYPSQLTNPHQLSYYTNNMNNSQLPLGTSGFIDSSYLGMGQSMNHLTAQSGYQYYLNPYNTNSYPTWYSSECLLNNVDFK
Sbjct:    1 MPHCNLQASNDLFEPPTASTGSETQSHSLQYPITSSGSYEFMDNGLFSSALPDSPSKSDIKPPQGLLPPFGLSKLDPQSFYGFPNQYDMLYPNMSTRLYAASDNCNEPNLSLTKTSIFSNSSNLAYSSLGCDNLPVSSPTDILQDGFGGINSHKKDLHSISGLGISTSNNQQLMPPLSTPGYRNINQQLNPGTNSSVILARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHNMVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDSMDEMTEDQIDEDNCIKPKAEMLLTSDPNNPRGDSSDIPTETSEASSPVLKQQQTVTSIPSSGSPNNKYSLDGGLVSHYHGAIDPYPSQLTNPHQLSYYTNNMNNSQLPLGTSGFIDSSYLGMGQSMNHLTAQSGYQYYLNPYNTNSYPTWYSSECLLNNVDFK 517
[Close]
BLAST of distal-less vs. Planmine SMEST
Match: SMESG000019757.1 (SMESG000019757.1)

HSP 1 Score: 84.3445 bits (207), Expect = 3.290e-18
Identity = 40/63 (63.49%), Postives = 50/63 (79.37%), Query Frame = 1 
Query: 1036 KGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKL 1224
            K K  RKPRT +++ QL QL K+F + QYLS+ ERAE +SSLGLT+ QVKIWFQNRR+K K+L
Sbjct:  105 KHKPNRKPRTPFTTQQLIQLEKKFHQKQYLSIAERAEFSSSLGLTEIQVKIWFQNRRAKSKRL 167
[Close]
BLAST of distal-less vs. Planmine SMEST
Match: SMESG000019757.1 (SMESG000019757.1)

HSP 1 Score: 84.3445 bits (207), Expect = 3.526e-18
Identity = 40/63 (63.49%), Postives = 50/63 (79.37%), Query Frame = 1 
Query: 1036 KGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKL 1224
            K K  RKPRT +++ QL QL K+F + QYLS+ ERAE +SSLGLT+ QVKIWFQNRR+K K+L
Sbjct:  101 KHKPNRKPRTPFTTQQLIQLEKKFHQKQYLSIAERAEFSSSLGLTEIQVKIWFQNRRAKSKRL 163
[Close]
BLAST of distal-less vs. Planmine SMEST
Match: SMESG000021901.1 (SMESG000021901.1)

HSP 1 Score: 83.9593 bits (206), Expect = 1.261e-17
Identity = 42/94 (44.68%), Postives = 66/94 (70.21%), Query Frame = 1 
Query: 1003 IQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKRFQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSILMNGEFNDSMD 1284
             +++ ++R S + KK +K RT +S  Q+ +L K+F+  +YLS  ERAELASSL +T+TQVKIWFQNRR+K+KK     ++ + ++  +F  S+D
Sbjct:  133 CEKKKRVRNSKQDKK-KKSRTTFSGRQICELEKQFELKKYLSSAERAELASSLNVTETQVKIWFQNRRTKWKK----QENITTVLAQQFRQSID 221
The following BLAST results are available for this feature:
BLAST of distal-less vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DLX17.306e-3651.30distal-less homeobox 1 [Source:HGNC Symbol;Acc:HGN... [more]
DLX69.900e-3675.00distal-less homeobox 6 [Source:HGNC Symbol;Acc:HGN... [more]
DLX64.035e-3575.00distal-less homeobox 6 [Source:HGNC Symbol;Acc:HGN... [more]
DLX15.244e-3452.17distal-less homeobox 1 [Source:HGNC Symbol;Acc:HGN... [more]
DLX22.169e-3372.94distal-less homeobox 2 [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of distal-less vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ceh-434.713e-2636.32Homeobox protein ceh-43 [Source:UniProtKB/Swiss-P... [more]
ceh-433.343e-2334.91Homeobox protein ceh-43 [Source:UniProtKB/Swiss-P... [more]
tab-13.779e-2040.00pep chromosome:WBcel235:II:6803758:6804761:1 gene:... [more]
tab-11.079e-1939.06pep chromosome:WBcel235:II:6803758:6804863:1 gene:... [more]
vab-152.656e-1742.48Homeobox protein vab-15 [Source:UniProtKB/Swiss-P... [more]
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BLAST of distal-less vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dll3.802e-3669.00gene:FBgn0000157 transcript:FBtr0072379[more]
Dll3.899e-3669.00gene:FBgn0000157 transcript:FBtr0072378[more]
Dll4.924e-3669.00gene:FBgn0000157 transcript:FBtr0300076[more]
bsh3.636e-1757.14gene:FBgn0000529 transcript:FBtr0343855[more]
