WD repeat-containing protein 3
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30003242 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of WD repeat-containing protein 3 vs. Ensembl Human
Match: WDR3 (WD repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:12755]) HSP 1 Score: 157.918 bits (398), Expect = 2.299e-77 Identity = 123/437 (28.15%), Postives = 208/437 (47.60%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLT-IKTMNTERNADKLMEAIDIY--------DKIQIDPTA------PIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA 2811
DL ++L+ + H ++ ++ L+ DQR ++ GADK + W+ E + +S LS V Q + V+ +P+ KL + +D V+ + DT + L LYGH +PV + + +D + + TGS+D++V+ W L GDC K H + V ++++P + F+ K I Q D I L GH Q + L+V G +VS S D+S+R W +++ L+ E E+ E + YE+ ++ + G + G + T KT+ T + A+++MEAI++Y + I A P +P++ G +VL I +LE L LP +Y +L + + + G V L RC FL ++HF + + LVP I K+ + + + DVIGFN+A
Sbjct: 482 DLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFEL----VKDENSTQKRLS-VKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYV-DTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDY----------VVSSSHDKSLRLWERTREPLILEEEREMEREAEYEESVAKEDQPAVPGETQ--GDSYFTGKKTIETVKAAERIMEAIELYREETAKMKEHKAICKAAGKEVPLPSNPILMAYGSISPSAYVLEIFKGIKSSELEESLLVLPFSYVPDILKLFNEFIQLGSDVELICRCLFFLLRIHFGQITSNQMLVPVIEKLRETTISKVSQVRDVIGFNMA 900 HSP 2 Score: 153.68 bits (387), Expect = 2.299e-77 Identity = 138/530 (26.04%), Postives = 244/530 (46.04%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNT--HQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKKIDSDPFESTVQ-------------EQYSNAIQATPVP----------GEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXX---------XXXXXXXDP-ANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++ +FGVIG + NI F+ R G G V E V IW+L E + L G + +V+ L + GLH+++GYE G I ++ + + E V+ HK +I+ + ++ +L GSKDT I + DV +E G ++L+GHK IT+ ++ +K++L++S +D +K+W L + CFKT+ E+W L+TG+S++ LR+W + + + DP E + E A + P G + RE RVV + +D+TG L + + LEL+ +L++ E++K++ KK+K + + DP NV ++ D ++ + I+ + K + P + K L + NN + ++++ S + T + I+ GHR+ + +SDN+A+ + + +WN+S+ + T T +Y A + +PGDR +IG K G
Sbjct: 1 MGLTKQYLRYVASAVFGVIGSQKGNIVFVTLR-GEKGRYVAVPACEHVFIWDLRKGEKILILQG-LKQEVTCLCPSPD---GLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIEDPEEPDPKKIKGSSPGIQDTLEAEDGAFETDEAPEDRILSCRKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLELFCILSKKEIQKKMDKKMKKARKKAKLHSSKGEEEDPEVNVEMSLQDEIQRVTNIKTSAKIKSFDLIHSPHGELKAVFL-----LQNNLVELYSLNPS----------------LPTPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTM--TCEY--------------------------ALCSFFVPGDRQVVIGTKTG 476
BLAST of WD repeat-containing protein 3 vs. Ensembl Human
Match: RACK1 (receptor for activated C kinase 1 [Source:HGNC Symbol;Acc:HGNC:4399]) HSP 1 Score: 63.929 bits (154), Expect = 1.681e-10 Identity = 63/234 (26.92%), Postives = 106/234 (45.30%), Query Frame = 1
Query: 1579 VKRHTESISALVLT-QDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTY-LTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIF---RGHTEPVTDVKYIPGRS--MAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTE-ADGDELENAELVSVSTDRSIRFW 2256
+K H ++ + T Q +LSA DK ++MW + T I Q + +S V ++ DG+ + G D +R + LTT T+ R GH+ V S++ D+ Q+++GS DK+++ WN G CK H+E V+ V++ P S + SC L+ +L N GH +++++V G+ A G + L + TD +R W
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIP-----------QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR--RFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGK----TLFAGYTDNLVRVW 226
BLAST of WD repeat-containing protein 3 vs. Ensembl Human
Match: TAF5 (TATA-box binding protein associated factor 5 [Source:HGNC Symbol;Acc:HGNC:11539]) HSP 1 Score: 66.2402 bits (160), Expect = 2.364e-10 Identity = 56/256 (21.88%), Postives = 107/256 (41.80%), Query Frame = 1
Query: 1546 VDLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEEND 2310
+D S L+ + H+ + + D+ +LS+ D + +W+++ + C + + +P G F+ G D R + TD + + GH V +S+ + TGS+D++VR W++ +G+C +IF GH P+ + + P + G ++ D+ + + L+GH +V SL DG+ L S S D ++R W ++ E +E +D
Sbjct: 528 MDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ----------------TFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLW-ATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF-----SRDGE-----ILASGSMDNTVRLW-----DAIKAFEDLETDD 751 HSP 2 Score: 56.6102 bits (135), Expect = 2.012e-7 Identity = 42/130 (32.31%), Postives = 57/130 (43.85%), Query Frame = 1
Query: 1762 FKNA---ISSVAVTPDGKLFIIGFMDSKVRTYLTT---------------------DTSRRVLD---------LYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKI-FRGHTEPVTDVKYIP 2049
F NA +++V VT D L GF DS VR + T D R++D LYGHS PV S D + LL+ S D +VR W+L C + ++GH PV D ++ P
Sbjct: 466 FLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 595
BLAST of WD repeat-containing protein 3 vs. Ensembl Human
Match: WDR48 (WD repeat domain 48 [Source:HGNC Symbol;Acc:HGNC:30914]) HSP 1 Score: 64.6994 bits (156), Expect = 6.427e-10 Identity = 47/179 (26.26%), Postives = 91/179 (50.84%), Query Frame = 1
Query: 1579 VKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHN 2112
++ H + + AL +D+ V SAG D+ + +W++ + TA+T +++ + SL K++I S+A+ G + + G + +R + T +++ L GH+ V ++ + D +Q L+GSSD ++R W+L C +R H E V ++ + +S + I DL N
Sbjct: 113 LRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN-TLTALTASNNTVTTSSLSGN------KDSIYSLAMNQLGTIIVSGSTEKVLRVW-DPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRN 283
BLAST of WD repeat-containing protein 3 vs. Ensembl Human
Match: RACK1 (receptor for activated C kinase 1 [Source:HGNC Symbol;Acc:HGNC:4399]) HSP 1 Score: 63.1586 bits (152), Expect = 7.132e-10 Identity = 69/276 (25.00%), Postives = 116/276 (42.03%), Query Frame = 1
Query: 1579 VKRHTESISALVLT-QDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTY-LTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIF---RGHTEPVTDVKYIPGRS--MAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGT-----------------------EADGDELENAELVS-------VSTDRSIRFWYESQDILVREVEQ 2295
+K H ++ + T Q +LSA DK ++MW + T I Q + +S V ++ DG+ + G D +R + LTT T+ R GH+ V S++ D+ Q+++GS DK+++ WN G CK H+E V+ V++ P S + SC L+ +L N GH +++++V G+ DG ++ NA S +T SI+ W I+V E++Q
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIP-----------QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR--RFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQ 272
BLAST of WD repeat-containing protein 3 vs. Ensembl Celegans
Match: F13H8.2 (pep chromosome:WBcel235:II:6270370:6274005:1 gene:WBGene00017435.1 transcript:F13H8.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F13H8.2) HSP 1 Score: 122.865 bits (307), Expect = 3.729e-28 Identity = 110/429 (25.64%), Postives = 195/429 (45.45%), Query Frame = 1
Query: 1582 KRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAF-SCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIY--DKIQI--DPTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIAHFKRHMKLMGPEL 2850
K HT +I + + D ++A ADK + W+ + + +S+ Q+ E A+++ + + DGK ++ +++ Y +T + + LYGHS+PVT + + S +TGS DKSV+ W L GDC K F H + VT V + PG F S K G I Q D + L H + L+ G+ + S S D+SIR W ++ +IL+ E + E + YEK ++ E V+ G D V + KT ++ +A+ +++A+DI +K+Q DP PL+ F++ ++ DL+ L +P++Y +L ++ + + L +L ++H + VP +M +++ +V G N+A ++L+ EL
Sbjct: 490 KAHTGAIWTIQNSPDNEGFITASADKTVRFWSF------VLVTEGSRKRISIKEQKVLELPDEALAA-SFSADGKFLVVALLNNTCSVYFV-NTLKFFVSLYGHSLPVTCVDIAPSSKLCVTGSVDKSVKVWGLDFGDCHKSFHAHDDAVTSVLFCPGEEQLFWSAGKDGKIKQWDAVKFIMVQVLDRHTLDIRCLAQFTNGS----------VMFSASHDKSIRCWEKTDEILIVEEREEVEREEEYEK-KLIEEEDVVAGENADNEAGVASSKTSSSVVSAENIIQAVDIARNEKVQRQEDPGHEPHPLIGAYNSKSLDHFIVDVVAKCRASDLDRTLLLVPLSYVADILLAISSCTQQQYKAELCTHVAVYLTRIHLSHITASSDYVPIFEQMKSKMSEGVEKLRNVTGINLA----ALRLLATEL 895 HSP 2 Score: 80.8777 bits (198), Expect = 2.837e-15 Identity = 73/314 (23.25%), Postives = 131/314 (41.72%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNTHQ---LICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTTSI-EIWDFFYCDTRNLLVTGSSETTLRLWRLDFKK------------------IDSDPFESTVQEQYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAE 928
+G+ K+YLK+ H G +G N + + G V E + +N+ T E V ++ + +S ++IGY G + +++ + + + G KD I + D+ ERG F+L GHK +T++ ++ +IS+S+D IKFW ++ + CF T+ S EI+ +LV ++E L ++ L++K + D E V +N T + G V R+S R +++ +LV +K ++YRV +E E
Sbjct: 1 MGLTKDYLKYEHAGSCGCVGSANGQLVAID------GQTVAVSANEYLNFYNMRTAEKV----NEIIESTKPISCVRQCENKPLLAIGYADGSVKLFNQENEDSEPIMFSGHKKAVNCIEFSSDGLLFATGGKDGVIVLWDILAERGMFRLHGHKESVTQMKFVRGDRFIISTSKDSLIKFWSIASQSCFYTVMDSRNEIYSMSLHRDETVLVAATAELELLVFELNWKNGAIFEQEVKSEEPSAKKATNDDEKEDDVLANMANRYITTKLRGRVIRQSKGRALQLVATHDDRFLVCVGADKVADVYRVFSETE 304
BLAST of WD repeat-containing protein 3 vs. Ensembl Celegans
Match: wdr-5.2 (WD repeat-containing protein wdr-5.2 [Source:UniProtKB/Swiss-Prot;Acc:Q93847]) HSP 1 Score: 58.9214 bits (141), Expect = 1.096e-8 Identity = 59/270 (21.85%), Postives = 99/270 (36.67%), Query Frame = 1
Query: 1567 VLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHG-NSLSLV------------------------CQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC--KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQ 2295
V + H +SIS + + D R + S AD + +W +++ + H G N S C +T + N + P G L G D +R + + + + GH PV+S+ D + L +GS D VR W+ G C + P+T VK+ P + + + + D + + GH +S VA G + +VS S D + W ++ RE+ Q
Sbjct: 99 VAEIPNAHKKSISGIKFSPDGRYMGSGSADCSIKIWRMDFVYEKTLMGHRLGINEFSWSSDSKLIVSCSDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTLIASGSFDETIRIWCARN-GNTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHVKFSPNGKYILASNLNNTLKLWDYQKLRVLKEYTGH---ENSKYCVAANFSVTGGKW----IVSGSEDHKVYIW----NLQTREILQ 356
BLAST of WD repeat-containing protein 3 vs. Ensembl Celegans
Match: wdr-5.1 (WD repeat-containing protein wdr-5.1 [Source:UniProtKB/Swiss-Prot;Acc:Q17963]) HSP 1 Score: 58.5362 bits (140), Expect = 1.132e-8 Identity = 62/280 (22.14%), Postives = 120/280 (42.86%), Query Frame = 1
Query: 1588 HTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSL------SVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRC-YEKEEMARERIVIVGAPRDTGINVLTIKT 2403
HT+SIS+ + + + ++ ADK + +WN+++ ++C+ T K ++ +A + D + ++ D K TSR L GH+ V + SS +++GS D+SVR W++ G C K H++PV+ V + S+ S GL+ D N GQ + +L V + +G + + L D +++ W S+ +++ E + C + + + +I G+ D I + ++T
Sbjct: 86 HTKSISSAKFSPCGKYLGTSSADKTVKIWNMDH----------------MICERTLTGHKLGVNDIAWSSDSRC-VVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTAN----------GQCIKTLVDDENPPVAFVKFSPNGKYILASNL-----DSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGGKWIISGS-EDCKIYIWNLQT 332 HSP 2 Score: 55.4546 bits (132), Expect = 1.103e-7 Identity = 59/241 (24.48%), Postives = 93/241 (38.59%), Query Frame = 1
Query: 1588 HTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC--KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEE 2304
H ++ + + D RCV+SA DK L ++ I S T+ H N + C P+ L + G D VR + T + L HS PV+++S D S + +GS D VR W+ +G C + PV VK+ P + + + D + + GH S + A + G ++S S D I W ++ RE+ Q E
Sbjct: 128 HKLGVNDIAWSSDSRCVVSASDDKTLKIFEIVTSRMTKTL-KGHNNYV-FCCNFNPQ--------------SSLVVSGSFDESVRIW-DVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHEN--SKYCIFANFSVTGG-----KWIISGSEDCKIYIW----NLQTREIVQCLE 340
BLAST of WD repeat-containing protein 3 vs. Ensembl Celegans
Match: wdr-5.1 (WD repeat-containing protein wdr-5.1 [Source:UniProtKB/Swiss-Prot;Acc:Q17963]) HSP 1 Score: 58.5362 bits (140), Expect = 1.132e-8 Identity = 62/280 (22.14%), Postives = 120/280 (42.86%), Query Frame = 1
Query: 1588 HTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSL------SVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRC-YEKEEMARERIVIVGAPRDTGINVLTIKT 2403
HT+SIS+ + + + ++ ADK + +WN+++ ++C+ T K ++ +A + D + ++ D K TSR L GH+ V + SS +++GS D+SVR W++ G C K H++PV+ V + S+ S GL+ D N GQ + +L V + +G + + L D +++ W S+ +++ E + C + + + +I G+ D I + ++T
Sbjct: 86 HTKSISSAKFSPCGKYLGTSSADKTVKIWNMDH----------------MICERTLTGHKLGVNDIAWSSDSRC-VVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTAN----------GQCIKTLVDDENPPVAFVKFSPNGKYILASNL-----DSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGGKWIISGS-EDCKIYIWNLQT 332 HSP 2 Score: 55.4546 bits (132), Expect = 1.103e-7 Identity = 59/241 (24.48%), Postives = 93/241 (38.59%), Query Frame = 1
Query: 1588 HTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC--KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEE 2304
H ++ + + D RCV+SA DK L ++ I S T+ H N + C P+ L + G D VR + T + L HS PV+++S D S + +GS D VR W+ +G C + PV VK+ P + + + D + + GH S + A + G ++S S D I W ++ RE+ Q E
Sbjct: 128 HKLGVNDIAWSSDSRCVVSASDDKTLKIFEIVTSRMTKTL-KGHNNYV-FCCNFNPQ--------------SSLVVSGSFDESVRIW-DVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHEN--SKYCIFANFSVTGG-----KWIISGSEDCKIYIW----NLQTREIVQCLE 340
BLAST of WD repeat-containing protein 3 vs. Ensembl Celegans
Match: T02H6.1 (pep chromosome:WBcel235:II:709381:723699:1 gene:WBGene00020171.1 transcript:T02H6.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T02H6.1) HSP 1 Score: 56.225 bits (134), Expect = 9.329e-8 Identity = 56/247 (22.67%), Postives = 105/247 (42.51%), Query Frame = 1
Query: 1582 KRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPH-GDCKIFRGHTEPVTDVKYIPGRSMAF--SCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW--YESQDILVREVEQMEEN 2307
K H S + + D + V+S G + ++ +N+ I + + V +E I +VAV+PD K G D V+ + D+ + DL GH P+ S++ + ++ L + S D+SV+ W++ G GH + V + + + +A D+S + +++ + L Q+ SL VAM + + S D SI W ++ + + VR+ +N
Sbjct: 137 KPHRLSPLCVAFSPDAKYVISCGKESSIVKFNVGTRKVVGIIKRT--KKRAGVPEEPTNAHYGVIFTVAVSPDQKFIASGGFDQVVKIW-NFDSLEHIKDLSGHRGPIFSLTFQLKTNNLYSASQDRSVKMWDIDQLGLVDTMYGHQDGVQQIGVLSKQRVATVGGRDRSARLWKVEDESQLMFSGL----QNCVSLDCVAM--------INEEHFATGSADGSIALWSFWKKRALHVRKQAHGTQN 368
BLAST of WD repeat-containing protein 3 vs. Ensembl Fly
Match: CG8064 (gene:FBgn0038597 transcript:FBtr0083574) HSP 1 Score: 148.673 bits (374), Expect = 7.204e-61 Identity = 112/427 (26.23%), Postives = 208/427 (48.71%), Query Frame = 1
Query: 1546 VDLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC--KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQD-ILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIYDKIQIDP--TAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPV-TYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNI 2808
VD+ +++ + H + ++ + DQ+ ++ D + +W E A + LSL+ + T + + + +AV+PD K +G +D+ V+ + DT + L LYGH +PV + + YDS+ ++TGS+D++V+ W L GDC IF H + V V++IP M F+C K G + Q D N +I+ L GH LSV G LV+ +DR++R + + + I++++V++ E E+ + V P G+ + + KT+ +E++A+ ++E ++I + +++ + PLM + F++ T+ I DLE L LP T ++L + + Q+ L R FL K+H + + P + K+ K + + DV+G+N+
