SMED30003270
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30003270 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Alignments
SMED30003270 aligns in the following genomic locations:
Homology
BLAST of SMED30003270 vs. Ensembl Human
Match: IGFALS (insulin like growth factor binding protein acid labile subunit [Source:HGNC Symbol;Acc:HGNC:5468]) HSP 1 Score: 82.8037 bits (203), Expect = 3.908e-16 Identity = 58/186 (31.18%), Postives = 99/186 (53.23%), Query Frame = 1 Query: 355 PQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 P F+ +S L L +Q + ++E Q L +L LH+ ++ L+ G F+ P + LS+NR+S + D F+ + +L+LG N L V+ F SL+ L L+ NR+ ++ F L +++ L+L+ N L IK + L LQ L+L +N I + AF+ LK+L++++L N Sbjct: 129 PAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHN 314 HSP 2 Score: 52.7582 bits (125), Expect = 1.178e-6 Identity = 44/149 (29.53%), Postives = 74/149 (49.66%), Query Frame = 1 Query: 469 SETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 S I L F D E ++L NRI +A+++F+ ++ L L +N+L ++ F ++ ++LS N + + + F+ L K+ L+L + L RI+P GL L+ LFL N + IEE + L L ++L N L Sbjct: 336 SHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQL 484 HSP 3 Score: 52.373 bits (124), Expect = 1.625e-6 Identity = 54/221 (24.43%), Postives = 94/221 (42.53%), Query Frame = 1 Query: 334 SSLIVLMPQMFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNR------------------------LTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 +SL VL F+ + L LV+ + ++ L+ L +S + + +F P +++ L N I+ +A F + LDL +NR + +R F + H L+ L L NRI ++ + SF+ L +++VL L+ N L +K GL ++ + LS N + + E F L L ++LE + L R Sbjct: 218 NSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGR 438
BLAST of SMED30003270 vs. Ensembl Human
Match: IGFALS (insulin like growth factor binding protein acid labile subunit [Source:HGNC Symbol;Acc:HGNC:5468]) HSP 1 Score: 82.4185 bits (202), Expect = 4.530e-16 Identity = 58/186 (31.18%), Postives = 99/186 (53.23%), Query Frame = 1 Query: 355 PQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 P F+ +S L L +Q + ++E Q L +L LH+ ++ L+ G F+ P + LS+NR+S + D F+ + +L+LG N L V+ F SL+ L L+ NR+ ++ F L +++ L+L+ N L IK + L LQ L+L +N I + AF+ LK+L++++L N Sbjct: 91 PAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHN 276 HSP 2 Score: 52.7582 bits (125), Expect = 1.229e-6 Identity = 44/149 (29.53%), Postives = 74/149 (49.66%), Query Frame = 1 Query: 469 SETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 S I L F D E ++L NRI +A+++F+ ++ L L +N+L ++ F ++ ++LS N + + + F+ L K+ L+L + L RI+P GL L+ LFL N + IEE + L L ++L N L Sbjct: 298 SHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQL 446 HSP 3 Score: 51.9878 bits (123), Expect = 1.881e-6 Identity = 54/221 (24.43%), Postives = 94/221 (42.53%), Query Frame = 1 Query: 334 SSLIVLMPQMFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNR------------------------LTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 +SL VL F+ + L LV+ + ++ L+ L +S + + +F P +++ L N I+ +A F + LDL +NR + +R F + H L+ L L NRI ++ + SF+ L +++VL L+ N L +K GL ++ + LS N + + E F L L ++LE + L R Sbjct: 180 NSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGR 400
BLAST of SMED30003270 vs. Ensembl Human
Match: LRIG3 (leucine rich repeats and immunoglobulin like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991]) HSP 1 Score: 67.781 bits (164), Expect = 2.419e-11 Identity = 59/194 (30.41%), Postives = 101/194 (52.06%), Query Frame = 1 Query: 349 LMPQMFKLVSRLETLVV-QAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDF--SFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 LM F +S +E L + + I +L + L+ LH+S+ I +S + C + L+ N +S + D +F + + L +GNNR++ I F SL+ LDL N I+ IED +F L K++ L L N + I + GL++L++L LS N+I +++ +AF +K L+ ++L + LL Sbjct: 254 LMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLL 447
BLAST of SMED30003270 vs. Ensembl Human
Match: LRIG3 (leucine rich repeats and immunoglobulin like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991]) HSP 1 Score: 67.781 bits (164), Expect = 2.832e-11 Identity = 59/194 (30.41%), Postives = 101/194 (52.06%), Query Frame = 1 Query: 349 LMPQMFKLVSRLETLVV-QAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDF--SFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 LM F +S +E L + + I +L + L+ LH+S+ I +S + C + L+ N +S + D +F + + L +GNNR++ I F SL+ LDL N I+ IED +F L K++ L L N + I + GL++L++L LS N+I +++ +AF +K L+ ++L + LL Sbjct: 194 LMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLL 387
BLAST of SMED30003270 vs. Ensembl Human
Match: LRIG1 (leucine rich repeats and immunoglobulin like domains 1 [Source:HGNC Symbol;Acc:HGNC:17360]) HSP 1 Score: 67.3958 bits (163), Expect = 3.352e-11 Identity = 63/218 (28.90%), Postives = 100/218 (45.87%), Query Frame = 1 Query: 343 IVLMPQMFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCN------------------------RVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 + +P + S + +L +Q I+++E LK ++SL++L +S I + F P + + L+ NRI + FD + R+ LDL NR+ +I L F +SL+ L L RN I+++ D +F L KM VL+L N L+ + L+GL +L L LS NSI I + + L + L N L R Sbjct: 104 LTAVPSLGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTR 321
BLAST of SMED30003270 vs. Ensembl Celegans
Match: sma-10 (Leucine-rich repeats and immunoglobulin-like domains protein sma-10 [Source:UniProtKB/Swiss-Prot;Acc:Q965M2]) HSP 1 Score: 66.6254 bits (161), Expect = 1.991e-11 Identity = 46/167 (27.54%), Postives = 86/167 (51.50%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 I T+ ++ L +++ + +S I +L + S E++ L+SN I+ I F S N +V L L N +T + + F+ L++LDL+RN I + +F L ++ ++L N + R+ + + E L++L LS N ++ + E L SL+ ++L N Sbjct: 135 ISTVTSEELSYLAAVRSVDLSRNLISYLPKPTTSAKVNIEKLDLASNSITDIGTDHFSSFNTLVTLKLARNHITTLNQFSFSRLRKLESLDLTRNMIREVRFLAFNQLPSLQNVSLARNDVYRLDDGMFYACEGLKHLNLSTNRVQAVTEGWMFGLTSLEVLDLSYN 301
BLAST of SMED30003270 vs. Ensembl Celegans
Match: sma-10 (Leucine-rich repeats and immunoglobulin-like domains protein sma-10 [Source:UniProtKB/Swiss-Prot;Acc:Q965M2]) HSP 1 Score: 66.6254 bits (161), Expect = 1.991e-11 Identity = 46/167 (27.54%), Postives = 86/167 (51.50%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 I T+ ++ L +++ + +S I +L + S E++ L+SN I+ I F S N +V L L N +T + + F+ L++LDL+RN I + +F L ++ ++L N + R+ + + E L++L LS N ++ + E L SL+ ++L N Sbjct: 135 ISTVTSEELSYLAAVRSVDLSRNLISYLPKPTTSAKVNIEKLDLASNSITDIGTDHFSSFNTLVTLKLARNHITTLNQFSFSRLRKLESLDLTRNMIREVRFLAFNQLPSLQNVSLARNDVYRLDDGMFYACEGLKHLNLSTNRVQAVTEGWMFGLTSLEVLDLSYN 301
BLAST of SMED30003270 vs. Ensembl Celegans
Match: sma-10 (Leucine-rich repeats and immunoglobulin-like domains protein sma-10 [Source:UniProtKB/Swiss-Prot;Acc:Q965M2]) HSP 1 Score: 66.6254 bits (161), Expect = 2.194e-11 Identity = 46/167 (27.54%), Postives = 86/167 (51.50%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 I T+ ++ L +++ + +S I +L + S E++ L+SN I+ I F S N +V L L N +T + + F+ L++LDL+RN I + +F L ++ ++L N + R+ + + E L++L LS N ++ + E L SL+ ++L N Sbjct: 135 ISTVTSEELSYLAAVRSVDLSRNLISYLPKPTTSAKVNIEKLDLASNSITDIGTDHFSSFNTLVTLKLARNHITTLNQFSFSRLRKLESLDLTRNMIREVRFLAFNQLPSLQNVSLARNDVYRLDDGMFYACEGLKHLNLSTNRVQAVTEGWMFGLTSLEVLDLSYN 301
BLAST of SMED30003270 vs. Ensembl Celegans
Match: sma-10 (Leucine-rich repeats and immunoglobulin-like domains protein sma-10 [Source:UniProtKB/Swiss-Prot;Acc:Q965M2]) HSP 1 Score: 66.6254 bits (161), Expect = 2.194e-11 Identity = 46/167 (27.54%), Postives = 86/167 (51.50%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 I T+ ++ L +++ + +S I +L + S E++ L+SN I+ I F S N +V L L N +T + + F+ L++LDL+RN I + +F L ++ ++L N + R+ + + E L++L LS N ++ + E L SL+ ++L N Sbjct: 135 ISTVTSEELSYLAAVRSVDLSRNLISYLPKPTTSAKVNIEKLDLASNSITDIGTDHFSSFNTLVTLKLARNHITTLNQFSFSRLRKLESLDLTRNMIREVRFLAFNQLPSLQNVSLARNDVYRLDDGMFYACEGLKHLNLSTNRVQAVTEGWMFGLTSLEVLDLSYN 301
BLAST of SMED30003270 vs. Ensembl Celegans
Match: lron-2 (ELRR (Extracellular Leucine-Rich Repeat) ONly [Source:UniProtKB/TrEMBL;Acc:Q23580]) HSP 1 Score: 63.5438 bits (153), Expect = 1.500e-10 Identity = 44/160 (27.50%), Postives = 81/160 (50.62%), Query Frame = 1 Query: 232 VEWPILLMTVKKLRFNADLLAACQRISGL-----LITTESSLIVLMPQMFKLVSRLETLVV-QAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRN 693 +++P+L + L FN + Q G+ L T + P+MF+ +++L+TL + + PI I N + +L L +SE ++ + RG F P + I L+ NR+S + F+ N + ++DL NR+ ++ L F ++ +LD+S N Sbjct: 231 LDFPVL--SSLSLEFNGITVIPPQAFQGVPNLQFLYMTGNKFPSWAPEMFRYITQLKTLGIGETPISVIPNNAFMHIPNLIRLEMSEAAVDTIERGAFQRTPQIQAIVLNKNRLSQVRADFFEGLNDLYSIDLQGNRIDNVQPLGFANLPAISHLDISYN 388
BLAST of SMED30003270 vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330733) HSP 1 Score: 70.0922 bits (170), Expect = 2.842e-12 Identity = 55/213 (25.82%), Postives = 101/213 (47.42%), Query Frame = 1 Query: 292 AACQRI---SGLLITTESSLIVLMPQMFKLVSRLETLVVQAPIQTI--ENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 A C R+ +GL + + +P+ K+ + +E L +Q T+ E F + L++L +++ +I + R F D ER+RL++NR+ I + S ++ LD+ NN +T + R +F SL++L L N+IT +++ +FK GL L+ L L+ N++ ++ + F L L+ + L NP Sbjct: 71 ARCPRVCSCTGLNVDCSHRGLTSVPR--KISADVERLELQGNNLTVIYETDF-QRLTKLRMLQLTDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFK------------------------GLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPF 256
