Alpha-2-macroglobulin-like protein 1

Overview
NameAlpha-2-macroglobulin-like protein 1
Smed IDSMED30002925
Length (bp)5535
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Alpha-2-macroglobulin-like protein 1 (SMED30002925) t-SNE clustered cells

Violin plots show distribution of expression levels for Alpha-2-macroglobulin-like protein 1 (SMED30002925) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Alpha-2-macroglobulin-like protein 1 (SMED30002925) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Alpha-2-macroglobulin-like protein 1 (SMED30002925) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30002925

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
anterior pole progenitor cellSMED30002925SMESG000041500.1 SMED30002925smed_20140614PMID:29906446
Zeng et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle progenitor cellSMED30002925SMESG000041500.1 SMED30002925smed_20140614PMID:29906446
Zeng et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30002925SMESG000041500.1 dd_Smed_v4_12472_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30002925SMESG000041500.1 dd_Smed_v4_12472_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30002925SMESG000041500.1 dd_Smed_v4_12472_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30002925SMESG000041500.1 dd_Smed_v4_12472_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30002925SMESG000041500.1 Contig41384newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30002925SMESG000041500.1 Contig41384uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
pharynx musculatureSMED30002925SMESG000041500.1 dd_Smed_v4_12472_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Human
Match: DLL4 (delta like canonical Notch ligand 4 [Source:HGNC Symbol;Acc:HGNC:2910])

HSP 1 Score: 82.4185 bits (202), Expect = 5.904e-15
Identity = 40/107 (37.38%), Postives = 54/107 (50.47%), Query Frame = 3 
Query: 1917 VCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQT 2231
            +C  RND  GHYVC      +SC+  WTG  C  P C + C+  NG C +   C C+ GW G+ CN+C+    C +G C     C C  GW G  CD +  Y  + +
Sbjct:  187 LCKKRNDHFGHYVC-QPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHS 292
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Human
Match: JAG2 (jagged canonical Notch ligand 2 [Source:HGNC Symbol;Acc:HGNC:6189])

HSP 1 Score: 82.0333 bits (201), Expect = 1.058e-14
Identity = 42/105 (40.00%), Postives = 54/105 (51.43%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  RND  GHY CD    K +CM+ W G  C    CK  CN  +G C     C C YGW G++C++CV    C++G+CVE   C C   W G  CD +  Y  + 
Sbjct:  211 CRPRNDFFGHYTCDQYGNK-ACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSH 314
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Human
Match: JAG2 (jagged canonical Notch ligand 2 [Source:HGNC Symbol;Acc:HGNC:6189])

HSP 1 Score: 81.6481 bits (200), Expect = 1.302e-14
Identity = 42/105 (40.00%), Postives = 54/105 (51.43%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  RND  GHY CD    K +CM+ W G  C    CK  CN  +G C     C C YGW G++C++CV    C++G+CVE   C C   W G  CD +  Y  + 
Sbjct:  211 CRPRNDFFGHYTCDQYGNK-ACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSH 314
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Human
Match: JAG1 (jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188])

HSP 1 Score: 76.2554 bits (186), Expect = 6.358e-13
Identity = 44/121 (36.36%), Postives = 59/121 (48.76%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQ-NQTKLHRKLVKKSIPIK 2273
            C  R+D  GHY CD    K +CME W G  C    C+  C+  +G C     C C+YGW G YC+KC+    C++G C E   C+C   W G  CD +  Y   +Q  L+      + P K
Sbjct:  200 CRPRDDFFGHYACDQNGNK-TCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDK 319
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Human
Match: DLK1 (delta like non-canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:2907])

HSP 1 Score: 67.781 bits (164), Expect = 7.999e-13
Identity = 31/69 (44.93%), Postives = 39/69 (56.52%), Query Frame = 3 
Query: 2001 GNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCD 2201
            G++    +C   CN  NG C   N C C+ GW G  C++CVTS  CL+G C E   CIC+ GW G  CD
Sbjct:   18 GHSTYGAECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDGWDGELCD 86
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Celegans
Match: T01D3.1 (pep chromosome:WBcel235:V:13689892:13703330:1 gene:WBGene00011326.1 transcript:T01D3.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T01D3.1)