Sbjct: 469 VDVAAADIVEEIPAHEGELWSIAILPDQKGCVTGSGDTTVKIWTFELIDAGEGAAQT--KVLSLLHKNTLK-LEETVLCLAVSPDMKYLAVGLLDATVKVFFL-DTFKFYLSLYGHKLPVICLDISYDSNLIVTGSADRNVKVWGLNFGDCHRSIF-AHDDSVMSVQFIPRTHMFFTCGKDGKVKQWDGDNFEKILTLPGHIGEAYCLSVSPNGR----------YLVTCGSDRTLRMFERTDETIVLKDVQEEEREQMENEQLATGEDNTV----PLLPGLKMPSRKTVGSEQSAESILECLEISKQFELEAEEKPELHPLMQALQVKNPEDFLVSTLMRIRASDLEEALLLLPFSTVCEVLERLPTLLTQRPDQLELLCRVTIFLFKVHMKPISAAKNMKPLLVKLLSMLKRDVGQLRDVLGWNL 876 HSP 2 Score: 107.071 bits (266), Expect = 7.204e-61 Identity = 136/520 (26.15%), Postives = 242/520 (46.54%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSY-LSYTHSDIFGLHISIGYESGYISVYDVST---YELXXXXXXXXXXXXYILHNTH--QLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISK---KDVLISSSQDGEIKFWFLSLKRCFKTLTTS-IEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKKID---SDPFESTVQEQYSNAIQATPVP------GEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRV-------AIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL + F +I +N++F D G AE+VI+W+L + TL + + S +S H LHI++GY G + ++D+S+ Y+ + + +HK+++S + ++ +L+ G DT + ++DV ++ G +L GH + IT H++ + + +++S S+D +IKFW L + CFKT+ + E+W + NL+V G+ E+ + ++RL +K D ++ ES V E S + T P G + R R V + D + + + +E + + T E+KKRL K+LKK K D SD KL L KR+ I S+ + L +LVS+ NN++ ++++ S A D + +R S+++ GH++ + ++D+LAI S AG ++ + D D + + T+ L S +PGDR+ L+G K+G
Sbjct: 1 MGLTKQYLAYRAIDSFNIITSGRANVNF-AVVDKTEGRYVAAPAAENVIVWDLRMGDRKLTLRREKFEVTSLRVSPDH-----LHIAVGYADGMVQIFDLSSDRYYDPICTLALHKNAVSILRYDLQGMRLVSGGLDTELVVVDVVEQAGRARLSGHNAAITDAHFLQRLVDESIVVSCSKDTQIKFWNLETQFCFKTIVDNRTEVWALAFIG--NLMVAGAGESGMNVYRL--RKHDGAITETLESAV-EGLSIDDEDTISPISVSNCGTIQRAGKGRTVNLVTDPSERVISCHGTNDLIENFYICTPDEVKKRLAKRLKKEKKVAED------EGSDEAKLSTEQSLSDEIKRLESIRAKQKIKSIDVVLGQNQELRVLVSLANNSLCLYSLEAS----------IKTRKATDPSAKLLR-SLTRLGHQSEVRSVCFSNDSLAI------------------GSGAGESFKF-WDRDAMQCLRTVPTDYILCSK---------FVPGDRYVLLGMKSG 464
BLAST of WD repeat-containing protein 3 vs. Ensembl Fly
Match: CG9062 (gene:FBgn0033607 transcript:FBtr0332422) HSP 1 Score: 67.781 bits (164), Expect = 4.089e-11 Identity = 41/140 (29.29%), Postives = 77/140 (55.00%), Query Frame = 1
Query: 1579 VKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC 1998
++ H + + AL +D+ V SAG DK + +W++ + TA+T +++ + SL K++I S+A+ P G + + G ++ +R + RR + L GH+ V + V D +Q+++GSSD +++ WNL C
Sbjct: 111 LRTHRDYVQALAYAKDREQVASAGLDKAIFLWDVN-TLTALTASNNTVTTSSLTGS------KDSIYSLAMNPSGTVIVSGSTENILRIWDPRTCMRR-MKLRGHTENVRCLVVSPDGNQVVSGSSDGTIKVWNLGQQRC 242
BLAST of WD repeat-containing protein 3 vs. Ensembl Fly
Match: CG9062 (gene:FBgn0033607 transcript:FBtr0088181) HSP 1 Score: 67.3958 bits (163), Expect = 4.363e-11 Identity = 41/140 (29.29%), Postives = 77/140 (55.00%), Query Frame = 1
Query: 1579 VKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC 1998
++ H + + AL +D+ V SAG DK + +W++ + TA+T +++ + SL K++I S+A+ P G + + G ++ +R + RR + L GH+ V + V D +Q+++GSSD +++ WNL C
Sbjct: 111 LRTHRDYVQALAYAKDREQVASAGLDKAIFLWDVN-TLTALTASNNTVTTSSLTGS------KDSIYSLAMNPSGTVIVSGSTENILRIWDPRTCMRR-MKLRGHTENVRCLVVSPDGNQVVSGSSDGTIKVWNLGQQRC 242
BLAST of WD repeat-containing protein 3 vs. Ensembl Fly
Match: slmb (gene:FBgn0283468 transcript:FBtr0084032) HSP 1 Score: 57.7658 bits (138), Expect = 4.105e-8 Identity = 56/205 (27.32%), Postives = 97/205 (47.32%), Query Frame = 1
Query: 1798 DGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGD-CKIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLR---GHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIK 2400
DGK+ + G D+ ++ + TD + V L GH+ V + ++YD +++GSSD +VR W++ G+ H E V +++ G M +C K I D+ + SEI R GH +V+ + + + +VS S DR+I+ W S VR + + C + R+R+V+ G+ D I + I+
Sbjct: 220 DGKI-VSGLRDNTIKIWDRTDL-QCVKTLMGHTGSV--LCLQYDDKVIISGSSDSTVRVWDVNTGEMVNTLIHHCEAVLHLRFNNG--MMVTCSKDRSIAVWDMTSPSEITLRRVLVGHRAAVNVV------------DFDEKYIVSASGDRTIKVWSTSSCEFVRTLNGHKRGIACLQ----YRDRLVVSGSS-DNSIRLWDIE 401
BLAST of WD repeat-containing protein 3 vs. Ensembl Fly
Match: slmb (gene:FBgn0283468 transcript:FBtr0333931) HSP 1 Score: 57.7658 bits (138), Expect = 4.105e-8 Identity = 56/205 (27.32%), Postives = 97/205 (47.32%), Query Frame = 1
Query: 1798 DGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGD-CKIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLR---GHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIK 2400
DGK+ + G D+ ++ + TD + V L GH+ V + ++YD +++GSSD +VR W++ G+ H E V +++ G M +C K I D+ + SEI R GH +V+ + + + +VS S DR+I+ W S VR + + C + R+R+V+ G+ D I + I+
Sbjct: 220 DGKI-VSGLRDNTIKIWDRTDL-QCVKTLMGHTGSV--LCLQYDDKVIISGSSDSTVRVWDVNTGEMVNTLIHHCEAVLHLRFNNG--MMVTCSKDRSIAVWDMTSPSEITLRRVLVGHRAAVNVV------------DFDEKYIVSASGDRTIKVWSTSSCEFVRTLNGHKRGIACLQ----YRDRLVVSGSS-DNSIRLWDIE 401
BLAST of WD repeat-containing protein 3 vs. Ensembl Zebrafish
Match: wdr3 (WD repeat domain 3 [Source:ZFIN;Acc:ZDB-GENE-030131-9830]) HSP 1 Score: 161.384 bits (407), Expect = 6.850e-79 Identity = 139/523 (26.58%), Postives = 251/523 (47.99%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNT--HQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRL-DFKKID--SDPFESTVQ--------------EQYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXX---------XXXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++ +FGVIG + +NI+F+ R G G VG E V IW++ E V L GK + V+YL + G+HI++GYE G + ++ + E VS HK ++S I ++ +L+ GS+DT + + DV +E G ++L+GHK IT++ ++ K++LI+SS+D +K+W L + CFKT+ E+W + N L+TGS+++ LR W + D +++ +P E V+ E+ I + G + RE+ RVV + D L + L+ LE++ VL+E E+++++ + K ++ + ++P V D + L I + + + VP +++++ + NNT+ +T+ + T + T R ++ GHR+ + +SDN+AI + S +WN+S+ + T G + A ++ +PGDR ++G K+G
Sbjct: 1 MGLTKQYLRYVASAVFGVIGSQKANIAFVTLRGGEKGRYVAVGACEHVFIWDVRKAEKVLILEGKKHE-VTYLCPSPD---GVHIAVGYEDGGVRIFSLLNGESNVSFSGHKSAVSVIKYDALGARLVTGSRDTDVIVWDVINECGLYRLKGHKDAITQVLFLESKNLLITSSKDSFVKWWDLDTQHCFKTMVGHRSEVWGMVLLNQENRLLTGSADSELRAWDIQDIEEVKELGEPQEKKVRTLLEDEEEDEEGPDEEPEERILSCKKAGSILREARDRVVSLVTDAKAKVLACHGLDATLEVFTVLSEEEIQRKMDRKLKKAKKKAKSQEGGEEASEPV-VERKLKDEIMKLANIRASSKIRSMDCLLVP-----NGEMKVVLLLQNNTVETYTLKTTEKN--------------PTGNKTSRLTLG--GHRSDVRTVAFSSDNIAILSASGDTVKVWNRSTLQVIRTMGCEY----------------------------ALCSIFVPGDRQIILGTKSG 469 HSP 2 Score: 154.451 bits (389), Expect = 6.850e-79 Identity = 117/437 (26.77%), Postives = 205/437 (46.91%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIYDKIQID---------------PTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA 2811
DL S+L+ H ++ ++ L+ DQR +++ GADK + W+ E I S N V + V +PD +L + +D V+ + T DT + L LYGH +PV + + +DS+ + TGS+D++V+ W L GDC + H + V ++++P + F+ K I Q D I L GH + V L++ +GD +VS S D+S+R W +++ ++ E E+ E + +E+ + V+ G + KT+ T + A+++MEAI++Y + + P ++P++ G R+VL + + +LE+ L LP Y LL + V +G +V L RC FL ++HF + + L+ I ++ ++ DV+GFN A
Sbjct: 475 DLASGSLLETTDAHEGALWSMCLSPDQRGIVTGGADKTVKFWDFEL----IKDEDSMINKRLTVKHTRTLQLDEDVLCVRFSPDQRLLAVSLLDCTVKIFYT-DTLKFFLSLYGHKLPVLCLDISHDSALIATGSADRNVKIWGLDFGDCHRSMFAHDDSVMFLQFVPKTHLFFTAGKDKKIKQWDADKFEHIQTLEGHHREVWCLAI-----SPNGD-----HIVSSSHDKSLRLWERTREPIILEEEKEMEREAEFEESLAKGDDPVVPGETKGEA-EPAGRKTVETVKAAERIMEAIELYREESKNLEEHKAACEAAGKKLPPLKMNPILMAFGNISPSRYVLEVMKKVRSSELEVSLLVLPFPYVPDLLKLFNAYVKEGLEVELVCRCLFFLLRVHFGQITSNQMLLSVIDELRANTISKVREIRDVLGFNSA 895 HSP 3 Score: 54.6842 bits (130), Expect = 6.580e-7 Identity = 47/187 (25.13%), Postives = 88/187 (47.06%), Query Frame = 1
Query: 1756 EPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDS--SQLLTGSSDKSVRSWNLPHGDCKIFR--GHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEE 2304
E K+ ++ + +PDG +G+ D VR + + V GH V+ I KYD+ ++L+TGS D V W++ + +C ++R GH + +T V ++ +++ + K + DL + GH V + ++ + L++ S D +R W + QDI EV+++ E
Sbjct: 63 EGKKHEVTYLCPSPDGVHIAVGYEDGGVRIFSLLNGESNV-SFSGHKSAVSVI--KYDALGARLVTGSRDTDVIVWDVIN-ECGLYRLKGHKDAITQVLFLESKNLLITSSKDSFVKWWDLDTQHCFKTMVGHRSEVWGMVLLN----------QENRLLTGSADSELRAW-DIQDI--EEVKELGE 232
BLAST of WD repeat-containing protein 3 vs. Ensembl Zebrafish
Match: taf5 (TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor [Source:ZFIN;Acc:ZDB-GENE-051120-180]) HSP 1 Score: 70.0922 bits (170), Expect = 1.114e-11 Identity = 55/242 (22.73%), Postives = 107/242 (44.21%), Query Frame = 1
Query: 1588 HTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEEND 2310
H+ + + + D+ +LS+ D + +W+++ + C + + +P G F+ G D R + TD + + GH VT +S+ + TGSSD++VR W++ +G+C +IF GH P+ + + P S G ++ D+ + I L+GH + ++ A+ DG+ + S S D ++R W D++ R ++ +E +D
Sbjct: 498 HSGPVYGVSFSPDRNYLLSSSEDGTIRLWSLQ----------------TFTCLVGYKGHNYPVWDTQFSPFGYYFVSGGHDRVARLW-ATDHYQPLRIFAGHLADVTCTRFHPNSNYVATGSSDRTVRLWDVLNGNCVRIFTGHKGPIHSLAFSPNGKFLASGSTDGRVLLWDIGHGLMIAELKGH-----TGTIYALKFSRDGE-----IIASGSIDNTVRLW----DVM-RAIDDVETDD 707 HSP 2 Score: 53.9138 bits (128), Expect = 8.972e-7 Identity = 39/139 (28.06%), Postives = 59/139 (42.45%), Query Frame = 1
Query: 1726 SLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTT---------------------DTSRRVLD---------LYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKI-FRGHTEPVTDVKYIP 2049
+L +C T +++V T D L GF DS VR + T D R++D L+GHS PV +S D + LL+ S D ++R W+L C + ++GH PV D ++ P
Sbjct: 413 TLPSICFYTFLNAYQGLTAVDFTDDSSLIAGGFADSTVRVWSVTPKKLRKVKSAADLNLIDKESDDVLERIMDEKTSSESKILHGHSGPVYGVSFSPDRNYLLSSSEDGTIRLWSLQTFTCLVGYKGHNYPVWDTQFSP 551
BLAST of WD repeat-containing protein 3 vs. Ensembl Zebrafish
Match: wdr48b (WD repeat domain 48b [Source:NCBI gene;Acc:334682]) HSP 1 Score: 67.0106 bits (162), Expect = 8.898e-11 Identity = 49/182 (26.92%), Postives = 92/182 (50.55%), Query Frame = 1
Query: 1570 LQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHN 2112
+ ++ H + + AL +D+ V SAG D+ + +W++ + TA+T +++ + SL K++I S+A+ G + I G + +R + T +++ L GH+ V S+ + D +Q L+GSSD ++R W+L C +R H E V ++ + +S + I DL N
Sbjct: 110 MSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN-TLTALTASNNTVTTSSLSGN------KDSIYSLAMNQTGTVIISGSTEKVLRVW-DPRTCAKLMKLKGHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNEAFTHIYSGGRDRKIYCTDLRN 283
BLAST of WD repeat-containing protein 3 vs. Ensembl Zebrafish
Match: wdr48a (WD repeat domain 48a [Source:ZFIN;Acc:ZDB-GENE-061110-55]) HSP 1 Score: 65.0846 bits (157), Expect = 2.529e-10 Identity = 48/182 (26.37%), Postives = 92/182 (50.55%), Query Frame = 1
Query: 1570 LQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHN 2112
+ ++ H + + AL +D+ V SAG D+ + +W++ + TA+T +++ + SL K++I S+A+ G + + G + +R + T +++ L GH+ V S+ + D +Q L+GSSD ++R W+L C +R H E V ++ + +S + I DL N
Sbjct: 109 MSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN-TLTALTASNNTVTTSSLSGN------KDSIYSLAMNQMGTVIVSGSTEKVLRVW-DPRTCAKLMKLKGHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNEAFTHVYSGGRDRKIYCTDLRN 282
BLAST of WD repeat-containing protein 3 vs. Ensembl Zebrafish
Match: wdr48a (WD repeat domain 48a [Source:ZFIN;Acc:ZDB-GENE-061110-55]) HSP 1 Score: 64.6994 bits (156), Expect = 3.547e-10 Identity = 48/182 (26.37%), Postives = 92/182 (50.55%), Query Frame = 1
Query: 1570 LQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHN 2112
+ ++ H + + AL +D+ V SAG D+ + +W++ + TA+T +++ + SL K++I S+A+ G + + G + +R + T +++ L GH+ V S+ + D +Q L+GSSD ++R W+L C +R H E V ++ + +S + I DL N
Sbjct: 107 MSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN-TLTALTASNNTVTTSSLSGN------KDSIYSLAMNQMGTVIVSGSTEKVLRVW-DPRTCAKLMKLKGHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNEAFTHVYSGGRDRKIYCTDLRN 280
BLAST of WD repeat-containing protein 3 vs. Ensembl Xenopus
Match: wdr3 (WD repeat domain 3 [Source:NCBI gene;Acc:394852]) HSP 1 Score: 152.14 bits (383), Expect = 3.506e-70 Identity = 111/440 (25.23%), Postives = 202/440 (45.91%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIYDKIQIDPTAPID------------------PLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA 2811
DL ++L+ V H ++ ++ + D R S GADK + W+ E + S S V Q + V +P+G++ + +D V+ + T DT + L LYGH +PV + + +D+ + G +D++V+ W L GDC + H + V ++++P + FS K + Q D + ++ L GH V L+V +GD +VS S D+S+R W +++ L+ E E+ + + YE E +A+ + +V R+ + + KT+ T + +++MEAI+++ + TA ++ P++ G +VL + +LE L LP +Y L + D + +GR V L RC FL ++HF + + L+ I + + D++G N+A
Sbjct: 478 DLASGNLLETVNAHDGAVWSICPSPDLRGFASGGADKTVRFWDFELVNEETEEQSSRRLS---VKQTRVLQLDEDVLCVRYSPNGRILAVSLLDCTVKVFYT-DTLKFFLSLYGHKLPVLCMDICHDNGLFVPGFADRNVKIWGLDLGDCHRSLFAHEDSVMFLQFVPKTHLFFSAGKDRKVKQWDADHFQQVQTLEGHHGEVWCLAV-----SPNGD-----HVVSSSHDKSLRLWERTREPLILEEEKEMQREAEYE-ESVAKGQQPVVAGEREGEVGLAGKKTIETVKATERIMEAIELHR----EETAKLEEHRALCKAAGKELPHRTHPILQAYGNISPSDYVLDVFKKVKSSELEESLLVLPFSYVSDALALFRDYIRQGRDVELICRCLFFLLRIHFGQITSNQMLLGVIEDLKNCTISRVAEVRDMMGVNMA 898 HSP 2 Score: 135.576 bits (340), Expect = 3.506e-70 Identity = 125/518 (24.13%), Postives = 227/518 (43.82%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYE--LXXXXXXXXXXXXYILHNTHQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKK--IDSDPFESTVQE---------------QYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXX----XXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++A +FG+I + +N++F+ R G G VG E V IW+ E V L G+ + V+ L + GL +++GYE G I ++ + + E + + + H +L+ GSKDT + + DV +E G ++L GHK IT+ ++ +K++LISS +D +K+W L + CF+T+ E+W + ++TGS+++ LR W + + K D+D +S + I + G + RE RVV + D T +L + + LE++ L E E+ K+++ + KKA + D +R ++ L I S + L+ ++ + NN++ +++ T + ++ GHR+ + +SDN+A+ + S +WN+S+ + T + A +L +PGDRH +IG K+G
Sbjct: 1 MGLTKQYLRYAASAVFGLIANQKANVAFITLR-GERGRYVAVGACEHVFIWDTRRGEKVLILQGQKQE-VTRLCPSPD---GLSLAVGYEDGSIRIFSLLSGESGITFNGHKAAVTALNYDHLGGRLVSGSKDTDVIVWDVINESGLYRLRGHKDAITQALFLREKNLLISSGKDTLVKWWDLDTQHCFQTMVGHRTEVWGLTLLSEESRVLTGSADSELRAWNISYMKETEDTDGPQSKKSKGPLGEAQEEEEDVEESTEGRILSCQRFGSIMREGRDRVVSLGTDRTRRFLACHGADSVLEVFCALNEEEIAKKMEKKLKRAKKKAKQKSEDAEEEEELKVERCLQDEIQRLGNIKASSKIKSFDLFAGAKGELKAVLLLQNNSLECYSLPAEP-------------TPAGKAECTRTSRLTLGGHRSDVRTLAFSSDNIAVLSASAETVKIWNRSTLQCIRTMPCEY----------------------------ALCSLFVPGDRHVIIGTKSG 472 HSP 3 Score: 52.373 bits (124), Expect = 4.522e-6 Identity = 35/165 (21.21%), Postives = 73/165 (44.24%), Query Frame = 1
Query: 1765 KNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWN-LPHGDCKIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
K ++ + +PDG +G+ D +R + + + + GH VT+++ + +L++GS D V W+ + RGH + +T ++ +++ S K L+ DL + GH V L++++ E + +++ S D +R W
Sbjct: 65 KQEVTRLCPSPDGLSLAVGYEDGSIRIF-SLLSGESGITFNGHKAAVTALNYDHLGGRLVSGSKDTDVIVWDVINESGLYRLRGHKDAITQALFLREKNLLISSGKDTLVKWWDLDTQHCFQTMVGHRTEVWGLTLLS----------EESRVLTGSADSELRAW 218
BLAST of WD repeat-containing protein 3 vs. Ensembl Xenopus
Match: wdr3 (WD repeat domain 3 [Source:NCBI gene;Acc:394852]) HSP 1 Score: 146.362 bits (368), Expect = 5.010e-70 Identity = 111/441 (25.17%), Postives = 201/441 (45.58%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIYDK-------------------IQIDPTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA 2811
DL ++L+ V H ++ ++ + D R S GADK + W+ E + + LS V Q + V +P+G++ + +D V+ + T DT + L LYGH +PV + + +D+ + G +D++V+ W L GDC + H + V ++++P + FS K + Q D + ++ L GH V L+V +GD +VS S D+S+R W +++ L+ E E+ + + YE E +A+ + +V R+ + + KT+ T + +++MEAI+++ + ++ P I PL +VL + +LE L LP +Y L + D + +GR V L RC FL ++HF + + L+ I + + D++G N+A
