Actin-related protein 2/3 complex subunit 3

Overview
NameActin-related protein 2/3 complex subunit 3
Smed IDSMED30002941
Length (bp)696
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Actin-related protein 2/3 complex subunit 3 (SMED30002941) t-SNE clustered cells

Violin plots show distribution of expression levels for Actin-related protein 2/3 complex subunit 3 (SMED30002941) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Actin-related protein 2/3 complex subunit 3 (SMED30002941) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Actin-related protein 2/3 complex subunit 3 (SMED30002941) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30002941

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30002941h1SMcG0001999 Contig32GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30002941h1SMcG0001999 Contig32GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30002941h1SMcG0001999 dd_Smed_v4_619_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30002941h1SMcG0001999 dd_Smed_v4_619_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30002941h1SMcG0001999 dd_Smed_v4_619_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30002941h1SMcG0001999 dd_Smed_v4_619_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Human
Match: ARPC3 (actin related protein 2/3 complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:706])

HSP 1 Score: 196.052 bits (497), Expect = 3.783e-63
Identity = 94/181 (51.93%), Postives = 134/181 (74.03%), Query Frame = 3 
Query:   75 AYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS   + +   I +MALLP++++F+GPAP +      DI+DE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGEKE+ +LGI NF +PG+PGFP  L+  Y KP +  E E ++AY+QQLRQE   R+ EK+F    ++ PSKWW CF K++F++K+LS PG+
Sbjct:    3 AYHSSLMDPDTKLIGNMALLPIRSQFKGPAPRETKDT--DIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFP--LNAIYAKPANKQEDEVMRAYLQQLRQETGLRLCEKVF-DPQNDKPSKWWTCFVKRQFMNKSLSGPGQ 178
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Human
Match: ARPC3 (actin related protein 2/3 complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:706])

HSP 1 Score: 99.3673 bits (246), Expect = 1.548e-26
Identity = 45/79 (56.96%), Postives = 64/79 (81.01%), Query Frame = 3 
Query:  111 ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGE 347
            I +MALLP++++F+GPAP +      DI+DE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGE
Sbjct:    8 IGNMALLPIRSQFKGPAPRETKDT--DIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGE 84
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Human
Match: ARPC3 (actin related protein 2/3 complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:706])

HSP 1 Score: 98.5969 bits (244), Expect = 5.518e-26
Identity = 47/90 (52.22%), Postives = 68/90 (75.56%), Query Frame = 3 
Query:   75 AYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQ 341
            AYHS   + +   I +MALLP++++F+GPAP +      DI+DE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ Q
Sbjct:    3 AYHSSLMDPDTKLIGNMALLPIRSQFKGPAPRETKDT--DIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQ 90
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Celegans
Match: arx-5 (Probable actin-related protein 2/3 complex subunit 3 [Source:UniProtKB/Swiss-Prot;Acc:Q9XWV3])

HSP 1 Score: 147.902 bits (372), Expect = 1.367e-44
Identity = 77/184 (41.85%), Postives = 123/184 (66.85%), Query Frame = 3 
Query:   75 AYHSEF-TEFNA---SICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFS-MPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPG 611
            AYHS+F TE         +M  LP++T F+GPAP     N  DIIDE++  FK  +FF+ FEI+  ADR ++YL+ YI ECL+ LQK  N++ G+K+L++L +++   +PG+ GFP  L++ Y  P+   + ++++AY+QQ+RQE+ +R+ +  FP    + PSKWW+CF++++F+DK L   G
Sbjct:    3 AYHSKFDTELKVLPLGNTNMGKLPIRTNFKGPAPQT---NQDDIIDEALTYFKPNIFFREFEIKGPADRTMIYLIFYITECLRKLQKSPNKIAGQKDLHALALSHLLPIPGENGFP--LNSMYKAPQSKPDEDEMRAYLQQIRQEIGARLCDLAFP-DPQDRPSKWWLCFARRRFMDKGLVGQG 180
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Fly
Match: Arpc3B (gene:FBgn0065032 transcript:FBtr0074410)

HSP 1 Score: 193.356 bits (490), Expect = 2.205e-62
Identity = 93/179 (51.96%), Postives = 132/179 (73.74%), Query Frame = 3 
Query:   75 AYHSEFTEFNASICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPG 611
            A+HSE  +F AS+ +MALLPL+T+ RGPAPT    N  DIIDES+Y +KS +FF+ +E++S+ DRVL+Y+ LYI ECLK L +C+++ QG++EL +L I+ F +PGD GFP  L+  Y KP+D    E ++ Y  QLRQE  +R++EK+F  +    PSKWW+CF+KKKF++K+LS PG
Sbjct:    3 AFHSEIEDFQASVGNMALLPLRTQVRGPAPTVDIPN--DIIDESLYFWKSNIFFRTYEVKSEVDRVLIYITLYITECLKRLARCTSKSQGQQELYTLAISRFDIPGDAGFP--LNGIYTKPED---PELMRQYFLQLRQETGNRLLEKVF-DTPDGKPSKWWICFAKKKFMEKSLSGPG 173
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Fly
Match: Arpc3A (gene:FBgn0038369 transcript:FBtr0300570)