HSP 1 Score: 68.1662 bits (165), Expect = 6.740e-11
Identity = 34/90 (37.78%), Postives = 49/90 (54.44%), Query Frame = 3 
Query: 1944 GHYVCDNLTKKMSCMENWTGNNCLTPKCKADC-NNGICVQINHCFCKYGWTGKYCN--KCVTSKDCLNGACVEGNDCICSAGWIGSNCDI 2204
            G+ +C NL     C + W+G++C  P+C  +C  +G C+Q N C C  GW G+ C+   C+ S+ C +G C     C C  GW GS C I
Sbjct: 1145 GNGLC-NLLNICLCNDGWSGSDCSIPRCLTNCTGHGKCIQPNSCECDAGWMGETCSVTSCIDSQ-CTHGHCGTNGLCKCEDGWQGSRCQI 1232

HSP 2 Score: 58.9214 bits (141), Expect = 4.609e-8
Identity = 32/94 (34.04%), Postives = 43/94 (45.74%), Query Frame = 3 
Query: 1944 GHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSK------DCLNGACVE-GNDCICSAGWIGSNCDI 2204
            GH   + L K   C + W G+ C  P C +   NGIC +   C C   + G  C+KCV         DC +G C      C C+ GW+G  CD+
Sbjct: 1211 GHCGTNGLCK---CEDGWQGSRCQIPLCNSCSLNGICTRPGFCSCFEDYGGSDCSKCVGDSCEACDFDCNHGICEPLTKTCSCAKGWMGGACDV 1301

HSP 3 Score: 58.5362 bits (140), Expect = 6.840e-8
Identity = 28/77 (36.36%), Postives = 41/77 (53.25%), Query Frame = 3 
Query: 1983 CMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCN--KCVTSKDCLN-GACVEGNDCICSAGWIGSNCDI 2204
            C   +TG +C  P       NG+C  +N C C  GW+G  C+  +C+T  +C   G C++ N C C AGW+G  C +
Sbjct: 1126 CPHGYTGFDCSIPLFCNCSGNGLCNLLNICLCNDGWSGSDCSIPRCLT--NCTGHGKCIQPNSCECDAGWMGETCSV 1200
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Celegans
Match: apx-1 (Anterior pharynx in excess protein 1 [Source:UniProtKB/Swiss-Prot;Acc:P41990])

HSP 1 Score: 65.855 bits (159), Expect = 1.980e-10
Identity = 32/78 (41.03%), Postives = 41/78 (52.56%), Query Frame = 3 
Query: 1983 CMENWTGNNCLTPKCKADCNN-GICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEG--NDCICSAGWIGSNCDIE 2207
            C   W+G +C  P C   C+N G CV  N C C  G+ G  C +C+    C+NG CV    N C C  G+IG  CDI+
Sbjct:  163 CSAGWSGEDCSNPICAGGCSNRGRCVAPNQCSCADGFNGTRCEQCLPRAGCVNGDCVNETPNTCKCRDGFIGDRCDID 240
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Celegans
Match: ten-1 (Teneurin-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ6])

HSP 1 Score: 57.7658 bits (138), Expect = 9.923e-8
Identity = 27/77 (35.06%), Postives = 34/77 (44.16%), Query Frame = 3 
Query: 1983 CMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLN-GACVEGNDCICSAGWIGSNCDIEG 2210
            C   W   +C    C+  C NG C+    C C  GW G  C     +  C + G C     C CS+GW G NC I+G
Sbjct:  463 CESGWDSVDCSQQACQ--CVNGDCLDDGSCQCWKGWRGSNCTDKKCAIGCEDRGKCASDGSCKCSSGWNGENCAIDG 537
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Celegans
Match: ten-1 (Teneurin-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ6])

