SMED30003142
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30003142 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Alignments
SMED30003142 aligns in the following genomic locations:
Homology
BLAST of SMED30003142 vs. Ensembl Human
Match: TMX3 (thioredoxin related transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:24718]) HSP 1 Score: 172.555 bits (436), Expect = 9.316e-47 Identity = 120/425 (28.24%), Postives = 206/425 (48.47%), Query Frame = -1 Query: 397 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESST--MKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADNRRIEAR 1659 V +L+ +F E + WLV FYAPWCG+C+KLEPI+NE+ +K + P+K+ ++DAT Y +AS + +RGYPTIK + G Y + G RT + +I F+ R G ++ LPS+ F + H FF+Y+G S LK Y D A+ L + +YF+S + +P+ Y L E +LV+K + + E + L +WI+ RF + + L+ + + E+ +S +L S +++A + + D F +N L M L VP V++ N ++ +++K +++ + F+++ G +E GG +++R +D + ++ ++P++ F+ G+PL VIS +CY I T+D D IE R Sbjct: 28 VEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRH--RVFFVYVGGESP-LKEKYIDAASELIVYTYFFSASEEVVPE--YVTL--------KEMPAVLVFKDETYFVYDEYE-----DGDLSSWINRERFQNYLAMDGFLLY---------------ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLLMDELTVPTVVVLNTSNQQYFLLD-----RQIKNVED--MVQFINNILDGTVEAQGGDSILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIY---TADTDGGYIEER 409
BLAST of SMED30003142 vs. Ensembl Human
Match: TMX3 (thioredoxin related transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:24718]) HSP 1 Score: 133.265 bits (334), Expect = 3.014e-35 Identity = 67/166 (40.36%), Postives = 102/166 (61.45%), Query Frame = -1 Query: 1168 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQ 1659 V +L+ +F E + WLV FYAPWCG+C+KLEPI+NE+ +K + P+K+ ++DAT Y +AS + +RGYPTIK + G Y + G RT + +I F+ R G ++ LPS+ F + H FF+Y+G S LK Y D A+ L + +YF+S + +P+ Sbjct: 28 VEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRH--RVFFVYVGGESP-LKEKYIDAASELIVYTYFFSASEEVVPE 190
BLAST of SMED30003142 vs. Ensembl Human
Match: TMX3 (thioredoxin related transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:24718]) HSP 1 Score: 103.219 bits (256), Expect = 1.508e-24 Identity = 58/166 (34.94%), Postives = 88/166 (53.01%), Query Frame = -1 Query: 1168 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQ 1659 V +L+ +F E + WLV FYAPWCG+C+KLEPI+NE+ +K + P+K+ ++DAT Y +AS + +RGYPTIK ++ LPS+ F + H FF+Y+G S LK Y D A+ L + +YF+S + +P+ Sbjct: 28 VEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL---------------------------ALIRPLPSQQMFEHMQKRH--RVFFVYVGGESP-LKEKYIDAASELIVYTYFFSASEEVVPE 163
BLAST of SMED30003142 vs. Ensembl Human
Match: TMX3 (thioredoxin related transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:24718]) HSP 1 Score: 85.8853 bits (211), Expect = 2.462e-19 Identity = 38/76 (50.00%), Postives = 55/76 (72.37%), Query Frame = -1 Query: 1438 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIK 1659 V +L+ +F E + WLV FYAPWCG+C+KLEPI+NE+ +K + P+K+ ++DAT Y +AS + +RGYPTIK Sbjct: 28 VEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIK 103
BLAST of SMED30003142 vs. Ensembl Human
Match: P4HB (prolyl 4-hydroxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8548]) HSP 1 Score: 82.0333 bits (201), Expect = 8.084e-16 Identity = 71/233 (30.47%), Postives = 111/233 (47.64%), Query Frame = -1 Query: 991 NSNFIE-IADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIK--DLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYT---HDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRF--------STFPKI 1647 SNF E +A LV+FYAPWCG+C+ L P Y + +K I++A++DAT D+A Y +RGYPTIK+ D + + R + ++ + K+ GPA LP A ES + + IG + K V D A + +I++ IP S+ D+ S ++G +L K D + +F+ E++ N L ++I N+ T PKI Sbjct: 31 KSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGA----AAESLVESSEVAVIG----FFKDVESDSAKQFLQAA--EAIDD--IPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRN-NFEGEVTKEN--LLDFIKHNQLPLVIEFTEQTAPKI 248 HSP 2 Score: 55.4546 bits (132), Expect = 2.009e-7 Identity = 31/99 (31.31%), Postives = 58/99 (58.59%), Query Frame = -1 Query: 1372 LNSNFIEIA--DKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLP-IKIARIDATRYPDVASFYQIRGYPTIKYINGT---DIYTHDGDRTVEHLILF 1650 + NF ++A +K V+FYAPWCG+C++L PI+++L KD I IA++D+T + ++ +PT+K+ + + ++G+RT++ F Sbjct: 373 VGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDST--ANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKF 469
BLAST of SMED30003142 vs. Ensembl Celegans
Match: ZK973.11 (pep chromosome:WBcel235:I:4379325:4381948:-1 gene:WBGene00022836.1 transcript:ZK973.11.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK973.11) HSP 1 Score: 135.191 bits (339), Expect = 5.633e-34 Identity = 101/422 (23.93%), Postives = 201/422 (47.63%), Query Frame = -1 Query: 418 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKD--LPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFN---DEQNDLFFVW--STDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMD-TSDAD 1659 V++L+ F+++ D+G W V+FYAPWC +C++L P+++++ + D LPI++ ++D TR+P VA+ I+GYPTI + + + G R E L+ F+KR P ++ + +E + + S + +++ G S L +++ A+S + FYS+ S+ + V+K + ++ F+ E L W++ R+ F + + +L E+ K +++++ + S +S ++ F + A + D N F W +D+AS + M + P++ IF ++ Y+ D + +K+I F+ I +GG +++R ++ + + +T P+L+ + GVP++ +S +CY+IC D T D D Sbjct: 30 VLDLSDKFLDVKDEGMWFVEFYAPWCAHCKRLHPVWDQVGHTLSDSNLPIRVGKLDCTRFPAVANKLSIQGYPTILFFRNGHVIDYRGGREKEALVSFAKRCAAPIIEVI-NENQIEKVKLSARSQPSYVFFGTSSGPLFDAFNEAASSKFSVARFYSVAPPENDASFRQR--------------VAVFKDNFEIEFNGDIE------KLTEWVTRERWPGFLQATSSNLAEIGASGKLVVLVVSSESHKF-----------NNTSPIREFHKTAEEASKELRKHPDLWNRFQFAWLDGSDLASQ--IQMAAVSEPHLFIFNYTSYEYYLSEDEPSQMTIKSI-LTFLEQTSEGIDKETIVAFGGRHLLTRIKRMAFELYWNIAQMFATQPLLSSCLFGVPIAFLSIICYSICSADFTVDRD 416
BLAST of SMED30003142 vs. Ensembl Celegans
Match: pdi-2 (Protein disulfide-isomerase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q17770]) HSP 1 Score: 85.8853 bits (211), Expect = 1.757e-17 Identity = 65/231 (28.14%), Postives = 109/231 (47.19%), Query Frame = -1 Query: 982 NVIELNS-NFIEIADKGPW-LVKFYAPWCGYCRKLEPIYNELEAHIKDLP--IKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQH 1662 NVI L NF E+ + + LV+FYAPWCG+C+ L P Y + +K+ IK+ ++DAT + +V+S +++RGYPT+K ++G R + +I + K+ GP K L E ES + Y D +S + ++A + + S E+ + S ++L G +L K D F E+++ L+ WI NR + + +Q Sbjct: 24 NVIVLTKDNFDEVINGNEFILVEFYAPWCGHCKSLAPEYAKAATQLKEEGSDIKLGKLDATVHGEVSSKFEVRGYPTLKLFRNGKPQEYNGGRDHDSIIAWLKKKTGPVAKPLADADAVKELQESADV-VVIGYFKDTTSDDAKTFLEVAAGIDDVPFGISTED-----AVKSEIELKGE------GIVLFKKFDDG-RVAFDEKLT--QDGLKTWIQANRLALVSEFTQE 239 HSP 2 Score: 61.6178 bits (148), Expect = 1.054e-9 Identity = 33/84 (39.29%), Postives = 50/84 (59.52%), Query Frame = -1 Query: 1372 LVKFYAPWCGYCRKLEPIYNEL-EAHIKDLPIKIARIDAT--RYPDVASFYQIRGYPTIKYI--NGTDIYTHDGDRTVEHLILF 1608 LV+FYAPWCG+C++L P +++L E D I IA++D+T DV +I+ +PTIK+ + + GDRT+E F Sbjct: 385 LVEFYAPWCGHCKQLAPTWDKLGEKFADDESIVIAKMDSTLNEVEDV----KIQSFPTIKFFPAGSNKVVDYTGDRTIEGFTKF 464
BLAST of SMED30003142 vs. Ensembl Celegans
Match: pdi-2 (Protein disulfide-isomerase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q17770]) HSP 1 Score: 85.8853 bits (211), Expect = 1.757e-17 Identity = 65/231 (28.14%), Postives = 109/231 (47.19%), Query Frame = -1 Query: 982 NVIELNS-NFIEIADKGPW-LVKFYAPWCGYCRKLEPIYNELEAHIKDLP--IKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQH 1662 NVI L NF E+ + + LV+FYAPWCG+C+ L P Y + +K+ IK+ ++DAT + +V+S +++RGYPT+K ++G R + +I + K+ GP K L E ES + Y D +S + ++A + + S E+ + S ++L G +L K D F E+++ L+ WI NR + + +Q Sbjct: 24 NVIVLTKDNFDEVINGNEFILVEFYAPWCGHCKSLAPEYAKAATQLKEEGSDIKLGKLDATVHGEVSSKFEVRGYPTLKLFRNGKPQEYNGGRDHDSIIAWLKKKTGPVAKPLADADAVKELQESADV-VVIGYFKDTTSDDAKTFLEVAAGIDDVPFGISTED-----AVKSEIELKGE------GIVLFKKFDDG-RVAFDEKLT--QDGLKTWIQANRLALVSEFTQE 239 HSP 2 Score: 61.6178 bits (148), Expect = 1.054e-9 Identity = 33/84 (39.29%), Postives = 50/84 (59.52%), Query Frame = -1 Query: 1372 LVKFYAPWCGYCRKLEPIYNEL-EAHIKDLPIKIARIDAT--RYPDVASFYQIRGYPTIKYI--NGTDIYTHDGDRTVEHLILF 1608 LV+FYAPWCG+C++L P +++L E D I IA++D+T DV +I+ +PTIK+ + + GDRT+E F Sbjct: 385 LVEFYAPWCGHCKQLAPTWDKLGEKFADDESIVIAKMDSTLNEVEDV----KIQSFPTIKFFPAGSNKVVDYTGDRTIEGFTKF 464
BLAST of SMED30003142 vs. Ensembl Celegans
Match: pdi-1 (Protein disulfide-isomerase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q17967]) HSP 1 Score: 85.8853 bits (211), Expect = 2.043e-17 Identity = 51/153 (33.33%), Postives = 81/153 (52.94%), Query Frame = -1 Query: 1216 NVIELN-SNFIEIADKGPW-LVKFYAPWCGYCRKLEPIYNELEAHIKDLP--IKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSL 1662 NV+ L SNF E + + LVKFYAPWC +C+ L P Y+E +K+ IK+A++DAT +AS +++RGYPTI Y + G R ++ + K+ GP V + S + E ++ Y D S +Y+++A+S+ Sbjct: 24 NVLVLTESNFEETINGNEFVLVKFYAPWCVHCKSLAPKYDEAADLLKEEGSDIKLAKVDATENQALASKFEVRGYPTILYFKSGKPTKYTGGRATAQIVDWVKKKSGPTVTTVESVEQLEE-LKGKTRVVVLGYFKDAKSDAATIYNEVADSV 175 HSP 2 Score: 63.1586 bits (152), Expect = 2.879e-10 Identity = 39/108 (36.11%), Postives = 59/108 (54.63%), Query Frame = -1 Query: 1348 LNSNFIEIA--DKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLP-IKIARIDAT--RYPDVASFYQIRGYPTIKY--INGTDIYTHDGDRTVEHLILFSKRALGPA 1650 + SNF EIA + VKFYAPWCG+C++L P+++EL + P + IA++DAT DV ++ +PT+K + +DGDR +E F + G A Sbjct: 369 VASNFNEIALDETKTVFVKFYAPWCGHCKQLVPVWDELAEKYESNPNVVIAKLDATLNELADV----KVNSFPTLKLWPAGSSTPVDYDGDRNLEKFEEFVNKYAGSA 472
BLAST of SMED30003142 vs. Ensembl Celegans