bsh3.636e-1757.14gene:FBgn0000529 transcript:FBtr0089320[more]
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BLAST of distal-less vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dlx1a2.199e-3668.37distal-less homeobox 1a [Source:NCBI gene;Acc:3056... [more]
dlx6a9.823e-3675.00distal-less homeobox 6a [Source:NCBI gene;Acc:3058... [more]
dlx6a1.127e-3575.00distal-less homeobox 6a [Source:NCBI gene;Acc:3058... [more]
dlx6a1.907e-3575.00distal-less homeobox 6a [Source:NCBI gene;Acc:3058... [more]
dlx4a9.616e-3557.39distal-less homeobox 4a [Source:NCBI gene;Acc:3056... [more]
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BLAST of distal-less vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
shpk7.458e-3676.19sedoheptulokinase [Source:Xenbase;Acc:XB-GENE-9913... [more]
dlx13.481e-3569.15distal-less homeobox 1 [Source:NCBI gene;Acc:10010... [more]
ENSXETT00000050197.15.043e-3474.07distal-less homeobox 4 [Source:NCBI gene;Acc:10049... [more]
dlx11.562e-3369.15distal-less homeobox 1 [Source:NCBI gene;Acc:10010... [more]
dlx27.911e-3371.76distal-less homeobox 2 [Source:NCBI gene;Acc:49342... [more]
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BLAST of distal-less vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dlx15.427e-3651.30distal-less homeobox 1 [Source:MGI Symbol;Acc:MGI:... [more]
Dlx69.246e-3675.00distal-less homeobox 6 [Source:MGI Symbol;Acc:MGI:... [more]
Dlx62.360e-3575.00distal-less homeobox 6 [Source:MGI Symbol;Acc:MGI:... [more]
Dlx62.360e-3575.00distal-less homeobox 6 [Source:MGI Symbol;Acc:MGI:... [more]
Dlx23.255e-3371.76distal-less homeobox 2 [Source:MGI Symbol;Acc:MGI:... [more]
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BLAST of distal-less vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P53773|DLL1_XENLA8.127e-3673.86Homeobox protein DLL-1 OS=Xenopus laevis OX=8355 G... [more]
sp|Q98875|DLX1A_DANRE1.660e-3568.37Homeobox protein Dlx1a OS=Danio rerio OX=7955 GN=d... [more]
sp|P56177|DLX1_HUMAN3.509e-3551.30Homeobox protein DLX-1 OS=Homo sapiens OX=9606 GN=... [more]
sp|Q64317|DLX1_MOUSE3.796e-3551.30Homeobox protein DLX-1 OS=Mus musculus OX=10090 GN... [more]
sp|P20009|DLL_DROME3.811e-3569.00Homeotic protein distal-less OS=Drosophila melanog... [more]
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BLAST of distal-less vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
H9B8J60.000e+0100.00Distal-less OS=Schmidtea mediterranea OX=79327 PE=... [more]
T1D1545.711e-9171.15Dlx (Fragment) OS=Dendrocoelum lacteum OX=27895 PE... [more]
A0A2Z5VI941.251e-3657.33Homeobox protein Dlx (Fragment) OS=Nipponacmea fus... [more]
E1UGZ42.522e-3650.28Distal-less protein OS=Euperipatoides kanangrensis... [more]
A0A1S3I8F24.734e-3675.56homeobox protein Dlx1a isoform X2 OS=Lingula ungui... [more]
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BLAST of distal-less vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dlx1a3.771e-3756.30distal-less homeobox 1 [Source:NCBI gene;Acc:10303... [more]
dlx6a4.561e-3675.00distal-less homeobox 6 [Source:NCBI gene;Acc:10302... [more]
dlx21.574e-3370.45distal-less homeobox 2 [Source:NCBI gene;Acc:10303... [more]
ENSAMXT00000042049.11.623e-3371.60homeobox protein Dlx4a-like [Source:NCBI gene;Acc:... [more]
dlx2b2.006e-3368.54Astyanax mexicanus homeobox protein Dlx2b-like (LO... [more]
