Structural maintenance of chromosomes protein

Overview
NameStructural maintenance of chromosomes protein
Smed IDSMED30003246
Length (bp)2958
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Structural maintenance of chromosomes protein (SMED30003246) t-SNE clustered cells

Violin plots show distribution of expression levels for Structural maintenance of chromosomes protein (SMED30003246) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Structural maintenance of chromosomes protein (SMED30003246) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Structural maintenance of chromosomes protein (SMED30003246) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30003246

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30003246h1SMcG0010938 SmedASXL_016045SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30003246h1SMcG0010938 SmedASXL_016045SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30003246h1SMcG0010938 dd_Smed_v4_5865_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003246h1SMcG0010938 dd_Smed_v4_5865_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30003246h1SMcG0010938 dd_Smed_v4_5865_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30003246h1SMcG0010938 dd_Smed_v4_5865_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003246h1SMcG0010938 dd_Smed_v4_5865_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003246h1SMcG0010938 dd_Smed_v4_5865_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Human
Match: SMC4 (structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013])

HSP 1 Score: 338.576 bits (867), Expect = 1.089e-122
Identity = 224/590 (37.97%), Postives = 329/590 (55.76%), Query Frame = 3 
Query:  936 VKGELIEVTGSMTGGGSRQVRGKICTD-VAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEE---DNEKELNI----LEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKN-HQITYQD--MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            ++G++IE +G+MTGGGS+ ++G++ +  V +I                 +E+  ++ E +L +   +   + E+   L+ R+   + S+  ++N L+      +   + E+ LN+    LE  + A  PD K   LLE  + + K +Y+  + +   ++ EV ++   I  +   KL   + +LD I++Q  E    + K  +A+K A++   K  + +     E    E+   ++ A LK LE KA + +       E +  + K       E+  I EN    +   + I    E+    + +   +I+    +I K++ +P+ +   E+                              + V S E+L   KN   IT Q   +E + ++ KPNL AI EY+ KEELY+ R AEL ++T  RD  R   E +++QR  EF AGF +IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E++D LIGI K +N TK+  +N K +
Sbjct:  740 LQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEI-----------------SEEEVNKMESQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVKELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEE------------------------------ISVLSPEDLEAIKNPDSITNQIALLEARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFYIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIYKTYNITKSVAVNPKEI 1282

HSP 2 Score: 124.02 bits (310), Expect = 1.089e-122
Identity = 61/144 (42.36%), Postives = 92/144 (63.89%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            KVL  ++ ++ SG++ G+ GRLG+L AI  KYDVA+S+ C  LD I+ + I+ AQ+CV  +K   I  +TFIGL+K+  W KK  +      N PR FDL+ + +   R   YFA RD L+A+N+++A R   Q+  ++R+VTL
Sbjct:  598 KVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKRQNIGVATFIGLDKMAVWAKKMTE-IQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADNLDQATRVAYQKDRRWRVVTL 740
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Human
Match: SMC4 (structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013])

HSP 1 Score: 338.576 bits (867), Expect = 1.089e-122
Identity = 224/590 (37.97%), Postives = 329/590 (55.76%), Query Frame = 3 
Query:  936 VKGELIEVTGSMTGGGSRQVRGKICTD-VAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEE---DNEKELNI----LEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKN-HQITYQD--MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            ++G++IE +G+MTGGGS+ ++G++ +  V +I                 +E+  ++ E +L +   +   + E+   L+ R+   + S+  ++N L+      +   + E+ LN+    LE  + A  PD K   LLE  + + K +Y+  + +   ++ EV ++   I  +   KL   + +LD I++Q  E    + K  +A+K A++   K  + +     E    E+   ++ A LK LE KA + +       E +  + K       E+  I EN    +   + I    E+    + +   +I+    +I K++ +P+ +   E+                              + V S E+L   KN   IT Q   +E + ++ KPNL AI EY+ KEELY+ R AEL ++T  RD  R   E +++QR  EF AGF +IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E++D LIGI K +N TK+  +N K +
Sbjct:  740 LQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEI-----------------SEEEVNKMESQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVKELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEE------------------------------ISVLSPEDLEAIKNPDSITNQIALLEARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFYIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIYKTYNITKSVAVNPKEI 1282

HSP 2 Score: 124.02 bits (310), Expect = 1.089e-122
Identity = 61/144 (42.36%), Postives = 92/144 (63.89%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            KVL  ++ ++ SG++ G+ GRLG+L AI  KYDVA+S+ C  LD I+ + I+ AQ+CV  +K   I  +TFIGL+K+  W KK  +      N PR FDL+ + +   R   YFA RD L+A+N+++A R   Q+  ++R+VTL
Sbjct:  598 KVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKRQNIGVATFIGLDKMAVWAKKMTE-IQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADNLDQATRVAYQKDRRWRVVTL 740
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Human
Match: SMC4 (structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013])

HSP 1 Score: 338.191 bits (866), Expect = 1.445e-122
Identity = 224/590 (37.97%), Postives = 329/590 (55.76%), Query Frame = 3 
Query:  936 VKGELIEVTGSMTGGGSRQVRGKICTD-VAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEE---DNEKELNI----LEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKN-HQITYQD--MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            ++G++IE +G+MTGGGS+ ++G++ +  V +I                 +E+  ++ E +L +   +   + E+   L+ R+   + S+  ++N L+      +   + E+ LN+    LE  + A  PD K   LLE  + + K +Y+  + +   ++ EV ++   I  +   KL   + +LD I++Q  E    + K  +A+K A++   K  + +     E    E+   ++ A LK LE KA + +       E +  + K       E+  I EN    +   + I    E+    + +   +I+    +I K++ +P+ +   E+                              + V S E+L   KN   IT Q   +E + ++ KPNL AI EY+ KEELY+ R AEL ++T  RD  R   E +++QR  EF AGF +IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E++D LIGI K +N TK+  +N K +
Sbjct:  715 LQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEI-----------------SEEEVNKMESQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVKELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEE------------------------------ISVLSPEDLEAIKNPDSITNQIALLEARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFYIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIYKTYNITKSVAVNPKEI 1257

HSP 2 Score: 124.02 bits (310), Expect = 1.445e-122
Identity = 61/144 (42.36%), Postives = 92/144 (63.89%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            KVL  ++ ++ SG++ G+ GRLG+L AI  KYDVA+S+ C  LD I+ + I+ AQ+CV  +K   I  +TFIGL+K+  W KK  +      N PR FDL+ + +   R   YFA RD L+A+N+++A R   Q+  ++R+VTL
Sbjct:  573 KVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKRQNIGVATFIGLDKMAVWAKKMTE-IQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADNLDQATRVAYQKDRRWRVVTL 715
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Human
Match: SMC4 (structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013])

HSP 1 Score: 305.834 bits (782), Expect = 9.202e-113
Identity = 212/597 (35.51%), Postives = 312/597 (52.26%), Query Frame = 3 
Query:  936 VKGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEE---DNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKD------------DIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKN-HQITYQD--MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            ++G++IE +G+MTGGGS+ ++G                R   +   + +E+  ++ E +L +   +   + E+   L+ R+   + S+  ++N L+      +   + E+ LN+   +L+AN        +L TA    K+K  +++V                           K+  DA+     EK G   K+   VK+      ++ N    L  ++ K ++  K++D     + K                           V I   + NLQK++   ++  ++ ++ +  VD +   ++ ++D            +I K++ +P+ +   E+                              + V S E+L   KN   IT Q   +E + ++ KPNL AI EY+ KEELY+ R AEL ++T  RD  R   E +++QR  EF AGF +IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E++D LIGI K +N TK+  +N K +
Sbjct:  740 LQGQIIEQSGTMTGGGSKVMKG----------------RMGSSLVIEISEEEVNKMESQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVKELEAN--------VLATAPDKKKQKLLEENV------------------------SAFKTEYDAV----AEKAG---KVEAEVKRLHNTIVEINN--HKLKAQQDKLDKINKQLDECASAITK-------------------------AQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEISKISLHPIEDNPIEE------------------------------ISVLSPEDLEAIKNPDSITNQIALLEARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFYIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIYKTYNITKSVAVNPKEI 1224

HSP 2 Score: 124.02 bits (310), Expect = 9.202e-113
Identity = 61/144 (42.36%), Postives = 92/144 (63.89%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            KVL  ++ ++ SG++ G+ GRLG+L AI  KYDVA+S+ C  LD I+ + I+ AQ+CV  +K   I  +TFIGL+K+  W KK  +      N PR FDL+ + +   R   YFA RD L+A+N+++A R   Q+  ++R+VTL
Sbjct:  598 KVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKRQNIGVATFIGLDKMAVWAKKMTE-IQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADNLDQATRVAYQKDRRWRVVTL 740
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Human
Match: SMC1A (structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111])

HSP 1 Score: 132.494 bits (332), Expect = 1.141e-30
Identity = 71/198 (35.86%), Postives = 119/198 (60.10%), Query Frame = 3 
Query: 2061 MEDKLNKQK--------PNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAE--LELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDR-TKNAQFIIISLRNNMYELADCLIGI 2621
            ++ KLN+Q+        PN+ A+E+     + +   + E     +   + +   E++K++R   F A F  + T + E+Y+ ++    A+  L   +  +P+ +GI ++   P K ++ + NLSGGEKT+++LAL+FA+H +KP PF+V+DEIDAALD  N+  VANYIK++ T N Q I+ISL+   Y  A+ LIG+
Sbjct:  984 LQQKLNEQQSVLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKEQSTCNFQAIVISLKEEFYTKAESLIGV 1181
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Celegans
Match: dpy-27 (Chromosome condensation protein dpy-27 [Source:UniProtKB/Swiss-Prot;Acc:P48996])

HSP 1 Score: 195.667 bits (496), Expect = 9.453e-51
Identity = 104/211 (49.29%), Postives = 139/211 (65.88%), Query Frame = 3 
Query: 2067 DKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQ---QRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVD---SLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIK--DRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAVD 2675
            DK  ++  N   + +Y M   L M    E+T   +F D+    R++L +++  R  EF+     + T  + +YQ+IT GGDA L+ V+   S DPF  GI FSVRP KKSWK I NLSGGEKTL+SL  VFA+HH++PTP YVMDEIDAALD  NVS++ANYIK  +RT+NAQFIIISLRN M+E+ + L+GI K    T   +++  AV+
Sbjct: 1133 DKFRREFDN-KGVRDYAMIVSLLM---NEVTSAKKFSDKLKAHREKLNELRMARFNEFSEALAFLGTTTQMLYQLITNGGDASLKFVEEGKSTDPFDGGIKFSVRPAKKSWKLIENLSGGEKTLASLCFVFAMHHYRPTPLYVMDEIDAALDLNNVSLIANYIKHSERTRNAQFIIISLRNQMFEVGNRLLGIYKIDGKTYNIMVDPIAVE 1339

HSP 2 Score: 59.6918 bits (143), Expect = 1.185e-9
Identity = 42/154 (27.27%), Postives = 78/154 (50.65%), Query Frame = 2 
Query:  461 HKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTA-CTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKAND---KFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEARQTNQR-AMKYRIVTLNVTFV 907
            H+  + L   + +G   G  GRLG+L +I  K+D A+ST    +LD  + +  ++ +  +     +K+ R+TF+ L+ +        D   KF A     R FD +   N + R   YF   D+L+ +++EEA + +++   ++R  TLN + +
Sbjct:  605 HQATAKLHELKEAGLFPGFKGRLGDLASIPIKFDTAISTVFFAQLDYHVVQTSDECRIGIGFCHEYKLPRTTFVFLDHLKDTDTSGMDSTMKFPAE----RLFDKIHCVNPEIRREFYFLIHDILVVDSLEEATRIDKKYPGRHRYCTLNGSIL 754

HSP 3 Score: 23.0978 bits (48), Expect = 1.185e-9
Identity = 9/27 (33.33%), Postives = 17/27 (62.96%), Query Frame = 3 
Query:  936 VKGELIEVTGSMTGGGSRQVRGKICTD 1016
            + G ++  +G++TGGG +   G+I  D
Sbjct:  749 LNGSILNRSGALTGGG-KPTTGRIRND 774
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Celegans
Match: him-1 (Structural maintenance of chromosomes protein 1 [Source:UniProtKB/Swiss-Prot;Acc:O01789])

HSP 1 Score: 122.865 bits (307), Expect = 4.037e-28
Identity = 62/158 (39.24%), Postives = 99/158 (62.66%), Query Frame = 3 
Query: 2187 RDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELEL-VDSLD-PFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTK-NAQFIIISLRNNMYELADCLIGINKPFNFTKTC 2651
            R Q EK+K  R++ F   F+ +   + ++Y+ ++    A+  L  D+++ P+ +GI ++   P K ++ + NLSGGEKT+++LAL+FA+H   P PF+V+DEIDAALD  N+  VA+YI +  + + Q I+ISL+   Y  AD LIGI   F +   C
Sbjct: 1076 RQQFEKVKTDRYRRFQDFFDPVANTIDDIYKQLSRNTSAQAFLGADNMEEPYLDGIQYNCVAPGKRFRPMDNLSGGEKTIAALALLFAVHGRNPAPFFVLDEIDAALDNTNIGKVASYICESAREHMQIIVISLKEEFYNKADSLIGI---FPYPAAC 1230
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Celegans
Match: him-1 (Structural maintenance of chromosomes protein 1 [Source:UniProtKB/Swiss-Prot;Acc:O01789])

HSP 1 Score: 100.908 bits (250), Expect = 1.086e-24
Identity = 50/109 (45.87%), Postives = 73/109 (66.97%), Query Frame = 3 
Query: 2328 DPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTK-NAQFIIISLRNNMYELADCLIGINKPFNFTKTC 2651
            +P+ +GI ++   P K ++ + NLSGGEKT+++LAL+FA+H   P PF+V+DEIDAALD  N+  VA+YI +  + + Q I+ISL+   Y  AD LIGI   F +   C
Sbjct:    3 EPYLDGIQYNCVAPGKRFRPMDNLSGGEKTIAALALLFAVHGRNPAPFFVLDEIDAALDNTNIGKVASYICESAREHMQIIVISLKEEFYNKADSLIGI---FPYPAAC 108
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Celegans
Match: mix-1 (Mitotic chromosome and X-chromosome-associated protein mix-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09591])

HSP 1 Score: 74.7146 bits (182), Expect = 2.978e-13
Identity = 32/72 (44.44%), Postives = 49/72 (68.06%), Query Frame = 3 
Query: 2397 LSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCL 2612
            LSGG+++L +L+L+ A+  FKP P Y++DE+DAALD  + + +   IK    + QFII+SL+  M+  AD L
Sbjct: 1100 LSGGQRSLVALSLILAMLKFKPAPLYILDEVDAALDLSHTANIGMMIKTHFHHNQFIIVSLKQGMFSNADVL 1171
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Celegans
Match: smc-3 (Structural maintenance of chromosomes protein 3 [Source:UniProtKB/Swiss-Prot;Acc:B2FDA8])

HSP 1 Score: 72.0182 bits (175), Expect = 4.051e-13
Identity = 30/80 (37.50%), Postives = 51/80 (63.75%), Query Frame = 3 
Query: 2382 KNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGI 2621
            + ++ LSGG+K+L +LA++F++    P PFY+ DEIDAALD ++   VA+ I+  +  AQF+  + R  +   A+   G+
Sbjct:  222 REMTQLSGGQKSLVALAIIFSIQKCDPAPFYLFDEIDAALDAQHRKSVADMIQSLSDQAQFVTTTFRPELLATAEKFYGV 301
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Fly
Match: glu (gene:FBgn0015391 transcript:FBtr0080935)

HSP 1 Score: 275.789 bits (704), Expect = 1.310e-76
Identity = 126/199 (63.32%), Postives = 165/199 (82.91%), Query Frame = 3 
Query: 2061 MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLL 2657
            +E+ L  +KPNL+ I+E+  K  +Y+ R   L ++T  R++ RD+ E+++++R++EF  GF++IT KLKEMYQMIT+GGDAELELVDS+DPF+EG+ F+VRPPKKSWK ISNLSGGEKTLSSLALVFALH++KP+P Y MDEIDAALDFKNVSIV +YIK+RTKNAQFII+SLR NM+ELA+ L+GI K  + T +  +
Sbjct: 1094 LEEDLKTKKPNLSCIKEFNEKRLVYLDRVRVLEDITSKRNEMRDKYEEVRKRRYKEFMDGFSIITRKLKEMYQMITLGGDAELELVDSMDPFTEGVNFTVRPPKKSWKYISNLSGGEKTLSSLALVFALHYYKPSPLYFMDEIDAALDFKNVSIVGHYIKERTKNAQFIIVSLRVNMFELANFLVGIYKVSDCTDSITM 1292

HSP 2 Score: 125.176 bits (313), Expect = 1.163e-28
Identity = 56/150 (37.33%), Postives = 96/150 (64.00%), Query Frame = 2 
Query:  443 QSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEARQTNQRAMKYRIVTL 892
            Q++ + +KVL FLM  +  GK+ G++GRLG+L  I  KYD+A+STAC RLD+I+T++   A   +  +K + + R+TFI L+K+    ++AN +     N+PR +DL+ + ++  R   YFA R+ L+ +++E+  +      +YR+VTL
Sbjct:  596 QAQRSNNKVLDFLMRMKMEGKIPGILGRLGDLGGIDAKYDIAISTACGRLDNIVTDNYETASAAIGALKEYNVGRATFITLDKIEHHRREANSRINTPENVPRLYDLVKVEDDRVRTAFYFALRNTLVCDDLEQGTRIAYGRERYRVVTL 745
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Fly
Match: SMC1 (gene:FBgn0040283 transcript:FBtr0084541)