Match: pdi-1 (Protein disulfide-isomerase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q17967]) HSP 1 Score: 85.8853 bits (211), Expect = 2.043e-17 Identity = 51/153 (33.33%), Postives = 81/153 (52.94%), Query Frame = -1 Query: 1216 NVIELN-SNFIEIADKGPW-LVKFYAPWCGYCRKLEPIYNELEAHIKDLP--IKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSL 1662 NV+ L SNF E + + LVKFYAPWC +C+ L P Y+E +K+ IK+A++DAT +AS +++RGYPTI Y + G R ++ + K+ GP V + S + E ++ Y D S +Y+++A+S+ Sbjct: 24 NVLVLTESNFEETINGNEFVLVKFYAPWCVHCKSLAPKYDEAADLLKEEGSDIKLAKVDATENQALASKFEVRGYPTILYFKSGKPTKYTGGRATAQIVDWVKKKSGPTVTTVESVEQLEE-LKGKTRVVVLGYFKDAKSDAATIYNEVADSV 175 HSP 2 Score: 63.1586 bits (152), Expect = 2.879e-10 Identity = 39/108 (36.11%), Postives = 59/108 (54.63%), Query Frame = -1 Query: 1348 LNSNFIEIA--DKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLP-IKIARIDAT--RYPDVASFYQIRGYPTIKY--INGTDIYTHDGDRTVEHLILFSKRALGPA 1650 + SNF EIA + VKFYAPWCG+C++L P+++EL + P + IA++DAT DV ++ +PT+K + +DGDR +E F + G A Sbjct: 369 VASNFNEIALDETKTVFVKFYAPWCGHCKQLVPVWDELAEKYESNPNVVIAKLDATLNELADV----KVNSFPTLKLWPAGSSTPVDYDGDRNLEKFEEFVNKYAGSA 472
BLAST of SMED30003142 vs. Ensembl Fly
Match: CG5027 (gene:FBgn0036579 transcript:FBtr0075457) HSP 1 Score: 149.058 bits (375), Expect = 7.887e-39 Identity = 105/431 (24.36%), Postives = 200/431 (46.40%), Query Frame = -1 Query: 385 NVIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSF---HFKEEI--SSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADNRRIEARQQKK 1662 V+EL+ FI++ +G WLV FYAPWCGYC+K EPI+ + + +++ R+D T+YP A +++RGYPTI +I G +T++GDR + L+ ++ R GP V+ + SH + FF+++G + + Y A + +FY+ Q H D + ++V+K ++ + H E+ + +N ++ W++ RF+ FPK+++ ++ + +++ + N E E M K A ++D+ F W + + + + + L P+++ +I P+ + Q + + +H FL S ++ YGG + ++ RA ++ L + P+L I G+PL +S + Y+I C D + E ++K+ Sbjct: 27 KVLELSDRFIDVRHEGQWLVMFYAPWCGYCKKTEPIFALVAQALHATNVRVGRLDCTKYPAAAKEFKVRGYPTIMFIKGNMEFTYNGDRGRDELVDYALRMSGPPVQLVTRTESVDMLKGSHTI--FFIFVGQQEGVVWDTYYAAAEGYQEHGFFYATSEDIAAQ----HFDFEKLPA------VIVYKEEQHHFYPHGHLAHEMDPNEVNETVFQWVNVERFTLFPKVTRFNI-----HQLLKTNKYLVLAVVQEDKLNQIATHELEFRDMVEGVIRKHRA--RYHDK---FQFGWIGEPSIAHSIILDQLPTPHLIAINSSTQHHFI-PEDDPMQ----MTPQALHLFLESIRNESAIAYGGDTYFVRLNRALFEVRRALRDMWLGNPVLTTVIFGLPLGFLSLIMYSIFCGDCLVTEEDPDEDHEKKE 430
BLAST of SMED30003142 vs. Ensembl Fly
Match: Pdi (gene:FBgn0286818 transcript:FBtr0346644) HSP 1 Score: 87.4261 bits (215), Expect = 8.972e-18 Identity = 62/217 (28.57%), Postives = 102/217 (47.00%), Query Frame = -1 Query: 991 IADKGPWLVKFYAPWCGYCRKLEPIYNELEAHI--KDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKP--DRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKI 1629 IAD LV+FYAPWCG+C+ L P Y + + K+ PIK+A++DAT ++A Y +RGYPT+K+ + G R +I + + GP K L S + ++ + + + D S + +AN+ L S+ + + S+ D+ + +NG +L +KP D+K F LN +N F + + P I Sbjct: 41 IADNEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGSPVEYSGGRQAADIIAWVTKKTGPPAKDLTSVADAEQFLKDNEI-AIIGFFKDLESEEAKTFTKVANA--LDSFVFGVS---------SNADVIAKYEAKDNGVVL-FKPFDDKKSVFE-----GELNE--ENLKKFAQVQSLPLI 237 HSP 2 Score: 64.3142 bits (155), Expect = 1.750e-10 Identity = 39/98 (39.80%), Postives = 59/98 (60.20%), Query Frame = -1 Query: 1372 LNSNFIEIA-DKGP-WLVKFYAPWCGYCRKLEPIYNELEAHIKD-LPIKIARIDATRYPDVASFYQIRGYPTIKYINGTD--IYTHDGDRTVEHLILF 1650 ++SNF +A DK LV+FYAPWCG+C++L PIY++L KD I IA++D+T + +I +PTIKY D + + DRT++ + F Sbjct: 373 VSSNFESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNEDIVIAKMDST--ANELESIKISSFPTIKYFRKEDNKVIDFNLDRTLDDFVKF 468
BLAST of SMED30003142 vs. Ensembl Fly
Match: Pdi (gene:FBgn0286818 transcript:FBtr0075648) HSP 1 Score: 87.4261 bits (215), Expect = 8.972e-18 Identity = 62/217 (28.57%), Postives = 102/217 (47.00%), Query Frame = -1 Query: 991 IADKGPWLVKFYAPWCGYCRKLEPIYNELEAHI--KDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKP--DRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKI 1629 IAD LV+FYAPWCG+C+ L P Y + + K+ PIK+A++DAT ++A Y +RGYPT+K+ + G R +I + + GP K L S + ++ + + + D S + +AN+ L S+ + + S+ D+ + +NG +L +KP D+K F LN +N F + + P I Sbjct: 41 IADNEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGSPVEYSGGRQAADIIAWVTKKTGPPAKDLTSVADAEQFLKDNEI-AIIGFFKDLESEEAKTFTKVANA--LDSFVFGVS---------SNADVIAKYEAKDNGVVL-FKPFDDKKSVFE-----GELNE--ENLKKFAQVQSLPLI 237 HSP 2 Score: 64.3142 bits (155), Expect = 1.750e-10 Identity = 39/98 (39.80%), Postives = 59/98 (60.20%), Query Frame = -1 Query: 1372 LNSNFIEIA-DKGP-WLVKFYAPWCGYCRKLEPIYNELEAHIKD-LPIKIARIDATRYPDVASFYQIRGYPTIKYINGTD--IYTHDGDRTVEHLILF 1650 ++SNF +A DK LV+FYAPWCG+C++L PIY++L KD I IA++D+T + +I +PTIKY D + + DRT++ + F Sbjct: 373 VSSNFESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNEDIVIAKMDST--ANELESIKISSFPTIKYFRKEDNKVIDFNLDRTLDDFVKF 468
BLAST of SMED30003142 vs. Ensembl Fly
Match: ERp60 (gene:FBgn0033663 transcript:FBtr0088058) HSP 1 Score: 76.2554 bits (186), Expect = 2.707e-14 Identity = 43/141 (30.50%), Postives = 73/141 (51.77%), Query Frame = -1 Query: 1198 LVKFYAPWCGYCRKLEPIYNELEAHIK--DLPIKIARIDATRY-PDVASFYQIRGYPTIKYINGTDI-YTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYF 1608 LV FYAPWCG+C++L+P Y + +K D PIK+A++D T + S Y + GYPT+K ++ ++G R + + + +GPA K + + + +++ T F Y D S L ++ A+ R + F Sbjct: 43 LVMFYAPWCGHCKRLKPEYAKAAEIVKDDDPPIKLAKVDCTEAGKETCSKYSVSGYPTLKIFRQDEVSQDYNGPREASGIAKYMRAQVGPASKTVRTVAELKKFLDTKDT-TLFGYFSDSDSKLAKIFLKFADKNREKYRF 182 HSP 2 Score: 67.781 bits (164), Expect = 1.308e-11 Identity = 32/99 (32.32%), Postives = 56/99 (56.57%), Query Frame = -1 Query: 1321 LVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYI---NGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGR 1608 L++FYAPWCG+C+KL PIY EL ++D + I ++DAT DV + +RG+PT+ ++ +++G R V+ + + + +K G+ Sbjct: 386 LIEFYAPWCGHCKKLSPIYEELAEKLQDEDVAIVKMDATAN-DVPPEFNVRGFPTLFWLPKDAKNKPVSYNGGREVDDFLKYIAKEATTELKGFDRSGK 483
BLAST of SMED30003142 vs. Ensembl Fly
Match: CG9302 (gene:FBgn0032514 transcript:FBtr0080470) HSP 1 Score: 73.9442 bits (180), Expect = 1.543e-13 Identity = 37/101 (36.63%), Postives = 61/101 (60.40%), Query Frame = -1 Query: 1381 VIELNSNFIEIA--DKGPWLVKFYAPWCGYCRKLEPIYNE--LEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYI-NGT---DIYTHDGDRTVEHL 1659 ++ L S E A D+ LV FYAPWCG+C++++P Y + LE K +P +A +DAT+ P +A Y+++GYPT+K+ NG ++ + + VE + Sbjct: 273 IVHLTSQGFEPALKDEKSALVMFYAPWCGHCKRMKPEYEKAALEMKQKKIPGLLAALDATKEPSIAEKYKVKGYPTVKFFSNGVFKFEVNVREASKIVEFM 373 HSP 2 Score: 59.3066 bits (142), Expect = 7.200e-9 Identity = 29/81 (35.80%), Postives = 44/81 (54.32%), Query Frame = -1 Query: 1372 LVKFYAPWCGYCRKLEPIYNELEAHIKDLP-IKIARIDATRYPDVASFYQIRGYPTIKYINGTDI-YTHDGDRTVEHLILF 1608 LV FYAPWCG+C+ +P + ++D P I ID T+ + + Y +RGYPTI Y + ++G RT + I + Sbjct: 417 LVMFYAPWCGHCKHTKPEFTAAATALQDDPRIAFVAIDCTKLAALCAKYNVRGYPTILYFSYLKTKLDYNGGRTSKDFIAY 497 HSP 3 Score: 57.3806 bits (137), Expect = 2.719e-8 Identity = 34/101 (33.66%), Postives = 52/101 (51.49%), Query Frame = -1 Query: 1333 DKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKI-ARIDATRYPD--VASFYQIRGYPTIKYI-NGTDIYTHDGDRTVEHLILFSKRALGPAVKHLP 1623 D P LV FY PWCG+C+K++P Y + +K I A ++ R + + + I G+PT+ Y NG +T++G+ E L+ F L P K P Sbjct: 161 DIRPMLVMFYVPWCGFCKKMKPEYGKASTELKTKGGYILAAMNVERQENAPIRKMFNITGFPTLIYFENGKLRFTYEGENNKEALVSF---MLNPNAKPTP 258
BLAST of SMED30003142 vs. Ensembl Zebrafish
Match: tmx3a (thioredoxin related transmembrane protein 3a [Source:ZFIN;Acc:ZDB-GENE-050522-396]) HSP 1 Score: 136.346 bits (342), Expect = 3.142e-34 Identity = 112/422 (26.54%), Postives = 198/422 (46.92%), Query Frame = -1 Query: 400 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADNRRIEA 1659 V EL+ F E WLV+FYAPWC YC EP++ E+ A +K L P+ + +ID T + +A+ + IRGYPTIK G + + G RT + +I F+ R GP V+ L S F + H + F+YIG S LK Y A + +YF++ + +P++ L +++ ++GT ++ ++ L +WI+ RF ++ +I + L+++ L K + + + + S+ + ER S+ + + ++D F + +N L M L +P++++ YI P+S+ + I++ + FL+S G GG GF +R Y ++ V T P+ + F++G+P+ V+ + YA C +D + EA Sbjct: 24 VEELDDKFTEFRQNELWLVEFYAPWCAYCHTFEPVWTEVGAELKSLGSPVNVGKIDTTAHTSIATEFNIRGYPTIKLFKGDLSFDYKGPRTKDGIIEFTNRVSGPVVRPLSSVQLFQHVMSRH--DVIFVYIGGE-SLLKKEYYKAATEFIVHTYFFTASEEILPKAV--TLQDVPAVAVFKDGTYYIYN-------------EFIDGDLSSWINRERFLSYFQIDSYSLYQMGELSKLVALAVVDEKNPSEESIRYKTLMERVSTEYR-------------DHYKSDFQFGYVDGNEYVNGLIMGELAMPSIIVLNMSIDGYYI-PESST----ETIED--LLQFLNSVLDGSTTLLGGNGFWQCAKRIFYKGKNTVMSMVETAPVFSCFVLGLPVGVVVLVIYATCTAVPADDEKPEEEA 407
BLAST of SMED30003142 vs. Ensembl Zebrafish
Match: tmx3a (thioredoxin related transmembrane protein 3a [Source:ZFIN;Acc:ZDB-GENE-050522-396]) HSP 1 Score: 136.346 bits (342), Expect = 3.538e-34 Identity = 114/422 (27.01%), Postives = 199/422 (47.16%), Query Frame = -1 Query: 400 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADNRRIEA 1659 V EL+ F E WLV+FYAPWC YC EP++ E+ A +K L P+ + +ID T + +A+ + IRGYPTIK G + + G RT + +I F+ R GP V+ L S F + H + F+YIG S LK Y A + +YF++ + +P++ +L D + V+K +++ E ++ L +WI+ RF ++ +I + L+++ L K + + + + S+ + ER S+ + + ++D F + +N L M L +P++++ YI P+S+ + I++ + FL+S G GG GF +R Y ++ V T P+ + F++G+P+ V+ + YA C +D + EA Sbjct: 23 VEELDDKFTEFRQNELWLVEFYAPWCAYCHTFEPVWTEVGAELKSLGSPVNVGKIDTTAHTSIATEFNIRGYPTIKLFKGDLSFDYKGPRTKDGIIEFTNRVSGPVVRPLSSVQLFQHVMSRH--DVIFVYIGGE-SLLKKEYYKAATEFIVHTYFFTASEEILPKAV--------TLQDVP--AVAVFKDG---TYYIYNEF--IDGDLSSWINRERFLSYFQIDSYSLYQMGELSKLVALAVVDEKNPSEESIRYKTLMERVSTEYR-------------DHYKSDFQFGYVDGNEYVNGLIMGELAMPSIIVLNMSIDGYYI-PESST----ETIED--LLQFLNSVLDGSTTLLGGNGFWQCAKRIFYKGKNTVMSMVETAPVFSCFVLGLPVGVVVLVIYATCTAVPADDEKPEEEA 406
BLAST of SMED30003142 vs. Ensembl Zebrafish
Match: tmx3a (thioredoxin related transmembrane protein 3a [Source:ZFIN;Acc:ZDB-GENE-050522-396]) HSP 1 Score: 110.153 bits (274), Expect = 1.141e-27 Identity = 54/136 (39.71%), Postives = 76/136 (55.88%), Query Frame = -1 Query: 1258 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRS 1659 V EL+ F E WLV+FYAPWC YC EP++ E+ A +K L P+ + +ID T + +A+ + IRGYPTIK G + + G RT + +I F+ R GP V+ L S F + H + F+YIG S Sbjct: 23 VEELDDKFTEFRQNELWLVEFYAPWCAYCHTFEPVWTEVGAELKSLGSPVNVGKIDTTAHTSIATEFNIRGYPTIKLFKGDLSFDYKGPRTKDGIIEFTNRVSGPVVRPLSSVQLFQHVMSRH--DVIFVYIGGES 156
