Choline-phosphate cytidylyltransferase B

Overview
NameCholine-phosphate cytidylyltransferase B
Smed IDSMED30003233
Length (bp)1148
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Choline-phosphate cytidylyltransferase B (SMED30003233) t-SNE clustered cells

Violin plots show distribution of expression levels for Choline-phosphate cytidylyltransferase B (SMED30003233) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Choline-phosphate cytidylyltransferase B (SMED30003233) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Choline-phosphate cytidylyltransferase B (SMED30003233) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30003233

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30003233SMESG000047766.1 Contig1692GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
nervous systemSMED30003233SMESG000047771.1 SMESG000047766.1 dd_Smed_v4_4008_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30003233SMESG000047771.1 SMESG000047766.1 dd_Smed_v4_4008_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30003233SMESG000047771.1 SMESG000047766.1 OX_Smed_1.0.19538ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
body wall musculatureSMED30003233SMESG000047771.1 SMESG000047766.1 dd_Smed_v4_4008_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Human
Match: PCYT1B (phosphate cytidylyltransferase 1, choline, beta [Source:HGNC Symbol;Acc:HGNC:8755])

HSP 1 Score: 276.174 bits (705), Expect = 2.973e-90
Identity = 138/291 (47.42%), Postives = 196/291 (67.35%), Query Frame = 1 
Query:  100 KMNQFSPAPFSNE-ECALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLFEK----TMLFRNKPIEPIDILTPASSPMES 924
            ++   +PAPF++E  C  +  ++     K+++ QA+ G  A R +RVYADG++D+FH+GHAR L+QAK  FPN YL+ GVC+D  T+  KG TVM E ERYEA+RHCRYVDEV+ DAPW+   +FLE+HKIDFVAHDDIPY +    DVYK +KE  MF+ TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK  +FQ +   +KEK K + + +K            +I KWE ++ +FI +F  LF        +F+ +    +  L+P  SP++S
Sbjct:   38 RLTLTAPAPFADETNCQCQAPHE-----KLTIAQARLGTPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPLKS 323
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Human
Match: PCYT1B (phosphate cytidylyltransferase 1, choline, beta [Source:HGNC Symbol;Acc:HGNC:8755])

HSP 1 Score: 273.478 bits (698), Expect = 6.791e-89
Identity = 137/284 (48.24%), Postives = 192/284 (67.61%), Query Frame = 1 
Query:  115 SPAPFSNE-ECALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLFEK----TMLFRNKPIEPIDILTPASSPM 918
            +PAPF++E  C  +  ++     K+++ QA+ G  A R +RVYADG++D+FH+GHAR L+QAK  FPN YL+ GVC+D  T+  KG TVM E ERYEA+RHCRYVDEV+ DAPW+   +FLE+HKIDFVAHDDIPY +    DVYK +KE  MF+ TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK  +FQ +   +KEK K + + +K            +I KWE ++ +FI +F  LF        +F+ +    +  L+P  SP+
Sbjct:   25 APAPFADETNCQCQAPHE-----KLTIAQARLGTPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPV 303
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Human
Match: PCYT1B (phosphate cytidylyltransferase 1, choline, beta [Source:HGNC Symbol;Acc:HGNC:8755])

HSP 1 Score: 274.248 bits (700), Expect = 7.431e-89
Identity = 137/289 (47.40%), Postives = 194/289 (67.13%), Query Frame = 1 
Query:  100 KMNQFSPAPFSNE-ECALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLFEK----TMLFRNKPIEPIDILTPASSPM 918
            ++   +PAPF++E  C  +  ++     K+++ QA+ G  A R +RVYADG++D+FH+GHAR L+QAK  FPN YL+ GVC+D  T+  KG TVM E ERYEA+RHCRYVDEV+ DAPW+   +FLE+HKIDFVAHDDIPY +    DVYK +KE  MF+ TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK  +FQ +   +KEK K + + +K            +I KWE ++ +FI +F  LF        +F+ +    +  L+P  SP+
Sbjct:   38 RLTLTAPAPFADETNCQCQAPHE-----KLTIAQARLGTPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPV 321
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Human
Match: PCYT1A (phosphate cytidylyltransferase 1, choline, alpha [Source:HGNC Symbol;Acc:HGNC:8754])

HSP 1 Score: 255.373 bits (651), Expect = 1.185e-82
Identity = 128/264 (48.48%), Postives = 180/264 (68.18%), Query Frame = 1 
Query:   97 CKMNQFSPAPFSNEECALKLLNDCNYS---IKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            C +    PAPFS+E        + ++S   +++++ +A  G    R +RVYADG++D+FH+GHAR L+QAKN FPN YLI GVC+D  T+  KG TVM E+ERY+AV+HCRYVDEV+ +APW+   +FL +H+IDFVAHDDIPY +    DVYK +KE  MF  TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK    QE+   +K+K K + + +K            +I KWE ++ +FI SF  +F
Sbjct:   37 CAVGLRQPAPFSDE-------IEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMF 293
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Human
Match: PCYT1A (phosphate cytidylyltransferase 1, choline, alpha [Source:HGNC Symbol;Acc:HGNC:8754])

HSP 1 Score: 256.529 bits (654), Expect = 5.125e-82
Identity = 128/264 (48.48%), Postives = 180/264 (68.18%), Query Frame = 1 
Query:   97 CKMNQFSPAPFSNEECALKLLNDCNYS---IKISLNQAKSGLA-PRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            C +    PAPFS+E        + ++S   +++++ +A  G    R +RVYADG++D+FH+GHAR L+QAKN FPN YLI GVC+D  T+  KG TVM E+ERY+AV+HCRYVDEV+ +APW+   +FL +H+IDFVAHDDIPY +    DVYK +KE  MF  TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK    QE+   +K+K K + + +K            +I KWE ++ +FI SF  +F
Sbjct:   37 CAVGLRQPAPFSDE-------IEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMF 293
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Celegans
Match: pcyt-1 (Putative choline-phosphate cytidylyltransferase [Source:UniProtKB/Swiss-Prot;Acc:P49583])

HSP 1 Score: 258.07 bits (658), Expect = 4.005e-83
Identity = 122/245 (49.80%), Postives = 165/245 (67.35%), Query Frame = 1 
Query:  118 PAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEK 852
            PAPFS+E  A+      +YS KI+L  A++  A R +R+YADG+YD+FH GHA QL Q K  FPN+YLI GVC D DT+  KG+TV +E+ERY+ VRHCRYVDEV  +APW   ++FL+  K+DF+AHD IPY A    D+Y+  + + MFL T+RTEGVST+DV+ RI++DYD Y+RRN+QRG S ++LN+ F+     Q Q K   LK KG          ++  W+S+++D IR F   F K
Sbjct:   45 PAPFSDEALAITTREAVDYSKKITLAMAEANEAGRPVRIYADGIYDLFHHGHANQLRQVKKMFPNVYLIVGVCGDRDTHKYKGRTVTSEEERYDGVRHCRYVDEVYREAPWFCTVEFLKNLKVDFIAHDAIPYVAPGEEDLYEKFRREGMFLETERTEGVSTSDVVCRIIRDYDKYVRRNLQRGYSPKELNVGFLAASKYQIQNKVDSLKSKGI--------ELLSTWKSKSDDIIRDFIDTFHK 281
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Celegans
Match: pcyt-1 (Putative choline-phosphate cytidylyltransferase [Source:UniProtKB/Swiss-Prot;Acc:P49583])

HSP 1 Score: 257.684 bits (657), Expect = 5.004e-83
Identity = 122/245 (49.80%), Postives = 165/245 (67.35%), Query Frame = 1 
Query:  118 PAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEK 852
            PAPFS+E  A+      +YS KI+L  A++  A R +R+YADG+YD+FH GHA QL Q K  FPN+YLI GVC D DT+  KG+TV +E+ERY+ VRHCRYVDEV  +APW   ++FL+  K+DF+AHD IPY A    D+Y+  + + MFL T+RTEGVST+DV+ RI++DYD Y+RRN+QRG S ++LN+ F+     Q Q K   LK KG          ++  W+S+++D IR F   F K
Sbjct:   37 PAPFSDEALAITTREAVDYSKKITLAMAEANEAGRPVRIYADGIYDLFHHGHANQLRQVKKMFPNVYLIVGVCGDRDTHKYKGRTVTSEEERYDGVRHCRYVDEVYREAPWFCTVEFLKNLKVDFIAHDAIPYVAPGEEDLYEKFRREGMFLETERTEGVSTSDVVCRIIRDYDKYVRRNLQRGYSPKELNVGFLAASKYQIQNKVDSLKSKGI--------ELLSTWKSKSDDIIRDFIDTFHK 273
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Celegans
Match: Y18H1A.11 (pep chromosome:WBcel235:I:680408:683472:1 gene:WBGene00021215.1 transcript:Y18H1A.11a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y18H1A.11)

HSP 1 Score: 247.284 bits (630), Expect = 4.526e-80
Identity = 117/244 (47.95%), Postives = 159/244 (65.16%), Query Frame = 1 
Query:  115 SPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLF 846
            SPAPFS++   +K     +YS +I+L  A SG   R +RVYADGVYDMFH GHA Q LQ K   PN+YLI GVC+D +T  NKG+TV  E+ERYEA+RHCRYVDEV   +PW+  + FL++ K+DF++HD +PY+     D+Y+  +   MFL TQRTEG+ST+D I RI++DYD+Y+RRN+QRG S  DLN+ F      + Q+    +KE G        R ++  W++ A+  I  F   F
Sbjct:   10 SPAPFSDDVEVIKQREAIDYSTQITLEDAISGNVTRPVRVYADGVYDMFHYGHANQFLQIKQTLPNVYLIVGVCSDEETMKNKGRTVQGEEERYEAIRHCRYVDEVYKASPWTCPIPFLKELKVDFMSHDALPYQGPAGEDIYEKHRTAGMFLETQRTEGISTSDSICRIIRDYDTYVRRNLQRGYSATDLNVGFFTTSKYRLQDTVVGIKEMG--------RGLLQTWKTNADYLIEGFLTTF 245
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Celegans
Match: Y18H1A.11 (pep chromosome:WBcel235:I:680408:683257:1 gene:WBGene00021215.1 transcript:Y18H1A.11b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y18H1A.11)

HSP 1 Score: 206.453 bits (524), Expect = 2.597e-65
Identity = 95/176 (53.98%), Postives = 126/176 (71.59%), Query Frame = 1 
Query:  115 SPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDS 642
            SPAPFS++   +K     +YS +I+L  A SG   R +RVYADGVYDMFH GHA Q LQ K   PN+YLI GVC+D +T  NKG+TV  E+ERYEA+RHCRYVDEV   +PW+  + FL++ K+DF++HD +PY+     D+Y+  +   MFL TQRTEG+ST+D I RI++DYD+
Sbjct:   10 SPAPFSDDVEVIKQREAIDYSTQITLEDAISGNVTRPVRVYADGVYDMFHYGHANQFLQIKQTLPNVYLIVGVCSDEETMKNKGRTVQGEEERYEAIRHCRYVDEVYKASPWTCPIPFLKELKVDFMSHDALPYQGPAGEDIYEKHRTAGMFLETQRTEGISTSDSICRIIRDYDT 185
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Celegans
Match: Y18H1A.11 (pep chromosome:WBcel235:I:680479:683472:1 gene:WBGene00021215.1 transcript:Y18H1A.11c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y18H1A.11)

