BTB domain-containing protein

Overview
NameBTB domain-containing protein
Smed IDSMED30003345
Length (bp)970
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of BTB domain-containing protein (SMED30003345) t-SNE clustered cells

Violin plots show distribution of expression levels for BTB domain-containing protein (SMED30003345) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of BTB domain-containing protein (SMED30003345) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for BTB domain-containing protein (SMED30003345) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30003345

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30003345SMESG000014239.1 SmedASXL_001497SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30003345SMESG000014239.1 dd_Smed_v4_12440_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30003345SMESG000014239.1 dd_Smed_v4_12440_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30003345SMESG000014239.1 dd_Smed_v6_12440_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30003345SMESG000014239.1 OX_Smed_1.0.15931ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Human
Match: KCTD16 (potassium channel tetramerization domain containing 16 [Source:HGNC Symbol;Acc:HGNC:29244])

HSP 1 Score: 156.377 bits (394), Expect = 1.354e-43
Identity = 98/259 (37.84%), Postives = 146/259 (56.37%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLD--KSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI--DE--KSPS--------------------------------VITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            +V LNVGG  Y T  +TL+   +S+  ++    + + +D    +K + FIDRDG LFR++L++LR  +V LP +F E   LKREA Y++L +++  +  DE  +SP                                  ITVGYRG+   GR+G AD KFR++ RILV G+++  +EVF +TLN+SRDPD    +RY+SR++LK   LE+AF+ML + G+ MVA C S   +S       Q +++  W  Y E+VF R
Sbjct:   26 VVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRA-PERYTSRFYLKFKHLERAFDMLSECGFHMVA-CNSSVTASFI----NQYTDDKIWSSYTEYVFYR 278
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Human
Match: KCTD16 (potassium channel tetramerization domain containing 16 [Source:HGNC Symbol;Acc:HGNC:29244])

HSP 1 Score: 156.377 bits (394), Expect = 1.354e-43
Identity = 98/259 (37.84%), Postives = 146/259 (56.37%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLD--KSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI--DE--KSPS--------------------------------VITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            +V LNVGG  Y T  +TL+   +S+  ++    + + +D    +K + FIDRDG LFR++L++LR  +V LP +F E   LKREA Y++L +++  +  DE  +SP                                  ITVGYRG+   GR+G AD KFR++ RILV G+++  +EVF +TLN+SRDPD    +RY+SR++LK   LE+AF+ML + G+ MVA C S   +S       Q +++  W  Y E+VF R
Sbjct:   26 VVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRA-PERYTSRFYLKFKHLERAFDMLSECGFHMVA-CNSSVTASFI----NQYTDDKIWSSYTEYVFYR 278
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Human
Match: KCTD8 (potassium channel tetramerization domain containing 8 [Source:HGNC Symbol;Acc:HGNC:22394])

HSP 1 Score: 147.132 bits (370), Expect = 8.537e-40
Identity = 100/298 (33.56%), Postives = 143/298 (47.99%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKK-----------IFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYY-----------KLTEMMNQIDE--------------------------------------------KSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSRLN*PTYLPNNVH 779
            +V LNVGG  Y+T  +TLL   +S    +   SS   P  GA++            FIDRDG LFR+VL++LR  ++ LP +F E + L REA Y+           K+T+  +  DE                                            K    +T+GYRG++   RD  AD KFR+++RI+V G++   +EVF DTLN+SRDPD    ++Y+SR++LK   LEQAF+ L +AG+ MVA      NSSG+     Q  ++  W  Y E++F R       P   H
Sbjct:   45 VVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSS---PRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALLLRGAAAAVPSGPGAHGGGGGGGAQDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRQ-PEKYTSRFYLKFTYLEQAFDRLSEAGFHMVA-----CNSSGTAAFVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEH 333
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Human
Match: KCTD12 (potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678])

HSP 1 Score: 122.094 bits (305), Expect = 1.211e-31
Identity = 60/119 (50.42%), Postives = 80/119 (67.23%), Query Frame = 3 
Query:  387 ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            IT+GYRG++  GRD  AD KFR+++RI V GK +  +EVF DTLN+SRDPD    +RY+SRY+LK N LEQAF+ L ++G+ MVA   +GT +  S       SE+  W  Y E+VF R
Sbjct:  210 ITIGYRGSYTIGRDAQADAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDRP-PERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTGTCAFASST---DQSEDKIWTSYTEYVFCR 324

HSP 2 Score: 67.0106 bits (162), Expect = 6.924e-12
Identity = 34/95 (35.79%), Postives = 59/95 (62.11%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI 365
            IV LNVGG  Y+T + T++   +S+   +  +    +    +K + F+DRDG LFR++L++LR  ++ LP  F E   L+REA Y++L E++ ++
Sbjct:   35 IVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Human
Match: KCTD15 (potassium channel tetramerization domain containing 15 [Source:HGNC Symbol;Acc:HGNC:23297])

HSP 1 Score: 84.3445 bits (207), Expect = 4.469e-18
Identity = 64/228 (28.07%), Postives = 107/228 (46.93%), Query Frame = 3 
Query:   33 ISAHIFVVDDKTLKMDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQID---------EKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDT-------LNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSS 668
            ++A    +  +  K ++ VH++VGG  Y +   TL K  +S    L + +     ++  +  FIDRDG +FR+VL FLR  ++ LP +F +  LL  EA YY+L  M+ +++          +S +   +  R T   G             RI +SG+     EVF +T       +N   + D     R+    + + N + Q  E L+  G+++ ASCG G +SS
Sbjct:   40 LAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLG------------ERIALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIRFPLNGYCRLNSV-QVLERLFQRGFSVAASCGGGVDSS 254
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Celegans
Match: VM106R.1 (pep chromosome:WBcel235:II:10827716:10829556:-1 gene:WBGene00014848.1 transcript:VM106R.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:VM106R.1)

HSP 1 Score: 191.43 bits (485), Expect = 8.542e-59
Identity = 111/285 (38.95%), Postives = 154/285 (54.04%), Query Frame = 3 
Query:   36 SAHIFVVDDKTLKMDSI---VHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGA-----KKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKL---TEMMNQIDEKSP------------------SVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNG-FGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKP-------------------GQDSEENKWQHYNEFVFSR 743
            S +I+++ ++   M S+   + LNVGGT Y T ++TL K T+++   +   S   D            +F+DRDG LF +VL FLR  ++ LP  F E+  LK EA +Y+L   + +++     SP                    IT+GYRGTFAFGRDG ADVKFRKL RILV G+   CREVF DTLN+SRDP     G+RY+SR +LKH  LE+A +++ + G+ +VA+C SG N   +   P                     D EE +W HY E+VF R
Sbjct:   10 SIYIYILPNRAYYMTSVEDVITLNVGGTMYTTTRSTLSKETDTLLANIASGSLSEDEQANVVTLPDGTLFVDRDGPLFAYVLHFLRTDKLSLPEQFREVARLKDEADFYRLERFSTLLSNASSISPRPRTANGYNTITSGAETGGYITLGYRGTFAFGRDGQADVKFRKLHRILVCGRATLCREVFADTLNESRDPGGPDDGERYTSRLYLKHQCLERACDLMAEKGFKLVATCCSGANGLAAANHPILTSNMGNINQTELMNHRNCGDYEEQRWAHYTEYVFFR 294
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Celegans
Match: F32B4.5 (pep chromosome:WBcel235:I:11517769:11520660:-1 gene:WBGene00009315.1 transcript:F32B4.5a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F32B4.5)

HSP 1 Score: 75.485 bits (184), Expect = 3.408e-15
Identity = 42/99 (42.42%), Postives = 63/99 (63.64%), Query Frame = 3 
Query:  462 RILVSGKVNACREVFKDTLNDSRDPDNGFG-----DRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            RI+VSGKV  CR VF D+LN+ RD   G G     DRY+SR+FLKH+ LE+AF+ L  +GY ++ S       + SE+      +++++ H+++FVF R
Sbjct:  240 RIVVSGKVIMCRAVFGDSLNECRD---GGGTDFEMDRYTSRFFLKHSNLEKAFDQLASSGYRLIHS----NTFAPSEMPKHAAKDDSQFIHHSQFVFHR 331
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Celegans
Match: B0281.6 (pep chromosome:WBcel235:II:2301308:2302229:-1 gene:WBGene00015113.1 transcript:B0281.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:B0281.6)

HSP 1 Score: 67.3958 bits (163), Expect = 5.878e-13
Identity = 42/103 (40.78%), Postives = 56/103 (54.37%), Query Frame = 3 
Query:   78 DSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQIDEKSPSV 386
            +SIV LNVGGT ++TLK+TL K  + IF  L+       P       FIDR    F  VL ++R G V+LP +  EL+ LKREA YY L ++        P +
Sbjct:    5 ESIVKLNVGGTVFVTLKSTLTK-HHGIFKALVKTEM---PAEDGDSFFIDRSPKHFETVLNYIRSGDVDLPDSENELKELKREAEYYSLEKLATLCQSSMPKI 103
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Celegans
Match: ZC239.3 (pep chromosome:WBcel235:II:3216081:3216600:1 gene:WBGene00022566.1 transcript:ZC239.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZC239.3)

HSP 1 Score: 64.3142 bits (155), Expect = 1.649e-12
Identity = 41/113 (36.28%), Postives = 65/113 (57.52%), Query Frame = 3 
Query:   66 TLKMDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDK--SSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQIDEKSPSVITVG 398
            +L  D ++ LN+GG  + T K+TL+K  +  F + L    SS  DP      IF+DR  + F  VL F+R GR +LP    +L++L  EA YY+LTE+ +   ++  S++ +G
Sbjct:    2 SLFFDKVIRLNIGGKRFDTHKSTLMK-FDGYFKKFLQTPGSSLVDP------IFVDRSPTYFDIVLNFMRKGRADLPETLIDLKMLLDEAEYYELTELCDDC-KREISILDIG 106
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Celegans
Match: F22E5.12 (pep chromosome:WBcel235:II:2646328:2646843:-1 gene:WBGene00017710.1 transcript:F22E5.12.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F22E5.12)

HSP 1 Score: 63.929 bits (154), Expect = 2.132e-12
Identity = 39/100 (39.00%), Postives = 58/100 (58.00%), Query Frame = 3 
Query:   66 TLKMDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDK--SSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMN 359
            +L  D ++ LN+GG  + T K+TL+K  +  F + L    SS  DP      IF+DR  + F  VL F+R GR +LP    +L++L  EA YY+LTE+ +
Sbjct:    2 SLFFDKVIRLNIGGKRFDTHKSTLMKF-DGYFKKFLQTPGSSLVDP------IFVDRSPTYFDIVLNFMRKGRADLPETLKDLKMLLGEAEYYELTELCD 94
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Fly
Match: Ktl (gene:FBgn0038839 transcript:FBtr0347575)