BLAST of SMED30003142 vs. Ensembl Zebrafish
Match: tmx3b (thioredoxin related transmembrane protein 3b [Source:ZFIN;Acc:ZDB-GENE-060901-5]) HSP 1 Score: 81.2629 bits (199), Expect = 2.512e-18 Identity = 32/60 (53.33%), Postives = 45/60 (75.00%), Query Frame = -1 Query: 1438 WLVKFYAPWCGYCRKLEPIYNELEAHI--KDLPIKIARIDATRYPDVASFYQIRGYPTIK 1611 WLV FYAPWCGYC+KLEP++ E+ A + P+++ ++DAT Y +AS + +RGYPTIK Sbjct: 37 WLVDFYAPWCGYCKKLEPVWEEVGAELSRSGSPVRVGKMDATAYSGMASEFGVRGYPTIK 96
BLAST of SMED30003142 vs. Ensembl Zebrafish
Match: pdia3 (protein disulfide isomerase family A, member 3 [Source:ZFIN;Acc:ZDB-GENE-031002-9]) HSP 1 Score: 83.1889 bits (204), Expect = 2.250e-16 Identity = 42/133 (31.58%), Postives = 70/133 (52.63%), Query Frame = -1 Query: 1213 LVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIK-YINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLR 1608 LV+F+APWCG+C++L P Y +K + + +A++D T V Y + GYPT+K + +G D +DG RT + ++ K+ GPA L +E F + YIGDR + + + D ++ + Sbjct: 4 LVEFFAPWCGHCKRLAPEYEAAATRLKGI-VPLAKVDCTANSKVCGKYGVSGYPTLKIFRDGEDSGGYDGPRTADGIVSHLKKQAGPASVELKNEADFEK------------YIGDRDASVVGFFADGGSAAQ 123 HSP 2 Score: 66.6254 bits (161), Expect = 3.921e-11 Identity = 36/86 (41.86%), Postives = 52/86 (60.47%), Query Frame = -1 Query: 1363 LVKFYAPWCGYCRKLEPIYNELEAHIKDLP-IKIARIDATRYPDVASFYQIRGYPTIKYINGT---DIYTHDGDRTVEHLILFSKR 1608 L++FYAPWCG+C+ LEP Y EL + + P I IA++DAT DV S Y++ G+PTI + + ++G R V I + KR Sbjct: 353 LIEFYAPWCGHCKSLEPKYKELGEKLSEDPNIVIAKMDATAN-DVPSPYEVSGFPTIYFSPAGRKQNPKKYEGGREVSDFISYLKR 437
BLAST of SMED30003142 vs. Ensembl Xenopus
Match: nup35 (nucleoporin 35kDa [Source:Xenbase;Acc:XB-GENE-980941]) HSP 1 Score: 172.94 bits (437), Expect = 8.653e-47 Identity = 117/417 (28.06%), Postives = 198/417 (47.48%), Query Frame = -1 Query: 421 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNE--LEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESST--MKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDA 1659 V +L+ +F E WLV FYAPWCG+C+KLEP++NE +E PI++ ++DAT + +AS + +RG+PTIK + G Y + G RT E ++ F+ R GP ++ LPS+ F + H F+Y+G S+ LK Y ++A+ L + +YF+S +P+ ++ LN E +LV+K + E + L +W++ RF + I L+ + + E+ +S +L S A+ +A + D F +N L M L +P ++ N ++ ++++ +E F++S G E GG G +++R YD + ++ ++P+L F+ G+PL VIS +CY IC DT D Sbjct: 46 VEDLDDSFKENRKDDIWLVDFYAPWCGHCKKLEPVWNEVGIEMRSSGSPIRVGKMDATVHSSIASEFGVRGFPTIKVLKGDMAYNYRGPRTKEDIVEFANRVAGPLIRPLPSQQMFDHVQKRH--SVLFVYVGVEST-LKEKYIEVASELIVYTYFFSSSEDVLPK----YVTLN------EVPAVLVFKDSTYFVYDEYE-----DGDLSSWVNKERFEGYLHIDGFTLY---------------ELGDTGKLVAVAVIDEKNNSVEHTRLKSIAQDVAKNYRDHFHRDFQFGHMDGNDYINSLLMDELSIPTFVVLNTSNQQYFLPS-----KQIENTEEMI--QFINSILDGTAEAQGGDGILQRIKRVFYDAKSTVVSVFKSSPLLGCFLFGLPLGVISIMCYGICTADTEDG 422
BLAST of SMED30003142 vs. Ensembl Xenopus
Match: nup35 (nucleoporin 35kDa [Source:Xenbase;Acc:XB-GENE-980941]) HSP 1 Score: 168.703 bits (426), Expect = 2.185e-45 Identity = 118/416 (28.37%), Postives = 198/416 (47.60%), Query Frame = -1 Query: 421 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNE--LEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDE-QNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDA 1659 V +L+ +F E WLV FYAPWCG+C+KLEP++NE +E PI++ ++DAT + +AS + +RG+PTIK + G Y + G RT E ++ F+ R GP ++ LPS+ F + H F+Y+G S+ LK Y ++A+ L + +YF+S +P+ ++ LN E +LV+K + E + L +W++ RF + I L+EL + I+I + F+ K +++ D D F +N L M L +P ++ N ++ ++++ +E F++S G E GG G +++R YD + ++ ++P+L F+ G+PL VIS +CY IC DT D Sbjct: 28 VEDLDDSFKENRKDDIWLVDFYAPWCGHCKKLEPVWNEVGIEMRSSGSPIRVGKMDATVHSSIASEFGVRGFPTIKVLKGDMAYNYRGPRTKEDIVEFANRVAGPLIRPLPSQQMFDHVQKRH--SVLFVYVGVEST-LKEKYIEVASELIVYTYFFSSSEDVLPK----YVTLN------EVPAVLVFKDSTYFVYDEYE-----DGDLSSWVNKERFEGYLHIDGFTLYELGDTGSLVSIIISAACY-----------------------FSLKYVAKNYRDHFHRDFQFGHMDGNDYINSLLMDELSIPTFVVLNTSNQQYFLPS-----KQIENTEEMI--QFINSILDGTAEAQGGDGILQRIKRVFYDAKSTVVSVFKSSPLLGCFLFGLPLGVISIMCYGICTADTEDG 395
BLAST of SMED30003142 vs. Ensembl Xenopus
Match: nup35 (nucleoporin 35kDa [Source:Xenbase;Acc:XB-GENE-980941]) HSP 1 Score: 162.54 bits (410), Expect = 2.235e-43 Identity = 112/403 (27.79%), Postives = 193/403 (47.89%), Query Frame = -1 Query: 421 WLVKFYAPWCGYCRKLEPIYNE--LEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLF----SFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDA 1611 WL FYAPWCG+C+KLEP++NE +E PI++ ++DAT + +AS + +RG+PTIK + G Y + G RT E ++ F+ R GP ++ LPS+ F + H F+Y+G S+ LK Y ++A+ L + +YF+S +P+ ++ LN E +LV+K + E + L +W++ RF + I L+ + + + +++ E S ++ L SF F+ + + ND +N L M L +P ++ N ++ ++++ +E F++S G E GG G +++R YD + ++ ++P+L F+ G+PL VIS +CY IC DT D Sbjct: 26 WL--FYAPWCGHCKKLEPVWNEVGIEMRSSGSPIRVGKMDATVHSSIASEFGVRGFPTIKVLKGDMAYNYRGPRTKEDIVEFANRVAGPLIRPLPSQQMFDHVQKRH--SVLFVYVGVEST-LKEKYIEVASELIVYTYFFSSSEDVLPK----YVTLN------EVPAVLVFKDSTYFVYDEYE-----DGDLSSWVNKERFEGYLHIDGFTLY---------ELGDTGKLVAVAVIDEKNNSVEHTSVSVTLLYRFCSFLVGRDFQFGHMDGNDY----------INSLLMDELSIPTFVVLNTSNQQYFLPS-----KQIENTEEMI--QFINSILDGTAEAQGGDGILQRIKRVFYDAKSTVVSVFKSSPLLGCFLFGLPLGVISIMCYGICTADTEDG 382
BLAST of SMED30003142 vs. Ensembl Xenopus
Match: nup35 (nucleoporin 35kDa [Source:Xenbase;Acc:XB-GENE-980941]) HSP 1 Score: 162.155 bits (409), Expect = 2.542e-43 Identity = 110/400 (27.50%), Postives = 192/400 (48.00%), Query Frame = -1 Query: 421 KFYAPWCGYCRKLEPIYNE--LEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLF----SFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDA 1602 +FYAPWCG+C+KLEP++NE +E PI++ ++DAT + +AS + +RG+PTIK + G Y + G RT E ++ F+ R GP ++ LPS+ F + H F+Y+G S+ LK Y ++A+ L + +YF+S +P+ ++ LN E +LV+K + E + L +W++ RF + I L+ + + + +++ E S ++ L SF F+ + + ND +N L M L +P ++ N ++ ++++ +E F++S G E GG G +++R YD + ++ ++P+L F+ G+PL VIS +CY IC DT D Sbjct: 20 QFYAPWCGHCKKLEPVWNEVGIEMRSSGSPIRVGKMDATVHSSIASEFGVRGFPTIKVLKGDMAYNYRGPRTKEDIVEFANRVAGPLIRPLPSQQMFDHVQKRH--SVLFVYVGVEST-LKEKYIEVASELIVYTYFFSSSEDVLPK----YVTLN------EVPAVLVFKDSTYFVYDEYE-----DGDLSSWVNKERFEGYLHIDGFTLY---------ELGDTGKLVAVAVIDEKNNSVEHTSVSVTLLYRFCSFLVGRDFQFGHMDGNDY----------INSLLMDELSIPTFVVLNTSNQQYFLPS-----KQIENTEEMI--QFINSILDGTAEAQGGDGILQRIKRVFYDAKSTVVSVFKSSPLLGCFLFGLPLGVISIMCYGICTADTEDG 375
BLAST of SMED30003142 vs. Ensembl Xenopus
Match: nup35 (nucleoporin 35kDa [Source:Xenbase;Acc:XB-GENE-980941]) HSP 1 Score: 146.747 bits (369), Expect = 1.202e-37 Identity = 114/419 (27.21%), Postives = 189/419 (45.11%), Query Frame = -1 Query: 421 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNE--LEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLF----SFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDA 1659 V +L+ +F E WLV FYAPWCG+C+KLEP++NE +E PI++ ++DAT + +AS + +RG+PTIK + G Y + G RT E ++ F+ R GP ++ LPS+ F + H F+Y+G S+ LK Y ++A+ L + +YF+S +P+ ++ LN E +LV+K + E + L +W++ RF + I L+ + + + +++ E S ++ L SF F+ + + ND +N L M L +P ++ N Y P + I +F++ L + E+ F K ++P+L F+ G+PL VIS +CY IC DT D Sbjct: 28 VEDLDDSFKENRKDDIWLVDFYAPWCGHCKKLEPVWNEVGIEMRSSGSPIRVGKMDATVHSSIASEFGVRGFPTIKVLKGDMAYNYRGPRTKEDIVEFANRVAGPLIRPLPSQQMFDHVQKRH--SVLFVYVGVEST-LKEKYIEVASELIVYTYFFSSSEDVLPK----YVTLN------EVPAVLVFKDSTYFVYDEYE-----DGDLSSWVNKERFEGYLHIDGFTLY---------ELGDTGKLVAVAVIDEKNNSVEHTSVSVTLLYRFCSFLVGRDFQFGHMDGNDY----------INSLLMDELSIPTFVVLNTSNQQ-YFLPSKQIENTEEMI--QFINSILDG--TAEVSCLPTCFFCLKQS------------VFKSSPLLGCFLFGLPLGVISIMCYGICTADTEDG 392
BLAST of SMED30003142 vs. Ensembl Mouse
Match: Tmx3 (thioredoxin-related transmembrane protein 3 [Source:MGI Symbol;Acc:MGI:2442418]) HSP 1 Score: 170.244 bits (430), Expect = 5.233e-46 Identity = 123/425 (28.94%), Postives = 200/425 (47.06%), Query Frame = -1 Query: 397 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESST--MKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADNRRIEAR 1659 V +LN +F + WLV FYAPWCG+C+KLEPI+NE+ +K + P+K+ ++DAT Y +AS + +RGYPTIK + G Y + G RT + +I F+ R G ++ LPS+ F + H FF+YIG S LK Y D A+ L + +YF+S +P+ Y L E +LV+K D + E + L +WIS RF + + L+ + + E+ +S +L S +++A + + D F +N L M L VP +++ N ++ + + K D + F++S G + GG +++R +D + ++ ++P++ F+ G+PL VIS +CY I T+D D IE R Sbjct: 31 VEDLNESFKDNRKDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFDHVRKRH--RVFFVYIGGESP-LKEKYIDAASELIVYTYFFSASEDVVPE--YVTL--------KEMPAVLVFKDDTYFVYDEYE-----DGDLSSWISRERFQNYLTMDGFLLY---------------ELGDTGKLVAIAVIDEKNTSLEHTRLKSIIQEVARDFRDHFHRDFQFGHMDGNDYINTLLMDELTVPTIVVLNTSNQQYFLL---DRHIK----DASDMVQFINSILDGTVPAQGGDSIFQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIY---TADTDGGYIEER 412
BLAST of SMED30003142 vs. Ensembl Mouse
Match: Tmx3 (thioredoxin-related transmembrane protein 3 [Source:MGI Symbol;Acc:MGI:2442418]) HSP 1 Score: 137.887 bits (346), Expect = 3.629e-35 Identity = 82/222 (36.94%), Postives = 120/222 (54.05%), Query Frame = -1 Query: 1000 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTF 1659 V +LN +F + WLV FYAPWCG+C+KLEPI+NE+ +K + P+K+ ++DAT Y +AS + +RGYPTIK + G Y + G RT + +I F+ R G ++ LPS+ F + H FF+YIG S LK Y D A+ L + +YF+S +P+ Y L E +LV+K D + E + L +WIS RF + Sbjct: 31 VEDLNESFKDNRKDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFDHVRKRH--RVFFVYIGGESP-LKEKYIDAASELIVYTYFFSASEDVVPE--YVTL--------KEMPAVLVFKDDTYFVYDEYE-----DGDLSSWISRERFQNY 234
BLAST of SMED30003142 vs. Ensembl Mouse
