Bestrophin homolog
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002988 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Bestrophin homolog vs. Ensembl Human
Match: BEST2 (bestrophin 2 [Source:HGNC Symbol;Acc:HGNC:17107]) HSP 1 Score: 266.929 bits (681), Expect = 4.320e-82 Identity = 141/387 (36.43%), Postives = 222/387 (57.36%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRN-DFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRP-FRGSFCEMRIDNEN 1226
MTV Y V A GF +LL+ W+GSI++L++ + L F FYMA+S +RF+L E KR FE ++ Y + +LIPV+F++GFYV L+ +R+W + +P +V+ + ++ RL +RT++RY S ++ L VS V +RF I+ + G + E E + ++P +W +++ +A + RI + S L ++EE+N FR LF D I VPLVYTQVVT+A+YSYFL+CL+GRQF+ + K+ + D +PIFT+LQF Y GW+K+A L+NP GEDD+DF+ N LID NFQ + +V+ + EKD ++++ + P + F +P F+GS ++ + E+
Sbjct: 1 MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYRFVLTEGQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVA--------------GTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYTQVVTIALYSYFLACLIGRQFLDPAQGYKDHDLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAVLEKDLYWDAAEARAPYTAATVFQLRQPSFQGSTFDITLAKED 373
BLAST of Bestrophin homolog vs. Ensembl Human
Match: BEST2 (bestrophin 2 [Source:HGNC Symbol;Acc:HGNC:17107]) HSP 1 Score: 266.929 bits (681), Expect = 4.320e-82 Identity = 141/387 (36.43%), Postives = 222/387 (57.36%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRN-DFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRP-FRGSFCEMRIDNEN 1226
MTV Y V A GF +LL+ W+GSI++L++ + L F FYMA+S +RF+L E KR FE ++ Y + +LIPV+F++GFYV L+ +R+W + +P +V+ + ++ RL +RT++RY S ++ L VS V +RF I+ + G + E E + ++P +W +++ +A + RI + S L ++EE+N FR LF D I VPLVYTQVVT+A+YSYFL+CL+GRQF+ + K+ + D +PIFT+LQF Y GW+K+A L+NP GEDD+DF+ N LID NFQ + +V+ + EKD ++++ + P + F +P F+GS ++ + E+
Sbjct: 1 MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYRFVLTEGQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVA--------------GTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYTQVVTIALYSYFLACLIGRQFLDPAQGYKDHDLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAVLEKDLYWDAAEARAPYTAATVFQLRQPSFQGSTFDITLAKED 373
BLAST of Bestrophin homolog vs. Ensembl Human
Match: BEST2 (bestrophin 2 [Source:HGNC Symbol;Acc:HGNC:17107]) HSP 1 Score: 266.929 bits (681), Expect = 4.320e-82 Identity = 141/387 (36.43%), Postives = 222/387 (57.36%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRN-DFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRP-FRGSFCEMRIDNEN 1226
MTV Y V A GF +LL+ W+GSI++L++ + L F FYMA+S +RF+L E KR FE ++ Y + +LIPV+F++GFYV L+ +R+W + +P +V+ + ++ RL +RT++RY S ++ L VS V +RF I+ + G + E E + ++P +W +++ +A + RI + S L ++EE+N FR LF D I VPLVYTQVVT+A+YSYFL+CL+GRQF+ + K+ + D +PIFT+LQF Y GW+K+A L+NP GEDD+DF+ N LID NFQ + +V+ + EKD ++++ + P + F +P F+GS ++ + E+
Sbjct: 1 MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYRFVLTEGQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVA--------------GTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYTQVVTIALYSYFLACLIGRQFLDPAQGYKDHDLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAVLEKDLYWDAAEARAPYTAATVFQLRQPSFQGSTFDITLAKED 373
BLAST of Bestrophin homolog vs. Ensembl Human
Match: BEST3 (bestrophin 3 [Source:HGNC Symbol;Acc:HGNC:17105]) HSP 1 Score: 259.61 bits (662), Expect = 1.236e-80 Identity = 133/380 (35.00%), Postives = 212/380 (55.79%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFII-VSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEM 1208
MTV Y V A GF +LL++W+GSI++L+Y +F++FA Y AIS+++R +L KR FE + Y + IPV F++GFYV L+ +R+W F +PW + L+S+ + E RL +RT++RY+ + L+ VS V +RF ++ + G + E L + ++ ++P +W ++ KA ++ RI + L ++ E+N++R LF D + +PLVYTQVVTLA+Y++F +CL+GRQF+ Y + D IPIFT+LQF Y GW+K+A L+NP GEDD+DF+ N ID N Q + +V+ + S P +KD +++ + P + F GS +M
Sbjct: 1 MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKRYFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISS--------------SVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVVTLAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFLGSTVQM 366
BLAST of Bestrophin homolog vs. Ensembl Human
Match: BEST3 (bestrophin 3 [Source:HGNC Symbol;Acc:HGNC:17105]) HSP 1 Score: 262.307 bits (669), Expect = 9.224e-79 Identity = 135/393 (34.35%), Postives = 217/393 (55.22%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFI-IVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRID-----NENWI 1232
MTV Y V A GF +LL++W+GSI++L+Y +F++FA Y AIS+++R +L KR FE + Y + IPV F++GFYV L+ +R+W F +PW + L+S+ + E RL +RT++RY+ + L+ VS V +RF ++ + G + E L + ++ ++P +W ++ KA ++ RI + L ++ E+N++R LF D + +PLVYTQVVTLA+Y++F +CL+GRQF+ Y + D IPIFT+LQF Y GW+K+A L+NP GEDD+DF+ N ID N Q + +V+ + S P +KD +++ + P + F GS +M + +E W+
Sbjct: 1 MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKRYFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISS--------------SVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVVTLAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFLGSTVQMGLSGSDFPDEEWL 379
BLAST of Bestrophin homolog vs. Ensembl Celegans
Match: best-3 (Bestrophin homolog [Source:UniProtKB/TrEMBL;Acc:O17206]) HSP 1 Score: 236.113 bits (601), Expect = 6.935e-70 Identity = 132/408 (32.35%), Postives = 219/408 (53.68%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFII-----VSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNENWIASIKSLLIDKESPDDG 1280
MTV Y DV ++ KLL RWKGSI++ ++++ +++ Y +S+I+R +L + FE + + IP+ F++GFYV+ +F+R+WQ F+ I WI L ++ + IK E E+ + +R IRY + + + V+ V++RF N L G++ E E E + + P+ W S+I A D+ I ++ + + ++E++ +FR + L L D + VPLVYTQVV LA+ SYFL L GRQ++ ++D+ K D +PI ++LQFI +IGW+K+A L+NP+GEDD+DF+ N ++D N Q G+ V+ + P EKD F+ I + +S P GS +M + E ++ + + + S DG
Sbjct: 1 MTVTYSLDVASSSFFCLYKLLFRWKGSIWKSVWAELVVWLCLYAVLSVIYRCLLTMKQRATFEDLCIFFDTYSNFIPITFMLGFYVSAVFTRWWQIFDNIGWIDTPCLWITQY--------------IKGETERAKCVRRNCIRYSILTQAMVYRDVAASVRKRFPTFNHLVTAGLMTEKEMAEFESIPSPHAKYWQPMHWLFSMITLARDEGMISSDIIYVDLMEKMRQFRVNILSLTLFDWVPVPLVYTQVVHLAVRSYFLIALFGRQYLHPESNRLNDF-KQTIDLYVPIMSLLQFIFFIGWMKVAEVLLNPLGEDDDDFECNWILDRNLQVGLMVVDTAYNRYPTLEKDQFWEDAIAEPLYTAESAMRPLNPQVGSCADMPTEEEPFMVRPRRRTLSRMSHWDG 393
BLAST of Bestrophin homolog vs. Ensembl Celegans
Match: best-22 (Bestrophin homolog 22 [Source:UniProtKB/Swiss-Prot;Acc:Q23369]) HSP 1 Score: 232.261 bits (591), Expect = 1.384e-69 Identity = 127/386 (32.90%), Postives = 217/386 (56.22%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVA-KSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFN----SKIYKLPLNEKSKFNKTRPFRGSFCEMRI 1214
MT+ Y DV F LL+RW+GS+++ ++ ++ A ++ IS I+R+ML + FE +I Y K A IP+ F++GF+V+ + +R+ N I WI +LL +T+ I+ E+TR+ +R ++RYLV S + L +S+ V++RF ++ L+ G++ E +++ + + + + W+ +++ + K ++ + L+ IV+EI KFR L L D + VPLVY QV+ LA+ YF+ CL+GRQFI+ + D +PI T++QF+VY+GW+K+A +L+NP+GEDD+D + N +ID N TG S VE + P +KD F+ + +Y + E+S P GS ++ +
Sbjct: 1 MTISYTLDVSQTNLQSFFSLLLRWRGSVWKAVFGQLAVWTAVFLLISCIYRYMLSPSQQDVFEQLIRYFDNKLDANIPLTFLLGFFVSFVVARWGSILNGIGWIDDASLLFATY--------------IRGADEETRVIRRNLVRYLVLSQALVLRDISMQVRKRFPTMDTLAASGLMTHEEMDILDHIKDPYSRYWTSIQWSLNLVYECQKKGKVDSYYLMNKIVDEIGKFRHGLASLLKYDWVPVPLVYPQVIFLAVRIYFMICLIGRQFIVTGPN-PSGIDLWLPITTMVQFLVYMGWMKVAEALLNPLGEDDDDLECNYIIDKNLITGYSMVEEHMAKTPAQKKDEFWGIDKIAPLYSMESAERS----VHPLVGSASKINL 367
BLAST of Bestrophin homolog vs. Ensembl Celegans
Match: best-22 (Bestrophin homolog 22 [Source:UniProtKB/Swiss-Prot;Acc:Q23369]) HSP 1 Score: 231.876 bits (590), Expect = 2.011e-69 Identity = 127/386 (32.90%), Postives = 217/386 (56.22%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVA-KSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFN----SKIYKLPLNEKSKFNKTRPFRGSFCEMRI 1214
