HMG box domain-containing protein

Overview
NameHMG box domain-containing protein
Smed IDSMED30003094
Length (bp)5665
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of HMG box domain-containing protein (SMED30003094) t-SNE clustered cells

Violin plots show distribution of expression levels for HMG box domain-containing protein (SMED30003094) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of HMG box domain-containing protein (SMED30003094) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for HMG box domain-containing protein (SMED30003094) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30003094

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30003094SMESG000017540.1 SMESG000070603.1 SMESG000070576.1 SMESG000017600.1 SMESG000017572.1 SMESG000017558.1 SMESG000017557.1 SMESG000017556.1 SMESG000017543.1 SMESG000017541.1 dd_Smed_v4_4601_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30003094SMESG000017540.1 SMESG000070603.1 SMESG000070576.1 SMESG000017600.1 SMESG000017572.1 SMESG000017558.1 SMESG000017557.1 SMESG000017556.1 SMESG000017543.1 SMESG000017541.1 dd_Smed_v4_4601_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30003094SMESG000017540.1 SMESG000070603.1 SMESG000070576.1 SMESG000017600.1 SMESG000017572.1 SMESG000017558.1 SMESG000017557.1 SMESG000017556.1 SMESG000017543.1 SMESG000017541.1 dd_Smed_v4_4601_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30003094SMESG000017540.1 SMESG000070603.1 SMESG000070576.1 SMESG000017600.1 SMESG000017572.1 SMESG000017558.1 SMESG000017557.1 SMESG000017556.1 SMESG000017543.1 SMESG000017541.1 dd_Smed_v4_4601_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30003094SMESG000017540.1 SMESG000070603.1 SMESG000070576.1 SMESG000017600.1 SMESG000017572.1 SMESG000017558.1 SMESG000017557.1 SMESG000017556.1 SMESG000017543.1 SMESG000017541.1 dd_Smed_v4_4601_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30003094SMESG000017540.1 SMESG000070603.1 SMESG000070576.1 SMESG000017600.1 SMESG000017572.1 SMESG000017558.1 SMESG000017557.1 SMESG000017556.1 SMESG000017543.1 SMESG000017541.1 dd_Smed_v4_4601_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Human
Match: CIC (capicua transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:14214])

HSP 1 Score: 103.605 bits (257), Expect = 3.889e-21
Identity = 46/78 (58.97%), Postives = 59/78 (75.64%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRS 2780
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW +    +S
Sbjct: 1109 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKS 1186

HSP 2 Score: 97.8265 bits (242), Expect = 2.301e-19
Identity = 48/88 (54.55%), Postives = 62/88 (70.45%), Query Frame = 3 
Query: 1647 SQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITPGPSFNGHPSLFLSRDSNAGVD 1910
            +Q+ Y+KGDVV TP+G+RKKFNGKQWRRLCS++ C KESQRRG+CSRHLSMR KE+     +     GP   G P+   +R+ +   D
Sbjct:  477 AQQKYKKGDVVCTPSGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADS-----GPGGAGRPAAVAAREGSTEFD 559

HSP 3 Score: 59.6918 bits (143), Expect = 7.588e-8
Identity = 65/229 (28.38%), Postives = 103/229 (44.98%), Query Frame = 3 
Query: 4458 RKLDEDTENVLAEVDFQRKFIDLPQFNPESIN-----DNVAQSPRVI---------NIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLL--TPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            +K  +  + VL+EVDF+ +F +LP+F PE +       ++A SPR I         N  +L + PE    D     R ++R     + + EPN   PKSA              +IF                             F   G +A  +L       +  S  ++ L+ RR  V++LF+++   FP+A+  + +Q ++A++FPS   L+ KIREVRQKIMQ
Sbjct: 2246 KKTFDSVDKVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPE----DPTSPKRKMRRR---SSCSSEPN--TPKSAKCE----------GDIF----------------------------TFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDH-GFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQ 2426
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Human
Match: CIC (capicua transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:14214])

HSP 1 Score: 101.293 bits (251), Expect = 1.529e-20
Identity = 46/78 (58.97%), Postives = 59/78 (75.64%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRS 2780
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW +    +S
Sbjct:  200 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKS 277

HSP 2 Score: 59.6918 bits (143), Expect = 6.955e-8
Identity = 66/231 (28.57%), Postives = 102/231 (44.16%), Query Frame = 3 
Query: 4452 FKRKLDEDTENVLAEVDFQRKFIDLPQFNPESIN-----DNVAQSPRVI---------NIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLL--TPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
             K+  D     VL+EVDF+ +F +LP+F PE +       ++A SPR I         N  +L + PE    D     R ++R     + + EPN   PKSA              +IF                             F   G +A  +L       +  S  ++ L+ RR  V++LF+++   FP+A+  + +Q ++A++FPS   L+ KIREVRQKIMQ
Sbjct: 1338 LKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPE----DPTSPKRKMRRR---SSCSSEPN--TPKSAKCE----------GDIF----------------------------TFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDH-GFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQ 1520
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Human
Match: CIC (capicua transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:14214])

HSP 1 Score: 101.293 bits (251), Expect = 1.554e-20
Identity = 46/78 (58.97%), Postives = 59/78 (75.64%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRS 2780
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW +    +S
Sbjct:  200 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKS 277

HSP 2 Score: 59.6918 bits (143), Expect = 6.953e-8
Identity = 66/231 (28.57%), Postives = 102/231 (44.16%), Query Frame = 3 
Query: 4452 FKRKLDEDTENVLAEVDFQRKFIDLPQFNPESIN-----DNVAQSPRVI---------NIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLL--TPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
             K+  D     VL+EVDF+ +F +LP+F PE +       ++A SPR I         N  +L + PE    D     R ++R     + + EPN   PKSA              +IF                             F   G +A  +L       +  S  ++ L+ RR  V++LF+++   FP+A+  + +Q ++A++FPS   L+ KIREVRQKIMQ
Sbjct: 1336 LKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPE----DPTSPKRKMRRR---SSCSSEPN--TPKSAKCE----------GDIF----------------------------TFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDH-GFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQ 1518
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Human
Match: BBX (BBX high mobility group box domain containing [Source:HGNC Symbol;Acc:HGNC:14422])

HSP 1 Score: 78.9518 bits (193), Expect = 6.265e-16
Identity = 41/112 (36.61%), Postives = 59/112 (52.68%), Query Frame = 3 
Query: 2421 DIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            D V+    D  +QD    E +          SP Q      R RRPMNAF++F  RHR  V +++P  DNR  ++IL +WW  +   EK+ Y  +A++ KDA  +  PG+KW
Sbjct:   53 DKVQLLGADGLEQDVGETEDDE---------SPEQ------RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKW 149
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Human
Match: BBX (BBX high mobility group box domain containing [Source:HGNC Symbol;Acc:HGNC:14422])

HSP 1 Score: 77.411 bits (189), Expect = 1.314e-15
Identity = 41/112 (36.61%), Postives = 59/112 (52.68%), Query Frame = 3 
Query: 2421 DIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            D V+    D  +QD    E +          SP Q      R RRPMNAF++F  RHR  V +++P  DNR  ++IL +WW  +   EK+ Y  +A++ KDA  +  PG+KW
Sbjct:   53 DKVQLLGADGLEQDVGETEDD---------ESPEQ------RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKW 149
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Celegans
Match: gei-3 (GEX Interacting protein [Source:UniProtKB/TrEMBL;Acc:Q0G834])

HSP 1 Score: 120.939 bits (302), Expect = 6.402e-27
Identity = 48/74 (64.86%), Postives = 59/74 (79.73%), Query Frame = 3 
Query: 2541 PRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSS 2762
            P +RRPMNAFMIFS RHR  VH+Q PNKDNR VS+ILGEWWY ++  +K  Y KLA Q+K+AHF+ +P WKWS+
Sbjct:  841 PHVRRPMNAFMIFSKRHRPLVHQQYPNKDNRTVSKILGEWWYSLAADQKAEYHKLATQVKEAHFKAHPDWKWST 914

HSP 2 Score: 97.4413 bits (241), Expect = 8.703e-20
Identity = 46/90 (51.11%), Postives = 61/90 (67.78%), Query Frame = 3 
Query: 1650 QKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITPGPS----FNGHPSLFLSRDSNAGV 1907
            Q+ ++KG++V T  G+RKKFNGKQWRRLCSKE C KESQRRG+CSRHLS++ K         G +PG S    F+  P++FL   + + V
Sbjct:  443 QQRFKKGEIVTTQCGIRKKFNGKQWRRLCSKEGCNKESQRRGYCSRHLSLKSKPPHGHHMERG-SPGSSKSDIFHPEPTVFLPSSTASRV 531

HSP 3 Score: 65.855 bits (159), Expect = 3.652e-10
Identity = 64/218 (29.36%), Postives = 95/218 (43.58%), Query Frame = 3 
Query: 4440 ASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIM 5093
            ++ LFKR  DE  + +LA V F  KF  LP+F P+  N+ +  SP         N+P                  TPG                            +IFFG++F       S  + T   A TP++P  + +G + +P+     S+     KK+LE RR  V   F +++ LFP   T++ +Q+ H  VFP+   L  KIREVRQ+ M
Sbjct: 1200 SAKLFKRN-DEQMDKLLARVGFTEKFAQLPEFTPKIYNE-IPASP---------NLPTPFK--------------TPGQDQ-------------------------SIFFGANFNPDQQFLSRDNVTPQSACTPMTP--MMSG-QTTPMFGERSSI-----KKLLEERRRLVAT-FLDDQGLFPNNHTINEFQELHKEVFPTRNALILKIREVRQRRM 1358
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Celegans
Match: gei-3 (GEX Interacting protein [Source:UniProtKB/TrEMBL;Acc:Q0G834])

HSP 1 Score: 118.627 bits (296), Expect = 9.050e-27
Identity = 48/74 (64.86%), Postives = 59/74 (79.73%), Query Frame = 3 
Query: 2541 PRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSS 2762
            P +RRPMNAFMIFS RHR  VH+Q PNKDNR VS+ILGEWWY ++  +K  Y KLA Q+K+AHF+ +P WKWS+
Sbjct:   76 PHVRRPMNAFMIFSKRHRPLVHQQYPNKDNRTVSKILGEWWYSLAADQKAEYHKLATQVKEAHFKAHPDWKWST 149

HSP 2 Score: 65.4698 bits (158), Expect = 2.864e-10
Identity = 64/218 (29.36%), Postives = 95/218 (43.58%), Query Frame = 3 
Query: 4440 ASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIM 5093
            ++ LFKR  DE  + +LA V F  KF  LP+F P+ I + +  SP         N+P                  TPG                            +IFFG++F       S  + T   A TP++P  + +G + +P+     S+     KK+LE RR  V   F +++ LFP   T++ +Q+ H  VFP+   L  KIREVRQ+ M
Sbjct:  435 SAKLFKRN-DEQMDKLLARVGFTEKFAQLPEFTPK-IYNEIPASP---------NLPTPFK--------------TPGQDQ-------------------------SIFFGANFNPDQQFLSRDNVTPQSACTPMTP--MMSG-QTTPMFGERSSI-----KKLLEERRRLVAT-FLDDQGLFPNNHTINEFQELHKEVFPTRNALILKIREVRQRRM 593
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Celegans
Match: sox-4 (SOX (Mammalian SRY box) family [Source:UniProtKB/TrEMBL;Acc:Q17922])

HSP 1 Score: 66.6254 bits (161), Expect = 2.535e-11
Identity = 34/104 (32.69%), Postives = 59/104 (56.73%), Query Frame = 3 
Query: 2541 PRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGR-SKFSNSYEDTENKEVGKQVDLGNN 2849
            PRI+RPMNAFM++S + R ++        N  +S++LG  W +M   EK P+ + A+QL++ HF  +P + +   +  R  K + S +     E+ K V++ N+
Sbjct:  119 PRIKRPMNAFMVWSQQRRQQIAATGQKFHNSDISKMLGAEWRKMEEHEKVPFVERAKQLREEHFNAHPDYVYRPRRRKRVEKSAGSVDSNSADEITKPVNVYNS 222
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Celegans
Match: sox-4 (SOX (Mammalian SRY box) family [Source:UniProtKB/TrEMBL;Acc:Q17922])

HSP 1 Score: 65.4698 bits (158), Expect = 3.509e-11
Identity = 34/103 (33.01%), Postives = 58/103 (56.31%), Query Frame = 3 
Query: 2541 PRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGR-SKFSNSYEDTENKEVGKQVDLGN 2846
            PRI+RPMNAFM++S + R ++        N  +S++LG  W +M   EK P+ + A+QL++ HF  +P + +   +  R  K + S +     E+ K V++ N
Sbjct:   83 PRIKRPMNAFMVWSQQRRQQIAATGQKFHNSDISKMLGAEWRKMEEHEKVPFVERAKQLREEHFNAHPDYVYRPRRRKRVEKSAGSVDSNSADEITKPVNVYN 185
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Celegans
Match: gei-3 (GEX Interacting protein [Source:UniProtKB/TrEMBL;Acc:Q0G834])

HSP 1 Score: 64.6994 bits (156), Expect = 1.300e-10
Identity = 64/218 (29.36%), Postives = 95/218 (43.58%), Query Frame = 3 
Query: 4440 ASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIM 5093
            ++ LFKR  DE  + +LA V F  KF  LP+F P+  N+ +  SP         N+P                  TPG                            +IFFG++F       S  + T   A TP++P  + +G + +P+     S+     KK+LE RR  V   F +++ LFP   T++ +Q+ H  VFP+   L  KIREVRQ+ M
Sbjct:   86 SAKLFKRN-DEQMDKLLARVGFTEKFAQLPEFTPKIYNE-IPASP---------NLPTPFK--------------TPGQDQ-------------------------SIFFGANFNPDQQFLSRDNVTPQSACTPMTP--MMSG-QTTPMFGERSSI-----KKLLEERRRLVAT-FLDDQGLFPNNHTINEFQELHKEVFPTRNALILKIREVRQRRM 244
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Fly
Match: cic (gene:FBgn0262582 transcript:FBtr0305027)

HSP 1 Score: 111.694 bits (278), Expect = 4.764e-24
Identity = 51/94 (54.26%), Postives = 63/94 (67.02%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVG 2825
            +IRRPMNAFMIFS +HR  VHK++PN+DNR VS+ILGEWWY +   +K  Y +LA  +KDAHF+ +P WKW S    R K S S      K  G
Sbjct:  489 KIRRPMNAFMIFSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCS--KDRRKSSTSTATPGGKASG 580