HSP 1 Score: 125.946 bits (315), Expect = 6.818e-29
Identity = 69/202 (34.16%), Postives = 115/202 (56.93%), Query Frame = 3 
Query: 2034 KNHQITYQDMEDKLNK----QKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELV--DSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGI 2621
            K H++  +D++ KL+     Q PN+ A+++     E       E     +   + +   E++K +R   F A    I+  +  +Y+ +     A+  +   +  +P+ +GI ++   P K ++ ++NLSGGEKT+++LAL+F+ H F P PF+V+DEIDAALD  N+  VA+YI+D T N Q I+ISL+   Y  AD L+GI
Sbjct: 1014 KTHEMLQKDLQSKLDVLERIQTPNMKALQKLDAVTEKVQSTNEEFENARKKAKRAKAAFERVKNERSSRFVACCQHISDAIDGIYKKLARNEAAQAYIGPDNPEEPYLDGINYNCVAPGKRFQPMNNLSGGEKTIAALALLFSTHSFHPAPFFVLDEIDAALDNTNIGKVASYIRDHTTNLQTIVISLKEEFYGHADALVGI 1215
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Fly
Match: SMC3 (gene:FBgn0015615 transcript:FBtr0074290)

HSP 1 Score: 80.1073 bits (196), Expect = 7.361e-15
Identity = 52/148 (35.14%), Postives = 75/148 (50.68%), Query Frame = 3 
Query: 2211 RQRHQEFT----------AGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSE-GILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGI 2621
            RQ  Q FT          AGF ++ TK  E        GD   + V++ D F+  GI  S    +   + ++ LSGG+K+L +LAL+F++    P PFY+ DEID ALD  +   VAN I + +  AQFI  + R  + E A    G+
Sbjct: 1033 RQVAQNFTKVFKKLVPMGAGFLILKTKDNE--------GDEMEKEVENSDAFTGIGIRVSFTGVEAEMREMNQLSGGQKSLVALALIFSIQKCDPAPFYLFDEIDQALDAMHRKAVANMIHELSDTAQFITTTFRPELLENAHKFYGV 1172
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Fly
Match: SMC2 (gene:FBgn0027783 transcript:FBtr0087461)

HSP 1 Score: 78.5666 bits (192), Expect = 2.063e-14
Identity = 32/80 (40.00%), Postives = 54/80 (67.50%), Query Frame = 3 
Query: 2379 WK-NISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLI 2615
            WK ++  LSGG+K+L +L+LV A+  F P P Y++DE+DAALD  +   + + +K    N+QF+I+SL++ ++  A+ L 
Sbjct: 1076 WKESLGELSGGQKSLVALSLVLAMLKFSPAPLYILDEVDAALDMSHTQNIGSMLKQHFTNSQFLIVSLKDGLFNHANVLF 1155
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Zebrafish
Match: smc4 (structural maintenance of chromosomes 4 [Source:ZFIN;Acc:ZDB-GENE-020419-21])

HSP 1 Score: 348.591 bits (893), Expect = 1.195e-127
Identity = 222/595 (37.31%), Postives = 329/595 (55.29%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGK----ICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEED-NEKELNI------LEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE  G+MTGGG R ++G+    +C DV                    T++  D+ E  LN  + Q+ +  ++   L+ ++   +    +++N L+      +   E+EL++      LE  + A  PD      +E ++++ +K +E  S +   ++ EV ++   I  +   KL   + +LD I+ Q  + +  + K  +A+K A +   K  + +  L  E +++E+  +E+   LK LE++AG+ +  YQ+  E +  +         EI  + E     +   + +    E     + +   +I+  + +  KL  + + +GV  +       D + + G+ ++                 NE  L           +ED+    KPNL AI E++ KEELY+ R AEL ++T  RD  +   E +++QR  EF AGFN+IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHHFKPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E+AD LIGI K  N TK   +N K +
Sbjct:  734 WRVVTLQGQIIEQAGTMTGGGGRVMKGRMGSSVCADV--------------------TQEQLDKMESALNKEVTQLQDCQKRKNQLEEKVHKARCELRDMKNTLEKYTATIQSLTEQELHLKPQIKDLEANVIAAAPDKAKQKQMEKSLEAYRKDFEAASNKAGKVEAEVKRLHTLIVDINSHKLKAQQDKLDQINTQLDQCSSAVTKAQVAIKTAGRNLKKSEDGVSRLEQEISENEKLMEELTEQLKKLEEQAGEIMQSYQQAEEALPEVQDQHRAVVQEIKALQEQEHALQKESLSVRLKVEHIDTAITECHNKIKHWQKEASKLCLHHI-DGVPAEELPALNPDQLQDIGNPDVIK---------------NEIAL-----------LEDRCANMKPNLGAIAEFKKKEELYLQRVAELDDITTQRDSFKRGCEDLRKQRLHEFMAGFNIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIYNLSGGEKTLSSLALVFALHHFKPTPLYFMDEIDAALDFKNVSIVACYIYEQTKNAQFIIISLRNNMFEMADRLIGIYKTHNTTKNVAINPKTI 1281

HSP 2 Score: 130.183 bits (326), Expect = 1.195e-127
Identity = 64/144 (44.44%), Postives = 95/144 (65.97%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            KVL  LM Q+ SGK+ G++GRLG+L AI  KYDVA+S++C  LD+I+ + I+ AQKCV  +K   I  +TFIGL+K+  W +++        NIPR FD++ + +   R   YFA RD L+A ++E+A R   Q+  ++R+VTL
Sbjct:  597 KVLDTLMQQKRSGKIPGILGRLGDLGAIDEKYDVAISSSCGSLDNILVDTIDTAQKCVTFLKAQNIGVATFIGLDKMKVW-QQSMGSISTPENIPRLFDMVRVKDESVRPAFYFALRDTLVAKDLEQATRVAFQKDKRWRVVTL 739
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Zebrafish
Match: smc1a (structural maintenance of chromosomes 1A [Source:ZFIN;Acc:ZDB-GENE-090506-9])

HSP 1 Score: 134.806 bits (338), Expect = 1.547e-31
Identity = 71/198 (35.86%), Postives = 120/198 (60.61%), Query Frame = 3 
Query: 2061 MEDKLNKQK--------PNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAE--LELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRT-KNAQFIIISLRNNMYELADCLIGI 2621
            ++ +LN+Q+        PN+ A+E+     + +   + E     +   + +   E++K++R   F A F  + T + E+Y+ ++    A+  L   +  +P+ +GI ++   P K ++ + NLSGGEKT+++LAL+FA+H +KP PF+V+DEIDAALD  N+  VANYIKD++ +N Q I+ISL+   Y  AD LIG+
Sbjct: 1006 LQQRLNEQQSILQRISAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKDQSVQNFQAIVISLKEEFYTKADSLIGV 1203
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Zebrafish
Match: smc1al (structural maintenance of chromosomes 1A, like [Source:ZFIN;Acc:ZDB-GENE-040426-57])

HSP 1 Score: 134.035 bits (336), Expect = 2.377e-31
Identity = 71/198 (35.86%), Postives = 120/198 (60.61%), Query Frame = 3 
Query: 2061 MEDKLNKQK--------PNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAE--LELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRT-KNAQFIIISLRNNMYELADCLIGI 2621
            ++ +LN+Q+        PN+ A+E+     + +   + E     +   + +   E++K++R   F A F  + T + E+Y+ ++    A+  L   +  +P+ +GI ++   P K ++ + NLSGGEKT+++LAL+FA+H +KP PF+V+DEIDAALD  N+  VANYIKD++ +N Q I+ISL+   Y  AD LIG+
Sbjct: 1007 LQQRLNEQQSILQRISAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFHACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKDQSVQNFQAIVISLKEEFYTKADSLIGV 1204
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Zebrafish
Match: smc1al (structural maintenance of chromosomes 1A, like [Source:ZFIN;Acc:ZDB-GENE-040426-57])

HSP 1 Score: 133.65 bits (335), Expect = 3.114e-31
Identity = 71/198 (35.86%), Postives = 120/198 (60.61%), Query Frame = 3 
Query: 2061 MEDKLNKQK--------PNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELV--DSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRT-KNAQFIIISLRNNMYELADCLIGI 2621
            ++ +LN+Q+        PN+ A+E+     + +   + E     +   + +   E++K++R   F A F  + T + E+Y+ ++    A+  L   +  +P+ +GI ++   P K ++ + NLSGGEKT+++LAL+FA+H +KP PF+V+DEIDAALD  N+  VANYIKD++ +N Q I+ISL+   Y  AD LIG+
Sbjct: 1025 LQQRLNEQQSILQRISAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFHACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKDQSVQNFQAIVISLKEEFYTKADSLIGV 1222
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Zebrafish
Match: smc1b (structural maintenance of chromosomes 1B [Source:ZFIN;Acc:ZDB-GENE-091217-1])

HSP 1 Score: 123.25 bits (308), Expect = 6.143e-28
Identity = 66/217 (30.41%), Postives = 121/217 (55.76%), Query Frame = 3 
Query: 2088 PNLAAIEEYRMKEELY--MLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAE--LELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTK-NAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAVDCSLQHVCNTEKLPHPM 2723
            PNL A+E+ R  ++ Y  +L A +++ +T  +  Q  + E++K +R   F+  F  ++  + ++Y+ +     A+  L   +  +P+ +GI ++   P K +  + NLSGGEK +++LALVFA+H F+P PF+V+DE+DAALD  N+  V  + +  ++ + Q I+ISL+   Y  AD L+G+   F+            +C    +   +  P+P+
Sbjct: 1020 PNLKALEKIREVKDSYREVLDAFDISTITTKKRNQ--EFEQVKAKRFHLFSQCFEHVSVVIDQIYKKLCRNASAQAILSAENPNEPYLDGINYNCVAPGKRFMAMDNLSGGEKAIAALALVFAIHSFRPAPFFVLDEVDAALDNTNIGKVTGFFRMMSRESCQIIVISLKEEFYSRADALLGVYSMFD------------ECMFSRLLTLDLTPYPL 1222
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Xenopus
Match: SMC4 (structural maintenance of chromosomes 4 [Source:NCBI gene;Acc:100145810])

HSP 1 Score: 332.028 bits (850), Expect = 4.477e-123
Identity = 225/593 (37.94%), Postives = 336/593 (56.66%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDV------AQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKN-HQITYQD--MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE +G+MTGGG + ++G++ + V       Q+Q   ++ ++  +   K+T   +DRK      +   +  L +    +KN  +    S  +L    +++H   +  E E+N+      A  PD      +E  +++LKK+YE  + +   ++ EV ++ + I  +   KL   + +LD ++++  E    + K  +++K A++   K    +     E  ++++  +E+   LK LE+KA   + E ++    +  + +       EI  I E     +   + I  + E+ ++ + + + +I+  + +I K++ + + +  EE                               L V + EEL   K+  QI  Q   +E K ++ KPNL AI EY+ KEELY+ R AEL E+T  RD  R   E +++QR  EF AGFN+IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E+AD LIGI K  N TK+   N K +
Sbjct:  678 WRVVTLQGQIIEQSGTMTGGGGKVMKGRMGSSVMVEISDGQLQIMENKLKTDTD---KAT-AIQDRKAH----LEEGVAKLRQATREMKNTFEKYTASLQSLSE--QEVHLKAQVKELEVNV-----AAAAPDKAQQKQMEKNLEALKKEYETVAEKAGKVEAEVKRLHKLIVDINNHKLKAQQDKLDKVNKEIDECASAITKAQVSIKTADRNLKKSEEAVARTEKEIVENDKTIEELTEDLKQLEEKATAVMNECKEAEGSLPEVQEQHRNLLQEIKAIQEKEHALQKEALNIRLNIEQIESHIAEHQSKIKYWQKEITKISLHRIEDNPEE------------------------------VLAVLAQEELEAIKDPDQIINQIALLEAKSHEMKPNLGAIAEYKKKEELYLQRVAELDEITNERDNFRRAYEDLRKQRLNEFMAGFNIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEIADRLIGIYKTHNTTKSVATNPKII 1225

HSP 2 Score: 132.109 bits (331), Expect = 4.477e-123
Identity = 64/144 (44.44%), Postives = 95/144 (65.97%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEARQTN-QRAMKYRIVTL 892
            KVL  L+ Q+ SGK+ G+ GRLG+L AI  KYDVA+S++C  LD I+ + I+ AQ+CV  +K   +  +TFIGL+K+  W +K  DK     NIPR FD++ + +   R   YFA RD L+ANN+++A +   Q+  ++R+VTL
Sbjct:  541 KVLDALIQQKKSGKIPGIFGRLGDLGAIDEKYDVAISSSCGALDHIVVDTIDTAQECVNFLKKQNVGVATFIGLDKMKVW-EKGLDKIQTPENIPRLFDMVKVKDEKIRPAFYFALRDTLVANNLDQATKVAFQKDKRWRVVTL 683
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Xenopus
Match: SMC4 (structural maintenance of chromosomes 4 [Source:NCBI gene;Acc:100145810])

HSP 1 Score: 331.643 bits (849), Expect = 6.296e-123
Identity = 225/593 (37.94%), Postives = 336/593 (56.66%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDV------AQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKN-HQITYQD--MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE +G+MTGGG + ++G++ + V       Q+Q   ++ ++  +   K+T   +DRK      +   +  L +    +KN  +    S  +L    +++H   +  E E+N+      A  PD      +E  +++LKK+YE  + +   ++ EV ++ + I  +   KL   + +LD ++++  E    + K  +++K A++   K    +     E  ++++  +E+   LK LE+KA   + E ++    +  + +       EI  I E     +   + I  + E+ ++ + + + +I+  + +I K++ + + +  EE                               L V + EEL   K+  QI  Q   +E K ++ KPNL AI EY+ KEELY+ R AEL E+T  RD  R   E +++QR  EF AGFN+IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E+AD LIGI K  N TK+   N K +
Sbjct:  692 WRVVTLQGQIIEQSGTMTGGGGKVMKGRMGSSVMVEISDGQLQIMENKLKTDTD---KAT-AIQDRKAH----LEEGVAKLRQATREMKNTFEKYTASLQSLSE--QEVHLKAQVKELEVNV-----AAAAPDKAQQKQMEKNLEALKKEYETVAEKAGKVEAEVKRLHKLIVDINNHKLKAQQDKLDKVNKEIDECASAITKAQVSIKTADRNLKKSEEAVARTEKEIVENDKTIEELTEDLKQLEEKATAVMNECKEAEGSLPEVQEQHRNLLQEIKAIQEKEHALQKEALNIRLNIEQIESHIAEHQSKIKYWQKEITKISLHRIEDNPEE------------------------------VLAVLAQEELEAIKDPDQIINQIALLEAKSHEMKPNLGAIAEYKKKEELYLQRVAELDEITNERDNFRRAYEDLRKQRLNEFMAGFNIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEIADRLIGIYKTHNTTKSVATNPKII 1239

HSP 2 Score: 132.109 bits (331), Expect = 6.296e-123
Identity = 64/144 (44.44%), Postives = 95/144 (65.97%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEARQTN-QRAMKYRIVTL 892
            KVL  L+ Q+ SGK+ G+ GRLG+L AI  KYDVA+S++C  LD I+ + I+ AQ+CV  +K   +  +TFIGL+K+  W +K  DK     NIPR FD++ + +   R   YFA RD L+ANN+++A +   Q+  ++R+VTL
Sbjct:  555 KVLDALIQQKKSGKIPGIFGRLGDLGAIDEKYDVAISSSCGALDHIVVDTIDTAQECVNFLKKQNVGVATFIGLDKMKVW-EKGLDKIQTPENIPRLFDMVKVKDEKIRPAFYFALRDTLVANNLDQATKVAFQKDKRWRVVTL 697
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Xenopus
Match: SMC4 (structural maintenance of chromosomes 4 [Source:NCBI gene;Acc:100145810])

HSP 1 Score: 331.257 bits (848), Expect = 8.079e-123
Identity = 225/593 (37.94%), Postives = 336/593 (56.66%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDV------AQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKN-HQITYQD--MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE +G+MTGGG + ++G++ + V       Q+Q   ++ ++  +   K+T   +DRK      +   +  L +    +KN  +    S  +L    +++H   +  E E+N+      A  PD      +E  +++LKK+YE  + +   ++ EV ++ + I  +   KL   + +LD ++++  E    + K  +++K A++   K    +     E  ++++  +E+   LK LE+KA   + E ++    +  + +       EI  I E     +   + I  + E+ ++ + + + +I+  + +I K++ + + +  EE                               L V + EEL   K+  QI  Q   +E K ++ KPNL AI EY+ KEELY+ R AEL E+T  RD  R   E +++QR  EF AGFN+IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E+AD LIGI K  N TK+   N K +
Sbjct:  708 WRVVTLQGQIIEQSGTMTGGGGKVMKGRMGSSVMVEISDGQLQIMENKLKTDTD---KAT-AIQDRKAH----LEEGVAKLRQATREMKNTFEKYTASLQSLSE--QEVHLKAQVKELEVNV-----AAAAPDKAQQKQMEKNLEALKKEYETVAEKAGKVEAEVKRLHKLIVDINNHKLKAQQDKLDKVNKEIDECASAITKAQVSIKTADRNLKKSEEAVARTEKEIVENDKTIEELTEDLKQLEEKATAVMNECKEAEGSLPEVQEQHRNLLQEIKAIQEKEHALQKEALNIRLNIEQIESHIAEHQSKIKYWQKEITKISLHRIEDNPEE------------------------------VLAVLAQEELEAIKDPDQIINQIALLEAKSHEMKPNLGAIAEYKKKEELYLQRVAELDEITNERDNFRRAYEDLRKQRLNEFMAGFNIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEIADRLIGIYKTHNTTKSVATNPKII 1255