MT+ Y DV F LL+RW+GS+++ ++ ++ A ++ IS I+R+ML + FE +I Y K A IP+ F++GF+V+ + +R+ N I WI +LL +T+ I+ E+TR+ +R ++RYLV S + L +S+ V++RF ++ L+ G++ E +++ + + + + W+ +++ + K ++ + L+ IV+EI KFR L L D + VPLVY QV+ LA+ YF+ CL+GRQFI+ + D +PI T++QF+VY+GW+K+A +L+NP+GEDD+D + N +ID N TG S VE + P +KD F+ + +Y + E+S P GS ++ +
Sbjct: 1 MTISYTLDVSQTNLQSFFSLLLRWRGSVWKAVFGQLAVWTAVFLLISCIYRYMLSPSQQDVFEQLIRYFDNKLDANIPLTFLLGFFVSFVVARWGSILNGIGWIDDASLLFATY--------------IRGADEETRVIRRNLVRYLVLSQALVLRDISMQVRKRFPTMDTLAASGLMTHEEMDILDHIKDPYSRYWTSIQWSLNLVYECQKKGKVDSYYLMNKIVDEIGKFRHGLASLLKYDWVPVPLVYPQVIFLAVRIYFMICLIGRQFIVTGPN-PSGIDLWLPITTMVQFLVYMGWMKVAEALLNPLGEDDDDLECNYIIDKNLITGYSMVEEHMAKTPAQKKDEFWGIDKIAPLYSMESAERS----VHPLVGSASKINL 367
BLAST of Bestrophin homolog vs. Ensembl Celegans
Match: best-22 (Bestrophin homolog 22 [Source:UniProtKB/Swiss-Prot;Acc:Q23369]) HSP 1 Score: 224.942 bits (572), Expect = 1.052e-66 Identity = 116/339 (34.22%), Postives = 199/339 (58.70%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVA-KSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENL 1085
MT+ Y DV F LL+RW+GS+++ ++ ++ A ++ IS I+R+ML + FE +I Y K A IP+ F++GF+V+ + +R+ N I WI +LL +T+ I+ E+TR+ +R ++RYLV S + L +S+ V++RF ++ L+ G++ E +++ + + + + W+ +++ + K ++ + L+ IV+EI KFR L L D + VPLVY QV+ LA+ YF+ CL+GRQFI+ + D +PI T++QF+VY+GW+K+A +L+NP+GEDD+D + N +ID N TG+S V+ +
Sbjct: 1 MTISYTLDVSQTNLQSFFSLLLRWRGSVWKAVFGQLAVWTAVFLLISCIYRYMLSPSQQDVFEQLIRYFDNKLDANIPLTFLLGFFVSFVVARWGSILNGIGWIDDASLLFATY--------------IRGADEETRVIRRNLVRYLVLSQALVLRDISMQVRKRFPTMDTLAASGLMTHEEMDILDHIKDPYSRYWTSIQWSLNLVYECQKKGKVDSYYLMNKIVDEIGKFRHGLASLLKYDWVPVPLVYPQVIFLAVRIYFMICLIGRQFIVTGPN-PSGIDLWLPITTMVQFLVYMGWMKVAEALLNPLGEDDDDLECNYIIDKNLITGLSIVDTM 324
BLAST of Bestrophin homolog vs. Ensembl Celegans
Match: best-22 (Bestrophin homolog 22 [Source:UniProtKB/Swiss-Prot;Acc:Q23369]) HSP 1 Score: 224.172 bits (570), Expect = 1.115e-66 Identity = 116/339 (34.22%), Postives = 199/339 (58.70%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVA-KSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENL 1085
MT+ Y DV F LL+RW+GS+++ ++ ++ A ++ IS I+R+ML + FE +I Y K A IP+ F++GF+V+ + +R+ N I WI +LL +T+ I+ E+TR+ +R ++RYLV S + L +S+ V++RF ++ L+ G++ E +++ + + + + W+ +++ + K ++ + L+ IV+EI KFR L L D + VPLVY QV+ LA+ YF+ CL+GRQFI+ + D +PI T++QF+VY+GW+K+A +L+NP+GEDD+D + N +ID N TG+S V+ +
Sbjct: 1 MTISYTLDVSQTNLQSFFSLLLRWRGSVWKAVFGQLAVWTAVFLLISCIYRYMLSPSQQDVFEQLIRYFDNKLDANIPLTFLLGFFVSFVVARWGSILNGIGWIDDASLLFATY--------------IRGADEETRVIRRNLVRYLVLSQALVLRDISMQVRKRFPTMDTLAASGLMTHEEMDILDHIKDPYSRYWTSIQWSLNLVYECQKKGKVDSYYLMNKIVDEIGKFRHGLASLLKYDWVPVPLVYPQVIFLAVRIYFMICLIGRQFIVTGPN-PSGIDLWLPITTMVQFLVYMGWMKVAEALLNPLGEDDDDLECNYIIDKNLITGLSIVDTM 324
BLAST of Bestrophin homolog vs. Ensembl Fly
Match: Best1 (gene:FBgn0040238 transcript:FBtr0082183) HSP 1 Score: 283.878 bits (725), Expect = 8.375e-87 Identity = 163/461 (35.36%), Postives = 263/461 (57.05%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIG-FLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIE---KCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQF----IIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKI-YKLPLN-EKSKFNKTRPFRGSFCEMRI-DNENWIASIKSLLIDKESPD-DGLLKSVSN--ISKQPSPRIRRQTPMFSPINYVANLISS--VKDESQP 1406
MT+ Y +V T G FLKLL+RW+GSI++L++ D L F Y AI+M++RF L K FE ++ Y + LIP++F++GFYV+++ +R+W + +IPW A+ VS+ + + E+ R+ +RTI+RY+ L + L+ VS VK+RF +N L G+L ++E +IE K P + +LP++WA SII +A + RI ++ + I++E+NKFR L D I VPLVYTQVVTLA+YSYFL+C +G+Q+ ++ + N+ D P+FT LQF Y+GW+K+A SL+NP GEDD+DF++N ++D N Q V+ + P KD +++ +LP +F + P S ++ + N +++ S+ ID+ + D G+ S N + SP + + S +N VA+ + +D+S+P
Sbjct: 1 MTITYTGEVATCRGFGCFLKLLLRWRGSIYKLVWLDLLAFLTIYYAINMVYRFGLNPAQKETFEAIVQYCDSYRELIPLSFVLGFYVSIVMTRWWNQYTSIPWPDPIAVFVSS--------------NVHGQDERGRMMRRTIMRYVCLCLTMVLANVSPRVKKRFPGLNNLVEAGLLNDNEKTIIETMNKAFPRPSKHWLPIVWAASIITRARKEGRIRDDFAVKTIIDELNKFRGQCGLLISYDTISVPLVYTQVVTLAVYSYFLTCCMGQQWTDGKVVGNTTYLNKVDLYFPVFTTLQFFFYMGWLKVAESLINPFGEDDDDFEVNWMVDRNLQVSYLIVDEMHHDHPELLKDQYWDEVFPNELPYTIAAERFRENHP-EPSTAKIEVPKNAAMPSTMSSVRIDEMADDASGIHFSAGNGKMRLDSSPSLVSVSGTLSRVNTVASALKRFLSRDDSRP 446
BLAST of Bestrophin homolog vs. Ensembl Fly
Match: Best1 (gene:FBgn0040238 transcript:FBtr0337020) HSP 1 Score: 283.878 bits (725), Expect = 1.182e-86 Identity = 163/461 (35.36%), Postives = 263/461 (57.05%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIG-FLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIE---KCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQF----IIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKI-YKLPLN-EKSKFNKTRPFRGSFCEMRI-DNENWIASIKSLLIDKESPD-DGLLKSVSN--ISKQPSPRIRRQTPMFSPINYVANLISSV--KDESQP 1406
MT+ Y +V T G FLKLL+RW+GSI++L++ D L F Y AI+M++RF L K FE ++ Y + LIP++F++GFYV+++ +R+W + +IPW A+ VS+ + + E+ R+ +RTI+RY+ L + L+ VS VK+RF +N L G+L ++E +IE K P + +LP++WA SII +A + RI ++ + I++E+NKFR L D I VPLVYTQVVTLA+YSYFL+C +G+Q+ ++ + N+ D P+FT LQF Y+GW+K+A SL+NP GEDD+DF++N ++D N Q V+ + P KD +++ +LP +F + P S ++ + N +++ S+ ID+ + D G+ S N + SP + + S +N VA+ + +D+S+P
Sbjct: 1 MTITYTGEVATCRGFGCFLKLLLRWRGSIYKLVWLDLLAFLTIYYAINMVYRFGLNPAQKETFEAIVQYCDSYRELIPLSFVLGFYVSIVMTRWWNQYTSIPWPDPIAVFVSS--------------NVHGQDERGRMMRRTIMRYVCLCLTMVLANVSPRVKKRFPGLNNLVEAGLLNDNEKTIIETMNKAFPRPSKHWLPIVWAASIITRARKEGRIRDDFAVKTIIDELNKFRGQCGLLISYDTISVPLVYTQVVTLAVYSYFLTCCMGQQWTDGKVVGNTTYLNKVDLYFPVFTTLQFFFYMGWLKVAESLINPFGEDDDDFEVNWMVDRNLQVSYLIVDEMHHDHPELLKDQYWDEVFPNELPYTIAAERFRENHP-EPSTAKIEVPKNAAMPSTMSSVRIDEMADDASGIHFSAGNGKMRLDSSPSLVSVSGTLSRVNTVASALKRFLSRDDSRP 446
BLAST of Bestrophin homolog vs. Ensembl Fly
Match: Best1 (gene:FBgn0040238 transcript:FBtr0114590) HSP 1 Score: 281.182 bits (718), Expect = 2.479e-85 Identity = 141/360 (39.17%), Postives = 219/360 (60.83%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIG-FLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIE---KCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQF----IIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFN 1127
MT+ Y +V T G FLKLL+RW+GSI++L++ D L F Y AI+M++RF L K FE ++ Y + LIP++F++GFYV+++ +R+W + +IPW A+ VS+ + + E+ R+ +RTI+RY+ L + L+ VS VK+RF +N L G+L ++E +IE K P + +LP++WA SII +A + RI ++ + I++E+NKFR L D I VPLVYTQVVTLA+YSYFL+C +G+Q+ ++ + N+ D P+FT LQF Y+GW+K+A SL+NP GEDD+DF++N ++D N Q V+ + P KD +++
Sbjct: 1 MTITYTGEVATCRGFGCFLKLLLRWRGSIYKLVWLDLLAFLTIYYAINMVYRFGLNPAQKETFEAIVQYCDSYRELIPLSFVLGFYVSIVMTRWWNQYTSIPWPDPIAVFVSS--------------NVHGQDERGRMMRRTIMRYVCLCLTMVLANVSPRVKKRFPGLNNLVEAGLLNDNEKTIIETMNKAFPRPSKHWLPIVWAASIITRARKEGRIRDDFAVKTIIDELNKFRGQCGLLISYDTISVPLVYTQVVTLAVYSYFLTCCMGQQWTDGKVVGNTTYLNKVDLYFPVFTTLQFFFYMGWLKVAESLINPFGEDDDDFEVNWMVDRNLQVSYLIVDEMHHDHPELLKDQYWD 346
BLAST of Bestrophin homolog vs. Ensembl Fly
Match: Best1 (gene:FBgn0040238 transcript:FBtr0306023) HSP 1 Score: 281.567 bits (719), Expect = 2.920e-85 Identity = 141/360 (39.17%), Postives = 219/360 (60.83%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIG-FLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIE---KCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQF----IIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFN 1127
MT+ Y +V T G FLKLL+RW+GSI++L++ D L F Y AI+M++RF L K FE ++ Y + LIP++F++GFYV+++ +R+W + +IPW A+ VS+ + + E+ R+ +RTI+RY+ L + L+ VS VK+RF +N L G+L ++E +IE K P + +LP++WA SII +A + RI ++ + I++E+NKFR L D I VPLVYTQVVTLA+YSYFL+C +G+Q+ ++ + N+ D P+FT LQF Y+GW+K+A SL+NP GEDD+DF++N ++D N Q V+ + P KD +++
Sbjct: 1 MTITYTGEVATCRGFGCFLKLLLRWRGSIYKLVWLDLLAFLTIYYAINMVYRFGLNPAQKETFEAIVQYCDSYRELIPLSFVLGFYVSIVMTRWWNQYTSIPWPDPIAVFVSS--------------NVHGQDERGRMMRRTIMRYVCLCLTMVLANVSPRVKKRFPGLNNLVEAGLLNDNEKTIIETMNKAFPRPSKHWLPIVWAASIITRARKEGRIRDDFAVKTIIDELNKFRGQCGLLISYDTISVPLVYTQVVTLAVYSYFLTCCMGQQWTDGKVVGNTTYLNKVDLYFPVFTTLQFFFYMGWLKVAESLINPFGEDDDDFEVNWMVDRNLQVSYLIVDEMHHDHPELLKDQYWD 346
BLAST of Bestrophin homolog vs. Ensembl Fly