Match: Pdia4 (protein disulfide isomerase associated 4 [Source:MGI Symbol;Acc:MGI:104864]) HSP 1 Score: 80.4925 bits (197), Expect = 2.429e-15 Identity = 36/86 (41.86%), Postives = 55/86 (63.95%), Query Frame = -1 Query: 1378 IADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIK--DLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLI 1629 +ADK L++FYAPWCG+C++ P Y ++ + +K D PI +A+IDAT +AS + + GYPTIK + +DG RT E ++ Sbjct: 72 VADKDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSASMLASKFDVSGYPTIKILKKGQAVDYDGSRTQEEIV 157 HSP 2 Score: 75.8702 bits (185), Expect = 7.945e-14 Identity = 44/136 (32.35%), Postives = 73/136 (53.68%), Query Frame = -1 Query: 1213 LVKFYAPWCGYCRKLEPIYNELEAHI--KDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAI-ESHLMETFFLYIGDRS-SYLKAVYDDLANSLR 1608 LV+FYAPWCG+C+KL P Y + + + PI +A++DAT D+A + + GYPT+K + ++G R ++ + GP K + + + E + + + L+ GD +YL+ Y D AN+LR Sbjct: 194 LVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTDLAKRFDVSGYPTLKIFRKGRPFDYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVVIIGLFQGDGDPAYLQ--YQDAANNLR 327 HSP 3 Score: 64.3142 bits (155), Expect = 3.200e-10 Identity = 34/84 (40.48%), Postives = 48/84 (57.14%), Query Frame = -1 Query: 1372 LVKFYAPWCGYCRKLEPIYNELEAHIKDLP-IKIARIDATRYPDVASFYQIRGYPTIKYINGTD----IYTHDGDRTVEHLILF 1608 L++FYAPWCG+C++LEPIY L K + IA++DAT Y++ G+PTI + D I G+R +EHL F Sbjct: 543 LIEFYAPWCGHCKQLEPIYTSLGKKYKGQKDLVIAKMDATANDITNDQYKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLSKF 626
BLAST of SMED30003142 vs. Ensembl Mouse
Match: Pdia3 (protein disulfide isomerase associated 3 [Source:MGI Symbol;Acc:MGI:95834]) HSP 1 Score: 78.5666 bits (192), Expect = 9.141e-15 Identity = 47/151 (31.13%), Postives = 79/151 (52.32%), Query Frame = -1 Query: 1240 NVIELN-----SNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIK-YINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAI--ESHLMETFF--LYIGDRSSYLKAV 1662 +V+EL S + G LV+F+APWCG+C++L P Y +K + + +A++D T + + Y + GYPT+K + +G + +DG RT + ++ K+ GPA L +E F + I + + FF L+ S +LKA Sbjct: 26 DVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGI-VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASVVGFFRDLFSDGHSEFLKAA 175 HSP 2 Score: 67.3958 bits (163), Expect = 2.959e-11 Identity = 37/86 (43.02%), Postives = 53/86 (61.63%), Query Frame = -1 Query: 1363 LVKFYAPWCGYCRKLEPIYNEL-EAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYT---HDGDRTVEHLILFSKR 1608 L++FYAPWCG+C+ LEP Y EL E KD I IA++DAT DV S Y+++G+PTI + T ++G R + I + +R Sbjct: 398 LIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAN-DVPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFISYLQR 482
BLAST of SMED30003142 vs. Ensembl Mouse
Match: Pdia6 (protein disulfide isomerase associated 6 [Source:MGI Symbol;Acc:MGI:1919103]) HSP 1 Score: 74.7146 bits (182), Expect = 1.114e-13 Identity = 41/116 (35.34%), Postives = 63/116 (54.31%), Query Frame = -1 Query: 1291 WLVKFYAPWCGYCRKLEPIYNELEAHIKDL---PIKIARIDATRYPDVASFYQIRGYPTIK-YINGTDIYTHDGDRTVEHLI-----LFSKRALGPAVKHLPSEGRFHEAIESHLM 1611 W+V+FYAPWCG+C+ LEP + +K+ +K+A +DAT +AS Y I+G+PTIK + G +DG RT ++ LFS A P + + +E + E H + Sbjct: 186 WMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATMNQVLASRYGIKGFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKKTCEEHQL 301 HSP 2 Score: 73.1738 bits (178), Expect = 3.339e-13 Identity = 41/112 (36.61%), Postives = 63/112 (56.25%), Query Frame = -1 Query: 1342 NVIELN-SNFIE--IADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHD--GDRTVEHLILFSKRALGPAVK 1662 +VIEL SNF I G WLV+FYAPWCG+C++L P + + +KD+ +K+ ++A ++ + Y ++G+PTIK D G RT E ++ + AL VK Sbjct: 31 DVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATALKDV-VKVGAVNADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVK 141
BLAST of SMED30003142 vs. UniProt/SwissProt
Match: sp|Q6GNG3|TMX3_XENLA (Protein disulfide-isomerase TMX3 OS=Xenopus laevis OX=8355 GN=tmx3 PE=2 SV=1) HSP 1 Score: 177.948 bits (450), Expect = 4.949e-48 Identity = 120/417 (28.78%), Postives = 198/417 (47.48%), Query Frame = -1 Query: 421 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIK--DLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESST--MKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDA 1659 V +L+ +F E WLV FYAPWCG+C+KLEP++NE+ I+ PI++ +IDAT Y +AS + +RG+PTIK + G Y + G RT E ++ F+ R GP ++ LPS+ F + H F+Y+G S+ LK + ++A+ L + +YF+S +P+ ++ LN E +LV+K + E + L +W++ RF + I L+ + + E+ +S ++ S A+ +A + N+ D F +N L M L +P ++ N Y P + + I F++S G E GG G +++R YD + ++ ++P+L F+ G+PL VIS +CY IC DT D Sbjct: 28 VEDLDDSFKENRKDDIWLVDFYAPWCGHCKKLEPVWNEVGIEIRTSGSPIRVGKIDATVYSSIASEFGVRGFPTIKALKGDMAYNYRGPRTKEDIVEFANRVAGPLIRPLPSQQMFDHVKKRH--PVLFVYVGVEST-LKEKFIEVASELIVYTYFFSASEDVLPK----YVTLN------EVPAVLVFKDSTYFVYDEYE-----DGDLSSWVNKERFEGYLHIDGFTLY---------------ELGDTGKLVAVAVIDEKNNSIEHTRIKSIAQDVAKNNRNNFHRDFQFGHMDGNDYINSLLMDELSIPTFVVLNTSNQQ-YFLPSKHIENPEEMI------QFINSILDGTAEAQGGDGILQRIKRVFYDAKSTVVSVFKSSPLLGCFLFGLPLGVISIMCYGICTADTEDG 404
BLAST of SMED30003142 vs. UniProt/SwissProt
Match: sp|Q5R875|TMX3_PONAB (Protein disulfide-isomerase TMX3 OS=Pongo abelii OX=9601 GN=TMX3 PE=2 SV=1) HSP 1 Score: 175.252 bits (443), Expect = 5.832e-47 Identity = 122/425 (28.71%), Postives = 206/425 (48.47%), Query Frame = -1 Query: 397 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESST--MKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADNRRIEAR 1659 V +L+ +F E + WLV FYAPWCG+C+KLEPI+NE+ +K + P+K+ ++DAT Y +AS + +RGYPTIK + G Y H G RT + +I F+ R G ++ LPS+ F + H FF+YIG S LK Y D A+ L + +YF+S + +P+ Y L E +LV+K + + E + L +WI+ RF + + L+ + + E+ +S +L S +++A + + D F +N L M L VP V++ N ++ +++K +++ + F+++ G +E GG +++R +D + ++ ++P++ F+ G+PL VIS +CY I T+D D IE R Sbjct: 28 VEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNHRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRH--RVFFVYIGGESP-LKEKYIDAASELIVYTYFFSASEEVVPE--YVTL--------KEMPAVLVFKDETYFVYDEYE-----DGDLSSWINRERFQNYLAMDGFLLY---------------ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLLMDELTVPTVVVLNTSNQQYFLLD-----RQIKNVED--MVQFINNILDGTVEAQGGDSILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIY---TADTDGGYIEER 409
BLAST of SMED30003142 vs. UniProt/SwissProt
Match: sp|Q96JJ7|TMX3_HUMAN (Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2) HSP 1 Score: 172.555 bits (436), Expect = 4.474e-46 Identity = 120/425 (28.24%), Postives = 206/425 (48.47%), Query Frame = -1 Query: 397 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESST--MKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADNRRIEAR 1659 V +L+ +F E + WLV FYAPWCG+C+KLEPI+NE+ +K + P+K+ ++DAT Y +AS + +RGYPTIK + G Y + G RT + +I F+ R G ++ LPS+ F + H FF+Y+G S LK Y D A+ L + +YF+S + +P+ Y L E +LV+K + + E + L +WI+ RF + + L+ + + E+ +S +L S +++A + + D F +N L M L VP V++ N ++ +++K +++ + F+++ G +E GG +++R +D + ++ ++P++ F+ G+PL VIS +CY I T+D D IE R Sbjct: 28 VEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRH--RVFFVYVGGESP-LKEKYIDAASELIVYTYFFSASEEVVPE--YVTL--------KEMPAVLVFKDETYFVYDEYE-----DGDLSSWINRERFQNYLAMDGFLLY---------------ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLLMDELTVPTVVVLNTSNQQYFLLD-----RQIKNVED--MVQFINNILDGTVEAQGGDSILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIY---TADTDGGYIEER 409
BLAST of SMED30003142 vs. UniProt/SwissProt
Match: sp|Q8BXZ1|TMX3_MOUSE (Protein disulfide-isomerase TMX3 OS=Mus musculus OX=10090 GN=Tmx3 PE=1 SV=2) HSP 1 Score: 170.244 bits (430), Expect = 3.660e-45 Identity = 123/425 (28.94%), Postives = 200/425 (47.06%), Query Frame = -1 Query: 397 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESST--MKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADNRRIEAR 1659 V +LN +F + WLV FYAPWCG+C+KLEPI+NE+ +K + P+K+ ++DAT Y +AS + +RGYPTIK + G Y + G RT + +I F+ R G ++ LPS+ F + H FF+YIG S LK Y D A+ L + +YF+S +P+ Y L E +LV+K D + E + L +WIS RF + + L+ + + E+ +S +L S +++A + + D F +N L M L VP +++ N ++ + + K D + F++S G + GG +++R +D + ++ ++P++ F+ G+PL VIS +CY I T+D D IE R Sbjct: 31 VEDLNESFKDNRKDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFDHVRKRH--RVFFVYIGGESP-LKEKYIDAASELIVYTYFFSASEDVVPE--YVTL--------KEMPAVLVFKDDTYFVYDEYE-----DGDLSSWISRERFQNYLTMDGFLLY---------------ELGDTGKLVAIAVIDEKNTSLEHTRLKSIIQEVARDFRDHFHRDFQFGHMDGNDYINTLLMDELTVPTIVVLNTSNQQYFLL---DRHIK----DASDMVQFINSILDGTVPAQGGDSIFQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIY---TADTDGGYIEER 412
BLAST of SMED30003142 vs. UniProt/SwissProt
Match: sp|O13704|YEU5_SCHPO (Thioredoxin domain-containing protein C13F5.05, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC13F5.05 PE=4 SV=2) HSP 1 Score: 89.7373 bits (221), Expect = 4.934e-18 Identity = 77/234 (32.91%), Postives = 116/234 (49.57%), Query Frame = -1 Query: 1000 NVIELNS-NFIE-IADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKD-LPIKIARIDATRYPDVASFYQIRGYPTIKYI------NGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLN-SSLSDTENGTILVWK-PDRKLSFHFKEEIS--SLNHSLQNWISFNRFSTF 1662 N IELNS NF + + KGP LV FYAPWCGYC+KL P Y +L +++ LP+ DA + V S YQ++G+PTIK + + ++GDR+ + L F ++ VK L SE + + I+ + + I + +Y L+N F S+ F+P + N S+ DT + IL K P+ SF F ++ S+ LQ+ I N FS + Sbjct: 32 NTIELNSKNFRKFVKAKGPSLVVFYAPWCGYCKKLVPTYQKLASNLHSLLPVTAVDCDADQNRAVCSQYQVQGFPTIKLVYPSSKGSSLSSTDYNGDRSYKSLQKFVSDSIPSKVKILTSEAKTQKFIQDAQNSSKVILISQKMK-PTLLYKSLSNE------FSSLPFSFMPAKANVNDLFNISAYVDTSDLPILFIKHPNNGTSF-FSNSLNRDSIVEFLQSSIKDNNFSEY 257
BLAST of SMED30003142 vs. TrEMBL
