slc4a-4
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30003166 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of slc4a-4 vs. Ensembl Human
Match: SLC4A11 (solute carrier family 4 member 11 [Source:HGNC Symbol;Acc:HGNC:16438]) HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0 Identity = 345/806 (42.80%), Postives = 506/806 (62.78%), Query Frame = 2
Query: 644 TADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQ--------MDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAE-------EQRLYRRRSIRITEVMNQAFAYEEKF-PLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVN-----KTVPIVNTTLAKGLLNST------NEFITITTE-----ESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFK-TRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
T +E G L+ + + +K+F E+RA D++ FL + ++L+ A +D ++ +LR A D + M T+A + K H L+ T++G+ G+ QSW+ +C++ + KRHV I+RL P N G +S V FV+LV+ P K K TK+ +E++RTFAT+ SD+ FR +LL +TE+EFKE L H R L R R ++ + + + F P G GI +D+ +R P+Y D+ DGI G + K ++ FLYFACLLP++AFG L D+NTDG I+V++ I Q++GGL +AL GQPL+++LTTAPL LYI+VI I Y L F + ++W G++NS FL LY+ +LS +M RSTEEI ALFISI F++DAVK +K+F+K Y ++ +T +V+ + LN++ F+ TE S + +L LL+++GT+WLG F K+P+L+ R +++D +LP+AVL S I S+ F++I++ F+ SE F++ +S+ AV A+GL F LS+LFF++QN+ +A+VN P N+L KG+AYHWDLL++AIIN LSLFGLPW+H PHSPLHV+ALA +EER+++GH IY+TIV V+ETRLT L + +L+GLSLLLLP+PL ++P VL GLF+Y+A+T+L GNQLV+RV LL EQ AYPP+HY+RRVPQRK+H FT LQ+ QL LLCA G + PY K+ FP++++ +PIR+ + P+ I Y+D +D
Sbjct: 80 TENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRR---FARDPDNNEPNCNLDLLMAMLFTDAGAPMRGKVHL-------LSDTIQGVTATVT-GVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALV-HQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAM--AQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGH-IYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMD 870
BLAST of slc4a-4 vs. Ensembl Human
Match: SLC4A11 (solute carrier family 4 member 11 [Source:HGNC Symbol;Acc:HGNC:16438]) HSP 1 Score: 553.518 bits (1425), Expect = 0.000e+0 Identity = 345/806 (42.80%), Postives = 506/806 (62.78%), Query Frame = 2
Query: 644 TADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQ--------MDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAE-------EQRLYRRRSIRITEVMNQAFAYEEKF-PLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVN-----KTVPIVNTTLAKGLLNST------NEFITITTE-----ESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFK-TRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
T +E G L+ + + +K+F E+RA D++ FL + ++L+ A +D ++ +LR A D + M T+A + K H L+ T++G+ G+ QSW+ +C++ + KRHV I+RL P N G +S V FV+LV+ P K K TK+ +E++RTFAT+ SD+ FR +LL +TE+EFKE L H R L R R ++ + + + F P G GI +D+ +R P+Y D+ DGI G + K ++ FLYFACLLP++AFG L D+NTDG I+V++ I Q++GGL +AL GQPL+++LTTAPL LYI+VI I Y L F + ++W G++NS FL LY+ +LS +M RSTEEI ALFISI F++DAVK +K+F+K Y ++ +T +V+ + LN++ F+ TE S + +L LL+++GT+WLG F K+P+L+ R +++D +LP+AVL S I S+ F++I++ F+ SE F++ +S+ AV A+GL F LS+LFF++QN+ +A+VN P N+L KG+AYHWDLL++AIIN LSLFGLPW+H PHSPLHV+ALA +EER+++GH IY+TIV V+ETRLT L + +L+GLSLLLLP+PL ++P VL GLF+Y+A+T+L GNQLV+RV LL EQ AYPP+HY+RRVPQRK+H FT LQ+ QL LLCA G + PY K+ FP++++ +PIR+ + P+ I Y+D +D
Sbjct: 123 TENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRR---FARDPDNNEPNCNLDLLMAMLFTDAGAPMRGKVHL-------LSDTIQGVTATVT-GVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALV-HQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAM--AQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGH-IYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMD 913
BLAST of slc4a-4 vs. Ensembl Human
Match: SLC4A11 (solute carrier family 4 member 11 [Source:HGNC Symbol;Acc:HGNC:16438]) HSP 1 Score: 553.132 bits (1424), Expect = 0.000e+0 Identity = 345/806 (42.80%), Postives = 506/806 (62.78%), Query Frame = 2
Query: 644 TADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQ--------MDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAE-------EQRLYRRRSIRITEVMNQAFAYEEKF-PLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVN-----KTVPIVNTTLAKGLLNST------NEFITITTE-----ESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFK-TRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
T +E G L+ + + +K+F E+RA D++ FL + ++L+ A +D ++ +LR A D + M T+A + K H L+ T++G+ G+ QSW+ +C++ + KRHV I+RL P N G +S V FV+LV+ P K K TK+ +E++RTFAT+ SD+ FR +LL +TE+EFKE L H R L R R ++ + + + F P G GI +D+ +R P+Y D+ DGI G + K ++ FLYFACLLP++AFG L D+NTDG I+V++ I Q++GGL +AL GQPL+++LTTAPL LYI+VI I Y L F + ++W G++NS FL LY+ +LS +M RSTEEI ALFISI F++DAVK +K+F+K Y ++ +T +V+ + LN++ F+ TE S + +L LL+++GT+WLG F K+P+L+ R +++D +LP+AVL S I S+ F++I++ F+ SE F++ +S+ AV A+GL F LS+LFF++QN+ +A+VN P N+L KG+AYHWDLL++AIIN LSLFGLPW+H PHSPLHV+ALA +EER+++GH IY+TIV V+ETRLT L + +L+GLSLLLLP+PL ++P VL GLF+Y+A+T+L GNQLV+RV LL EQ AYPP+HY+RRVPQRK+H FT LQ+ QL LLCA G + PY K+ FP++++ +PIR+ + P+ I Y+D +D
Sbjct: 96 TENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRR---FARDPDNNEPNCNLDLLMAMLFTDAGAPMRGKVHL-------LSDTIQGVTATVT-GVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALV-HQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAM--AQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGH-IYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMD 886
BLAST of slc4a-4 vs. Ensembl Human
Match: SLC4A11 (solute carrier family 4 member 11 [Source:HGNC Symbol;Acc:HGNC:16438]) HSP 1 Score: 534.643 bits (1376), Expect = 1.450e-174 Identity = 333/767 (43.42%), Postives = 486/767 (63.36%), Query Frame = 2
Query: 761 KEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQ--------MDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAE-------EQRLYRRRSIRITEVMNQAFAYEEKF-PLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVN-----KTVPIVNTTLAKGLLNST------NEFITITTE-----ESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFK-TRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
++ ++L+ A +D ++ +LR A D + M T+A + K H L+ T++G+ G+ QSW+ +C++ + KRHV I+RL P N G +S V FV+LV+ P K K TK+ +E++RTFAT+ SD+ FR +LL +TE+EFKE L H R L R R ++ + + + F P G GI +D+ +R P+Y D+ DGI G + K ++ FLYFACLLP++AFG L D+NTDG I+V++ I Q++GGL +AL GQPL+++LTTAPL LYI+VI I Y L F + ++W G++NS FL LY+ +LS +M RSTEEI ALFISI F++DAVK +K+F+K Y ++ +T +V+ + LN++ F+ TE S + +L LL+++GT+WLG F K+P+L+ R +++D +LP+AVL S I S+ F++I++ F+ SE F++ +S+ AV A+GL F LS+LFF++QN+ +A+VN P N+L KG+AYHWDLL++AIIN LSLFGLPW+H PHSPLHV+ALA +EER+++GH IY+TIV V+ETRLT L + +L+GLSLLLLP+PL ++P VL GLF+Y+A+T+L GNQLV+RV LL EQ AYPP+HY+RRVPQRK+H FT LQ+ QL LLCA G + PY K+ FP++++ +PIR+ + P+ I Y+D +D
Sbjct: 96 RKASIVLNETATSLDNVLRTMLRR---FARDPDNNEPNCNLDLLMAMLFTDAGAPMRGKVHL-------LSDTIQGVTATVT-GVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALV-HQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAM--AQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGH-IYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMD 847
BLAST of slc4a-4 vs. Ensembl Human
Match: SLC4A11 (solute carrier family 4 member 11 [Source:HGNC Symbol;Acc:HGNC:16438]) HSP 1 Score: 486.108 bits (1250), Expect = 3.796e-156 Identity = 324/806 (40.20%), Postives = 475/806 (58.93%), Query Frame = 2
Query: 644 TADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQ--------MDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAE-------EQRLYRRRSIRITEVMNQAFAYEEKF-PLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVN-----KTVPIVNTTLAKGLLNST------NEFITITTE-----ESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFK-TRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
T +E G L+ + + +K+F E+RA D++ FL + ++L+ A +D ++ +LR A D + M T+A + K H L+ T++G+ G+ QSW+ +C++ + KRHV I+RL P N G +S V FV+LV+ P K K TK+ +E++RTFAT+ SD+ FR +LL +TE+EFKE L H R L R R ++ + + + F P G GI +D+ +R P+Y D+ DGI G + K ++ FLYFACLLP++AFG L D+NTDG I VI I Y L F + ++W G++NS FL LY+ +LS +M RSTEEI ALFISI F++DAVK +K+F+K Y ++ +T +V+ + LN++ F+ TE S + +L LL+++GT+WLG F K+P+L+ R +++D +LP+AVL S I S+ F++I++ F+ SE F++ +S+ AV A+GL F LS+LFF++QN+ +A+VN P N+L KG+AYHWDLL++AIIN LSLFGLPW+H PHSPLHV+ALA +EER+++GH IY+TIV V+ETRLT L + +L+GLSLLLLP+PL ++P VL GLF+Y+A+T+L GNQLV+RV LL EQ AYPP+HY+RRVPQRK+H FT LQ+ QL LLCA G + PY K+ FP++++ +PIR+ + P+ I Y+D +D
Sbjct: 80 TENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRR---FARDPDNNEPNCNLDLLMAMLFTDAGAPMRGKVHL-------LSDTIQGVTATVT-GVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALV-HQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAI--------------------------------------VIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAM--AQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGH-IYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMD 832
BLAST of slc4a-4 vs. Ensembl Celegans
Match: abts-3 (Anion/Bicarbonate TranSporter family [Source:UniProtKB/TrEMBL;Acc:A0A3B1E4W4]) HSP 1 Score: 606.675 bits (1563), Expect = 0.000e+0 Identity = 376/870 (43.22%), Postives = 555/870 (63.79%), Query Frame = 2
Query: 410 VLTNCNQSPAIDRTNRRT-ISGLYNFKKQSTNND-DKDSKDRNLLLSPTNYINRQISETSEMSTDTVSNFSIGSLARYYRTADENGEGLP--CLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLS--TDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRR--SIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-------VTTLVNKTV--PIVNTTLAKGLLNSTNEFITI--TTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXX-XXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
V+T P I+ T + I +F STN D D S + L P R + M ++ S RY D+ + L+ A+ EKIP+KDF SE+RAT+D++ L + VL+LD++ ++ I ++ E MD+ Q F +E ++ N + L++T++ I + G S DQ+WI A+C L V RHVAIARL P NLGR+ + + F+++VI P + K TK+ +E +RTFATL +DME R +L+ AQ+ ++F+ L + A++LA +Q +R R SI ++ Q F E +P G+V++ ++R+ +Y SDY DGI+G T++KL S FLYFACLLP++AFGVL D NT G INV++VI++Q +GG+ F+L GGQP+I++LTT PL +YIKVI+ IS + F M++ VG+F +FLILYS +L LM+++TRS EE+F+LFI+IAF V++++ + F K+Y ++ +T N + A ++ + ++I T R++ +L++LL+ GT+WLG++ NF KTP+L S+R +ADY+LP +VLIMSF GSY F DI+ D F R E I+ + + + S F L L F LS LFF+DQN+TSA+VN NKLKKG++++ DL +VA++N+ LS+FGLPW+HG LPHSPLH++ALAD+EER+ GH ++E I+ VRETRL LI+H++I +S+ L PL +P +VL GLF+YMA+T+L GN++ ER++LL TEQ AYPP+HY+R+VPQRKVHLFT QL QL +LCA GF+P P+ ++ FPI+ +PIRH + P+ I Y+DALD
Sbjct: 21 VMTYNGTVPPIEITRSNSPIPSHAHFNLHSTNEDGDSGSLQHSFLRVPVGLSGRSSPSVASMGSEPESCIDD---TRYMTDDDDVIDEYDNVTLMYAKHEKIPMKDFGSEIRATMDIDHLLNKAVLLLDLQETSLEEIFAKIIHE-----MDI---QEPEFTSEQVRSVLFTQDAGN-QFHILSRTVQSICTTGSVGGSFDYDQTWICALCMLNTVQHRHVAIARLSHPTNLGRTMQDLRFIIIVIAPSRAKGTKTALETTRTFATLFADMEIRQRLVMAQSVEQFRSTLLSAAKELAMDQNQWRERKSSIHLSHAKEQIFGPEAWYPF-RGLVEEFKRRLAIYPSDYLDGIRGHKTVQKLFSTVVFLYFACLLPAIAFGVLNDDNTKGAINVRKVIIAQAIGGIFFSLFGGQPMIILLTTVPLAIYIKVIFKISQELGYDFLAMYACVGLFCQMFLILYSATELCSLMKFATRSAEEMFSLFIAIAFTVESIRAIHNSFKKNYNDCDTSAISMKAARTALNAFKNGSNADSIVGNITSSMSIGDTGSLCRRDTSILYMLLMFGTLWLGLFLYNFRKTPYLTRSRREWLADYALPASVLIMSFTGSYAFSDIEKDRFNLRFEFPL-IQMADVTSLPPSGYFVCLLLGFSLSFLFFIDQNITSAIVNNNQNKLKKGTSHNLDLFVVALLNMFLSVFGLPWMHGALPHSPLHLRALADVEERVSQGH-VHEVIMNVRETRLASLIAHVMILVSMFFLIPYPLQLIPTSVLHGLFLYMALTSLSGNEMFERLLLLITEQQAYPPTHYIRKVPQRKVHLFTACQLLQLIILCAFGFSPYPFIEMVFPIVCFFFLPIRHTLIPRLIDYKYLDALD 875
BLAST of slc4a-4 vs. Ensembl Celegans
Match: abts-3 (Anion/Bicarbonate TranSporter family [Source:UniProtKB/TrEMBL;Acc:A0A3B1E4W4]) HSP 1 Score: 605.52 bits (1560), Expect = 0.000e+0 Identity = 355/777 (45.69%), Postives = 524/777 (67.44%), Query Frame = 2
Query: 677 LVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLS--TDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRR--SIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-------VTTLVNKTV--PIVNTTLAKGLLNSTNEFITI--TTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXX-XXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
L+ A+ EKIP+KDF SE+RAT+D++ L + VL+LD++ ++ I ++ E MD+ Q F +E ++ N + L++T++ I + G S DQ+WI A+C L V RHVAIARL P NLGR+ + + F+++VI P + K TK+ +E +RTFATL +DME R +L+ AQ+ ++F+ L + A++LA +Q +R R SI ++ Q F E +P G+V++ ++R+ +Y SDY DGI+G T++KL S FLYFACLLP++AFGVL D NT G INV++VI++Q +GG+ F+L GGQP+I++LTT PL +YIKVI+ IS + F M++ VG+F +FLILYS +L LM+++TRS EE+F+LFI+IAF V++++ + F K+Y ++ +T N + A ++ + ++I T R++ +L++LL+ GT+WLG++ NF KTP+L S+R +ADY+LP +VLIMSF GSY F DI+ D F R E I+ + + + S F L L F LS LFF+DQN+TSA+VN NKLKKG++++ DL +VA++N+ LS+FGLPW+HG LPHSPLH++ALAD+EER+ GH ++E I+ VRETRL LI+H++I +S+ L PL +P +VL GLF+YMA+T+L GN++ ER++LL TEQ AYPP+HY+R+VPQRKVHLFT QL QL +LCA GF+P P+ ++ FPI+ +PIRH + P+ I Y+DALD
Sbjct: 192 LMYAKHEKIPMKDFGSEIRATMDIDHLLNKAVLLLDLQETSLEEIFAKIIHE-----MDI---QEPEFTSEQVRSVLFTQDAGN-QFHILSRTVQSICTTGSVGGSFDYDQTWICALCMLNTVQHRHVAIARLSHPTNLGRTMQDLRFIIIVIAPSRAKGTKTALETTRTFATLFADMEIRQRLVMAQSVEQFRSTLLSAAKELAMDQNQWRERKSSIHLSHAKEQIFGPEAWYPF-RGLVEEFKRRLAIYPSDYLDGIRGHKTVQKLFSTVVFLYFACLLPAIAFGVLNDDNTKGAINVRKVIIAQAIGGIFFSLFGGQPMIILLTTVPLAIYIKVIFKISQELGYDFLAMYACVGLFCQMFLILYSATELCSLMKFATRSAEEMFSLFIAIAFTVESIRAIHNSFKKNYNDCDTSAISMKAARTALNAFKNGSNADSIVGNITSSMSIGDTGSLCRRDTSILYMLLMFGTLWLGLFLYNFRKTPYLTRSRREWLADYALPASVLIMSFTGSYAFSDIEKDRFNLRFEFPL-IQMADVTSLPPSGYFVCLLLGFSLSFLFFIDQNITSAIVNNNQNKLKKGTSHNLDLFVVALLNMFLSVFGLPWMHGALPHSPLHLRALADVEERVSQGH-VHEVIMNVRETRLASLIAHVMILVSMFFLIPYPLQLIPTSVLHGLFLYMALTSLSGNEMFERLLLLITEQQAYPPTHYIRKVPQRKVHLFTACQLLQLIILCAFGFSPYPFIEMVFPIVCFFFLPIRHTLIPRLIDYKYLDALD 956
BLAST of slc4a-4 vs. Ensembl Celegans
Match: abts-3 (Anion/Bicarbonate TranSporter family [Source:UniProtKB/TrEMBL;Acc:A0A3B1E4W4]) HSP 1 Score: 603.979 bits (1556), Expect = 0.000e+0 Identity = 356/777 (45.82%), Postives = 526/777 (67.70%), Query Frame = 2
Query: 677 LVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLS--TDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRR--SIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-------VTTLVNKTV--PIVNTTLAKGLLNSTNEFITI--TTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXX-XXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
L+ A+ EKIP+KDF SE+RAT+D++ L + VL+LD++ ++ I ++ E MD+ Q F +E ++ N + L++T++ I + G S DQ+WI A+C L V RHVAIARL P NLGR+ + + F+++VI P + K TK+ +E +RTFATL +DME R +L+ AQ+ ++F+ L + A++LA +Q +R R SI ++ Q F E +P G+V++ ++R+ +Y SDY DGI+G T++KL S FLYFACLLP++AFGVL D NT G INV++VI++Q +GG+ F+L GGQP+I++LTT PL +YIKVI+ IS + F M++ VG+F +FLILYS +L LM+++TRS EE+F+LFI+IAF V++++ + F K+Y ++ +T N + A ++ + ++I T R++ +L++LL+ GT+WLG++ NF KTP+L S+R +ADY+LP +VLIMSF GSY F DI+ D F R E I+ + + + S F L L F LS LFF+DQN+TSA+VN NKLKKG++++ DL +VA++N+ LS+FGLPW+HG LPHSPLH++ALAD+EER+ GH ++E I+ VRETRL LI+H++I +S+ L+P PL +P +VL GLF+YMA+T+L GN++ ER++LL TEQ AYPP+HY+R+VPQRKVHLFT QL QL +LCA GF+P P+ ++ FPI+ +PIRH + P+ I Y+DALD
Sbjct: 276 LMYAKHEKIPMKDFGSEIRATMDIDHLLNKAVLLLDLQETSLEEIFAKIIHE-----MDI---QEPEFTSEQVRSVLFTQDAGN-QFHILSRTVQSICTTGSVGGSFDYDQTWICALCMLNTVQHRHVAIARLSHPTNLGRTMQDLRFIIIVIAPSRAKGTKTALETTRTFATLFADMEIRQRLVMAQSVEQFRSTLLSAAKELAMDQNQWRERKSSIHLSHAKEQIFGPEAWYPF-RGLVEEFKRRLAIYPSDYLDGIRGHKTVQKLFSTVVFLYFACLLPAIAFGVLNDDNTKGAINVRKVIIAQAIGGIFFSLFGGQPMIILLTTVPLAIYIKVIFKISQELGYDFLAMYACVGLFCQMFLILYSATELCSLMKFATRSAEEMFSLFIAIAFTVESIRAIHNSFKKNYNDCDTSAISMKAARTALNAFKNGSNADSIVGNITSSMSIGDTGSLCRRDTSILYMLLMFGTLWLGLFLYNFRKTPYLTRSRREWLADYALPASVLIMSFTGSYAFSDIEKDRFNLRFEFPL-IQMADVTSLPPSGYFVCLLLGFSLSFLFFIDQNITSAIVNNNQNKLKKGTSHNLDLFVVALLNMFLSVFGLPWMHGALPHSPLHLRALADVEERVSQGH-VHEVIMNVRETRLASLIAHVMILVSMFFLIPYPLQLIPTSVLHGLFLYMALTSLSGNEMFERLLLLITEQQAYPPTHYIRKVPQRKVHLFTACQLLQLIILCAFGFSPYPFIEMVFPIVCFFFLPIRHTLIPRLIDYKYLDALD 1040