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BLAST of distal-less vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dlx5a9.311e-3175.64distal-less homeobox 5a [Source:NCBI gene;Acc:3056... [more]
dlx6a7.347e-2471.88distal-less homeobox 6a [Source:NCBI gene;Acc:3058... [more]
ENSPMAT00000001141.17.873e-1759.32pep scaffold:Pmarinus_7.0:GL478075:36995:38394:-1 ... [more]
barhl21.998e-1656.45BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
MSX12.008e-1658.73msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391][more]
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BLAST of distal-less vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
PHO25.504e-636.84Homeobox transcription factor; regulatory targets ... [more]
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BLAST of distal-less vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO465554.569e-3178.26Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
MSX1.744e-1758.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO422433.484e-1760.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO324952.440e-1652.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO350732.741e-1650.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of distal-less vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dlx1a2.820e-3666.33distal-less homeobox 1 [Source:NCBI gene;Acc:10116... [more]
dlx6a6.236e-3675.00distal-less homeobox 6 [Source:NCBI gene;Acc:10115... [more]
dlx23.247e-3470.00distal-less homeobox 2 [Source:NCBI gene;Acc:10004... [more]
dlx4b3.780e-3275.32homeobox protein Dlx4b [Source:NCBI gene;Acc:10115... [more]
dlx3b6.845e-3268.48distal-less homeobox 3 [Source:NCBI gene;Acc:10115... [more]
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BLAST of distal-less vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000045025.10.000e+0100.00SMESG000045025.1[more]
SMESG000045025.10.000e+0100.00SMESG000045025.1[more]
SMESG000019757.13.290e-1863.49SMESG000019757.1[more]
SMESG000019757.13.526e-1863.49SMESG000019757.1[more]
SMESG000021901.11.261e-1744.68SMESG000021901.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30003366
GenBankAFC87781.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003366 ID=SMED30003366|Name=distal-less|organism=Schmidtea mediterranea sexual|type=transcript|length=1974bp
CTGCTTCTTCCAACAAGTCATAATTAGGGCTCATTTTTACAGCGTTGTGT
TGACAACAATTAAATTACAGAACAGTTGTTCCTCGAATTAATTTGAGCAA
TTTTCCCTCTGATTACAGGTGTCCAGTGACTTCAGCTATAATCATCGTAT
TACAACGTAGTCTCAACCACCTCCACGCCAGTCGTAATTGCATAATCATT
GAAGATGATCTCCACTATGCCTCATTGTAATTTACAAGCTTCAAATGATC
TGTTTGAACCTCCCACTGCATCCACAGGATCAGAAACCCAATCCCACTCT
TTGCAATATCCCATCACATCGTCAGGATCATATGAATTTATGGACAATGG
GTTATTTTCATCCGCCTTACCAGATTCTCCATCTAAATCTGATATCAAAC
CACCTCAAGGTCTACTTCCACCGTTTGGGTTATCAAAACTAGATCCTCAG
TCATTTTATGGGTTTCCAAATCAATATGATATGCTTTATCCAAATATGTC
CACTAGACTTTATGCAGCGTCAGATAATTGCAACGAACCGAATTTATCGC
TCACAAAAACTTCCATTTTTAGTAATTCATCAAATCTTGCATATTCATCG
CTTGGATGCGACAATTTGCCAGTGTCGTCACCAACTGATATTTTGCAAGA
TGGTTTTGGCGGTATCAATTCGCACAAAAAAGATCTCCATTCGATTTCTG
GATTAGGAATATCAACTTCAAACAATCAACAACTAATGCCTCCATTGTCA
ACTCCGGGATATCGAAATATCAATCAACAATTAAATCCCGGAACGAACAG
TTCGGTTATTTTAGCTCGCAACTTTAACTCCCCTTATGGAACACAACAAT
CAACGTCAGCTTTGGGTCACTTACATCAGAATTATCCAACGAATTCTCAT
AACTATATGTCCAGTCAATCTATGGCAGCGGCAGTTTATAACTATCAGCA
CAACATGGTATTCCCCACTGGGCAAATGACCCCTCCATCTATGAAAGAAG
ATATTCAAAGAGAAGATCAAATTAGAGTTTCGGGTAAAGGAAAGAAAATT
CGAAAGCCTCGAACTATTTATTCAAGTCTGCAGCTACAACAATTGAGTAA
AAGATTCCAACGAACTCAATACCTCAGTTTACCAGAACGAGCTGAACTCG