Match: Best4 (gene:FBgn0036491 transcript:FBtr0113172) HSP 1 Score: 252.292 bits (643), Expect = 1.235e-76 Identity = 130/356 (36.52%), Postives = 213/356 (59.83%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIG-FLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCE---PYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFI-IVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFF 1124
MTV Y V T+ + FL LL+RW+GSI++LI+ D ++F Y +++ +R ++ E+ KR FE +++Y K+ +LIP++F++GF+V ++ +R+W + TIPW A+L+ST I ++ R+ +RTI+RY+ +I + +S VKRRF ++ G LLE+E +IE + P + ++P++WA SI+++A + +I ++ + I++E+N+ R L D I VPLVYTQVVT+A YS+FL ++G+Q+ SD R PI T+LQF Y+GW+K+A +L+NP GEDD+DF+LN +ID N V+ + P KD ++
Sbjct: 1 MTVTYTSRVSTSSVLSNFLGLLVRWRGSIYKLIWLDLIVFFGLYCLLAITYRLLVNEEGKRFFEAIMSYCEKNGSLIPLSFVLGFFVRIVMNRWWDQYTTIPWPDGIAILIST--------------SIHGSDDRARVMRRTILRYVCLCQVIVFTMISPRVKRRFPTYTQIIEAGFLLENEKKIIEAMDQAFPSYPKHWMPIVWAASIVMRARRENKIRDDYAVKTIIDELNQLRGNCGFLLYYDWISVPLVYTQVVTVATYSFFLFSVLGQQWNESHSDEDGTRIRRWFPILTVLQFFFYMGWLKVAETLINPFGEDDDDFELNWIIDRNLTVSYCIVDEMHQEHPELVKDQYW 342
BLAST of Bestrophin homolog vs. Ensembl Zebrafish
Match: best2 (bestrophin 2 [Source:ZFIN;Acc:ZDB-GENE-090312-127]) HSP 1 Score: 263.077 bits (671), Expect = 9.691e-82 Identity = 147/388 (37.89%), Postives = 218/388 (56.19%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVG--FYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVS-DYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRP-FRGSFCEMRIDNE 1223
MTV Y V A GF KLL+ WKGSI++++Y +FL F A Y AIS+ +RF L + KR FE + Y +LIP++F++G FYV L+ +R+W + +IP + ++S ++ E+ RL +RT++RY S L+ L VS V +RF I+ + G + E E + ++P +W T++ A + RI +++ ++EE+N FR LF D I VPLVYTQVVTLA+YS+FL CL+GRQF+ Y + D +PIFT+LQF Y GW+K+A L+NP GEDD+DF+ N LID NFQ + +V+ + P E+D ++N + P + F +P F+GS +M I E
Sbjct: 1 MTVTYTARVANARFCGFSKLLLAWKGSIYKVLYKEFLAFFAMYTAISITYRFFLVDGQKRYFEKLSIYCDNYASLIPMSFVLGMRFYVTLVVNRWWSQYTSIPLPDRVMCVLS--------------GGVQGSDERGRLLRRTLMRYSSLSALLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFESLHSPYNKYWIPCVWFTNLAAAARCEGRIKDDNTYKLLLEELNNFRGKCSMLFHYDMISVPLVYTQVVTLAVYSFFLVCLIGRQFLDPGQGYPGHDLDLYVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWLIDRNFQVSMMAVDEMYGDLPMMERDRYWNDSNPRPPYTAATLFVLRKPSFQGSTFDMTIPKE 374
BLAST of Bestrophin homolog vs. Ensembl Zebrafish
Match: best1 (bestrophin 1 [Source:ZFIN;Acc:ZDB-GENE-110411-214]) HSP 1 Score: 268.855 bits (686), Expect = 2.425e-81 Identity = 137/385 (35.58%), Postives = 220/385 (57.14%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRN-DFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNE 1223
MTV Y + V A F +LL+RWKGSI++L+Y + L+F Y IS+ +R +L E+ +R FE + Y + LIPV+F++GFYV L+ SR+W F ++PW + + LVS ++ E RL +R+++RY S ++ VS V +RF ++ L G++ E +++ + ++P MW S+ ++A + RI N+ + I+ E+N R L+ D I +PLVYTQVVT+A+YS+FL+CL+GRQF+ + N DF +P+FT+LQF Y+GW+K+A L+NP GEDD+DF+ N L+D N Q + SV+ + P E+D +++ + P S ++ F GS ++ + E
Sbjct: 1 MTVTYSRRVADARLGTFYRLLLRWKGSIYKLLYRELLIFTVMYCIISITYRCVLTEEQRRMFEKLSLYCDQYAQLIPVSFVLGFYVTLVVSRWWGQFESVPWPDRLSALVS--------------GHVRGADEGARLIRRSLMRYANLSGILIYRSVSTAVYKRFPTMSHLVQAGLMTAEELRQLQELPSPHNKFWVPCMWFVSLAMRARSEGRINNDVAMTAILNELNTLRSQCMRLYGYDWISLPLVYTQVVTVAVYSFFLTCLIGRQFLDPAQGYPGHNLDFYLPVFTLLQFFFYVGWLKVAEQLINPFGEDDDDFETNWLVDRNLQVSLLSVDEMYDLVPLVERDKYWDEAEPQPPYTAASAEHRKPSFMGSALDISVPKE 371
BLAST of Bestrophin homolog vs. Ensembl Zebrafish
Match: best4 (bestrophin 4 [Source:ZFIN;Acc:ZDB-GENE-070912-6]) HSP 1 Score: 228.794 bits (582), Expect = 1.530e-69 Identity = 121/354 (34.18%), Postives = 198/354 (55.93%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSK 1133
MTV Y V A GF KLL RWKGSI++L+Y +FL+F Y IS+++R +L + + F + + K LIP++F++GFYV F R+W + + P ++VS + E+ RL +RT++RY S ++ L +S V++RF + ++ G + E + + ++P+ W ++ +A + R+ ++ L +++E+N +R LF D I +PLVYTQVVT+A+YS+F L+GRQF+ + + D IPIFT+L+F Y GW+K+ ++NP GEDD+DF+ N LID N Q + +V+++ + PP EKD ++ K
Sbjct: 1 MTVSYTLKVANAKFGGFSKLLFRWKGSIYKLLYREFLVFCLLYTFISILYRCVLNNNQQEIFARLARHCNKFAKLIPMSFVLGFYVTQAFQRWWGQYTSFPLPDNLMMVVS--------------GNVHGTDERGRLLRRTLMRYANLSSVLILRSISTRVRKRFTTLEDIVEAGFMTTDELRKLNHLYSDFNKYWMPLAWFANLASQARKEGRVKDDIALRLLMDELNNYRSKCSMLFHYDWISIPLVYTQVVTVAVYSFFTFSLIGRQFVKPASS-EEHLDLYIPIFTLLEFFFYAGWLKVGELIINPFGEDDDDFETNQLIDRNIQVSMLAVDDMHQNLPPLEKDKYWVDK 339
BLAST of Bestrophin homolog vs. Ensembl Zebrafish
Match: best4 (bestrophin 4 [Source:ZFIN;Acc:ZDB-GENE-070912-6]) HSP 1 Score: 211.846 bits (538), Expect = 1.711e-63 Identity = 114/329 (34.65%), Postives = 183/329 (55.62%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQ 1058
MTV Y V A GF KLL RWKGSI++L+Y +FL+F Y IS+++R +L + + F + + K LIP++F++GFYV F R+W + + P ++VS + E+ RL +RT++RY S ++ L +S V++RF + ++ G + E + + ++P+ W ++ +A + R+ ++ L +++E+N +R LF D I +PLVYTQVVT+A+YS+F L+GRQF+ + + D IPIFT+L+F Y GW+K+ ++NP GEDD+DF+ N LID N Q
Sbjct: 1 MTVSYTLKVANAKFGGFSKLLFRWKGSIYKLLYREFLVFCLLYTFISILYRCVLNNNQQEIFARLARHCNKFAKLIPMSFVLGFYVTQAFQRWWGQYTSFPLPDNLMMVVS--------------GNVHGTDERGRLLRRTLMRYANLSSVLILRSISTRVRKRFTTLEDIVEAGFMTTDELRKLNHLYSDFNKYWMPLAWFANLASQARKEGRVKDDIALRLLMDELNNYRSKCSMLFHYDWISIPLVYTQVVTVAVYSFFTFSLIGRQFVKPASS-EEHLDLYIPIFTLLEFFFYAGWLKVGELIINPFGEDDDDFETNQLIDRNIQ 314
BLAST of Bestrophin homolog vs. Ensembl Zebrafish
Match: best1 (bestrophin 1 [Source:ZFIN;Acc:ZDB-GENE-110411-214]) HSP 1 Score: 157.147 bits (396), Expect = 5.781e-43 Identity = 84/235 (35.74%), Postives = 132/235 (56.17%), Query Frame = 3
Query: 657 FLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRN-DFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNENW-----IASIKSLLIDKESPDDGLLKSVSNISKQPSPRIRRQTP 1343
++P MW S+ ++A + RI N+ + I+ E+N R L+ D I +PLVYTQVVT+A+YS+FL+CL+GRQF+ + N DF +P+FT+LQF Y+GW+K+A L+NP GEDD+DF+ N L+D N Q + SV+ + P E+D +++ + P S ++ F GS ++ + E + IK ++ + L S+S + SP R TP
Sbjct: 22 WVPCMWFVSLAMRARSEGRINNDVAMTAILNELNTLRSQCMRLYGYDWISLPLVYTQVVTVAVYSFFLTCLIGRQFLDPAQGYPGHNLDFYLPVFTLLQFFFYVGWLKVAEQLINPFGEDDDDFETNWLVDRNLQVSLLSVDEMYDLVPLVERDKYWDEAEPQPPYTAASAEHRKPSFMGSALDISVPKEEMEFQHNLEQIKEH--EEANHSTPFLGSLSRLLGVQSPNFPRSTP 254
BLAST of Bestrophin homolog vs. Ensembl Xenopus
Match: best1 (bestrophin 1 [Source:NCBI gene;Acc:100302038]) HSP 1 Score: 259.61 bits (662), Expect = 7.102e-81 Identity = 138/386 (35.75%), Postives = 217/386 (56.22%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHE----SGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFII-VSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRI 1214
MTV Y V A F +LL+RW+GSI++L+Y +FL+F + Y IS+ +RF+L E + FE + Y LIPV+F++GFYV L+ SR+W + ++PW + LVS+ + E+ R+ +RT++RY + L+ L VS V RF + + N G + E GL+ + ++P +W ++ + A + RI + +L I++E+N R L+ D I VPLVYTQVVT+A+YS+FL+CL+GRQF+ Y + D +P+FT+LQF Y GW+K+A L+NP G+DD+DF+ N LID N Q + +V+ + PP EKD ++N + P + + ++GS ++RI
Sbjct: 1 MTVTYSNRVADARLGTFSRLLLRWRGSIYKLLYREFLIFISCYFIISVTYRFLLNEQQRIYFEKLALYCDNYAELIPVSFVLGFYVTLVVSRWWGQYESVPWPDRLMCLVSS--------------NVHGTDERGRMLRRTLMRYANLTGLLILRSVSTAVYMRFPTLQHVVNAGFMTPTERSKFDGLVSSHNKF----WVPCVWFANLAVTARSEGRIRDNVVLQLILKELNSLRTQCGRLYGYDWISVPLVYTQVVTVAVYSFFLACLIGRQFLDPQKGYPGHDMDLYVPVFTLLQFFFYAGWLKVAEQLINPFGQDDDDFETNWLIDRNLQVSLLAVDEMHQDVPPLEKDIYWNDSDPQPPYTASTVETRRPSYQGSAFDIRI 368
BLAST of Bestrophin homolog vs. Ensembl Xenopus
Match: best1 (bestrophin 1 [Source:NCBI gene;Acc:100302038]) HSP 1 Score: 257.684 bits (657), Expect = 4.280e-80 Identity = 136/380 (35.79%), Postives = 213/380 (56.05%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHE----SGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFII-VSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGS 1196
MTV Y V A F +LL+RW+GSI++L+Y +FL+F + Y IS+ +RF+L E + FE + Y LIPV+F++GFYV L+ SR+W + ++PW + LVS+ + E+ R+ +RT++RY + L+ L VS V RF + + N G + E GL+ + ++P +W ++ + A + RI + +L I++E+N R L+ D I VPLVYTQVVT+A+YS+FL+CL+GRQF+ Y + D +P+FT+LQF Y GW+K+A L+NP G+DD+DF+ N LID N Q + +V+ + PP EKD ++N + P + + ++GS