HSP 2 Score: 97.4413 bits (241), Expect = 1.137e-19
Identity = 71/221 (32.13%), Postives = 103/221 (46.61%), Query Frame = 3 
Query: 4437 SASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQQ 5099
            S +A  K+K DE   +VL +VDF++K+  LPQF PE       QSP  I + +               PR+        N    P  KL    D     +     T   FFG DF    N       ++    +P +P         +PL +     +  G +K+LE RR+ V++LF E+ N FPTA+    +Q +H++VFP  Q L+ KIREVRQK++ Q
Sbjct: 1599 STAAALKKKNDEMNNSVLKQVDFEKKYKALPQFQPEDC-----QSPSAIAVPS--------------SPRVYGTNYRKKNTAPPPVQKLMCEDDSIDEPASAPPTTTQRFFGPDF---NNELKELESSDQTGRSPRTPK--------TPLQSARSDASEKGHRKVLETRRSLVLQLFAEHGN-FPTAQATMAFQSKHSDVFPRKQDLQLKIREVRQKLLGQ 1788
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Fly
Match: cic (gene:FBgn0262582 transcript:FBtr0334306)

HSP 1 Score: 111.309 bits (277), Expect = 5.604e-24
Identity = 51/94 (54.26%), Postives = 63/94 (67.02%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVG 2825
            +IRRPMNAFMIFS +HR  VHK++PN+DNR VS+ILGEWWY +   +K  Y +LA  +KDAHF+ +P WKW S    R K S S      K  G
Sbjct:  337 KIRRPMNAFMIFSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCS--KDRRKSSTSTATPGGKASG 428

HSP 2 Score: 95.5153 bits (236), Expect = 3.506e-19
Identity = 72/223 (32.29%), Postives = 104/223 (46.64%), Query Frame = 3 
Query: 4437 SASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDF--PLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQQ 5099
            S +A  K+K DE   NVL +VDF++K+  LPQF PE       QSP  I + +               PR+        N    P  KL    D     +     T   FFG DF   L     +    ++    +P +P         +PL +     +  G +K+LE RR+ V++LF E+ N FPTA+    +Q +H++VFP  Q L+ KIREVRQK++ Q
Sbjct: 1018 STAAALKKKNDE-MNNVLKQVDFEKKYKALPQFQPEDC-----QSPSAIAVPS--------------SPRVYGTNYRKKNTAPPPVQKLMCEDDSIDEPASAPPTTTQRFFGPDFNNELKDERLAELESSDQTGRSPRTPK--------TPLQSARSDASEKGHRKVLETRRSLVLQLFAEHGN-FPTAQATMAFQSKHSDVFPRKQDLQLKIREVRQKLLGQ 1211
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Fly
Match: cic (gene:FBgn0262582 transcript:FBtr0305029)

HSP 1 Score: 111.694 bits (278), Expect = 6.040e-24
Identity = 47/84 (55.95%), Postives = 61/84 (72.62%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNS 2795
            +IRRPMNAFMIFS +HR  VHK++PN+DNR VS+ILGEWWY +   +K  Y +LA  +KDAHF+ +P WKW S    +S  S +
Sbjct: 1227 KIRRPMNAFMIFSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCSKDRRKSSTSTA 1310

HSP 2 Score: 97.8265 bits (242), Expect = 1.054e-19
Identity = 71/221 (32.13%), Postives = 103/221 (46.61%), Query Frame = 3 
Query: 4437 SASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQQ 5099
            S +A  K+K DE   +VL +VDF++K+  LPQF PE       QSP  I + +               PR+        N    P  KL    D     +     T   FFG DF    N       ++    +P +P         +PL +     +  G +K+LE RR+ V++LF E+ N FPTA+    +Q +H++VFP  Q L+ KIREVRQK++ Q
Sbjct: 1908 STAAALKKKNDEMNNSVLKQVDFEKKYKALPQFQPEDC-----QSPSAIAVPS--------------SPRVYGTNYRKKNTAPPPVQKLMCEDDSIDEPASAPPTTTQRFFGPDF---NNELKELESSDQTGRSPRTPK--------TPLQSARSDASEKGHRKVLETRRSLVLQLFAEHGN-FPTAQATMAFQSKHSDVFPRKQDLQLKIREVRQKLLGQ 2097

HSP 3 Score: 81.6481 bits (200), Expect = 8.624e-15
Identity = 33/49 (67.35%), Postives = 43/49 (87.76%), Query Frame = 3 
Query: 1659 YRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRG 1805
            ++KGD+V++ +GVRKK+NGKQWRRLC    CTKESQRRG+CSRHL+ +G
Sbjct:  653 FKKGDIVESESGVRKKYNGKQWRRLCML--CTKESQRRGYCSRHLNQKG 699
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Fly
Match: cic (gene:FBgn0262582 transcript:FBtr0305026)

HSP 1 Score: 111.309 bits (277), Expect = 6.287e-24
Identity = 51/94 (54.26%), Postives = 63/94 (67.02%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVG 2825
            +IRRPMNAFMIFS +HR  VHK++PN+DNR VS+ILGEWWY +   +K  Y +LA  +KDAHF+ +P WKW S    R K S S      K  G
Sbjct:  489 KIRRPMNAFMIFSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCS--KDRRKSSTSTATPGGKASG 580

HSP 2 Score: 97.4413 bits (241), Expect = 1.023e-19
Identity = 71/221 (32.13%), Postives = 103/221 (46.61%), Query Frame = 3 
Query: 4437 SASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQQ 5099
            S +A  K+K DE   +VL +VDF++K+  LPQF PE       QSP  I + +               PR+        N    P  KL    D     +     T   FFG DF    N       ++    +P +P         +PL +     +  G +K+LE RR+ V++LF E+ N FPTA+    +Q +H++VFP  Q L+ KIREVRQK++ Q
Sbjct: 1170 STAAALKKKNDEMNNSVLKQVDFEKKYKALPQFQPEDC-----QSPSAIAVPS--------------SPRVYGTNYRKKNTAPPPVQKLMCEDDSIDEPASAPPTTTQRFFGPDF---NNELKELESSDQTGRSPRTPK--------TPLQSARSDASEKGHRKVLETRRSLVLQLFAEHGN-FPTAQATMAFQSKHSDVFPRKQDLQLKIREVRQKLLGQ 1359
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Fly
Match: cic (gene:FBgn0262582 transcript:FBtr0305028)

HSP 1 Score: 111.309 bits (277), Expect = 6.290e-24
Identity = 51/94 (54.26%), Postives = 63/94 (67.02%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVG 2825
            +IRRPMNAFMIFS +HR  VHK++PN+DNR VS+ILGEWWY +   +K  Y +LA  +KDAHF+ +P WKW S    R K S S      K  G
Sbjct:  489 KIRRPMNAFMIFSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCS--KDRRKSSTSTATPGGKASG 580

HSP 2 Score: 95.5153 bits (236), Expect = 3.911e-19
Identity = 72/223 (32.29%), Postives = 104/223 (46.64%), Query Frame = 3 
Query: 4437 SASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDF--PLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQQ 5099
            S +A  K+K DE   NVL +VDF++K+  LPQF PE       QSP  I + +               PR+        N    P  KL    D     +     T   FFG DF   L     +    ++    +P +P         +PL +     +  G +K+LE RR+ V++LF E+ N FPTA+    +Q +H++VFP  Q L+ KIREVRQK++ Q
Sbjct: 1170 STAAALKKKNDE-MNNVLKQVDFEKKYKALPQFQPEDC-----QSPSAIAVPS--------------SPRVYGTNYRKKNTAPPPVQKLMCEDDSIDEPASAPPTTTQRFFGPDFNNELKDERLAELESSDQTGRSPRTPK--------TPLQSARSDASEKGHRKVLETRRSLVLQLFAEHGN-FPTAQATMAFQSKHSDVFPRKQDLQLKIREVRQKLLGQ 1363
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Zebrafish
Match: cica (capicua transcriptional repressor a [Source:ZFIN;Acc:ZDB-GENE-060503-700])

HSP 1 Score: 116.316 bits (290), Expect = 3.245e-25
Identity = 50/83 (60.24%), Postives = 60/83 (72.29%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW------SSLKHGR 2777
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHFR +P WKW       SL  GR
Sbjct: 1304 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFRAHPDWKWCNKDRRKSLSEGR 1386

HSP 2 Score: 105.916 bits (263), Expect = 4.867e-22
Identity = 43/58 (74.14%), Postives = 52/58 (89.66%), Query Frame = 3 
Query: 1647 SQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRS 1820
            +Q+ Y+KGDVV TP G+RKKFNGKQWRRLCS+E C+KESQRRG+CSRHLSMR KE+ +
Sbjct:  677 AQQKYKKGDVVCTPTGIRKKFNGKQWRRLCSREGCSKESQRRGYCSRHLSMRTKEMEA 734

HSP 3 Score: 60.8474 bits (146), Expect = 2.321e-8
Identity = 72/272 (26.47%), Postives = 109/272 (40.07%), Query Frame = 3 
Query: 4320 KIKFKPPPLQLSTEIMTSPPKSASCVCTTDMLSANPKKKSASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESIN-----DNVAQSPRVI---NIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSA-----DVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            KIKF+PPPL+ +T+                            ALF                F+ +  +LP+F PE +       ++A SPR I     K   N  +  + D    PR   R L+  + + EPN   PKSA     D+ T   R + +T +I    D                                      P  SL     +++L+ RR  V++LF+E+   FP+A+  + +Q ++++ FPS   L+ KIREVRQKIMQ
Sbjct: 2251 KIKFRPPPLKSTTD------------------------SGDKALFGSS-------------FEERLKELPEFKPEDVLPSPNLQSLATSPRAILGSYRKKRRNSTDLDSTDDPTSPRRKSRRLS--SCSSEPN--TPKSAAKCEGDIFTF-DRTVGETEHILEELD------------------------------------RVPPSSL-----RRMLDQRRALVMQLFQEH-GFFPSAQATAAFQARYSDTFPSKVCLQLKIREVRQKIMQ 2438
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Zebrafish
Match: cicb (capicua transcriptional repressor b [Source:ZFIN;Acc:ZDB-GENE-030131-1966])

HSP 1 Score: 114.39 bits (285), Expect = 1.104e-24
Identity = 45/70 (64.29%), Postives = 56/70 (80.00%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW
Sbjct: 1396 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKW 1465

HSP 2 Score: 107.457 bits (267), Expect = 1.478e-22
Identity = 44/59 (74.58%), Postives = 52/59 (88.14%), Query Frame = 3 
Query: 1650 QKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSL 1826
            Q+ Y+KGDVV TPNG+RKKFNGKQWRRLCS+E C KESQRRG+CSRHLSMR KE+  ++
Sbjct:  773 QQKYKKGDVVCTPNGIRKKFNGKQWRRLCSREGCMKESQRRGYCSRHLSMRTKEMEGAV 831

HSP 3 Score: 59.3066 bits (142), Expect = 6.561e-8
Identity = 25/58 (43.10%), Postives = 43/58 (74.14%), Query Frame = 3 
Query: 4923 KKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            ++ L+ RR  V++LF+++   FP+A+  + +Q ++A++FP+   L+ KIREVRQKIMQ
Sbjct: 2507 RRTLDQRRALVMQLFQDH-GFFPSAQATAAFQARYADIFPTKVCLQLKIREVRQKIMQ 2563
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Zebrafish
Match: cicb (capicua transcriptional repressor b [Source:ZFIN;Acc:ZDB-GENE-030131-1966])

HSP 1 Score: 104.375 bits (259), Expect = 1.153e-21
Identity = 41/66 (62.12%), Postives = 52/66 (78.79%), Query Frame = 3 
Query: 2559 MNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            MNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW
Sbjct:    1 MNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKW 66

HSP 2 Score: 59.3066 bits (142), Expect = 4.989e-8
Identity = 25/58 (43.10%), Postives = 43/58 (74.14%), Query Frame = 3 
Query: 4923 KKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            ++ L+ RR  V++LF+++   FP+A+  + +Q ++A++FP+   L+ KIREVRQKIMQ
Sbjct: 1108 RRTLDQRRALVMQLFQDH-GFFPSAQATAAFQARYADIFPTKVCLQLKIREVRQKIMQ 1164
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Zebrafish
Match: bbx (BBX high mobility group box domain containing [Source:ZFIN;Acc:ZDB-GENE-091204-306])

HSP 1 Score: 79.337 bits (194), Expect = 1.102e-15
Identity = 32/71 (45.07%), Postives = 47/71 (66.20%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            R RRPMNAF++F  RHR  V +++P  DNR  ++IL +WW  +   EK+ Y  +A++ KDA  +  PG+KW
Sbjct:   83 RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKW 153
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Zebrafish
Match: bbx (BBX high mobility group box domain containing [Source:ZFIN;Acc:ZDB-GENE-091204-306])

HSP 1 Score: 83.5741 bits (205), Expect = 1.964e-15
Identity = 32/71 (45.07%), Postives = 47/71 (66.20%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            R RRPMNAF++F  RHR  V +++P  DNR  ++IL +WW  +   EK+ Y  +A++ KDA  +  PG+KW
Sbjct:   83 RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKW 153
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Xenopus
Match: lrrc4b (leucine rich repeat containing 4B [Source:Xenbase;Acc:XB-GENE-5945982])

HSP 1 Score: 114.39 bits (285), Expect = 1.723e-24
Identity = 45/70 (64.29%), Postives = 56/70 (80.00%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW
Sbjct: 1107 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKW 1176

HSP 2 Score: 107.071 bits (266), Expect = 2.897e-22
Identity = 44/58 (75.86%), Postives = 53/58 (91.38%), Query Frame = 3 
Query: 1647 SQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRS 1820
            +Q+ Y+KGDVV TPNG+RKKFNGKQWRRLCS+++C KESQRRG+CSRHLSMR KE+ S
Sbjct:  491 AQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSRDSCMKESQRRGYCSRHLSMRTKEMES 548

HSP 3 Score: 74.7146 bits (182), Expect = 1.831e-12
Identity = 68/233 (29.18%), Postives = 106/233 (45.49%), Query Frame = 3 
Query: 4452 FKRKLDEDTENVLAEVDFQRKFIDLPQFNPESIN-----DNVAQSPRVI------NIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLL-------TPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
             K+  D     VL+EVDF+ +F +LP+F PE +       ++A SPR I        KN T++ +  T D     R ++R     + + EPN   PKSA              +IF                             F   GN+A  LL        P  SL     ++ L+ RR  V++LF+E+   FP++++ + +Q +++++FP+   L+ KIREVRQKIMQ
Sbjct: 2276 LKKTFDSVDNRVLSEVDFEERFAELPEFKPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDL-DSSTEDPVSPKRKMRRR---SSCSSEPN--TPKSAKC----------EGDIF----------------------------TFERTGNEAEDLLGEMEYDKAPYSSL-----RRTLDQRRALVMQLFQEH-GFFPSSQSTAAFQSRYSDIFPTKVCLQLKIREVRQKIMQ 2458
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Xenopus
Match: prtfdc1 (phosphoribosyl transferase domain containing 1 [Source:Xenbase;Acc:XB-GENE-942165])