HSP 1 Score: 186.037 bits (471), Expect = 1.379e-59
Identity = 84/180 (46.67%), Postives = 129/180 (71.67%), Query Frame = 3 
Query:   75 AYHSEFTEFNASICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS+  E    + +MA+LPL+T+ RGPAP+   ++  DIIDES+Y FK+ VFF+ +EI+SD DRVL+Y+ LYI ECLK L + +++ QG++++ SL I+ F +PGD GFP  L+  Y KP+   + + ++ Y+ QLR E  +R++EK+F  +    P+KWW CF+KKKF++K+L+ PG+
Sbjct:    3 AYHSQIKEVRQQVGNMAILPLRTQVRGPAPSANIES--DIIDESLYYFKANVFFRTYEIKSDVDRVLIYVTLYITECLKKLNRSTSKAQGQQDMYSLAISKFDIPGDAGFP--LNAVYAKPQTAQDADLMRQYLLQLRHETGNRVLEKVF-NTEDGKPNKWWTCFAKKKFMEKSLAGPGQ 177
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Fly
Match: Arpc3A (gene:FBgn0038369 transcript:FBtr0334594)

HSP 1 Score: 186.037 bits (471), Expect = 1.379e-59
Identity = 84/180 (46.67%), Postives = 129/180 (71.67%), Query Frame = 3 
Query:   75 AYHSEFTEFNASICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS+  E    + +MA+LPL+T+ RGPAP+   ++  DIIDES+Y FK+ VFF+ +EI+SD DRVL+Y+ LYI ECLK L + +++ QG++++ SL I+ F +PGD GFP  L+  Y KP+   + + ++ Y+ QLR E  +R++EK+F  +    P+KWW CF+KKKF++K+L+ PG+
Sbjct:    3 AYHSQIKEVRQQVGNMAILPLRTQVRGPAPSANIES--DIIDESLYYFKANVFFRTYEIKSDVDRVLIYVTLYITECLKKLNRSTSKAQGQQDMYSLAISKFDIPGDAGFP--LNAVYAKPQTAQDADLMRQYLLQLRHETGNRVLEKVF-NTEDGKPNKWWTCFAKKKFMEKSLAGPGQ 177
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Fly
Match: Arpc3B (gene:FBgn0065032 transcript:FBtr0113478)

HSP 1 Score: 176.022 bits (445), Expect = 6.652e-56
Identity = 86/164 (52.44%), Postives = 121/164 (73.78%), Query Frame = 3 
Query:  120 MALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPG 611
            MALLPL+T+ RGPAPT    N  DIIDES+Y +KS +FF+ +E++S+ DRVL+Y+ LYI ECLK L +C+++ QG++EL +L I+ F +PGD GFP  L+  Y KP+D    E ++ Y  QLRQE  +R++EK+F  +    PSKWW+CF+KKKF++K+LS PG
Sbjct:    1 MALLPLRTQVRGPAPTVDIPN--DIIDESLYFWKSNIFFRTYEVKSEVDRVLIYITLYITECLKRLARCTSKSQGQQELYTLAISRFDIPGDAGFP--LNGIYTKPED---PELMRQYFLQLRQETGNRLLEKVF-DTPDGKPSKWWICFAKKKFMEKSLSGPG 156
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Fly
Match: Arpc3B (gene:FBgn0065032 transcript:FBtr0334462)

HSP 1 Score: 176.022 bits (445), Expect = 6.652e-56
Identity = 86/164 (52.44%), Postives = 121/164 (73.78%), Query Frame = 3 
Query:  120 MALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPG 611
            MALLPL+T+ RGPAPT    N  DIIDES+Y +KS +FF+ +E++S+ DRVL+Y+ LYI ECLK L +C+++ QG++EL +L I+ F +PGD GFP  L+  Y KP+D    E ++ Y  QLRQE  +R++EK+F  +    PSKWW+CF+KKKF++K+LS PG
Sbjct:    1 MALLPLRTQVRGPAPTVDIPN--DIIDESLYFWKSNIFFRTYEVKSEVDRVLIYITLYITECLKRLARCTSKSQGQQELYTLAISRFDIPGDAGFP--LNGIYTKPED---PELMRQYFLQLRQETGNRLLEKVF-DTPDGKPSKWWICFAKKKFMEKSLSGPG 156
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Zebrafish
Match: arpc3 (actin related protein 2/3 complex, subunit 3 [Source:ZFIN;Acc:ZDB-GENE-040625-107])

HSP 1 Score: 198.749 bits (504), Expect = 2.138e-64
Identity = 96/181 (53.04%), Postives = 133/181 (73.48%), Query Frame = 3 
Query:   75 AYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS   + +   + +MALLPLKT+F+GPA  +      DIIDE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKCS+R QGEKE+ +LGI NF +PG+PGFP  L+  Y KP    E E ++AY+QQ+RQE   R+ +++F    ++ PSKWW+CF KK+F++K+LS PG+
Sbjct:    3 AYHSALMDADTKLVGNMALLPLKTQFKGPAARETKDT--DIIDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCSSRGQGEKEMYTLGITNFPIPGEPGFP--LNAMYAKPSSKQEEENMRAYLQQIRQETGLRLCDRVF-DPQTDKPSKWWVCFVKKQFMNKSLSAPGQ 178
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Xenopus
Match: arpc3 (actin related protein 2/3 complex subunit 3 [Source:NCBI gene;Acc:100038232])