Sbjct: 463 DLASGNLLETVNAHDGAVWSICPSPDLRGFASGGADKTVRFWDFE-----LVNEETEDRRLS-VKQTRVLQLDEDVLCVRYSPNGRILAVSLLDCTVKVFYT-DTLKFFLSLYGHKLPVLCMDICHDNGLFVPGFADRNVKIWGLDLGDCHRSLFAHEDSVMFLQFVPKTHLFFSAGKDRKVKQWDADHFQQVQTLEGHHGEVWCLAV-----SPNGD-----HVVSSSHDKSLRLWERTREPLILEEEKEMQREAEYE-ESVAKGQQPVVAGEREGEVGLAGKKTIETVKATERIMEAIELHREETAKLEEHRALCKAAGKEVRRVVPLLTIIPLPP-----QPSDYVLDVFKKVKSSELEESLLVLPFSYVSDALALFRDYIRQGRDVELICRCLFFLLRIHFGQITSNQMLLGVIEDLKNCTISRVAEVRDMMGVNMA 880 HSP 2 Score: 140.969 bits (354), Expect = 5.010e-70 Identity = 129/517 (24.95%), Postives = 230/517 (44.49%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYE--LXXXXXXXXXXXXYILHNTHQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKKIDSDPFESTVQEQ----------------YSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXXXXXXXX----DPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++A +FG+I + +N++F+ R G G VG E V IW+ E V L G+ + V+ L + GL +++GYE G I ++ + + E + + + H +L+ GSKDT + + DV +E G ++L GHK IT+ ++ +K++LISS +D +K+W L + CF+T+ E+W + ++TGS+++ LR W + + K S+ + + + I + G + RE RVV + D T +L + + LE++ L E E+ K+++KKLK+A K D VC T SD C+ + S + L+ ++ + NN++ +++ T + ++ GHR+ + +SDN+A+ + S +WN+S+ + T + A +L +PGDRH +IG K+G
Sbjct: 1 MGLTKQYLRYAASAVFGLIANQKANVAFITLR-GERGRYVAVGACEHVFIWDTRRGEKVLILQGQKQE-VTRLCPSPD---GLSLAVGYEDGSIRIFSLLSGESGITFNGHKAAVTALNYDHLGGRLVSGSKDTDVIVWDVINESGLYRLRGHKDAITQALFLREKNLLISSGKDTLVKWWDLDTQHCFQTMVGHRTEVWGLTLLSEESRVLTGSADSELRAWNISYMKEVSNHGPQSKKSKGPLGEAQEEEEDVEESTEGRILSCQRFGSIMREGRDRVVSLGTDRTRRFLACHGADSVLEVFCALNEEEIAKKMEKKLKRAKKKAKQGCPDGGQVC-THSD-------------CRLFSARSFDLFAGAKGELKAVLLLQNNSLECYSLPAEP-------------TPAGKAECTRTSRLTLGGHRSDVRTLAFSSDNIAVLSASAETVKIWNRSTLQCIRTMPCEY----------------------------ALCSLFVPGDRHVIIGTKSG 457 HSP 3 Score: 52.373 bits (124), Expect = 4.855e-6 Identity = 35/165 (21.21%), Postives = 73/165 (44.24%), Query Frame = 1
Query: 1765 KNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWN-LPHGDCKIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
K ++ + +PDG +G+ D +R + + + + GH VT+++ + +L++GS D V W+ + RGH + +T ++ +++ S K L+ DL + GH V L++++ E + +++ S D +R W
Sbjct: 65 KQEVTRLCPSPDGLSLAVGYEDGSIRIF-SLLSGESGITFNGHKAAVTALNYDHLGGRLVSGSKDTDVIVWDVINESGLYRLRGHKDAITQALFLREKNLLISSGKDTLVKWWDLDTQHCFQTMVGHRTEVWGLTLLS----------EESRVLTGSADSELRAW 218
BLAST of WD repeat-containing protein 3 vs. Ensembl Xenopus
Match: wdr3 (WD repeat domain 3 [Source:NCBI gene;Acc:394852]) HSP 1 Score: 145.976 bits (367), Expect = 1.760e-68 Identity = 111/431 (25.75%), Postives = 200/431 (46.40%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIYDKIQIDPTAPIDP-----LMSGKGFTDAGRFVLHTISTIS----GLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA 2811
DL ++L+ V H ++ ++ + D R S GADK + W+ E + S S+ Q + V +P+G++ + +D V+ + T DT + L LYGH +PV + + +D+ + G +D++V+ W L GDC + H + V ++++P + FS K + Q D + ++ L GH V L+V +GD +VS S D+S+R W +++ L+ E E+ + + YE E +A+ + +V R+ + + KT+ T + +++MEAI+++ + TA ++ +GK +L IS LE L LP +Y L + D + +GR V L RC FL ++HF + + L+ I + + D++G N+A
Sbjct: 478 DLASGNLLETVNAHDGAVWSICPSPDLRGFASGGADKTVRFWDFELVNEETEEQSSRRLSVK---QTRVLQLDEDVLCVRYSPNGRILAVSLLDCTVKVFYT-DTLKFFLSLYGHKLPVLCMDICHDNGLFVPGFADRNVKIWGLDLGDCHRSLFAHEDSVMFLQFVPKTHLFFSAGKDRKVKQWDADHFQQVQTLEGHHGEVWCLAV-----SPNGD-----HVVSSSHDKSLRLWERTREPLILEEEKEMQREAEYE-ESVAKGQQPVVAGEREGEVGLAGKKTIETVKATERIMEAIELHR----EETAKLEEHRALCKAAGKELPHRTHPILQAYGNISVRKICSSLEESLLVLPFSYVSDALALFRDYIRQGRDVELICRCLFFLLRIHFGQITSNQMLLGVIEDLKNCTISRVAEVRDMMGVNMA 889 HSP 2 Score: 135.961 bits (341), Expect = 1.760e-68 Identity = 125/518 (24.13%), Postives = 227/518 (43.82%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYE--LXXXXXXXXXXXXYILHNTHQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKK--IDSDPFESTVQE---------------QYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXX----XXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++A +FG+I + +N++F+ R G G VG E V IW+ E V L G+ + V+ L + GL +++GYE G I ++ + + E + + + H +L+ GSKDT + + DV +E G ++L GHK IT+ ++ +K++LISS +D +K+W L + CF+T+ E+W + ++TGS+++ LR W + + K D+D +S + I + G + RE RVV + D T +L + + LE++ L E E+ K+++ + KKA + D +R ++ L I S + L+ ++ + NN++ +++ T + ++ GHR+ + +SDN+A+ + S +WN+S+ + T + A +L +PGDRH +IG K+G
Sbjct: 1 MGLTKQYLRYAASAVFGLIANQKANVAFITLR-GERGRYVAVGACEHVFIWDTRRGEKVLILQGQKQE-VTRLCPSPD---GLSLAVGYEDGSIRIFSLLSGESGITFNGHKAAVTALNYDHLGGRLVSGSKDTDVIVWDVINESGLYRLRGHKDAITQALFLREKNLLISSGKDTLVKWWDLDTQHCFQTMVGHRTEVWGLTLLSEESRVLTGSADSELRAWNISYMKETEDTDGPQSKKSKGPLGEAQEEEEDVEESTEGRILSCQRFGSIMREGRDRVVSLGTDRTRRFLACHGADSVLEVFCALNEEEIAKKMEKKLKRAKKKAKQKSEDAEEEEELKVERCLQDEIQRLGNIKASSKIKSFDLFAGAKGELKAVLLLQNNSLECYSLPAEP-------------TPAGKAECTRTSRLTLGGHRSDVRTLAFSSDNIAVLSASAETVKIWNRSTLQCIRTMPCEY----------------------------ALCSLFVPGDRHVIIGTKSG 472 HSP 3 Score: 52.373 bits (124), Expect = 4.626e-6 Identity = 35/165 (21.21%), Postives = 73/165 (44.24%), Query Frame = 1
Query: 1765 KNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWN-LPHGDCKIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
K ++ + +PDG +G+ D +R + + + + GH VT+++ + +L++GS D V W+ + RGH + +T ++ +++ S K L+ DL + GH V L++++ E + +++ S D +R W
Sbjct: 65 KQEVTRLCPSPDGLSLAVGYEDGSIRIF-SLLSGESGITFNGHKAAVTALNYDHLGGRLVSGSKDTDVIVWDVINESGLYRLRGHKDAITQALFLREKNLLISSGKDTLVKWWDLDTQHCFQTMVGHRTEVWGLTLLS----------EESRVLTGSADSELRAW 218
BLAST of WD repeat-containing protein 3 vs. Ensembl Xenopus
Match: wdr3 (WD repeat domain 3 [Source:NCBI gene;Acc:394852]) HSP 1 Score: 140.198 bits (352), Expect = 2.304e-67 Identity = 110/429 (25.64%), Postives = 198/429 (46.15%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIYDKIQIDPTAPIDP-----LMSGKGFTDAG--RFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA 2811
DL ++L+ V H ++ ++ + D R S GADK + W+ E + S S+ Q + V +P+G++ + +D V+ + T DT + L LYGH +PV + + +D+ + G +D++V+ W L GDC + H + V ++++P + FS K + Q D + ++ L GH V L+V +GD +VS S D+S+R W +++ L+ E E+ + + YE E +A+ + +V + + + + TER +MEAI+++ + TA ++ +GK G +VL + +LE L LP +Y L + D + +GR V L RC FL ++HF + + L+ I + + D++G N+A
Sbjct: 453 DLASGNLLETVNAHDGAVWSICPSPDLRGFASGGADKTVRFWDFELVNEETEEQSSRRLSVK---QTRVLQLDEDVLCVRYSPNGRILAVSLLDCTVKVFYT-DTLKFFLSLYGHKLPVLCMDICHDNGLFVPGFADRNVKIWGLDLGDCHRSLFAHEDSVMFLQFVPKTHLFFSAGKDRKVKQWDADHFQQVQTLEGHHGEVWCLAV-----SPNGD-----HVVSSSHDKSLRLWERTREPLILEEEKEMQREAEYE-ESVAKGQQPVVSRTWGDTLPINSCCPLQTER----IMEAIELHR----EETAKLEEHRALCKAAGKEVRRGGPSDYVLDVFKKVKSSELEESLLVLPFSYVSDALALFRDYIRQGRDVELICRCLFFLLRIHFGQITSNQMLLGVIEDLKNCTISRVAEVRDMMGVNMA 858 HSP 2 Score: 137.887 bits (346), Expect = 2.304e-67 Identity = 128/514 (24.90%), Postives = 228/514 (44.36%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYE--LXXXXXXXXXXXXYILHNTHQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKK--IDSDPFESTVQE---------------QYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++A +FG+I + +N++F+ R G G VG E V IW+ E V L G+ + V+ L + GL +++GYE G I ++ + + E + + + H +L+ GSKDT + + DV +E G ++L GHK IT+ ++ +K++LISS +D +K+W L + CF+T+ E+W + ++TGS+++ LR W + + K D+D +S + I + G + RE RVV + D T +L + + LE++ L E E+ K+++KKLK+A K ASD C+ + S + L+ ++ + NN++ +++ T + ++ GHR+ + +SDN+A+ + S +WN+S+ + T + A +L +PGDRH +IG K+G
Sbjct: 1 MGLTKQYLRYAASAVFGLIANQKANVAFITLR-GERGRYVAVGACEHVFIWDTRRGEKVLILQGQKQE-VTRLCPSPD---GLSLAVGYEDGSIRIFSLLSGESGITFNGHKAAVTALNYDHLGGRLVSGSKDTDVIVWDVINESGLYRLRGHKDAITQALFLREKNLLISSGKDTLVKWWDLDTQHCFQTMVGHRTEVWGLTLLSEESRVLTGSADSELRAWNISYMKETEDTDGPQSKKSKGPLGEAQEEEEDVEESTEGRILSCQRFGSIMREGRDRVVSLGTDRTRRFLACHGADSVLEVFCALNEEEIAKKMEKKLKRAKKK--------CHASD-------------CRLFSARSFDLFAGAKGELKAVLLLQNNSLECYSLPAEP-------------TPAGKAECTRTSRLTLGGHRSDVRTLAFSSDNIAVLSASAETVKIWNRSTLQCIRTMPCEY----------------------------ALCSLFVPGDRHVIIGTKSG 447 HSP 3 Score: 51.9878 bits (123), Expect = 5.205e-6 Identity = 35/165 (21.21%), Postives = 73/165 (44.24%), Query Frame = 1
Query: 1765 KNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWN-LPHGDCKIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
K ++ + +PDG +G+ D +R + + + + GH VT+++ + +L++GS D V W+ + RGH + +T ++ +++ S K L+ DL + GH V L++++ E + +++ S D +R W
Sbjct: 65 KQEVTRLCPSPDGLSLAVGYEDGSIRIF-SLLSGESGITFNGHKAAVTALNYDHLGGRLVSGSKDTDVIVWDVINESGLYRLRGHKDAITQALFLREKNLLISSGKDTLVKWWDLDTQHCFQTMVGHRTEVWGLTLLS----------EESRVLTGSADSELRAW 218
BLAST of WD repeat-containing protein 3 vs. Ensembl Xenopus
Match: wdr3 (WD repeat domain 3 [Source:NCBI gene;Acc:394852]) HSP 1 Score: 135.961 bits (341), Expect = 2.876e-65 Identity = 125/518 (24.13%), Postives = 227/518 (43.82%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYE--LXXXXXXXXXXXXYILHNTHQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKK--IDSDPFESTVQE---------------QYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXX----XXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++A +FG+I + +N++F+ R G G VG E V IW+ E V L G+ + V+ L + GL +++GYE G I ++ + + E + + + H +L+ GSKDT + + DV +E G ++L GHK IT+ ++ +K++LISS +D +K+W L + CF+T+ E+W + ++TGS+++ LR W + + K D+D +S + I + G + RE RVV + D T +L + + LE++ L E E+ K+++ + KKA + D +R ++ L I S + L+ ++ + NN++ +++ T + ++ GHR+ + +SDN+A+ + S +WN+S+ + T + A +L +PGDRH +IG K+G
Sbjct: 1 MGLTKQYLRYAASAVFGLIANQKANVAFITLR-GERGRYVAVGACEHVFIWDTRRGEKVLILQGQKQE-VTRLCPSPD---GLSLAVGYEDGSIRIFSLLSGESGITFNGHKAAVTALNYDHLGGRLVSGSKDTDVIVWDVINESGLYRLRGHKDAITQALFLREKNLLISSGKDTLVKWWDLDTQHCFQTMVGHRTEVWGLTLLSEESRVLTGSADSELRAWNISYMKETEDTDGPQSKKSKGPLGEAQEEEEDVEESTEGRILSCQRFGSIMREGRDRVVSLGTDRTRRFLACHGADSVLEVFCALNEEEIAKKMEKKLKRAKKKAKQKSEDAEEEEELKVERCLQDEIQRLGNIKASSKIKSFDLFAGAKGELKAVLLLQNNSLECYSLPAEP-------------TPAGKAECTRTSRLTLGGHRSDVRTLAFSSDNIAVLSASAETVKIWNRSTLQCIRTMPCEY----------------------------ALCSLFVPGDRHVIIGTKSG 472 HSP 2 Score: 135.191 bits (339), Expect = 2.876e-65 Identity = 106/428 (24.77%), Postives = 195/428 (45.56%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEA---IDIYDKIQIDPTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIAHFK 2820
DL ++L+ V H ++ ++ + D R S GADK + W+ E + S S V Q + V +P+G++ + +D V+ + T DT + L LYGH +PV + + +D+ + G +D++V+ W L GDC + H + V ++++P + FS K + Q D + ++ L GH V L+V +GD +VS S D+S+R W +++ L+ E E+ + + YE E +A+ + +V R+ + + KT+ T + + + A + + + + P+ + P + G + I + LE L LP +Y L + D + +GR V L RC FL ++HF + + L+ I + + D++G N+A +
Sbjct: 478 DLASGNLLETVNAHDGAVWSICPSPDLRGFASGGADKTVRFWDFELVNEETEEQSSRRLS---VKQTRVLQLDEDVLCVRYSPNGRILAVSLLDCTVKVFYT-DTLKFFLSLYGHKLPVLCMDICHDNGLFVPGFADRNVKIWGLDLGDCHRSLFAHEDSVMFLQFVPKTHLFFSAGKDRKVKQWDADHFQQVQTLEGHHGEVWCLAV-----SPNGD-----HVVSSSHDKSLRLWERTREPLILEEEKEMQREAEYE-ESVAKGQQPVVAGEREGEVGLAGKKTIETVKAVSRSLRAPPTLMEWGSLHL-PSQHMLPHRTHPILQAYGNISVRKICS----SLEESLLVLPFSYVSDALALFRDYIRQGRDVELICRCLFFLLRIHFGQITSNQMLLGVIEDLKNCTISRVAEVRDMMGVNMAALQ 885 HSP 3 Score: 52.373 bits (124), Expect = 4.984e-6 Identity = 35/165 (21.21%), Postives = 73/165 (44.24%), Query Frame = 1
Query: 1765 KNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWN-LPHGDCKIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
K ++ + +PDG +G+ D +R + + + + GH VT+++ + +L++GS D V W+ + RGH + +T ++ +++ S K L+ DL + GH V L++++ E + +++ S D +R W
Sbjct: 65 KQEVTRLCPSPDGLSLAVGYEDGSIRIF-SLLSGESGITFNGHKAAVTALNYDHLGGRLVSGSKDTDVIVWDVINESGLYRLRGHKDAITQALFLREKNLLISSGKDTLVKWWDLDTQHCFQTMVGHRTEVWGLTLLS----------EESRVLTGSADSELRAW 218
BLAST of WD repeat-containing protein 3 vs. Ensembl Mouse
Match: Wdr3 (WD repeat domain 3 [Source:MGI Symbol;Acc:MGI:2443143]) HSP 1 Score: 163.696 bits (413), Expect = 1.463e-78 Identity = 133/462 (28.79%), Postives = 224/462 (48.48%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDT-GINVLT-IKTMNTERNADKLMEAIDIY--------DKIQIDPTA------PIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA---HFKRHMKLMGPELLTFTEQRS 2874
DL ++L+ + H ++ ++ L+ DQR ++ GADK + W+ E +T +S LS V Q + V+ +P+ KL + +D V+ + DT + L LYGH +PV + + +D + + TGS+D++V+ W L GDC + H + V ++++P + F+ K I Q D I L GH Q + L+V G +VS S D+S+R W +++ L+ E E+ + + YE E +A+E V P +T G N T KT+ T + A+++MEAI+++ + I A P++P++ G +VL T I +LE L LP +Y +L + + + G V L RC FL ++HF + + LVP I K+ + +++ D IGFN+A + KR + E++ F E S
Sbjct: 481 DLASGTLLETIAAHDGALWSMSLSPDQRGFVTGGADKAVKFWDFEL----VTDKNSTQKRLS-VKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKVFYV-DTLKFFLSLYGHKLPVLCMDISHDGALIATGSADRNVKIWGLDFGDCHRSLFAHDDSVMYLRFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDY----------VVSASHDKSLRLWERTREPLILEEEREMQREAEYE-ESVAKEDQPAV--PGETQGDNYFTGKKTIETVKAAERIMEAIELHREETAKMKEHRAICKAAGKEVPLPVNPILMAHGNISPSAYVLETFKGIRSSELEEALLVLPFSYVPDVLTLFNEFIQTGLDVELLCRCLFFLLRIHFGQITSNQMLVPVIEKLKETTISKVRQVQDAIGFNMAGLDYLKRECEAKS-EVMFFAEATS 922 HSP 2 Score: 151.369 bits (381), Expect = 1.463e-78 Identity = 134/529 (25.33%), Postives = 245/529 (46.31%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNT--HQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKKIDSDPFESTVQE-QYSNAIQATP----------------------VPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXX--------XXXXXXDP-ANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++ +FG+IG + NI F+ R G G V E V IW+L E + L G + V+ L + GLH+++GYE G I ++ + + E ++ HK +++ + ++ +L GSKDT + I DV +E G ++L+GHK +T+ ++ ++++L++S +D +K+W L + CFKT+ E+W L+TG++++ LR W +D+ + DP E ++ + IQ TP G + RE RVV + +D+TG L + + LE++ +L++AE++K++ KKLKK +A + DP +V +T D + + I+ + K + P+ + K L + NN + ++++ S + + I+ GHR+ + +SDN+A+ + + +WN+S+ + T + A + +PGDR +IG K G
Sbjct: 1 MGLTKQYLRYVASAVFGLIGSQKGNIVFVTLR-GEKGRYVAVPACEHVFIWDLRKGEKILILQGNKQE-VTCLCPSPD---GLHLAVGYEDGAIRIFSLLSGEGNITFNGHKAAVTSLKYDQLGGRLASGSKDTDVIIWDVINESGLYRLKGHKDAVTQALFLRERNLLVTSGKDTMVKWWDLDNQHCFKTMVGHRTEVWGLVLVSEEKRLITGAADSELRAWDIDYLQEIDDPEEPEPKKIKECPGIQDTPESEDSTLEADDEKSEDRILSCSKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLEVFCILSKAEVQKKMDKKLKKARKKARLNSANEEEDPETSVSMTLQDEILRVAKIKTSAKIKSFDLIHSPQGELKAVFL-----LQNNLVELYSLNAS----------------LPAPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMPCEY----------------------------ALCSFFVPGDRQVVIGTKTG 475 HSP 3 Score: 51.6026 bits (122), Expect = 5.901e-6 Identity = 41/168 (24.40%), Postives = 76/168 (45.24%), Query Frame = 1
Query: 1765 KNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYD--SSQLLTGSSDKSVRSWNLPHGDCKIFR--GHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
K ++ + +PDG +G+ D +R + + + + GH VTS+ KYD +L +GS D V W++ + + ++R GH + VT ++ R++ + K ++ DL N + GH V L +V+ E L++ + D +R W
Sbjct: 65 KQEVTCLCPSPDGLHLAVGYEDGAIRIF-SLLSGEGNITFNGHKAAVTSL--KYDQLGGRLASGSKDTDVIIWDVIN-ESGLYRLKGHKDAVTQALFLRERNLLVTSGKDTMVKWWDLDNQHCFKTMVGHRTEVWGLVLVS----------EEKRLITGAADSELRAW 218
BLAST of WD repeat-containing protein 3 vs. Ensembl Mouse
Match: Taf5 (TATA-box binding protein associated factor 5 [Source:MGI Symbol;Acc:MGI:2442144]) HSP 1 Score: 66.6254 bits (161), Expect = 1.290e-10 Identity = 57/256 (22.27%), Postives = 107/256 (41.80%), Query Frame = 1
Query: 1546 VDLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEEND 2310
+D S L+ + H+ + + D+ +LS+ D + +W+++ + C + + +P G F+ G D R + TD + + GH V +S+ + TGS+D++VR W++ +G+C +IF GH P+ + + P + G ++ D+ + + L+GH +V SL DG+ L S S D ++R W V+ E +E +D
Sbjct: 529 MDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ----------------TFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLW-ATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF-----SRDGE-----ILASGSMDNTVRLW-----DAVKAFEDLETDD 752 HSP 2 Score: 56.6102 bits (135), Expect = 1.518e-7 Identity = 42/130 (32.31%), Postives = 57/130 (43.85%), Query Frame = 1
Query: 1762 FKNA---ISSVAVTPDGKLFIIGFMDSKVRTYLTT---------------------DTSRRVLD---------LYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKI-FRGHTEPVTDVKYIP 2049