HSP 2 Score: 132.109 bits (331), Expect = 8.079e-123
Identity = 64/144 (44.44%), Postives = 95/144 (65.97%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEARQTN-QRAMKYRIVTL 892
            KVL  L+ Q+ SGK+ G+ GRLG+L AI  KYDVA+S++C  LD I+ + I+ AQ+CV  +K   +  +TFIGL+K+  W +K  DK     NIPR FD++ + +   R   YFA RD L+ANN+++A +   Q+  ++R+VTL
Sbjct:  571 KVLDALIQQKKSGKIPGIFGRLGDLGAIDEKYDVAISSSCGALDHIVVDTIDTAQECVNFLKKQNVGVATFIGLDKMKVW-EKGLDKIQTPENIPRLFDMVKVKDEKIRPAFYFALRDTLVANNLDQATKVAFQKDKRWRVVTL 713
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Xenopus
Match: SMC4 (structural maintenance of chromosomes 4 [Source:NCBI gene;Acc:100145810])

HSP 1 Score: 326.635 bits (836), Expect = 1.471e-121
Identity = 228/605 (37.69%), Postives = 343/605 (56.69%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDV------AQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSV-EISKINENL-------QKSKHI----HIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKN-HQITYQD--MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE +G+MTGGG + ++G++ + V       Q+Q   ++ ++  +   K+T   +DRK      +   +  L +    +KN  +    S  +L    +++H   +  E E+N+      A  PD      +E  +++LKK+YE  + +   ++ EV ++ + I  +   KL   + +LD ++++  E    + K  +++K A++   K    +     E  ++++  +E+   LK LE+KA   + E ++        +  K + S+ E+ + + NL       Q+ +H      + I  + E+ ++ + + + +I+  + +I K++ + + +  EE                               L V + EEL   K+  QI  Q   +E K ++ KPNL AI EY+ KEELY+ R AEL E+T  RD  R   E +++QR  EF AGFN+IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E+AD LIGI K  N TK+   N K +
Sbjct:  725 WRVVTLQGQIIEQSGTMTGGGGKVMKGRMGSSVMVEISDGQLQIMENKLKTDTD---KAT-AIQDRKAH----LEEGVAKLRQATREMKNTFEKYTASLQSLSE--QEVHLKAQVKELEVNVA-----AAAPDKAQQKQMEKNLEALKKEYETVAEKAGKVEAEVKRLHKLIVDINNHKLKAQQDKLDKVNKEIDECASAITKAQVSIKTADRNLKKSEEAVARTEKEIVENDKTIEELTEDLKQLEEKATAVMNECKEAETSPFCTIIRKGKGSLPEVQEQHRNLLQEIKAIQEKEHALQKEALNIRLNIEQIESHIAEHQSKIKYWQKEITKISLHRIEDNPEE------------------------------VLAVLAQEELEAIKDPDQIINQIALLEAKSHEMKPNLGAIAEYKKKEELYLQRVAELDEITNERDNFRRAYEDLRKQRLNEFMAGFNIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEIADRLIGIYKTHNTTKSVATNPKII 1284

HSP 2 Score: 132.109 bits (331), Expect = 1.471e-121
Identity = 64/144 (44.44%), Postives = 95/144 (65.97%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEARQTN-QRAMKYRIVTL 892
            KVL  L+ Q+ SGK+ G+ GRLG+L AI  KYDVA+S++C  LD I+ + I+ AQ+CV  +K   +  +TFIGL+K+  W +K  DK     NIPR FD++ + +   R   YFA RD L+ANN+++A +   Q+  ++R+VTL
Sbjct:  588 KVLDALIQQKKSGKIPGIFGRLGDLGAIDEKYDVAISSSCGALDHIVVDTIDTAQECVNFLKKQNVGVATFIGLDKMKVW-EKGLDKIQTPENIPRLFDMVKVKDEKIRPAFYFALRDTLVANNLDQATKVAFQKDKRWRVVTL 730
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Xenopus
Match: SMC4 (structural maintenance of chromosomes 4 [Source:NCBI gene;Acc:100145810])

HSP 1 Score: 327.02 bits (837), Expect = 1.547e-121
Identity = 228/605 (37.69%), Postives = 343/605 (56.69%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDV------AQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSV-EISKINENL-------QKSKHI----HIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKN-HQITYQD--MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE +G+MTGGG + ++G++ + V       Q+Q   ++ ++  +   K+T   +DRK      +   +  L +    +KN  +    S  +L    +++H   +  E E+N+      A  PD      +E  +++LKK+YE  + +   ++ EV ++ + I  +   KL   + +LD ++++  E    + K  +++K A++   K    +     E  ++++  +E+   LK LE+KA   + E ++        +  K + S+ E+ + + NL       Q+ +H      + I  + E+ ++ + + + +I+  + +I K++ + + +  EE                               L V + EEL   K+  QI  Q   +E K ++ KPNL AI EY+ KEELY+ R AEL E+T  RD  R   E +++QR  EF AGFN+IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E+AD LIGI K  N TK+   N K +
Sbjct:  732 WRVVTLQGQIIEQSGTMTGGGGKVMKGRMGSSVMVEISDGQLQIMENKLKTDTD---KAT-AIQDRKAH----LEEGVAKLRQATREMKNTFEKYTASLQSLSE--QEVHLKAQVKELEVNVA-----AAAPDKAQQKQMEKNLEALKKEYETVAEKAGKVEAEVKRLHKLIVDINNHKLKAQQDKLDKVNKEIDECASAITKAQVSIKTADRNLKKSEEAVARTEKEIVENDKTIEELTEDLKQLEEKATAVMNECKEAETSPFCTIIRKGKGSLPEVQEQHRNLLQEIKAIQEKEHALQKEALNIRLNIEQIESHIAEHQSKIKYWQKEITKISLHRIEDNPEE------------------------------VLAVLAQEELEAIKDPDQIINQIALLEAKSHEMKPNLGAIAEYKKKEELYLQRVAELDEITNERDNFRRAYEDLRKQRLNEFMAGFNIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEIADRLIGIYKTHNTTKSVATNPKII 1291

HSP 2 Score: 132.109 bits (331), Expect = 1.547e-121
Identity = 64/144 (44.44%), Postives = 95/144 (65.97%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEARQTN-QRAMKYRIVTL 892
            KVL  L+ Q+ SGK+ G+ GRLG+L AI  KYDVA+S++C  LD I+ + I+ AQ+CV  +K   +  +TFIGL+K+  W +K  DK     NIPR FD++ + +   R   YFA RD L+ANN+++A +   Q+  ++R+VTL
Sbjct:  595 KVLDALIQQKKSGKIPGIFGRLGDLGAIDEKYDVAISSSCGALDHIVVDTIDTAQECVNFLKKQNVGVATFIGLDKMKVW-EKGLDKIQTPENIPRLFDMVKVKDEKIRPAFYFALRDTLVANNLDQATKVAFQKDKRWRVVTL 737
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Mouse
Match: Smc4 (structural maintenance of chromosomes 4 [Source:MGI Symbol;Acc:MGI:1917349])

HSP 1 Score: 330.487 bits (846), Expect = 1.365e-123
Identity = 220/589 (37.35%), Postives = 324/589 (55.01%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTE--QSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQD---MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE +G+M+GGGS+ +RG++ + V         ++     E  S +  Q +++K Q    V+     L      ++N ++  KF+ +     ++ L   EE    ++  LE  +    PD K   LLE  +   KK+Y+  + +   ++ E+ ++   I  +   KL   +++LD I++Q  E    + K  +A+K A++   K  + +     E    E+   ++   LK +E KA + +   +     +  + K       E+  I EN    +   + I    E+    + +   +I+  + +I K+  +P+ +   E                              T+ V S EEL   KN +    +   +E +  + KPNL AI EY+ KE+LY+ R AEL ++T  RD  R   E +++QR  EF AGF +IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E++D LIGI K +N TK+  +N K +
Sbjct:  708 WRVVTLQGQIIEQSGTMSGGGSKVMRGRMGSSVIDEISVEEVNKMESQLERHSKQAMQIQEQKVQHEEAVVK----LRHSERDMRNTLE--KFAAS-----IQGLSEQEEYLCVQIKELEANVLTTAPDRKQQKLLEENVSVFKKEYDAVAEKAGKVEAEIKRLHNTIIDINNRKLKAQQNKLDTINKQLDECASAITKAQVAIKTADRNLKKAQDSVCRTEKEIKDTEKEINDLKTELKNIEDKAEEVINNTKTAETSLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHISEHNSKIKYWQKEISKIKLHPVEDNPVE------------------------------TVAVLSQEELEAIKNPESITNEIALLEAQCREMKPNLGAIAEYKKKEDLYLQRVAELDKITSERDNFRQAYEDLRKQRLNEFMAGFYVITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIYKTYNSTKSVAVNPKQI 1255

HSP 2 Score: 134.42 bits (337), Expect = 1.365e-123
Identity = 65/144 (45.14%), Postives = 95/144 (65.97%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            KVL  ++ ++ SG++ G+ GRLG+L AI  KYD+A+S+ C  LD I+ + I+ AQ+CV  +K H I  +TFIGL+K+  W KK + K     N PR FDL+ + N + R   YFA RD L+ANN+++A R   QR  ++R+VTL
Sbjct:  571 KVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDIAISSCCHALDYIVVDSIDTAQECVNFLKKHNIGIATFIGLDKMTVWAKKMS-KIQTPENTPRLFDLVKVKNEEIRQAFYFALRDTLVANNLDQATRVAYQRDRRWRVVTL 713
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Mouse
Match: Smc4 (structural maintenance of chromosomes 4 [Source:MGI Symbol;Acc:MGI:1917349])

HSP 1 Score: 330.487 bits (846), Expect = 1.695e-123
Identity = 220/589 (37.35%), Postives = 324/589 (55.01%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTE--QSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQD---MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE +G+M+GGGS+ +RG++ + V         ++     E  S +  Q +++K Q    V+     L      ++N ++  KF+ +     ++ L   EE    ++  LE  +    PD K   LLE  +   KK+Y+  + +   ++ E+ ++   I  +   KL   +++LD I++Q  E    + K  +A+K A++   K  + +     E    E+   ++   LK +E KA + +   +     +  + K       E+  I EN    +   + I    E+    + +   +I+  + +I K+  +P+ +   E                              T+ V S EEL   KN +    +   +E +  + KPNL AI EY+ KE+LY+ R AEL ++T  RD  R   E +++QR  EF AGF +IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E++D LIGI K +N TK+  +N K +
Sbjct:  733 WRVVTLQGQIIEQSGTMSGGGSKVMRGRMGSSVIDEISVEEVNKMESQLERHSKQAMQIQEQKVQHEEAVVK----LRHSERDMRNTLE--KFAAS-----IQGLSEQEEYLCVQIKELEANVLTTAPDRKQQKLLEENVSVFKKEYDAVAEKAGKVEAEIKRLHNTIIDINNRKLKAQQNKLDTINKQLDECASAITKAQVAIKTADRNLKKAQDSVCRTEKEIKDTEKEINDLKTELKNIEDKAEEVINNTKTAETSLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHISEHNSKIKYWQKEISKIKLHPVEDNPVE------------------------------TVAVLSQEELEAIKNPESITNEIALLEAQCREMKPNLGAIAEYKKKEDLYLQRVAELDKITSERDNFRQAYEDLRKQRLNEFMAGFYVITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIYKTYNSTKSVAVNPKQI 1280

HSP 2 Score: 134.42 bits (337), Expect = 1.695e-123
Identity = 65/144 (45.14%), Postives = 95/144 (65.97%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            KVL  ++ ++ SG++ G+ GRLG+L AI  KYD+A+S+ C  LD I+ + I+ AQ+CV  +K H I  +TFIGL+K+  W KK + K     N PR FDL+ + N + R   YFA RD L+ANN+++A R   QR  ++R+VTL
Sbjct:  596 KVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDIAISSCCHALDYIVVDSIDTAQECVNFLKKHNIGIATFIGLDKMTVWAKKMS-KIQTPENTPRLFDLVKVKNEEIRQAFYFALRDTLVANNLDQATRVAYQRDRRWRVVTL 738
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Mouse
Match: Smc1a (structural maintenance of chromosomes 1A [Source:MGI Symbol;Acc:MGI:1344345])

HSP 1 Score: 132.494 bits (332), Expect = 8.747e-31
Identity = 71/198 (35.86%), Postives = 119/198 (60.10%), Query Frame = 3 
Query: 2061 MEDKLNKQK--------PNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAE--LELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDR-TKNAQFIIISLRNNMYELADCLIGI 2621
            ++ KLN+Q+        PN+ A+E+     + +   + E     +   + +   E++K++R   F A F  + T + E+Y+ ++    A+  L   +  +P+ +GI ++   P K ++ + NLSGGEKT+++LAL+FA+H +KP PF+V+DEIDAALD  N+  VANYIK++ T N Q I+ISL+   Y  A+ LIG+
Sbjct: 1006 LQQKLNEQQSVLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKEQSTCNFQAIVISLKEEFYTKAESLIGV 1203
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Mouse
Match: Smc1b (structural maintenance of chromosomes 1B [Source:MGI Symbol;Acc:MGI:2154049])

HSP 1 Score: 125.176 bits (313), Expect = 1.534e-28
Identity = 63/181 (34.81%), Postives = 105/181 (58.01%), Query Frame = 3 
Query: 2187 RDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAE--LELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNA-QFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAVDCSLQHVCNTEKLPHP 2720
            R + E++KR+R+  F+  F  I+  + ++Y+ +     A+  L   +  +P+ +GI ++   P K +  + NLSGGEK +++LAL+FA+H F+P PF+V+DE+DAALD  N+  V++YIK++++   Q IIISL+   Y  AD LIG+    N            +C   HV   +   +P
Sbjct: 1051 RQEFEQVKRRRYDAFSQCFEHISVSIDQIYKKLCRNNSAQAFLSPENPEEPYLDGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQSQEQFQMIIISLKEEFYSKADALIGVYPEHN------------ECMFSHVLTLDLSKYP 1219
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Mouse
Match: Smc4 (structural maintenance of chromosomes 4 [Source:MGI Symbol;Acc:MGI:1917349])

HSP 1 Score: 82.4185 bits (202), Expect = 2.989e-18
Identity = 36/77 (46.75%), Postives = 55/77 (71.43%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKV 694
            KVL  ++ ++ SG++ G+ GRLG+L AI  KYD+A+S+ C  LD I+ + I+ AQ+CV  +K H I  +TFIGL+K+
Sbjct:   32 KVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDIAISSCCHALDYIVVDSIDTAQECVNFLKKHNIGIATFIGLDKL 108
[Close]
BLAST of Structural maintenance of chromosomes protein vs. UniProt/SwissProt
Match: sp|Q9ERA5|SMC4_MICAR (Structural maintenance of chromosomes protein 4 (Fragment) OS=Microtus arvalis OX=47230 GN=SMC4 PE=2 SV=1)

HSP 1 Score: 340.887 bits (873), Expect = 2.684e-124
Identity = 227/594 (38.22%), Postives = 332/594 (55.89%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEE---DNEKELNILEGKLKAN----KPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKN-HQITYQD--MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE +G+MTGGGS+ +RG++ + V                  + +E+  ++ E +L     Q   + E+    + R+   + S+  ++N L+      +   D E+ L +   +L+AN     PD K   LLE  + + KK+Y+  + +   ++ EV ++ + I  +   KL   +++LD I++Q  E    + K  +A+K A++   K  + +     E    E+   ++ A LK +E KA + + +     E +  + K       E+  I EN    +   + I    E+    + +   +I+  + +I K+  +P+ +   E                              T+ V S E+L   KN   IT Q   +E + ++ KPNL AI EY+ KEELY+ R AEL ++T  RD  R   E +++QR  EF AGF +IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E++D LIGI K +N TK+  +N K +
Sbjct:  690 WRVVTLQGQIIEQSGTMTGGGSKVMRGRMGSSVI----------------VEISEEEVNKMESQLQKHSKQARRIQEQKVQHEERVVKLRHSEREMRNTLEKFAASIQGLSDQEEYLTVQIKELEANVLTTAPDKKKQKLLEENVSAFKKEYDAVAEKAGKVEAEVKRLHDTIIEINNRKLKAQQNKLDMINKQLDECASAITKAQVAIKTADRNLIKAQDSVVRTEKEIKDTEKETNDLKAELKAIEDKAEEVIKKTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHIAEHNSKIKYWQKEISKIKLHPIEDNPVE------------------------------TVSVLSPEDLEAIKNPDSITNQIAILEAQCHEMKPNLGAIAEYKKKEELYLQRVAELDKITSERDNFRQAYEDLRKQRLNEFMAGFYIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIYKTYNITKSVAVNPKEI 1237

HSP 2 Score: 129.413 bits (324), Expect = 2.684e-124
Identity = 63/144 (43.75%), Postives = 93/144 (64.58%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            KVL  ++ ++ SG++ G+ GRLG+L AI  KYD+A+S+ C  LD I+ + I+ AQ+CV  +K H I  +TFIGL+K+  W KK   K     N PR FDL+   N + R   YFA RD L+A+N+++A R   Q+  ++R+VTL
Sbjct:  553 KVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDIAISSCCHALDYIVVDSIDTAQECVNFLKRHNIGVATFIGLDKMTVWAKKMA-KIQTPENTPRLFDLVKAKNEEIRQAFYFALRDTLVADNLDQATRVAYQKDRRWRVVTL 695
[Close]
BLAST of Structural maintenance of chromosomes protein vs. UniProt/SwissProt
Match: sp|Q8CG47|SMC4_MOUSE (Structural maintenance of chromosomes protein 4 OS=Mus musculus OX=10090 GN=Smc4 PE=1 SV=1)

