CCR4-NOT transcription complex, subunit 11

Overview


Name	CCR4-NOT transcription complex, subunit 11
Smed ID	SMED30003224
Length (bp)	1326

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of CCR4-NOT transcription complex, subunit 11 (SMED30003224) t-SNE clustered cells

Violin plots show distribution of expression levels for CCR4-NOT transcription complex, subunit 11 (SMED30003224) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of CCR4-NOT transcription complex, subunit 11 (SMED30003224) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for CCR4-NOT transcription complex, subunit 11 (SMED30003224) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30003224

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X1 cell	SMED30003224	SMESG000081647.1	SmedASXL_006140	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015

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Homology

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Human
Match: CNOT11 (CCR4-NOT transcription complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:25217])

HSP 1 Score: 259.225 bits (661), Expect = 1.522e-80
Identity = 163/447 (36.47%), Postives = 250/447 (55.93%), Query Frame = 1

Query:   16 TSKDINSLLNLFTEQNSKQS-FESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDIKFG---------VGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFMLGD----QDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGG 1302
            T K+++SLL++ +E+    S FE +S  F+    K + F++G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF       L       G          G  P +    K FL+ +++     +EL KKTP Q+     GN+ Q +D+S +   + + +++LPT  KA  P I+   D      DS   +G  S  +    E L+ G  PP     RPEF R  PPLH     +E+ W+NP+  DH          +++    I  ++  A  +PL   Q  QL  +L+++P L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G
Sbjct:   64 TPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPP--RELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDP-----DS-SNSGFDSSVASQITEALVSGPKPPIESHFRPEFIRPPPPLHI--CEDELAWLNPTEPDHAIQWDKSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTG 500

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Human
Match: CNOT11 (CCR4-NOT transcription complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:25217])

HSP 1 Score: 110.923 bits (276), Expect = 1.246e-28
Identity = 54/117 (46.15%), Postives = 77/117 (65.81%), Query Frame = 1

Query:  790 LLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH 1140
            ++  A  +PL   Q  QL  +L+++P L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM 
Sbjct:    9 IMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQ 125

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Fly
Match: Not11 (gene:FBgn0034963 transcript:FBtr0072189)

HSP 1 Score: 171.4 bits (433), Expect = 1.695e-50
Identity = 104/223 (46.64%), Postives = 141/223 (63.23%), Query Frame = 1

Query:  661 FKRLQPPLHCIGTYNEMIWINPSHVDHQFMLGDQDNNEEYII----GLLKSAKTTPL-MQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGGSDG 1311
            F  + PPL  +   +E++WIN S+ D   ++ D+ N   YI      L++ A   PL +QNQ I     LK+N D+ ++    P +LP LVE NP I+ + LL L  T ++T YF+ L+ MDITLHS+EVVN LT++  LPT+FIH YI  CI +C +  DKYM  RLVRLVCVFLQSLIRNKI++++E+   I  FC+ F+ IKEA  LY+LIK    G   
Sbjct:    2 FLSIAPPL--MDFEDELLWINQSNSDKVEIIYDKSN---YITPNIKHLIEQAFLQPLSLQNQHILFDDLLKQNTDIARQYGLTPDKLPLLVESNPLISIEILLRLMTTSDITEYFNVLVNMDITLHSMEVVNRLTTSGPLPTEFIHLYISNCISTCETVKDKYMQSRLVRLVCVFLQSLIRNKIVNVRELFIEIEAFCVGFSKIKEAATLYRLIKHLETGESA 219

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Fly
Match: Not11 (gene:FBgn0034963 transcript:FBtr0343345)

HSP 1 Score: 171.4 bits (433), Expect = 1.695e-50
Identity = 104/223 (46.64%), Postives = 141/223 (63.23%), Query Frame = 1

Query:  661 FKRLQPPLHCIGTYNEMIWINPSHVDHQFMLGDQDNNEEYII----GLLKSAKTTPL-MQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGGSDG 1311
            F  + PPL  +   +E++WIN S+ D   ++ D+ N   YI      L++ A   PL +QNQ I     LK+N D+ ++    P +LP LVE NP I+ + LL L  T ++T YF+ L+ MDITLHS+EVVN LT++  LPT+FIH YI  CI +C +  DKYM  RLVRLVCVFLQSLIRNKI++++E+   I  FC+ F+ IKEA  LY+LIK    G   
Sbjct:    2 FLSIAPPL--MDFEDELLWINQSNSDKVEIIYDKSN---YITPNIKHLIEQAFLQPLSLQNQHILFDDLLKQNTDIARQYGLTPDKLPLLVESNPLISIEILLRLMTTSDITEYFNVLVNMDITLHSMEVVNRLTTSGPLPTEFIHLYISNCISTCETVKDKYMQSRLVRLVCVFLQSLIRNKIVNVRELFIEIEAFCVGFSKIKEAATLYRLIKHLETGESA 219

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Fly
Match: Not11 (gene:FBgn0034963 transcript:FBtr0072190)

HSP 1 Score: 160.614 bits (405), Expect = 3.364e-46
Identity = 103/243 (42.39%), Postives = 140/243 (57.61%), Query Frame = 1

Query:  661 FKRLQPPLHCIGTYNEMIWINPSHVDHQFMLGDQDNNEEYII----GLLKSAKTTPL-MQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQ--------------------FCLDFNSIKEANALYKLIKSANGGSDG 1311
            F  + PPL  +   +E++WIN S+ D   ++ D+ N   YI      L++ A   PL +QNQ I     LK+N D+ ++    P +LP LVE NP I+ + LL L  T ++T YF+ L+ MDITLHS+EVVN LT++  LPT+FIH YI  CI +C +  DKYM  RLVRLVCVFLQSLIRNKI++++   + I                      FC+ F+ IKEA  LY+LIK    G   
Sbjct:    2 FLSIAPPL--MDFEDELLWINQSNSDKVEIIYDKSN---YITPNIKHLIEQAFLQPLSLQNQHILFDDLLKQNTDIARQYGLTPDKLPLLVESNPLISIEILLRLMTTSDITEYFNVLVNMDITLHSMEVVNRLTTSGPLPTEFIHLYISNCISTCETVKDKYMQSRLVRLVCVFLQSLIRNKIVNVRVCATTISSTVLSDYSIVIFQELFIEIEAFCVGFSKIKEAATLYRLIKHLETGESA 239

