Adenylosuccinate synthetase

Overview
NameAdenylosuccinate synthetase
Smed IDSMED30003172
Length (bp)1555
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Adenylosuccinate synthetase (SMED30003172) t-SNE clustered cells

Violin plots show distribution of expression levels for Adenylosuccinate synthetase (SMED30003172) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Adenylosuccinate synthetase (SMED30003172) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Adenylosuccinate synthetase (SMED30003172) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30003172

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 15

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30003172SMESG000078697.1 dd_Smed_v4_2154_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30003172SMESG000078697.1 dd_Smed_v4_2154_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003172SMESG000078697.1 dd_Smed_v4_2154_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30003172SMESG000078697.1 dd_Smed_v4_2154_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003172SMESG000078697.1 dd_Smed_v4_2154_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30003172SMESG000078697.1 dd_Smed_v4_2154_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30003172SMESG000078697.1 dd_Smed_v4_2154_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30003172SMESG000078697.1 Contig49854newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30003172SMESG000078697.1 Contig49854uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30003172SMESG000078697.1 SMED30003172smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30003172SMESG000078697.1 SMED30003172smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
Category 3 cellSMED30003172SMESG000078697.1 dd_Smed_v6_2154_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003172SMESG000078697.1 dd_Smed_v4_2154_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
neoblastSMED30003172SMESG000078697.1 SMED_20382_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30003172SMESG000078697.1 SMED_20382_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Adenylosuccinate synthetase vs. Ensembl Human
Match: ADSS2 (adenylosuccinate synthase 2 [Source:HGNC Symbol;Acc:HGNC:292])

HSP 1 Score: 475.322 bits (1222), Expect = 2.027e-164
Identity = 243/428 (56.78%), Postives = 313/428 (73.13%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEI--NVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKR---GGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            + V V +GAQWGDEGKGK+VDL AQ+ D+VCRCQGGNNAGHTV+ ++V+YDFHLLPSGI+   +TA IGNGVVI+L  L  E   NV   KGL   ++RLIISDRAHIVFD HQ  DG+QE++R    G  +GTTKKGIGP YSSKA R+GLR+CDL+ D+  F E++K L +   + Y  ++ID++ +L++L  Y +++ PMV++ + +L E L     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP+++  V+GV+KAYTTRVG+G FPTE  +EIGE  Q  G E GVTT RKRR GWLD V+L+YAHMINGF A+ LTKLD+LD   E+KVG  Y  K  GEII   PAN ++L  ++V+Y+ LPGW     N R F +LP  AQ +V  +E  + IP++WIGVG  R  +I
Sbjct:   28 NRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLEGWEKRLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFDGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAY--KLDGEIIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKELPVNAQNYVRFIEDELQIPVKWIGVGKSRESMI 453
[Close]
BLAST of Adenylosuccinate synthetase vs. Ensembl Human
Match: ADSS1 (adenylosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:20093])

HSP 1 Score: 470.315 bits (1209), Expect = 1.989e-162
Identity = 240/426 (56.34%), Postives = 308/426 (72.30%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRG---GSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            S V V +GAQWGDEGKGK+VDL A + D++ RCQGGNNAGHTV+ +  +YDFHLLPSGI+     + IGNGVVI+L  L  E   N KKGL D ++RLIISDRAH+VFD HQ +DGLQE +R    G  IGTTKKGIGPTYSSKA R GLRICDL+ D+  F  ++K L     + +  ++ID++  L+ L  + + + PMV++ + ++ E L     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP++I  V+GV+KAYTTRVG+G FPTE  +EIG   Q  GHE GVTT RKRR GWLD ++LRYAHM+NGF A+ LTKLD+LD L EVKVG  Y  K +G+ I  FPAN ++L+ ++VEYE LPGWK  T   R + DLP +AQ ++  VE  +G+ ++W+GVG  R  +I
Sbjct:   31 SRVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSDFDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLGEVKVGVSY--KLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYIRFVENHVGVAVKWVGVGKSRESMI 454
[Close]
BLAST of Adenylosuccinate synthetase vs. Ensembl Human
Match: ADSS1 (adenylosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:20093])

HSP 1 Score: 421.779 bits (1083), Expect = 8.115e-143
Identity = 218/393 (55.47%), Postives = 282/393 (71.76%), Query Frame = 1 
Query:  229 QGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRG---GSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            +GGNNAGHTV+ +  +YDFHLLPSGI+     + IGNGVVI+L  L  E   N KKGL D ++RLIISDRAH+VFD HQ +DGLQE +R    G  IGTTKKGIGPTYSSKA R GLRICDL+ D+  F  ++K L     + +  ++ID++  L+ L  + + + PMV++ + ++ E L     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP++I  V+GV+KAYTTRVG+G FPTE  +EIG   Q  GHE GVTT RKRR GWLD ++LRYAHM+NGF A+ LTKLD+LD L EVKVG  Y  K +G+ I  FPAN ++L+ ++VEYE LPGWK  T   R + DLP +AQ ++  VE  +G+ ++W+GVG  R  +I
Sbjct:  107 RGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSDFDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLGEVKVGVSY--KLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYIRFVENHVGVAVKWVGVGKSRESMI 497
[Close]
BLAST of Adenylosuccinate synthetase vs. Ensembl Human
Match: ADSS1 (adenylosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:20093])

HSP 1 Score: 93.5893 bits (231), Expect = 4.205e-21
Identity = 44/73 (60.27%), Postives = 54/73 (73.97%), Query Frame = 1 
Query:  229 QGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHI 447
            +GGNNAGHTV+ +  +YDFHLLPSGI+     + IGNGVVI+L  L  E   N KKGL D ++RLIISDRAH+
Sbjct:  107 RGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRLIISDRAHL 179
[Close]
BLAST of Adenylosuccinate synthetase vs. Ensembl Human
Match: ADSS1 (adenylosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:20093])

HSP 1 Score: 68.1662 bits (165), Expect = 5.819e-14
Identity = 26/60 (43.33%), Postives = 40/60 (66.67%), Query Frame = 1 
Query: 1219 ILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            +L+ ++VEYE LPGWK  T   R + DLP +AQ ++  VE  +G+ ++W+GVG  R  +I
Sbjct:    1 MLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYIRFVENHVGVAVKWVGVGKSRESMI 60
[Close]
BLAST of Adenylosuccinate synthetase vs. Ensembl Celegans
Match: adss-1 (Adenylosuccinate synthetase [Source:UniProtKB/Swiss-Prot;Acc:P91134])

HSP 1 Score: 398.282 bits (1022), Expect = 6.344e-135
Identity = 206/428 (48.13%), Postives = 295/428 (68.93%), Query Frame = 1 
Query:  136 VIVFIGAQWGDEGKGKLVDLFAQ--ECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGG-SMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPM--VKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDIIYR 1404
            V V +GAQWGDEGKGK++D   +  + +V  RCQGGNNAGHTV+AN  KYDFH+LPSGI+      VIGNGVV+NL    +E+  N     S  ++R++IS  AH+VF +H  +DG QE+     + IGTT +GIGPTYSSK  RNG+R+ DL+ D+  F EKY++LV +   ++  ++++V ++L +   +R++L+ +  V +T+ +++E+  +GK ++LVEGA   +LDIDFG+YPYVTSSN  VGG CTG+G+PP ++ +V GV+KAY TRVG G FPTELFD  GE  Q +G E+GVTT RKRR GW+D  +LR + MING+ A+ LTKLD+LD    +KV   Y  K +G+++ + PA  +    I+VEY+   GW + T   R+F DLP++ + +V+ +E  I +PI +IGVGA+R  +I R
Sbjct:    8 VSVLLGAQWGDEGKGKIIDYLIENHKINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFSELAHNGILEESGWEKRIMISSEAHLVFGVHSQVDGRQEDSLAAKNKIGTTNRGIGPTYSSKCFRNGIRVADLMADFEEFSEKYRRLVEHYKKQFPSIEVNVDEELAKFKQHREKLAELKLVGDTVGFIHEQRNAGK-QVLVEGANGALLDIDFGTYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLRRSAMINGYTAIALTKLDILDTFPTIKVAVGY--KLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEKCRQYVKFIEDFIKVPIVYIGVGAERESLIVR 432
[Close]
BLAST of Adenylosuccinate synthetase vs. Ensembl Celegans
Match: adss-1 (Adenylosuccinate synthetase [Source:UniProtKB/Swiss-Prot;Acc:P91134])

HSP 1 Score: 398.667 bits (1023), Expect = 7.859e-135
Identity = 206/428 (48.13%), Postives = 295/428 (68.93%), Query Frame = 1 
Query:  136 VIVFIGAQWGDEGKGKLVDLFAQ--ECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGG-SMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPM--VKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDIIYR 1404
            V V +GAQWGDEGKGK++D   +  + +V  RCQGGNNAGHTV+AN  KYDFH+LPSGI+      VIGNGVV+NL    +E+  N     S  ++R++IS  AH+VF +H  +DG QE+     + IGTT +GIGPTYSSK  RNG+R+ DL+ D+  F EKY++LV +   ++  ++++V ++L +   +R++L+ +  V +T+ +++E+  +GK ++LVEGA   +LDIDFG+YPYVTSSN  VGG CTG+G+PP ++ +V GV+KAY TRVG G FPTELFD  GE  Q +G E+GVTT RKRR GW+D  +LR + MING+ A+ LTKLD+LD    +KV   Y  K +G+++ + PA  +    I+VEY+   GW + T   R+F DLP++ + +V+ +E  I +PI +IGVGA+R  +I R
Sbjct:   31 VSVLLGAQWGDEGKGKIIDYLIENHKINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFSELAHNGILEESGWEKRIMISSEAHLVFGVHSQVDGRQEDSLAAKNKIGTTNRGIGPTYSSKCFRNGIRVADLMADFEEFSEKYRRLVEHYKKQFPSIEVNVDEELAKFKQHREKLAELKLVGDTVGFIHEQRNAGK-QVLVEGANGALLDIDFGTYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLRRSAMINGYTAIALTKLDILDTFPTIKVAVGY--KLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEKCRQYVKFIEDFIKVPIVYIGVGAERESLIVR 455
[Close]
BLAST of Adenylosuccinate synthetase vs. Ensembl Fly
Match: AdSS (gene:FBgn0027493 transcript:FBtr0083991)

HSP 1 Score: 472.626 bits (1215), Expect = 7.253e-164
Identity = 235/423 (55.56%), Postives = 313/423 (74.00%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            S+V V +GAQWGDEGKGK+VD+ A + D+VCRCQGGNNAGHTV+AN  ++DFHLLPSG++ +   +VIGNGVVI+L  L +E+  N  KGL  ++ RLIISDRAH+VFD HQ +DG+QE ++GG  +GTTKKGIGP YSSKATRNG+R+ +L+GD+ LF EK+K +V+     +  + +DV+ +L     Y  ++ P VK+TI +L+  L++GK+ ILVEGA + MLDIDFG+YPYVTSSNC +GGV TGLGLPP++I  V GV+KAYTTRVG G FPTE  ++IG+  Q  G E+GVTT+RKRR GWLD  +L+Y  ++NG+  + LTKLD+LD L E+KV   Y  K +GE +  FP  +  L NI+VEY VLPGW+ ST+  R F +LP+ AQ +V  +E  + +P+RW+GVG  R  II
Sbjct:   24 SKVDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDEVLKNEAKGLQHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLGDFNLFSEKFKSIVATHVRLFPSINVDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKT-ILVEGANAAMLDIDFGTYPYVTSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNGYTCICLTKLDILDTLPEIKVAVAY-KKPNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVRFLESELSVPVRWVGVGKGRESII 444
[Close]
BLAST of Adenylosuccinate synthetase vs. Ensembl Zebrafish
Match: adss2 (adenylosuccinate synthase 2 [Source:NCBI gene;Acc:550502])