F NA +++V VT D L GF DS VR + T D R++D LYGHS PV S D + LL+ S D +VR W+L C + ++GH PV D ++ P
Sbjct: 467 FLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 596
BLAST of WD repeat-containing protein 3 vs. Ensembl Mouse
Match: Rack1 (receptor for activated C kinase 1 [Source:MGI Symbol;Acc:MGI:101849]) HSP 1 Score: 63.1586 bits (152), Expect = 4.896e-10 Identity = 69/276 (25.00%), Postives = 116/276 (42.03%), Query Frame = 1
Query: 1579 VKRHTESISALVLT-QDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTY-LTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIF---RGHTEPVTDVKYIPGRS--MAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGT-----------------------EADGDELENAELVS-------VSTDRSIRFWYESQDILVREVEQ 2295
+K H ++ + T Q +LSA DK ++MW + T I Q + +S V ++ DG+ + G D +R + LTT T+ R GH+ V S++ D+ Q+++GS DK+++ WN G CK H+E V+ V++ P S + SC L+ +L N GH +++++V G+ DG ++ NA S +T SI+ W I+V E++Q
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIP-----------QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR--RFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQ 272
BLAST of WD repeat-containing protein 3 vs. Ensembl Mouse
Match: Wdr48 (WD repeat domain 48 [Source:MGI Symbol;Acc:MGI:1914811]) HSP 1 Score: 64.6994 bits (156), Expect = 5.277e-10 Identity = 47/179 (26.26%), Postives = 91/179 (50.84%), Query Frame = 1
Query: 1579 VKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHN 2112
++ H + + AL +D+ V SAG D+ + +W++ + TA+T +++ + SL K++I S+A+ G + + G + +R + T +++ L GH+ V ++ + D +Q L+GSSD ++R W+L C +R H E V ++ + +S + I DL N
Sbjct: 113 LRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN-TLTALTASNNTVTTSSLSGN------KDSIYSLAMNQLGTIIVSGSTEKVLRVW-DPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRN 283
BLAST of WD repeat-containing protein 3 vs. Ensembl Mouse
Match: Wdr48 (WD repeat domain 48 [Source:MGI Symbol;Acc:MGI:1914811]) HSP 1 Score: 64.3142 bits (155), Expect = 5.528e-10 Identity = 47/182 (25.82%), Postives = 92/182 (50.55%), Query Frame = 1
Query: 1570 LQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHN 2112
+ ++ H + + AL +D+ V SAG D+ + +W++ + TA+T +++ + SL K++I S+A+ G + + G + +R + T +++ L GH+ V ++ + D +Q L+GSSD ++R W+L C +R H E V ++ + +S + I DL N
Sbjct: 110 MSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN-TLTALTASNNTVTTSSLSGN------KDSIYSLAMNQLGTIIVSGSTEKVLRVW-DPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRN 283
BLAST of WD repeat-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q8BHB4|WDR3_MOUSE (WD repeat-containing protein 3 OS=Mus musculus OX=10090 GN=Wdr3 PE=1 SV=1) HSP 1 Score: 163.696 bits (413), Expect = 8.921e-78 Identity = 133/462 (28.79%), Postives = 224/462 (48.48%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDT-GINVLT-IKTMNTERNADKLMEAIDIY--------DKIQIDPTA------PIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA---HFKRHMKLMGPELLTFTEQRS 2874
DL ++L+ + H ++ ++ L+ DQR ++ GADK + W+ E +T +S LS V Q + V+ +P+ KL + +D V+ + DT + L LYGH +PV + + +D + + TGS+D++V+ W L GDC + H + V ++++P + F+ K I Q D I L GH Q + L+V G +VS S D+S+R W +++ L+ E E+ + + YE E +A+E V P +T G N T KT+ T + A+++MEAI+++ + I A P++P++ G +VL T I +LE L LP +Y +L + + + G V L RC FL ++HF + + LVP I K+ + +++ D IGFN+A + KR + E++ F E S
Sbjct: 481 DLASGTLLETIAAHDGALWSMSLSPDQRGFVTGGADKAVKFWDFEL----VTDKNSTQKRLS-VKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKVFYV-DTLKFFLSLYGHKLPVLCMDISHDGALIATGSADRNVKIWGLDFGDCHRSLFAHDDSVMYLRFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDY----------VVSASHDKSLRLWERTREPLILEEEREMQREAEYE-ESVAKEDQPAV--PGETQGDNYFTGKKTIETVKAAERIMEAIELHREETAKMKEHRAICKAAGKEVPLPVNPILMAHGNISPSAYVLETFKGIRSSELEEALLVLPFSYVPDVLTLFNEFIQTGLDVELLCRCLFFLLRIHFGQITSNQMLVPVIEKLKETTISKVRQVQDAIGFNMAGLDYLKRECEAKS-EVMFFAEATS 922 HSP 2 Score: 151.369 bits (381), Expect = 8.921e-78 Identity = 134/529 (25.33%), Postives = 245/529 (46.31%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNT--HQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKKIDSDPFESTVQE-QYSNAIQATP----------------------VPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXX--------XXXXXXDP-ANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++ +FG+IG + NI F+ R G G V E V IW+L E + L G + V+ L + GLH+++GYE G I ++ + + E ++ HK +++ + ++ +L GSKDT + I DV +E G ++L+GHK +T+ ++ ++++L++S +D +K+W L + CFKT+ E+W L+TG++++ LR W +D+ + DP E ++ + IQ TP G + RE RVV + +D+TG L + + LE++ +L++AE++K++ KKLKK +A + DP +V +T D + + I+ + K + P+ + K L + NN + ++++ S + + I+ GHR+ + +SDN+A+ + + +WN+S+ + T + A + +PGDR +IG K G
Sbjct: 1 MGLTKQYLRYVASAVFGLIGSQKGNIVFVTLR-GEKGRYVAVPACEHVFIWDLRKGEKILILQGNKQE-VTCLCPSPD---GLHLAVGYEDGAIRIFSLLSGEGNITFNGHKAAVTSLKYDQLGGRLASGSKDTDVIIWDVINESGLYRLKGHKDAVTQALFLRERNLLVTSGKDTMVKWWDLDNQHCFKTMVGHRTEVWGLVLVSEEKRLITGAADSELRAWDIDYLQEIDDPEEPEPKKIKECPGIQDTPESEDSTLEADDEKSEDRILSCSKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLEVFCILSKAEVQKKMDKKLKKARKKARLNSANEEEDPETSVSMTLQDEILRVAKIKTSAKIKSFDLIHSPQGELKAVFL-----LQNNLVELYSLNAS----------------LPAPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMPCEY----------------------------ALCSFFVPGDRQVVIGTKTG 475
BLAST of WD repeat-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q9UNX4|WDR3_HUMAN (WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1) HSP 1 Score: 157.918 bits (398), Expect = 1.016e-76 Identity = 123/437 (28.15%), Postives = 208/437 (47.60%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLT-IKTMNTERNADKLMEAIDIY--------DKIQIDPTA------PIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA 2811
DL ++L+ + H ++ ++ L+ DQR ++ GADK + W+ E + +S LS V Q + V+ +P+ KL + +D V+ + DT + L LYGH +PV + + +D + + TGS+D++V+ W L GDC K H + V ++++P + F+ K I Q D I L GH Q + L+V G +VS S D+S+R W +++ L+ E E+ E + YE+ ++ + G + G + T KT+ T + A+++MEAI++Y + I A P +P++ G +VL I +LE L LP +Y +L + + + G V L RC FL ++HF + + LVP I K+ + + + DVIGFN+A
Sbjct: 482 DLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFEL----VKDENSTQKRLS-VKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYV-DTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDY----------VVSSSHDKSLRLWERTREPLILEEEREMEREAEYEESVAKEDQPAVPGETQ--GDSYFTGKKTIETVKAAERIMEAIELYREETAKMKEHKAICKAAGKEVPLPSNPILMAYGSISPSAYVLEIFKGIKSSELEESLLVLPFSYVPDILKLFNEFIQLGSDVELICRCLFFLLRIHFGQITSNQMLVPVIEKLRETTISKVSQVRDVIGFNMA 900 HSP 2 Score: 153.68 bits (387), Expect = 1.016e-76 Identity = 138/530 (26.04%), Postives = 244/530 (46.04%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNT--HQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKKIDSDPFESTVQ-------------EQYSNAIQATPVP----------GEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXX---------XXXXXXXDP-ANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++ +FGVIG + NI F+ R G G V E V IW+L E + L G + +V+ L + GLH+++GYE G I ++ + + E V+ HK +I+ + ++ +L GSKDT I + DV +E G ++L+GHK IT+ ++ +K++L++S +D +K+W L + CFKT+ E+W L+TG+S++ LR+W + + + DP E + E A + P G + RE RVV + +D+TG L + + LEL+ +L++ E++K++ KK+K + + DP NV ++ D ++ + I+ + K + P + K L + NN + ++++ S + T + I+ GHR+ + +SDN+A+ + + +WN+S+ + T T +Y A + +PGDR +IG K G
Sbjct: 1 MGLTKQYLRYVASAVFGVIGSQKGNIVFVTLR-GEKGRYVAVPACEHVFIWDLRKGEKILILQG-LKQEVTCLCPSPD---GLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIEDPEEPDPKKIKGSSPGIQDTLEAEDGAFETDEAPEDRILSCRKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLELFCILSKKEIQKKMDKKMKKARKKAKLHSSKGEEEDPEVNVEMSLQDEIQRVTNIKTSAKIKSFDLIHSPHGELKAVFL-----LQNNLVELYSLNPS----------------LPTPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTM--TCEY--------------------------ALCSFFVPGDRQVVIGTKTG 476
BLAST of WD repeat-containing protein 3 vs. UniProt/SwissProt
Match: sp|P87177|YB1C_SCHPO (Uncharacterized WD repeat-containing protein C3D6.12 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPBC3D6.12 PE=1 SV=1) HSP 1 Score: 135.576 bits (340), Expect = 4.933e-31 Identity = 114/444 (25.68%), Postives = 205/444 (46.17%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMAR-ERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAI-----DIYDKIQI---------DPTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA--HFKRH 2826
D+ S+++ ++ H +I L + D +A AD + +W+++ S + +L L Q F + + +V ++PDG+ +D+ V+ Y D+ + L+LYGH +PV S+ + YDS L+T S+DK+V+ W L GDC K H + + +V + P F+C K + D + I++LRGH V +L+V G +VS S D SIR W + D++ E E+ E + YE ++ E G +D + +T +T+ + ++ +K++EAI D+ +IQ P +P+++ G + A +VL+T I L+ L LP + L + ++ + L +R FL + + + + P + + + LQ +IG+N A + RH
Sbjct: 463 DIASSSLIERIQAHDGAIWDLAVGHDGTYFATASADHTVKLWSLKSSFDFVPGTTRKVTTLKLE-QTRQIDFTDDVLAVKISPDGRFVAASLLDNTVKVYYL-DSLKFFLNLYGHKLPVLSMDISYDSKLLVTCSADKNVKIWGLDFGDCHKSIFAHQDSIMEVTFQPDTYNFFTCSKDREVRYWDGKSFDLILKLRGHHSEVWALAV--------GPTF----VVSGSHDHSIRLWEQGDDLVFLEEERERELEEQYESTLVSSYENAEADGEVKDGDVAAVTKQTIESLKDGEKILEAITIGIEDLDQEIQYRLDLLKSPGKARGPRNPILAHLGVS-AEEYVLNTFKKIRSSHLDDALLVLPFEHVLSLFRFIDIWASRKWSIPLVSRIIFFLLRTYHRQLTTTVKMRPLLNNIRSSLRGSLQEERSLIGYNAAGLSYLRH 891 HSP 2 Score: 94.7449 bits (234), Expect = 2.186e-18 Identity = 113/466 (24.25%), Postives = 189/466 (40.56%), Query Frame = 2
Query: 62 IVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNTHQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYI---------------------------SKKDVLISSSQDGEIKFWFLSLKRCFKT-LTTSIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKKIDSDPFESTVQEQYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRAS----ISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSST 1360
+VK+Y ++ FGVI NI P+ +VG E V+ W+L T +++ K D T F ++GY G I ++ + ++ + +L GS DT I + D+ E G F+L GHK ITKL +I S L+S +D +K W LS++ C +T + EIW +T + + +++W + F D + F T + A Q G R+S R + + D + Y+V A ++ LE++R+ + AEL+K L ++ ++ +V IT D + +I R VA +P + L+ S+ NN+I V+ + + S+ LT RAS I GHR + L++++ I + + LWNK +T
Sbjct: 1 MVKSYTRYEPTEFFGVIASSGCNILGQPSSSAKSVGRAIVGGLESVLEWDLKTGQLL----SKWKDSDCSAKVTCIANFDEMYAVGYADGSIRLWKDGELLITLNGHKSAVTTMDFDKMGTRLASGSMDTDIIVWDIVAETGLFRLRGHKDQITKLLFITPPSKNTAEETVVDTDIDSGDMDVDSKSSDSFLLSVGKDSFMKLWDLSIQHCVETHVDHQGEIWAMCVSPDAKRCLTAGTGSDVKVWEISFP--DDNNFTPTTK-----AFQQL---GTFTRQSRDRPITLAYDVSNRYVVFQAHDRLLEVFRLRSSAELEKILNRRRRRKKSE-----DVSITLKDEYEPFALIRTTARASSVAW--IPGNRTP----TLVTSLQNNSIEVYALDVKSEGS--------------AAPLTERASRISAIEIPGHRADVRTLALSANHDVILSGANGSLKLWNKKTT 427
BLAST of WD repeat-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q54S79|WDR3_DICDI (WD repeat-containing protein 3 homolog OS=Dictyostelium discoideum OX=44689 GN=wdr3 PE=3 SV=1) HSP 1 Score: 127.102 bits (318), Expect = 2.307e-28 Identity = 118/445 (26.52%), Postives = 198/445 (44.49%), Query Frame = 1
Query: 1579 VKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEK--EEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAID--IYDKIQID---------------PTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLL---LNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFN---IAHFKRHMKL 2835
+K H S+ +LVLT D R V S GADK + W+ E ++ H N LSL E + + ++ + D K + +D+ V+ + T DT + L LYGH +PV + + DS+ ++TGS+DK+++ W L +GDC K F H + + V +IP S K I D I + H V SL AMG+ D +S S DRSIR + +++ + E ++ E ++ +E E+ R R + +T+ T + +++AI+ + +K +ID P + +M G ++ + I+ I DLE L LP + + L N+ DQ G+ V +C FL + H + +P + + K LQ+ +GFN ++ KR +++
Sbjct: 473 IKAHEGSVWSLVLTPDLRGVTSGGADKLVKFWDFELIASQENSKHKVLN-LSLTKTLKVE---SDVLALKYSADNKFLAVSLLDNTVKIFYT-DTVKFHLSLYGHKLPVMCLDISDDSTLIITGSADKNIKIWGLDYGDCHKSFFAHDDSIMQVSFIPSTHHFISASKDKRIKYWDADKFEHIQTIEAHHGEVWSL---AMGSVGDF-------FISGSHDRSIRIFNQTETPIFVESDRQREMEQTWEATLEDDTRMRTKEMLEENAAAGK----QTLETIMAGEDILDAIELCVQEKFKIDEYEKLLKTTKNQDEIPLYQPNIIMLG---LSPSEYLWNRINRIRPSDLEEALRVLPFSVMRTLFEYFNLWVDQ--SGKSVEFIFKCSFFLIQTHQNQLSVSTEFIPILQHLNTSIKNRLQKERFTLGFNRSALSFVKREIEI 893 HSP 2 Score: 92.4337 bits (228), Expect = 1.218e-17 Identity = 76/268 (28.36%), Postives = 135/268 (50.37%), Query Frame = 2
Query: 62 IVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGK-MDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNT--HQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTTSIE-IWDFFYCDTRNLLVTGSSETTLRLWRLDFKKIDSDPFESTVQEQYSNAIQATP------VPGEVNRESPKR 832
+VK YLKF D +FG+I NS + DG+ G L + G E + IW+L Q + ++L+ + + +V+ + + G ++ GY G I ++ +S Y+L H+ S++ + N + L+ GSKDT + + D+ E G F+L GH+ IT + + + + LI+SS+DG IK W + C +T+ IW L + +S+ +R WR+ + + S ++ ++ I TP +P E+N + K+
Sbjct: 1 MVKAYLKFVQDKVFGLISTSNSIL------DGS-GKLAITGCGERISIWDLRKQVLNQSLYEEDIKAEVTNVCLSKD---GALLASGYSDGSIRIWSMSDYQLQAVFNGHRGSVTTMTFNRLGNILVSGSKDTEVIVWDIITESGLFRLRGHRDQITSVKLLERSNHLITSSKDGFIKIWDTETQHCIQTIVGHRNPIWGIDVNPDETRLCSCTSDNQIRFWRIPSNERQRED-GSGIEPKF---IVNTPINSAVIIPDEINEDGSKK 254
BLAST of WD repeat-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q12220|UTP12_YEAST (U3 small nucleolar RNA-associated protein 12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DIP2 PE=1 SV=1) HSP 1 Score: 117.087 bits (292), Expect = 2.734e-25 Identity = 112/466 (24.03%), Postives = 209/466 (44.85%), Query Frame = 1
Query: 1549 DLVVESVLQYVK-RHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEK------EEMARERIVIVGAPRD------TGINVLTIKTMNTERNADKLMEAID-----------------IYDKIQIDPTAPIDPLMSGKGFTDA-----GRFVLHTISTISGLDLELILSQLPVTYA----KLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVV--RDPTLVPAITKMAKYAKIYLQRNVDVIGFNIAHFK 2820
DL S+L ++ H +I +L LT D + +++ ADK + W+ + ++ + + + + +T + I V V+PD + I +D+ V+ + D+ + L LYGH +PV SI + +DS ++T S+DK+++ W L GDC K H + + +VK++P FSC K ++ D I +L H V +L+V G +VS S D SIR W E++D + E E+ +E + YE EE + A + +G++ T++++ + ++LMEA+D ++ + ++ API P G A ++++ T+ I LE L +P +Y K + ++ ++ + L + F+ K + +V ++ L I ++ + L+ D +GFN+ K
Sbjct: 458 DLASSSLLDTIEDAHDAAIWSLDLTSDGKRLVTGSADKTVKFWDFKVENSLVPGTKNKFLPVLKLHHDTTLELTDDILCVRVSPDDRYLAISLLDNTVKVFFL-DSMKFYLSLYGHKLPVLSIDISFDSKMIITSSADKNIKIWGLDFGDCHKSLFAHQDSIMNVKFLPQSHNFFSCSKDAVVKYWDGEKFECIQKLYAHQSEVWALAVATDG----------GFVVSSSHDHSIRIWEETEDQVFLEEEKEKELEEQYEDTLLTSLEEGNGDDAFKADASGEGVEDEASGVHKQTLESL---KAGERLMEALDLGIAEIEGLEAYNRDMKLWQRKKLGE-APIKP--QGNAVLIAVNKTPEQYIMDTLLRIRMSQLEDALMVMPFSYVLKFLKFIDTVMQNKTLLHSHLPLICKNLFFIIKFNHKELVSQKNEELKLQINRVKTELRSALKSTEDDLGFNVQGLK 906 HSP 2 Score: 92.8189 bits (229), Expect = 8.226e-18 Identity = 113/459 (24.62%), Postives = 210/459 (45.75%), Query Frame = 2
Query: 62 IVKNYLKFAHDTLFGVIGCENSNISFLP----NRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTL-----------HGKMDDKVSYL-SYTHSDIFGLHISIGYESGYISVYDV--STYELXXXXXXXXXXXXYILHNTHQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKT-LTTSIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKKIDSDPFESTVQEQYSNAIQATPVPGEVNRESPKRVVEMKI-----DETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXXXXXXXXDPANVCITASDR-----LKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWN 1348
+VK+Y +F FGVI N+N ++P N +G+ + EDV IW++ T ++V L G + +YL ++ +D+ +++GY G I V+D+ T L + ++ +LI GSKD+ I + D+ E G +KL HK IT + +D LIS+S+DG IK W L +C +T + + E W D +LL+T +++ +++W+LD I++D + E G ++S +R ++++ D+T + + NA +K +E +R+ E E+ + L+K+ K+ + + + + L + I Y+ K + +V +K LEL+++ +NTI +++ PA + T ++ ++ G RT + ++ DN + T S +WN