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Zebrafish
Match: cnot11 (CCR4-NOT transcription complex, subunit 11 [Source:NCBI gene;Acc:336124])

HSP 1 Score: 248.054 bits (632), Expect = 3.096e-77
Identity = 159/440 (36.14%), Postives = 244/440 (55.45%), Query Frame = 1

Query:   22 KDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVY-----SSLISNDIKFGVGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGG 1302
            KD+++LL + +E     SFE +S  F+    K   F +G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF  +       SS      K   G  P +    K FL+ +++     +EL KKTP QV      +  Q ID+S +   + + +++LPT  KA  P ++   D      DS   +G  S  +    E L+ G  PP     RPEF R  PPL  +   +E+ W+NP   +H+      +  ++     I  ++  A  +PL   Q  QL  +L+++  L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G
Sbjct:    6 KDLSNLLGIMSEDACSSSFEQLSSAFHHCFGKAEHFGVGSVLVMLLQQPDLLPSAPQRLTALYLLWEMYRTEPLAANPFAAVFAHLLNPSSAAEEQEKTLSGFLPPITLPEKFFLSQLMLAPP--RELFKKTPRQVSCMDITSTPQTIDISGLQLALAERQSELPTQSKASFPSLLSDPD-----PDS-SNSGFDSSVANQITESLVTGPRPPLESHFRPEFIRPTPPL--LVCEDELCWLNPCEPEHRVQWDRSMCVRNGTGVEIKRIMAKAFKSPLSAAQQTQLLGELEKDLKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMSSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDNG 435

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Xenopus
Match: vwc2l.2 (von Willebrand factor C domain-containing protein 2-like, gene 2 [Source:Xenbase;Acc:XB-GENE-5737248])

HSP 1 Score: 256.144 bits (653), Expect = 4.298e-80
Identity = 162/445 (36.40%), Postives = 253/445 (56.85%), Query Frame = 1

Query:   22 KDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDIKFGV--------GDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQ--VYQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGGSD 1308
            K++++LL + TE+    +FE +S  F+    K + F++G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF   V++ L+ N     V        G  P +    K FL+ +++     +EL KKTP Q  V    ++ Q +D+S +   + + +++LPT  KA  P I+   D      DS   +G  S  +   IE L+ G  PP     RPEF R  PPLH     +E+ W+N    DH       +  +++    I  ++  A  +PL   Q  QL  +L+++P L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G +
Sbjct:    6 KELSNLLGIMTEEACSTTFEGLSAAFHHCFSKADHFRVGSVLVMLLQQPDLLPSVPQRLTALYLLWEMYRTEPLAANPFAA-VFAHLL-NPPPSAVEEVERPLSGFLPPITPPEKFFLSQLMLAPP--RELFKKTPRQIAVMDVTSLAQPVDISGLQLALAERQSELPTQSKASFPSILSDPD-----PDS-SNSGFDSSVASQIIEALVSGPKPPIESHFRPEFIRPPPPLHV--CEDELAWLNLIEPDHAIKWDRSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGEN 438

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Xenopus
Match: vwc2l.2 (von Willebrand factor C domain-containing protein 2-like, gene 2 [Source:Xenbase;Acc:XB-GENE-5737248])

HSP 1 Score: 249.21 bits (635), Expect = 2.003e-77
Identity = 159/437 (36.38%), Postives = 247/437 (56.52%), Query Frame = 1

Query:   19 SKDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDIKFGV--------GDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQ--VYQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKL 1281
             K++++LL + TE+    +FE +S  F+    K + F++G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF   V++ L+ N     V        G  P +    K FL+ +++     +EL KKTP Q  V    ++ Q +D+S +   + + +++LPT  KA  P I+   D      DS   +G  S  +   IE L+ G  PP     RPEF R  PPLH     +E+ W+N    DH       +  +++    I  ++  A  +PL   Q  QL  +L+++P L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L+++
Sbjct:    5 GKELSNLLGIMTEEACSTTFEGLSAAFHHCFSKADHFRVGSVLVMLLQQPDLLPSVPQRLTALYLLWEMYRTEPLAANPFAA-VFAHLL-NPPPSAVEEVERPLSGFLPPITPPEKFFLSQLMLAPP--RELFKKTPRQIAVMDVTSLAQPVDISGLQLALAERQSELPTQSKASFPSILSDPD-----PDS-SNSGFDSSVASQIIEALVSGPKPPIESHFRPEFIRPPPPLHV--CEDELAWLNLIEPDHAIKWDRSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRI 429

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Mouse
Match: Cnot11 (CCR4-NOT transcription complex, subunit 11 [Source:MGI Symbol;Acc:MGI:106580])

HSP 1 Score: 258.84 bits (660), Expect = 1.484e-80
Identity = 164/447 (36.69%), Postives = 252/447 (56.38%), Query Frame = 1

Query:   16 TSKDINSLLNLFTEQNSKQS-FESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDIKFG---------VGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGG 1302
            T K+++SLL++ +E+    S FE +S  F+    K + F++G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF       L       G          G  P +    K FL+ +++     +EL KKTP Q+     GN+ Q +D+S +   + + +++LPT  KA  P I+   D      DS      SS  SR + E L+ G  PP     RPEF R  PPLH     +E+ W+NP+  +H       +  +++    I  ++  A  +PL   Q  QL  +L+++P L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G
Sbjct:   59 TPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPP--RELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDP-----DSSNSGFDSSVASRIT-ESLVSGPKPPIESHFRPEFIRPPPPLHI--CEDELAWLNPTEPEHAIQWDRSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTG 495

[Close]

Query:   16 TSKDINSLLNLFTEQNSKQS-FESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDIKFG---------VGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGG 1302
            T K+++SLL++ +E+    S FE +S  F+    K + F++G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF       L       G          G  P +    K FL+ +++     +EL KKTP Q+     GN+ Q +D+S +   + + +++LPT  KA  P I+   D      DS      SS  SR + E L+ G  PP     RPEF R  PPLH     +E+ W+NP+  +H       +  +++    I  ++  A  +PL   Q  QL  +L+++P L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G
Sbjct:   59 TPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPP--RELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDP-----DSSNSGFDSSVASRIT-ESLVSGPKPPIESHFRPEFIRPPPPLHI--CEDELAWLNPTEPEHAIQWDRSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTG 495