HSP 1 Score: 330.487 bits (846), Expect = 1.033e-122
Identity = 220/589 (37.35%), Postives = 324/589 (55.01%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTE--QSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQD---MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE +G+M+GGGS+ +RG++ + V         ++     E  S +  Q +++K Q    V+     L      ++N ++  KF+ +     ++ L   EE    ++  LE  +    PD K   LLE  +   KK+Y+  + +   ++ E+ ++   I  +   KL   +++LD I++Q  E    + K  +A+K A++   K  + +     E    E+   ++   LK +E KA + +   +     +  + K       E+  I EN    +   + I    E+    + +   +I+  + +I K+  +P+ +   E                              T+ V S EEL   KN +    +   +E +  + KPNL AI EY+ KE+LY+ R AEL ++T  RD  R   E +++QR  EF AGF +IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E++D LIGI K +N TK+  +N K +
Sbjct:  733 WRVVTLQGQIIEQSGTMSGGGSKVMRGRMGSSVIDEISVEEVNKMESQLERHSKQAMQIQEQKVQHEEAVVK----LRHSERDMRNTLE--KFAAS-----IQGLSEQEEYLCVQIKELEANVLTTAPDRKQQKLLEENVSVFKKEYDAVAEKAGKVEAEIKRLHNTIIDINNRKLKAQQNKLDTINKQLDECASAITKAQVAIKTADRNLKKAQDSVCRTEKEIKDTEKEINDLKTELKNIEDKAEEVINNTKTAETSLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHISEHNSKIKYWQKEISKIKLHPVEDNPVE------------------------------TVAVLSQEELEAIKNPESITNEIALLEAQCREMKPNLGAIAEYKKKEDLYLQRVAELDKITSERDNFRQAYEDLRKQRLNEFMAGFYVITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIYKTYNSTKSVAVNPKQI 1280

HSP 2 Score: 134.42 bits (337), Expect = 1.033e-122
Identity = 65/144 (45.14%), Postives = 95/144 (65.97%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            KVL  ++ ++ SG++ G+ GRLG+L AI  KYD+A+S+ C  LD I+ + I+ AQ+CV  +K H I  +TFIGL+K+  W KK + K     N PR FDL+ + N + R   YFA RD L+ANN+++A R   QR  ++R+VTL
Sbjct:  596 KVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDIAISSCCHALDYIVVDSIDTAQECVNFLKKHNIGIATFIGLDKMTVWAKKMS-KIQTPENTPRLFDLVKVKNEEIRQAFYFALRDTLVANNLDQATRVAYQRDRRWRVVTL 738
[Close]
BLAST of Structural maintenance of chromosomes protein vs. UniProt/SwissProt
Match: sp|Q9NTJ3|SMC4_HUMAN (Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2)

HSP 1 Score: 338.576 bits (867), Expect = 4.812e-122
Identity = 224/590 (37.97%), Postives = 329/590 (55.76%), Query Frame = 3 
Query:  936 VKGELIEVTGSMTGGGSRQVRGKICTD-VAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEE---DNEKELNI----LEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKN-HQITYQD--MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            ++G++IE +G+MTGGGS+ ++G++ +  V +I                 +E+  ++ E +L +   +   + E+   L+ R+   + S+  ++N L+      +   + E+ LN+    LE  + A  PD K   LLE  + + K +Y+  + +   ++ EV ++   I  +   KL   + +LD I++Q  E    + K  +A+K A++   K  + +     E    E+   ++ A LK LE KA + +       E +  + K       E+  I EN    +   + I    E+    + +   +I+    +I K++ +P+ +   E+                              + V S E+L   KN   IT Q   +E + ++ KPNL AI EY+ KEELY+ R AEL ++T  RD  R   E +++QR  EF AGF +IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E++D LIGI K +N TK+  +N K +
Sbjct:  740 LQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEI-----------------SEEEVNKMESQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVKELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEE------------------------------ISVLSPEDLEAIKNPDSITNQIALLEARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFYIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIYKTYNITKSVAVNPKEI 1282

HSP 2 Score: 124.02 bits (310), Expect = 4.812e-122
Identity = 61/144 (42.36%), Postives = 92/144 (63.89%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            KVL  ++ ++ SG++ G+ GRLG+L AI  KYDVA+S+ C  LD I+ + I+ AQ+CV  +K   I  +TFIGL+K+  W KK  +      N PR FDL+ + +   R   YFA RD L+A+N+++A R   Q+  ++R+VTL
Sbjct:  598 KVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKRQNIGVATFIGLDKMAVWAKKMTE-IQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADNLDQATRVAYQKDRRWRVVTL 740
[Close]
BLAST of Structural maintenance of chromosomes protein vs. UniProt/SwissProt
Match: sp|P50532|SMC4_XENLA (Structural maintenance of chromosomes protein 4 OS=Xenopus laevis OX=8355 GN=smc4 PE=1 SV=1)

HSP 1 Score: 332.413 bits (851), Expect = 5.635e-122
Identity = 226/593 (38.11%), Postives = 336/593 (56.66%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDVA------QIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKN-HQITYQD--MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE +G+MTGGG + ++G++ + V       Q+QK  ++ ++      ++TE  +DRK      +  ++  L +    +KN  +    S  +L    +++H   +  E E+N+      A  PD      +E  +++LKK+YEK + +   ++ EV ++ + I  +   KL   + +LD + ++  E    + K  +++K A++   K    +     E   ++++ +E+   LK LE+KA   + E ++    +  + +       EI  I E     +   + I  + E+  + + + + +I+  + +I K++ + + +  EE                               L   + EEL   K+  QI  Q   +E K ++ KPNL AI EY+ KEELY+ R AEL E+T  RD  R   E +++QR  EF AGFN+IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E+AD LIGI K  N TK+   N K +
Sbjct:  729 WRVVTLQGQIIEQSGTMTGGGGKVMKGRMGSSVMVEISDDQLQKMENKLKTDTT---RATE-IQDRKAH----LEEEVAKLRQATREMKNTFEKYTASLQSLSE--QEVHLKAQVKELEVNVA-----AAAPDKNQQKQMEKNLETLKKEYEKVAEKAGKVEAEVKRLHKLIVDINNHKLKAQQDKLDKVTKEIDECASAITKAQVSIKTADRNLKKSEEAVARTEKEIVANDKSIEELTEDLKKLEEKATTVMNECKEAECSLPEVQEQHRSLLQEIKAIQEKEHALQKEALNIRLNIEQIDSHIAEHQSKIKYWQKEITKISLHKIEDIPEE------------------------------VLPGLAQEELEAIKDPDQIINQIALLEAKSHEMKPNLGAIAEYKKKEELYLQRVAELDEITNERDSFRRAYEDLRKQRLNEFMAGFNIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEIADRLIGIYKTHNTTKSVATNPKII 1276

HSP 2 Score: 129.798 bits (325), Expect = 5.635e-122
Identity = 63/144 (43.75%), Postives = 94/144 (65.28%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            KVL  L+ Q+ SGK+ G+ GRLG+L AI  KYDVA+S++C  LD I+ + I+ AQ+CV  +K   +  +TFIGL+K+  W K  N K     NIPR FD++ + +   +   YFA RD ++ANN+++A R   Q+  ++R+VTL
Sbjct:  592 KVLDALIQQKKSGKIPGIFGRLGDLGAIDEKYDVAISSSCGALDHIVVDTIDTAQECVNFLKKQNVGVATFIGLDKMKVWEKGLN-KIQTPENIPRLFDMVKVKDEQIKPAFYFALRDTIVANNLDQATRVAFQKDKRWRVVTL 734
[Close]
BLAST of Structural maintenance of chromosomes protein vs. UniProt/SwissProt
Match: sp|Q9FJL0|SMC4_ARATH (Structural maintenance of chromosomes protein 4 OS=Arabidopsis thaliana OX=3702 GN=SMC4 PE=1 SV=1)

HSP 1 Score: 308.531 bits (789), Expect = 3.435e-87
Identity = 213/611 (34.86%), Postives = 331/611 (54.17%), Query Frame = 3 
Query:  912 IYFATAYRVKGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRD---------------RSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEK---ELNILEGKLK----ANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXS----LGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKL--TFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLN 2660
             Y A    V  + ++    +  GG+R+ R  +  D A  +KS                   R++G      + ++    E EL+ +++ +NN+ EK   + N ++  + ++N +  L  +L + + + E    E N LE +L     A++P    +      ++ LKK   K+   +++L++   ++ +++++     G  KL   K++++ I     +    + + N+ ++  +KL  KLT  ++    EK + E   + +  T K + +KA +    Y+K  + +     +      +   + +++ + K   +      ++ K   +++++R +  K  +  L   F    E +++D  D   +       ++N     K +     L                    +E +L +  PNL +I EYR K ELY  R  EL  VTQ RD  R Q ++++++R  EF AGFN I+ KLKEMYQMIT+GGDAELELVDSLDPFSEG++FSVRPPKKSWKNI+NLSGGEKTLSSLALVFALHH+KPTP YVMDEIDAALDFKNVSIV +Y+KDRTK+AQFIIISLRNNM+ELAD L+GI K  N TK+  +N
Sbjct:  651 FYAALGNTVVAKDLDQATRIAYGGNREFRRVVALDGALFEKSGTMSGGGGKARGGRMGTSIRATG-----VSGEAVANAENELSKIVDMLNNIREK---VGNAVRQYRAAENEVSGLEMELAKSQREIESLNSEHNYLEKQLASLEAASQPKTDEI----DRLKELKKIISKEEKEIENLEKGSKQLKDKLQTNIENAGGEKLKGQKAKVEKIQTDIDKNNTEINRCNVQIETNQKLIKKLTKGIEEATREKERLEGEKENLHVTFKDITQKAFEIQETYKKTQQLIDEHKDVLTGAKSDYENLKKSVDELKASRVDAEFKVQDMKKKYNELEMREKGYKKKLNDLQIAFTKHMEQIQKDLVDPDKLQATLMDNNLNEACDLKRALEMVAL--------------------LEAQLKELNPNLDSIAEYRSKVELYNGRVDELNSVTQERDDTRKQYDELRKRRLDEFMAGFNTISLKLKEMYQMITLGGDAELELVDSLDPFSEGVVFSVRPPKKSWKNIANLSGGEKTLSSLALVFALHHYKPTPLYVMDEIDAALDFKNVSIVGHYVKDRTKDAQFIIISLRNNMFELADRLVGIYKTDNCTKSITIN 1229

HSP 2 Score: 92.8189 bits (229), Expect = 1.123e-17
Identity = 44/134 (32.84%), Postives = 82/134 (61.19%), Query Frame = 2 
Query:  446 SKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA 847
            S++++++VL  ++  + + +++G+ GR+G+L AI  KYDVA+STAC  LD I+ E  + AQ CVEL++   +  +TF+ L K      K  +K     ++PR FDL+ + +   +   Y A  + ++A ++++A
Sbjct:  534 SEKSQNEVLKAVLRAKENNQIEGIYGRMGDLGAIDAKYDVAISTACAGLDYIVVETTSSAQACVELLRKGNLGFATFMILEKQTDHIHKLKEKVKTPEDVPRLFDLVRVKDERMKLAFYAALGNTVVAKDLDQA 667
[Close]
BLAST of Structural maintenance of chromosomes protein vs. TrEMBL
Match: A0A3M6TVW6 (Structural maintenance of chromosomes protein OS=Pocillopora damicornis OX=46731 GN=pdam_00012938 PE=3 SV=1)

HSP 1 Score: 372.859 bits (956), Expect = 1.598e-134
Identity = 236/593 (39.80%), Postives = 355/593 (59.87%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGK----ICTDV-----AQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTT--KFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQ--DMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLN 2660
            +RV   +GE+I+ +G+M+GGG++ V+G+    I +DV       ++K+  +       E K+ E+ R+ K++           L E  + LK  + T   +  +NN++  +K L   EE+  +++  L+ K+  + PD   + +LE ++ + +K++         ++ EV K+ ++I  +G +KL   + R+D +     E  G + K N+A+K   + T K    +++L  E  ++  N ++++   K LE+KA   L +Y+K  EE+  + +  E    E++ + +   K K   + I  + E+ ++++ + + +++  + ++ +LT        E ++++                           L   S  EL       + Y+   +E+KL + KPN+AAI EYR KEE Y+ R  +L EVT  RD +R + + M++QR  EF AGF++ITTKLKEMYQMIT+GGDAELELVDSLDPFSEGI+FSVRPPKKSWKNISNLSGGEKTLSSLALVFALHH+KPTP YVMDEIDAALDF+NVSIVANYIK+RTKNAQFIIISLRNNM+ELAD LIGI K  N TK+  +N
Sbjct:  658 WRVVTLQGEIIDQSGTMSGGGNKVVKGRMGSSIVSDVNPNQLKAMEKTLEK-------ETKAAEEYREAKKR-----------LEEIVDELKKELSTAEHQLQKNNME--IKALDDQEENLRQQIVHLKNKVVESTPDETRLKVLEDSVTTHEKEWRTAVSSSSRIETEVQKLHKQIMEIGGSKLKMQQDRVDVLTNAVDEVVGQMTKANVAIKTCHRNTRKAEGTVESLEREIGENSANIQKLEEDFKTLEEKATKVLEDYEKAQEEMLAMEESLEFLKKEVAVVEQEETKMKSKEVDIKHEVEKYESVLKENQQKVKHWQKELSRLTLVSASVIAEAEADEG--------------------------LPTLSRGELEGIDKETVMYEITVLEEKLKQMKPNIAAIAEYRKKEEAYLDRVKDLDEVTVQRDHKRKEHDAMRKQRLDEFMAGFSVITTKLKEMYQMITLGGDAELELVDSLDPFSEGIVFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHYKPTPLYVMDEIDAALDFRNVSIVANYIKERTKNAQFIIISLRNNMFELADRLIGIFKTDNCTKSVAIN 1204

HSP 2 Score: 139.043 bits (349), Expect = 1.598e-134
Identity = 67/155 (43.23%), Postives = 106/155 (68.39%), Query Frame = 2 
Query:  437 SRQSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEARQTN---QRAMKYRIVTL 892
            S Q+  +  +VL  LM Q++SGK+ G++GRLG+L AI  KYDVA+STAC  LD+I+ + I+ AQKC+  +K + I   TF+GL+KV +W K A++K     N+PR +DL+ + N+  R   +FA R+ L+A+++++A  TN   Q + ++R+VTL
Sbjct:  511 SLQASHSRGQVLEALMQQKASGKIPGILGRLGDLGAIDDKYDVAISTACGALDNIVCDSIDTAQKCITFLKHNNIGSGTFLGLDKVEKWRKDASNKIKTPQNVPRLYDLVQVKNDQIRTAFFFALRNTLVADDLKQA--TNIAFQGSNRWRVVTL 663
[Close]
BLAST of Structural maintenance of chromosomes protein vs. TrEMBL
Match: C3YK10 (SMC hinge domain-containing protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_80430 PE=4 SV=1)

HSP 1 Score: 370.933 bits (951), Expect = 1.626e-128
Identity = 230/578 (39.79%), Postives = 332/578 (57.44%), Query Frame = 3 
Query:  942 GELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRD---RKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQ--DMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLN 2660
            G+LI++ G+MTGGG++ ++G++ + V              +F PK  E       R  Q+   +  +   L E  + L+  +   K  Q      +K L   E   ++++  L+ ++K  +PD      LE  + + KK+YEK +     ++ EV  + ++I  +  +K+ + + +LD ++++  E    + K  +A K A++   K  + +  L  +   ++    + +A L  LE+KA + L  +Q+  E++Q +  +  E   E+  +     + K  H+ I    EEK   V +   +++  K +I+K+  + +                              D      LK  S EE+      ++ YQ    E KL + KPN+AAI EY+ KE+LY+ R +EL E+T  RDQQR   E +++QR  EF AGF +IT KLKEMYQMIT+GGDAELELVDSLDPFSEGI+FSVRPPKKSWKNISNLSGGEKTLSSLALVFALHH+KPTP YVMDEIDAALDFKNVSIVA+YIK+RTKNAQFIIISLRNNM+ELAD L+GI K  N TK+  ++
Sbjct:  608 GQLIDIAGTMTGGGTKVIKGRMGSSVV------------SDFNPKEMENMESKLARLSQQAQQLKERKRGLEETVQRLERELTKIKMDQKKFDMDIKALTEQEVTLKQQVTELQQQVKEAEPDKTQQAKLEKTLAAHKKEYEKAAEASSKVEAEVQSLHKKIMDISNSKMKSAQDKLDQVNKEIDEANAAVTKAKVANKTAKRNITKTEDKIGKLEKDIEDNKTAVGQFEADLTALEEKATEVLNLFQETKEKMQEVEAVAAEIQKELDVLEAKENELKSSHVDIKHQLEEKVTAVKENSAKVKFWKKEIEKMVVHVV------------------------------DDDGPPELKELSEEEVKAIDKKELGYQITVQEAKLGEFKPNMAAINEYKKKEQLYLKRVSELDEITSRRDQQRKAYEDLRKQRLDEFMAGFGVITNKLKEMYQMITLGGDAELELVDSLDPFSEGIVFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHYKPTPLYVMDEIDAALDFKNVSIVASYIKERTKNAQFIIISLRNNMFELADRLVGIYKTNNSTKSVAID 1143

HSP 2 Score: 121.324 bits (303), Expect = 1.626e-128
Identity = 64/158 (40.51%), Postives = 93/158 (58.86%), Query Frame = 2 
Query:  437 SRQSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTLNVTFV 907
            S Q + +  KV   LM Q+ SGK+ G+ GRLG+L AI  KYDVA+STAC  LD I+ + ++ AQKCV  +K + I R TF+GL++                NIPR FDL+ + +       YFA RD L+A+N+++A R   Q + ++R+VTL    +
Sbjct:  470 SMQQQRSRGKVQEALMLQKQSGKIPGIFGRLGDLGAIDDKYDVAISTACGGLDLILVDTMDTAQKCVNFLKKNDIGRGTFLGLDQ----------------NIPRLFDLVKVKDERTLPAFYFALRDTLVADNLDQATRCAFQGSKRFRVVTLGGQLI 611
[Close]
BLAST of Structural maintenance of chromosomes protein vs. TrEMBL
Match: A0A0N7ZBS8 (Structural maintenance of chromosomes protein OS=Scylla olivacea OX=85551 PE=3 SV=1)