BLAST of SMED30003270 vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330731) HSP 1 Score: 70.0922 bits (170), Expect = 2.842e-12 Identity = 55/213 (25.82%), Postives = 101/213 (47.42%), Query Frame = 1 Query: 292 AACQRI---SGLLITTESSLIVLMPQMFKLVSRLETLVVQAPIQTI--ENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 A C R+ +GL + + +P+ K+ + +E L +Q T+ E F + L++L +++ +I + R F D ER+RL++NR+ I + S ++ LD+ NN +T + R +F SL++L L N+IT +++ +FK GL L+ L L+ N++ ++ + F L L+ + L NP Sbjct: 71 ARCPRVCSCTGLNVDCSHRGLTSVPR--KISADVERLELQGNNLTVIYETDF-QRLTKLRMLQLTDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFK------------------------GLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPF 256
BLAST of SMED30003270 vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330734) HSP 1 Score: 70.0922 bits (170), Expect = 3.102e-12 Identity = 55/213 (25.82%), Postives = 101/213 (47.42%), Query Frame = 1 Query: 292 AACQRI---SGLLITTESSLIVLMPQMFKLVSRLETLVVQAPIQTI--ENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 A C R+ +GL + + +P+ K+ + +E L +Q T+ E F + L++L +++ +I + R F D ER+RL++NR+ I + S ++ LD+ NN +T + R +F SL++L L N+IT +++ +FK GL L+ L L+ N++ ++ + F L L+ + L NP Sbjct: 71 ARCPRVCSCTGLNVDCSHRGLTSVPR--KISADVERLELQGNNLTVIYETDFQR-LTKLRMLQLTDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFK------------------------GLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPF 256
BLAST of SMED30003270 vs. Ensembl Fly
Match: CG7896 (gene:FBgn0039728 transcript:FBtr0085545) HSP 1 Score: 66.6254 bits (161), Expect = 3.025e-11 Identity = 52/193 (26.94%), Postives = 97/193 (50.26%), Query Frame = 1 Query: 340 LIVLMPQMFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 L L +FK + RL+ + + I+ I L LK +++++ +++ L G F + I LS+NRI I F + ++ LDL N+L+ + FN G ++ LD+S N+++ + SF+ +++ + N E++ L+ L+++ LS N ++TIEE F L L+ + + N L Sbjct: 534 LTPLTGALFKPLDRLQVIDLSGCNIRQISGDLLAGLQDLKHIYLNDNQLQELQDGSFVNLWNISSIDLSNNRIGSIRSGAFVNVMKLQKLDLHGNQLSAFKGEYFNTGTGIEELDISDNQLSYLFPSSFRIHPRLREIRAANNKFSFFPAELISTLQYLEHIDLSHNQLKTIEELDFARLPRLRVLLVANNQL 726 HSP 2 Score: 50.8322 bits (120), Expect = 2.443e-6 Identity = 43/170 (25.29%), Postives = 78/170 (45.88%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 I++I++ K ++ + ++ RI HL+ +F +++ LS N + + +L+L +N L + SL++LD+SRN IT I +F+ + +L+YL LS NS+ TIE+DA L SL+ + ++ N +L Sbjct: 244 IRSIDSLAFKGLQKIREIKLAGNRISHLNSDVFEKLQSLQKLDLSENFFGQFPTVALAAVPGLKHLNLSSNMLQQLDYTHMQVVRSLESLDISRNTITTITPGTFRE------------------------MGALKYLDLSLNSLRTIEDDALEGLDSLQTLIIKDNNIL 389
BLAST of SMED30003270 vs. Ensembl Fly
Match: CG32055 (gene:FBgn0052055 transcript:FBtr0076304) HSP 1 Score: 60.8474 bits (146), Expect = 1.452e-9 Identity = 62/197 (31.47%), Postives = 94/197 (47.72%), Query Frame = 1 Query: 328 TESSLIVLMPQMFKLVSRLETLVVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIF---NEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 +E+ + V+ P F+ + L L + Q EN L +L+ L IS + P E + L SN + + F + + L++ NN L I+R +F E L+ LD S N + ++D F LKK++ LNL N + RI P GL SLQ L L N I + +D F NL +L+ ++L KN Sbjct: 154 SENLIAVIEPNAFRHMKNLRFLDLTTNYQ--ENITLGENANLRFLSISNNNLRDFQWCHLRVLPKLEELHLHSNWLEHLDMGIFYALPNLRVLNVSNNNLFEIKRTLFMAPGEIAPLELLDYSSNIVKVLDDSVFCRLKKLRTLNLWLNQINRIHPRAFLGLSSLQTLHLQGNKISILPDDVFANLTALEKLDLSKN 348
BLAST of SMED30003270 vs. Ensembl Zebrafish
Match: lrig1 (leucine-rich repeats and immunoglobulin-like domains 1 [Source:ZFIN;Acc:ZDB-GENE-031113-23]) HSP 1 Score: 67.781 bits (164), Expect = 1.862e-11 Identity = 56/160 (35.00%), Postives = 90/160 (56.25%), Query Frame = 1 Query: 445 VSLKILHISETRIEHLSRGMFSDCPITERI-RLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 + +K LH+S +I HL G F + + +I RLS NR++ + K + ++ L+L NRL +I L F SL+ L L RN I+++ D +F L +M+VL+L+ N L + L+GLESL L+L+ NSI + + + L+ +NL N L + Sbjct: 130 LQIKDLHLSSNKIVHLEFGAFKNLAGSLQILRLSRNRLTHLPVKGLE-LPKLTQLELSRNRLRLIEGLTFQGLSSLEVLKLQRNNISKLTDGAFWGLARMRVLHLDYNSLREVNSGSLYGLESLLQLYLANNSISNFNPEGWGFCERLRELNLSYNNLTK 288 HSP 2 Score: 57.3806 bits (137), Expect = 2.681e-8 Identity = 58/218 (26.61%), Postives = 109/218 (50.00%), Query Frame = 1 Query: 307 ISGLLITTESSLIVLMPQ----------MFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDFS--FXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 I GL SSL VL Q F ++R+ L + ++ + + L SL L+++ I + + + C + LS N ++ +++ +F +++L LG+N ++ I F SL+ L+L N I+ IED S F L+ + L L N + + + GLE+L++L L +N+I +I+ +AF +K+L+Y++++ + L Sbjct: 193 IEGLTFQGLSSLEVLKLQRNNISKLTDGAFWGLARMRVLHLDYNSLREVNSGSLYGLESLLQLYLANNSISNFNPEGWGFCERLRELNLSYNNLTKLSEGSFAKLVNLISLRLGHNSISHITEGAFRGLSSLRTLELDHNDISGTIEDTSGAFTGLENLNKLTLFGNKIKSVAKKAFSGLEALEHLNLGENAIRSIQPEAFSKMKNLRYLHIQSDSFL 410
BLAST of SMED30003270 vs. Ensembl Zebrafish
Match: lrig1 (leucine-rich repeats and immunoglobulin-like domains 1 [Source:ZFIN;Acc:ZDB-GENE-031113-23]) HSP 1 Score: 67.781 bits (164), Expect = 1.943e-11 Identity = 56/160 (35.00%), Postives = 90/160 (56.25%), Query Frame = 1 Query: 445 VSLKILHISETRIEHLSRGMFSDCPITERI-RLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 + +K LH+S +I HL G F + + +I RLS NR++ + K + ++ L+L NRL +I L F SL+ L L RN I+++ D +F L +M+VL+L+ N L + L+GLESL L+L+ NSI + + + L+ +NL N L + Sbjct: 154 LQIKDLHLSSNKIVHLEFGAFKNLAGSLQILRLSRNRLTHLPVKGLE-LPKLTQLELSRNRLRLIEGLTFQGLSSLEVLKLQRNNISKLTDGAFWGLARMRVLHLDYNSLREVNSGSLYGLESLLQLYLANNSISNFNPEGWGFCERLRELNLSYNNLTK 312 HSP 2 Score: 57.3806 bits (137), Expect = 2.891e-8 Identity = 58/218 (26.61%), Postives = 109/218 (50.00%), Query Frame = 1 Query: 307 ISGLLITTESSLIVLMPQ----------MFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDFS--FXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 I GL SSL VL Q F ++R+ L + ++ + + L SL L+++ I + + + C + LS N ++ +++ +F +++L LG+N ++ I F SL+ L+L N I+ IED S F L+ + L L N + + + GLE+L++L L +N+I +I+ +AF +K+L+Y++++ + L Sbjct: 217 IEGLTFQGLSSLEVLKLQRNNISKLTDGAFWGLARMRVLHLDYNSLREVNSGSLYGLESLLQLYLANNSISNFNPEGWGFCERLRELNLSYNNLTKLSEGSFAKLVNLISLRLGHNSISHITEGAFRGLSSLRTLELDHNDISGTIEDTSGAFTGLENLNKLTLFGNKIKSVAKKAFSGLEALEHLNLGENAIRSIQPEAFSKMKNLRYLHIQSDSFL 434
BLAST of SMED30003270 vs. Ensembl Zebrafish
Match: lrig1 (leucine-rich repeats and immunoglobulin-like domains 1 [Source:ZFIN;Acc:ZDB-GENE-031113-23]) HSP 1 Score: 67.3958 bits (163), Expect = 2.067e-11 Identity = 56/160 (35.00%), Postives = 90/160 (56.25%), Query Frame = 1 Query: 445 VSLKILHISETRIEHLSRGMFSDCPITERI-RLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 + +K LH+S +I HL G F + + +I RLS NR++ + K + ++ L+L NRL +I L F SL+ L L RN I+++ D +F L +M+VL+L+ N L + L+GLESL L+L+ NSI + + + L+ +NL N L + Sbjct: 154 LQIKDLHLSSNKIVHLEFGAFKNLAGSLQILRLSRNRLTHLPVKGLE-LPKLTQLELSRNRLRLIEGLTFQGLSSLEVLKLQRNNISKLTDGAFWGLARMRVLHLDYNSLREVNSGSLYGLESLLQLYLANNSISNFNPEGWGFCERLRELNLSYNNLTK 312 HSP 2 Score: 53.1434 bits (126), Expect = 6.673e-7 Identity = 47/189 (24.87%), Postives = 94/189 (49.74%), Query Frame = 1 Query: 364 FKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXX---XXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 F+ +S LE L +Q I + + +++LH+ + ++ G ++ L++N IS + + C R+ L+L N LT + F + +L +L L N I+ I + +F+ L ++ L L+ + + GLE+L L L +N+I +I+ +AF +K+L+Y++++ + L Sbjct: 222 FQGLSSLEVLKLQRNNISKLTDGAFWGLARMRVLHLDYNSLREVNSGSLYGLESLLQLYLANNSISNFNPEGWGFCERLRELNLSYNNLTKLSEGSFAKLVNLISLRLGHNSISHITEGAFRGLSSLRTLELDHNDISGTIEDTSGAFTGLENLNKLNLGENAIRSIQPEAFSKMKNLRYLHIQSDSFL 410
BLAST of SMED30003270 vs. Ensembl Zebrafish
Match: lrrtm4l1 (leucine rich repeat transmembrane neuronal 4 like 1 [Source:ZFIN;Acc:ZDB-GENE-080327-15]) HSP 1 Score: 66.2402 bits (160), Expect = 3.736e-11 Identity = 55/187 (29.41%), Postives = 91/187 (48.66%), Query Frame = 1 Query: 358 QMFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 + F+ V RL+ L++ + I + N +L+ L +S +++ L G F + + L SN ++ I + F C + LDLG NRL V+ R F L L L N+ +RI F F L ++ L L N + + + + +LQ L +S N I+ ++ F L +L+ +NLE N L Sbjct: 117 RAFQGVRRLKELILSSNRISQLHNVTFHGVPNLRSLDLSYNKLQELQPGQFYGLRKLQNLHLRSNGLTAIPVRAFLECRSLEFLDLGYNRLRVLTRTAFLGLSRLMELHLEHNQFSRINFFLFPRLANLRALYLQWNRIRAVNQGLPWSWYTLQRLDISGNEIQVLDPVVFQCLPNLQVLNLESNKL 303
BLAST of SMED30003270 vs. Ensembl Zebrafish
Match: lrrn3a (leucine rich repeat neuronal 3a [Source:ZFIN;Acc:ZDB-GENE-061220-7]) HSP 1 Score: 65.855 bits (159), Expect = 5.130e-11 Identity = 64/263 (24.33%), Postives = 128/263 (48.67%), Query Frame = 1 Query: 133 CQKKCRCKHKEKSSKIEVAHCTVDEKDTFVSCNVEWPILLMTVKKLRFNADLLAACQRISGLLITTESSLIVLMPQMFKLVSRLETLVVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 C K C+C+ + S + + +E T V CN + L+T+ + R +D + +L++ +S+ + + LV+ E + + I ++ + ++ + L LH+ E + L + P + + ++ N +S+I+ + F N+++ L L +N+L IR F + L+ L + N I RI++ +FK L ++ L L L I L GL+ L+ + N + + A +++LK+++L KNP+ R Sbjct: 29 CLKLCKCEIRPWFSPLSM----YNEAPT-VDCN---DLGLLTLPE-RLPSD--------TQVLLSQANSIAKIDSPLDYLVNLTEVDLSRNNISSLSDIYIGHIPQLLSLHLEENWLSSLHDNFLAHFPNLQELYVNHNLLSLISAEAFQGLNKLLRLHLNSNQLRAIRSEWFQDLSQLEILMIGENPIARIQNMNFKPLINLRSLVLTRMNLTEIPDSALVGLDKLESVSFYDNMFPKVPQAALRQVRNLKFLDLNKNPIER 274