Sbjct: 1 MVKSYQRFEQAAAFGVIAS-NANCVWIPASSGNSNGSGPGQLITSALEDVNIWDIKTGDLVSKLSDGLPPGASDARGAKPAECTYLEAHKDTDL----LAVGYADGVIKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDLVGEVGLYKLRSHKDSITGF-WCQGEDWLISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAVKD--DLLITTGTDSQVKIWKLD---IENDKMGGKLTEM-----------GIFEKQSKQRGLKIEFITNSSDKTSFFYIQNA-DKTIETFRIRKEEEIARGLKKREKRLKEKGLTEEEIAKSIKESYSSFILHPFQTIRSLYKIKSASWTTVSSSK-----LELVLTTSSNTIEYYSIPYEK-------RDPTSPAPLKTHTIELQ------GQRTDVRSIDISDDNKLLATASNGSLKIWN 418
BLAST of WD repeat-containing protein 3 vs. TrEMBL
Match: A0A023ZSQ1 (WD repeat-containing protein 3 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 524.242 bits (1349), Expect = 2.175e-177 Identity = 253/253 (100.00%), Postives = 253/253 (100.00%), Query Frame = 1
Query: 2113 MSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIYDKIQIDPTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIAHFKRHMKLMGPELLTFTEQR 2871
MSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIYDKIQIDPTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIAHFKRHMKLMGPELLTFTEQR
Sbjct: 1 MSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIYDKIQIDPTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIAHFKRHMKLMGPELLTFTEQR 253
BLAST of WD repeat-containing protein 3 vs. TrEMBL
Match: A0A3Q0KMK9 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 200.29 bits (508), Expect = 1.448e-95 Identity = 140/512 (27.34%), Postives = 252/512 (49.22%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMD-DKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNTHQLICGSKDTTISIIDVGDERGFKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTTSI-EIWDFFYCDTRNLLVTGSSETTLRLWRLDF-----------KKIDSDPFESTVQEQYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXXXXXXXXDPANVCITASDRLKLLKVIEL---PYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNT-HLEASAALLLPGDRHALIGFKNGVM 1540
+ + Y K+ +G+I +++ +S++ N+ G LC+ G E IIW T E V T +S L + ++IGY G +++++++T ++ + + + ++ + L+C + D+ I++ D+ G +++GH IT++ ++++ +LISS+QD IKFW L + CF TLT +WDF LLV+G+++ LR+W++ + K S+P E+ + A G V R +RV + D TG YL+ + ++ +E++R+L E KRL+KK KK D ++V + A D L+ + I L P C +A V E + ++ + ++ S+ NN + + + + + ++S GHR+ +I C TSDNL +FT+S +EA LW++ ST +T W + N K ++ LS+N +AS+ +L PGDRH +IG++ G +
Sbjct: 1 MKVTHTYQKYNPKAAYGIIASDSTKVSYVSNKSCKSGELCLCGAGESAIIWKPRTSEKVHTFARDTGCHPISCLKASDISSLDPRVAIGYSDGLVNIFNMNTGDIEANFRAGRSRVTSMDLKNDLLVCAA-DSEINVFDIISGSGTRMKGHHGIITQMKLLTERKILISSAQDSFIKFWDLKTQHCFATLTGHPGPVWDFALTRCDELLVSGTNDQNLRVWQIKYVNESDSLVKHNDKTTSNPDEAITPLSEPQSQIAIQFSGCVQRSGVRRVHCLVFDPTGTYLLCQSFDRSVEIFRLLDEEAKAKRLRKKTKKTKAKGLDLSSVILEAEDELRPILKINLSAKPGSCDILAPRLVNEHESQKHLIRIICSLKNNMLEELQLAVPLSPFKLQTLQPTLTYNKKCPNARLLNTVSIFGHRSPVIACSFTSDNLGVFTLSQTEAKLWSRRSTACLATLEW--------KNHSNSKHNNSDEPLSNNPLPNKASSMVLAPGDRHVVIGYETGQL 503 HSP 2 Score: 182.185 bits (461), Expect = 1.448e-95 Identity = 146/466 (31.33%), Postives = 231/466 (49.57%), Query Frame = 1
Query: 1549 DLVVESVLQYV-KRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGT----------------------------EADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGA-PRDTG-INVLTIKTMNTERNADKLMEAIDIYD----KIQIDPTAPIDPLMSGKGFTDAGRFVLHTISTI---------SGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA 2811
DL +SV+Q + + HT ++ ++ +T D++ ++S G+DK + ++ ++ H L LV + + IS +AV+P+ +L ++ M+ V + T D+ +R+ LYGHS PVTS+ + DS ++TGS+DK+VR W L G+C + F H+EP+T V++IP S+A S DK G I Q D+ EI +GH SV+ L+ T + D DEL ++S D SIR W E+ ++L+ E E+ ++ E+EE+ R VI GA P + + L T NT AD MEA+DIY+ K + PLM +G RF+L ++ + G LE L L + + LL LAD +++G ++ L R + L LHF V+ L AI + +K L R ++IG N+A
Sbjct: 507 DLTSKSVVQIIDEAHTGAVRSIAVTGDKKKIISGGSDKQVRFYDFSLKTSDNGKPH-----LCLVESCPSKTVSDQISCLAVSPNNRLVVVALMNFHVDVFFT-DSFKRIHSLYGHSAPVTSLDISSDSRLIITGSTDKTVRLWELQFGNCQRRFTSHSEPITCVRFIPHTSLAVSSDKGGQIKQWDIKKFREITTFKGHNGSVTCLATTITNTALLTQKKTPKLEKTRKSRAQNNQDEGSNDDDMDELWGGLILSTGQDFSIRIWEEADELLILEEEEQIAREQ-EEEEELVRSEAVIPGAMPSEASEVGPLGRPTGNTRDAADMFMEAMDIYEEEIVKRKNGAKNITHPLMVARGTNCPERFLLKSLMALRAPYSRLGGGGAGLEHALGALTSEHVRRLLPKLADWLSRGWEIELVGRSIRHLVTLHFGLVISCSELRDAIRQSSKARMEQLVRAKNLIGMNLA 965
BLAST of WD repeat-containing protein 3 vs. TrEMBL
Match: A0A4Z2DQX6 (WD repeat-containing protein isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_009741 PE=4 SV=1) HSP 1 Score: 200.29 bits (508), Expect = 3.110e-95 Identity = 143/517 (27.66%), Postives = 254/517 (49.13%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTL-HGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYI-LHNTHQLICGSKDTTISIIDVGDERGFKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTTSI-EIWDFFYCDTRNLLVTGSSETTLRLWRLDFKKIDSDPFE-------------STVQEQYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXXXXXXXXDPANVCITASDRLKLLKVIEL---PYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHL---EASAALLLPGDRHALIGFKNGVM 1540
+ + Y ++ +G+I + +S++ + +G LC+ G E IIW T ++V + +S L + + ++IGY G +++ ++ T ++ + + ++ + L N L+ + D+ I++ D+ G +++GH ITK+ + + +LISS+QD IKFW L + CF TLT +WDF +LV+G+++ LR+WR+++ + P S++ E +S + G V R +RV + D TG YL+ + ++ +E++R+L E E KRL+KK+KKA + DP++V + A D L+ + L P C +A + E ++ + + ++ NN + + + S+ + SIS GHR+ +I C TSDNL +FT+S SEA LW++ ST +T W R +DD + +G SS T +AS+ +L PGDRH +IG++ G +
Sbjct: 1 MKVTHTYQRYNPKVSYGIITSDLIKVSYISDNGSKLGDLCLCGAGEKAIIWKPRTSQMVCSFARDTGSSPISCLKVSETSNLDPRVAIGYVDGLVNLVNIKTGDIEAHFRAGRSRVTSMDLQN--DLLISAADSEINVFDIVSGSGTRMKGHHGIITKIKILPVRKILISSAQDSFIKFWDLKTQHCFATLTGHPGPVWDFSLAHHDEILVSGTNDQNLRVWRINYVDENDSPLAHVSKTTSGATETISSLSEPHSQIV--VQFVGCVKRSGVRRVNCLAFDPTGTYLLCQSFDRNVEIFRLLNEEEKAKRLRKKIKKAKEKGLDPSSVTLNAEDELRPFMRVTLSAKPSSCDILAPRLINEHNSQKHLIRFICALRNNVLEELQLAVPLSTFKLQTLQPTSAFTKKCPSVHLLNSISIFGHRSPVIACSFTSDNLGVFTLSRSEAKLWSRRSTACLTTLEWR----RKSDDN------YNNVGESSVTKPLPNKASSMVLAPGDRHVVIGYETGQL 503 HSP 2 Score: 180.644 bits (457), Expect = 3.110e-95 Identity = 145/475 (30.53%), Postives = 224/475 (47.16%), Query Frame = 1
Query: 1549 DLVVESVLQYV-KRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSV----VAMGTEADGDELENAE-----------------------LVSVSTDRSIRFWYESQDI--------LVREVEQMEENDRCYEKEEMARERIVIVGA-PRDTG-INVLTIKTMNTERNADKLMEAIDIYD------KIQIDPTAPIDPLMSGKGFTDAGRFVLHTISTI---------SGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA 2811
DL + ++Q + + H+ ++ ++ +T D++ V+S G+DK + ++ + H L L + + IS +AVTP+ +L +I M+ V + T D+ +R+ LYGHS PVTS+ + DS ++TGS+DK+VR W L G+C + F H EP+T V++IP S+A S D+ G I Q D+ EI L+GH V+ L+ A T +LEN ++S D SIR W E+ ++ +VRE E E++E+ R VI GA P + I L T NT AD MEA+DIY+ K T P PLM +G +F+L ++ + G LE L L + + LL LAD +++G ++ L R + L LHF V+ L I + A L R ++IG N+A
Sbjct: 507 DLTSKLIVQVIDEAHSGAVRSIAVTGDKKTVISGGSDKQVRFYDFHLKTGDNGKPH-----LCLAESSPAKTVSDQISCLAVTPNNRLLVIALMNFHVDVFFT-DSFKRIHSLYGHSAPVTSLDISSDSRLIITGSTDKTVRLWELQFGNCQRRFTSHLEPITCVRFIPHTSLAVSADQGGQIKQWDIKKFREITTLKGHNGGVTCLATTITNTAFLTRKKAPKLENPRKSHTQKNQDEDSDDDMDELRGGLILSTGQDFSIRIWEEADELLILEEEEQIVREQE---------EEDELVRSEAVIPGAIPSEASEIGPLGRPTSNTRDAADMFMEAMDIYEEEIAKRKNNAKNTTP-HPLMIARGTDCPEKFLLKSLMALRAPYSRLGGGGAGLEHTLGALTSDHVRRLLPKLADWLSRGWELELVGRSIRHLVTLHFGLVLSCSELREVIRQSANARTEQLVRVKNLIGMNLA 965
BLAST of WD repeat-containing protein 3 vs. TrEMBL
Match: A0A4E0RYM5 (U3 small nucleolar RNA-associated protein 12 OS=Fasciola hepatica OX=6192 GN=D915_000055 PE=4 SV=1) HSP 1 Score: 195.282 bits (495), Expect = 4.596e-95 Identity = 154/522 (29.50%), Postives = 261/522 (50.00%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQE---IVKTLHGKMDDKVSYLSYTH-SDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNTHQLICGSKDTTISIIDVGDERGFKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRL-----DFKKIDSDPFESTVQEQYSNAIQATPVP-------------GEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRK----EAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKS-LTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDA-DNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+ + K Y + D +FG+I E I+++P +G+ ++C VG AE VI WNL T E + K + G VS L T + L + +GY G+++V+D ++ E + + + +S I +L+C + D+ I ++D+ G +++GH+ IT+L +I VL+SS+QD IK W L CF TLT S +WDF LLV+G++++ LR+WRL + ++ S P + ++ N + T +P G V R +RV + D TG +LV + + +E++++L + KRL+KK KKA + + +V + SD L + + LP + A++SV + E L L ++ NN+I + + + ++ + + + IS GHRT + C LTSD L +FT++ +EA LW++ S T W + D+ K +L L+ +AS+ +L PGDRH +IGF++G
Sbjct: 1 MKVTKTYQDYHQDVVFGIIASEQPKINYVPASEGS--AVCAVGSAESVIFWNLVTSEAAAVFKRVSGI--GAVSCLCVTRGTQEKSLKLGVGYADGWVAVFDANSGESESNFRAGRSRVSAIEITEEKLVCAA-DSEIHVLDIVSGSGARMKGHRGIITRLKFIRNGKVLLSSAQDSFIKMWDLKNHHCFATLTGHSGPVWDFALSSDEQLLVSGAADSQLRVWRLFHSTHEECEVASAPVANLLE----NPTEDTIIPLSEHRSLISVEFLGVVQRNGTRRVHTLGFDATGTFLVVQSFARCVEIFQLLDQEAQTKRLRKKTKKARERGSSTEDVKLEMSDILLPVLRVSLPAKVASCAVNSVFSFWKNGILCEQRLRFLCALKNNSIEELEATFPAAGPLKPRTVSVTRSTVNGGTYVRLLNQISGPGHRTIPMACALTSDGLGVFTLARTEAKLWSRRSGHCLITLDWKLESPNHKKQMEDDPKNEADDLMLT-----KASSFILAPGDRHVVIGFESG 508 HSP 2 Score: 185.267 bits (469), Expect = 4.596e-95 Identity = 144/468 (30.77%), Postives = 227/468 (48.50%), Query Frame = 1
Query: 1549 DLVVESVLQYVK-RHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGT------------------------EADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGA----PRDTGINVLTIKTMNTERNADKLMEAIDIYDK--------IQIDPTAPIDPLMSGKGFTDAGRFVLHTISTI---------SGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA 2811
D+ ++V Q +K H ++ L LT D++ ++S G+DK + +N + + + + +L LV E + I+ +AV+P+ +L ++G ++ V Y D+ +RV LYGH+ PVT + + DS ++TGS DK+VR W L G+C + F H EP+T +IP S+A SCD +G+I Q D+ + E+ L+GH V+ LS V+ E + EL + S D S+R W ES+++L+ E ++ + E EE+ R VI GA +TG+ L T NT AD LMEA+DIYD+ Q P PLM +G RF+L T++ + G LE L + +A+ LL LAD ++KG +V L R + L LHF +V L + + + L ++G N+A
Sbjct: 514 DISSKAVRQTIKDAHNGAVRGLSLTGDKKGIVSGGSDKQVAFYNFD-----LNMPETGPPALCLVEARPKETAADQITCLAVSPNNRLLVLGLVNFHVDVYFA-DSFKRVHSLYGHAAPVTCLDISTDSRLIITGSGDKTVRLWELQFGNCQRRFTTHMEPITGACFIPHTSLAVSCDMAGIIKQWDVSKLREVTTLKGHEGPVTGLSAVSTNVTFVARQKTDKRPKKGKRNIEDDEEEDEFGELCGGVIASCGRDFSVRIWTESEELLILEEQEQLARE-AAEDEELVRSEAVIPGAVPAEASETGL--LGRPTPNTRDAADMLMEAMDIYDQEITKQHQAAQGKLVVPPHPLMLVRGTDSPERFLLSTLTALRAPTTRLGGGGAGLEHALGAITTEHARRLLPRLADWLSKGWEVELVGRAIRHLVTLHFGLIVNSADLRDVLHRSREARLNRLSEVKSLVGTNLA 972
BLAST of WD repeat-containing protein 3 vs. TrEMBL
Match: A0A0X3P1S5 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR151065 PE=4 SV=1) HSP 1 Score: 188.348 bits (477), Expect = 1.155e-93 Identity = 143/467 (30.62%), Postives = 225/467 (48.18%), Query Frame = 1
Query: 1549 DLVVESVLQYV-KRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVA----MG----------------TEADGDELENAE---------------LVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVG--APRDTGINVLTIKTMNTERNADKLMEAIDIYDKIQIDPTAPIDPLMSGKGFTDAGRFVLHTISTI------SGL-DLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA 2811
DL+ + Q + H ++ +L+LT D++ VLS G+D+ + WN +++ + +L L E + ++++A PD +L +G ++ V + D+ +RV LYG + PVT + + DS L+TGS DK+VR W L G+C + F H++PVT V+++ G S+AFS D G+I + D+ + E+ + GH +VS LS +A +G ++ ++E LVSV D S R W ES+++LV E E + + E+ E+ R VI G AP L T+ T AD LMEA+DIY K DP AP DPLM+ +D RF+ S++ GL LE L L + LL LA+ +G + L R ++L LH V L A++ + + +L +IG N+A
Sbjct: 539 DLLSKQATQTICDSHNSALRSLILTGDRKGVLSGGSDQRVGFWNFDFA-----LVPGGSPTLCLKPGRPVETVADQVTALAAAPDNRLIAVGMVNFHVDVFFA-DSFKRVHSLYGMAAPVTCMDISADSRLLITGSGDKTVRLWELQFGNCLRRFTTHSDPVTSVRFLAGSSLAFSADLGGIIKEWDVKKLLEVCTITGHEGAVSCLSALATKPGLGKLTRQQQQKTNKRGALSQKRRKQMEEGADEEDVDVDEDICGGLLVSVGRDFSCRVWRESEELLVMEEEALMAREAAEEEAELLRAEAVIPGAVAPEAAETGPLGRPTVTTRNAADTLMEAVDIYTKQISDPAAPPDPLMAAYQTSDPDRFLFTVFSSLRLPAMGGGLAGLEHSLGMLHSDHVVRLLPCLAEWFKRGWDLELVGRAIRYLCSLHAGLVTTSTELCDALSAIQTARRSHLSETRKLIGVNLA 999 HSP 2 Score: 187.578 bits (475), Expect = 1.155e-93 Identity = 150/539 (27.83%), Postives = 258/539 (47.87%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLG---TQEIVKTLHGKMDDKVSYLSYTHSDIFGLH-ISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNTHQLICGSKDTTISIIDVGDERGFKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFK--------KIDSDPFESTVQEQYSNAIQATPVP-----------GEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXXXXXXX-XDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAH----------LELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXX-------XXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGW--TWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNGVM 1540
+ I Y K+ D + G++ ++ + +L + G G C+ G D+ +WN+ + ++ +G VS L+ + + I++GY G++++Y + +L + + +H ++ I + + C + ++ + ++DV G++L+GH+ +T + ++++ +L+S +D IKFW L + CF TLT +W R LVTGSS+ LRLW+L++K K +SD + + N +A P+P G + R++ KRV + D G +L L+K LE+Y +LTEAE RL+KK KKA + A+ ++VC+TA D L+ + + L + + RK H L +L S NN + +++ IS A L + IS GHR+A CQLT D L IFT++ SE LWN++ T W + + +D + L ++ L+ASA +L PG RH ++GF+NGV+
Sbjct: 1 MPITHTYQKYTPDGVCGIVANDSVPVKYLNDAGGRNGVNCVSGCGSDIAVWNIRGSFKESLISRENGS--KPVSALAVSVDPVTSEPLIAVGYIDGWVALYSLWNQKLEYTFRAGRHRVNSIDFSGCTISCAA-ESELHVMDVLSGAGYRLKGHRGAVTIVKILNQQQILLSGGRDSFIKFWCLRTQHCFLTLTGHPGPVWGLALSADRKTLVTGSSDHLLRLWKLNYKTERLSSAGKSESDLLNAPRPLEKQNVSEAIPLPDYDSLVQVEFRGTIQRKTMKRVFSLTFDRGGRFLACQTLDKTLEIYILLTEAEKASRLRKKQKKARQKGDAEASSVCLTAEDELRCIFRLTLSAKLSSCDLRVSRFNSRKRPHDTKTLPPFALLHILCSYRNNLVEEYSLKISDPLPSKATLLHTSKVFHTDPDVAAAPTPLRLANRISNPGHRSAPFGCQLTEDGLGIFTLARSEGKLWNRTDLACLVTLDWGAVGSLSKKSSASDEWDDARGSTRLQAD-KLKASAFVLAPGSRHVVVGFENGVI 535
BLAST of WD repeat-containing protein 3 vs. Ensembl Cavefish
Match: wdr3 (WD repeat domain 3 [Source:NCBI gene;Acc:103032606]) HSP 1 Score: 152.525 bits (384), Expect = 4.658e-75 Identity = 136/525 (25.90%), Postives = 241/525 (45.90%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNT--HQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDF----KKI---------------DSDPFESTVQEQYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXX---------XXXXXXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++ +FGVIG + +NI+++ R G G VG E V IW++ E V L G D +YL + G+HI++GYE G + ++ + E VS HK +++ I ++ +L+ GS+DT + + DV +E G ++L+GHK IT+ ++ +++L++SS+D +K+W L + CFKT+ E+W + N L+TGS+++ LR W +++ K++ ++D + E I + G V RE RVV + D + + ++ LEL+ V+ E +++ R + K ++ ADP V +D L+ L I+ + + V P + K A L + NNTI + + + T + T R +++ GHRT +SDN+A+ + S +WN+++ + T + A +L +PGDR ++G K+G
Sbjct: 1 MGLTKQYLRYNASAVFGVIGSQKANIAYVTLRGGEKGRYVAVGACEHVFIWDVRKAEKVLILQGSKHD-ATYLCPSPD---GVHIAVGYEDGCVRIFSLLNGENNVSFNGHKSAVTSIQYDALGARLVTGSRDTDVIVWDVINECGLYRLKGHKDAITQALFLKDRNLLVTSSKDSFVKWWDLDTQHCFKTMVGHRSEVWGMVLLNQENRLLTGSADSELRGWDIEYLEEGKEVGEPMEKKGKSLLDDDEADSGDEGPNEDPEERILSCKKAGSVIREGRDRVVSLTADPKAKVVACHGVDGYLELFSVVPEEDVQKKIEKKLKKARKKAKSQEGGGEAADPV-VERKLTDELEKLTNIKASSKIRSVDCILFPNGELKVALL-----LQNNTIETYNLNTTEKNA--------------TGTKTSRLTLA--GHRTDARTLAFSSDNIAVLSASGDTVKVWNRATLQVIRTMACEY----------------------------ALCSLFVPGDRQIILGTKSG 471 HSP 2 Score: 150.599 bits (379), Expect = 4.658e-75 Identity = 117/447 (26.17%), Postives = 207/447 (46.31%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEY-------SSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIY----DKIQID-----------PTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIAHFK 2820
DL S+L+ + H ++ ++ L+ DQR +++ GADK + W+ E + +T+ H+ L + V +PD +L + +D V+ + T DT + L LYGH +PV + + +DS+ + TGS+D++V+ W L GDC + H + V ++++P + F+ K I Q D I L GH V L++ G +VS S D+S+R W +++ ++ E E+ E + +E+ E V+ G + KT+ T + A+++MEA+++Y K++ P +P++ G R+VL I + +LE+ L LP Y LL++ V +G +V L RC FL ++HF + + L+ I + ++ DV+GFN A +