Sbjct: 1 MTVTYSNRVADARLGTFSRLLLRWRGSIYKLLYREFLIFISCYFIISVTYRFLLNEQQRIYFEKLALYCDNYAELIPVSFVLGFYVTLVVSRWWGQYESVPWPDRLMCLVSS--------------NVHGTDERGRMLRRTLMRYANLTGLLILRSVSTAVYMRFPTLQHVVNAGFMTPTERSKFDGLVSSHNKF----WVPCVWFANLAVTARSEGRIRDNVVLQLILKELNSLRTQCGRLYGYDWISVPLVYTQVVTVAVYSFFLACLIGRQFLDPQKGYPGHDMDLYVPVFTLLQFFFYAGWLKVAEQLINPFGQDDDDFETNWLIDRNLQVSLLAVDEMHQDVPPLEKDIYWNDSDPQPPYTASTVETRRPSYQGS 362
BLAST of Bestrophin homolog vs. Ensembl Xenopus
Match: best1 (bestrophin 1 [Source:NCBI gene;Acc:100302038]) HSP 1 Score: 257.684 bits (657), Expect = 8.337e-80 Identity = 136/380 (35.79%), Postives = 213/380 (56.05%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHE----SGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFII-VSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGS 1196
MTV Y V A F +LL+RW+GSI++L+Y +FL+F + Y IS+ +RF+L E + FE + Y LIPV+F++GFYV L+ SR+W + ++PW + LVS+ + E+ R+ +RT++RY + L+ L VS V RF + + N G + E GL+ + ++P +W ++ + A + RI + +L I++E+N R L+ D I VPLVYTQVVT+A+YS+FL+CL+GRQF+ Y + D +P+FT+LQF Y GW+K+A L+NP G+DD+DF+ N LID N Q + +V+ + PP EKD ++N + P + + ++GS
Sbjct: 1 MTVTYSNRVADARLGTFSRLLLRWRGSIYKLLYREFLIFISCYFIISVTYRFLLNEQQRIYFEKLALYCDNYAELIPVSFVLGFYVTLVVSRWWGQYESVPWPDRLMCLVSS--------------NVHGTDERGRMLRRTLMRYANLTGLLILRSVSTAVYMRFPTLQHVVNAGFMTPTERSKFDGLVSSHNKF----WVPCVWFANLAVTARSEGRIRDNVVLQLILKELNSLRTQCGRLYGYDWISVPLVYTQVVTVAVYSFFLACLIGRQFLDPQKGYPGHDMDLYVPVFTLLQFFFYAGWLKVAEQLINPFGQDDDDFETNWLIDRNLQVSLLAVDEMHQDVPPLEKDIYWNDSDPQPPYTASTVETRRPSYQGS 362
BLAST of Bestrophin homolog vs. Ensembl Xenopus
Match: ifitm3 (interferon induced transmembrane protein 3 [Source:Xenbase;Acc:XB-GENE-5852510]) HSP 1 Score: 263.462 bits (672), Expect = 2.558e-79 Identity = 141/406 (34.73%), Postives = 222/406 (54.68%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSD-YLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDN-----ENWIASIKSLLIDKESP 1271
MTV Y V A GF +LL++W+GSI++L+Y +FLLF + Y +S+I+RF L + KR FE V Y K IPV F++GFYV L+ +R+W F +PW + L+S+ + E RL +RT++RY+ + L+ VS V +RF ++ + G + E L + + ++ ++PV+W ++ KA + RI + L ++ E+NKFR LF D + +PLVYTQVVTLA+Y++F +C++GRQF+ Y + D IP+FT+LQF Y GW+K+A L+NP GEDD+DF+ N ID N Q + +V+ + + P +D ++N + P + F GS M + + E+W L+D++ P
Sbjct: 1 MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFLLFTSLYTTLSVIYRFFLTDSQKRYFEKVSMYCDKYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISS--------------NVHGRDEYGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTSDERKLFDSLKSPHLKYWVPVIWFGNLASKARSEGRIRDSIDLQMMMNEMNKFRSWCSLLFGYDWVGIPLVYTQVVTLAVYTFFFACIIGRQFLDPKQAYPGHDLDLYIPVFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWCIDRNLQVSLMAVDEMHMNLPKMNRDIYWNDSDVRPPYTLAAADYCIPSFLGSTVHMGLPDSVFLREDW-------LLDEDKP 385
BLAST of Bestrophin homolog vs. Ensembl Xenopus
Match: best1 (bestrophin 1 [Source:NCBI gene;Acc:100302038]) HSP 1 Score: 256.914 bits (655), Expect = 4.769e-79 Identity = 136/380 (35.79%), Postives = 213/380 (56.05%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHE----SGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFII-VSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGS 1196
MTV Y V A F +LL+RW+GSI++L+Y +FL+F + Y IS+ +RF+L E + FE + Y LIPV+F++GFYV L+ SR+W + ++PW + LVS+ + E+ R+ +RT++RY + L+ L VS V RF + + N G + E GL+ + ++P +W ++ + A + RI + +L I++E+N R L+ D I VPLVYTQVVT+A+YS+FL+CL+GRQF+ Y + D +P+FT+LQF Y GW+K+A L+NP G+DD+DF+ N LID N Q + +V+ + PP EKD ++N + P + + ++GS
Sbjct: 1 MTVTYSNRVADARLGTFSRLLLRWRGSIYKLLYREFLIFISCYFIISVTYRFLLNEQQRIYFEKLALYCDNYAELIPVSFVLGFYVTLVVSRWWGQYESVPWPDRLMCLVSS--------------NVHGTDERGRMLRRTLMRYANLTGLLILRSVSTAVYMRFPTLQHVVNAGFMTPTERSKFDGLVSSHNKF----WVPCVWFANLAVTARSEGRIRDNVVLQLILKELNSLRTQCGRLYGYDWISVPLVYTQVVTVAVYSFFLACLIGRQFLDPQKGYPGHDMDLYVPVFTLLQFFFYAGWLKVAEQLINPFGQDDDDFETNWLIDRNLQVSLLAVDEMHQDVPPLEKDIYWNDSDPQPPYTASTVETRRPSYQGS 362
BLAST of Bestrophin homolog vs. Ensembl Mouse
Match: Best2 (bestrophin 2 [Source:MGI Symbol;Acc:MGI:2387588]) HSP 1 Score: 266.929 bits (681), Expect = 2.517e-82 Identity = 140/387 (36.18%), Postives = 220/387 (56.85%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRN-DFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRP-FRGSFCEMRIDNEN 1226
MTV Y V A GF +LL+ W+GSI++L++ + L F YMA+S +RF+L E+ KR FE ++ Y + +LIPV+F++GFYV L+ R+W + +P +V+ + ++ RL +RT++RY S ++ L VS V +RF I+ + G + E E + ++P +W +S+ +A + RI + S L ++EE+N FR LF D I +PLVYTQVVT+A+YSYFL+CL+GRQF+ + K+ D +PIFT+LQF Y GW+K+A L+NP GEDD+DF+ N LID NFQ + +V+ + EKD ++++ + P + F +P F+GS ++ + E+
Sbjct: 1 MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGLYMALSAAYRFLLAEEQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVHRWWNQYLCMPLPDALMCIVA--------------GTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSSLAAQARREGRIRDNSALKLLLEELNVFRSKCGMLFHYDWISIPLVYTQVVTIAVYSYFLACLIGRQFLDPAQGYKDHTLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAMLEKDLYWDAAEARAPYTAATAFLLQQPSFQGSTFDIALAKED 373
BLAST of Bestrophin homolog vs. Ensembl Mouse
Match: Best2 (bestrophin 2 [Source:MGI Symbol;Acc:MGI:2387588]) HSP 1 Score: 266.929 bits (681), Expect = 2.517e-82 Identity = 140/387 (36.18%), Postives = 220/387 (56.85%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRN-DFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRP-FRGSFCEMRIDNEN 1226
MTV Y V A GF +LL+ W+GSI++L++ + L F YMA+S +RF+L E+ KR FE ++ Y + +LIPV+F++GFYV L+ R+W + +P +V+ + ++ RL +RT++RY S ++ L VS V +RF I+ + G + E E + ++P +W +S+ +A + RI + S L ++EE+N FR LF D I +PLVYTQVVT+A+YSYFL+CL+GRQF+ + K+ D +PIFT+LQF Y GW+K+A L+NP GEDD+DF+ N LID NFQ + +V+ + EKD ++++ + P + F +P F+GS ++ + E+
Sbjct: 1 MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGLYMALSAAYRFLLAEEQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVHRWWNQYLCMPLPDALMCIVA--------------GTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSSLAAQARREGRIRDNSALKLLLEELNVFRSKCGMLFHYDWISIPLVYTQVVTIAVYSYFLACLIGRQFLDPAQGYKDHTLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAMLEKDLYWDAAEARAPYTAATAFLLQQPSFQGSTFDIALAKED 373
BLAST of Bestrophin homolog vs. Ensembl Mouse
Match: Best2 (bestrophin 2 [Source:MGI Symbol;Acc:MGI:2387588]) HSP 1 Score: 266.929 bits (681), Expect = 2.517e-82 Identity = 140/387 (36.18%), Postives = 220/387 (56.85%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRN-DFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRP-FRGSFCEMRIDNEN 1226
MTV Y V A GF +LL+ W+GSI++L++ + L F YMA+S +RF+L E+ KR FE ++ Y + +LIPV+F++GFYV L+ R+W + +P +V+ + ++ RL +RT++RY S ++ L VS V +RF I+ + G + E E + ++P +W +S+ +A + RI + S L ++EE+N FR LF D I +PLVYTQVVT+A+YSYFL+CL+GRQF+ + K+ D +PIFT+LQF Y GW+K+A L+NP GEDD+DF+ N LID NFQ + +V+ + EKD ++++ + P + F +P F+GS ++ + E+
Sbjct: 1 MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGLYMALSAAYRFLLAEEQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVHRWWNQYLCMPLPDALMCIVA--------------GTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSSLAAQARREGRIRDNSALKLLLEELNVFRSKCGMLFHYDWISIPLVYTQVVTIAVYSYFLACLIGRQFLDPAQGYKDHTLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAMLEKDLYWDAAEARAPYTAATAFLLQQPSFQGSTFDIALAKED 373
BLAST of Bestrophin homolog vs. Ensembl Mouse
Match: Best1 (bestrophin 1 [Source:MGI Symbol;Acc:MGI:1346332]) HSP 1 Score: 261.536 bits (667), Expect = 2.485e-81 Identity = 135/386 (34.97%), Postives = 220/386 (56.99%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVS-DYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNEN 1226
MT+ Y V A F LL+ W+GSI++L+Y +FL+F Y +I ++R +L D + FE + Y LIP++F++GFYV L+ SR+W + +PW + + VS+F ++ + E+ RL +RT+IRY + ++ L +S V +RF ++ L G + E ++K ++P +W ++ +KA RI + LL ++ E+ R +L+ D I +PLVYTQVVT+A+YS+FL+CL+GRQF+ + DY + D V+P+FTILQF+ Y+GW+K+A L+NP GEDD+DF+ N +ID N Q + SV+ + + PP E+D ++N + P S ++ F GS + + E+