HSP 1 Score: 257.684 bits (657), Expect = 1.364e-85
Identity = 127/227 (55.95%), Postives = 158/227 (69.60%), Query Frame = 3 
Query:   75 MDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI----DEKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            M  I+ LNVGG +Y T   TLL+  +++  EL  +   S       + F+DRDG LFR++L+FLR   + LP  F E Q L REA ++KLT M+  I    D + P  IT+GYRG+F FG+DGLADVKFRKLSRILV G+V  CREVF DTLN+SRDPD+G  DRY+SR+FLKH  +EQAF+ L+D GY M  SCGSGT  S +E KPG D+EEN+W HYNEFVF R
Sbjct:    1 MPEIIELNVGGVSYTTTLATLLQDKSTLLAELFGEGRDSLAKDSKGRYFLDRDGVLFRYILDFLRDKALHLPEGFRERQRLLREAEHFKLTAMLECIRSERDARPPGCITIGYRGSFQFGKDGLADVKFRKLSRILVCGRVAQCREVFGDTLNESRDPDHGGTDRYTSRFFLKHCYIEQAFDNLHDHGYRMAGSCGSGTAGSAAEPKPGVDTEENRWNHYNEFVFIR 227
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Fly
Match: Ktl (gene:FBgn0038839 transcript:FBtr0083986)

HSP 1 Score: 257.684 bits (657), Expect = 1.364e-85
Identity = 127/227 (55.95%), Postives = 158/227 (69.60%), Query Frame = 3 
Query:   75 MDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI----DEKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            M  I+ LNVGG +Y T   TLL+  +++  EL  +   S       + F+DRDG LFR++L+FLR   + LP  F E Q L REA ++KLT M+  I    D + P  IT+GYRG+F FG+DGLADVKFRKLSRILV G+V  CREVF DTLN+SRDPD+G  DRY+SR+FLKH  +EQAF+ L+D GY M  SCGSGT  S +E KPG D+EEN+W HYNEFVF R
Sbjct:    1 MPEIIELNVGGVSYTTTLATLLQDKSTLLAELFGEGRDSLAKDSKGRYFLDRDGVLFRYILDFLRDKALHLPEGFRERQRLLREAEHFKLTAMLECIRSERDARPPGCITIGYRGSFQFGKDGLADVKFRKLSRILVCGRVAQCREVFGDTLNESRDPDHGGTDRYTSRFFLKHCYIEQAFDNLHDHGYRMAGSCGSGTAGSAAEPKPGVDTEENRWNHYNEFVFIR 227
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Fly
Match: twz (gene:FBgn0034636 transcript:FBtr0071692)

HSP 1 Score: 63.5438 bits (153), Expect = 4.360e-11
Identity = 34/94 (36.17%), Postives = 55/94 (58.51%), Query Frame = 3 
Query:   87 VHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQID 368
            VH++VGGT Y +   TL K   S   +L +       ++  +  FIDRDG +FR +L F+R  R+ +  +F +L+LL  EA YY++  M+ Q++
Sbjct:  108 VHIDVGGTIYTSSLETLTKYPESKLAKLFNGQIPIVLDSLKQHYFIDRDGGMFRHILNFMRNSRLLIAEDFPDLELLLEEARYYEVEPMIKQLE 201
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Fly
Match: twz (gene:FBgn0034636 transcript:FBtr0308642)

HSP 1 Score: 63.5438 bits (153), Expect = 5.804e-11
Identity = 34/94 (36.17%), Postives = 55/94 (58.51%), Query Frame = 3 
Query:   87 VHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQID 368
            VH++VGGT Y +   TL K   S   +L +       ++  +  FIDRDG +FR +L F+R  R+ +  +F +L+LL  EA YY++  M+ Q++
Sbjct:  137 VHIDVGGTIYTSSLETLTKYPESKLAKLFNGQIPIVLDSLKQHYFIDRDGGMFRHILNFMRNSRLLIAEDFPDLELLLEEARYYEVEPMIKQLE 230
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Fly
Match: CG9467 (gene:FBgn0037758 transcript:FBtr0082156)

HSP 1 Score: 53.5286 bits (127), Expect = 1.634e-7
Identity = 33/96 (34.38%), Postives = 54/96 (56.25%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDK--SSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI 365
            +V+LNVGG  + T + TL    ++ F  LL    SS  D +     IFIDRD +LF  +L +LR   +++ +   E++ L+ EA YY +T +  ++
Sbjct:   12 LVNLNVGGQRFSTSRQTLTWIPDTFFTALLSGRISSLRDEHNA---IFIDRDPTLFSIILNYLRTKDIDIKN--CEIRALRHEAEYYGITPLTKRL 102
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Zebrafish
Match: kctd12.2 (potassium channel tetramerisation domain containing 12.2 [Source:ZFIN;Acc:ZDB-GENE-060117-4])

HSP 1 Score: 165.622 bits (418), Expect = 5.073e-49
Identity = 101/271 (37.27%), Postives = 147/271 (54.24%), Query Frame = 3 
Query:   54 VDDKTLKMDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMM----------NQIDE----------------------KSPSV-------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENK-WQHYNEFVFSR 743
             D  + +   I+ LNVGG  Y+T  +TLL   NS+   +  +   ++  T +K + F+DRDG LFR++L++LR   + LP  F E   L +EA Y++L ++           N I E                      +SPS+       IT+GYRG++  GRD   D KFR+++RI V GK +  +EVF +TLN+SRDPD    +RY+SRY+LK+N LEQAF+ L + G+ MVA   +GT +  S      D  E+K W  Y E+VF R
Sbjct:    6 ADASSPRFSEIIELNVGGQVYVTRHSTLLSVPNSLLWTMFSQKKPAELTTDSKGRFFLDRDGFLFRYILDYLRDQTLVLPDYFKEKASLLKEAEYFQLQDLAKRLKPAVSKENSISEEVCQSDPEEAALAGTSMTCTGPRSPSLDARKTGFITIGYRGSYTIGRDLQQDAKFRRVARITVCGKTSLAKEVFGETLNESRDPDRP-PERYTSRYYLKYNFLEQAFDRLAEVGFHMVACSSTGTCAYAS-----NDPNEDKIWTSYTEYVFCR 270
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Zebrafish
Match: kctd12.2 (potassium channel tetramerisation domain containing 12.2 [Source:ZFIN;Acc:ZDB-GENE-060117-4])

HSP 1 Score: 165.622 bits (418), Expect = 5.073e-49
Identity = 101/271 (37.27%), Postives = 147/271 (54.24%), Query Frame = 3 
Query:   54 VDDKTLKMDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMM----------NQIDE----------------------KSPSV-------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENK-WQHYNEFVFSR 743
             D  + +   I+ LNVGG  Y+T  +TLL   NS+   +  +   ++  T +K + F+DRDG LFR++L++LR   + LP  F E   L +EA Y++L ++           N I E                      +SPS+       IT+GYRG++  GRD   D KFR+++RI V GK +  +EVF +TLN+SRDPD    +RY+SRY+LK+N LEQAF+ L + G+ MVA   +GT +  S      D  E+K W  Y E+VF R
Sbjct:    6 ADASSPRFSEIIELNVGGQVYVTRHSTLLSVPNSLLWTMFSQKKPAELTTDSKGRFFLDRDGFLFRYILDYLRDQTLVLPDYFKEKASLLKEAEYFQLQDLAKRLKPAVSKENSISEEVCQSDPEEAALAGTSMTCTGPRSPSLDARKTGFITIGYRGSYTIGRDLQQDAKFRRVARITVCGKTSLAKEVFGETLNESRDPDRP-PERYTSRYYLKYNFLEQAFDRLAEVGFHMVACSSTGTCAYAS-----NDPNEDKIWTSYTEYVFCR 270
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Zebrafish
Match: kctd12.1 (potassium channel tetramerisation domain containing 12.1 [Source:ZFIN;Acc:ZDB-GENE-030902-5])

HSP 1 Score: 160.614 bits (405), Expect = 8.728e-47
Identity = 100/271 (36.90%), Postives = 143/271 (52.77%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKL-----------------TEMMNQIDEKSPSV--------------------------------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENK-WQHYNEFVFSR 743
            I+ LNVGG  Y+T  TTL+   +S+   +  K + ++    +K + F+DRDG LFR++L++LR   + LP  F E   L+REA +++L                 T+ + Q D + PS                                 ITVGYRG++  GRD   D KFR+++RI V GK +  +EVF DTLN+SRDPD    +RY+SRY+LK+N LEQAF+ L + G+ MVA   +GT +  S      D  E+K W  Y E+VF R
Sbjct:   23 IIELNVGGQVYVTRHTTLIAVPDSLLWNMFSKKTPAELARDSKGRFFLDRDGFLFRYILDYLRDLNLVLPDYFPEKSRLQREAEFFQLRDLSKLLSPKMSKDNSITDEICQSDSEEPSASATPVVGPETSRTLSVASSAHSPSLESRKSGYITVGYRGSYTMGRDIQTDAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDRP-PERYTSRYYLKYNFLEQAFDKLSEFGFQMVACSSTGTCAYSS-----SDPNEDKVWTSYTEYVFCR 287
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Zebrafish
Match: kctd12.1 (potassium channel tetramerisation domain containing 12.1 [Source:ZFIN;Acc:ZDB-GENE-030902-5])

HSP 1 Score: 160.614 bits (405), Expect = 8.728e-47
Identity = 100/271 (36.90%), Postives = 143/271 (52.77%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKL-----------------TEMMNQIDEKSPSV--------------------------------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENK-WQHYNEFVFSR 743
            I+ LNVGG  Y+T  TTL+   +S+   +  K + ++    +K + F+DRDG LFR++L++LR   + LP  F E   L+REA +++L                 T+ + Q D + PS                                 ITVGYRG++  GRD   D KFR+++RI V GK +  +EVF DTLN+SRDPD    +RY+SRY+LK+N LEQAF+ L + G+ MVA   +GT +  S      D  E+K W  Y E+VF R
Sbjct:   23 IIELNVGGQVYVTRHTTLIAVPDSLLWNMFSKKTPAELARDSKGRFFLDRDGFLFRYILDYLRDLNLVLPDYFPEKSRLQREAEFFQLRDLSKLLSPKMSKDNSITDEICQSDSEEPSASATPVVGPETSRTLSVASSAHSPSLESRKSGYITVGYRGSYTMGRDIQTDAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDRP-PERYTSRYYLKYNFLEQAFDKLSEFGFQMVACSSTGTCAYSS-----SDPNEDKVWTSYTEYVFCR 287
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Zebrafish
Match: kctd12b (potassium channel tetramerisation domain containing 12b [Source:ZFIN;Acc:ZDB-GENE-050417-104])