HSP 1 Score: 365.925 bits (938), Expect = 1.248e-127
Identity = 238/605 (39.34%), Postives = 353/605 (58.35%), Query Frame = 3 
Query:  942 GELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRD-RKEQ-ELNDVINQIN----NLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQD--MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAVDCSLQHVCNTEKLPHPMILN 2732
            GELIE  G+M+GGG   +RG++    A +       + + N   + T+++ + RKE+ +L D ++Q+     N+N+  +  K  I   +    NLQ              ++  + E K+K+ K DP  +  +E  I   KK Y+K +   + ++ EV KI ++I  +   K+  +K  LDA++++  +    + K+ +A+K A++ + K  +++  +  E  + +E  + M A    +E+ A   +   + +++E + L     E   E  K  +   K K   I+I ++ ++ + ++ + K +    K  I +L                       E  DI I   ++D+    TL+    +EL +    Q+ YQ   +++KL + KPNLA I+EYR KEE+Y+ RAAEL E+T+ RD+QR   E +++QR  EF AGF +I+ KLKEMYQMIT+GGDAELELVDSLDPFSEG++FSVRPPKKSWKNI+NLSGGEKTLSSLALVFALH++KPTP YVMDEIDAALDFKNVSIV NY+K+RTKNAQFIIISLR+ M+ELAD L+GI K +N TK+  +N   +  SL   C     P    LN
Sbjct:  733 GELIEAVGTMSGGGKTVLRGRMGKQAAIVNVDPQEVQGAENKVEELTQRTMELRKERGQLEDSVHQLTKDLKNMNQDCQKFKMEIDAAEQQLVNLQ--------------RQKGVQEEKVKSVKSDPAKIKAMEKDIAEKKKVYQKAAASAEEVEAEVTKIHKQIMQVTGGKMKELKKALDAVNKRLEKVNAEITKLQVAIKTAKRNSKKTQDNIAAMEKELVEVQEELRGMQAKRLEIEQAAAKVIEALETVAQEDEELGTQMAELKAERDKCVKEENKIKSAKIEIDQELDKYEEVIKENKSKASHAKKKISRL-----------------------ELADIPINKEEEDNAELVTLE---PDELKELDPKQLEYQVTVLQEKLQESKPNLAVIQEYRKKEEMYLQRAAELDEITRQRDEQRKYHEDLRKQRLNEFMAGFTIISNKLKEMYQMITLGGDAELELVDSLDPFSEGLIFSVRPPKKSWKNITNLSGGEKTLSSLALVFALHYYKPTPLYVMDEIDAALDFKNVSIVGNYVKERTKNAQFIIISLRSQMFELADRLVGIYKTYNTTKSVTINPAKIMASLGEECT----PASTTLN 1293

HSP 2 Score: 123.25 bits (308), Expect = 1.248e-127
Identity = 55/155 (35.48%), Postives = 94/155 (60.65%), Query Frame = 2 
Query:  443 QSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEARQTNQRAMKYRIVTLNVTFV 907
            QS  +  +V+  +M Q+ +G +KGV GRLG+L  I  KYDVA+STAC  LD+I+ + +   ++C+  +K   I  +TFI L+K+ +W            N+PR +DL+ I ++  +   YFA RD L+A ++++A + + +  ++R+VTLN   +
Sbjct:  582 QSSRSRGRVMDAIMEQKRNGNIKGVFGRLGDLGGIDEKYDVAISTACGALDNIVVDGVETGKRCINFLKQSNIGTATFIALDKMEKWRVNCERPMNTPENVPRLYDLVRISDDRVKTAFYFALRDTLVATDLDQASRISYQKGRHRVVTLNGELI 736
[Close]
BLAST of Structural maintenance of chromosomes protein vs. TrEMBL
Match: E7FGC2 (Structural maintenance of chromosomes protein OS=Danio rerio OX=7955 GN=smc4 PE=1 SV=2)

HSP 1 Score: 348.591 bits (893), Expect = 1.648e-124
Identity = 222/595 (37.31%), Postives = 329/595 (55.29%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGK----ICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEED-NEKELNI------LEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE  G+MTGGG R ++G+    +C DV                    T++  D+ E  LN  + Q+ +  ++   L+ ++   +    +++N L+      +   E+EL++      LE  + A  PD      +E ++++ +K +E  S +   ++ EV ++   I  +   KL   + +LD I+ Q  + +  + K  +A+K A +   K  + +  L  E +++E+  +E+   LK LE++AG+ +  YQ+  E +  +         EI  + E     +   + +    E     + +   +I+  + +  KL  + + +GV  +       D + + G+ ++                 NE  L           +ED+    KPNL AI E++ KEELY+ R AEL ++T  RD  +   E +++QR  EF AGFN+IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHHFKPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E+AD LIGI K  N TK   +N K +
Sbjct:  734 WRVVTLQGQIIEQAGTMTGGGGRVMKGRMGSSVCADV--------------------TQEQLDKMESALNKEVTQLQDCQKRKNQLEEKVHKARCELRDMKNTLEKYTATIQSLTEQELHLKPQIKDLEANVIAAAPDKAKQKQMEKSLEAYRKDFEAASNKAGKVEAEVKRLHTLIVDINSHKLKAQQDKLDQINTQLDQCSSAVTKAQVAIKTAGRNLKKSEDGVSRLEQEISENEKLMEELTEQLKKLEEQAGEIMQSYQQAEEALPEVQDQHRAVVQEIKALQEQEHALQKESLSVRLKVEHIDTAITECHNKIKHWQKEASKLCLHHI-DGVPAEELPALNPDQLQDIGNPDVIK---------------NEIAL-----------LEDRCANMKPNLGAIAEFKKKEELYLQRVAELDDITTQRDSFKRGCEDLRKQRLHEFMAGFNIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIYNLSGGEKTLSSLALVFALHHFKPTPLYFMDEIDAALDFKNVSIVACYIYEQTKNAQFIIISLRNNMFEMADRLIGIYKTHNTTKNVAINPKTI 1281

HSP 2 Score: 130.183 bits (326), Expect = 1.648e-124
Identity = 64/144 (44.44%), Postives = 95/144 (65.97%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            KVL  LM Q+ SGK+ G++GRLG+L AI  KYDVA+S++C  LD+I+ + I+ AQKCV  +K   I  +TFIGL+K+  W +++        NIPR FD++ + +   R   YFA RD L+A ++E+A R   Q+  ++R+VTL
Sbjct:  597 KVLDTLMQQKRSGKIPGILGRLGDLGAIDEKYDVAISSSCGSLDNILVDTIDTAQKCVTFLKAQNIGVATFIGLDKMKVW-QQSMGSISTPENIPRLFDMVRVKDESVRPAFYFALRDTLVAKDLEQATRVAFQKDKRWRVVTL 739
[Close]
BLAST of Structural maintenance of chromosomes protein vs. TrEMBL
Match: A0A5K3FCD3 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 358.221 bits (918), Expect = 5.644e-124
Identity = 231/613 (37.68%), Postives = 352/613 (57.42%), Query Frame = 3 
Query:  936 VKGELIEVTGSMTGGG-SRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQ---------NNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPL-------PEGVEE--------DSEDTSFMDLIGESGDINIFSSQK------DSHSGTTLKVYSNEELLKFKNHQITYQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAVDCS 2681
            ++G+LIE +G+M+GGG +R + G++ TD     +   R  S+G F    TE S   KE+EL     ++    ++ E L++ +  T+ SQ            QN +  L  +     +E +  E +  +  P  K    +E+A+ +L+K +   + + D+L+  V ++   +   G A+L  ++SR+  ++++ +E      K+ + +K A++  AK    +++   E  + +E    ++A +  +EK A   + E+Q + + +  L +   + + EI +   NL   +       R  EE +  V +   R R  +  ++ L  + +         G +E        DS+ T     + E  D N  S+ +      D+   T L  ++ E+L +   ++   Q +E++ N   PN+AAIE+YR K +LY+ R AEL +VT+ R +Q  Q    K +R  EF AGFN+ITT+LKEMYQM+T GGDAELEL+DSLDPFSEGI+FSVRPPKK+WK+I+NLSGGEKTLSSLALVFALHH+KPTP YVMDEIDAALDFKNVSIV NY+ +RTKNAQF+IISLRNNM++LAD L+GI K  N TK+      A+DC+
Sbjct:  507 LQGQLIEASGAMSGGGGNRSISGRMTTDA----QRARRRSSTGLF----TEASIAEKEKELTTCETKLAATKQRRERLEDAV--TQLSQCMQEAQRKVTKCQNEIARLREEAAVLTREADQAEKRAASAGPTAKERQKMESAVANLEKLHAAKAEKADALRARVEEVKASLVGAGSARLAAVRSRVGLVEKKIKETNDQFTKLEVDIKSAQRNEAKCEAKVKSYEDEVERLKERLVTIEARMLEIEKTAKTCMDEFQDLQKSIHELNQNLAKVNCEIEQAESNLAAKRKDEGIAQRQAEELRGQVKEAASRARTWQMKLRSLRLHVIEEDEEEEAAGSQEADSQRASVDSDCTRPQSPVPE--DTNAPSTSRSPDSLGDASKRTKLPTFTEEQLAEMTVNEAEVQKLEEQTNAMAPNMAAIEQYRKKVDLYLKRVAELDQVTELRAEQLRQEADAKAKRLSEFMAGFNVITTRLKEMYQMLTQGGDAELELIDSLDPFSEGIVFSVRPPKKTWKSIANLSGGEKTLSSLALVFALHHYKPTPLYVMDEIDAALDFKNVSIVGNYVVERTKNAQFVIISLRNNMFDLADRLVGIYKTHNITKSV-----AIDCA 1102

HSP 2 Score: 118.627 bits (296), Expect = 5.644e-124
Identity = 68/179 (37.99%), Postives = 105/179 (58.66%), Query Frame = 2 
Query:  410 VDQLNHLLKSR-------QSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANI-NIPRAFDLLTIPNNDH-RAVLYFAFRDLLLANN----VEEARQTNQRAMKYRIVTLNVTFV 907
            +DQ+N L  S        Q+  T ++VLS L     +GKLKG++GRLG+L  I  KYD+A+ST+C  LD I+ E +  AQ+ VE +K + + +++FIGL+K+ +W  +A  +FV  +    R FDL+   +N   R   YFA R+ L+A+N    V+ A +  QR   +R+VTL    +
Sbjct:  337 IDQVNQLRSSLTEAKSSFQADSTRNRVLSALTTAMQAGKLKGILGRLGDLGVIPQKYDIAISTSCGALDHIVVETMEFAQRAVEYLKQNNLGQASFIGLDKMQRWASEATRRFVGPVPTAQRLFDLVDTSSNPQVRPCFYFALRNTLVADNLDIAVDWAFKHEQR---HRVVTLQGQLI 512
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Cavefish
Match: smc4 (structural maintenance of chromosomes 4 [Source:NCBI gene;Acc:103045898])

HSP 1 Score: 336.265 bits (861), Expect = 4.017e-123
Identity = 211/587 (35.95%), Postives = 324/587 (55.20%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQD---MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE +G+MTGGG R ++G++ + +                  + T++  DR E  LN+ + Q+    ++ + L+ ++   +    +++N L+      +  E++  +++ ++K  + +  A    +   + ++K +E  S +   ++ EV ++   I  +   KL   + +LD ++++  E +  + K  +A+K A +   K    ++ L  E  ++E+  +E+   LK LE++AG+ +   Q   E +  + +       EI  + E     +   + I    E+    + + + + +    +  K+  + +                              D      L   + E+L   KN  +   +   +ED+  + KPNL AI E++ KEELY+ R AEL E+T  RD  +   E +++QR  EF AGFN+IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHHFKPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E+AD LIGI K  N TK   +N K +
Sbjct:  600 WRVVTLQGQIIEQSGTMTGGGGRVMKGRMGSSIG----------------TEVTQEQLDRMESALNEKVVQLQGWQQRKQQLEEKVHKQRRELRDMKNTLEKYTASIQSLEEQEMLMKSQMKGLEANVLAAAPDKAKQKQMEKNFEAASNKAGKVEAEVKRLHTLIVDINSHKLKAQQDKLDKVNKELDECSSAITKAQVAIKTAGRNLKKSEEIVERLETETKENEKLMEELMEQLKKLEEQAGEIMKTCQDAEEALPEVQEEHRGVLQEIKAVQEKEHALQKESLNIRLKVEQIDTAISECQSKSKHWDKEATKIVLHSI------------------------------DDKPAEELPKLTPEDLAAIKNPDVIKNEIALLEDRCARMKPNLGAIAEFKKKEELYLQRVAELDEITTQRDDFKRGCEDLRKQRLNEFMAGFNIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIYNLSGGEKTLSSLALVFALHHFKPTPLYFMDEIDAALDFKNVSIVACYIYEQTKNAQFIIISLRNNMFEMADRLIGIYKTHNTTKNVGINPKTI 1140

HSP 2 Score: 127.487 bits (319), Expect = 4.017e-123
Identity = 66/153 (43.14%), Postives = 95/153 (62.09%), Query Frame = 2 
Query:  437 SRQSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            S  S  +  KVL  LM Q+ SGK+ G+ GRLG+L AI  +YDVA+S++C  LD+I+ + I+ AQKCV  +K   I  +TFIGL+K+  W K          NIPR FD++ + +   R   YFA RD L+A ++E+A R   Q+  ++R+VTL
Sbjct:  454 SLSSNRSRGKVLDALMQQKQSGKIPGIFGRLGDLGAIDERYDVAISSSCGSLDNILVDTIDTAQKCVVFLKSQNIGVATFIGLDKMKVWEKNMV-AISTPENIPRLFDMVKVKDESVRPAFYFALRDTLVAKDLEQATRVAFQKDKRWRVVTL 605
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Cavefish
Match: smc4 (structural maintenance of chromosomes 4 [Source:NCBI gene;Acc:103045898])

HSP 1 Score: 343.969 bits (881), Expect = 1.894e-100
Identity = 217/594 (36.53%), Postives = 324/594 (54.55%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLL-------KDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQD---MEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE +G+MTGGG R ++G++ + +                  + T++  DR E  LN+ + Q+    ++ + L+ ++   +    +++N L       + L   E   + ++  LE  + A  PD      +E ++ + KK +E  S +   ++ EV ++   I  +   KL   + +LD ++++  E +  + K  +A+K A +   K    ++ L  E  ++E+  +E+   LK LE++AG+ +   Q   E +  + +       EI  + E     +   + I    E+    + + + + +    +  K+  + +                              D      L   + E+L   KN  +   +   +ED+  + KPNL AI E++ KEELY+ R AEL E+T  RD  +   E +++QR  EF AGFN+IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHHFKPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E+AD LIGI K  N TK   +N K +
Sbjct:  742 WRVVTLQGQIIEQSGTMTGGGGRVMKGRMGSSIG----------------TEVTQEQLDRMESALNEKVVQLQGWQQRKQQLEEKVHKQRRELRDMKNTLEKYTASIQSLEEQEMLMKSQMKGLEANVLAAAPDKAKQKQMEKSLDAFKKNFEAASNKAGKVEAEVKRLHTLIVDINSHKLKAQQDKLDKVNKELDECSSAITKAQVAIKTAGRNLKKSEEIVERLETETKENEKLMEELMEQLKKLEEQAGEIMKTCQDAEEALPEVQEEHRGVLQEIKAVQEKEHALQKESLNIRLKVEQIDTAISECQSKSKHWDKEATKIVLHSI------------------------------DDKPAEELPKLTPEDLAAIKNPDVIKNEIALLEDRCARMKPNLGAIAEFKKKEELYLQRVAELDEITTQRDDFKRGCEDLRKQRLNEFMAGFNIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIYNLSGGEKTLSSLALVFALHHFKPTPLYFMDEIDAALDFKNVSIVACYIYEQTKNAQFIIISLRNNMFEMADRLIGIYKTHNTTKNVGINPKTI 1289

HSP 2 Score: 127.487 bits (319), Expect = 2.182e-29
Identity = 68/161 (42.24%), Postives = 98/161 (60.87%), Query Frame = 2 
Query:  437 SRQSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVA---NINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTLNVTFV 907
            S  S  +  KVL  LM Q+ SGK+ G+ GRLG+L AI  +YDVA+S++C  LD+I+ + I+ AQKCV  +K   I  +TFIGL+K+  W K      VA     NIPR FD++ + +   R   YFA RD L+A ++E+A R   Q+  ++R+VTL    +
Sbjct:  596 SLSSNRSRGKVLDALMQQKQSGKIPGIFGRLGDLGAIDERYDVAISSSCGSLDNILVDTIDTAQKCVVFLKSQNIGVATFIGLDKMKVWEK----NMVAISTPENIPRLFDMVKVKDESVRPAFYFALRDTLVAKDLEQATRVAFQKDKRWRVVTLQGQII 752
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Cavefish
Match: smc1b (structural maintenance of chromosomes 1B [Source:ZFIN;Acc:ZDB-GENE-091217-1])

