Prohibitin

Overview


Name	Prohibitin
Smed ID	SMED30003249
Length (bp)	1005

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Prohibitin (SMED30003249) t-SNE clustered cells

Violin plots show distribution of expression levels for Prohibitin (SMED30003249) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Prohibitin (SMED30003249) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Prohibitin (SMED30003249) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30003249

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 20

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30003249	h1SMcG0005004	SmedASXL_004762	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30003249	h1SMcG0005004	SmedASXL_004762	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
Smed sexual biotype	SMED30003249	h1SMcG0005004	Contig23393	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30003249	h1SMcG0005004	Contig23393	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30003249	h1SMcG0005004	Contig49497	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30003249	h1SMcG0005004	Contig49497	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
pharynx	SMED30003249	h1SMcG0005004	dd_Smed_v4_1038_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30003249	h1SMcG0005004	dd_Smed_v4_1038_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30003249	h1SMcG0005004	dd_Smed_v4_1038_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30003249	h1SMcG0005004	dd_Smed_v4_1038_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30003249	h1SMcG0005004	dd_Smed_v4_1038_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30003249	h1SMcG0005004	dd_Smed_v4_1038_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30003249	h1SMcG0005004	dd_Smed_v4_1038_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30003249	h1SMcG0005004	dd_Smed_v4_1038_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30003249	h1SMcG0005004	SMED30003249	smed_20140614	PMID:22696458 Labbé et al., 2012
X1 cell	SMED30003249	h1SMcG0005004	isotig10463	be_Smed_v2	PMID:22543868 Onal et al., 2012
gamma neoblast	SMED30003249	h1SMcG0005004	dd_Smed_v6_1038_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
neoblast	SMED30003249	h1SMcG0005004	dd_Smed_v6_1038_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
Category 1 cell	SMED30003249	h1SMcG0005004	NB.32.8d	smed_ncbi_20240424	PMID:18786419 Eisenhoffer et al., 2008
Category 1 cell	SMED30003249	h1SMcG0005004	NB.32.8d	smed_ncbi_20240424	PMID:18786419 Eisenhoffer et al., 2008

Note: Hover over icons to view figure legend

Homology

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BLAST of Prohibitin vs. Ensembl Human
Match: PHB (prohibitin [Source:HGNC Symbol;Acc:HGNC:8912])

HSP 1 Score: 355.525 bits (911), Expect = 6.329e-123
Identity = 180/267 (67.42%), Postives = 225/267 (84.27%), Query Frame = 3

Query:  135 VFDLLAKFXXXXXXXXXXXXXXLYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            VF+ + KFG+A+AVAGGV +SALY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRNVPV TGSKDLQ VNITLRIL++P A  LP+I+T++G D++ERVLPSIT E+LK+VVA+FDA +LITQRELVS +V++ LT RA+ FGL+LDD+SLTHLTFG EF++AVE KQVAQQEAERARF+VEKAEQ+K AAIISAEGDS+AA L+A S    G+G IEL++++ +E+IA  LS+++NI YLP  Q  L+ LP
Sbjct:    5 VFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLP 271

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Query:  135 VFDLLAKFXXXXXXXXXXXXXXLYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            VF+ + KFG+A+AVAGGV +SALY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRNVPV TGSKDLQ VNITLRIL++P A  LP+I+T++G D++ERVLPSIT E+LK+VVA+FDA +LITQRELVS +V++ LT RA+ FGL+LDD+SLTHLTFG EF++AVE KQVAQQEAERARF+VEKAEQ+K AAIISAEGDS+AA L+A S    G+G IEL++++ +E+IA  LS+++NI YLP  Q  L+ LP
Sbjct:    5 VFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLP 271

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Query:  135 VFDLLAKFXXXXXXXXXXXXXXLYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            VF+ + KFG+A+AVAGGV +SALY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRNVPV TGSKDLQ VNITLRIL++P A  LP+I+T++G D++ERVLPSIT E+LK+VVA+FDA +LITQRELVS +V++ LT RA+ FGL+LDD+SLTHLTFG EF++AVE KQVAQQEAERARF+VEKAEQ+K AAIISAEGDS+AA L+A S    G+G IEL++++ +E+IA  LS+++NI YLP  Q  L+ LP
Sbjct:    5 VFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLP 271

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BLAST of Prohibitin vs. Ensembl Human
Match: PHB (prohibitin [Source:HGNC Symbol;Acc:HGNC:8912])

HSP 1 Score: 330.102 bits (845), Expect = 2.465e-113
Identity = 167/242 (69.01%), Postives = 208/242 (85.95%), Query Frame = 3

Query:  135 VFDLLAKFXXXXXXXXXXXXXXLYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEE 860
            VF+ + KFG+A+AVAGGV +SALY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRNVPV TGSKDLQ VNITLRIL++P A  LP+I+T++G D++ERVLPSIT E+LK+VVA+FDA +LITQRELVS +V++ LT RA+ FGL+LDD+SLTHLTFG EF++AVE KQVAQQEAERARF+VEKAEQ+K AAIISAEGDS+AA L+A S    G+G IEL++++ +E+
Sbjct:    5 VFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAED 246

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BLAST of Prohibitin vs. Ensembl Human
Match: PHB (prohibitin [Source:HGNC Symbol;Acc:HGNC:8912])

HSP 1 Score: 300.827 bits (769), Expect = 3.589e-102
Identity = 154/212 (72.64%), Postives = 186/212 (87.74%), Query Frame = 3

Query:  135 VFDLLAKFXXXXXXXXXXXXXXLYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEG 770
            VF+ + KFG+A+AVAGGV +SALY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRNVPV TGSKDLQ VNITLRIL++P A  LP+I+T++G D++ERVLPSIT E+LK+VVA+FDA +LITQRELVS +V++ LT RA+ FGL+LDD+SLTHLTFG EF++AVE KQVAQQEAERARF+VEKAEQ+K AAIISAEG
Sbjct:    5 VFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEG 216

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BLAST of Prohibitin vs. Ensembl Celegans
Match: phb-1 (Mitochondrial prohibitin complex protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9BKU4])

HSP 1 Score: 325.094 bits (832), Expect = 2.219e-111
Identity = 160/244 (65.57%), Postives = 201/244 (82.38%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISL 932
            LY V GG RAVIFDR SGV+ +V+GEGTHFLIPW+QKPII+DIR+ PR V   TGSKDLQ VNITLRIL++P  + LP IY N+GLD+ ERVLPSIT EVLK VVAQFDA ++ITQRE+VS + +  L  RA+ FGL+LDDI++THL FG EF++AVE+KQVAQQEAE+AR+LVEKAEQ K+AA+ +AEGD+QAA LLAK+F   G+G +EL++I+ +EEIA  ++KNKN+ YLP  Q TL++L
Sbjct:   30 LYNVDGGQRAVIFDRFSGVKNEVVGEGTHFLIPWVQKPIIFDIRSTPRAVTTITGSKDLQNVNITLRILHRPSPDRLPNIYLNIGLDYAERVLPSITNEVLKAVVAQFDAHEMITQREVVSQRASVALRERAAQFGLLLDDIAITHLNFGREFTEAVEMKQVAQQEAEKARYLVEKAEQMKIAAVTTAEGDAQAAKLLAKAFASAGDGLVELRKIEAAEEIAERMAKNKNVTYLPGNQQTLLNL 273

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BLAST of Prohibitin vs. Ensembl Celegans
Match: phb-2 (Mitochondrial prohibitin complex protein 2 [Source:UniProtKB/Swiss-Prot;Acc:P50093])

HSP 1 Score: 250.366 bits (638), Expect = 9.178e-82
Identity = 124/235 (52.77%), Postives = 170/235 (72.34%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLP 905
            ++TV  GHRA++F+RI G+  D+  EG HF IPW Q PIIYDIR RP  +   TGSKDLQ VNI LR+L +P  E L  IY  LG ++EERVLPSI  EVLK VVA+F+AS LITQR+ VS  V + L  RA +F ++LDD+SLT L F  ++S AVE KQVA QEA+RA F VE+A+Q+K   I+ AEG++++A LL ++  +   GF++L++I+ +++IAR++S++ N  YLP
Sbjct:   40 MFTVEAGHRAIMFNRIGGLSTDLYKEGLHFRIPWFQYPIIYDIRARPNQIRSPTGSKDLQMVNIGLRVLSRPNPEHLVHIYRTLGQNWEERVLPSICNEVLKGVVAKFNASQLITQRQQVSMLVRKTLIERALDFNIILDDVSLTELAFSPQYSAAVEAKQVAAQEAQRATFYVERAKQQKQEKIVQAEGEAESAKLLGEAM-KNDPGFLKLRKIRAAQKIARIVSESGNKTYLP 273

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Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLP 905
            ++TV  GHRA++F+RI G+  D+  EG HF IPW Q PIIYDIR RP  +   TGSKDLQ VNI LR+L +P  E L  IY  LG ++EERVLPSI  EVLK VVA+F+AS LITQR+ VS  V + L  RA +F ++LDD+SLT L F  ++S AVE KQVA QEA+RA F VE+A+Q+K   I+ AEG++++A LL ++  +   GF++L++I+ +++IAR++S++ N  YLP
Sbjct:   40 MFTVEAGHRAIMFNRIGGLSTDLYKEGLHFRIPWFQYPIIYDIRARPNQIRSPTGSKDLQMVNIGLRVLSRPNPEHLVHIYRTLGQNWEERVLPSICNEVLKGVVAKFNASQLITQRQQVSMLVRKTLIERALDFNIILDDVSLTELAFSPQYSAAVEAKQVAAQEAQRATFYVERAKQQKQEKIVQAEGEAESAKLLGEAM-KNDPGFLKLRKIRAAQKIARIVSESGNKTYLP 273