HSP 1 Score: 197.593 bits (501), Expect = 8.208e-64
Identity = 94/183 (51.37%), Postives = 137/183 (74.86%), Query Frame = 3 
Query:   69 SMAYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            + AYHS   E +   I +MA+LP++++F+GPAP +      DIIDE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGEKE+ +LGI NF +PG+PGFP  L+  Y+KP +  E E ++AY+QQLRQE   R+ +K+F    ++ PSKWW+CF K++F++K+LS PG+
Sbjct:    4 TRAYHSMLMESDTKLIGNMAMLPIRSQFKGPAPRETKDT--DIIDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKGQGEKEMYTLGITNFPIPGEPGFP--LNAMYVKPSNKQEDEVMRAYLQQLRQETGLRLCDKVF-DPQTDKPSKWWICFVKRQFMNKSLSGPGQ 181
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Xenopus
Match: arpc3 (actin related protein 2/3 complex subunit 3 [Source:NCBI gene;Acc:100038232])

HSP 1 Score: 197.208 bits (500), Expect = 1.116e-63
Identity = 94/181 (51.93%), Postives = 136/181 (75.14%), Query Frame = 3 
Query:   75 AYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS   E +   I +MA+LP++++F+GPAP +      DIIDE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGEKE+ +LGI NF +PG+PGFP  L+  Y+KP +  E E ++AY+QQLRQE   R+ +K+F    ++ PSKWW+CF K++F++K+LS PG+
Sbjct:    3 AYHSMLMESDTKLIGNMAMLPIRSQFKGPAPRETKDT--DIIDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKGQGEKEMYTLGITNFPIPGEPGFP--LNAMYVKPSNKQEDEVMRAYLQQLRQETGLRLCDKVF-DPQTDKPSKWWICFVKRQFMNKSLSGPGQ 178
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Mouse
Match: Arpc3 (actin related protein 2/3 complex, subunit 3 [Source:MGI Symbol;Acc:MGI:1928375])

HSP 1 Score: 197.593 bits (501), Expect = 6.574e-64
Identity = 96/181 (53.04%), Postives = 133/181 (73.48%), Query Frame = 3 
Query:   75 AYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS   + +   I +MALLPL+++F+GPAP +      DI+DE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGEKE+ +LGI NF +PG+PGFP  L+  Y KP    E E ++AY+QQLRQE   R+ EK+F    S+ PSKWW CF K++F++K+LS PG+
Sbjct:    3 AYHSSLMDPDTKLIGNMALLPLRSQFKGPAPRETKDT--DIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFP--LNAIYAKPASKQEDEMMRAYLQQLRQETGLRLCEKVF-DPQSDKPSKWWTCFVKRQFMNKSLSGPGQ 178
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Mouse
Match: Arpc3 (actin related protein 2/3 complex, subunit 3 [Source:MGI Symbol;Acc:MGI:1928375])

HSP 1 Score: 192.971 bits (489), Expect = 3.032e-62
Identity = 92/168 (54.76%), Postives = 127/168 (75.60%), Query Frame = 3 
Query:  111 ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            I +MALLPL+++F+GPAP +      DI+DE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGEKE+ +LGI NF +PG+PGFP  L+  Y KP    E E ++AY+QQLRQE   R+ EK+F    S+ PSKWW CF K++F++K+LS PG+
Sbjct:    8 IGNMALLPLRSQFKGPAPRETKDT--DIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFP--LNAIYAKPASKQEDEMMRAYLQQLRQETGLRLCEKVF-DPQSDKPSKWWTCFVKRQFMNKSLSGPGQ 170
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Mouse
Match: Arpc3 (actin related protein 2/3 complex, subunit 3 [Source:MGI Symbol;Acc:MGI:1928375])

HSP 1 Score: 172.17 bits (435), Expect = 4.721e-54
Identity = 80/142 (56.34%), Postives = 109/142 (76.76%), Query Frame = 3 
Query:  189 DIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            DI+DE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGEKE+ +LGI NF +PG+PGFP  L+  Y KP    E E ++AY+QQLRQE   R+ EK+F    S+ PSKWW CF K++F++K+LS PG+
Sbjct:   25 DIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFP--LNAIYAKPASKQEDEMMRAYLQQLRQETGLRLCEKVF-DPQSDKPSKWWTCFVKRQFMNKSLSGPGQ 163
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Mouse
Match: Arpc3 (actin related protein 2/3 complex, subunit 3 [Source:MGI Symbol;Acc:MGI:1928375])

HSP 1 Score: 171.785 bits (434), Expect = 5.218e-54
Identity = 80/142 (56.34%), Postives = 109/142 (76.76%), Query Frame = 3 
Query:  189 DIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            DI+DE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGEKE+ +LGI NF +PG+PGFP  L+  Y KP    E E ++AY+QQLRQE   R+ EK+F    S+ PSKWW CF K++F++K+LS PG+
Sbjct:   23 DIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFP--LNAIYAKPASKQEDEMMRAYLQQLRQETGLRLCEKVF-DPQSDKPSKWWTCFVKRQFMNKSLSGPGQ 161
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Mouse
Match: Arpc3 (actin related protein 2/3 complex, subunit 3 [Source:MGI Symbol;Acc:MGI:1928375])