HSP 1 Score: 202.986 bits (515), Expect = 1.364e-63
Identity = 93/197 (47.21%), Postives = 128/197 (64.97%), Query Frame = 1 
Query:  256 MFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLF 846
            MFH GHA Q LQ K   PN+YLI GVC+D +T  NKG+TV  E+ERYEA+RHCRYVDEV   +PW+  + FL++ K+DF++HD +PY+     D+Y+  +   MFL TQRTEG+ST+D I RI++DYD+Y+RRN+QRG S  DLN+ F      + Q+    +KE G        R ++  W++ A+  I  F   F
Sbjct:    1 MFHYGHANQFLQIKQTLPNVYLIVGVCSDEETMKNKGRTVQGEEERYEAIRHCRYVDEVYKASPWTCPIPFLKELKVDFMSHDALPYQGPAGEDIYEKHRTAGMFLETQRTEGISTSDSICRIIRDYDTYVRRNLQRGYSATDLNVGFFTTSKYRLQDTVVGIKEMG--------RGLLQTWKTNADYLIEGFLTTF 189
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Fly
Match: Pcyt2 (gene:FBgn0035231 transcript:FBtr0072742)

HSP 1 Score: 304.679 bits (779), Expect = 6.081e-101
Identity = 148/295 (50.17%), Postives = 201/295 (68.14%), Query Frame = 1 
Query:   46 PKIPS--LQSSVLSIYAYLCKMNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEKTML---FRNKPIEPIDILTPASSP 915
            P  P+  ++  +L ++      +   PAPFS ++ A+  L  C+Y+ +I+ + A++G   R++RVYADG+YD+FH GHARQL+QAKN FPN+YLI GVCND  T   KG+TVM   ERYEAVRHCRYVDE++ +APW+   +F+E+HKIDFVAHDDIPY AG V D+Y  LK K MF+AT+RTEGVST+D+++RIVKDYD Y+RRN+ RG S ++LN+SF+ EK  + Q K   LK +GK      K  II KWE ++ +FI +F  LF +  L   +       I  L+P  SP
Sbjct:   17 PATPTSPMEFKMLPLFMDFEDFSICQPAPFSYDDKAMLELERCDYTQRITYHMARAGKTTRRVRVYADGIYDLFHQGHARQLMQAKNVFPNVYLIVGVCNDELTLRMKGRTVMNGFERYEAVRHCRYVDEIVPNAPWTLNEEFIEEHKIDFVAHDDIPYGAGGVNDIYAPLKAKGMFVATERTEGVSTSDIVARIVKDYDVYVRRNLARGYSAKELNVSFLSEKKFRLQNKMDELKTRGKRELTKVKVDIITKWEEKSREFIDAFLLLFGRERLNTFWNESKGRIIQALSPPGSP 311
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Fly
Match: Pcyt1 (gene:FBgn0041342 transcript:FBtr0072741)

HSP 1 Score: 296.59 bits (758), Expect = 6.758e-96
Identity = 143/288 (49.65%), Postives = 196/288 (68.06%), Query Frame = 1 
Query:   70 SVLSIYAYLCKMNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEK---TMLFRNKPIEPIDILTPASSPMES 924
            S  S +A +CK     PAP+S++E A+   + C+Y+ +I+   A+SG   R++RVYADG+YD+FH GHARQL+QAKN FPN+YLI GVCND  T+  KG+TVM   ERYE VRHCRYVDE++ +APW+   +F+  +KIDFVAHDDIPY    + D+Y  LK + MF+AT+RTEGVST+D+++RIVKDYD Y+RRN+ RG S ++LN+SF+ EK  + Q K   LK +GK      K  II KWE ++ +FI +F  LF +     L+     + +  L+P  SP  S
Sbjct:  159 SGASDFATICK-----PAPYSHDEEAMLERDRCDYTQRITYQMARSGQTTRRVRVYADGIYDLFHQGHARQLMQAKNIFPNVYLIVGVCNDELTHRMKGRTVMNGFERYEGVRHCRYVDEIVQNAPWTLSDEFIADNKIDFVAHDDIPYVTDGMDDIYAPLKARGMFVATERTEGVSTSDIVARIVKDYDLYVRRNLARGYSAKELNVSFLSEKKFRLQNKMDELKSRGKRELSKVKVDIITKWEEKSREFIDTFLLLFGRENLNHLWNESKGKLLQALSPPGSPSGS 441
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Fly
Match: Pcyt1 (gene:FBgn0041342 transcript:FBtr0072738)

HSP 1 Score: 296.59 bits (758), Expect = 6.758e-96
Identity = 143/288 (49.65%), Postives = 196/288 (68.06%), Query Frame = 1 
Query:   70 SVLSIYAYLCKMNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEK---TMLFRNKPIEPIDILTPASSPMES 924
            S  S +A +CK     PAP+S++E A+   + C+Y+ +I+   A+SG   R++RVYADG+YD+FH GHARQL+QAKN FPN+YLI GVCND  T+  KG+TVM   ERYE VRHCRYVDE++ +APW+   +F+  +KIDFVAHDDIPY    + D+Y  LK + MF+AT+RTEGVST+D+++RIVKDYD Y+RRN+ RG S ++LN+SF+ EK  + Q K   LK +GK      K  II KWE ++ +FI +F  LF +     L+     + +  L+P  SP  S
Sbjct:  159 SGASDFATICK-----PAPYSHDEEAMLERDRCDYTQRITYQMARSGQTTRRVRVYADGIYDLFHQGHARQLMQAKNIFPNVYLIVGVCNDELTHRMKGRTVMNGFERYEGVRHCRYVDEIVQNAPWTLSDEFIADNKIDFVAHDDIPYVTDGMDDIYAPLKARGMFVATERTEGVSTSDIVARIVKDYDLYVRRNLARGYSAKELNVSFLSEKKFRLQNKMDELKSRGKRELSKVKVDIITKWEEKSREFIDTFLLLFGRENLNHLWNESKGKLLQALSPPGSPSGS 441
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Fly
Match: Pcyt1 (gene:FBgn0041342 transcript:FBtr0333396)

HSP 1 Score: 296.59 bits (758), Expect = 6.758e-96
Identity = 143/288 (49.65%), Postives = 196/288 (68.06%), Query Frame = 1 
Query:   70 SVLSIYAYLCKMNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEK---TMLFRNKPIEPIDILTPASSPMES 924
            S  S +A +CK     PAP+S++E A+   + C+Y+ +I+   A+SG   R++RVYADG+YD+FH GHARQL+QAKN FPN+YLI GVCND  T+  KG+TVM   ERYE VRHCRYVDE++ +APW+   +F+  +KIDFVAHDDIPY    + D+Y  LK + MF+AT+RTEGVST+D+++RIVKDYD Y+RRN+ RG S ++LN+SF+ EK  + Q K   LK +GK      K  II KWE ++ +FI +F  LF +     L+     + +  L+P  SP  S
Sbjct:  159 SGASDFATICK-----PAPYSHDEEAMLERDRCDYTQRITYQMARSGQTTRRVRVYADGIYDLFHQGHARQLMQAKNIFPNVYLIVGVCNDELTHRMKGRTVMNGFERYEGVRHCRYVDEIVQNAPWTLSDEFIADNKIDFVAHDDIPYVTDGMDDIYAPLKARGMFVATERTEGVSTSDIVARIVKDYDLYVRRNLARGYSAKELNVSFLSEKKFRLQNKMDELKSRGKRELSKVKVDIITKWEEKSREFIDTFLLLFGRENLNHLWNESKGKLLQALSPPGSPSGS 441
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Fly
Match: Pcyt1 (gene:FBgn0041342 transcript:FBtr0345365)

HSP 1 Score: 296.59 bits (758), Expect = 6.758e-96
Identity = 143/288 (49.65%), Postives = 196/288 (68.06%), Query Frame = 1 
Query:   70 SVLSIYAYLCKMNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEK---TMLFRNKPIEPIDILTPASSPMES 924
            S  S +A +CK     PAP+S++E A+   + C+Y+ +I+   A+SG   R++RVYADG+YD+FH GHARQL+QAKN FPN+YLI GVCND  T+  KG+TVM   ERYE VRHCRYVDE++ +APW+   +F+  +KIDFVAHDDIPY    + D+Y  LK + MF+AT+RTEGVST+D+++RIVKDYD Y+RRN+ RG S ++LN+SF+ EK  + Q K   LK +GK      K  II KWE ++ +FI +F  LF +     L+     + +  L+P  SP  S
Sbjct:  159 SGASDFATICK-----PAPYSHDEEAMLERDRCDYTQRITYQMARSGQTTRRVRVYADGIYDLFHQGHARQLMQAKNIFPNVYLIVGVCNDELTHRMKGRTVMNGFERYEGVRHCRYVDEIVQNAPWTLSDEFIADNKIDFVAHDDIPYVTDGMDDIYAPLKARGMFVATERTEGVSTSDIVARIVKDYDLYVRRNLARGYSAKELNVSFLSEKKFRLQNKMDELKSRGKRELSKVKVDIITKWEEKSREFIDTFLLLFGRENLNHLWNESKGKLLQALSPPGSPSGS 441
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Zebrafish
Match: pcyt1ba (phosphate cytidylyltransferase 1, choline, beta a [Source:ZFIN;Acc:ZDB-GENE-061220-4])

HSP 1 Score: 271.937 bits (694), Expect = 1.533e-88
Identity = 133/263 (50.57%), Postives = 181/263 (68.82%), Query Frame = 1 
Query:   94 LCKMNQFSPAPFSNE-ECALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLF 846
            L +     PA F+ E  C  +  ++     K++++QA  G    R +RVYADG++D+FH+GHAR L+QAKN FPN YLI GVC+D  T+  KG TVMTEDERYEA+RHCRYVDEVL DAPW+   DFLE+HKIDFVAHDDIPY +    DVYK +KE  MF+ T+RTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+S++ EK  + Q +   +KEK + + + +K            +I KWE ++ +FI +F  LF
Sbjct:   10 LPRTTLIEPAIFTPETSCECRAPHE-----KLTVDQASHGTPVDRPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHKYKGFTVMTEDERYEALRHCRYVDEVLRDAPWTLTQDFLEKHKIDFVAHDDIPYSSAGSEDVYKHIKEAGMFVPTKRTEGISTSDLITRIVRDYDVYARRNLQRGYTAKELNVSYINEKKYRLQNQVDRMKEKVRTVEEKSKHFVYRVEEKSHDLIQKWEEKSREFIGNFLELF 267
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Zebrafish
Match: pcyt1bb (phosphate cytidylyltransferase 1, choline, beta b [Source:ZFIN;Acc:ZDB-GENE-051120-48])