Match: A0A210QUZ2 (Protein disulfide-isomerase TMX3 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT13753 PE=4 SV=1) HSP 1 Score: 240.35 bits (612), Expect = 1.067e-68 Identity = 127/415 (30.60%), Postives = 230/415 (55.42%), Query Frame = -1 Query: 424 NVIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIG--DRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSD 1662 V+EL+ F+++ + PWLV+FYAPWCG+C+KLEP ++++ +++ P+K+ ++D TR+ VAS + ++G+PTIK+ NG +IYTH GDRT E ++ F RA GPAV++L S+G+F EA H FFLY+G D + + Y ++A + ++SYFY+ + +PQ + T+L +K + + ++ I +++ SLQ+WI+ RF FP ++ ++ I S + + + +N E ++ + ++ K LA + + + F+W +D+ ++N +AM + P V++ P H Y+ M+ + + +L + ++ GG GF +++R YD I ++ ++ L + + G+P +VIS +CY++CCMDT D Sbjct: 24 QVLELDERFLDVYKEVPWLVEFYAPWCGHCKKLEPTFHQVSMSLRNTPVKVGKLDCTRFSSVASEFSVKGFPTIKFFNGENIYTHRGDRTKEDIMEFVNRAKGPAVRNLASKGKFEEAKNQHKDSAFFLYLGRQDPVDDMFSKYSNVAEQMLIQSYFYAGNSAVLPQ----------RIKPAVTPTVLAFKDQEVVEYKAQDGIVTMS-SLQDWINSERFPAFPLVTGANI-----------NDIAESGKILVMMAFDDENTESKAGSERIKDMVKVLATQHKDRFHSGFQFLWMSDMETVNSIAMAFMKGPVVMLLNPTTHYYYMPLTPIQDMAMEQLMQ-----YLEDVRDEKVPALGGTGFFQRLKRVFYDLIVMVVGVWQSSRWLFLLMFGLPTTVISVVCYSLCCMDTVD 411
BLAST of SMED30003142 vs. TrEMBL
Match: A0A267EQ68 (Thioredoxin domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009031g3 PE=4 SV=1) HSP 1 Score: 226.483 bits (576), Expect = 3.126e-63 Identity = 131/418 (31.34%), Postives = 211/418 (50.48%), Query Frame = -1 Query: 424 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENG------TILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSD 1659 V+E+ FI +LVKFYAPWCG+CR +EP Y E+ + P+ +ARIDAT + A+ +++RG+PT+ Y+ G + G+RT + ++ F R G VK + S G+F+E + + + FFL+IG S AV++ +A +R S FY + Q + + DL + D +G +L +K + + F + + N SL W++ RF +PK+ + S S E + + + LAF S + E ++ F W+ + +D+AMT+L PNV++ P + Y+ PD + ++ + + +GE+ YGG G ++R YDF TGL FV + P LA+ +IG P++V+S LCYAICCMDT+D Sbjct: 38 VVEVGEEFIGRDASQAFLVKFYAPWCGHCRNMEPAYEEVSDRLAGSPVTVARIDATVHQAAAAHFRVRGFPTLIYVKGDTRHEFRGERTADEIVKFVNRVSGDPVKVIASPGKFNEVFATSVKDPFFLFIGSEESKEFAVFNGIAGQMRTDSSFYRADAQLLANLGF---DLAAKRLDRGHGGDIAEPCVLAFKDNGFVLFRGQFD----NDSLGVWMTNERFHIYPKLGDFLFY---------------SFYPSTKLLVAIVTNESDPEERRFVQLGRALAF-SMDLELANVQFGWAGSAKAASDMAMTSLPTPNVMLLNPNSTRYYLRPDYHLPISVRDETVGSLKRLVLQGLNGELPAYGGGGLIEGLKRTVYDFATGLAGFVLSHPGLALVVIGAPVAVVSILCYAICCMDTTD 432
BLAST of SMED30003142 vs. TrEMBL
Match: A0A2T7NH06 (Thioredoxin domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_18619 PE=4 SV=1) HSP 1 Score: 223.787 bits (569), Expect = 1.274e-62 Identity = 131/446 (29.37%), Postives = 237/446 (53.14%), Query Frame = -1 Query: 340 NFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSY--LKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQ--PWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCM---DTSDADNRRIEARQQKK-----IRIPLYEVALKSSEE 1641 +F+E WLV+FYAPWCG+C+KLEP+Y E+ +++ P+K+ ++D TR+ D+A+ + IRG+PTIK++ G ++TH GDR+ E ++ F+ RA GPAV+ L S G+ +EA H E FFLYIGD L Y +A+ + ++ Y+Y+ + + +S + T+L +K + F E ++++ +L++WI+ R+ FP+I W I L+ ++ I + ++ +L + A+ +A + + ++ F+W TD+ ++N + M+ L P +L+ + P + + P SN I FL ++G ++ +GG GF +++R YD +T +I + L + + G+P +IS +CY++CCM D S ++ E RQ ++ + P Y+ LK+ ++ Sbjct: 4 SFLEKKGDDMWLVEFYAPWCGHCKKLEPVYREVAHELRNSPVKVGKVDCTRFTDLAAHFSIRGFPTIKFVKGNQVFTHRGDRSKEGILEFASRAQGPAVRKLSSVGKLNEARSKHSDEVFFLYIGDDDEQDDLYQKYQTVADKMMVQGYYYAGKKHIL-----------EDISTKNHPTVLAFKDRMQYEFLPPEGVATM-EALEHWINTERYPAFPQI-----W------GGAINLLADTKKYLVIIVVDPEIKDKMDGNNRLKNIAEAIALDQRDKYHSEFQFLWMTDVETVNTITMSFLTPPVLLVLEVDPQYYYLPDLPASN-------ITINTFMQFLDGIRNGTVQAHGGNGFFMRVKRLLYDIMTTIISIWQASRWLFLLVFGLPTLIISIICYSLCCMEPLDDSYLEDEEDELRQLQQESAGDAKAPDYDEELKNEQD 419
BLAST of SMED30003142 vs. TrEMBL
Match: V4B8B0 (Thioredoxin domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_206090 PE=4 SV=1) HSP 1 Score: 223.016 bits (567), Expect = 1.770e-62 Identity = 126/405 (31.11%), Postives = 211/405 (52.10%), Query Frame = -1 Query: 424 GPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLP--IKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYI--GDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQ---NDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSD 1617 G WL++FYAPWCG+CRKLEP+Y ++ +K+ + +++IDATRY +VAS + +RG+PT+K++NG +YTH GDR+ E ++ F +A GPAV+++ S G+F+E H FF+++ GD + L Y LA + SYFYS +P ++ T+LV+K F E L+ W++ RF FPK+ L N + + + S + K ++ + N Q D F+W D + N + M+ L +P++++ + + YI D N + + E+ + DFL + G+++ YGG GF +K++RAG+DF+T ++ + L + + G+P +IS +CY++CCM+T D Sbjct: 5 GMWLIEFYAPWCGHCRKLEPVYRQVFTELKNSGSGVIVSKIDATRYSNVASEFDVRGFPTLKFVNGDKVYTHRGDRSKEDILDFVNKAKGPAVRNIASVGKFNEIKTLHGKSVFFMFVGNGDENDDLFKKYSSLAEKHIIESYFYSGPKNSLPD----------KVTIKTFPTVLVFKDKNIFEFDVGESEVVTKDKLEKWLNRERFPAFPKVQGGGL---------------NELVTAAKYLVIVVVNKDSSVKNECKKVKKVVSNVALNHRQKYHQDFQFLWMPDEETANSITMSFLNIPSIVVLETASQLHYI-SDKN----VTDLTEQSIQDFLDGIKVGKVDAYGGTGFLSKLKRAGFDFLTTVLSIWQASRWLFLLMFGLPTVIISVVCYSLCCMETID 379
BLAST of SMED30003142 vs. TrEMBL
Match: A0A0X3PAE8 (Protein disulfide-isomerase TMX3 OS=Schistocephalus solidus OX=70667 GN=TMX3 PE=4 SV=1) HSP 1 Score: 223.787 bits (569), Expect = 6.489e-62 Identity = 130/427 (30.44%), Postives = 220/427 (51.52%), Query Frame = -1 Query: 385 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHI-KDLP-IKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADNRRIEARQQKK 1659 VIEL S I G WL+KFYAPWC +CR+LEP+Y+E+ + + LP + +ARID P V++ + IRGYPTI +++ Y + G+R + L+ F RA GPAVK L S+ + ++ H E F++ G S L Y+ +A+ LRL+ F ++E P+ + ++ V+K SF + + L ++ W+ R F +IS + + I + +S+ + E + ++ +L + LA + + FVW +D+ S++ L MT+L PN+ ++ P +HP N+ ++++ + V +FL + SGE+ YGG G A+++RA Y+F +G+++ V +P+LA+ + G PL +S LCY IC D D +E R + + Sbjct: 25 VIELTSESISKVHTGLWLLKFYAPWCSFCRQLEPVYHEVALTLSRILPEVHVARIDVPANPAVSADFGIRGYPTIIFLHNGHRYPYQGERAADDLVKFVIRASGPAVKKLGSQEELGKELQVHKDEALFVFSGSTKSALWEAYNKVADELRLQVSFVALEKDVSPEPV--------------SASLRVFKDGIHFSFKPQADADDLREEVRRWVLLERHPAFQRISALGI-----RRLVAEINLVSSAQSLSLVVFVLSPDETDVASHRLKTIGSSLASDRSDSLLQHFRFVWCSDVDSVSRLVMTSLQPPNLFVYGP-EDIFALHPLYNSIKELRELTAVEVRNFLKAVASGEVRTYGGSGIFARLKRASYEFTSGVLDLVYNSPVLALLVFGFPLGCLSCLCYCICWGSFED-DPEAVEFRARSR 430
BLAST of SMED30003142 vs. Ensembl Cavefish
Match: tmx3a (protein disulfide-isomerase TMX3-like [Source:NCBI gene;Acc:103028107]) HSP 1 Score: 136.732 bits (343), Expect = 2.178e-34 Identity = 103/369 (27.91%), Postives = 171/369 (46.34%), Query Frame = -1 Query: 565 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTI--YIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKM 1659 V EL+ F + PWLV+FYAPWC +C+ EPI+ E+ A +K L P+ + +ID T Y +VA+ Y IRGYP I + G Y + G RT + ++ F+ R GP V+ L S F A H + FFLYIG RS LK +Y +A + +YF+S +P+S L +++ ++GT V+ + + +L W+ RF + ++ L+ + + + +++ S +K+A E + + D F + +N M L +P++++ N TI Y P+S K++ +E + FL S G+ + GG GF ++ Sbjct: 23 VEELDDKFNDFRKSEPWLVEFYAPWCEFCKTFEPIWYEVGAELKSLGSPVTVGKIDTTVYTNVATEYAIRGYPAIILLKGEKSYEYKGPRTKDGILEFTNRVAGPVVRSLTSAQLFQHATSRH--DLFFLYIGGRSP-LKGLYYKVAADFIIHNYFFSAPEDVLPKSV--TLQEVPAVAVFKDGTYYVYNEEH-------------DGNLSAWVDQERFRCYFQMDSFTLY-------------QMGDRTKLVALTVLEEKNPSADSIRYKSLMEKVATEYRDHYKTDFQFGYMHGNDYINGFIMGELEIPSLIVM---NMTIDGYYLPES----KIETTEE--LLQFLSSVLDGQSQLLGGNGFLRRI 351
BLAST of SMED30003142 vs. Ensembl Cavefish
Match: tmx3a (protein disulfide-isomerase TMX3-like [Source:NCBI gene;Acc:103028107]) HSP 1 Score: 136.732 bits (343), Expect = 2.178e-34 Identity = 103/369 (27.91%), Postives = 171/369 (46.34%), Query Frame = -1 Query: 565 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTI--YIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKM 1659 V EL+ F + PWLV+FYAPWC +C+ EPI+ E+ A +K L P+ + +ID T Y +VA+ Y IRGYP I + G Y + G RT + ++ F+ R GP V+ L S F A H + FFLYIG RS LK +Y +A + +YF+S +P+S L +++ ++GT V+ + + +L W+ RF + ++ L+ + + + +++ S +K+A E + + D F + +N M L +P++++ N TI Y P+S K++ +E + FL S G+ + GG GF ++ Sbjct: 23 VEELDDKFNDFRKSEPWLVEFYAPWCEFCKTFEPIWYEVGAELKSLGSPVTVGKIDTTVYTNVATEYAIRGYPAIILLKGEKSYEYKGPRTKDGILEFTNRVAGPVVRSLTSAQLFQHATSRH--DLFFLYIGGRSP-LKGLYYKVAADFIIHNYFFSAPEDVLPKSV--TLQEVPAVAVFKDGTYYVYNEEH-------------DGNLSAWVDQERFRCYFQMDSFTLY-------------QMGDRTKLVALTVLEEKNPSADSIRYKSLMEKVATEYRDHYKTDFQFGYMHGNDYINGFIMGELEIPSLIVM---NMTIDGYYLPES----KIETTEE--LLQFLSSVLDGQSQLLGGNGFLRRI 351
BLAST of SMED30003142 vs. Ensembl Cavefish
Match: pdia3 (protein disulfide isomerase family A member 3 [Source:NCBI gene;Acc:103022595]) HSP 1 Score: 90.5077 bits (223), Expect = 8.351e-19 Identity = 64/237 (27.00%), Postives = 116/237 (48.95%), Query Frame = -1 Query: 985 NVIELNSNFIE--IADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIK-YINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSL--SDTENGTILVWKPDRKLSFHFKE------EISSLNHSLQNWISFNRFSTFPKISQ 1662 +VIE + E I D LV+F+APWCG+C++L P Y +K + + +A++D T +V S Y + GYPT+K + +G + +DG RT + ++ K+ GPA ++E + F +IGDR + + + D ++ +S F + ++H +L L SD + +++++P R L+ F+E E N ++ +I N F P +++ Sbjct: 18 DVIEFTDDDFENKIGDHDLILVEFFAPWCGHCKRLAPEYEAAATRLKGI-VSLAKVDCTANSNVCSKYGVSGYPTLKIFRDGEESGAYDGPRTADGIVSHLKKQAGPA------------SVELKTVADFEKFIGDRDASVVGFFADGGSA--AQSEFLKSASALRESYRFAHTNLEDLLKKSDIDGEGVVLFRPPR-LNNKFEESSVKFSEDKFTNAKIKRFIQDNIFGMCPHMTE 238 HSP 2 Score: 67.3958 bits (163), Expect = 1.861e-11 Identity = 39/103 (37.86%), Postives = 58/103 (56.31%), Query Frame = -1 Query: 1363 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLP-IKIARIDATRYPDVASFYQIRGYPTIKYI---NGTDIYTHDGDRTVEHLILFSKR 1659 V+ N + I D L++FYAPWCG+C+ LEP Y EL + + P + IA++DAT DV S Y +RG+PTI + + ++G R V I + K+ Sbjct: 370 VVAENFDSIVNDDSKDVLIEFYAPWCGHCKSLEPKYKELGEKLANDPNVVIAKMDATAN-DVPSSYDVRGFPTIYFSPAGQKQNPKRYEGGREVSDFISYLKK 471
BLAST of SMED30003142 vs. Ensembl Cavefish