HSP 1 Score: 162.925 bits (411), Expect = 8.093e-51
Identity = 80/146 (54.79%), Postives = 108/146 (73.97%), Query Frame = 3 
Query:  123 ALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWW 560
            ALLPL+++F+GPAP +      DI+DE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGEKE+ +LGI NF +PG+PGFP  L+  Y KP    E E ++AY+QQLRQE   R+ EK+F    S+ PSK W
Sbjct:    2 ALLPLRSQFKGPAPRETKDT--DIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFP--LNAIYAKPASKQEDEMMRAYLQQLRQETGLRLCEKVF-DPQSDKPSKGW 142
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q7T0U5|ARC3B_XENLA (Actin-related protein 2/3 complex subunit 3-B OS=Xenopus laevis OX=8355 GN=arpc3-b PE=2 SV=1)

HSP 1 Score: 197.593 bits (501), Expect = 4.169e-63
Identity = 95/181 (52.49%), Postives = 136/181 (75.14%), Query Frame = 3 
Query:   75 AYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS   E +   I +MA+LP++++F+GPAP +      DIIDE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGEKE+ +LGI NF +PG+PGFP  L+  Y+KP +  E E ++AY+QQLRQE   R+ +K+F    ++ PSKWW+CF KK+F++K+LS PG+
Sbjct:    3 AYHSILMESDTKLIGNMAMLPIRSQFKGPAPRETKDT--DIIDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKGQGEKEMYTLGITNFPIPGEPGFP--LNAMYVKPSNKQEDEVMRAYLQQLRQETGLRLCDKVF-DPQTDKPSKWWICFVKKQFMNKSLSGPGQ 178
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q9JM76|ARPC3_MOUSE (Actin-related protein 2/3 complex subunit 3 OS=Mus musculus OX=10090 GN=Arpc3 PE=1 SV=3)

HSP 1 Score: 197.593 bits (501), Expect = 4.599e-63
Identity = 96/181 (53.04%), Postives = 133/181 (73.48%), Query Frame = 3 
Query:   75 AYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS   + +   I +MALLPL+++F+GPAP +      DI+DE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGEKE+ +LGI NF +PG+PGFP  L+  Y KP    E E ++AY+QQLRQE   R+ EK+F    S+ PSKWW CF K++F++K+LS PG+
Sbjct:    3 AYHSSLMDPDTKLIGNMALLPLRSQFKGPAPRETKDT--DIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFP--LNAIYAKPASKQEDEMMRAYLQQLRQETGLRLCEKVF-DPQSDKPSKWWTCFVKRQFMNKSLSGPGQ 178
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. UniProt/SwissProt
Match: sp|O15145|ARPC3_HUMAN (Actin-related protein 2/3 complex subunit 3 OS=Homo sapiens OX=9606 GN=ARPC3 PE=1 SV=3)

HSP 1 Score: 196.052 bits (497), Expect = 1.817e-62
Identity = 94/181 (51.93%), Postives = 134/181 (74.03%), Query Frame = 3 
Query:   75 AYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS   + +   I +MALLP++++F+GPAP +      DI+DE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGEKE+ +LGI NF +PG+PGFP  L+  Y KP +  E E ++AY+QQLRQE   R+ EK+F    ++ PSKWW CF K++F++K+LS PG+
Sbjct:    3 AYHSSLMDPDTKLIGNMALLPIRSQFKGPAPRETKDT--DIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFP--LNAIYAKPANKQEDEVMRAYLQQLRQETGLRLCEKVF-DPQNDKPSKWWTCFVKRQFMNKSLSGPGQ 178
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q3T035|ARPC3_BOVIN (Actin-related protein 2/3 complex subunit 3 OS=Bos taurus OX=9913 GN=ARPC3 PE=1 SV=3)

HSP 1 Score: 196.052 bits (497), Expect = 1.817e-62
Identity = 94/181 (51.93%), Postives = 134/181 (74.03%), Query Frame = 3 
Query:   75 AYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS   + +   I +MALLP++++F+GPAP +      DI+DE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGEKE+ +LGI NF +PG+PGFP  L+  Y KP +  E E ++AY+QQLRQE   R+ EK+F    ++ PSKWW CF K++F++K+LS PG+
Sbjct:    3 AYHSSLMDPDTKLIGNMALLPIRSQFKGPAPRETKDT--DIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFP--LNAIYAKPANKQEDEVMRAYLQQLRQETGLRLCEKVF-DPQNDKPSKWWTCFVKRQFMNKSLSGPGQ 178
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. UniProt/SwissProt
Match: sp|A1DPK7|ARC3A_XENLA (Actin-related protein 2/3 complex subunit 3-A OS=Xenopus laevis OX=8355 GN=arpc3-a PE=1 SV=1)