BLAST of SMED30003270 vs. Ensembl Xenopus
Match: IGFALS (insulin like growth factor binding protein acid labile subunit [Source:NCBI gene;Acc:100489984]) HSP 1 Score: 68.1662 bits (165), Expect = 1.272e-11 Identity = 52/189 (27.51%), Postives = 100/189 (52.91%), Query Frame = 1 Query: 346 VLMPQMFKLVSRLETLVV-QAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 +L+ + F+ +++LE L + +Q I +++ ++++S ++ L+ F + + S+ +S I + F + + L L NN + I F + H L LDL N++T + SF LK + L L++N ++ I PE+ ++ LQ+L LS N ++ + ED F+ L SL+Y++L+ N Sbjct: 321 ILLERTFEGLAQLELLSLNHNNVQEIRPGSFLGLLNVAVINLSGNCLKSLAEHCFKGLGKLHSLHMESSCLSHIKPQMFAGLSSIRRLFLQNNEIVAIENHSFTDLHGLLELDLRSNKLTHLTTRSFTGLKNLSYLLLSSNQILTISPEVFSPVQQLQWLDLSDNQLKALTEDIFLPLSSLRYLSLKNN 509 HSP 2 Score: 55.0694 bits (131), Expect = 2.166e-7 Identity = 49/193 (25.39%), Postives = 83/193 (43.01%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXX------------------------XXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 I T+ + +L+ L +S R+ L F P +RLS+N ++ + + F +V L+LG N++ ++ F L+ L L+ N + I SF L + L++ ++ L IKP++ GL S++ LFL N I IE +F +L L ++L N L Sbjct: 247 ISTVAPRAFSGMKNLRWLDLSHNRLTALYEDTFFGLPSLNVLRLSNNSLTSLRPRIFKDLQFLVELNLGQNKIKILLERTFEGLAQLELLSLNHNNVQEIRPGSFLGLLNVAVINLSGNCLKSLAEHCFKGLGKLHSLHMESSCLSHIKPQMFAGLSSIRRLFLQNNEIVAIENHSFTDLHGLLELDLRSNKL 439 HSP 3 Score: 51.9878 bits (123), Expect = 1.730e-6 Identity = 53/193 (27.46%), Postives = 95/193 (49.22%), Query Frame = 1 Query: 337 SLIVLMPQMF--KLVSRLETLVVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 +L+V++P M L++ E ++ + ++ + LK L +S ++ + +F+ T ++ L+ N IS +A + F + LDL +NRLT + F SL L LS N +T + FK+L+ + LNL N + + GL L+ L L+ N+++ I +F+ L ++ INL N Sbjct: 173 NLLVVLPDMVFHDLLNLRELVLAGNRLVYLQPSLFLSLGELKELDLSGNSLKGIKANVFTRQQKTHKLYLNHNHISTVAPRAFSGMKNLRWLDLSHNRLTALYEDTFFGLPSLNVLRLSNNSLTSLRPRIFKDLQFLVELNLGQNKIKILLERTFEGLAQLELLSLNHNNVQEIRPGSFLGLLNVAVINLSGN 365 HSP 4 Score: 49.6766 bits (117), Expect = 9.324e-6 Identity = 51/188 (27.13%), Postives = 84/188 (44.68%), Query Frame = 1 Query: 349 LMPQMFKLVSRLETLVVQAPIQT-IENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 L P F L +L + T IE+ +L L++ + L +F D + L+ NR+ + F S + LDL N L I+ +F L L+ N I+ + +F +K ++ L+L+ N L + + FGL SL L LS NS+ ++ F +L+ L +NL +N Sbjct: 130 LAPSTFTHTQNLVSLTLNNNFLTKIEDGLFSGLSNLWYLNLGWNLLVVLPDMVFHDLLNLRELVLAGNRLVYLQPSLFLSLGELKELDLSGNSLKGIKANVFTRQQKTHKLYLNHNHISTVAPRAFSGMKNLRWLDLSHNRLTALYEDTFFGLPSLNVLRLSNNSLTSLRPRIFKDLQFLVELNLGQN 317
BLAST of SMED30003270 vs. Ensembl Xenopus
Match: LRIG2 (leucine-rich repeats and immunoglobulin like domains 2 [Source:NCBI gene;Acc:100494845]) HSP 1 Score: 65.855 bits (159), Expect = 9.189e-11 Identity = 60/181 (33.15%), Postives = 94/181 (51.93%), Query Frame = 1 Query: 382 LETLVVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSS-NRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 LETL + + + T F + LK L++S RI L G F + + + + NRI+VI K+F + L+L NR+ ++ L F SL++L L RN I ++ D +F L M+ L L N + I L+GL SLQ L++S+N++ I DA+ + L ++L N L R Sbjct: 129 LETLDLSSNLLTEIKSFYFPRMPLKYLNLSNNRIATLEAGCFDNLSSSLLVLKLNRNRINVIQPKSF-KLPHLQYLELRRNRIKIVESLTFQGLDSLKSLKLQRNGIVKLMDGAFFGLDNMEQLELEYNNVTDINKGWLYGLRSLQQLYISQNAVHRISPDAWEFCQKLLDLDLSYNQLNR 308 HSP 2 Score: 58.151 bits (139), Expect = 2.422e-8 Identity = 51/197 (25.89%), Postives = 89/197 (45.18%), Query Frame = 1 Query: 334 SSLIVLMPQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 + ++ LM F + +E L ++ + I +L SL+ L+IS+ + +S + C + LS N+++ + D F + + ++LG+NR+ I +F +L LDL N I+ IED + E+ GL L L L N I++I AF L SL++++L N +L Sbjct: 232 NGIVKLMDGAFFGLDNMEQLELEYNNVTDINKGWLYGLRSLQQLYISQNAVHRISPDAWEFCQKLLDLDLSYNQLNRLDDFAFVGLSSLEKINLGDNRINHIAEGVFKGLANLLVLDLRNNEISWAIEDSN----------------------EVFAGLSRLHTLILQGNKIKSITMKAFTGLDSLQHLDLSNNAIL 406
BLAST of SMED30003270 vs. Ensembl Xenopus
Match: LRIG2 (leucine-rich repeats and immunoglobulin like domains 2 [Source:NCBI gene;Acc:100494845]) HSP 1 Score: 65.855 bits (159), Expect = 1.005e-10 Identity = 60/181 (33.15%), Postives = 94/181 (51.93%), Query Frame = 1 Query: 382 LETLVVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSS-NRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 LETL + + + T F + LK L++S RI L G F + + + + NRI+VI K+F + L+L NR+ ++ L F SL++L L RN I ++ D +F L M+ L L N + I L+GL SLQ L++S+N++ I DA+ + L ++L N L R Sbjct: 74 LETLDLSSNLLTEIKSFYFPRMPLKYLNLSNNRIATLEAGCFDNLSSSLLVLKLNRNRINVIQPKSF-KLPHLQYLELRRNRIKIVESLTFQGLDSLKSLKLQRNGIVKLMDGAFFGLDNMEQLELEYNNVTDINKGWLYGLRSLQQLYISQNAVHRISPDAWEFCQKLLDLDLSYNQLNR 253 HSP 2 Score: 58.151 bits (139), Expect = 2.528e-8 Identity = 51/197 (25.89%), Postives = 89/197 (45.18%), Query Frame = 1 Query: 334 SSLIVLMPQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 + ++ LM F + +E L ++ + I +L SL+ L+IS+ + +S + C + LS N+++ + D F + + ++LG+NR+ I +F +L LDL N I+ IED + E+ GL L L L N I++I AF L SL++++L N +L Sbjct: 177 NGIVKLMDGAFFGLDNMEQLELEYNNVTDINKGWLYGLRSLQQLYISQNAVHRISPDAWEFCQKLLDLDLSYNQLNRLDDFAFVGLSSLEKINLGDNRINHIAEGVFKGLANLLVLDLRNNEISWAIEDSN----------------------EVFAGLSRLHTLILQGNKIKSITMKAFTGLDSLQHLDLSNNAIL 351
BLAST of SMED30003270 vs. Ensembl Xenopus
Match: LRIG2 (leucine-rich repeats and immunoglobulin like domains 2 [Source:NCBI gene;Acc:100494845]) HSP 1 Score: 65.855 bits (159), Expect = 1.038e-10 Identity = 60/181 (33.15%), Postives = 94/181 (51.93%), Query Frame = 1 Query: 382 LETLVVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSS-NRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 LETL + + + T F + LK L++S RI L G F + + + + NRI+VI K+F + L+L NR+ ++ L F SL++L L RN I ++ D +F L M+ L L N + I L+GL SLQ L++S+N++ I DA+ + L ++L N L R Sbjct: 61 LETLDLSSNLLTEIKSFYFPRMPLKYLNLSNNRIATLEAGCFDNLSSSLLVLKLNRNRINVIQPKSF-KLPHLQYLELRRNRIKIVESLTFQGLDSLKSLKLQRNGIVKLMDGAFFGLDNMEQLELEYNNVTDINKGWLYGLRSLQQLYISQNAVHRISPDAWEFCQKLLDLDLSYNQLNR 240 HSP 2 Score: 58.151 bits (139), Expect = 2.414e-8 Identity = 51/197 (25.89%), Postives = 89/197 (45.18%), Query Frame = 1 Query: 334 SSLIVLMPQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 + ++ LM F + +E L ++ + I +L SL+ L+IS+ + +S + C + LS N+++ + D F + + ++LG+NR+ I +F +L LDL N I+ IED + E+ GL L L L N I++I AF L SL++++L N +L Sbjct: 164 NGIVKLMDGAFFGLDNMEQLELEYNNVTDINKGWLYGLRSLQQLYISQNAVHRISPDAWEFCQKLLDLDLSYNQLNRLDDFAFVGLSSLEKINLGDNRINHIAEGVFKGLANLLVLDLRNNEISWAIEDSN----------------------EVFAGLSRLHTLILQGNKIKSITMKAFTGLDSLQHLDLSNNAIL 338
BLAST of SMED30003270 vs. Ensembl Xenopus
Match: nprl2 (NPR2 like, GATOR1 complex subunit [Source:Xenbase;Acc:XB-GENE-854704]) HSP 1 Score: 64.6994 bits (156), Expect = 2.084e-10 Identity = 47/189 (24.87%), Postives = 94/189 (49.74%), Query Frame = 1 Query: 349 LMPQMFKLVSRLETLVV-QAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFG-LESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 L P +F + LE L++ + + ++ ++ LKN L L++S +I HL +FS +++ L N++ I F+ +++L L +N + + + F LQ+L LS+N++ ++ + + ++ P++LFG +E+L L+L + TI F NL +L+ + L +N Sbjct: 136 LHPNLFCCLQHLEELILNRNQLTSLPDELLKNLTKLISLNLSRNKISHLPMSIFSSLTKLKKLFLYDNQLVTITSSAFNKLGELLDLALYSNSIQFVAQDAFYHLPKLQSLKLSKNKL-QLLPYGLFLHLPQLSTLTLYDNPLKELPDVLFGKMENLTSLWLYNTHLTTIPNFVFCNLTNLQLLVLTRN 323 HSP 2 Score: 51.6026 bits (122), Expect = 2.509e-6 Identity = 52/169 (30.77%), Postives = 83/169 (49.11%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 + +I K+F LK L +++ +++ L GMF E++ L N +S + F + L L N+LT + + L +L+LSRN+I+ + F +L K+K L L N L+ I L L L L NSI+ + +DAF +L L+ + L KN L Sbjct: 85 LTSITRNAFKSFPHLKSLKLTDNKLKTLPAGMFDSLISLEQLFLDKNCLSSLHPNLFCCLQHLEELILNRNQLTSLPDELLKNLTKLISLNLSRNKISHLPMSIFSSLTKLKKLFLYDNQLVTITSSAFNKLGELLDLALYSNSIQFVAQDAFYHLPKLQSLKLSKNKL 253 HSP 3 Score: 50.447 bits (119), Expect = 5.921e-6 Identity = 36/150 (24.00%), Postives = 69/150 (46.00%), Query Frame = 1 Query: 460 LHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 +HI ET ++ F + P+T R+RL +N ++ I F S + +L L +N+L + +F+ SL+ L L +N ++ + P + L+ L+ L L++N + ++ ++ NL L +NL +N Sbjct: 54 IHIMETLATEITDKSFGNMPVTLRLRLEANHLTSITRNAFKSFPHLKSLKLTDNKLKTLPAGMFDSLISLEQLFLDKNCLSSLH------------------------PNLFCCLQHLEELILNRNQLTSLPDELLKNLTKLISLNLSRN 179
BLAST of SMED30003270 vs. Ensembl Mouse
Match: Lrig1 (leucine-rich repeats and immunoglobulin-like domains 1 [Source:MGI Symbol;Acc:MGI:107935]) HSP 1 Score: 70.0922 bits (170), Expect = 3.986e-12 Identity = 61/195 (31.28%), Postives = 93/195 (47.69%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCN------------------------RVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 I +++ LK+++SL++L +S I + F + + L+SNRIS++ FD + R+ LDL NR+ +I L F SL+ L L RN I+R+ D +F L KM VL+L N L+ + L+GL +L L LS NSI I+ D + + L + L N L R Sbjct: 129 ILSVDGSQLKSYLSLEVLDLSSNNITEIRSSCFPNGLRIRELNLASNRISILESGAFDGLSRSLLTLRLSKNRITQLPVKAFKLPRLTQLDLNRNRIRLIEGLTFQGLDSLEVLRLQRNNISRLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSISRIQRDGWSFCQKLHELILSFNNLTR 323 HSP 2 Score: 51.9878 bits (123), Expect = 1.557e-6 Identity = 51/162 (31.48%), Postives = 82/162 (50.62%), Query Frame = 1 Query: 433 LKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDFS--FXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLK--YINLE 903 L +L LH+S I + R +S C + LS N ++ + +++ + + L L +N ++ I F SL+ LDL N I+ IED S F L + L L N + + GLESL++L L +N+I +++ DAF +K+LK YI+ E Sbjct: 281 LYGLTALHQLHLSNNSISRIQRDGWSFCQKLHELILSFNNLTRLDEESLAELSSLSILRLSHNAISHIAEGAFKGLKSLRVLDLDHNEISGTIEDTSGAFTGLDNLSKLTLFGNKIKSVAKRAFSGLESLEHLNLGENAIRSVQFDAFAKMKNLKELYISSE 442