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BLAST of Prohibitin vs. Ensembl Fly
Match: l(2)37Cc (gene:FBgn0002031 transcript:FBtr0081164)

HSP 1 Score: 360.918 bits (925), Expect = 2.072e-125
Identity = 168/246 (68.29%), Postives = 210/246 (85.37%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLPA 938
            LY V GGHRAVIFDR +G++ +V+GEGTHF IPW+Q+PII+DIR++PRNVPV TGSKDLQ VNITLRILY+P  + LPKIYT LG D++ERVLPSI  EVLK VVAQFDA +LITQRE+VS +V++ LT RA  FG +LDDISLTHLTFG EF+ AVE+KQVAQQEAE+ARF+VEKAEQ+KLA+IISAEGD++AA LLAKSF + G+G +EL+RI+ +E+IA  LS+++ + YLP  Q TL++LP+
Sbjct:   27 LYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPIIFDIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAVVAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEKARFVVEKAEQQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYLPSGQSTLLNLPS 272

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BLAST of Prohibitin vs. Ensembl Fly
Match: l(2)37Cc (gene:FBgn0002031 transcript:FBtr0081165)

HSP 1 Score: 360.918 bits (925), Expect = 2.072e-125
Identity = 168/246 (68.29%), Postives = 210/246 (85.37%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLPA 938
            LY V GGHRAVIFDR +G++ +V+GEGTHF IPW+Q+PII+DIR++PRNVPV TGSKDLQ VNITLRILY+P  + LPKIYT LG D++ERVLPSI  EVLK VVAQFDA +LITQRE+VS +V++ LT RA  FG +LDDISLTHLTFG EF+ AVE+KQVAQQEAE+ARF+VEKAEQ+KLA+IISAEGD++AA LLAKSF + G+G +EL+RI+ +E+IA  LS+++ + YLP  Q TL++LP+
Sbjct:   27 LYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPIIFDIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAVVAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEKARFVVEKAEQQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYLPSGQSTLLNLPS 272

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BLAST of Prohibitin vs. Ensembl Fly
Match: l(2)37Cc (gene:FBgn0002031 transcript:FBtr0346428)

HSP 1 Score: 360.918 bits (925), Expect = 2.072e-125
Identity = 168/246 (68.29%), Postives = 210/246 (85.37%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLPA 938
            LY V GGHRAVIFDR +G++ +V+GEGTHF IPW+Q+PII+DIR++PRNVPV TGSKDLQ VNITLRILY+P  + LPKIYT LG D++ERVLPSI  EVLK VVAQFDA +LITQRE+VS +V++ LT RA  FG +LDDISLTHLTFG EF+ AVE+KQVAQQEAE+ARF+VEKAEQ+KLA+IISAEGD++AA LLAKSF + G+G +EL+RI+ +E+IA  LS+++ + YLP  Q TL++LP+
Sbjct:   27 LYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPIIFDIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAVVAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEKARFVVEKAEQQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYLPSGQSTLLNLPS 272

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BLAST of Prohibitin vs. Ensembl Fly
Match: Phb2 (gene:FBgn0010551 transcript:FBtr0086614)

HSP 1 Score: 258.84 bits (660), Expect = 6.704e-85
Identity = 120/234 (51.28%), Postives = 175/234 (74.79%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            LYTV GGHRA+IF R+ G++ D+  EG H  IPW Q PIIYDIR+RPR +   TGSKDLQ +NI+LR+L +P +  LP ++  LG+D++E+VLPSI  EVLK+V+A+F+AS LITQR+ VS  + + L  RA +F ++LDD+SLT L+FG E++ A+E KQVAQQEA+RA F VE+A+QEK   I+ AEG+++AA +L  +  Q    +++L++++ ++ IAR ++ ++N VYL
Sbjct:   42 LYTVEGGHRAIIFSRLGGIQSDIYSEGLHVRIPWFQYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKVLPSICNEVLKSVIAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSLTELSFGKEYTAAIEAKQVAQQEAQRAVFFVERAKQEKQQKIVQAEGEAEAAKMLGLAVKQ-NPAYLKLRKLRAAQSIARTIASSQNKVYL 274

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BLAST of Prohibitin vs. Ensembl Fly
Match: Phb2 (gene:FBgn0010551 transcript:FBtr0086615)

HSP 1 Score: 258.84 bits (660), Expect = 6.704e-85
Identity = 120/234 (51.28%), Postives = 175/234 (74.79%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            LYTV GGHRA+IF R+ G++ D+  EG H  IPW Q PIIYDIR+RPR +   TGSKDLQ +NI+LR+L +P +  LP ++  LG+D++E+VLPSI  EVLK+V+A+F+AS LITQR+ VS  + + L  RA +F ++LDD+SLT L+FG E++ A+E KQVAQQEA+RA F VE+A+QEK   I+ AEG+++AA +L  +  Q    +++L++++ ++ IAR ++ ++N VYL
Sbjct:   42 LYTVEGGHRAIIFSRLGGIQSDIYSEGLHVRIPWFQYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKVLPSICNEVLKSVIAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSLTELSFGKEYTAAIEAKQVAQQEAQRAVFFVERAKQEKQQKIVQAEGEAEAAKMLGLAVKQ-NPAYLKLRKLRAAQSIARTIASSQNKVYL 274

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BLAST of Prohibitin vs. Ensembl Zebrafish
Match: phb (prohibitin [Source:ZFIN;Acc:ZDB-GENE-030131-6577])

HSP 1 Score: 360.147 bits (923), Expect = 5.917e-125
Identity = 170/245 (69.39%), Postives = 209/245 (85.31%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            LY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRNVPV TGSKDLQ VNITLRIL++P A  LP+I+T++G D++ERVLPSIT EVLK+VVA+FDA +LITQRELVS +V+E LT RAS FGL+LDD+SLTHLTFG EF++AVE+KQVAQQEAERARF+VEKAEQ+K AAIISAEGDSQAA L+A S  + G+G +EL++++ +E+IA  LS+ +N+ YLP  QGTL+ LP
Sbjct:   26 LYNVDAGHRAVIFDRFRGVQDVVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVAGQLPRIFTSIGEDYDERVLPSITTEVLKSVVARFDAGELITQRELVSRQVSEDLTERASTFGLILDDVSLTHLTFGKEFTEAVEMKQVAQQEAERARFVVEKAEQQKQAAIISAEGDSQAALLIANSLAEAGDGLVELRKLEAAEDIAFQLSRARNVTYLPSGQGTLLQLP 270

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BLAST of Prohibitin vs. Ensembl Zebrafish
Match: phb2b (prohibitin 2b [Source:ZFIN;Acc:ZDB-GENE-040718-430])

HSP 1 Score: 255.758 bits (652), Expect = 1.508e-83
Identity = 128/234 (54.70%), Postives = 173/234 (73.93%), Query Frame = 3

Query:  204 YTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            YTV GG RA+IF+RI GV+ D V+ EG HF IPW Q PIIYDIR RPR +   TGSKDLQ VNI LR+L +P A  LP +Y  LG D++ERVLPSI  EVLK+VVA+F+AS LITQR  VS  +   L  RA +F ++LDD+++T L+F  E++ AVE KQVAQQEA+RA+F VEKA+QE+   II AEG++QAA +L ++  +   G+++L+RI+ ++ IA+ ++ ++N VYL
Sbjct:   49 YTVEGGQRAIIFNRIGGVQLDTVLTEGLHFRIPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIALRVLSRPLASNLPIMYQQLGQDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELFERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFFVEKAKQEQKQKIIQAEGEAQAAKMLGEAVTK-NPGYLKLRRIRAAQNIAKTVAASQNKVYL 281

[Close]

Query:  204 YTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            YTV GG RA+IF+RI GV+ D V+ EG HF IPW Q PIIYDIR RPR +   TGSKDLQ VNI LR+L +P A  LP +Y  LG D++ERVLPSI  EVLK+VVA+F+AS LITQR  VS  +   L  RA +F ++LDD+++T L+F  E++ AVE KQVAQQEA+RA+F VEKA+QE+   II AEG++QAA +L ++  +   G+++L+RI+ ++ IA+ ++ ++N VYL
Sbjct:   49 YTVEGGQRAIIFNRIGGVQLDTVLTEGLHFRIPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIALRVLSRPLASNLPIMYQQLGQDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELFERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFFVEKAKQEQKQKIIQAEGEAQAAKMLGEAVTK-NPGYLKLRRIRAAQNIAKTVAASQNKVYL 281

[Close]