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Mouse
Match: Cnot11 (CCR4-NOT transcription complex, subunit 11 [Source:MGI Symbol;Acc:MGI:106580])

HSP 1 Score: 138.272 bits (347), Expect = 7.613e-39
Identity = 71/131 (54.20%), Postives = 92/131 (70.23%), Query Frame = 1

Query:  802 AKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNK 1191
            A  +PL   Q  QL  +L+++P L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNK
Sbjct:    2 AFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNK 132

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BLAST of CCR4-NOT transcription complex, subunit 11 vs. UniProt/SwissProt
Match: sp|B0BNA9|CNO11_RAT (CCR4-NOT transcription complex subunit 11 OS=Rattus norvegicus OX=10116 GN=Cnot11 PE=2 SV=1)

HSP 1 Score: 259.225 bits (661), Expect = 6.816e-80
Identity = 164/447 (36.69%), Postives = 252/447 (56.38%), Query Frame = 1

Query:   16 TSKDINSLLNLFTEQNSKQS-FESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDIKFG---------VGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGG 1302
            T K+++SLL++ +E+    S FE +S  F+    K + F++G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF       L       G          G  P +    K FL+ +++     +EL KKTP Q+     GN+ Q +D+S +   + + +++LPT  KA  P I+   D      DS      SS  SR + E L+ G  PP     RPEF R  PPLH     +E+ W+NP+  +H       +  +++    I  ++  A  +PL   Q  QL  +L+++P L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G
Sbjct:   58 TPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPP--RELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDP-----DSSNSAFDSSVASRIT-ESLVSGPKPPIESHFRPEFIRPPPPLHI--CEDELAWLNPTEPEHAIQWDRSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTG 494

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BLAST of CCR4-NOT transcription complex, subunit 11 vs. UniProt/SwissProt
Match: sp|Q9UKZ1|CNO11_HUMAN (CCR4-NOT transcription complex subunit 11 OS=Homo sapiens OX=9606 GN=CNOT11 PE=1 SV=1)

HSP 1 Score: 259.225 bits (661), Expect = 7.308e-80
Identity = 163/447 (36.47%), Postives = 250/447 (55.93%), Query Frame = 1

Query:   16 TSKDINSLLNLFTEQNSKQS-FESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDIKFG---------VGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFMLGD----QDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGG 1302
            T K+++SLL++ +E+    S FE +S  F+    K + F++G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF       L       G          G  P +    K FL+ +++     +EL KKTP Q+     GN+ Q +D+S +   + + +++LPT  KA  P I+   D      DS   +G  S  +    E L+ G  PP     RPEF R  PPLH     +E+ W+NP+  DH          +++    I  ++  A  +PL   Q  QL  +L+++P L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G
Sbjct:   64 TPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPP--RELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDP-----DS-SNSGFDSSVASQITEALVSGPKPPIESHFRPEFIRPPPPLHI--CEDELAWLNPTEPDHAIQWDKSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTG 500

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BLAST of CCR4-NOT transcription complex, subunit 11 vs. UniProt/SwissProt
Match: sp|Q9CWN7|CNO11_MOUSE (CCR4-NOT transcription complex subunit 11 OS=Mus musculus OX=10090 GN=Cnot11 PE=1 SV=1)

HSP 1 Score: 258.84 bits (660), Expect = 1.038e-79
Identity = 164/447 (36.69%), Postives = 252/447 (56.38%), Query Frame = 1

Query:   16 TSKDINSLLNLFTEQNSKQS-FESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDIKFG---------VGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGG 1302
            T K+++SLL++ +E+    S FE +S  F+    K + F++G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF       L       G          G  P +    K FL+ +++     +EL KKTP Q+     GN+ Q +D+S +   + + +++LPT  KA  P I+   D      DS      SS  SR + E L+ G  PP     RPEF R  PPLH     +E+ W+NP+  +H       +  +++    I  ++  A  +PL   Q  QL  +L+++P L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G
Sbjct:   59 TPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPP--RELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDP-----DSSNSGFDSSVASRIT-ESLVSGPKPPIESHFRPEFIRPPPPLHI--CEDELAWLNPTEPEHAIQWDRSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTG 495

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. UniProt/SwissProt
Match: sp|A4QP78|CNO11_DANRE (CCR4-NOT transcription complex subunit 11 OS=Danio rerio OX=7955 GN=cnot11 PE=2 SV=1)

HSP 1 Score: 248.054 bits (632), Expect = 2.337e-76
Identity = 159/440 (36.14%), Postives = 244/440 (55.45%), Query Frame = 1

Query:   22 KDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVY-----SSLISNDIKFGVGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGG 1302
            KD+++LL + +E     SFE +S  F+    K   F +G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF  +       SS      K   G  P +    K FL+ +++     +EL KKTP QV      +  Q ID+S +   + + +++LPT  KA  P ++   D      DS   +G  S  +    E L+ G  PP     RPEF R  PPL  +   +E+ W+NP   +H+      +  ++     I  ++  A  +PL   Q  QL  +L+++  L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G
Sbjct:    6 KDLSNLLGIMSEDACSSSFEQLSSAFHHCFGKAEHFGVGSVLVMLLQQPDLLPSAPQRLTALYLLWEMYRTEPLAANPFAAVFAHLLNPSSAAEEQEKTLSGFLPPITLPEKFFLSQLMLAPP--RELFKKTPRQVSCMDITSTPQTIDISGLQLALAERQSELPTQSKASFPSLLSDPD-----PDS-SNSGFDSSVANQITESLVTGPRPPLESHFRPEFIRPTPPL--LVCEDELCWLNPCEPEHRVQWDRSMCVRNGTGVEIKRIMAKAFKSPLSAAQQTQLLGELEKDLKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMSSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDNG 435

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BLAST of CCR4-NOT transcription complex, subunit 11 vs. UniProt/SwissProt
Match: sp|Q1ZXI2|CNO11_DICDI (CCR4-NOT transcription complex subunit 11 OS=Dictyostelium discoideum OX=44689 GN=cnot11 PE=3 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 1.209e-28
Identity = 88/247 (35.63%), Postives = 131/247 (53.04%), Query Frame = 1