BLAST of SMED30003270 vs. Ensembl Mouse
Match: Lrig1 (leucine-rich repeats and immunoglobulin-like domains 1 [Source:MGI Symbol;Acc:MGI:107935]) HSP 1 Score: 70.0922 bits (170), Expect = 3.986e-12 Identity = 61/195 (31.28%), Postives = 93/195 (47.69%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCN------------------------RVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 I +++ LK+++SL++L +S I + F + + L+SNRIS++ FD + R+ LDL NR+ +I L F SL+ L L RN I+R+ D +F L KM VL+L N L+ + L+GL +L L LS NSI I+ D + + L + L N L R Sbjct: 129 ILSVDGSQLKSYLSLEVLDLSSNNITEIRSSCFPNGLRIRELNLASNRISILESGAFDGLSRSLLTLRLSKNRITQLPVKAFKLPRLTQLDLNRNRIRLIEGLTFQGLDSLEVLRLQRNNISRLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSISRIQRDGWSFCQKLHELILSFNNLTR 323 HSP 2 Score: 51.9878 bits (123), Expect = 1.557e-6 Identity = 51/162 (31.48%), Postives = 82/162 (50.62%), Query Frame = 1 Query: 433 LKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDFS--FXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLK--YINLE 903 L +L LH+S I + R +S C + LS N ++ + +++ + + L L +N ++ I F SL+ LDL N I+ IED S F L + L L N + + GLESL++L L +N+I +++ DAF +K+LK YI+ E Sbjct: 281 LYGLTALHQLHLSNNSISRIQRDGWSFCQKLHELILSFNNLTRLDEESLAELSSLSILRLSHNAISHIAEGAFKGLKSLRVLDLDHNEISGTIEDTSGAFTGLDNLSKLTLFGNKIKSVAKRAFSGLESLEHLNLGENAIRSVQFDAFAKMKNLKELYISSE 442
BLAST of SMED30003270 vs. Ensembl Mouse
Match: Lrig1 (leucine-rich repeats and immunoglobulin-like domains 1 [Source:MGI Symbol;Acc:MGI:107935]) HSP 1 Score: 70.0922 bits (170), Expect = 3.986e-12 Identity = 61/195 (31.28%), Postives = 93/195 (47.69%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCN------------------------RVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 I +++ LK+++SL++L +S I + F + + L+SNRIS++ FD + R+ LDL NR+ +I L F SL+ L L RN I+R+ D +F L KM VL+L N L+ + L+GL +L L LS NSI I+ D + + L + L N L R Sbjct: 129 ILSVDGSQLKSYLSLEVLDLSSNNITEIRSSCFPNGLRIRELNLASNRISILESGAFDGLSRSLLTLRLSKNRITQLPVKAFKLPRLTQLDLNRNRIRLIEGLTFQGLDSLEVLRLQRNNISRLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSISRIQRDGWSFCQKLHELILSFNNLTR 323 HSP 2 Score: 51.9878 bits (123), Expect = 1.557e-6 Identity = 51/162 (31.48%), Postives = 82/162 (50.62%), Query Frame = 1 Query: 433 LKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDFS--FXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLK--YINLE 903 L +L LH+S I + R +S C + LS N ++ + +++ + + L L +N ++ I F SL+ LDL N I+ IED S F L + L L N + + GLESL++L L +N+I +++ DAF +K+LK YI+ E Sbjct: 281 LYGLTALHQLHLSNNSISRIQRDGWSFCQKLHELILSFNNLTRLDEESLAELSSLSILRLSHNAISHIAEGAFKGLKSLRVLDLDHNEISGTIEDTSGAFTGLDNLSKLTLFGNKIKSVAKRAFSGLESLEHLNLGENAIRSVQFDAFAKMKNLKELYISSE 442
BLAST of SMED30003270 vs. Ensembl Mouse
Match: Lrig3 (leucine-rich repeats and immunoglobulin-like domains 3 [Source:MGI Symbol;Acc:MGI:2443955]) HSP 1 Score: 67.3958 bits (163), Expect = 2.587e-11 Identity = 58/194 (29.90%), Postives = 101/194 (52.06%), Query Frame = 1 Query: 349 LMPQMFKLVSRLETLVV-QAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDFS--FXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 LM F +S +E L + + I +L + L+ LH+S+ I +S + C + L+ N +S + D +F + + L +GNN+++ I F SL+ LDL N I+ IED S F L +++ L L N + I + GL++L++L LS N+I +++ +AF +K L+ ++L + LL Sbjct: 254 LMDGAFWGLSNMEVLQLDHNNLTEITKGWLYGLLMLRELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNALHIGNNKVSYIADCAFRGLTSLKTLDLRNNEISWTIEDMSGAFSGLDRLRQLILQGNRIRSITKKAFAGLDTLEHLDLSGNAIMSLQSNAFSQMKKLQQLHLNTSSLL 447
BLAST of SMED30003270 vs. Ensembl Mouse
Match: Slit1 (slit guidance ligand 1 [Source:MGI Symbol;Acc:MGI:1315203]) HSP 1 Score: 67.3958 bits (163), Expect = 2.715e-11 Identity = 45/156 (28.85%), Postives = 72/156 (46.15%), Query Frame = 1 Query: 451 LKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 L++L + E +I + RG F D ER+RL+ N++ V+ + F + + LDL N L + R F L+NL L +NRI+ IE+ +F+ L L+ L L+ N+I TI +F ++ L+ L N L Sbjct: 87 LRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLQVLPELLFQNNQALSRLDLSENFLQAVPRKAFRGATDLKNLQLDKNRISCIEEGAFR------------------------ALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLF 218 HSP 2 Score: 58.151 bits (139), Expect = 1.824e-8 Identity = 44/139 (31.65%), Postives = 62/139 (44.60%), Query Frame = 1 Query: 499 GMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 G+F ++I LS+N++S I D TF+ V L L N+L IR +F L+ L L NRI+ I + SF GL +++ L L N I TI AF L++L +NL NP Sbjct: 559 GLFKKLSHLKKINLSNNKVSEIEDGTFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFT------------------------GLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANPF 673
BLAST of SMED30003270 vs. UniProt/SwissProt
Match: sp|P35858|ALS_HUMAN (Insulin-like growth factor-binding protein complex acid labile subunit OS=Homo sapiens OX=9606 GN=IGFALS PE=1 SV=1) HSP 1 Score: 82.4185 bits (202), Expect = 2.176e-15 Identity = 58/186 (31.18%), Postives = 99/186 (53.23%), Query Frame = 1 Query: 355 PQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 P F+ +S L L +Q + ++E Q L +L LH+ ++ L+ G F+ P + LS+NR+S + D F+ + +L+LG N L V+ F SL+ L L+ NR+ ++ F L +++ L+L+ N L IK + L LQ L+L +N I + AF+ LK+L++++L N Sbjct: 91 PAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHN 276 HSP 2 Score: 52.7582 bits (125), Expect = 5.902e-6 Identity = 44/149 (29.53%), Postives = 74/149 (49.66%), Query Frame = 1 Query: 469 SETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 S I L F D E ++L NRI +A+++F+ ++ L L +N+L ++ F ++ ++LS N + + + F+ L K+ L+L + L RI+P GL L+ LFL N + IEE + L L ++L N L Sbjct: 298 SHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQL 446 HSP 3 Score: 51.9878 bits (123), Expect = 9.035e-6 Identity = 54/221 (24.43%), Postives = 94/221 (42.53%), Query Frame = 1 Query: 334 SSLIVLMPQMFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNR------------------------LTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 +SL VL F+ + L LV+ + ++ L+ L +S + + +F P +++ L N I+ +A F + LDL +NR + +R F + H L+ L L NRI ++ + SF+ L +++VL L+ N L +K GL ++ + LS N + + E F L L ++LE + L R Sbjct: 180 NSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGR 400
BLAST of SMED30003270 vs. UniProt/SwissProt
Match: sp|O02833|ALS_PAPHA (Insulin-like growth factor-binding protein complex acid labile subunit OS=Papio hamadryas OX=9557 GN=IGFALS PE=2 SV=1) HSP 1 Score: 79.7221 bits (195), Expect = 1.414e-14 Identity = 57/186 (30.65%), Postives = 98/186 (52.69%), Query Frame = 1 Query: 355 PQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 P F+ +S L L +Q + ++E Q L +L LH+ ++ L+ G F+ P + LS+NR+S + D F+ + +L+LG N L V+ F L+ L L+ NR+ ++ F L +++ L+L+ N L IK + L LQ L+L +N I + AF+ LK+L++++L N Sbjct: 91 PAAFRNLSSLAFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLAVGTFAYTPALALLGLSNNRLSRLEDGLFEGLGNLWDLNLGWNSLAVLPDAAFRGLGGLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFAQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHN 276 HSP 2 Score: 52.373 bits (124), Expect = 6.902e-6 Identity = 54/221 (24.43%), Postives = 95/221 (42.99%), Query Frame = 1 Query: 334 SSLIVLMPQMFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNR------------------------LTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 +SL VL F+ + L LV+ + ++ L+ L +S + + +F+ P +++ L N I+ +A F + LDL +NR + +R F + H L+ L L NRI ++ + SF+ L +++VL L+ N L +K GL ++ + LS N + + E F L L ++LE + L R Sbjct: 180 NSLAVLPDAAFRGLGGLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFAQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFEDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKVGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGR 400 HSP 3 Score: 52.373 bits (124), Expect = 7.931e-6 Identity = 44/149 (29.53%), Postives = 74/149 (49.66%), Query Frame = 1 Query: 469 SETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 S I L F D E ++L NRI +A+++F+ ++ L L +N+L ++ F ++ ++LS N + + + F+ L K+ L+L + L RI+P GL L+ LFL N + IEE + L L ++L N L Sbjct: 298 SHNAIASLRPRTFEDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKVGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFAGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQL 446
BLAST of SMED30003270 vs. UniProt/SwissProt
Match: sp|P70193|LRIG1_MOUSE (Leucine-rich repeats and immunoglobulin-like domains protein 1 OS=Mus musculus OX=10090 GN=Lrig1 PE=1 SV=2) HSP 1 Score: 70.0922 bits (170), Expect = 2.788e-11 Identity = 61/195 (31.28%), Postives = 93/195 (47.69%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCN------------------------RVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 I +++ LK+++SL++L +S I + F + + L+SNRIS++ FD + R+ LDL NR+ +I L F SL+ L L RN I+R+ D +F L KM VL+L N L+ + L+GL +L L LS NSI I+ D + + L + L N L R Sbjct: 129 ILSVDGSQLKSYLSLEVLDLSSNNITEIRSSCFPNGLRIRELNLASNRISILESGAFDGLSRSLLTLRLSKNRITQLPVKAFKLPRLTQLDLNRNRIRLIEGLTFQGLDSLEVLRLQRNNISRLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSISRIQRDGWSFCQKLHELILSFNNLTR 323