HSP 1 Score: 481.485 bits (1238), Expect = 3.672e-167
Identity = 244/428 (57.01%), Postives = 315/428 (73.60%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEI--NVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKR---GGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            + V V +GAQWGDEGKGK+VDL AQ+ D+VCRCQGGNNAGHTV+ ++V+YDFHLLPSGI+   +TA IGNGVVI+L  L  E   NV   KGL   + RLIISDRAHIVFD HQ +DG+QE++R    G  +GTTKKGIGP YS+KA R+GLRICDL+ D+  F E++K L S   + Y  ++IDV  +LE+L  Y   + PMV++ + ++ E L     +ILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP+++  V+GV+KAYTTRVG+G FPTE  +E GE  Q  G E+GVTT RKRR GWLD V+++YAHMINGF A+ LTKLD+LD L E+KVG  Y  K +GE I  FPAN ++L+ ++VEYE LPGW   T   R F +LP+ A+ +V  +E  +G+P++WIGVG  R  +I
Sbjct:   27 NRVTVVLGAQWGDEGKGKVVDLLAQDADMVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPKVTAFIGNGVVIHLPGLFEEAEKNVRKGKGLEGWESRLIISDRAHIVFDFHQAVDGVQEQERQQQAGKNLGTTKKGIGPVYSAKAARSGLRICDLLADFQEFSERFKHLASQYKSMYPSLEIDVDGELEKLKSYVDRIKPMVRDGVFFMYEALHGDPKRILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQSNETGELLQTRGKEVGVTTGRKRRCGWLDLVLIKYAHMINGFTALALTKLDILDVLPEIKVGVAY--KVNGETIPHFPANQEVLQKVEVEYETLPGWSTDTSAVRTFEELPENAKKYVCFIEDRLGVPVKWIGVGKSRESMI 452
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BLAST of Adenylosuccinate synthetase vs. Ensembl Zebrafish
Match: adss1 (adenylosuccinate synthase 1 [Source:NCBI gene;Acc:407989])

HSP 1 Score: 479.559 bits (1233), Expect = 2.914e-166
Identity = 243/426 (57.04%), Postives = 315/426 (73.94%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRG---GSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            ++V V +GAQWGDEGKGK+VDL A E D+V RCQGGNNAGHTV+    +YDFHLLPSGI+    T+ IGNGVVI+L  L  EI+ N KKGL   ++RL+ISDRAHIVFD HQ +DGLQE +R    G  IGTTKKGIGPTY+ KA+R GLRICDL+ D+  F  + K LV    + Y  +K+DV+ +L++L  Y + + P+V++ + ++ + +   + KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP +I  V+GV KAYTTRVG+G FPTE  + +GE  Q  GHE+GVTT RKRR GWLD V+L+YAHMINGF A+ LTKLD+LD LDE+KVG  Y  K +G+ I  FPAN+++L+ ++VEYE  PGWK  T   R++ DLP +AQ ++  VE  IG+PI+W+GVG  R  +I
Sbjct:   30 NKVTVVLGAQWGDEGKGKVVDLLATESDIVGRCQGGNNAGHTVVVEEKEYDFHLLPSGIINTKCTSFIGNGVVIHLPGLFEEIDKNEKKGLKGWEKRLVISDRAHIVFDFHQAVDGLQETQRQAQEGKNIGTTKKGIGPTYACKASRTGLRICDLMADFNEFSTRVKNLVQQYQSMYPTLKVDVESELKKLKEYAERIRPLVRDGVYFMYDAIHGPQKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPANIGDVYGVSKAYTTRVGIGAFPTEQLNAVGELLQTRGHEVGVTTGRKRRCGWLDLVILKYAHMINGFTAIALTKLDILDVLDEIKVGVAY--KINGKRIPHFPANLEVLQKVEVEYETFPGWKSDTSAARKWGDLPAKAQNYIRFVENHIGVPIKWVGVGKSRECMI 453
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BLAST of Adenylosuccinate synthetase vs. Ensembl Zebrafish
Match: adssl (adenylosuccinate synthase, like [Source:ZFIN;Acc:ZDB-GENE-020419-28])

HSP 1 Score: 478.019 bits (1229), Expect = 1.831e-165
Identity = 233/428 (54.44%), Postives = 314/428 (73.36%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKG--LSDIKQRLIISDRAHIVFDLHQMIDGLQEEKR---GGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            ++V V +GAQWGDEGKGK+VDL A + D+VCRCQGGNNAGHTV+ ++V+YDFHLLPSG+L K  T+ IGNGVVI+L  L +E   N++KG  L   ++RL ISDRAHIVF+ HQ +DG+QE+ R    G  +GTTKKGIGP YSSKA RNGLR+CDL+ D+ +FEEK++ L  +    Y ++ ID+  +L++L  + + L P+V + + ++++ L     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP  +  V+GV+KAYTTRVGVG FPTE  +EIG+  Q  G E GVTT R+RR GWLD V++RYAHM+NGF A+ LTKLD+LD L E+K+G  Y     G+ + +FPANMD+L  + V YE  PGW  ST+  R F +LP +AQ +++ +E  + +P++W+GVG  R  +I
Sbjct:   40 NKVTVVLGAQWGDEGKGKVVDLLAMDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGVLNKKATSFIGNGVVIHLPGLFDEAEKNLQKGNGLQGWEERLKISDRAHIVFNFHQAVDGIQEQLRQQQAGKNLGTTKKGIGPAYSSKAARNGLRVCDLVSDFSVFEEKFRVLAGHYQTTYPNLNIDIDAELQQLKNFAERLRPLVTDGVYFMHKALTGPSKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGVPPSHVGRVYGVVKAYTTRVGVGAFPTEQNNEIGDLLQSRGREFGVTTGRRRRCGWLDLVLVRYAHMVNGFSAIALTKLDILDTLPEIKIGTAYT--VDGKPLPSFPANMDVLTKVQVTYETFPGWSCSTEGVRSFDELPTQAQSYIKFIEDFLQVPVKWVGVGKSRESMI 465
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BLAST of Adenylosuccinate synthetase vs. Ensembl Xenopus
Match: il17c (interleukin 17C [Source:Xenbase;Acc:XB-GENE-959427])

HSP 1 Score: 476.093 bits (1224), Expect = 9.533e-165
Identity = 245/428 (57.24%), Postives = 312/428 (72.90%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKG--LSDIKQRLIISDRAHIVFDLHQMIDGLQEEKR---GGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            ++V V +GAQWGDEGKGK+VDL AQ+ D+VCRCQGGNNAGHTV+ ++V+YDFHLLPSGI+ +   A IGNGVVI+L  L  E   N+KKG  L   ++RL ISDRAHIVFD HQ  DG+QE++R    G  +GTTKKGIGP YSSKA R+GLR+CDL+ D+  F +++K L     + Y  ++ID+  +L++L  Y   + PMVK+ + +L E L      ILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP+S+  V+GV+KAYTTRVG+G FPTE  ++ GE  Q  GHE GVTT RKRR GWLD V+LRYAHMINGF A+ LTKLD+LD L E+KVG  Y  K  G+ I  FPAN ++L  ++VEYE LPGW   T N R F +LP+ A+ +V  +E  +GIPI+WIGVG  R  +I
Sbjct:   33 NKVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINQNAIAFIGNGVVIHLPGLFEEAEKNLKKGQGLVGWEKRLCISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFSEFSQRFKLLAKQYKSMYPSLEIDIDGELKKLQDYADRVKPMVKDGVYYLYEALHGPPKNILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQSVGDVYGVVKAYTTRVGIGAFPTEQNNDTGEMLQTRGHEYGVTTGRKRRCGWLDLVLLRYAHMINGFTALALTKLDILDVLSEIKVGVSY--KIDGKKIPHFPANQEVLNRVEVEYETLPGWNTDTCNVRTFEELPENAKKYVRYIELELGIPIKWIGVGKSRESMI 458
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BLAST of Adenylosuccinate synthetase vs. Ensembl Xenopus
Match: ppp2r2d (protein phosphatase 2 regulatory subunit B, delta [Source:Xenbase;Acc:XB-GENE-940312])

HSP 1 Score: 475.707 bits (1223), Expect = 9.836e-165
Identity = 240/426 (56.34%), Postives = 313/426 (73.47%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRG---GSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            ++V V +GAQWGDEGKGK+VDL A + D++CRCQGGNNAGHTV+    +YDFHL PSGI+     + IGNGVVI+L  L  E + N KKGL D ++RLIISDRAHIV D HQ +DGLQE +R    G  IGTTKKGIGPTYSSKA+R GLRICDL+ D+  F  ++K L     + + ++++D+   L++L +Y +++ PMV++ + ++ E L     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP++I  V+GV+K Y+TRVG+G FPTE  +EIG   Q  GHE GVTT RKRR GWLD V+LRYAHMINGF A+ LTKLD+LD LDE+KVG  Y  + +G+ I  FPAN +IL+ ++VEYE +PGWK  T   R++ DLP  AQ ++  VE  IG+P++W+GVG  R  +I
Sbjct:   21 NKVTVVLGAQWGDEGKGKVVDLLATDSDIICRCQGGNNAGHTVVVEGKEYDFHLFPSGIINPKAISFIGNGVVIHLPGLFEEADKNEKKGLKDWEKRLIISDRAHIVCDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKASRTGLRICDLLSDFDEFSARFKNLAHQHQSMFSNLEVDIDGQLKKLKMYAEKIRPMVRDGVYFMYEALHGSPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKTYSTRVGIGAFPTEQINEIGNLLQTRGHEWGVTTGRKRRCGWLDLVILRYAHMINGFTALALTKLDILDVLDEIKVGVAY--RLNGKRIPYFPANQEILQKVEVEYEAMPGWKCDTTGARKWEDLPTRAQNYIRFVENHIGVPVKWVGVGKSRESMI 444
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BLAST of Adenylosuccinate synthetase vs. Ensembl Xenopus
Match: il17c (interleukin 17C [Source:Xenbase;Acc:XB-GENE-959427])

HSP 1 Score: 475.707 bits (1223), Expect = 2.435e-164
Identity = 245/428 (57.24%), Postives = 312/428 (72.90%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKG--LSDIKQRLIISDRAHIVFDLHQMIDGLQEEKR---GGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            ++V V +GAQWGDEGKGK+VDL AQ+ D+VCRCQGGNNAGHTV+ ++V+YDFHLLPSGI+ +   A IGNGVVI+L  L  E   N+KKG  L   ++RL ISDRAHIVFD HQ  DG+QE++R    G  +GTTKKGIGP YSSKA R+GLR+CDL+ D+  F +++K L     + Y  ++ID+  +L++L  Y   + PMVK+ + +L E L      ILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP+S+  V+GV+KAYTTRVG+G FPTE  ++ GE  Q  GHE GVTT RKRR GWLD V+LRYAHMINGF A+ LTKLD+LD L E+KVG  Y  K  G+ I  FPAN ++L  ++VEYE LPGW   T N R F +LP+ A+ +V  +E  +GIPI+WIGVG  R  +I
Sbjct:   49 NKVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINQNAIAFIGNGVVIHLPGLFEEAEKNLKKGQGLVGWEKRLCISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFSEFSQRFKLLAKQYKSMYPSLEIDIDGELKKLQDYADRVKPMVKDGVYYLYEALHGPPKNILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQSVGDVYGVVKAYTTRVGIGAFPTEQNNDTGEMLQTRGHEYGVTTGRKRRCGWLDLVLLRYAHMINGFTALALTKLDILDVLSEIKVGVSY--KIDGKKIPHFPANQEVLNRVEVEYETLPGWNTDTCNVRTFEELPENAKKYVRYIELELGIPIKWIGVGKSRESMI 474
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BLAST of Adenylosuccinate synthetase vs. Ensembl Xenopus
Match: ppp2r2d (protein phosphatase 2 regulatory subunit B, delta [Source:Xenbase;Acc:XB-GENE-940312])