HSP 1 Score: 269.24 bits (687), Expect = 2.719e-87
Identity = 126/233 (54.08%), Postives = 172/233 (73.82%), Query Frame = 1 
Query:  181 KISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLF 846
            K++L QA+ G  A R +RVYADG++D+FH+GHAR L+QAKN FPN  LI GVC+DA T+  KG TVMTEDERYEA+ HCRYVDEV+ DAPW+   +FL++H+IDFVAHDDIPY +    DVYK +KE  MF+ATQRTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+ F+KEK  + Q++   +KE  + + + +K            +I KWE ++ +FI +F  LF
Sbjct:   56 KVTLAQARRGTPAQRPVRVYADGIFDLFHSGHARALMQAKNLFPNTQLIVGVCSDALTHKYKGYTVMTEDERYEALIHCRYVDEVVRDAPWTLTSEFLKKHRIDFVAHDDIPYTSAGSEDVYKHIKEAGMFVATQRTEGISTSDIITRIVRDYDVYVRRNLQRGYTARELNVGFIKEKKYRLQQQVDRMKETVRTVEEKSKHLVHRVEEKSHDLIYKWEEKSREFIGNFLELF 288
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Zebrafish
Match: pcyt1aa (phosphate cytidylyltransferase 1, choline, alpha a [Source:ZFIN;Acc:ZDB-GENE-050417-108])

HSP 1 Score: 255.758 bits (652), Expect = 8.011e-82
Identity = 126/261 (48.28%), Postives = 182/261 (69.73%), Query Frame = 1 
Query:   97 CKMNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAP-RQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            C +    PAP++++   L+ + D  Y  ++++ +A+ G  P R +RVYADG++DMFH+GHAR L+QAK  FPN +LI GVC+D  T+  KG TVM EDERY+AV HCRYVDEV+ +APW+   +FL +H+IDFVAHDDIPY + +  DVYK +K+  MF  TQRTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+SF+ EK    QE+   +K+K K + + +K            +I KWE ++ +FI +F  +F
Sbjct:   34 CTVGLKYPAPYADQ---LESMEDKQYQ-RVTIEEARRGTPPDRPVRVYADGIFDMFHSGHARALMQAKCLFPNTHLIVGVCSDDLTHKLKGFTVMNEDERYDAVSHCRYVDEVVRNAPWTLTPEFLTKHRIDFVAHDDIPYSSADSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYVRRNLQRGYTAKELNVSFINEKKYNLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGNFLQMF 290
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Zebrafish
Match: pcyt1aa (phosphate cytidylyltransferase 1, choline, alpha a [Source:ZFIN;Acc:ZDB-GENE-050417-108])

HSP 1 Score: 255.758 bits (652), Expect = 8.011e-82
Identity = 126/261 (48.28%), Postives = 182/261 (69.73%), Query Frame = 1 
Query:   97 CKMNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAP-RQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            C +    PAP++++   L+ + D  Y  ++++ +A+ G  P R +RVYADG++DMFH+GHAR L+QAK  FPN +LI GVC+D  T+  KG TVM EDERY+AV HCRYVDEV+ +APW+   +FL +H+IDFVAHDDIPY + +  DVYK +K+  MF  TQRTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+SF+ EK    QE+   +K+K K + + +K            +I KWE ++ +FI +F  +F
Sbjct:   34 CTVGLKYPAPYADQ---LESMEDKQYQ-RVTIEEARRGTPPDRPVRVYADGIFDMFHSGHARALMQAKCLFPNTHLIVGVCSDDLTHKLKGFTVMNEDERYDAVSHCRYVDEVVRNAPWTLTPEFLTKHRIDFVAHDDIPYSSADSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYVRRNLQRGYTAKELNVSFINEKKYNLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGNFLQMF 290
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Zebrafish
Match: pcyt1ab (phosphate cytidylyltransferase 1, choline, alpha b [Source:ZFIN;Acc:ZDB-GENE-050522-114])

HSP 1 Score: 242.276 bits (617), Expect = 9.713e-77
Identity = 119/254 (46.85%), Postives = 166/254 (65.35%), Query Frame = 1 
Query:  118 PAPFSNEECALKLLNDCNYSIKISLNQAKSGLAP-RQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            PAPF++E     L+   +   ++S+  A  G    R +RVYADG++DMFH+GHAR L+QAK  FPN YLI G C         G  VM EDERY+AV HCRYVDEV+ +APW+   +FL +H+IDFVAHDDIPY +    DVY+ +K+  MF  TQRTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+SF+ EK    QE    +K+K + + + +K            +I KWE ++ +FI +F  +F
Sbjct:   42 PAPFADE-----LVTPESAYARVSMEDALRGTPEERPVRVYADGIFDMFHSGHARALMQAKCLFPNTYLIVGGCTFKIVFKFDGFXVMNEDERYDAVCHCRYVDEVVRNAPWTLSPEFLAEHRIDFVAHDDIPYISAGTDDVYRHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYVRRNLQRGYTAKELNVSFINEKKYHLQEHVDKVKQKVRNVEEKSKEFVQKVEEKGIDLIQKWEEKSREFIGNFLQMF 290
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Xenopus
Match: cmtm3 (CKLF-like MARVEL transmembrane domain containing 3 [Source:Xenbase;Acc:XB-GENE-1011270])

HSP 1 Score: 272.707 bits (696), Expect = 1.930e-88
Identity = 133/259 (51.35%), Postives = 179/259 (69.11%), Query Frame = 1 
Query:  112 FSPAPFSNE---ECALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLF 846
             +PAPF+ E   EC            K+++ QA+ G    R +RVYADG++D+FH+GHAR L+QAKN FPN YL+ GVC+D  T+  KG TVM E ERYEA+RHCRYVDE++TDAPW+   +FLE+HKIDFVAHDDIPY +    DVYK +KE  MF+ TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK  +FQ +   +KEK K + + +K            +I KWE ++ +FI +F  LF
Sbjct:   42 IAPAPFAEETTYECKAP-------HEKLTIAQARIGTPVDRPVRVYADGIFDLFHSGHARALMQAKNLFPNSYLLVGVCSDELTHKYKGFTVMNETERYEALRHCRYVDEIITDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYRFQNQVDKMKEKVKNVEEKSKEFVYKVEEKSHDLIQKWEEKSREFIGNFLELF 293
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Xenopus
Match: PCYT1A (phosphate cytidylyltransferase 1, choline, alpha [Source:NCBI gene;Acc:100496938])

HSP 1 Score: 258.455 bits (659), Expect = 1.038e-82
Identity = 130/259 (50.19%), Postives = 180/259 (69.50%), Query Frame = 1 
Query:  103 MNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLA-PRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            M    PAPFS+E   LK+     Y  ++S+ +AK G    R +RVYADG++D+FH+GHAR L+QAKN FPN +LI GVC+D  T+  KG TVM E ERY+AV+HCRYVDEV+ +APW+   +FLE+H+IDFVAHDDIPY +    DVYK +K+  MF  TQRTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+SF+ EK    QE+   +K+K K + + +K            +I KWE ++ +FI +F  +F
Sbjct:   51 MGVREPAPFSDE---LKVDRSKTYR-RVSMEEAKLGTPIERPVRVYADGIFDLFHSGHARALMQAKNLFPNTHLIVGVCSDELTHNLKGFTVMNEAERYDAVQHCRYVDEVVRNAPWTLSPEFLEKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYVRRNLQRGYTAKELNVSFINEKRFNLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDMIQKWEEKSREFIGNFLEMF 305
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Xenopus
Match: PCYT1A (phosphate cytidylyltransferase 1, choline, alpha [Source:NCBI gene;Acc:100496938])

HSP 1 Score: 258.84 bits (660), Expect = 1.550e-82
Identity = 130/259 (50.19%), Postives = 180/259 (69.50%), Query Frame = 1 
Query:  103 MNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLA-PRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            M    PAPFS+E   LK+     Y  ++S+ +AK G    R +RVYADG++D+FH+GHAR L+QAKN FPN +LI GVC+D  T+  KG TVM E ERY+AV+HCRYVDEV+ +APW+   +FLE+H+IDFVAHDDIPY +    DVYK +K+  MF  TQRTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+SF+ EK    QE+   +K+K K + + +K            +I KWE ++ +FI +F  +F
Sbjct:   72 MGVREPAPFSDE---LKVDRSKTYR-RVSMEEAKLGTPIERPVRVYADGIFDLFHSGHARALMQAKNLFPNTHLIVGVCSDELTHNLKGFTVMNEAERYDAVQHCRYVDEVVRNAPWTLSPEFLEKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYVRRNLQRGYTAKELNVSFINEKRFNLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDMIQKWEEKSREFIGNFLEMF 326
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Xenopus
Match: PCYT1A (phosphate cytidylyltransferase 1, choline, alpha [Source:NCBI gene;Acc:100496938])

HSP 1 Score: 258.07 bits (658), Expect = 2.125e-82
Identity = 130/259 (50.19%), Postives = 180/259 (69.50%), Query Frame = 1 
Query:  103 MNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLA-PRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            M    PAPFS+E   LK+     Y  ++S+ +AK G    R +RVYADG++D+FH+GHAR L+QAKN FPN +LI GVC+D  T+  KG TVM E ERY+AV+HCRYVDEV+ +APW+   +FLE+H+IDFVAHDDIPY +    DVYK +K+  MF  TQRTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+SF+ EK    QE+   +K+K K + + +K            +I KWE ++ +FI +F  +F
Sbjct:   39 MGVREPAPFSDE---LKVDRSKTYR-RVSMEEAKLGTPIERPVRVYADGIFDLFHSGHARALMQAKNLFPNTHLIVGVCSDELTHNLKGFTVMNEAERYDAVQHCRYVDEVVRNAPWTLSPEFLEKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYVRRNLQRGYTAKELNVSFINEKRFNLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDMIQKWEEKSREFIGNFLEMF 293
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Xenopus
Match: pcyt2 (phosphate cytidylyltransferase 2, ethanolamine [Source:NCBI gene;Acc:496753])

HSP 1 Score: 102.064 bits (253), Expect = 1.790e-23
Identity = 52/135 (38.52%), Postives = 82/135 (60.74%), Query Frame = 1 
Query:  223 QIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIV 627
            Q+RV+ DG YDM H GH+ QL QA+      YLI GV  D + + +KG  V T++ERY+ V+  ++VDE++  AP+   L+ L+++  DF  H +      +  D Y+ +K    +   QRT+GVSTTD++ R++
Sbjct:   18 QVRVWCDGCYDMVHYGHSNQLRQARAM--GGYLIVGVHTDEEISQHKGPPVFTQEERYKMVKAIKWVDEIVPGAPYVTTLETLDKYNCDFCVHGNDITLTVDGKDTYEEVKNAGRYRECQRTQGVSTTDLVGRML 150