HSP 1 Score: 57.7658 bits (138), Expect = 9.992e-8
Identity = 27/77 (35.06%), Postives = 34/77 (44.16%), Query Frame = 3 
Query: 1983 CMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLN-GACVEGNDCICSAGWIGSNCDIEG 2210
            C   W   +C    C+  C NG C+    C C  GW G  C     +  C + G C     C CS+GW G NC I+G
Sbjct:  645 CESGWDSVDCSQQACQ--CVNGDCLDDGSCQCWKGWRGSNCTDKKCAIGCEDRGKCASDGSCKCSSGWNGENCAIDG 719
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Celegans
Match: ten-1 (Teneurin-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ6])

HSP 1 Score: 57.7658 bits (138), Expect = 1.118e-7
Identity = 27/77 (35.06%), Postives = 34/77 (44.16%), Query Frame = 3 
Query: 1983 CMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLN-GACVEGNDCICSAGWIGSNCDIEG 2210
            C   W   +C    C+  C NG C+    C C  GW G  C     +  C + G C     C CS+GW G NC I+G
Sbjct:  724 CESGWDSVDCSQQACQ--CVNGDCLDDGSCQCWKGWRGSNCTDKKCAIGCEDRGKCASDGSCKCSSGWNGENCAIDG 798
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Fly
Match: Dl (gene:FBgn0000463 transcript:FBtr0083739)

HSP 1 Score: 81.2629 bits (199), Expect = 7.659e-15
Identity = 39/103 (37.86%), Postives = 55/103 (53.40%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  R+D  GH  C   T ++ C+  W G+ C  PKC   C +G C + N C C+ GW G  CN+CV   +C++G C +   CIC+ GW G  C+ +  Y  N 
Sbjct:  197 CRPRDDSFGHSTCSE-TGEIICLTGWQGDYCHIPKCAKGCEHGHCDKPNQCVCQLGWKGALCNECVLEPNCIHGTCNKPWTCICNEGWGGLYCNQDLNYCTNH 298
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Fly
Match: Dl (gene:FBgn0000463 transcript:FBtr0083740)

HSP 1 Score: 81.2629 bits (199), Expect = 7.659e-15
Identity = 39/103 (37.86%), Postives = 55/103 (53.40%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  R+D  GH  C   T ++ C+  W G+ C  PKC   C +G C + N C C+ GW G  CN+CV   +C++G C +   CIC+ GW G  C+ +  Y  N 
Sbjct:  197 CRPRDDSFGHSTCSE-TGEIICLTGWQGDYCHIPKCAKGCEHGHCDKPNQCVCQLGWKGALCNECVLEPNCIHGTCNKPWTCICNEGWGGLYCNQDLNYCTNH 298
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Fly
Match: Dl (gene:FBgn0000463 transcript:FBtr0304658)

HSP 1 Score: 81.2629 bits (199), Expect = 7.659e-15
Identity = 39/103 (37.86%), Postives = 55/103 (53.40%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  R+D  GH  C   T ++ C+  W G+ C  PKC   C +G C + N C C+ GW G  CN+CV   +C++G C +   CIC+ GW G  C+ +  Y  N 
Sbjct:  197 CRPRDDSFGHSTCSE-TGEIICLTGWQGDYCHIPKCAKGCEHGHCDKPNQCVCQLGWKGALCNECVLEPNCIHGTCNKPWTCICNEGWGGLYCNQDLNYCTNH 298
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Fly
Match: Ser (gene:FBgn0004197 transcript:FBtr0344121)

HSP 1 Score: 73.559 bits (179), Expect = 1.975e-12
Identity = 37/99 (37.37%), Postives = 52/99 (52.53%), Query Frame = 3 
Query: 1914 TVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGAC-VEGNDCICSAGWIGSNCD 2201
            T C  R+D+ GHY C +  +K+ C+  W G NC    CKA C+  +G C +   C C+ GW G  CN+C+    C +G+C      C+C   W G  CD
Sbjct:  251 TFCRPRDDQFGHYACGSEGQKL-CLNGWQGVNCEEAICKAGCDPVHGKCDRPGECECRPGWRGPLCNECMVYPGCKHGSCNGSAWKCVCDTNWGGILCD 348
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Fly
Match: Ser (gene:FBgn0004197 transcript:FBtr0085128)