Query:  637 AYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFMLGD------------------------------QDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYM-HRLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLI 1284
            ++ S  P FKR +PP     ++N   WINPS ++H  +L +                                N+++ +  L+  A    L ++QI+Q++ ++  +P L       P  LP LVE N  +A D LL L ++ +   +F  LI M++   S+EVVN L + V+LP  FI  YI  CI SC++  DK M  R VRLVCVF+QSLIRN II+IK +   +  FCL+F+ I+EA +L+K I
Sbjct:  347 SFFSFEPRFKRAEPP-----SFNPTTWINPS-INHGLLLSNPMSSTVAATIAATATSAPTTILIPSPTTTTSYNSKKIVRDLMTKAIKGRLKKSQILQIKNEMDIDPKLAYYSGLTPKNLPFLVENNTQVAIDTLLKLINSPDFKDHFQTLISMEMNFRSMEVVNAL-ATVDLPPHFIPMYITNCIDSCNNIKDKAMQQRSVRLVCVFIQSLIRNNIINIKNLFCEVQTFCLEFSKIREAISLFKAI 586

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. TrEMBL
Match: A0A1I8GSL8 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig004161g1 PE=4 SV=1)

HSP 1 Score: 288.5 bits (737), Expect = 5.680e-89
Identity = 173/443 (39.05%), Postives = 262/443 (59.14%), Query Frame = 1

Query:   16 TSKDINSLLNLFT-EQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDIKFGVGDCPTLDSIGKTFLASVIIQT----QNFKELLKKTPNQ----VYQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQF-----MLGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILF--DTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKS 1290
            +SK++ +L++L T +Q +  +FE+I         K++ F++GTALVL L++ ++L N+ Q L+A +LLWEL + D    NPF      ++ S++        P L    + FL S++  T    Q  +ELLKKTP Q    V+    +  E+DLS +     +   ++P + +  +PC++   +  L   +S+  +G S+E  R  ++ LL GD       LRPEF  L PPLH +G  +E++W++P+ ++H       M     +  E    ++++ K T L Q+QI QL   + ++P L+      PS LP LVE NP +A + LL L    + +VT YFS L+ M+++LHS+EVVN LT++VELP +FIH YI  CI SC S+ DKYM  RLVRLVCVFLQSLIRNKIID+K I   +  FC++FN I+EA  L++L+KS
Sbjct:    4 SSKELGNLMSLLTLDQCANNTFENIGQQVQKYFTKQDGFKVGTALVLLLQNPDLLPNRMQQLVALYLLWELTRVDPPNVNPFQPAFVYAMRSDENDTRHFRVPCLPLQERVFLYSLLQSTHASGQPSRELLKKTPQQIANSVFPPNVIPSELDLSFLESPYAERAKEMPVVSRVAMPCVLSDPERRLASMESYSGSGSSAEAQRQVLDSLLTGDQAAVRSHLRPEFLLLAPPLHSVGIEDELVWMSPTGLEHTAQWDASMCQSGSSGAETRKLMVRAFKQT-LQQSQIRQLNEAISQDPKLISLSGMSPSRLPELVEHNPLVAIEVLLTLMKASSPQVTDYFSVLVNMEMSLHSMEVVNRLTTSVELPAEFIHLYISNCISSCESTKDKYMQNRLVRLVCVFLQSLIRNKIIDVKNIYIEVQAFCIEFNRIREAAGLFRLLKS 445

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. TrEMBL
Match: A0A1I8JG42 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig004161g2 PE=4 SV=1)

HSP 1 Score: 285.804 bits (730), Expect = 6.033e-88
Identity = 172/443 (38.83%), Postives = 261/443 (58.92%), Query Frame = 1

Query:   16 TSKDINSLLNLFT-EQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDIKFGVGDCPTLDSIGKTFLASVIIQT----QNFKELLKKTPNQ----VYQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQF-----MLGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILF--DTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKS 1290
            +SK++ +L++L T +Q +  +FE+I         K++ F++GTALVL L++ ++L N+ Q L+A +LLWEL + D    NPF      ++ S++        P L    +  L S++  T    Q  +ELLKKTP Q    V+    +  E+DLS +     +   ++P + +  +PC++   +  L   +S+  +G S+E  R  ++ LL GD       LRPEF  L PPLH +G  +E++W++P+ ++H       M     +  E    ++++ K T L Q+QI QL   + ++P L+      PS LP LVE NP +A + LL L    + +VT YFS L+ M+++LHS+EVVN LT++VELP +FIH YI  CI SC S+ DKYM  RLVRLVCVFLQSLIRNKIID+K I   +  FC++FN I+EA  L++L+KS
Sbjct:    4 SSKELGNLMSLLTLDQCANNTFENIGQQVQKYFTKQDGFKVGTALVLLLQNPDLLPNRMQQLVALYLLWELTRVDPPNVNPFQPAFVYAMRSDENDTRHFRVPCLPLQERVLLYSLLQSTHASGQPSRELLKKTPQQIANSVFPPNVIPSELDLSFLESPYAERAKEMPVVSRVAMPCVLSDPERRLASMESYSGSGSSAEAQRQVLDSLLTGDQAAVRSHLRPEFLLLAPPLHSVGIEDELVWMSPTGLEHTAQWDASMCQSGSSGAETRKLMVRAFKQT-LQQSQIRQLNEAISQDPKLISLSGMSPSRLPELVEHNPLVAIEVLLTLMKASSPQVTDYFSVLVNMEMSLHSMEVVNRLTTSVELPAEFIHLYISNCISSCESTKDKYMQNRLVRLVCVFLQSLIRNKIIDVKNIYIEVQAFCIEFNRIREAAGLFRLLKS 445

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. TrEMBL
Match: A0A0L8H4C7 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22022979mg PE=4 SV=1)

HSP 1 Score: 280.411 bits (716), Expect = 3.406e-86
Identity = 176/452 (38.94%), Postives = 275/452 (60.84%), Query Frame = 1