Query:  204 YTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            YTV GG RA+IF+RI GV+ D V+ EG HF IPW Q PIIYDIR RPR +   TGSKDLQ VNI LR+L +P A  LP +Y  LG D++ERVLPSI  EVLK+VVA+F+AS LITQR  VS  +   L  RA +F ++LDD+++T L+F  E++ AVE KQVAQQEA+RA+F VEKA+QE+   II AEG++QAA +L ++  +   G+++L+RI+ ++ IA+ ++ ++N VYL
Sbjct:   49 YTVEGGQRAIIFNRIGGVQLDTVLTEGLHFRIPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIALRVLSRPLASNLPIMYQQLGQDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELFERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFFVEKAKQEQKQKIIQAEGEAQAAKMLGEAVTK-NPGYLKLRRIRAAQNIAKTVAASQNKVYL 281

[Close]

BLAST of Prohibitin vs. Ensembl Zebrafish
Match: phb2a (prohibitin 2a [Source:ZFIN;Acc:ZDB-GENE-030131-3141])

HSP 1 Score: 252.677 bits (644), Expect = 2.590e-82
Identity = 125/234 (53.42%), Postives = 172/234 (73.50%), Query Frame = 3

Query:  204 YTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            YTV GG RAVIF RI G++ D V+ EG HF +PW Q PIIYDIR RPR +   TGSKDLQ VNI LR+L +P A  LP +Y  LG D++ERVLPSI  EVLK+VVA+F+AS LITQR  VS  +   L  RA +F ++LDD+++T L+F  E++ AVE KQVAQQEA+RA+F VEKA+Q++   II AEG+++AA +L ++  +   G+++L+RI+ ++ IA+ ++ ++N VYL
Sbjct:   49 YTVEGGQRAVIFSRIGGMQMDTVLAEGLHFRMPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIGLRVLSRPVASQLPIMYQQLGKDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRDLIERAKDFNIILDDVAITELSFSKEYTAAVEAKQVAQQEAQRAQFFVEKAKQDQRQKIIQAEGEAEAAKMLGQAVTK-NPGYLKLRRIRAAQNIAKTVAASQNKVYL 281

[Close]

BLAST of Prohibitin vs. Ensembl Xenopus
Match: phb (prohibitin [Source:NCBI gene;Acc:394635])

HSP 1 Score: 350.132 bits (897), Expect = 6.871e-121
Identity = 174/267 (65.17%), Postives = 221/267 (82.77%), Query Frame = 3

Query:  135 VFDLLAKFXXXXXXXXXXXXXXLYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            +F+ + K G+ +AVAGGV +SALY V  GH+AVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRNVPV TGSKDLQ VNITLRIL++P    LP+I+T++G D++ERVLPSIT E+LK+VVA+FDA +LITQRELVS +V+E L  RA+ FGL+LDD+SLTHLTFG EF++AVE KQVAQQEAERARF+VEKAEQ+K AA+ISAEGDS+AA L+A S    G+G IEL++++ +E+IA  LS+ +N+ YLP  Q TL+ LP
Sbjct:    5 LFETIGKLGLGLAVAGGVVNSALYNVDAGHQAVIFDRFRGVQETVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVVTGSKDLQNVNITLRILFRPMGNQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSEDLMERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFIVEKAEQQKKAAVISAEGDSKAAELIATSLADAGDGLIELRKLEAAEDIAYQLSRARNVTYLPSGQSTLLQLP 271

[Close]

BLAST of Prohibitin vs. Ensembl Xenopus
Match: cgref1 (cell growth regulator with EF-hand domain 1 [Source:Xenbase;Acc:XB-GENE-997667])

HSP 1 Score: 258.84 bits (660), Expect = 1.085e-84
Identity = 125/235 (53.19%), Postives = 176/235 (74.89%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            ++TV GGHRA+ F+RI GV+ D ++ EG HF  PW Q PIIYDIR RPR +   TGSKDLQ VNITLR+L +P A  LP +Y  LGLD++ERVLPSI  EVLK+VVA+F+AS LITQR  VS  +   LT RA +F ++LDD+++T L+F  E++ AVE KQVAQQEA+RA+FLVEKA+Q++   I+ AEG++ AA ++  + ++   G+++L+RI+ ++ IA+ ++ ++N VYL
Sbjct:   40 VFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRFPWFQYPIIYDIRARPRKISSPTGSKDLQMVNITLRVLSRPLASELPFMYQRLGLDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSIILDDVAITELSFSREYTAAVESKQVAQQEAQRAQFLVEKAKQDQKQKIVQAEGEAAAAKMIGDALSK-NPGYLKLRRIRAAQSIAKTIASSQNRVYL 273

[Close]

Query:  201 LYTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            ++TV GGHRA+ F+RI GV+ D ++ EG HF  PW Q PIIYDIR RPR +   TGSKDLQ VNITLR+L +P A  LP +Y  LGLD++ERVLPSI  EVLK+VVA+F+AS LITQR  VS  +   LT RA +F ++LDD+++T L+F  E++ AVE KQVAQQEA+RA+FLVEKA+Q++   I+ AEG++ AA ++  + ++   G+++L+RI+ ++ IA+ ++ ++N VYL
Sbjct:   40 VFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRFPWFQYPIIYDIRARPRKISSPTGSKDLQMVNITLRVLSRPLASELPFMYQRLGLDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSIILDDVAITELSFSREYTAAVESKQVAQQEAQRAQFLVEKAKQDQKQKIVQAEGEAAAAKMIGDALSK-NPGYLKLRRIRAAQSIAKTIASSQNRVYL 273

[Close]

BLAST of Prohibitin vs. Ensembl Xenopus
Match: cgref1 (cell growth regulator with EF-hand domain 1 [Source:Xenbase;Acc:XB-GENE-997667])

HSP 1 Score: 259.225 bits (661), Expect = 1.088e-84
Identity = 125/235 (53.19%), Postives = 176/235 (74.89%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            ++TV GGHRA+ F+RI GV+ D ++ EG HF  PW Q PIIYDIR RPR +   TGSKDLQ VNITLR+L +P A  LP +Y  LGLD++ERVLPSI  EVLK+VVA+F+AS LITQR  VS  +   LT RA +F ++LDD+++T L+F  E++ AVE KQVAQQEA+RA+FLVEKA+Q++   I+ AEG++ AA ++  + ++   G+++L+RI+ ++ IA+ ++ ++N VYL
Sbjct:   40 VFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRFPWFQYPIIYDIRARPRKISSPTGSKDLQMVNITLRVLSRPLASELPFMYQRLGLDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSIILDDVAITELSFSREYTAAVESKQVAQQEAQRAQFLVEKAKQDQKQKIVQAEGEAAAAKMIGDALSK-NPGYLKLRRIRAAQSIAKTIASSQNRVYL 273

[Close]

BLAST of Prohibitin vs. Ensembl Mouse
Match: Phb (prohibitin [Source:MGI Symbol;Acc:MGI:97572])

HSP 1 Score: 357.066 bits (915), Expect = 9.514e-124
Identity = 181/267 (67.79%), Postives = 225/267 (84.27%), Query Frame = 3

Query:  135 VFDLLAKFXXXXXXXXXXXXXXLYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            VF+ + KFG+A+AVAGGV +SALY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRNVPV TGSKDLQ VNITLRIL++P A  LP+IYT++G D++ERVLPSIT E+LK+VVA+FDA +LITQRELVS +V++ LT RA+ FGL+LDD+SLTHLTFG EF++AVE KQVAQQEAERARF+VEKAEQ+K AAIISAEGDS+AA L+A S    G+G IEL++++ +E+IA  LS+++NI YLP  Q  L+ LP
Sbjct:    5 VFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLP 271

[Close]

BLAST of Prohibitin vs. Ensembl Mouse
Match: Phb (prohibitin [Source:MGI Symbol;Acc:MGI:97572])

HSP 1 Score: 288.5 bits (737), Expect = 1.262e-97
Identity = 147/203 (72.41%), Postives = 178/203 (87.68%), Query Frame = 3

Query:  135 VFDLLAKFXXXXXXXXXXXXXXLYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEK 743
            VF+ + KFG+A+AVAGGV +SALY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRNVPV TGSKDLQ VNITLRIL++P A  LP+IYT++G D++ERVLPSIT E+LK+VVA+FDA +LITQRELVS +V++ LT RA+ FGL+LDD+SLTHLTFG EF++AVE KQVAQQEAERARF+VEKAEQ+K
Sbjct:    5 VFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQK 207

[Close]

BLAST of Prohibitin vs. Ensembl Mouse
Match: Phb2 (prohibitin 2 [Source:MGI Symbol;Acc:MGI:102520])

HSP 1 Score: 266.544 bits (680), Expect = 9.405e-88
Identity = 127/235 (54.04%), Postives = 180/235 (76.60%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            ++TV GGHRA+ F+RI GV+ D ++ EG HF IPW Q PIIYDIR RPR +   TGSKDLQ VNI+LR+L +P A+ LP +Y  LGLD+EERVLPSI  EVLK+VVA+F+AS LITQR  VS  +   LT RA +F L+LDD+++T L+F  E++ AVE KQVAQQEA+RA+FLVEKA+QE+   I+ AEG+++AA +L ++ ++   G+I+L++I+ ++ I++ ++ ++N +YL
Sbjct:   40 VFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSK-NPGYIKLRKIRAAQNISKTIATSQNRIYL 273

[Close]

BLAST of Prohibitin vs. Ensembl Mouse
Match: Phb2 (prohibitin 2 [Source:MGI Symbol;Acc:MGI:102520])