HSP 1 Score: 133.265 bits (334), Expect = 3.637e-31
Identity = 84/293 (28.67%), Postives = 152/293 (51.88%), Query Frame = 3 
Query: 1932 LIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQI--------TYQDMEDKLNKQK---------------PNLAAIEEYRMKEELY--MLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSL---DPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTK-NAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAVDCSLQHVCNTEKLPHPM 2723
            L G   DI+      +S S  TL +Y  E  + F   Q+        T +++E++L   +               PNL A+E+ R   E +  +L A E + +   +  Q  + E++K +R   F+  F  ++  + ++Y+ +    D+ L ++ +    +P+ +GI ++   P K +  + NLSGGEK++++LALVFA+H F+P PF+V+DE+DAALD  N+  V +YI+++++ N Q I+ISL+   Y  +D L+G+   F+            DC    + + +  P+P+
Sbjct:  876 LSGTLDDISDVQLDSESQSTCTLDIYEREAQIVFDYKQLGDRLMSLTTEEEVEEQLATMREKVSSLDKLIQVSKTPNLKALEKMREVRESFHEVLSAFESSTIISKKCNQ--EFEQVKAKRFHLFSKCFEHVSVAVNQIYKQLCRN-DSALAILSAENPDEPYLDGISYNCVAPGKRFMAMDNLSGGEKSIAALALVFAIHSFRPAPFFVLDEVDAALDNTNIGKVTSYIREQSRENLQIIVISLKEEFYSRSDALLGVYSEFD------------DCMYSRLLSVDLTPYPL 1153
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Cavefish
Match: smc1a (structural maintenance of chromosomes 1A [Source:NCBI gene;Acc:103021942])

HSP 1 Score: 132.88 bits (333), Expect = 5.081e-31
Identity = 70/198 (35.35%), Postives = 119/198 (60.10%), Query Frame = 3 
Query: 2061 MEDKLNKQK--------PNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAE--LELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRT-KNAQFIIISLRNNMYELADCLIGI 2621
            ++ +LN+Q+        PN+ A+E+     + +   + E     +   + +   E++K++R   F   F  + T + E+Y+ ++    A+  L   +  +P+ +GI ++   P K ++ + NLSGGEKT+++LAL+FA+H +KP PF+V+DEIDAALD  N+  VANYIKD++ +N Q I+ISL+   Y  AD LIG+
Sbjct: 1005 LQQRLNEQQSILQRISAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNTCFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKDQSVQNFQAIVISLKEEFYTKADSLIGV 1202
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Cavefish
Match: smc1b (structural maintenance of chromosomes 1B [Source:ZFIN;Acc:ZDB-GENE-091217-1])

HSP 1 Score: 127.487 bits (319), Expect = 2.138e-29
Identity = 79/259 (30.50%), Postives = 141/259 (54.44%), Query Frame = 3 
Query: 1932 LIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQI--------TYQDMEDKLNKQK---------------PNLAAIEEYRMKEELY--MLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSL---DPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTK-NAQFIIISLRNNMYELADCLIGI 2621
            L G   DI+      +S S  TL +Y  E  + F   Q+        T +++E++L   +               PNL A+E+ R   E +  +L A E + +   +  Q  + E++K +R   F+  F  ++  + ++Y+ +    D+ L ++ +    +P+ +GI ++   P K +  + NLSGGEK++++LALVFA+H F+P PF+V+DE+DAALD  N+  V +YI+++++ N Q I+ISL+   Y  +D L+G+
Sbjct:  876 LSGTLDDISDVQLDSESQSTCTLDIYEREAQIVFDYKQLGDRLMSLTTEEEVEEQLATMREKVSSLDKLIQVSKTPNLKALEKMREVRESFHEVLSAFESSTIISKKCNQ--EFEQVKAKRFHLFSKCFEHVSVAVNQIYKQLCRN-DSALAILSAENPDEPYLDGISYNCVAPGKRFMAMDNLSGGEKSIAALALVFAIHSFRPAPFFVLDEVDAALDNTNIGKVTSYIREQSRENLQIIVISLKEEFYSRSDALLGV 1131
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008608.1 (pep scaffold:Pmarinus_7.0:GL477381:37203:71735:-1 gene:ENSPMAG00000007778.1 transcript:ENSPMAT00000008608.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 329.717 bits (844), Expect = 4.956e-121
Identity = 218/589 (37.01%), Postives = 328/589 (55.69%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKN-----HQITYQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G++IE +G+M+GGG+R ++G++ + V         +R     E K  E+S   ++ +      Q + L E+ ++L+  ++  K++   L   +K     E   + ++  LE  + A  PD   +  LE  ++  KK+YEK S R   ++ EV +I   I  +   +L   + ++D I++Q  E    + K  +A+K A++   K    L     E+ ++ +    ++  LK LE+ A + + E     E  + + +L+ E   E+  ++E  Q  +   + +    E+    + ++   ++    ++ K   + L E  E                                L    N EL + ++     ++I    +E+K  + KPNL AI +Y+ KEE+Y+ R +EL  +T  RD+ R   E +++ R QEF AGFN+IT KLKE YQM+T GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA Y+ ++TKNAQFIIISLRNNM+E++D LIGI K  N TK+  +N K +
Sbjct:  744 WRVVTLQGQVIETSGTMSGGGTRVMKGRMGSSVVSEVPQEEVER----MEHKLQEESAKMEQYQ-----QQRSQLEERVQTLQTSLRDMKYNLQKLSAGVKVQVEQEVSLKLQVKELEANVVAAAPDKNQLKKLEKTLEGFKKEYEKVSSRTGKIEAEVKRIHGLIMEITQGRLKAQQDKVDKINQQIDECVSDITKAQVALKTADRNLKKAEEALAKTEREQEENRQAIVRLNEELKSLEEAAAEIMKECTHAQERGKEVSELQRELMGELKALSEEEQGYQKEELAVRLKVEQFDTKISELNSMLKHFNKELSKFKLHVLDEEGE-----------------------------APVLPTLGNRELEELEDPVALANKIAI--LEEKTLQMKPNLGAISDYKKKEEIYLQRVSELDAITAQRDEFRHSYEDLRKSRLQEFMAGFNVITNKLKENYQMLTQGGDAELELVDSLDPFSEGIVFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVALYVYEQTKNAQFIIISLRNNMFEMSDRLIGIYKTNNTTKSVAINPKTI 1292

HSP 2 Score: 124.405 bits (311), Expect = 4.956e-121
Identity = 61/147 (41.50%), Postives = 89/147 (60.54%), Query Frame = 2 
Query:  455 TEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            + +KVL  LM+Q++ G L G+ GRLG+L AI  KYDVA+S+ C  LD+I+ + ++ AQ CV  +K H I  +TFIGL+K+  W             + R FDL+ + +   R   YF  RD L+ANN+E+A R   Q   ++R+VTL
Sbjct:  603 SRNKVLQLLMDQKNKGSLPGIYGRLGDLGAIEEKYDVAISSCCGALDNIVVDTMDTAQACVTYLKKHNIGSATFIGLDKMRVWEGTMKKSVQGPEGVLRLFDLVRVGDEAVRTAFYFTLRDTLVANNLEQASRVAFQHQRRWRVVTL 749
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000346.1 (pep scaffold:Pmarinus_7.0:GL477118:44770:74561:-1 gene:ENSPMAG00000000296.1 transcript:ENSPMAT00000000346.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 124.02 bits (310), Expect = 6.193e-29
Identity = 63/181 (34.81%), Postives = 110/181 (60.77%), Query Frame = 3 
Query: 2088 PNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELV--DSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRT-KNAQFIIISLRNNMYELADCLIGI 2621
            PN+ A E++      ++     L E  +   Q +    K++R R   F      ++  + ++Y+ +     A+  L   ++ +P+ +GI ++   P K ++ + NLSGGEKT+++LAL+FA+H ++P+PF+V+DEIDAALD  N+  VANYIK+++ +N Q I+ISL+  ++  AD LIG+
Sbjct: 1015 PNMKATEKFENVRGKFLETTEALEESRKRSKQAQMAFNKVQRLRFDRFNGCLEHLSIAIDDIYKKLAQNNSAQAFLGPENAEEPYLDGINYNCVAPGKRYQPMDNLSGGEKTVAALALLFAIHSYRPSPFFVLDEIDAALDNTNIGKVANYIKEQSVENFQVIVISLKEELFARADALIGV 1195
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Sea Lamprey
Match: SMC1A (structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111])

HSP 1 Score: 107.071 bits (266), Expect = 7.226e-24
Identity = 55/165 (33.33%), Postives = 100/165 (60.61%), Query Frame = 3 
Query: 2040 HQIT-YQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAE--LELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIV 2525
            H++T +Q++  +++   PN+ A+E+     + +   A E     +   + +   E++K++R   F A F  ++T + E+Y+ ++    A+  L   +  +P+ +GI ++   P K ++ + NLSGGEKT+++LAL+FA H +KP PF+V+DEIDAALD  N+S V
Sbjct:  639 HKVTEHQNIMQRISA--PNMRAMEKLESVRDKFQETADEFEAARKRAKKSKQAFEQIKKERFDRFNACFEAVSTNIDEIYKALSRNASAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFATHSYKPAPFFVLDEIDAALDNTNISKV 801
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Sea Lamprey
Match: smc2 (structural maintenance of chromosomes 2 [Source:ZFIN;Acc:ZDB-GENE-030131-105])

HSP 1 Score: 76.6406 bits (187), Expect = 1.917e-14
Identity = 31/79 (39.24%), Postives = 55/79 (69.62%), Query Frame = 3 
Query: 2379 WK-NISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCL 2612
            WK N+S LSGG+++L +L+L+ A+  FKP P Y++DE+DAALD  +   + + ++     +QF+++SL++ M+  A+ L
Sbjct: 1082 WKENLSELSGGQRSLVALSLILAMLLFKPAPIYILDEVDAALDLSHTQNIGHMLRTHFLTSQFVVVSLKDGMFNNANVL 1160
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Yeast
Match: SMC4 (Subunit of the condensin complex; condensin reorganizes chromosomes during both mitosis and meiosis; forms a subcomplex with Smc2p that has ATP-hydrolyzing and DNA-binding activity, but other condensin subunits are required for chromatin binding; required for tRNA gene clustering at the nucleolus; potential Cdc28p substrate [Source:SGD;Acc:S000004076])

HSP 1 Score: 271.937 bits (694), Expect = 4.143e-76
Identity = 131/213 (61.50%), Postives = 165/213 (77.46%), Query Frame = 3 
Query: 2019 ELLKFKNHQITYQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLL 2657
            EL++ K ++++Y   E  ++     +  +EEY  +   +  R  +L    Q RD+ ++QL  +K++R  EF AGFN+I+  LKEMYQMITMGG+AELELVDSLDPFSEG+ FSV PPKKSW+NI+NLSGGEKTLSSLALVFALH +KPTP YVMDEIDAALDF+NVSIVANYIK+RTKNAQFI+ISLRNNM+ELA  L+G+ K  N TK+  +
Sbjct: 1202 ELIESKINELSYYVEETNVD-----IGVLEEYARRLAEFKRRKLDLNNAVQKRDEVKEQLGILKKKRFDEFMAGFNIISMTLKEMYQMITMGGNAELELVDSLDPFSEGVTFSVMPPKKSWRNITNLSGGEKTLSSLALVFALHKYKPTPLYVMDEIDAALDFRNVSIVANYIKERTKNAQFIVISLRNNMFELAQQLVGVYKRDNRTKSTTI 1409

HSP 2 Score: 96.2857 bits (238), Expect = 1.335e-20
Identity = 49/148 (33.11%), Postives = 83/148 (56.08%), Query Frame = 2 
Query:  464 KVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEARQTNQRAMKYRIVTLNVTFV 907
            KVL+ L   Q SG++ G  GRLG+L  I   +DVA+STAC RLD ++ + +  AQ C++ ++ +K+  + FI L+++ Q+  +         N+PR FDL+   N       Y   RD L+A N+++A        ++R+VT++   +
Sbjct:  671 KVLTALSRLQKSGRINGFHGRLGDLGVIDDSFDVAISTACPRLDDVVVDTVECAQHCIDYLRKNKLGYARFILLDRLRQFNLQP---ISTPENVPRLFDLVKPKNPKFSNAFYSVLRDTLVAQNLKQANNVAYGKKRFRVVTVDGKLI 815
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Yeast
Match: SMC1 (Subunit of the multiprotein cohesin complex; essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure [Source:SGD;Acc:S000001886])

HSP 1 Score: 144.05 bits (362), Expect = 2.339e-35
Identity = 73/199 (36.68%), Postives = 124/199 (62.31%), Query Frame = 3 
Query: 2055 QDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMIT---------MGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYI-KDRTKNAQFIIISLRNNMYELADCLIGI 2621
             ++E+ LN+ +PN  A+E Y   E  + +   E  ++     +  +Q  K+K++R + F   F+ ++  L  +Y+ +T          GG+A L + D  +PF+ GI +   PP K +K++  LSGGEKT+++LAL+FA++ ++P+PF+V+DE+DAALD  NV  +A YI + R  + QFI+ISL+N M+E +D L+G+
Sbjct: 1006 HEVEEILNELQPNARALERYDEAEGRFEVINNETEQLKAEEKKILNQFLKIKKKRKELFEKTFDYVSDHLDAIYRELTKNPNSNVELAGGNASLTIEDEDEPFNAGIKYHATPPLKRFKDMEYLSGGEKTVAALALLFAINSYQPSPFFVLDEVDAALDITNVQRIAAYIRRHRNPDLQFIVISLKNTMFEKSDALVGV 1204
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Yeast
Match: SMC2 (Subunit of the condensin complex; condensin reorganizes chromosomes during both mitosis and meiosis; essential SMC chromosomal ATPase family member that forms a subcomplex with Smc2p that has ATP-hydrolyzing and DNA-binding activity, but other condensin subunits are required for chromatin binding; required for clustering of tRNA genes at the nucleolus [Source:SGD;Acc:S000001927])

HSP 1 Score: 80.1073 bits (196), Expect = 1.216e-15
Identity = 33/77 (42.86%), Postives = 54/77 (70.13%), Query Frame = 3 
Query: 2379 WK-NISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELAD 2606
            WK ++  LSGG+++L +L+L+ AL  F+P P Y++DE+DAALD  +   + + IK R K +QFI++SL+  M+  A+
Sbjct: 1077 WKESLIELSGGQRSLIALSLIMALLQFRPAPMYILDEVDAALDLSHTQNIGHLIKTRFKGSQFIVVSLKEGMFANAN 1153
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Yeast
Match: SMC3 (Subunit of the multiprotein cohesin complex; required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member [Source:SGD;Acc:S000003610])

HSP 1 Score: 75.0998 bits (183), Expect = 4.177e-14
Identity = 55/184 (29.89%), Postives = 93/184 (50.54%), Query Frame = 3 
Query: 2142 RAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAEL-------------ELVD-SLDPFSE-------------GILFSVRPPKKSWK--NISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELAD 2606
            RA+EL E    +D  +D + K+K+Q+     + F  ++   + +++ +   G A+L             E +D  +D  S              G+  SV    K  +  ++  LSGG+KT+ ++AL+ A+    P  FY+ DEIDAALD +  + VA  +K+ +KNAQFI  + R +M ++AD
Sbjct: 1015 RASELDES---KDSIQDLIVKLKQQKVNAVDSTFQKVSENFEAVFERLVPRGTAKLIIHRKNDNANDHDESIDVDMDAESNESQNGKDSEIMYTGVSISVSFNSKQNEQLHVEQLSGGQKTVCAIALILAIQMVDPASFYLFDEIDAALDKQYRTAVATLLKELSKNAQFICTTFRTDMLQVAD 1195
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Nematostella
Match: EDO40646 (Structural maintenance of chromosomes protein [Source:UniProtKB/TrEMBL;Acc:A7S6N1])

HSP 1 Score: 365.925 bits (938), Expect = 4.119e-109
Identity = 246/598 (41.14%), Postives = 358/598 (59.87%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICT----DVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQ----INNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKL--TFYPLPEGVEEDSEDTSFMDL--IGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQ--DMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   +G LI+ +G+M+GGG+R  +G++C+    DV+  Q  +   +     E K+TE+ R++K+Q L + +++    ++NL  + E  KNR++    S+   Q  L D          ++  ++ +++   PD K V  LET +   +K+++K +     ++ EV  +  +I  +G AKL   +SRLDA  +   E  G + K ++ +K A +   K    + +L  E  ++    K+++   K LE++A   L  Y+              +  V + ++ E L+K+K       +D+   +A   Q+K +   +K +++K    F    + V    ++ S ++L  +G S          D      L   S E+L       + Y+   +E+KL + KPN+AAI EYR KEE Y+ R  EL +VT  RD +R + E ++++R  EF AGF++ITTKLKEMYQMIT+GGDAELELVDSLDPFSEGI+FSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTP YVMDEIDAALDF+NVSIVANYIK+RTKNAQFIIISLRNNM+ELAD LIGI K ++ TK+  +N K +
Sbjct:  668 WRVVTLQGSLIDQSGTMSGGGTRVAKGRMCSSFVSDVSPQQLKSMEQKLEQ--EEKATEEYREQKKQ-LEEAVDEQKKKVSNLEHQLE--KNRMEVQALSEQ--QQALND----------QIKHIKQEVEKTTPDEKRVKELETVVAKHEKEWKKAAAAASKIEAEVQSLHRQIMDIGGAKLKGQQSRLDAATKACDEVQGQITKASVGIKTANRNIQKSEEKVASLEKEVEENACYLKKLEDDFKRLEEEATQVLKAYE--------------DAQVHMKEMEEALEKTK-------QDYAVIEAEEVQLKNKEVDLKHEVEKYETVFKENQQKVRHWQKELSKLELQCVGIS----------DEQQKEELPKLSTEDLEAVDKEAVMYEITVLEEKLAQLKPNMAAIAEYRKKEEAYLARVGELDQVTSDRDNKRKEHEALRKKRLDEFMAGFSIITTKLKEMYQMITLGGDAELELVDSLDPFSEGIVFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPLYVMDEIDAALDFRNVSIVANYIKERTKNAQFIIISLRNNMFELADRLIGIYKTYDCTKSVAINPKLI 1217