HSP 2 Score: 77.411 bits (189), Expect = 4.997e-15
Identity = 50/153 (32.68%), Postives = 75/153 (49.02%), Query Frame = 1 
Query:  214 APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKT--VMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAH---DDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRN 657
            +P    +Y  G +D+FH GH   L +  +     Y+I G+  D + N+ K K   +M   ER  +V  CRYV EV+  AP+S   D L+  K+D V H   D +P   G   D Y   K + +F        ++T D++ RI+K+   Y  RN
Sbjct:  205 SPGDTIIYVAGAFDLFHIGHIDFLEKVYSLAEKPYVIVGLHFDQEVNHYKRKNYPIMNIHERTLSVLACRYVAEVVIGAPYSVSADLLDHFKVDIVCHGKTDVLPDRDGS--DPYAEPKRRAIFRVVDSGNSLTTDDIVQRIIKNRLEYEARN 355
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BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Mouse
Match: Pcyt1b (phosphate cytidylyltransferase 1, choline, beta isoform [Source:MGI Symbol;Acc:MGI:2147987])

HSP 1 Score: 272.322 bits (695), Expect = 1.010e-88
Identity = 136/284 (47.89%), Postives = 191/284 (67.25%), Query Frame = 1 
Query:  115 SPAPFSNEE-CALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLFEK----TMLFRNKPIEPIDILTPASSPM 918
            +PAPF++E  C  +  ++     K+++ QA+ G    R +RVYADG++D+FH+GHAR L+QAK  FPN YL+ GVC+D  T+  KG TVM E ERYEA+RHCRYVDEV+ DAPW+   +FLE+HKIDFVAHDDIPY +    DVYK +KE  MF+ TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK  +FQ +   +KEK K + + +K            +I KWE ++ +FI +F  LF        +F+ +    +  L+P  SP+
Sbjct:   13 APAPFADESSCQCQAPHE-----KLTVAQARLGTPVDRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPV 291
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Mouse
Match: Pcyt1b (phosphate cytidylyltransferase 1, choline, beta isoform [Source:MGI Symbol;Acc:MGI:2147987])

HSP 1 Score: 272.707 bits (696), Expect = 1.554e-88
Identity = 136/289 (47.06%), Postives = 193/289 (66.78%), Query Frame = 1 
Query:  100 KMNQFSPAPFSNEE-CALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLFEK----TMLFRNKPIEPIDILTPASSPM 918
            ++   +PAPF++E  C  +  ++     K+++ QA+ G    R +RVYADG++D+FH+GHAR L+QAK  FPN YL+ GVC+D  T+  KG TVM E ERYEA+RHCRYVDEV+ DAPW+   +FLE+HKIDFVAHDDIPY +    DVYK +KE  MF+ TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK  +FQ +   +KEK K + + +K            +I KWE ++ +FI +F  LF        +F+ +    +  L+P  SP+
Sbjct:   38 RLTLTAPAPFADESSCQCQAPHE-----KLTVAQARLGTPVDRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPV 321
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Mouse
Match: Pcyt1a (phosphate cytidylyltransferase 1, choline, alpha isoform [Source:MGI Symbol;Acc:MGI:88557])

HSP 1 Score: 253.062 bits (645), Expect = 7.454e-81
Identity = 127/264 (48.11%), Postives = 180/264 (68.18%), Query Frame = 1 
Query:   97 CKMNQFSPAPFSNEECALKLLNDCNYS---IKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            C +    PAPFS+E        + ++S   +++++ +A  G    R +RVYADG++D+FH+GHAR L+QAKN FPN YLI GVC+D  T+  KG TVM E+ERY+AV+HCRYVDEV+ +APW+   +FL +H+IDFVAHDDIPY +    DVYK +K+  MF  TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK    QE+   +K+K K + + +K            +I KWE ++ +FI SF  +F
Sbjct:   37 CAVGLRQPAPFSDE-------IEVDFSKPYVRVTMEEACRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMF 293
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Mouse
Match: Pcyt1a (phosphate cytidylyltransferase 1, choline, alpha isoform [Source:MGI Symbol;Acc:MGI:88557])

HSP 1 Score: 253.062 bits (645), Expect = 7.454e-81
Identity = 127/264 (48.11%), Postives = 180/264 (68.18%), Query Frame = 1 
Query:   97 CKMNQFSPAPFSNEECALKLLNDCNYS---IKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            C +    PAPFS+E        + ++S   +++++ +A  G    R +RVYADG++D+FH+GHAR L+QAKN FPN YLI GVC+D  T+  KG TVM E+ERY+AV+HCRYVDEV+ +APW+   +FL +H+IDFVAHDDIPY +    DVYK +K+  MF  TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK    QE+   +K+K K + + +K            +I KWE ++ +FI SF  +F
Sbjct:   37 CAVGLRQPAPFSDE-------IEVDFSKPYVRVTMEEACRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMF 293
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Mouse
Match: Pcyt1a (phosphate cytidylyltransferase 1, choline, alpha isoform [Source:MGI Symbol;Acc:MGI:88557])

HSP 1 Score: 253.062 bits (645), Expect = 7.454e-81
Identity = 127/264 (48.11%), Postives = 180/264 (68.18%), Query Frame = 1 
Query:   97 CKMNQFSPAPFSNEECALKLLNDCNYS---IKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            C +    PAPFS+E        + ++S   +++++ +A  G    R +RVYADG++D+FH+GHAR L+QAKN FPN YLI GVC+D  T+  KG TVM E+ERY+AV+HCRYVDEV+ +APW+   +FL +H+IDFVAHDDIPY +    DVYK +K+  MF  TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK    QE+   +K+K K + + +K            +I KWE ++ +FI SF  +F
Sbjct:   37 CAVGLRQPAPFSDE-------IEVDFSKPYVRVTMEEACRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMF 293
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BLAST of Choline-phosphate cytidylyltransferase B vs. UniProt/SwissProt
Match: sp|Q9Y5K3|PCY1B_HUMAN (Choline-phosphate cytidylyltransferase B OS=Homo sapiens OX=9606 GN=PCYT1B PE=1 SV=1)

HSP 1 Score: 274.248 bits (700), Expect = 3.569e-88
Identity = 137/289 (47.40%), Postives = 194/289 (67.13%), Query Frame = 1 
Query:  100 KMNQFSPAPFSNE-ECALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLFEK----TMLFRNKPIEPIDILTPASSPM 918
            ++   +PAPF++E  C  +  ++     K+++ QA+ G  A R +RVYADG++D+FH+GHAR L+QAK  FPN YL+ GVC+D  T+  KG TVM E ERYEA+RHCRYVDEV+ DAPW+   +FLE+HKIDFVAHDDIPY +    DVYK +KE  MF+ TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK  +FQ +   +KEK K + + +K            +I KWE ++ +FI +F  LF        +F+ +    +  L+P  SP+
Sbjct:   38 RLTLTAPAPFADETNCQCQAPHE-----KLTIAQARLGTPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPV 321
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BLAST of Choline-phosphate cytidylyltransferase B vs. UniProt/SwissProt
Match: sp|Q9QZC4|PCY1B_RAT (Choline-phosphate cytidylyltransferase B OS=Rattus norvegicus OX=10116 GN=Pcyt1b PE=1 SV=1)

HSP 1 Score: 273.092 bits (697), Expect = 9.046e-88
Identity = 136/289 (47.06%), Postives = 193/289 (66.78%), Query Frame = 1 
Query:  100 KMNQFSPAPFSNEE-CALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLFEK----TMLFRNKPIEPIDILTPASSPM 918
            ++   +PAPF++E  C  +  ++     K+++ QA+ G    R +RVYADG++D+FH+GHAR L+QAK  FPN YL+ GVC+D  T+  KG TVM E ERYEA+RHCRYVDEV+ DAPW+   +FLE+HKIDFVAHDDIPY +    DVYK +KE  MF+ TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK  +FQ +   +KEK K + + +K            +I KWE ++ +FI +F  LF        +F+ +    +  L+P  SP+
Sbjct:   38 RLTLTAPAPFADESSCQCQAPHE-----KLTIAQARLGTPVDRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPV 321
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. UniProt/SwissProt
Match: sp|Q811Q9|PCY1B_MOUSE (Choline-phosphate cytidylyltransferase B OS=Mus musculus OX=10090 GN=Pcyt1b PE=1 SV=2)

HSP 1 Score: 272.707 bits (696), Expect = 1.087e-87
Identity = 136/289 (47.06%), Postives = 193/289 (66.78%), Query Frame = 1 
Query:  100 KMNQFSPAPFSNEE-CALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLFEK----TMLFRNKPIEPIDILTPASSPM 918
            ++   +PAPF++E  C  +  ++     K+++ QA+ G    R +RVYADG++D+FH+GHAR L+QAK  FPN YL+ GVC+D  T+  KG TVM E ERYEA+RHCRYVDEV+ DAPW+   +FLE+HKIDFVAHDDIPY +    DVYK +KE  MF+ TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK  +FQ +   +KEK K + + +K            +I KWE ++ +FI +F  LF        +F+ +    +  L+P  SP+
Sbjct:   38 RLTLTAPAPFADESSCQCQAPHE-----KLTVAQARLGTPVDRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPV 321
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. UniProt/SwissProt
Match: sp|P49583|PCY1_CAEEL (Putative choline-phosphate cytidylyltransferase OS=Caenorhabditis elegans OX=6239 GN=F08C6.2 PE=3 SV=2)

HSP 1 Score: 258.07 bits (658), Expect = 5.095e-82
Identity = 122/245 (49.80%), Postives = 165/245 (67.35%), Query Frame = 1 
Query:  118 PAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEK 852
            PAPFS+E  A+      +YS KI+L  A++  A R +R+YADG+YD+FH GHA QL Q K  FPN+YLI GVC D DT+  KG+TV +E+ERY+ VRHCRYVDEV  +APW   ++FL+  K+DF+AHD IPY A    D+Y+  + + MFL T+RTEGVST+DV+ RI++DYD Y+RRN+QRG S ++LN+ F+     Q Q K   LK KG          ++  W+S+++D IR F   F K
Sbjct:   45 PAPFSDEALAITTREAVDYSKKITLAMAEANEAGRPVRIYADGIYDLFHHGHANQLRQVKKMFPNVYLIVGVCGDRDTHKYKGRTVTSEEERYDGVRHCRYVDEVYREAPWFCTVEFLKNLKVDFIAHDAIPYVAPGEEDLYEKFRREGMFLETERTEGVSTSDVVCRIIRDYDKYVRRNLQRGYSPKELNVGFLAASKYQIQNKVDSLKSKGI--------ELLSTWKSKSDDIIRDFIDTFHK 281
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. UniProt/SwissProt
Match: sp|P49585|PCY1A_HUMAN (Choline-phosphate cytidylyltransferase A OS=Homo sapiens OX=9606 GN=PCYT1A PE=1 SV=2)