HSP 1 Score: 464.922 bits (1195), Expect = 3.632e-160
Identity = 240/442 (54.30%), Postives = 313/442 (70.81%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHI----------------VFDLHQMIDGLQEEKRG---GSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            ++V V +GAQWGDEGKGK+VDL A + D++CRCQGGNNAGHTV+    +YDFHL PSGI+     + IGNGVVI+L  L  E + N KKGL D ++RLIISDRAHI                V D HQ +DGLQE +R    G  IGTTKKGIGPTYSSKA+R GLRICDL+ D+  F  ++K L     + + ++++D+   L++L +Y +++ PMV++ + ++ E L     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP++I  V+GV+K Y+TRVG+G FPTE  +EIG   Q  GHE GVTT RKRR GWLD V+LRYAHMINGF A+ LTKLD+LD LDE+KVG  Y  + +G+ I  FPAN +IL+ ++VEYE +PGWK  T   R++ DLP  AQ ++  VE  IG+P++W+GVG  R  +I
Sbjct:   26 NKVTVVLGAQWGDEGKGKVVDLLATDSDIICRCQGGNNAGHTVVVEGKEYDFHLFPSGIINPKAISFIGNGVVIHLPGLFEEADKNEKKGLKDWEKRLIISDRAHIGKPLSFCVSLFLLYYLVCDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKASRTGLRICDLLSDFDEFSARFKNLAHQHQSMFSNLEVDIDGQLKKLKMYAEKIRPMVRDGVYFMYEALHGSPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKTYSTRVGIGAFPTEQINEIGNLLQTRGHEWGVTTGRKRRCGWLDLVILRYAHMINGFTALALTKLDILDVLDEIKVGVAY--RLNGKRIPYFPANQEILQKVEVEYEAMPGWKCDTTGARKWEDLPTRAQNYIRFVENHIGVPVKWVGVGKSRESMI 465
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BLAST of Adenylosuccinate synthetase vs. Ensembl Xenopus
Match: il17c (interleukin 17C [Source:Xenbase;Acc:XB-GENE-959427])

HSP 1 Score: 456.062 bits (1172), Expect = 3.482e-157
Identity = 235/426 (55.16%), Postives = 302/426 (70.89%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKR---GGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            ++V V +GAQWGDEGKGK+VDL AQ+ D+VCRCQGGNNAGHTV+ ++V+YDFHLLPSGI+ +   A IGNGVVI+L  L  E   N+KKG            + H +FD HQ  DG+QE++R    G  +GTTKKGIGP YSSKA R+GLR+CDL+ D+  F +++K L     + Y  ++ID+  +L++L  Y   + PMVK+ + +L E L      ILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP+S+  V+GV+KAYTTRVG+G FPTE  ++ GE  Q  GHE GVTT RKRR GWLD V+LRYAHMINGF A+ LTKLD+LD L E+KVG  Y  K  G+ I  FPAN ++L  ++VEYE LPGW   T N R F +LP+ A+ +V  +E  +GIPI+WIGVG  R  +I
Sbjct:   29 NKVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINQNAIAFIGNGVVIHLPGLFEEAEKNLKKG------------QEHNLFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFSEFSQRFKLLAKQYKSMYPSLEIDIDGELKKLQDYADRVKPMVKDGVYYLYEALHGPPKNILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQSVGDVYGVVKAYTTRVGIGAFPTEQNNDTGEMLQTRGHEYGVTTGRKRRCGWLDLVLLRYAHMINGFTALALTKLDILDVLSEIKVGVSY--KIDGKKIPHFPANQEVLNRVEVEYETLPGWNTDTCNVRTFEELPENAKKYVRYIELELGIPIKWIGVGKSRESMI 440
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BLAST of Adenylosuccinate synthetase vs. Ensembl Mouse
Match: Adss (adenylosuccinate synthetase, non muscle [Source:MGI Symbol;Acc:MGI:87948])

HSP 1 Score: 476.093 bits (1224), Expect = 6.709e-165
Identity = 244/428 (57.01%), Postives = 311/428 (72.66%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEI--NVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKR---GGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            + V V +GAQWGDEGKGK+VDL AQ+ D+VCRCQGGNNAGHTV+ ++V+YDFHLLPSGI+   +TA IGNGVVI+L  L  E   NV   KGL   ++RLIISDRAHIVFD HQ  DG+QE++R    G  +GTTKKGIGP YSSKA R+GLR+CDL+ D+  F E++K L +   + Y  ++ID++ +L++L  Y + + PMVK+ + +L E L     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP+++  V+GV+KAYTTRVG+G FPTE  +EIGE  Q  G E GVTT RKRR GWLD V L+YAHMINGF A+ LTKLD+LD   E+KVG  Y  K  GE I  FPAN ++L  ++V+Y+ LPGW     N R F +LP  AQ +V  +E  + IP++WIGVG  R  +I
Sbjct:   28 NRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLDGWEKRLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFDGFSERFKVLANQYKSIYPTLEIDIEGELQQLKGYMERIKPMVKDGVYFLYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSLKYAHMINGFTALALTKLDILDMFTEIKVGVAY--KLDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVNAQNYVRFIEDELQIPVKWIGVGKSRESMI 453
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BLAST of Adenylosuccinate synthetase vs. Ensembl Mouse
Match: Adssl1 (adenylosuccinate synthetase like 1 [Source:MGI Symbol;Acc:MGI:87947])

HSP 1 Score: 472.626 bits (1215), Expect = 1.285e-163
Identity = 242/426 (56.81%), Postives = 310/426 (72.77%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRG---GSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            S V V +GAQWGDEGKGK+VDL A + D+V RCQGGNNAGHTV+ +  +YDFHLLPSGI+     + IGNGVVI+L  L  E   N KKGL D ++RLIISDRAH+VFD HQ +DGLQE +R    G  IGTTKKGIGPTYSSKA R GLRICDL+ D+  F  ++K L     + +  ++IDV+  L+ L  + + + PMV++ + ++ E L     K+LVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP++I  V+GV+KAYTTRVG+G FPTE  +EIG+  Q  GHE GVTT RKRR GWLD ++LRYAHM+NGF A+ LTKLD+LD L E+KVG  Y  K +G+ I  FPAN +IL+ ++VEYE LPGWK  T   R++ DLP +AQ +V  VE  +G+ ++W+GVG  R  +I
Sbjct:   31 SRVTVVLGAQWGDEGKGKVVDLLATDADIVSRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSDFDEFSARFKNLAHQHQSMFPTLEIDVEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKVLVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGDLLQNRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLSEIKVGISY--KLNGKRIPYFPANQEILQKVEVEYETLPGWKADTTGARKWEDLPPQAQSYVRFVENHMGVAVKWVGVGKSRESMI 454
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BLAST of Adenylosuccinate synthetase vs. Ensembl Mouse
Match: Adssl1 (adenylosuccinate synthetase like 1 [Source:MGI Symbol;Acc:MGI:87947])

HSP 1 Score: 459.144 bits (1180), Expect = 5.765e-158
Identity = 242/449 (53.90%), Postives = 310/449 (69.04%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHI-----------------------VFDLHQMIDGLQEEKRG---GSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            S V V +GAQWGDEGKGK+VDL A + D+V RCQGGNNAGHTV+ +  +YDFHLLPSGI+     + IGNGVVI+L  L  E   N KKGL D ++RLIISDRAH+                       VFD HQ +DGLQE +R    G  IGTTKKGIGPTYSSKA R GLRICDL+ D+  F  ++K L     + +  ++IDV+  L+ L  + + + PMV++ + ++ E L     K+LVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP++I  V+GV+KAYTTRVG+G FPTE  +EIG+  Q  GHE GVTT RKRR GWLD ++LRYAHM+NGF A+ LTKLD+LD L E+KVG  Y  K +G+ I  FPAN +IL+ ++VEYE LPGWK  T   R++ DLP +AQ +V  VE  +G+ ++W+GVG  R  +I
Sbjct:   31 SRVTVVLGAQWGDEGKGKVVDLLATDADIVSRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRLIISDRAHLENEVPHKPLPSASLLPMCWLLAPVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSDFDEFSARFKNLAHQHQSMFPTLEIDVEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKVLVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGDLLQNRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLSEIKVGISY--KLNGKRIPYFPANQEILQKVEVEYETLPGWKADTTGARKWEDLPPQAQSYVRFVENHMGVAVKWVGVGKSRESMI 477
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BLAST of Adenylosuccinate synthetase vs. UniProt/SwissProt
Match: sp|Q5D8V5|PURA_SCHJA (Adenylosuccinate synthetase OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 522.702 bits (1345), Expect = 0.000e+0
Identity = 264/425 (62.12%), Postives = 329/425 (77.41%), Query Frame = 1 
Query:  136 VIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDIIYRSV 1410
            V V +GAQWGDEGKGKLVDL ++   VVCRCQGGNNAGHTV+A   +Y FHLLPSGI+   + A+IGNGVV+NL+ L  EIN  + KGL D+  RL ISDR H+VF LHQ ID ++EE RG +++GTTKKGIGP YSSK TRNGLR+CDLIGDW  F  KYK+LV+Y+  RY  ++I+V++ LE+L  YR+ LS MV +++L +N+  +S ++KILVEGAQSCMLDIDFG+YP+VTSSNC +GGVCTGLGL P  + SV+GV+KAYTTRVG G FPTEL D IGE+ Q  G+E GVTT+R RR GWLDTV++RYAH+IN F A+ LTK+DVLD L EVK+ + YVD ++G  + +FPA+  IL  + V YE LPGWK ST+NCR + +LP  A+ F+E VEKL+ IPIRWIG GA R  II RSV
Sbjct:    9 VSVVLGAQWGDEGKGKLVDLLSESSTVVCRCQGGNNAGHTVVAGGKEYFFHLLPSGIINPNVLAIIGNGVVVNLEALFQEINEAVNKGLLDVASRLRISDRCHLVFPLHQEIDRMEEELRGLNLLGTTKKGIGPAYSSKVTRNGLRVCDLIGDWDQFTAKYKELVNYVKRRYPALEINVEESLEQLKTYREMLSGMVCDSVLLINKLTESKQTKILVEGAQSCMLDIDFGTYPHVTSSNCSIGGVCTGLGLSPSRVGSVYGVIKAYTTRVGSGPFPTELLDGIGEYIQKKGNEWGVTTKRMRRIGWLDTVVIRYAHIINDFNALALTKIDVLDGLKEVKIARAYVDPETGNELSSFPADPFILSRVVVIYETLPGWKASTQNCRVYDELPPAAKTFIETVEKLLNIPIRWIGTGASRDSIIIRSV 433
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BLAST of Adenylosuccinate synthetase vs. UniProt/SwissProt
Match: sp|C4QCD2|PURA_SCHMA (Adenylosuccinate synthetase OS=Schistosoma mansoni OX=6183 GN=Smp_055990 PE=3 SV=2)