Sbjct: 1 MTITYTNKVANARLGSFSSLLLCWRGSIYKLLYGEFLVFIFLYYSIRGLYRMVLSSDQQLLFEKLALYCDSYIQLIPISFVLGFYVTLVVSRWWSQYENLPWPDRLMIQVSSF--------------VEGKDEEGRLLRRTLIRYAILGQVLILRSISTSVYKRFPTLHHLVLAGFMTHGEHKQLQKLGLPHNTFWVPWVWFANLSMKAYLGGRIRDTVLLQSLMNEVCTLRTQCGQLYAYDWISIPLVYTQVVTVAVYSFFLACLIGRQFLNPNKDYPGHEMDLVVPVFTILQFLFYMGWLKVAEQLINPFGEDDDDFETNWIIDRNLQVSLLSVDGMHQNLPPMERDMYWNEAAPQPPYTAASARSRRHSFMGSTFNISLKKED 372
BLAST of Bestrophin homolog vs. Ensembl Mouse
Match: Best3 (bestrophin 3 [Source:MGI Symbol;Acc:MGI:3580298]) HSP 1 Score: 267.7 bits (683), Expect = 5.494e-81 Identity = 142/426 (33.33%), Postives = 231/426 (54.23%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFI-IVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNENWIASIKSLLIDKESPDDGLLKSV----SNISKQPSPRIRR 1334
MTV Y V A GF +LL++W+GSI++L+Y +F++FA Y AIS+++R +L KR FE + Y + IPV F++GFYV L+ +R+W F +PW + LL+S+ + + RL +RT++RY+ + L+ VS V +RF ++ + G + E L + + ++ ++P +W ++ KA ++ RI + L ++ E+N++R LF D + +PLVYTQVVTLA+Y++F +CL+GRQF+ Y+ + D +PIFT+LQF Y GW+K+A L+NP GEDD+DF+ N ID N Q + +V+ + S P +KD +++ + P + F GS +M + N+ A +K +++ V S SPR RR
Sbjct: 1 MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGAQKRYFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMLLISS--------------SVHGSDQHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTADERKLFDHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVVTLAVYTFFFACLIGRQFLDPTKGYVGHDLDLYVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFLGSTIQMGLSGSNFPAEDWLWNYEKHGNRHSVMRRVKRFLSTHEHPGSPRRRR 412
BLAST of Bestrophin homolog vs. UniProt/SwissProt
Match: sp|Q8BGM5|BEST2_MOUSE (Bestrophin-2 OS=Mus musculus OX=10090 GN=Best2 PE=2 SV=1) HSP 1 Score: 266.929 bits (681), Expect = 1.818e-81 Identity = 140/387 (36.18%), Postives = 220/387 (56.85%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRN-DFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRP-FRGSFCEMRIDNEN 1226
MTV Y V A GF +LL+ W+GSI++L++ + L F YMA+S +RF+L E+ KR FE ++ Y + +LIPV+F++GFYV L+ R+W + +P +V+ + ++ RL +RT++RY S ++ L VS V +RF I+ + G + E E + ++P +W +S+ +A + RI + S L ++EE+N FR LF D I +PLVYTQVVT+A+YSYFL+CL+GRQF+ + K+ D +PIFT+LQF Y GW+K+A L+NP GEDD+DF+ N LID NFQ + +V+ + EKD ++++ + P + F +P F+GS ++ + E+
Sbjct: 1 MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGLYMALSAAYRFLLAEEQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVHRWWNQYLCMPLPDALMCIVA--------------GTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSSLAAQARREGRIRDNSALKLLLEELNVFRSKCGMLFHYDWISIPLVYTQVVTIAVYSYFLACLIGRQFLDPAQGYKDHTLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAMLEKDLYWDAAEARAPYTAATAFLLQQPSFQGSTFDIALAKED 373
BLAST of Bestrophin homolog vs. UniProt/SwissProt
Match: sp|Q8NFU1|BEST2_HUMAN (Bestrophin-2 OS=Homo sapiens OX=9606 GN=BEST2 PE=1 SV=1) HSP 1 Score: 266.929 bits (681), Expect = 2.075e-81 Identity = 141/387 (36.43%), Postives = 222/387 (57.36%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRN-DFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRP-FRGSFCEMRIDNEN 1226
MTV Y V A GF +LL+ W+GSI++L++ + L F FYMA+S +RF+L E KR FE ++ Y + +LIPV+F++GFYV L+ +R+W + +P +V+ + ++ RL +RT++RY S ++ L VS V +RF I+ + G + E E + ++P +W +++ +A + RI + S L ++EE+N FR LF D I VPLVYTQVVT+A+YSYFL+CL+GRQF+ + K+ + D +PIFT+LQF Y GW+K+A L+NP GEDD+DF+ N LID NFQ + +V+ + EKD ++++ + P + F +P F+GS ++ + E+
Sbjct: 1 MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYRFVLTEGQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVA--------------GTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYTQVVTIALYSYFLACLIGRQFLDPAQGYKDHDLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAVLEKDLYWDAAEARAPYTAATVFQLRQPSFQGSTFDITLAKED 373
BLAST of Bestrophin homolog vs. UniProt/SwissProt
Match: sp|Q6H1V1|BEST3_MOUSE (Bestrophin-3 OS=Mus musculus OX=10090 GN=Best3 PE=2 SV=1) HSP 1 Score: 267.7 bits (683), Expect = 3.843e-80 Identity = 142/426 (33.33%), Postives = 231/426 (54.23%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFI-IVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNENWIASIKSLLIDKESPDDGLLKSV----SNISKQPSPRIRR 1334
MTV Y V A GF +LL++W+GSI++L+Y +F++FA Y AIS+++R +L KR FE + Y + IPV F++GFYV L+ +R+W F +PW + LL+S+ + + RL +RT++RY+ + L+ VS V +RF ++ + G + E L + + ++ ++P +W ++ KA ++ RI + L ++ E+N++R LF D + +PLVYTQVVTLA+Y++F +CL+GRQF+ Y+ + D +PIFT+LQF Y GW+K+A L+NP GEDD+DF+ N ID N Q + +V+ + S P +KD +++ + P + F GS +M + N+ A +K +++ V S SPR RR
Sbjct: 1 MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGAQKRYFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMLLISS--------------SVHGSDQHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTADERKLFDHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVVTLAVYTFFFACLIGRQFLDPTKGYVGHDLDLYVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFLGSTIQMGLSGSNFPAEDWLWNYEKHGNRHSVMRRVKRFLSTHEHPGSPRRRR 412
BLAST of Bestrophin homolog vs. UniProt/SwissProt
Match: sp|O88870|BEST1_MOUSE (Bestrophin-1 OS=Mus musculus OX=10090 GN=Best1 PE=2 SV=3) HSP 1 Score: 263.077 bits (671), Expect = 1.787e-79 Identity = 135/386 (34.97%), Postives = 220/386 (56.99%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVS-DYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNEN 1226
MT+ Y V A F LL+ W+GSI++L+Y +FL+F Y +I ++R +L D + FE + Y LIP++F++GFYV L+ SR+W + +PW + + VS+F ++ + E+ RL +RT+IRY + ++ L +S V +RF ++ L G + E ++K ++P +W ++ +KA RI + LL ++ E+ R +L+ D I +PLVYTQVVT+A+YS+FL+CL+GRQF+ + DY + D V+P+FTILQF+ Y+GW+K+A L+NP GEDD+DF+ N +ID N Q + SV+ + + PP E+D ++N + P S ++ F GS + + E+
Sbjct: 1 MTITYTNKVANARLGSFSSLLLCWRGSIYKLLYGEFLVFIFLYYSIRGLYRMVLSSDQQLLFEKLALYCDSYIQLIPISFVLGFYVTLVVSRWWSQYENLPWPDRLMIQVSSF--------------VEGKDEEGRLLRRTLIRYAILGQVLILRSISTSVYKRFPTLHHLVLAGFMTHGEHKQLQKLGLPHNTFWVPWVWFANLSMKAYLGGRIRDTVLLQSLMNEVCTLRTQCGQLYAYDWISIPLVYTQVVTVAVYSFFLACLIGRQFLNPNKDYPGHEMDLVVPVFTILQFLFYMGWLKVAEQLINPFGEDDDDFETNWIIDRNLQVSLLSVDGMHQNLPPMERDMYWNEAAPQPPYTAASARSRRHSFMGSTFNISLKKED 372
BLAST of Bestrophin homolog vs. UniProt/SwissProt
Match: sp|Q8N1M1|BEST3_HUMAN (Bestrophin-3 OS=Homo sapiens OX=9606 GN=BEST3 PE=1 SV=1) HSP 1 Score: 262.307 bits (669), Expect = 4.430e-78 Identity = 135/393 (34.35%), Postives = 217/393 (55.22%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFI-IVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRID-----NENWI 1232
MTV Y V A GF +LL++W+GSI++L+Y +F++FA Y AIS+++R +L KR FE + Y + IPV F++GFYV L+ +R+W F +PW + L+S+ + E RL +RT++RY+ + L+ VS V +RF ++ + G + E L + ++ ++P +W ++ KA ++ RI + L ++ E+N++R LF D + +PLVYTQVVTLA+Y++F +CL+GRQF+ Y + D IPIFT+LQF Y GW+K+A L+NP GEDD+DF+ N ID N Q + +V+ + S P +KD +++ + P + F GS +M + +E W+
Sbjct: 1 MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKRYFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISS--------------SVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVVTLAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFLGSTVQMGLSGSDFPDEEWL 379
BLAST of Bestrophin homolog vs. TrEMBL
Match: A0A4S2KY96 (Bestrophin homolog OS=Opisthorchis felineus OX=147828 GN=CRM22_010477 PE=3 SV=1) HSP 1 Score: 359.762 bits (922), Expect = 9.896e-115 Identity = 193/487 (39.63%), Postives = 299/487 (61.40%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRN--DFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNE-NWIASIKSLLIDKESPDDGLLKSVSNISKQPSPR-------IRRQTPMFSPINYVANLISSVKDESQPEITSSEEVSEPRKKSSEKYSLLAIVEEDSASS 1502
MTV+Y Q VLT GP FL+LL++W+G +F+LIY D L+F Y +IS+I+RF L E +R FE++I ++ + QA+IPVAFI+GFYV LIF+RFW F IPW+ K A+ ++ + E+ RL +RT +RYL+ SL++T +RV++ KRRF N++ G+ E E+ L++ E + QPF P++W TS+I A +K I NE L+ ++ E+N RQ L +F +D +CVPLVYTQVVTL++YSYF++ L+GRQ+I+ S ++++N DF P FT L+ I+Y+GW+K+A +LVNPMGEDDED D+N +ID+N++ V+ +K S P +D +N + +LP E+S+ RP RGS ++ + + ++I S+ S+ G+ + ++ PS + +RR T + YV + +S + + Q +T E +S P K+S E + +ED SS