Query:   25 DINSLLNLFTEQNSK-QSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDNEPN-PFIDLVYSSLIS---------NDIKFGVGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQVYQ-EGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGK----SSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQ-----FMLGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGGSDGD 1314
            D+ SLL++ +E ++K Q+F++++  F+    K + F++G ALVL L+++++L N  Q L A FLL+E+ +N+   N PF  +    L +         ND+ + +     + +  + FL  +I  +   KE+ KKTP QV Q + N  Q +D++S+   + + +++LP I K+ +P I+P  D+   K  SF++ GK    + +  R +IE LL G NPP    +RPEF RL PPLH     +E++W+NP   D+       M        E +  L+  A  + L   Q  QL  +L+++P L+  I   P++LP LVE NP +A + LL L ++ ++T YFS L+ M+++LHS+EVVN LTSAVELP++FIH YI  CI +C + TD+YM  RLVRLVCVFLQSLIRNKIID+K+I   +  FC++F+ I+EA AL++L+K++     G+
Sbjct:    7 DLASLLSVLSEDSTKSQTFDNLASTFHHYFQKADHFKVGMALVLLLQNRDLLPNPTQKLAAIFLLYEMYRNEPAANNPFAPVFVHLLKATPENQDVGQNDLHWAIS---PISASERYFLCQLI--SSPVKEMFKKTPLQVIQMDVNNAQTMDITSLQITLAEKQSELPAISKSSMPSIVPDPDS---KPTSFEQFGKPGLVNQDVQRQTIEALLTGPNPPVENCMRPEFIRLAPPLHI--AEDELVWMNPFEADYTPAWDTTMCSSSTAGTE-VRCLMSLALKSSLTLQQQQQLMDELEKDPKLVYHIGLTPTKLPDLVENNPIVAIEVLLKLMESNQITEYFSVLVSMEMSLHSMEVVNRLTSAVELPSEFIHLYISNCITTCENITDRYMQNRLVRLVCVFLQSLIRNKIIDVKDIFIEVQTFCIEFSRIREAAALFRLLKNSETNGSGN 447

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. TrEMBL
Match: A0A401P250 (Uncharacterized protein OS=Scyliorhinus torazame OX=75743 GN=scyTo_0008018 PE=4 SV=1)

HSP 1 Score: 271.937 bits (694), Expect = 3.972e-83
Identity = 163/442 (36.88%), Postives = 256/442 (57.92%), Query Frame = 1

Query:   22 KDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDI-----KFGVGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQF----MLGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGGSD 1308
            K+++SL+ +  E+ +  +FE +S  F+    K + F++G+ LV+ L+  ++L + QQ L A +LLWE+ + +    NPF  +    L +  +     K  +G  P +    K FL+ +++     +EL KKTP Q+     GN+ Q +D+S +   + + +++LPT  KA  P I+P  D      DS   +G  S  +   IE L+ G  PP     RPEF R  PPLH     +E+ W+NP+  DH       +  +++    I  ++  A  +PL   Q  QL  +L+++P L+  I   P +LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G +
Sbjct:    6 KELSSLIGIICEEATSNTFEGLSTAFHHYFAKHDHFRVGSTLVMLLQQADLLPSPQQRLTALYLLWEMYRTEPLAANPFAAVFAHLLNAAPVAEEQEKQLLGFLPPITPPEKFFLSQLMLAPP--RELFKKTPRQIACMDVGNMPQSVDISGLQLALAERQSELPTQSKASFPSILPDPD-----PDS-SNSGFDSSVATQIIEALVSGPRPPIESHFRPEFIRPAPPLHV--CEDELAWLNPTEPDHTIQWDKTMCVKNSTGVEIKRIMAKAFKSPLSAQQQTQLLGELEKDPKLVYHIGLTPVKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGEN 437

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. TrEMBL
Match: A0A3P9CY27 (CCR4-NOT transcription complex, subunit 11 OS=Maylandia zebra OX=106582 PE=4 SV=1)

HSP 1 Score: 269.24 bits (687), Expect = 4.826e-82
Identity = 165/445 (37.08%), Postives = 260/445 (58.43%), Query Frame = 1

Query:   22 KDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLIS------NDIKFGVGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCII--PFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGGSD 1308
            K++++LL++ +E+    SFES+S +F+    K   F++G+ LV+ L+  ++L +  Q LIA +LLWE+ + +    NPF   V++ L++         K   G  P +    K FL+ +++     ++L KKTP QV     GN+ Q +D+S +   + + +++LPT  KA  P I+  P  D++         +G  S  +   IE L+ G  PP     RPEF R  PPLH     +E+ W+NP+  DH       +  +++    I  ++  A  +PL   Q  QL A+L+++P L+  I   P +LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G +
Sbjct:    6 KELSNLLSIISEEACTNSFESLSTHFHHYFGKAEHFRVGSVLVMLLQQPDLLPSSSQRLIALYLLWEMYRTEPLAANPFAA-VFAHLLNPAPAGEEQEKVLSGFLPPITQPEKFFLSQLMLAPP--RDLFKKTPRQVSCMDVGNMPQSVDISGLQLALAERQSELPTQSKASFPSILNDPDPDSS--------NSGFDSSVANQIIESLVTGPRPPLESHFRPEFIRPPPPLHV--CEDELAWLNPTEPDHSIQWDRSMCVKNSTGVEIKRIMSKAFKSPLSAQQQSQLLAELEKDPKLVYHIGLSPVKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGEN 437

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Cavefish
Match: cnot11 (CCR4-NOT transcription complex subunit 11 [Source:NCBI gene;Acc:103041302])

HSP 1 Score: 258.455 bits (659), Expect = 2.986e-81
Identity = 161/441 (36.51%), Postives = 253/441 (57.37%), Query Frame = 1

Query:   22 KDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDI------KFGVGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGG 1302
            K++++LL + +E+    +FES+S  F+    K   F++G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF   V++ L++  +      K   G  P +    K FL+ +++     +EL KKTP QV     G   Q ID+S +   + + +++LPT  KA  P ++   D      DS   +G  S  +   IE L+ G  PP     RPEF R  PPL  +   +E+ W+NP   +H+      +  ++     I  ++  A  +PL   Q  QL  +L+++P L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G
Sbjct:    6 KELSNLLGIISEEACGNTFESLSNAFHHCFGKAEHFRVGSVLVMLLQQPDLLPSSPQRLTALYLLWEMYRTEPLAANPFAA-VFAHLLNPSVSGEEQEKPLSGFLPPITLPEKFFLSQLMLAPP--RELFKKTPRQVSCMDVGTAPQAIDISGLQLALAERQSELPTQSKASFPSLLSDPD-----PDS-SNSGFDSSVANQIIESLVTGPRPPLESHFRPEFIRPAPPL--LVCEDELAWLNPCEPEHRVQWDRSMCVRNGTGVEIKRIMAKAFKSPLSAAQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMSSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDNG 435

[Close]