HSP 1 Score: 73.559 bits (179), Expect = 1.975e-12
Identity = 37/99 (37.37%), Postives = 52/99 (52.53%), Query Frame = 3 
Query: 1914 TVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGAC-VEGNDCICSAGWIGSNCD 2201
            T C  R+D+ GHY C +  +K+ C+  W G NC    CKA C+  +G C +   C C+ GW G  CN+C+    C +G+C      C+C   W G  CD
Sbjct:  251 TFCRPRDDQFGHYACGSEGQKL-CLNGWQGVNCEEAICKAGCDPVHGKCDRPGECECRPGWRGPLCNECMVYPGCKHGSCNGSAWKCVCDTNWGGILCD 348
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Zebrafish
Match: jag1b (jagged canonical Notch ligand 1b [Source:NCBI gene;Acc:140423])

HSP 1 Score: 83.1889 bits (204), Expect = 2.516e-15
Identity = 42/102 (41.18%), Postives = 56/102 (54.90%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYL 2219
            C  R++  GHY CD    K +C+E WTG +C T  C+  C+  +G C Q   C C YGW G YC+KC+    C++G CVE   C+C   W G  CD +  Y 
Sbjct:  197 CRPRDEFFGHYTCDQNGNK-TCLEGWTGPDCNTAICRQGCSTEHGSCKQPGGCKCLYGWQGPYCDKCIPHPGCVHGTCVEPWQCLCDTNWGGQLCDKDLNYC 297
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Zebrafish
Match: jag1a (jagged canonical Notch ligand 1a [Source:NCBI gene;Acc:140421])

HSP 1 Score: 80.4925 bits (197), Expect = 2.072e-14
Identity = 39/96 (40.62%), Postives = 54/96 (56.25%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCD 2201
            C  R+D  GHY CD+   K +C+E W G  C T  CK  C+  +G C    +C C YGW G+YC++C+    C++G C+E   C+C   W G  CD
Sbjct:  201 CRPRDDFFGHYTCDHNGNK-TCLEGWAGPECNTAICKQGCSIEHGSCKVPGNCRCLYGWQGEYCDQCIPHPGCVHGTCIEPWQCLCDTNWGGQLCD 295
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Zebrafish
Match: jag1a (jagged canonical Notch ligand 1a [Source:NCBI gene;Acc:140421])

HSP 1 Score: 80.4925 bits (197), Expect = 2.100e-14
Identity = 39/96 (40.62%), Postives = 54/96 (56.25%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCD 2201
            C  R+D  GHY CD+   K +C+E W G  C T  CK  C+  +G C    +C C YGW G+YC++C+    C++G C+E   C+C   W G  CD
Sbjct:  201 CRPRDDFFGHYTCDHNGNK-TCLEGWAGPECNTAICKQGCSIEHGSCKVPGNCRCLYGWQGEYCDQCIPHPGCVHGTCIEPWQCLCDTNWGGQLCD 295
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Zebrafish
Match: dlb (deltaB [Source:NCBI gene;Acc:30141])

HSP 1 Score: 77.7962 bits (190), Expect = 7.237e-14
Identity = 40/105 (38.10%), Postives = 54/105 (51.43%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  R+D LGHY CD    K  C+  W G+ C  P C +DC+  +G C     C C+ GW G  C++CV    CL+G C +   C+C  GW G  C+ +  Y  N 
Sbjct:  174 CRPRDDTLGHYTCDENGNK-ECLVGWQGDYCSDPICSSDCSERHGYCESPGECKCRLGWQGPSCSECVHYPGCLHGTCSQPWQCVCKEGWGGLFCNQDLNYCTNH 277
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Zebrafish
Match: dll4 (delta-like 4 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-041014-73])