HSP 1 Score: 195.667 bits (496), Expect = 2.690e-62
Identity = 94/181 (51.93%), Postives = 135/181 (74.59%), Query Frame = 3 
Query:   75 AYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS   E +   I +MA+LP++++F+GPAP +      DIIDE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKC+++ QGEKE+ +LGI NF +PG+PGFP  L+  Y+KP +  E E ++AY+QQLRQE   R+ +K+F    ++ PSKWW CF K++F++K+LS PG+
Sbjct:    3 AYHSMLMEPDTKLIGNMAMLPIRSQFKGPAPRETKDT--DIIDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKGQGEKEMYTLGITNFPIPGEPGFP--LNAMYVKPSNKQEDEVMRAYLQQLRQETGLRLCDKVF-DPQTDKPSKWWTCFVKRQFMNKSLSAPGQ 178
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. TrEMBL
Match: A0A4S2M892 (Actin-related protein 2/3 complex subunit 3 OS=Opisthorchis felineus OX=147828 GN=CRM22_001992 PE=3 SV=1)

HSP 1 Score: 227.639 bits (579), Expect = 2.662e-72
Identity = 101/179 (56.42%), Postives = 142/179 (79.33%), Query Frame = 3 
Query:   75 AYHSEFTEFNASICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPG 611
            +YHS+F +  +++ +MALLPL+TKFRGPAP   D   +DIIDE++YLFKSL+F + +EI+S+ADRVL+YLVLY ++CLK +QKCSN++   KEL SL +A F +PGDPGFP+EL+N Y KPK+ +E + ++ Y+ QLRQE+ SR++E ++PG    PPSKWW CFSK++FLD+ L+ PG
Sbjct:    3 SYHSQFVQAPSTVGNMALLPLRTKFRGPAPAMPDLE-KDIIDEALYLFKSLIFLRQYEIKSEADRVLVYLVLYTLDCLKKIQKCSNKIVATKELASLALARFDIPGDPGFPRELNNLYAKPKNQSESDAMRNYITQLRQELGSRLVELVYPGDNC-PPSKWWTCFSKRRFLDQTLTPPG 179
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. TrEMBL
Match: A0A267ET16 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022851g1 PE=4 SV=1)

HSP 1 Score: 227.639 bits (579), Expect = 3.073e-72
Identity = 100/185 (54.05%), Postives = 144/185 (77.84%), Query Frame = 3 
Query:   60 FLISMAYHSEFTEFNASICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
             L+  AYHSEF +    + +MALLPL+TKFRGPAP + +   +DIIDE+++ FK+ VFFKN+EI+S+ADRVL+YL LYI++ LK + +C N+ Q  KE+N++GIA F +PGDPGFP+EL+  Y KP+D  E + ++ Y+QQLRQE   R++E++FPG+ +E PSKWW+CFSK+KF+D+ L+ PG+
Sbjct:    1 LLVMPAYHSEFVQPPKLVGNMALLPLRTKFRGPAPQEANLE-KDIIDEALFYFKANVFFKNYEIKSEADRVLIYLTLYILDVLKKVHRCQNKNQAAKEINAMGIAKFDIPGDPGFPRELNAMYAKPRDRAEDDAMRQYIQQLRQETGQRLLERLFPGNPNEKPSKWWICFSKRKFMDQTLTRPGQ 184
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. TrEMBL
Match: A0A1I8GBR6 (Actin-related protein 2/3 complex subunit 3 OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 225.713 bits (574), Expect = 1.386e-71
Identity = 99/180 (55.00%), Postives = 142/180 (78.89%), Query Frame = 3 
Query:   75 AYHSEFTEFNASICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHSEF +    + +MALLPL+TKFRGPAP + +   +DIIDE+++ FK+ VFFKN+EI+S+ADRVL+YL LYI++ LK + +C N+ Q  KE+N++GIA F +PGDPGFP+EL+  Y KP+D  E + ++ Y+QQLRQE   R++E++FPG+ +E PSKWW+CFSK+KF+D+ L+ PG+
Sbjct:    3 AYHSEFVQPPKLVGNMALLPLRTKFRGPAPQEANLE-KDIIDEALFYFKANVFFKNYEIKSEADRVLIYLTLYILDVLKKVHRCQNKNQAAKEINAMGIAKFDIPGDPGFPRELNAMYAKPRDRAEDDAMRQYIQQLRQETGQRLLERLFPGNPNEKPSKWWICFSKRKFMDQTLTRPGQ 181
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. TrEMBL
Match: A0A1I8J554 (Actin-related protein 2/3 complex subunit 3 OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006309g1 PE=3 SV=1)