Sbjct: 1 MTVQYSQLVLTGGPGVFLRLLLKWRGCVFKLIYVDILVFLGLYFSISLIYRFALTEPLQRNFESLILFINRFQAMIPVAFILGFYVALIFARFWHQFMVIPWVLKIAVGLTA--------------HLPGSDERPRLLRRTCMRYLMGSLILTCTRVNLVAKRRFPNLDAFVTAGVFTEEETKLLDGMELH-FQPFAPIIWTTSLITLAEKEKIITNEHALVFLIAEVNNLRQGLLNVFFMDYVCVPLVYTQVVTLSVYSYFIASLIGRQYIMSSSTMRDQNNHDFYFPFFTTLELIIYVGWLKVAETLVNPMGEDDEDIDINEVIDFNWKAAWCIVDGVKPSPPAVVRDAHWNQTVVELPHTEESRQLPCRPCRGSVFDLNLQSSTDFIGSLISM--------TGVRSAQDTSTRFPSAKRSSVLSILRRPTLLHVREPYVMDSPASDEPDLQISLTVPERLS-PSKQSVELH------DEDHKSS 457
BLAST of Bestrophin homolog vs. TrEMBL
Match: A0A068Y3U9 (Bestrophin homolog OS=Echinococcus multilocularis OX=6211 PE=3 SV=1) HSP 1 Score: 350.903 bits (899), Expect = 8.693e-112 Identity = 177/414 (42.75%), Postives = 260/414 (62.80%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFII-VSDYLKN-RNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNENWIASIKSLLIDKESPDDGLLKSVSNIS 1307
MTV+Y QDVLT GP+ FL+LL+RWKG + +LIY DF++F Y +S I+RF L ++QFE+V+ YV Q +IP++FI+GFYV L+FSRFWQ FN++PW+ F P ++ + + + R +RT +RY+ +SL+I SR+ + K+RF L GIL + E LI+ +P QPFLP++WAT+I ++A I N L+ +++ IN FR+ L LFL+D++CVPLVYTQVVTLA+YSYFLS ++GRQFI+ SDY + R D+ +P++TIL+FIVY+GW+K+A +LVNPMGEDDEDFD+N +ID N+ G+ V+ K +D F++S LP SK ++ + I S+ ++ + P D L +VS ++
Sbjct: 1 MTVQYNQDVLTGGPVVFLRLLLRWKGCVIKLIYIDFIVFILAYAVVSCIYRFALTASQQKQFESVVLYVFDFQQMIPISFILGFYVQLVFSRFWQQFNSVPWV---------------FTPTLAVIGAIQGEGRARAIRRTCVRYMNASLIIASSRLHVAAKKRFPTTQHLVQAGILTQREGDLIDSTDPVAAQPFLPLVWATAISMRAEKDGYIRNPHALVNLIQVINGFRESLLRLFLMDKVCVPLVYTQVVTLAVYSYFLSSIIGRQFIVNTSDYSEPFRKDYYVPLYTILEFIVYMGWLKVAETLVNPMGEDDEDFDINAIIDCNWSYGMHMVDR-KYHPTELVRDKFWDSTNVSLPHTADSK--------------KLQSTQMIGSVFNIDVLGTDPHDRNLNTVSAVN 384
BLAST of Bestrophin homolog vs. TrEMBL
Match: A0A068WMI5 (Bestrophin homolog OS=Echinococcus granulosus OX=6210 GN=EgrG_000672700 PE=3 SV=1) HSP 1 Score: 349.362 bits (895), Expect = 3.169e-111 Identity = 172/377 (45.62%), Postives = 246/377 (65.25%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFII-VSDYLKN-RNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGS 1196
MTV+Y QDVLT GP+ FL+LL+RWKG + +LIY DF++F Y +S I+RF L ++QFE+V+ YV Q +IP++FI+GFYV L+FSRFWQ FN++PW+ F P ++ + + + R +RT +RY+ +SL+I SR+ + K+RF L GIL + E LI+ P QPFLP++WAT+I ++A I N L+ +++ IN FR+ L LFL+D++CVPLVYTQVVTLA+YSYFLS ++GRQFI+ SDY + R D+ +P++TIL+FIVY+GW+K+A +LVNPMGEDDEDFD+N +ID N+ G+ V+ K +D F++S LP SK ++ GS
Sbjct: 1 MTVQYNQDVLTGGPVVFLRLLLRWKGCVIKLIYIDFIVFILAYAVVSCIYRFALTASQQKQFESVVLYVFDFQQMIPISFILGFYVQLVFSRFWQQFNSVPWV---------------FTPTLAVIGAIQGEGRARAIRRTCVRYMNASLIIASSRLHVAAKKRFPTTQHLVQAGILTQREGDLIDSTNPVAAQPFLPLVWATAISMRAEKDGYIRNSHALVNLIQVINGFRESLLRLFLMDKVCVPLVYTQVVTLAVYSYFLSSIIGRQFIVNTSDYSEPFRKDYYVPLYTILEFIVYMGWLKVAETLVNPMGEDDEDFDINAIIDCNWSYGMHMVDR-KYHPTELVRDKFWDSTNVSLPHTADSKKLQSTQMIGS 361
BLAST of Bestrophin homolog vs. TrEMBL
Match: A0A4E0RSY8 (Bestrophin homolog OS=Fasciola hepatica OX=6192 GN=D915_009373 PE=3 SV=1) HSP 1 Score: 350.132 bits (897), Expect = 1.164e-110 Identity = 185/465 (39.78%), Postives = 281/465 (60.43%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYL---KNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDN-ENWIASIKSLLIDKESPDDGLLKSVSNISKQPSPRIRRQTPMFSPINYVANLISSVKDESQPEITSSEEVSEPRKKSS 1454
MTV+Y Q VLT GP F +LL++W+G +F+LIY D L+F Y IS I+RF L + +R FE +I + QA+IPVAFI+GFY+NLIF+RFW F IPW+ K A+ + T + ++TRL +RT +RY++ SL++T +R+S+ KRRF + + G+ + E +I +P++ Q F+P++WATS+I A ++R+ N+ L+ +++E+N FRQ L +LF +D +CVPLVYTQVVTL++YSYF++ L+GRQ+I+ S N D P FT+L+FI+Y+GW+K+A +LVNPMGEDDEDFD+N +ID+N++T V+ +K S P +D ++ + +LP E+S+ +RP RGS ++ + + ++ S SL + S D R RR + S +N ISS DE + EE K +S
Sbjct: 1 MTVQYNQLVLTGGPGVFFRLLLKWRGCVFKLIYFDILVFGTLYAIISCIYRFALSSEMQRTFERLILFTNNFQAMIPVAFILGFYINLIFNRFWYQFGIIPWVLKFAIALVT--------------NVSGFDDRTRLIRRTCVRYVLGSLILTTARISVAAKRRFPTMESFVSGGVFTDEEIKMIMAQQPHV-QSFVPIVWATSLITLAEKERRLTNQHALVLLIDELNNFRQGLLKLFFMDYVCVPLVYTQVVTLSVYSYFIASLLGRQYIMESSPFSKEHNLRDLYFPFFTMLEFIIYMGWLKVAETLVNPMGEDDEDFDINEVIDFNWKTAWCIVDGMKPSPPAVVRDIHWHQSVVELPHTEESRRLLSRPCRGSVYDLNVQSTADYFGSGVSLHGGRRSQD---------------VRGRRLDSILSQLN---RFISSRGDEPDADQIDMEETELHAKVTS 432
BLAST of Bestrophin homolog vs. TrEMBL
Match: A0A0R3UIX4 (Bestrophin homolog OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS7414 PE=3 SV=1) HSP 1 Score: 343.584 bits (880), Expect = 1.953e-110 Identity = 165/367 (44.96%), Postives = 240/367 (65.40%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKN--RNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSK 1166
MTV+Y QDVLT GP+ FL+LL+RWKG + +LIY DF++F Y +S ++RF L + ++ FE+V+ YV Q +IP++FI+GFYV L+FSRFWQHFN++PW+ F P ++ + + + R +RT +RY+ +SL+I SR+ + K+RF L GIL + E LI+ +P QPFLP++W T+I ++A I N L+ +++ +N FR+ L LFL+D++CVPLVYTQVVTLA+YSYFLS ++GRQFI+ S + R D+ +P +TIL+FIVY+GW+K+A +LVNPMGEDDEDFD+N +ID N+ G+ V+ K +D F++S LP SK
Sbjct: 1 MTVQYNQDVLTGGPVVFLRLLLRWKGCVVKLIYVDFIVFMLAYAIVSCVYRFALTAEQQKNFESVVLYVFDFQQMIPISFILGFYVQLVFSRFWQHFNSVPWV---------------FTPTLAVIGAIQGEGRARTIRRTCVRYMNASLIIASSRLHVAAKKRFPTTQHLVQAGILTQREGDLIDSTDPVSAQPFLPLVWTTAIAMRAEKDGLIQNPHALVNLIQVVNNFRESLLRLFLMDKVCVPLVYTQVVTLAVYSYFLSSIIGRQFILDSSEYSSPFRKDYYVPFYTILEFIVYMGWLKVAETLVNPMGEDDEDFDINNIIDSNWSYGMHMVDK-KHHPTELVRDKFWDSSNVILPHTAGSK 351
BLAST of Bestrophin homolog vs. Ensembl Cavefish
Match: best1 (bestrophin-2 [Source:NCBI gene;Acc:103045999]) HSP 1 Score: 269.626 bits (688), Expect = 2.466e-81 Identity = 138/385 (35.84%), Postives = 219/385 (56.88%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFI-IVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNE 1223
MTV Y + V A F LL+RWKGSI++L+Y + L+F Y IS+++RF+L + +R FE + Y + LIPV+F++GFYV L+ SR+W F ++PW + A LV + ++ E RL +R+++RY S ++ +S V +RF I L G++ E ++ + ++P MW ++ ++A + RI N+ L I+ E+N R +L+ D I +PLVYTQVVT+A+YS+FL+CL+GRQF+ Y + DF +P+FT+LQF Y+GW+K+A L+NP GEDD+DF+ N L+D N Q + SV+ + P E+D ++N + P S +K + GS ++ + E
Sbjct: 1 MTVTYSRRVADARLGTFSHLLLRWKGSIYKLLYRELLIFTVLYCTISVLYRFLLDNEQRRLFEKLAIYCDQYAQLIPVSFVLGFYVTLVVSRWWGQFESVPWPDRLAALVGAY--------------VRGADEGARLIRRSLVRYANLSGVLIYRSISTAVYKRFPTIEHLVQAGLMTVEERRQLDDLPSPHNKFWVPCMWFVNLALRARTEGRINNDVALSAILNELNTLRSQCMKLYSYDWISLPLVYTQVVTVAVYSFFLACLIGRQFLDPTQGYSGHDLDFYLPVFTLLQFFFYVGWLKVAEQLINPFGEDDDDFETNWLVDRNLQVSLLSVDEMYDLVPLVERDKYWNESEPQPPYTAASAEHKKPSYMGSALDISVPKE 371
BLAST of Bestrophin homolog vs. Ensembl Cavefish
Match: best2 (bestrophin 2 [Source:ZFIN;Acc:ZDB-GENE-090312-127]) HSP 1 Score: 262.692 bits (670), Expect = 2.344e-79 Identity = 146/386 (37.82%), Postives = 218/386 (56.48%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSD-YLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRP-FRGSFCEMRIDNE 1223
MTV Y V A GF KLL+ W+GSI++++Y + L F Y AIS+ +RF L ++ KR FE + Y +LIP++F++GFYV LI +R+W + +IP ++S Q + E+ RL +RT++RY + L+ L VS V +RF ++ + G + E E + ++P +W T++ A + RI +++ ++EE+NKFR LF D I VPLVYTQVVTLA+YS+FL CL+GRQF+ S Y + D +PIFT+LQF Y GW+K+A L+NP GEDD+DF+ N LID NFQ + +V+ + P E+D ++N + P + F +P F+GS +M I E
Sbjct: 1 MTVTYTARVANARFCGFSKLLLAWRGSIYKVLYKEVLAFFILYTAISITYRFFLLDEQKRYFEKLSIYCNHYASLIPMSFVLGFYVTLIVNRWWSQYTSIPLPDSIMCVLSGGLQGGD--------------ERGRLLRRTLMRYASLASLLILRSVSTAVFKRFPTMDHVVEAGFMTREERKKFESLHSPYNKYWIPCVWFTNLAAVARSEGRIKDDNTYKLLLEELNKFRGKCSLLFHYDMISVPLVYTQVVTLAVYSFFLVCLIGRQFLDPSQAYPGHDLDLYVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWLIDRNFQVSMMAVDEMFGDLPMMERDRYWNDSNPRPPYTAATLFVLRKPSFQGSTFDMAIPKE 372
BLAST of Bestrophin homolog vs. Ensembl Cavefish
Match: best4 (bestrophin 4 [Source:ZFIN;Acc:ZDB-GENE-070912-6]) HSP 1 Score: 234.187 bits (596), Expect = 1.142e-71 Identity = 133/383 (34.73%), Postives = 212/383 (55.35%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQ-VVTLAIYSYFLSCLVGRQFII--VSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRP-FRGSFCEM 1208