BLAST of SMED30003270 vs. UniProt/SwissProt
Match: sp|P24014|SLIT_DROME (Protein slit OS=Drosophila melanogaster OX=7227 GN=sli PE=1 SV=2) HSP 1 Score: 70.0922 bits (170), Expect = 2.849e-11 Identity = 55/213 (25.82%), Postives = 101/213 (47.42%), Query Frame = 1 Query: 292 AACQRI---SGLLITTESSLIVLMPQMFKLVSRLETLVVQAPIQTI--ENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 A C R+ +GL + + +P+ K+ + +E L +Q T+ E F + L++L +++ +I + R F D ER+RL++NR+ I + S ++ LD+ NN +T + R +F SL++L L N+IT +++ +FK GL L+ L L+ N++ ++ + F L L+ + L NP Sbjct: 71 ARCPRVCSCTGLNVDCSHRGLTSVPR--KISADVERLELQGNNLTVIYETDF-QRLTKLRMLQLTDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFK------------------------GLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPF 256
BLAST of SMED30003270 vs. UniProt/SwissProt
Match: sp|P35859|ALS_RAT (Insulin-like growth factor-binding protein complex acid labile subunit OS=Rattus norvegicus OX=10116 GN=Igfals PE=1 SV=1) HSP 1 Score: 68.1662 bits (165), Expect = 7.181e-11 Identity = 53/183 (28.96%), Postives = 101/183 (55.19%), Query Frame = 1 Query: 364 FKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 F+ +S L+ L +Q ++++E Q L +L LH+ R+ +L+ G+F+ P + LSSN + + + F + + +L+LG N L V+ +F +L L L+ N++T ++ F L +++ L+L+ N L +K + L LQ L+L +N I + AF+ +K+L++++L N Sbjct: 94 FQNLSSLDFLNLQGSWLRSLEPQALLGLQNLYYLHLERNRLRNLAVGLFTHTPSLASLSLSSNLLGRLEEGLFQGLSHLWDLNLGWNSLVVLPDTVFQGLGNLHELVLAGNKLTYLQPALFCGLGELRELDLSRNALRSVKANVFVHLPRLQKLYLDRNLITAVAPGAFLGMKALRWLDLSHN 276 HSP 2 Score: 58.9214 bits (141), Expect = 5.544e-8 Identity = 47/166 (28.31%), Postives = 84/166 (50.60%), Query Frame = 1 Query: 418 IENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 +E+ F + L +L ++ I L F D E ++L NRI + ++TF+ ++ L L +N++T +R F+ ++ ++LS N + + + F+ L K+ L+L + L ++ GL L+ LFL NSI +IEE + L L ++L N L Sbjct: 282 MEDTF-PGLLGLHVLRLAHNAIASLRPRTFKDLHFLEELQLGHNRIRQLGERTFEGLGQLEVLTLNDNQITEVRVGAFSGLFNVAVMNLSGNCLRSLPERVFQGLDKLHSLHLEHSCLGHVRLHTFAGLSGLRRLFLRDNSISSIEEQSLAGLSELLELDLTTNRL 446 HSP 3 Score: 54.6842 bits (130), Expect = 1.254e-6 Identity = 41/169 (24.26%), Postives = 76/169 (44.97%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 ++++ + + L LH+ + + H+ F+ R+ L N IS I +++ + ++ LDL NRLT + R +F L+ L LS N++T + E+L L+ +L +S N +ET+ E F +L ++Y++L N L Sbjct: 374 LRSLPERVFQGLDKLHSLHLEHSCLGHVRLHTFAGLSGLRRLFLRDNSISSIEEQSLAGLSELLELDLTTNRLTHLPRQLFQGLGHLEYLLLSYNQLT------------------------TLSAEVLGPLQRAFWLDISHNHLETLAEGLFSSLGRVRYLSLRNNSL 518
BLAST of SMED30003270 vs. TrEMBL
Match: A0A3Q1FV13 (Insulin-like growth factor binding protein, acid labile subunit OS=Acanthochromis polyacanthus OX=80966 PE=4 SV=1) HSP 1 Score: 91.2781 bits (225), Expect = 7.048e-16 Identity = 75/263 (28.52%), Postives = 131/263 (49.81%), Query Frame = 1 Query: 130 PCQKKCRCKHKEKSSKIEVAHCTVDEKDTFVSCNVEWPILLMTVKKLRFNADLLAACQRISGLLITTESSLIVLMPQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 PC K C C H + SS++ + +C+ F + P + L + +L + +S F+ +S L+ L +Q+ + TI+ Q K SL +H+ R+ L +F + P + L +N++S I ++ F + + L+LG N LTV+ + F++ L+ L L+ NR+ ++ F+NL ++K L+L N L IK + L LQ L+L++N I T+ AFV +KSL++++L N L Sbjct: 34 PCSKGCTCLHDDYSSELNM-YCSARN---FTQVPTDMPT---STHSLWLDGNLFTSLPAVS-----------------FRDLSNLDFLNLQSGQLMTIDAQAFKGLRSLAHIHLERNRLRGLPGAIFQNTPNLASLSLHNNQLSRIEERLFAGLSHMWLLNLGWNSLTVLPEMAFHDLQGLRELILAGNRLAYLQPQLFQNLVELKELDLTGNSLKNIKANVFVKLTKLQKLYLAQNQIVTVVPRAFVGMKSLRWLDLTNNKL 272
BLAST of SMED30003270 vs. TrEMBL
Match: A0A3B3YX16 (Insulin-like growth factor binding protein, acid labile subunit OS=Poecilia mexicana OX=48701 PE=4 SV=1) HSP 1 Score: 88.1965 bits (217), Expect = 8.196e-15 Identity = 74/263 (28.14%), Postives = 132/263 (50.19%), Query Frame = 1 Query: 130 PCQKKCRCKHKEKSSKIEVAHCTVDEKDTFVSCNVEWPILLMTVKKLRFNADLLAACQRISGLLITTESSLIVLMPQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 PC K C C H + S+++ + +C+ T V ++ + + F L AAC F+ +S L+ L +Q+ + T+++Q + SL LHI R+ L +F + P + L +N IS I ++ F + + L+LG N LTV+ +F++ L+ L+L+ NR+ ++ F+NL ++K L+L N + IK + L LQ L+L++N I ++ AFV +KSL+++++ N L Sbjct: 34 PCAKGCNCMHDDYSAEL-IVYCSA-RNLTQVPADIPPSTHYLWLDGNLF-VSLPAAC---------------------FRDLSNLDFLNLQSGQLLTLDHQTFRGLRSLAHLHIERNRLRGLPGSIFQNTPNLASLSLHNNHISRIDERLFAGLSHMWFLNLGWNSLTVLPETVFHDLQGLRELNLAGNRLAYLQPALFQNLGELKELDLTGNYIKVIKANVFVKLHKLQKLYLAQNQIGSVVPRAFVGMKSLRWLDMRNNKL 272
BLAST of SMED30003270 vs. TrEMBL
Match: A0A087YST5 (Insulin-like growth factor binding protein, acid labile subunit OS=Poecilia formosa OX=48698 PE=4 SV=2) HSP 1 Score: 88.1965 bits (217), Expect = 9.207e-15 Identity = 74/263 (28.14%), Postives = 132/263 (50.19%), Query Frame = 1 Query: 130 PCQKKCRCKHKEKSSKIEVAHCTVDEKDTFVSCNVEWPILLMTVKKLRFNADLLAACQRISGLLITTESSLIVLMPQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 PC K C C H + S+++ + +C+ T V ++ + + F L AAC F+ +S L+ L +Q+ + T+++Q + SL LHI R+ L +F + P + L +N IS I ++ F + + L+LG N LTV+ +F++ L+ L+L+ NR+ ++ F+NL ++K L+L N + IK + L LQ L+L++N I ++ AFV +KSL+++++ N L Sbjct: 34 PCAKGCNCMHDDYSTEL-IVYCSA-RNLTQVPADIPPSTHYLWLDGNLF-VSLPAAC---------------------FRDLSNLDFLNLQSGQLLTLDHQTFRGLRSLAHLHIERNRLRGLPGSIFQNTPNLASLSLHNNHISRIDERLFAGLSHMWFLNLGWNSLTVLPETVFHDLQGLRELNLAGNRLAYLQPALFQNLGELKELDLTGNYIKVIKANVFVKLHKLQKLYLAQNQIGSVVPRAFVGMKSLRWLDMRNNKL 272
BLAST of SMED30003270 vs. TrEMBL
Match: A0A3B3TLZ0 (Insulin-like growth factor binding protein, acid labile subunit OS=Poecilia latipinna OX=48699 PE=4 SV=1) HSP 1 Score: 88.1965 bits (217), Expect = 9.289e-15 Identity = 74/263 (28.14%), Postives = 132/263 (50.19%), Query Frame = 1 Query: 130 PCQKKCRCKHKEKSSKIEVAHCTVDEKDTFVSCNVEWPILLMTVKKLRFNADLLAACQRISGLLITTESSLIVLMPQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 PC K C C H + S+++ + +C+ T V ++ + + F L AAC F+ +S L+ L +Q+ + T+++Q + SL LHI R+ L +F + P + L +N IS I ++ F + + L+LG N LTV+ +F++ L+ L+L+ NR+ ++ F+NL ++K L+L N + IK + L LQ L+L++N I ++ AFV +KSL+++++ N L Sbjct: 34 PCAKGCNCMHDDYSTEL-IVYCSA-RNLTQVPADIPPSTHYLWLDGNLF-VSLPAAC---------------------FRDLSNLDFLNLQSGQLLTLDHQTFRGLRSLAHLHIERNRLRGLPGSIFQNTPNLASLSLHNNHISRIDERLFAGLSHMWFLNLGWNSLTVLPETVFHDLQGLRELNLAGNRLAYLQPALFQNLGELKELDLTGNYIKVIKANVFVKLHKLQKLYLAQNQIGSVVPRAFVGMKSLRWLDMRNNKL 272
BLAST of SMED30003270 vs. TrEMBL
Match: A0A1S3R9S0 (insulin-like growth factor-binding protein complex acid labile subunit OS=Salmo salar OX=8030 GN=LOC106601095 PE=4 SV=1) HSP 1 Score: 87.4261 bits (215), Expect = 1.561e-14 Identity = 79/268 (29.48%), Postives = 128/268 (47.76%), Query Frame = 1 Query: 130 PCQKKCRCKHKEKSSKIEVAHC-----TVDEKDTFVSCNVEWPILLMTVKKLRFNADLLAACQRISGLLITTESSLIVLMPQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 PC K C C H + S ++ V +C T D VS W + G L TT L FK +S L+ L +Q+ + ++++Q + SL +H+ RI L +F + P + L +N++S I +K F + + L+LG N L V+ F++ H L+ L L+ NR+ ++ F+ L ++K L+L N L IK + L LQ L+L++N I T+ AFV +KSL++++L N L Sbjct: 34 PCSKGCTCLHDDYSLELNV-YCSARNYTQAPSDVPVSTRSLW----------------------LDGNLFTT------LPATAFKDLSNLDFLNLQSGQLVSLDSQVFRGLKSLAHIHLERNRIRSLPGTIFQNTPNLASLSLHNNQLSRIEEKMFAGLSHMWLLNLGWNSLAVLPETGFHDLHGLRELVLAGNRLAYLQPQLFQGLTELKELDLTGNYLKVIKANVFMKLPKLQKLYLAQNQIVTVVPRAFVGMKSLRWLDLTNNKL 272 HSP 2 Score: 65.4698 bits (158), Expect = 1.512e-7 Identity = 56/200 (28.00%), Postives = 96/200 (48.00%), Query Frame = 1 Query: 319 LITTESSLIVLMPQMFKLVSRLETL-VVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 L ++ ++ ++P+ F + L L + + + ++ SL +L +S I L F D E +RLS NRI +AD+ F+ + L+L +N++ R F L ++LS + + D FK L K+ L+L+ L R+ + GL L+ LFL N+I +E +FV L L+ ++L N L Sbjct: 241 LYLAQNQIVTVVPRAFVGMKSLRWLDLTNNKLSALHDETFLGLHSLHVLRLSNNSISGLRPRTFRDLQYLEELRLSYNRIQALADRIFEGLGHLEVLELEHNQVQEARMGTFMGLSHLAVINLSGSCFRSLPDQVFKGLSKLHSLHLDKGCLTRVTTQAFIGLSGLRRLFLQNNNISVVERQSFVELLGLQQLDLRFNKL 440
BLAST of SMED30003270 vs. Ensembl Cavefish
Match: igfals (insulin like growth factor binding protein acid labile subunit [Source:NCBI gene;Acc:103036545]) HSP 1 Score: 83.9593 bits (206), Expect = 8.090e-17 Identity = 74/265 (27.92%), Postives = 134/265 (50.57%), Query Frame = 1 Query: 130 PCQKKCRCKHKEKSSKIEVAHCTVDEKDTFVSCNVEW--PILLMTVKKLRFNADLLAACQRISGLLITTESSLIVLMPQMFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 PC K+C C + +S++ V +C+ S N+ P L + + L + +L A L FK ++ L+ L +Q+ + ++++Q K +L LH+ + L +F + P + L +N++S I ++ F + + L+LG N L+V+ F++ H L+ L LS NR+ ++ F+ L ++K L+L+ N L IK + L LQ L+L++N I T+ AFV +KSL++++L +N L Sbjct: 32 PCSKRCTCLLDDYTSELSV-YCS--------SRNLTQAPPDLPASTRSLWLDGNLFA-----------------TLPADSFKNLTNLDFLNLQSGQLTSLDSQVFKRLHNLAHLHLERNSLRILPAAIFQNTPNLATLNLHNNQLSRIEERLFAGLSHMWLLNLGWNSLSVLPETGFHDLHGLRELVLSGNRLAYLQPQLFQGLTELKELDLSGNQLRVIKANVFLKLPKLQKLYLAQNQITTVAPRAFVGMKSLRWLDLSRNRL 270 HSP 2 Score: 56.9954 bits (136), Expect = 3.135e-8 Identity = 51/190 (26.84%), Postives = 90/190 (47.37%), Query Frame = 1 Query: 334 SSLIVLMPQMFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINL 900 +SL VL F + L LV+ + ++ Q + LK L +S ++ + +F P +++ L+ N+I+ +A + F + LDL NRLT++ F HSL L LS N I + +F++L+ ++ L++ N + + + GL L+ L L N ++ F+ L L I L Sbjct: 172 NSLSVLPETGFHDLHGLRELVLSGNRLAYLQPQLFQGLTELKELDLSGNQLRVIKANVFLKLPKLQKLYLAQNQITTVAPRAFVGMKSLRWLDLSRNRLTILHDETFLGLHSLHVLRLSNNSINSLRPGTFRDLQYLEELDMCHNQIRALGERVFEGLGHLEVLSLEYNKLQDARSGTFMGLSHLAVIKL 361 HSP 3 Score: 52.373 bits (124), Expect = 8.933e-7 Identity = 47/197 (23.86%), Postives = 94/197 (47.72%), Query Frame = 1 Query: 328 TESSLIVLMPQMFKLVSRLETL-VVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 + +S+ L P F+ + LE L + I+ + + + L++L + +++ G F I+L+ + + D+ F +++ ++ L LT + F SL+ L L N I+ ++ SF L+ ++ L++ N L + +GL++L+YL LSKN I + + L+ L +++L N L Sbjct: 290 SNNSINSLRPGTFRDLQYLEELDMCHNQIRALGERVFEGLGHLEVLSLEYNKLQDARSGTFMGLSHLAVIKLTGSCFRSLPDQVFKGLSKLHSMHLDKGCLTKVSTQGFIGLASLRRLFLQHNNISAVDRQSFVELQGLQQLDMRFNNLASLTSHTFYGLKALEYLLLSKNLIRHFPSEVLLPLQQLSWLDLSGNKL 486