HSP 1 Score: 256.529 bits (654), Expect = 2.461e-81
Identity = 128/264 (48.48%), Postives = 180/264 (68.18%), Query Frame = 1 
Query:   97 CKMNQFSPAPFSNEECALKLLNDCNYS---IKISLNQAKSGLA-PRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            C +    PAPFS+E        + ++S   +++++ +A  G    R +RVYADG++D+FH+GHAR L+QAKN FPN YLI GVC+D  T+  KG TVM E+ERY+AV+HCRYVDEV+ +APW+   +FL +H+IDFVAHDDIPY +    DVYK +KE  MF  TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+SF+ EK    QE+   +K+K K + + +K            +I KWE ++ +FI SF  +F
Sbjct:   37 CAVGLRQPAPFSDE-------IEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMF 293
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. TrEMBL
Match: A0A3R7SYX4 (Putative choline-phosphate cytidylyltransferase A-like isoform X4 OS=Penaeus vannamei OX=6689 GN=C7M84_024483 PE=4 SV=1)

HSP 1 Score: 328.561 bits (841), Expect = 4.084e-107
Identity = 157/293 (53.58%), Postives = 209/293 (71.33%), Query Frame = 1 
Query:   58 SLQSSVLSIYAYLCKMNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNT---KRSIIDKWESRANDFIRSFTYLFEK----TMLFRNKPIEPIDILTPASSP 915
            S + S+  +   L K     PAPF+N+E A++    C+Y+ +I+L  A++G APR IRVYADG+YD+FH GHARQL+QAKN FPN+YLI GVC+D+ T+  KG+TVM+EDERYEAVRHCRYVDEV+ DAPWS   +FL++HKIDFVAHDDIPY  G   DVY  +KE+ MF+ T+RTEGVST+DV+SRIVKDYD Y+RRN+ RG S +DLN+S++ EK  + Q K   LK+KGK ++++    K  +I KWE ++ +FI +F  LF +    T     K    +  L+P SSP
Sbjct:   21 SKEFSLAPVAPPLKKPTICKPAPFTNDEEAIRDREACDYTQRITLEMARAGKAPRPIRVYADGIYDLFHQGHARQLMQAKNLFPNVYLIVGVCSDSLTHSRKGRTVMSEDERYEAVRHCRYVDEVVPDAPWSLDDEFLDKHKIDFVAHDDIPYTTGSATDVYAHIKERGMFVTTERTEGVSTSDVVSRIVKDYDVYVRRNLARGYSAKDLNVSYINEKKYRLQNKIDDLKKKGKEMFEDIEGKKTDLISKWEEKSREFIDTFLMLFGRDGRLTQYLTEKKDSVMSALSPPSSP 313
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. TrEMBL
Match: A0A267H911 (CTP_transf_like domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig001873g2 PE=4 SV=1)

HSP 1 Score: 329.717 bits (844), Expect = 1.287e-106
Identity = 150/247 (60.73%), Postives = 191/247 (77.33%), Query Frame = 1 
Query:  106 NQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLF 846
            N   PAPFS++  A  +L   +YS+K+SL  AK+G + R +RVYADG+YDMFH+GHARQL+QAK AFPN YLI GVCND DT+  KG TVM E ERYEAVRHCRYVDEVL DAPWSY  DFL +HKIDFVAHDD+PY AG   DVYK++K++ MFLAT+RTEG+STTDVI+RI+ DYD YLRRN++RGLSR++L IS++KEK LQ +E +  ++++       T+R +I KWE ++N F+  F  +F
Sbjct:   68 NHVRPAPFSDDPDAQAILQATDYSVKVSLEDAKAGRSARPVRVYADGIYDMFHSGHARQLMQAKMAFPNAYLIVGVCNDVDTHRMKGNTVMRESERYEAVRHCRYVDEVLRDAPWSYDYDFLSKHKIDFVAHDDLPYGAGNTEDVYKWIKDRGMFLATERTEGISTTDVIARIILDYDVYLRRNLKRGLSRKELGISYMKEKELQVKETFSTMRDR----IGQTRRELIGKWEQQSNRFVSGFVSVF 310
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. TrEMBL
Match: A0A1I8G8G1 (CTP_transf_like domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 329.331 bits (843), Expect = 1.487e-106
Identity = 150/247 (60.73%), Postives = 191/247 (77.33%), Query Frame = 1 
Query:  106 NQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLF 846
            N   PAPFS++  A  +L   +YS+K+SL  AK+G + R +RVYADG+YDMFH+GHARQL+QAK AFPN YLI GVCND DT+  KG TVM E ERYEAVRHCRYVDEVL DAPWSY  DFL +HKIDFVAHDD+PY AG   DVYK++K++ MFLAT+RTEG+STTDVI+RI+ DYD YLRRN++RGLSR++L IS++KEK LQ +E +  ++++       T+R +I KWE ++N F+  F  +F
Sbjct:   65 NHVRPAPFSDDPDAQAILQATDYSVKVSLEDAKAGRSARPVRVYADGIYDMFHSGHARQLMQAKMAFPNAYLIVGVCNDVDTHRMKGNTVMRESERYEAVRHCRYVDEVLRDAPWSYDYDFLSKHKIDFVAHDDLPYGAGNTEDVYKWIKDRGMFLATERTEGISTTDVIARIILDYDVYLRRNLKRGLSRKELGISYMKEKELQVKETFSTMRDR----IGQTRRELIGKWEQQSNRFVSGFVSVF 307
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. TrEMBL
Match: A0A267GE27 (CTP_transf_like domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002562g1 PE=4 SV=1)

HSP 1 Score: 328.561 bits (841), Expect = 2.981e-106
Identity = 150/247 (60.73%), Postives = 191/247 (77.33%), Query Frame = 1 
Query:  106 NQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLF 846
            N   PAPFS++  A  +L   +YS+K+SL  AK+G + R +RVYADG+YDMFH+GHARQL+QAK AFPN YLI GVCND DT+  KG TVM E ERYEAVRHCRYVDEVL DAPWSY  DFL +HKIDFVAHDD+PY AG   DVYK++K++ MFLAT+RTEG+STTDVI+RI+ DYD YLRRN++RGLSR++L IS++KEK LQ +E +  ++++       T+R +I KWE ++N F+  F  +F
Sbjct:   68 NHVRPAPFSDDPDAQAILQATDYSVKVSLEDAKAGRSVRPVRVYADGIYDMFHSGHARQLMQAKMAFPNAYLIVGVCNDVDTHRMKGNTVMRESERYEAVRHCRYVDEVLRDAPWSYDYDFLSKHKIDFVAHDDLPYGAGNTEDVYKWIKDRGMFLATERTEGISTTDVIARIILDYDVYLRRNLKRGLSRKELGISYMKEKELQVKETFSTMRDR----IGQTRRELIGKWEQQSNRFVSGFVSVF 310
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. TrEMBL
Match: A0A1I8G367 (CTP_transf_like domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 328.561 bits (841), Expect = 2.987e-106
Identity = 150/247 (60.73%), Postives = 191/247 (77.33%), Query Frame = 1 
Query:  106 NQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLF 846
            N   PAPFS++  A  +L   +YS+K+SL  AK+G + R +RVYADG+YDMFH+GHARQL+QAK AFPN YLI GVCND DT+  KG TVM E ERYEAVRHCRYVDEVL DAPWSY  DFL +HKIDFVAHDD+PY AG   DVYK++K++ MFLAT+RTEG+STTDVI+RI+ DYD YLRRN++RGLSR++L IS++KEK LQ +E +  ++++       T+R +I KWE ++N F+  F  +F
Sbjct:   65 NHVRPAPFSDDPDAQAILQATDYSVKVSLEDAKAGRSVRPVRVYADGIYDMFHSGHARQLMQAKMAFPNAYLIVGVCNDVDTHRMKGNTVMRESERYEAVRHCRYVDEVLRDAPWSYDYDFLSKHKIDFVAHDDLPYGAGNTEDVYKWIKDRGMFLATERTEGISTTDVIARIILDYDVYLRRNLKRGLSRKELGISYMKEKELQVKETFSTMRDR----IGQTRRELIGKWEQQSNRFVSGFVSVF 307
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Cavefish
Match: pcyt1ba (phosphate cytidylyltransferase 1, choline, beta [Source:NCBI gene;Acc:103043836])

HSP 1 Score: 272.322 bits (695), Expect = 7.560e-89
Identity = 137/285 (48.07%), Postives = 190/285 (66.67%), Query Frame = 1 
Query:  118 PAPFSNE-ECALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLFEK----TMLFRNKPIEPIDILTPASSPMES 924
            PA F+ E  C  +  ++     K++++QA+ G    R +RVYADG++D+FH+GHAR L+QAKN FPN YLI GVC+D  T+  KG TVMTEDERYEA+RHCRYVDEV+ DAPW+   +FLE+HKIDFVAHDDIPY +    DVYK +KE  MF+ TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+S++ EK  + Q +   +KEK + + + +K            +I KWE ++ +FI +F  LF        +F+ +    I   +P  SP  S
Sbjct:   18 PAIFAKETSCECRAPHE-----KLTVDQARLGTPVDRPVRVYADGIFDLFHSGHARALMQAKNLFPNSYLIVGVCSDELTHKYKGFTVMTEDERYEALRHCRYVDEVVRDAPWTLTQEFLEKHKIDFVAHDDIPYSSAGSEDVYKHIKEAGMFVPTQRTEGISTSDLITRIVRDYDVYARRNLQRGYTAKELNVSYINEKKYRLQNQVDRMKEKVRTVEEKSKHFVYRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGTWKQMFQERSGRMIQAFSPHGSPGSS 297
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Cavefish
Match: pcyt1ba (phosphate cytidylyltransferase 1, choline, beta [Source:NCBI gene;Acc:103043836])