HSP 1 Score: 135.961 bits (341), Expect = 1.909e-39
Identity = 64/101 (63.37%), Postives = 77/101 (76.24%), Query Frame = 3

Query:  270 IGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKV 572
            + EG HF IPW Q PIIYDIR RPR +   TGSKDLQ VNI+LR+L +P A+ LP +Y  LGLD+EERVLPSI  EVLK+VVA+F+AS LITQR   S+ +
Sbjct:    1 LAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQFSDPL 101

[Close]

BLAST of Prohibitin vs. Ensembl Mouse
Match: Phb2 (prohibitin 2 [Source:MGI Symbol;Acc:MGI:102520])

HSP 1 Score: 120.168 bits (300), Expect = 8.784e-33
Identity = 69/181 (38.12%), Postives = 104/181 (57.46%), Query Frame = 3

Query:  360 TGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            TGSKDLQ VNI+LR+L +P A+ LP +Y  LGLD+EERVLPSI  EVLK+VVA+F+AS LITQR                                                    A+FLVEKA+QE+   I+ AEG+++AA +L ++ ++   G+I+L++I+ ++ I++ ++ ++N +YL
Sbjct:    4 TGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQR----------------------------------------------------AQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSK-NPGYIKLRKIRAAQNISKTIATSQNRIYL 131

[Close]

BLAST of Prohibitin vs. UniProt/SwissProt
Match: sp|P24156|L2CC_DROME (Protein l(2)37Cc OS=Drosophila melanogaster OX=7227 GN=l(2)37Cc PE=2 SV=2)

HSP 1 Score: 360.918 bits (925), Expect = 2.077e-124
Identity = 168/246 (68.29%), Postives = 210/246 (85.37%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLPA 938
            LY V GGHRAVIFDR +G++ +V+GEGTHF IPW+Q+PII+DIR++PRNVPV TGSKDLQ VNITLRILY+P  + LPKIYT LG D++ERVLPSI  EVLK VVAQFDA +LITQRE+VS +V++ LT RA  FG +LDDISLTHLTFG EF+ AVE+KQVAQQEAE+ARF+VEKAEQ+KLA+IISAEGD++AA LLAKSF + G+G +EL+RI+ +E+IA  LS+++ + YLP  Q TL++LP+
Sbjct:   27 LYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPIIFDIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAVVAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEKARFVVEKAEQQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYLPSGQSTLLNLPS 272

[Close]

BLAST of Prohibitin vs. UniProt/SwissProt
Match: sp|P67779|PHB_RAT (Prohibitin OS=Rattus norvegicus OX=10116 GN=Phb PE=1 SV=1)

HSP 1 Score: 357.066 bits (915), Expect = 6.655e-123
Identity = 181/267 (67.79%), Postives = 225/267 (84.27%), Query Frame = 3

Query:  135 VFDLLAKFXXXXXXXXXXXXXXLYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            VF+ + KFG+A+AVAGGV +SALY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRNVPV TGSKDLQ VNITLRIL++P A  LP+IYT++G D++ERVLPSIT E+LK+VVA+FDA +LITQRELVS +V++ LT RA+ FGL+LDD+SLTHLTFG EF++AVE KQVAQQEAERARF+VEKAEQ+K AAIISAEGDS+AA L+A S    G+G IEL++++ +E+IA  LS+++NI YLP  Q  L+ LP
Sbjct:    5 VFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLP 271

[Close]

BLAST of Prohibitin vs. UniProt/SwissProt
Match: sp|P67778|PHB_MOUSE (Prohibitin OS=Mus musculus OX=10090 GN=Phb PE=1 SV=1)

HSP 1 Score: 357.066 bits (915), Expect = 6.655e-123
Identity = 181/267 (67.79%), Postives = 225/267 (84.27%), Query Frame = 3

Query:  135 VFDLLAKFXXXXXXXXXXXXXXLYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            VF+ + KFG+A+AVAGGV +SALY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRNVPV TGSKDLQ VNITLRIL++P A  LP+IYT++G D++ERVLPSIT E+LK+VVA+FDA +LITQRELVS +V++ LT RA+ FGL+LDD+SLTHLTFG EF++AVE KQVAQQEAERARF+VEKAEQ+K AAIISAEGDS+AA L+A S    G+G IEL++++ +E+IA  LS+++NI YLP  Q  L+ LP
Sbjct:    5 VFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLP 271

[Close]

BLAST of Prohibitin vs. UniProt/SwissProt
Match: sp|P84173|PHB_CHICK (Prohibitin OS=Gallus gallus OX=9031 GN=PHB PE=1 SV=1)

HSP 1 Score: 356.681 bits (914), Expect = 1.112e-122
Identity = 177/267 (66.29%), Postives = 224/267 (83.90%), Query Frame = 3

Query:  135 VFDLLAKFXXXXXXXXXXXXXXLYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            VF+ + KFG+ +AVAGGV +SALY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRN+PV TGSKDLQ VNITLRIL++P    LP+I+T++G D++ERVLPSIT E+LK+VVA+FDA +LITQRELVS +V+E LT RA+ FGL+LDD+SLTHLTFG EF++AVE+KQVAQQEAERARF+VEKAEQ+K AA+ISAEGDS+AA L+A S    G+G IEL++++ +E+IA  LS+++NI YLP  Q  L+ LP
Sbjct:    5 VFESIGKFGLGLAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDTVVGEGTHFLIPWVQKPIIFDCRSRPRNIPVITGSKDLQNVNITLRILFRPVTAQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSEDLTERAATFGLILDDVSLTHLTFGKEFTEAVEMKQVAQQEAERARFIVEKAEQQKKAAVISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPSGQSVLLQLP 271

[Close]

BLAST of Prohibitin vs. UniProt/SwissProt
Match: sp|P35232|PHB_HUMAN (Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1)

HSP 1 Score: 355.525 bits (911), Expect = 3.039e-122
Identity = 180/267 (67.42%), Postives = 225/267 (84.27%), Query Frame = 3

Query:  135 VFDLLAKFXXXXXXXXXXXXXXLYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            VF+ + KFG+A+AVAGGV +SALY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRNVPV TGSKDLQ VNITLRIL++P A  LP+I+T++G D++ERVLPSIT E+LK+VVA+FDA +LITQRELVS +V++ LT RA+ FGL+LDD+SLTHLTFG EF++AVE KQVAQQEAERARF+VEKAEQ+K AAIISAEGDS+AA L+A S    G+G IEL++++ +E+IA  LS+++NI YLP  Q  L+ LP
Sbjct:    5 VFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLP 271

[Close]

BLAST of Prohibitin vs. TrEMBL
Match: A0A430QDG4 (Prohibitin OS=Schistosoma bovis OX=6184 GN=DC041_0004608 PE=3 SV=1)

HSP 1 Score: 389.423 bits (999), Expect = 3.766e-133
Identity = 186/246 (75.61%), Postives = 214/246 (86.99%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLPA 938
            LY V GGHRAVIFDR  GVRPDV GEGTHF+IPW+QKPII+DIR+RPRNVPV TGSKDLQ VNITLRIL++P+   LPKIY NLG D+EERVLPSIT EVLK VVAQFDAS+LITQRELVS +VNE LT RAS+FG++LDDI+LT ++FG EFS+AVE KQVAQQEAERAR+LVEKAEQ KLAAIISAEGDS+AA LL+KSF   GEG IEL+RI+ +E+IA  LSKN+NI Y+PD Q TL++LPA
Sbjct:   26 LYNVDGGHRAVIFDRFKGVRPDVRGEGTHFIIPWVQKPIIFDIRSRPRNVPVMTGSKDLQTVNITLRILFRPEPSTLPKIYQNLGFDYEERVLPSITTEVLKAVVAQFDASELITQRELVSQRVNEDLTQRASSFGILLDDIALTQISFGREFSEAVEAKQVAQQEAERARYLVEKAEQHKLAAIISAEGDSEAATLLSKSFGSSGEGLIELRRIEAAEDIAYQLSKNRNITYIPDGQHTLLNLPA 271

[Close]

BLAST of Prohibitin vs. TrEMBL
Match: A0A5K4FC32 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 389.037 bits (998), Expect = 5.300e-133
Identity = 186/246 (75.61%), Postives = 214/246 (86.99%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLPA 938
            LY V GGHRAVIFDR  GVRPDV GEGTHF+IPW+QKPII+DIR+RPRNVPV TGSKDLQ VNITLRIL++P+   LPKIY NLG D+EERVLPSIT EVLK VVAQFDAS+LITQRELVS +VNE LT RAS+FG++LDDI+LT ++FG EFS+AVE KQVAQQEAERAR+LVEKAEQ KLAAIISAEGDS+AA LL+KSF   GEG IEL+RI+ +E+IA  LSKN+NI Y+PD Q TL++LPA
Sbjct:   27 LYNVDGGHRAVIFDRFKGVRPDVRGEGTHFIIPWVQKPIIFDIRSRPRNVPVMTGSKDLQTVNITLRILFRPEPSTLPKIYQNLGFDYEERVLPSITTEVLKAVVAQFDASELITQRELVSQRVNEDLTQRASSFGILLDDIALTQISFGREFSEAVEAKQVAQQEAERARYLVEKAEQHKLAAIISAEGDSEAATLLSKSFGSSGEGLIELRRIEAAEDIAYQLSKNRNITYIPDGQHTLLNLPA 272