HSP 1 Score: 224.942 bits (572), Expect = 2.612e-71
Identity = 99/180 (55.00%), Postives = 141/180 (78.33%), Query Frame = 3 
Query:   75 AYHSEFTEFNASICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHSEF +    + +MALLPL+TKFRGPAP +     +DIIDE+++ FK+ VFFKN+EI+S+ADRVL+YL LYI++ LK + +C N+ Q  KE+N++GIA F +PGDPGFP+EL+  Y KP+D  E + ++ Y+QQLRQE   R++E++FPG+ +E PSKWW+CFSK+KF+D+ L+ PG+
Sbjct:    3 AYHSEFVQPPKLVGNMALLPLRTKFRGPAPQEASLE-KDIIDEALFYFKANVFFKNYEIKSEADRVLIYLTLYILDVLKKVHRCQNKNQAAKEINAMGIAKFDIPGDPGFPRELNAMYAKPRDRAEDDAMRQYIQQLRQETGQRLLERLFPGNPNEKPSKWWICFSKRKFMDQTLTRPGQ 181
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. TrEMBL
Match: G4VSI1 (Actin-related protein 2/3 complex subunit 3 OS=Schistosoma mansoni OX=6183 GN=Smp_032310 PE=3 SV=1)

HSP 1 Score: 218.779 bits (556), Expect = 6.852e-69
Identity = 98/181 (54.14%), Postives = 138/181 (76.24%), Query Frame = 3 
Query:   75 AYHSEFTEFNASICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGRF 617
             +HSEF     +I +MALLPL+TKFRGPAP  MD   +DIIDE++YLFKSL+F + +E++S+ADRVL+YLVLYI+ECL+ LQ+C NR  G KEL ++ I+ F +PGDP FP+EL+N Y KPK+  E E ++ Y+ QLRQE+  R+++K++    S PPSKWW+CF K++F+D++L+  G F
Sbjct:    3 VHHSEFVPAPNTIGNMALLPLRTKFRGPAPMNMDLE-KDIIDEALYLFKSLIFLRQYELKSEADRVLVYLVLYILECLRKLQRCPNRTSGAKELAAMAISRFDIPGDPDFPRELNNMYAKPKNATEMETMRGYLTQLRQELGVRLLDKVYRNDNS-PPSKWWLCFGKRRFMDQSLTPLGVF 181
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Cavefish
Match: arpc3 (actin related protein 2/3 complex, subunit 3 [Source:ZFIN;Acc:ZDB-GENE-040625-107])

HSP 1 Score: 161.384 bits (407), Expect = 4.473e-50
Identity = 84/181 (46.41%), Postives = 118/181 (65.19%), Query Frame = 3 
Query:   75 AYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS   + +   + +MALLPLKT+F+GPAP +     QDIIDE+IY FK+ VFFKN+EI                       KCS++ QGEKE+ +LGI NF +PG+PGFP  L+  Y+KP +  E E ++AY+QQ+RQE   R+ E++F    ++ PSKWW+CF KK+F++K+LS PG+
Sbjct:    3 AYHSSLMDGDTKLVGNMALLPLKTQFKGPAPKETKD--QDIIDEAIYYFKANVFFKNYEI-----------------------KCSSKGQGEKEMYTLGITNFPIPGEPGFP--LNAMYVKPSNKQEEETMRAYLQQIRQETGLRLCERVF-DPQTDKPSKWWVCFVKKQFMNKSLSAPGQ 155
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Yeast
Match: ARC18 (Subunit of the ARP2/3 complex; ARP2/3 is required for the motility and integrity of cortical actin patches [Source:SGD;Acc:S000004362])

HSP 1 Score: 149.828 bits (377), Expect = 3.690e-46
Identity = 81/181 (44.75%), Postives = 123/181 (67.96%), Query Frame = 3 
Query:   75 AYHSEFT---EFNASICSMALLPLKTKFRGPA-PTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKP-KDINEREKLKAYMQQLRQEMSSRIIEKIFPGSAS-EPPSKWWMCFSKKKFLDKAL 599
            AYHS F      +  + + ALLPL TKFRGPA P+  D    DIIDE + LF++  FFKNFEI+S ADRVL+Y +L+I +CL  L+  ++  +  K L ++ + NF++PG PGFP  L+N Y  P +D N  + LK Y+QQ RQE++ R++E+++  + S E PSK+W+ F++++F++K+L
Sbjct:    3 AYHSTFPVDPNTDRMVGNFALLPLNTKFRGPAYPSNSDY---DIIDECLDLFRANSFFKNFEIKSPADRVLIYGILFINDCLAHLKITTSFNEAVKVLTNVALDNFTLPGTPGFP--LNNVYQVPVQDHNSMDLLKTYIQQFRQELAMRLLERVYSSTDSKEYPSKFWLAFTRRRFMNKSL 178
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Nematostella
Match: EDO39405 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SA67])

HSP 1 Score: 191.815 bits (486), Expect = 3.653e-62
Identity = 90/180 (50.00%), Postives = 132/180 (73.33%), Query Frame = 3 
Query:   75 AYHSEFTEFNASICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS  +    S+ +MALLPL + F+GPAP+     + DI+DE++Y FK+ VFFK++EI+S+ADRVL+YL LY+ ECLK LQ+  ++ Q +KE+ +L +ANF +PGD GFP  L+  Y KP +  E + ++AY+ QLRQE+  R++EK+F    ++ P+KWWMCF K+KF+DK+LS PG+
Sbjct:    3 AYHSSLSA-PLSVGNMALLPLNSSFKGPAPS--GDGSADIVDETLYYFKANVFFKSYEIKSEADRVLIYLTLYVSECLKKLQRIQSKEQAKKEMKTLAMANFHLPGDAGFP--LNAMYQKPANKQEADNMRAYLTQLRQELGQRLVEKVF-DPQTDKPTKWWMCFVKRKFMDKSLSAPGQ 176
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Medaka
Match: arpc3 (actin related protein 2/3 complex subunit 3 [Source:NCBI gene;Acc:101161909])