BLAST of slc4a-4 vs. Ensembl Celegans
Match: abts-3 (Anion/Bicarbonate TranSporter family [Source:UniProtKB/TrEMBL;Acc:A0A3B1E4W4]) HSP 1 Score: 603.594 bits (1555), Expect = 0.000e+0 Identity = 355/777 (45.69%), Postives = 524/777 (67.44%), Query Frame = 2
Query: 677 LVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLS--TDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRR--SIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-------VTTLVNKTV--PIVNTTLAKGLLNSTNEFITI--TTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXX-XXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
L+ A+ EKIP+KDF SE+RAT+D++ L + VL+LD++ ++ I ++ E MD+ Q F +E ++ N + L++T++ I + G S DQ+WI A+C L V RHVAIARL P NLGR+ + + F+++VI P + K TK+ +E +RTFATL +DME R +L+ AQ+ ++F+ L + A++LA +Q +R R SI ++ Q F E +P G+V++ ++R+ +Y SDY DGI+G T++KL S FLYFACLLP++AFGVL D NT G INV++VI++Q +GG+ F+L GGQP+I++LTT PL +YIKVI+ IS + F M++ VG+F +FLILYS +L LM+++TRS EE+F+LFI+IAF V++++ + F K+Y ++ +T N + A ++ + ++I T R++ +L++LL+ GT+WLG++ NF KTP+L S+R +ADY+LP +VLIMSF GSY F DI+ D F R E I+ + + + S F L L F LS LFF+DQN+TSA+VN NKLKKG++++ DL +VA++N+ LS+FGLPW+HG LPHSPLH++ALAD+EER+ GH ++E I+ VRETRL LI+H++I +S+ L PL +P +VL GLF+YMA+T+L GN++ ER++LL TEQ AYPP+HY+R+VPQRKVHLFT QL QL +LCA GF+P P+ ++ FPI+ +PIRH + P+ I Y+DALD
Sbjct: 30 LMYAKHEKIPMKDFGSEIRATMDIDHLLNKAVLLLDLQETSLEEIFAKIIHE-----MDI---QEPEFTSEQVRSVLFTQDAGN-QFHILSRTVQSICTTGSVGGSFDYDQTWICALCMLNTVQHRHVAIARLSHPTNLGRTMQDLRFIIIVIAPSRAKGTKTALETTRTFATLFADMEIRQRLVMAQSVEQFRSTLLSAAKELAMDQNQWRERKSSIHLSHAKEQIFGPEAWYPF-RGLVEEFKRRLAIYPSDYLDGIRGHKTVQKLFSTVVFLYFACLLPAIAFGVLNDDNTKGAINVRKVIIAQAIGGIFFSLFGGQPMIILLTTVPLAIYIKVIFKISQELGYDFLAMYACVGLFCQMFLILYSATELCSLMKFATRSAEEMFSLFIAIAFTVESIRAIHNSFKKNYNDCDTSAISMKAARTALNAFKNGSNADSIVGNITSSMSIGDTGSLCRRDTSILYMLLMFGTLWLGLFLYNFRKTPYLTRSRREWLADYALPASVLIMSFTGSYAFSDIEKDRFNLRFEFPL-IQMADVTSLPPSGYFVCLLLGFSLSFLFFIDQNITSAIVNNNQNKLKKGTSHNLDLFVVALLNMFLSVFGLPWMHGALPHSPLHLRALADVEERVSQGH-VHEVIMNVRETRLASLIAHVMILVSMFFLIPYPLQLIPTSVLHGLFLYMALTSLSGNEMFERLLLLITEQQAYPPTHYIRKVPQRKVHLFTACQLLQLIILCAFGFSPYPFIEMVFPIVCFFFLPIRHTLIPRLIDYKYLDALD 794
BLAST of slc4a-4 vs. Ensembl Celegans
Match: abts-3 (Anion/Bicarbonate TranSporter family [Source:UniProtKB/TrEMBL;Acc:A0A3B1E4W4]) HSP 1 Score: 603.208 bits (1554), Expect = 0.000e+0 Identity = 355/777 (45.69%), Postives = 524/777 (67.44%), Query Frame = 2
Query: 677 LVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLS--TDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRR--SIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-------VTTLVNKTV--PIVNTTLAKGLLNSTNEFITI--TTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXX-XXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
L+ A+ EKIP+KDF SE+RAT+D++ L + VL+LD++ ++ I ++ E MD+ Q F +E ++ N + L++T++ I + G S DQ+WI A+C L V RHVAIARL P NLGR+ + + F+++VI P + K TK+ +E +RTFATL +DME R +L+ AQ+ ++F+ L + A++LA +Q +R R SI ++ Q F E +P G+V++ ++R+ +Y SDY DGI+G T++KL S FLYFACLLP++AFGVL D NT G INV++VI++Q +GG+ F+L GGQP+I++LTT PL +YIKVI+ IS + F M++ VG+F +FLILYS +L LM+++TRS EE+F+LFI+IAF V++++ + F K+Y ++ +T N + A ++ + ++I T R++ +L++LL+ GT+WLG++ NF KTP+L S+R +ADY+LP +VLIMSF GSY F DI+ D F R E I+ + + + S F L L F LS LFF+DQN+TSA+VN NKLKKG++++ DL +VA++N+ LS+FGLPW+HG LPHSPLH++ALAD+EER+ GH ++E I+ VRETRL LI+H++I +S+ L PL +P +VL GLF+YMA+T+L GN++ ER++LL TEQ AYPP+HY+R+VPQRKVHLFT QL QL +LCA GF+P P+ ++ FPI+ +PIRH + P+ I Y+DALD
Sbjct: 123 LMYAKHEKIPMKDFGSEIRATMDIDHLLNKAVLLLDLQETSLEEIFAKIIHE-----MDI---QEPEFTSEQVRSVLFTQDAGN-QFHILSRTVQSICTTGSVGGSFDYDQTWICALCMLNTVQHRHVAIARLSHPTNLGRTMQDLRFIIIVIAPSRAKGTKTALETTRTFATLFADMEIRQRLVMAQSVEQFRSTLLSAAKELAMDQNQWRERKSSIHLSHAKEQIFGPEAWYPF-RGLVEEFKRRLAIYPSDYLDGIRGHKTVQKLFSTVVFLYFACLLPAIAFGVLNDDNTKGAINVRKVIIAQAIGGIFFSLFGGQPMIILLTTVPLAIYIKVIFKISQELGYDFLAMYACVGLFCQMFLILYSATELCSLMKFATRSAEEMFSLFIAIAFTVESIRAIHNSFKKNYNDCDTSAISMKAARTALNAFKNGSNADSIVGNITSSMSIGDTGSLCRRDTSILYMLLMFGTLWLGLFLYNFRKTPYLTRSRREWLADYALPASVLIMSFTGSYAFSDIEKDRFNLRFEFPL-IQMADVTSLPPSGYFVCLLLGFSLSFLFFIDQNITSAIVNNNQNKLKKGTSHNLDLFVVALLNMFLSVFGLPWMHGALPHSPLHLRALADVEERVSQGH-VHEVIMNVRETRLASLIAHVMILVSMFFLIPYPLQLIPTSVLHGLFLYMALTSLSGNEMFERLLLLITEQQAYPPTHYIRKVPQRKVHLFTACQLLQLIILCAFGFSPYPFIEMVFPIVCFFFLPIRHTLIPRLIDYKYLDALD 887
BLAST of slc4a-4 vs. Ensembl Fly
Match: CG8177 (gene:FBgn0036043 transcript:FBtr0076326) HSP 1 Score: 176.022 bits (445), Expect = 2.082e-44 Identity = 144/540 (26.67%), Postives = 266/540 (49.26%), Query Frame = 2
Query: 1370 LGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIV---NTTLAKGLLNSTNEFITITTE------------------ESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDI---KIDTFKTRSEEEFSIK--FVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRH 2911
L G+ +DL++R+P+Y SD DG+ + ++A F+YFACL ++ FG L T+ I + ++S ++ G+ F + QPL+++ TT PL L+ + + ++ F ++ +VG++ I + S + S +R TR T+EIF+ I++ +IV+ ++ ++ ++ + + N P + + LLN+T T T+ +++ L +L + T + Y F + FL + R + D+ +P+++ I + YL + K+ + S + S + ++ F S FA + A + +L FM+ ++ +V+ P LKKGS HWD++++ ++N +FG+PW S HV ++ + G IV V+E R L+ +L+ L +P+AVL G+F+YM + ++ G QL ER+ L F YPP+ Y++R+ K+HLFT +Q+ L LL ++ + + FP L++ +PIR
Sbjct: 602 LWGGLRNDLKRRMPMYKSDILDGLNT-----ETLAATIFMYFACLSTAITFGGLVSAKTNSWIGISETLISCSLVGIVFHCLSCQPLVIIGTTGPLLLFDEALMVFCTQHEFDFLSLRVYVGVWLIIIALTVSAFEGSVYVRLLTRFTQEIFSALITLIYIVETFMKLISIYRENPLLSDYNLPPPTLVAHEHATNESLLNATASVTTNITQMVMNISTTAMPIGPPPLPKNQPNTALFCTILTLATFVVAYYLKLFRNSHFLGRNARRALGDFGVPISIAIFVLV-DYLVPAVYTEKLVVPEGLSPSDPSKRGWYIGFDTSSTWIPFACVIPALLVYILIFMESQISELIVDKPDRGLKKGSGLHWDIVLLCLLNCACGIFGMPWHCAATVRSVTHVSSVTIMSRTHAPGES--PRIVDVKEQR-LSGFFVCLMIGLSVLMAPLLRLIPMAVLFGVFLYMGVASMSGVQLFERIRLYFMPVKHYPPTSYVKRLRPWKLHLFTTIQVLCLVLLWSVKSS---QFSLAFPFFLIMMVPIRQ 1129
BLAST of slc4a-4 vs. Ensembl Fly
Match: CG8177 (gene:FBgn0036043 transcript:FBtr0076322) HSP 1 Score: 176.022 bits (445), Expect = 2.292e-44 Identity = 144/540 (26.67%), Postives = 266/540 (49.26%), Query Frame = 2
Query: 1370 LGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIV---NTTLAKGLLNSTNEFITITTE------------------ESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDI---KIDTFKTRSEEEFSIK--FVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRH 2911
L G+ +DL++R+P+Y SD DG+ + ++A F+YFACL ++ FG L T+ I + ++S ++ G+ F + QPL+++ TT PL L+ + + ++ F ++ +VG++ I + S + S +R TR T+EIF+ I++ +IV+ ++ ++ ++ + + N P + + LLN+T T T+ +++ L +L + T + Y F + FL + R + D+ +P+++ I + YL + K+ + S + S + ++ F S FA + A + +L FM+ ++ +V+ P LKKGS HWD++++ ++N +FG+PW S HV ++ + G IV V+E R L+ +L+ L +P+AVL G+F+YM + ++ G QL ER+ L F YPP+ Y++R+ K+HLFT +Q+ L LL ++ + + FP L++ +PIR
Sbjct: 597 LWGGLRNDLKRRMPMYKSDILDGLNT-----ETLAATIFMYFACLSTAITFGGLVSAKTNSWIGISETLISCSLVGIVFHCLSCQPLVIIGTTGPLLLFDEALMVFCTQHEFDFLSLRVYVGVWLIIIALTVSAFEGSVYVRLLTRFTQEIFSALITLIYIVETFMKLISIYRENPLLSDYNLPPPTLVAHEHATNESLLNATASVTTNITQMVMNISTTAMPIGPPPLPKNQPNTALFCTILTLATFVVAYYLKLFRNSHFLGRNARRALGDFGVPISIAIFVLV-DYLVPAVYTEKLVVPEGLSPSDPSKRGWYIGFDTSSTWIPFACVIPALLVYILIFMESQISELIVDKPDRGLKKGSGLHWDIVLLCLLNCACGIFGMPWHCAATVRSVTHVSSVTIMSRTHAPGES--PRIVDVKEQR-LSGFFVCLMIGLSVLMAPLLRLIPMAVLFGVFLYMGVASMSGVQLFERIRLYFMPVKHYPPTSYVKRLRPWKLHLFTTIQVLCLVLLWSVKSS---QFSLAFPFFLIMMVPIRQ 1124
BLAST of slc4a-4 vs. Ensembl Fly
Match: CG8177 (gene:FBgn0036043 transcript:FBtr0076327) HSP 1 Score: 175.637 bits (444), Expect = 3.288e-44 Identity = 144/540 (26.67%), Postives = 266/540 (49.26%), Query Frame = 2
Query: 1370 LGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIV---NTTLAKGLLNSTNEFITITTE------------------ESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDI---KIDTFKTRSEEEFSIK--FVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRH 2911
L G+ +DL++R+P+Y SD DG+ + ++A F+YFACL ++ FG L T+ I + ++S ++ G+ F + QPL+++ TT PL L+ + + ++ F ++ +VG++ I + S + S +R TR T+EIF+ I++ +IV+ ++ ++ ++ + + N P + + LLN+T T T+ +++ L +L + T + Y F + FL + R + D+ +P+++ I + YL + K+ + S + S + ++ F S FA + A + +L FM+ ++ +V+ P LKKGS HWD++++ ++N +FG+PW S HV ++ + G IV V+E R L+ +L+ L +P+AVL G+F+YM + ++ G QL ER+ L F YPP+ Y++R+ K+HLFT +Q+ L LL ++ + + FP L++ +PIR
Sbjct: 669 LWGGLRNDLKRRMPMYKSDILDGLNT-----ETLAATIFMYFACLSTAITFGGLVSAKTNSWIGISETLISCSLVGIVFHCLSCQPLVIIGTTGPLLLFDEALMVFCTQHEFDFLSLRVYVGVWLIIIALTVSAFEGSVYVRLLTRFTQEIFSALITLIYIVETFMKLISIYRENPLLSDYNLPPPTLVAHEHATNESLLNATASVTTNITQMVMNISTTAMPIGPPPLPKNQPNTALFCTILTLATFVVAYYLKLFRNSHFLGRNARRALGDFGVPISIAIFVLV-DYLVPAVYTEKLVVPEGLSPSDPSKRGWYIGFDTSSTWIPFACVIPALLVYILIFMESQISELIVDKPDRGLKKGSGLHWDIVLLCLLNCACGIFGMPWHCAATVRSVTHVSSVTIMSRTHAPGES--PRIVDVKEQR-LSGFFVCLMIGLSVLMAPLLRLIPMAVLFGVFLYMGVASMSGVQLFERIRLYFMPVKHYPPTSYVKRLRPWKLHLFTTIQVLCLVLLWSVKSS---QFSLAFPFFLIMMVPIRQ 1196
BLAST of slc4a-4 vs. Ensembl Fly
Match: CG8177 (gene:FBgn0036043 transcript:FBtr0076325) HSP 1 Score: 175.252 bits (443), Expect = 3.437e-44 Identity = 144/540 (26.67%), Postives = 266/540 (49.26%), Query Frame = 2
Query: 1370 LGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIV---NTTLAKGLLNSTNEFITITTE------------------ESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDI---KIDTFKTRSEEEFSIK--FVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRH 2911
L G+ +DL++R+P+Y SD DG+ + ++A F+YFACL ++ FG L T+ I + ++S ++ G+ F + QPL+++ TT PL L+ + + ++ F ++ +VG++ I + S + S +R TR T+EIF+ I++ +IV+ ++ ++ ++ + + N P + + LLN+T T T+ +++ L +L + T + Y F + FL + R + D+ +P+++ I + YL + K+ + S + S + ++ F S FA + A + +L FM+ ++ +V+ P LKKGS HWD++++ ++N +FG+PW S HV ++ + G IV V+E R L+ +L+ L +P+AVL G+F+YM + ++ G QL ER+ L F YPP+ Y++R+ K+HLFT +Q+ L LL ++ + + FP L++ +PIR
Sbjct: 637 LWGGLRNDLKRRMPMYKSDILDGLNT-----ETLAATIFMYFACLSTAITFGGLVSAKTNSWIGISETLISCSLVGIVFHCLSCQPLVIIGTTGPLLLFDEALMVFCTQHEFDFLSLRVYVGVWLIIIALTVSAFEGSVYVRLLTRFTQEIFSALITLIYIVETFMKLISIYRENPLLSDYNLPPPTLVAHEHATNESLLNATASVTTNITQMVMNISTTAMPIGPPPLPKNQPNTALFCTILTLATFVVAYYLKLFRNSHFLGRNARRALGDFGVPISIAIFVLV-DYLVPAVYTEKLVVPEGLSPSDPSKRGWYIGFDTSSTWIPFACVIPALLVYILIFMESQISELIVDKPDRGLKKGSGLHWDIVLLCLLNCACGIFGMPWHCAATVRSVTHVSSVTIMSRTHAPGES--PRIVDVKEQR-LSGFFVCLMIGLSVLMAPLLRLIPMAVLFGVFLYMGVASMSGVQLFERIRLYFMPVKHYPPTSYVKRLRPWKLHLFTTIQVLCLVLLWSVKSS---QFSLAFPFFLIMMVPIRQ 1164
BLAST of slc4a-4 vs. Ensembl Fly
Match: CG8177 (gene:FBgn0036043 transcript:FBtr0076324) HSP 1 Score: 175.252 bits (443), Expect = 3.437e-44 Identity = 144/540 (26.67%), Postives = 266/540 (49.26%), Query Frame = 2
Query: 1370 LGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIV---NTTLAKGLLNSTNEFITITTE------------------ESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDI---KIDTFKTRSEEEFSIK--FVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRH 2911
L G+ +DL++R+P+Y SD DG+ + ++A F+YFACL ++ FG L T+ I + ++S ++ G+ F + QPL+++ TT PL L+ + + ++ F ++ +VG++ I + S + S +R TR T+EIF+ I++ +IV+ ++ ++ ++ + + N P + + LLN+T T T+ +++ L +L + T + Y F + FL + R + D+ +P+++ I + YL + K+ + S + S + ++ F S FA + A + +L FM+ ++ +V+ P LKKGS HWD++++ ++N +FG+PW S HV ++ + G IV V+E R L+ +L+ L +P+AVL G+F+YM + ++ G QL ER+ L F YPP+ Y++R+ K+HLFT +Q+ L LL ++ + + FP L++ +PIR
Sbjct: 637 LWGGLRNDLKRRMPMYKSDILDGLNT-----ETLAATIFMYFACLSTAITFGGLVSAKTNSWIGISETLISCSLVGIVFHCLSCQPLVIIGTTGPLLLFDEALMVFCTQHEFDFLSLRVYVGVWLIIIALTVSAFEGSVYVRLLTRFTQEIFSALITLIYIVETFMKLISIYRENPLLSDYNLPPPTLVAHEHATNESLLNATASVTTNITQMVMNISTTAMPIGPPPLPKNQPNTALFCTILTLATFVVAYYLKLFRNSHFLGRNARRALGDFGVPISIAIFVLV-DYLVPAVYTEKLVVPEGLSPSDPSKRGWYIGFDTSSTWIPFACVIPALLVYILIFMESQISELIVDKPDRGLKKGSGLHWDIVLLCLLNCACGIFGMPWHCAATVRSVTHVSSVTIMSRTHAPGES--PRIVDVKEQR-LSGFFVCLMIGLSVLMAPLLRLIPMAVLFGVFLYMGVASMSGVQLFERIRLYFMPVKHYPPTSYVKRLRPWKLHLFTTIQVLCLVLLWSVKSS---QFSLAFPFFLIMMVPIRQ 1164
BLAST of slc4a-4 vs. Ensembl Zebrafish
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 478.404 bits (1230), Expect = 1.119e-153 Identity = 306/786 (38.93%), Postives = 495/786 (62.98%), Query Frame = 2
Query: 635 YYRTADENGEGLP-CLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQ-AFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-VTTLVNKTVPIVN---TTLAKGLLNSTNEFITITTEES----RKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
Y + G G C+ + + + +F EVRA D++ FL+ ++L + +D +++ +LR + + D + E ++LF A + + L++TL+ + G+ QSW+ +C++ + +RHV I+RL P N G + V +V+L++ P K K TK+ +EL RTFA++ SD+ FR +LL ++T++EFKE L L +R T+ +Q + F +G GI +DL +R+P+Y SD+ DG+ G + K ++ + FLY A LLP++AFG L D++T G+I+V++ I+ Q++GG+ ++L G PL++ LTTAP+ ++I VI I Y L F ++ +G++NS+FLI+ + +LS L++ RS EE+ ALFISIAF+ DAVK +K+F+ +Y TL N + +N ++ G LN T E ++ ES + LL LLL++GT+W+G F ++PFL+ R +++D +LP++VL+ S++GSY+F DI + F F + ++ +++ ++V +A+GL F L LL F+DQN+ ++ N P N+L KG+AYHWDL + +IN+++S+ GLPW+H PHS LHV+ LA +EER++ GH +YETIV V+ETR+T L+++ILIG+S+ LLP+PL ++P VL GLF+Y+A+T++ GNQ+ +R+ LL EQ +YPP+HY+R+VPQRK+H FT LQ+ QL LCA G P PY K+ FP+L+ + +PIR+ + P+ I Y+D +D
Sbjct: 37 YGSQTHQGGPGQRVCVFASGFRYVKLMNFEEEVRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHV---SQDPHTAEPGCNFEEIMSSLFTDAGSQEVNVHLLSETLQCVTATAT-GIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPSKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHLTAAKRKTTAVEGEETDPHSQKPLKCRDFFRVGRGIYEDLCRRLPLYPSDFTDGLVGNNKALVKFMTTSIFLYIAVLLPAIAFGSLNDESTRGEIDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIMGGVFNLSLLVKLFKRSIEEVIALFISIAFVADAVKGTVKIFHDNYHAPTLANGSAAELNRISGSVHLGELNQT-EAGPVSLPESFILCTRARPLLCLLLMMGTLWVGYTLYQFRRSPFLHVKMREILSDCALPISVLVFSYVGSYVFNDIALPVFNFHEGPVFQVAPLD--KLTGASVLSAMGLGFLLFLLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGH-LYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIEGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCAFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIEAKYLDIMD 814
BLAST of slc4a-4 vs. Ensembl Zebrafish
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 478.404 bits (1230), Expect = 1.119e-153 Identity = 306/786 (38.93%), Postives = 495/786 (62.98%), Query Frame = 2
Query: 635 YYRTADENGEGLP-CLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQ-AFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-VTTLVNKTVPIVN---TTLAKGLLNSTNEFITITTEES----RKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
Y + G G C+ + + + +F EVRA D++ FL+ ++L + +D +++ +LR + + D + E ++LF A + + L++TL+ + G+ QSW+ +C++ + +RHV I+RL P N G + V +V+L++ P K K TK+ +EL RTFA++ SD+ FR +LL ++T++EFKE L L +R T+ +Q + F +G GI +DL +R+P+Y SD+ DG+ G + K ++ + FLY A LLP++AFG L D++T G+I+V++ I+ Q++GG+ ++L G PL++ LTTAP+ ++I VI I Y L F ++ +G++NS+FLI+ + +LS L++ RS EE+ ALFISIAF+ DAVK +K+F+ +Y TL N + +N ++ G LN T E ++ ES + LL LLL++GT+W+G F ++PFL+ R +++D +LP++VL+ S++GSY+F DI + F F + ++ +++ ++V +A+GL F L LL F+DQN+ ++ N P N+L KG+AYHWDL + +IN+++S+ GLPW+H PHS LHV+ LA +EER++ GH +YETIV V+ETR+T L+++ILIG+S+ LLP+PL ++P VL GLF+Y+A+T++ GNQ+ +R+ LL EQ +YPP+HY+R+VPQRK+H FT LQ+ QL LCA G P PY K+ FP+L+ + +PIR+ + P+ I Y+D +D