Match: pdia4 (protein disulfide isomerase family A member 4 [Source:NCBI gene;Acc:103026638]) HSP 1 Score: 77.7962 bits (190), Expect = 1.403e-14 Identity = 35/94 (37.23%), Postives = 57/94 (60.64%), Query Frame = -1 Query: 1333 LVKFYAPWCGYCRKLEPIYNELEAHIK--DLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLP 1608 LV+FYAPWCG+C++ P Y ++ +K D PI +A++DAT+ + S +++ GYPTIK + + +DGDR+ + ++ K P K P Sbjct: 82 LVEFYAPWCGHCKQFAPEYEKIAQVLKESDPPIPVAKVDATKATALGSRFEVSGYPTIKILKKGEPVEYDGDRSEKAIVERVKEVAQPDWKPPP 175 HSP 2 Score: 77.7962 bits (190), Expect = 1.517e-14 Identity = 57/212 (26.89%), Postives = 101/212 (47.64%), Query Frame = -1 Query: 1000 LVKFYAPWCGYCRKLEPIYNELEAHI--KDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYD---DLANSLR----LRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTF 1608 LV+FYAPWCG+C++L P Y + + + PI +A++DAT D+AS + + GYPT+K ++ ++G R ++ + GP K + + + E ++ L +G SS AVY+ + N+LR R F S +F+ S G +++ +P++ F K E SS + ++++ S + F Sbjct: 197 LVEFYAPWCGHCKRLAPEYEKAAKELSNRTPPILLAKVDATVENDLASRFDVTGYPTLKMFRKGKVFDYNGPREKIGIVDYMSEQAGPPSKQVQALKQIQELLKDG---DDALIVGVFSSEEDAVYEIYQEACNTLRDDYKFRHTFSSEIVKFLKAS---------------PGQVVMLQPEK---FRSKHEPSSYSFTIKDSTSASELQDF 387 HSP 3 Score: 56.6102 bits (135), Expect = 6.648e-8 Identity = 32/84 (38.10%), Postives = 46/84 (54.76%), Query Frame = -1 Query: 1372 LVKFYAPWCGYCRKLEPIYNELEAHIKDLP-IKIARIDATRYPDVASFYQIRGYPTIKYINGTD----IYTHDGDRTVEHLILF 1608 L++FYAPWCG+C+KLEP Y L K+ + IA++DAT Y++ G+PTI + + I G+R VE F Sbjct: 545 LIEFYAPWCGHCKKLEPDYLALAKKYKNEKNLVIAKMDATANDVPHDSYKVEGFPTIYFAPSNNKQNPIKFEGGERNVEGFSKF 628
BLAST of SMED30003142 vs. Ensembl Cavefish
Match: PDIA6 (protein disulfide-isomerase A6 [Source:NCBI gene;Acc:103027650]) HSP 1 Score: 77.0258 bits (188), Expect = 1.577e-14 Identity = 73/262 (27.86%), Postives = 118/262 (45.04%), Query Frame = -1 Query: 973 NVIEL-NSNFIEIADKGP--WLVKFYAPWCGYCRKLEPIYNELEAHIKDL---PIKIARIDATRYPDVASFYQIRGYPTIK-YINGTDIYTHDGDRTVEHLI-----LFSKRALGPAVKHLPSEGRFHE----------AIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENG-TILVWKPDRKLSFH-FKEEISSLN-HSLQNWISFNRFST-------FPKISQHDLW 1662 +V+EL + NF + G W+V+F+APWCG+C++LEP + +KD +K+ +DAT + +AS Y IRG+PTIK + G + ++G RT ++ LFS A P + + + F A+ H+++T R+SYL V +A + + + + + + +DL SSL G + RK+ + K S H +S R ST PKIS + W Sbjct: 162 DVVELTDDNFDRLVLNGDEVWMVEFFAPWCGHCKRLEPEWTAAATAVKDQTKGKVKLGAVDATVHQGLASRYGIRGFPTIKIFSKGEEPEDYEGGRTRADIVARAMDLFSANAPPPELHEIIDQDIFKSTCDDSQLCIVAVLPHILDT---GASGRNSYLD-VMRKMAEKYKKKMWGW------LWAEAGAQMDLESSLGIGGFGYPAMAAINARKMKYSLLKGSFSETGIHEFLRDLSVGRGSTASIGGGALPKISTVEAW 413 HSP 2 Score: 75.485 bits (184), Expect = 4.152e-14 Identity = 43/112 (38.39%), Postives = 64/112 (57.14%), Query Frame = -1 Query: 1342 NVIELN-SNFIE--IADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHD--GDRTVEHLILFSKRALGPAVK 1662 +VIELN SNF + + WL++FYAPWCG+C++L P + + +K + +KI +DA ++ + S Y IRG+PTIK D G RT E ++ + AL VK Sbjct: 25 DVIELNPSNFNKQVLQSDSLWLIEFYAPWCGHCQRLTPDWKKAATALKGI-VKIGAVDADQHKSLGSQYGIRGFPTIKVFGANKNKPDDYQGGRTSEAIVEGAMTALRSLVK 135
BLAST of SMED30003142 vs. Ensembl Sea Lamprey
Match: TMX3 (thioredoxin related transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:24718]) HSP 1 Score: 174.866 bits (442), Expect = 8.735e-49 Identity = 117/417 (28.06%), Postives = 201/417 (48.20%), Query Frame = -1 Query: 418 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIK--DLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIAS-MNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDAD 1659 + +LNS F E + G WLV FYAPWCG+C+KLEP++NE+ +K P+++ ++DAT + +A+ Y +RGYPTIK I G Y + G RT + +I F+ R GPA++HL + F H + FFLY+G S LK + +A + + +YF+S + +P + + H E LV+K + E S + L W+ RF TF I + ++ + K +++ I + E + +L + +A E D F + M++L M+++ P++L+F + Y+ + + + + F+++ G + +GG G K++R ++ + +P+LA + G+PL VIS +CY M T+D D Sbjct: 1 ISDLNSRFAEHKNDGVWLVDFYAPWCGHCKKLEPVWNEVAQEMKASGSPVRVGKLDATAHSGIATEYGVRGYPTIKLIKGDLSYNYKGPRTKDEIIAFANRVAGPAMRHLSTPALFAHTQSRH--DIFFLYVGGDSK-LKESFTQVALEMVVNAYFFSTPEEVLPANVHIH----------EAPAALVFKDGT-----YYEYDESDDGDLATWVRRERFPTFQAIDGYAMYAISDTGKLVVLAIVDPMST-------------EENHSRLKKLVEDVAHEYREHFHRDFQFGYVDGAEGYMSNLLMSDVEAPSLLVFNTSSQEYYLPTE-------PLLSNQDLLSFINNILDGSVPAHGGDGLGQKIKRMLFELKATITSVFRASPLLACVLFGLPLGVISTMCY---WMWTADGD 376
BLAST of SMED30003142 vs. Ensembl Sea Lamprey
Match: TMX3 (thioredoxin related transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:24718]) HSP 1 Score: 143.665 bits (361), Expect = 6.973e-38 Identity = 108/408 (26.47%), Postives = 198/408 (48.53%), Query Frame = -1 Query: 451 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNE--LEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTF---PKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCY 1659 ++EL S ++ + PWLV FYAPWC +C+KL+P++ + L H P+++ ++DA ++ +AS + RG+P+IK I G Y + G + E +I F+ R GP V L S F +A ++H +T F+Y+G S LK Y ++A L + +YFYS + +P+ + E +L +K + +F+ +E + SL+ W++ RF F I+ HDL + ++ N + + E S +F K+ F ++ +NDL M+ + VP+V++ + ++ P+ + +++ + F F+ S +G++E +GG +M+R YD T + + +L +F+ G P+ V + +CY Sbjct: 27 IVELTSTLHDLRQQEPWLVNFYAPWCSHCKKLDPVWRDVALGLHEAGSPVRVGKMDAIKHSSLASEFGARGFPSIKLIKGDLAYNYRGPHSKEKIIEFANRVSGPTVLSLSSPEAFEKAQKAH--DTCFVYVGGESP-LKEKYLEVATELIVYTYFYSATKEALPEDVILY----------ELPAVLAFKDE---TFYVFDEFE--DGSLEEWVNRERFPEFLFIDSITLHDLADTGKSLVLAVLSGTNIKHDNRLKYMV-----EEVSKNYRRNFHKQFQFG------------YTDGNIHINDLIMSVVDVPSVILVNTSSQQFFL-PEGD----LRSAKDLFT--FITSNLAGKLEAHGGNSPYFRMKRLLYDASTVISAVFQQSVLLGLFLYGTPVVVFTLICY 392
BLAST of SMED30003142 vs. Ensembl Sea Lamprey
Match: pdia4 (protein disulfide isomerase family A, member 4 [Source:ZFIN;Acc:ZDB-GENE-030131-5493]) HSP 1 Score: 74.7146 bits (182), Expect = 2.400e-14 Identity = 39/109 (35.78%), Postives = 60/109 (55.05%), Query Frame = -1 Query: 1333 ELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIK--DLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLP 1653 +LN +F +A K L++FYAPWCG+C++ Y ++ + D PI +A++DAT +A + + GYPTIK + +DGDRT + +I K P K P Sbjct: 63 DLNFDFF-VAGKDTVLLEFYAPWCGHCKEFASEYEKIAKELAENDPPIPVAKVDATVAVHLAERFSVSGYPTIKILKKGQAVDYDGDRTQDAIIAKVKEVASPDWKPPP 170 HSP 2 Score: 72.4034 bits (176), Expect = 1.293e-13 Identity = 39/108 (36.11%), Postives = 57/108 (52.78%), Query Frame = -1 Query: 1330 SNFIEIA-DKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKD--LPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPS 1644 SNF EI D LV+FYAPWCG+C+KL P Y + + PI +A++DAT ++ + + GYPT+K Y ++G R ++ GPA + L S Sbjct: 179 SNFDEIVNDADIILVEFYAPWCGHCKKLAPEYEKAAQELSKNTPPIPLAKVDATVESELGKRFGVSGYPTLKLFRKGKAYDYNGPREQYGIVSHMIEQAGPASQELKS 286 HSP 3 Score: 57.7658 bits (138), Expect = 5.824e-9 Identity = 33/87 (37.93%), Postives = 47/87 (54.02%), Query Frame = -1 Query: 1363 LVKFYAPWCGYCRKLEPIYNELEAHIKD-LPIKIARIDATRYPDVASFYQIRGYPTIKY----INGTDIYTHDGDRTVEHLILFSKR 1608 L++FYAPWCG+C+ LEPIY +L K + IA++DAT Y+ G+PTI + I DG R +E L F ++ Sbjct: 542 LIEFYAPWCGHCKSLEPIYKDLGKKYKGHKGLVIAKMDATVNDIPHDSYKAEGFPTIYFSPSGAKDRPIKFADGSRDLESLSKFIEK 628
BLAST of SMED30003142 vs. Ensembl Sea Lamprey
Match: pdia3 (protein disulfide isomerase family A, member 3 [Source:ZFIN;Acc:ZDB-GENE-031002-9]) HSP 1 Score: 73.1738 bits (178), Expect = 6.115e-14 Identity = 45/185 (24.32%), Postives = 95/185 (51.35%), Query Frame = -1 Query: 1063 LVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYT-HDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENG--TILVWKPDRKLSFHFKE 1608 LV+F+APWCG+C++L P Y + +K+ + +A++D T + + + + GYPT+K ++ + +DG RT + ++ F K+ GP+ ++E +E ++GD + + D ++ ++ F + + ++H ++ + L D + I+V++P R L+ F+E Sbjct: 46 LVEFFAPWCGHCKRLAPEYEKAATKLKNT-VALAKVDCTANTETCNKFGVSGYPTLKIFRDGELSSDYDGPRTADGIVGFLKKQAGPS------------SVELKTVEDLEKFVGDNDPSIVGFFKDASSD--AQTEFMKVASSQRDNYRFAHSNVQAVL-DKQGAEEAIVVFRPLR-LASKFEE 213 HSP 2 Score: 67.781 bits (164), Expect = 3.038e-12 Identity = 38/86 (44.19%), Postives = 54/86 (62.79%), Query Frame = -1 Query: 1363 LVKFYAPWCGYCRKLEPIYNELEAHIKDLP-IKIARIDATRYPDVASFYQIRGYPTIKY--INGTDI-YTHDGDRTVEHLILFSKR 1608 L++FYAPWCG+C+ LEP Y EL +K+ P I IA++DAT DV + Y +RG+PTI + + D ++G R V I + KR Sbjct: 394 LIEFYAPWCGHCKNLEPKYLELADKLKNDPNILIAKMDATAN-DVPAQYDVRGFPTIYFSPMGSKDSPKKYEGGREVSDFISYLKR 478
BLAST of SMED30003142 vs. Ensembl Sea Lamprey
Match: pdia6 (protein disulfide isomerase family A, member 6 [Source:ZFIN;Acc:ZDB-GENE-030131-879]) HSP 1 Score: 70.4774 bits (171), Expect = 3.804e-13 Identity = 41/112 (36.61%), Postives = 63/112 (56.25%), Query Frame = -1 Query: 1342 NVIELN-SNFIE--IADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKY--INGTDIYTHDGDRTVEHLILFSKRALGPAVK 1662 +VIEL SNF + WLV+FYAPWCG+C++L P + + +K + +K+ +DA + + S Y +RG+PTIK IN +G RT + ++ + AL VK Sbjct: 26 DVIELTASNFNREVVQSNDLWLVEFYAPWCGHCQRLIPEWKKAATALKGI-VKLGAVDADEHKGLGSTYNVRGFPTIKIFGINKNKPEDFNGGRTTQGIVDGALGALRSLVK 136 HSP 2 Score: 68.9366 bits (167), Expect = 1.219e-12 Identity = 39/130 (30.00%), Postives = 70/130 (53.85%), Query Frame = -1 Query: 1291 LNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIK---DLPIKIARIDATRYPDVASFYQIRGYPTIK-YINGTD-IYTHDGDRTVEHLI-----LFSKRALGPAVKHLPSEGRFHEAIESHLM 1650 + +N I W+V+F+APWCG+C+KLEP + +K + +K+A +DAT ++++ + IRG+PTIK + G D + G RT ++ L++ A P V + ++ ++ E H + Sbjct: 171 ITTNKITFTPSETWIVEFFAPWCGHCKKLEPEWAAAATEVKAQTNGRVKLAAVDATVNQELSNRFGIRGFPTIKVFRKGEDEPQEYQGGRTKSDIVAYALELYTDNAPAPEVVEILNQDVVKKSCEEHQL 300
BLAST of SMED30003142 vs. Ensembl Yeast
Match: PDI1 (Protein disulfide isomerase; multifunctional oxidoreductase of the ER lumen, essential for disulfide bond formation in secretory and cell-surface proteins, processing of non-native disulfide bonds; Ero1p activator; complexes with exomannosidase, Mnl1p to facilitate the recognition of misfolded glycoproteins and the trimming of glycan Man8GlcNAc2 to Man7GlcNAc2 on substrates, thereby accelerating ERAD; PDI1 has a paralog, EUG1, that arose from the whole genome duplication [Source:SGD;Acc:S000000548]) HSP 1 Score: 64.3142 bits (155), Expect = 2.872e-11 Identity = 29/91 (31.87%), Postives = 51/91 (56.04%), Query Frame = -1 Query: 1345 LVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDI---YTHDGDRTVEHLILFSKRALGPAV 1608 L +F+APWCG+C+ + P Y + + + I +A+ID T D+ + I G+P++K +D+ ++G RT E ++ F + PAV Sbjct: 53 LAEFFAPWCGHCKNMAPEYVKAAETLVEKNITLAQIDCTENQDLCMEHNIPGFPSLKIFKNSDVNNSIDYEGPRTAEAIVQFMIKQSQPAV 143 HSP 2 Score: 51.9878 bits (123), Expect = 1.806e-7 Identity = 32/87 (36.78%), Postives = 46/87 (52.87%), Query Frame = -1 Query: 1363 LVKFYAPWCGYCRKLEPIYNELEAHIKDLP--IKIARIDATRYPDVASFYQIRGYPTIKYING---TDIYTHDGDRTVEHLILFSKR 1608 LV +YAPWCG+C++L P Y EL + + IA++D T DV I GYPTI G ++ + G R+++ L F K Sbjct: 398 LVLYYAPWCGHCKRLAPTYQELADTYANATSDVLIAKLDHTEN-DVRGVV-IEGYPTIVLYPGGKKSESVVYQGSRSLDSLFDFIKE 482