HSP 1 Score: 508.834 bits (1309), Expect = 2.129e-177
Identity = 260/425 (61.18%), Postives = 325/425 (76.47%), Query Frame = 1 
Query:  136 VIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDIIYRSV 1410
            V V +GAQWGDEGKGKLVDL ++ C VVCRCQGGNNAGHTV+A   +Y FHLLPSGI+   + AVIGNGVV+NL+ L  EI+  + KGL D+  RL ISDR H+VFD+HQ ID ++EE RG + +GTTKKGIGPTYSSK TRNGLR+CDL+GDW  F  KYK+LV Y+  RY  + I+V++ LE+L       S MV ++++ +N+ +KS ++ ILVEGAQSCMLDIDFG+YP+VTSSNC VGGVCTGLGL P  +  V+GV+KAYTTRVG G FP+EL D IGE  Q  G E GVTT+RKRR GWLDTV++RYAH+IN F A+ LTK+DVLD+L+EVK+ K Y+D ++G  + +FP++  +L ++ V YE LPGWK ST  CR + +LP  A+VFVE VEKL+ IPIRWIG GA R  II RSV
Sbjct:    9 VSVVLGAQWGDEGKGKLVDLLSESCSVVCRCQGGNNAGHTVVAGGQEYFFHLLPSGIVNPNVLAVIGNGVVVNLQALFQEIDEAVCKGLLDVSSRLRISDRCHLVFDIHQEIDRMEEELRGENSLGTTKKGIGPTYSSKVTRNGLRVCDLMGDWVQFTAKYKELVKYVKRRYPKLGINVEESLEKL-------SGMVCDSVILINKLVKSKQANILVEGAQSCMLDIDFGTYPHVTSSNCSVGGVCTGLGLSPSRVGRVYGVIKAYTTRVGSGPFPSELLDGIGEFIQKKGCEWGVTTKRKRRIGWLDTVVIRYAHIINDFNALALTKIDVLDDLEEVKIAKAYIDPETGRELDSFPSDSSVLNHVVVVYETLPGWKTSTHGCRVYEELPTAAKVFVETVEKLLNIPIRWIGTGASRDSIIIRSV 426
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BLAST of Adenylosuccinate synthetase vs. UniProt/SwissProt
Match: sp|B5X2Z0|PUA1A_SALSA (Adenylosuccinate synthetase isozyme 1 A OS=Salmo salar OX=8030 GN=adss1a PE=2 SV=1)

HSP 1 Score: 489.96 bits (1260), Expect = 1.086e-169
Identity = 250/428 (58.41%), Postives = 319/428 (74.53%), Query Frame = 1 
Query:  124 KMSEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKR---GGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            K ++V V +GAQWGDEGKGK+VDL A E D++CRCQGGNNAGHTV+ + ++YDFHLLPSGI+     +VIGNGVVI+L  L+ E   N KKGL D ++RLIISDRAHIVFD HQ +DGLQE +R    G  IGTTKKGIGPTYSSKA+R GLRICDL+ D+  F  ++K L     A +  + +DV+  L++L  Y + + PMV++ + ++ + +     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP +I  V+GV+KAYTTRVG+G FPTE  +E+GE  Q  GHE+GVTT RKRR GWLD V+LRYA+MINGF A  LTKLD+LD +DE+KVG  Y  K  G+ I  FPANMD+L+ ++VEYE LPGWK  T  CR++ DLP +AQ +V  VE  +G+PI+W+GVG  R  +I
Sbjct:   21 KGNKVTVVLGAQWGDEGKGKVVDLLATESDIICRCQGGNNAGHTVVVDGMEYDFHLLPSGIINSKAVSVIGNGVVIHLPGLLEEAEKNEKKGLKDWEKRLIISDRAHIVFDFHQAVDGLQEVQRQAQDGKNIGTTKKGIGPTYSSKASRTGLRICDLLDDFKEFSTRFKNLAQQYQAMFPTLVVDVEGQLKKLKEYAERIRPMVRDGVYFMYDAINGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPLNIGDVYGVVKAYTTRVGIGAFPTEQLNEVGELLQTRGHEVGVTTGRKRRCGWLDLVILRYANMINGFTAFALTKLDILDVMDEIKVGVSY--KLKGKKIPYFPANMDVLQKVEVEYEKLPGWKSDTSACRKWEDLPVKAQNYVRFVENHVGVPIKWVGVGKARESMI 446
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BLAST of Adenylosuccinate synthetase vs. UniProt/SwissProt
Match: sp|Q561L1|PUA1A_XENLA (Adenylosuccinate synthetase isozyme 1 A OS=Xenopus laevis OX=8355 GN=adss1-a PE=2 SV=1)

HSP 1 Score: 484.567 bits (1246), Expect = 1.701e-167
Identity = 243/426 (57.04%), Postives = 317/426 (74.41%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRG---GSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            ++V V +GAQWGDEGKGK+VDL A + D++CRCQGGNNAGHTV+    +YDFHL PSGI+     + IGNGVVI+L  L  E + N KKGL D ++RLIISDRAHIVFD HQ +DGLQE +R    G  IGTTKKGIGPTYSSKA+R GLRICDL+ D+  F  ++K L     + + ++++DV+  L++L +Y +++ PMV++ + ++ E L     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP+++  V+GV+KAYTTRVG+G FPTE  +EIG   Q  GHE GVTT RKRR GWLD V+LRYAHMINGF A+ LTKLD+LD LDE+K+G  Y  + +G+ I  FPAN +IL+ ++VEYEV+PGWK  T   R++ DLP  AQ ++  VE  IG+P++W+GVG  R  +I
Sbjct:   28 NKVTVILGAQWGDEGKGKVVDLLATDSDIICRCQGGNNAGHTVVVEGKEYDFHLFPSGIINPKAISFIGNGVVIHLPGLFEEADKNEKKGLKDWEKRLIISDRAHIVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKASRTGLRICDLLSDFDEFSARFKNLAHQHQSMFSNLEVDVEGQLKKLKMYAEKIRPMVRDGVYFMYEALHGSPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNVGDVYGVVKAYTTRVGIGAFPTEQINEIGNILQTRGHEWGVTTGRKRRCGWLDLVILRYAHMINGFTALALTKLDILDVLDEMKIGVAY--RLNGKRIPYFPANQEILQKVEVEYEVMPGWKSDTTGARKWEDLPTRAQNYIRFVENHIGVPVKWVGVGKSRESMI 451
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BLAST of Adenylosuccinate synthetase vs. UniProt/SwissProt
Match: sp|B5DGM3|PUA1B_SALSA (Adenylosuccinate synthetase isozyme 1 B OS=Salmo salar OX=8030 GN=adss1b PE=2 SV=1)

HSP 1 Score: 484.182 bits (1245), Expect = 2.143e-167
Identity = 246/426 (57.75%), Postives = 316/426 (74.18%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRG---GSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            +++ V +GAQWGDEGKGK+VDL A E D++CRCQGGNNAGHTV+ +  +YDFHLLPSGI+     +VIGNGVVI+L  L  E   N K GL D ++RLIISDRAHIVFD HQ +DGLQE +R    G  IGTTKKGIGPTYSSKA+R GLRICDL+ D+  F  ++K L     A +  +++DV   L++L  Y + + PMV++ + ++ + +     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP +I  V+GV+KAYTTRVG+G FPTE  +E+GE  Q  GHE+GVTT RKRR GWLD V+LRYA+MINGF A  LTKLD+LD +DE+KVG  Y  K +G+ I  FPANMD+L+ ++VEYE LPGWK  T  CR++ DLP +AQ ++  VE  +G+PI+W+GVG  R  +I
Sbjct:   23 NKLTVVLGAQWGDEGKGKVVDLLATESDIICRCQGGNNAGHTVVVDGKEYDFHLLPSGIINSKALSVIGNGVVIHLPGLFEEAEKNEKNGLKDWEKRLIISDRAHIVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKASRTGLRICDLLADFKDFSMRFKNLAQQYQAMFPTLEVDVDGQLKKLKEYAERIRPMVRDGVYFMYDAINGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPLNIGDVYGVVKAYTTRVGIGAFPTEQLNEVGELLQTRGHEVGVTTGRKRRCGWLDLVILRYANMINGFTAFALTKLDILDVMDEIKVGVSY--KLNGKKIPYFPANMDVLQKVEVEYEKLPGWKSDTSACRKWEDLPVKAQNYIRFVEIHVGVPIKWVGVGKARESMI 446
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BLAST of Adenylosuccinate synthetase vs. TrEMBL
Match: A0A4E0RXK5 (Adenylosuccinate synthetase OS=Fasciola hepatica OX=6192 GN=D915_008689 PE=3 SV=1)

HSP 1 Score: 528.48 bits (1360), Expect = 0.000e+0
Identity = 261/431 (60.56%), Postives = 328/431 (76.10%), Query Frame = 1 
Query:  112 NSSYKMSEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDIIYR 1404
            N S + ++V V IGAQWGDEGKGKLVDL + + DV+CRCQGGNNAGHTV+ N  KY FH+LPSGI+     AVIGNG V+NL  L  EI+    KGL ++ +RL ISDR H+VFD HQ++DGL+EE RG  +IGTTKKGIGP YSSK TRNGLR+CDLIGDW  F  KY +LV Y+  RY +++I+ ++ LE LY YR+ LS MV +T+  +N+ L +   +ILVEGAQSCMLD+DFG+YP+VTSSNC VGGVCTGLGLPP  I  ++GV+KAYTTRVG G FPTEL D IGE  Q +G E GVTT+R+RR GWLDT+++RYAHMIN F A+ LTKLDVLD L EV++G  YV+ K+G  I+ FPA++ +L+N+ V Y  +PGW +ST+ C +F+DLP EAQ +V+ VE+  G+PIRWIG GA R  II R
Sbjct:    7 NGSTENTKVTVVIGAQWGDEGKGKLVDLLSSDSDVICRCQGGNNAGHTVMTNGQKYFFHMLPSGIINPHALAVIGNGTVVNLPALFEEIDEACNKGLEEVGKRLKISDRCHLVFDFHQLMDGLEEEIRGTGLIGTTKKGIGPAYSSKVTRNGLRMCDLIGDWDAFSIKYAELVDYVKRRYPNLEINTEESLERLYSYRKRLSGMVCDTVSLMNKLLNTPGCEILVEGAQSCMLDVDFGTYPFVTSSNCTVGGVCTGLGLPPSRIDVIYGVIKAYTTRVGSGVFPTELHDGIGERLQEIGQEFGVTTKRRRRVGWLDTMIVRYAHMINHFTALALTKLDVLDGLKEVRIGYSYVNTKTGNEIEDFPADLSVLENVTVLYHTMPGWSQSTRECCKFADLPPEAQAYVKAVERFCGVPIRWIGTGASRDAIIVR 437
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BLAST of Adenylosuccinate synthetase vs. TrEMBL
Match: A0A504YHK9 (Adenylosuccinate synthetase OS=Fasciola gigantica OX=46835 GN=FGIG_06025 PE=3 SV=1)

HSP 1 Score: 526.939 bits (1356), Expect = 0.000e+0
Identity = 260/431 (60.32%), Postives = 328/431 (76.10%), Query Frame = 1 
Query:  112 NSSYKMSEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDIIYR 1404
            N S K ++V V IGAQWGDEGKGKLVDL + + +V+CRCQGGNNAGHTV+ N  KY FH+LPSGI+     AVIGNG V+NL  L  EI+    KGL ++ +RL ISDR H+VFD HQ++D L+EE RG  +IGTTKKGIGP YSSK TRNGLR+CDLIGDWG F  KY +LV+Y+  RY  ++I+ ++ LE LY YR+ LS MV +T+  +N+ L +   +ILVEGAQSCMLD+DFG+YP+VTSSNC VGGVCTGLGLPP  I  ++GV+KAYTTRVG G FPTEL D IGE  Q +G E GVTT+R+RR GWLDT+++RYAH+IN F A+ LTKLDVLD L EV++G  YV+ K+G  I+ FPA++ +L+N+ V Y  +PGW +ST+ C +F+DLP EAQ +V+ VE+  G+PIRWIG GA R  II R
Sbjct:    7 NGSTKNTKVTVVIGAQWGDEGKGKLVDLLSSDSNVICRCQGGNNAGHTVMTNGQKYFFHMLPSGIINPHALAVIGNGTVVNLPALFEEIDEACNKGLEEVGKRLKISDRCHLVFDFHQLMDSLEEEIRGTGLIGTTKKGIGPAYSSKVTRNGLRMCDLIGDWGAFSIKYAELVNYVKRRYPKLEINTEESLERLYSYRKRLSGMVCDTVSLMNKLLNTPGCEILVEGAQSCMLDVDFGTYPFVTSSNCTVGGVCTGLGLPPSRIDVIYGVIKAYTTRVGSGVFPTELHDGIGERLQEIGQEFGVTTKRRRRVGWLDTMIVRYAHIINHFTALALTKLDVLDGLKEVRIGYSYVNTKTGNKIEDFPADLSVLENVTVLYHTMPGWSQSTRECCKFADLPPEAQAYVKAVERFCGVPIRWIGTGASRDAIIVR 437
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BLAST of Adenylosuccinate synthetase vs. TrEMBL
Match: A0A3Q0KG87 (Adenylosuccinate synthetase OS=Schistosoma mansoni OX=6183 PE=3 SV=1)