Sbjct: 37 YGSQTHQGGPGQRVCVFASGFRYVKLMNFEEEVRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHV---SQDPHTAEPGCNFEEIMSSLFTDAGSQEVNVHLLSETLQCVTATAT-GIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPSKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHLTAAKRKTTAVEGEETDPHSQKPLKCRDFFRVGRGIYEDLCRRLPLYPSDFTDGLVGNNKALVKFMTTSIFLYIAVLLPAIAFGSLNDESTRGEIDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIMGGVFNLSLLVKLFKRSIEEVIALFISIAFVADAVKGTVKIFHDNYHAPTLANGSAAELNRISGSVHLGELNQT-EAGPVSLPESFILCTRARPLLCLLLMMGTLWVGYTLYQFRRSPFLHVKMREILSDCALPISVLVFSYVGSYVFNDIALPVFNFHEGPVFQVAPLD--KLTGASVLSAMGLGFLLFLLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGH-LYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIEGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCAFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIEAKYLDIMD 814
BLAST of slc4a-4 vs. Ensembl Zebrafish
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 476.478 bits (1225), Expect = 2.409e-153 Identity = 302/763 (39.58%), Postives = 488/763 (63.96%), Query Frame = 2
Query: 701 IPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQ-AFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-VTTLVNKTVPIVN---TTLAKGLLNSTNEFITITTEES----RKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
+ + +F EVRA D++ FL+ ++L + +D +++ +LR + + D + E ++LF A + + L++TL+ + G+ QSW+ +C++ + +RHV I+RL P N G + V +V+L++ P K K TK+ +EL RTFA++ SD+ FR +LL ++T++EFKE L L +R T+ +Q + F +G GI +DL +R+P+Y SD+ DG+ G + K ++ + FLY A LLP++AFG L D++T G+I+V++ I+ Q++GG+ ++L G PL++ LTTAP+ ++I VI I Y L F ++ +G++NS+FLI+ + +LS L++ RS EE+ ALFISIAF+ DAVK +K+F+ +Y TL N + +N ++ G LN T E ++ ES + LL LLL++GT+W+G F ++PFL+ R +++D +LP++VL+ S++GSY+F DI + F F + ++ +++ ++V +A+GL F L LL F+DQN+ ++ N P N+L KG+AYHWDL + +IN+++S+ GLPW+H PHS LHV+ LA +EER++ GH +YETIV V+ETR+T L+++ILIG+S+ LLP+PL ++P VL GLF+Y+A+T++ GNQ+ +R+ LL EQ +YPP+HY+R+VPQRK+H FT LQ+ QL LCA G P PY K+ FP+L+ + +PIR+ + P+ I Y+D +D
Sbjct: 24 VKLMNFEEEVRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHV---SQDPHTAEPGCNFEEIMSSLFTDAGSQEVNVHLLSETLQCVTATAT-GIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPSKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHLTAAKRKTTAVEGEETDPHSQKPLKCRDFFRVGRGIYEDLCRRLPLYPSDFTDGLVGNNKALVKFMTTSIFLYIAVLLPAIAFGSLNDESTRGEIDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIMGGVFNLSLLVKLFKRSIEEVIALFISIAFVADAVKGTVKIFHDNYHAPTLANGSAAELNRISGSVHLGELNQT-EAGPVSLPESFILCTRARPLLCLLLMMGTLWVGYTLYQFRRSPFLHVKMREILSDCALPISVLVFSYVGSYVFNDIALPVFNFHEGPVFQVAPLD--KLTGASVLSAMGLGFLLFLLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGH-LYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIEGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCAFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIEAKYLDIMD 778
BLAST of slc4a-4 vs. Ensembl Zebrafish
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 476.478 bits (1225), Expect = 2.409e-153 Identity = 302/763 (39.58%), Postives = 488/763 (63.96%), Query Frame = 2
Query: 701 IPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQ-AFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-VTTLVNKTVPIVN---TTLAKGLLNSTNEFITITTEES----RKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
+ + +F EVRA D++ FL+ ++L + +D +++ +LR + + D + E ++LF A + + L++TL+ + G+ QSW+ +C++ + +RHV I+RL P N G + V +V+L++ P K K TK+ +EL RTFA++ SD+ FR +LL ++T++EFKE L L +R T+ +Q + F +G GI +DL +R+P+Y SD+ DG+ G + K ++ + FLY A LLP++AFG L D++T G+I+V++ I+ Q++GG+ ++L G PL++ LTTAP+ ++I VI I Y L F ++ +G++NS+FLI+ + +LS L++ RS EE+ ALFISIAF+ DAVK +K+F+ +Y TL N + +N ++ G LN T E ++ ES + LL LLL++GT+W+G F ++PFL+ R +++D +LP++VL+ S++GSY+F DI + F F + ++ +++ ++V +A+GL F L LL F+DQN+ ++ N P N+L KG+AYHWDL + +IN+++S+ GLPW+H PHS LHV+ LA +EER++ GH +YETIV V+ETR+T L+++ILIG+S+ LLP+PL ++P VL GLF+Y+A+T++ GNQ+ +R+ LL EQ +YPP+HY+R+VPQRK+H FT LQ+ QL LCA G P PY K+ FP+L+ + +PIR+ + P+ I Y+D +D
Sbjct: 24 VKLMNFEEEVRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHV---SQDPHTAEPGCNFEEIMSSLFTDAGSQEVNVHLLSETLQCVTATAT-GIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPSKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHLTAAKRKTTAVEGEETDPHSQKPLKCRDFFRVGRGIYEDLCRRLPLYPSDFTDGLVGNNKALVKFMTTSIFLYIAVLLPAIAFGSLNDESTRGEIDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIMGGVFNLSLLVKLFKRSIEEVIALFISIAFVADAVKGTVKIFHDNYHAPTLANGSAAELNRISGSVHLGELNQT-EAGPVSLPESFILCTRARPLLCLLLMMGTLWVGYTLYQFRRSPFLHVKMREILSDCALPISVLVFSYVGSYVFNDIALPVFNFHEGPVFQVAPLD--KLTGASVLSAMGLGFLLFLLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGH-LYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIEGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCAFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIEAKYLDIMD 778
BLAST of slc4a-4 vs. Ensembl Zebrafish
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 476.863 bits (1226), Expect = 9.330e-153 Identity = 302/763 (39.58%), Postives = 488/763 (63.96%), Query Frame = 2
Query: 701 IPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQ-AFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-VTTLVNKTVPIVN---TTLAKGLLNSTNEFITITTEES----RKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
+ + +F EVRA D++ FL+ ++L + +D +++ +LR + + D + E ++LF A + + L++TL+ + G+ QSW+ +C++ + +RHV I+RL P N G + V +V+L++ P K K TK+ +EL RTFA++ SD+ FR +LL ++T++EFKE L L +R T+ +Q + F +G GI +DL +R+P+Y SD+ DG+ G + K ++ + FLY A LLP++AFG L D++T G+I+V++ I+ Q++GG+ ++L G PL++ LTTAP+ ++I VI I Y L F ++ +G++NS+FLI+ + +LS L++ RS EE+ ALFISIAF+ DAVK +K+F+ +Y TL N + +N ++ G LN T E ++ ES + LL LLL++GT+W+G F ++PFL+ R +++D +LP++VL+ S++GSY+F DI + F F + ++ +++ ++V +A+GL F L LL F+DQN+ ++ N P N+L KG+AYHWDL + +IN+++S+ GLPW+H PHS LHV+ LA +EER++ GH +YETIV V+ETR+T L+++ILIG+S+ LLP+PL ++P VL GLF+Y+A+T++ GNQ+ +R+ LL EQ +YPP+HY+R+VPQRK+H FT LQ+ QL LCA G P PY K+ FP+L+ + +PIR+ + P+ I Y+D +D
Sbjct: 88 VKLMNFEEEVRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHV---SQDPHTAEPGCNFEEIMSSLFTDAGSQEVNVHLLSETLQCVTATAT-GIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPSKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHLTAAKRKTTAVEGEETDPHSQKPLKCRDFFRVGRGIYEDLCRRLPLYPSDFTDGLVGNNKALVKFMTTSIFLYIAVLLPAIAFGSLNDESTRGEIDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIMGGVFNLSLLVKLFKRSIEEVIALFISIAFVADAVKGTVKIFHDNYHAPTLANGSAAELNRISGSVHLGELNQT-EAGPVSLPESFILCTRARPLLCLLLMMGTLWVGYTLYQFRRSPFLHVKMREILSDCALPISVLVFSYVGSYVFNDIALPVFNFHEGPVFQVAPLD--KLTGASVLSAMGLGFLLFLLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGH-LYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIEGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCAFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIEAKYLDIMD 842
BLAST of slc4a-4 vs. Ensembl Xenopus
Match: SLC4A11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:100486382]) HSP 1 Score: 505.368 bits (1300), Expect = 4.185e-163 Identity = 331/807 (41.02%), Postives = 485/807 (60.10%), Query Frame = 2
Query: 644 TADENGEGLPCLVLARLEK-IPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIY--PLAMDVSIG---QMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLF---------AQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVT---------TLVNKTVPIVNTTLAKGLLNSTNEFITITTEESR--------KENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFK-TRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSP-LHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
TA+ G C++L K + +K+F EVRA D++ FL + +ILD A +D ++ +L+ P + S M T T++ H L+ T++G+ G+ QSW+ +C++ + KRHV I+RL+ P N G +S V FV+LV+ P K K TK+ E+ RTF+T+ SD+ FR +LL A L N L + ++ + +++ E N +G GI DD+ +R+PVY D+ DGI G I K ++ FLYFACLLPS+AFG L D++T G I+V++ I+ Q +GG+ ++L GQPL+V+LTTAPL LYI VI I Y+L F ++W G++NS FLILYSL + S LM+ RSTEEI ALFISI F++DA+K ++K+F K Y+ NK +P +N T + LLNST S +E+ +L L+L+ GT+WLG F K+P+L+S R +++D +LP++VL S +GSY FK+I I F ++E F + + + + + +A+GL F LS+LFF++QN+ +++ N P N+L KG+AYHWDLL+VA+IN LS+FG+PW+H HS A + +GH IYETIV VRETRLT L++++L+GLSL LLP PL ++P VL GLF+Y+A+T++ G+QL ERV LL EQ AYPP+HY+RRVPQRK+H FT LQ+ QL +LC G +P PY K+ FP++++ +PIR+ + PK I Y+DA+D
Sbjct: 82 TAENESSG--CVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAKASIILDETATSLDDVLREMLKHFVEDPENAEPSCNFNKIMSTLFTDSGAPREGNVHL-------LSDTIQGVTATAT-GVQYQQSWLCIICTIKSLQKRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFSTMFSDINFRQKLLETKTEEEFKEALVHQRHLLTLVNKHSSLNDGHKVQSHKPLKLNEFFN----------VGKGIFDDIARRLPVYPLDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDESTAGVIDVQKTIVGQCIGGVIYSLFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFKAFYAWTGLWNSCFLILYSLFNCSLLMKLFKRSTEEIIALFISITFVLDALKGIIKIFKKYYLEIPSSHTYPDQEYNKHLPNLNFT-SDVLLNSTFNGSVFAPNGSSDHEEIHYGRESAVLSLMLMFGTLWLGHTLYQFKKSPYLHSRVREMLSDCALPISVLTFSVVGSYFFKEIHIAKFNYIKTESMFVLAPIG--SLPMGPITSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSVFGMPWIHAAFLHSHNARAGARQSWKREWSTGH-IYETIVSVRETRLTSLVANVLVGLSLFLLPYPLQWIPKPVLYGLFLYIALTSIDGSQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLVILCGFGMSPLPYMKMIFPLIMIGMIPIRYNLLPKIIESKYLDAMD 864
BLAST of slc4a-4 vs. Ensembl Xenopus
Match: SLC4A11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:100486382]) HSP 1 Score: 504.212 bits (1297), Expect = 7.905e-163 Identity = 331/807 (41.02%), Postives = 485/807 (60.10%), Query Frame = 2
Query: 644 TADENGEGLPCLVLARLEK-IPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIY--PLAMDVSIG---QMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLF---------AQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVT---------TLVNKTVPIVNTTLAKGLLNSTNEFITITTEESR--------KENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFK-TRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSP-LHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
TA+ G C++L K + +K+F EVRA D++ FL + +ILD A +D ++ +L+ P + S M T T++ H L+ T++G+ G+ QSW+ +C++ + KRHV I+RL+ P N G +S V FV+LV+ P K K TK+ E+ RTF+T+ SD+ FR +LL A L N L + ++ + +++ E N +G GI DD+ +R+PVY D+ DGI G I K ++ FLYFACLLPS+AFG L D++T G I+V++ I+ Q +GG+ ++L GQPL+V+LTTAPL LYI VI I Y+L F ++W G++NS FLILYSL + S LM+ RSTEEI ALFISI F++DA+K ++K+F K Y+ NK +P +N T + LLNST S +E+ +L L+L+ GT+WLG F K+P+L+S R +++D +LP++VL S +GSY FK+I I F ++E F + + + + + +A+GL F LS+LFF++QN+ +++ N P N+L KG+AYHWDLL+VA+IN LS+FG+PW+H HS A + +GH IYETIV VRETRLT L++++L+GLSL LLP PL ++P VL GLF+Y+A+T++ G+QL ERV LL EQ AYPP+HY+RRVPQRK+H FT LQ+ QL +LC G +P PY K+ FP++++ +PIR+ + PK I Y+DA+D
Sbjct: 79 TAENESSG--CVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAKASIILDETATSLDDVLREMLKHFVEDPENAEPSCNFNKIMSTLFTDSGAPREGNVHL-------LSDTIQGVTATAT-GVQYQQSWLCIICTIKSLQKRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFSTMFSDINFRQKLLETKTEEEFKEALVHQRHLLTLVNKHSSLNDGHKVQSHKPLKLNEFFN----------VGKGIFDDIARRLPVYPLDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDESTAGVIDVQKTIVGQCIGGVIYSLFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFKAFYAWTGLWNSCFLILYSLFNCSLLMKLFKRSTEEIIALFISITFVLDALKGIIKIFKKYYLEIPSSHTYPDQEYNKHLPNLNFT-SDVLLNSTFNGSVFAPNGSSDHEEIHYGRESAVLSLMLMFGTLWLGHTLYQFKKSPYLHSRVREMLSDCALPISVLTFSVVGSYFFKEIHIAKFNYIKTESMFVLAPIG--SLPMGPITSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSVFGMPWIHAAFLHSHNARAGARQSWKREWSTGH-IYETIVSVRETRLTSLVANVLVGLSLFLLPYPLQWIPKPVLYGLFLYIALTSIDGSQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLVILCGFGMSPLPYMKMIFPLIMIGMIPIRYNLLPKIIESKYLDAMD 861
BLAST of slc4a-4 vs. Ensembl Xenopus
Match: SLC4A11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:100486382]) HSP 1 Score: 486.878 bits (1252), Expect = 3.473e-156 Identity = 318/769 (41.35%), Postives = 466/769 (60.60%), Query Frame = 2
Query: 707 IKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIY--PLAMDVSIG---QMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLF---------AQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTL---------VNKTVPIVNTTLAKGLLNSTNEFITITTEESR--------KENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFK-TRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSP-LHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRH 2911
+K+F EVRA D++ FL + +ILD A +D ++ +L+ P + S M T T++ H L+ T++G+ G+ QSW+ +C++ + KRHV I+RL+ P N G +S V FV+LV+ P K K TK+ E+ RTF+T+ SD+ FR +LL A L N L + ++ + +++ + E F +G GI DD+ +R+PVY D+ DGI G I K ++ FLYFACLLPS+AFG L D++T G I+V++ I+ Q +GG+ ++L GQPL+V+LTTAPL LYI VI I Y+L F ++W G++NS FLILYSL + S LM+ RSTEEI ALFISI F++DA+K ++K+F K Y+ NK +P +N T + LLNST S +E+ +L L+L+ GT+WLG F K+P+L+S R +++D +LP++VL S +GSY FK+I I F ++E F + + + + + +A+GL F LS+LFF++QN+ +++ N P N+L KG+AYHWDLL+VA+IN LS+FG+PW+H HS A + +GH IYETIV VRETRLT L++++L+GLSL LLP PL ++P VL GLF+Y+A+T++ G+QL ERV LL EQ AYPP+HY+RRVPQRK+H FT LQ+ QL +LC G +P PY K+ FP++++ +PIR+
Sbjct: 93 LKNFEEEVRAHRDLDGFLAKASIILDETATSLDDVLREMLKHFVEDPENAEPSCNFNKIMSTLFTDSGAPREGNVHL-------LSDTIQGVTATAT-GVQYQQSWLCIICTIKSLQKRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFSTMFSDINFRQKLLETKTEEEFKEALVHQRHLLTLVNKHSSLNDGHKVQSHKPLKVRG--SSPPKLNEFFNVGKGIFDDIARRLPVYPLDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDESTAGVIDVQKTIVGQCIGGVIYSLFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFKAFYAWTGLWNSCFLILYSLFNCSLLMKLFKRSTEEIIALFISITFVLDALKGIIKIFKKYYLEIPSSHTYPDQEYNKHLPNLNFT-SDVLLNSTFNGSVFAPNGSSDHEEIHYGRESAVLSLMLMFGTLWLGHTLYQFKKSPYLHSRVREMLSDCALPISVLTFSVVGSYFFKEIHIAKFNYIKTESMFVLAPIG--SLPMGPITSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSVFGMPWIHAAFLHSHNARAGARQSWKREWSTGH-IYETIVSVRETRLTSLVANVLVGLSLFLLPYPLQWIPKPVLYGLFLYIALTSIDGSQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLVILCGFGMSPLPYMKMIFPLIMIGMIPIRY 847
BLAST of slc4a-4 vs. Ensembl Xenopus
Match: SLC4A11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:100486382]) HSP 1 Score: 472.626 bits (1215), Expect = 3.465e-152 Identity = 307/751 (40.88%), Postives = 453/751 (60.32%), Query Frame = 2
Query: 707 IKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIY--PLAMDVSIG---QMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLF---------AQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSP-LHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRH 2911
+K+F EVRA D++ FL + +ILD A +D ++ +L+ P + S M T T++ H L+ T++G+ G+ QSW+ +C++ + KRHV I+RL+ P N G +S V FV+LV+ P K K TK+ E+ RTF+T+ SD+ FR +LL A L N L + ++ + +++ E N +G GI DD+ +R+PVY D+ DGI G I K ++ FLYFACLLPS+AFG L D++T G I+V++ I+ Q +GG+ ++L GQPL+V+LTTAPL LYI VI I Y+L F ++W G++NS FLILYSL + S LM+ RSTEEI ALFISI F++DA+K ++K KS N + +V E + T +E+ +L L+L+ GT+WLG F K+P+L+S R +++D +LP++VL S +GSY FK+I ++ + F + + + + + +A+GL F LS+LFF++QN+ +++ N P N+L KG+AYHWDLL+VA+IN LS+FG+PW+H HS A + +GH IYETIV VRETRLT L++++L+GLSL LLP PL ++P VL GLF+Y+A+T++ G+QL ERV LL EQ AYPP+HY+RRVPQRK+H FT LQ+ QL +LC G +P PY K+ FP++++ +PIR+
Sbjct: 21 LKNFEEEVRAHRDLDGFLAKASIILDETATSLDDVLREMLKHFVEDPENAEPSCNFNKIMSTLFTDSGAPREGNVHL-------LSDTIQGVTATAT-GVQYQQSWLCIICTIKSLQKRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFSTMFSDINFRQKLLETKTEEEFKEALVHQRHLLTLVNKHSSLNDGHKVQSHKPLKLNEFFN----------VGKGIFDDIARRLPVYPLDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDESTAGVIDVQKTIVGQCIGGVIYSLFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFKAFYAWTGLWNSCFLILYSLFNCSLLMKLFKRSTEEIIALFISITFVLDALKGIIKS--KSIYYPQTNSNMRLV-----------WKELLGYTEIHYGRESAVLSLMLMFGTLWLGHTLYQFKKSPYLHSRVREMLSDCALPISVLTFSVVGSYFFKEI-----HSKLPDMFVLAPIG--SLPMGPITSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSVFGMPWIHAAFLHSHNARAGARQSWKREWSTGH-IYETIVSVRETRLTSLVANVLVGLSLFLLPYPLQWIPKPVLYGLFLYIALTSIDGSQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLVILCGFGMSPLPYMKMIFPLIMIGMIPIRY 732