HSP 1 Score: 82.8037 bits (203), Expect = 4.502e-15
Identity = 32/71 (45.07%), Postives = 47/71 (66.20%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            R RRPMNAF++F  RHR  V +++P  DNR  ++IL +WW  +   EK+ Y  +A++ KDA  +  PG+KW
Sbjct:   77 RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAYLDPNEKQKYTDMAKEYKDAFMKANPGYKW 147
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Xenopus
Match: sox7 (SRY-box 7 [Source:NCBI gene;Acc:549080])

HSP 1 Score: 69.707 bits (169), Expect = 1.777e-11
Identity = 38/111 (34.23%), Postives = 62/111 (55.86%), Query Frame = 3 
Query: 2511 RSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVGKQVDLG 2843
            RSP + G    RIRRPMNAFM+++   R  +  QNP+  N  +S++LG+ W  +S  +K PY + A++L+  H ++YP +K+   +             + K + K+VD G
Sbjct:   31 RSPREKGSET-RIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALSPAQKRPYVEEAERLRVQHMQDYPNYKYRPRR-----------KKQIKRICKRVDTG 129
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Xenopus
Match: wasf1 (WASP family member 1 [Source:Xenbase;Acc:XB-GENE-978145])

HSP 1 Score: 69.707 bits (169), Expect = 3.240e-11
Identity = 30/76 (39.47%), Postives = 46/76 (60.53%), Query Frame = 3 
Query: 2529 GFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            G  G  I+RPMNAFM+++   R ++ +  P+  N ++S+ILG  W  MSN EK+PY +   +L   H   YP +K+
Sbjct:  354 GSRGSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMSNAEKQPYYEEQARLSRQHLERYPDYKY 429
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Xenopus
Match: wasf1 (WASP family member 1 [Source:Xenbase;Acc:XB-GENE-978145])

HSP 1 Score: 69.707 bits (169), Expect = 3.454e-11
Identity = 30/76 (39.47%), Postives = 46/76 (60.53%), Query Frame = 3 
Query: 2529 GFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            G  G  I+RPMNAFM+++   R ++ +  P+  N ++S+ILG  W  MSN EK+PY +   +L   H   YP +K+
Sbjct:  366 GSRGSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMSNAEKQPYYEEQARLSRQHLERYPDYKY 441
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Mouse
Match: Cic (capicua transcriptional repressor [Source:MGI Symbol;Acc:MGI:1918972])

HSP 1 Score: 114.39 bits (285), Expect = 1.023e-24
Identity = 45/70 (64.29%), Postives = 56/70 (80.00%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW
Sbjct:  200 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKW 269
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Mouse
Match: Cic (capicua transcriptional repressor [Source:MGI Symbol;Acc:MGI:1918972])

HSP 1 Score: 103.219 bits (256), Expect = 3.003e-21
Identity = 46/78 (58.97%), Postives = 59/78 (75.64%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRS 2780
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW +    +S
Sbjct: 1107 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKS 1184

HSP 2 Score: 99.3673 bits (246), Expect = 5.380e-20
Identity = 49/88 (55.68%), Postives = 62/88 (70.45%), Query Frame = 3 
Query: 1647 SQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITPGPSFNGHPSLFLSRDSNAGVD 1910
            +Q+ Y+KGDVV TPNG+RKKFNGKQWRRLCS++ C KESQRRG+CSRHLSMR KE+     +     GP   G P+   +R+ +   D
Sbjct:  475 AQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADS-----GPGGTGRPAGVAAREGSTEFD 557

HSP 3 Score: 59.6918 bits (143), Expect = 5.618e-8
Identity = 69/244 (28.28%), Postives = 106/244 (43.44%), Query Frame = 3 
Query: 4407 DMLSANPKKKSASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESIN-----DNVAQSPRVI---------NIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            ++ S+  K K      K+  D   + VL+EVDF+ +F +LP+F PE +       ++A SPR I         N  +L + PE    D     R ++R     + + EPN   PKSA              +IF    F  T        G       P S                         ++ L+ RR  V++LF+++   FP+A+  + +Q ++A++FPS   L+ KIREVRQKIMQ
Sbjct: 2226 EVTSSGKKMKVRPPPLKKTFDS-VDKVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPE----DPTSPKRKMRRR---SSCSSEPN--TPKSAKCE----------GDIF---TFDRTGTETEDVLGELEYEKVPYS-----------------------SLRRTLDQRRALVMQLFQDH-GFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQ 2422
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Mouse
Match: Cic (capicua transcriptional repressor [Source:MGI Symbol;Acc:MGI:1918972])

HSP 1 Score: 101.679 bits (252), Expect = 8.859e-21
Identity = 46/78 (58.97%), Postives = 59/78 (75.64%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRS 2780
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW +    +S
Sbjct:  200 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKS 277

HSP 2 Score: 58.5362 bits (140), Expect = 9.931e-8
Identity = 69/244 (28.28%), Postives = 106/244 (43.44%), Query Frame = 3 
Query: 4407 DMLSANPKKKSASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESIN-----DNVAQSPRVI---------NIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            ++ S+  K K      K+  D   + VL+EVDF+ +F +LP+F PE +       ++A SPR I         N  +L + PE    D     R ++R     + + EPN   PKSA              +IF    F  T        G       P S                         ++ L+ RR  V++LF+++   FP+A+  + +Q ++A++FPS   L+ KIREVRQKIMQ
Sbjct: 1320 EVTSSGKKMKVRPPPLKKTFDS-VDKVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPE----DPTSPKRKMRRR---SSCSSEPN--TPKSAKCE----------GDIF---TFDRTGTETEDVLGELEYEKVPYS-----------------------SLRRTLDQRRALVMQLFQDH-GFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQ 1516
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Mouse
Match: Cic (capicua transcriptional repressor [Source:MGI Symbol;Acc:MGI:1918972])

HSP 1 Score: 101.293 bits (251), Expect = 9.477e-21
Identity = 46/78 (58.97%), Postives = 59/78 (75.64%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRS 2780
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW +    +S
Sbjct:  200 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKS 277

HSP 2 Score: 60.8474 bits (146), Expect = 1.890e-8
Identity = 69/244 (28.28%), Postives = 105/244 (43.03%), Query Frame = 3 
Query: 4407 DMLSANPKKKSASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESIN-----DNVAQSPRVI---------NIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            ++ S+  K K      K+  D     VL+EVDF+ +F +LP+F PE +       ++A SPR I         N  +L + PE    D     R ++R     + + EPN   PKSA              +IF    F  T        G       P S                         ++ L+ RR  V++LF+++   FP+A+  + +Q ++A++FPS   L+ KIREVRQKIMQ
Sbjct: 1319 EVTSSGKKMKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPE----DPTSPKRKMRRR---SSCSSEPN--TPKSAKCE----------GDIF---TFDRTGTETEDVLGELEYEKVPYS-----------------------SLRRTLDQRRALVMQLFQDH-GFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQ 1516
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Mouse
Match: Bbx (bobby sox HMG box containing [Source:MGI Symbol;Acc:MGI:1917758])

HSP 1 Score: 84.3445 bits (207), Expect = 1.159e-15
Identity = 41/112 (36.61%), Postives = 60/112 (53.57%), Query Frame = 3 
Query: 2421 DIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            D V+  E D  +QD    E +          SP Q      R RRPMNAF++F  RHR  V +++P  DNR  ++IL +WW  +   EK+ Y  +A++ KDA  +  PG++W
Sbjct:   53 DKVQLLEADGLEQDVAETEDDE---------SPEQ------RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYRW 149
[Close]
BLAST of HMG box domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9U1H0|CIC_DROME (Putative transcription factor capicua OS=Drosophila melanogaster OX=7227 GN=cic PE=1 SV=2)

HSP 1 Score: 111.694 bits (278), Expect = 4.776e-23
Identity = 51/94 (54.26%), Postives = 63/94 (67.02%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVG 2825
            +IRRPMNAFMIFS +HR  VHK++PN+DNR VS+ILGEWWY +   +K  Y +LA  +KDAHF+ +P WKW S    R K S S      K  G
Sbjct:  489 KIRRPMNAFMIFSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCS--KDRRKSSTSTATPGGKASG 580

HSP 2 Score: 97.4413 bits (241), Expect = 1.139e-18
Identity = 71/221 (32.13%), Postives = 103/221 (46.61%), Query Frame = 3 
Query: 4437 SASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQQ 5099
            S +A  K+K DE   +VL +VDF++K+  LPQF PE       QSP  I + +               PR+        N    P  KL    D     +     T   FFG DF    N       ++    +P +P         +PL +     +  G +K+LE RR+ V++LF E+ N FPTA+    +Q +H++VFP  Q L+ KIREVRQK++ Q
Sbjct: 1599 STAAALKKKNDEMNNSVLKQVDFEKKYKALPQFQPEDC-----QSPSAIAVPS--------------SPRVYGTNYRKKNTAPPPVQKLMCEDDSIDEPASAPPTTTQRFFGPDF---NNELKELESSDQTGRSPRTPK--------TPLQSARSDASEKGHRKVLETRRSLVLQLFAEHGN-FPTAQATMAFQSKHSDVFPRKQDLQLKIREVRQKLLGQ 1788
[Close]
BLAST of HMG box domain-containing protein vs. UniProt/SwissProt
Match: sp|Q924A2|CIC_MOUSE (Protein capicua homolog OS=Mus musculus OX=10090 GN=Cic PE=1 SV=2)

HSP 1 Score: 103.219 bits (256), Expect = 2.100e-20
Identity = 46/78 (58.97%), Postives = 59/78 (75.64%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRS 2780
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW +    +S
Sbjct: 1107 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKS 1184

HSP 2 Score: 99.3673 bits (246), Expect = 3.763e-19
Identity = 49/88 (55.68%), Postives = 62/88 (70.45%), Query Frame = 3 
Query: 1647 SQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITPGPSFNGHPSLFLSRDSNAGVD 1910
            +Q+ Y+KGDVV TPNG+RKKFNGKQWRRLCS++ C KESQRRG+CSRHLSMR KE+     +     GP   G P+   +R+ +   D
Sbjct:  475 AQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADS-----GPGGTGRPAGVAAREGSTEFD 557

HSP 3 Score: 59.6918 bits (143), Expect = 3.930e-7
Identity = 69/244 (28.28%), Postives = 106/244 (43.44%), Query Frame = 3 
Query: 4407 DMLSANPKKKSASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESIN-----DNVAQSPRVI---------NIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            ++ S+  K K      K+  D   + VL+EVDF+ +F +LP+F PE +       ++A SPR I         N  +L + PE    D     R ++R     + + EPN   PKSA              +IF    F  T        G       P S                         ++ L+ RR  V++LF+++   FP+A+  + +Q ++A++FPS   L+ KIREVRQKIMQ
Sbjct: 2226 EVTSSGKKMKVRPPPLKKTFDS-VDKVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPE----DPTSPKRKMRRR---SSCSSEPN--TPKSAKCE----------GDIF---TFDRTGTETEDVLGELEYEKVPYS-----------------------SLRRTLDQRRALVMQLFQDH-GFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQ 2422
[Close]
BLAST of HMG box domain-containing protein vs. UniProt/SwissProt
Match: sp|Q96RK0|CIC_HUMAN (Protein capicua homolog OS=Homo sapiens OX=9606 GN=CIC PE=1 SV=2)

HSP 1 Score: 101.293 bits (251), Expect = 7.342e-20
Identity = 46/78 (58.97%), Postives = 59/78 (75.64%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRS 2780
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW +    +S
Sbjct:  200 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKS 277

HSP 2 Score: 59.6918 bits (143), Expect = 3.340e-7
Identity = 66/231 (28.57%), Postives = 102/231 (44.16%), Query Frame = 3 
Query: 4452 FKRKLDEDTENVLAEVDFQRKFIDLPQFNPESIN-----DNVAQSPRVI---------NIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLL--TPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
             K+  D     VL+EVDF+ +F +LP+F PE +       ++A SPR I         N  +L + PE    D     R ++R     + + EPN   PKSA              +IF                             F   G +A  +L       +  S  ++ L+ RR  V++LF+++   FP+A+  + +Q ++A++FPS   L+ KIREVRQKIMQ
Sbjct: 1338 LKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPE----DPTSPKRKMRRR---SSCSSEPN--TPKSAKCE----------GDIF----------------------------TFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDH-GFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQ 1520
[Close]
BLAST of HMG box domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8VBW5|BBX_MOUSE (HMG box transcription factor BBX OS=Mus musculus OX=10090 GN=Bbx PE=1 SV=2)

HSP 1 Score: 83.9593 bits (206), Expect = 1.035e-14
Identity = 41/112 (36.61%), Postives = 60/112 (53.57%), Query Frame = 3 
Query: 2421 DIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            D V+  E D  +QD    E +          SP Q      R RRPMNAF++F  RHR  V +++P  DNR  ++IL +WW  +   EK+ Y  +A++ KDA  +  PG++W
Sbjct:   53 DKVQLLEADGLEQDVAETEDDE---------SPEQ------RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYRW 149
[Close]
BLAST of HMG box domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8WY36|BBX_HUMAN (HMG box transcription factor BBX OS=Homo sapiens OX=9606 GN=BBX PE=1 SV=1)