HSP 1 Score: 524.628 bits (1350), Expect = 0.000e+0
Identity = 264/425 (62.12%), Postives = 330/425 (77.65%), Query Frame = 1 
Query:  136 VIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDIIYRSV 1410
            V V +GAQWGDEGKGKLVDL ++ C VVCRCQGGNNAGHTV+A   +Y FHLLPSGI+   + AVIGNGVV+NL+ L  EI+  + KGL D+  RL ISDR H+VFD+HQ ID ++EE RG + +GTTKKGIGPTYSSK TRNGLR+CDL+GDW  F  KYK+LV Y+  RY  + I+V++ LE+L  YRQ+LS MV ++++ +N+ +KS ++ ILVEGAQSCMLDIDFG+YP+VTSSNC VGGVCTGLGL P  +  V+GV+KAYTTRVG G FP+EL D IGE  Q  G E GVTT+RKRR GWLDTV++RYAH+IN F A+ LTK+DVLD+L+EVK+ K Y+D ++G  + +FP++  +L ++ V YE LPGWK ST  CR + +LP  A+VFVE VEKL+ IPIRWIG GA R  II RSV
Sbjct:    9 VSVVLGAQWGDEGKGKLVDLLSESCSVVCRCQGGNNAGHTVVAGGQEYFFHLLPSGIVNPNVLAVIGNGVVVNLQALFQEIDEAVCKGLLDVSSRLRISDRCHLVFDIHQEIDRMEEELRGENSLGTTKKGIGPTYSSKVTRNGLRVCDLMGDWVQFTAKYKELVKYVKRRYPKLGINVEESLEQLRTYRQKLSGMVCDSVILINKLVKSKQANILVEGAQSCMLDIDFGTYPHVTSSNCSVGGVCTGLGLSPSRVGRVYGVIKAYTTRVGSGPFPSELLDGIGEFIQKKGCEWGVTTKRKRRIGWLDTVVIRYAHIINDFNALALTKIDVLDDLEEVKIAKAYIDPETGRELDSFPSDSSVLNHVVVVYETLPGWKTSTHGCRVYEELPTAAKVFVETVEKLLNIPIRWIGTGASRDSIIIRSV 433
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BLAST of Adenylosuccinate synthetase vs. TrEMBL
Match: A0A4Z2CYK6 (Adenylosuccinate synthetase OS=Schistosoma japonicum OX=6182 GN=EWB00_006388 PE=3 SV=1)

HSP 1 Score: 522.702 bits (1345), Expect = 2.691e-180
Identity = 264/425 (62.12%), Postives = 329/425 (77.41%), Query Frame = 1 
Query:  136 VIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDIIYRSV 1410
            V V +GAQWGDEGKGKLVDL ++   VVCRCQGGNNAGHTV+A   +Y FHLLPSGI+   + A+IGNGVV+NL+ L  EIN  + KGL D+  RL ISDR H+VF LHQ ID ++EE RG +++GTTKKGIGP YSSK TRNGLR+CDLIGDW  F  KYK+LV+Y+  RY  ++I+V++ LE+L  YR+ LS MV +++L +N+  +S ++KILVEGAQSCMLDIDFG+YP+VTSSNC +GGVCTGLGL P  + SV+GV+KAYTTRVG G FPTEL D IGE+ Q  G+E GVTT+R RR GWLDTV++RYAH+IN F A+ LTK+DVLD L EVK+ + YVD ++G  + +FPA+  IL  + V YE LPGWK ST+NCR + +LP  A+ F+E VEKL+ IPIRWIG GA R  II RSV
Sbjct:    9 VSVVLGAQWGDEGKGKLVDLLSESSTVVCRCQGGNNAGHTVVAGGKEYFFHLLPSGIINPNVLAIIGNGVVVNLEALFQEINEAVNKGLLDVASRLRISDRCHLVFPLHQEIDRMEEELRGLNLLGTTKKGIGPAYSSKVTRNGLRVCDLIGDWDQFTAKYKELVNYVKRRYPALEINVEESLEQLKTYREMLSGMVCDSVLLINKLTESKQTKILVEGAQSCMLDIDFGTYPHVTSSNCSIGGVCTGLGLSPSRVGSVYGVIKAYTTRVGSGPFPTELLDGIGEYIQKKGNEWGVTTKRMRRIGWLDTVVIRYAHIINDFNALALTKIDVLDGLKEVKIARAYVDPETGNELSSFPADPFILSRVVVIYETLPGWKASTQNCRVYDELPPAAKTFIETVEKLLNIPIRWIGTGASRDSIIIRSV 433
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BLAST of Adenylosuccinate synthetase vs. TrEMBL
Match: A0A430QK45 (Adenylosuccinate synthetase OS=Schistosoma bovis OX=6184 GN=DC041_0008621 PE=3 SV=1)

HSP 1 Score: 516.924 bits (1330), Expect = 5.288e-178
Identity = 262/425 (61.65%), Postives = 326/425 (76.71%), Query Frame = 1 
Query:  136 VIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDIIYRSV 1410
            V V +GAQWGDEGKGKLVDL ++   VVCRCQGGNNAGHTV+A   +Y FHLLPSGI+   + AVIGNGVV+NL+ L  EI+  + KGL D+  RL ISDR H+VFD+HQ ID ++EE RG + +GTTKKGIGPTYSSK TRNGLR+CDL+GDW  F  KY++LV+Y+  RY  ++  V++ LE+L  YRQ+LS MV +++  +N+ ++S ++ ILVEGAQSCMLDIDFG+YP+VTSSNC VGGVCTGLGL P  +  V+GV+KAYTTRVG G FPTEL D IGE  Q  G E GVTT+RKRR GWLDTV++RYAH+IN F A+ LTK+DVLD+L+EVK+ K YVD ++G  + +FP++  +L  + V YE LPGWK ST  CR +  LP  A+VFVE VEKL+ IPIRWIG GA R  II RSV
Sbjct:    9 VSVVLGAQWGDEGKGKLVDLLSESSGVVCRCQGGNNAGHTVVAGGQEYFFHLLPSGIVNPNVLAVIGNGVVVNLQALFQEIDEAVSKGLLDVASRLRISDRCHLVFDIHQEIDRMEEELRGVNSLGTTKKGIGPTYSSKVTRNGLRVCDLMGDWVQFTAKYRELVNYVKRRYPKLETSVEQSLEQLKTYRQKLSGMVCDSVTLINKLVESKQANILVEGAQSCMLDIDFGTYPHVTSSNCSVGGVCTGLGLSPSRVGPVYGVIKAYTTRVGSGTFPTELLDGIGEFIQKKGCEWGVTTKRKRRIGWLDTVVIRYAHIINDFNALALTKIDVLDDLEEVKIAKAYVDPETGCELDSFPSDSSVLNRVVVVYETLPGWKTSTHGCRVYEKLPTAAKVFVETVEKLLNIPIRWIGTGASRDSIIIRSV 433
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BLAST of Adenylosuccinate synthetase vs. Ensembl Cavefish
Match: adss1 (adenylosuccinate synthase 1 [Source:NCBI gene;Acc:107197724])

HSP 1 Score: 481.871 bits (1239), Expect = 2.619e-167
Identity = 244/426 (57.28%), Postives = 313/426 (73.47%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRG---GSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            + V V +GAQWGDEGKGK+VDL A E D+VCRCQGGNNAGHTV+    +YDFHLLPSGI+     ++IGNGVVI+L  L  EI+ N KKGL    +RL+ISDRAHIVFD HQ +DG+QE +R    G  IGTTKKGIGPTYS KA+R GLR+CDL+ D+  F  ++K L     + Y  +K+DV+ +L++L  Y + + PMV++ + ++ + +     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP +I  V+GV KAYTTRVG+G FPTE  + +GE  Q  GHE+GVTT RKRR GWLD V+LRYAHMINGF A+ LTKLD+LD LDE+KVG  Y  K  G+ I  FPANM++L+ ++VEYE  PGWK  T   R+++DLP +AQ ++  VE  IG+PI+W+GVG  R  +I
Sbjct:   30 NRVTVVLGAQWGDEGKGKVVDLLATESDIVCRCQGGNNAGHTVVVEGTEYDFHLLPSGIINTKCISLIGNGVVIHLPGLFEEIDKNEKKGLKGWDKRLVISDRAHIVFDFHQAVDGVQEVQRQAQEGKNIGTTKKGIGPTYSCKASRTGLRVCDLLADFKEFSLRFKNLAQQYQSMYPALKVDVEGELKKLKDYAERIRPMVRDGVYFMYDAIHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPANIGDVYGVSKAYTTRVGIGAFPTEQLNAVGELLQTRGHEVGVTTGRKRRCGWLDLVILRYAHMINGFTAIALTKLDILDVLDEIKVGVAY--KLGGKRIPHFPANMEVLQKVEVEYETFPGWKADTSAARKWNDLPPKAQNYIRFVENNIGVPIKWVGVGKSRECMI 453
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BLAST of Adenylosuccinate synthetase vs. Ensembl Cavefish
Match: adss2 (adenylosuccinate synthase 2 [Source:NCBI gene;Acc:103022801])

HSP 1 Score: 473.011 bits (1216), Expect = 5.103e-164
Identity = 238/428 (55.61%), Postives = 310/428 (72.43%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEI--NVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKR---GGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            + V V +GAQWGDEGKGK+VDL AQ+ D+VCRCQGGNNAGHTV+ ++V+YDFHLLPSGI+   +TA IGNGVVI+L  L  E   NV   KGL   ++RL+ISDRAHIVFD HQ +DG+QE++R    G  +GTTKKGIGP YS+KA R+GLRICDL+ D+  F E+YK L     + Y  ++ID+  +L +L  Y   + PMV++ + ++ E L      ILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP+++  V+GV+KAYTTRVG+G FP+E  +E GE  Q  G E+GVTT RKRR GWLD V+++YAHMINGF A+ LTKLD+LD   E+KVG  Y  K   E I  FPAN ++L+ ++V+YE LPGW   T   R F +LP  AQ +V  +E+ +G+P++WIGVG  R  +I
Sbjct:   12 NRVTVVLGAQWGDEGKGKVVDLLAQDADMVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPKVTAFIGNGVVIHLPGLFEEAEKNVRKGKGLEGWEKRLVISDRAHIVFDFHQAVDGVQEQERQQQAGKNLGTTKKGIGPVYSAKAARSGLRICDLLSDFQEFSERYKNLALQYKSMYPSLEIDIDGELGKLEAYVDRIKPMVRDGVFFMYEALHGPPKTILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPSEQSNETGELLQTRGKEVGVTTGRKRRCGWLDLVLVKYAHMINGFTALALTKLDILDVFPEIKVGVAY--KVDNECIPHFPANQEVLQRVEVQYETLPGWNSDTSAARTFEELPDNAQKYVRFIEEQLGVPVKWIGVGKSRESMI 437
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BLAST of Adenylosuccinate synthetase vs. Ensembl Cavefish
Match: adssl (adenylosuccinate synthetase isozyme 2-like [Source:NCBI gene;Acc:103028434])