HSP 1 Score: 157.532 bits (397), Expect = 1.042e-45
Identity = 97/272 (35.66%), Postives = 140/272 (51.47%), Query Frame = 3 
Query:   69 LKMDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI-------------------DEKSPSV---------------------------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            L    I+ LNVGG  Y+T   TL    +S+  ++  + S  D     K + FIDRDG LFR++L+++R  ++ LP +F E   L+REA ++ L E++  +                   DE SP                             IT+G RG++  GRD   D KFR+++RI+V GK +  +EVF +TLN+S DPD    DRY+SRY+LK   LEQAF+ L DAG+ MVA      NS+G+       +++  W  YNE+VF R
Sbjct:   15 LAFPEIIELNVGGQVYITRYLTLTSVPDSLLWKMFSQKSSKDLARDTKGRFFIDRDGFLFRYILDYMRDQQLVLPEHFPEQGRLQREAEFFNLPELVQLLAPKISKQNTLGDDGCQTDQDESSPGANITCNLSSLGAYSSLGAATADSQRSGFITIGCRGSYTLGRDCQTDAKFRRVARIMVCGKTSLAKEVFGETLNESHDPDRQ-PDRYTSRYYLKFTSLEQAFDRLADAGFHMVA-----CNSTGTCAFAHVQTDDKIWTSYNEYVFYR 280
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Xenopus
Match: zmat3 (zinc finger matrin-type 3 [Source:Xenbase;Acc:XB-GENE-1014344])

HSP 1 Score: 161.77 bits (408), Expect = 6.877e-47
Identity = 99/271 (36.53%), Postives = 145/271 (53.51%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMM----------NQI---------DEKSPSV-------------------------------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            I+ LNVGG  Y+T   TL+    S+  E+  + +       +K + F+DRDG LFR+VL+++R  ++ LP +F E   L+REA +++L E++          N I         +E+SP+V                               IT+GYRG++  GRD   D KFR+++RI+V GK +  +EVF DTLNDSRDPD    +RY+SRY+LK   LEQAF+ L DAG+ MVA      NS+G+       +++  W  Y E+VF R
Sbjct:   42 IIELNVGGQVYITRYPTLVSVPGSLLSEMFSQRNSRPLARDSKGRYFLDRDGFLFRYVLDYMRDQQLVLPDHFPERLRLQREAEFFRLPELVKILAPKVSKQNSIGDDAFQSDSEEQSPNVEVARNLASVSAALAAAAGNQSTMSDLRRSGFITIGYRGSYTLGRDSQTDAKFRRVARIMVCGKTSLAKEVFGDTLNDSRDPDRP-PERYTSRYYLKFTFLEQAFDRLADAGFHMVAC-----NSTGTCAFAHDQTDDKIWTSYTEYVFYR 306
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000022598.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV461789.1:4151:5778:-1 gene:ENSXETG00000010726.1 transcript:ENSXETT00000022598.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 158.303 bits (399), Expect = 8.614e-46
Identity = 92/251 (36.65%), Postives = 142/251 (56.57%), Query Frame = 3 
Query:   87 VHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSD-PNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMM-------------------NQIDEKSPS--------------VITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVF 737
            + LNVGG  Y+T  TTL    +S    + ++++  + P     + FIDRDG LFR++L+FLR  ++ LP +F E + L REA Y++L +++                   + I++ S S               IT+GYRG++   RD  AD KFR+++RI+V G++   +EVF DTLN+SRDPD    ++Y+SR++LK   LEQAF+ L +AG+ MVA C    NS+G+     Q  ++  W  Y E++F
Sbjct:   10 IKLNVGGQVYVTKHTTLTSVPDSTLYSMFNRNNVKEMPRDNRARFFIDRDGFLFRYILDFLRDKQLSLPDHFPEKERLLREAEYFQLGDLVKLLTPKVTKQSSLNDEGCQSDIEDSSQSSDLVRTAALDKKSGFITIGYRGSYTMVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRP-PEKYTSRFYLKFTYLEQAFDRLSEAGFHMVA-C----NSTGTAAFVNQYRDDKIWSSYTEYIF 254
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Xenopus
Match: lsm11 (LSM11, U7 small nuclear RNA associated [Source:Xenbase;Acc:XB-GENE-1007644])

HSP 1 Score: 155.221 bits (391), Expect = 3.140e-43
Identity = 98/259 (37.84%), Postives = 144/259 (55.60%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELL--DKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMN--------------------QIDEKS-----PSV-----------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            +V LNVGG  Y T   TL    +S+  ++    + S +D    AK + FIDRDG LFR+VL++LR  +V LP +F E   LKREA Y++L +++                     ++ + S     PS            +TVGYRG+   GR+  AD KFR++ RILV G+++  +EVF DTLN+SRDPD    ++Y+SR++LK   LE+AF+ML ++G+ MVA C S   +S       Q +++  W  Y E+VF R
Sbjct:   26 VVELNVGGQVYFTRHATLTSIPHSLLWKMFTCKRDSVNDLAKDAKGRFFIDRDGFLFRYVLDYLRDRQVVLPDHFPERGRLKREAEYFQLPDLVKLLIPEEVKQSPDDYCHSDYEEVSQGSETRICPSASLMPSDRKWGFVTVGYRGSCTMGRESQADAKFRRVPRILVCGRISLAKEVFGDTLNESRDPDRA-PEKYTSRFYLKFKHLERAFDMLSESGFLMVA-CNSSVTASFV----NQYTDDKIWSSYTEYVFYR 278
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000008990.1 (potassium channel tetramerization domain containing 8 [Source:NCBI gene;Acc:100492650])

HSP 1 Score: 149.443 bits (376), Expect = 2.173e-41
Identity = 84/228 (36.84%), Postives = 130/228 (57.02%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSD-PNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQID-------EKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            ++ LNVGG  Y+T  TTL    +S    + ++++  + P     + FIDRDG LFR++L+FLR  ++ L + +     L  E     + +     D       +K    IT+GYRG++   RD  AD KFR+++RI+V G++   +EVF DTLN+SRDPD    ++Y+SR++LK   LEQAF+ L +AG+ MVA      NS+G+     Q  ++  W  Y E++F R
Sbjct:   24 VIELNVGGQVYVTKHTTLTSVPDSTLYSMFNRNNVKEMPRDNRTRFFIDRDGFLFRYILDFLRDKQLSLEAEY--FHSLNDEGCQSDIEDSSQSSDLVRTAALDKKSGFITIGYRGSYTMVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRP-PEKYTSRFYLKFTYLEQAFDRLSEAGFHMVA-----CNSTGTAAFVNQYRDDKIWSSYTEYIFYR 243
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Xenopus
Match: kctd12 (potassium channel tetramerization domain containing 12 [Source:NCBI gene;Acc:100125072])

HSP 1 Score: 121.709 bits (304), Expect = 1.424e-31
Identity = 60/119 (50.42%), Postives = 80/119 (67.23%), Query Frame = 3 
Query:  387 ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            ITVGYRG++  GR+  AD KFR+++RI V GK +  +EVF +TLN+SRDPD    +RY+SRY+LK N LEQAF+ L +AG+ MVA   +GT +  S       SE+  W  Y E+VF R
Sbjct:  210 ITVGYRGSYTIGREAQADAKFRRVARITVCGKTSLAKEVFGETLNESRDPDRP-PERYTSRYYLKFNFLEQAFDKLSEAGFHMVACSSTGTCAFAS----NDQSEDKVWTSYTEYVFCR 323

HSP 2 Score: 67.781 bits (164), Expect = 2.715e-12
Identity = 36/96 (37.50%), Postives = 60/96 (62.50%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQID 368
            IV LNVGG  Y+T  TTL+   +S+   +  +    +    +K + F+DRDG LFR+VL++LR  ++ LP  F E   L+REA +++L E++ +++
Sbjct:   33 IVELNVGGQVYVTRHTTLVSVPDSLLWRMFSQQKPGELARDSKGRFFLDRDGFLFRYVLDYLRDLQLVLPDYFPERSRLQREAEHFQLPELVKRLN 128
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Mouse
Match: Kctd12b (potassium channel tetramerisation domain containing 12b [Source:MGI Symbol;Acc:MGI:2444667])

HSP 1 Score: 164.466 bits (415), Expect = 3.339e-48
Identity = 105/278 (37.77%), Postives = 145/278 (52.16%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELL---DKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEM-------MNQI------------DEKSPSV------------------------------------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            I+ LNVGG  Y+T   TL+    S   E+    +  S    N G  + FIDRDG LFR+VL+++R  +V LP +F E   L REA Y+KL E+       MN++            +E SPS+                                    IT+GYRG++  GRD  AD KFR+++RI+V GK++  +EVF DTLN+SRDPD    +RY+SRY+LK   LEQAF+ L DAG+ MVA      NS+G+       +++  W  Y E+VF R
Sbjct:   22 IIELNVGGQVYITRYPTLISIPGSRLWEMFSVKNPCSLIQDNKG--RFFIDRDGFLFRYVLDYMRDMQVVLPDHFPECGRLHREAEYFKLPELAKMLAPKMNKLNSIGNDSCPIDLEELSPSIDTTFNFSSTNSIHISGPDNPMVLRAAPGSELKKAGFITIGYRGSYTLGRDSQADAKFRRVARIMVCGKISLAKEVFGDTLNESRDPDRP-PERYTSRYYLKFTFLEQAFDKLADAGFHMVA-----CNSTGTCTVTHDQTDDRIWTSYTEYVFYR 291
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Mouse
Match: Kctd12b (potassium channel tetramerisation domain containing 12b [Source:MGI Symbol;Acc:MGI:2444667])

HSP 1 Score: 164.466 bits (415), Expect = 3.339e-48
Identity = 105/278 (37.77%), Postives = 145/278 (52.16%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELL---DKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEM-------MNQI------------DEKSPSV------------------------------------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            I+ LNVGG  Y+T   TL+    S   E+    +  S    N G  + FIDRDG LFR+VL+++R  +V LP +F E   L REA Y+KL E+       MN++            +E SPS+                                    IT+GYRG++  GRD  AD KFR+++RI+V GK++  +EVF DTLN+SRDPD    +RY+SRY+LK   LEQAF+ L DAG+ MVA      NS+G+       +++  W  Y E+VF R
Sbjct:   22 IIELNVGGQVYITRYPTLISIPGSRLWEMFSVKNPCSLIQDNKG--RFFIDRDGFLFRYVLDYMRDMQVVLPDHFPECGRLHREAEYFKLPELAKMLAPKMNKLNSIGNDSCPIDLEELSPSIDTTFNFSSTNSIHISGPDNPMVLRAAPGSELKKAGFITIGYRGSYTLGRDSQADAKFRRVARIMVCGKISLAKEVFGDTLNESRDPDRP-PERYTSRYYLKFTFLEQAFDKLADAGFHMVA-----CNSTGTCTVTHDQTDDRIWTSYTEYVFYR 291
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Mouse
Match: Kctd16 (potassium channel tetramerisation domain containing 16 [Source:MGI Symbol;Acc:MGI:1914659])