MTV Y +V A GF KLL RWKGSI++L+Y +FLLF Y S+I+R +L + + FE + K LIP++F++ FYV F R+W + + P ++VS + E+ RL +RT++RY S ++ L +S V +RF + + + + E E ++ + ++P+ W ++ KA ++ R+ ++ L +++E+N +R LF D I +PLVYTQ VVTLA+YS+F CL+GRQF+ +D LK D +P+FT+L+F Y GW+K+ ++NP GEDD+DF+ N LID N Q + +V+++ + PP EKD ++ K + P F+ +P F GS +M
Sbjct: 1 MTVSYTLEVANARFAGFTKLLFRWKGSIYKLLYKEFLLFCFLYSLFSLIYRCVLTDGQQELFERAARHCNKFAKLIPMSFVL-FYVTQAFQRWWGQYTSFPLPDNLMMVVS--------------GNVHGSDERGRLLRRTLMRYANLSSVLILRSISTRVHKRFPTLQHIVD-AFMTEEEMRTLDHLYSDFNKYWMPLTWFANLASKAREEGRVKDDIALRLLMDELNNYRGKCSMLFHYDWISIPLVYTQQVVTLAVYSFFAFCLIGRQFVKPERADELKVHVDLYVPVFTLLEFFFYAGWLKVGELIINPFGEDDDDFETNQLIDRNIQVSMLAVDDMHQNLPPLEKDKYWTDKSFSRP------FSPAKPIFMGSTYDM 361
BLAST of Bestrophin homolog vs. Ensembl Cavefish
Match: best1 (bestrophin-2 [Source:NCBI gene;Acc:103045999]) HSP 1 Score: 231.876 bits (590), Expect = 1.714e-67 Identity = 126/385 (32.73%), Postives = 203/385 (52.73%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFI-IVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNE 1223
MTV Y + V A F LL+RWKGSI++L+Y + L+F Y IS+++RF+L + +R FE + Y + LIPV+F++GFYV L+ SR+W F ++PW + A LV + ++ E RL +R+++RY S ++ +S V +RF I L G++ E ++ + ++P MW ++ ++A + RI N+ L I+ VVT+A+YS+FL+CL+GRQF+ Y + DF +P+FT+LQF Y+GW+K+A L+NP GEDD+DF+ N L+D N Q + SV+ + P E+D ++N + P S +K + GS ++ + E
Sbjct: 1 MTVTYSRRVADARLGTFSHLLLRWKGSIYKLLYRELLIFTVLYCTISVLYRFLLDNEQRRLFEKLAIYCDQYAQLIPVSFVLGFYVTLVVSRWWGQFESVPWPDRLAALVGAY--------------VRGADEGARLIRRSLVRYANLSGVLIYRSISTAVYKRFPTIEHLVQAGLMTVEERRQLDDLPSPHNKFWVPCMWFVNLALRARTEGRINNDVALSAIL--------------------------NVVTVAVYSFFLACLIGRQFLDPTQGYSGHDLDFYLPVFTLLQFFFYVGWLKVAEQLINPFGEDDDDFETNWLVDRNLQVSLLSVDEMYDLVPLVERDKYWNESEPQPPYTAASAEHKKPSYMGSALDISVPKE 345
BLAST of Bestrophin homolog vs. Ensembl Cavefish
Match: BEST3 (bestrophin 3 [Source:HGNC Symbol;Acc:HGNC:17105]) HSP 1 Score: 143.28 bits (360), Expect = 5.688e-37 Identity = 73/208 (35.10%), Postives = 116/208 (55.77%), Query Frame = 3
Query: 594 GILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFI-IVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRI 1214
G + E + E + ++ ++P +W T++ KA RI + L I+ E+N+FR LF D + +PLVYTQVVTLA+Y++F + ++GRQF+ Y + D +P+FT+LQF Y GW+K+A L+NP GEDD+DF+ N ID N Q + +V+ + + P KD ++N + P + F GS +M +
Sbjct: 83 GFMTPEEKKIFENLKSPHLKYWIPTVWFTNLASKARKDGRIQDSVDLQTILTEMNRFRTWCSTLFGYDWVGIPLVYTQVVTLAVYTFFSASIIGRQFLDPAQGYPGHDLDLYVPVFTLLQFFFYSGWLKVAEQLINPFGEDDDDFEANWCIDRNLQVSLMAVDEMHMNIPRMTKDVYWNDPDVRPPYTRAAADYCIPSFLGSTTDMGL 290 HSP 2 Score: 76.6406 bits (187), Expect = 1.470e-14 Identity = 35/84 (41.67%), Postives = 54/84 (64.29%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGF 323
MTV Y V A GF +LL+RW+GSI++L+Y +FL FA Y +S+++R++L + +R FE + Y + IPV F++GF
Sbjct: 1 MTVTYSSKVANATFFGFHRLLLRWRGSIYKLLYREFLFFALLYSILSLVYRWVLTDPQRRLFEKLSIYCDRYAEQIPVTFVLGF 84
BLAST of Bestrophin homolog vs. Ensembl Sea Lamprey
Match: best1 (bestrophin 1 [Source:ZFIN;Acc:ZDB-GENE-110411-214]) HSP 1 Score: 265.003 bits (676), Expect = 4.520e-84 Identity = 135/380 (35.53%), Postives = 211/380 (55.53%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMR 1211
MTV Y V A GF +LL+RWKGSI++L+Y +F +F + +S ++R+ML E+ KR FE + Y K LIPV+F++GFYV L+ SR+W + ++PW + LV+ + E+ RL +RT++RY S L+ L VS V +RF ++ + G + E + + ++P +W ++ +A + RI + L I+ ++N FR L+ D + +PLVYTQVVT+A+YS+FL+CL+GRQF+ Y + D IP+FT+LQF Y GW+K+A L+NP GEDD+DF+ N +D N Q + V+ + PP E D +++ P S + F+GS ++R
Sbjct: 1 MTVTYSNKVANARLGGFSQLLLRWKGSIYKLLYKEFCIFLVLFFTLSSVYRYMLQENQKRYFEKLAMYCNKYAELIPVSFVLGFYVTLVVSRWWSQYESLPWPDRLMHLVAC--------------NVHGADERGRLLRRTLMRYANLSALLILRSVSTAVYKRFPTMDHVVEAGFMTPAERRKFDGLRSPHNKFWVPCVWFANLAAQAKAEGRILDNVSLQLILNDLNNFRSCCSMLYSYDWVSIPLVYTQVVTVAVYSFFLACLIGRQFLGPQGYPGHDMDLYIPVFTLLQFFFYAGWLKVAEQLINPFGEDDDDFEANWCVDRNLQVSLMGVDEMYRDLPPLEHDVYWDDISPCPPYTGASLVHHKASFQGSTFDVR 366
BLAST of Bestrophin homolog vs. Ensembl Sea Lamprey
Match: best2 (bestrophin 2 [Source:ZFIN;Acc:ZDB-GENE-090312-127]) HSP 1 Score: 256.914 bits (655), Expect = 2.818e-79 Identity = 148/447 (33.11%), Postives = 237/447 (53.02%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFII-VSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRP-FRGSFCEMRIDNENWIASIKSLLIDKESPDDGLLKS-VSNISKQPSPRIRRQTPMFSPINYVANLISSVKDESQ 1403
MTV Y V A GF KLL++W+GSI++L+Y +F ++ Y A+S+ RF L ED KR FE + Y LIPV GFYV L+ SR+W + +IP + V+ + E+ RL +RT++RY S L+ L VS V +RF ++ + G + E + + ++P +W +S+ +A + R+ ++ L +++E+N +R LF D I VPLVYTQVVT+A+YS+FL+CL+GRQF+ Y + D IP+FT+LQF Y GW+K+A L+NP GEDD+DF+ N LID N Q + +V+ + + P ++D ++N+ + P + +P F GS +M + ++ L D P LL+ + + PSP I R+ + ++ +A+ S + + +
Sbjct: 1 MTVTYTNRVANARLCGFSKLLLQWRGSIYKLLYREFSIYFMMYAALSLTSRFALSEDQKRLFEKLSLYCNNYANLIPVRSCSGFYVALVVSRWWSQYTSIPTPDRLMCAVAG--------------TVHGVDERGRLLRRTLMRYANLSALLILRSVSTAVYKRFPTMDHVVEAGFMTRDERKRFDGLRCSYNKYWVPCVWLSSLAAQARAEGRVRDDVALKLLLDEMNVYRGNCGMLFHYDWISVPLVYTQVVTVAVYSFFLACLIGRQFLDPAQGYPGHDMDLYIPVFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNLQVSMLAVDEMYQNLPLLQRDMYWNASDPRPPYTAATMSTLHKPSFLGSAFDMSMHKDDMEFQPMEQLSDPGMPVPQLLERLLHSRGSAPSPPITRRMNLVRRMDSIASSSSGIDEAGE 433
BLAST of Bestrophin homolog vs. Ensembl Medaka
Match: best2 (bestrophin 2 [Source:NCBI gene;Acc:110015962]) HSP 1 Score: 272.707 bits (696), Expect = 1.420e-83 Identity = 148/386 (38.34%), Postives = 218/386 (56.48%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRN-DFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRP-FRGSFCEMRIDNE 1223
MTV Y V A GF KLL+ WKGSI++++Y +FL F Y AIS+ +RF L ED KR FE + Y +LIP++F++GFYV LI +R+W + +IP + ++S Q E+ RL +R+++RY S L+ L VS V +RF ++ + G + E E + ++P +W T++ A + RI ++ L ++EE+N FR LF D + VPLVYTQVVTLA+YS+FL CL+GRQF+ S + + D +PIFT+LQF Y GW+K+A L+NP GEDD+DF+ N LID NFQ + +V+ + P E+D ++N + P + F +P F+GS +M I E
Sbjct: 1 MTVTYTARVANARFCGFSKLLLAWKGSIYKVLYKEFLAFFVLYAAISITYRFFLYEDQKRYFEKLAIYCNHYASLIPMSFVLGFYVTLIVNRWWNQYTSIPLPDRIMCVLSGGLQG--------------NDERGRLLRRSMMRYASLSALLILRSVSTAVFKRFPTMDHVVEAGFMTREERKKFEGLHSPYNKYWIPCVWFTNLAAVARCEGRIRDDHALKLLLEELNAFRGKCSLLFHYDMVSVPLVYTQVVTLAVYSFFLVCLIGRQFLDPSQGYQGHDLDLYVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWLIDRNFQVSMMAVDEMYGDLPVMERDRYWNDSNPRPPYTAATLFGLRKPSFQGSTFDMAIPKE 372
BLAST of Bestrophin homolog vs. Ensembl Medaka
Match: BEST3 (bestrophin 3 [Source:NCBI gene;Acc:101172121]) HSP 1 Score: 257.684 bits (657), Expect = 1.389e-77 Identity = 133/384 (34.64%), Postives = 214/384 (55.73%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRN-DFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDN 1220
MTV Y V A + F +LL+RW+GSI++L+Y +FLLFA Y +S+I+R L E KR FE + Y + IPV F++GFYV L+ +R+W F +PW + +S+ ++ + E RL +RT++RY+ + L+ VS V +RF I+ + G + E + E ++ ++PV+W +++ +A + RI + L I+ E+N FR LF D + +PLVYTQVVTLA+Y++F +C++GRQF+ + + D +P+FT+LQF Y GW+K+A L+NP GEDD+DF+ N +ID N Q + +V+ + + P KD ++N + P + F GS +M + +
Sbjct: 1 MTVTYSSKVANATFLSFHRLLLRWRGSIYKLLYREFLLFALLYTILSLIYRLALSEQQKRLFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFLNLPWPDRLMFHISSC--------------VQGKDEYGRLLRRTLVRYINLTSLLIFRSVSTAVCKRFPTIDHVVEAGFMTPEERKVFENIRSPHLKYWIPVVWFSNLASRARQEGRIQDAIDLQNILNEMNTFRTWCATLFGYDWVGIPLVYTQVVTLAVYTFFFACIIGRQFLDPAQGHPGHDLDLYVPVFTLLQFFFYSGWLKVAEQLINPFGEDDDDFEANWIIDRNLQVSLLAVDEMHMNLPHMTKDIYWNDSDARPPYTLAAADYCIPSFLGSTTDMGLSD 370
BLAST of Bestrophin homolog vs. Ensembl Medaka
Match: best1 (bestrophin-2 [Source:NCBI gene;Acc:101167866]) HSP 1 Score: 253.062 bits (645), Expect = 2.796e-75 Identity = 137/376 (36.44%), Postives = 211/376 (56.12%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFI-IVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGS 1196