HSP 1 Score: 82.4185 bits (202), Expect = 3.034e-14
Identity = 32/71 (45.07%), Postives = 47/71 (66.20%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            R RRPMNAF++F  RHR  V +++P  DNR  ++IL +WW  +   EK+ Y  +A++ KDA  +  PG+KW
Sbjct:   79 RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKW 149
[Close]
BLAST of HMG box domain-containing protein vs. TrEMBL
Match: A0A5J4NGF4 (HMG box domain-containing protein (Fragment) OS=Paragonimus westermani OX=34504 GN=DEA37_0006294 PE=4 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 5.878e-31
Identity = 139/453 (30.68%), Postives = 204/453 (45.03%), Query Frame = 3 
Query:  675 NLLNLSDWHKLPVLLRMENKSIVSYNRATIILSNNNDATVSVQLNSHSASCDNPDSCDINLVDLDQNYPLLIADTPPSIAQLTDKARICYHTS---DGTFRCGTI-TNKTDGDSSTSNQIRNSSRLYTIIPENSSNTTQPEYQKCSRAQLRILKLPWQEELDELL-------TALKMEYEDDVCENPVIALVTKYTESQGFEE----MSTSK-SDSDVNFE--------VKVENFEKQFVESESFTSSNLLSDIPTVPKINDGTPRNSSSSVF--------------NATNLITSGSNQESVIGIFNAEPDHNMVATNTNRSLIL--SEVGSAIGH------KKSFQLSDKMD-------------------------RNNSSNSLRSFGGCNLQSQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRS 1820
             +L+L  W    VL+ + +K +  Y   T++  N   + V+V+LN  S      D+     + L +  P +I D  P   QLTD   +C+  +   D  +  G +  +K   + ST NQ R   R+Y +  + +S T        SRA LR+L  PWQ+ELD+++       T       D+  E+P    +       G  +    +ST+K S  D+N            V      +V   + TS   L+D+      +  TP + SS  F                T  ++SG  QES      ++P   +  T + RS  +    VGS  GH      +K F LSD+                           R  + +S+       L + + ++KGDVVKT NGVRKKFNGKQWRRLCS++ C+KESQRRGFCSRHLSM+GKEIR+
Sbjct:   47 TMLDLKPWLDHHVLV-LTSKGV--YQPGTVVEMNQTKSLVTVRLNQQS------DTYVAVAISLAEAPPAVIDDAIPHANQLTDGTPVCFRETLLDDRRYVTGVLDYSKQMMNCSTGNQQR---RMYPVRSDANSCTVY-----LSRAHLRLLTAPWQDELDDIVNLNVAPATVTSGVKSDEFSEHPTAEELPGLGHRNGLSDKSMDLSTNKPSTPDLNTSDIAKPKSSFPVRPSSHSYVPYSTPTS---LNDLVNATVADLVTPVSCSSVHFPLVSSMSNTQWDPSTLTPRLSSGFRQES------SDPVTCVAVTTSPRSTDVDSKHVGSLSGHPFTSSTRKPFSLSDQTAGSFSFPVASQRPEGTSSGKYHPTGARWTTGSSVMGSSLNVLAAHQRFKKGDVVKTQNGVRKKFNGKQWRRLCSRDGCSKESQRRGFCSRHLSMKGKEIRA 473

HSP 2 Score: 120.553 bits (301), Expect = 2.378e-23
Identity = 46/72 (63.89%), Postives = 58/72 (80.56%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSS 2762
            +RRPMNAF+IFSMRHRGEV +  P  DNR  SQILGEWWY++   ++ PYQKLA++LK AHF+ +P WKWS+
Sbjct:  753 VRRPMNAFIIFSMRHRGEVLRLYPTMDNRVASQILGEWWYKLGAADRAPYQKLARELKAAHFQYHPNWKWSA 824
[Close]
BLAST of HMG box domain-containing protein vs. TrEMBL
Match: A0A183B819 (HMG box domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS15354 PE=4 SV=1)

HSP 1 Score: 132.494 bits (332), Expect = 4.890e-29
Identity = 65/134 (48.51%), Postives = 90/134 (67.16%), Query Frame = 3 
Query: 2421 DIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEV 2822
            DI KQ E  S + ++  + S +K  + S + S ++H      +RRPMNAF++FSMRHRGEVH+  PNKDNR  SQILGEWWY++S  EK  YQKLA++LK AHFR+ P W+WS+ +  RS  S +   T + ++
Sbjct:   17 DIDKQMENCSNEPESSESRSFSKFRRASSLISSSRH------VRRPMNAFILFSMRHRGEVHRLYPNKDNRVASQILGEWWYKLSAEEKAEYQKLARELKAAHFRHNPDWRWSAKERRRSAPSTTGNSTSSADI 144
[Close]
BLAST of HMG box domain-containing protein vs. TrEMBL
Match: A0A4Z2D9N9 (Protein capicua OS=Schistosoma japonicum OX=6182 GN=EWB00_003153 PE=4 SV=1)

HSP 1 Score: 136.732 bits (343), Expect = 2.736e-28
Identity = 70/167 (41.92%), Postives = 98/167 (58.68%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSS---------------LKHGRSKFSNSYEDTENKEVGKQVDLGNNKPCFEESDSKFNGQETNKVLNESLSQTPPPISVPI-----DANVSTHNNTH 2987
            +RRPMNAF+IFSMRHR EVH+  PNKDNR  SQILG+WWY +   EK PYQ+LA++LK AHF+++P WKWSS               L H RS+ S    D++N  +   + +GNN      + S+ N  ++N VL  S +     +++P      D  ++ +NN H
Sbjct:  372 VRRPMNAFIIFSMRHRSEVHRLYPNKDNRVASQILGDWWYHLDASEKAPYQQLARELKAAHFQSFPNWKWSSKQRRSSESGSNKKQYLTHHRSETSTPVCDSDNLLLKNTLSVGNNSNLLSVACSEIN--DSNSVLTNSATNRKSTVALPQSNRKNDGVINQNNNCH 536

HSP 2 Score: 91.2781 bits (225), Expect = 2.207e-14
Identity = 89/303 (29.37%), Postives = 144/303 (47.52%), Query Frame = 3 
Query: 4317 AKIKFKPPPLQLSTEIMTSPP---------KSASCVCTTDMLSANPKKKSASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPE-----CLTADHGCKPRILKRPLTPGNQNE----EPNHKLPKSADVATLRS--------RFMSDTNNIFFGSDFP------LT-------INSGSGYSGTNSIA-NTPLSP--NFLANGNKASPLLTPN-GSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            A  K KPPPL+L  ++  S           KS       +  SA+    +A+   KRK +E TENVLA+++F+ +F  LP+F P +I    A   RV ++     +P      C  ++      +   P    NQ       PN  L  S ++    S              +N+FFG++FP      LT        NS S  +  N ++ N P++P  ++ +  N+   ++ P+    N + SK IL  RR  V++LF+E   LFP+   ++ +Q+++A+ F S Q L+ KIRE+R++IMQ
Sbjct:  873 ASSKSKPPPLKLECDLFHSKSINENMEQCNKSTGKSTLCEPFSAD----AANRCCKRKFNETTENVLAQINFRHRFSYLPKFIPNTIT--AAPPQRVSSLIPTDQLPMLSSGPCFYSESIQTGSVTPTPSIDTNQQWCRLISPNSHLSDSENIHQNFSPKKLDADKSIQCSEDNVFFGANFPNINEFKLTNSLNPPICNSSSQSTLNNQLSRNHPIAPKTHYKSPLNQKLSMMIPHLTETNIANSKSILHIRRKLVLQLFQE-YGLFPSIPAITHFQQRYASYFSSRQALQLKIREIRRRIMQ 1168
[Close]
BLAST of HMG box domain-containing protein vs. TrEMBL
Match: A0A3R7JLF4 (Protein capicua-like protein (Fragment) OS=Clonorchis sinensis OX=79923 GN=CIC PE=4 SV=1)

HSP 1 Score: 136.346 bits (342), Expect = 3.916e-28
Identity = 129/446 (28.92%), Postives = 188/446 (42.15%), Query Frame = 3 
Query:  681 LNLSDWHKLPVLLRMENKSIVSYNRATIILSNNNDATVSVQLNSHSASCDNPDSCDINLVDLDQNYPLLIADTPPSIAQLTDKARICYHTSDGTFRCGTITNKTDGDSSTSNQIR-------NSSRLYTIIPENSSNTTQPEYQKCSRAQLRILKLPWQEELDELLTALKMEYED--------------------------------DV------CENPVIALVTKYTESQGFEEMSTSKSDSDVNFEVKVENFEKQFVESESFTSSNLL----SDIPTVPKI--NDGTPRNSSS--SVFNA------TNLITSGSNQESVIGIFNAEPDHNMVATNTNRSLILSEVGSAIGHKKSFQLSDKMDRNNSSNSLRS-------FGGCNLQSQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRS 1820
            L+LS W    VL++  +     Y    I+        + V+L+ HS S    ++  + ++    + P +I D  P   QL D  R+CY  +            TDG    + ++        N  RLY   P +  +T        +R  LR+L  PWQ+ELD+L    +  +ED                                D+       ++PV+          G   +S   +  DVN  V  E    + + S+   +S       S  P    +  N G P       ++  A      T L   G N  S    ++A P           +L LS +G  +G   S + +    + + +N L +       FG   +  Q+ ++KGDVVKTPNGVRKKFNGKQWRRLCS+E CTKESQRRGFCSRHLSM+GKEIR+
Sbjct:   69 LDLSPWMDHHVLVQTASGF---YQPGIILNVEKTTGELVVRLD-HSDS----NTILVEILSSSTSEPRVIDDAIPHANQLIDGIRVCYRDT-----------ATDGRRYATGRLNFRNRVPLNHQRLY---PVDCDSTVPSSTLFLTRTHLRLLVAPWQDELDDLQLPSETTHEDLGPPNELTSATHNSRNESPTSECVQVEPDKAVDLGMTIRDADSPVLLDSVSVPSHGGPSIVSGDMTSEDVNRSVAFERSSSKPIPSDQLIASETTNFSTSSAPPTYSVANNGGVPETEPGPLTILGAVRGSEPTPLAQLGRNSTS----YSASP---------ASALSLSLLGPCLGTSSSIRFTAAGPKWSPANLLAATTSLPNTFG---VHHQR-FKKGDVVKTPNGVRKKFNGKQWRRLCSREGCTKESQRRGFCSRHLSMKGKEIRA 475

HSP 2 Score: 132.494 bits (332), Expect = 6.776e-27
Identity = 56/88 (63.64%), Postives = 65/88 (73.86%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTE 2810
            +RRPMNAF++FSMRHR EVH+  PNKDNR  SQILGEWWY+M+  EK  YQKLA++LK AHF  YP WKWSS K  R     S  DT+
Sbjct:  752 VRRPMNAFILFSMRHRAEVHRLYPNKDNRVASQILGEWWYRMATEEKAHYQKLAKELKTAHFHYYPNWKWSSPKERRKSAPLSRHDTD 839
[Close]
BLAST of HMG box domain-containing protein vs. TrEMBL
Match: A0A183KNU8 (HMG box domain-containing protein OS=Schistosoma curassoni OX=6186 GN=SCUD_LOCUS16727 PE=4 SV=1)

HSP 1 Score: 125.946 bits (315), Expect = 1.366e-27
Identity = 58/103 (56.31%), Postives = 72/103 (69.90%), Query Frame = 3 
Query: 2484 NKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSN 2792
            NK+ K S I + T        +RRPMNAF+IFSMRHR EVH+  PNKDNR  SQILG+WWY +   EK PYQ+LA++LK AHF+ +P WKWSS +  RS+  N
Sbjct:   73 NKKLKLSTILNKTNQD--KKHVRRPMNAFIIFSMRHRSEVHRLYPNKDNRVASQILGDWWYHLDASEKAPYQQLARELKAAHFQLFPNWKWSSKQRLRSESGN 173
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Cavefish
Match: cica (capicua transcriptional repressor a [Source:ZFIN;Acc:ZDB-GENE-060503-700])

HSP 1 Score: 115.161 bits (287), Expect = 5.711e-25
Identity = 50/83 (60.24%), Postives = 60/83 (72.29%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW------SSLKHGR 2777
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHFR +P WKW       SL  GR
Sbjct:  965 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFRAHPDWKWCNKDRRKSLSEGR 1047

HSP 2 Score: 104.76 bits (260), Expect = 8.705e-22
Identity = 43/58 (74.14%), Postives = 52/58 (89.66%), Query Frame = 3 
Query: 1647 SQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRS 1820
            +Q+ Y+KGDVV TP G+RKKFNGKQWRRLCS+E C+KESQRRG+CSRHLSMR KE+ +
Sbjct:  452 AQQKYKKGDVVCTPTGIRKKFNGKQWRRLCSREGCSKESQRRGYCSRHLSMRTKEMEA 509

HSP 3 Score: 62.003 bits (149), Expect = 7.206e-9
Identity = 25/58 (43.10%), Postives = 43/58 (74.14%), Query Frame = 3 
Query: 4923 KKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            ++ L+ RR  V++LF+E+ + FP+A+  + +Q ++++ FP+   L+ KIREVRQKIMQ
Sbjct: 1580 RRTLDQRRALVMQLFQEHGSFFPSAQATAAFQARYSDTFPTKVCLQLKIREVRQKIMQ 1637
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Cavefish
Match: cicb (capicua transcriptional repressor b [Source:ZFIN;Acc:ZDB-GENE-030131-1966])

HSP 1 Score: 114.005 bits (284), Expect = 1.220e-24
Identity = 45/70 (64.29%), Postives = 56/70 (80.00%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW
Sbjct: 1011 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKW 1080

HSP 2 Score: 106.686 bits (265), Expect = 1.799e-22
Identity = 44/59 (74.58%), Postives = 54/59 (91.53%), Query Frame = 3 
Query: 1647 SQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSS 1823
            +Q+ Y+KGDVV TPNG+RKKFNGKQWRRLCSK++C KESQRRG+CSRHLSMR KE+ ++
Sbjct:  388 AQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSKDSCMKESQRRGYCSRHLSMRTKEMEAA 446
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Cavefish
Match: bbx (BBX high mobility group box domain containing [Source:NCBI gene;Acc:103035035])

HSP 1 Score: 84.3445 bits (207), Expect = 9.027e-16
Identity = 32/71 (45.07%), Postives = 47/71 (66.20%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            R RRPMNAF++F  RHR  V +++P  DNR  ++IL +WW  +   EK+ Y  +A++ KDA  +  PG+KW
Sbjct:   85 RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLEPSEKQKYTDMAKEYKDAFMKANPGYKW 155
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Cavefish
Match: bbx (BBX high mobility group box domain containing [Source:NCBI gene;Acc:103035035])

HSP 1 Score: 84.3445 bits (207), Expect = 9.027e-16
Identity = 32/71 (45.07%), Postives = 47/71 (66.20%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            R RRPMNAF++F  RHR  V +++P  DNR  ++IL +WW  +   EK+ Y  +A++ KDA  +  PG+KW
Sbjct:   85 RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLEPSEKQKYTDMAKEYKDAFMKANPGYKW 155
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Cavefish
Match: bbx (BBX high mobility group box domain containing [Source:NCBI gene;Acc:103035035])