HSP 2 Score: 127.872 bits (320), Expect = 6.297e-30
Identity = 64/158 (40.51%), Postives = 98/158 (62.03%), Query Frame = 2 
Query:  437 SRQSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTLNVTFV 907
            S Q+  +   VL  LM Q+++GK+ G+ GRLG+L AI  KYD+A+STAC  LD I+ + +  AQ CV+ +K + I  +TFIGL+KV  W K A+ K     N+PR +DL+ + +       YFA R+ L+A+ +E+A R   Q   ++R+VTL  + +
Sbjct:  521 SLQASRSRGNVLEALMKQKAAGKIPGLYGRLGDLGAIDDKYDIAISTACGALDHIVCDTMETAQTCVQYLKKNNIGAATFIGLDKVEVWRKDASSKIQTPSNVPRLYDLVRVKDAKVSTAFYFALRNTLVADELEQATRIAFQGNKRWRVVTLQGSLI 678
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Nematostella
Match: EDO49596 (Structural maintenance of chromosomes protein [Source:UniProtKB/TrEMBL;Acc:A7RFF3])

HSP 1 Score: 124.79 bits (312), Expect = 6.447e-29
Identity = 64/183 (34.97%), Postives = 111/183 (60.66%), Query Frame = 3 
Query: 2082 QKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELV--DSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNA-QFIIISLRNNMYELADCLIGI 2621
            Q PN+ A+E+       +     E  +      + + + E +K++R+  F + F  ++TK+ ++Y+ +     A+  L   D+ +P+  GI ++   P K ++ + NLSGGEKT+++LAL+F++H ++P PF+V+DEIDAALD  N++ VA +I ++TK   Q I+ISL+   Y  A+ LIGI
Sbjct: 1011 QAPNMKALEKLEGASSRFQETNNEFEQARSRARKAKIEFETVKKERYDRFMSAFEHVSTKIDDIYKELANNPSAQAFLGPEDAEEPYLGGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFSIHSYQPAPFFVLDEIDAALDNTNINKVARHIINQTKEYFQCIVISLKEEFYTRAEALIGI 1193
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Nematostella
Match: EDO27517 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T917])

HSP 1 Score: 85.5001 bits (210), Expect = 6.308e-19
Identity = 39/76 (51.32%), Postives = 55/76 (72.37%), Query Frame = 2 
Query:  467 VLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKV 694
            VL  LM Q+++GK+ G+ GRLG+L AI  KYD+A+STAC  LD I+ + +  AQ CV+ +K + I  +TFIGL+KV
Sbjct:  126 VLEALMKQKAAGKIPGLYGRLGDLGAIDDKYDIAISTACGALDHIVCDTMETAQTCVQYLKKNNIGAATFIGLDKV 201
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Nematostella
Match: EDO34135 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQ79])

HSP 1 Score: 68.5514 bits (166), Expect = 4.387e-14
Identity = 34/78 (43.59%), Postives = 48/78 (61.54%), Query Frame = 3 
Query: 2388 ISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGI 2621
            ++ LSGG+K+L +LAL+FA+    P PFY+ DEID ALD +    VA  I++    AQFI  + R  + E AD   G+
Sbjct:    1 MNQLSGGQKSLVALALIFAIQKCDPAPFYLFDEIDQALDPQFRKAVAEMIRNLAVKAQFITTTFRPELLESADKFYGV 78
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Medaka
Match: smc4 (structural maintenance of chromosomes 4 [Source:NCBI gene;Acc:101157474])

HSP 1 Score: 330.102 bits (845), Expect = 1.069e-119
Identity = 219/591 (37.06%), Postives = 333/591 (56.35%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEK-------AESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   KG++IE+ G+MTGGG R ++G++ + +            S +F    ++   DR E +LN+ +++++   EK        + L+ +++  K +     N +  L   E     ++  LE  + A  PD      +E ++++ KK YE  S +   ++ EV ++   I  +   KL   + +LD I+++  E +  + K  +A+K A++   K    +  L  E  ++E+   ++   LK +E +AG+ +   Q+    +  + +  ++ S EI  + +     +   + +    E+  A + +   +I+  +D+  KL+ + + EG  + +E    +                   +   LK  S+   +  K        +E + +  KPNL AI EY+ KEELY+ R A+L E+T  RD  +   E ++++R  EF  GFN+IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E+AD LIGI K  N TK+  +N K +
Sbjct:  740 WRVVTLKGQIIEMAGTMTGGG-RIMKGRMGSSI------------STDF----SQAELDRMESKLNEKVSKLHGCQEKKLQVEESVQRLQPQLREMKNTFEKYTNSITSLADQETHLVLQIKELEANVLAAAPDKNKQKQMEKSLENFKKDYESASSKAGKVENEVKRLHNLIVDINSHKLKAQQDKLDKINKELDECSSIITKAKVAIKTADRNLKKCEESVAHLQSELEENEKLMTDLTEQLKKVEDEAGEIMKACQEAEAALPEVQEQYQKVSKEIKILQQQEHALQEESLNVRLSIEQIDATITKHNGKIKHWQDEASKLSLHVI-EG--QPNEKLPVL-------------------AAAELKAISDPNAIVNK-----MSTLEIQCSHLKPNLGAISEYKKKEELYLQRVAQLDEITAERDTFKCSYEDLRKRRLNEFMTGFNMITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVACYIYEQTKNAQFIIISLRNNMFEIADRLIGIYKTHNTTKSVGINPKTI 1286

HSP 2 Score: 122.094 bits (305), Expect = 1.069e-119
Identity = 67/166 (40.36%), Postives = 102/166 (61.45%), Query Frame = 2 
Query:  410 VDQLNHLLKSRQSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANI----NIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            VD+    L S +S+    KVL  LM  + +G++ G+ GRLG+L AI  KYDVA+S+ C  LD+I+ + I+ AQKCV  +K   I  +TFIGL+K+  W     +K +A I    + PR FD++ + ++  R   YFA RD L+A ++E+A R   Q+  ++R+VTL
Sbjct:  588 VDEAKTSLSSNRSR---GKVLDALMQLKKTGRIPGIYGRLGDLGAIDEKYDVAISSCCGALDNIVVDTIDTAQKCVTFLKEQNIGVATFIGLDKMKTW-----EKNMAPIRTPEDSPRLFDMVRVNDDSVRPAFYFALRDTLVAQDMEQATRMAFQKEKRWRVVTL 745
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Medaka
Match: smc4 (structural maintenance of chromosomes 4 [Source:NCBI gene;Acc:101157474])

HSP 1 Score: 330.102 bits (845), Expect = 1.069e-119
Identity = 219/591 (37.06%), Postives = 333/591 (56.35%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEK-------AESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   KG++IE+ G+MTGGG R ++G++ + +            S +F    ++   DR E +LN+ +++++   EK        + L+ +++  K +     N +  L   E     ++  LE  + A  PD      +E ++++ KK YE  S +   ++ EV ++   I  +   KL   + +LD I+++  E +  + K  +A+K A++   K    +  L  E  ++E+   ++   LK +E +AG+ +   Q+    +  + +  ++ S EI  + +     +   + +    E+  A + +   +I+  +D+  KL+ + + EG  + +E    +                   +   LK  S+   +  K        +E + +  KPNL AI EY+ KEELY+ R A+L E+T  RD  +   E ++++R  EF  GFN+IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E+AD LIGI K  N TK+  +N K +
Sbjct:  740 WRVVTLKGQIIEMAGTMTGGG-RIMKGRMGSSI------------STDF----SQAELDRMESKLNEKVSKLHGCQEKKLQVEESVQRLQPQLREMKNTFEKYTNSITSLADQETHLVLQIKELEANVLAAAPDKNKQKQMEKSLENFKKDYESASSKAGKVENEVKRLHNLIVDINSHKLKAQQDKLDKINKELDECSSIITKAKVAIKTADRNLKKCEESVAHLQSELEENEKLMTDLTEQLKKVEDEAGEIMKACQEAEAALPEVQEQYQKVSKEIKILQQQEHALQEESLNVRLSIEQIDATITKHNGKIKHWQDEASKLSLHVI-EG--QPNEKLPVL-------------------AAAELKAISDPNAIVNK-----MSTLEIQCSHLKPNLGAISEYKKKEELYLQRVAQLDEITAERDTFKCSYEDLRKRRLNEFMTGFNMITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVACYIYEQTKNAQFIIISLRNNMFEIADRLIGIYKTHNTTKSVGINPKTI 1286

HSP 2 Score: 122.094 bits (305), Expect = 1.069e-119
Identity = 67/166 (40.36%), Postives = 102/166 (61.45%), Query Frame = 2 
Query:  410 VDQLNHLLKSRQSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANI----NIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            VD+    L S +S+    KVL  LM  + +G++ G+ GRLG+L AI  KYDVA+S+ C  LD+I+ + I+ AQKCV  +K   I  +TFIGL+K+  W     +K +A I    + PR FD++ + ++  R   YFA RD L+A ++E+A R   Q+  ++R+VTL
Sbjct:  588 VDEAKTSLSSNRSR---GKVLDALMQLKKTGRIPGIYGRLGDLGAIDEKYDVAISSCCGALDNIVVDTIDTAQKCVTFLKEQNIGVATFIGLDKMKTW-----EKNMAPIRTPEDSPRLFDMVRVNDDSVRPAFYFALRDTLVAQDMEQATRMAFQKEKRWRVVTL 745
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Medaka
Match: smc4 (structural maintenance of chromosomes 4 [Source:NCBI gene;Acc:101157474])

HSP 1 Score: 310.071 bits (793), Expect = 1.146e-113
Identity = 218/593 (36.76%), Postives = 324/593 (54.64%), Query Frame = 3 
Query:  930 YRV---KGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLA---------EYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAV 2672
            +RV   KG++IE+ G+MTGGG R ++G++ + +            S +F                            +AESL ++       + +L   +K+L         E N+L     A  PD      +E ++++ KK YE  S +   ++ EV ++   I  +   KL   + +LD I+++  E +  + K  +A+K A++   K    +  L  E  ++E+   ++   LK +E +AG+ +          +YQK+S            + ++I +  E+  + + +++++S   E+  A + +   +I+  +D+  KL+ + + EG  + +E    +                   +   LK  S+   +  K        +E + +  KPNL AI EY+ KEELY+ R A+L E+T  RD  +   E ++++R  EF  GFN+IT KLKE YQM+T+GGDAELELVDSLDPFSEGI+FSVRPPKKSWK I NLSGGEKTLSSLALVFALHH+KPTP Y MDEIDAALDFKNVSIVA YI ++TKNAQFIIISLRNNM+E+AD LIGI K  N TK+  +N K +
Sbjct:  718 WRVVTLKGQIIEMAGTMTGGG-RIMKGRMGSSI------------STDF---------------------------SQAESLADQ-------ETHLVLQIKEL---------EANVL-----AAAPDKNKQKQMEKSLENFKKDYESASSKAGKVENEVKRLHNLIVDINSHKLKAQQDKLDKINKELDECSSIITKAKVAIKTADRNLKKCEESVAHLQSELEENEKLMTDLTEQLKKVEDEAGEIMKACQEAEVSEQYQKVS------------KEIKILQQQEHALQEESLNVRLS--IEQIDATITKHNGKIKHWQDEASKLSLHVI-EG--QPNEKLPVL-------------------AAAELKAISDPNAIVNK-----MSTLEIQCSHLKPNLGAISEYKKKEELYLQRVAQLDEITAERDTFKCSYEDLRKRRLNEFMTGFNMITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVACYIYEQTKNAQFIIISLRNNMFEIADRLIGIYKTHNTTKSVGINPKTI 1208

HSP 2 Score: 122.094 bits (305), Expect = 1.146e-113
Identity = 67/166 (40.36%), Postives = 102/166 (61.45%), Query Frame = 2 
Query:  410 VDQLNHLLKSRQSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANI----NIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEA-RQTNQRAMKYRIVTL 892
            VD+    L S +S+    KVL  LM  + +G++ G+ GRLG+L AI  KYDVA+S+ C  LD+I+ + I+ AQKCV  +K   I  +TFIGL+K+  W     +K +A I    + PR FD++ + ++  R   YFA RD L+A ++E+A R   Q+  ++R+VTL
Sbjct:  566 VDEAKTSLSSNRSR---GKVLDALMQLKKTGRIPGIYGRLGDLGAIDEKYDVAISSCCGALDNIVVDTIDTAQKCVTFLKEQNIGVATFIGLDKMKTW-----EKNMAPIRTPEDSPRLFDMVRVNDDSVRPAFYFALRDTLVAQDMEQATRMAFQKEKRWRVVTL 723
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Medaka
Match: smc1al (structural maintenance of chromosomes 1A [Source:NCBI gene;Acc:100049244])

HSP 1 Score: 132.88 bits (333), Expect = 4.879e-31
Identity = 70/198 (35.35%), Postives = 119/198 (60.10%), Query Frame = 3 
Query: 2061 MEDKLNKQK--------PNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAE--LELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRT-KNAQFIIISLRNNMYELADCLIGI 2621
            ++ +LN+Q+        PN+ A+E+     + +   + E     +   + +   E++K++R   F   F  + T + E+Y+ ++    A+  L   +  +P+ +GI ++   P K ++ + NLSGGEKT+++LAL+FA+H +KP PF+V+DEIDAALD  N+  VANYIKD++ +N Q I+ISL+   Y  AD LIG+
Sbjct: 1005 LQQRLNEQQSILQRISAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNTCFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKDQSVQNFQAIVISLKEEFYTKADSLIGV 1202
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Medaka
Match: smc1b (meiosis-specific cohesin subunit SMC1 beta [Source:NCBI gene;Acc:100049500])

HSP 1 Score: 88.9669 bits (219), Expect = 1.683e-17
Identity = 58/220 (26.36%), Postives = 111/220 (50.45%), Query Frame = 3 
Query: 2076 NKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSL--DPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNA-QFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAVDCSLQHVCNTEKLPHPMI 2726
            N   PNL A+E+ R  ++ +          T+   +   + E++K QR   F+     ++  + ++Y+ I     A+  L      +P+  GI ++   P K + ++ NLSGGEK +++LA +FA+  F P PF V+DE+DAALD  N+  V ++I+++++ + Q I IS +   +  +D L+G+    +            +C    +   +  P+P++
Sbjct: 1019 NTTAPNLKALEKMREVKDKWQEVTDAFDLSTKAARKCSLEFEQVKAQRFHRFSRCLEHVSVVIDQIYKRICKNSSAQAILTAECADEPYLGGINYNCVAPGKRFMSMDNLSGGEKAIAALAFLFAVQSFCPAPFLVLDEVDAALDNSNIGKVTSFIREQSRQSMQVIAISHKQEFFSRSDGLLGVYSDVD------------ECMFSRILTLDLRPYPLV 1226
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Planmine SMEST
Match: SMESG000036986.1 (SMESG000036986.1)

HSP 1 Score: 1186.4 bits (3068), Expect = 0.000e+0
Identity = 610/619 (98.55%), Postives = 611/619 (98.71%), Query Frame = 3 
Query:  921 ATAYRV---KGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLXXXXXXXXXXXXSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSXXXXXXXXXXXXXSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAVDCSLQHVCNTEKLPHPMILNPASQAASQEKSP 2768
            A  YR+    GELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLET IQSLKKKYEKDSVRVDSLKEEVNKIIEEIKSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSEEVQVLVKLKEEQSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAVDCSLQHVCNTEKLPH MILNPASQAASQEKSP
Sbjct:  686 AMKYRIVTLNGELIEVTGSMTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELNDVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNILEGKLKANKPDPKAVILLETTIQSLKKKYEKDSVRVDSLKEEVNKIIEEIKSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDLQTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSEEVQVLVKLKEEQSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKKLTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNEELLKFKNHQITYQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAVDCSLQHVCNTEKLPHSMILNPASQAASQEKSP 1304

HSP 2 Score: 396.741 bits (1018), Expect = 1.754e-119
Identity = 210/216 (97.22%), Postives = 212/216 (98.15%), Query Frame = 2 
Query:  260 RLKLTRQNIIGNKEHYDSNIKEIPIMENEYRXXXXXXXXXXXXXXXXXXXVDQLNHLLKSRQSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEARQTNQRAMKYRIVTLNVTFV 907
            RLKLTRQNIIGNKEHYDSNIKEIPIMENEYR ITEEIAKLKEIEKKLKSEVDQLNHLLKSRQSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVAN+NIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEARQTNQRAMKYRIVTLN   +
Sbjct:  484 RLKLTRQNIIGNKEHYDSNIKEIPIMENEYRNITEEIAKLKEIEKKLKSEVDQLNHLLKSRQSKETEHKVLSFLMNQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKCVELMKLHKIARSTFIGLNKVIQWTKKANDKFVANVNIPRAFDLLTIPNNDHRAVLYFAFRDLLLANNVEEARQTNQRAMKYRIVTLNGELI 699
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Planmine SMEST
Match: SMESG000022017.1 (SMESG000022017.1)

HSP 1 Score: 126.716 bits (317), Expect = 3.437e-29
Identity = 80/219 (36.53%), Postives = 122/219 (55.71%), Query Frame = 3 
Query: 2082 QKPNLAAIEEYRMKEELYMLRAAELTEVTQFRDQQ------RDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITM--GGDAELELVDSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKN-AQFIIISLRNNMYELADCLIGINKPFNFTKTCLLNLKAVDCSLQHVCNTEKL 2711
            Q PNL A ++    EE   LR  E    TQF D +      +   EK+KR R+  F   FN++   +  +Y+ +    G  A L   +  +P+ + I F    P K ++++ +LSGGEKT+++LAL+FA H++ P+PF+V+DEIDAALD  N+  VA++I++   + AQ I+ISL+   Y  AD LIGI    + T + LL  K     L    + E+L
Sbjct: 1033 QTPNLRAGDKLDSVEE--RLRQTE----TQFEDTRHRARKAKMDFEKVKRCRYDRFMNCFNVVVDHIDGIYKNLARNPGAQASLLPTNHEEPYLDEIQFQCVAPGKRFQHMDSLSGGEKTIAALALLFATHNYNPSPFFVLDEIDAALDNTNIGKVASFIREYASDRAQIIVISLKEEFYSRADALIGI---MHTTDSNLLVSKVYRLDLSQYTDAEEL 1242
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Planmine SMEST
Match: SMESG000017173.1 (SMESG000017173.1)