[Close]

BLAST of Prohibitin vs. TrEMBL
Match: A0A0V0J2R0 (Prohibitin (Fragment) OS=Schistocephalus solidus OX=70667 GN=L2CC PE=3 SV=1)

HSP 1 Score: 388.652 bits (997), Expect = 7.151e-133
Identity = 183/245 (74.69%), Postives = 217/245 (88.57%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            LY V GGHRAVIFDR  GVR +VIGEGTHF+IPW+QKPIIYDIR++PRN+PV TGSKDLQ VNITLRILY+PKAE+LPKIY+NLG D+EERVLPSIT EVLK VVAQFDAS+LITQRE+VS +V++ LT RAS+FG++LDDI+LT ++F TEF+ AVE KQVAQQEAERARFLVEKAEQ+KLAA+ISAEGDS+AA LLAK+F   G+G IEL+RI+TSE+IA  LSKN+N+ YLPD Q  L++LP
Sbjct:   20 LYNVDGGHRAVIFDRFKGVRENVIGEGTHFIIPWVQKPIIYDIRSKPRNIPVMTGSKDLQNVNITLRILYRPKAELLPKIYSNLGFDYEERVLPSITTEVLKAVVAQFDASELITQREVVSQRVSDSLTERASSFGILLDDIALTQISFSTEFAAAVEAKQVAQQEAERARFLVEKAEQQKLAAVISAEGDSEAATLLAKAFGGSGDGLIELRRIETSEDIAYQLSKNRNVSYLPDGQHALLNLP 264

[Close]

BLAST of Prohibitin vs. TrEMBL
Match: A0A183TP29 (Prohibitin OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS18227 PE=3 SV=1)

HSP 1 Score: 388.652 bits (997), Expect = 8.831e-133
Identity = 183/245 (74.69%), Postives = 217/245 (88.57%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            LY V GGHRAVIFDR  GVR +VIGEGTHF+IPW+QKPIIYDIR++PRN+PV TGSKDLQ VNITLRILY+PKAE+LPKIY+NLG D+EERVLPSIT EVLK VVAQFDAS+LITQRE+VS +V++ LT RAS+FG++LDDI+LT ++F TEF+ AVE KQVAQQEAERARFLVEKAEQ+KLAA+ISAEGDS+AA LLAK+F   G+G IEL+RI+TSE+IA  LSKN+N+ YLPD Q  L++LP
Sbjct:   30 LYNVDGGHRAVIFDRFKGVRENVIGEGTHFIIPWVQKPIIYDIRSKPRNIPVMTGSKDLQNVNITLRILYRPKAELLPKIYSNLGFDYEERVLPSITTEVLKAVVAQFDASELITQREVVSQRVSDSLTERASSFGILLDDIALTQISFSTEFAAAVEAKQVAQQEAERARFLVEKAEQQKLAAVISAEGDSEAATLLAKAFGGSGDGLIELRRIETSEDIAYQLSKNRNVSYLPDGQHALLNLP 274

[Close]

BLAST of Prohibitin vs. TrEMBL
Match: Q5DE25 (Prohibitin OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 386.726 bits (992), Expect = 5.155e-132
Identity = 185/246 (75.20%), Postives = 214/246 (86.99%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLPA 938
            LY V GGHRAVIFDR  GVR DV GEGTHF+IPW+QKPII+DIR+RPRNVPV TGSKDLQ VNITLRIL++P+  +LPKIY NLG D+EERVLPSIT EVLK VVAQFDAS+LITQRELVS +VNE LT RAS+FG++LDDI+LT ++FG EFS+AVE KQVAQQEAERAR+LVEKAEQ KLAAIISAEGDS+AA LL+KSF   GEG IEL+RI+ +E+IA  LSKN+NI Y+PD Q TL++LPA
Sbjct:   27 LYNVEGGHRAVIFDRFKGVRSDVRGEGTHFIIPWVQKPIIFDIRSRPRNVPVMTGSKDLQTVNITLRILFRPEPSVLPKIYQNLGFDYEERVLPSITTEVLKAVVAQFDASELITQRELVSQRVNEDLTERASSFGILLDDIALTQISFGREFSEAVEAKQVAQQEAERARYLVEKAEQHKLAAIISAEGDSEAATLLSKSFGSSGEGLIELRRIEAAEDIAYQLSKNRNITYIPDGQHTLLNLPA 272

[Close]

BLAST of Prohibitin vs. Ensembl Cavefish
Match: phb (prohibitin [Source:NCBI gene;Acc:103031128])

HSP 1 Score: 356.295 bits (913), Expect = 1.331e-123
Identity = 168/245 (68.57%), Postives = 207/245 (84.49%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            L+ V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKPII+D R+RPRNVPV TGSKDLQ VNITLRIL++P A  LP+I+T++G D++ERVLPSIT EVLK VVA+FDA +LITQRELVS +V+E LT RAS FGL+LDD+SLTHLTFG EF++AVE+KQVAQQEAERARF+VEKAEQ+K AAIISA GDSQAA L+A S    G+G +EL++++ +E+IA  LS+++N+ YLP  QGTL+ LP
Sbjct:   26 LFNVDAGHRAVIFDRFRGVQDAVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVVTGSKDLQNVNITLRILFRPVANQLPRIFTSIGEDYDERVLPSITTEVLKAVVARFDAGELITQRELVSRQVSEDLTERASTFGLILDDVSLTHLTFGKEFTEAVEMKQVAQQEAERARFVVEKAEQQKQAAIISAAGDSQAALLIADSLAVAGDGLVELRKLEAAEDIAFQLSRSRNVTYLPSGQGTLLQLP 270

[Close]

BLAST of Prohibitin vs. Ensembl Cavefish
Match: phb2a (prohibitin-2-like [Source:NCBI gene;Acc:103035142])

HSP 1 Score: 254.988 bits (650), Expect = 2.675e-83
Identity = 125/235 (53.19%), Postives = 175/235 (74.47%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            +YTV GG RA+IF+RI G+  D V+ EG HF IPW Q PIIYDIR RPR +   TGSKDLQ VNI LR+L +P A  LP +Y +LG+D++ERVLPSI  EVLK+VVA+F+AS LITQR  VS  +   L  RA +F ++LDD+++T L+F  E++ AVE KQVAQQEA+RA+F VEKA+Q++   II AEG+++AA LL ++  +   G+++L+RI+ ++ IA+ ++ ++N +YL
Sbjct:   48 MYTVEGGQRAIIFNRIGGMEKDTVLAEGLHFRIPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIALRVLSRPVASNLPFLYQHLGVDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSMLIRRELIERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFYVEKAKQDQRQKIIQAEGEAEAAKLLGEAVTK-NPGYLKLRRIRAAQNIAKTVASSQNKLYL 281

[Close]

BLAST of Prohibitin vs. Ensembl Cavefish
Match: phb2b (prohibitin-2-like [Source:NCBI gene;Acc:103047478])

HSP 1 Score: 251.521 bits (641), Expect = 6.557e-82
Identity = 122/234 (52.14%), Postives = 174/234 (74.36%), Query Frame = 3

Query:  204 YTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            YTV GG RA++F+R+ G++ D V+ EG HF IPW Q PIIYDIR +PR +   TGSKDLQ VNI LR+L +P A  LP +Y +LG D++ERVLPSI  EVLK+VVA+F+AS L+TQR  VS  +   L  RA +F ++LDD+++T L+F  E++ AVE KQVAQQEA+RA+F VEKA+QE+   II AEG+++AA +L ++  +   G+++L+RI+ ++ IA+ ++ ++N VYL
Sbjct:   49 YTVEGGQRAIVFNRVGGMQMDTVLSEGLHFRIPWFQYPIIYDIRAKPRKISSLTGSKDLQMVNIALRVLSRPVASNLPYMYQHLGKDYDERVLPSIVNEVLKSVVAKFNASQLLTQRAQVSLLIRRELFERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFFVEKAKQEQKQKIIQAEGEAEAAKMLGEAVTK-NPGYLKLRRIRAAQNIAKTVAASQNKVYL 281

[Close]

BLAST of Prohibitin vs. Ensembl Cavefish
Match: phb2a (prohibitin-2-like [Source:NCBI gene;Acc:103035142])

HSP 1 Score: 248.44 bits (633), Expect = 3.668e-80
Identity = 123/227 (54.19%), Postives = 169/227 (74.45%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLS 878
            +YTV GG RA+IF+RI G+  D V+ EG HF IPW Q PIIYDIR RPR +   TGSKDLQ VNI LR+L +P A  LP +Y +LG+D++ERVLPSI  EVLK+VVA+F+AS LITQR  VS  +   L  RA +F ++LDD+++T L+F  E++ AVE KQVAQQEA+RA+F VEKA+Q++   II AEG+++AA LL ++  +   G+++L+RI+ ++ IA+ +S
Sbjct:   48 MYTVEGGQRAIIFNRIGGMEKDTVLAEGLHFRIPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIALRVLSRPVASNLPFLYQHLGVDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSMLIRRELIERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFYVEKAKQDQRQKIIQAEGEAEAAKLLGEAVTK-NPGYLKLRRIRAAQNIAKTVS 273

[Close]