HSP 1 Score: 84.3445 bits (207), Expect = 9.027e-16
Identity = 32/71 (45.07%), Postives = 47/71 (66.20%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            R RRPMNAF++F  RHR  V +++P  DNR  ++IL +WW  +   EK+ Y  +A++ KDA  +  PG+KW
Sbjct:   85 RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLEPSEKQKYTDMAKEYKDAFMKANPGYKW 155
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008165.1 (pep scaffold:Pmarinus_7.0:GL479973:18969:29522:-1 gene:ENSPMAG00000007384.1 transcript:ENSPMAT00000008165.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.4698 bits (158), Expect = 5.265e-12
Identity = 29/72 (40.28%), Postives = 46/72 (63.89%), Query Frame = 3 
Query: 2541 PRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            P I+RPMNAFM+++   R ++ +  P+  N ++S+ILG  W  MS+ EK+PY +   +L   H   YPG+K+
Sbjct:   59 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKAMSSQEKQPYYEEQARLSKLHLERYPGYKY 130
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Sea Lamprey
Match: sox12 (SRY-box transcription factor 12 [Source:ZFIN;Acc:ZDB-GENE-040724-33])

HSP 1 Score: 64.6994 bits (156), Expect = 8.605e-11
Identity = 27/78 (34.62%), Postives = 49/78 (62.82%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRS 2780
            I+RPMNAFM++S   R ++  ++P+  N  +S+ LG  W Q+ + EK P+ + A++L+  H  +YP +K+   K  ++
Sbjct:   60 IKRPMNAFMVWSQIERRKIMMESPDVHNAEISKRLGRRWKQLKDCEKVPFMREAERLRLKHMADYPDYKYRPRKKAKT 137
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Sea Lamprey
Match: hbp1 (HMG-box transcription factor 1 [Source:ZFIN;Acc:ZDB-GENE-050522-414])

HSP 1 Score: 65.0846 bits (157), Expect = 1.055e-10
Identity = 37/79 (46.84%), Postives = 44/79 (55.70%), Query Frame = 3 
Query: 2514 SPTQHGFMGP---------RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKD 2723
            SP   G M P         R +RPMNAFM+F+ R R E  K  P KDNRAVS +LGE W +M   EK  Y+  A+ L D
Sbjct:  387 SPGTAGPMAPAPATPNTPMRNKRPMNAFMLFAKRFRVEYTKMYPGKDNRAVSVMLGERWKRMKPEEKLVYELEAKALAD 465
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Sea Lamprey
Match: sox4b (SRY-box transcription factor 4b [Source:ZFIN;Acc:ZDB-GENE-040426-1274])

HSP 1 Score: 63.1586 bits (152), Expect = 2.654e-10
Identity = 28/77 (36.36%), Postives = 48/77 (62.34%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGR 2777
            I+RPMNAFM++S   R ++ +Q+P+  N  +S+ LG  W Q+   EK P+ + A++L+  H  +YP +K+   K  +
Sbjct:   62 IKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGRRWKQLKESEKVPFIREAERLRLKHMADYPDYKYRPRKKAK 138
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010223.1 (pep scaffold:Pmarinus_7.0:GL478813:2555:9375:-1 gene:ENSPMAG00000009255.1 transcript:ENSPMAT00000010223.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 1.612e-9
Identity = 27/81 (33.33%), Postives = 48/81 (59.26%), Query Frame = 3 
Query: 2541 PRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSK 2783
            PRI RPMNAFM+++   R  + KQNP+  N  +S++LG+ W  ++   + P  + A++L+  H   +P +K+   +  + K
Sbjct:    4 PRIPRPMNAFMVWAKDERRRLAKQNPDLHNAELSKMLGKSWRALTPESRRPCVEEAERLRLLHLSEHPDYKYRPRRKKQPK 84
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Nematostella
Match: EDO35373 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLM5])

HSP 1 Score: 80.8777 bits (198), Expect = 1.377e-18
Identity = 35/57 (61.40%), Postives = 45/57 (78.95%), Query Frame = 3 
Query: 2550 RRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLK 2720
            RRPMNAFMIFS RHR  VH+++P++DNR VS+ILGEWWY +   EK+ Y  LA Q++
Sbjct:    1 RRPMNAFMIFSKRHRALVHQKHPHQDNRTVSKILGEWWYALGPEEKQSYNALAAQVR 57
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Nematostella
Match: EDO36144 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJD9])

HSP 1 Score: 63.5438 bits (153), Expect = 3.656e-12
Identity = 32/69 (46.38%), Postives = 46/69 (66.67%), Query Frame = 3 
Query: 2550 RRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPG-WK 2753
            +RPMNAFM+F+ R+R E+ + +P KDNRA+S ILG+ W  M   E++ Y   A+QL + H +  P  WK
Sbjct:   13 KRPMNAFMLFAKRYRLEITQAHPGKDNRAISVILGDKWKSMKQEERKQYVMEAKQLAEEHKKVNPDCWK 81
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Nematostella
Match: EDO37719 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEY6])

HSP 1 Score: 59.6918 bits (143), Expect = 6.075e-11
Identity = 28/69 (40.58%), Postives = 44/69 (63.77%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGW 2750
            +++RPMNAFMI++  HR  + K+ P  +N  +S  LGE W  +S+ +++PY   A +LKD H   +P W
Sbjct:    8 KVKRPMNAFMIWARLHRSTIAKRYPQANNAEISIRLGEIWNDLSSEQQKPYFDEATRLKDKHKAEHPNW 76
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Nematostella
Match: EDO44142 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWK8])

HSP 1 Score: 65.855 bits (159), Expect = 6.089e-11
Identity = 42/141 (29.79%), Postives = 71/141 (50.35%), Query Frame = 3 
Query: 2544 RIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVGKQVDLGNNKPCFEESDSKFNGQET----NKVLNESLSQTPPPISVPI 2954
            RI+RPMNAFM+++   R  +   NP   N  +S++LG  W  +++ +K P+   A++L+  H ++YP +K+   +   SK   + + +     G +V   N   C      K +GQET    N ++  S  Q P   + PI
Sbjct:   72 RIKRPMNAFMVWAQVERRRLADANPELHNAELSKMLGLTWRALNSTQKRPFVDEAERLRLQHMQDYPNYKYRPRRRKHSK--RAAKRSTGAAAGSKV---NGTAC-----QKSSGQETVSRFNCLVESSFFQVPGTPNSPI 202
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Nematostella
Match: EDO38755 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC09])

HSP 1 Score: 58.151 bits (139), Expect = 2.547e-10
Identity = 26/70 (37.14%), Postives = 46/70 (65.71%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            ++RPMN FM++S   R ++ ++NP  +N  +S++LG  W ++S  EKEPY + A+ L + H   +P +K+
Sbjct:    8 VKRPMNCFMVWSREKRCQILQENPGINNARLSKLLGMAWKKLSVEEKEPYIEKAKHLTEMHKEKHPDYKY 77
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Medaka
Match: cica (protein capicua homolog [Source:NCBI gene;Acc:101156834])

HSP 1 Score: 117.857 bits (294), Expect = 9.293e-26
Identity = 49/103 (47.57%), Postives = 69/103 (66.99%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW------SSLKHGRSKFSNSYEDTENKEVGKQVD 2837
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA ++K+AHF+ +P WKW       S+  GR  F  + ++   + + + +D
Sbjct: 1358 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPNEKQQYHDLAFKVKEAHFKAHPDWKWCNKDRRKSMSEGRPSFGGTPKEARERSMSESID 1460

HSP 2 Score: 105.531 bits (262), Expect = 4.968e-22
Identity = 43/59 (72.88%), Postives = 53/59 (89.83%), Query Frame = 3 
Query: 1647 SQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSS 1823
            +Q+ Y+KGDVV TP G+RKKFNGKQWRRLCS+E C+KESQRRG+CSRHLSM+ KE+ +S
Sbjct:  725 AQQKYKKGDVVCTPTGIRKKFNGKQWRRLCSREGCSKESQRRGYCSRHLSMKTKEMEAS 783

HSP 3 Score: 56.9954 bits (136), Expect = 2.951e-7
Identity = 74/263 (28.14%), Postives = 117/263 (44.49%), Query Frame = 3 
Query: 4371 SPPKSASCVCTTDMLSANPKKKSASALFK------RKLDEDTENVLAEVDFQRKFIDLPQFNPESIN-----DNVAQSPRVI------NIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLL-TPNGS---LNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            SPP ++S +       A  +  S+S   K      +K  +  + VL+E  F+ +F +LP+FNPE +       ++A SPR I        +N T++    T +    PR   R L+  + + EPN   PKSA              +IF                             F    +KA P    P G    ++ S  ++ L+ RR  V++LF+E+   FPTA+  + +Q ++++ FP+   L+ KIREVRQKIMQ
Sbjct: 2210 SPPPTSSGLDPPPPPPAEKEAPSSSKRNKFRPPPLKKAPDSHDKVLSETYFEERFAELPEFNPEEVLPSPTLQSLATSPRAILGSYRKKRRNSTDL--EATGEEPSSPRRKTRRLS--SCSSEPN--TPKSAAKCE---------GDIF----------------------------TF----DKAGPEGDVPQGDSERISYSSLRRTLDQRRALVMQLFQEH-GFFPTAQATAAFQARYSDTFPTKVCLQLKIREVRQKIMQ 2424
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Medaka
Match: cicb (capicua transcriptional repressor [Source:NCBI gene;Acc:101174050])

HSP 1 Score: 115.161 bits (287), Expect = 6.307e-25
Identity = 45/70 (64.29%), Postives = 56/70 (80.00%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW
Sbjct: 1411 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKW 1480

HSP 2 Score: 108.227 bits (269), Expect = 6.724e-23
Identity = 44/56 (78.57%), Postives = 51/56 (91.07%), Query Frame = 3 
Query: 1647 SQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEI 1814
            +Q+ Y+KGDVV TPNG+RKKFNGKQWRRLCS+E C KESQRRG+CSRHLSMR KE+
Sbjct:  739 AQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSREGCMKESQRRGYCSRHLSMRTKEM 794

HSP 3 Score: 59.6918 bits (143), Expect = 4.455e-8
Identity = 25/58 (43.10%), Postives = 43/58 (74.14%), Query Frame = 3 
Query: 4923 KKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            ++ L+ RR  V++LF+E +  FP+A+  + +Q +++++FP+   L+ KIREVRQKIMQ
Sbjct: 2585 RRTLDQRRALVMQLFQE-QGFFPSAQATAAFQTRYSDIFPTKVCLQLKIREVRQKIMQ 2641
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Medaka
Match: cicb (capicua transcriptional repressor [Source:NCBI gene;Acc:101174050])

HSP 1 Score: 115.161 bits (287), Expect = 6.724e-25
Identity = 45/70 (64.29%), Postives = 56/70 (80.00%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW
Sbjct: 1411 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKW 1480

HSP 2 Score: 108.227 bits (269), Expect = 6.992e-23
Identity = 44/56 (78.57%), Postives = 51/56 (91.07%), Query Frame = 3 
Query: 1647 SQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEI 1814
            +Q+ Y+KGDVV TPNG+RKKFNGKQWRRLCS+E C KESQRRG+CSRHLSMR KE+
Sbjct:  739 AQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSREGCMKESQRRGYCSRHLSMRTKEM 794

HSP 3 Score: 59.6918 bits (143), Expect = 4.338e-8
Identity = 25/58 (43.10%), Postives = 43/58 (74.14%), Query Frame = 3 
Query: 4923 KKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            ++ L+ RR  V++LF+E +  FP+A+  + +Q +++++FP+   L+ KIREVRQKIMQ
Sbjct: 2547 RRTLDQRRALVMQLFQE-QGFFPSAQATAAFQTRYSDIFPTKVCLQLKIREVRQKIMQ 2603
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Medaka
Match: cicb (capicua transcriptional repressor [Source:NCBI gene;Acc:101174050])

HSP 1 Score: 115.161 bits (287), Expect = 6.724e-25
Identity = 45/70 (64.29%), Postives = 56/70 (80.00%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW
Sbjct: 1411 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKW 1480

HSP 2 Score: 108.227 bits (269), Expect = 6.992e-23
Identity = 44/56 (78.57%), Postives = 51/56 (91.07%), Query Frame = 3 
Query: 1647 SQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEI 1814
            +Q+ Y+KGDVV TPNG+RKKFNGKQWRRLCS+E C KESQRRG+CSRHLSMR KE+
Sbjct:  739 AQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSREGCMKESQRRGYCSRHLSMRTKEM 794

HSP 3 Score: 59.6918 bits (143), Expect = 4.338e-8
Identity = 25/58 (43.10%), Postives = 43/58 (74.14%), Query Frame = 3 
Query: 4923 KKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            ++ L+ RR  V++LF+E +  FP+A+  + +Q +++++FP+   L+ KIREVRQKIMQ
Sbjct: 2547 RRTLDQRRALVMQLFQE-QGFFPSAQATAAFQTRYSDIFPTKVCLQLKIREVRQKIMQ 2603
[Close]
BLAST of HMG box domain-containing protein vs. Ensembl Medaka
Match: cicb (capicua transcriptional repressor [Source:NCBI gene;Acc:101174050])

HSP 1 Score: 113.235 bits (282), Expect = 1.713e-24
Identity = 45/70 (64.29%), Postives = 56/70 (80.00%), Query Frame = 3 
Query: 2547 IRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKW 2756
            IRRPMNAFMIFS RHR  VH+++PN+DNR VS+ILGEWWY +   EK+ Y  LA Q+K+AHF+ +P WKW
Sbjct:  169 IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKW 238

HSP 2 Score: 59.6918 bits (143), Expect = 3.374e-8
Identity = 25/58 (43.10%), Postives = 43/58 (74.14%), Query Frame = 3 
Query: 4923 KKILECRRNFVVKLFKENENLFPTAETVSRYQKQHANVFPSIQILKHKIREVRQKIMQ 5096
            ++ L+ RR  V++LF+E +  FP+A+  + +Q +++++FP+   L+ KIREVRQKIMQ
Sbjct: 1305 RRTLDQRRALVMQLFQE-QGFFPSAQATAAFQTRYSDIFPTKVCLQLKIREVRQKIMQ 1361
[Close]
BLAST of HMG box domain-containing protein vs. Planmine SMEST
Match: SMESG000017541.1 (SMESG000017541.1)