HSP 1 Score: 471.085 bits (1211), Expect = 7.627e-163
Identity = 237/428 (55.37%), Postives = 314/428 (73.36%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKG--LSDIKQRLIISDRAHIVFDLHQMIDGLQEEKR---GGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            ++V V +GAQWGDEGKGK+VDL A + D+VCRCQGGNNAGHTV+ ++V+YDFHLLPSG+L K   + IGNGVVI+L  L  E   NM+KG  L   ++RL ISDRAHIVF+ HQ +DG+QE++R    G  +GTTKKGIGP YSSKA RNGLR+CDL+ D+ +FEEK++ L S+    Y ++ IDV  +LE+L  Y + L P+V + + ++++ L     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP  +  V+GV+KAYTTRVGVG FPTE  +++G+  Q  G E GVTT R+RR GWLD V++RYAHM+NGF A+ LTKLD+LD L E+KVG  Y     G+ + +FPANMD+L  + V YE LPGW  ST+  R F +LP +AQ ++  +E  + +P++W+GVG  R  +I
Sbjct:   42 NKVTVVLGAQWGDEGKGKVVDLLAMDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGVLNKKALSFIGNGVVIHLPGLFEEAEKNMQKGNGLQGWEERLKISDRAHIVFNFHQAVDGIQEQQRQQQAGKNLGTTKKGIGPAYSSKAARNGLRVCDLVSDFSVFEEKFRVLASHFQTMYPNLNIDVDAELEQLMGYAERLRPLVTDGVYFMHKALTGPSKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGVPPSHVGRVYGVVKAYTTRVGVGAFPTEQNNDVGDLLQSKGREFGVTTGRRRRCGWLDLVLVRYAHMVNGFTAIALTKLDILDTLPEIKVGVAYT--VDGKPLPSFPANMDVLTKVSVTYETLPGWCCSTEGARNFDELPAQAQAYICFIEDFLQVPVKWVGVGKSRESMI 467
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BLAST of Adenylosuccinate synthetase vs. Ensembl Cavefish
Match: adss1 (adenylosuccinate synthase 1 [Source:NCBI gene;Acc:107197724])

HSP 1 Score: 457.988 bits (1177), Expect = 6.655e-158
Identity = 241/428 (56.31%), Postives = 307/428 (71.73%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRG---GSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEK--YKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            + V V +GAQWGDEGKGK+VDL A E D+VCRCQGGNNAGHTV+    +YDFHLLPSGI+     ++IGNGVVI+L  L  EI+ N KKGL    +RL+ISDRAHIVFD HQ +DG+QE +R    G  IGTTKKGIGPTYS KA+R GLR+CDL+ D+  F  +  +  ++ YI      V ++    L  L  Y + + PMV++ + ++ + +     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP +I  V+GV KAYTTRVG+G FPTE  + +GE  Q  GHE+GVTT RKRR GWLD V+LRYAHMINGF A+ LTKLD+LD LDE+KVG  Y  K  G+ I  FPANM++L+ ++VEYE  PGWK  T   R+++DLP +AQ ++  VE  IG+PI+W+GVG  R  +I
Sbjct:   30 NRVTVVLGAQWGDEGKGKVVDLLATESDIVCRCQGGNNAGHTVVVEGTEYDFHLLPSGIINTKCISLIGNGVVIHLPGLFEEIDKNEKKGLKGWDKRLVISDRAHIVFDFHQAVDGVQEVQRQAQEGKNIGTTKKGIGPTYSCKASRTGLRVCDLLADFKEFSLRAVHTFMLMYINLFVVFVFLNFLSCL--LQDYAERIRPMVRDGVYFMYDAIHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPANIGDVYGVSKAYTTRVGIGAFPTEQLNAVGELLQTRGHEVGVTTGRKRRCGWLDLVILRYAHMINGFTAIALTKLDILDVLDEIKVGVAY--KLGGKRIPHFPANMEVLQKVEVEYETFPGWKADTSAARKWNDLPPKAQNYIRFVENNIGVPIKWVGVGKSRECMI 453
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BLAST of Adenylosuccinate synthetase vs. Ensembl Cavefish
Match: adss2 (adenylosuccinate synthase 2 [Source:NCBI gene;Acc:103022801])

HSP 1 Score: 447.588 bits (1150), Expect = 2.151e-154
Identity = 227/426 (53.29%), Postives = 298/426 (69.95%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKR---GGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            + V V +GAQWGDEGKGK+VDL AQ+ D+VCRCQGGNNAGHTV+ ++V+YDFHLLPSGI+   +TA IGNGVVI+L  L  E   N++KG                VFD HQ +DG+QE++R    G  +GTTKKGIGP YS+KA R+GLRICDL+ D+  F E+YK L     + Y  ++ID+  +L +L  Y   + PMV++ + ++ E L      ILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP+++  V+GV+KAYTTRVG+G FP+E  +E GE  Q  G E+GVTT RKRR GWLD V+++YAHMINGF A+ LTKLD+LD   E+KVG  Y  K   E I  FPAN ++L+ ++V+YE LPGW   T   R F +LP  AQ +V  +E+ +G+P++WIGVG  R  +I
Sbjct:   12 NRVTVVLGAQWGDEGKGKVVDLLAQDADMVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPKVTAFIGNGVVIHLPGLFEEAEKNVRKGK---------------VFDFHQAVDGVQEQERQQQAGKNLGTTKKGIGPVYSAKAARSGLRICDLLSDFQEFSERYKNLALQYKSMYPSLEIDIDGELGKLEAYVDRIKPMVRDGVFFMYEALHGPPKTILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPSEQSNETGELLQTRGKEVGVTTGRKRRCGWLDLVLVKYAHMINGFTALALTKLDILDVFPEIKVGVAY--KVDNECIPHFPANQEVLQRVEVQYETLPGWNSDTSAARTFEELPDNAQKYVRFIEEQLGVPVKWIGVGKSRESMI 420
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BLAST of Adenylosuccinate synthetase vs. Ensembl Sea Lamprey
Match: adss2 (adenylosuccinate synthase 2 [Source:NCBI gene;Acc:550502])

HSP 1 Score: 429.483 bits (1103), Expect = 2.004e-147
Identity = 228/434 (52.53%), Postives = 300/434 (69.12%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKG----LSDIKQRLIISDRAHIVFDLHQMIDGLQEEKR---GGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRR---TGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWY-VDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            +++ V +GAQWGDEGKGK+VD+ A   D+VCRCQGGNNAGHTV+ ++V+YDFHLLPSGI+ K  T+ IGNGVVI+L  L  E   N KKG    L D  +RL+ISDRAHIVFD HQ +DGLQE +R    G  +GTTKKGIGP YS+KA+R+GLRICDL+ D+  F E++K L  +    Y  ++ID +  L++L +Y   + PMVK+ + ++ E L     KILVEGA + +LDIDFG+YP+VTSSNC VGGV TGLG+PP+++  V+GV+KAYTTRVGVG FPTE  +++GE  Q  G E+GVTT RKR     G    V L +  ++     + LTKLD+LD   E+KVG  Y +D K    I  FPAN ++L  ++VEY+ LPGW  ST + R F +LP  AQ +V  +E  +G+PI+WIGVG  R  +I
Sbjct:   29 NKITVVLGAQWGDEGKGKVVDMLATTADLVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINKNATSYIGNGVVIHLPGLFEEAEKNEKKGKVSGLKDWDKRLVISDRAHIVFDFHQDVDGLQEVQRQSEAGKNLGTTKKGIGPVYSAKASRSGLRICDLLADFTYFSERFKGLARHYQTMYPSLQIDTEDQLKKLKVYADRIRPMVKDGVYFMYEALHGEPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVLTGLGVPPQNVGEVYGVVKAYTTRVGVGAFPTEQTNDVGELLQTRGREVGVTTGRKRTLRLIGLRWCVTLAWPTLLFPTR-LALTKLDILDVFSEIKVGISYKIDDKP---IPYFPANQEVLNKVEVEYKTLPGWNTSTADARTFEELPAAAQSYVRFIENQLGVPIKWIGVGKARESMI 458
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BLAST of Adenylosuccinate synthetase vs. Ensembl Yeast
Match: ADE12 (Adenylosuccinate synthase; catalyzes the first step in synthesis of adenosine monophosphate from inosine 5'monophosphate during purine nucleotide biosynthesis; exhibits binding to single-stranded autonomously replicating (ARS) core sequence [Source:SGD;Acc:S000005164])

HSP 1 Score: 414.846 bits (1065), Expect = 3.491e-142
Identity = 207/434 (47.70%), Postives = 296/434 (68.20%), Query Frame = 1 
Query:  136 VIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQE-----EKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGD----WGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDIIYRSV 1410
            V V +G+QWGDEGKGKLVDL   + D+V RC GGNNAGHT++ + VKYDFH+LPSG++      ++GNGVVI++     E+     KGL + + RL +S RAH+VFD HQ+ D L+E       + G  IGTT KGIGPTYS+KA+R+GLR+  L+ D    W  F  +YK+L+     RYGD + D +  L E    R++L P V +++++++  +++ K KILVEGA + MLDIDFG+YPYVTSSN  +GGV TGLG+PPR+I  ++GV+KAYTTRVG G FPTE  +E GE  Q +G E GVTT RKRR GWLD V+L+Y+ +ING+ ++ +TKLDVLD   E+ VG  Y     G+ +  FP +++IL  ++VEY+VLPGW +      ++ DLP+ A+ +++ +E  +G+P+ W+G G  R  ++++ +
Sbjct:    2 VNVVLGSQWGDEGKGKLVDLLVGKYDIVARCAGGNNAGHTIVVDGVKYDFHMLPSGLVNPNCQNLLGNGVVIHVPSFFKELETLEAKGLKNARSRLFVSSRAHLVFDFHQVTDKLRELELSGRSKDGKNIGTTGKGIGPTYSTKASRSGLRVHHLVNDQPGAWEEFVARYKRLLETRRQRYGDFEYDFEAKLAEYKKLREQLKPFVVDSVVFMHNAIEA-KKKILVEGANALMLDIDFGTYPYVTSSNTGIGGVLTGLGIPPRTIDEIYGVVKAYTTRVGEGPFPTEQLNENGEKLQTIGAEFGVTTGRKRRCGWLDLVVLKYSTLINGYTSLNITKLDVLDTFKEIPVGISY--SIQGKKLDLFPEDLNILGKVEVEYKVLPGWDQDITKITKYEDLPENAKKYLKYIEDFVGVPVEWVGTGPARESMLHKEI 432
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BLAST of Adenylosuccinate synthetase vs. Ensembl Nematostella
Match: EDO32382 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SV96])