HSP 1 Score: 157.147 bits (396), Expect = 4.628e-44
Identity = 96/259 (37.07%), Postives = 145/259 (55.98%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLD--KSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQID----EKSPS--------------------------------VITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            ++ LNVGG  Y T  +TL+   +S+  ++    + + +D    +K + FIDRDG LFR++L++LR  +V LP +F E   LKREA Y++L +++  +     ++SP                                  ITVGYRG+   GR+G AD KFR++ RILV G+++  +EVF +TLN+SRDPD    +RY+SR++LK   LE+AF+ML + G+ MVA C S   +S       Q +E+  W  Y E+VF R
Sbjct:   26 VIELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPERGRLKREAEYFQLPDLVKLLAPEDVKQSPDEFCHSDFEDASQGSDTRICPPSSLLPHDRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRA-PERYTSRFYLKFKHLERAFDMLSECGFHMVA-CNSSVTASFV----NQYTEDKIWSSYTEYVFYR 278
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Mouse
Match: Kctd16 (potassium channel tetramerisation domain containing 16 [Source:MGI Symbol;Acc:MGI:1914659])

HSP 1 Score: 157.147 bits (396), Expect = 4.628e-44
Identity = 96/259 (37.07%), Postives = 145/259 (55.98%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLD--KSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQID----EKSPS--------------------------------VITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            ++ LNVGG  Y T  +TL+   +S+  ++    + + +D    +K + FIDRDG LFR++L++LR  +V LP +F E   LKREA Y++L +++  +     ++SP                                  ITVGYRG+   GR+G AD KFR++ RILV G+++  +EVF +TLN+SRDPD    +RY+SR++LK   LE+AF+ML + G+ MVA C S   +S       Q +E+  W  Y E+VF R
Sbjct:   26 VIELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPERGRLKREAEYFQLPDLVKLLAPEDVKQSPDEFCHSDFEDASQGSDTRICPPSSLLPHDRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRA-PERYTSRFYLKFKHLERAFDMLSECGFHMVA-CNSSVTASFV----NQYTEDKIWSSYTEYVFYR 278
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Mouse
Match: Kctd12 (potassium channel tetramerisation domain containing 12 [Source:MGI Symbol;Acc:MGI:2145823])

HSP 1 Score: 122.094 bits (305), Expect = 8.644e-32
Identity = 60/119 (50.42%), Postives = 80/119 (67.23%), Query Frame = 3 
Query:  387 ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            IT+GYRG++  GRD  AD KFR+++RI V GK +  +EVF DTLN+SRDPD    +RY+SRY+LK N LEQAF+ L ++G+ MVA   +GT +  S       SE+  W  Y E+VF R
Sbjct:  212 ITIGYRGSYTIGRDAQADAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDRP-PERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTGTCAFASST---DQSEDKIWTSYTEYVFCR 326

HSP 2 Score: 67.0106 bits (162), Expect = 4.903e-12
Identity = 34/95 (35.79%), Postives = 59/95 (62.11%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI 365
            IV LNVGG  Y+T + T++   +S+   +  +    +    +K + F+DRDG LFR++L++LR  ++ LP  F E   L+REA Y++L E++ ++
Sbjct:   35 IVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129
[Close]
BLAST of BTB domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5DTY9|KCD16_MOUSE (BTB/POZ domain-containing protein KCTD16 OS=Mus musculus OX=10090 GN=Kctd16 PE=1 SV=2)

HSP 1 Score: 157.147 bits (396), Expect = 3.238e-43
Identity = 96/259 (37.07%), Postives = 145/259 (55.98%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLD--KSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQID----EKSPS--------------------------------VITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            ++ LNVGG  Y T  +TL+   +S+  ++    + + +D    +K + FIDRDG LFR++L++LR  +V LP +F E   LKREA Y++L +++  +     ++SP                                  ITVGYRG+   GR+G AD KFR++ RILV G+++  +EVF +TLN+SRDPD    +RY+SR++LK   LE+AF+ML + G+ MVA C S   +S       Q +E+  W  Y E+VF R
Sbjct:   26 VIELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPERGRLKREAEYFQLPDLVKLLAPEDVKQSPDEFCHSDFEDASQGSDTRICPPSSLLPHDRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRA-PERYTSRFYLKFKHLERAFDMLSECGFHMVA-CNSSVTASFV----NQYTEDKIWSSYTEYVFYR 278
[Close]
BLAST of BTB domain-containing protein vs. UniProt/SwissProt
Match: sp|Q68DU8|KCD16_HUMAN (BTB/POZ domain-containing protein KCTD16 OS=Homo sapiens OX=9606 GN=KCTD16 PE=1 SV=1)

HSP 1 Score: 156.377 bits (394), Expect = 6.505e-43
Identity = 98/259 (37.84%), Postives = 146/259 (56.37%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLD--KSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI--DE--KSPS--------------------------------VITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            +V LNVGG  Y T  +TL+   +S+  ++    + + +D    +K + FIDRDG LFR++L++LR  +V LP +F E   LKREA Y++L +++  +  DE  +SP                                  ITVGYRG+   GR+G AD KFR++ RILV G+++  +EVF +TLN+SRDPD    +RY+SR++LK   LE+AF+ML + G+ MVA C S   +S       Q +++  W  Y E+VF R
Sbjct:   26 VVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRA-PERYTSRFYLKFKHLERAFDMLSECGFHMVA-CNSSVTASFI----NQYTDDKIWSSYTEYVFYR 278
[Close]
BLAST of BTB domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6ZWB6|KCTD8_HUMAN (BTB/POZ domain-containing protein KCTD8 OS=Homo sapiens OX=9606 GN=KCTD8 PE=1 SV=1)

HSP 1 Score: 147.132 bits (370), Expect = 4.100e-39
Identity = 100/298 (33.56%), Postives = 143/298 (47.99%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKK-----------IFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYY-----------KLTEMMNQIDE--------------------------------------------KSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSRLN*PTYLPNNVH 779
            +V LNVGG  Y+T  +TLL   +S    +   SS   P  GA++            FIDRDG LFR+VL++LR  ++ LP +F E + L REA Y+           K+T+  +  DE                                            K    +T+GYRG++   RD  AD KFR+++RI+V G++   +EVF DTLN+SRDPD    ++Y+SR++LK   LEQAF+ L +AG+ MVA      NSSG+     Q  ++  W  Y E++F R       P   H
Sbjct:   45 VVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSS---PRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALLLRGAAAAVPSGPGAHGGGGGGGAQDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRQ-PEKYTSRFYLKFTYLEQAFDRLSEAGFHMVA-----CNSSGTAAFVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEH 333
[Close]
BLAST of BTB domain-containing protein vs. UniProt/SwissProt
Match: sp|Q96CX2|KCD12_HUMAN (BTB/POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 5.817e-31
Identity = 60/119 (50.42%), Postives = 80/119 (67.23%), Query Frame = 3 
Query:  387 ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            IT+GYRG++  GRD  AD KFR+++RI V GK +  +EVF DTLN+SRDPD    +RY+SRY+LK N LEQAF+ L ++G+ MVA   +GT +  S       SE+  W  Y E+VF R
Sbjct:  210 ITIGYRGSYTIGRDAQADAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDRP-PERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTGTCAFASST---DQSEDKIWTSYTEYVFCR 324

HSP 2 Score: 67.0106 bits (162), Expect = 3.325e-11
Identity = 34/95 (35.79%), Postives = 59/95 (62.11%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI 365
            IV LNVGG  Y+T + T++   +S+   +  +    +    +K + F+DRDG LFR++L++LR  ++ LP  F E   L+REA Y++L E++ ++
Sbjct:   35 IVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129
[Close]
BLAST of BTB domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6WVG3|KCD12_MOUSE (BTB/POZ domain-containing protein KCTD12 OS=Mus musculus OX=10090 GN=Kctd12 PE=1 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 6.109e-31
Identity = 60/119 (50.42%), Postives = 80/119 (67.23%), Query Frame = 3 
Query:  387 ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            IT+GYRG++  GRD  AD KFR+++RI V GK +  +EVF DTLN+SRDPD    +RY+SRY+LK N LEQAF+ L ++G+ MVA   +GT +  S       SE+  W  Y E+VF R
Sbjct:  212 ITIGYRGSYTIGRDAQADAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDRP-PERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTGTCAFASST---DQSEDKIWTSYTEYVFCR 326

HSP 2 Score: 65.4698 bits (158), Expect = 1.058e-10
Identity = 33/95 (34.74%), Postives = 58/95 (61.05%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI 365
            IV LNVGG  Y+T + T++   +S+   +  +    +    +K + F+DRDG  FR++L++LR  ++ LP  F E   L+REA Y++L E++ ++
Sbjct:   35 IVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFFFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129
[Close]
BLAST of BTB domain-containing protein vs. TrEMBL
Match: B4II53 (GM23149 OS=Drosophila sechellia OX=7238 GN=Dsec\GM23149 PE=4 SV=1)

HSP 1 Score: 261.151 bits (666), Expect = 1.879e-83
Identity = 128/227 (56.39%), Postives = 159/227 (70.04%), Query Frame = 3 
Query:   75 MDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMM----NQIDEKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            M  I+ LNVGG +Y T   TL +  N++  EL  +   S P     + F+DRDG LFR++L+FLR   + LP  F E Q L REA ++KLT M+    N+ D + P  IT+GYRG+F FG+DGLADVKFRKLSRILV G+V  CREVF DTLN+SRDPD+G  DRY+SR+FLKH  +EQAF+ L+D GY M  SCGSGT  S +E KPG D+EEN+W HYNEFVF R
Sbjct:    1 MPEIIELNVGGVSYTTTLATLQQDKNTLLAELFGEGRDSLPKDSKGRYFLDRDGVLFRYILDFLRDKALHLPEGFRERQRLLREAEHFKLTAMLECIRNERDARPPGCITIGYRGSFQFGKDGLADVKFRKLSRILVCGRVAQCREVFGDTLNESRDPDHGGTDRYTSRFFLKHCYIEQAFDNLHDHGYRMAGSCGSGTAGSAAEPKPGVDTEENRWNHYNEFVFIR 227
[Close]
BLAST of BTB domain-containing protein vs. TrEMBL
Match: B4R1Q0 (GD20024 OS=Drosophila simulans OX=7240 GN=Dsim\GD20024 PE=4 SV=1)