HSP 1 Score: 76.2554 bits (186), Expect = 2.391e-13
Identity = 38/96 (39.58%), Postives = 48/96 (50.00%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCD 2201
            C  R+D  GHY C N   ++SC+  W G  C  P C   C+  NG C +   C C+ GW GK+C +C T   C +G C     C C  GW G  CD
Sbjct:  181 CTPRDDRFGHYTC-NPDGQLSCLPGWKGEYCEEPICLEGCSEANGNCSKPGECVCREGWQGKFCTECKTYPACKHGTCHLPGQCNCKEGWGGLFCD 275
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Xenopus
Match: DLL4 (delta-like 4 [Source:NCBI gene;Acc:100489166])

HSP 1 Score: 80.8777 bits (198), Expect = 1.406e-14
Identity = 38/102 (37.25%), Postives = 55/102 (53.92%), Query Frame = 3 
Query: 1917 VCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTY 2216
            +C  R+D  GHY+C+    ++SC++ W G  C  P C   C+  NG C +   C C+ GW G++CN+C+    C +G C     CIC  GW G  CD +  Y
Sbjct:  178 LCKPRDDRFGHYICE-PDGRVSCLKGWKGEYCAEPICLDGCSEQNGYCNKPGECTCRPGWQGRFCNECIPHNGCRHGTCQIQWQCICDEGWGGLFCDQDLNY 278
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Xenopus
Match: DLL4 (delta-like 4 [Source:NCBI gene;Acc:100489166])

HSP 1 Score: 80.4925 bits (197), Expect = 1.627e-14
Identity = 38/102 (37.25%), Postives = 55/102 (53.92%), Query Frame = 3 
Query: 1917 VCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTY 2216
            +C  R+D  GHY+C+    ++SC++ W G  C  P C   C+  NG C +   C C+ GW G++CN+C+    C +G C     CIC  GW G  CD +  Y
Sbjct:  171 LCKPRDDRFGHYICE-PDGRVSCLKGWKGEYCAEPICLDGCSEQNGYCNKPGECTCRPGWQGRFCNECIPHNGCRHGTCQIQWQCICDEGWGGLFCDQDLNY 271
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Xenopus
Match: DLL4 (delta-like 4 [Source:NCBI gene;Acc:100489166])

HSP 1 Score: 80.4925 bits (197), Expect = 1.741e-14
Identity = 38/102 (37.25%), Postives = 55/102 (53.92%), Query Frame = 3 
Query: 1917 VCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTY 2216
            +C  R+D  GHY+C+    ++SC++ W G  C  P C   C+  NG C +   C C+ GW G++CN+C+    C +G C     CIC  GW G  CD +  Y
Sbjct:  165 LCKPRDDRFGHYICE-PDGRVSCLKGWKGEYCAEPICLDGCSEQNGYCNKPGECTCRPGWQGRFCNECIPHNGCRHGTCQIQWQCICDEGWGGLFCDQDLNY 265
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Xenopus
Match: DLL4 (delta-like 4 [Source:NCBI gene;Acc:100489166])

HSP 1 Score: 80.1073 bits (196), Expect = 2.459e-14
Identity = 38/102 (37.25%), Postives = 55/102 (53.92%), Query Frame = 3 
Query: 1917 VCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTY 2216
            +C  R+D  GHY+C+    ++SC++ W G  C  P C   C+  NG C +   C C+ GW G++CN+C+    C +G C     CIC  GW G  CD +  Y
Sbjct:  171 LCKPRDDRFGHYICE-PDGRVSCLKGWKGEYCAEPICLDGCSEQNGYCNKPGECTCRPGWQGRFCNECIPHNGCRHGTCQIQWQCICDEGWGGLFCDQDLNY 271
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Xenopus
Match: JAG2 (jagged 2 [Source:NCBI gene;Acc:100497180])