Sbjct: 477 DLASGSLLETREAHDGALWSVCLSPDQRGIVTGGADKTVKFWDFELIKDKDSGPNKRLTLKHTRMLQLD-----------EDVLCVRYSPDQRLLAVSLLDCTVKIFYT-DTLKFFLSLYGHKLPVLCLDISHDSALIATGSADRNVKVWGLDFGDCHRSMFAHDDSVMFLQFVPKTHLFFTAGKDRKIKQWDADKFEHIQTLEGHKGEVWCLAISPSGD----------YVVSSSHDKSLRLWERTREPIILEEEKEMEREAEFEESLGKGEEPVVPGETKGEA-EPAGKKTIETVKAAERIMEALELYREESKKLEEHKAACEAAGKQLPPPKTNPILVAFGNISPSRYVLDVIKKVRSSELEVSLLVLPFPYIPDLLSLFNSYVQQGLEVELVCRCLFFLLRIHFGQITSNHMLLSVIDDLRTNTISKVREIRDVLGFNSAGLQ 900 HSP 3 Score: 52.7582 bits (125), Expect = 2.066e-6 Identity = 46/191 (24.08%), Postives = 81/191 (42.41%), Query Frame = 1
Query: 1765 KNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIFR--GHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEE 2331
K+ + + +PDG +G+ D VR + + V GH VTSI ++L+TGS D V W++ + +C ++R GH + +T ++ R++ + K + DL + GH V + ++ EN L++ S D +R W ++E +EE E E
Sbjct: 66 KHDATYLCPSPDGVHIAVGYEDGCVRIFSLLNGENNV-SFNGHKSAVTSIQYDALGARLVTGSRDTDVIVWDVIN-ECGLYRLKGHKDAITQALFLKDRNLLVTSSKDSFVKWWDLDTQHCFKTMVGHRSEVWGMVLLNQ---------EN-RLLTGSADSELRGW---------DIEYLEEGKEVGEPME 235
BLAST of WD repeat-containing protein 3 vs. Ensembl Cavefish
Match: wdr3 (WD repeat domain 3 [Source:NCBI gene;Acc:103032606]) HSP 1 Score: 152.525 bits (384), Expect = 4.658e-75 Identity = 136/525 (25.90%), Postives = 241/525 (45.90%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNT--HQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDF----KKI---------------DSDPFESTVQEQYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXX---------XXXXXXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++ +FGVIG + +NI+++ R G G VG E V IW++ E V L G D +YL + G+HI++GYE G + ++ + E VS HK +++ I ++ +L+ GS+DT + + DV +E G ++L+GHK IT+ ++ +++L++SS+D +K+W L + CFKT+ E+W + N L+TGS+++ LR W +++ K++ ++D + E I + G V RE RVV + D + + ++ LEL+ V+ E +++ R + K ++ ADP V +D L+ L I+ + + V P + K A L + NNTI + + + T + T R +++ GHRT +SDN+A+ + S +WN+++ + T + A +L +PGDR ++G K+G
Sbjct: 1 MGLTKQYLRYNASAVFGVIGSQKANIAYVTLRGGEKGRYVAVGACEHVFIWDVRKAEKVLILQGSKHD-ATYLCPSPD---GVHIAVGYEDGCVRIFSLLNGENNVSFNGHKSAVTSIQYDALGARLVTGSRDTDVIVWDVINECGLYRLKGHKDAITQALFLKDRNLLVTSSKDSFVKWWDLDTQHCFKTMVGHRSEVWGMVLLNQENRLLTGSADSELRGWDIEYLEEGKEVGEPMEKKGKSLLDDDEADSGDEGPNEDPEERILSCKKAGSVIREGRDRVVSLTADPKAKVVACHGVDGYLELFSVVPEEDVQKKIEKKLKKARKKAKSQEGGGEAADPV-VERKLTDELEKLTNIKASSKIRSVDCILFPNGELKVALL-----LQNNTIETYNLNTTEKNA--------------TGTKTSRLTLA--GHRTDARTLAFSSDNIAVLSASGDTVKVWNRATLQVIRTMACEY----------------------------ALCSLFVPGDRQIILGTKSG 471 HSP 2 Score: 150.599 bits (379), Expect = 4.658e-75 Identity = 117/447 (26.17%), Postives = 207/447 (46.31%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEY-------SSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIY----DKIQID-----------PTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIAHFK 2820
DL S+L+ + H ++ ++ L+ DQR +++ GADK + W+ E + +T+ H+ L + V +PD +L + +D V+ + T DT + L LYGH +PV + + +DS+ + TGS+D++V+ W L GDC + H + V ++++P + F+ K I Q D I L GH V L++ G +VS S D+S+R W +++ ++ E E+ E + +E+ E V+ G + KT+ T + A+++MEA+++Y K++ P +P++ G R+VL I + +LE+ L LP Y LL++ V +G +V L RC FL ++HF + + L+ I + ++ DV+GFN A +
Sbjct: 477 DLASGSLLETREAHDGALWSVCLSPDQRGIVTGGADKTVKFWDFELIKDKDSGPNKRLTLKHTRMLQLD-----------EDVLCVRYSPDQRLLAVSLLDCTVKIFYT-DTLKFFLSLYGHKLPVLCLDISHDSALIATGSADRNVKVWGLDFGDCHRSMFAHDDSVMFLQFVPKTHLFFTAGKDRKIKQWDADKFEHIQTLEGHKGEVWCLAISPSGD----------YVVSSSHDKSLRLWERTREPIILEEEKEMEREAEFEESLGKGEEPVVPGETKGEA-EPAGKKTIETVKAAERIMEALELYREESKKLEEHKAACEAAGKQLPPPKTNPILVAFGNISPSRYVLDVIKKVRSSELEVSLLVLPFPYIPDLLSLFNSYVQQGLEVELVCRCLFFLLRIHFGQITSNHMLLSVIDDLRTNTISKVREIRDVLGFNSAGLQ 900 HSP 3 Score: 52.7582 bits (125), Expect = 2.066e-6 Identity = 46/191 (24.08%), Postives = 81/191 (42.41%), Query Frame = 1
Query: 1765 KNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIFR--GHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEE 2331
K+ + + +PDG +G+ D VR + + V GH VTSI ++L+TGS D V W++ + +C ++R GH + +T ++ R++ + K + DL + GH V + ++ EN L++ S D +R W ++E +EE E E
Sbjct: 66 KHDATYLCPSPDGVHIAVGYEDGCVRIFSLLNGENNV-SFNGHKSAVTSIQYDALGARLVTGSRDTDVIVWDVIN-ECGLYRLKGHKDAITQALFLKDRNLLVTSSKDSFVKWWDLDTQHCFKTMVGHRSEVWGMVLLNQ---------EN-RLLTGSADSELRGW---------DIEYLEEGKEVGEPME 235
BLAST of WD repeat-containing protein 3 vs. Ensembl Cavefish
Match: wdr3 (WD repeat domain 3 [Source:NCBI gene;Acc:103032606]) HSP 1 Score: 152.91 bits (385), Expect = 8.365e-74 Identity = 139/525 (26.48%), Postives = 242/525 (46.10%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNT--HQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDF------------KK----IDSDPFESTVQ---EQYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXX---------XXXXXXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++ +FGVIG + +NI+++ R G G VG E V IW++ E V L G D +YL + G+HI++GYE G + ++ + E VS HK +++ I ++ +L+ GS+DT + + DV +E G ++L+GHK IT+ ++ +++L++SS+D +K+W L + CFKT+ E+W + N L+TGS+++ LR W +++ KK +D D +S + E I + G V RE RVV + D + + ++ LEL+ V+ E +++ R + K ++ ADP V +D L+ L I+ + + V P + K A L + NNTI + + + T + T R +++ GHRT +SDN+A+ + S +WN+++ + T + A +L +PGDR ++G K+G
Sbjct: 1 MGLTKQYLRYNASAVFGVIGSQKANIAYVTLRGGEKGRYVAVGACEHVFIWDVRKAEKVLILQGSKHD-ATYLCPSPD---GVHIAVGYEDGCVRIFSLLNGENNVSFNGHKSAVTSIQYDALGARLVTGSRDTDVIVWDVINECGLYRLKGHKDAITQALFLKDRNLLVTSSKDSFVKWWDLDTQHCFKTMVGHRSEVWGMVLLNQENRLLTGSADSELRGWDIEYLEEGKEVGEPMEKKGKSLLDDDEADSGDEGPNEDPEERILSCKKAGSVIREGRDRVVSLTADPKAKVVACHGVDGYLELFSVVPEEDVQKKIEKKLKKARKKAKSQEGGGEAADPV-VERKLTDELEKLTNIKASSKIRSVDCILFPNGELKVALL-----LQNNTIETYNLNTTEKNA--------------TGTKTSRLTLA--GHRTDARTLAFSSDNIAVLSASGDTVKVWNRATLQVIRTMACEY----------------------------ALCSLFVPGDRQIILGTKSG 471 HSP 2 Score: 145.976 bits (367), Expect = 8.365e-74 Identity = 117/426 (27.46%), Postives = 201/426 (47.18%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIY----DKIQIDPTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA 2811
DL S+L+ + H ++ ++ L+ DQR +++ GADK + W+ E I S N + + V +PD +L + +D V+ + T DT + L LYGH +PV + + +DS+ + TGS+D++V+ W L GDC + H + V ++++P + F+ K I Q D I L GH V L++ G +VS S D+S+R W +++ ++ E E+ E + +E+ E V+ G + KT+ T + A+++MEA+++Y K++ A +GK R+VL I + +LE+ L LP Y LL++ V +G +V L RC FL ++HF + + L+ I + ++ DV+GFN A
Sbjct: 477 DLASGSLLETREAHDGALWSVCLSPDQRGIVTGGADKTVKFWDFEL----IKDKDSGPNKRLTLKHTRMLQLDEDVLCVRYSPDQRLLAVSLLDCTVKIFYT-DTLKFFLSLYGHKLPVLCLDISHDSALIATGSADRNVKVWGLDFGDCHRSMFAHDDSVMFLQFVPKTHLFFTAGKDRKIKQWDADKFEHIQTLEGHKGEVWCLAISPSGD----------YVVSSSHDKSLRLWERTREPIILEEEKEMEREAEFEESLGKGEEPVVPGETKGEA-EPAGKKTIETVKAAERIMEALELYREESKKLEEHKAA---CEAAGK---QPSRYVLDVIKKVRSSELEVSLLVLPFPYIPDLLSLFNSYVQQGLEVELVCRCLFFLLRIHFGQITSNHMLLSVIDDLRTNTISKVREIRDVLGFNSA 880 HSP 3 Score: 52.7582 bits (125), Expect = 2.238e-6 Identity = 46/191 (24.08%), Postives = 81/191 (42.41%), Query Frame = 1
Query: 1765 KNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIFR--GHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEE 2331
K+ + + +PDG +G+ D VR + + V GH VTSI ++L+TGS D V W++ + +C ++R GH + +T ++ R++ + K + DL + GH V + ++ EN L++ S D +R W ++E +EE E E
Sbjct: 66 KHDATYLCPSPDGVHIAVGYEDGCVRIFSLLNGENNV-SFNGHKSAVTSIQYDALGARLVTGSRDTDVIVWDVIN-ECGLYRLKGHKDAITQALFLKDRNLLVTSSKDSFVKWWDLDTQHCFKTMVGHRSEVWGMVLLNQ---------EN-RLLTGSADSELRGW---------DIEYLEEGKEVGEPME 235
BLAST of WD repeat-containing protein 3 vs. Ensembl Cavefish
Match: wdr3 (WD repeat domain 3 [Source:NCBI gene;Acc:103032606]) HSP 1 Score: 143.28 bits (360), Expect = 8.111e-67 Identity = 132/516 (25.58%), Postives = 235/516 (45.54%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNT--HQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDF----KKI---------------DSDPFESTVQEQYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
+G+ K YL++ +FGVIG + +NI+++ R G G VG E V IW++ E V L G D +YL + G+HI++GYE G + ++ + E VS HK +++ I ++ +L+ GS+DT + + DV +E G ++L+GHK IT+ ++ +++L++SS+D +K+W L + CFKT+ E+W + N L+TGS+++ LR W +++ K++ ++D + E I + G V RE RVV + D + + ++ LEL+ V+ E +++K+++KKLKKA K + I P L++ + + NNTI + + + T + T R +++ GHRT +SDN+A+ + S +WN+++ + T + A +L +PGDR ++G K+G
Sbjct: 1 MGLTKQYLRYNASAVFGVIGSQKANIAYVTLRGGEKGRYVAVGACEHVFIWDVRKAEKVLILQGSKHD-ATYLCPSPD---GVHIAVGYEDGCVRIFSLLNGENNVSFNGHKSAVTSIQYDALGARLVTGSRDTDVIVWDVINECGLYRLKGHKDAITQALFLKDRNLLVTSSKDSFVKWWDLDTQHCFKTMVGHRSEVWGMVLLNQENRLLTGSADSELRGWDIEYLEEGKEVGEPMEKKGKSLLDDDEADSGDEGPNEDPEERILSCKKAGSVIREGRDRVVSLTADPKAKVVACHGVDGYLELFSVVPEEDVQKKIEKKLKKARKKAKS--------------VDCILFP-----------------NGELKVALLLQNNTIETYNLNTTEKNA--------------TGTKTSRLTLA--GHRTDARTLAFSSDNIAVLSASGDTVKVWNRATLQVIRTMACEY----------------------------ALCSLFVPGDRQIILGTKSG 437 HSP 2 Score: 132.494 bits (332), Expect = 8.111e-67 Identity = 114/434 (26.27%), Postives = 200/434 (46.08%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIY---DKIQIDPTAPIDPLMSGKGFTDAGRFVLHTI---------STISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIA 2811
DL S+L+ + H ++ ++ L+ DQR +++ GADK + W+ E I S N + + V +PD +L + +D V+ + T DT + L LYGH +PV + + +DS+ + TGS+D++V+ W L GDC + H + V ++++P + F+ K I Q D I L GH V L++ G +VS S D+S+R W +++ ++ E E+ E + +E+ E V+ G + KT+ T + A+++MEA+++Y K + A + +GK + ++ I ++S L + L LP Y LL++ V +G +V L RC FL ++HF + + L+ I + ++ DV+GFN A
Sbjct: 443 DLASGSLLETREAHDGALWSVCLSPDQRGIVTGGADKTVKFWDFEL----IKDKDSGPNKRLTLKHTRMLQLDEDVLCVRYSPDQRLLAVSLLDCTVKIFYT-DTLKFFLSLYGHKLPVLCLDISHDSALIATGSADRNVKVWGLDFGDCHRSMFAHDDSVMFLQFVPKTHLFFTAGKDRKIKQWDADKFEHIQTLEGHKGEVWCLAISPSGD----------YVVSSSHDKSLRLWERTREPIILEEEKEMEREAEFEESLGKGEEPVVPGETKGEA-EPAGKKTIETVKAAERIMEALELYREESKKLEEHKAACEA--AGKQVWNIFSYLSINIYCYCLEQIYKSLSNLWNSVSLLVLPFPYIPDLLSLFNSYVQQGLEVELVCRCLFFLLRIHFGQITSNHMLLSVIDDLRTNTISKVREIRDVLGFNSA 858 HSP 3 Score: 53.1434 bits (126), Expect = 1.693e-6 Identity = 44/191 (23.04%), Postives = 80/191 (41.88%), Query Frame = 1
Query: 1765 KNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIFR--GHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEE 2331
K+ + + +PDG +G+ D VR + + V GH VTSI ++L+TGS D V W++ + +C ++R GH + +T ++ R++ + K + DL + GH V + ++ + L++ S D +R W ++E +EE E E
Sbjct: 66 KHDATYLCPSPDGVHIAVGYEDGCVRIFSLLNGENNV-SFNGHKSAVTSIQYDALGARLVTGSRDTDVIVWDVIN-ECGLYRLKGHKDAITQALFLKDRNLLVTSSKDSFVKWWDLDTQHCFKTMVGHRSEVWGMVLLN----------QENRLLTGSADSELRGW---------DIEYLEEGKEVGEPME 235
BLAST of WD repeat-containing protein 3 vs. Ensembl Cavefish
Match: wdr3 (WD repeat domain 3 [Source:NCBI gene;Acc:103032606]) HSP 1 Score: 150.984 bits (380), Expect = 6.962e-58 Identity = 117/447 (26.17%), Postives = 207/447 (46.31%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEY-------SSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIY----DKIQID-----------PTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIAHFK 2820
DL S+L+ + H ++ ++ L+ DQR +++ GADK + W+ E + +T+ H+ L + V +PD +L + +D V+ + T DT + L LYGH +PV + + +DS+ + TGS+D++V+ W L GDC + H + V ++++P + F+ K I Q D I L GH V L++ G +VS S D+S+R W +++ ++ E E+ E + +E+ E V+ G + KT+ T + A+++MEA+++Y K++ P +P++ G R+VL I + +LE+ L LP Y LL++ V +G +V L RC FL ++HF + + L+ I + ++ DV+GFN A +
Sbjct: 407 DLASGSLLETREAHDGALWSVCLSPDQRGIVTGGADKTVKFWDFELIKDKDSGPNKRLTLKHTRMLQLD-----------EDVLCVRYSPDQRLLAVSLLDCTVKIFYT-DTLKFFLSLYGHKLPVLCLDISHDSALIATGSADRNVKVWGLDFGDCHRSMFAHDDSVMFLQFVPKTHLFFTAGKDRKIKQWDADKFEHIQTLEGHKGEVWCLAISPSGD----------YVVSSSHDKSLRLWERTREPIILEEEKEMEREAEFEESLGKGEEPVVPGETKGEA-EPAGKKTIETVKAAERIMEALELYREESKKLEEHKAACEAAGKQLPPPKTNPILVAFGNISPSRYVLDVIKKVRSSELEVSLLVLPFPYIPDLLSLFNSYVQQGLEVELVCRCLFFLLRIHFGQITSNHMLLSVIDDLRTNTISKVREIRDVLGFNSAGLQ 830 HSP 2 Score: 94.7449 bits (234), Expect = 6.962e-58 Identity = 105/453 (23.18%), Postives = 188/453 (41.50%), Query Frame = 2
Query: 266 SYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNTHQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDFFYCDTRNLLVTGSSETTLRLWRLDF----KKI---------------DSDPFESTVQEQYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXX---------XXXXXXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNG 1534
YL Y S +FG+ IG + I+ + E + +I KDT + + DV +E G ++L+GHK IT+ ++ +++L++SS+D +K+W L + CFKT+ E+W + N L+TGS+++ LR W +++ K++ ++D + E I + G V RE RVV + D + + ++ LEL+ V+ E +++ R + K ++ ADP V +D L+ L I+ + + V P + K A L + NNTI + + + T + T R +++ GHRT +SDN+A+ + S +WN+++ + T + A +L +PGDR ++G K+G
Sbjct: 6 QYLRYNASAVFGV---IGSQKANIAYVTLRGGEKGRYVAVGACEHVFIWDVRK----AEKDTDVIVWDVINECGLYRLKGHKDAITQALFLKDRNLLVTSSKDSFVKWWDLDTQHCFKTMVGHRSEVWGMVLLNQENRLLTGSADSELRGWDIEYLEEGKEVGEPMEKKGKSLLDDDEADSGDEGPNEDPEERILSCKKAGSVIREGRDRVVSLTADPKAKVVACHGVDGYLELFSVVPEEDVQKKIEKKLKKARKKAKSQEGGGEAADPV-VERKLTDELEKLTNIKASSKIRSVDCILFPNGELKVALL-----LQNNTIETYNLNTTEKNA--------------TGTKTSRLTLA--GHRTDARTLAFSSDNIAVLSASGDTVKVWNRATLQVIRTMACEY----------------------------ALCSLFVPGDRQIILGTKSG 401
BLAST of WD repeat-containing protein 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000993.1 (pep scaffold:Pmarinus_7.0:GL491095:506:6076:1 gene:ENSPMAG00000000901.1 transcript:ENSPMAT00000000993.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 91.2781 bits (225), Expect = 7.347e-21 Identity = 70/232 (30.17%), Postives = 123/232 (53.02%), Query Frame = 2
Query: 56 LGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYT-----HSD----IFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILH--NTHQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTT-SIEIWDF--FYCDTRNLLVTGSSETTLR 706
+G+ K YL++A +FG++ +N +F+ R G V E V++W+L E V + G + V+ L+ H G+ ++ G+ G + + + T E V+ H+ +I+ + + + +L+ GS+DT + + DV E G ++L+GHK +T + S K+VL++ S+D +KFW L + CFKTL ++W F DTR LVTGS+++ L+
Sbjct: 1 MGLTKQYLRYAPGPVFGLVASARANAAFVALR-GERARFAAVATCELVVVWDLRKGEKVLIIPGDKSE-VTRLAAAPCRGRHGGEEGYAAGVELAAGHVDGAVRLLSLITGEKRVTFTGHRTAITALAYHPDGTRLVSGSQDTDVIVWDVVGECGLYRLKGHKDAVTSARFFSTKNVLLTGSKDSFVKFWDLDTQHCFKTLVGHRSDVWSLATFGEDTR--LVTGSADSELQ 228
BLAST of WD repeat-containing protein 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002506.1 (pep scaffold:Pmarinus_7.0:GL479076:26529:32136:-1 gene:ENSPMAG00000002224.1 transcript:ENSPMAT00000002506.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 68.1662 bits (165), Expect = 2.115e-12 Identity = 60/213 (28.17%), Postives = 99/213 (46.48%), Query Frame = 1
Query: 1579 VKRHTESISALVLT-QDQRCVLSAGADKCLLMWNIEYSSTAITIA----HSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTY-LTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIF---RGHTEPVTDVKYIPGRS--MAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGT 2184
+K H ++ + T Q +LSA DK L+MW + T I H HG+ +S V ++ DG+ + G D +R + LTT T+ R GH+ V S++ D+ Q+++GS DK+++ WN G CK GHTE V+ V++ P + + SC L+ +L N GH +++++V G+
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTLIMWKLTRDETNYGIPQRSLHGHGH---------------FVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR--RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTL-GVCKYTIQEDGHTEWVSCVRFSPNNNNPIIVSCGWDKLVKVWNLTNCKLKTNHIGHTGYLNTVTVSPDGS 205