HSP 1 Score: 1561.2 bits (4041), Expect = 0.000e+0
Identity = 902/962 (93.76%), Postives = 904/962 (93.97%), Query Frame = 3 
Query: 2130 PELDKGPPNDDYKSXXXXXXXXXXXXXVAHWYQLLPILQNCPSVLESLEKIENITLDRQSGSQLNLSQDINDLSFKVESDFMEQSFVSDNSKGGENHDIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVGKQVDLGNNKPCFEESDSKFNGQETNKVLNESLSQTPPPISVPIDANVSTHNNTHRIAGLDLLAAVAENCSKNDVTEHRSPLPPNKRYLQENPQCKINENDPPQITIDSPIPESVEKIMSNCDQNSIFNFCNISLANXXXXXXXXXXXXXXXXXXXXTENSARLPXXXXXXXXXXXXXAPLSCPSMSMLTNDQFNILFPRNITQTSISPLAKQYTPKTIKTQWIPSCVXXXXXXXXXXKSVPIVSGTETKKKLHLIKDSVSSQTVKLKSPEMDXXXXXXXXXXXXXXFSHHILKPVSVSSQTHENNANVPVQKSTKILLEAKVNAXXXXXXXXXXXXXXXXFRMLRQNLISQDDNNNNVSIHSNLSKPNTLIDSVDKLSPLIRVYSVGQICSPISVNKSIAVAHNHNQSFILIPAKLSTSPYIDRVNSPKAYNXXXXXXXXXXXXXXXXXXHQQIDSKVKPTXXXXXXXXXXQLNNHVNXXXXXXXXXXXXXXXXNIGAKIKFKPPPLQLSTEIMTSPPKSASCVCTTDMLSANPKKKSASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRY 5015
            PELDKGPPNDDYKSNDEGNDDDNANGGVAHWYQLLPILQNCPSVLESLEKIENITLDRQSGSQLNLSQDINDLSFKVESDFMEQSFVSDNSKGGENHDIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVGKQVDLGNNKPCFEESDSKFNGQETNKVLNESLSQTPPPISVPIDANVSTHNNTHRIAGLDLLAAVAENCSKNDVTEHRSPLPPNKRYLQENPQCKINENDPPQITI                                                   ENSARLPITIITTDSINTSTAPLSCPSMSMLTNDQFNILFPRNITQTSISPLAKQYTPKTIKTQWIPSCVQSSLLNLSQNKSVPIVSGTETKKKLHLIKDSVSSQTVKLKSPEMDKKNIKKPNSNSNSSFSHHILKPVSVSSQTHENNANVPVQKSTKILLEAKVNANSLQKSQLQLNQNGNSFRMLRQNLISQDDNNNNVSIHSNLSKPNTLIDSVDKLSPLIRVYSVGQICSPISVNKSIAVAHNH+QSFILIPAKLSTSPYIDRVNSPKAYNSSPV+ISSPSTDSISVSIHQQIDSKVKPT SIAASSAIAQLNNHVNSSTVTSLTSSSSPLSLNIGAKIKFKPPPLQLSTEIMTSPPKSASCVCTTDMLSANPKKKSASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPT      Y
Sbjct:   63 PELDKGPPNDDYKSNDEGNDDDNANGGVAHWYQLLPILQNCPSVLESLEKIENITLDRQSGSQLNLSQDINDLSFKVESDFMEQSFVSDNSKGGENHDIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVGKQVDLGNNKPCFEESDSKFNGQETNKVLNESLSQTPPPISVPIDANVSTHNNTHRIAGLDLLAAVAENCSKNDVTEHRSPLPPNKRYLQENPQCKINENDPPQITI---------------------------------------------------ENSARLPITIITTDSINTSTAPLSCPSMSMLTNDQFNILFPRNITQTSISPLAKQYTPKTIKTQWIPSCVQSSLLNLSQNKSVPIVSGTETKKKLHLIKDSVSSQTVKLKSPEMDKKNIKKPNSNSNSSFSHHILKPVSVSSQTHENNANVPVQKSTKILLEAKVNANSLQKSQLQLNQNGNSFRMLRQNLISQDDNNNNVSIHSNLSKPNTLIDSVDKLSPLIRVYSVGQICSPISVNKSIAVAHNHSQSFILIPAKLSTSPYIDRVNSPKAYNSSPVIISSPSTDSISVSIHQQIDSKVKPTNSIAASSAIAQLNNHVNSSTVTSLTSSSSPLSLNIGAKIKFKPPPLQLSTEIMTSPPKSASCVCTTDMLSANPKKKSASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTGNNYEFY 973
[Close]
BLAST of HMG box domain-containing protein vs. Planmine SMEST
Match: SMESG000017541.1 (SMESG000017541.1)

HSP 1 Score: 1560.43 bits (4039), Expect = 0.000e+0
Identity = 902/962 (93.76%), Postives = 904/962 (93.97%), Query Frame = 3 
Query: 2130 PELDKGPPNDDYKSXXXXXXXXXXXXXVAHWYQLLPILQNCPSVLESLEKIENITLDRQSGSQLNLSQDINDLSFKVESDFMEQSFVSDNSKGGENHDIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVGKQVDLGNNKPCFEESDSKFNGQETNKVLNESLSQTPPPISVPIDANVSTHNNTHRIAGLDLLAAVAENCSKNDVTEHRSPLPPNKRYLQENPQCKINENDPPQITIDSPIPESVEKIMSNCDQNSIFNFCNISLANXXXXXXXXXXXXXXXXXXXXTENSARLPXXXXXXXXXXXXXAPLSCPSMSMLTNDQFNILFPRNITQTSISPLAKQYTPKTIKTQWIPSCVXXXXXXXXXXKSVPIVSGTETKKKLHLIKDSVSSQTVKLKSPEMDXXXXXXXXXXXXXXFSHHILKPVSVSSQTHENNANVPVQKSTKILLEAKVNAXXXXXXXXXXXXXXXXFRMLRQNLISQDDNNNNVSIHSNLSKPNTLIDSVDKLSPLIRVYSVGQICSPISVNKSIAVAHNHNQSFILIPAKLSTSPYIDRVNSPKAYNXXXXXXXXXXXXXXXXXXHQQIDSKVKPTXXXXXXXXXXQLNNHVNXXXXXXXXXXXXXXXXNIGAKIKFKPPPLQLSTEIMTSPPKSASCVCTTDMLSANPKKKSASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTAETVSRY 5015
            PELDKGPPNDDYKSNDEGNDDDNANGGVAHWYQLLPILQNCPSVLESLEKIENITLDRQSGSQLNLSQDINDLSFKVESDFMEQSFVSDNSKGGENHDIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVGKQVDLGNNKPCFEESDSKFNGQETNKVLNESLSQTPPPISVPIDANVSTHNNTHRIAGLDLLAAVAENCSKNDVTEHRSPLPPNKRYLQENPQCKINENDPPQITI                                                   ENSARLPITIITTDSINTSTAPLSCPSMSMLTNDQFNILFPRNITQTSISPLAKQYTPKTIKTQWIPSCVQSSLLNLSQNKSVPIVSGTETKKKLHLIKDSVSSQTVKLKSPEMDKKNIKKPNSNSNSSFSHHILKPVSVSSQTHENNANVPVQKSTKILLEAKVNANSLQKSQLQLNQNGNSFRMLRQNLISQDDNNNNVSIHSNLSKPNTLIDSVDKLSPLIRVYSVGQICSPISVNKSIAVAHNH+QSFILIPAKLSTSPYIDRVNSPKAYNSSPV+ISSPSTDSISVSIHQQIDSKVKPT SIAASSAIAQLNNHVNSSTVTSLTSSSSPLSLNIGAKIKFKPPPLQLSTEIMTSPPKSASCVCTTDMLSANPKKKSASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPT      Y
Sbjct:   22 PELDKGPPNDDYKSNDEGNDDDNANGGVAHWYQLLPILQNCPSVLESLEKIENITLDRQSGSQLNLSQDINDLSFKVESDFMEQSFVSDNSKGGENHDIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVGKQVDLGNNKPCFEESDSKFNGQETNKVLNESLSQTPPPISVPIDANVSTHNNTHRIAGLDLLAAVAENCSKNDVTEHRSPLPPNKRYLQENPQCKINENDPPQITI---------------------------------------------------ENSARLPITIITTDSINTSTAPLSCPSMSMLTNDQFNILFPRNITQTSISPLAKQYTPKTIKTQWIPSCVQSSLLNLSQNKSVPIVSGTETKKKLHLIKDSVSSQTVKLKSPEMDKKNIKKPNSNSNSSFSHHILKPVSVSSQTHENNANVPVQKSTKILLEAKVNANSLQKSQLQLNQNGNSFRMLRQNLISQDDNNNNVSIHSNLSKPNTLIDSVDKLSPLIRVYSVGQICSPISVNKSIAVAHNHSQSFILIPAKLSTSPYIDRVNSPKAYNSSPVIISSPSTDSISVSIHQQIDSKVKPTNSIAASSAIAQLNNHVNSSTVTSLTSSSSPLSLNIGAKIKFKPPPLQLSTEIMTSPPKSASCVCTTDMLSANPKKKSASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPESINDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNHKLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLSPNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTGNNYEFY 932
[Close]
BLAST of HMG box domain-containing protein vs. Planmine SMEST
Match: SMESG000017558.1 (SMESG000017558.1)

HSP 1 Score: 1536.55 bits (3977), Expect = 0.000e+0
Identity = 787/789 (99.75%), Postives = 789/789 (100.00%), Query Frame = 3 
Query:  504 ELNVNTVNKSNTESDKKENVDSFDKDSSLPLKKRKKDTSMKINNSKNVRETELKAAINLLNLSDWHKLPVLLRMENKSIVSYNRATIILSNNNDATVSVQLNSHSASCDNPDSCDINLVDLDQNYPLLIADTPPSIAQLTDKARICYHTSDGTFRCGTITNKTDGDSSTSNQIRNSSRLYTIIPENSSNTTQPEYQKCSRAQLRILKLPWQEELDELLTALKMEYEDDVCENPVIALVTKYTESQGFEEMSTSKSDSDVNFEVKVENFEKQFVESESFTSSNLLSDIPTVPKINDGTPRNSSSSVFNATNLITSGSNQESVIGIFNAEPDHNMVATNTNRSLILSEVGSAIGHKKSFQLSDKMDRNNSSNSLRSFGGCNLQSQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITPGPSFNGHPSLFLSRDSNAGVDMNKINRTRPFPTFDSGSLSKKDDHDYPTPLDLLPILSDSEENEICDDELXXXXXXXXXXXXXXXXXXXXXXXXPELDKGPPNDDYKSXXXXXXXXXXXXXVAHWYQLLPILQNCPSVLESLEKIENITLDRQSGSQLNLSQDINDLSFKVESDFMEQSFVSDNSKGGENHDIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVGKQVDLGNNKPCFEES 2870
            ELNVNTVNKSNTESDKKENVDSFDKDSSLPLKKRKKDTSMKINN+KNVRETELKAAINLLNLSDWHKLPVLLRMENKSIVSYNRATIILSNNNDATVSVQLNSHSASCDNPDSCDINLVDLDQNYPLLIADTPPSIAQLTDKARICYHTSDGTFRCGTITNKTDGDSSTSNQIRNSSRLYTIIPENSSNTTQPEYQKCSRAQLRILKLPWQEELDELLTALKMEY+DDVCENPVIALVTKYTESQGFEEMSTSKSDSDVNFEVKVENFEKQFVESESFTSSNLLSDIPTVPKINDGTPRNSSSSVFNATNLITSGSNQESVIGIFNAEPDHNMVATNTNRSLILSEVGSAIGHKKSFQLSDKMDRNNSSNSLRSFGGCNLQSQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITPGPSFNGHPSLFLSRDSNAGVDMNKINRTRPFPTFDSGSLSKKDDHDYPTPLDLLPILSDSEENEICDDELENKKTDDKDSDNDEDGKDNGDKNNPELDKGPPNDDYKSNDEGNDDDNANGGVAHWYQLLPILQNCPSVLESLEKIENITLDRQSGSQLNLSQDINDLSFKVESDFMEQSFVSDNSKGGENHDIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVGKQVDLGNNKPCFEES
Sbjct:    2 ELNVNTVNKSNTESDKKENVDSFDKDSSLPLKKRKKDTSMKINNAKNVRETELKAAINLLNLSDWHKLPVLLRMENKSIVSYNRATIILSNNNDATVSVQLNSHSASCDNPDSCDINLVDLDQNYPLLIADTPPSIAQLTDKARICYHTSDGTFRCGTITNKTDGDSSTSNQIRNSSRLYTIIPENSSNTTQPEYQKCSRAQLRILKLPWQEELDELLTALKMEYDDDVCENPVIALVTKYTESQGFEEMSTSKSDSDVNFEVKVENFEKQFVESESFTSSNLLSDIPTVPKINDGTPRNSSSSVFNATNLITSGSNQESVIGIFNAEPDHNMVATNTNRSLILSEVGSAIGHKKSFQLSDKMDRNNSSNSLRSFGGCNLQSQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITPGPSFNGHPSLFLSRDSNAGVDMNKINRTRPFPTFDSGSLSKKDDHDYPTPLDLLPILSDSEENEICDDELENKKTDDKDSDNDEDGKDNGDKNNPELDKGPPNDDYKSNDEGNDDDNANGGVAHWYQLLPILQNCPSVLESLEKIENITLDRQSGSQLNLSQDINDLSFKVESDFMEQSFVSDNSKGGENHDIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPGWKWSSLKHGRSKFSNSYEDTENKEVGKQVDLGNNKPCFEES 790
[Close]
BLAST of HMG box domain-containing protein vs. Planmine SMEST
Match: SMESG000017558.1 (SMESG000017558.1)