HSP 1 Score: 199.134 bits (505), Expect = 1.464e-64
Identity = 97/181 (53.59%), Postives = 134/181 (74.03%), Query Frame = 3 
Query:   75 AYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS   E N   I +MALLP+KT+F+GPA  + D    DIIDE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKCS+R QGEKE+ +LGI NF +PG+PGFP  L+  Y KP    + E ++AY+QQ+RQE   R+ +++F    ++ PSKWW+CF K++F++K+LS PG+
Sbjct:    3 AYHSNLMEPNTRMIGNMALLPIKTQFKGPA--RGDGVESDIIDEAIYYFKANVFFKNYEIKNEADRTLIYVTLYISECLKKLQKCSSRGQGEKEMYTLGITNFPIPGEPGFP--LNAMYAKPASKTDEETMRAYLQQIRQETGLRLCDRVF-DPQTDKPSKWWVCFVKRQFMNKSLSAPGQ 178
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Medaka
Match: arpc3 (actin related protein 2/3 complex subunit 3 [Source:NCBI gene;Acc:101161909])

HSP 1 Score: 196.823 bits (499), Expect = 1.282e-63
Identity = 96/181 (53.04%), Postives = 133/181 (73.48%), Query Frame = 3 
Query:   75 AYHSEFTEFNAS-ICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGR 614
            AYHS   E N   I +MALLP+KT+F+GPA      +  DIIDE+IY FK+ VFFKN+EI+++ADR L+Y+ LYI ECLK LQKCS+R QGEKE+ +LGI NF +PG+PGFP  L+  Y KP    + E ++AY+QQ+RQE   R+ +++F    ++ PSKWW+CF K++F++K+LS PG+
Sbjct:    6 AYHSNLMEPNTRMIGNMALLPIKTQFKGPA----RGDESDIIDEAIYYFKANVFFKNYEIKNEADRTLIYVTLYISECLKKLQKCSSRGQGEKEMYTLGITNFPIPGEPGFP--LNAMYAKPASKTDEETMRAYLQQIRQETGLRLCDRVF-DPQTDKPSKWWVCFVKRQFMNKSLSAPGQ 179
[Close]
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Planmine SMEST
Match: SMESG000003941.1 (SMESG000003941.1)