BLAST of slc4a-4 vs. Ensembl Xenopus
Match: SLC4A11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:100486382]) HSP 1 Score: 454.136 bits (1167), Expect = 1.273e-144 Identity = 309/766 (40.34%), Postives = 456/766 (59.53%), Query Frame = 2
Query: 644 TADENGEGLPCLVLARLEK-IPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIY--PLAMDVSIG---QMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEML--QNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSP-LHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRH 2911
TA+ G C++L K + +K+F EVRA D++ FL + +ILD A +D ++ +L+ P + S M T T++ H L+ T++G+ G+ QSW+ +C++ + KRHV I+RL+ P N G +S V FV+LV+ P K K TK+ E+ RTF+T+ SD+ FR +LL +TE+EFKE L Q H L + +N E F +G GI DD+ +R+PVY D+ DGI G I K ++ FLYFACLLPS+AFG L D++T G I+V++ I+ Q +GG+ ++L GQPL+V+LTTAPL LYI VI I Y+L F ++W G++NS FLILYSL + S LM+ RSTEEI ALFISI F++DA+K ++K +K++ + + G + + + +G G +WL P+L+S R +++D +LP++VL S +GSY FK+I ++ + F + + + + + +A+GL F LS+LFF++QN+ +++ N P N+L KG+AYHWDLL+VA+IN LS+FG+PW+H HS A + +GH IYETIV VRETRLT L++++L+GLSL LLP PL ++P VL GLF+Y+A+T++ G+QL ERV LL EQ AYPP+HY+RRVPQRK+H FT LQ+ QL +LC G +P PY K+ FP++++ +PIR+
Sbjct: 64 TAENESSG--CVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAKASIILDETATSLDDVLREMLKHFVEDPENAEPSCNFNKIMSTLFTDSGAPREGNVHL-------LSDTIQGVTATAT-GVQYQQSWLCIICTIKSLQKRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFSTMFSDINFRQKLLETKTEEEFKEALVHQRHLLTLVNKH-----------SSLNDGHKLNEFFNVGKGIFDDIARRLPVYPLDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDESTAGVIDVQKTIVGQCIGGVIYSLFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFKAFYAWTGLWNSCFLILYSLFNCSLLMKLFKRSTEEIIALFISITFVLDALKGIIK-----------SKSIYCIISVRPLGRDWGCGIAGIVGRDGAYSSSGW-------GGLWL----------PYLHSRVREMLSDCALPISVLTFSVVGSYFFKEI-----HSKLPDMFVLAPIG--SLPMGPITSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSVFGMPWIHAAFLHSHNARAGARQSWKREWSTGH-IYETIVSVRETRLTSLVANVLVGLSLFLLPYPLQWIPKPVLYGLFLYIALTSIDGSQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLVILCGFGMSPLPYMKMIFPLIMIGMIPIRY 772
BLAST of slc4a-4 vs. Ensembl Mouse
Match: Slc4a11 (solute carrier family 4, sodium bicarbonate transporter-like, member 11 [Source:MGI Symbol;Acc:MGI:2138987]) HSP 1 Score: 530.406 bits (1365), Expect = 5.372e-173 Identity = 345/792 (43.56%), Postives = 497/792 (62.75%), Query Frame = 2
Query: 674 CLVLARLEK-IPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDT--------FITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEML--QNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYV-----TTLVNKTVPI----------VNTTLAKGLLNSTNEFITITTE---ESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
C++L K + +K+F EVRA D++ FL + +IL+ A +D ++ +L A+D + + D T+A + K H + + Q + T++G+ +QSW+ +C++ + KRHV I+RL P N G +S V FV+LV+ P K K TK+ +E++RTFAT+ SD+ FR +LL +TE+EFKE L Q + + S T Q ++ FP G GI D+ +R PVY D+ DGI G ++ K V+ FLYFACLLP++AFG L D+NT+G I+V++ I Q++GGL +AL GQPL+++LTTAPL +Y +VI I Y+L F ++W G++NS FL LY+ L+LS LM RSTEEI ALFISI F++DAVK ++K+F K Y T + V + ++T L LL S E T ++ S + +L LL+++GT+WLG F K+P+L+ R ++D +LP+AVL S IGSY F++I++ F+ E + +S A+ +A+GL F LSLLFF++QN+ +A+VN P N+L KG+AYHWDLL++AIIN LSLFGLPW+H PHSPLHV+ALA +EER+++GH IYETIV V+ETRLT L + +L+GLSLLLLP PL ++P VL GLF+Y+A+T+L GNQL RV LL EQ +YPP+HY+RRVPQRK+H FT LQ+ QL LLCA G + PY K+ FP++++ +PIR+ + P+ I Y+D +D
Sbjct: 79 CVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAQASIILNETATSLDDVLRTMLNR---FALDPNHAEPDCDLDLLMAKLFTDAGAPMESKVHLLSDTIQGVTATVRGV--------QYEQSWLCIICTMKTLQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDITFRQKLLKTRTEEEFKEALVHQRQLLTMMMPRAAGHSMSSLHTHRHPQPPKCKDFFPFGKGIWMDIMRRFPVYPMDFTDGIIGKSKSVGKYVTTTLFLYFACLLPTIAFGSLNDENTNGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLAIYTQVIRVICDDYNLDFNAFYAWTGLWNSFFLALYAFLNLSLLMNLFKRSTEEIIALFISITFVLDAVKGMVKIFGKYYYGHHYHTKRTSSLVSLLGIGRSPNSSLHTALNASLLASPVEMATTSSPGSTHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVRETLSDCALPIAVLSFSLIGSYGFQEIEMSKFRYNPSESL-FEVAQIHSLSFKAIGSAMGLGFLLSLLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGH-IYETIVDVKETRLTALGASVLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSLDGNQLFSRVALLLKEQTSYPPTHYIRRVPQRKIHYFTGLQILQLLLLCAFGMSSLPYMKMVFPLIMIAMIPIRYNLLPRIIEAKYLDVMD 857
BLAST of slc4a-4 vs. Ensembl Mouse
Match: Slc4a1 (solute carrier family 4 (anion exchanger), member 1 [Source:MGI Symbol;Acc:MGI:109393]) HSP 1 Score: 189.504 bits (480), Expect = 8.768e-49 Identity = 160/536 (29.85%), Postives = 284/536 (52.99%), Query Frame = 2
Query: 1376 NGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIM----SFI-GSYLFKDIKIDTFK--TRSEEEFSIKFVNFSQI-SISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
G++ D+R+R P Y+SD D + ++++A F+YFA L P++ FG L + T + V +++S V G+ FAL+G QPL+V+ + PL ++ + ++ +L + +W+G + + ++L + S L+++ +R T+EIF+ IS+ FI + ++K+F + Y L P+V +G + +T F + L+ GT L + F + + R ++ D+ +P+++LIM SFI G+Y K D K S + I + ++ +FA++ A + +L F++ +T+ +V+ P K+ KGS +H DLL+V + V +LFG+PW+ T S H AL + + SG I +V+E R++GL+ +L+GLS+L+ PI +P+AVL G+F+YM +T+L G QL +R++LLF +P +++RV ++HLFT +Q+ L +L + P A + P +L+L +P+R I P + LD
Sbjct: 399 GGLIRDIRRRYPYYLSDITDALS-----PQVLAAVIFIYFAALSPAVTFGGLLGEKTRNLMGVSELLISTAVQGILFALLGAQPLLVLGFSGPLLVFEEAFFSFCESNNLEYIVGRAWIGFWLILLVMLVVAFEGSFLVQYISRYTQEIFSFLISLIFIYETFSKLIKIF-QDY--PLQQTYAPVVMKPKPQGPVPNTALFSLV---------------LMAGTFLLAMTLRKFKNSTYFPGKLRRVIGDFGVPISILIMVLVDSFIKGTYTQKLSVPDGLKVSNSSARGWVIHPLGLYRLFPTWMMFASVLPALLVFILIFLESQITTLIVSKPERKMIKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKA--SGPGAAAQIQEVKEQRISGLLVSVLVGLSILMEPILSR-IPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPFVKRVKTWRMHLFTGIQIICLAVLWVVKSTP---ASLALPFVLILTVPLRRLILPLIFRELELQCLD 905
BLAST of slc4a-4 vs. Ensembl Mouse
Match: Slc4a2 (solute carrier family 4 (anion exchanger), member 2 [Source:MGI Symbol;Acc:MGI:109351]) HSP 1 Score: 174.481 bits (441), Expect = 1.161e-43 Identity = 153/562 (27.22%), Postives = 269/562 (47.86%), Query Frame = 2
Query: 1367 PLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKT------VPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXI----GTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISA------VFAALGLAFPLS---------------LLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
P G G++ D+R+R P Y+SD++D + + ++A F+YFA L P++ FG L + T I V +I+S + G+ F L+G QPL+V+ + PL ++ + ++ + L + W+G + +L L+ S L+R+ +R T+EIFA IS+ FI + ++K+F + + N T A +L N + + + + LL + GT ++ + F + F R ++ D+ +P+A+LIM + D I E+ ++ K S S++A V LG P +L FM+ +T+ +++ L+KGS +H DLL++ + + +LFGLPW+ S H AL + + + G + I +V+E R + L+ +++ L +P+AVL G+F+YM +T+L G Q ER+ LL +P Y+++V ++HLFT LQL L LL A+ A + FP +L+L +P+R + + + + LD
Sbjct: 668 PFG-GLIRDVRRRYPHYLSDFRDALDP-----QCLAAVIFIYFAALSPAITFGGLLGEKTKDLIGVSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNELEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLIKIFQEHPLHGCSGSNDSEAGSSSSSNMTWATTILVPDNSSASGQSGQEKPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLV------DYSI-------EDTYTQKLSVPSGFSVTAPDKRGWVINPLGEKTPFPVWMMVASLLPAVLVFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDK--PKIQEVKEQR-VTGLLVALLVGLSMVIGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTMRMHLFTALQLLCLALLWAVMST---AASLAFPFILILTVPLRMVVLTRIFTEREMKCLD 1204
BLAST of slc4a-4 vs. Ensembl Mouse
Match: Slc4a2 (solute carrier family 4 (anion exchanger), member 2 [Source:MGI Symbol;Acc:MGI:109351]) HSP 1 Score: 174.096 bits (440), Expect = 1.163e-43 Identity = 153/562 (27.22%), Postives = 269/562 (47.86%), Query Frame = 2
Query: 1367 PLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKT------VPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXI----GTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISA------VFAALGLAFPLS---------------LLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
P G G++ D+R+R P Y+SD++D + + ++A F+YFA L P++ FG L + T I V +I+S + G+ F L+G QPL+V+ + PL ++ + ++ + L + W+G + +L L+ S L+R+ +R T+EIFA IS+ FI + ++K+F + + N T A +L N + + + + LL + GT ++ + F + F R ++ D+ +P+A+LIM + D I E+ ++ K S S++A V LG P +L FM+ +T+ +++ L+KGS +H DLL++ + + +LFGLPW+ S H AL + + + G + I +V+E R + L+ +++ L +P+AVL G+F+YM +T+L G Q ER+ LL +P Y+++V ++HLFT LQL L LL A+ A + FP +L+L +P+R + + + + LD
Sbjct: 663 PFG-GLIRDVRRRYPHYLSDFRDALDP-----QCLAAVIFIYFAALSPAITFGGLLGEKTKDLIGVSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNELEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLIKIFQEHPLHGCSGSNDSEAGSSSSSNMTWATTILVPDNSSASGQSGQEKPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLV------DYSI-------EDTYTQKLSVPSGFSVTAPDKRGWVINPLGEKTPFPVWMMVASLLPAVLVFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDK--PKIQEVKEQR-VTGLLVALLVGLSMVIGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTMRMHLFTALQLLCLALLWAVMST---AASLAFPFILILTVPLRMVVLTRIFTEREMKCLD 1199
BLAST of slc4a-4 vs. Ensembl Mouse
Match: Slc4a2 (solute carrier family 4 (anion exchanger), member 2 [Source:MGI Symbol;Acc:MGI:109351]) HSP 1 Score: 173.711 bits (439), Expect = 1.905e-43 Identity = 153/562 (27.22%), Postives = 269/562 (47.86%), Query Frame = 2
Query: 1367 PLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKT------VPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXI----GTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISA------VFAALGLAFPLS---------------LLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
P G G++ D+R+R P Y+SD++D + + ++A F+YFA L P++ FG L + T I V +I+S + G+ F L+G QPL+V+ + PL ++ + ++ + L + W+G + +L L+ S L+R+ +R T+EIFA IS+ FI + ++K+F + + N T A +L N + + + + LL + GT ++ + F + F R ++ D+ +P+A+LIM + D I E+ ++ K S S++A V LG P +L FM+ +T+ +++ L+KGS +H DLL++ + + +LFGLPW+ S H AL + + + G + I +V+E R + L+ +++ L +P+AVL G+F+YM +T+L G Q ER+ LL +P Y+++V ++HLFT LQL L LL A+ A + FP +L+L +P+R + + + + LD
Sbjct: 677 PFG-GLIRDVRRRYPHYLSDFRDALDP-----QCLAAVIFIYFAALSPAITFGGLLGEKTKDLIGVSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNELEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLIKIFQEHPLHGCSGSNDSEAGSSSSSNMTWATTILVPDNSSASGQSGQEKPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLV------DYSI-------EDTYTQKLSVPSGFSVTAPDKRGWVINPLGEKTPFPVWMMVASLLPAVLVFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDK--PKIQEVKEQR-VTGLLVALLVGLSMVIGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTMRMHLFTALQLLCLALLWAVMST---AASLAFPFILILTVPLRMVVLTRIFTEREMKCLD 1213
BLAST of slc4a-4 vs. UniProt/SwissProt
Match: sp|Q8NBS3|S4A11_HUMAN (Sodium bicarbonate transporter-like protein 11 OS=Homo sapiens OX=9606 GN=SLC4A11 PE=1 SV=2) HSP 1 Score: 553.132 bits (1424), Expect = 1.533e-180 Identity = 345/806 (42.80%), Postives = 506/806 (62.78%), Query Frame = 2
Query: 644 TADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQ--------MDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAE-------EQRLYRRRSIRITEVMNQAFAYEEKF-PLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVN-----KTVPIVNTTLAKGLLNST------NEFITITTE-----ESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFK-TRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
T +E G L+ + + +K+F E+RA D++ FL + ++L+ A +D ++ +LR A D + M T+A + K H L+ T++G+ G+ QSW+ +C++ + KRHV I+RL P N G +S V FV+LV+ P K K TK+ +E++RTFAT+ SD+ FR +LL +TE+EFKE L H R L R R ++ + + + F P G GI +D+ +R P+Y D+ DGI G + K ++ FLYFACLLP++AFG L D+NTDG I+V++ I Q++GGL +AL GQPL+++LTTAPL LYI+VI I Y L F + ++W G++NS FL LY+ +LS +M RSTEEI ALFISI F++DAVK +K+F+K Y ++ +T +V+ + LN++ F+ TE S + +L LL+++GT+WLG F K+P+L+ R +++D +LP+AVL S I S+ F++I++ F+ SE F++ +S+ AV A+GL F LS+LFF++QN+ +A+VN P N+L KG+AYHWDLL++AIIN LSLFGLPW+H PHSPLHV+ALA +EER+++GH IY+TIV V+ETRLT L + +L+GLSLLLLP+PL ++P VL GLF+Y+A+T+L GNQLV+RV LL EQ AYPP+HY+RRVPQRK+H FT LQ+ QL LLCA G + PY K+ FP++++ +PIR+ + P+ I Y+D +D
Sbjct: 96 TENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRR---FARDPDNNEPNCNLDLLMAMLFTDAGAPMRGKVHL-------LSDTIQGVTATVT-GVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALV-HQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAM--AQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGH-IYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMD 886
BLAST of slc4a-4 vs. UniProt/SwissProt
Match: sp|A2AJN7|S4A11_MOUSE (Sodium bicarbonate transporter-like protein 11 OS=Mus musculus OX=10090 GN=Slc4a11 PE=2 SV=1) HSP 1 Score: 530.406 bits (1365), Expect = 3.758e-172 Identity = 345/792 (43.56%), Postives = 497/792 (62.75%), Query Frame = 2
Query: 674 CLVLARLEK-IPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDT--------FITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEML--QNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYV-----TTLVNKTVPI----------VNTTLAKGLLNSTNEFITITTE---ESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
C++L K + +K+F EVRA D++ FL + +IL+ A +D ++ +L A+D + + D T+A + K H + + Q + T++G+ +QSW+ +C++ + KRHV I+RL P N G +S V FV+LV+ P K K TK+ +E++RTFAT+ SD+ FR +LL +TE+EFKE L Q + + S T Q ++ FP G GI D+ +R PVY D+ DGI G ++ K V+ FLYFACLLP++AFG L D+NT+G I+V++ I Q++GGL +AL GQPL+++LTTAPL +Y +VI I Y+L F ++W G++NS FL LY+ L+LS LM RSTEEI ALFISI F++DAVK ++K+F K Y T + V + ++T L LL S E T ++ S + +L LL+++GT+WLG F K+P+L+ R ++D +LP+AVL S IGSY F++I++ F+ E + +S A+ +A+GL F LSLLFF++QN+ +A+VN P N+L KG+AYHWDLL++AIIN LSLFGLPW+H PHSPLHV+ALA +EER+++GH IYETIV V+ETRLT L + +L+GLSLLLLP PL ++P VL GLF+Y+A+T+L GNQL RV LL EQ +YPP+HY+RRVPQRK+H FT LQ+ QL LLCA G + PY K+ FP++++ +PIR+ + P+ I Y+D +D
Sbjct: 79 CVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAQASIILNETATSLDDVLRTMLNR---FALDPNHAEPDCDLDLLMAKLFTDAGAPMESKVHLLSDTIQGVTATVRGV--------QYEQSWLCIICTMKTLQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDITFRQKLLKTRTEEEFKEALVHQRQLLTMMMPRAAGHSMSSLHTHRHPQPPKCKDFFPFGKGIWMDIMRRFPVYPMDFTDGIIGKSKSVGKYVTTTLFLYFACLLPTIAFGSLNDENTNGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLAIYTQVIRVICDDYNLDFNAFYAWTGLWNSFFLALYAFLNLSLLMNLFKRSTEEIIALFISITFVLDAVKGMVKIFGKYYYGHHYHTKRTSSLVSLLGIGRSPNSSLHTALNASLLASPVEMATTSSPGSTHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVRETLSDCALPIAVLSFSLIGSYGFQEIEMSKFRYNPSESL-FEVAQIHSLSFKAIGSAMGLGFLLSLLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGH-IYETIVDVKETRLTALGASVLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSLDGNQLFSRVALLLKEQTSYPPTHYIRRVPQRKIHYFTGLQILQLLLLCAFGMSSLPYMKMVFPLIMIAMIPIRYNLLPRIIEAKYLDVMD 857
BLAST of slc4a-4 vs. UniProt/SwissProt
Match: sp|P15575|B3AT_CHICK (Band 3 anion transport protein OS=Gallus gallus OX=9031 GN=SLC4A1 PE=2 SV=1) HSP 1 Score: 199.519 bits (506), Expect = 3.945e-51 Identity = 172/669 (25.71%), Postives = 313/669 (46.79%), Query Frame = 2
Query: 1106 VYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQN--------HARDLAEEQRLY----------RRR-----SIR-------ITEVMNQAFAYEEKFPL------GNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVF-----YKSYVTTL-VNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEE---------FSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