MTV Y + V AG F LL+RWKGSI++L+Y + ++F Y +S+++ +ML D +R FE + Y + LIPV+F++ FYV L+ SR+W F IPW + A LV ++ E +RL +R ++RY+ S ++ VS V +RF L + E E P+ + ++P MW ++ ++A + RI N+ L I+ E+N R +L+ D I +PLVYTQV T+A+YS+FL+CL+GRQF+ Y + DF +P+FT+LQF Y+GW+K+A L+NP GEDD+DF+ N ++D N Q + SV+ + S P EKD ++N + P S ++ F GS
Sbjct: 1 MTVTYSRRVADAGLGTFFHLLLRWKGSIYKLLYRELIIFTLLYYFLSLVY-YMLDNDQRRLFERLSIYCDRYAELIPVSFVL-FYVTLVVSRWWGQFENIPWPDRLAALVG--------------GHVRGTDEASRLTRRALMRYVNLSGVLIYRSVSTAVYKRFPTTEHLVQALMTSEELRHFEELPSPH-NKFWVPCMWFVNLALRARTEGRINNDVALTAILTELNSLRAKCMKLYGYDWISLPLVYTQVATVAVYSFFLACLIGRQFLDPAQGYPGHDVDFYLPVFTLLQFFFYVGWLKVAEQLINPFGEDDDDFETNWVVDRNLQVSLLSVDEMYDSLPLVEKDVYWNDSEPQPPYTAASAEHRKPSFMGS 359
BLAST of Bestrophin homolog vs. Planmine SMEST
Match: SMESG000030927.1 (SMESG000030927.1) HSP 1 Score: 939.873 bits (2428), Expect = 0.000e+0 Identity = 469/487 (96.30%), Postives = 471/487 (96.71%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNENWIASIKSLLIDKESPDDGLLKSVSNISKQPSPRIRRQTPMFSPINYVANLISSVKDESQPEITSSEEVSEPRKKSSEKYSLLAIVEEDSASSHEIKINVSSH 1532
MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSD LLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPV+ IPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNENWIASIKSLLIDKE+PDDGLLKSVSNISKQPSPRIRRQTPMFSPINYVANLISSVKDESQPEITSSE VSEPRKKSSEKYSLLAIVEEDSASSHEIKINVSSH
Sbjct: 1 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDLLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVI--------------IPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNENWIASIKSLLIDKETPDDGLLKSVSNISKQPSPRIRRQTPMFSPINYVANLISSVKDESQPEITSSEVVSEPRKKSSEKYSLLAIVEEDSASSHEIKINVSSH 473
BLAST of Bestrophin homolog vs. Planmine SMEST
Match: SMESG000030927.1 (SMESG000030927.1) HSP 1 Score: 848.581 bits (2191), Expect = 0.000e+0 Identity = 441/487 (90.55%), Postives = 442/487 (90.76%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNENWIASIKSLLIDKESPDDGLLKSVSNISKQPSPRIRRQTPMFSPINYVANLISSVKDESQPEITSSEEVSEPRKKSSEKYSLLAIVEEDSASSHEIKINVSSH 1532
MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSD LLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHES EEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNENWIASIKSLLIDKE+PDDGLLKSVSNISKQPSPRIRRQTPMFSPINYVANLISSVKDESQPEITSSE VSEPRKKSSEKYSLLAIVEEDSASSHEIKINVSSH
Sbjct: 1 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDLLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHES-------------------------------------------EEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNENWIASIKSLLIDKETPDDGLLKSVSNISKQPSPRIRRQTPMFSPINYVANLISSVKDESQPEITSSEVVSEPRKKSSEKYSLLAIVEEDSASSHEIKINVSSH 444
BLAST of Bestrophin homolog vs. Planmine SMEST
Match: SMESG000030918.1 (SMESG000030918.1) HSP 1 Score: 541.576 bits (1394), Expect = 0.000e+0 Identity = 264/501 (52.69%), Postives = 370/501 (73.85%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRIDNENWIASIKSLLIDKESP--DDGL----LKSVSNISKQPSPRIRRQTPMF------SPINYVANLISSVKDESQPEITSS-----EEVSEPRK--KSSEKYSLLAIVEEDSASSHEIKI 1517
MTV+YYQ+VL+AGP+ FLKLL +WKG +F+LIY DF++F++ Y IS I+R +L +++KRQFE V++YV +SQ+LIPVAFI+GFYV+L+F+RFW+HFNT+PWI+K A+++++ ++ I+K+KE+ RLQ+R+IIRYL +SL+ITLSRVS+PVKRRF NI+E+ NKGILLEHE+ +I+ EP+ MQPFLP+ W+ +I++KA + RI NE++LI V+EINKFRQLLQELFLLDQ+CVPLVYTQVVTLA+YSYFLSCL+GRQFI+ S ++ DFV+PIFTILQFIVY+GW+KLAL+LVNPMGEDDEDFDLN ++DYNF+ G++ + +K QPP KD FF+ K+++LP+ K + +PF GS +M++D+ +WI S+KS+ I E +D L L+ +S+ S R Q MF S + ++ S+ + IT + EE+ EP KS+EK+ LL I EE+ + +EI++
Sbjct: 1 MTVQYYQEVLSAGPVAFLKLLRKWKGGVFKLIYMDFIVFSSLYTMISCIYRLILRDEHKRQFEKVVSYVYQSQSLIPVAFILGFYVSLVFNRFWRHFNTVPWITKIAIMIASHMNTVSPANSGDDESIRKDKEEARLQRRSIIRYLTASLIITLSRVSVPVKRRFPNIDEIFNKGILLEHEAEIIKNTEPFTMQPFLPITWSATIVMKAGTQGRITNEAVLINTVKEINKFRQLLQELFLLDQVCVPLVYTQVVTLAVYSYFLSCLIGRQFIMDSVNVETTQDFVVPIFTILQFIVYMGWLKLALTLVNPMGEDDEDFDLNCVVDYNFEIGLAIADGVKIDQPPLIKDKFFDKKVFELPMESNMKDARAKPFMGSVYDMKVDSNDWITSLKSIAIGSEGELRNDKLYIQSLEDKKGVSRNNSN--RSQKSMFTKKRTISTSSGISMFTSTASLKGLEAITPTISKMPEEIDEPPTPVKSNEKHPLLVIEEEEQSQGNEIEL 499
BLAST of Bestrophin homolog vs. Planmine SMEST
Match: SMESG000054993.1 (SMESG000054993.1) HSP 1 Score: 234.187 bits (596), Expect = 2.537e-71 Identity = 131/382 (34.29%), Postives = 216/382 (56.54%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFIIVSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKLPLNEKSKFNKTRPFRGSFCEMRID 1217
MT+ Y V T+ FL+LL+RWKGSI+++I+ + ++FA Y +S ++RF L K++FE + K+ +IPV F++GFYV L+ SR+W F IPW A+ VSTF I +K+ + +RTI+RYL S +T + +S KR F ++ L G+L + E ++ + E + F+P +WA++++ +A +K E + ++EEI KFR L ++ D I PLVYTQ+ T+++++YF+ + QFI K++ D +P+F LQF+ Y+GW+K+A SL+NP G+DD+DF+++ +I N + ++ + S P +KD F+NS + + K K F GS + D
Sbjct: 1 MTITYINTVATSKYWTFLRLLLRWKGSIYKIIWFEMIVFATLYTGLSCLYRFGLYGIYKKRFEEFCAFSKKNADMIPVPFVLGFYVTLVVSRWWNQFMEIPWPDSMAIYVSTF--------------ILGNDDKSVMYRRTIMRYLNLSFCMTFASISSKAKRMFPDLKTLIENGLLTKDEEKILNEYETNNAKYFVPALWASNLVYQAESEKMTIGERGVETLIEEIGKFRGSLGMIYCFDWINPPLVYTQIATISVHAYFMIFVFAEQFI-----SKDKVDVYVPMFGFLQFVFYMGWLKVAESLINPFGDDDDDFEIDEMIHRNIKMSYLIIDEMHDSYPELDKDVFWNSN-RDIQIIHDYKSPKNDMFAGSLLNLNTD 362
BLAST of Bestrophin homolog vs. Planmine SMEST
Match: SMESG000069980.1 (SMESG000069980.1) HSP 1 Score: 211.075 bits (536), Expect = 6.230e-63 Identity = 119/360 (33.06%), Postives = 195/360 (54.17%), Query Frame = 3
Query: 72 MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHRFMLPEDNKRQFETVINYVAKSQALIPVAFIVGFYVNLIFSRFWQHFNTIPWISKTALLVSTFFQDPEFNPEMSEDEIKKEKEKTRLQKRTIIRYLVSSLLITLSRVSIPVKRRFKNINELSNKGILLEHESGLIEKCEPYIMQPFLPVMWATSIIIKASDKKRIPNESLLIGIVEEINKFRQLLQELFLLDQICVPLVYTQVVTLAIYSYFLSCLVGRQFII--VSDYLKNRNDFVIPIFTILQFIVYIGWIKLALSLVNPMGEDDEDFDLNTLIDYNFQTGISSVENLKSSQPPFEKDFFFNSKIYKL 1145
MTV Y + T+ KLL+ WKGSI++ I + ++ IS++H F L + FE+ ++ AK IPV ++GFYV L+ R+ F T+PW A+ V+TF I + RL +R+I+RY++ S ++ S +S KR F L +G+L E +EK E + F+P+ WA +++KA +K + + + + E+N+FR L+ LF D I PL+YTQ+ + +YSYF+ + G+QFII S N +V P+F L+FI Y+GW+K+A L+NP G+D++DF+++ +I NF+ +V+ PP ++D ++ K +L
Sbjct: 1 MTVSYVSKIATSNSFRVFKLLLTWKGSIYKTIRIELFIYIVLNALISLLHYF-LTGYYRLIFESFCSFCAKGTGFIPVGLVLGFYVTLVVQRWTDQFVTLPWPDSLAVYVNTF--------------ILGAGDTPRLIRRSIMRYVIVSQILCYSSISSKAKRVFSTNQTLVEQGLLTTEELSRLEKFETTSNKHFVPIAWAQELVVKAQKEKYLMDNKRVWLLANELNEFRDRLRILFAYDWINPPLIYTQIAIITMYSYFIFSIFGKQFIIHGTSQSAHGMNLYV-PVFGALEFINYMGWLKVAQCLINPFGDDEDDFEMDQIILRNFEYSFITVDQWHQQCPPLQQDMYYLQKNARL 344 The following BLAST results are available for this feature:
BLAST of Bestrophin homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Bestrophin homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Bestrophin homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Bestrophin homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Bestrophin homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Bestrophin homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Bestrophin homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Bestrophin homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Bestrophin homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Bestrophin homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of Bestrophin homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Bestrophin homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of Bestrophin homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 3
BLAST of Bestrophin homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002988 ID=SMED30002988|Name=Bestrophin homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=1663bpback to top protein sequence of SMED30002988-orf-1 >SMED30002988-orf-1 ID=SMED30002988-orf-1|Name=SMED30002988-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=488bp MTVKYYQDVLTAGPIGFLKLLIRWKGSIFRLIYSDFLLFAAFYMAISMIHback to top Annotated Terms
The following terms have been associated with this transcript:
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