HSP 1 Score: 272.707 bits (696), Expect = 8.449e-89
Identity = 137/285 (48.07%), Postives = 190/285 (66.67%), Query Frame = 1 
Query:  118 PAPFSNE-ECALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLFEK----TMLFRNKPIEPIDILTPASSPMES 924
            PA F+ E  C  +  ++     K++++QA+ G    R +RVYADG++D+FH+GHAR L+QAKN FPN YLI GVC+D  T+  KG TVMTEDERYEA+RHCRYVDEV+ DAPW+   +FLE+HKIDFVAHDDIPY +    DVYK +KE  MF+ TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+S++ EK  + Q +   +KEK + + + +K            +I KWE ++ +FI +F  LF        +F+ +    I   +P  SP  S
Sbjct:   24 PAIFAKETSCECRAPHE-----KLTVDQARLGTPVDRPVRVYADGIFDLFHSGHARALMQAKNLFPNSYLIVGVCSDELTHKYKGFTVMTEDERYEALRHCRYVDEVVRDAPWTLTQEFLEKHKIDFVAHDDIPYSSAGSEDVYKHIKEAGMFVPTQRTEGISTSDLITRIVRDYDVYARRNLQRGYTAKELNVSYINEKKYRLQNQVDRMKEKVRTVEEKSKHFVYRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGTWKQMFQERSGRMIQAFSPHGSPGSS 303
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Cavefish
Match: pcyt1ab (choline-phosphate cytidylyltransferase A-like [Source:NCBI gene;Acc:103031553])

HSP 1 Score: 265.774 bits (678), Expect = 5.270e-86
Identity = 132/277 (47.65%), Postives = 184/277 (66.43%), Query Frame = 1 
Query:   49 KIPSLQSSVLSIYAYLCKMNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            KIP L S +              PAPF+++   ++      Y+ ++SL +A+ G  A R +RVYADG++DMFH+GHAR L+QAK  FPN +LI GVC+D  T+  KG TVM EDERY+AV HCRYVDEV+ DAPW+   +FL +H+IDFVAHDDIPY +    DVYK +KE  MF  TQRTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+SF+ EK    QE+   +K+K + + + +K            +I KWE ++ +FI +F  +F
Sbjct:   30 KIPRLTSGLTD------------PAPFADQLEVVR----AKYT-RVSLEEARRGTPANRPVRVYADGIFDMFHSGHARALMQAKRLFPNTHLIVGVCSDGLTHKLKGFTVMNEDERYDAVSHCRYVDEVVRDAPWTLTAEFLTEHRIDFVAHDDIPYVSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYVRRNLQRGYTAKELNVSFINEKKYNLQERVDKVKQKVRDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGNFLQMF 289
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Cavefish
Match: pcyt1ab (choline-phosphate cytidylyltransferase A-like [Source:NCBI gene;Acc:103031553])

HSP 1 Score: 265.774 bits (678), Expect = 5.270e-86
Identity = 132/277 (47.65%), Postives = 184/277 (66.43%), Query Frame = 1 
Query:   49 KIPSLQSSVLSIYAYLCKMNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            KIP L S +              PAPF+++   ++      Y+ ++SL +A+ G  A R +RVYADG++DMFH+GHAR L+QAK  FPN +LI GVC+D  T+  KG TVM EDERY+AV HCRYVDEV+ DAPW+   +FL +H+IDFVAHDDIPY +    DVYK +KE  MF  TQRTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+SF+ EK    QE+   +K+K + + + +K            +I KWE ++ +FI +F  +F
Sbjct:   30 KIPRLTSGLTD------------PAPFADQLEVVR----AKYT-RVSLEEARRGTPANRPVRVYADGIFDMFHSGHARALMQAKRLFPNTHLIVGVCSDGLTHKLKGFTVMNEDERYDAVSHCRYVDEVVRDAPWTLTAEFLTEHRIDFVAHDDIPYVSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYVRRNLQRGYTAKELNVSFINEKKYNLQERVDKVKQKVRDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGNFLQMF 289
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Cavefish
Match: pcyt1aa (choline-phosphate cytidylyltransferase A [Source:NCBI gene;Acc:103040438])

HSP 1 Score: 265.774 bits (678), Expect = 7.076e-86
Identity = 126/254 (49.61%), Postives = 178/254 (70.08%), Query Frame = 1 
Query:  118 PAPFSNEECALKLLNDCNYSIKISLNQAKSGLAP-RQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            PAP+++E   L  + +  Y  ++S+ +AK G  P R +RVYADG++DMFH+GHAR L+QAK  FPN +LI GVC+D  T+  KG TVM EDERY+AV HCRYVDEV+ +APW+   +FL +H+IDFVAHDDIPY +    DVYK +K+  MF  TQRTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+SF+ EK    QE+   +K+K + + + +K            +I KWE ++ +FI +F  +F
Sbjct:   42 PAPYADE---LDPMENKPYK-RVSMEEAKRGTPPERPVRVYADGIFDMFHSGHARALMQAKGLFPNTHLIVGVCSDELTHKLKGFTVMNEDERYDAVTHCRYVDEVVRNAPWTLTPEFLTKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYVRRNLQRGYTAKELNVSFINEKKYHLQERVDKVKQKVRDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGNFLQMF 291
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Yeast
Match: PCT1 (Cholinephosphate cytidylyltransferase; a rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding; contains an element within the regulatory domain involved in both silencing and activation of enzymatic activity [Source:SGD;Acc:S000003434])

HSP 1 Score: 208.764 bits (530), Expect = 4.345e-64
Identity = 97/193 (50.26%), Postives = 139/193 (72.02%), Query Frame = 1 
Query:  220 RQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQE---KYRHLKEKGKCIYDNTKRSI 789
            R IR+YADGV+D+FH GH +QL Q K AFPN+ LI GV +D  T+  KG TV+T+ +R E + HCR+VDEV+ +APW    +FL +HKID+VAHDDIPY + +  D+YK +KE   FL TQRT GVST+D+I++I++DYD YL RN  RG +RQ+LN+S++K+  L+F++   ++R   +K +   +N  R +
Sbjct:  102 RPIRIYADGVFDLFHLGHMKQLEQCKKAFPNVTLIVGVPSDKITHKLKGLTVLTDKQRCETLTHCRWVDEVVPNAPWCVTPEFLLEHKIDYVAHDDIPYVSADSDDIYKPIKEMGKFLTTQRTNGVSTSDIITKIIRDYDKYLMRNFARGATRQELNVSWLKKNELEFKKHINEFRSYFKKNQTNLNNASRDL 294
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Yeast
Match: ECT1 (Ethanolamine-phosphate cytidylyltransferase; catalyzes the second step of phosphatidylethanolamine biosynthesis; involved in the maintenance of plasma membrane; similar to mammalian CTP: phosphocholine cytidylyl-transferases; inability of the null mutant to synthesize phosphatidylethanolamine and phosphatidylcholine from ethanolamine is functionally complemented by human PCYT2 [Source:SGD;Acc:S000003239])

HSP 1 Score: 95.9005 bits (237), Expect = 7.881e-23
Identity = 56/137 (40.88%), Postives = 79/137 (57.66%), Query Frame = 1 
Query:  229 RVYADGVYDMFHAGHARQLLQAKNAFP--NIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAH-DDIPYEA-GEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIV 627
            +V+ DG +D  H GHA  +LQA+      N  L  GV  D D  +NKG  VM   ERYE  R  R+  EV+  AP+    +++++++  +V H DDI  +A GE  D YK +KE   F   +RT GVSTT++I RI+
Sbjct:    9 KVWIDGCFDFTHHGHAGAILQARRTVSKENGKLFCGVHTDEDIQHNKGTPVMNSSERYEHTRSNRWCSEVVEAAPYVTDPNWMDKYQCQYVVHGDDITIDANGE--DCYKLVKEMGRFKVVKRTYGVSTTEIIHRIL 143

HSP 2 Score: 50.447 bits (119), Expect = 1.799e-7
Identity = 41/149 (27.52%), Postives = 69/149 (46.31%), Query Frame = 1 
Query:  232 VYADGVYDMFHAGHARQLLQAK-NAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLS 675
            VY DG +D+FH G   QL + K +  P+  LI G+     T  +   T+MT  ER  +V  C+YVD V+ DA  +     + Q+  +        Y  G  V          +  A + +E ++   ++ R+    + Y+ RN ++G+S
Sbjct:  200 VYVDGDFDLFHMGDIDQLRKLKMDLHPDKKLIVGI-----TTSDYSSTIMTMKERVLSVLSCKYVDAVIIDADATS----MSQYNCE-------KYHIGTAV----------LTAAGKFSEYLTKELIVKRVESQREVYIARNQKKGMS 322
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Nematostella
Match: EDO39372 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAC0])

HSP 1 Score: 207.994 bits (528), Expect = 1.506e-66
Identity = 99/165 (60.00%), Postives = 127/165 (76.97%), Query Frame = 1 
Query:  220 RQIRVYADGVYDMFHAGHARQLLQAKNAFPN-IYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAG--EVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVK 705
            R IRVYADG+YD FH GHAR L+QAK AFP  +YL+ GVC+D  T+  KG TVMTEDERY ++ H RYVDEV+ DAPW    DF++ HKIDFVAHDDIPY+    +  DVYK +K    F+AT+RTEG+ST+D+I+R+VKDYD Y+RRN+ RG + ++LN+ F+K
Sbjct:    1 RPIRVYADGIYDCFHFGHARSLMQAKRAFPTEVYLMVGVCSDELTHKLKGFTVMTEDERYMSLLHSRYVDEVIRDAPWIVSPDFIDIHKIDFVAHDDIPYKTAGMQTDDVYKDIKAMGKFVATERTEGISTSDIIARVVKDYDVYIRRNLARGYTAKELNVGFMK 165
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Nematostella
Match: EDO31320 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SY83])

HSP 1 Score: 107.842 bits (268), Expect = 3.154e-26
Identity = 54/147 (36.73%), Postives = 86/147 (58.50%), Query Frame = 1 
Query:  220 RQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNI 660
            +QIRV+ DG +DM H GHA  L QAK      +L  GV +DA+  +NKG  V  E+ERY+ VR  ++VDEV+ +AP++  L+ ++ H  +F  H D      +  D Y  +K+   +   +RT GVSTT+++ R++    S+  + +
Sbjct:   11 KQIRVWTDGCFDMVHFGHANALRQAKAM--GDWLCVGVHSDAEIAHNKGPPVFNEEERYKMVRAIKWVDEVIENAPYTTTLETMDDHGCEFCVHGDDITLTADGTDTYHIVKDAGRYKECKRTAGVSTTNLVGRMLLLTKSHFDKGV 155

HSP 2 Score: 76.6406 bits (187), Expect = 1.539e-15
Identity = 47/147 (31.97%), Postives = 75/147 (51.02%), Query Frame = 1 
Query:  232 VYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKT--VMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYE---AGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRN 657
            +Y  G +D+FH G    L +AK      YLI G+  D   N  KG    +M   ER  +V  CRYVD+V+  AP+S   + ++Q K+D V H + P      GE  D Y+  ++  +F        ++T D+++RI+++   +  RN
Sbjct:  207 IYTAGAFDLFHVGFLDFLEKAKAL--GDYLIVGLHTDQIVNRYKGSNYPIMNLHERVLSVLACRYVDQVIIGAPYSVSQELIDQFKVDLVVHGNTPVMNDVNGE--DPYRIPRKLGIFKTINSESTITTADIVARIIRNKLKFEERN 349
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Nematostella
Match: EDO25505 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DWA4])