V FV+ V+ P + + +I R AT+++D FR E LQ +++ EQ L+ RRR ++R + ++ A ++ PL G+V D+R+R P Y+SD +D + + ++A F+YFA L P++ FG L + T G + V ++LS +V L F+L+ QPL+V+ + PL ++ + + + L + W+G + + ++L + + L+R+ +R T+EIF+ IS+ FI + ++ +F +SY T + +VP NT L +L + GT +L ++ F + FL R L+ D+ +P+++ +M+ + + KD K E F + + I +FA+ A + +L F++ +T+ +V+ P KL KGS +H DLL++ + + +LFG+PW+ T + H AL + + G R + IV+V+E R + ++ +L+ L Y+P+AVL G+F+YM +T+L+G QL +R++LL +P Y+ RV ++ + Q+ + LL + +P A + P +L+L +P+R + P+ S + LD
Sbjct: 269 VRFVLTVLGPDSPRLSYHEIR--RAAATVMADRVFRRDAYLCGGRAELLGGLQGFLEASIVLPPQEVPSEQHLHALIPLQRHAVRRRYQHPDTVRSPGGPTAPKDTGDKGQAPQDDDPLLRTRRPFGGLVRDIRRRYPKYLSDIRDALN-----PQCLAAVIFIYFAALSPAITFGGLLGEKTRGMMGVSELLLSTSVQCLLFSLLSAQPLLVVGFSGPLLVFEEAFFRFCEDHGLEYIVGRVWIGFWLILLVLLVVACEGTVLVRYLSRYTQEIFSFLISLIFIYETFAKLVTIFEAHPLQQSYDTDVSTEPSVPKPNTALLSLVLMA-------------------------GTFFLALFLRQFKNSVFLPGKVRRLIGDFGVPISIFVMA-LADFFIKDTYTQKLKVPRGLEVTNGTARGWFIHPMGSATPFPIWMMFASPVPALLVFILIFLETQITTLIVSKPERKLVKGSGFHLDLLLIVAMGGLAALFGMPWLSATTVRTITHANALTVVGKSAVPGERAH--IVEVKEQR-LSGLLVAVLIGVSILMEPILKYIPLAVLFGIFLYMGVTSLFGIQLFDRILLLLMPPKYHPKEPYVTRVKTWRITSSPLTQILVVALLWGVKVSP---ASLRCPFVLVLTVPLRRLLLPRIFSEIELKCLD 898
BLAST of slc4a-4 vs. UniProt/SwissProt
Match: sp|P02730|B3AT_HUMAN (Band 3 anion transport protein OS=Homo sapiens OX=9606 GN=SLC4A1 PE=1 SV=3) HSP 1 Score: 193.356 bits (490), Expect = 3.020e-49 Identity = 184/639 (28.79%), Postives = 314/639 (49.14%), Query Frame = 2
Query: 1166 ELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNH--------ARDLAEEQ----------RLYRRRSIRITEVMNQAF------------AYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFI-----GSYLFKDIKIDTFK--TRSEEEFSIKFVNF-SQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFP---KFISLTYIDALD 2959
+L R ATL+S+ FR AQ+ E L+ D EQ L RRR + +F ++ L G+V D+R+R P Y+SD D ++++A F+YFA L P++ FG L + T ++ V +++S V G+ FAL+G QPL+V+ + PL ++ + ++ L + W+G + + ++L + S L+R+ +R T+EIF+ IS+ FI + ++K+F + N V +V +G L +T LL L+L+ GT + + F + + R ++ D+ +P+++LIM + +Y K D FK S + I + S+ I +FA+ A + +L F++ +T+ +V+ P K+ KGS +H DLL+V + V +LFG+PW+ T S H AL + + G I +V+E R++GL+ +L+GLS+L+ PI +P+AVL G+F+YM +T+L G QL +R++LLF +P Y++RV ++HLFT +Q+ L +L + P A + P +L+L +P+R + P + + L +DA D
Sbjct: 280 QLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLSLVPVQRELLRRRYQSSPAKPDSSFYKGLDLNGGPDDPLQQTGQLFGGLVRDIRRRYPYYLSDITDAFS-----PQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTYNYNVLMVPK--PQGPLPNT---------------ALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAA--AQIQEVKEQRISGLLVAVLVGLSILMEPILSR-IPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTP---ASLALPFVLILTVPLRRVLLPLIFRNVELQCLDADD 890
BLAST of slc4a-4 vs. UniProt/SwissProt
Match: sp|P04919|B3AT_MOUSE (Band 3 anion transport protein OS=Mus musculus OX=10090 GN=Slc4a1 PE=1 SV=1) HSP 1 Score: 189.504 bits (480), Expect = 6.133e-48 Identity = 160/536 (29.85%), Postives = 284/536 (52.99%), Query Frame = 2
Query: 1376 NGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIM----SFI-GSYLFKDIKIDTFK--TRSEEEFSIKFVNFSQI-SISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
G++ D+R+R P Y+SD D + ++++A F+YFA L P++ FG L + T + V +++S V G+ FAL+G QPL+V+ + PL ++ + ++ +L + +W+G + + ++L + S L+++ +R T+EIF+ IS+ FI + ++K+F + Y L P+V +G + +T F + L+ GT L + F + + R ++ D+ +P+++LIM SFI G+Y K D K S + I + ++ +FA++ A + +L F++ +T+ +V+ P K+ KGS +H DLL+V + V +LFG+PW+ T S H AL + + SG I +V+E R++GL+ +L+GLS+L+ PI +P+AVL G+F+YM +T+L G QL +R++LLF +P +++RV ++HLFT +Q+ L +L + P A + P +L+L +P+R I P + LD
Sbjct: 399 GGLIRDIRRRYPYYLSDITDALS-----PQVLAAVIFIYFAALSPAVTFGGLLGEKTRNLMGVSELLISTAVQGILFALLGAQPLLVLGFSGPLLVFEEAFFSFCESNNLEYIVGRAWIGFWLILLVMLVVAFEGSFLVQYISRYTQEIFSFLISLIFIYETFSKLIKIF-QDY--PLQQTYAPVVMKPKPQGPVPNTALFSLV---------------LMAGTFLLAMTLRKFKNSTYFPGKLRRVIGDFGVPISILIMVLVDSFIKGTYTQKLSVPDGLKVSNSSARGWVIHPLGLYRLFPTWMMFASVLPALLVFILIFLESQITTLIVSKPERKMIKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKA--SGPGAAAQIQEVKEQRISGLLVSVLVGLSILMEPILSR-IPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPFVKRVKTWRMHLFTGIQIICLAVLWVVKSTP---ASLALPFVLILTVPLRRLILPLIFRELELQCLD 905
BLAST of slc4a-4 vs. TrEMBL
Match: A0A0H3YEW7 (Slc4a-4 OS=Schmidtea mediterranea OX=79327 GN=slc4a-4 PE=2 SV=1) HSP 1 Score: 1687.16 bits (4368), Expect = 0.000e+0 Identity = 891/891 (100.00%), Postives = 891/891 (100.00%), Query Frame = 2
Query: 296 MNNLMPTQNSLNRRNSRSVDHLNMINSYSSNDKSVPKLVLTNCNQSPAIDRTNRRTISGLYNFKKQSTNNDDKDSKDRNLLLSPTNYINRQISETSEMSTDTVSNFSIGSLARYYRTADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 2968
MNNLMPTQNSLNRRNSRSVDHLNMINSYSSNDKSVPKLVLTNCNQSPAIDRTNRRTISGLYNFKKQSTNNDDKDSKDRNLLLSPTNYINRQISETSEMSTDTVSNFSIGSLARYYRTADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNSIFLILYSLLDLSKLMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGLLFLLLLIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRLTGLISHILIGLSLLLLPIPLIYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHLFTVLQLTQLGLLCALGFAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI
Sbjct: 1 MNNLMPTQNSLNRRNSRSVDHLNMINSYSSNDKSVPKLVLTNCNQSPAIDRTNRRTISGLYNFKKQSTNNDDKDSKDRNLLLSPTNYINRQISETSEMSTDTVSNFSIGSLARYYRTADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNSIFLILYSLLDLSKLMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGLLFLLLLIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRLTGLISHILIGLSLLLLPIPLIYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHLFTVLQLTQLGLLCALGFAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 891
BLAST of slc4a-4 vs. TrEMBL
Match: A0A0H3YK00 (Slc4a-8 OS=Schmidtea mediterranea OX=79327 GN=slc4a-8 PE=2 SV=1) HSP 1 Score: 867.07 bits (2239), Expect = 0.000e+0 Identity = 468/851 (54.99%), Postives = 638/851 (74.97%), Query Frame = 2
Query: 485 KKQSTNNDDKDSKDRNLLL---SPTNYINRQI--SETSEMSTDTVSNFSIGSLARYYRTADEN-GEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQ--MDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVN---------------KTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 2968
+++ T D++ S +L L SP ++RQ S S +S D +SN S +LA + ADE + +PCL L+RLEKIP+KDFS+EVRATLD++KFLKE VL+LDM + ++ I++ +L I LA +V+ + ++ + EAK LF+++ Y ++YQRLAKT++G+ ++E EGL TDQSW+ MCSL C+HKRHVAIARL PVN+GRSSEG+YF++LV+TP KEK TKSDIEL RTFAT+ +D+EFR QLLF+++ ++FKE+LQ H+ DL E+Q + RR+S+++ EVMNQAF +++K+ +G+GIV D +KR PVY+ D++DG +G GTIRK++SA FLYFACLLPS+AFGVL NT+GKI+V+RVI+SQ +GGLCF GQPLI++LTTAPL L++K+I +I Y L F+ M+S VG+ NS+ LILY++ D+SKLMRWSTRS+EEIFALF++I+F+VDAVKD+ K F Y + ++ + + + ++ L + ++ ++E +L+L L+ GTVWL I TKTPFLN++KR ++ D++LPLAV+IMS IG+YLFK+I++ F EE+ + ++ A+ A+ LAFPLSLL FMDQN++SAMVN P+NKLKKGS+YHWDLL+VA+IN LS+FGLP VHG LPHSPLHVKALADLEERID+ H +++TIVKVRETR+T ++SH+ IG+SL +LPIPLIY+P+AVLDGLFVYMA+T LYGNQ ER++LLFTEQ+AYPPSHYLRRVPQRK+H+FT LQ+ QL LC LGF+P+PY K+GFP+LLL M RH + P+ I Y++ALDKPI
Sbjct: 68 EQEVTIKDNRTSISSHLFLLPPSPGRRLSRQRQGSSASNVSVDNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTI--LANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQPLIILLTTAPLALFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNISISLTQTNLNSSLYSSNSCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVI-VEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDKPI 915
BLAST of slc4a-4 vs. TrEMBL
Match: A0A267H8X4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030243g1 PE=4 SV=1) HSP 1 Score: 864.759 bits (2233), Expect = 0.000e+0 Identity = 463/841 (55.05%), Postives = 621/841 (73.84%), Query Frame = 2
Query: 596 DTVSNFSIGSLARYYRTADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIY-----------------------PLAM-------------------DVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTT--LVNKT-----VPIVNTTLAKGLLNSTNEFIT-ITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 2968
D +S S GSLA YYR+ D E LPCLV++RLEKIP+KDFSSE+RA LD+E+FLKE L+LD+E +++++I++ +L+ I+ P++ D + ++ + +AK LF++A + ++SYQRLAKT+K I + ++EGL TD SW+ MCSL+ V+KRHVAIARL +PVNLGRSSEGV+F++LV+TP KEK TKSDIE+ RTFAT+L+D +FR +L+ A++EDEFK M+Q+HA+DL EEQR+YRR+S+R + M QAF+YE + L NGI D+++R+ Y SD+ DG +GP T+ K++S FLYFACLLP +AFGVL + TDGKI+V+RV+LSQ +GG+ FALIGGQPLIVMLTTAPL LY ++IY +S + L F+ +F WVG+FN++ L+LY+ +D++KLMRWSTRSTEEIFALFISIAF+V+A K V VF ++Y + N T + + TL L++S+N + R++ +LFL+L GTV+L +Y LNFTKTP+LN +KR LMAD+SLP+AVL+MSF GSYLF D+ + F+ +S ++F + + +A+ A LA PLS+LFFMDQN++SAMVNCP+NKLKKGSAYH DLL+VA+IN LS GLPW+HG LPHSPLHVKALADLEERID G + +T+V+VRETR+TG++++ L+GLSLL+ P PL Y+P+ VL+GLFV MAIT++ GNQL ER++LLFTEQAAYPPSH+LRRVPQRKVH+FT+LQL QL LCA+GF+ YAK+ FP+LL LQMPIRH + PK I Y+DALDKP+
Sbjct: 145 DNLSLISGGSLAMYYRSPDGVDETLPCLVVSRLEKIPLKDFSSEIRANLDIERFLKEATLLLDLEGDNIESIIDRMLQSIFKADIEAHGSNHHHHHHHNQHHQHPVSAAAQADQAATSTGAAAADGGDPNDAALEAKVQDAKKTLFLQASWMDYSYQRLAKTIKSISVIDSEGLITDNSWLCTMCSLSGVNKRHVAIARLSSPVNLGRSSEGVHFILLVVTPTKEKGTKSDIEIGRTFATILADADFRQRLMLAESEDEFKSMMQSHAQDLGEEQRIYRRKSLRTKDFMTQAFSYENSWLLCNGIKADIKRRLRHYPSDFVDGFRGPKTLTKVLSTVIFLYFACLLPCIAFGVLNHKQTDGKISVERVVLSQGIGGVVFALIGGQPLIVMLTTAPLALYTRIIYEVSEAHGLDFFALFGWVGVFNALLLLLYATVDMAKLMRWSTRSTEEIFALFISIAFMVEAYKSVYYVFRENYSCAKPIANATDAASIANLSDATLIAPLIDSSNASTPDLAAPSCRRDISILFLMLCAGTVFLAMYLLNFTKTPYLNRAKRELMADFSLPVAVLVMSFCGSYLFSDVGLQKFECKS--IIRLQFTIATPLPAAAILGAFVLALPLSMLFFMDQNISSAMVNCPTNKLKKGSAYHLDLLVVALINGCLSCVGLPWIHGALPHSPLHVKALADLEERIDLGQHVQQTVVRVRETRITGILANCLVGLSLLMCPSPLSYIPVPVLNGLFVCMAITSVMGNQLFERILLLFTEQAAYPPSHFLRRVPQRKVHIFTLLQLLQLAALCAVGFSGIAYAKMVFPVLLGLQMPIRHLLIPKLIDENYLDALDKPM 983
BLAST of slc4a-4 vs. TrEMBL
Match: A0A267G7Q1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031769g2 PE=4 SV=1) HSP 1 Score: 851.277 bits (2198), Expect = 0.000e+0 Identity = 465/835 (55.69%), Postives = 614/835 (73.53%), Query Frame = 2
Query: 572 SETSEMSTDTVSNFSIGSLARYYRTADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSI----------------------GQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-------------VTTLVNKTVPIVNTTL-AKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 2968
S + + D +S S GSLA +YR AD E LPCLV++RLEKIP+KDFSSE+RA +D+++FLKE L+LD+E +V+ I+E +LR I+ + ++D + +AK LF++A++ +++YQRLAKT+K I + ++EGL TD SW+ MCSL V KRHVAIARL TPVNLGRSSEGV F++LV+TP KEK TKSDIEL RTFAT+L+D EFR +LL A+TE EFKEMLQ HA +L EEQ++YRR+S+R + M+QAF YE +P+ NGI DL++R+ Y+SD+ D + TIRK+V+ FLYFACL+P +AFGVL + T+G I V RVILSQ +GG+ FAL GGQPLI+MLTTAPL LY ++I+ +S + L F+ F WVG+FN+ L+LY++LDLSKLMRWSTRSTEEIFA+FIS+AF V AVK V F Y +T+ +K P N TL ++ LN ++ + + +++ +LFLLL IGTV+L +Y LNFTKTP+LN +KR LMAD+SLP++VL MSF+G+YLF++++++ F ++FV + A+ A GLA PLS+LFFM+QN++SAMVNCP+NKL+KGSAYH DLL VA++N V+S FGLPWVHG LPHSPLHVKALADLEERID G +++++V+VRETR+TG++S++LIGLSLL+ P+PL ++P+ VLDGLFV MAITAL+ NQL ER++LLFTEQAAYPPSHYLRRVPQRKVH+FT LQL QL +LCALGF YAK+GFP++L LQMP+RH + PK I Y+DALDKP+
Sbjct: 98 SSAASVDRDNLSIMSGGSLAMFYRNADGTDESLPCLVVSRLEKIPLKDFSSEIRANMDIQRFLKEATLLLDVEGANVECIIEQMLRSIFRADHESHHSSGSGGGGGDGGSVAGAAGAIDSRLDAKVQDAKKTLFLQANWMDYTYQRLAKTIKSISVVDSEGLITDNSWLCTMCSLNGVQKRHVAIARLSTPVNLGRSSEGVSFILLVVTPTKEKGTKSDIELGRTFATILADSEFRQKLLLAETESEFKEMLQGHAHELGEEQKIYRRKSLRTKDFMSQAFNYESSWPICNGIRADLKRRLSHYLSDFIDAFRDNKTIRKVVTTVIFLYFACLMPCIAFGVLNNSLTNGYITVHRVILSQCIGGVTFALFGGQPLIIMLTTAPLALYTRIIFELSQNHGLDFFAFFGWVGVFNAALLLLYAVLDLSKLMRWSTRSTEEIFAMFISVAFTVGAVKSVYGNFDTYYCDGNGGAETNGGNLTSGSDKWGP--NLTLDSQSALNGSSS-VGQKQQNCQRDVSILFLLLCIGTVFLSMYLLNFTKTPYLNRAKRELMADFSLPVSVLAMSFVGTYLFRNVQLEKFSCL--PYIQLEFVIARPLPGLAILGAFGLAIPLSMLFFMEQNISSAMVNCPANKLRKGSAYHLDLLTVALMNGVMSCFGLPWVHGALPHSPLHVKALADLEERIDLGQHVHQSVVRVRETRITGVVSNVLIGLSLLMCPVPLSFIPVPVLDGLFVCMAITALFDNQLFERILLLFTEQAAYPPSHYLRRVPQRKVHIFTCLQLLQLFVLCALGFNSIAYAKLGFPVILFLQMPVRHLLIPKLIDENYLDALDKPM 927
BLAST of slc4a-4 vs. TrEMBL
Match: A0A267H2A6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031769g1 PE=4 SV=1) HSP 1 Score: 848.966 bits (2192), Expect = 0.000e+0 Identity = 465/834 (55.76%), Postives = 607/834 (72.78%), Query Frame = 2
Query: 572 SETSEMSTDTVSNFSIGSLARYYRTADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSI----------------------GQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKG--------LLNSTNEFITITTEESRKEN-----GXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 2968
S + + D +S S GSLA +YR AD E LPCLV++RLEKIP+KDFSSE+RA +D+++FLKE L+LD+E +V+ I+E +LR I+ + ++D + +AK LF++A++ +++YQRLAKT+K I + ++EGL TD SW+ MCSL V KRHVAIARL TPVNLGRSSEGV F++LV+TP KEK TKSDIEL RTFAT+L+D EFR +LL A+TE EFKEMLQ HA +L EEQ++YRR+S+R + M+QAF+YE +P+ NGI DL++R+ Y+SD+ D + TIRK+V+ FLYFACL+P +AFGVL + T+G I V RVILSQ +GG+ FAL GGQPLIVMLTTAPL LY +I+ +S + L F+ F WVG+FN+ L+LY++LDLSKLMRWSTRSTEEIFA+FIS+AF V AVK V F Y N L G L+S + ++ +++N +LFLLL IGTV+L +Y LNFTKTP+LN +KR LMAD+SLP++VL MSF+G+YLF++++++ F ++FV + A+ A GLA PLS+LFFM+QN++SAMVNCP+NKL+KGSAYH DLL VA++N V+S FGLPWVHG LPHSPLHVKALADLEERID G +++++V+VRETR+TG++S+ILIGLSLL+ P+PL ++P+ VLDGLFV MAITAL+ NQL ER++LLFTEQAAYPPSHYLRRVPQRKVH+FT LQL QL +LCALGF YAK+GFP++L LQMP+RH + PK I Y+DALDKP+
Sbjct: 98 SSAASVDRDNLSIMSGGSLAMFYRNADGTDESLPCLVVSRLEKIPLKDFSSEIRANMDIQRFLKEATLLLDVEGANVECIIEQMLRSIFRADHESHHSSGSGGGGGDGGSVAGAAGAIDSRLDAKVQDAKKTLFLQANWMDYTYQRLAKTIKSISVVDSEGLITDNSWLCTMCSLNGVQKRHVAIARLSTPVNLGRSSEGVSFILLVVTPTKEKGTKSDIELGRTFATILADSEFRQKLLLAETESEFKEMLQGHAHELGEEQKIYRRKSLRTKDFMSQAFSYESSWPICNGIRADLKRRLSHYLSDFIDAFRDNKTIRKVVTTVIFLYFACLMPCIAFGVLNNSLTNGYITVHRVILSQCIGGVTFALFGGQPLIVMLTTAPLALYTHIIFELSQNHGLDFFAFFGWVGVFNAALLLLYAVLDLSKLMRWSTRSTEEIFAMFISVAFTVGAVKSVYGNFDTYYCDG--NGGAETNGGNLTSGSDKWGRNLTLDSQSALNGSSSVGQKQQNCQRDVSILFLLLCIGTVFLSMYLLNFTKTPYLNRAKRELMADFSLPVSVLAMSFVGTYLFRNVQLENFSCL--PYIQLEFVIARPLPGLAILGAFGLAIPLSMLFFMEQNISSAMVNCPANKLRKGSAYHLDLLTVALMNGVMSCFGLPWVHGALPHSPLHVKALADLEERIDLGQHVHQSVVRVRETRITGVVSNILIGLSLLMCPVPLSFIPVPVLDGLFVCMAITALFDNQLFERILLLFTEQAAYPPSHYLRRVPQRKVHIFTCLQLLQLFVLCALGFNSIAYAKLGFPVILFLQMPVRHLLIPKLIDENYLDALDKPM 927
BLAST of slc4a-4 vs. Ensembl Cavefish
Match: ENSAMXT00000011908.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000151.1:229098:263825:-1 gene:ENSAMXG00000011585.2 transcript:ENSAMXT00000011908.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 497.278 bits (1279), Expect = 2.703e-161 Identity = 314/764 (41.10%), Postives = 487/764 (63.74%), Query Frame = 2
Query: 707 IKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIR--ITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-VTTLVNKTVPIVN---------TTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
+ +F EVRA D+ FL + ++LD A +D ++ +L+ + A D GQ E +ALF A + S L +T++ + G+ QSW+ +C++ + +R V I RL+ P N G + V FV+L++ P + K TK+ IEL RTFATL SD+ FR +LL +T+D+FK+ L + + L+ + + SI +N+ +E G GI +DL +R+P Y+SD+ DG+ G ++ K + A FLY A LLP++AFG L D++T G+I+V++ I+ Q++GG+ ++L+ G P+++ +TTAPL ++I VI I Y L F ++ +G++NS+FLIL L ++S M+ RSTEE+ ALFISIAF+ DAVK +K+F+K Y TLVN + ++ + + S + +T+ T +E +L LLL++GT+WLG ++PFL++ R +++D +LP++V+I SF+GSYLF DI++ F + F+I ++ +S V +A GL F L+LL F+DQN+ ++ N P N+L KG+AYHWDL++ IN+++S+ GLPW+H PHS LHV+ LA +E+R++ GH +YETIV V+ETRLT L +++LIGLS+ LLP+PL ++P VL GLF+Y+A+T++ GNQ+ +R+ LL EQ +YPP+HY+RRVPQRKVH FT LQL QL +LCA G P PY K+ FP+L++ +P+R+ + PK I Y+D +D