HSP 1 Score: 83.9593 bits (206), Expect = 4.025e-16
Identity = 49/164 (29.88%), Postives = 83/164 (50.61%), Query Frame = 3 
Query: 2190 DQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELEL-------------------VDSLDPFSE-GILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGI 2621
            D ++ +  Q+++     F  ++   +E+++ +   G AEL +                   +  ++ F+  GI  S        K+++ LSGG+K+L +L L+FA+    P PFY+ DEIDAALD +    VA+ IK  +K+AQFI  + R  M E A+   G+
Sbjct:  723 DLMKALDHQKYEAIVLTFKQVSHYFQEIFKKLVPDGRAELIIRKGKHDDTLLDDEEDPSSSIPEVERFTGVGIEVSFTGGDAQMKDMNQLSGGQKSLVALTLIFAIQKCDPAPFYLFDEIDAALDPQYRKAVADMIKGLSKDAQFITTTFRPEMLEAAERFYGV 886
[Close]
BLAST of Structural maintenance of chromosomes protein vs. Planmine SMEST
Match: SMESG000017173.1 (SMESG000017173.1)

HSP 1 Score: 83.9593 bits (206), Expect = 4.302e-16
Identity = 49/164 (29.88%), Postives = 83/164 (50.61%), Query Frame = 3 
Query: 2190 DQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELEL-------------------VDSLDPFSE-GILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTPFYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIGI 2621
            D ++ +  Q+++     F  ++   +E+++ +   G AEL +                   +  ++ F+  GI  S        K+++ LSGG+K+L +L L+FA+    P PFY+ DEIDAALD +    VA+ IK  +K+AQFI  + R  M E A+   G+
Sbjct:  733 DLMKALDHQKYEAIVLTFKQVSHYFQEIFKKLVPDGRAELIIRKGKHDDTLLDDEEDPSSSIPEVERFTGVGIEVSFTGGDAQMKDMNQLSGGQKSLVALTLIFAIQKCDPAPFYLFDEIDAALDPQYRKAVADMIKGLSKDAQFITTTFRPEMLEAAERFYGV 896
The following BLAST results are available for this feature:
BLAST of Structural maintenance of chromosomes protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SMC41.089e-12237.97structural maintenance of chromosomes 4 [Source:HG... [more]
SMC41.089e-12237.97structural maintenance of chromosomes 4 [Source:HG... [more]
SMC41.445e-12237.97structural maintenance of chromosomes 4 [Source:HG... [more]
SMC49.202e-11335.51structural maintenance of chromosomes 4 [Source:HG... [more]
SMC1A1.141e-3035.86structural maintenance of chromosomes 1A [Source:H... [more]
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BLAST of Structural maintenance of chromosomes protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dpy-279.453e-5149.29Chromosome condensation protein dpy-27 [Source:Un... [more]
him-14.037e-2839.24Structural maintenance of chromosomes protein 1 [... [more]
him-11.086e-2445.87Structural maintenance of chromosomes protein 1 [... [more]
mix-12.978e-1344.44Mitotic chromosome and X-chromosome-associated pro... [more]
smc-34.051e-1337.50Structural maintenance of chromosomes protein 3 [... [more]
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BLAST of Structural maintenance of chromosomes protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
glu1.310e-7663.32gene:FBgn0015391 transcript:FBtr0080935[more]
SMC16.818e-2934.16gene:FBgn0040283 transcript:FBtr0084541[more]
SMC37.361e-1535.14gene:FBgn0015615 transcript:FBtr0074290[more]
SMC22.063e-1440.00gene:FBgn0027783 transcript:FBtr0087461[more]
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BLAST of Structural maintenance of chromosomes protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
smc41.195e-12737.31structural maintenance of chromosomes 4 [Source:ZF... [more]
smc1a1.547e-3135.86structural maintenance of chromosomes 1A [Source:Z... [more]
smc1al2.377e-3135.86structural maintenance of chromosomes 1A, like [So... [more]
smc1al3.114e-3135.86structural maintenance of chromosomes 1A, like [So... [more]
smc1b6.143e-2830.41structural maintenance of chromosomes 1B [Source:Z... [more]
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BLAST of Structural maintenance of chromosomes protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SMC44.477e-12337.94structural maintenance of chromosomes 4 [Source:NC... [more]
SMC46.296e-12337.94structural maintenance of chromosomes 4 [Source:NC... [more]
SMC48.079e-12337.94structural maintenance of chromosomes 4 [Source:NC... [more]
SMC41.471e-12137.69structural maintenance of chromosomes 4 [Source:NC... [more]
SMC41.547e-12137.69structural maintenance of chromosomes 4 [Source:NC... [more]
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BLAST of Structural maintenance of chromosomes protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Smc41.365e-12337.35structural maintenance of chromosomes 4 [Source:MG... [more]
Smc41.695e-12337.35structural maintenance of chromosomes 4 [Source:MG... [more]
Smc1a8.747e-3135.86structural maintenance of chromosomes 1A [Source:M... [more]
Smc1b1.534e-2834.81structural maintenance of chromosomes 1B [Source:M... [more]
Smc42.989e-1846.75structural maintenance of chromosomes 4 [Source:MG... [more]
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BLAST of Structural maintenance of chromosomes protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9ERA5|SMC4_MICAR2.684e-12438.22Structural maintenance of chromosomes protein 4 (F... [more]
sp|Q8CG47|SMC4_MOUSE1.033e-12237.35Structural maintenance of chromosomes protein 4 OS... [more]
sp|Q9NTJ3|SMC4_HUMAN4.812e-12237.97Structural maintenance of chromosomes protein 4 OS... [more]
sp|P50532|SMC4_XENLA5.635e-12238.11Structural maintenance of chromosomes protein 4 OS... [more]
sp|Q9FJL0|SMC4_ARATH3.435e-8734.86Structural maintenance of chromosomes protein 4 OS... [more]
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BLAST of Structural maintenance of chromosomes protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3M6TVW61.598e-13439.80Structural maintenance of chromosomes protein OS=P... [more]
C3YK101.626e-12839.79SMC hinge domain-containing protein OS=Branchiosto... [more]
A0A0N7ZBS81.248e-12739.34Structural maintenance of chromosomes protein OS=S... [more]
E7FGC21.648e-12437.31Structural maintenance of chromosomes protein OS=D... [more]
A0A5K3FCD35.644e-12437.68Uncharacterized protein OS=Mesocestoides corti OX=... [more]
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BLAST of Structural maintenance of chromosomes protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
smc44.017e-12335.95structural maintenance of chromosomes 4 [Source:NC... [more]
smc41.894e-10036.53structural maintenance of chromosomes 4 [Source:NC... [more]
smc1b3.637e-3128.67structural maintenance of chromosomes 1B [Source:Z... [more]
smc1a5.081e-3135.35structural maintenance of chromosomes 1A [Source:N... [more]
smc1b2.138e-2930.50structural maintenance of chromosomes 1B [Source:Z... [more]
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BLAST of Structural maintenance of chromosomes protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000008608.14.956e-12137.01pep scaffold:Pmarinus_7.0:GL477381:37203:71735:-1 ... [more]
ENSPMAT00000000346.16.193e-2934.81pep scaffold:Pmarinus_7.0:GL477118:44770:74561:-1 ... [more]
SMC1A7.226e-2433.33structural maintenance of chromosomes 1A [Source:H... [more]
smc21.917e-1439.24structural maintenance of chromosomes 2 [Source:ZF... [more]
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BLAST of Structural maintenance of chromosomes protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4
Match NameE-valueIdentityDescription
SMC44.143e-7661.50Subunit of the condensin complex; condensin reorga... [more]
SMC12.339e-3536.68Subunit of the multiprotein cohesin complex; essen... [more]
SMC21.216e-1542.86Subunit of the condensin complex; condensin reorga... [more]
SMC34.177e-1429.89Subunit of the multiprotein cohesin complex; requi... [more]
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BLAST of Structural maintenance of chromosomes protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO406464.119e-10941.14Structural maintenance of chromosomes protein [So... [more]
EDO495966.447e-2934.97Structural maintenance of chromosomes protein [So... [more]
EDO275176.308e-1951.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO341354.387e-1443.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Structural maintenance of chromosomes protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
smc41.069e-11937.06structural maintenance of chromosomes 4 [Source:NC... [more]
smc41.069e-11937.06structural maintenance of chromosomes 4 [Source:NC... [more]
smc41.146e-11336.76structural maintenance of chromosomes 4 [Source:NC... [more]
smc1al4.879e-3135.35structural maintenance of chromosomes 1A [Source:N... [more]
smc1b1.683e-1726.36meiosis-specific cohesin subunit SMC1 beta [Source... [more]
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BLAST of Structural maintenance of chromosomes protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000036986.11.754e-11998.55SMESG000036986.1[more]
SMESG000022017.13.437e-2936.53SMESG000022017.1[more]
SMESG000017173.14.025e-1629.88SMESG000017173.1[more]
SMESG000017173.14.302e-1629.88SMESG000017173.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003246 ID=SMED30003246|Name=Structural maintenance of chromosomes protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2958bp
GAAATTTTTCAACATTTATGATGATCAAAAACTTTCAGTTTCCCAAAATT
TGCTAACTTATCTTGATTGCAAATCACATTTCTGCCGTTAAATAAACACT
CCATCGAAGTATAGGAAATTTGCAGAATGTGATGAAAATATTAAACAACA
AAAGCATTTGATCCTTTTTGCAAATGAAGCTCCGAAATCAATATTTATAT
TCCTCATACTCTCATTTCATTACAGTTTTCTTTTTCTCCTTTTTTACCAT
CTAATTTAGCGATTGAAATTAACTCGACAAAATATTATTGGCAACAAAGA
ACATTACGATTCAAACATTAAAGAGATTCCAATAATGGAAAATGAATATA
GAAAAATTACCGAAGAAATTGCAAAATTAAAAGAAATCGAAAAGAAGCTG
AAATCGGAAGTAGATCAATTGAATCATTTATTGAAATCGCGTCAGTCTAA
GGAAACCGAACATAAAGTTCTTAGTTTTTTAATGAATCAGCAATCATCGG
GGAAATTGAAAGGTGTAATTGGACGTCTTGGCAATCTCTGTGCCATTTCT
CCTAAATATGATGTAGCAGTTTCCACCGCATGCACTCGTTTGGATTCGAT
AATCACTGAAGATATAAACGATGCTCAGAAGTGTGTTGAACTGATGAAAC
TACACAAAATTGCTAGATCGACGTTTATTGGATTGAATAAAGTTATCCAA
TGGACAAAGAAAGCCAATGACAAATTCGTAGCTAATATCAATATCCCGAG
AGCATTTGATTTATTAACGATTCCCAATAACGATCACAGGGCGGTTTTGT
ATTTTGCTTTTCGTGATCTGTTATTGGCTAATAACGTTGAAGAAGCACGT
CAAACCAATCAAAGAGCAATGAAATATCGAATTGTCACCTTAAATGTAAC
ATTCGTTTGATATTTATTTCGCAACTGCCTATCGCGTTAAGGGGGAATTA
ATTGAGGTGACCGGCTCCATGACAGGTGGTGGAAGTCGACAGGTCAGAGG
CAAAATATGCACTGATGTAGCACAAATCCAGAAATCGACTCACAGGGACA
GATCGTCCGGTAATTTCGAACCGAAATCCACAGAACAATCCCGTGATAGA
AAAGAACAAGAACTGAATGATGTTATAAATCAAATTAATAATCTAAACGA
AAAAGCCGAGTCGTTGAAAAATCGAATTCAAACAACTAAATTCTCTCAGA
ATAATTTACAAAATTTATTGAAAGATCTCCACCGAGATGAGGAAGATAAT
GAGAAAGAGTTGAATATTTTAGAAGGCAAATTGAAGGCTAATAAGCCCGA
TCCGAAAGCTGTAATATTACTGGAAACCGCCATTCAGAGCCTGAAAAAGA
AATATGAAAAGGATTCTGTCAGAGTTGATTCCCTGAAAGAGGAAGTGAAT
AAAATAATTGAAGAAATCAAATCATTGGGCATTGCAAAATTAGGCACCAT
AAAGTCACGATTGGACGCTATCGATGAACAATATAGAGAGAAAACAGGCA
CACTTATAAAAATAAATATCGCAGTTAAAAAGGCAGAAAAGCTTACGGCA
AAGTTAACAAATGATTTGCAAACTCTGGCATTAGAAAAGACTAAACACGA
AGAAAATTATAAGGAAATGGATGCGACATTAAAGTTGTTGGAAAAGAAAG
CCGGAGATACATTGGCTGAGTATCAAAAAATGAGTGAAGAAGTTCAAGTT
CTCGTGAAACTAAAAGAAGAGCAATCAGTGGAAATTTCAAAAATCAATGA
AAATTTACAGAAATCAAAACATATACATATACAGATTTCTAGGGATTTTG
AGGAAAAGAAAGCAATGGTTGATCAAATTAAGTTGCGTATAAGGCAAATG
AAAGACGACATAAAAAAATTAACATTTTATCCTCTTCCTGAAGGAGTTGA
AGAAGATTCCGAGGATACTTCTTTTATGGATCTTATCGGAGAAAGTGGGG
ACATAAATATCTTCAGCTCACAAAAAGACTCCCACTCTGGAACGACATTA
AAAGTGTACTCCAATGAAGAGTTATTGAAGTTTAAAAACCACCAAATCAC
CTATCAGGATATGGAAGATAAATTGAATAAGCAAAAACCAAATTTGGCTG
CTATTGAAGAATATCGAATGAAAGAAGAACTATATATGTTAAGGGCAGCC
GAATTGACAGAAGTAACCCAGTTTAGAGATCAACAAAGAGATCAATTAGA
GAAAATGAAACGACAAAGACACCAGGAGTTTACTGCGGGATTTAACCTAA
TAACAACGAAACTCAAAGAAATGTACCAAATGATTACAATGGGAGGAGAT
GCAGAATTGGAACTCGTCGATTCATTGGATCCGTTTTCTGAAGGAATTTT
ATTCAGTGTTCGTCCACCGAAAAAGTCCTGGAAAAATATCAGTAATCTTT
CCGGTGGAGAAAAAACCCTTTCATCATTGGCTCTTGTGTTTGCGTTGCAT
CATTTCAAGCCGACTCCGTTCTATGTGATGGATGAAATCGACGCAGCCTT
GGATTTTAAGAACGTTTCAATTGTAGCTAACTATATCAAAGACCGAACGA
AAAATGCTCAGTTCATAATCATTTCCCTCCGAAATAACATGTACGAATTA
GCCGACTGTTTGATCGGTATTAATAAGCCGTTTAATTTCACGAAAACCTG
CTTGCTTAATTTGAAAGCAGTCGATTGTTCTTTGCAGCATGTTTGTAACA
CTGAGAAACTACCACATCCGATGATTTTAAATCCAGCATCGCAAGCAGCA
TCTCAAGAAAAAAGTCCCATTGATAATGATGTGCAAATCGTAATTGATTA
ATAAATAAAGTGTTTATATTTGTAAATGTTTTAATAATTTGTAATATATT
TGTGTTTATTTATATTTTTATTGGTTTTTTACTGAATTGCATTTTTATAT
TTGTTAAAATGTATTTTGTTTGTATATGTTAAATTTTAATGAAATTTAAT
TTAATGAT
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protein sequence of SMED30003246-orf-1

>SMED30003246-orf-1 ID=SMED30003246-orf-1|Name=SMED30003246-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=192bp
MENEYRKITEEIAKLKEIEKKLKSEVDQLNHLLKSRQSKETEHKVLSFLM
NQQSSGKLKGVIGRLGNLCAISPKYDVAVSTACTRLDSIITEDINDAQKC
VELMKLHKIARSTFIGLNKVIQWTKKANDKFVANINIPRAFDLLTIPNND
HRAVLYFAFRDLLLANNVEEARQTNQRAMKYRIVTLNVTFV*
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protein sequence of SMED30003246-orf-2

>SMED30003246-orf-2 ID=SMED30003246-orf-2|Name=SMED30003246-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=611bp
MTGGGSRQVRGKICTDVAQIQKSTHRDRSSGNFEPKSTEQSRDRKEQELN
DVINQINNLNEKAESLKNRIQTTKFSQNNLQNLLKDLHRDEEDNEKELNI
LEGKLKANKPDPKAVILLETAIQSLKKKYEKDSVRVDSLKEEVNKIIEEI
KSLGIAKLGTIKSRLDAIDEQYREKTGTLIKINIAVKKAEKLTAKLTNDL
QTLALEKTKHEENYKEMDATLKLLEKKAGDTLAEYQKMSEEVQVLVKLKE
EQSVEISKINENLQKSKHIHIQISRDFEEKKAMVDQIKLRIRQMKDDIKK
LTFYPLPEGVEEDSEDTSFMDLIGESGDINIFSSQKDSHSGTTLKVYSNE
ELLKFKNHQITYQDMEDKLNKQKPNLAAIEEYRMKEELYMLRAAELTEVT
QFRDQQRDQLEKMKRQRHQEFTAGFNLITTKLKEMYQMITMGGDAELELV
DSLDPFSEGILFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHFKPTP
FYVMDEIDAALDFKNVSIVANYIKDRTKNAQFIIISLRNNMYELADCLIG
INKPFNFTKTCLLNLKAVDCSLQHVCNTEKLPHPMILNPASQAASQEKSP
IDNDVQIVID*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR010935SMC_hinge
IPR003395RecF/RecN/SMC_N
IPR027417P-loop_NTPase
IPR011528NERD
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0005515protein binding
Vocabulary: biological process
TermDefinition
GO:0051276chromosome organization
Vocabulary: cellular component
TermDefinition
GO:0005694chromosome
GO:0005634nucleus