Query:   22 KDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDI------KFGVGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGG 1302
            K++++LL + +E+    +FES+S  F+    K   F++G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF   V++ L++  +      K   G  P +    K FL+ +++     +EL KKTP QV     G   Q ID+S +   + + +++LPT  KA  P ++   D      DS   +G  S  +   IE L+ G  PP     RPEF R  PPL  +   +E+ W+NP   +H+      +  ++     I  ++  A  +PL   Q  QL  +L+++P L+  I   P++LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G
Sbjct:    6 KELSNLLGIISEEACGNTFESLSNAFHHCFGKAEHFRVGSVLVMLLQQPDLLPSSPQRLTALYLLWEMYRTEPLAANPFAA-VFAHLLNPSVSGEEQEKPLSGFLPPITLPEKFFLSQLMLAPP--RELFKKTPRQVSCMDVGTAPQAIDISGLQLALAERQSELPTQSKASFPSLLSDPD-----PDS-SNSGFDSSVANQIIESLVTGPRPPLESHFRPEFIRPAPPL--LVCEDELAWLNPCEPEHRVQWDRSMCVRNGTGVEIKRIMAKAFKSPLSAAQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMSSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDNG 435

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Sea Lamprey
Match: cnot11 (CCR4-NOT transcription complex, subunit 11 [Source:NCBI gene;Acc:336124])

HSP 1 Score: 249.21 bits (635), Expect = 2.328e-78
Identity = 164/452 (36.28%), Postives = 255/452 (56.42%), Query Frame = 1

Query:   16 TSKDINSLLNLFTEQNS-KQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPF-------IDLVYSSLISNDIKFGVGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQVYQEGNV---VQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSA---NGGSDG 1311
            ++K++++L+ L +E+ S K S ES+S      + +   F+ G AL+  L+  ++L    Q L A +LLWE+ + +    +PF       +D    S  ++ +    G  P +    K FL+ +++     +EL KKTP Q+         +Q +D+S +   + + +++LPT  KAG+P I       L  +D    +G  S  +    E LL G +PP    LRPEF R  PPLH     +E  WINP+  +H       +  Q +    I  L+  A  +PL  +Q  Q+  +L+++P L+  I   PS+LP LVE NP +A + LL L  + ++T YFS L+ M+++LHS+EVVN LT+AV+LP +FIH YI  CI +C +  DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+     G SDG
Sbjct:    4 SAKELSALIELVSEEASAKMSLESLSAALAHSVPRAQVFRAGAALLALLQQPDLLPGAPQRLAALYLLWEMYRTEPPAASPFAAVFAHLLDPASPSPTASAVAPAGGFLPPITGAEKFFLSHLMLAPP--RELFKKTPRQICATDMSTVPLQPVDISGLQLALAERQSELPTQSKAGIPAI-------LADADPDSGSGPDSTVAAQVAEALLTGTHPPIDSHLRPEFIRPVPPLHV--CEDEPAWINPTEPEHSVRWDRSMCVQSSAGLEIKRLMGKAFKSPLTVHQQKQVLNELEKDPKLVYHIGLTPSKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMEMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCENIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLECNEGPSDG 444

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Nematostella
Match: EDO46626 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPS5])

HSP 1 Score: 238.424 bits (607), Expect = 4.914e-74
Identity = 156/448 (34.82%), Postives = 262/448 (58.48%), Query Frame = 1

Query:   16 TSKDINSLLNLFTEQN-SKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSL------ISNDIKFGVGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV----YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCII--PFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSH----VDHQFMLGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGG 1302
            ++K++++LL++ +++  S  SFE+ ++  +    K   F+IG+AL++ L+  ++L++  Q L A FLL+E+ K++    NPF  +  + L       SN         P+L    K+F+  +I  T   KELLKKTP Q+    Y E  ++Q  D S++   + +  + LP I  +G P ++  P  D T+  S+S   T           E L+ G +PP+   L P + R+ PPL+     +E++W+NP+     ++    +   ++    +  L+  A   PL+  Q  Q+ ++++ +P L+  I   P++LP LVE NP +A + LL L+ + ++T YF+ L+ M+++LHS+EVVN LT+AV+LP +FIH YI  CI +C +  DKYM  RLVRLVCVFLQSLIRNK+ID+K++   +  FC++F+ I+EA  L++L+K+ + G
Sbjct:    4 STKELSALLSIVSDEAVSNVSFETTALALHQRFSKNEHFKIGSALLMLLQQPDLLSSSSQRLAALFLLYEMYKSEPIAANPFAQVFVNVLNPALDGDSNKAASETEKLPSLTIPEKSFIYELI--TNPSKELLKKTPQQILAIDYNE--MIQNFDTSNLQLSLTEKNSQLPEISCSGFPVVLADPHSDATMTSSNSIVIT-----------EALVTGCDPPSESVLLPSYTRVPPPLYSCD--DELVWMNPTSWVPSIEWDTTMCVTNSAGAEVRRLMAKAFKGPLLLQQQQQVLSEIENDPKLVYHIGLSPAKLPDLVENNPLVAIEVLLKLWQSNQITDYFTVLVNMEMSLHSMEVVNRLTNAVDLPQEFIHLYISNCISTCENLKDKYMQNRLVRLVCVFLQSLIRNKVIDVKDLFIEVQAFCIEFSRIREAAGLFRLLKTLDNG 434

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Medaka
Match: cnot11 (CCR4-NOT transcription complex subunit 11 [Source:NCBI gene;Acc:101162489])

HSP 1 Score: 256.914 bits (655), Expect = 1.017e-80
Identity = 163/445 (36.63%), Postives = 259/445 (58.20%), Query Frame = 1

Query:   22 KDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLI----SNDI--KFGVGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCII--PFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMH-RLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGGSD 1308
            K++++LL++ +++    SFE++S +F+    K + F++G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF   V++ L+    S D   K   G  P +    K FL+ +++     ++L KKTP QV      N+   ID+S +   + + +++LPT  KA  P I+  P  D++         +G  S  +   IE L+ G  PP     RPEF R  PPLH     +E+ W+NP+  DH       +  +++    I  ++  A  +PL   Q  QL A+L+++P L+  I   P +LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM  RLVRLVCVFLQSLIRNKII+++++   +  FC++F+ I+EA  L++L+K+ + G +
Sbjct:    6 KELSNLLSIISDEACNNSFETLSTHFHHYFGKADHFKVGSVLVMLLQQPDLLPSSPQRLTALYLLWEMYRTEPLAANPFAA-VFAHLLNPAPSGDEQEKALSGFLPPITQPEKFFLSQLMLAPP--RDLFKKTPRQVSCMDVSNMPPSIDISGLQLPLAERQSELPTQSKASFPSILNDPDPDSS--------NSGFDSSVANQIIESLVTGLRPPLESHFRPEFIRPTPPLH--TCEDELAWLNPTEPDHCIQWDRSMCVKNSTGVEIKRIMAKAFKSPLSAQQQSQLLAELEKDPKLVYHIGLTPVKLPELVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGEN 437