BLAST of SMED30003270 vs. Ensembl Cavefish
Match: lrrn3a (leucine rich repeat neuronal 3 [Source:NCBI gene;Acc:103039721]) HSP 1 Score: 73.9442 bits (180), Expect = 1.341e-13 Identity = 56/184 (30.43%), Postives = 92/184 (50.00%), Query Frame = 1 Query: 370 LVSRLETLVVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 LV+ E V Q + + + + + L LH+ E RI L FS P + + ++ N +S+I+D F ++ L L +N+L VIR FN + L+ L + N I +I+D +FK L + L L L I L GL +L+ + N + + A ++SLK+++L KNP+ R Sbjct: 91 LVNLTEVDVSQNNVTRLSDLNVGHLPQLLSLHMEENRISTLHDNSFSHLPNLQELYVNHNLLSLISDGAFQGLGNLLRLHLNSNQLRVIRPEWFNALNQLEILMIGENPIAQIQDMNFKPLSNLLSLVLARMNLTEIPDNALVGLNNLESISFYDNKFAKVPQSALRKVQSLKFLDLNKNPIER 274
BLAST of SMED30003270 vs. Ensembl Cavefish
Match: ENSAMXT00000025596.2 (pep primary_assembly:Astyanax_mexicanus-2.0:1:16543202:16552825:-1 gene:ENSAMXG00000024870.2 transcript:ENSAMXT00000025596.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 73.1738 bits (178), Expect = 2.841e-13 Identity = 56/197 (28.43%), Postives = 93/197 (47.21%), Query Frame = 1 Query: 328 TESSLIVLMPQMFKLVSRLETL-VVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 + S L VL P +F+ V +L+ L + + ++ N L+ L + + +I + +F + + + SN IS + TF + R+V++DL NN+LT I +F L +LDLS+N +T + +FK + L LFL KN+I ++ E+AF L LK ++L NPL Sbjct: 323 SSSKLQVLPPSVFQDVGKLKHLCLFDIALTSLPQGLFNNLTLLQELQLDKNKIHIIPPDLFHPLSKLKHLHMDSNLISELNSSTFRTLRRLVHIDLSNNQLTNISSGLFKGTRKLAHLDLSKNMLTAVPTEAFKE------------------------IPRLNRLFLQKNAISSVPENAFSGLAGLKKLDLSNNPL 495 HSP 2 Score: 72.7886 bits (177), Expect = 3.962e-13 Identity = 52/169 (30.77%), Postives = 81/169 (47.93%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 I+ + +FL+ +LKIL +S I LS G F E I L+ N I +I F++C + L L NN L+ + F H L++LDLS+NR++ + ++ P +L L+L +N I + E+AF +L SL+ +NL NPL Sbjct: 159 IKILPQKFLQGLTNLKILVLSLNEILSLSYGAFEGGSDLEEIHLNKNHIKIIEKGVFENCTYLNKLVLSNNNLSSVEEGTFLGLHGLRHLDLSKNRLSTVP-----------------TGTLKDTP-------NLTSLYLHQNGITRVPENAFYSLSSLQMLNLNNNPL 303
BLAST of SMED30003270 vs. Ensembl Cavefish
Match: lrig3 (leucine rich repeats and immunoglobulin like domains 3 [Source:NCBI gene;Acc:103037077]) HSP 1 Score: 71.2478 bits (173), Expect = 1.244e-12 Identity = 58/158 (36.71%), Postives = 88/158 (55.70%), Query Frame = 1 Query: 451 LKILHISETRIEHLSRGMFSDCPITERI-RLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 LK L+++ RI L G ++ T + RL+ NR++ I KTF N + +LDL NR+ I L F+ H L++L + RN ITR+ D +F L M++L L N L + L+GL +LQ L L+ N+I I+ DA+ + L ++L N L R Sbjct: 154 LKNLYLNNNRISVLEHGCLNNLSSTLLVLRLNRNRLNSIPAKTFQLSN-LQHLDLSRNRVRRIEGLTFHGLHRLRSLKMQRNGITRLMDGAFWGLSNMEILQLEYNNLTEVSKGWLYGLLTLQQLHLAHNAISRIKPDAWEFCQKLAELDLNSNQLAR 310 HSP 2 Score: 54.6842 bits (130), Expect = 1.983e-7 Identity = 52/194 (26.80%), Postives = 97/194 (50.00%), Query Frame = 1 Query: 349 LMPQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDFS--FXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 LM F +S +E L ++ + + +L ++L+ LH++ I + + C + L+SN+++ + + +F + + L +G+NR++ I F L LDL N I+ IED + F L ++ L L N + + + GL+ L+ L LS N+I +I+ +AF +K L+ + L + LL Sbjct: 239 LMDGAFWGLSNMEILQLEYNNLTEVSKGWLYGLLTLQQLHLAHNAISRIKPDAWEFCQKLAELDLNSNQLARLEEGSFMGLSVLEQLSIGHNRVSFIADGAFRGLSLLNTLDLKYNEISWTIEDMNGPFSALNNLRKLFLQGNRIRSVTKKSFTGLDLLEQLDLSNNAIMSIQGNAFSQMKKLEELLLNTSSLL 432 HSP 3 Score: 49.2914 bits (116), Expect = 7.736e-6 Identity = 40/128 (31.25%), Postives = 64/128 (50.00%), Query Frame = 1 Query: 538 LSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 L++N+IS I+ + + LDLGNN L +R F L+NL L+ NRI+ +E NL ++ + P F L +LQ+L LS+N + IE F L L+ + +++N + R Sbjct: 112 LANNKISKISSERLRPLVALETLDLGNNNLQEVRTGAFPP-LPLKNLYLNNNRISVLEHGCLNNLSSTLLVLRLNRNRLNSIPAKTFQLSNLQHLDLSRNRVRRIEGLTFHGLHRLRSLKMQRNGITR 238
BLAST of SMED30003270 vs. Ensembl Cavefish
Match: lrrtm4l1 (leucine-rich repeat transmembrane neuronal protein 4-like [Source:NCBI gene;Acc:103034268]) HSP 1 Score: 65.4698 bits (158), Expect = 5.369e-11 Identity = 54/187 (28.88%), Postives = 91/187 (48.66%), Query Frame = 1 Query: 358 QMFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 + F+ + RL+ L++ I + N +L+ L +S +++ L G F + + L SN ++ I + F C + LDLG NRL ++ R F L L L N+ +RI F F L ++ L L N + + + + +LQ L LS N I++++ F L +L+ +NLE N L Sbjct: 100 RAFQGIRRLKELILSTNRISQLHNATFHGVPNLRSLDLSYNKLQELQPGQFHGLRKLQNLHLRSNGLTTIPIRAFIECRSLEFLDLGYNRLRILTRTAFLGLSRLMELHLEHNQFSRINLFLFPRLANLRGLYLQWNRIRAVNQGLPWIWYTLQKLDLSGNEIQSLDPVVFQCLPNLQVLNLESNKL 286
BLAST of SMED30003270 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005797.1 (pep scaffold:Pmarinus_7.0:GL476660:214761:544110:-1 gene:ENSPMAG00000005255.1 transcript:ENSPMAT00000005797.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 67.3958 bits (163), Expect = 1.715e-13 Identity = 49/158 (31.01%), Postives = 87/158 (55.06%), Query Frame = 1 Query: 439 NFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNP 912 N +L+ LH+ + ++ L G+F+ +++ L N++S + + FD + LDL N+L + L+F+ +L+ L L N++T + + F L ++K L L+ N L + + L +LQ L+L +N +++I AF NLKSL +I L NP Sbjct: 23 NLANLEKLHLYDNQLTSLPAGVFNRLVNLQKLHLYQNQMSALPNGVFDKLTELTILDLRTNQLQALPTLVFDSLGNLEVLGLCCNKLTDLPNGVFDKLTRLKQLGLDRNQLTSVPAGVFDRLGNLQKLWLHRNQLKSIPRGAFDNLKSLTHIWLFGNP 180
BLAST of SMED30003270 vs. Ensembl Sea Lamprey
Match: lrrn1 (leucine rich repeat neuronal 1 [Source:ZFIN;Acc:ZDB-GENE-071126-1]) HSP 1 Score: 70.4774 bits (171), Expect = 2.370e-13 Identity = 53/167 (31.74%), Postives = 83/167 (49.70%), Query Frame = 1 Query: 415 TIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 ++ + L N L LH+ E R+ L+ G S P + + L+ NRIS +A F ++ L L +NRL I R F L+ L + N I + +F+ L ++ L L L + E L GLE L+ L L N +E + A +L +LK+++L KNP+ Sbjct: 84 SVADVGLLNVSRLLTLHLEENRVTELADGCLSILPSLQELYLNHNRISSVAPDAFAGLGGLLRLHLNSNRLRAIDRRWFEATPHLEVLMIGENPIVGVAPANFRPLANLRSLVLAGTGLAHVPGEALLGLEKLESLSLYDNLLEAVPRAALRHLPALKFLDLNKNPV 250
BLAST of SMED30003270 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000079.1 (pep scaffold:Pmarinus_7.0:GL476403:206014:206980:-1 gene:ENSPMAG00000000071.1 transcript:ENSPMAT00000000079.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 67.3958 bits (163), Expect = 6.010e-13 Identity = 58/194 (29.90%), Postives = 97/194 (50.00%), Query Frame = 1 Query: 352 MPQMFKLVSRLETLVVQAPIQTIENQFLKNFVS-----LKILHISETRIEHLSRGMFSDCPITERIRLSSNRISV--IADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNP 912 +P M + +S +E L + +NQ L+ F + L+ LH+ E IE + + P E++ L+ N +S I TF R+ L L N L+ + R + L+ L L NRI+RI D F L + L L+ N + R+ P + +GL+ LQ + LS N + ++ + +F L+SL +++ NP Sbjct: 55 LPAMLQALSSVEVLYL------YDNQ-LEEFPAHLPPNLRELHLQENNIEVVPGAVLERTPFLEKLHLNDNSVSSAGIEPATFHGTPRLKLLFLSRNHLSSVPRGL---PRGLEELRLDDNRISRIPDRIFGQLTYLSRLALDDNQISRLPPGVFYGLKQLQRIDLSGNGLRSLSQGSFNGLESLSHLSACNNP 238
BLAST of SMED30003270 vs. Ensembl Sea Lamprey
Match: lrig3 (leucine-rich repeats and immunoglobulin-like domains 3 [Source:NCBI gene;Acc:564554]) HSP 1 Score: 69.3218 bits (168), Expect = 6.585e-13 Identity = 53/156 (33.97%), Postives = 90/156 (57.69%), Query Frame = 1 Query: 463 HISETRIEHLSRGMFSDCPITERI-RLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLRPN 927 +++ RI+ L F T +I +LS+NRI+V+ K F + +LDL NRL + L F+E SL+ L L RNRI+ + D +F L +++ + L N L + L+GL+SL++L +S+N+I ++ +A+ ++L ++L N L R N Sbjct: 1 YLNNNRIKVLRPASFDTFGATLKILKLSNNRITVLTTKLFQ-LPSLQHLDLSRNRLQRVEGLAFSELASLEYLRLQRNRISSLMDGAFWGLHRIQKIQLQHNRLTEVSTGWLYGLQSLRHLHVSRNAITAMDSEAWKFCENLWELDLSHNGLTRLN 155 HSP 2 Score: 59.6918 bits (143), Expect = 6.516e-10 Identity = 52/195 (26.67%), Postives = 89/195 (45.64%), Query Frame = 1 Query: 340 LIVLMPQMFKLVSRLETLVVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEED---AFVNLKSLKYINLEKNPL 915 + VL ++F+L S + + +Q +E SL+ L + RI L G F ++I+L NR++ ++ + +L + N +T + + +L LDLS N +TR+ + +F L ++ L+L N + I GL SL+ L L N I ED AF L +L ++L N + Sbjct: 32 ITVLTTKLFQLPSLQHLDLSRNRLQRVEGLAFSELASLEYLRLQRNRISSLMDGAFWGLHRIQKIQLQHNRLTEVSTGWLYGLQSLRHLHVSRNAITAMDSEAWKFCENLWELDLSHNGLTRLNEAAFVELGALQSLSLAHNAISHIVEGAFRGLSSLRILDLGGNQISWTVEDMQGAFTGLSALSKLSLHGNQI 226