Sbjct: 42 LMNFQEEVRAHRDLNSFLAQASILLDETAASLDEVLRRMLQHV---ARD---GQGSCDQREVISALFTDAGGQEASVHLLTETIQAVTATAT-GVRYQQSWLCVLCNVKSLQRRCVCITRLERPQNWGVNCCEVRFVILILAPPRTKSTKTAIELGRTFATLFSDISFRQKLLETKTQDDFKQELVHQMQLLSSAEH---KASIEEETGPHINKPLKVKEFLQAGRGIYEDLSRRLPYYVSDFTDGMYGSNRSLLKYTTTAIFLYIAILLPAIAFGSLNDESTRGEIDVQKTIVGQSIGGVIYSLLAGSPMVIPITTAPLAIFISVIRGICDDYDLDFPAFYACIGLWNSLFLILGGLFNISLFMKLFKRSTEEVIALFISIAFVGDAVKGTIKIFHKYYHGPTLVNSSAVEIHHLADMIQHPDSSSSSTAPSLSAVLTLCT----RERPILCLLLMLGTLWLGYVLFLIKRSPFLHAKVREVVSDCALPISVVIFSFVGSYLFIDIELPVFNYYNGSIFNIAPLDM--LSGMNVLSACGLGFLLALLIFIDQNIVISLTNAPENRLLKGTAYHWDLMLSGFINILMSVLGLPWMHAAFPHSTLHVRQLAKVEQRVEQGH-LYETIVSVKETRLTSLAANVLIGLSVFLLPVPLQWIPKPVLYGLFLYIALTSIDGNQMCDRIALLLKEQTSYPPTHYIRRVPQRKVHYFTGLQLIQLIILCAFGMYPLPYMKMIFPLLMIFLIPVRNSMLPKIIEAKYLDIID 788
BLAST of slc4a-4 vs. Ensembl Cavefish
Match: ENSAMXT00000047690.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000151.1:229977:263825:-1 gene:ENSAMXG00000011585.2 transcript:ENSAMXT00000047690.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 485.337 bits (1248), Expect = 8.589e-157 Identity = 308/748 (41.18%), Postives = 478/748 (63.90%), Query Frame = 2
Query: 707 IKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIR--ITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-VTTLVNKTVPIVN---------TTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRH 2911
+ +F EVRA D+ FL + ++LD A +D ++ +L+ + A D GQ E +ALF A + S L +T++ + G+ QSW+ +C++ + +R V I RL+ P N G + V FV+L++ P + K TK+ IEL RTFATL SD+ FR +LL +T+D+FK+ L + + L+ + + SI +N+ +E G GI +DL +R+P Y+SD+ DG+ G ++ K + A FLY A LLP++AFG L D++T G+I+V++ I+ Q++GG+ ++L+ G P+++ +TTAPL ++I VI I Y L F ++ +G++NS+FLIL L ++S M+ RSTEE+ ALFISIAF+ DAVK +K+F+K Y TLVN + ++ + + S + +T+ T +E +L LLL++GT+WLG ++PFL++ R +++D +LP++V+I SF+GSYLF DI++ F + F+I ++ +S V +A GL F L+LL F+DQN+ ++ N P N+L KG+AYHWDL++ IN+++S+ GLPW+H PHS LHV+ LA +E+R++ GH +YETIV V+ETRLT L +++LIGLS+ LLP+PL ++P VL GLF+Y+A+T++ GNQ+ +R+ LL EQ +YPP+HY+RRVPQRKVH FT LQL QL +LCA G P PY K+ FP+L++ +P+R+
Sbjct: 42 LMNFQEEVRAHRDLNSFLAQASILLDETAASLDEVLRRMLQHV---ARD---GQGSCDQREVISALFTDAGGQEASVHLLTETIQAVTATAT-GVRYQQSWLCVLCNVKSLQRRCVCITRLERPQNWGVNCCEVRFVILILAPPRTKSTKTAIELGRTFATLFSDISFRQKLLETKTQDDFKQELVHQMQLLSSAEH---KASIEEETGPHINKPLKVKEFLQAGRGIYEDLSRRLPYYVSDFTDGMYGSNRSLLKYTTTAIFLYIAILLPAIAFGSLNDESTRGEIDVQKTIVGQSIGGVIYSLLAGSPMVIPITTAPLAIFISVIRGICDDYDLDFPAFYACIGLWNSLFLILGGLFNISLFMKLFKRSTEEVIALFISIAFVGDAVKGTIKIFHKYYHGPTLVNSSAVEIHHLADMIQHPDSSSSSTAPSLSAVLTLCT----RERPILCLLLMLGTLWLGYVLFLIKRSPFLHAKVREVVSDCALPISVVIFSFVGSYLFIDIELPVFNYYNGSIFNIAPLDM--LSGMNVLSACGLGFLLALLIFIDQNIVISLTNAPENRLLKGTAYHWDLMLSGFINILMSVLGLPWMHAAFPHSTLHVRQLAKVEQRVEQGH-LYETIVSVKETRLTSLAANVLIGLSVFLLPVPLQWIPKPVLYGLFLYIALTSIDGNQMCDRIALLLKEQTSYPPTHYIRRVPQRKVHYFTGLQLIQLIILCAFGMYPLPYMKMIFPLLMIFLIPVRY 772
BLAST of slc4a-4 vs. Ensembl Cavefish
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 471.085 bits (1211), Expect = 2.846e-151 Identity = 300/768 (39.06%), Postives = 482/768 (62.76%), Query Frame = 2
Query: 701 IPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVM-NQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGK-------INVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXM-RWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-VTTLVNKTVPIVNTTLAKGLLNSTNE----FITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
+ + +F E+RA D++ FL+ ++L + +D +++ +LR I + D + E ++LF A + + L++TL+ + G+ QSW+ +C++ + +RHV I+RL P N G + V +V+L++ P K K TK+ +EL RTFA++ SD+ FR +LL ++T++EFKE L L +R T+ ++ + F +G GI +DL +R+P Y SD+ DGI G + K ++ + FLY A LLP++AFG L D++T G+ +V++ I+ Q++GG+ ++L G PL++ LTTAP+ ++I VI I Y L F ++ +G++NS+FLI+ + +LS L+ + RS EE+ ALFISIAF+ DA+K +K+F+K Y TL N ++ +N +N T E FI T + LL LLL++GT+W+G F ++PFL++ R +++D +LP++VLI S++GSY+F DI + F F + +++ ++V +A+GL F L+LL F+DQN+ ++ N P N+L KG+AYHWDL + +IN+++S+ GLPW+H PHS LHV+ LA +EER++ GH +YETIV V+ETR+T L+++ILIG+S+ LLP+PL ++P VL GLF+Y+A+T++ GNQ+ +R+ LL EQ +YPP+HY+R+VPQRK+H FT LQ+ QL LC G P PY K+ FP+L+ + +PIR+ + P+ I Y+D +D
Sbjct: 27 VKLMNFEEEIRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHI---SQDPHTAEPGCNFEEIMSSLFTDAGSQEVNVHLLSETLQCVTATAT-GIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPLKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHLTATKRKTTTVEEEETDPHSHKPLKCRDFFRVGRGIYEDLCRRLPFYPSDFTDGIVGNNKALVKYMTTSIFLYIAVLLPAIAFGSLNDESTRGENSICVSVSDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIIGGVFNLSLLLVKLFKRSIEEVIALFISIAFVADAMKGTVKIFHKYYHAPTLANGSIEELNRISRD--MNLTGELPESFILCT-----RARPLLCLLLMLGTLWVGYTLYQFKRSPFLHAKMREILSDCALPISVLIFSYVGSYVFNDIGLPVFDFHKGPVFRV--APLEKLTGASVLSAMGLGFLLALLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGH-LYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIDGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCTFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIDAKYLDIMD 780
BLAST of slc4a-4 vs. Ensembl Cavefish
Match: slc4a2b (anion exchange protein 2-like [Source:NCBI gene;Acc:103041005]) HSP 1 Score: 205.297 bits (521), Expect = 1.583e-53 Identity = 196/697 (28.12%), Postives = 343/697 (49.21%), Query Frame = 2
Query: 1052 VAIARLKTPVNLGRSSE---GVYFVMLVITPKKEKDTKSDI-ELSRTFATLLSDMEFRSQLLFAQTEDEFKEML--------------------QNHARDLAEEQR--LYRRRSIRITEVMNQAFAYEEKFPLGN---------------GIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYV--TTLVNKTV-------PIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIK-------FVN----FSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
+A RL+ V L E V F+ +++ P T D ++ R+ +TL+SD F A DE +++L + R +A QR L +R ++ + + + EEK L + G++ D+R+R P Y+SD+KD + + ++A F+YFA L P++ FG L + T+G I V +I++ + G+ F L+G QPL+V+ + PL ++ + Y+ L + T W+G + I +++ + S L+R+ +R T+EIF+ IS+ FI + + K+F + + + VN +V P+ N T + NS++ + + LL L+L+ GT ++ Y F + F R ++ D+ +P+A+LIM + Y ++ S FS+ VN Q + + A++ A + +L FM+ +T+ +V+ L KGS +H DLL++ + + +LFGLPW+ S HV AL + + + G + I +V+E R+TGL+ IL+GLS+++ + +PIAVL G+F+YM + +L G QL ER+ LL +P Y+R+V ++HLFT LQ+ L L A+ + A + FP +L+L +P++ ++ P+ S + LD
Sbjct: 485 MAFVRLQEAVELDSVLEVPVPVRFLFVLLGPP---STNMDYHQIGRSISTLMSDKSFHEAAYLA---DERQDLLNAINSFLDCSIVLPPSEMGGEELLRSVAHFQREMLRKREEQEVSLLAKEPKSLEEKGQLADCPEDDPLQRTGRPFGGMIRDIRRRYPKYLSDFKDALNP-----QCMAAVIFIYFAALSPAITFGGLLGEKTEGLIGVSELIVATCIQGVVFCLLGAQPLLVVGFSGPLLVFEEAFYSFCKSNGLEYLTGRVWIGFWLIIIVVVMVAFEGSFLVRFVSRFTQEIFSFLISLIFIYETFSKLAKIFQQHPLQRCSFVNVSVLNESEISPMENFTWSSEATNSSSTIVI----KGEPNTALLSLVLMSGTFFIAFYLRKFKNSAFFPGRLRRVIGDFGVPIAILIMVLV-DYSIQETYTQKLSVPS--GFSVTSPDKRGWIVNPLGSEVQFPVWMMAASVLPALLVFILIFMETQITTLIVSKKERMLIKGSGFHLDLLVIVAMGGICALFGLPWMAAATVRSVTHVNALTVMSKAVAPGDK--PRIQEVKEQRVTGLLVAILVGLSIVIGDLLRQ-IPIAVLFGIFLYMGVMSLNGIQLTERMQLLLMPPKYHPDHTYVRKVRTLRMHLFTALQVVCLAALWAVM---STSASLAFPFVLILTVPLKMFLLPRIFSTREMQCLD 1157
BLAST of slc4a-4 vs. Ensembl Cavefish
Match: slc4a2b (anion exchange protein 2-like [Source:NCBI gene;Acc:103041005]) HSP 1 Score: 201.83 bits (512), Expect = 1.944e-52 Identity = 197/700 (28.14%), Postives = 343/700 (49.00%), Query Frame = 2
Query: 1052 VAIARLKTPVNLGRSSE---GVYFVMLVITPKKEKDTKSDI-ELSRTFATLLSDMEFRSQLLFAQTEDEFKEML--------------------QNHARDLAEEQR--LYRRRSIRITEVMNQAFAYEEK------------------FPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYV--TTLVNKTV-------PIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIK-------FVN----FSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
+A RL+ V L E V F+ +++ P T D ++ R+ +TL+SD F A DE +++L + R +A QR L +R ++ + + + EEK P G G++ D+R+R P Y+SD+KD + + ++A F+YFA L P++ FG L + T+G I V +I++ + G+ F L+G QPL+V+ + PL ++ + Y+ L + T W+G + I +++ + S L+R+ +R T+EIF+ IS+ FI + + K+F + + + VN +V P+ N T + NS++ + + LL L+L+ GT ++ Y F + F R ++ D+ +P+A+LIM + Y ++ S FS+ VN Q + + A++ A + +L FM+ +T+ +V+ L KGS +H DLL++ + + +LFGLPW+ S HV AL + + + G + I +V+E R+TGL+ IL+GLS+++ + +PIAVL G+F+YM + +L G QL ER+ LL +P Y+R+V ++HLFT LQ+ L L A+ + A + FP +L+L +P++ ++ P+ S + LD
Sbjct: 491 MAFVRLQEAVELDSVLEVPVPVRFLFVLLGPP---STNMDYHQIGRSISTLMSDKSFHEAAYLA---DERQDLLNAINSFLDCSIVLPPSEMGGEELLRSVAHFQREMLRKREEQEVSLLAKEPKSLEEKEALLTPFKPEDDPLQRTGRPFG-GMIRDIRRRYPKYLSDFKDALNP-----QCMAAVIFIYFAALSPAITFGGLLGEKTEGLIGVSELIVATCIQGVVFCLLGAQPLLVVGFSGPLLVFEEAFYSFCKSNGLEYLTGRVWIGFWLIIIVVVMVAFEGSFLVRFVSRFTQEIFSFLISLIFIYETFSKLAKIFQQHPLQRCSFVNVSVLNESEISPMENFTWSSEATNSSSTIVI----KGEPNTALLSLVLMSGTFFIAFYLRKFKNSAFFPGRLRRVIGDFGVPIAILIMVLV-DYSIQETYTQKLSVPS--GFSVTSPDKRGWIVNPLGSEVQFPVWMMAASVLPALLVFILIFMETQITTLIVSKKERMLIKGSGFHLDLLVIVAMGGICALFGLPWMAAATVRSVTHVNALTVMSKAVAPGDK--PRIQEVKEQRVTGLLVAILVGLSIVIGDLLRQ-IPIAVLFGIFLYMGVMSLNGIQLTERMQLLLMPPKYHPDHTYVRKVRTLRMHLFTALQVVCLAALWAVM---STSASLAFPFVLILTVPLKMFLLPRIFSTREMQCLD 1165
BLAST of slc4a-4 vs. Ensembl Sea Lamprey
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 538.11 bits (1385), Expect = 3.132e-178 Identity = 324/765 (42.35%), Postives = 485/765 (63.40%), Query Frame = 2
Query: 695 EKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLA---EEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIK--IDTFK---TRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRX-XXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDK 2962
+ + IK+FS EVRA DV++FL + ++LD+ + +++ + H+L + L + + + K K H L++T++ + +N + GL QSW+ +C+ T + R V IARL+ N G + V FV+LV+ P K K TK+ E+ RTFAT+ D+ FR QL+ A++ +EFK L DL EEQ + S+ I Q F +PL GI +D+R+R+P Y SD+ DGI I K + A FLYFACLLPS+AFG L D NT G I+V++ +++Q++GG+ FA++ GQPLIV+LTTAPL LYI I I ++ L F+ ++ +G++NS FL LY+LL +S + S RS EEIFALFISIAF+VDA+KD++K+F ++Y+ N T G + + + ++ LL LLL++GTVWLG F K P+L+ R +++D ++PL+V+ SF+GSY+F+DI + K T SE F++ +N +++ ++ +A+G+ F LS+LFFM+ + +++ N P N+LKKG++YHWDLL+VA++N SLFGLPW+H PHSPLHV+ALA +EER++ GH + ET +TR+ L +L LLP+PL ++P VLDG+F+Y+A+T+L GNQL +R+ LLFTEQ AYPP+HY+RRVPQRK+H FT LQL QL +LC +GF+P PY K+ FP+++L +P+R + PK I Y+D +D+
Sbjct: 1 QSVKIKNFSEEVRAGRDVDRFLSQAAVLLDLPSRSLESTLCHMLESV--LEDNPCAEPREARCSLLKTDCINKVHL-------LSETIQAVTVNPS-GLHYQQSWLCVLCTETTLQHREVCIARLERAQNWGENCCEVRFVILVLAPPKSKSTKTATEVGRTFATIFVDIGFRQQLIEARSPEEFKHALLLRRHDLTAQHEEQEDSSKSSVSIQHPHEQVFG-AVVWPL-MGIWEDIRRRLPYYSSDFTDGILRNRCIGKYIIAMIFLYFACLLPSIAFGSLNDINTRGAIDVQKTLVAQSMGGVLFAVLSGQPLIVLLTTAPLALYIYAIRTICDEFELDFHAYYACIGLWNSFFLTLYALLHMSTRLHLSKRSIEEIFALFISIAFVVDAIKDIIKIFKQNYLPGEPGGCGSAGNNTSDDGWEGAAG--VDSGGPKGSRDVALLALLLMLGTVWLGSTLYQFRKRPYLHLQAREILSDCAMPLSVIAFSFLGSYVFRDIDRMVTGLKFSYTPSESYFALAPLNL--LTVGSICSAMGIGFLLSILFFMEHTMAASLTNAPHNRLKKGTSYHWDLLLVAVLNATFSLFGLPWMHAAFPHSPLHVRALATVEERVEDGH-VDETQGNSLKTRVPVLLAHMLLGLSLFFLLPLPLQWIPRPVLDGIFLYIALTSLDGNQLFQRLALLFTEQTAYPPTHYVRRVPQRKIHYFTGLQLLQLAVLCGVGFSPIPYMKMVFPVIMLAALPVRFFAVPKIIESRYLDVMDE 748
BLAST of slc4a-4 vs. Ensembl Sea Lamprey
Match: SLC4A2 (solute carrier family 4 member 2 [Source:HGNC Symbol;Acc:HGNC:11028]) HSP 1 Score: 183.726 bits (465), Expect = 1.312e-47 Identity = 177/652 (27.15%), Postives = 315/652 (48.31%), Query Frame = 2
Query: 1166 ELSRTFATLLSDMEF---------RSQLLFAQTE---------------DEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFP------------------LGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIV-NTTLAKGLLNST--NEFITITTEESRKENGXXXXXXXI-GTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFI-----GSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLF---FMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
E+ R+ +TL+SD +F R LL A TE D + RD+ +++R S ++ V A + P L G+V D R+R P Y+SD +D + + ++A F+YFA L P++ FG L + T G + V +I+S + G+ FAL+G QPL+++ + PL ++ + ++ + + + T W+G + + ++L + S ++R+ +R T+EIF++ IS+ FI + + KVF + + T P++ N T NS+ N T + + N L LLL+ GT ++ + F + FL R ++ D+ +P+A+L+M + +Y K D F S + V+ P L+F FM+ +T+ +V+ L KGS +H DLL++ ++ + ++FGLPW+ S HV AL + + G + I V+E R+TGL+ I++GLS++L + +P+AVL G+F+YM +T+L G Q +R++L+F +P + Y +V +++L+T +Q LG L A+ + A + FP +L+L +P+R ++ + + + LD
Sbjct: 356 EIGRSISTLMSDKDFHEAAYVADERQDLLNAMTEFLDVSIVLPPSELTDDGLLRSVAAFQRDMLQKRR-QEDESKKLNIVPTSAELKQTAVPSQRKEDDDPDDPLRRSGRLFGGLVRDARRRYPHYLSDLRDALNP-----QCLAAVIFIYFAALSPAITFGGLLSEKTQGLMGVSELIISTCLQGILFALLGAQPLLIIGFSGPLLVFEEAFFSFCSSQGVEYLTGRVWIGFWMVLIVLLLVAFEGSFMVRFISRFTQEIFSILISLIFIYETFSKLYKVFQDHPLLS----TYPVISNMTTNSDTSNSSIVNGTTAATPKVLNQPNTALLSLLLMSGTFFIAFFLRKFKNSRFLAGKVRRVIGDFGVPIAILVMVLVDFGVPNTYTQKLNVPDGFSVTSPSKRGWVINPLGAEGTFPVWLMFACVIPGLLVFILIFMESQITTLIVSKKERMLLKGSGFHLDLLLIVVMGAICTIFGLPWLTAATVRSVTHVNALTVMSKATAPGDK--PRIECVKEQRITGLLVAIIVGLSMVLGQVLRQ-IPLAVLFGIFLYMGVTSLNGIQFYDRLMLVFMPAKYHPDTAYATKVRTLRMNLYTGIQFVCLGGLWAVM---STAASLAFPFVLILTVPLRRFLLSRIFTDRELKCLD 991
BLAST of slc4a-4 vs. Ensembl Sea Lamprey
Match: SLC4A2 (solute carrier family 4 member 2 [Source:HGNC Symbol;Acc:HGNC:11028]) HSP 1 Score: 171.014 bits (432), Expect = 1.843e-43 Identity = 184/662 (27.79%), Postives = 315/662 (47.58%), Query Frame = 2
Query: 1166 ELSRTFATLLSDMEF---------RSQLLFAQTE--------------DEF---------KEMLQNHARDLAEEQRLYRR-----RSIRITEVMNQAFAYEEKFPLG------NGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLA-KGLLNSTNEFITITTEESRKENGXXXXXXX------------IGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGS-----YLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLF---FMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
E+ R+ +TL+SD +F R LL A TE DE ++MLQ E+ R + R +S R V Y+ + PL G+V D R+R P Y SD KD + + ++A F+YFA L P++ FG L + T G I V +I+S ++ + FAL+ QPL+++ + PL ++ + ++ + + T W+G + + ++L + S L+R+ +R T+EIF++ ISI FI + + KVF + + KT I T LA G+ + + I T +R + + GT ++ + + FL R ++ D+ +P+A+LIM + S Y K D F S ++ S S V+ P +L+F FM+ +T+ +V+ +L KGS +H DLL++ ++ +L G+PW+ S HV AL + + G + I V+E R TGL+ +LIGLS++L + +P+AVL G+F+YM +T++ G Q+ +R++L F +P S Y +V +++++T +Q L LL + + A + FP +L+L +P+RH++ P+ + + LD
Sbjct: 569 EIGRSISTLMSDKDFHEAAYLADERQDLLTAITEFLDCSIVLPPSELTDEGLLRSVAAFQRDMLQKRRE---EDGRRHPREEPPVQSTRGALVGGGVRLYDVEDPLQRTGRPFGGVVRDARRRYPFYPSDIKDAVDP-----QCLAAVIFIYFAALSPAITFGGLLGEKTQGLIGVSELIISTSIQSIFFALLSAQPLLIVGFSGPLLVFEEAFFSFCWSQDVEYLTGRLWIGFWLILIVLLTVAFEGSFLVRYISRFTQEIFSILISIIFIYETFYKLFKVFKEHPLL----KTYTIGGTDLAGSGVWGNASMVIGSATAAARNDTDAPTKMPSQPNTSLLSLVLMSGTFFIAFFLRKLKNSRFLAGKVRRVIGDFGVPIAILIMVLVDSAIPDTYTQKLAVPDGFSVTSPDQRSWLVNPLGVRSTFPVWMMFACVVPAALVFILIFMETQITTLIVSKSERRLVKGSGFHLDLLLIVLMGGASALLGVPWLTAATVRSVTHVNALTVMSKATAPGEK--PRIECVKEQRATGLLVAVLIGLSVVLGEVLRR-IPLAVLFGIFLYMGVTSVNGIQMYDRLLLAFMPAKHHPDSAYASKVKTWRMNMYTAIQFVCLALLWVVM---STAASLAFPFVLILTVPLRHFLLPRIFTAHELRCLD 1212
BLAST of slc4a-4 vs. Ensembl Sea Lamprey
Match: slc4a7 (solute carrier family 4 member 7 [Source:ZFIN;Acc:ZDB-GENE-140106-104]) HSP 1 Score: 168.318 bits (425), Expect = 1.191e-42 Identity = 153/552 (27.72%), Postives = 260/552 (47.10%), Query Frame = 2
Query: 1376 NGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKV-------------FYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFI---TITTEESRKENGXXXXXXX------------------IGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVN----FSQISISAVFAALGLAFP---LSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIR 2908