BLAST of Prohibitin vs. Ensembl Cavefish
Match: phb2b (prohibitin-2-like [Source:NCBI gene;Acc:103047478])

HSP 1 Score: 242.662 bits (618), Expect = 1.103e-78
Identity = 125/239 (52.30%), Postives = 172/239 (71.97%), Query Frame = 3

Query:  204 YTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQT----SEEIARLLSKN-KNIVYL 902
            YTV GG RA++F+R+ G++ D V+ EG HF IPW Q PIIYDIR +PR +   TGSKDLQ VNI LR+L +P A  LP +Y +LG D++ERVLPSI  EVLK+VVA+F+AS L+TQR  VS  +   L  RA +F ++LDD+++T L+F  E++ AVE KQVAQQEA+RA+F VEKA+QE+   II AEG+++AA +L ++  +   G+++L+RI+     +   +  LSKN KN VYL
Sbjct:   30 YTVEGGQRAIVFNRVGGMQMDTVLSEGLHFRIPWFQYPIIYDIRAKPRKISSLTGSKDLQMVNIALRVLSRPVASNLPYMYQHLGKDYDERVLPSIVNEVLKSVVAKFNASQLLTQRAQVSLLIRRELFERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFFVEKAKQEQKQKIIQAEGEAEAAKMLGEAVTK-NPGYLKLRRIRAVFLLTVVCSCFLSKNRKNKVYL 267

[Close]

BLAST of Prohibitin vs. Ensembl Sea Lamprey
Match: phb (prohibitin [Source:ZFIN;Acc:ZDB-GENE-030131-6577])

HSP 1 Score: 344.354 bits (882), Expect = 1.805e-119
Identity = 161/244 (65.98%), Postives = 204/244 (83.61%), Query Frame = 3

Query:  207 TVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLPA 938
            TV GGHRAVIFDR  GV+  V+GEGTHF+IPW+Q+PII+D R+RPRNVPV TGSKD+Q VNITLRIL++P A  LPKIY ++G D++ERVLPSIT EVLK VVA+FDA +LITQRELVS +V+  L  RA+ FGL+LDD+SLTHLTFG EF+ AVE KQVAQQEAERARF+VE+AEQ+K AAII+AEGD++AA L+A + ++ GEG +EL++++ +E+IA  LSK++ + YLP  Q TL+ LPA
Sbjct:   27 TVEGGHRAVIFDRFRGVQDLVVGEGTHFVIPWVQRPIIFDCRSRPRNVPVVTGSKDMQNVNITLRILFRPIASQLPKIYMSIGEDYDERVLPSITTEVLKAVVARFDAGELITQRELVSRQVSNDLMERAATFGLILDDVSLTHLTFGREFTQAVEAKQVAQQEAERARFVVERAEQQKKAAIIAAEGDAKAAQLIATAISEAGEGLVELRKLEAAEDIAMQLSKSRGVAYLPSGQHTLLQLPA 270

[Close]

BLAST of Prohibitin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006512.1 (pep scaffold:Pmarinus_7.0:GL479067:257:4164:-1 gene:ENSPMAG00000005886.1 transcript:ENSPMAT00000006512.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 154.836 bits (390), Expect = 7.992e-47
Identity = 73/120 (60.83%), Postives = 91/120 (75.83%), Query Frame = 3

Query:  204 YTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELV 560
            YTV GG RA+IF R+ G++ + ++ EG HF IPW   PIIYDIR +PR +   TGSKDLQ VNITLR+L +P A  LP+++  LGLD+EERVLPSI  EVLK+VVA+F+AS LITQR  V
Sbjct:   41 YTVDGGQRAIIFSRLGGIQENTILAEGLHFRIPWFHYPIIYDIRAKPRKISSPTGSKDLQMVNITLRVLSRPDALKLPRMFQQLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQV 160

[Close]

BLAST of Prohibitin vs. Ensembl Yeast
Match: PHB1 (Subunit of the prohibitin complex (Phb1p-Phb2p); prohibitin is a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation; prohibitin deficiency induces a mitochondrial unfolded protein response (mtUPR) [Source:SGD;Acc:S000003364])

HSP 1 Score: 310.457 bits (794), Expect = 4.053e-106
Identity = 134/238 (56.30%), Postives = 198/238 (83.19%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQ 914
            +Y V GG R VIFDRI+GV+  V+GEGTHFL+PW+QK IIYD+RT+P+++  NTG+KDLQ V++TLR+L++P+   LP IY NLGLD++ERVLPSI  EVLK++VAQFDA++LITQRE++S K+ + L++RA+ FG+ L+D+S+TH+TFG EF+ AVE KQ+AQQ+AERA+FLVEKAEQE+ A++I AEG++++A  ++K+  + G+G + ++R++ S++IA+ L+ + N+VYLP + 
Sbjct:   29 MYDVKGGSRGVIFDRINGVKQQVVGEGTHFLVPWLQKAIIYDVRTKPKSIATNTGTKDLQMVSLTLRVLHRPEVLQLPAIYQNLGLDYDERVLPSIGNEVLKSIVAQFDAAELITQREIISQKIRKELSTRANEFGIKLEDVSITHMTFGPEFTKAVEQKQIAQQDAERAKFLVEKAEQERQASVIRAEGEAESAEFISKALAKVGDGLLLIRRLEASKDIAQTLANSSNVVYLPSQH 266

[Close]

BLAST of Prohibitin vs. Ensembl Yeast
Match: PHB2 (Subunit of the prohibitin complex (Phb1p-Phb2p); prohibitin is a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation; prohibitin deficiency induces a mitochondrial unfolded protein response (mtUPR) [Source:SGD;Acc:S000003463])

HSP 1 Score: 260.381 bits (664), Expect = 3.688e-86
Identity = 123/243 (50.62%), Postives = 177/243 (72.84%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLIS 929
            L+ V GGHRA+++ RI GV   +  EGTHF+ PW+  PIIYD+R +PRNV   TG+KDLQ VNIT R+L +P    LP IY  LG D++ERVLPSI  EVLK VVAQF+AS LITQRE VS  + E L  RAS F ++LDD+S+T++TF  EF++AVE KQ+AQQ+A+RA F+V+KA QEK   ++ A+G++++A L+ ++  +  + ++EL+R+ T+ +IA++L+ + N V L D +  L++
Sbjct:   58 LFNVDGGHRAIVYSRIHGVSSRIFNEGTHFIFPWLDTPIIYDVRAKPRNVASLTGTKDLQMVNITCRVLSRPDVVQLPTIYRTLGQDYDERVLPSIVNEVLKAVVAQFNASQLITQREKVSRLIRENLVRRASKFNILLDDVSITYMTFSPEFTNAVEAKQIAQQDAQRAAFVVDKARQEKQGMVVRAQGEAKSAELIGEAIKKSRD-YVELKRLDTARDIAKILASSPNRVIL-DNEALLLN 298

[Close]

BLAST of Prohibitin vs. Ensembl Nematostella
Match: EDO49486 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG85])

HSP 1 Score: 379.793 bits (974), Expect = 3.964e-133
Identity = 176/245 (71.84%), Postives = 214/245 (87.35%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLP 935
            L+ V GGHRAVIFDR  GV+PDV+GEGTHFLIPW+Q+PII+DIRTRPRNVPV TGSKDLQ VNITLRILY+P+ ++LPKIY NLG D++ERVLPSIT EVLK VVAQFDA +LITQRE+VS KV E LT RAS+FGL+LDDISLTHLTFG EF++AVELKQVAQQ+AERARFLVE+AEQ+K AA+ISAEGD++ A LLA++F + GEG +EL++I+ SEEIA  +S+++N+ YLP  Q  L++LP
Sbjct:   27 LFNVDGGHRAVIFDRFQGVKPDVVGEGTHFLIPWVQRPIIFDIRTRPRNVPVTTGSKDLQNVNITLRILYRPQPQVLPKIYMNLGEDYDERVLPSITTEVLKAVVAQFDAGELITQREMVSQKVQEDLTERASSFGLVLDDISLTHLTFGKEFTEAVELKQVAQQDAERARFLVERAEQQKKAAVISAEGDARGAALLAQAFKEAGEGLVELRKIEASEEIAERMSRSRNVAYLPGGQKMLLNLP 271

[Close]

BLAST of Prohibitin vs. Ensembl Nematostella
Match: EDO42348 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1L7])

HSP 1 Score: 270.011 bits (689), Expect = 1.246e-89
Identity = 134/244 (54.92%), Postives = 182/244 (74.59%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISL 932
            +YTV GGHRA+IF RI GV+  V  EG HF IPW Q PIIYDIR+RPR +   TGSKDLQ VNI LR+L +P+A  LP +Y  LGLDF+ERVLPSI  EVLK+VVAQF+AS LIT R+ VS  +   L  RA +F ++LDD+S+T L+FG E++ A+E KQVAQQEA+RA+F+VEKA QE+   I+ AEG++QAA LL ++      G++ L++I+ +++I+R+++ ++N VYL D  G L++L
Sbjct:   40 VYTVDGGHRAIIFSRIGGVQDTVYTEGLHFRIPWFQYPIIYDIRSRPRKIISPTGSKDLQMVNIGLRVLARPEANKLPPMYRKLGLDFDERVLPSIMNEVLKSVVAQFNASQLITMRQQVSLLIRRQLMERARDFYIILDDVSITDLSFGKEYTSAIEAKQVAQQEAQRAQFIVEKAIQERQQKIVQAEGEAQAAKLLGEALKD-NPGYLRLRKIRAAQKISRVIAASQNPVYL-DSDGLLLNL 281