CCAGTTCTTTAGGTTTAACACAGACTCAGGTAAAAATCTGGTTTCAAAAT
CGTCGGTCCAAGTATAAAAAGCTTATTAAGCAAGGTCAGGATCCAAGCAT
CCTGATGAATGGAGAATTTAATGACAGCATGGATGAAATGACGGAAGATC
AAATCGACGAAGATAATTGTATCAAACCAAAAGCAGAAATGCTATTAACA
AGCGATCCAAATAATCCTAGAGGCGATAGTTCTGATATTCCAACTGAAAC
TTCAGAAGCCTCAAGTCCCGTTTTGAAGCAACAACAAACTGTAACTTCCA
TTCCATCGAGTGGATCTCCAAATAATAAATATTCTCTCGATGGAGGATTG
GTTTCTCATTATCACGGTGCAATAGATCCATATCCCTCACAATTAACAAA
TCCTCATCAACTTAGTTATTATACAAATAACATGAACAATTCCCAACTGC
CACTTGGAACCAGTGGGTTCATTGACTCCAGTTATTTGGGAATGGGTCAA
TCCATGAATCACTTAACGGCCCAGTCGGGCTATCAGTACTATTTGAACCC
CTACAACACGAATTCCTACCCGACCTGGTACTCTTCAGAATGTTTACTCA
ACAACGTCGATTTTAAATAACTCTATCTAACCATCTCAGACTGTAATTCA
CCTGTAATAATAATATTGTAGTTTTAGTAGTGGTTTTTATTTTAATATAA
ATACATATTCGAATGGATATAAAATTGATAGCCGTTTCTCGCTCCATTGA
ATCCTAGTCTTCAAAAGTCGTCGGACTCGGCCACCGTTGCCCGAACAGTC
GAATTTAAAGCCCTTAATTTCCGG
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protein sequence of SMED30003366-orf-1

>SMED30003366-orf-1 ID=SMED30003366-orf-1|Name=SMED30003366-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=522bp
MISTMPHCNLQASNDLFEPPTASTGSETQSHSLQYPITSSGSYEFMDNGL
FSSALPDSPSKSDIKPPQGLLPPFGLSKLDPQSFYGFPNQYDMLYPNMST
RLYAASDNCNEPNLSLTKTSIFSNSSNLAYSSLGCDNLPVSSPTDILQDG
FGGINSHKKDLHSISGLGISTSNNQQLMPPLSTPGYRNINQQLNPGTNSS
VILARNFNSPYGTQQSTSALGHLHQNYPTNSHNYMSSQSMAAAVYNYQHN
MVFPTGQMTPPSMKEDIQREDQIRVSGKGKKIRKPRTIYSSLQLQQLSKR
FQRTQYLSLPERAELASSLGLTQTQVKIWFQNRRSKYKKLIKQGQDPSIL
MNGEFNDSMDEMTEDQIDEDNCIKPKAEMLLTSDPNNPRGDSSDIPTETS
EASSPVLKQQQTVTSIPSSGSPNNKYSLDGGLVSHYHGAIDPYPSQLTNP
HQLSYYTNNMNNSQLPLGTSGFIDSSYLGMGQSMNHLTAQSGYQYYLNPY
NTNSYPTWYSSECLLNNVDFK*
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Aliases
The feature 'distal-less' has the following synonyms
Synonym
dlx
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000036eye
PLANA:0000044cephalic ganglia
PLANA:0000099neuron
PLANA:0000140anterior region of the whole animal
PLANA:0000141dorsal region of the whole animal
PLANA:0000418head
PLANA:0002111X2 cell
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
Vocabulary: INTERPRO
TermDefinition
IPR020479Homeobox_metazoa
IPR000047HTH_motif
IPR001356Homeobox_dom
IPR009057Homeobox-like_sf
IPR017970Homeobox_CS
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0043565sequence-specific DNA binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000047Helix-turn-helix motifPRINTSPR00031HTHREPRESSRcoord: 311..320
score: 58.93
coord: 320..336
score: 69.56
IPR020479Homeobox domain, metazoaPRINTSPR00024HOMEOBOXcoord: 329..338
score: 76.79
coord: 304..315
score: 44.27
coord: 319..329
score: 63.87
IPR001356Homeobox domainSMARTSM00389HOX_1coord: 282..344
e-value: 3.5E-24
score: 96.3
IPR001356Homeobox domainPFAMPF00046Homeodomaincoord: 283..339
e-value: 1.4E-20
score: 72.8
IPR001356Homeobox domainPROSITEPS50071HOMEOBOX_2coord: 280..340
score: 20.39
IPR001356Homeobox domainCDDcd00086homeodomaincoord: 283..339
e-value: 1.72052E-23
score: 91.536
NoneNo IPR availableGENE3DG3DSA:1.10.10.60coord: 268..350
e-value: 2.0E-24
score: 86.9
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 385..423
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 380..423
NoneNo IPR availablePANTHERPTHR24327:SF74HOMEOTIC PROTEIN DISTAL-LESS-RELATEDcoord: 214..429
NoneNo IPR availablePANTHERPTHR24327FAMILY NOT NAMEDcoord: 214..429
IPR017970Homeobox, conserved sitePROSITEPS00027HOMEOBOX_1coord: 315..338
IPR009057Homeobox-like domain superfamilySUPERFAMILYSSF46689Homeodomain-likecoord: 279..346