HSP 1 Score: 80.4925 bits (197), Expect = 2.482e-14
Identity = 51/138 (36.96%), Postives = 67/138 (48.55%), Query Frame = 3 
Query: 1836 EDLMILLVGNGQI------IKSKYIKN--SRLPKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYL 2219
            ED   LL   G +      I+ K  +N    +    C  RND +GHY CD+  KK +CME W G  C    CK  C+  +G C     C C YGW G YC++CV    C++G+C E  DC C   W G  C+ +  Y 
Sbjct:  128 EDQWTLLPLTGHVAQFDVKIRVKCDENYYGSMCNKFCRPRNDFVGHYTCDSNGKK-ACMEGWMGAECKQAICKQGCDLLHGGCTVPGECKCHYGWQGLYCSECVPYPGCVHGSCQEPWDCKCETNWGGLLCNKDLNYC 264
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Mouse
Match: Jag2 (jagged 2 [Source:MGI Symbol;Acc:MGI:1098270])

HSP 1 Score: 82.4185 bits (202), Expect = 5.088e-15
Identity = 43/105 (40.95%), Postives = 54/105 (51.43%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  RND  GHY CD    K +CM+ W G  C    CK  CN  +G C     C C YGW GK+C++CV    C++G+CVE   C C   W G  CD +  Y  + 
Sbjct:  211 CRPRNDFFGHYTCDQYGNK-ACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGKFCDECVPYPGCVHGSCVEPWHCDCETNWGGLLCDKDLNYCGSH 314
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Mouse
Match: Jag1 (jagged 1 [Source:MGI Symbol;Acc:MGI:1095416])

HSP 1 Score: 80.1073 bits (196), Expect = 2.427e-14
Identity = 45/121 (37.19%), Postives = 61/121 (50.41%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQ-NQTKLHRKLVKKSIPIK 2273
            C  R+D  GHY CD    K +CME W G +C    C+  C+  +G C     C C+YGW G YC+KC+    C++G C E   C+C   W G  CD +  Y   +Q  L+R     + P K
Sbjct:  200 CRPRDDFFGHYACDQNGNK-TCMEGWMGPDCNKAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGTCNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNRGTCSNTGPDK 319
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Mouse
Match: Dll4 (delta like canonical Notch ligand 4 [Source:MGI Symbol;Acc:MGI:1859388])

HSP 1 Score: 77.0258 bits (188), Expect = 1.551e-13
Identity = 38/107 (35.51%), Postives = 54/107 (50.47%), Query Frame = 3 
Query: 1917 VCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQT 2231
            +C  R+D  GHY C      +SC+  WTG  C  P C + C+  NG C + + C C+ GW G+ CN+C+    C +G C     C C  GW G  CD +  Y  + +
Sbjct:  188 LCKKRDDHFGHYECQ-PDGSLSCLPGWTGKYCDQPICLSGCHEQNGYCSKPDECICRPGWQGRLCNECIPHNGCRHGTCSIPWQCACDEGWGGLFCDQDLNYCTHHS 293
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Mouse
Match: Dll1 (delta like canonical Notch ligand 1 [Source:MGI Symbol;Acc:MGI:104659])

HSP 1 Score: 76.2554 bits (186), Expect = 3.099e-13
Identity = 36/101 (35.64%), Postives = 52/101 (51.49%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNN--GICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTY 2216
            C  R+D  GH+ C +  +KM C   W G  C  P C   C++  G C +   C C+ GW G+YC++C+    CL+G C +   C C  GW G  C+ +  Y
Sbjct:  191 CRPRDDAFGHFTCGDRGEKM-CDPGWKGQYCTDPICLPGCDDQHGYCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNY 290
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Mouse
Match: Tenm3 (teneurin transmembrane protein 3 [Source:MGI Symbol;Acc:MGI:1345183])