BLAST of WD repeat-containing protein 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008900.1 (pep scaffold:Pmarinus_7.0:GL476968:456285:462943:1 gene:ENSPMAG00000008058.1 transcript:ENSPMAT00000008900.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 62.3882 bits (150), Expect = 1.024e-10 Identity = 62/244 (25.41%), Postives = 117/244 (47.95%), Query Frame = 1
Query: 2134 RGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIY----DKIQID-----------PTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIAHFK 2820
+GH V S++V GD + +S + D+S+R W +++ LV E E+ E + YE+ +A+ IV + + KTM T + A+++MEA+++Y K++ P +DP++ G ++VL I + +LE L LP +Y LL + + +GR V L R FL ++H + + L+ I+++ + + + ++ D++GFN+A +
Sbjct: 1 QGHHGEVWSVAV-----SPSGDHI-----LSAAHDKSLRLWERTREPLVLEDEREMEREAEYEES-VAKGAEPIVPGETEGEAGMAARKTMETVKAAERIMEALELYRVESQKLEEHKQACKAANKQLPPPVLDPVLVASGSVTPEKYVLEVIKKVKSSELEEALLVLPFSYVPELLALFLLFLRQGRAVELICRALFFLLRIHHGQITSNGMLLEVISELRESSLLRVREMRDLVGFNMAALQ 233
BLAST of WD repeat-containing protein 3 vs. Ensembl Sea Lamprey
Match: wdr48a (WD repeat domain 48a [Source:ZFIN;Acc:ZDB-GENE-061110-55]) HSP 1 Score: 63.929 bits (154), Expect = 1.291e-10 Identity = 46/179 (25.70%), Postives = 91/179 (50.84%), Query Frame = 1
Query: 1579 VKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHN 2112
++ H + + AL +D+ V SAG D+ + +W++ + TA+T +++ + SL K++I S+A+ G + + G + +R + T +++ L GH+ V ++ + D +Q L+GSSD ++R W+L C +R H E V ++ + +S + + DL N
Sbjct: 113 LRTHKDYVKALAYAKDKEQVASAGLDRQIFLWDVN-TLTALTASNNTVTTSSLSGN------KDSIYSLAMNQMGTIIVSGSTEKVLRVW-DPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDTFTQVYSGGRDRKVYCTDLRN 283
BLAST of WD repeat-containing protein 3 vs. Ensembl Sea Lamprey
Match: wdr48a (WD repeat domain 48a [Source:ZFIN;Acc:ZDB-GENE-061110-55]) HSP 1 Score: 63.929 bits (154), Expect = 1.326e-10 Identity = 46/179 (25.70%), Postives = 91/179 (50.84%), Query Frame = 1
Query: 1579 VKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHN 2112
++ H + + AL +D+ V SAG D+ + +W++ + TA+T +++ + SL K++I S+A+ G + + G + +R + T +++ L GH+ V ++ + D +Q L+GSSD ++R W+L C +R H E V ++ + +S + + DL N
Sbjct: 113 LRTHKDYVKALAYAKDKEQVASAGLDRQIFLWDVN-TLTALTASNNTVTTSSLSGN------KDSIYSLAMNQMGTIIVSGSTEKVLRVW-DPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDTFTQVYSGGRDRKVYCTDLRN 283
BLAST of WD repeat-containing protein 3 vs. Ensembl Yeast
Match: DIP2 (Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex [Source:SGD;Acc:S000004119]) HSP 1 Score: 117.087 bits (292), Expect = 3.937e-27 Identity = 112/466 (24.03%), Postives = 209/466 (44.85%), Query Frame = 1
Query: 1549 DLVVESVLQYVK-RHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEK------EEMARERIVIVGAPRD------TGINVLTIKTMNTERNADKLMEAID-----------------IYDKIQIDPTAPIDPLMSGKGFTDA-----GRFVLHTISTISGLDLELILSQLPVTYA----KLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVV--RDPTLVPAITKMAKYAKIYLQRNVDVIGFNIAHFK 2820
DL S+L ++ H +I +L LT D + +++ ADK + W+ + ++ + + + + +T + I V V+PD + I +D+ V+ + D+ + L LYGH +PV SI + +DS ++T S+DK+++ W L GDC K H + + +VK++P FSC K ++ D I +L H V +L+V G +VS S D SIR W E++D + E E+ +E + YE EE + A + +G++ T++++ + ++LMEA+D ++ + ++ API P G A ++++ T+ I LE L +P +Y K + ++ ++ + L + F+ K + +V ++ L I ++ + L+ D +GFN+ K
Sbjct: 458 DLASSSLLDTIEDAHDAAIWSLDLTSDGKRLVTGSADKTVKFWDFKVENSLVPGTKNKFLPVLKLHHDTTLELTDDILCVRVSPDDRYLAISLLDNTVKVFFL-DSMKFYLSLYGHKLPVLSIDISFDSKMIITSSADKNIKIWGLDFGDCHKSLFAHQDSIMNVKFLPQSHNFFSCSKDAVVKYWDGEKFECIQKLYAHQSEVWALAVATDG----------GFVVSSSHDHSIRIWEETEDQVFLEEEKEKELEEQYEDTLLTSLEEGNGDDAFKADASGEGVEDEASGVHKQTLESL---KAGERLMEALDLGIAEIEGLEAYNRDMKLWQRKKLGE-APIKP--QGNAVLIAVNKTPEQYIMDTLLRIRMSQLEDALMVMPFSYVLKFLKFIDTVMQNKTLLHSHLPLICKNLFFIIKFNHKELVSQKNEELKLQINRVKTELRSALKSTEDDLGFNVQGLK 906 HSP 2 Score: 92.8189 bits (229), Expect = 1.185e-19 Identity = 113/459 (24.62%), Postives = 210/459 (45.75%), Query Frame = 2
Query: 62 IVKNYLKFAHDTLFGVIGCENSNISFLP----NRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTL-----------HGKMDDKVSYL-SYTHSDIFGLHISIGYESGYISVYDV--STYELXXXXXXXXXXXXYILHNTHQLICGSKDTTISIIDVGDERG-FKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKT-LTTSIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKKIDSDPFESTVQEQYSNAIQATPVPGEVNRESPKRVVEMKI-----DETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXXXXXXXXDPANVCITASDR-----LKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWN 1348
+VK+Y +F FGVI N+N ++P N +G+ + EDV IW++ T ++V L G + +YL ++ +D+ +++GY G I V+D+ T L + ++ +LI GSKD+ I + D+ E G +KL HK IT + +D LIS+S+DG IK W L +C +T + + E W D +LL+T +++ +++W+LD I++D + E G ++S +R ++++ D+T + + NA +K +E +R+ E E+ + L+K+ K+ + + + + L + I Y+ K + +V +K LEL+++ +NTI +++ PA + T ++ ++ G RT + ++ DN + T S +WN
Sbjct: 1 MVKSYQRFEQAAAFGVIAS-NANCVWIPASSGNSNGSGPGQLITSALEDVNIWDIKTGDLVSKLSDGLPPGASDARGAKPAECTYLEAHKDTDL----LAVGYADGVIKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDLVGEVGLYKLRSHKDSITGF-WCQGEDWLISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAVKD--DLLITTGTDSQVKIWKLD---IENDKMGGKLTEM-----------GIFEKQSKQRGLKIEFITNSSDKTSFFYIQNA-DKTIETFRIRKEEEIARGLKKREKRLKEKGLTEEEIAKSIKESYSSFILHPFQTIRSLYKIKSASWTTVSSSK-----LELVLTTSSNTIEYYSIPYEK-------RDPTSPAPLKTHTIELQ------GQRTDVRSIDISDDNKLLATASNGSLKIWN 418
BLAST of WD repeat-containing protein 3 vs. Ensembl Yeast
Match: TAF5 (Subunit (90 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification [Source:SGD;Acc:S000000402]) HSP 1 Score: 69.707 bits (169), Expect = 1.293e-12 Identity = 53/226 (23.45%), Postives = 97/226 (42.92%), Query Frame = 1
Query: 1588 HTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITI-AHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQ-SVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
H+ ++ + + D + +LS DK + +W+++ + ++ H+H + V+ +P G F D R + + D + GH V +S + + TGSSDK+ R W++ GD ++F GHT PV + P + + G+I D+ + ++RGHG+ ++ SLS G L+S D ++R W
Sbjct: 524 HSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNH-----------------PVWDVSFSPLGHYFATASHDQTARLW-SCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGN----------VLISGGADHTVRVW 721 HSP 2 Score: 50.447 bits (119), Expect = 1.217e-6 Identity = 53/199 (26.63%), Postives = 80/199 (40.20%), Query Frame = 1
Query: 1726 SLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTY----------------LTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNL-PHGDCKIFRGHTEPVTDVKYIP-GRSMA-FSCDKSGLIIQIDLHNMSEIIRLR---GHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
+L VC T + +S + + D ++ GF DS ++ + D L GHS V S S D+ LL+GS DK+VR W++ H ++GH PV DV + P G A S D++ + D I LR GH V +S G + + S+D++ R W
Sbjct: 453 ALPSVCMYTFQNTNKDMSCLDFSDDCRIAAAGFQDSYIKIWSLDGSSLNNPNIALNNNDKDEDPTCKTLVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWSCD-----HIYPLRIFAGHLNDVDCVSFHPNG----------CYVFTGSSDKTCRMW 636
BLAST of WD repeat-containing protein 3 vs. Ensembl Yeast
Match: TUP1 (General repressor of transcription; forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes [Source:SGD;Acc:S000000680]) HSP 1 Score: 56.9954 bits (136), Expect = 1.196e-8 Identity = 50/173 (28.90%), Postives = 76/173 (43.93%), Query Frame = 1
Query: 1774 ISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIFRGHTEPVTDVKYIPGRS---MAFSCDK--------SGLIIQ-IDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
I SV +PDGK G D +R + + + V+ L GH + S+ +L++GS D++VR W+L G C + + VT V PG A S D+ +G +++ +D N S GH SV S+ G +VS S DRS++ W
Sbjct: 446 IRSVCFSPDGKFLATGAEDRLIRIW-DIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDLRTGQCSLTLSIEDGVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGT----GHKDSVYSVVFTRDG----------QSVVSGSLDRSVKLW 603 HSP 2 Score: 51.9878 bits (123), Expect = 4.242e-7 Identity = 59/259 (22.78%), Postives = 109/259 (42.08%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTP-DGKLFIIGFMDSKVRTYLTTDTSRRVLDL-------YGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPH------------GDCKI-FRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDEL--ENAELVSVSTDRSIRFW 2256
D+ ++ ++ H + I +L ++S D+ + +W++ ++T++ ++ +++VAV+P DGK G +D VR + ++T V L GH V S+ D +++GS D+SV+ WNL + G C++ + GH + V V S K ++ D + + ++ L+GH SV S++V A+G L E + S D R W
Sbjct: 471 DIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDLRTGQCSLTLS-----------------IEDGVTTVAVSPGDGKYIAAGSLDRAVRVW-DSETGFLVERLDSENESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDEYILSGSKDRGVLFWDKKSGNPLLMLQGHRNSVISVAV------ANGSPLGPEYNVFATGSGDCKARIW 705
BLAST of WD repeat-containing protein 3 vs. Ensembl Yeast
Match: MET30 (F-box protein containing five copies of the WD40 motif; controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus; dissociation of Met30p from SCF complex in response to cadmium stress is regulated by Cdc48p [Source:SGD;Acc:S000001308]) HSP 1 Score: 55.4546 bits (132), Expect = 3.033e-8 Identity = 47/161 (29.19%), Postives = 73/161 (45.34%), Query Frame = 1
Query: 1798 DGKLFIIGFMDSKVR--TYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQ--LLTGSSDKSVRSWNLPHGDCKIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGH-GQ-------SVSSLSVVAMGTEADGDELENAELVSVSTDRS 2244
D + I G +D +R Y+T + + GHS V S+ DS Q +++GS+DK+V+ W++ C RGHTE V VK P FSC I D+ S + RGH GQ ++ + +A +DG ++ ++ D S
Sbjct: 351 DDRKLITGSLDKTIRVWNYITGEC---ISTYRGHSDSVLSV----DSYQKVIVSGSADKTVKVWHVESRTCYTLRGHTEWVNCVKLHPKSFSCFSCSDDTTIRMWDIRTNSCLKVFRGHVGQVQKIIPLTIKDVENLATDNTSDGSSPQDDPTMTDGADES 504 HSP 2 Score: 49.2914 bits (116), Expect = 2.944e-6 Identity = 41/152 (26.97%), Postives = 70/152 (46.05%), Query Frame = 1
Query: 1804 KLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
+L G DS + + T + + L GHS V ++ +D +L+TGS DK++R WN G+C +RGH++ V V ++ S DK+ + ++ LRGH + V+ + + ++ S S D +IR W
Sbjct: 313 RLLFTGSYDSTIGIW-DLFTGKLIRRLSGHSDGVKTLY--FDDRKLITGSLDKTIRVWNYITGECISTYRGHSDSVLSVDSYQKVIVSGSADKTVKVWHVESRT---CYTLRGHTEWVNCVKL----------HPKSFSCFSCSDDTTIRMW 448
BLAST of WD repeat-containing protein 3 vs. Ensembl Yeast
Match: MDV1 (Peripheral protein of cytosolic face of mitochondrial outer membrane; required for mitochondrial fission; interacts with Fis1p and with the self-assembled oligomeric form of the dynamin-related GTPase Dnm1p; contains WD repeats; MDV1 has a paralog, CAF4, that arose from the whole genome duplication [Source:SGD;Acc:S000003648]) HSP 1 Score: 53.1434 bits (126), Expect = 1.703e-7 Identity = 45/174 (25.86%), Postives = 77/174 (44.25%), Query Frame = 1
Query: 1540 APVDLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLS-----------LVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIFRGHTEPV 2028
+P + + + + HT+ ++AL L D ++S D+ + W++ TI S N L+ L+ Q P A+ S G D VR + + + + L GH+ +TS+ K+DS+ L+TGS D++VR W+L G F ++ PV
Sbjct: 485 SPTNHIDSPCVHTFEAHTDEVTALSL--DPSFLVSGSQDRTIRQWDLRSGKCLQTIDLSFANVLTTSTNVDLSKSTLLTQRNERPSIGALQSFDAA-----LATGTKDGVVRLW-DLRSGKVIRTLKGHTDAITSL--KFDSACLVTGSYDRTVRIWDLRTGLLNKFHAYSAPV 648
BLAST of WD repeat-containing protein 3 vs. Ensembl Nematostella
Match: EDO49767 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFR6]) HSP 1 Score: 70.0922 bits (170), Expect = 6.679e-13 Identity = 63/259 (24.32%), Postives = 112/259 (43.24%), Query Frame = 1
Query: 1567 VLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIE----------------------YSSTAITIAHSHG------NSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLP-HGDCKIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
+L+ + + +I + +T D + +++ GAD + +W+ E ++ ++ A H ++LSLV T + KN +S V VTPD K I D V+ + +T V L GH V I++ D +L++ S D+++R WNL RGH+E V V P A S + ++ DL + E+ L GH + +++V G ++++S D ++ W
Sbjct: 5 LLRTIDGRSRTILGIAVTPDTKKIITGGADGSIRVWDYETGKELNKLLDHTKLVYTLALSPHADFLVSGAFDHTVKIWDMDTLSLV--HTLKGHKNWVSGVLVTPDSKRIISSSYDKTVKIW-DVETCAFVNSLDGHDGHVRGIAITSDGRRLVSASQDRTLRIWNLETFAHVSTLRGHSETVYCVCCSPDDKFAISGSEDTMVKIWDLESAKEVRSLVGHTSDIFAVAVTPDG----------SKVISSGDDTQVKVW 250 HSP 2 Score: 58.5362 bits (140), Expect = 3.489e-9 Identity = 41/155 (26.45%), Postives = 75/155 (48.39%), Query Frame = 1
Query: 1588 HTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHG-DCKIFRGHTEPVTDVKYIP 2049
H + + +T D R ++SA D+ L +WN+E + T+ G+S ++ C V +PD K I G D+ V+ + ++++ V L GH+ + +++V D S++++ D V+ W+L G + GH+E V V P
Sbjct: 138 HDGHVRGIAITSDGRRLVSASQDRTLRIWNLETFAHVSTL---RGHSETVYC-------------VCCSPDDKFAISGSEDTMVKIW-DLESAKEVRSLVGHTSDIFAVAVTPDGSKVISSGDDTQVKVWSLESGEELASLHGHSESVRIVTVSP 275
BLAST of WD repeat-containing protein 3 vs. Ensembl Nematostella
Match: EDO34865 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN68]) HSP 1 Score: 67.3958 bits (163), Expect = 1.113e-11 Identity = 56/228 (24.56%), Postives = 97/228 (42.54%), Query Frame = 1
Query: 1582 KRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKY-IPGRSMA-FSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
+ H+ I L + + D +W+++ T I+ G+S ++ S A G + G D V + T + RRV L GH +++ +D S ++TGS DK+ + W+ G C RGH + V DV + G+ +A S D +G + H+ + +L GH +S ++ A GT L++ S+D++ R W
Sbjct: 174 RGHSAEIVCLAFNPQSTVIATGSMDTTAKLWDVQ---TGAEISTLSGHSAEII-------------SCAFNSTGTQLLTGSFDHTVSVW-DTRSGRRVHTLIGHRGEISNAQFNFDCSFIVTGSMDKTCKIWDAGTGKCIGTLRGHDDEVLDVAFDYTGQLIATASADGTGRVYNALTHHC--LSKLEGHEGEISKITFNAQGT----------RLLTASSDKTARLW 372
BLAST of WD repeat-containing protein 3 vs. Ensembl Nematostella
Match: EDO41779 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3I9]) HSP 1 Score: 65.855 bits (159), Expect = 6.796e-11 Identity = 73/313 (23.32%), Postives = 127/313 (40.58%), Query Frame = 1
Query: 1570 LQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMAR-----ERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIYDKIQIDPTAPID 2490
+ ++ H + + AL + V S G DK + +W++ + TA+T ++ + SL Q K++I S+A+ P G + I G + +R + + +V+ L GH V ++ + D Q L+GSSD +VR W+L C ++R H E V + + FS + I D+ L G V L +N L +T+ I W I E D Y E ++R R+ I GA ++L + ++ D + DI +++ +D
Sbjct: 111 MSTLRTHKDYVQALAYASCKEHVASGGLDKQIFLWDVN-TLTALTATNNTVTTSSLSGQ------KDSIYSLAMNPAGTVLISGSTEKILRVW-DPRSCEKVMKLKGHMDNVKAVVIDSDGQQCLSGSSDGTVRLWSLGQQRCVAVYRIHEEGVWALLANDNFTEFFSSGRDKHIFWTDMRRDDSSALLFTEGAPVLRLESCP----------DNTSLWVATTNSRINNW----PIKFPSYENHSAGDLGY-NESVSRPLCTTPRMTIQGASSIKKFHILKDRRHVLTKDTDNCVALFDILKARKVEDLGQVD 400
BLAST of WD repeat-containing protein 3 vs. Ensembl Nematostella
Match: EDO34676 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNL4]) HSP 1 Score: 64.3142 bits (155), Expect = 1.258e-10 Identity = 43/173 (24.86%), Postives = 81/173 (46.82%), Query Frame = 1
Query: 1522 IQERSHAPVDLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPH-GDCKIFRGHTEPVTDV 2037
+Q + + L ++ ++ H + ++ L ++ D + V +A D ++ WN++ IA G L + + K I ++A+T DGK G D +R + DTS+ + GH ++ ++ + S QL + S DK+V+ WNL + GH + VT +
Sbjct: 118 VQRKIADQLSLSSTHTIRILRGHQQPVTCLCVSPDDKFVFTAAKDCTIIKWNVDSGKREFRIAG--GPKL----EAGSKGHKEQILALAITTDGKYLASGGKDKLIRIW-DPDTSKHIHTFKGHRDVISGLAFRRGSHQLFSASHDKTVKIWNLDEMAYVETLFGHQDAVTGI 283
BLAST of WD repeat-containing protein 3 vs. Ensembl Nematostella
Match: EDO33060 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST98]) HSP 1 Score: 60.8474 bits (146), Expect = 1.784e-9 Identity = 52/196 (26.53%), Postives = 85/196 (43.37%), Query Frame = 1