HSP 1 Score: 1425.22 bits (3688), Expect = 0.000e+0
Identity = 735/738 (99.59%), Postives = 738/738 (100.00%), Query Frame = 3 
Query:  504 ELNVNTVNKSNTESDKKENVDSFDKDSSLPLKKRKKDTSMKINNSKNVRETELKAAINLLNLSDWHKLPVLLRMENKSIVSYNRATIILSNNNDATVSVQLNSHSASCDNPDSCDINLVDLDQNYPLLIADTPPSIAQLTDKARICYHTSDGTFRCGTITNKTDGDSSTSNQIRNSSRLYTIIPENSSNTTQPEYQKCSRAQLRILKLPWQEELDELLTALKMEYEDDVCENPVIALVTKYTESQGFEEMSTSKSDSDVNFEVKVENFEKQFVESESFTSSNLLSDIPTVPKINDGTPRNSSSSVFNATNLITSGSNQESVIGIFNAEPDHNMVATNTNRSLILSEVGSAIGHKKSFQLSDKMDRNNSSNSLRSFGGCNLQSQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITPGPSFNGHPSLFLSRDSNAGVDMNKINRTRPFPTFDSGSLSKKDDHDYPTPLDLLPILSDSEENEICDDELXXXXXXXXXXXXXXXXXXXXXXXXPELDKGPPNDDYKSXXXXXXXXXXXXXVAHWYQLLPILQNCPSVLESLEKIENITLDRQSGSQLNLSQDINDLSFKVESDFMEQSFVSDNSKGGENHDIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQL 2717
            ELNVNTVNKSNTESDKKENVDSFDKDSSLPLKKRKKDTSMKINN+KNVRETELKAAINLLNLSDWHKLPVLLRMENKSIVSYNRATIILSNNNDATVSVQLNSHSASCDNPDSCDINLVDLDQNYPLLIADTPPSIAQLTDKARICYHTSDGTFRCGTITNKTDGDSSTSNQIRNSSRLYTIIPENSSNTTQPEYQKCSRAQLRILKLPWQEELDELLTALKMEY+DDVCENPVIALVTKYTESQGFEEMSTSKSDSDVNFEVKVENFEKQFVESESFTSSNLLSDIPTVPKINDGTPRNSSSSVFNATNLITSGSNQESVIGIFNAEPDHNMVATNTNRSLILSEVGSAIGHKKSFQLSDKMDRNNSSNSLRSFGGCNLQSQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITPGPSFNGHPSLFLSRDSNAGVDMNKINRTRPFPTFDSGSLSKKDDHDYPTPLDLLPILSDSEENEICDDELENKKTDDKDSDNDEDGKDNGDKNNPELDKGPPNDDYKSNDEGNDDDNANGGVAHWYQLLPILQNCPSVLESLEKIENITLDRQSGSQLNLSQDINDLSFKVESDFMEQSFVSDNSKGGENHDIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQ+
Sbjct:    2 ELNVNTVNKSNTESDKKENVDSFDKDSSLPLKKRKKDTSMKINNAKNVRETELKAAINLLNLSDWHKLPVLLRMENKSIVSYNRATIILSNNNDATVSVQLNSHSASCDNPDSCDINLVDLDQNYPLLIADTPPSIAQLTDKARICYHTSDGTFRCGTITNKTDGDSSTSNQIRNSSRLYTIIPENSSNTTQPEYQKCSRAQLRILKLPWQEELDELLTALKMEYDDDVCENPVIALVTKYTESQGFEEMSTSKSDSDVNFEVKVENFEKQFVESESFTSSNLLSDIPTVPKINDGTPRNSSSSVFNATNLITSGSNQESVIGIFNAEPDHNMVATNTNRSLILSEVGSAIGHKKSFQLSDKMDRNNSSNSLRSFGGCNLQSQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITPGPSFNGHPSLFLSRDSNAGVDMNKINRTRPFPTFDSGSLSKKDDHDYPTPLDLLPILSDSEENEICDDELENKKTDDKDSDNDEDGKDNGDKNNPELDKGPPNDDYKSNDEGNDDDNANGGVAHWYQLLPILQNCPSVLESLEKIENITLDRQSGSQLNLSQDINDLSFKVESDFMEQSFVSDNSKGGENHDIVKQSEMDSFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRGEVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQV 739
[Close]
BLAST of HMG box domain-containing protein vs. Planmine SMEST
Match: SMESG000017543.1 (SMESG000017543.1)

HSP 1 Score: 994.956 bits (2571), Expect = 0.000e+0
Identity = 486/490 (99.18%), Postives = 488/490 (99.59%), Query Frame = 3 
Query:  504 ELNVNTVNKSNTESDKKENVDSFDKDSSLPLKKRKKDTSMKINNSKNVRETELKAAINLLNLSDWHKLPVLLRMENKSIVSYNRATIILSNNNDATVSVQLNSHSASCDNPDSCDINLVDLDQNYPLLIADTPPSIAQLTDKARICYHTSDGTFRCGTITNKTDGDSSTSNQIRNSSRLYTIIPENSSNTTQPEYQKCSRAQLRILKLPWQEELDELLTALKMEYEDDVCENPVIALVTKYTESQGFEEMSTSKSDSDVNFEVKVENFEKQFVESESFTSSNLLSDIPTVPKINDGTPRNSSSSVFNATNLITSGSNQESVIGIFNAEPDHNMVATNTNRSLILSEVGSAIGHKKSFQLSDKMDRNNSSNSLRSFGGCNLQSQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITPGPSFNGHPSLFLSRDSNAGVDMNKINRTRPFPTFDSGSLSKK 1973
            ELNVNTVNKSNTESDKKENVDSFDKDSSLPLKKRKKDTSMKINN+KNVRETELKAAINLLNLSDWHKLPVLLRMENKSIVSYNRATIILSNNNDATVSVQLNSHSASCDNPDSCDINLVDLDQNYPLLIADTPPSIAQLTDKARICYHTSDGTFRCGTITNKTDGDSSTSNQIRNSSRLYTIIPENSSNTTQPEYQKCSRAQLRILKLPWQEELDELLTALKMEYEDDVCENPVIALVTKYTESQGFEEM  SKSDSDVNFEVKVENFEKQFVESESFTSSNLLSDIPTVPKINDGTPRNSSSS+FNATNLITSGSNQESVIGIFNAEPDHNMVATNTNRSLILSEVGSAIGHKKSFQLSDKMDRNNSSNSLRSFGGCNLQSQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITPGPSFNGHPSLFLSRDSNAGVDMNKINRTRPFPTFDSGSLSKK
Sbjct:    2 ELNVNTVNKSNTESDKKENVDSFDKDSSLPLKKRKKDTSMKINNAKNVRETELKAAINLLNLSDWHKLPVLLRMENKSIVSYNRATIILSNNNDATVSVQLNSHSASCDNPDSCDINLVDLDQNYPLLIADTPPSIAQLTDKARICYHTSDGTFRCGTITNKTDGDSSTSNQIRNSSRLYTIIPENSSNTTQPEYQKCSRAQLRILKLPWQEELDELLTALKMEYEDDVCENPVIALVTKYTESQGFEEMPISKSDSDVNFEVKVENFEKQFVESESFTSSNLLSDIPTVPKINDGTPRNSSSSIFNATNLITSGSNQESVIGIFNAEPDHNMVATNTNRSLILSEVGSAIGHKKSFQLSDKMDRNNSSNSLRSFGGCNLQSQKCYRKGDVVKTPNGVRKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITPGPSFNGHPSLFLSRDSNAGVDMNKINRTRPFPTFDSGSLSKK 491
The following BLAST results are available for this feature:
BLAST of HMG box domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CIC3.889e-2158.97capicua transcriptional repressor [Source:HGNC Sym... [more]
CIC1.529e-2058.97capicua transcriptional repressor [Source:HGNC Sym... [more]
CIC1.554e-2058.97capicua transcriptional repressor [Source:HGNC Sym... [more]
BBX6.265e-1636.61BBX high mobility group box domain containing [Sou... [more]
BBX1.314e-1536.61BBX high mobility group box domain containing [Sou... [more]
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BLAST of HMG box domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gei-36.402e-2764.86GEX Interacting protein [Source:UniProtKB/TrEMBL;... [more]
gei-39.050e-2764.86GEX Interacting protein [Source:UniProtKB/TrEMBL;... [more]
sox-42.535e-1132.69SOX (Mammalian SRY box) family [Source:UniProtKB/... [more]
sox-43.509e-1133.01SOX (Mammalian SRY box) family [Source:UniProtKB/... [more]
gei-31.300e-1029.36GEX Interacting protein [Source:UniProtKB/TrEMBL;... [more]
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BLAST of HMG box domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cic4.764e-2454.26gene:FBgn0262582 transcript:FBtr0305027[more]
cic5.604e-2454.26gene:FBgn0262582 transcript:FBtr0334306[more]
cic6.040e-2455.95gene:FBgn0262582 transcript:FBtr0305029[more]
cic6.287e-2454.26gene:FBgn0262582 transcript:FBtr0305026[more]
cic6.290e-2454.26gene:FBgn0262582 transcript:FBtr0305028[more]
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BLAST of HMG box domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cica3.245e-2560.24capicua transcriptional repressor a [Source:ZFIN;A... [more]
cicb1.104e-2464.29capicua transcriptional repressor b [Source:ZFIN;A... [more]
cicb1.153e-2162.12capicua transcriptional repressor b [Source:ZFIN;A... [more]
bbx1.102e-1545.07BBX high mobility group box domain containing [Sou... [more]
bbx1.964e-1545.07BBX high mobility group box domain containing [Sou... [more]
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BLAST of HMG box domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lrrc4b1.723e-2464.29leucine rich repeat containing 4B [Source:Xenbase;... [more]
prtfdc14.502e-1545.07phosphoribosyl transferase domain containing 1 [So... [more]
sox71.777e-1134.23SRY-box 7 [Source:NCBI gene;Acc:549080][more]
wasf13.240e-1139.47WASP family member 1 [Source:Xenbase;Acc:XB-GENE-9... [more]
wasf13.454e-1139.47WASP family member 1 [Source:Xenbase;Acc:XB-GENE-9... [more]
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BLAST of HMG box domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cic1.023e-2464.29capicua transcriptional repressor [Source:MGI Symb... [more]
Cic3.003e-2158.97capicua transcriptional repressor [Source:MGI Symb... [more]
Cic8.859e-2158.97capicua transcriptional repressor [Source:MGI Symb... [more]
Cic9.477e-2158.97capicua transcriptional repressor [Source:MGI Symb... [more]
Bbx1.159e-1536.61bobby sox HMG box containing [Source:MGI Symbol;Ac... [more]
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BLAST of HMG box domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9U1H0|CIC_DROME4.776e-2354.26Putative transcription factor capicua OS=Drosophil... [more]
sp|Q924A2|CIC_MOUSE2.100e-2058.97Protein capicua homolog OS=Mus musculus OX=10090 G... [more]
sp|Q96RK0|CIC_HUMAN7.342e-2058.97Protein capicua homolog OS=Homo sapiens OX=9606 GN... [more]
sp|Q8VBW5|BBX_MOUSE1.035e-1436.61HMG box transcription factor BBX OS=Mus musculus O... [more]
sp|Q8WY36|BBX_HUMAN3.034e-1445.07HMG box transcription factor BBX OS=Homo sapiens O... [more]
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BLAST of HMG box domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5J4NGF45.878e-3130.68HMG box domain-containing protein (Fragment) OS=Pa... [more]
A0A183B8194.890e-2948.51HMG box domain-containing protein OS=Echinostoma c... [more]
A0A4Z2D9N92.736e-2841.92Protein capicua OS=Schistosoma japonicum OX=6182 G... [more]
A0A3R7JLF43.916e-2828.92Protein capicua-like protein (Fragment) OS=Clonorc... [more]
A0A183KNU81.366e-2756.31HMG box domain-containing protein OS=Schistosoma c... [more]
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BLAST of HMG box domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cica5.711e-2560.24capicua transcriptional repressor a [Source:ZFIN;A... [more]
cicb1.220e-2464.29capicua transcriptional repressor b [Source:ZFIN;A... [more]
bbx9.027e-1645.07BBX high mobility group box domain containing [Sou... [more]
bbx9.027e-1645.07BBX high mobility group box domain containing [Sou... [more]
bbx9.027e-1645.07BBX high mobility group box domain containing [Sou... [more]
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BLAST of HMG box domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000008165.15.265e-1240.28pep scaffold:Pmarinus_7.0:GL479973:18969:29522:-1 ... [more]
sox128.605e-1134.62SRY-box transcription factor 12 [Source:ZFIN;Acc:Z... [more]
hbp11.055e-1046.84HMG-box transcription factor 1 [Source:ZFIN;Acc:ZD... [more]
sox4b2.654e-1036.36SRY-box transcription factor 4b [Source:ZFIN;Acc:Z... [more]
ENSPMAT00000010223.11.612e-933.33pep scaffold:Pmarinus_7.0:GL478813:2555:9375:-1 ge... [more]
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BLAST of HMG box domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HMG box domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO353731.377e-1861.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO361443.656e-1246.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO377196.075e-1140.58Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO441426.089e-1129.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO387552.547e-1037.14Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of HMG box domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cica9.293e-2647.57protein capicua homolog [Source:NCBI gene;Acc:1011... [more]
cicb6.307e-2564.29capicua transcriptional repressor [Source:NCBI gen... [more]
cicb6.724e-2564.29capicua transcriptional repressor [Source:NCBI gen... [more]
cicb6.724e-2564.29capicua transcriptional repressor [Source:NCBI gen... [more]
cicb1.713e-2464.29capicua transcriptional repressor [Source:NCBI gen... [more]
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BLAST of HMG box domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000017541.10.000e+093.76SMESG000017541.1[more]
SMESG000017541.10.000e+093.76SMESG000017541.1[more]
SMESG000017558.10.000e+099.75SMESG000017558.1[more]
SMESG000017558.10.000e+099.59SMESG000017558.1[more]
SMESG000017543.10.000e+099.18SMESG000017543.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30003094 ID=SMED30003094|Name=HMG box domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=5665bp
TTTTAGAATAATTATTTAAATATCAAAATGACTTTAAATATAACTTTGAA
TATTTGTGTTGACTAATAAATAAAATATTCATATACAACTGTGGTTCCCG
GGGGTTGGTGGTGATTTGTGTGGTTTACGTCGGATTTCAAAAATGAACTT
CAAATCTATTGTATTTTAAAAAGTTTATTGTTGTGTAACATTTTTTAACC
CTTGAAAAAAGTTAATGATATCTAATCAGTGACTTTTAATACTAAGATAA
GAAGTTAATTGCAAGACAATTTTTTGTTTATAATAATGGCTTGTTGATCT
TTGTGATTGTTGAATCGCTACCAAAAATGATCCTATGCTTTACTAGAAAT
ATGACCTTGATTATTGATTACATACAATTGTTAAACTATTAAGACTTAAT
TTTAAATCGACCAATAAGAATTTACAATATATTCTTTGTGGTGTATTGAT
TTTATTATTTTGTATATTGCGTATTAAAGTGGTTGTAAACATTCTTTATG
TATGAATTGAATGTTAATACAGTAAATAAAAGCAATACAGAATCGGATAA
AAAAGAAAATGTTGATTCATTTGATAAAGATTCTTCCTTGCCATTAAAGA
AGCGTAAAAAAGATACCAGTATGAAAATAAATAATTCAAAGAATGTTAGG
GAAACAGAATTAAAAGCTGCAATTAATCTACTAAATCTTTCTGATTGGCA
TAAGTTACCGGTCTTATTGAGAATGGAAAATAAATCTATTGTATCATATA
ATCGAGCAACAATTATTCTTTCAAATAACAACGATGCCACAGTATCAGTT
CAGCTAAATTCTCATTCAGCTTCATGTGACAATCCAGATTCGTGCGATAT
AAATCTGGTTGATCTTGATCAAAACTATCCCCTGCTTATTGCGGACACAC
CTCCGTCAATTGCACAGTTAACTGACAAAGCTCGTATTTGCTATCATACT
TCAGATGGTACTTTTCGATGTGGTACAATCACCAATAAAACTGACGGTGA
TTCTTCCACTAGCAACCAAATACGAAATAGCTCTCGTCTTTACACAATTA
TTCCTGAAAATTCATCCAATACAACACAACCTGAATATCAAAAATGTTCA
AGGGCTCAACTCAGAATTCTCAAACTGCCCTGGCAGGAAGAATTGGACGA
GTTATTGACTGCGCTAAAAATGGAATATGAAGACGATGTATGTGAAAATC
CTGTTATTGCACTTGTAACAAAATATACAGAATCACAAGGTTTTGAGGAA
ATGTCAACATCGAAATCTGATTCGGATGTGAATTTTGAGGTTAAAGTGGA
AAATTTTGAAAAACAATTTGTGGAATCAGAATCGTTTACTAGTTCGAACT
TATTATCAGATATACCCACAGTTCCAAAGATAAACGATGGAACTCCACGC
AACAGTTCCAGTTCTGTTTTTAATGCGACTAATCTCATAACATCTGGAAG
CAATCAAGAATCTGTCATAGGGATATTTAACGCTGAACCCGATCATAATA
TGGTTGCCACAAATACAAACAGGTCACTGATTCTTAGTGAAGTTGGTAGC
GCTATAGGACACAAAAAGTCCTTTCAATTAAGTGATAAAATGGACAGGAA
TAATTCATCGAATTCTTTGAGATCATTTGGTGGCTGCAATTTACAATCAC
AAAAGTGCTATAGAAAAGGTGATGTAGTAAAGACACCAAATGGAGTTCGG
AAAAAGTTTAACGGTAAACAGTGGCGCAGATTATGCAGTAAAGAAAATTG
TACCAAAGAATCTCAAAGAAGAGGATTTTGTTCAAGACATTTATCTATGA
GAGGTAAGGAAATTAGATCATCACTTACTAATCTTGGAATTACTCCAGGG
CCCTCTTTCAATGGTCATCCGTCATTGTTTTTATCTCGAGATTCAAATGC
TGGGGTTGATATGAATAAAATAAATCGAACAAGACCATTTCCAACTTTTG
ATAGTGGATCTTTATCAAAAAAAGATGATCATGATTATCCTACTCCTCTT
GATTTATTACCAATATTGTCGGATTCTGAGGAAAACGAAATTTGTGATGA
TGAATTAGAAAACAAGAAAACTGATGACAAAGATAGTGATAACGATGAGG
ATGGCAAGGACAATGGAGACAAAAATAATCCCGAATTAGATAAAGGTCCT
CCAAATGATGATTACAAATCAAATGATGAAGGCAATGATGATGACAATGC
TAATGGAGGTGTGGCTCATTGGTATCAGTTATTGCCAATTTTACAGAACT
GTCCATCAGTTTTAGAGTCTTTGGAAAAAATTGAAAATATAACTTTAGAT
AGACAAAGTGGATCTCAACTCAATTTATCTCAAGATATAAATGATCTGTC
TTTTAAAGTTGAATCAGATTTTATGGAGCAATCATTCGTGTCTGATAATA
GTAAAGGGGGCGAAAATCATGATATTGTAAAGCAGTCTGAAATGGATTCA
TTCCAACAGGACACTAAAACCAACGAATCCAATAACAAAGAATCTAAACA
ATCTATTATAAGATCTCCAACACAGCACGGGTTTATGGGCCCCCGCATTC
GACGACCGATGAATGCATTTATGATATTTTCAATGCGTCACCGGGGGGAA
GTTCATAAACAAAATCCAAACAAAGATAATCGGGCAGTAAGTCAAATCCT
CGGTGAGTGGTGGTATCAAATGAGCAATGTTGAAAAAGAGCCTTACCAAA
AATTAGCCCAACAATTAAAAGATGCTCATTTTCGAAATTATCCCGGTTGG
AAATGGTCATCTCTAAAACATGGCAGATCAAAGTTTTCTAATAGTTATGA
GGATACAGAAAATAAAGAAGTTGGGAAACAAGTTGATCTAGGAAATAATA
AACCATGTTTTGAAGAATCAGATTCTAAATTTAATGGCCAAGAAACTAAT
AAGGTTTTGAACGAGTCACTTAGCCAAACCCCTCCTCCAATTAGTGTCCC
GATAGATGCCAATGTGAGTACTCATAATAACACGCACAGAATCGCAGGTC
TTGATCTTTTGGCAGCGGTAGCTGAAAACTGTAGTAAAAATGATGTAACG
GAACATCGATCTCCATTGCCACCAAATAAACGGTATTTACAAGAAAATCC
TCAATGCAAAATTAACGAGAATGATCCACCTCAAATTACAATAGATTCAC
CAATTCCGGAATCAGTTGAAAAAATCATGTCAAATTGTGATCAAAATTCA
ATATTCAATTTCTGTAACATTTCATTGGCTAATTCTGTTTCACCCCTTTC
AAACGGATCTATTTTATCGTCTTCTTTATTAAGTGCACTTTCCACAGAGA
ATAGTGCTAGACTGCCTATCACTATAATAACTACCGATTCGATTAATACA
TCTACAGCTCCACTTTCTTGCCCGTCGATGTCAATGCTTACTAATGATCA
GTTTAATATTTTATTTCCGAGAAATATTACTCAAACTTCCATTAGTCCGT
TAGCTAAACAATATACTCCTAAAACAATAAAAACTCAATGGATTCCCTCT
TGTGTTCAGTCATCTCTACTCAATTTGTCACAAAATAAATCCGTGCCTAT
TGTTAGTGGTACTGAAACAAAAAAGAAATTACATTTGATTAAAGATTCGG
TTTCATCTCAAACTGTGAAATTAAAATCTCCTGAGATGGATAAAAAGAAT
ATTAAAAAGCCAAATTCCAATTCCAACTCTTCATTCAGTCATCATATACT
AAAACCAGTCTCAGTTTCATCGCAAACACATGAAAATAATGCCAATGTTC
CAGTACAAAAGTCGACTAAAATCCTTCTTGAAGCAAAGGTCAATGCAAAT
TCATTACAAAAATCTCAGTTACAGCTTAATCAAAACGGAAATTCATTTCG
AATGTTAAGACAAAATTTAATTTCTCAAGATGATAATAATAATAATGTTT
CTATACATTCTAATCTTTCCAAACCGAATACTTTGATTGATTCGGTTGAC
AAATTGTCACCTCTAATCCGGGTGTATTCTGTCGGGCAAATTTGCAGTCC
AATATCAGTTAACAAATCAATCGCTGTTGCTCATAATCACAATCAATCAT
TTATCCTAATTCCAGCAAAATTATCAACTTCACCTTATATTGATCGTGTT
AATTCACCCAAAGCTTATAATTCCTCTCCAGTTGTTATTTCTTCTCCATC
GACCGATTCAATATCTGTCAGTATTCACCAACAAATTGACAGCAAAGTAA
AGCCGACAATCTCGATTGCTGCCTCATCAGCAATAGCTCAATTGAATAAT
CACGTTAATTCATCCACTGTTACTTCTCTGACATCTTCTTCATCACCTTT
ATCTTTGAACATCGGCGCGAAAATTAAATTCAAACCCCCTCCTCTTCAAT
TGAGCACAGAAATAATGACTTCTCCTCCAAAATCTGCTTCTTGTGTATGT
ACAACAGACATGCTCAGTGCTAATCCTAAAAAGAAATCTGCTTCTGCACT
TTTTAAGAGAAAACTCGATGAAGACACTGAAAATGTCCTTGCGGAAGTGG
ATTTCCAGAGAAAATTCATTGATTTACCACAGTTTAATCCAGAGTCCATC
AATGATAATGTAGCACAGTCTCCGAGGGTCATCAATATCAAGAATTTAAC
CAATATTCCGGAATGTTTAACTGCTGATCATGGATGTAAACCTCGAATTT
TAAAAAGACCTTTGACTCCTGGAAATCAGAATGAAGAACCGAATCATAAA
CTTCCGAAATCGGCTGATGTTGCTACTTTACGTAGTAGATTTATGTCTGA
TACAAATAACATATTTTTTGGTTCCGATTTCCCATTAACTATAAATAGTG
GATCTGGATATAGCGGTACCAATTCTATCGCAAACACTCCACTCAGTCCG
AATTTTTTGGCCAATGGCAATAAAGCGTCGCCGTTATTAACGCCAAATGG
TTCTTTAAATTCCTCAGGTTCTAAAAAGATACTTGAATGCCGAAGAAATT
TTGTCGTAAAATTATTCAAAGAAAATGAAAATCTTTTCCCGACAGCTGAA
ACAGTTAGTCGCTACCAAAAGCAGCATGCAAATGTTTTCCCTAGTATTCA
AATTCTCAAACACAAAATAAGAGAAGTTCGTCAAAAAATTATGCAACAAT
CGAATTTGCCATCTCCTAATAGCAACAGTGGTTCGAAAACTTCTTTGCTT
CATATAGCTTTAGATCCGAACGAAGAGAATAATAAATGCAACATAGACGG
CAAATTAATCCTAACAAATGACTCAAACAACAACCTCGAAATAGCAACCA
AGTACCACCAATCGGACCGGTCAACTCTCATTGAAATGTCTAACAATAAT
GTTCATTTATGCGACACCATCAATTGTACAAATCATTTTTAACGTCATTG
TCAAATGATCTCATTTTTTGTATTAATTAAGTCATCATTTCCATGGATAA
CAATTTTTAATATTGTTCTTTATTTTGTTTTATATATTTTCTCTTCAATT
AACCTCTTACAAAACTTTGTCAGAGATTTGTTAAAATTTTATTCATTTAT
CTTAATTTGTCAATTTTATCTTACTGATAGCCAGACTAATCAACTGAGTG
GTATTAGCTTTTGTTGGATGTTTTCATTAATGCCCGGCGGACATCTCCCG
GTTGATTGTTTACCCTGTTGCTATTATCTTAGTCAGTAATTATATATCAA
GTTCTCTTGAAAAAA
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protein sequence of SMED30003094-orf-1