BLAST of SMED30003270 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004666.1 (pep scaffold:Pmarinus_7.0:GL476584:91022:304495:-1 gene:ENSPMAG00000004069.1 transcript:ENSPMAT00000004666.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 61.6178 bits (148), Expect = 3.688e-11 Identity = 52/168 (30.95%), Postives = 80/168 (47.62%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNP 912 I +E + L L + ++ L G+F +++ L NR+S I FD + L L +N+LT + +FN +L+ L L N++T +F L +K L L+ N L I L +LQ+L L N +++I AF NLKSL +I L NP Sbjct: 41 ITKLEPGVFDSLTQLTYLTLRNNQLTALPEGVFDRLVNLQQLYLHLNRLSSIPAGMFDKLTNLKELKLYSNQLTALPEGLFNRLGNLEALGLCCNKLTEQPSRAFDKLTWLKYLGLDGNQLKSIPAGCLTAWGNLQWLSLHVNQLKSIPRGAFDNLKSLTHIWLYNNP 208 HSP 2 Score: 48.1358 bits (113), Expect = 1.111e-6 Identity = 49/149 (32.89%), Postives = 76/149 (51.01%), Query Frame = 1 Query: 472 ETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFG-LESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 E R+ + G+ + T+ + L +N+I+ + FDS ++ L L NN+LT + +F+ +LQ L L NR++ I F L +K L L +N L + PE LF L +L+ L L N + AF L LKY+ L+ N L Sbjct: 17 ERRLASVPAGIPT---TTQVLYLYTNKITKLEPGVFDSLTQLTYLTLRNNQLTALPEGVFDRLVNLQQLYLHLNRLSSIPAGMFDKLTNLKELKLYSNQLTAL-PEGLFNRLGNLEALGLCCNKLTEQPSRAFDKLTWLKYLGLDGNQL 161
BLAST of SMED30003270 vs. Ensembl Nematostella
Match: EDO49136 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGZ6]) HSP 1 Score: 69.707 bits (169), Expect = 6.587e-13 Identity = 59/228 (25.88%), Postives = 110/228 (48.25%), Query Frame = 1 Query: 415 TIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKN-SIETIEEDAF--VNLKSLKYINLEKNPLLRPNMXXXXXXXXXXXXXXGVKCVDEQYSDYSKVSINVSNEFEKYPICSGIRKRNETG 1089 T+ +L+N L L++ +I++++ G F+D E + LS N+++ I++ F + L L N + + +F +L+ L ++RN IT++ F+N ++ L ++ N L IKP G +L+ L L+ N +++T+E+D F NL +L+ + + L+R M Q+ D+ KV + +S KYPI + R + G Sbjct: 65 TVTRGYLRNLRQLLELNLGMNQIDYIASGTFTDMAKLELLDLSGNQLTFISEGMFTGLRNLTTLFLFMNEILDLPASLFWGTPNLKILSINRNNITKLHQHLFRNSLHLEYLFMDDNNLTTIKPNTFKGARALEILSLTNNVALKTVEDDTFNVANLPNLRLMYILNTQLVRIRM--------------------SQFKDHQKVGVVISPTVAKYPIMAANDSRLQGG 272
BLAST of SMED30003270 vs. Ensembl Nematostella
Match: EDO48179 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK32]) HSP 1 Score: 60.8474 bits (146), Expect = 9.053e-10 Identity = 51/162 (31.48%), Postives = 88/162 (54.32%), Query Frame = 1 Query: 451 LKILHISETRIEHLSRGMFSDC---PITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDFS--FXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 L+ L++ +I + F+D P+ ++ L NR+S I D TF + L+L NNR+ I + F++ SL+ LDLS N I+ +E+ + F+ L + L L+ N + I GLE+++YL LS N I +I+E++F + L+ + L + L+ Sbjct: 321 LQNLYLQSNQISTIITTKFADWRSFPVLRKLNLERNRLSHIQDTTFKHLLALKVLNLANNRIYHISQGSFSDLRSLEGLDLSNNDISWTVEEMNGPFRGLTNLASLRLDGNRITAIAATAFLGLENIKYLNLSANIITSIQENSFQGMDKLQKLWLNTSQLM 482 HSP 2 Score: 55.4546 bits (132), Expect = 3.961e-8 Identity = 55/173 (31.79%), Postives = 81/173 (46.82%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILH-ISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKS---LKYINLEKNPL 915 I +I + N +L+ L+ I+ R L+ DC +L NR++ + + LDL N T I FN SL+ L LS+NRI+ I +F K++ L L+ N I+ FGL LQ L+L N I TI F + +S L+ +NLE+N L Sbjct: 191 ISSIGHHAFTNLSNLQNLYSIAYLRYTSLTEYKKEDCIK----KLGKNRLTSVPSDALSQLQSLKRLDLSRNFFTSILASAFNRLSSLEVLKLSKNRISTIRG-AFWGQNKLQQLYLDRNNFTAIQTSSFFGLRDLQNLYLQSNQISTIITTKFADWRSFPVLRKLNLERNRL 358
BLAST of SMED30003270 vs. Ensembl Nematostella
Match: EDO39412 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SA74]) HSP 1 Score: 56.6102 bits (135), Expect = 1.429e-8 Identity = 43/184 (23.37%), Postives = 95/184 (51.63%), Query Frame = 1 Query: 367 KLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 +++ RL L + + I I N FL F +L+ L++S ++E L +F++ + + +++N + + +F + R+++L L NN+L + + + L++L ++ N++ +++ +F ++++ NL+ + + GL SLQ + +N + + F N SLK + L N L Sbjct: 174 RVMDRLSYLWLSSTGITEIPNGFLDYFPALEALYLSNNKLEQLPSALFNNNTRLQYLYINNNELEHLHSSSFSNNARLLHLSLVNNKLVRLPLYLLSNNTKLESLSIAYNQLEYLQNDTFFYNADLQIIIFENNLITSLPENLTDGLNSLQIISFPRNKLSKVPSKIFQNKPSLKIVFLGMNNL 357 HSP 2 Score: 51.9878 bits (123), Expect = 4.014e-7 Identity = 43/164 (26.22%), Postives = 74/164 (45.12%), Query Frame = 1 Query: 433 LKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLES-LQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 LK L IL++S ++ + G F D + + N+I +AD F + + LD+G N++ + + L L LS IT I + F + +N + P LF + LQYL+++ N +E + +F N L +++L N L+R Sbjct: 101 LKGLRRLTILYLSNNFLDSIPGGCFLDLKSLKHFFVGDNQIKKVADDVFQNVSNGFKLDIGRNKMNGVPDAVKRVMDRLSYLWLSSTGITEIPN-GFLDYFPALEALYLSNNKLEQLPSALFNNNTRLQYLYINNNELEHLHSSSFSNNARLLHLSLVNNKLVR 263
BLAST of SMED30003270 vs. Ensembl Nematostella
Match: EDO35407 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLJ8]) HSP 1 Score: 52.373 bits (124), Expect = 1.208e-7 Identity = 49/177 (27.68%), Postives = 89/177 (50.28%), Query Frame = 1 Query: 394 VVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDL--SRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEI---LFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 V ++P++ ++N +++ LK L +S I + G F + +++ L N+I ++ F + LDL N L + R +F SL+ L L +RN +RIE+ +F L ++ L+++A + +I L LE L L ++ NS+ T+ A +K LK ++L N Sbjct: 1 VSRSPLKLLKNTSFQDYQYLKWLDLSNNDISDIQDGTFENLRYLKQLNLGENKIRTVSASMFKGLVSLEKLDLRFNDLKALPRGVFKPLKSLRELFLHDNRNMGSRIEEGAFNGLDNLRKLHVSATGMKKITQGTFGSLMSLEFLDVLHINNNSLTTVPLHALRKVKFLKELDLSAN 177
BLAST of SMED30003270 vs. Ensembl Nematostella
Match: EDO31669 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXA1]) HSP 1 Score: 51.9878 bits (123), Expect = 4.146e-7 Identity = 43/140 (30.71%), Postives = 76/140 (54.29%), Query Frame = 1 Query: 448 SLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAF 867 +K L++ I+ + G F + E + LS N++ + FD+ + + L L +NRLT + R +F+ SL+ L L RN+I IE ++F +LK + L L++N L I + L GL +++ + + N + + DAF Sbjct: 120 GMKKLNLRRNGIKEIEFGAFRNLTALESLILSKNKLRRLTYAMFDTLSYLRLLSLVDNRLTGLTRSMFSGLKSLRELYLQRNQIQDIEPWTFTSLKSLASLYLDSNQLTVISRDTLLGLTNVKDIHVYFNKLRYVARDAF 259 HSP 2 Score: 49.6766 bits (117), Expect = 2.215e-6 Identity = 49/157 (31.21%), Postives = 74/157 (47.13%), Query Frame = 1 Query: 517 PITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMR------------------------IKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 P T + L+ NR+S++ F N + LDL NR + IR F ++ L+L RN I IE +F+NL ++ L L+ N L R + + GL+SL+ L+L +N I+ IE F +LKSL + L+ N L Sbjct: 71 PRTSTLLLNDNRLSLLRYDFFLGLNNIRTLDLSGNRFSKIRFNTFGYLPGMKKLNLRRNGIKEIEFGAFRNLTALESLILSKNKLRRLTYAMFDTLSYLRLLSLVDNRLTGLTRSMFSGLKSLRELYLQRNQIQDIEPWTFTSLKSLASLYLDSNQL 227
BLAST of SMED30003270 vs. Ensembl Medaka
Match: igfals (insulin like growth factor binding protein acid labile subunit [Source:NCBI gene;Acc:101172904]) HSP 1 Score: 82.4185 bits (202), Expect = 2.291e-16 Identity = 58/167 (34.73%), Postives = 96/167 (57.49%), Query Frame = 1 Query: 415 TIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 T++ Q K SL +H+ R+ L +F + P + L +N+IS I ++ F + + L+LG N LTV+ +F++ HSL+ L L+ NR+ ++ F+NL ++K L+L N + IK + L LQ L+L++N I TI AFV +KSL++++L N L Sbjct: 106 TLDPQAFKGLRSLAHVHLERNRLRALPGTIFQNTPNLASLSLHNNQISRIDERLFAGLSHMWLLNLGWNSLTVLPETVFHDLHSLRELILAGNRLAYLQPQLFQNLVELKELDLTGNHVKVIKANVFVKLTKLQKLYLARNQIVTIVPRAFVGMKSLRWLDLTNNKL 272 HSP 2 Score: 59.3066 bits (142), Expect = 4.477e-9 Identity = 58/211 (27.49%), Postives = 100/211 (47.39%), Query Frame = 1 Query: 271 RFNADLLAACQRISGLLITTESSLIVLMPQMFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINL 900 R + L A + LL +SL VL +F + L L++ + ++ Q +N V LK L ++ ++ + +F +++ L+ N+I I + F + LDL NN+LT + F HSL L LS N +T I +F++L+ ++ L L+ N + + I GL L+ L L N ++ + +F L + INL Sbjct: 154 RIDERLFAGLSHM-WLLNLGWNSLTVLPETVFHDLHSLRELILAGNRLAYLQPQLFQNLVELKELDLTGNHVKVIKANVFVKLTKLQKLYLARNQIVTIVPRAFVGMKSLRWLDLTNNKLTSLHEDTFLGLHSLHVLRLSNNSVTGIRPRTFRDLQYLEELQLSHNKIRVLGERIFDGLGHLEVLELQHNQVQEAQMGSFTGLSHVAVINL 363 HSP 3 Score: 49.2914 bits (116), Expect = 7.146e-6 Identity = 45/185 (24.32%), Postives = 86/185 (46.49%), Query Frame = 1 Query: 319 LITTESSLIVLMPQMFKLVSRLETL-VVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFV 870 L + ++ ++P+ F + L L + + ++ SL +L +S + + F D E ++LS N+I V+ ++ FD + L+L +N++ + F + ++LS + + + D FK L K+ L+L+ L RI + GL L+ LFL N+I +E +F Sbjct: 241 LYLARNQIVTIVPRAFVGMKSLRWLDLTNNKLTSLHEDTFLGLHSLHVLRLSNNSVTGIRPRTFRDLQYLEELQLSHNKIRVLGERIFDGLGHLEVLELQHNQVQEAQMGSFTGLSHVAVINLSGSCFSSLPDQMFKGLSKLHSLHLDRGCLTRIPAQAFVGLSGLRRLFLQHNNISVVEYRSFA 425
BLAST of SMED30003270 vs. Ensembl Medaka
Match: lrrn3b (leucine rich repeat neuronal 3 [Source:NCBI gene;Acc:101158247]) HSP 1 Score: 69.3218 bits (168), Expect = 4.223e-12 Identity = 51/174 (29.31%), Postives = 88/174 (50.57%), Query Frame = 1 Query: 400 QAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 Q + +I + L N L LH+ E ++ L S+ + + ++ N IS I+ F + +V L L +N+LTVI+R F +L+ L + N + I+D +FK L ++ L L L + + L GL+ L+ + N + A N+K+LK+++L KNP+ R Sbjct: 101 QNNLSSISDIHLGNLSQLISLHMEENWLQRLPEQCLSNVANLQELYMNHNLISYISPMAFQGMSNLVRLHLNSNKLTVIQREWFEPMPNLEILMIGENPVLSIDDMNFKPLSNLRSLVLTRMNLSHLPEKALTGLDKLESISFYDNIFPEVPHSALKNVKNLKFLDLNKNPIAR 274
BLAST of SMED30003270 vs. Ensembl Medaka