HSP 1 Score: 466.077 bits (1198), Expect = 8.496e-162
Identity = 224/423 (52.96%), Postives = 313/423 (74.00%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            ++V V +GAQWGDEGKGKLVD+ A   DVVCRCQGGNNAGHTV+  +  Y  H+LPSG++      VIGNGVVI++     E+     KG+ + K RLIIS+RAH+VFDLHQ  D L+E   G + +GTTKKGIGP Y+SKA R  LR+CDL+GD+ +F EK+  L  +    Y D+ +D++ +L++  ++ +++ P+ ++T+ ++N+ L++  ++++VEGA + MLDIDFG+YP+VTSSNC VG VCTGLG+PP++I +V+GV KAYTTRVG+G FPTELFDE+G   Q +G E GVTT R+RR GWLD VM++Y+HMINGF A+ + KLDVLD  +EVK+G  Y  +  GE++ ++PA++++L  ++VEY  LPGWK S  NCR F DLP+ AQVFV+ VE+++ IP+ W+GVG  R  +I
Sbjct:   20 TKVTVVLGAQWGDEGKGKLVDILATNADVVCRCQGGNNAGHTVVVGDKHYALHMLPSGMINPHSMNVIGNGVVIHIPQFFEELEKLEAKGIPEWKDRLIISERAHLVFDLHQEADKLKES--GKTSLGTTKKGIGPAYASKAQRLNLRVCDLLGDFSVFAEKFTSLAHHFQRLYPDLVVDIEDELKKYKVFAEKVRPLARDTVSFMNKILQTPDNRVVVEGANALMLDIDFGTYPFVTSSNCSVGAVCTGLGIPPQAIGNVYGVTKAYTTRVGMGAFPTELFDELGNQMQEIGREFGVTTGRRRRCGWLDLVMIKYSHMINGFTALAIAKLDVLDTFEEVKLGVAY--RYKGELLSSYPASLEVLSKVEVEYLTLPGWKTSITNCRSFDDLPQNAQVFVKKVEEIVQIPVNWVGVGQARDQMI 438
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BLAST of Adenylosuccinate synthetase vs. Ensembl Nematostella
Match: EDO29959 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T255])

HSP 1 Score: 167.162 bits (422), Expect = 3.839e-47
Identity = 75/147 (51.02%), Postives = 105/147 (71.43%), Query Frame = 1 
Query:  958 FPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            FP +   E+G   Q +G E GVTT R+RR GWLD VM++Y+HMINGF A+ + KLDVLD  +EVK+G  Y  +  GE++ ++PA++++L  ++VEY  LPGWK S  NCR F DLP+ AQVFV+ VE+++ IP+ W+GVG  R  +I
Sbjct:  205 FPLQ---ELGNQMQEIGREFGVTTGRRRRCGWLDLVMIKYSHMINGFTALAIAKLDVLDTFEEVKLGVAY--RYKGELLSSYPASLEVLSKVEVEYLTLPGWKMSITNCRSFDDLPQNAQVFVKKVEEIVQIPVNWVGVGQARDQMI 346

HSP 2 Score: 158.303 bits (399), Expect = 5.763e-44
Identity = 91/200 (45.50%), Postives = 120/200 (60.00%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLP--SGILQKGITAVIG-NGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEK--YKKLVSYICARYGDVKIDVKKDLEELYLYRQEL 714
            ++V V +GAQWGDEGKGKLVD+ A   DVVCRCQGGNNAGHTV+  +  Y  H+LP  SG  ++      G NGVVI++     E+     KG+ + K RLIIS+RAH+VFDLHQ  D L+E   G + +GTTKKGIGP Y+SK  R    +   + +  L E    Y+ L +  C     V + +   L+EL    QE+
Sbjct:   20 TKVTVVLGAQWGDEGKGKLVDILATNADVVCRCQGGNNAGHTVVVGDKHYALHMLPSLSGRDKQPANFCPGRNGVVIHIPQFFEELEKLEAKGIPEWKDRLIISERAHLVFDLHQEADKLKES--GKTSLGTTKKGIGPAYASKVLRWLCLLYTAMSEASLMEHHFLYQNLFATPCPPILSVVLTIFFPLQELGNQMQEI 217
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BLAST of Adenylosuccinate synthetase vs. Ensembl Medaka
Match: adss1 (adenylosuccinate synthetase isozyme 1 C [Source:NCBI gene;Acc:101171790])

HSP 1 Score: 487.263 bits (1253), Expect = 2.160e-169
Identity = 245/426 (57.51%), Postives = 315/426 (73.94%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRG---GSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            ++V V +GAQWGDEGKGK+VDL A E D+VCRCQGGNNAGHTV+ +  +YDFHLLPSGI+     ++IGNGVVI+L  L  E + N KKGL   ++RLI+SDRAH+VFD HQ++DGLQE +R    G  IGTTKKGIGP YSSKA+R GLR+CDL+GD+  F  ++K LV    + Y  +  DV++ L++L  Y + L PMV++ + ++ E L     KILVEGA + +LDIDFG+YP+VTSSNC VGG CTGLG+PP +I  V+GV KAYTTRVG+G FPTE  + +GE  Q  GHE+GVTT RKRR GWLD V++RYAHMINGF A+ LTKLD+LD LDE+KVG  Y  K +G+ I  FPANMD+L  ++VEYE  PGWK  T   R+++DLP +AQ ++  +E  IG+PI+W+GVG  R  +I
Sbjct:   31 NKVTVVLGAQWGDEGKGKVVDLLATEADIVCRCQGGNNAGHTVVVDGKEYDFHLLPSGIINSKSVSLIGNGVVIHLPGLFEEGDKNEKKGLKGWEKRLIVSDRAHLVFDFHQVVDGLQETERQAQEGKNIGTTKKGIGPAYSSKASRTGLRVCDLLGDFKDFSTRFKNLVHQYQSMYPSLTADVEEQLKKLKEYAERLRPMVRDGVYYMYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGACTGLGIPPMNIGDVYGVSKAYTTRVGIGAFPTEQLNAVGELLQTRGHEVGVTTGRKRRCGWLDLVIVRYAHMINGFTAIALTKLDILDVLDEIKVGVAY--KLNGKRIPHFPANMDVLHKVEVEYETFPGWKTDTSAARKWNDLPAKAQNYIRFIENHIGVPIKWVGVGKSRECMI 454
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BLAST of Adenylosuccinate synthetase vs. Ensembl Medaka
Match: adss2 (adenylosuccinate synthetase isozyme 2 [Source:NCBI gene;Acc:101162945])

HSP 1 Score: 479.945 bits (1234), Expect = 1.284e-166
Identity = 239/428 (55.84%), Postives = 318/428 (74.30%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKG--LSDIKQRLIISDRAHIVFDLHQMIDGLQEEKR---GGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            ++V V +GAQWGDEGKGK+VDL AQ+ D+VCRCQGGNNAGHTV+ ++V+YDFHLLPSGI+   +TA IGNGVVI++  +  E   N +KG  L   ++RLIISDRAHIVFD HQ +DG+QE++R    G  +GTTKKGIGP YS+KA R+GLRICDL+ D+  F E+YK L     + Y  ++ID++ +LE L  Y + + PMV++ + ++ E L+    KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP ++  V+GV+KAYTTRVG+G FPTE  +++GE  Q  G E+GVTT RKRR GWLD V+++YA+MINGF A+ LTKLD+LD   E+KVG  Y  K + EII  FPAN ++L  ++V+YE LPGWK  T   R F +LP+ AQ +V  +E+ +G+P++WIGVG  R  +I
Sbjct:   25 NKVTVVLGAQWGDEGKGKVVDLLAQDADMVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPKVTAFIGNGVVIHIPGMFEEAEKNERKGKGLKGWEKRLIISDRAHIVFDFHQAVDGVQEQQREEQAGKNLGTTKKGIGPVYSAKAARSGLRICDLLADFTQFSERYKILAHQYKSMYPTLEIDIEGELERLKHYLERIRPMVRDGVYFMYEALRGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPHNVGEVYGVVKAYTTRVGIGAFPTEQSNDVGELLQTRGKEVGVTTGRKRRCGWLDLVLIKYANMINGFTAIALTKLDILDVFPEIKVGIAY--KVNDEIIPHFPANQEVLHRVEVQYETLPGWKSDTSAARSFEELPENAQKYVHFIEEHVGVPVKWIGVGKSRESMI 450
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BLAST of Adenylosuccinate synthetase vs. Ensembl Medaka
Match: adssl (adenylosuccinate synthetase isozyme 2 [Source:NCBI gene;Acc:101161325])

HSP 1 Score: 471.47 bits (1212), Expect = 5.797e-163
Identity = 238/428 (55.61%), Postives = 318/428 (74.30%), Query Frame = 1 
Query:  130 SEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKG--LSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRG---GSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDII 1398
            ++V V +GAQWGDEGKGK+VDL A + D+VCRCQGGNNAGHTV+ ++V+YDFHLLPSG+L K  T+ IGNGVVI+L  L  E   N++KG  L   ++RL IS+RAHIVF+ HQ +DG+QE++R    G  +GTTKKGIGP YSSKA RNGLR+CDL+ D+ +FE+KY+KL  +    Y  + I+++++LE+L  + + L P+V + + ++++ L     KILVEGA + +LDIDFG+YP+VTSSNC VGGVCTGLG+PP  +  V+GV+KAYTTRVGVG FPTE  ++IGE  Q  G E GVTT R+RR GWLD V++RYAHM+NGF A+ LTKLD+LD L E+KVG  Y  K  GE + +FPANMD+L  + V+YE LPGW  ST+  R F DLP +AQ ++  +E  + +P++W+GVG  R  +I
Sbjct:   45 NKVTVVLGAQWGDEGKGKVVDLLAMDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGVLNKKATSFIGNGVVIHLPGLFEEAEKNLQKGKGLQGWEERLKISERAHIVFNFHQAVDGIQEQQRQQQEGKNLGTTKKGIGPAYSSKAARNGLRVCDLVSDFSVFEDKYRKLAEHYKRMYPKLNINIEEELEQLKGFAERLRPLVTDGVYFMHKALTGPSKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGVPPSYVGRVYGVVKAYTTRVGVGAFPTEQDNDIGELLQSRGREFGVTTGRRRRCGWLDLVLVRYAHMVNGFSAIALTKLDILDTLPEIKVGVAY--KVDGEPLPSFPANMDVLTRVVVDYETLPGWCCSTETARSFEDLPPQAQNYIRFIEDFLQVPVKWVGVGKSRESMI 470
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BLAST of Adenylosuccinate synthetase vs. Planmine SMEST
Match: SMESG000078697.1 (SMESG000078697.1)