HSP 1 Score: 92.4337 bits (228), Expect = 1.630e-23
Identity = 42/76 (55.26%), Postives = 60/76 (78.95%), Query Frame = 1 
Query:  484 IDFVAHDDIPYEAG--EVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVK 705
            IDFVAHDDIPY+    +  DVYK +K    F+AT+RTEG+ST+D+I+R+VKDYD Y+RRN+ RG + ++LN+ F++
Sbjct:    1 IDFVAHDDIPYKTAGMQTDDVYKDIKAMGKFVATERTEGISTSDIIARVVKDYDVYIRRNLARGYTAKELNVGFME 76
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Medaka
Match: pcyt1bb (choline-phosphate cytidylyltransferase B [Source:NCBI gene;Acc:101162151])

HSP 1 Score: 266.929 bits (681), Expect = 1.604e-86
Identity = 122/233 (52.36%), Postives = 173/233 (74.25%), Query Frame = 1 
Query:  181 KISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTK----------RSIIDKWESRANDFIRSFTYLF 846
            K+++ QA+ G  A R +RVYADG++D+FH+GHAR L+QAKN FPN +LI GVC+D  T+  KG TVMTE+ERY+A+RHCRYVDEV+ DAPW+   +FL++HKIDFVAHDDIPY +    DVYK +KE  MF+AT+RTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+ F+KE + + Q +   +KE  + + + +K          + +I KWE ++ +FI +F  LF
Sbjct:   49 KLTITQARKGTPANRPVRVYADGIFDLFHSGHARALMQAKNVFPNTHLIVGVCSDELTHKLKGYTVMTEEERYDALRHCRYVDEVVRDAPWTLTPEFLKKHKIDFVAHDDIPYTSAGSEDVYKHIKEAGMFVATERTEGISTSDLITRIVRDYDIYVRRNLQRGYTARELNVGFIKENTYRLQNQVDKMKETVRTVEEKSKHFVNRVEEKSQDLIHKWEEKSREFIGNFLELF 281
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Medaka
Match: pcyt1ba (phosphate cytidylyltransferase 1, choline, beta [Source:NCBI gene;Acc:101166014])

HSP 1 Score: 266.544 bits (680), Expect = 1.925e-86
Identity = 127/233 (54.51%), Postives = 168/233 (72.10%), Query Frame = 1 
Query:  181 KISLNQAKSGL-APRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQ-------EKYRHLKEKGK---CIYDNTKRSIIDKWESRANDFIRSFTYLF 846
            K+++ QA+ G    R +RVYADG++D+FH+GHAR L+QAKN FPN YL+ GVC+D  T+  KG TVMTE ERYEA+RHCRYVDEVL DAPW+    FL++HKIDFVAHDDIPY +    DVYK +KE  MF+ TQRTEG+ST+D+I+RIV+DYD Y RRN+QRG + ++LN+S++ EK  + Q       EK R ++EK K   C  +     +I KWE ++ +FI +F  LF
Sbjct:   35 KLTIEQARRGTPVDRPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLLVGVCSDELTHKYKGFTVMTEQERYEALRHCRYVDEVLRDAPWTLTPKFLDKHKIDFVAHDDIPYSSAGSEDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSYINEKKYRLQNQVDRMKEKVRTVEEKSKHFVCRVEEKSHDLIQKWEEKSREFIGNFLELF 267
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Medaka
Match: pcyt1aa (phosphate cytidylyltransferase 1, choline, alpha [Source:NCBI gene;Acc:101157809])

HSP 1 Score: 262.692 bits (670), Expect = 1.110e-84
Identity = 124/261 (47.51%), Postives = 178/261 (68.20%), Query Frame = 1 
Query:   97 CKMNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAP-RQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            C +   +PAPF++E     +  D     ++++ +AK G  P R +RVYADG++D+FH+GHAR L+QAK  FPN +LI GVC+D  T+  KG TVM EDERY+A+ HCRYVDEV+ +APW+   +FL +H+IDFVAHDDIPY +    DVYK +K+  MF  TQRTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+SF+ EK    QE+   +K K + + + +K            +I KWE ++ +FI +F  +F
Sbjct:   36 CTVGLRNPAPFADE-----IKPDGKPYKRVTMEEAKRGTPPDRPVRVYADGIFDVFHSGHARALMQAKRLFPNTHLIVGVCSDDLTHKYKGFTVMNEDERYDAITHCRYVDEVVRNAPWTLTPEFLAKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYVRRNLQRGYTAKELNVSFINEKKYHLQERVDKVKRKVRDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGNFLQMF 291
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Medaka
Match: pcyt1aa (phosphate cytidylyltransferase 1, choline, alpha [Source:NCBI gene;Acc:101157809])

HSP 1 Score: 262.307 bits (669), Expect = 4.128e-84
Identity = 124/261 (47.51%), Postives = 178/261 (68.20%), Query Frame = 1 
Query:   97 CKMNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAP-RQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            C +   +PAPF++E     +  D     ++++ +AK G  P R +RVYADG++D+FH+GHAR L+QAK  FPN +LI GVC+D  T+  KG TVM EDERY+A+ HCRYVDEV+ +APW+   +FL +H+IDFVAHDDIPY +    DVYK +K+  MF  TQRTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+SF+ EK    QE+   +K K + + + +K            +I KWE ++ +FI +F  +F
Sbjct:   36 CTVGLRNPAPFADE-----IKPDGKPYKRVTMEEAKRGTPPDRPVRVYADGIFDVFHSGHARALMQAKRLFPNTHLIVGVCSDDLTHKYKGFTVMNEDERYDAITHCRYVDEVVRNAPWTLTPEFLAKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYVRRNLQRGYTAKELNVSFINEKKYHLQERVDKVKRKVRDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGNFLQMF 291
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Medaka
Match: pcyt1aa (phosphate cytidylyltransferase 1, choline, alpha [Source:NCBI gene;Acc:101157809])

HSP 1 Score: 258.84 bits (660), Expect = 1.955e-83
Identity = 129/272 (47.43%), Postives = 179/272 (65.81%), Query Frame = 1 
Query:   88 AYLCKMNQFSPAPFSNEECALKLLNDCNYSIK--------ISLNQAKSGLAP-RQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKR----------SIIDKWESRANDFIRSFTYLF 846
            A LC +NQ+    F    C L LL      IK        +++ +AK G  P R +RVYADG++D+FH+GHAR L+QAK  FPN +LI GVC+D  T+  KG TVM EDERY+A+ HCRYVDEV+ +APW+   +FL +H+IDFVAHDDIPY +    DVYK +K+  MF  TQRTEG+ST+D+I+RIV+DYD Y+RRN+QRG + ++LN+SF+ EK    QE+   +K K + + + +K            +I KWE ++ +FI +F  +F
Sbjct:    5 AALCCVNQY----FICRGCPLILLPPFADEIKPDGKPYKRVTMEEAKRGTPPDRPVRVYADGIFDVFHSGHARALMQAKRLFPNTHLIVGVCSDDLTHKYKGFTVMNEDERYDAITHCRYVDEVVRNAPWTLTPEFLAKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYVRRNLQRGYTAKELNVSFINEKKYHLQERVDKVKRKVRDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGNFLQMF 272
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Planmine SMEST
Match: SMESG000047766.1 (SMESG000047766.1)

HSP 1 Score: 281.182 bits (718), Expect = 7.257e-95
Identity = 138/144 (95.83%), Postives = 140/144 (97.22%), Query Frame = 1 
Query:  544 KFLKEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEKTMLFRNKPIEPIDILTPASSPMESDEKMEPTLNKIQFHVAE 975
            KF+K    FLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEKTMLFRNKPIEPIDILTPASSPMESDE+MEPTLNKIQFHVAE
Sbjct:   35 KFVK----FLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEKTMLFRNKPIEPIDILTPASSPMESDEEMEPTLNKIQFHVAE 174
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Planmine SMEST
Match: SMESG000047766.1 (SMESG000047766.1)

HSP 1 Score: 280.796 bits (717), Expect = 8.596e-95
Identity = 135/136 (99.26%), Postives = 136/136 (100.00%), Query Frame = 1 
Query:  568 FLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEKTMLFRNKPIEPIDILTPASSPMESDEKMEPTLNKIQFHVAE 975
            FLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEKTMLFRNKPIEPIDILTPASSPMESDE+MEPTLNKIQFHVAE
Sbjct:   36 FLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFVKEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEKTMLFRNKPIEPIDILTPASSPMESDEEMEPTLNKIQFHVAE 171
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Planmine SMEST
Match: SMESG000047771.1 (SMESG000047771.1)

HSP 1 Score: 246.128 bits (627), Expect = 6.267e-82
Identity = 115/115 (100.00%), Postives = 115/115 (100.00%), Query Frame = 1 
Query:  103 MNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAP 447
            MNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAP
Sbjct:    1 MNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAP 115
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Planmine SMEST
Match: SMESG000055917.1 (SMESG000055917.1)

HSP 1 Score: 152.14 bits (383), Expect = 2.320e-44
Identity = 73/175 (41.71%), Postives = 115/175 (65.71%), Query Frame = 1 
Query:  106 NQFSPAPFSNEECALKLL-NDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPN-IYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRI 624
            N+ SP  + + +  + +L +   +   I L+ A+ G   R IR+Y +GV+D+FH GHA   LQAK+ FP  I+++AGV ++ D    K K +M  +ER  +VRHCR+VDEV+ +APW   ++FL++H+IDF  HD  PY +G+V D+Y+ LK+++ F+ ++RTE  STT +I  I
Sbjct:   10 NRNSPLAYMSTDAEMGILRHQMGHFKPIPLHIAEKGSHGRPIRIYVEGVFDLFHYGHANLFLQAKSYFPGKIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGDVADIYEELKKQNRFIPSKRTENTSTTQIIDAI 184
[Close]
BLAST of Choline-phosphate cytidylyltransferase B vs. Planmine SMEST
Match: SMESG000055914.1 (SMESG000055914.1)