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Medaka
Match: cnot11 (CCR4-NOT transcription complex subunit 11 [Source:NCBI gene;Acc:101162489])

HSP 1 Score: 206.453 bits (524), Expect = 2.993e-61
Identity = 133/388 (34.28%), Postives = 213/388 (54.90%), Query Frame = 1

Query:   22 KDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDN-EPNPFIDLVYSSLISNDIKFG-------VGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQV--YQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCII--PFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFM----LGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYM 1137
            K++++LL++ +++    SFE++S +F+    K + F++G+ LV+ L+  ++L +  Q L A +LLWE+ + +    NPF   V++ L+ N    G        G  P +    K FL+ +++     ++L KKTP QV      N+   ID+S +   + + +++LPT  KA  P I+  P  D++         +G  S  +   IE L+ G  PP     RPEF R  PPLH     +E+ W+NP+  DH       +  +++    I  ++  A  +PL   Q  QL A+L+++P L+  I   P +LP LVE NP +A + LL L  + ++T YFS L+ MD++LHS+EVVN LT+AV+LP +FIH YI  CI +C    DKYM
Sbjct:    6 KELSNLLSIISDEACNNSFETLSTHFHHYFGKADHFKVGSVLVMLLQQPDLLPSSPQRLTALYLLWEMYRTEPLAANPFA-AVFAHLL-NPAPSGDEQEKALSGFLPPITQPEKFFLSQLMLAPP--RDLFKKTPRQVSCMDVSNMPPSIDISGLQLPLAERQSELPTQSKASFPSILNDPDPDSS--------NSGFDSSVANQIIESLVTGLRPPLESHFRPEFIRPTPPLHTC--EDELAWLNPTEPDHCIQWDRSMCVKNSTGVEIKRIMAKAFKSPLSAQQQSQLLAELEKDPKLVYHIGLTPVKLPELVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYM 379

[Close]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Planmine SMEST
Match: SMESG000081647.1 (SMESG000081647.1)

HSP 1 Score: 861.677 bits (2225), Expect = 0.000e+0
Identity = 435/435 (100.00%), Postives = 435/435 (100.00%), Query Frame = 1

Query:   10 MSTSKDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDNEPNPFIDLVYSSLISNDIKFGVGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQVYQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFMLGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMHRLVRLVCVFLQSLIRNKXXXXXXXXXXXLQFCLDFNSIKEANALYKLIKSANGGSDGD 1314
            MSTSKDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDNEPNPFIDLVYSSLISNDIKFGVGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQVYQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFMLGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMHRLVRLVCVFLQSLIRNKIIDIKEIQSIILQFCLDFNSIKEANALYKLIKSANGGSDGD
Sbjct:    1 MSTSKDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFLRSKEILNNQQQYLIAYFLLWELGKNDNEPNPFIDLVYSSLISNDIKFGVGDCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQVYQEGNVVQEIDLSSIHKIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIEGLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFMLGDQDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELPGLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAVELPTQFIHHYIERCIQSCHSSTDKYMHRLVRLVCVFLQSLIRNKIIDIKEIQSIILQFCLDFNSIKEANALYKLIKSANGGSDGD 435

The following BLAST results are available for this feature:

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Human
BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Celegans
BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Fly
BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Zebrafish
BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Xenopus
BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Mouse
BLAST of CCR4-NOT transcription complex, subunit 11 vs. UniProt/SwissProt
BLAST of CCR4-NOT transcription complex, subunit 11 vs. TrEMBL
BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Cavefish
BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Sea Lamprey
BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Yeast
BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Nematostella
BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Medaka
BLAST of CCR4-NOT transcription complex, subunit 11 vs. Planmine SMEST

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2


Match Name	E-value	Identity	Description
CNOT11	1.522e-80	36.47	CCR4-NOT transcription complex subunit 11 [Source:...	[more]
CNOT11	1.246e-28	46.15	CCR4-NOT transcription complex subunit 11 [Source:...	[more]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Not11	1.695e-50	46.64	gene:FBgn0034963 transcript:FBtr0072189	[more]
Not11	1.695e-50	46.64	gene:FBgn0034963 transcript:FBtr0343345	[more]
Not11	3.364e-46	42.39	gene:FBgn0034963 transcript:FBtr0072190	[more]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
cnot11	3.096e-77	36.14	CCR4-NOT transcription complex, subunit 11 [Source...	[more]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2


Match Name	E-value	Identity	Description
vwc2l.2	4.298e-80	36.40	von Willebrand factor C domain-containing protein ...	[more]
vwc2l.2	2.003e-77	36.38	von Willebrand factor C domain-containing protein ...	[more]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Cnot11	1.484e-80	36.69	CCR4-NOT transcription complex, subunit 11 [Source...	[more]
Cnot11	1.484e-80	36.69	CCR4-NOT transcription complex, subunit 11 [Source...	[more]
Cnot11	7.613e-39	54.20	CCR4-NOT transcription complex, subunit 11 [Source...	[more]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|B0BNA9\|CNO11_RAT	6.816e-80	36.69	CCR4-NOT transcription complex subunit 11 OS=Rattu...	[more]
sp\|Q9UKZ1\|CNO11_HUMAN	7.308e-80	36.47	CCR4-NOT transcription complex subunit 11 OS=Homo ...	[more]
sp\|Q9CWN7\|CNO11_MOUSE	1.038e-79	36.69	CCR4-NOT transcription complex subunit 11 OS=Mus m...	[more]
sp\|A4QP78\|CNO11_DANRE	2.337e-76	36.14	CCR4-NOT transcription complex subunit 11 OS=Danio...	[more]
sp\|Q1ZXI2\|CNO11_DICDI	1.209e-28	35.63	CCR4-NOT transcription complex subunit 11 OS=Dicty...	[more]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1I8GSL8	5.680e-89	39.05	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1I8JG42	6.033e-88	38.83	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A0L8H4C7	3.406e-86	38.94	Uncharacterized protein OS=Octopus bimaculoides OX...	[more]
A0A401P250	3.972e-83	36.88	Uncharacterized protein OS=Scyliorhinus torazame O...	[more]
A0A3P9CY27	4.826e-82	37.08	CCR4-NOT transcription complex, subunit 11 OS=Mayl...	[more]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
cnot11	2.986e-81	36.51	CCR4-NOT transcription complex subunit 11 [Source:...	[more]
cnot11	2.986e-81	36.51	CCR4-NOT transcription complex subunit 11 [Source:...	[more]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
cnot11	2.328e-78	36.28	CCR4-NOT transcription complex, subunit 11 [Source...	[more]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO46626	4.914e-74	34.82	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2