HSP 1 Score: 261.151 bits (666), Expect = 1.879e-83
Identity = 128/227 (56.39%), Postives = 159/227 (70.04%), Query Frame = 3 
Query:   75 MDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMM----NQIDEKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            M  I+ LNVGG +Y T   TL +  N++  EL  +   S P     + F+DRDG LFR++L+FLR   + LP  F E Q L REA ++KLT M+    N+ D + P  IT+GYRG+F FG+DGLADVKFRKLSRILV G+V  CREVF DTLN+SRDPD+G  DRY+SR+FLKH  +EQAF+ L+D GY M  SCGSGT  S +E KPG D+EEN+W HYNEFVF R
Sbjct:    1 MPEIIELNVGGVSYTTTLATLQQDKNTLLAELFGEGRDSLPKDSKGRYFLDRDGVLFRYILDFLRDKALHLPEGFRERQRLLREAEHFKLTAMLECIRNERDARPPGCITIGYRGSFQFGKDGLADVKFRKLSRILVCGRVAQCREVFGDTLNESRDPDHGGTDRYTSRFFLKHCYIEQAFDNLHDHGYRMAGSCGSGTAGSAAEPKPGVDTEENRWNHYNEFVFIR 227
[Close]
BLAST of BTB domain-containing protein vs. TrEMBL
Match: B4NFR6 (BTB_2 domain-containing protein OS=Drosophila willistoni OX=7260 GN=Dwil\GK22689 PE=4 SV=1)

HSP 1 Score: 259.61 bits (662), Expect = 8.456e-83
Identity = 128/229 (55.90%), Postives = 160/229 (69.87%), Query Frame = 3 
Query:   75 MDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDP--NTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI----DEKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            M  I+ LNVGG NY T   TLL+   ++  EL  +++  D        + F+DRDG LFR++L+FLR   + LP  F E Q L REA ++KLT M++ I    D + P  IT+GYRG+F FG+DGLADVKFRKLSRILV G+V  CREVF DTLN+SRDPD+G  DRY+SR+FLKH  +EQAF+ L+D GY M  SCGSGT  S +E KPG D+EEN+W HYNEFVF R
Sbjct:    1 MPEIIELNVGGVNYTTTLATLLQDKTTLLHELFAEATGRDALAKDSKGRYFLDRDGVLFRYILDFLRDKALNLPEGFRERQRLLREAEHFKLTAMLDSIKGERDARPPGCITIGYRGSFQFGKDGLADVKFRKLSRILVCGRVAQCREVFGDTLNESRDPDHGGPDRYTSRFFLKHCFIEQAFDHLHDHGYRMAGSCGSGTAGSAAEPKPGVDTEENRWNHYNEFVFIR 229
[Close]
BLAST of BTB domain-containing protein vs. TrEMBL
Match: A0A2A4IXI0 (BTB_2 domain-containing protein OS=Heliothis virescens OX=7102 GN=B5V51_10689 PE=4 SV=1)

HSP 1 Score: 259.225 bits (661), Expect = 1.254e-82
Identity = 127/230 (55.22%), Postives = 164/230 (71.30%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPN---TGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQIDEKSP-------SVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            ++ LNVGG +Y T + TLL+      P+ L  ++  DP+       +IF DRDG LFR+VL++LR G + LP  F E + L REA +Y+L  + N + +  P         ITVGYRG+FAFGRDGLADVKFRKLSRILV GKVN CR+VF +TLN+SRDPD+G  DRY+SR+FLKH+ +EQAF+MLY+ G+ + ASCGSGT    +E+KPG DSEEN+W HYNEFVF+R
Sbjct:    8 VLELNVGGVHYATTRDTLLR-----EPDSLPAAALQDPDHPRDARGRIFFDRDGVLFRYVLDYLRDGGLVLPECFREHKRLAREAKHYRLAGLENAVRDADPRPPNREKGCITVGYRGSFAFGRDGLADVKFRKLSRILVCGKVNLCRDVFGETLNESRDPDHGLADRYTSRFFLKHSFIEQAFDMLYENGFKLTASCGSGTAGGAAELKPGVDSEENRWNHYNEFVFTR 232
[Close]
BLAST of BTB domain-containing protein vs. TrEMBL
Match: Q9VDH3 (GH08630p OS=Drosophila melanogaster OX=7227 GN=Ktl PE=1 SV=1)

HSP 1 Score: 257.684 bits (657), Expect = 4.051e-82
Identity = 127/227 (55.95%), Postives = 158/227 (69.60%), Query Frame = 3 
Query:   75 MDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI----DEKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            M  I+ LNVGG +Y T   TLL+  +++  EL  +   S       + F+DRDG LFR++L+FLR   + LP  F E Q L REA ++KLT M+  I    D + P  IT+GYRG+F FG+DGLADVKFRKLSRILV G+V  CREVF DTLN+SRDPD+G  DRY+SR+FLKH  +EQAF+ L+D GY M  SCGSGT  S +E KPG D+EEN+W HYNEFVF R
Sbjct:    1 MPEIIELNVGGVSYTTTLATLLQDKSTLLAELFGEGRDSLAKDSKGRYFLDRDGVLFRYILDFLRDKALHLPEGFRERQRLLREAEHFKLTAMLECIRSERDARPPGCITIGYRGSFQFGKDGLADVKFRKLSRILVCGRVAQCREVFGDTLNESRDPDHGGTDRYTSRFFLKHCYIEQAFDNLHDHGYRMAGSCGSGTAGSAAEPKPGVDTEENRWNHYNEFVFIR 227
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Cavefish
Match: kctd12b (potassium channel tetramerisation domain containing 12b [Source:ZFIN;Acc:ZDB-GENE-050417-104])

HSP 1 Score: 169.859 bits (429), Expect = 8.080e-51
Identity = 97/247 (39.27%), Postives = 142/247 (57.49%), Query Frame = 3 
Query:   81 SIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI-------------------DEKSPSV------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            SI+ LNVGG  Y+T  +TL    +S+  E+  + S        K + F+DRDG LFR++L+++R  ++ LP +F E   L+REA Y+ L E++  +                   +E SPS       IT+GYRG++  GRD   D KFR+++RI+V GK +  +EVF +TLN+SRDPD    +RY+SRY+LK   LEQAF+ L DAG+ MVA      NS+G+       +++  W  Y E+VF R
Sbjct:   14 SIIELNVGGQVYITRYSTLTSVPDSLLWEMFSQKSQKGLARDTKGRFFVDRDGFLFRYILDYMRDQQLVLPDHFPERGRLQREAEYFNLPELVKLLAPKISKQNSLGDEGCQSDPEESSPSADTRSGFITIGYRGSYTLGRDSQTDAKFRRVARIMVCGKTSLAKEVFGETLNESRDPDRP-PERYTSRYYLKFTFLEQAFDKLADAGFHMVAC-----NSTGTCAFAHDQTDDKIWTSYTEYVFYR 254
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Cavefish
Match: KCTD12 (potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678])

HSP 1 Score: 162.155 bits (409), Expect = 1.439e-47
Identity = 99/277 (35.74%), Postives = 148/277 (53.43%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI---------------------------------------------------DEKSPSV----ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENK-WQHYNEFVFSR 743
            +V LNVGG  Y+T ++TL+   +S+   +  + S ++ +T  K + F+DRDG LFR++L++LR G + LP  F E   L+REA +++L E+  ++                                                   + +SPS+    IT+GYRG++  GRD   D KFR+++RI V GK +  +EVF DTLN+SRDPD    +RY+SRY+LK+N LEQAF+ L + G+ MVA   +GT +  S      D  E+K W  Y E+VF R
Sbjct:   14 LVELNVGGQVYVTRRSTLVSVPDSLLGRMFGQQSPAELSTDTKGRFFLDRDGFLFRYILDYLRDGNLVLPDYFRERAGLRREAEFFQLRELARRLAPQVSKENSISDEAQGEHDHDDVCGGGSVGSIGSIGSALPTTSTTSTIALTEPRSPSLKCGYITIGYRGSYTIGRDIQTDAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDRP-PERYTSRYYLKYNFLEQAFDRLAEMGFRMVACSSTGTCAYTS-----NDPNEDKIWTSYTEYVFCR 284
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Cavefish
Match: kctd12.1 (potassium channel tetramerisation domain containing 12.1 [Source:ZFIN;Acc:ZDB-GENE-030902-5])

HSP 1 Score: 158.688 bits (400), Expect = 2.977e-46
Identity = 95/264 (35.98%), Postives = 141/264 (53.41%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI-------------------------------------------DEKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            I+ LNVGG  Y+T   TL+   +S+   +  K +  +    +K + F+DRDG LFR++L++LR   + LP  F E   L+REA +++L E+  ++                                           ++KS   ITVGYRG++  GRD   D KFR+++RI V GK +  +EVF +TLN+SRDPD    +RY+SRY+LK+N LEQAF+ L + G+ MVA   +GT +  S     + SE+  W  Y E+VF R
Sbjct:   16 IIELNVGGQVYVTRHRTLVSVPDSLLWSMFSKKTPRELARDSKGRFFLDRDGFLFRYILDYLRDLNLVLPDYFPEKSRLQREAEFFQLRELSKRLSPRVSKENSISEDLSHISSDWDEAPGPGGALLPPSTSPSPSQENKKSCGYITVGYRGSYTIGRDIQTDAKFRRVARITVCGKTSLAKEVFGETLNESRDPDRP-PERYTSRYYLKYNFLEQAFDKLTEFGFRMVACSSTGTCAYSS----NEPSEDKVWTSYTEYVFCR 274
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Cavefish
Match: kctd8 (potassium channel tetramerization domain containing 8 [Source:NCBI gene;Acc:103044733])

HSP 1 Score: 150.599 bits (379), Expect = 4.232e-43
Identity = 90/266 (33.83%), Postives = 141/266 (53.01%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSD-PNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMM-------------------NQIDEKSPS----------------------------VITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVF 737
            ++ LNVGG  Y+T + TLL   ++    +  + +  + P     + FIDRDG LFR+VL+FLR  ++ LP +F E + L+REA +++L E++                   + I+E S S                             IT+GYRG++   RD   D KFR+++RI+V G++   +EVF DTLN+SRDPD    ++Y+SR++LK   LEQAF+ L ++G+ MVA      NS+G+     Q  ++  W  Y E++F
Sbjct:   22 VIELNVGGQVYVTKRATLLSVPDTPLHAMFARRAPRELPRDSRGRFFIDRDGFLFRYVLDFLRDRQLVLPEHFPERERLQREAEHFQLGELLRILGPKVAKQGSLNDEGCQSDIEESSQSSELQLGRTSGSGAVSGPFSSTAQDKRSGFITIGYRGSYTMVRDNQTDAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRP-PEKYTSRFYLKFTHLEQAFDRLSESGFNMVA-----CNSTGTAAFVNQYRDDKIWSSYTEYIF 281
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Cavefish
Match: kctd8 (potassium channel tetramerization domain containing 8 [Source:NCBI gene;Acc:103044733])