BLAST of SMED30003142 vs. Ensembl Yeast
Match: EPS1 (ER protein with chaperone and co-chaperone activity; involved in retention of resident ER proteins; has a role in recognizing proteins targeted for ER-associated degradation (ERAD), member of the protein disulfide isomerase family [Source:SGD;Acc:S000001267]) HSP 1 Score: 47.7506 bits (112), Expect = 4.632e-6 Identity = 28/100 (28.00%), Postives = 49/100 (49.00%), Query Frame = -1 Query: 1363 SNFIEIADKGPWLVKFYAPWCGYCRKLEPI----YNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTH--DGDRTVEHLILFSKR 1644 +NF E KG ++ FY+P+C +C+ L P+ + E + K L I ++++ D+ I +P I+ N + + RT E LI F++R Sbjct: 40 TNFKEELSKGLHIIDFYSPYCPHCKHLAPVWMETWEEFKEESKTLNITFSQVNCIESADLCGDENIEYFPEIRLYNPSGYIKSFTETPRTKESLIAFARR 139
BLAST of SMED30003142 vs. Ensembl Nematostella
Match: EDO41581 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S406]) HSP 1 Score: 154.836 bits (390), Expect = 6.308e-43 Identity = 78/230 (33.91%), Postives = 134/230 (58.26%), Query Frame = -1 Query: 976 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSY--LKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDL 1659 V+EL+ F + ++G WLV+FYAPWCGYCRKLEP+Y E+ + I +A++DAT Y ++ Y +RG+PTIK+I G + ++GDRT + +I F+++A GPAV+ L S + + FFL + LK YD A+ + ++YFYSI++ +P+S + +N+ I V+K R + +++++ N + +W+S +F F +I++ ++ Sbjct: 27 VVELDDRFAHLKEQGSWLVEFYAPWCGYCRKLEPVYEEVAKTLHGSSINVAKLDATVYSGISREYGVRGFPTIKFIKGKKVINYEGDRTAQDIIQFAQKASGPAVRELTSGEELRKVQRERPV--FFLLVQKSGEIDTLKDHYDKAADMMLTKAYFYSIDDNQLPKS----IKINAP-------AISVFKDGRHFEYEVPDDVAASN--ISDWVSQEQFPAFIQITRTNI 241
BLAST of SMED30003142 vs. Ensembl Nematostella
Match: EDO31634 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXD7]) HSP 1 Score: 78.1814 bits (191), Expect = 2.996e-15 Identity = 56/162 (34.57%), Postives = 86/162 (53.09%), Query Frame = -1 Query: 1213 NVIEL-NSNFIE-IADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIK--DLPIKIARIDATRY-PDVASFYQIRGYPTIK-YINGTDIYTHDGDRTVEHLILFSKRALGP------AVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLR 1662 +V++L +SNF +A K LV+F+APWCG+C++L P Y +K D P+ +A++D T D S Y + GYPT+K + NG +DG R +I + K+ GP +V HL E + +A ES+++ F D LK + AN +R Sbjct: 19 DVLDLGDSNFKSGVAGKDIMLVEFFAPWCGHCKRLAPEYETAAEALKKNDPPVPLAKVDCTEAGKDTCSKYGVSGYPTLKIFRNGEMSKDYDGPRDSSGIIRYMKKQAGPSSVEIKSVDHL--EKKLDDA-ESNVVVGFL----DGDDDLKNAFMRTANEMR 173 HSP 2 Score: 68.1662 bits (165), Expect = 3.801e-12 Identity = 39/104 (37.50%), Postives = 60/104 (57.69%), Query Frame = -1 Query: 1363 IELNSNFIEIADK--GPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLP-IKIARIDATRYPDVASFYQIRGYPTIKYI---NGTDIYTHDGDRTVEHLILFSKR 1656 + + NF EI + L++FYAPWCG+C+ LEP YNEL ++D+ I IA++DAT D + ++G+PTI + N + ++G R V + F KR Sbjct: 365 VVVGENFKEIVNDPTKDVLIEFYAPWCGHCKSLEPKYNELGEKLQDVKDIVIAKMDATAN-DAPPNFSVQGFPTIYWAPANNKENPEKYEGGREVSDFVDFIKR 467
BLAST of SMED30003142 vs. Ensembl Nematostella
Match: EDO41377 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4E7]) HSP 1 Score: 75.8702 bits (185), Expect = 7.568e-15 Identity = 34/81 (41.98%), Postives = 51/81 (62.96%), Query Frame = -1 Query: 1372 LVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKI-ARIDATRYPDVASFYQIRGYPTIK-YINGTDIYTHDGDRTVEHLILF 1608 LV FYAPWCG+C+ +P Y + KD P ++ A++D T++ DV ++ GYPT++ Y+ G + +DGDR E LI F Sbjct: 260 LVMFYAPWCGHCKNAKPKYEKAAETFKDQPNRVFAKLDCTKFGDVCDKEEVNGYPTLRYYLYGKFVVEYDGDRVTEDLISF 340 HSP 2 Score: 69.707 bits (169), Expect = 7.849e-13 Identity = 33/86 (38.37%), Postives = 53/86 (61.63%), Query Frame = -1 Query: 1360 LVKFYAPWCGYCRKLEPIYNELEA--HIKDLPIKIARIDATRYPDVASFYQIRGYPTIK-YINGTDIYTHDGDRTVEHLILFSKRA 1608 LV ++APWCG+C +++P Y + H +D +A +D T++ DVA + GYPT+K Y NG ++GDR+ + L+LF + A Sbjct: 140 LVMYFAPWCGHCNEMKPNYYKAAQVLHDEDANCNLAAVDCTKHKDVAKKVALAGYPTVKLYKNGKVAKEYEGDRSEKDLVLFMRTA 225 HSP 3 Score: 48.9062 bits (115), Expect = 3.350e-6 Identity = 23/73 (31.51%), Postives = 42/73 (57.53%), Query Frame = -1 Query: 1372 CGYCRKLEPIYNELEAHI-KDLPIKIARIDATRYPDVASFYQIRGYPTIKYI-NGTDIYTHDGDRTVEHLILF 1584 C +C+K++P++ + + KD+ +A +D T + + I+GYPT++YI G + + G RT E L+ F Sbjct: 26 CPHCQKMKPVFEKAAKQLGKDVKGALAAVDCTESKNTCNQRDIKGYPTLQYIREGEFQFKYTGRRTAEALVSF 98
BLAST of SMED30003142 vs. Ensembl Nematostella
Match: EDO36830 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHH5]) HSP 1 Score: 76.6406 bits (187), Expect = 9.652e-15 Identity = 34/95 (35.79%), Postives = 53/95 (55.79%), Query Frame = -1 Query: 1330 LVKFYAPWCGYCRKLEPIYNELEAHIKDLP--IKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPS 1608 LV+FYAPWCG+C+ L P Y + +K IK+A++DAT + +Q++GYPTIK+ + G RT ++ + + GP K L + Sbjct: 45 LVEFYAPWCGHCKALAPEYAKAAGQLKSEKSEIKLAKVDATAETKLGEKFQVQGYPTIKFFKDGKPSEYAGGRTAPEIVSWLNKKTGPPAKDLAT 139 HSP 2 Score: 59.6918 bits (143), Expect = 2.204e-9 Identity = 38/114 (33.33%), Postives = 63/114 (55.26%), Query Frame = -1 Query: 1321 NSNFIEIA---DKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKD-LPIKIARIDATRYPDVASFYQIRGYPTIKYI-NGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGR 1647 NF E+A DK + V+FYAPWCG+C++L PI+++L KD I +A++D+T + ++ +PTIKY + ++G RT++ + F + G A +EG Sbjct: 371 GKNFDEVARNKDKNVF-VEFYAPWCGHCKQLAPIWDQLGEKYKDHADIVVAKMDST--ANEVEGVKVHSFPTIKYFPKEGEAVDYNGGRTLDDFVKFLESG-GKAGNEPAAEGE 480
BLAST of SMED30003142 vs. Ensembl Nematostella
Match: EDO33843 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR22]) HSP 1 Score: 70.0922 bits (170), Expect = 2.561e-14 Identity = 41/101 (40.59%), Postives = 57/101 (56.44%), Query Frame = -1 Query: 1372 IELNSNFIEIAD--KGPWLVKFYAPWCGYCRKLEPIYNELEAHIK-DLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTH---DGDRTVEHLILF 1656 + + F EI + K L++FYAPWCG+C+ LEP + +L H + D I IA+IDAT DV S Y + G+PTI + D DG R ++ LI F Sbjct: 31 VVVGKTFDEIVNDPKKDVLIEFYAPWCGHCKALEPTFKKLGKHFRNDKNIVIAKIDATAN-DVPSTYAVEGFPTIYFATSKDKKNPIKFDGGRELKDLIKF 130
BLAST of SMED30003142 vs. Ensembl Medaka
Match: TMX3 (thioredoxin related transmembrane protein 3 [Source:NCBI gene;Acc:101165851]) HSP 1 Score: 191.045 bits (484), Expect = 1.605e-53 Identity = 126/418 (30.14%), Postives = 217/418 (51.91%), Query Frame = -1 Query: 415 VIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDL--PIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIAS-MNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADN 1659 V +L+S F + WLV FYAPWCGYC+KLEPI++E+ A ++ P+++ ++DAT Y +AS + +RGYPTIK + Y + G RT + ++ F+ R GPAV+ LPS F ++ H + F+Y+G S LK Y+D A+ L + +YF+S +P+ S+S E ++V+K ++ E + SL +W++ RF + +I L+EL K + I + + + ES +K + +++A E + + N +F D + +N L M + VP+V+I N ++ S + M+ + +F+ D L+ G + YGG GF +++R +D + ++ ++P+L F+ G+PL VIS +CY IC ++ D + Sbjct: 44 VEDLDSTFKDTRVNDIWLVDFYAPWCGYCKKLEPIWDEVGAELRSSGSPVRVGKMDATAYSGMASEFGVRGYPTIKLLKADLAYNYKGPRTKDDIVEFANRVAGPAVRALPSTQMFEHMMKRH--DVLFVYVGGDSP-LKEKYNDAASELIVYTYFFSASEDAVPE----------SISMPELPAVVVFKDGDYFTYDEYE-----DGSLSSWVNRERFQGYLQIDGFTLYELGETGKLVAIAVIDEKDAT-----------EESGRLK--TLMQRVAKE-YREHFNRVFQFGHMDGSDYINSLIMGEVKVPSVIILNTSNEQYFLS--SEPIETMEQL-VQFISDVLN----GSAQAYGGDGFIQRIKRVAFDARSTIMSVFRSSPLLGCFLFGLPLGVISLMCYGICTAESDDGSD 422
BLAST of SMED30003142 vs. Ensembl Medaka
Match: ENSORLT00000009634.2 (protein disulfide-isomerase TMX3-like [Source:NCBI gene;Acc:101157158]) HSP 1 Score: 140.969 bits (354), Expect = 6.309e-36 Identity = 118/444 (26.58%), Postives = 208/444 (46.85%), Query Frame = -1 Query: 379 VIELNSNFIEIADKGP---WLVKFYAPWCGYCRKLEPIYNELEAHIKDLP--IKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERE--SSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIAS--MNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAID-EKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADNRRIEAR-------QQKKIR 1659 V EL+ +F+E KG WL++FYAPWC +C++L+P+++E+ + ++ L +++ + DAT +A +++R YP I + Y + G RT E ++ F+ R GP V+ L S F A+ H F+Y+G +S LK + +A L + ++F+S +P+S LD + I+V+K L++ +E S + L+ WI+ RF F I + L+ + S + ER S +++ +++A E + E FF++ A +N M + VP+++ N YQ ++ E+ + DFL G IE GG GF ++QR Y+ +I P++ F+ G PL++ +F C+ +CC + + D+ A Q+KKI+ Sbjct: 24 VEELDDSFMET--KGSDEIWLIEFYAPWCSFCKQLDPVWHEIGSELRSLGSMVQVGKSDATVSTGLAKEFRVRTYPAILMLKKNTKYNYAGPRTKEGIMDFANRMEGPVVRSLSSPQLFQHAMSHH--NVMFVYVG-ATSELKGNFTTVAEELIVHTHFFSTTRDVLPKSV--SLDYLPA--------IVVFKDRTYLTY---DEES--DGDLKAWINRERFLNFQHIDSYTLY---------------AMGESGKLVLLALVEERHLCSKSLRYKHLVERVAEE--HKETYSRFFLFGFMAAGDYINGFVMGEVTVPSLIAVNLSN--------DGYYQPAGPVETERQLLDFLDGVLDGTIEMKGGNGFSQRVQRVIYETKATVIPVFRDAPLIGCFLAGFPLAIGAFFCF-LCCRNQTIPDDDEDTAALLASSVPQRKKIK 421
BLAST of SMED30003142 vs. Ensembl Medaka
Match: pdia3 (protein disulfide isomerase family A member 3 [Source:NCBI gene;Acc:101164975]) HSP 1 Score: 79.337 bits (194), Expect = 3.900e-15 Identity = 53/217 (24.42%), Postives = 104/217 (47.93%), Query Frame = -1 Query: 988 LVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIK-YINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDT---ENGTILVWKPDRKLSFHFKE------EISSLNHSLQNWISFNRFSTFPKIS 1608 LV+F+APWCG+C++L P Y +K + + + ++D T ++ S Y + GYPT+K + +G + +DG R+ + ++ F K+ GPA L ++ F + +IGD+ + + + D + S ++ F + ++H + + L E G +L P +L+ F+E E ++ ++ +I N F P ++ Sbjct: 38 LVEFFAPWCGHCKRLAPEYEAAATRLKGI-VPLVKVDCTANSNICSKYGVSGYPTLKIFRDGEESGPYDGPRSADGIVSFLKKQAGPASVELKTDADFEK------------FIGDQDASVVGFFADQSTS---QAEFLKAASALRDDYRFAHTNSEALLKSNGIDEEGVVLFRPP--RLNNKFEENSVKFTEDKFTSNKIKKFIQENIFGICPHMT 236 HSP 2 Score: 70.4774 bits (171), Expect = 1.971e-12 Identity = 37/86 (43.02%), Postives = 53/86 (61.63%), Query Frame = -1 Query: 1363 LVKFYAPWCGYCRKLEPIYNELEAHIKDLP-IKIARIDATRYPDVASFYQIRGYPTIKYING---TDIYTHDGDRTVEHLILFSKR 1608 L++FYAPWCG+C+ LEP YNEL + + P + IA++DAT DV S Y++ G+PTI + T ++G R V I + KR Sbjct: 386 LIEFYAPWCGHCKNLEPKYNELGEKLANDPNVVIAKMDATAN-DVPSPYEVSGFPTIYFSPAGRKTSPKKYEGGREVSDFISYLKR 470