Match Name	E-value	Identity	Description
cnot11	1.017e-80	36.63	CCR4-NOT transcription complex subunit 11 [Source:...	[more]
cnot11	2.993e-61	34.28	CCR4-NOT transcription complex subunit 11 [Source:...	[more]

BLAST of CCR4-NOT transcription complex, subunit 11 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000081647.1	0.000e+0	100.00	SMESG000081647.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30003224 ID=SMED30003224|Name=CCR4-NOT transcription complex, subunit 11|organism=Schmidtea mediterranea sexual|type=transcript|length=1326bp
ATAATTTGAATGAGTACTAGTAAAGATATCAATAGTCTACTTAATTTATT
TACCGAACAAAATTCCAAACAATCTTTTGAATCTATTTCGGTAAATTTCA
ATATTATATTAGACAAAAGAAACTTCTTTCAAATTGGAACAGCTCTAGTA
TTATTTCTTCGGAGTAAAGAAATATTAAATAACCAACAACAATATCTTAT
TGCTTACTTTCTATTATGGGAATTGGGTAAAAATGACAATGAACCAAATC
CTTTTATAGATTTGGTTTATTCCTCATTAATTTCGAACGATATTAAATTC
GGCGTTGGTGATTGCCCAACTTTAGATTCGATTGGTAAAACTTTCCTTGC
ATCTGTTATAATACAAACTCAAAATTTTAAAGAGTTATTGAAAAAAACTC
CTAATCAAGTATACCAAGAAGGAAATGTTGTACAGGAAATAGATTTGAGC
AGTATACATAAAATTATGAATGATAACAAAACTGATTTGCCTACAATTTT
GAAAGCAGGCGTACCCTGTATTATTCCATTTGAAGATACAACTTTAATTA
AGAGTGATTCGTTTAAAGAAACTGGTAAAAGTTCTGAAGAAAGTAGAAGC
TCTATTGAAGGATTGCTCCTAGGAGATAATCCACCTGCATATAGATCTTT
AAGACCCGAATTTAAGCGATTACAACCTCCTCTACATTGTATTGGAACAT
ATAATGAAATGATTTGGATCAATCCATCGCATGTTGATCATCAATTTATG
CTCGGAGATCAGGATAACAATGAAGAATATATTATTGGTTTATTAAAATC
TGCTAAAACGACTCCTTTGATGCAAAATCAAATTATTCAACTGCAGGCTA
AATTAAAAGAAAATCCCGATTTATTGAAAAAAATTGATTTCAAACCCTCA
GAATTACCTGGTCTTGTAGAAAAGAATCCTGCAATTGCAAATGATGCTCT
TTTGATTTTGTTTGACACTCAAGAAGTAACTAGTTATTTTTCTGAACTTA
TTAAAATGGACATAACGTTACATTCATTGGAAGTAGTTAATCTTTTGACT
AGTGCAGTTGAATTGCCAACCCAATTCATCCATCATTATATTGAAAGATG
CATTCAATCATGCCACAGCTCCACGGATAAATATATGCATCGACTAGTTA
GACTCGTTTGTGTATTTTTACAATCTCTCATTAGAAACAAGATTATTGAC
ATAAAGGAAATTCAAAGTATAATTTTACAATTCTGTTTGGATTTTAATAG
CATAAAAGAAGCCAATGCATTATATAAATTAATAAAATCAGCTAATGGTG
GTTCAGATGGTGATTAAAATTTTTAT

protein sequence of SMED30003224-orf-1

>SMED30003224-orf-1 ID=SMED30003224-orf-1|Name=SMED30003224-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=436bp
MSTSKDINSLLNLFTEQNSKQSFESISVNFNIILDKRNFFQIGTALVLFL
RSKEILNNQQQYLIAYFLLWELGKNDNEPNPFIDLVYSSLISNDIKFGVG
DCPTLDSIGKTFLASVIIQTQNFKELLKKTPNQVYQEGNVVQEIDLSSIH
KIMNDNKTDLPTILKAGVPCIIPFEDTTLIKSDSFKETGKSSEESRSSIE
GLLLGDNPPAYRSLRPEFKRLQPPLHCIGTYNEMIWINPSHVDHQFMLGD
QDNNEEYIIGLLKSAKTTPLMQNQIIQLQAKLKENPDLLKKIDFKPSELP
GLVEKNPAIANDALLILFDTQEVTSYFSELIKMDITLHSLEVVNLLTSAV
ELPTQFIHHYIERCIQSCHSSTDKYMHRLVRLVCVFLQSLIRNKIIDIKE
IQSIILQFCLDFNSIKEANALYKLIKSANGGSDGD*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR030395	GP_PDE_dom
IPR019312	CNOT11

Vocabulary: **biological process**
Term	Definition
GO:0006629	lipid metabolic process
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006417	regulation of translation
GO:0031047	gene silencing by RNA

Vocabulary: **molecular function**
Term	Definition
GO:0008081	phosphoric diester hydrolase activity

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0030014	CCR4-NOT complex

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR019312	CCR4-NOT transcription complex subunit 11	PFAM	PF10155	CNOT11	coord: 303..426 e-value: 5.8E-41 score: 139.6
IPR019312	CCR4-NOT transcription complex subunit 11	PANTHER	PTHR15975	UNCHARACTERIZED	coord: 1..429
None	No IPR available	PANTHER	PTHR15975:SF0	CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11	coord: 1..429

Main menu

CCR4-NOT transcription complex, subunit 11

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Owlery

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