HSP 1 Score: 150.214 bits (378), Expect = 1.248e-42
Identity = 90/266 (33.83%), Postives = 141/266 (53.01%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSD-PNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMM-------------------NQIDEKSPS----------------------------VITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVF 737
            ++ LNVGG  Y+T + TLL   ++    +  + +  + P     + FIDRDG LFR+VL+FLR  ++ LP +F E + L+REA +++L E++                   + I+E S S                             IT+GYRG++   RD   D KFR+++RI+V G++   +EVF DTLN+SRDPD    ++Y+SR++LK   LEQAF+ L ++G+ MVA      NS+G+     Q  ++  W  Y E++F
Sbjct:   22 VIELNVGGQVYVTKRATLLSVPDTPLHAMFARRAPRELPRDSRGRFFIDRDGFLFRYVLDFLRDRQLVLPEHFPERERLQREAEHFQLGELLRILGPKVAKQGSLNDEGCQSDIEESSQSSELQLGRTSGSGAVSGPFSSTAQDKRSGFITIGYRGSYTMVRDNQTDAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRP-PEKYTSRFYLKFTHLEQAFDRLSESGFNMVA-----CNSTGTAAFVNQYRDDKIWSSYTEYIF 281
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Sea Lamprey
Match: kctd12b (potassium channel tetramerisation domain containing 12b [Source:ZFIN;Acc:ZDB-GENE-050417-104])

HSP 1 Score: 120.553 bits (301), Expect = 3.864e-32
Identity = 63/126 (50.00%), Postives = 83/126 (65.87%), Query Frame = 3 
Query:  369 EKSPSVITVGYRGTFAFGRDG-LADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            E+ P  ITVGYRG++   RD   AD KFR+++RI+V GK    +EVF +TLN+SRDPD    +RY+SRY+LK   LEQAF+ L +AG+ MVA      NS+GS    G  SE+  W +Y E+VF R
Sbjct:  190 ERRPGFITVGYRGSYTVARDSQAADAKFRRVARIMVCGKTALAKEVFGETLNESRDPDRP-PERYTSRYYLKFTFLEQAFDRLAEAGFHMVA-----CNSNGSAAYAGDLSEDRIWTNYTEYVFFR 309

HSP 2 Score: 63.5438 bits (153), Expect = 8.843e-12
Identity = 37/101 (36.63%), Postives = 57/101 (56.44%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNS----IFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQIDEK 374
            ++ LNVGG  Y+T   TL+   +S    IF  L+D++            FIDRDG LFR++L++LR  R+ LP +F E   L+REA ++ L E+   +  +
Sbjct:   21 VIELNVGGQVYLTRCATLVSAPDSLLGRIFSCLIDRAC---RFRTLLCYFIDRDGFLFRYILDYLRDNRLVLPEHFPERSRLQREAEFFGLPELARSLAPR 118
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Sea Lamprey
Match: kctd6a (potassium channel tetramerization domain containing 6a [Source:ZFIN;Acc:ZDB-GENE-050208-474])

HSP 1 Score: 72.4034 bits (176), Expect = 3.524e-15
Identity = 43/130 (33.08%), Postives = 64/130 (49.23%), Query Frame = 3 
Query:   75 MDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQIDEKSPSVITVGYRGTFAFGRDGLADVKFRKLSR 464
            M   V LNVGG  Y T + TL + ++S+   +                FIDRDG LFR+VL FLR   + LP +F E+ LL++EA +Y++ +++  ++E  P      Y  T             RKLS+
Sbjct:   10 MSEPVTLNVGGHLYSTSRATLTRYSDSMLGAMF-SGDLPTARDAQGHYFIDRDGPLFRYVLNFLRTSELTLPQDFKEIDLLRKEADFYQIEQLIQCLNEPKPLYALDTYEETVELA-------SIRKLSK 131
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Sea Lamprey
Match: kctd7 (potassium channel tetramerization domain containing 7 [Source:NCBI gene;Acc:735248])

HSP 1 Score: 53.1434 bits (126), Expect = 1.807e-8
Identity = 33/99 (33.33%), Postives = 51/99 (51.52%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQIDEKSP 380
            +V LNVGGT++ TL +TL  C  S+   +        P     + FIDRD + F  +L FLR G  E+P +    + + REA Y+ L  ++  ++   P
Sbjct:    4 VVQLNVGGTHFATLLSTLRSCEGSMLAAMF-SGRHRLPRDHVGRFFIDRDPAYFGDILNFLRSG--EVPCH-ERARGVHREAHYFGLQPLLACLETLQP 98
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Nematostella
Match: EDO34699 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNM1])

HSP 1 Score: 183.726 bits (465), Expect = 7.299e-57
Identity = 102/234 (43.59%), Postives = 140/234 (59.83%), Query Frame = 3 
Query:   75 MDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI----------DEKSPS-VITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            + ++V LNVGG  Y T   TLLK + S+   +        P     + FIDRDG LFR++L++LR  ++ LP  F E + L  EA ++KL  M+  I          D+  PS  I++G RGT+AFGRDG+ADVKFRKL RILV G V   REVF D+LN++RDPD     RY++R++LKH+ LE+AF+ L + GY MV S   G            ++EE KW H+N++VF R
Sbjct:   13 LPAVVELNVGGQLYTTSLPTLLKDSESLLSSMFSGRQ-KIPRDSRGRFFIDRDGVLFRYILDYLRNCKLALPEGFNERERLTMEAEHFKLKGMVRAIQREKDNIKSTDKGRPSGYISIGVRGTYAFGRDGVADVKFRKLQRILVCGNVALAREVFGDSLNETRDPDRD-DQRYTNRFYLKHSYLEKAFDQLMEKGYTMVTSSAGGAGYD-------PENEETKWNHFNDYVFFR 237
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Nematostella
Match: EDO38835 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBR2])

HSP 1 Score: 155.606 bits (392), Expect = 6.407e-46
Identity = 91/234 (38.89%), Postives = 136/234 (58.12%), Query Frame = 3 
Query:   87 VHLNVGGTNYMTLKTTLLKCTNSIFPELLD--KSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQID-----EKSPSV--------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            + LNVGG  + T   TL +  +S+   +    +S     N+G  K FIDRDG LFR++L++LR   + +P  F E++ LK EA +Y+L ++  ++D     E SP +        I++  R TFAFGR G ADV FRKL RI V G+V+  +E F D+LN +RDP+      Y+SR++LK+N LE+AF  L+ +G+ +V+S G  T    S       S+E KW+H+  + F R
Sbjct:    5 IELNVGGKYFSTSVFTLTRIKDSLLGRIFSGRQSELDKDNSG--KYFIDRDGFLFRYILDYLRSKALHIPEKFDEIERLKMEADFYELEDLRQRLDRLTSGEISPKISEGGKHGYISLHIRSTFAFGRSGQADVNFRKLQRICVCGRVSLLKEAFGDSLNMTRDPNQN-AMHYTSRFYLKYNQLERAFMQLHSSGFEIVSSEGGKTGDVAS-----PKSDEEKWEHFTIYYFVR 230
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Nematostella
Match: EDO34594 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNY3])

HSP 1 Score: 68.1662 bits (165), Expect = 1.172e-14
Identity = 37/95 (38.95%), Postives = 56/95 (58.95%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLD-KSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI 365
            IV+LNVGG  Y T   TL +C +S+   +   + + +    G    FIDRDGSLFR++L FLR   + LP +F E Q L  EA +Y++ +++  +
Sbjct:    1 IVNLNVGGYVYTTSYKTLTRCRDSMLGAMFSGRQNLARDTRG--NFFIDRDGSLFRYILNFLRTSELCLPDSFDEFQQLSLEADFYQIEDLIKAL 93
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Nematostella
Match: EDO32194 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVR4])

HSP 1 Score: 62.003 bits (149), Expect = 2.551e-12
Identity = 35/102 (34.31%), Postives = 60/102 (58.82%), Query Frame = 3 
Query:   60 DKTLKMDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI 365
            D T+   +I+ LNVGG ++ T   TL    +S+   +       + ++  +  FIDRDG+LFR++L FLR   + LP+NF + +LL  EA +Y++  ++ +I
Sbjct:    2 DATVDFPAIIDLNVGGNHFTTTLLTLTTFPDSMLGSMFSGRIPVNRDSNGR-FFIDRDGTLFRYILNFLRSNVLSLPANFKDYELLLNEADFYQIEPLIEEI 102
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Nematostella
Match: EDO28987 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVR4])

HSP 1 Score: 62.003 bits (149), Expect = 2.551e-12
Identity = 35/102 (34.31%), Postives = 60/102 (58.82%), Query Frame = 3 
Query:   60 DKTLKMDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI 365
            D T+   +I+ LNVGG ++ T   TL    +S+   +       + ++  +  FIDRDG+LFR++L FLR   + LP+NF + +LL  EA +Y++  ++ +I
Sbjct:    2 DATVDFPAIIDLNVGGNHFTTTLLTLTTFPDSMLGSMFSGRIPVNRDSNGR-FFIDRDGTLFRYILNFLRSNVLSLPANFKDYELLLNEADFYQIEPLIEEI 102
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Medaka
Match: kctd12.2 (potassium channel tetramerisation domain containing 12.2 [Source:ZFIN;Acc:ZDB-GENE-060117-4])

HSP 1 Score: 169.859 bits (429), Expect = 7.161e-51
Identity = 101/260 (38.85%), Postives = 146/260 (56.15%), Query Frame = 3 
Query:   66 TLKMDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSD-PNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQIDE-----------------------------KSPS----VITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            + + D+ + LNVGG  Y+T   TL    NS+      +SS S+ P     + F DRDG LFR++L++LR   + LP  F E + L+REA +++L E+  ++ E                             +SP      IT+GYRG++  GRD  AD KFR+++RI V  K++  +EVF +TLN+SRDPD    D+Y++RY+LK+N LEQAF+ L +AG+ MVA   +GT S GS   PG+D     W  Y E+VF R
Sbjct:    3 SARADATLELNVGGQVYVTRLETLTAVPNSLLWVRFTQSSPSELPKDRHGRFFFDRDGHLFRYILDYLRDTELFLPEFFKERKRLQREADFFQLPELAKRLAEAAYPEDGGDPEEAELGSPVCSSTSSERALRSPGSGSGYITIGYRGSYTIGRDIQADAKFRRVARITVCSKISLAKEVFGETLNESRDPDRP-PDKYTARYYLKYNFLEQAFDRLAEAGFHMVACNSTGTCSYGSN-DPGED---KLWTSYTEYVFCR 257
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Medaka
Match: kctd12.1 (potassium channel tetramerisation domain containing 12.1 [Source:ZFIN;Acc:ZDB-GENE-030902-5])