>SMED30003094-orf-1 ID=SMED30003094-orf-1|Name=SMED30003094-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1615bp
MYELNVNTVNKSNTESDKKENVDSFDKDSSLPLKKRKKDTSMKINNSKNV
RETELKAAINLLNLSDWHKLPVLLRMENKSIVSYNRATIILSNNNDATVS
VQLNSHSASCDNPDSCDINLVDLDQNYPLLIADTPPSIAQLTDKARICYH
TSDGTFRCGTITNKTDGDSSTSNQIRNSSRLYTIIPENSSNTTQPEYQKC
SRAQLRILKLPWQEELDELLTALKMEYEDDVCENPVIALVTKYTESQGFE
EMSTSKSDSDVNFEVKVENFEKQFVESESFTSSNLLSDIPTVPKINDGTP
RNSSSSVFNATNLITSGSNQESVIGIFNAEPDHNMVATNTNRSLILSEVG
SAIGHKKSFQLSDKMDRNNSSNSLRSFGGCNLQSQKCYRKGDVVKTPNGV
RKKFNGKQWRRLCSKENCTKESQRRGFCSRHLSMRGKEIRSSLTNLGITP
GPSFNGHPSLFLSRDSNAGVDMNKINRTRPFPTFDSGSLSKKDDHDYPTP
LDLLPILSDSEENEICDDELENKKTDDKDSDNDEDGKDNGDKNNPELDKG
PPNDDYKSNDEGNDDDNANGGVAHWYQLLPILQNCPSVLESLEKIENITL
DRQSGSQLNLSQDINDLSFKVESDFMEQSFVSDNSKGGENHDIVKQSEMD
SFQQDTKTNESNNKESKQSIIRSPTQHGFMGPRIRRPMNAFMIFSMRHRG
EVHKQNPNKDNRAVSQILGEWWYQMSNVEKEPYQKLAQQLKDAHFRNYPG
WKWSSLKHGRSKFSNSYEDTENKEVGKQVDLGNNKPCFEESDSKFNGQET
NKVLNESLSQTPPPISVPIDANVSTHNNTHRIAGLDLLAAVAENCSKNDV
TEHRSPLPPNKRYLQENPQCKINENDPPQITIDSPIPESVEKIMSNCDQN
SIFNFCNISLANSVSPLSNGSILSSSLLSALSTENSARLPITIITTDSIN
TSTAPLSCPSMSMLTNDQFNILFPRNITQTSISPLAKQYTPKTIKTQWIP
SCVQSSLLNLSQNKSVPIVSGTETKKKLHLIKDSVSSQTVKLKSPEMDKK
NIKKPNSNSNSSFSHHILKPVSVSSQTHENNANVPVQKSTKILLEAKVNA
NSLQKSQLQLNQNGNSFRMLRQNLISQDDNNNNVSIHSNLSKPNTLIDSV
DKLSPLIRVYSVGQICSPISVNKSIAVAHNHNQSFILIPAKLSTSPYIDR
VNSPKAYNSSPVVISSPSTDSISVSIHQQIDSKVKPTISIAASSAIAQLN
NHVNSSTVTSLTSSSSPLSLNIGAKIKFKPPPLQLSTEIMTSPPKSASCV
CTTDMLSANPKKKSASALFKRKLDEDTENVLAEVDFQRKFIDLPQFNPES
INDNVAQSPRVINIKNLTNIPECLTADHGCKPRILKRPLTPGNQNEEPNH
KLPKSADVATLRSRFMSDTNNIFFGSDFPLTINSGSGYSGTNSIANTPLS
PNFLANGNKASPLLTPNGSLNSSGSKKILECRRNFVVKLFKENENLFPTA
ETVSRYQKQHANVFPSIQILKHKIREVRQKIMQQSNLPSPNSNSGSKTSL
LHIALDPNEENNKCNIDGKLILTNDSNNNLEIATKYHQSDRSTLIEMSNN
NVHLCDTINCTNHF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR009071HMG_box_dom
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0043565sequence-specific DNA binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
Vocabulary: biological process
TermDefinition
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
GO:0007275multicellular organism development
GO:0007507heart development
GO:0030178negative regulation of Wnt signaling pathway