[Close]

BLAST of Prohibitin vs. Ensembl Medaka
Match: phb (prohibitin [Source:NCBI gene;Acc:101158276])

HSP 1 Score: 349.362 bits (895), Expect = 9.714e-121
Identity = 164/244 (67.21%), Postives = 204/244 (83.61%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISL 932
            LY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKP+I+D R+RPRNVPV TGSKDLQ VNITLRIL++P    LP+I+T++G D++ERVLPSIT EVLK VVA+FDA +LITQRELVS +V+E LT RA+ FGL+LDD+SLTHLTFG EF++AVE+KQVAQQEAERARF+VEKAEQ+K A IISAEGDSQAA L+A S    G+G +EL++++ +E+IA  L++++N+ YLP  QGTL  L
Sbjct:   26 LYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPVIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVTSQLPRIFTSIGEDYDERVLPSITTEVLKAVVARFDAGELITQRELVSRQVSEDLTERATTFGLILDDVSLTHLTFGKEFTEAVEMKQVAQQEAERARFVVEKAEQQKQATIISAEGDSQAALLIANSLMDAGDGLVELRKLEAAEDIAFQLARSRNVTYLPSGQGTLFQL 269

[Close]

BLAST of Prohibitin vs. Ensembl Medaka
Match: phb (prohibitin [Source:NCBI gene;Acc:101158276])

HSP 1 Score: 349.747 bits (896), Expect = 1.495e-120
Identity = 164/244 (67.21%), Postives = 204/244 (83.61%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISL 932
            LY V  GHRAVIFDR  GV+  V+GEGTHFLIPW+QKP+I+D R+RPRNVPV TGSKDLQ VNITLRIL++P    LP+I+T++G D++ERVLPSIT EVLK VVA+FDA +LITQRELVS +V+E LT RA+ FGL+LDD+SLTHLTFG EF++AVE+KQVAQQEAERARF+VEKAEQ+K A IISAEGDSQAA L+A S    G+G +EL++++ +E+IA  L++++N+ YLP  QGTL  L
Sbjct:   54 LYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPVIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVTSQLPRIFTSIGEDYDERVLPSITTEVLKAVVARFDAGELITQRELVSRQVSEDLTERATTFGLILDDVSLTHLTFGKEFTEAVEMKQVAQQEAERARFVVEKAEQQKQATIISAEGDSQAALLIANSLMDAGDGLVELRKLEAAEDIAFQLARSRNVTYLPSGQGTLFQL 297

[Close]

BLAST of Prohibitin vs. Ensembl Medaka
Match: phb2b (prohibitin 2 [Source:NCBI gene;Acc:101159337])

HSP 1 Score: 254.988 bits (650), Expect = 3.052e-83
Identity = 123/234 (52.56%), Postives = 176/234 (75.21%), Query Frame = 3

Query:  204 YTVPGGHRAVIFDRISGVRPD-VIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
            YTV GGHRA++F+RI G++ D ++ EG HF IPWIQ PIIYDIR +PR +   TGSKDLQ VNI +R+L +P A  LP +Y  LG D++ERVLPSI  EVLK+VVA+F+AS LITQR  VS  V   L  RA +F ++LDD+S+T L+F ++++ AVE KQVAQQEA+RA+F VEKA+Q++   II AEG+++AA +L ++  +   G+++L+RI+ ++ IA+ ++ ++N +YL
Sbjct:   49 YTVEGGHRAIVFNRIGGMQMDTILSEGLHFRIPWIQYPIIYDIRAKPRKISSLTGSKDLQMVNIAVRVLSRPLASNLPIMYQQLGKDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLVRRELYDRAKDFNIILDDVSITELSFSSQYTAAVEAKQVAQQEAQRAQFYVEKAKQDQRQKIIQAEGEAEAAKMLGQAVTK-NPGYLKLRRIRAAQNIAKTVAASQNRIYL 281

[Close]

BLAST of Prohibitin vs. Planmine SMEST
Match: SMESG000038397.1 (SMESG000038397.1)

HSP 1 Score: 518.85 bits (1335), Expect = 0.000e+0
Identity = 270/270 (100.00%), Postives = 270/270 (100.00%), Query Frame = 3

Query:  129 MAVFDLLAKFXXXXXXXXXXXXXXLYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLPA 938
            MAVFDLLAKFGVAVAVAGGVASSALYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLPA
Sbjct:    1 MAVFDLLAKFGVAVAVAGGVASSALYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYLPDKQGTLISLPA 270

[Close]

BLAST of Prohibitin vs. Planmine SMEST
Match: SMESG000021272.1 (SMESG000021272.1)

HSP 1 Score: 247.284 bits (630), Expect = 6.700e-81
Identity = 116/234 (49.57%), Postives = 173/234 (73.93%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
             YTV GG R++IF R  G++ ++  EG H  IP IQ PII+D+R+RPR +   TGSKDLQ VNI+LR+L +P    +P IY N+G D++E+VLPSI+ EVLK VVA+F+A  LITQRE VS  + ++L  RA +F +++DD+S+T L+F  ++S+AVE KQ++QQEA+RA+F V +A+QE+   I++AEG++QAA L+  +  Q   G+++L++I+ +E+IAR LS ++N  YL
Sbjct:    5 FYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAQDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSS-GYLKLRKIKAAEKIARTLSTSQNKAYL 237

[Close]

BLAST of Prohibitin vs. Planmine SMEST
Match: SMESG000021272.1 (SMESG000021272.1)

HSP 1 Score: 247.284 bits (630), Expect = 1.518e-80
Identity = 116/234 (49.57%), Postives = 173/234 (73.93%), Query Frame = 3

Query:  201 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 902
             YTV GG R++IF R  G++ ++  EG H  IP IQ PII+D+R+RPR +   TGSKDLQ VNI+LR+L +P    +P IY N+G D++E+VLPSI+ EVLK VVA+F+A  LITQRE VS  + ++L  RA +F +++DD+S+T L+F  ++S+AVE KQ++QQEA+RA+F V +A+QE+   I++AEG++QAA L+  +  Q   G+++L++I+ +E+IAR LS ++N  YL
Sbjct:   33 FYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAQDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSS-GYLKLRKIKAAEKIARTLSTSQNKAYL 265

The following BLAST results are available for this feature:

BLAST of Prohibitin vs. Ensembl Human
BLAST of Prohibitin vs. Ensembl Celegans
BLAST of Prohibitin vs. Ensembl Fly
BLAST of Prohibitin vs. Ensembl Zebrafish
BLAST of Prohibitin vs. Ensembl Xenopus
BLAST of Prohibitin vs. Ensembl Mouse
BLAST of Prohibitin vs. UniProt/SwissProt
BLAST of Prohibitin vs. TrEMBL
BLAST of Prohibitin vs. Ensembl Cavefish
BLAST of Prohibitin vs. Ensembl Sea Lamprey
BLAST of Prohibitin vs. Ensembl Yeast
BLAST of Prohibitin vs. Ensembl Nematostella
BLAST of Prohibitin vs. Ensembl Medaka
BLAST of Prohibitin vs. Planmine SMEST

BLAST of Prohibitin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PHB	6.329e-123	67.42	prohibitin [Source:HGNC Symbol;Acc:HGNC:8912]	[more]
PHB	6.329e-123	67.42	prohibitin [Source:HGNC Symbol;Acc:HGNC:8912]	[more]
PHB	6.329e-123	67.42	prohibitin [Source:HGNC Symbol;Acc:HGNC:8912]	[more]
PHB	2.465e-113	69.01	prohibitin [Source:HGNC Symbol;Acc:HGNC:8912]	[more]
PHB	3.589e-102	72.64	prohibitin [Source:HGNC Symbol;Acc:HGNC:8912]	[more]

BLAST of Prohibitin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
phb-1	2.219e-111	65.57	Mitochondrial prohibitin complex protein 1 [Sourc...	[more]
phb-2	9.178e-82	52.77	Mitochondrial prohibitin complex protein 2 [Sourc...	[more]
phb-2	9.178e-82	52.77	Mitochondrial prohibitin complex protein 2 [Sourc...	[more]

BLAST of Prohibitin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
l(2)37Cc	2.072e-125	68.29	gene:FBgn0002031 transcript:FBtr0081164	[more]
l(2)37Cc	2.072e-125	68.29	gene:FBgn0002031 transcript:FBtr0081165	[more]
l(2)37Cc	2.072e-125	68.29	gene:FBgn0002031 transcript:FBtr0346428	[more]
Phb2	6.704e-85	51.28	gene:FBgn0010551 transcript:FBtr0086614	[more]
Phb2	6.704e-85	51.28	gene:FBgn0010551 transcript:FBtr0086615	[more]