Match: lrig1 (leucine rich repeats and immunoglobulin like domains 1 [Source:NCBI gene;Acc:101171324]) HSP 1 Score: 69.3218 bits (168), Expect = 4.409e-12 Identity = 86/293 (29.35%), Postives = 132/293 (45.05%), Query Frame = 1 Query: 124 EEPCQKKCRCKHKE-KSSKIEVAHCTVDEKDTFVSCNVEWPILLMTVKKLRFNADLLAACQRISGLLITTESSLIVLMPQMFKLVSRLETLVVQAP-IQTIENQFLKNFVSLKILHISETRIEHLSRGMF-----------SDCPIT--------------ERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLR 921 E PC + C C S++E+ +D VS N L K N + A+ + L + + + + +P + SR+ +L + I++I+ + ++ VS++ L +S I L F S+ I+ + +RLS NRIS I + F R+ L+L NR+ I L F SL+ L L RN I+++ D +F +L KMKVL+L N L + L+GL SL LFLS NSI I D + L+ +NL N L R Sbjct: 33 ELPCAQNCTCDGDSVDCSRLELTATPLDLPARTVSLN------LGHNKLTSINPEAFASLPNLRELHL--DHNELTSIPDLGHFASRIVSLYLHHNNIRSIDGRRIRELVSVETLDLSNNEITELRGHCFPAGLQIRDLYLSNNKISVLELGALDRLGSSLQVLRLSRNRISQIPIRAF-QLPRLTQLELNRNRIRQIEGLTFQGLSSLEVLKLQRNSISKLTDGAFWDLAKMKVLHLEYNNLTEVNSGSLYGLTSLTQLFLSNNSIARINPDGLKFCQRLRELNLSYNNLTR 316 HSP 2 Score: 49.2914 bits (116), Expect = 9.501e-6 Identity = 54/213 (25.35%), Postives = 96/213 (45.07%), Query Frame = 1 Query: 364 FKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDL------------------------GNNRLTVIRRLIFNEGHSLQNLDLSRNRIT-RIEDF--SFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLL 918 F+ +S LE L +Q I + + + +K+LH+ + ++ G ++ LS+N I+ I C R+ L+L G+N ++ I F +++ L+L N I+ IED +F L ++ L L N + + E GLESL++L L +N I +I+ DAF +++LK + ++ N L Sbjct: 226 FQGLSSLEVLKLQRNSISKLTDGAFWDLAKMKVLHLEYNNLTEVNSGSLYGLTSLTQLFLSNNSIARINPDGLKFCQRLRELNLSYNNLTRLDEGSLAMLGDLHTLRLGHNSISQINEGAFRGLKAVRILELDHNDISGTIEDTNGAFSGLDRLNKLTLFGNKIKSVAKEAFSGLESLEHLNLGENPIRSIQPDAFSKMRNLKNLIMDSNSFL 438
BLAST of SMED30003270 vs. Ensembl Medaka
Match: ENSORLT00000000072.2 (pep primary_assembly:ASM223467v1:1:1576629:1604541:-1 gene:ENSORLG00000000055.2 transcript:ENSORLT00000000072.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 68.1662 bits (165), Expect = 5.080e-12 Identity = 46/169 (27.22%), Postives = 77/169 (45.56%), Query Frame = 1 Query: 409 IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 + I L L++LH+ E +I ++ RG F + ER+RL+ NR+S + + F + LDL NR+ + R F L+NL L +N I+ +E+ +F+ L SL+ L L+ N+I +I +F ++ L+ L N L Sbjct: 84 LTVITKSDLSGLRHLRVLHLMENQISNIERGAFDELKELERLRLNRNRLSQLPELLFQKNEALSRLDLSENRIQAVPRRAFRGAADLKNLQLDKNHISCVEEGAFR------------------------ALRSLEVLTLNNNNISSIPVSSFNHMPKLRTFRLHSNSL 228 HSP 2 Score: 55.4546 bits (132), Expect = 5.473e-8 Identity = 40/129 (31.01%), Postives = 68/129 (52.71%), Query Frame = 1 Query: 523 TERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 TER+ L+ N ++VI + L L N+++ I R F+E L+ L L+RNR++++ + F+ + + L+L+ N + + G L+ L L KN I +EE AF L+SL+ + L N Sbjct: 74 TERLDLNGNNLTVITKSDLSGLRHLRVLHLMENQISNIERGAFDELKELERLRLNRNRLSQLPELLFQKNEALSRLDLSENRIQAVPRRAFRGAADLKNLQLDKNHISCVEEGAFRALRSLEVLTLNNN 202
BLAST of SMED30003270 vs. Ensembl Medaka
Match: lrrtm4l1 (leucine-rich repeat transmembrane neuronal protein 4-like [Source:NCBI gene;Acc:101154965]) HSP 1 Score: 67.781 bits (164), Expect = 1.131e-11 Identity = 58/187 (31.02%), Postives = 92/187 (49.20%), Query Frame = 1 Query: 358 QMFKLVSRLETLVVQA-PIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPL 915 + F+ V RL+ L++ + I ++ N +L+ L +S ++E L G F + + L SN +S I + F C + LDLG NR+ + R F L L L N+ TRI F F L ++ L L N + + + + +LQ L LS N I+T++ F L +L+ +NLE N L Sbjct: 121 RAFQGVRRLKELILSSNRITSLHNSTFHGIPNLRSLDLSFNKLEILQPGQFHGLRKLQNLHLRSNGLSNIPIRVFLECRSLEFLDLGYNRIKALTRTTFLGLQRLMELHLEHNQFTRINFFLFPRLANLRSLYLQWNRIRVVNQGLPWIWYTLQKLDLSGNEIQTLDPAVFHCLPNLQVLNLESNKL 307
BLAST of SMED30003270 vs. Planmine SMEST
Match: SMESG000052792.1 (SMESG000052792.1) HSP 1 Score: 756.133 bits (1951), Expect = 0.000e+0 Identity = 418/419 (99.76%), Postives = 418/419 (99.76%), Query Frame = 1 Query: 85 NYSAQTYFEGGLIEEPCQKKCRCKHKEKSSKIEVAHCTVDEKDTFVSCNVEWPILLMTVKKLRFNADLLAACQRISGLLITTESSLIVLMPQMFKLVSRLETLVVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLRPNMXXXXXXXXXXXXXXGVKCVDEQYSDYSKVSINVSNEFEKYPICSGIRKRNETGENKPLIQNSESKNPQPNPTKVWKTSVGPSIFDLHPYLFPMIFGGXXXXXXXXXXXXXXCHIKNQQINELRLQELQNLPMMQSTL 1341 NYSAQTYFEGGLIEEPCQKKCRCKHKEKSSKIEVAHCTVDEKDTFVSCNVEWPILLMTVKKLRFNADLLAACQRISGLLITTESSLIVLMPQMFKLVSRLETLVVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFKNLKKMKVLNLNANLLMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLRPNMVLFLNLDNLTVLLTGVKCVDEQYSDYSKVSINVSNEFEKYPICSGIRKRNETGENKPLIQNSESKNPQPNPTKVWKTSVGPSIFDLHPYLFPMIFGGLSVLLISIIVIA VCHIKNQQINELRLQELQNLPMMQSTL Sbjct: 16 NYSAQTYFEGGLIEEPCQKKCRCKHKEKSSKIEVAHCTVDEKDTFVSCNVEWPILLMTVKKLRFNADLLAACQRISGLLITTESSLIVLMPQMFKLVSRLETLVVQAPIQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFKNLKKMKVLNLNANLLMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLRPNMVLFLNLDNLTVLLTGVKCVDEQYSDYSKVSINVSNEFEKYPICSGIRKRNETGENKPLIQNSESKNPQPNPTKVWKTSVGPSIFDLHPYLFPMIFGGLSVLLISIIVIAFVCHIKNQQINELRLQELQNLPMMQSTL 434
BLAST of SMED30003270 vs. Planmine SMEST
Match: SMESG000045574.1 (SMESG000045574.1) HSP 1 Score: 63.1586 bits (152), Expect = 1.693e-10 Identity = 68/290 (23.45%), Postives = 128/290 (44.14%), Query Frame = 1 Query: 133 CQKKCRCKHKEKSSKIEVAHCTVDEKDTFVSCNVEWPILLMTVK-KLRFNAD---LLAACQRISGLLITTESSLIVLMPQMFKLVSR-LETLVVQAP--IQTIENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCN--RVVNLD----------------------LGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKN 909 C C+C V C+V + + C V W I + V + + +D L C + I I +P + + R LE L++ P I ++ +N + LK ++ ++ ++ +F+ C + + L++N I VI + F +C R +NL L +NR++ I+ F+ + +++L+ N++ ++ SF N+ M L LN N + I + GL++LQYL L N + +EE F +K L+ + L+++ Sbjct: 7 CPNHCQCD--------GVVKCSVVQSHQSIFCPVNWEITSIIVSITMPYKSDWNNLFLNCSTSNITAIMINPGNIRSVPASYFVDFRNLEKLIINGPGIIDRLDEGIFRNRIHLKKFKMTSNKLTIITEKLFNSCSTLQELSLANNMIKVIFELAFHTCKNLRFINLSHNLLLGIYEKTFEGLVNLYVLILAHNRISFIKPFAFSSLRKIHSIELNHNQLLSLDIRSFFNIHSMIRLLLNDNQIRDISMKAFKGLDNLQYLSLKNNKLMLLEESMFSEMKRLETVELDED 288
BLAST of SMED30003270 vs. Planmine SMEST
Match: SMESG000017864.1 (SMESG000017864.1) HSP 1 Score: 51.6026 bits (122), Expect = 1.317e-6 Identity = 48/157 (30.57%), Postives = 76/157 (48.41%), Query Frame = 1 Query: 454 KILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGL-ESLQYLFLSKNSIETIEEDAFVNLKSLK--YINLEKNPL 915 + L I +T LS G+FS + +S N I + + FD + L L N + ++ F LQ LD++ N IT IE F+F NL + + L + L I G+ E+L + +S N I +I +D+FV + +L IN+ KN + Sbjct: 1398 RTLTIVQTHSLELSSGIFSQFIYLGYLNISDNSILELYNGLFDGLFNLRYLILSKNYIRILPSYAFQFLKQLQILDITDNPITTIESFAFHNLISITHIELPSMKLYEINDYTFLGMSENLISINMSNNDIRSISQDSFVGVNNLSTLVINVNKNDI 1554
BLAST of SMED30003270 vs. Planmine SMEST
Match: SMESG000047911.1 (SMESG000047911.1) HSP 1 Score: 50.8322 bits (120), Expect = 1.664e-6 Identity = 44/149 (29.53%), Postives = 68/149 (45.64%), Query Frame = 1 Query: 442 FVSLKILHISET-RIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSL 885 F K+ H++ T +I++L+ F ER+ L N ++VI+ TF +V ++L N + + F L +LDLS N ++ I D E+ + +LQ L LS N+I IE +AFV LKSL Sbjct: 253 FAVKKLKHLNMTMKIKNLTALTFYGLTDLERLELQGNHLTVISPGTFQQVQKVTIINLSRNAIRCLLPETFRNLPKLLSLDLSYNDLSYISD------------------------EVFSEISTLQTLDLSDNNIYVIERNAFVGLKSL 377
BLAST of SMED30003270 vs. Planmine SMEST
Match: SMESG000045664.1 (SMESG000045664.1) HSP 1 Score: 50.8322 bits (120), Expect = 1.664e-6 Identity = 44/149 (29.53%), Postives = 68/149 (45.64%), Query Frame = 1 Query: 442 FVSLKILHISET-RIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRIEDFSFXXXXXXXXXXXXXXXXMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSL 885 F K+ H++ T +I++L+ F ER+ L N ++VI+ TF +V ++L N + + F L +LDLS N ++ I D E+ + +LQ L LS N+I IE +AFV LKSL Sbjct: 253 FAVKKLKHLNMTMKIKNLTALTFYGLTDLERLELQGNHLTVISPGTFQQVQKVTIINLSRNAIRCLLPETFRNLPKLLSLDLSYNDLSYISD------------------------EVFSEISTLQTLDLSDNNIYVIERNAFVGLKSL 377 The following BLAST results are available for this feature:
BLAST of SMED30003270 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of SMED30003270 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of SMED30003270 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of SMED30003270 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of SMED30003270 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of SMED30003270 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of SMED30003270 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of SMED30003270 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of SMED30003270 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of SMED30003270 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of SMED30003270 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of SMED30003270 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of SMED30003270 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of SMED30003270 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30003270 ID=SMED30003270|Name=SMED30003270|organism=Schmidtea mediterranea sexual|type=transcript|length=1428bpback to top protein sequence of SMED30003270-orf-1 >SMED30003270-orf-1 ID=SMED30003270-orf-1|Name=SMED30003270-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=435bp MKKLLYILLVIILTLNYSAQTYFEGGLIEEPCQKKCRCKHKEKSSKIEVAback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|