G+V D++++IP Y SDY+D + + +++ FLY AC+ P + FG L + T+G+I+ + ++ G+ ++L GQPL ++ +T P+ ++ K++Y Y+L + ++ + +G++ + +L D S L+ + TR TEE FA I I FI +A++ ++ + Y V +VP T A +N + + I +T + + +G T +L + F + + R ++D+++ L +L M I +L I + K + EF + I + + L A P ++L FMDQ +T+ ++N +KLKKG YH DLL VAI+ V S+ GLPW S HV +L E G + + +RE R + ++ + + L ++P+ VL G+F+YM ++L G Q +R+ L P YLR VP RKVHLFT +Q T L LL + +P A I FP+++L + IR
Sbjct: 487 GGLVRDIKRKIPFYWSDYRDSLN-----LQCIASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCKDYNLSYLSLRACIGLWTAFLCLLLVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLVHLGETYEVNMHADPELLTQYSCVCVEPSVPSNETLDAWSNMNRSADSIPWGNLTVSKCLELHGQFVGTACGHHGPYIPDVLFWSIILFFATFFLSGFLKQFKTMRYFPTKVRSTVSDFAVFLTILSMVVIDYFL----GIPSPKLQVPSEFKPTRDDRGWIVDPIGPNPWWTILAAAIPALLCTILVFMDQQITAVIINRKEHKLKKGCGYHLDLLWVAIMLAVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQ--PKFLGIREQR-VTGLMIFVLMGCSVFMTGVLKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFVMPAKHQPDFIYLRHVPLRKVHLFTAVQFTCLVLLWVIKASP---AAIVFPMMVLALVFIR 1023
BLAST of slc4a-4 vs. Ensembl Sea Lamprey
Match: SLC4A4 (solute carrier family 4 member 4 [Source:HGNC Symbol;Acc:HGNC:11030]) HSP 1 Score: 129.413 bits (324), Expect = 5.114e-32 Identity = 125/436 (28.67%), Postives = 204/436 (46.79%), Query Frame = 2
Query: 1370 LGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVF--------YKSYVTTLVNKTVPIVNTTL--AKGLLNSTN-EFITITTEESRKENGXXXXXXX--------------IGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEF---SIK---FV------NFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETR 2566
L G+ D+++++P + SD D + +I+ L SA F+Y A + ++ FG L TD V L + G F L GQPLI++ +T P+ ++ ++++ S + + W+G++++ ++ D S L+++ TR TEE F+ IS FI DA+K +L +F YK TL + T + L L N+T ++ ++ +E K G L +GT + + F + ++ R L++D+S+ L+ I +F+G + I ++T K EF S K FV + +SAV A L +++L FMDQ +T+ +VN NKLKKGS YH DL VA++ S GLPW S H+ +L E G + + VRE R
Sbjct: 2 LFGGLFKDIKRKLPFFCSDIYDAL----SIQSL-SATLFIYLATITNAITFGGLLGDATDNMQGVLESFLGTALSGAVFCLFAGQPLIILSSTGPVLVFERLLFNFSKENDFDYLEFRLWIGLWSAFMSLILVATDASYLVQYFTRFTEEGFSALISFIFIYDAIKKMLGLFNYYPINLDYKPDYITLYSCTCQAPDPVLMIKPDLGNATGPDWSALSKKECSKYGGSLSGKACKFVPDVALVSLLLFMGTYYTTMALKRFKTGRYFPTTIRKLISDFSIILS--IFTFVGLDIL--IGLETPKLVVPTEFKPTSAKRGWFVPPFGGNPWWVYLVSAVPAIL-----ITILVFMDQQITAIIVNRKENKLKKGSGYHLDLFWVAVLMATCSFLGLPWYVAATVLSIAHIDSLKMETETSAPGEQ--PKFLGVREQR 421
BLAST of slc4a-4 vs. Ensembl Yeast
Match: BOR1 (Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1 [Source:SGD;Acc:S000005219]) HSP 1 Score: 153.68 bits (387), Expect = 1.653e-39 Identity = 127/470 (27.02%), Postives = 219/470 (46.60%), Query Frame = 2
Query: 1355 EEKFP-LGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMS---FIGSYL----FKDIKIDT--FKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTE 2734
+FP LG GI DL+ RIP Y SD+ D +++ + YF LLP++AF TD V V+LS + G+ F ++GGQPL ++ T P++++ +Y I + ++ W+ +++ IF ++ + + L+++ T +IF LFI++ +I KG+ T +F + E+S ++ ++ L+ T + G++F F P + R ++DYS L+VL S G YL FK + I F T ++ + I + VF AL L++LF+ D NV+S M KLKK S++H+D ++ + + + G+P +G +P +PLH + L DS ++ I V + +++G L + L +P AVL GLF M I L N +++R++ LF++
Sbjct: 52 RRRFPTLGIGIWLDLKDRIPYYKSDWVDAFN-----YRVIPSIVDTYFNNLLPAIAFAQDMFDRTDNSYGVNEVLLSSAMAGIVFGVLGGQPLCIVGVTGPISIFNYTVYEIIKPLNTSYFGFMFWICMWSMIFHLVLAFTNAVCLLQYVTTFPCDIFGLFINVVYI-------------------------------QKGIQILTRQFSAKSGEKSVQDGFASVVVALVMTAF-GLFFKLFHYYPLFSHRIRTFISDYSTALSVLFWSSFTHFGGYLHDVKFKKLPITKAFFPTSKVNRPQNTWLAYEPIPVKDVFIALPFGIFLTILFYFDHNVSSLMAQRHQYKLKKPSSFHYDFALLGLTTCISGVLGIPAPNGLIPQAPLHTETLLVR----DSNQKV---ISCVEQRFTNTFQGLMILGTMTRPLLVCLGEIPQAVLSGLFFIMGINGLMTNSIIQRLVFLFSD 477
BLAST of slc4a-4 vs. Ensembl Nematostella
Match: EDO40610 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6T5]) HSP 1 Score: 308.531 bits (789), Expect = 1.970e-96 Identity = 193/318 (60.69%), Postives = 251/318 (78.93%), Query Frame = 2
Query: 2006 KENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
+E G L+LLL +GTV LG+ NF K+PFL+++KR +ADY+LP+AVL SFIG+Y F + TFK S ++K + S +S AVF A GL F LSLLFFMDQN++SAMVN P N+LKKGSA+H DLL+VAIIN +LS FGLPW+HG LPHSPLHV+ALAD+EER+D GH +++ IVKVRETRLT LI+HILIGLSLL+LP PL Y+P AVLDGLF+++A+T+L NQ+ ER++L TEQ+AYPP+HY+RRVPQRK+H +T +Q+ QLG+LC GF+P PY K+ FP+LLLL +PIRH + P+ I ++DA+D
Sbjct: 6 REAGTLYLLLSLGTVLLGVTLYNFKKSPFLDANKREALADYALPVAVLFFSFIGTYFFSGESLHTFK--SSGAVTLKPSSLSLLSAGAVFGACGLGFCLSLLFFMDQNISSAMVNNPGNRLKKGSAFHLDLLVVAIINGILSAFGLPWIHGALPHSPLHVRALADVEERVDQGH-VFDIIVKVRETRLTTLIAHILIGLSLLMLPTPLDYIPTAVLDGLFLFVAVTSLDDNQMFERLLLFVTEQSAYPPNHYIRRVPQRKMHAYTGMQMLQLGILCGFGFSPMPYLKMVFPVLLLLLLPIRHLVVPRVIERKFLDAID 320
BLAST of slc4a-4 vs. Ensembl Nematostella
Match: EDO40611 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6T6]) HSP 1 Score: 254.218 bits (648), Expect = 1.237e-72 Identity = 139/347 (40.06%), Postives = 222/347 (63.98%), Query Frame = 2
Query: 677 LVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQ-------RLYRRRSIRITEVMNQAFAYEEKFPL--GNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAIS 1690
L+L + +KI +K+FS+EVRA D+++FL++ ++L++ ++ I++ +L +I D + +++ + A+ A F K S L+ ++G I+E G Q+W+ AM L + + H+A++RL+ NLGR+ +G + V+L+++P K K TK+ +EL RTFATLLSD++FR LL A++++EF ++L DL+ + +L R S + F ++E + GI DD +R+P Y+SD+KDG+ G T+ KLVS FLYFAC+LPS+AFGVL +NT GK++V++V++SQ GGL F+L+GGQPLI++LTTAPL LYIK + A S
Sbjct: 14 LMLVKHQKIDMKNFSTEVRARKDIDRFLEKPTVLLNVHKTKIEDIIDLMLDKIIE---DKQLQKVN--FSAARTAFFTKD-----SVHCLSHVIQGTEISEGGGWEETQNWLVAMADLPSIQQSHIAMSRLRHATNLGRTLQGTHLVVLILSPVKTKKTKNSLELGRTFATLLSDIDFRQSLLEAESKEEFVKVLAERKSDLSNNRNKPEINSKLVRSASKGFNP-YHCVFNFQETSTMKPCRGIRDDFMRRMPHYLSDFKDGVVGHRTLFKLVSTVIFLYFACILPSVAFGVLNSKNTKGKMDVQKVLVSQVFGGLFFSLLGGQPLIILLTTAPLALYIKDLTAGS 349 HSP 2 Score: 193.741 bits (491), Expect = 7.222e-52 Identity = 143/289 (49.48%), Postives = 180/289 (62.28%), Query Frame = 2
Query: 2057 GIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPS---NKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVY--MAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIR 2908
G+ NF K+PFL+++KR +ADY+LP+AVL SFIG+Y F D +V C S +LKKGSA+H DLL+VAIIN +LS FGLPW+HG LPHSPLHV+ALAD+EER+D GH +++ IVKVRETRLT LI+HILIGLSLL+LP PL Y+P AVLDGL + AL N F Q+AYPP+HY+RRVPQRK+H +T +Q+ QLG+LC GF+P PY K+ FP+LLLL +PIR
Sbjct: 423 GVTLYNFKKSPFLDANKREALADYALPVAVLFFSFIGTYFFSGESCDIV---------------------------------------------VVVLCSSTHIQELKKGSAFHLDLLVVAIINGILSAFGLPWIHGALPHSPLHVRALADVEERVDQGH-VFDIIVKVRETRLTTLIAHILIGLSLLMLPTPLDYIPTAVLDGLASSHNAQVFALLENN-------CFLLQSAYPPNHYIRRVPQRKMHAYTGMQMLQLGILCGFGFSPMPYLKMVFPVLLLLLLPIR 658
BLAST of slc4a-4 vs. Ensembl Nematostella
Match: EDO45844 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRK7]) HSP 1 Score: 202.601 bits (514), Expect = 1.622e-53 Identity = 179/632 (28.32%), Postives = 299/632 (47.31%), Query Frame = 2
Query: 1025 SLTCVHKRHVAIARLKTPVNLGRSSE---GVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARD------------------LAEEQRLYRRR--SIRITEVMNQAFAYEEKFPL------GNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKI-------DTFKTRSEEEFSIK---FVN----FSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVH 2791
+L C+ A RL LG +E V F+ +++ P+ + DT E+ R+ ATL+SD F ++++ ++ + D L++ + + +RR + I + QA A EE PL G++ D++ R YISD+KDG + + FLYFA P++AFG L + TD + V VI + GL FAL GQPLI++ T P+ ++ + I+ + ++ F W+G + + L L + L+R+ TR TEE+FA IS+ FI +A+ + KVF K+ ++ P+ N T + + +T E + LL +L+ GT ++ Y F + F R L++D+ + +A++ M I + +D I D K K F+N + VFAA+ A + +L FM+ +T ++N N L+K Y+ DLL++ +I L+ SLFGLPW+ S H AL+ G + Y +V+VRE R I ++ +LL L +VP+ VL G+ +Y+ +++L QL+ R+I++ +P Y+R+VP K+H
Sbjct: 249 TLDCLKNPVTAFVRLAKGCYLGNVTEVAIPVRFLFVMLGPETQSDTYH--EIGRSIATLMSDQVFHDLAYYSESREDILMAINEFLDDTVVLPPGEWDKQLLIPVLLSQSKTMAKRRKQAKEINAIATQA-AEEEDNPLKRTGRFCGGLIQDIKHRSKTYISDFKDGFNW-----QCLLVTVFLYFAVFAPNVAFGGLLAEKTDQWLGVSEVIFASCFCGLLFALFSGQPLIIIGATGPVMVFEQTIFKFCEQSNIEFLPWRCWIGFWVLVILFLVVAFEGCFLVRYFTRFTEELFACLISLIFIYEAINFLYKVFKKNPLS-----RDPVTNLTNIDPYIKEN--IVPVTGEPN---TALLCAILMFGTYFVAFYMRKFRNSHFFGKKARRLVSDFGIAIAMITMVIIDVAI-RDTVITPKISIGDVTKVGFHPTLKTKRGWFINPMGLVDSMKAGWVFAAIIPALFVGILLFMETELTGVLINKKENCLQKRPGYNMDLLLMGVITLICSLFGLPWMCPATVRSVSHFNALSVWSTSHAPGEKPY--LVEVREQR-ITNILIHVLTGMSILLAPVLHHVPVPVLFGVLLYLGLSSLSNLQLINRLIMMLMPPKHHPDVRYVRKVPTAKIH 858
BLAST of slc4a-4 vs. Ensembl Nematostella
Match: EDO31793 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWX4]) HSP 1 Score: 165.622 bits (418), Expect = 8.703e-42 Identity = 173/632 (27.37%), Postives = 291/632 (46.04%), Query Frame = 2
Query: 1052 VAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDI-ELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARD--------------------LAEEQR--LYRRRS-----------IRITEVMNQAFAYEEKFPL------GNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTV---PIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFI----GSYLFKDIKI-DTFKTRSEEEFSIKFVN----FSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVH 2791
V +AR NL + V F+ +++ P D D E+ R ATL+SD F A+ + + + + D LA+E + RRR + E + ++ E+ PL G++ D+++R P Y SD D + V A +Y ACL P+++FG L + T G + V +I+S + G+ FAL GQPLI++ T PL L+ ++ +S + + +WVGI+ + ++ L+R+ TR TEEIFA IS+ FI D +K + +F +T+ + V + NT L F TI L GT ++ + + FLN + R +++D+ + +A++ M + S + + + D F S +VN ++ A+F AL A +S+L FM+ + +++ N+LKKG Y+ DL +V + + S+ GLPW+ T H+ H+ AL G + +++V+E R+T +I H+LIGL++LL P+ + P+ VL G+FV++ ++L Q VER LLF +P Y+R V K++
Sbjct: 222 VRLARGCRLRNLAEVNIPVRFLFILLGPD---DKSIDYHEVGRCVATLMSDRLFLDCAYDAEELQDLYDAMDSFLSDTVIIPPGEWDRNVLAQSLPSLAKETKKTALRRRGALLRKQRHFSDLETQETVTESLELEDD-PLKRTGLFCGGLLRDVKRRFPYYKSDMTDSFNW-----RCVMATILVYVACLAPAISFGGLLYKKTKGWMGVAEMIVSTALSGVIFALFAGQPLIIIGATGPLLLFETNVFNLSESFDFEYMPWRAWVGIWVMLICWALVAMEGCFLIRYFTRFTEEIFACMISLIFIYDGIKYIYDIFGLYPLTSGTTENVDGKDVSNTAL----------FTTI---------------LFFGTFFVAHIIRDVRHSRFLNHTLRRVISDFGVLIAIVAMILVELSAQSIYVQRLNVPDGFDVTS-PHLRGWYVNPMGTERRLGADAIFGALVPAILVSILVFMEVEFCNVILDKKDNQLKKGPGYNLDLFVVGFLMGMCSVLGLPWMCATPVHTVSHLHALMVHSTNHAPGE--HPQLLEVKEQRVTNIIIHVLIGLTMLLAPVIRL-TPVVVLFGVFVHLGFSSLSHLQFVERFKLLFVSPNHHPDRRYVRSVSTGKMN 815
BLAST of slc4a-4 vs. Ensembl Nematostella
Match: EDO27089 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TA82]) HSP 1 Score: 62.003 bits (149), Expect = 1.323e-11 Identity = 32/104 (30.77%), Postives = 60/104 (57.69%), Query Frame = 2
Query: 1574 ILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVF 1885
+L +GG+ FAL GQPLI++ T P+ ++ +++Y + L + + W+GI+ +F ++ + D S ++ + TR TEE FA I+I +I + K + +
Sbjct: 5 MLGGAIGGILFALFSGQPLIILGATGPMLVFEEIVYTFCERVGLEYLSFRLWIGIWTMLFCLILVVTDASAMICYFTRFTEETFATLIAIIYIYEGFKKLFHIL 108
BLAST of slc4a-4 vs. Ensembl Medaka
Match: slc4a11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:101165271]) HSP 1 Score: 520.776 bits (1340), Expect = 1.306e-169 Identity = 325/846 (38.42%), Postives = 519/846 (61.35%), Query Frame = 2
Query: 482 FKKQSTNNDDKDSKDRNLLLSPTNYINRQISETSEMSTDTV----SNFSIGSLARYYRTADENGEGLPCLVLARLEK-IPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEML--QNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-VTTLVNKTVPIV-----------NTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
F+KQ D+ S+DR + ++ D + + S G+ AD+ G C++L + + + +F EVRA D++ FL + ++LD A +D +++ +L + D + E + LF A + + L++T++G+ G+ QSW+ +C++ + +RHV I+RL+ P N G + V +V+L++ P K K TK+ +EL RTFATL SD+ FR +LL +T++EFKE L Q H A +Q + ++ ++ F +G GI +D +R+P Y SD+ DGI G T+ K ++ A FLY A LLP++AFG L D++T G+I+V++ I+ Q++GG+ ++L G PL++ LTTAPL ++I VI I Y+L F ++ +G++N +FLIL + ++S LM+ RSTEE+ ALFISIAF+VDAVK +K+F + Y T N+++ + A+ +LN+ E I + +E +L LLL++GT+W+G F ++PFL++ R +++D +LP++VL+ SFIGSY+F DI++ FK + F++ F ++S V +A+GL F L+LL F+DQN+ ++ N P N+L KG+AYHWDL++ +IN+++S+ GLPW+H PHS LHV+ LA +E+R++ GH +YETIV+V+ETRLT L ++I IG+SLLLLP+PL ++P VL GLF+Y+A+T++ GNQ+ +R+ LL EQ +YPP+HY+R+VPQRK+H FT LQ+ QL +LC G P PY K+ FP++++ +PIR+ + P I Y+D +D
Sbjct: 26 FQKQREAEQDEGSEDRE-----------ETQDSPIACGDDIHLYDNQISPGT------DADDCG----CVLLNTSRRYVKLMNFEEEVRALRDLDGFLAKASILLDETAASLDDVLKRMLHHV---GQDGHAYEPSCNFEEVMSLLFTDAGAQEVNVHLLSETIQGVTATAT-GIQYQQSWLCILCNVKHLQRRHVCISRLERPQNWGENCCEVRYVILILAPSKMKSTKTAMELGRTFATLFSDISFRQKLLETKTQEEFKEALLFQRHQLTAANQQPTALGKE-ETDPRSHKPLKCKDFFKVGRGIYEDFCRRLPFYPSDFTDGIVGSNKTLLKYMTTAIFLYIAILLPAIAFGSLNDESTRGEIDVRKTIVGQSIGGIIYSLFAGSPLVIPLTTAPLAIFISVIRGICDDYNLDFPAFYACIGLWNCLFLILGGIFNVSLLMKLFKRSTEEVIALFISIAFVVDAVKGTVKIFQRYYNAPTSTNRSLEDFRQGGELLEGNRSEVAARLMLNALPETII----QCSRERPVLCLLLMLGTLWMGYTLYQFKRSPFLHAKVREVLSDCALPISVLLFSFIGSYIFSDIELPVFKVHNRPIFNV--APFERLSAMNVVSAMGLGFLLALLIFIDQNIVVSLTNAPENRLLKGTAYHWDLMLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAFVEQRVEGGH-LYETIVQVKETRLTSLAANIFIGVSLLLLPVPLQWIPKPVLYGLFLYIALTSIDGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMMQLLVLCTFGMYPIPYMKMIFPLVMIFLIPIRNNVLPHIIEAKYLDIMD 838
BLAST of slc4a-4 vs. Ensembl Medaka
Match: slc4a11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:101165271]) HSP 1 Score: 520.776 bits (1340), Expect = 1.400e-169 Identity = 315/787 (40.03%), Postives = 500/787 (63.53%), Query Frame = 2
Query: 647 ADENGEGLPCLVLARLEK-IPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEML--QNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-VTTLVNKTVPIV-----------NTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
AD+ G C++L + + + +F EVRA D++ FL + ++LD A +D +++ +L + D + E + LF A + + L++T++G+ G+ QSW+ +C++ + +RHV I+RL+ P N G + V +V+L++ P K K TK+ +EL RTFATL SD+ FR +LL +T++EFKE L Q H A +Q + ++ ++ F +G GI +D +R+P Y SD+ DGI G T+ K ++ A FLY A LLP++AFG L D++T G+I+V++ I+ Q++GG+ ++L G PL++ LTTAPL ++I VI I Y+L F ++ +G++N +FLIL + ++S LM+ RSTEE+ ALFISIAF+VDAVK +K+F + Y T N+++ + A+ +LN+ E I + +E +L LLL++GT+W+G F ++PFL++ R +++D +LP++VL+ SFIGSY+F DI++ FK + F++ F ++S V +A+GL F L+LL F+DQN+ ++ N P N+L KG+AYHWDL++ +IN+++S+ GLPW+H PHS LHV+ LA +E+R++ GH +YETIV+V+ETRLT L ++I IG+SLLLLP+PL ++P VL GLF+Y+A+T++ GNQ+ +R+ LL EQ +YPP+HY+R+VPQRK+H FT LQ+ QL +LC G P PY K+ FP++++ +PIR+ + P I Y+D +D
Sbjct: 70 ADDCG----CVLLNTSRRYVKLMNFEEEVRALRDLDGFLAKASILLDETAASLDDVLKRMLHHV---GQDGHAYEPSCNFEEVMSLLFTDAGAQEVNVHLLSETIQGVTATAT-GIQYQQSWLCILCNVKHLQRRHVCISRLERPQNWGENCCEVRYVILILAPSKMKSTKTAMELGRTFATLFSDISFRQKLLETKTQEEFKEALLFQRHQLTAANQQPTALGKE-ETDPRSHKPLKCKDFFKVGRGIYEDFCRRLPFYPSDFTDGIVGSNKTLLKYMTTAIFLYIAILLPAIAFGSLNDESTRGEIDVRKTIVGQSIGGIIYSLFAGSPLVIPLTTAPLAIFISVIRGICDDYNLDFPAFYACIGLWNCLFLILGGIFNVSLLMKLFKRSTEEVIALFISIAFVVDAVKGTVKIFQRYYNAPTSTNRSLEDFRQGGELLEGNRSEVAARLMLNALPETII----QCSRERPVLCLLLMLGTLWMGYTLYQFKRSPFLHAKVREVLSDCALPISVLLFSFIGSYIFSDIELPVFKVHNRPIFNV--APFERLSAMNVVSAMGLGFLLALLIFIDQNIVVSLTNAPENRLLKGTAYHWDLMLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAFVEQRVEGGH-LYETIVQVKETRLTSLAANIFIGVSLLLLPVPLQWIPKPVLYGLFLYIALTSIDGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMMQLLVLCTFGMYPIPYMKMIFPLVMIFLIPIRNNVLPHIIEAKYLDIMD 840
BLAST of slc4a-4 vs. Ensembl Medaka
Match: slc4a11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:101165271]) HSP 1 Score: 511.916 bits (1317), Expect = 4.321e-166 Identity = 316/798 (39.60%), Postives = 503/798 (63.03%), Query Frame = 2
Query: 647 ADENGEGLPCLVLARLEK-IPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKA-------HYENFSY----QRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEML--QNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSY-VTTLVNKTVPIV-----------NTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