Query: 1771 AISSVAVTPDGKLFIIGFMDSKVRTYLTT---------------------DTSRRVLD---------LYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKI-FRGHTEPVTDVKYIPGRSMAF---SCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
++ ++ D L GF DS +R + T D R++D L GHS PV ++S+ +D+ LL+ S DK++R W+L + +RGH PV DV++ P R F S D++ + D I GH VS ++V+A + + + S+DR++R W
Sbjct: 276 GVNCATISEDAALLSAGFEDSTIRIWTLTPRKLRMLKPPSELNKIDKEAEDVMERIMDDRTASESRRLVGHSGPVFAVSIDHDNKFLLSCSEDKTIRLWSLFTFTTLVAYRGHNYPVWDVQFCP-RGHYFASTSHDRTARLWSTDHQQPLRI--FAGH---VSDVNVIAFHPNCN-------YIATGSSDRTVRLW 458 HSP 2 Score: 57.7658 bits (138), Expect = 1.873e-8 Identity = 55/228 (24.12%), Postives = 94/228 (41.23%), Query Frame = 1
Query: 1588 HTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYI-PGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYES 2265
H+ + A+ + D + +LS DK + +W++ ++ T + H + V P G F D R + +TD + + GH V I+ + + + TGSSD++VR W++ G ++F GH V + + GR + S + L++ DL + + L+GH +V SL GT L S D I+ W S
Sbjct: 346 HSGPVFAVSIDHDNKFLLSCSEDKTIRLWSL-FTFTTLVAYRGHNY---------------PVWDVQFCPRGHYFASTSHDRTARLW-STDHQQPLRIFAGHVSDVNVIAFHPNCNYIATGSSDRTVRLWDIQTGSSVRLFTGHKAAVQSLAFSRNGRHLISSGVDTRLLVW-DLAEGTLVAELKGHTDTVYSLCFSRDGT----------ILASAGLDNCIKLWNTS 545
BLAST of WD repeat-containing protein 3 vs. Ensembl Medaka
Match: rack1 (receptor for activated C kinase 1 [Source:NCBI gene;Acc:101162055]) HSP 1 Score: 67.781 bits (164), Expect = 4.082e-12 Identity = 64/234 (27.35%), Postives = 109/234 (46.58%), Query Frame = 1
Query: 1579 VKRHTESISALVLT-QDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTY-LTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIF---RGHTEPVTDVKYIPGRS--MAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTE-ADGDELENAELVSVSTDRSIRFW 2256
+K H+ ++ + T Q +LSA DK ++MW + T I Q + + + +S V ++ DG+ + G D +R + LTT + R GH+ V S++ D+ Q+++GS DK+++ WN G CK GHTE V+ V++ P S + SC ++ +L N GH +++++V G+ A G + L + TD IR W
Sbjct: 11 LKGHSGWVTQIATTPQYPDMILSASRDKSIIMWKLTRDETNYGIP-----------QRSLKGHSHFVSDVVISSDGQFALSGAWDGTLRLWDLTTGLTTR--QFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTL-GVCKYTIQDEGHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGK----TLFAGYTDNLIRVW 226
BLAST of WD repeat-containing protein 3 vs. Ensembl Medaka
Match: taf5 (TATA-box binding protein associated factor 5 [Source:NCBI gene;Acc:101175542]) HSP 1 Score: 67.3958 bits (163), Expect = 5.375e-11 Identity = 52/224 (23.21%), Postives = 95/224 (42.41%), Query Frame = 1
Query: 1588 HTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
H+ + + + D+ +LS D + +W++ L+ C + + +P G F+ G D R + TD + + GH VT +S+ ++TGSSD+++R W++ G+C +IF GH P+ + + P S G ++ D+ + + L+GH +V +L DG+ L S S D ++R W
Sbjct: 490 HSGPVYGISFSPDRNYLLSCSEDGTVRLWSL----------------LTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLW-ATDHYQPLRIFAGHLADVTCTRFHPNSNYVVTGSSDRTIRLWDVLTGNCVRIFTGHKGPIHTLAFSPNGKFLASGATDGRVLLWDIGHGLMVSELKGHTDTVYALRF-----SRDGE-----ILASGSMDNTVRLW 686 HSP 2 Score: 55.8398 bits (133), Expect = 1.938e-7 Identity = 42/139 (30.22%), Postives = 59/139 (42.45%), Query Frame = 1
Query: 1726 SLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTT---------------------DTSRRVLD---------LYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKI-FRGHTEPVTDVKYIP 2049
+L +C T +++V T D L GF DS VR + T D R++D LYGHS PV IS D + LL+ S D +VR W+L C + ++GH PV D ++ P
Sbjct: 405 NLPSICFYTFLNAYQGLTAVDFTDDSSLIAGGFADSTVRVWSVTPKKLRKVKSAADLNLIDKESDDVLERIMDEKTASESKILYGHSGPVYGISFSPDRNYLLSCSEDGTVRLWSLLTFTCLVGYKGHNYPVWDTQFSP 543
BLAST of WD repeat-containing protein 3 vs. Ensembl Medaka
Match: rack1 (receptor for activated C kinase 1 [Source:NCBI gene;Acc:101162055]) HSP 1 Score: 65.855 bits (159), Expect = 5.660e-11 Identity = 56/209 (26.79%), Postives = 99/209 (47.37%), Query Frame = 1
Query: 1579 VKRHTESISALVLT-QDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTY-LTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIF---RGHTEPVTDVKYIPGRS--MAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGT 2184
+K H+ ++ + T Q +LSA DK ++MW + T I Q + + + +S V ++ DG+ + G D +R + LTT + R GH+ V S++ D+ Q+++GS DK+++ WN G CK GHTE V+ V++ P S + SC ++ +L N GH +++++V G+
Sbjct: 11 LKGHSGWVTQIATTPQYPDMILSASRDKSIIMWKLTRDETNYGIP-----------QRSLKGHSHFVSDVVISSDGQFALSGAWDGTLRLWDLTTGLTTR--QFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWN-TLGVCKYTIQDEGHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGS 205
BLAST of WD repeat-containing protein 3 vs. Ensembl Medaka
Match: wdr48b (WD repeat domain 48 [Source:NCBI gene;Acc:101162785]) HSP 1 Score: 66.2402 bits (160), Expect = 1.093e-10 Identity = 48/182 (26.37%), Postives = 92/182 (50.55%), Query Frame = 1
Query: 1570 LQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHN 2112
+ ++ H + + AL +D+ V SAG D+ + +W++ + TA+T +++ + SL K++I S+A+ G + + G + +R + T +++ L GH+ V S+ + D +Q L+GSSD ++R W+L C +R H E V ++ + +S + I DL N
Sbjct: 110 MSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN-TLTALTASNNTVTTSSLSGN------KDSIYSLAMNQMGTVIVSGSTEKVLRVW-DPRTCAKLMKLKGHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNEAFTHVYSGGRDKKIYCTDLRN 283
BLAST of WD repeat-containing protein 3 vs. Ensembl Medaka
Match: ENSORLT00000010396.2 (pep primary_assembly:ASM223467v1:21:1602549:1605935:-1 gene:ENSORLG00000008284.2 transcript:ENSORLT00000010396.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 58.5362 bits (140), Expect = 3.942e-9 Identity = 39/141 (27.66%), Postives = 68/141 (48.23%), Query Frame = 1
Query: 2398 KTMNTERNADKLMEAIDIYDKIQIDPTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIAHFK 2820
KT+ T + A+++MEA++++ + ++ G G R+VL I + +LE+ L LP Y LL + + + +G +V L RC FL K+HF + + L+ I + + DV+GFN A +
Sbjct: 33 KTVETVKAAERIMEALELHRE-ELRKMEEHKYACEGAG-KQPARYVLDVIKAVRSSELEVSLLVLPFPYVPELLQLFSSYIHQGLEVELVCRCLFFLLKIHFGQITSNQMLLSVIDDLHSVTVSKVCEIRDVMGFNSAALQ 171
BLAST of WD repeat-containing protein 3 vs. Planmine SMEST
Match: SMESG000002152.1 (SMESG000002152.1) HSP 1 Score: 924.465 bits (2388), Expect = 0.000e+0 Identity = 494/498 (99.20%), Postives = 498/498 (100.00%), Query Frame = 2
Query: 47 MTKLGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELXXXXXXXXXXXXYILHNTHQLICGSKDTTISIIDVGDERGFKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTTSIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKKIDSDPFESTVQEQYSNAIQATPVPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAEXXXXXXXXXXXXXXXXXDPANVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMHNNTIAVFTVGISSDXXXXXXXXXXXXXXIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNGVM 1540
MTKLGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELVVSSKIHKHSISYILHNTHQLICGSKDTTISIIDVGDERGFKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTTSIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKKIDSDPFESTVQEQYSNAIQATP+PGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAELKKRLQKKLKKAAKTKADPA+VCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSM+NNTIAVFTVGISSDA+PAVAGAAPRPAAIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNGVM
Sbjct: 1 MTKLGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDVIIWNLGTQEIVKTLHGKMDDKVSYLSYTHSDIFGLHISIGYESGYISVYDVSTYELVVSSKIHKHSISYILHNTHQLICGSKDTTISIIDVGDERGFKLEGHKSPITKLHYISKKDVLISSSQDGEIKFWFLSLKRCFKTLTTSIEIWDFFYCDTRNLLVTGSSETTLRLWRLDFKKIDSDPFESTVQEQYSNAIQATPIPGEVNRESPKRVVEMKIDETGNYLVSNALEKRLELYRVLTEAELKKRLQKKLKKAAKTKADPADVCITASDRLKLLKVIELPYRCKRVAIHSVPETKRKEAHLELLVSMYNNTIAVFTVGISSDAVPAVAGAAPRPAAIDTKSLTMRASISQCGHRTAIIHCQLTSDNLAIFTVSLSEAILWNKSSTRFRSTAGWTWDYVRDNDDADNFKRIFTELGLSSNTHLEASAALLLPGDRHALIGFKNGVM 498 HSP 2 Score: 913.679 bits (2360), Expect = 0.000e+0 Identity = 441/443 (99.55%), Postives = 441/443 (99.55%), Query Frame = 1
Query: 1549 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIYDKIQIDPTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKIYLQRNVDVIGFNIAHFKRHMKLMGPELLTFTEQRSV 2877
DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAIT AHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIYDKIQIDPTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAK YLQRNVDVIGFNIAHFKRHMKLMGPELLTFTEQRSV
Sbjct: 502 DLVVESVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITTAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVEQMEENDRCYEKEEMARERIVIVGAPRDTGINVLTIKTMNTERNADKLMEAIDIYDKIQIDPTAPIDPLMSGKGFTDAGRFVLHTISTISGLDLELILSQLPVTYAKLLLNILADQVAKGRQVGLANRCYQFLAKLHFMAVVRDPTLVPAITKMAKYAKFYLQRNVDVIGFNIAHFKRHMKLMGPELLTFTEQRSV 944
BLAST of WD repeat-containing protein 3 vs. Planmine SMEST
Match: SMESG000008519.1 (SMESG000008519.1) HSP 1 Score: 60.4622 bits (145), Expect = 2.039e-9 Identity = 55/246 (22.36%), Postives = 101/246 (41.06%), Query Frame = 1
Query: 1564 SVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIFR--GHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSE-IIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVE 2292
S+ K HT + + V + G D ++W++E + +++ G++ ++ + + +GK I G D V + RRV L GH +++ +D + + T S DKS++ W+L G +F GHT+ V DV + S + D+ + S+ +GH VS ++ GT L+S S D+S R W + +++ +E
Sbjct: 46 SLYHTFKGHTAEVVCVQFNPSSTLVGTGGMDTLAMLWDVE---SGKCVSNLQGHTAEVISLQFGQA-----------HNGKHLITGSFDHTVILW-DVHNGRRVSQLIGHDAEISAAVFNFDGTYVATASMDKSIKIWDLRMGARDLFTLAGHTDEVLDVTFDNVGKQVASAGADNTVRLWDVKDFSKPSFIFKGHEAEVSKVTFNPQGT----------VLLSASADKSARTWNTTTGKVIQVLE 266 HSP 2 Score: 53.1434 bits (126), Expect = 4.323e-7 Identity = 35/130 (26.92%), Postives = 58/130 (44.62%), Query Frame = 1
Query: 1588 HTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSW 1977
HT+ + + + V SAGAD + +W+++ S I H + +S V P G + + D RT+ TT T + + L GH+ + S + YD S+++TGS D + R W
Sbjct: 183 HTDEVLDVTFDNVGKQVASAGADNTVRLWDVKDFSKPSFIFKGH---------------EAEVSKVTFNPQGTVLLSASADKSARTWNTT-TGKVIQVLEGHTDEIFSCAFNYDGSKIITGSKDNTCRIW 296
BLAST of WD repeat-containing protein 3 vs. Planmine SMEST
Match: SMESG000024482.1 (SMESG000024482.1) HSP 1 Score: 56.9954 bits (136), Expect = 5.538e-8 Identity = 51/228 (22.37%), Postives = 89/228 (39.04%), Query Frame = 1
Query: 1576 YVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKI-FRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
+ K H + ++ + + + S G D CL++WN + + A V E +AI SV +P G+L D VR ++ + ++ H+ V S+ + D+ +++TGS DK+++ W + H V V++ + S I D HN I + HG V SL+ G+ + S TD + W
Sbjct: 9 HFKGHKDKVTCVDFNPNSSQLASGGIDSCLMIWNFKPQTRA----------YRFVGHE------DAILSVKFSPTGQLVASASRDKTVRLWVPSIKGESLV-FRAHTATVRSVDISCDNLEMVTGSDDKTIKVWKMHRQKFSYSLNEHKNWVRCVRFSSDGQLIASSSDDKTIKLWDRHNQECIHTFQEHGGFVPSLAFHPNGS----------YIASGGTDSHVNIW 209
BLAST of WD repeat-containing protein 3 vs. Planmine SMEST
Match: SMESG000008519.1 (SMESG000008519.1) HSP 1 Score: 54.6842 bits (130), Expect = 7.542e-8 Identity = 45/168 (26.79%), Postives = 73/168 (43.45%), Query Frame = 1
Query: 1798 DGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIFR--GHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSE-IIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFWYESQDILVREVE 2292
+GK I G D V + RRV L GH +++ +D + + T S DKS++ W+L G +F GHT+ V DV + S + D+ + S+ +GH VS ++ GT L+S S D+S R W + +++ +E
Sbjct: 36 NGKHLITGSFDHTVILW-DVHNGRRVSQLIGHDAEISAAVFNFDGTYVATASMDKSIKIWDLRMGARDLFTLAGHTDEVLDVTFDNVGKQVASAGADNTVRLWDVKDFSKPSFIFKGHEAEVSKVTFNPQGT----------VLLSASADKSARTWNTTTGKVIQVLE 192 HSP 2 Score: 53.5286 bits (127), Expect = 1.500e-7 Identity = 35/130 (26.92%), Postives = 58/130 (44.62%), Query Frame = 1
Query: 1588 HTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSW 1977
HT+ + + + V SAGAD + +W+++ S I H + +S V P G + + D RT+ TT T + + L GH+ + S + YD S+++TGS D + R W
Sbjct: 109 HTDEVLDVTFDNVGKQVASAGADNTVRLWDVKDFSKPSFIFKGH---------------EAEVSKVTFNPQGTVLLSASADKSARTWNTT-TGKVIQVLEGHTDEIFSCAFNYDGSKIITGSKDNTCRIW 222
BLAST of WD repeat-containing protein 3 vs. Planmine SMEST
Match: SMESG000008529.1 (SMESG000008529.1) HSP 1 Score: 55.4546 bits (132), Expect = 1.194e-7 Identity = 48/205 (23.41%), Postives = 86/205 (41.95%), Query Frame = 1
Query: 1564 SVLQYVKRHTESISALVLTQDQRCVLSAGADKCLLMWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYDSSQLLTGSSDKSVRSWNLPHGDCKIFR--GHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSE-IIRLRGHGQSVSSLSV 2169
S+ K HT + + V + G D ++W++E + +++ G++ ++ + F A +GK I G D V + RRV L GH +++ +D + + T S DKS++ W+L G +F GHT+ V DV + S + D+ + S+ +GH VS +S+
Sbjct: 168 SLYHTFKGHTAEVVCVQFNPSSTLVGTGGMDTLAMLWDVE---SGKCVSNLQGHTAEVISLQ----FGQA-------HNGKHLITGSFDHTVILW-DVHNGRRVSQLIGHDAEISAAVFNFDGTYVATASMDKSIKIWDLRMGARDLFTLAGHTDEVLDVTFDNVGKQVASAGADNTVRLWDVKDFSKPSFIFKGHEAEVSKVSI 357 HSP 2 Score: 50.0618 bits (118), Expect = 5.421e-6 Identity = 40/163 (24.54%), Postives = 70/163 (42.94%), Query Frame = 1
Query: 1774 ISSVAVTPDGKLFIIGFMDSKVRTYLTTDTSRRVLDLYGHSMPVTSISVKYD-SSQLLTGSSDKSVRSWNLPHGDC-KIFRGHTEPVTDVKYIPGRSMAFSCDKSGLIIQIDLHNMSEIIRLRGHGQSVSSLSVVAMGTEADGDELENAELVSVSTDRSIRFW 2256
+++V +G F+ G D + + T + L GH V SI+ S +++TGS DK+ + W+ G F+GHT V V++ P ++ + L + D+ + + L+GH V SL G L++ S D ++ W
Sbjct: 95 LTNVTFNKNGDRFLTGSYDRTCKVW-DTSMGTTLFTLEGHKNVVYSIAYNLPFSDKIVTGSFDKTAKMWSANDGSLYHTFKGHTAEVVCVQFNPSSTLVGTGGMDTLAMLWDVESGKCVSNLQGHTAEVISLQF--------GQAHNGKHLITGSFDHTVILW 248 The following BLAST results are available for this feature:
BLAST of WD repeat-containing protein 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of WD repeat-containing protein 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of WD repeat-containing protein 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of WD repeat-containing protein 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of WD repeat-containing protein 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of WD repeat-containing protein 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of WD repeat-containing protein 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of WD repeat-containing protein 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of WD repeat-containing protein 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of WD repeat-containing protein 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of WD repeat-containing protein 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of WD repeat-containing protein 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of WD repeat-containing protein 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of WD repeat-containing protein 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30003242 ID=SMED30003242|Name=WD repeat-containing protein 3|organism=Schmidtea mediterranea sexual|type=transcript|length=2926bpback to top protein sequence of SMED30003242-orf-1 >SMED30003242-orf-1 ID=SMED30003242-orf-1|Name=SMED30003242-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=512bp MTKLGIVKNYLKFAHDTLFGVIGCENSNISFLPNRDGNVGSLCMVGFAEDback to top protein sequence of SMED30003242-orf-2 >SMED30003242-orf-2 ID=SMED30003242-orf-2|Name=SMED30003242-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=413bp MWNIEYSSTAITIAHSHGNSLSLVCQETPEPFKNAISSVAVTPDGKLFIIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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