HSP 1 Score: 150.984 bits (380), Expect = 6.038e-44
Identity = 73/175 (41.71%), Postives = 114/175 (65.14%), Query Frame = 1 
Query:  106 NQFSPAPFSNEECALKLL-NDCNYSIKISLNQAKSGLAPRQIRVYADGVYDMFHAGHARQLLQAKNAFPN-IYLIAGVCNDADTNYNKGKTVMTEDERYEAVRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFLKEKDMFLATQRTEGVSTTDVISRI 624
            N  SP  + + +  + +L +   +   I L+ A+ G   R IR+Y +GV+D+FH GHA   LQAK+ FP  I+++AGV ++ D    K K +M  +ER  +VRHCR+VDEV+ +APW   ++FL++H+IDF  HD  PY +G+V D+Y+ LK+++ F+ ++RTE  STT +I  I
Sbjct:   10 NLNSPLAYMSTDAEMGILRHQMGHFKPIPLHIAEKGSHGRPIRIYVEGVFDLFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGDVADIYEELKKQNRFIPSKRTENTSTTQIIDAI 184
The following BLAST results are available for this feature:
BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PCYT1B2.973e-9047.42phosphate cytidylyltransferase 1, choline, beta [S... [more]
PCYT1B6.791e-8948.24phosphate cytidylyltransferase 1, choline, beta [S... [more]
PCYT1B7.431e-8947.40phosphate cytidylyltransferase 1, choline, beta [S... [more]
PCYT1A1.185e-8248.48phosphate cytidylyltransferase 1, choline, alpha [... [more]
PCYT1A5.125e-8248.48phosphate cytidylyltransferase 1, choline, alpha [... [more]
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BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pcyt-14.005e-8349.80Putative choline-phosphate cytidylyltransferase [... [more]
pcyt-15.004e-8349.80Putative choline-phosphate cytidylyltransferase [... [more]
Y18H1A.114.526e-8047.95pep chromosome:WBcel235:I:680408:683472:1 gene:WBG... [more]
Y18H1A.112.597e-6553.98pep chromosome:WBcel235:I:680408:683257:1 gene:WBG... [more]
Y18H1A.111.364e-6347.21pep chromosome:WBcel235:I:680479:683472:1 gene:WBG... [more]
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BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pcyt26.081e-10150.17gene:FBgn0035231 transcript:FBtr0072742[more]
Pcyt16.758e-9649.65gene:FBgn0041342 transcript:FBtr0072741[more]
Pcyt16.758e-9649.65gene:FBgn0041342 transcript:FBtr0072738[more]
Pcyt16.758e-9649.65gene:FBgn0041342 transcript:FBtr0333396[more]
Pcyt16.758e-9649.65gene:FBgn0041342 transcript:FBtr0345365[more]
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BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pcyt1ba1.533e-8850.57phosphate cytidylyltransferase 1, choline, beta a ... [more]
pcyt1bb2.719e-8754.08phosphate cytidylyltransferase 1, choline, beta b ... [more]
pcyt1aa8.011e-8248.28phosphate cytidylyltransferase 1, choline, alpha a... [more]
pcyt1aa8.011e-8248.28phosphate cytidylyltransferase 1, choline, alpha a... [more]
pcyt1ab9.713e-7746.85phosphate cytidylyltransferase 1, choline, alpha b... [more]
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BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cmtm31.930e-8851.35CKLF-like MARVEL transmembrane domain containing 3... [more]
PCYT1A1.038e-8250.19phosphate cytidylyltransferase 1, choline, alpha [... [more]
PCYT1A1.550e-8250.19phosphate cytidylyltransferase 1, choline, alpha [... [more]
PCYT1A2.125e-8250.19phosphate cytidylyltransferase 1, choline, alpha [... [more]
pcyt21.790e-2338.52phosphate cytidylyltransferase 2, ethanolamine [So... [more]
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BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pcyt1b1.010e-8847.89phosphate cytidylyltransferase 1, choline, beta is... [more]
Pcyt1b1.554e-8847.06phosphate cytidylyltransferase 1, choline, beta is... [more]
Pcyt1a7.454e-8148.11phosphate cytidylyltransferase 1, choline, alpha i... [more]
Pcyt1a7.454e-8148.11phosphate cytidylyltransferase 1, choline, alpha i... [more]
Pcyt1a7.454e-8148.11phosphate cytidylyltransferase 1, choline, alpha i... [more]
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BLAST of Choline-phosphate cytidylyltransferase B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9Y5K3|PCY1B_HUMAN3.569e-8847.40Choline-phosphate cytidylyltransferase B OS=Homo s... [more]
sp|Q9QZC4|PCY1B_RAT9.046e-8847.06Choline-phosphate cytidylyltransferase B OS=Rattus... [more]
sp|Q811Q9|PCY1B_MOUSE1.087e-8747.06Choline-phosphate cytidylyltransferase B OS=Mus mu... [more]
sp|P49583|PCY1_CAEEL5.095e-8249.80Putative choline-phosphate cytidylyltransferase OS... [more]
sp|P49585|PCY1A_HUMAN2.461e-8148.48Choline-phosphate cytidylyltransferase A OS=Homo s... [more]
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BLAST of Choline-phosphate cytidylyltransferase B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3R7SYX44.084e-10753.58Putative choline-phosphate cytidylyltransferase A-... [more]
A0A267H9111.287e-10660.73CTP_transf_like domain-containing protein (Fragmen... [more]
A0A1I8G8G11.487e-10660.73CTP_transf_like domain-containing protein OS=Macro... [more]
A0A267GE272.981e-10660.73CTP_transf_like domain-containing protein (Fragmen... [more]
A0A1I8G3672.987e-10660.73CTP_transf_like domain-containing protein OS=Macro... [more]
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BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pcyt1ba7.560e-8948.07phosphate cytidylyltransferase 1, choline, beta [S... [more]
pcyt1ba8.449e-8948.07phosphate cytidylyltransferase 1, choline, beta [S... [more]
pcyt1ab5.270e-8647.65choline-phosphate cytidylyltransferase A-like [Sou... [more]
pcyt1ab5.270e-8647.65choline-phosphate cytidylyltransferase A-like [Sou... [more]
pcyt1aa7.076e-8649.61choline-phosphate cytidylyltransferase A [Source:N... [more]
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BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
PCT14.345e-6450.26Cholinephosphate cytidylyltransferase; a rate-dete... [more]
ECT17.881e-2340.88Ethanolamine-phosphate cytidylyltransferase; catal... [more]
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BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO393721.506e-6660.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO313203.154e-2636.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO255051.630e-2355.26Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8... [more]
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BLAST of Choline-phosphate cytidylyltransferase B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pcyt1bb1.604e-8652.36choline-phosphate cytidylyltransferase B [Source:N... [more]
pcyt1ba1.925e-8654.51phosphate cytidylyltransferase 1, choline, beta [S... [more]
pcyt1aa1.110e-8447.51phosphate cytidylyltransferase 1, choline, alpha [... [more]
pcyt1aa4.128e-8447.51phosphate cytidylyltransferase 1, choline, alpha [... [more]
pcyt1aa1.955e-8347.43phosphate cytidylyltransferase 1, choline, alpha [... [more]
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BLAST of Choline-phosphate cytidylyltransferase B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000047766.17.257e-9595.83SMESG000047766.1[more]
SMESG000047766.18.596e-9599.26SMESG000047766.1[more]
SMESG000047771.16.267e-82100.00SMESG000047771.1[more]
SMESG000055917.12.320e-4441.71SMESG000055917.1[more]
SMESG000055914.16.038e-4441.71SMESG000055914.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003233 ID=SMED30003233|Name=Choline-phosphate cytidylyltransferase B|organism=Schmidtea mediterranea sexual|type=transcript|length=1148bp
TAAGTAGTTTACTATTAAGAAAAGTAAGTTGGAATTAGAAATTAACCCAA
AATCCCATCACTACAAAGCAGTGTATTGTCTATTTATGCTTATTTATGCA
AAATGAATCAATTTAGTCCAGCTCCGTTTTCCAATGAAGAATGTGCATTG
AAATTATTGAATGATTGTAATTATTCAATCAAAATATCTTTAAATCAAGC
TAAATCTGGATTAGCACCAAGGCAAATTAGAGTCTATGCAGATGGAGTTT
ATGATATGTTTCATGCCGGTCATGCAAGACAGTTGTTACAGGCTAAAAAT
GCATTTCCAAATATTTATTTAATTGCGGGGGTTTGCAATGACGCCGATAC
AAATTATAATAAAGGCAAGACAGTAATGACAGAAGATGAACGCTATGAAG
CTGTCAGACATTGTCGATATGTGGATGAAGTTTTAACAGATGCACCCTGG
TCTTATGGATTAGATTTTCTTGAACAACATAAGATTGATTTTGTTGCCCA
TGATGACATACCATATGAAGCTGGTGAAGTTGTGGATGTTTATAAATTTC
TTAAAGAGAAAGACATGTTTCTAGCCACTCAAAGAACTGAGGGAGTTTCT
ACTACTGATGTAATCAGTAGAATAGTTAAGGATTACGATAGTTATTTACG
ACGTAACATACAAAGAGGACTTTCTCGTCAAGATTTAAACATTAGCTTTG
TTAAAGAAAAAAGTCTTCAATTTCAAGAAAAATATCGTCATTTAAAGGAG
AAAGGAAAGTGCATATACGACAACACAAAACGTTCGATAATTGACAAATG
GGAATCGAGAGCCAATGATTTTATAAGATCTTTCACTTACCTTTTTGAGA
AAACCATGTTGTTCAGAAATAAACCTATTGAACCAATAGATATTCTGACA
CCAGCCAGTTCTCCCATGGAATCTGACGAGAAAATGGAGCCCACTTTGAA
TAAAATTCAATTTCACGTTGCTGAATAAATGAATCTGAAATCGAATTCAG
TTTGAAATAGAAATATAAATTTGTGATCTTATTATATATATTAATATATT
GGTTCATTCATATTAAATTACGATTTAGTGTCCACTTGTCACATACACTT
AGATATTTATTATATTTTAATAAAATTTATTAACTTTTTCAAAAAAAA
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protein sequence of SMED30003233-orf-1

>SMED30003233-orf-1 ID=SMED30003233-orf-1|Name=SMED30003233-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=292bp
MNQFSPAPFSNEECALKLLNDCNYSIKISLNQAKSGLAPRQIRVYADGVY
DMFHAGHARQLLQAKNAFPNIYLIAGVCNDADTNYNKGKTVMTEDERYEA
VRHCRYVDEVLTDAPWSYGLDFLEQHKIDFVAHDDIPYEAGEVVDVYKFL
KEKDMFLATQRTEGVSTTDVISRIVKDYDSYLRRNIQRGLSRQDLNISFV
KEKSLQFQEKYRHLKEKGKCIYDNTKRSIIDKWESRANDFIRSFTYLFEK
TMLFRNKPIEPIDILTPASSPMESDEKMEPTLNKIQFHVAE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
PLANA:0000240body wall musculature
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR014729Rossmann-like_a/b/a_fold
IPR004821Cyt_trans-like
Vocabulary: molecular function
TermDefinition
GO:0003824catalytic activity
GO:0016740transferase activity
GO:0016779nucleotidyltransferase activity
Vocabulary: biological process
TermDefinition
GO:0009058biosynthetic process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR014729Rossmann-like alpha/beta/alpha sandwich foldGENE3DG3DSA:3.40.50.620coord: 1..96
e-value: 9.7E-21
score: 76.4
NoneNo IPR availablePANTHERPTHR10739CYTIDYLYLTRANSFERASEcoord: 1..98
NoneNo IPR availablePANTHERPTHR10739:SF13CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE 1, ISOFORM A-RELATEDcoord: 1..98