HSP 1 Score: 157.532 bits (397), Expect = 9.856e-46
Identity = 101/279 (36.20%), Postives = 146/279 (52.33%), Query Frame = 3 
Query:   60 DKTLKMDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKL------------------TEMMNQIDE--------------------------KSPSV-------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENK-WQHYNEFVF 737
            D +     I+ LNVGG  Y+T   TL+   +S+   +  K S  +    +K + F+DRDG LFR++L++LR   + LP  F E   L+REA +++L                   E++NQ D                           +SPS+       IT+GYRG++  GRD   D KFR+++RI V GK +  +EVF +TLN+SRDPD    +RY+SRY+LK+N LEQAF+ L +AG+ MVA   +GT +  S      D  E+K W  Y E+VF
Sbjct:   15 DPSAAFSEIIELNVGGQVYVTRHKTLVAVPDSLLWNMFSKKSPKELARDSKGRFFLDRDGFLFRYILDYLRDLNLVLPDYFPEKSRLQREADFFQLRDLAKRLSPRVSKDNSICEEIINQSDTEDGGLQCCSTSGGIDTLRAASVSGAMRSPSLDSRKSGYITIGYRGSYTIGRDIQTDAKFRRVARITVCGKTSLAKEVFGETLNESRDPDRP-PERYTSRYYLKYNFLEQAFDKLTEAGFHMVACSSTGTCAYTS-----NDPNEDKIWTSYTEYVF 287
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Medaka
Match: kctd12b (BTB/POZ domain-containing protein KCTD12 [Source:NCBI gene;Acc:101170105])

HSP 1 Score: 159.073 bits (401), Expect = 1.576e-44
Identity = 95/270 (35.19%), Postives = 141/270 (52.22%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQIDEK-------------------SPSV------------------------------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            I+ LNVGG  Y+T  +TL    +S+  E+  + S        K + F+DRDG LFR++L+++R  ++ LP +F E   L+REA ++ L E++ Q+  K                   SP +                              IT+GYRG++  GRD   D KFR+++RI+V GK +  +EVF +TLN+SRDPD    +RY+SRY+LK   LEQAF+ L DAG+ MVA   +GT +   E      +++  W  Y E+VF R
Sbjct:   18 IIELNVGGQVYITRYSTLTSVPDSLLWEMFSQKSAKGLARDTKGRFFVDRDGFLFRYILDYMRDQQLVLPDHFPERGRLQREAEFFNLPELVKQLAPKISKQNSLGDEGCQSDPEDSSPGMDTVRSLGSLGATATCSSLGPVAMDGKRSGFITIGYRGSYTLGRDSHTDAKFRRVARIMVCGKTSLAKEVFGETLNESRDPDRP-PERYTSRYYLKFTFLEQAFDKLADAGFHMVACNSTGTCAFAHE-----QTDDKIWTSYTEYVFYR 281
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Medaka
Match: kctd16b (potassium channel tetramerization domain containing 16 [Source:NCBI gene;Acc:101171513])

HSP 1 Score: 151.369 bits (381), Expect = 5.694e-42
Identity = 96/259 (37.07%), Postives = 140/259 (54.05%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLD--KSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQIDEK---------------------------SPSV---------ITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            +V LNVGG  Y T   TL+   +S+  +L    K + +D     K + FIDRDG LFR+VL++LR  +V LP +F E   L++EA Y++L +++  +  +                            PS+         ITVGYRG+   GR+   D KFR++ RIL+ G+V   +EVF +TLN+SRDPD    DRY+SR++LK   LE++F+ML + G+ MVA C S   +S       Q +E+  W  Y E+VF R
Sbjct:   28 VVELNVGGQVYYTRHATLVSTPSSLLGKLFSSKKDAGNDLARDPKGRYFIDRDGFLFRYVLDYLRDKQVVLPDHFPEKGRLRKEAEYFQLPDLVKLLTTEDVKFSPDDYILSDYEDGSQGSDHRQCPPPSLVPADRKSGYITVGYRGSCTTGRESQTDAKFRRVPRILICGRVALAKEVFGETLNESRDPDRT-PDRYTSRFYLKFKHLERSFDMLSECGFQMVA-CNSSVTASFV----NQHTEDKNWSSYTEYVFYR 280
[Close]
BLAST of BTB domain-containing protein vs. Ensembl Medaka
Match: kctd16a (BTB/POZ domain-containing protein KCTD16 [Source:NCBI gene;Acc:101167549])

HSP 1 Score: 126.331 bits (316), Expect = 9.439e-33
Identity = 87/256 (33.98%), Postives = 136/256 (53.12%), Query Frame = 3 
Query:   84 IVHLNVGGTNYMTLKTTLLKCTNSIFPELLD--KSSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMM-----------------------NQIDEKSPS---------VITVGYRGTFAF-GRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSR 743
            ++ LNVGG  Y T   TL    NS+  +L    K S +D +   + + FIDRDG LFR+VL++LR  +V LP +F E   LKREA +++L E++                       +Q  E+  S          ITV + G  A   R+G  + K +KL RI +S ++   +EVF D LN+++D D    DRY+ R++LK   LE+AF+ML + G+ +VA   S T+SS      G  +++  W ++++++F R
Sbjct:   25 VIELNVGGQVYYTRHATLTSIPNSLLGKLFSNKKGSLNDLSRDLRGRYFIDRDGFLFRYVLDYLRDKQVVLPDHFPERGRLKREAEHFQLPELVKLLSADESKLFPDDLYCSDLEDASQCSERFYSSFSFDRRYGYITVTFIGACAARSREGHTETKNKKLPRIFISSRIGLAKEVFGDALNENKDADRP-SDRYTCRFYLKFKHLERAFDMLSECGFHIVACNTSLTSSSM-----GHYTDDRAWSNHSQYIFYR 274
[Close]
BLAST of BTB domain-containing protein vs. Planmine SMEST
Match: SMESG000014239.1 (SMESG000014239.1)

HSP 1 Score: 466.077 bits (1198), Expect = 5.589e-168
Identity = 225/225 (100.00%), Postives = 225/225 (100.00%), Query Frame = 3 
Query:   75 MDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQIDEKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSRLN 749
            MDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQIDEKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSRLN
Sbjct:    1 MDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQIDEKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSRLN 225
[Close]
BLAST of BTB domain-containing protein vs. Planmine SMEST
Match: SMESG000017289.1 (SMESG000017289.1)

HSP 1 Score: 238.81 bits (608), Expect = 1.575e-77
Identity = 125/226 (55.31%), Postives = 163/226 (72.12%), Query Frame = 3 
Query:   78 DSIVHLNVGGTNYMTLKTTLL-KCTNSIFPELLDK--SSFSDPNTGAK-KIFIDRDGSLFRFVLEFLRI-----GRVELPSNFGELQLLKREAIYYKLTEMMNQIDEK----SPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGF----GDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEE 704
            D +V LNVGG  Y + K+T + +  NS    L+ +     +D    +K ++FIDR+G+LFRF+++FLR       +  LP  F E   LK EA+Y+ + EM+  ++++     P+VIT+GYRGTFAFGRDGLADVKFRKLSRILVSGKV+ C+EVF+DTLN SRDPD G+    GDRYS+R+FLKHN+LEQAF+ LY  GY MV SCGSGTNS+GS+ +PGQDSEE
Sbjct:    7 DKVVELNVGGITYASFKSTFVDQYPNSKLASLVLQYVKQPTDSLVDSKNRLFIDRNGALFRFIIDFLRCKKNKESKFNLPDTFRETSALKNEAVYFGINEMVENLEKRIQHIGPTVITLGYRGTFAFGRDGLADVKFRKLSRILVSGKVSPCKEVFQDTLNMSRDPDCGYAGSKGDRYSARFFLKHNVLEQAFDALYLCGYKMVGSCGSGTNSAGSDNRPGQDSEE 232
[Close]
BLAST of BTB domain-containing protein vs. Planmine SMEST
Match: SMESG000025160.1 (SMESG000025160.1)

HSP 1 Score: 234.187 bits (596), Expect = 1.450e-75
Identity = 127/262 (48.47%), Postives = 161/262 (61.45%), Query Frame = 3 
Query:   78 DSIVHLNVGGTNYMTLKTTLLKCTNSIFPELL----------------DKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQID----------------EKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLNDSRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGSEIKPGQDSEENKWQHYNEFVFSRLN*PTYLP 767
            + IV LNVGG +Y TL +TL+K  NS   ++                 +KS    P       FIDRDG LF+F+LE+LR  R+ LP NF E+  LK E  +YK+      ID                +KS S ITVGY+GTFAFGRDG+ DVKFRKL RIL++G  + CR VF+DTLND+RDP+    DRYSSR++LKHN LE AF+MLY  G+ MV SCGS T+   SE KP   SEE++WQHYNEF+F+R + P + P
Sbjct:   26 EKIVQLNVGGQDYSTLLSTLIKQPNSWLAKMFYPLQNSFDLSFSVSLPNKSLVDLPKDSDNHYFIDRDGYLFQFILEYLRTDRLFLPDNFDEITRLKNEFQFYKIKFTDLNIDSHKLHISRDIALSSWTDKSKS-ITVGYQGTFAFGRDGVVDVKFRKLYRILIAGHASLCRWVFEDTLNDNRDPERCSEDRYSSRFYLKHNSLETAFDMLYAKGFDMVGSCGSNTHGGSSETKPSHHSEESRWQHYNEFIFARRSYPFFSP 286
[Close]
BLAST of BTB domain-containing protein vs. Planmine SMEST
Match: SMESG000071877.1 (SMESG000071877.1)

HSP 1 Score: 62.7734 bits (151), Expect = 5.130e-11
Identity = 66/228 (28.95%), Postives = 94/228 (41.23%), Query Frame = 3 
Query:   72 KMDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQ--------------------------IDEKSPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKD--TLNDSRDPDNGFG-DRYSSRY----FLKHNILEQAFEMLYDAGYAMVASCGSG 656
            +  + VHL+VGGT Y T   TL K TNS   +L + +     +   +  FIDRDG+LFR +L FLR  +  L  +F EL  L  EA Y++L  M+ Q                          I+ K P  +           R  +         RIL+SG       +F +     +   P+N    D+Y  R     +L  N +E   E ++  G   VASCG G
Sbjct:   55 RWTAPVHLDVGGTIYTTTLITLTKYTNSKLAQLFNGTLPVVLDELKQHYFIDRDGTLFRHILNFLRCSQCHLKPDFPELDQLLEEASYFELEPMLEQLKNLKSIRDKQTGNSLVPDNSNAKFDIESKKPKQLKRTTTCQVNQNRCLVVSTSPELQERILISGSRILINRIFPNLQAAIEKYSPNNWSSTDKYWIRLPLNGYLSMNSIE-TLETIFQFGMEFVASCGLG 281
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BLAST of BTB domain-containing protein vs. Planmine SMEST
Match: SMESG000017037.1 (SMESG000017037.1)