HSP 1 Score: 338.961 bits (868), Expect = 3.893e-120
Identity = 166/166 (100.00%), Postives = 166/166 (100.00%), Query Frame = 3 
Query:  120 MALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGRF 617
            MALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGRF
Sbjct:    1 MALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFKSLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGIANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKIFPGSASEPPSKWWMCFSKKKFLDKALSNPGRF 166
The following BLAST results are available for this feature:
BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ARPC33.783e-6351.93actin related protein 2/3 complex subunit 3 [Sourc... [more]
ARPC31.548e-2656.96actin related protein 2/3 complex subunit 3 [Sourc... [more]
ARPC35.518e-2652.22actin related protein 2/3 complex subunit 3 [Sourc... [more]
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BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
arx-51.367e-4441.85Probable actin-related protein 2/3 complex subunit... [more]
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BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Arpc3B2.205e-6251.96gene:FBgn0065032 transcript:FBtr0074410[more]
Arpc3A1.379e-5946.67gene:FBgn0038369 transcript:FBtr0300570[more]
Arpc3A1.379e-5946.67gene:FBgn0038369 transcript:FBtr0334594[more]
Arpc3B6.652e-5652.44gene:FBgn0065032 transcript:FBtr0113478[more]
Arpc3B6.652e-5652.44gene:FBgn0065032 transcript:FBtr0334462[more]
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BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
arpc32.138e-6453.04actin related protein 2/3 complex, subunit 3 [Sour... [more]
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BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
arpc38.208e-6451.37actin related protein 2/3 complex subunit 3 [Sourc... [more]
arpc31.116e-6351.93actin related protein 2/3 complex subunit 3 [Sourc... [more]
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BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Arpc36.574e-6453.04actin related protein 2/3 complex, subunit 3 [Sour... [more]
Arpc33.032e-6254.76actin related protein 2/3 complex, subunit 3 [Sour... [more]
Arpc34.721e-5456.34actin related protein 2/3 complex, subunit 3 [Sour... [more]
Arpc35.218e-5456.34actin related protein 2/3 complex, subunit 3 [Sour... [more]
Arpc38.093e-5154.79actin related protein 2/3 complex, subunit 3 [Sour... [more]
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BLAST of Actin-related protein 2/3 complex subunit 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q7T0U5|ARC3B_XENLA4.169e-6352.49Actin-related protein 2/3 complex subunit 3-B OS=X... [more]
sp|Q9JM76|ARPC3_MOUSE4.599e-6353.04Actin-related protein 2/3 complex subunit 3 OS=Mus... [more]
sp|O15145|ARPC3_HUMAN1.817e-6251.93Actin-related protein 2/3 complex subunit 3 OS=Hom... [more]
sp|Q3T035|ARPC3_BOVIN1.817e-6251.93Actin-related protein 2/3 complex subunit 3 OS=Bos... [more]
sp|A1DPK7|ARC3A_XENLA2.690e-6251.93Actin-related protein 2/3 complex subunit 3-A OS=X... [more]
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BLAST of Actin-related protein 2/3 complex subunit 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4S2M8922.662e-7256.42Actin-related protein 2/3 complex subunit 3 OS=Opi... [more]
A0A267ET163.073e-7254.05Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1I8GBR61.386e-7155.00Actin-related protein 2/3 complex subunit 3 OS=Mac... [more]
A0A1I8J5542.612e-7155.00Actin-related protein 2/3 complex subunit 3 OS=Mac... [more]
G4VSI16.852e-6954.14Actin-related protein 2/3 complex subunit 3 OS=Sch... [more]
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BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
arpc34.473e-5046.41actin related protein 2/3 complex, subunit 3 [Sour... [more]
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BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
ARC183.690e-4644.75Subunit of the ARP2/3 complex; ARP2/3 is required ... [more]
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BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO394053.653e-6250.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Actin-related protein 2/3 complex subunit 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
arpc31.464e-6453.59actin related protein 2/3 complex subunit 3 [Sourc... [more]
arpc31.282e-6353.04actin related protein 2/3 complex subunit 3 [Sourc... [more]
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BLAST of Actin-related protein 2/3 complex subunit 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000003941.13.893e-120100.00SMESG000003941.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002941 ID=SMED30002941|Name=Actin-related protein 2/3 complex subunit 3|organism=Schmidtea mediterranea sexual|type=transcript|length=696bp
GTGGTTTAATGTGATATAATTAATATTAAGACCATTTGAATTATCAATAG
TTTCCTGTATTTTTAATTTCAATGGCTTATCATTCTGAGTTTACGGAATT
TAATGCATCCATATGTAGTATGGCTTTATTACCATTAAAAACAAAATTTC
GAGGTCCTGCACCAACACAAATGGACCAAAATGCCCAAGACATTATTGAC
GAATCTATTTATTTATTTAAATCTCTAGTATTTTTTAAGAATTTTGAAAT
TCAATCAGATGCTGATCGAGTACTTATGTATCTCGTTCTTTACATTATAG
AATGTTTAAAGTTATTACAAAAGTGTAGTAATCGCTTGCAGGGAGAGAAG
GAACTTAATTCATTAGGCATTGCAAATTTCAGTATGCCTGGTGATCCTGG
TTTTCCTCAAGAACTTTCAAATTTTTATTTAAAACCCAAAGATATTAACG
AACGAGAAAAATTGAAAGCATACATGCAGCAATTACGTCAAGAAATGTCG
TCACGAATTATTGAAAAGATATTTCCAGGTTCAGCAAGTGAACCACCTAG
TAAATGGTGGATGTGCTTCTCGAAGAAGAAATTTCTCGACAAAGCTCTTA
GCAATCCAGGACGATTTTAAATTTCTAGTGACATCTTGATTTTGAAAATG
AAATTTTTTAATTAGTATAATGAAATATATTTTTTAATTTTTTAAA
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protein sequence of SMED30002941-orf-1

>SMED30002941-orf-1 ID=SMED30002941-orf-1|Name=SMED30002941-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=183bp
MAYHSEFTEFNASICSMALLPLKTKFRGPAPTQMDQNAQDIIDESIYLFK
SLVFFKNFEIQSDADRVLMYLVLYIIECLKLLQKCSNRLQGEKELNSLGI
ANFSMPGDPGFPQELSNFYLKPKDINEREKLKAYMQQLRQEMSSRIIEKI
FPGSASEPPSKWWMCFSKKKFLDKALSNPGRF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036753ARPC3_sf
IPR007204ARPC3
Vocabulary: cellular component
TermDefinition
GO:0005856cytoskeleton
GO:0005885Arp2/3 protein complex
GO:0005737cytoplasm
Vocabulary: biological process
TermDefinition
GO:0034314Arp2/3 complex-mediated actin nucleation
GO:0030833regulation of actin filament polymerization
Vocabulary: molecular function
TermDefinition
GO:0003779actin binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR007204Actin-related protein 2/3 complex subunit 3PIRSFPIRSF016315p21-ARCcoord: 1..176
e-value: 1.9E-68
score: 227.4
IPR007204Actin-related protein 2/3 complex subunit 3PFAMPF04062P21-Arccoord: 2..176
e-value: 7.7E-67
score: 224.7
IPR007204Actin-related protein 2/3 complex subunit 3PANTHERPTHR12391ARP2/3 COMPLEX 21 KD SUBUNITcoord: 2..180
IPR036753Actin-related protein 2/3 complex subunit 3 superfamilyGENE3DG3DSA:1.10.1760.10coord: 1..181
e-value: 2.9E-67
score: 227.9
IPR036753Actin-related protein 2/3 complex subunit 3 superfamilySUPERFAMILYSSF69060Arp2/3 complex 21 kDa subunit ARPC3coord: 2..176