BLAST of Prohibitin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
phb	5.917e-125	69.39	prohibitin [Source:ZFIN;Acc:ZDB-GENE-030131-6577]	[more]
phb2b	1.508e-83	54.70	prohibitin 2b [Source:ZFIN;Acc:ZDB-GENE-040718-430...	[more]
phb2b	1.508e-83	54.70	prohibitin 2b [Source:ZFIN;Acc:ZDB-GENE-040718-430...	[more]
phb2b	1.508e-83	54.70	prohibitin 2b [Source:ZFIN;Acc:ZDB-GENE-040718-430...	[more]
phb2a	2.590e-82	53.42	prohibitin 2a [Source:ZFIN;Acc:ZDB-GENE-030131-314...	[more]

BLAST of Prohibitin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4


Match Name	E-value	Identity	Description
phb	6.871e-121	65.17	prohibitin [Source:NCBI gene;Acc:394635]	[more]
cgref1	1.085e-84	53.19	cell growth regulator with EF-hand domain 1 [Sourc...	[more]
cgref1	1.085e-84	53.19	cell growth regulator with EF-hand domain 1 [Sourc...	[more]
cgref1	1.088e-84	53.19	cell growth regulator with EF-hand domain 1 [Sourc...	[more]

BLAST of Prohibitin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Phb	9.514e-124	67.79	prohibitin [Source:MGI Symbol;Acc:MGI:97572]	[more]
Phb	1.262e-97	72.41	prohibitin [Source:MGI Symbol;Acc:MGI:97572]	[more]
Phb2	9.405e-88	54.04	prohibitin 2 [Source:MGI Symbol;Acc:MGI:102520]	[more]
Phb2	1.909e-39	63.37	prohibitin 2 [Source:MGI Symbol;Acc:MGI:102520]	[more]
Phb2	8.784e-33	38.12	prohibitin 2 [Source:MGI Symbol;Acc:MGI:102520]	[more]

BLAST of Prohibitin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P24156\|L2CC_DROME	2.077e-124	68.29	Protein l(2)37Cc OS=Drosophila melanogaster OX=722...	[more]
sp\|P67779\|PHB_RAT	6.655e-123	67.79	Prohibitin OS=Rattus norvegicus OX=10116 GN=Phb PE...	[more]
sp\|P67778\|PHB_MOUSE	6.655e-123	67.79	Prohibitin OS=Mus musculus OX=10090 GN=Phb PE=1 SV...	[more]
sp\|P84173\|PHB_CHICK	1.112e-122	66.29	Prohibitin OS=Gallus gallus OX=9031 GN=PHB PE=1 SV...	[more]
sp\|P35232\|PHB_HUMAN	3.039e-122	67.42	Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=...	[more]

BLAST of Prohibitin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A430QDG4	3.766e-133	75.61	Prohibitin OS=Schistosoma bovis OX=6184 GN=DC041_0...	[more]
A0A5K4FC32	5.300e-133	75.61	Uncharacterized protein OS=Schistosoma mansoni OX=...	[more]
A0A0V0J2R0	7.151e-133	74.69	Prohibitin (Fragment) OS=Schistocephalus solidus O...	[more]
A0A183TP29	8.831e-133	74.69	Prohibitin OS=Schistocephalus solidus OX=70667 GN=...	[more]
Q5DE25	5.155e-132	75.20	Prohibitin OS=Schistosoma japonicum OX=6182 PE=2 S...	[more]

BLAST of Prohibitin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
phb	1.331e-123	68.57	prohibitin [Source:NCBI gene;Acc:103031128]	[more]
phb2a	2.675e-83	53.19	prohibitin-2-like [Source:NCBI gene;Acc:103035142]	[more]
phb2b	6.557e-82	52.14	prohibitin-2-like [Source:NCBI gene;Acc:103047478]	[more]
phb2a	3.668e-80	54.19	prohibitin-2-like [Source:NCBI gene;Acc:103035142]	[more]
phb2b	1.103e-78	52.30	prohibitin-2-like [Source:NCBI gene;Acc:103047478]	[more]

BLAST of Prohibitin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
phb	1.805e-119	65.98	prohibitin [Source:ZFIN;Acc:ZDB-GENE-030131-6577]	[more]
ENSPMAT00000006512.1	7.992e-47	60.83	pep scaffold:Pmarinus_7.0:GL479067:257:4164:-1 gen...	[more]

BLAST of Prohibitin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
PHB1	4.053e-106	56.30	Subunit of the prohibitin complex (Phb1p-Phb2p); p...	[more]
PHB2	3.688e-86	50.62	Subunit of the prohibitin complex (Phb1p-Phb2p); p...	[more]

BLAST of Prohibitin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO49486	3.964e-133	71.84	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42348	1.246e-89	54.92	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Prohibitin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
phb	9.714e-121	67.21	prohibitin [Source:NCBI gene;Acc:101158276]	[more]
phb	1.495e-120	67.21	prohibitin [Source:NCBI gene;Acc:101158276]	[more]
phb2b	3.052e-83	52.56	prohibitin 2 [Source:NCBI gene;Acc:101159337]	[more]

BLAST of Prohibitin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000038397.1	0.000e+0	100.00	SMESG000038397.1	[more]
SMESG000021272.1	6.700e-81	49.57	SMESG000021272.1	[more]
SMESG000021272.1	1.518e-80	49.57	SMESG000021272.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30003249 ID=SMED30003249|Name=Prohibitin|organism=Schmidtea mediterranea sexual|type=transcript|length=1005bp
ATTTTTCTACATATTTTTATAATATTTTAATATAATAAATTAAAGGCATT
TTTATTTTTTAATGAATTATGTTAGTTTCTTTAAATGAACTAAATTGGCT
CATTGTTTGAAATTATAAACCGTGATATATGGCAGTCTTTGATTTATTAG
CAAAATTTGGTGTTGCAGTTGCTGTTGCCGGGGGTGTCGCTAGTTCAGCA
TTATATACTGTTCCCGGTGGTCATAGAGCTGTTATTTTTGATCGTATTAG
CGGTGTTCGACCAGATGTTATTGGCGAAGGTACACATTTCCTGATCCCAT
GGATACAAAAGCCAATTATTTATGACATTCGAACTCGCCCAAGAAATGTT
CCAGTTAATACTGGTTCCAAGGATTTACAGAAAGTGAACATAACTCTTAG
AATTTTGTATAAACCTAAAGCTGAAATGTTACCGAAAATCTACACAAATT
TAGGTTTAGATTTTGAAGAAAGAGTTCTTCCATCGATAACATATGAAGTT
TTGAAAACAGTTGTTGCTCAATTTGATGCCAGTGACTTAATCACTCAGAG
AGAATTAGTTAGTAATAAAGTTAATGAAATGCTCACATCTAGGGCTTCTA
ATTTTGGATTAATGCTTGATGATATTTCATTGACTCATTTGACTTTTGGA
ACTGAATTTTCCGATGCCGTCGAATTGAAACAAGTCGCTCAGCAAGAAGC
AGAAAGGGCGAGATTTTTGGTTGAAAAGGCTGAGCAAGAGAAACTAGCAG
CTATTATTAGTGCTGAAGGTGACTCACAAGCTGCCAATTTGCTCGCCAAG
TCATTCAATCAATGCGGCGAAGGATTTATCGAACTGCAAAGAATTCAAAC
CTCTGAAGAAATTGCGCGCTTATTGTCAAAAAATAAAAACATTGTCTACT
TGCCCGATAAACAGGGAACCTTGATCAGTCTCCCTGCATAATGTCTTTAG
TTGCTGTGTCGTAATTATAGAATTAGAAATTTGTCTTTATTGAAAAAAAA
AGATC

protein sequence of SMED30003249-orf-1

>SMED30003249-orf-1 ID=SMED30003249-orf-1|Name=SMED30003249-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=271bp
MAVFDLLAKFGVAVAVAGGVASSALYTVPGGHRAVIFDRISGVRPDVIGE
GTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEM
LPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNE
MLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEK
AEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLS
KNKNIVYLPDKQGTLISLPA*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000039	gamma neoblast
PLANA:0000429	neoblast
PLANA:0002013	Category 1 cell
PLANA:0002032	epidermal cell
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036013	Band_7/SPFH_dom_sf
IPR000163	Prohibitin
IPR001107	Band_7

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 184..204
None	No IPR available	GENE3D	G3DSA:3.30.479.30		coord: 53..187 e-value: 4.3E-5 score: 25.5
None	No IPR available	PANTHER	PTHR23222:SF14	PROHIBITIN	coord: 3..269
IPR000163	Prohibitin	PRINTS	PR00679	PROHIBITIN	coord: 180..203 score: 80.13 coord: 203..219 score: 54.75 coord: 68..84 score: 63.35 coord: 109..127 score: 69.23 coord: 86..105 score: 55.77 coord: 132..148 score: 59.73 coord: 155..174 score: 58.46
IPR000163	Prohibitin	PANTHER	PTHR23222	PROHIBITIN	coord: 3..269
IPR000163	Prohibitin	CDD	cd03401	SPFH_prohibitin	coord: 25..219 e-value: 1.11031E-93 score: 272.465
IPR001107	Band 7 domain	SMART	SM00244	PHB_4	coord: 23..185 e-value: 7.0E-42 score: 155.1
IPR001107	Band 7 domain	PFAM	PF01145	Band_7	coord: 27..204 e-value: 4.8E-24 score: 85.3
IPR036013	Band 7/SPFH domain superfamily	SUPERFAMILY	SSF117892	Band 7/SPFH domain	coord: 56..192