HSP 1 Score: 836.639 bits (2160), Expect = 0.000e+0
Identity = 425/428 (99.30%), Postives = 427/428 (99.77%), Query Frame = 1 
Query:  127 MSEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNXXXXXXXXXXXXPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFVEIVEKLIGIPIRWIGVGADRTDIIYRSV 1410
            MSEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNCCVGGVCTGLGLPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKK+TKNCREFS+LPKEAQVFVEIVEKLI IPIRWIGVGADRTDIIYRSV
Sbjct:    1 MSEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVKYDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLIISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRICDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMVKNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNCCVGGVCTGLGLPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVTTQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDKKSGEIIKTFPANMDILKNIDVEYEVLPGWKKTTKNCREFSNLPKEAQVFVEIVEKLIEIPIRWIGVGADRTDIIYRSV 428
The following BLAST results are available for this feature:
BLAST of Adenylosuccinate synthetase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ADSS22.027e-16456.78adenylosuccinate synthase 2 [Source:HGNC Symbol;Ac... [more]
ADSS11.989e-16256.34adenylosuccinate synthase 1 [Source:HGNC Symbol;Ac... [more]
ADSS18.115e-14355.47adenylosuccinate synthase 1 [Source:HGNC Symbol;Ac... [more]
ADSS14.205e-2160.27adenylosuccinate synthase 1 [Source:HGNC Symbol;Ac... [more]
ADSS15.819e-1443.33adenylosuccinate synthase 1 [Source:HGNC Symbol;Ac... [more]
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BLAST of Adenylosuccinate synthetase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
adss-16.344e-13548.13Adenylosuccinate synthetase [Source:UniProtKB/Swi... [more]
adss-17.859e-13548.13Adenylosuccinate synthetase [Source:UniProtKB/Swi... [more]
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BLAST of Adenylosuccinate synthetase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
AdSS7.253e-16455.56gene:FBgn0027493 transcript:FBtr0083991[more]
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BLAST of Adenylosuccinate synthetase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
adss23.672e-16757.01adenylosuccinate synthase 2 [Source:NCBI gene;Acc:... [more]
adss12.914e-16657.04adenylosuccinate synthase 1 [Source:NCBI gene;Acc:... [more]
adssl1.831e-16554.44adenylosuccinate synthase, like [Source:ZFIN;Acc:Z... [more]
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BLAST of Adenylosuccinate synthetase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
il17c9.533e-16557.24interleukin 17C [Source:Xenbase;Acc:XB-GENE-959427... [more]
ppp2r2d9.836e-16556.34protein phosphatase 2 regulatory subunit B, delta ... [more]
il17c2.435e-16457.24interleukin 17C [Source:Xenbase;Acc:XB-GENE-959427... [more]
ppp2r2d3.632e-16054.30protein phosphatase 2 regulatory subunit B, delta ... [more]
il17c3.482e-15755.16interleukin 17C [Source:Xenbase;Acc:XB-GENE-959427... [more]
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BLAST of Adenylosuccinate synthetase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Adss6.709e-16557.01adenylosuccinate synthetase, non muscle [Source:MG... [more]
Adssl11.285e-16356.81adenylosuccinate synthetase like 1 [Source:MGI Sym... [more]
Adssl15.765e-15853.90adenylosuccinate synthetase like 1 [Source:MGI Sym... [more]
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BLAST of Adenylosuccinate synthetase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5D8V5|PURA_SCHJA0.000e+062.12Adenylosuccinate synthetase OS=Schistosoma japonic... [more]
sp|C4QCD2|PURA_SCHMA2.129e-17761.18Adenylosuccinate synthetase OS=Schistosoma mansoni... [more]
sp|B5X2Z0|PUA1A_SALSA1.086e-16958.41Adenylosuccinate synthetase isozyme 1 A OS=Salmo s... [more]
sp|Q561L1|PUA1A_XENLA1.701e-16757.04Adenylosuccinate synthetase isozyme 1 A OS=Xenopus... [more]
sp|B5DGM3|PUA1B_SALSA2.143e-16757.75Adenylosuccinate synthetase isozyme 1 B OS=Salmo s... [more]
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BLAST of Adenylosuccinate synthetase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E0RXK50.000e+060.56Adenylosuccinate synthetase OS=Fasciola hepatica O... [more]
A0A504YHK90.000e+060.32Adenylosuccinate synthetase OS=Fasciola gigantica ... [more]
A0A3Q0KG870.000e+062.12Adenylosuccinate synthetase OS=Schistosoma mansoni... [more]
A0A4Z2CYK62.691e-18062.12Adenylosuccinate synthetase OS=Schistosoma japonic... [more]
A0A430QK455.288e-17861.65Adenylosuccinate synthetase OS=Schistosoma bovis O... [more]
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BLAST of Adenylosuccinate synthetase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
adss12.619e-16757.28adenylosuccinate synthase 1 [Source:NCBI gene;Acc:... [more]
adss25.103e-16455.61adenylosuccinate synthase 2 [Source:NCBI gene;Acc:... [more]
adssl7.627e-16355.37adenylosuccinate synthetase isozyme 2-like [Source... [more]
adss16.655e-15856.31adenylosuccinate synthase 1 [Source:NCBI gene;Acc:... [more]
adss22.151e-15453.29adenylosuccinate synthase 2 [Source:NCBI gene;Acc:... [more]
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BLAST of Adenylosuccinate synthetase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
adss22.004e-14752.53adenylosuccinate synthase 2 [Source:NCBI gene;Acc:... [more]
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BLAST of Adenylosuccinate synthetase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
ADE123.491e-14247.70Adenylosuccinate synthase; catalyzes the first ste... [more]
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BLAST of Adenylosuccinate synthetase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO323828.496e-16252.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO299593.839e-4751.02Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Adenylosuccinate synthetase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
adss12.160e-16957.51adenylosuccinate synthetase isozyme 1 C [Source:NC... [more]
adss21.284e-16655.84adenylosuccinate synthetase isozyme 2 [Source:NCBI... [more]
adssl5.797e-16355.61adenylosuccinate synthetase isozyme 2 [Source:NCBI... [more]
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BLAST of Adenylosuccinate synthetase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000078697.10.000e+099.30SMESG000078697.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003172 ID=SMED30003172|Name=Adenylosuccinate synthetase|organism=Schmidtea mediterranea sexual|type=transcript|length=1555bp
GTTTAATTTTCGCGTAATATGCATAGCAGTTTATATTTCATTATATAATA
TGATTTAATTTTGTAGAAATATTTACAAAAGTCATATTTAAAAAATATAA
AATTTTAAAATAATTCTAGTTATAAAATGTCCGAAGTTATAGTTTTCATT
GGAGCCCAATGGGGAGACGAAGGAAAAGGCAAGCTTGTAGACTTGTTTGC
TCAAGAGTGCGATGTGGTTTGCCGATGTCAAGGCGGCAATAATGCAGGTC
ATACTGTGATCGCGAACAATGTGAAATATGACTTTCATCTCTTACCTAGT
GGTATCTTACAAAAAGGAATAACAGCTGTAATTGGTAATGGAGTAGTTAT
CAATTTAAAGGATCTTATCAATGAAATTAATGTGAATATGAAAAAAGGAT
TATCTGATATCAAACAAAGATTAATTATATCAGATAGAGCTCATATCGTT
TTTGATTTGCATCAAATGATTGATGGATTACAAGAAGAGAAACGCGGTGG
GAGCATGATTGGTACAACTAAAAAAGGTATTGGACCAACATATTCATCAA
AAGCCACTAGAAATGGATTAAGGATTTGCGATCTTATCGGAGATTGGGGT
TTGTTTGAGGAAAAATATAAAAAACTCGTGTCATACATTTGTGCTCGTTA
TGGTGATGTGAAAATAGACGTTAAAAAAGATTTAGAGGAGCTTTATCTAT
ATCGGCAAGAACTTTCTCCAATGGTTAAAAACACTATTTTATGGCTTAAT
GAGAAATTGAAATCTGGAAAATCGAAAATTCTTGTCGAAGGAGCTCAGAG
CTGTATGTTGGATATAGATTTCGGTTCATATCCATATGTCACTTCATCCA
ATTGTTGTGTTGGTGGGGTATGCACTGGTCTTGGTTTGCCCCCGAGATCT
ATCTCGTCAGTTTTTGGCGTTATGAAAGCGTATACAACTCGTGTTGGTGT
TGGAGAGTTTCCCACAGAACTATTTGACGAAATAGGTGAGCACTTTCAAA
TAGTTGGCCATGAAATTGGAGTTACTACTCAAAGAAAGCGACGTACAGGT
TGGCTAGACACCGTTATGCTTCGATATGCTCATATGATCAATGGTTTTGA
AGCAGTCGGACTTACTAAATTAGATGTTCTGGATGAATTGGATGAAGTAA
AAGTTGGAAAGTGGTACGTAGACAAAAAGTCTGGTGAAATAATCAAAACA
TTCCCAGCCAATATGGATATATTAAAAAATATCGATGTTGAATATGAAGT
TCTGCCAGGATGGAAGAAATCGACAAAAAATTGTAGAGAATTTTCCGATT
TACCGAAAGAGGCTCAGGTATTTGTCGAGATTGTAGAAAAGCTAATAGGA
ATACCGATCCGTTGGATTGGTGTCGGTGCTGATAGGACTGATATCATTTA
CAGATCAGTTTGAAGTTTTATTATATCAGTTTTGCAGTGTGCAGTTTTTT
CTATGTAATGTGCTATTACATTTCTGCTTTAATTTTTGATTTTTTATCCA
TAGGTTTTGTTGTGTCTACTTAAATTTATCCTCAAATTAATAAATTCTAT
TTGGT
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protein sequence of SMED30003172-orf-1

>SMED30003172-orf-1 ID=SMED30003172-orf-1|Name=SMED30003172-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=429bp
MSEVIVFIGAQWGDEGKGKLVDLFAQECDVVCRCQGGNNAGHTVIANNVK
YDFHLLPSGILQKGITAVIGNGVVINLKDLINEINVNMKKGLSDIKQRLI
ISDRAHIVFDLHQMIDGLQEEKRGGSMIGTTKKGIGPTYSSKATRNGLRI
CDLIGDWGLFEEKYKKLVSYICARYGDVKIDVKKDLEELYLYRQELSPMV
KNTILWLNEKLKSGKSKILVEGAQSCMLDIDFGSYPYVTSSNCCVGGVCT
GLGLPPRSISSVFGVMKAYTTRVGVGEFPTELFDEIGEHFQIVGHEIGVT
TQRKRRTGWLDTVMLRYAHMINGFEAVGLTKLDVLDELDEVKVGKWYVDK
KSGEIIKTFPANMDILKNIDVEYEVLPGWKKSTKNCREFSDLPKEAQVFV
EIVEKLIGIPIRWIGVGADRTDIIYRSV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0000287magnesium ion binding
GO:0005525GTP binding
GO:0004019adenylosuccinate synthase activity
GO:0000166nucleotide binding
GO:0016874ligase activity
GO:0046872metal ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000035Category 3 cell
PLANA:0000429neoblast
PLANA:0002032epidermal cell
PLANA:0002056medial muscle cell
PLANA:0002142parenchyma
Vocabulary: INTERPRO
TermDefinition
IPR042110Adenylosuccinate_synth_dom2
IPR042111Adenylosuccinate_synth_dom3
IPR042109Adenylosuccinate_synth_dom1
IPR001114Adenylosuccinate_synthetase
IPR033128Adenylosuccin_syn_Lys_AS
IPR018220Adenylosuccin_syn_GTP-bd
IPR027417P-loop_NTPase
Vocabulary: biological process
TermDefinition
GO:0006164purine nucleotide biosynthetic process
GO:0006167AMP biosynthetic process
GO:0044208'de novo' AMP biosynthetic process
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001114Adenylosuccinate synthetaseSMARTSM00788adenylsucc_syntcoord: 4..425
e-value: 3.9E-226
score: 767.2
IPR001114Adenylosuccinate synthetasePFAMPF00709Adenylsucc_syntcoord: 6..424
e-value: 9.4E-168
score: 558.5
IPR001114Adenylosuccinate synthetaseTIGRFAMTIGR00184TIGR00184coord: 6..424
e-value: 1.8E-148
score: 492.9
IPR001114Adenylosuccinate synthetasePANTHERPTHR11846ADENYLOSUCCINATE SYNTHETASEcoord: 2..425
IPR001114Adenylosuccinate synthetaseCDDcd03108AdSScoord: 4..425
e-value: 4.01199E-171
score: 480.073
IPR042110Adenylosuccinate synthetase, domain 2GENE3DG3DSA:1.10.300.10coord: 103..199
e-value: 2.6E-104
score: 350.3
IPR042111Adenylosuccinate synthetase, domain 3GENE3DG3DSA:3.90.170.10coord: 266..428
e-value: 8.0E-62
score: 209.5
IPR042109Adenylosuccinate synthetase, domain 1GENE3DG3DSA:3.40.440.10coord: 8..259
e-value: 2.6E-104
score: 350.3
IPR033128Adenylosuccinate synthase, active sitePROSITEPS00513ADENYLOSUCCIN_SYN_2coord: 134..145
IPR018220Adenylosuccinate synthase, GTP-binding sitePROSITEPS01266ADENYLOSUCCIN_SYN_1coord: 11..18
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 3..426