HSP 1 Score: 57.3806 bits (137), Expect = 2.560e-9
Identity = 36/95 (37.89%), Postives = 50/95 (52.63%), Query Frame = 3 
Query:   93 LNVGGTNYMTLKTTLLKCTNSIFPEL----LDKSSFSDPNTGAKKIFIDRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQI 365
            +NVGG  + T  +TL +  NS+   +    +  S   D N     IF+DRDG LF +VL FLR G + LP  F     L+ EA YY L E++  +
Sbjct:   20 INVGGIIHTTTLSTLCRYPNSMIARMFIGSIPPSQSIDSN---GNIFLDRDGVLFGYVLNFLRSGVLTLPDGFHSFNSLQIEADYYGLDELLEAL 111
The following BLAST results are available for this feature:
BLAST of BTB domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KCTD161.354e-4337.84potassium channel tetramerization domain containin... [more]
KCTD161.354e-4337.84potassium channel tetramerization domain containin... [more]
KCTD88.537e-4033.56potassium channel tetramerization domain containin... [more]
KCTD121.211e-3150.42potassium channel tetramerization domain containin... [more]
KCTD154.469e-1828.07potassium channel tetramerization domain containin... [more]
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BLAST of BTB domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
VM106R.18.542e-5938.95pep chromosome:WBcel235:II:10827716:10829556:-1 ge... [more]
F32B4.53.408e-1542.42pep chromosome:WBcel235:I:11517769:11520660:-1 gen... [more]
B0281.65.878e-1340.78pep chromosome:WBcel235:II:2301308:2302229:-1 gene... [more]
ZC239.31.649e-1236.28pep chromosome:WBcel235:II:3216081:3216600:1 gene:... [more]
F22E5.122.132e-1239.00pep chromosome:WBcel235:II:2646328:2646843:-1 gene... [more]
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BLAST of BTB domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ktl1.364e-8555.95gene:FBgn0038839 transcript:FBtr0347575[more]
Ktl1.364e-8555.95gene:FBgn0038839 transcript:FBtr0083986[more]
twz4.360e-1136.17gene:FBgn0034636 transcript:FBtr0071692[more]
twz5.804e-1136.17gene:FBgn0034636 transcript:FBtr0308642[more]
CG94671.634e-734.38gene:FBgn0037758 transcript:FBtr0082156[more]
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BLAST of BTB domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kctd12.25.073e-4937.27potassium channel tetramerisation domain containin... [more]
kctd12.25.073e-4937.27potassium channel tetramerisation domain containin... [more]
kctd12.18.728e-4736.90potassium channel tetramerisation domain containin... [more]
kctd12.18.728e-4736.90potassium channel tetramerisation domain containin... [more]
kctd12b1.042e-4535.66potassium channel tetramerisation domain containin... [more]
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BLAST of BTB domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zmat36.877e-4736.53zinc finger matrin-type 3 [Source:Xenbase;Acc:XB-G... [more]
ENSXETT00000022598.18.614e-4636.65pep primary_assembly:Xenopus_tropicalis_v9.1:KV461... [more]
lsm113.140e-4337.84LSM11, U7 small nuclear RNA associated [Source:Xen... [more]
ENSXETT00000008990.12.173e-4136.84potassium channel tetramerization domain containin... [more]
kctd121.424e-3150.42potassium channel tetramerization domain containin... [more]
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BLAST of BTB domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kctd12b3.339e-4837.77potassium channel tetramerisation domain containin... [more]
Kctd12b3.339e-4837.77potassium channel tetramerisation domain containin... [more]
Kctd164.628e-4437.07potassium channel tetramerisation domain containin... [more]
Kctd164.628e-4437.07potassium channel tetramerisation domain containin... [more]
Kctd128.644e-3250.42potassium channel tetramerisation domain containin... [more]
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BLAST of BTB domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5DTY9|KCD16_MOUSE3.238e-4337.07BTB/POZ domain-containing protein KCTD16 OS=Mus mu... [more]
sp|Q68DU8|KCD16_HUMAN6.505e-4337.84BTB/POZ domain-containing protein KCTD16 OS=Homo s... [more]
sp|Q6ZWB6|KCTD8_HUMAN4.100e-3933.56BTB/POZ domain-containing protein KCTD8 OS=Homo sa... [more]
sp|Q96CX2|KCD12_HUMAN5.817e-3150.42BTB/POZ domain-containing protein KCTD12 OS=Homo s... [more]
sp|Q6WVG3|KCD12_MOUSE6.109e-3150.42BTB/POZ domain-containing protein KCTD12 OS=Mus mu... [more]
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BLAST of BTB domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
B4II531.879e-8356.39GM23149 OS=Drosophila sechellia OX=7238 GN=Dsec\GM... [more]
B4R1Q01.879e-8356.39GD20024 OS=Drosophila simulans OX=7240 GN=Dsim\GD2... [more]
B4NFR68.456e-8355.90BTB_2 domain-containing protein OS=Drosophila will... [more]
A0A2A4IXI01.254e-8255.22BTB_2 domain-containing protein OS=Heliothis vires... [more]
Q9VDH34.051e-8255.95GH08630p OS=Drosophila melanogaster OX=7227 GN=Ktl... [more]
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BLAST of BTB domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kctd12b8.080e-5139.27potassium channel tetramerisation domain containin... [more]
KCTD121.439e-4735.74potassium channel tetramerization domain containin... [more]
kctd12.12.977e-4635.98potassium channel tetramerisation domain containin... [more]
kctd84.232e-4333.83potassium channel tetramerization domain containin... [more]
kctd81.248e-4233.83potassium channel tetramerization domain containin... [more]
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BLAST of BTB domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
kctd12b3.864e-3250.00potassium channel tetramerisation domain containin... [more]
kctd6a3.524e-1533.08potassium channel tetramerization domain containin... [more]
kctd71.807e-833.33potassium channel tetramerization domain containin... [more]
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BLAST of BTB domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of BTB domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO346997.299e-5743.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO388356.407e-4638.89Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO345941.172e-1438.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO321942.551e-1234.31Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO289872.551e-1234.31Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of BTB domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kctd12.27.161e-5138.85potassium channel tetramerisation domain containin... [more]
kctd12.19.856e-4636.20potassium channel tetramerisation domain containin... [more]
kctd12b1.576e-4435.19BTB/POZ domain-containing protein KCTD12 [Source:N... [more]
kctd16b5.694e-4237.07potassium channel tetramerization domain containin... [more]
kctd16a9.439e-3333.98BTB/POZ domain-containing protein KCTD16 [Source:N... [more]
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BLAST of BTB domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000014239.15.589e-168100.00SMESG000014239.1[more]
SMESG000017289.11.575e-7755.31SMESG000017289.1[more]
SMESG000025160.11.450e-7548.47SMESG000025160.1[more]
SMESG000071877.15.130e-1128.95SMESG000071877.1[more]
SMESG000017037.12.560e-937.89SMESG000017037.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003345 ID=SMED30003345|Name=BTB domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=970bp
CAGAATGTTAAAAATATTTCAGTCTAAAATGCATATCAGCTCACATATTT
GTTGTTGATGATAAAACTCTCAAAATGGATTCTATTGTTCACCTGAATGT
TGGAGGAACCAACTATATGACTTTAAAAACCACTTTGCTCAAATGTACGA
ATTCCATTTTCCCAGAGCTTTTAGATAAATCATCCTTCTCAGATCCAAAC
ACTGGAGCAAAAAAGATCTTCATAGACAGAGACGGAAGTCTATTCAGATT
CGTATTGGAATTTTTGAGAATCGGTAGAGTTGAATTGCCATCTAATTTCG
GAGAACTTCAATTGTTGAAAAGAGAAGCTATTTACTACAAATTGACAGAA
ATGATGAATCAAATTGATGAGAAATCTCCATCAGTTATCACAGTCGGATA
TAGAGGGACTTTTGCGTTCGGACGAGATGGATTAGCCGATGTAAAATTTC
GAAAGCTTTCTAGAATTTTGGTGTCGGGAAAGGTTAATGCTTGCCGAGAA
GTTTTCAAAGACACTCTAAACGACAGCCGAGATCCTGATAATGGGTTTGG
AGATAGATATTCATCGCGATATTTCTTGAAACATAACATTTTGGAACAAG
CATTTGAAATGCTTTATGATGCCGGTTATGCTATGGTTGCCTCGTGTGGA
TCCGGTACTAATTCATCTGGCTCTGAAATAAAGCCTGGTCAAGACTCGGA
AGAAAACAAATGGCAACATTATAATGAGTTCGTATTTTCTAGATTAAATT
GACCAACTTATCTCCCAAACAATGTCCACGTAGCTACTGGTGTCGTCCTA
GAATATTAGAAATAACAATTGTTTAGTTGGATTTTAATTAATATTGATAT
GAACAAAAAAAAACATTTATCCAAACGGTTTTTTCAATTCTAAAATTCCG
AATTTTCGATGAAACTTTATTTTTGTTTATTATGTTTAGTTGAAATTTGT
TATGAAATCTTCGTCAAAAA
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protein sequence of SMED30003345-orf-1

>SMED30003345-orf-1 ID=SMED30003345-orf-1|Name=SMED30003345-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=226bp
MDSIVHLNVGGTNYMTLKTTLLKCTNSIFPELLDKSSFSDPNTGAKKIFI
DRDGSLFRFVLEFLRIGRVELPSNFGELQLLKREAIYYKLTEMMNQIDEK
SPSVITVGYRGTFAFGRDGLADVKFRKLSRILVSGKVNACREVFKDTLND
SRDPDNGFGDRYSSRYFLKHNILEQAFEMLYDAGYAMVASCGSGTNSSGS
EIKPGQDSEENKWQHYNEFVFSRLN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR000210BTB/POZ_dom
IPR003131T1-type_BTB
IPR011333SKP1/BTB/POZ_sf
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: biological process
TermDefinition
GO:0051260protein homooligomerization
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000210BTB/POZ domainSMARTSM00225BTB_4coord: 3..105
e-value: 3.6E-4
score: 29.9
IPR000210BTB/POZ domainPROSITEPS50097BTBcoord: 1..73
score: 9.641
IPR003131Potassium channel tetramerisation-type BTB domainPFAMPF02214BTB_2coord: 5..93
e-value: 5.6E-17
score: 61.9
NoneNo IPR availableGENE3DG3DSA:3.30.710.10coord: 1..104
e-value: 4.5E-28
score: 99.4
NoneNo IPR availablePANTHERPTHR14499POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAININGcoord: 3..223
NoneNo IPR availablePANTHERPTHR14499:SF82GH08630Pcoord: 3..223
NoneNo IPR availableCDDcd18367BTB_POZ_KCTD8-likecoord: 3..99
e-value: 4.45614E-25
score: 92.7395
IPR011333SKP1/BTB/POZ domain superfamilySUPERFAMILYSSF54695POZ domaincoord: 2..97