BLAST of SMED30003142 vs. Ensembl Medaka
Match: pdia2 (protein disulfide-isomerase [Source:NCBI gene;Acc:101164281]) HSP 1 Score: 79.337 bits (194), Expect = 4.043e-15 Identity = 57/204 (27.94%), Postives = 97/204 (47.55%), Query Frame = -1 Query: 1015 LVKFYAPWCGYCRKLEPIYNELEAHIKD--LPIKIARIDATRYPDVASFYQIRGYPTIK-YING--TDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWK-PDRKLSFHFKEEISSLNHSLQNWISFN 1608 +V+FYAPWCGYCR+ EPIY E +K+ +++A++DA ++A + + +PT+K ++NG + + G RT ++ + KR GP L S E I +H + + + + S AV+ ++A L + + P+ + + T N +L K D + F EE H+L N+I N Sbjct: 90 MVEFYAPWCGYCRRFEPIYAEAAGMLKEEGSEMRLAKVDAIEEKELAEEFNVDSFPTVKLFMNGDRKEPIEYTGKRTPSGIVQWLKRRSGPGAADLNSADSAAEFINTHNV-SVVGFFDNLESEAAAVFKEVAFDLTDVEFAVTAS----PEVFKEY-------EVTANKVVLFKKFDDGRADFELSEEDKLDKHNLTNFIKEN 281 HSP 2 Score: 59.3066 bits (142), Expect = 8.526e-9 Identity = 32/81 (39.51%), Postives = 49/81 (60.49%), Query Frame = -1 Query: 1372 VKFYAPWCGYCRKLEPIYNEL-EAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTD--IYTHDGDRTVEHLILF 1605 V+FYAPWCG+C++L PI+ +L E + I IA++DAT + I G+PT+KY D + ++ G+R +E L F Sbjct: 422 VEFYAPWCGHCKELAPIWEQLGEIYADHDDIIIAKMDAT--ANEVESVAIDGFPTLKYFPAGDKEVISYTGNRDLETLSKF 500
BLAST of SMED30003142 vs. Ensembl Medaka
Match: pdia2 (protein disulfide-isomerase [Source:NCBI gene;Acc:101164281]) HSP 1 Score: 78.9518 bits (193), Expect = 4.809e-15 Identity = 57/204 (27.94%), Postives = 97/204 (47.55%), Query Frame = -1 Query: 1015 LVKFYAPWCGYCRKLEPIYNELEAHIKD--LPIKIARIDATRYPDVASFYQIRGYPTIK-YING--TDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWK-PDRKLSFHFKEEISSLNHSLQNWISFN 1608 +V+FYAPWCGYCR+ EPIY E +K+ +++A++DA ++A + + +PT+K ++NG + + G RT ++ + KR GP L S E I +H + + + + S AV+ ++A L + + P+ + + T N +L K D + F EE H+L N+I N Sbjct: 86 MVEFYAPWCGYCRRFEPIYAEAAGMLKEEGSEMRLAKVDAIEEKELAEEFNVDSFPTVKLFMNGDRKEPIEYTGKRTPSGIVQWLKRRSGPGAADLNSADSAAEFINTHNV-SVVGFFDNLESEAAAVFKEVAFDLTDVEFAVTAS----PEVFKEY-------EVTANKVVLFKKFDDGRADFELSEEDKLDKHNLTNFIKEN 277 HSP 2 Score: 61.2326 bits (147), Expect = 1.990e-9 Identity = 34/80 (42.50%), Postives = 49/80 (61.25%), Query Frame = -1 Query: 1372 LVKFYAPWCGYCRKLEPIYNEL-EAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILF 1608 V+FYAPWCG+C++L PI+ +L E + I IA++DAT +V S I G+PT+KY D + G+R +E L F Sbjct: 431 FVEFYAPWCGHCKELAPIWEQLGEIYADHDDIIIAKMDATAN-EVESV-AIDGFPTLKYFPAGDKEVYTGNRDLETLSKF 508
BLAST of SMED30003142 vs. Planmine SMEST
Match: SMESG000029028.1 (SMESG000029028.1) HSP 1 Score: 861.677 bits (2225), Expect = 0.000e+0 Identity = 450/453 (99.34%), Postives = 452/453 (99.78%), Query Frame = -1 Query: 304 NVIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSHLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPERESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVHDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADNRRIEARQQKKIRIPLYEVALKSSEELNIKSDGDKKNE 1662 NVIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYS+LDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWELEILKKSLIILICNSSLLSDINSNPSDNPE+ESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFV DFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADNRRIEARQQKKIRIPLYEVALKSSEELNIKSDGDKKNE Sbjct: 21 NVIELNSNFIEIADKGPWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANSLRLRSYFYSIENQFIPQSYYSYLDLNSSLSDTENGTILVWKPDRKLSFHFKEEISSLNHSLQNWISFNRFSTFPKISQHDLWELEILKKSLIILICNSSLLSDINSNPSDNPEQESSTMKLFSFAKKLAFESFNDEQNDLFFVWSTDIASMNDLAMTNLIVPNVLIFQPWNHTIYIHPDSNNYQKMKAIDEKFVLDFLHSFQSGEIEGYGGVGFRAKMQRAGYDFITGLIEFVSTTPILAMFIIGVPLSVISFLCYAICCMDTSDADNRRIEARQQKKIRIPLYEVALKSSEELNIKSDGDKKNE 473
BLAST of SMED30003142 vs. Planmine SMEST
Match: SMESG000023147.1 (SMESG000023147.1) HSP 1 Score: 91.6633 bits (226), Expect = 2.902e-19 Identity = 50/146 (34.25%), Postives = 82/146 (56.16%), Query Frame = -1 Query: 1219 NSNFIEIADKGPW-LVKFYAPWCGYCRKLEPIYNELEAHIKDLP--IKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHEAIESHLMETFFLYIGDRSSYLKAVYDDLANS 1647 NSNF E+ +K + LV+FYAPWCG+C+ L P Y +K+ IK+A++DAT D+AS ++I+GYPT+K+ + + G RT + +I + ++ GP L S IES + + D++S ++ +A+S Sbjct: 31 NSNFNEVIEKNKYVLVEFYAPWCGHCKALAPEYASAAEKLKEKNSIIKLAKVDATVENDLASKFKIQGYPTLKFFKDGKVMDYGGGRTADTIISWLEKKTGPPAATLKSVEEAKALIESKDV-VVVGFFKDQASAAAKAFESVADS 175 HSP 2 Score: 62.3882 bits (150), Expect = 5.280e-10 Identity = 37/98 (37.76%), Postives = 59/98 (60.20%), Query Frame = -1 Query: 1372 LNSNFIEIA-DKGPWL-VKFYAPWCGYCRKLEPIYNELEAHIKD-LPIKIARIDATRYPDVASFYQIRGYPTIKYI--NGTDIYTHDGDRTVEHLILF 1650 + NF +A DK + V+FYAPWCG+C++L PI+++L KD I IA++D+T + +I+ +PTIKY + ++ +GDRT+E F Sbjct: 371 VGKNFDSVARDKSKAVFVEFYAPWCGHCKQLAPIWDQLGETYKDNTDIVIAKMDST--ANEVEGVRIQSFPTIKYFPKDSDEMVDFEGDRTLETFKKF 466
BLAST of SMED30003142 vs. Planmine SMEST
Match: SMESG000017020.1 (SMESG000017020.1) HSP 1 Score: 80.4925 bits (197), Expect = 8.161e-16 Identity = 43/136 (31.62%), Postives = 78/136 (57.35%), Query Frame = -1 Query: 1291 NVIEL-NSNFIEIADKG--PWLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKY----INGTDIYTHDGDRTVEHLILFSKRAL-----GPAVKHLPSEGRFHEAIESHLM 1662 +V+EL +SNF E+ K PWLV+F+APWCG+C+ L+P +++ + ++ +K+ +DAT + AS Y ++GYPTIK+ + D +DG R+ ++ ++ + P +K + ++ A E H + Sbjct: 161 DVVELTDSNFDEMVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRG-KVKLGALDATVHTATASRYGVQGYPTIKFFPAGVKSGDSQDYDGGRSSSDIVRWASDKVVEQLPAPEIKEILNQEILKSACEDHQL 295 HSP 2 Score: 67.0106 bits (162), Expect = 1.680e-11 Identity = 34/99 (34.34%), Postives = 56/99 (56.57%), Query Frame = -1 Query: 1378 NVIELN-SNFIEIADKGP-WLVKFYAPWCGYCRKLEPIYNELEAHIKDLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIYTHD--GDRTVEHLI 1662 +V+EL SNF ++ + W V+FYAPWCG+C+ L P + + +K + +K+ +D +Y + Y I+G+PTIK + D GDRT ++ Sbjct: 25 DVVELTPSNFDDMKNSDSLWFVEFYAPWCGHCQSLAPEWKKAATALKGV-VKVGAVDMDKYSSLGQPYGIQGFPTIKIFGKSKHSPKDYQGDRTAGSIV 122
BLAST of SMED30003142 vs. Planmine SMEST
Match: SMESG000041085.1 (SMESG000041085.1) HSP 1 Score: 78.9518 bits (193), Expect = 3.114e-15 Identity = 38/102 (37.25%), Postives = 59/102 (57.84%), Query Frame = -1 Query: 1312 LVKFYAPWCGYCRKLEPIYNELEAHIK--DLPIKIARIDATRYPDVASFYQIRGYPTIK-YINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHE 1608 LV+FYAPWCG+C+KL P Y +K D PI IA++D T + + GYPT+K + NG + + G+R+ + +I + GP+ K L +E F++ Sbjct: 38 LVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNK 139 HSP 2 Score: 61.6178 bits (148), Expect = 8.763e-10 Identity = 33/100 (33.00%), Postives = 55/100 (55.00%), Query Frame = -1 Query: 1321 LVKFYAPWCGYCRKLEPIYNELEAHIK-DLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIY---THDGDRTVEHLILFSKRALGPAVKHLPSEGR 1608 L++FYAPWCG+C+ L P Y EL + + I IA++DAT DV S Y++ G+PTI + + ++ R V+ ++ + +K+ +GR Sbjct: 386 LIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGR 484
BLAST of SMED30003142 vs. Planmine SMEST
Match: SMESG000041085.1 (SMESG000041085.1) HSP 1 Score: 78.9518 bits (193), Expect = 3.200e-15 Identity = 38/102 (37.25%), Postives = 59/102 (57.84%), Query Frame = -1 Query: 1312 LVKFYAPWCGYCRKLEPIYNELEAHIK--DLPIKIARIDATRYPDVASFYQIRGYPTIK-YINGTDIYTHDGDRTVEHLILFSKRALGPAVKHLPSEGRFHE 1608 LV+FYAPWCG+C+KL P Y +K D PI IA++D T + + GYPT+K + NG + + G+R+ + +I + GP+ K L +E F++ Sbjct: 24 LVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNK 125 HSP 2 Score: 61.6178 bits (148), Expect = 9.876e-10 Identity = 33/100 (33.00%), Postives = 55/100 (55.00%), Query Frame = -1 Query: 1321 LVKFYAPWCGYCRKLEPIYNELEAHIK-DLPIKIARIDATRYPDVASFYQIRGYPTIKYINGTDIY---THDGDRTVEHLILFSKRALGPAVKHLPSEGR 1608 L++FYAPWCG+C+ L P Y EL + + I IA++DAT DV S Y++ G+PTI + + ++ R V+ ++ + +K+ +GR Sbjct: 372 LIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGR 470 The following BLAST results are available for this feature:
BLAST of SMED30003142 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of SMED30003142 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of SMED30003142 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of SMED30003142 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of SMED30003142 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of SMED30003142 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of SMED30003142 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of SMED30003142 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of SMED30003142 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of SMED30003142 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of SMED30003142 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of SMED30003142 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of SMED30003142 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of SMED30003142 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30003142 ID=SMED30003142|Name=SMED30003142|organism=Schmidtea mediterranea sexual|type=transcript|length=1884bpback to top protein sequence of SMED30003142-orf-1 >SMED30003142-orf-1 ID=SMED30003142-orf-1|Name=SMED30003142-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=474bp MILFFKIFIYIISISIPAFSNVIELNSNFIEIADKGPWLVKFYAPWCGYCback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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