AD+ G C++L + + + +F EVRA D++ FL + ++LD A +D +++ +L + D + E + LF A + ++F + L++T++G+ G+ QSW+ +C++ + +RHV I+RL+ P N G + V +V+L++ P K K TK+ +EL RTFATL SD+ FR +LL +T++EFKE L Q H A +Q + ++ ++ F +G GI +D +R+P Y SD+ DGI G T+ K ++ A FLY A LLP++AFG L D++T G+I+V++ I+ Q++GG+ ++L G PL++ LTTAPL ++I VI I Y+L F ++ +G++N +FLIL + ++S LM+ RSTEE+ ALFISIAF+VDAVK +K+F + Y T N+++ + A+ +LN+ E I + +E +L LLL++GT+W+G F ++PFL++ R +++D +LP++VL+ SFIGSY+F DI++ FK + F++ F ++S V +A+GL F L+LL F+DQN+ ++ N P N+L KG+AYHWDL++ +IN+++S+ GLPW+H PHS LHV+ LA +E+R++ GH +YETIV+V+ETRLT L ++I IG+SLLLLP+PL ++P VL GLF+Y+A+T++ GNQ+ +R+ LL EQ +YPP+HY+R+VPQRK+H FT LQ+ QL +LC G P PY K+ FP++++ +PIR+ + P I Y+D +D
Sbjct: 70 ADDCG----CVLLNTSRRYVKLMNFEEEVRALRDLDGFLAKASILLDETAASLDDVLKRMLHHV---GQDGHAYEPSCNFEEVMSLLFTDAGAQEVNDNSQSFVFFDDVHLLSETIQGVTATAT-GIQYQQSWLCILCNVKHLQRRHVCISRLERPQNWGENCCEVRYVILILAPSKMKSTKTAMELGRTFATLFSDISFRQKLLETKTQEEFKEALLFQRHQLTAANQQPTALGKE-ETDPRSHKPLKCKDFFKVGRGIYEDFCRRLPFYPSDFTDGIVGSNKTLLKYMTTAIFLYIAILLPAIAFGSLNDESTRGEIDVRKTIVGQSIGGIIYSLFAGSPLVIPLTTAPLAIFISVIRGICDDYNLDFPAFYACIGLWNCLFLILGGIFNVSLLMKLFKRSTEEVIALFISIAFVVDAVKGTVKIFQRYYNAPTSTNRSLEDFRQGGELLEGNRSEVAARLMLNALPETII----QCSRERPVLCLLLMLGTLWMGYTLYQFKRSPFLHAKVREVLSDCALPISVLLFSFIGSYIFSDIELPVFKVHNRPIFNV--APFERLSAMNVVSAMGLGFLLALLIFIDQNIVVSLTNAPENRLLKGTAYHWDLMLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAFVEQRVEGGH-LYETIVQVKETRLTSLAANIFIGVSLLLLPVPLQWIPKPVLYGLFLYIALTSIDGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMMQLLVLCTFGMYPIPYMKMIFPLVMIFLIPIRNNVLPHIIEAKYLDIMD 851
BLAST of slc4a-4 vs. Ensembl Medaka
Match: SLC4A11 (sodium bicarbonate transporter-like protein 11 [Source:NCBI gene;Acc:101168050]) HSP 1 Score: 447.588 bits (1150), Expect = 1.266e-143 Identity = 275/684 (40.20%), Postives = 414/684 (60.53%), Query Frame = 2
Query: 1037 VHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAE----------EQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPG-TIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITIT-------TEESRKENGXXXXXXXIGTVWL-------------------------GIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
+ +R V IARL P N G + +V+L++ P + K TK+ IEL RTFAT+ SD+ FR +LL +T+DEFK+ L + R L+E E+ RR + + F G G+ +DLR+R+P+Y SD+ DGI G + K ++ A FLY A LLP++AFG L D++T G+I+V++ I+ Q++GG+ ++L G PL++ LTTAPL ++I +I I Y+L F ++ +G++N FL+L L ++S LM+ RSTEE+ ALFISIAF+ DA+K +K+F + PI+ TT + +L NE + TE + + V+L G ++P+LN R +++D +LP++V+I SFIGSYLF DI++ F F K+ F ++S AV +A+GL F L+LL F+DQN+ ++ + P +KL KG+ +HWDL++ IN+++S GLPW+H PHS LH + LA +E +++GH ++ TIV V+ETR+T L+++ILIGLS +LPIPL ++P VL GLF+Y+A T+L GNQ+V+R+ LL EQ +YPP+HY+RRVPQRKVH FT LQ+ QL +LCA G P PY K+ FP+L++L +P+R + P+ I Y+D +D
Sbjct: 18 LQRRQVCIARLDKPQNWGVNCAEARYVILILAPPRTKSTKTAIELGRTFATMFSDISFREKLLDPRTQDEFKQELVSQRRQLSEVNANTIVEEVEESDPRR---------GKPLECRDFFKAGRGVYNDLRRRLPLYPSDFTDGITGKDRCLVKYITTAIFLYIAILLPAIAFGSLNDESTRGEIDVQKTIVGQSIGGVIYSLFAGSPLVIPLTTAPLAIFISIIRGICDDYNLDFEAFYACIGLWNCFFLVLGGLFNVSLLMKLFKRSTEEVIALFISIAFVGDAIKGTIKIFDHYFHG-------PILATTNSSAVLQQINEILEKANNQTPHLTEHHKGDMSQFEQAETQVLVFLPETLVICTRERPILCLLLMLGTLWLGYALYLMKRSPYLNDKIREVVSDCALPISVMIFSFIGSYLFIDIQLPVFNVHDGPVF--KYPEFEKLSGMAVLSAVGLGFLLALLIFIDQNIVISLTHVPEHKLLKGTTFHWDLVLTGFINILMSCLGLPWMHAAFPHSSLHARQLAKVEHHLENGH-LHSTIVSVKETRVTSLVANILIGLSAFMLPIPLQWIPKPVLYGLFLYVAATSLDGNQMVDRMTLLLKEQTSYPPTHYIRRVPQRKVHYFTALQMLQLIILCAFGMYPLPYMKMVFPLLMILLVPVRTGLLPRLIDAKYLDIMD 682
BLAST of slc4a-4 vs. Ensembl Medaka
Match: slc4a3 (solute carrier family 4 member 3 [Source:NCBI gene;Acc:101164449]) HSP 1 Score: 198.364 bits (503), Expect = 2.848e-51 Identity = 177/674 (26.26%), Postives = 316/674 (46.88%), Query Frame = 2
Query: 1106 VYFVMLVITPKKEKDTKSDI---ELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQN----------------HARDLAE-----EQRLYRRRSIRITEVMNQAFAYEEK------------------------FPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIM-----SFIGSYLFKDIKIDTFKTRSEEE---FSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALD 2959
V F+ +++ P ++S++ E+ R+FATL+SD F FA D+ +++L +DL + ++++ R+R R + + E+ P G G++ D+R+R P+YISD+KD + + ++A F+YFA L P++ FG L + T+G + V +I+S G+ F+L GQPL+++ + PL ++ + Y Y + T W+G + +++ + S L+R+ + T+EIFA IS+ FI + + KVF K + V T +TT A G N N ++ LL L+L++GT ++ + F + FL R ++ D+ +P+++L+ S +Y K F S ++ F F + + A++ A + +L FM+ +TS +V+ +L KGS +H DLL++ I+ + LFGLPW+ S HV AL + + G + I +V+E R + ++ +++ L +P+AVL G+F+YM +T+L G QL ER+ L+ T +P Y+ +V K + + QL + AL + + FP +L++ +P+R I + + ALD
Sbjct: 576 VRFIFVLLGP-----SQSNVDYHEIGRSFATLMSDKNFHEVAYFA---DDRQDLLNGINKFLDCSIVIPPSDIEGKDLLKTVADFQKQILRKRREREGKKHHPMLGAEQDNKDVTPNEEEEEEDHEVDPLTRSGIPFG-GLIHDIRRRYPLYISDFKDALD-----MQCIAAVIFIYFAALSPTITFGGLLGEKTEGMMGVTELIVSTATLGVLFSLFAGQPLLIIGFSGPLLVFEEAYYKFCQAYKFEYLTGRVWIGFWLIGIVLVIVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFSKLFKVF-KEHPLMAVYPT----DTTAATGFPNEDNLIF------NQPNTALLSLVLMMGTFFIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVSVLVDYSITDTYTQKLNVPSGFSVTSPDKRGWFISPFGDKQPFPTWMMGASVVPALLVFILIFMETQITSLIVSKKERRLIKGSGFHLDLLLIVILGAICPLFGLPWLTAATVRSVTHVNALTVMSKATAPGEK--PMIQEVKEQR-LTGLLVAVLVGMSIVMTDVLRLIPLAVLFGIFLYMGVTSLTGIQLYERITLMVTPAKHHPDHIYVTKV---KTWRMNMFTIIQLTCIVALWVVKSTVVSLAFPFILIMTVPLRRLILSRIFEERELQALD 1218
BLAST of slc4a-4 vs. Planmine SMEST
Match: SMESG000039045.1 (SMESG000039045.1) HSP 1 Score: 1637.47 bits (4239), Expect = 0.000e+0 Identity = 868/868 (100.00%), Postives = 868/868 (100.00%), Query Frame = 2
Query: 365 MINSYSSNDKSVPKLVLTNCNQSPAIDRTNRRTISGLYNFKKQSTNNDDKDSKDRNLLLSPTNYINRQISETSEMSTDTVSNFSIGSLARYYRTADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 2968
MINSYSSNDKSVPKLVLTNCNQSPAIDRTNRRTISGLYNFKKQSTNNDDKDSKDRNLLLSPTNYINRQISETSEMSTDTVSNFSIGSLARYYRTADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNSIFLILYSLLDLSKLMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGLLFLLLLIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRLTGLISHILIGLSLLLLPIPLIYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHLFTVLQLTQLGLLCALGFAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI
Sbjct: 1 MINSYSSNDKSVPKLVLTNCNQSPAIDRTNRRTISGLYNFKKQSTNNDDKDSKDRNLLLSPTNYINRQISETSEMSTDTVSNFSIGSLARYYRTADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNSIFLILYSLLDLSKLMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGLLFLLLLIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRLTGLISHILIGLSLLLLPIPLIYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHLFTVLQLTQLGLLCALGFAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 868
BLAST of slc4a-4 vs. Planmine SMEST
Match: SMESG000039045.1 (SMESG000039045.1) HSP 1 Score: 1435.62 bits (3715), Expect = 0.000e+0 Identity = 772/781 (98.85%), Postives = 773/781 (98.98%), Query Frame = 2
Query: 626 LARYYRTADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 2968
L + Y GEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNSIFLILYSLLDLSKLMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGLLFLLLLIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRLTGLISHILIGLSLLLLPIPLIYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHLFTVLQLTQLGLLCALGFAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI
Sbjct: 57 LNKNYTPRTVKGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNSIFLILYSLLDLSKLMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGLLFLLLLIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRLTGLISHILIGLSLLLLPIPLIYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHLFTVLQLTQLGLLCALGFAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 837
BLAST of slc4a-4 vs. Planmine SMEST
Match: SMESG000009949.1 (SMESG000009949.1) HSP 1 Score: 868.611 bits (2243), Expect = 0.000e+0 Identity = 468/851 (54.99%), Postives = 638/851 (74.97%), Query Frame = 2
Query: 485 KKQSTNNDDKDSKDRNLLL---SPTNYINRQI--SETSEMSTDTVSNFSIGSLARYYRTADEN-GEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQ--MDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVN---------------KTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 2968
+++ T D++ S +L L SP ++RQ S S +S D +SN S +LA + ADE + +PCL L+RLEKIP+KDFS+EVRATLD++KFLKE VL+LDM + ++ I++ +L I LA +V+ + ++ + EAK LF+++ Y ++YQRLAKT++G+ ++E EGL TDQSW+ MCSL C+HKRHVAIARL PVN+GRSSEG+YF++LV+TP KEK TKSDIEL RTFAT+ +D+EFR QLLF+++ ++FKE+LQ H+ DL E+Q + RR+S+++ EVMNQAF +++K+ +G+GIV D +KR PVY+ D++DG +G GTIRK++SA FLYFACLLPS+AFGVL NT+GKI+V+RVI+SQ +GGLCF GQPLI++LTTAPL L++K+I +I Y L F+ M+S VG+ NS+ LILY++ D+SKLMRWSTRS+EEIFALF++I+F+VDAVKD+ K F Y + ++ + + + ++ L + ++ ++E +L+L L+ GTVWL I TKTPFLN++KR ++ D++LPLAV+IMS IG+YLFK+I++ F EE+ + ++ A+ A+ LAFPLSLL FMDQN++SAMVN P+NKLKKGS+YHWDLL+VA+IN LS+FGLP VHG LPHSPLHVKALADLEERID+ H +++TIVKVRETR+T ++SH+ IG+SL +LPIPLIY+P+AVLDGLFVYMA+T LYGNQ ER++LLFTEQ+AYPPSHYLRRVPQRK+H+FT LQ+ QL LC LGF+P+PY K+GFP+LLL M RH + P+ I Y++ALDKPI
Sbjct: 68 EQEVTIKDNRTSISSHLFLLPPSPGRRLSRQRQGSSASNVSVDNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTI--LANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQPLIILLTTAPLALFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTDHLRLSRFKRAFSGIISNISISLTQTNLNSSLYSSNSCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVI-VEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDKPI 915
BLAST of slc4a-4 vs. Planmine SMEST
Match: SMESG000061700.1 (SMESG000061700.1) HSP 1 Score: 847.04 bits (2187), Expect = 0.000e+0 Identity = 471/885 (53.22%), Postives = 627/885 (70.85%), Query Frame = 2
Query: 353 DHLNMINSYSSNDKSVPKLVLTNCNQSPAIDRTNRRTISGLYNFKKQSTNNDDKDSKDRNLLLSPTNYINRQISETSEMSTDTVSNFSIGSLARYYRTADENGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITT---------------EESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDK 2962
HL++ ++ S++ S +VL N N + T+RRT S L F NN D + ++L VS + +L+ +Y + P LVL+RLEK+P+KDFSSEVRA+LD+EKF+KE VL L+M ++ I+E +L I + I ++ +I EAK LFM + +SYQRLAKT+KGI I++ EGL+ DQSWI+AM +L +HKRH+AIARL TP NLGRS+E V+F++LV+ P KEK TKS+IEL RTF+T+++D++FR QLL + E +F+ MLQ AR LAE Q++ R+RS+++ EVM+QAF+ + KF +G GIV D+++RIP Y+SDY DG +G TIRK+ S +FLYF+CLLPS+AFGVL NTD KI+VKRVI+SQ +GGL F ++GGQPLIVMLTTAPL LY K+I+ IS +Y + F MF+ GIFN+++L++YSL D+ KLM+WST+STEE+FA F++IAF VDA KDV K F + Y NK VN ++ K L N +N F +T ++ +L+LLL IGTVWL + NFTKTP+LN+ KR L+AD++LPLA+ IMS IG+ LF+DI +D F E+ F + VN + A+ + L FPLSLLFFMDQN+ S+MVN PSNKLKKGS +HWDL IVA+IN LS+FGLPW+HG +PHSPLHVKAL+D+EERID GH++++TIV+VRETR+T ++S+I I LSL LLP PL Y+PIAVLDGLF++MA+T+LY NQ ER+ LLFTEQ+AYPPSHYLRRVPQRK+HLFT QL QL +L ALGF+P+PY K+GFPI+LLLQ+PIRH I PKFI +I+A+DK
Sbjct: 32 QHLSLSPNFLSHNTSHHSIVLENLN-----NVTDRRT-SNLSQF-----NNSDGYPDNISML-------------------SGVSGIGLRNLSLFYNSPP------PYLVLSRLEKLPLKDFSSEVRASLDIEKFVKESVLFLEMPCLSMEEIIERMLINILECEITDEIS-LEMWIKEAKTKLFMHTSFLTYSYQRLAKTIKGISIDDTEGLAMDQSWITAMATLPNLHKRHLAIARLSTPANLGRSNENVHFIILVLNPTKEKGTKSEIELGRTFSTIMADIDFRQQLLMIENEQDFRSMLQFQARQLAETQKILRKRSVKVDEVMDQAFSVKTKFWIGGGIVGDIKRRIPHYLSDYCDGFKGANTIRKVFSTTSFLYFSCLLPSIAFGVLNGNNTDRKIDVKRVIISQAIGGLVFGILGGQPLIVMLTTAPLALYTKIIFTISTEYKIDFSAMFACTGIFNAVYLMIYSLTDMCKLMKWSTKSTEEVFAFFVAIAFTVDASKDVYKEFAQHYQCAEENK----VNNSIFKSLSNMSNPFQITSTLSPMPDFHNSLHKGHSPCHRDVSVLYLLLTIGTVWLAGHLFNFTKTPYLNARKRELLADFALPLAITIMSIIGALLFRDINLDPF-YYDEKVFQFQPVNLPILGWKAILSCAALGFPLSLLFFMDQNIASSMVNSPSNKLKKGSTFHWDLFIVALINGFLSIFGLPWIHGAIPHSPLHVKALSDIEERIDIGHKVHQTIVRVRETRVTSILSNIFIALSLFLLPKPLSYIPIAVLDGLFIHMAVTSLYNNQFCERITLLFTEQSAYPPSHYLRRVPQRKLHLFTFFQLIQLIMLSALGFSPSPYMKMGFPIVLLLQIPIRHKIIPKFIDEIFINAMDK 874
BLAST of slc4a-4 vs. Planmine SMEST
Match: SMESG000012150.1 (SMESG000012150.1) HSP 1 Score: 548.125 bits (1411), Expect = 6.869e-179 Identity = 332/769 (43.17%), Postives = 475/769 (61.77%), Query Frame = 2
Query: 665 GLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQMDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLL-FAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNXXXXXXXXXXXXXXXMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLVNKTVPIVNTTLAKGLLNSTNEFITITTEESRKENGXXXXXXXIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRXXXXXXXXXXXXXXXXXXXXXXYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHXXXXXXXXXXXXXXXXXXAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 2968
G LV+ R + S E+RA D EKF ++L+ + IV+ LL++++ L ++D + A L + + + Y + AKT+ G + ++ D SW+ AM SL+ + R V P+N+G S V + +VI P KEK K DIE SR A ++SD EFR + + TE F++ + A L + +S + K LG GI D R R+P Y SDYKD +I K ++ L+F+ LLP++AFG+L + T+ KINV +L+Q +GG+ FAL GGQP+I+MLTT+PL+L I Y +++ F ++W+GIFN+++L +YS S +M++S RSTEE F LF+S+ F++D+VK K F+ Y VN T+A T KE LLF+LLL+ T+ LG++ T+TPFLNS R ++++++LP++VL MSFIGSY+FK++KI +F S+ + ++ I+ + A +AFPLS+LFFM+QN+ S++VNCP NKLKKG AYH+DLL+V IINL+LS+FGLPWVHG LPHSP+HV ALA +EE ID G++I + +VKV ETR+ +I++ILIG + L+P PL+Y+P VL+GLF+YMA TAL+ NQL ER++L TEQ+AYPP+HYL+RVPQ+KVH+FT +Q QL LLC LGF P Y K+ FP +L+LQ+P RH IFPK IS Y+DALDK I
Sbjct: 37 GFNELVITRNRPTNVPFLSEEIRARADAEKFSSTSSIVLNNYHIKTEIIVKDLLQKMF-LTTIRDHDKLDLSVELAFAELIVSNNDKEGDYFQFAKTINGFEHGKGGIMTADPSWLIAMASLSWIDHRLVGFTTTVHPINMGPSHSSVQMLAIVIAPIKEKTMKRDIETSRNIAAIMSDPEFRQTIRGYDVTETTFRDAFKETALRLQNS----KPKSDNSEGEHEEHSGLHNKVSLGRGIYKDFRGRLPHYWSDYKDAFMDKNSIFKTITTIFVLFFSNLLPTIAFGMLNEYGTNHKINVASGLLAQLIGGVGFALFGGQPMIIMLTTSPLSLLIAAFYTMNSSLGYKFLQFYTWIGIFNAVYLFVYSFTGFSMIMKFSRRSTEETFELFVSVTFVIDSVKACTKSFHNYYYGGHC------VNATIA-------------VTGSCTKEESLLFVLLLLSTMALGLWLNGLTETPFLNSMSRKMLSEFALPVSVLFMSFIGSYVFKEVKIHSFTAPPWRNISMIATDIRELPIAGIMLAAAVAFPLSILFFMEQNIASSIVNCPLNKLKKGPAYHYDLLVVGIINLILSIFGLPWVHGALPHSPMHVTALATIEEHIDEGNKIDQKVVKVTETRIPVIIANILIGCCIFLMPYPLLYIPAPVLNGLFLYMAFTALHSNQLFERLLLFITEQSAYPPNHYLKRVPQKKVHIFTSIQFLQLLLLCILGFTPITYVKLVFPFILILQLPFRHIIFPKIISKKYLDALDKLI 781 The following BLAST results are available for this feature:
BLAST of slc4a-4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of slc4a-4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of slc4a-4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of slc4a-4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of slc4a-4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of slc4a-4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of slc4a-4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of slc4a-4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of slc4a-4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of slc4a-4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of slc4a-4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of slc4a-4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of slc4a-4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of slc4a-4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30003166 ID=SMED30003166|Name=slc4a-4|organism=Schmidtea mediterranea sexual|type=transcript|length=3234bpback to top protein sequence of SMED30003166-orf-1 >SMED30003166-orf-1 ID=SMED30003166-orf-1|Name=SMED30003166-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=892bp MNNLMPTQNSLNRRNSRSVDHLNMINSYSSNDKSVPKLVLTNCNQSPAIDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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