HSP 1 Score: 71.633 bits (174), Expect = 1.182e-11
Identity = 39/107 (36.45%), Postives = 56/107 (52.34%), Query Frame = 3 
Query: 1896 NSRLPKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADC-NNGICVQINHCFCKYGWTGKYCNKCVTSKDCL-NGACVEGNDCICSAGWIGSNCDIEG 2210
            N  + KT+C  +    G Y+ +  +   +C  NWTG +C    C  DC ++G+C+    C C+ GWTG  CN+      C  +G C +G  C CS GW G +C IEG
Sbjct:  640 NCEILKTMCADQCSGHGTYLQE--SGSCTCDPNWTGPDCSNEICSVDCGSHGVCMG-GSCRCEEGWTGPACNQRACHPRCAEHGTCKDGK-CECSQGWNGEHCTIEG 742

HSP 2 Score: 56.6102 bits (135), Expect = 4.506e-7
Identity = 33/106 (31.13%), Postives = 49/106 (46.23%), Query Frame = 3 
Query: 1983 CMENWTGN-------NCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLN------GACVEGNDCICSAGWIGSNCDIEGTYLQNQTKLHRKLVKKS 2261
            C   W G         C+ P+C      GIC+ +  C C  G+ G+ C +     DCL+      G C+ G +C C+ GW GSNC+I  T   +Q   H   +++S
Sbjct:  566 CFSGWKGTECDVPTTQCIDPQCGG---RGICI-MGSCACNSGYKGENCEEA----DCLDPGCSNHGVCIHG-ECHCNPGWGGSNCEILKTMCADQCSGHGTYLQES 662
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. UniProt/SwissProt
Match: sp|Q90Y54|JAG1B_DANRE (Protein jagged-1b OS=Danio rerio OX=7955 GN=jag1b PE=2 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.775e-14
Identity = 42/102 (41.18%), Postives = 56/102 (54.90%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYL 2219
            C  R++  GHY CD    K +C+E WTG +C T  C+  C+  +G C Q   C C YGW G YC+KC+    C++G CVE   C+C   W G  CD +  Y 
Sbjct:  197 CRPRDEFFGHYTCDQNGNK-TCLEGWTGPDCNTAICRQGCSTEHGSCKQPGGCKCLYGWQGPYCDKCIPHPGCVHGTCVEPWQCLCDTNWGGQLCDKDLNYC 297
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. UniProt/SwissProt
Match: sp|Q9NR61|DLL4_HUMAN (Delta-like protein 4 OS=Homo sapiens OX=9606 GN=DLL4 PE=1 SV=1)

HSP 1 Score: 82.4185 bits (202), Expect = 2.835e-14
Identity = 40/107 (37.38%), Postives = 54/107 (50.47%), Query Frame = 3 
Query: 1917 VCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQT 2231
            +C  RND  GHYVC      +SC+  WTG  C  P C + C+  NG C +   C C+ GW G+ CN+C+    C +G C     C C  GW G  CD +  Y  + +
Sbjct:  187 LCKKRNDHFGHYVC-QPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHS 292
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. UniProt/SwissProt
Match: sp|Q9QYE5|JAG2_MOUSE (Protein jagged-2 OS=Mus musculus OX=10090 GN=Jag2 PE=2 SV=2)

HSP 1 Score: 82.4185 bits (202), Expect = 3.650e-14
Identity = 43/105 (40.95%), Postives = 54/105 (51.43%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  RND  GHY CD    K +CM+ W G  C    CK  CN  +G C     C C YGW GK+C++CV    C++G+CVE   C C   W G  CD +  Y  + 
Sbjct:  211 CRPRNDFFGHYTCDQYGNK-ACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGKFCDECVPYPGCVHGSCVEPWHCDCETNWGGLLCDKDLNYCGSH 314
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. UniProt/SwissProt
Match: sp|P97607|JAG2_RAT (Protein jagged-2 (Fragment) OS=Rattus norvegicus OX=10116 GN=Jag2 PE=2 SV=1)

HSP 1 Score: 82.4185 bits (202), Expect = 3.947e-14
Identity = 43/105 (40.95%), Postives = 54/105 (51.43%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  RND  GHY CD    K +CM+ W G  C    CK  CN  +G C     C C YGW GK+C++CV    C++G+CVE   C C   W G  CD +  Y  + 
Sbjct:  165 CRPRNDFFGHYTCDQYGNK-ACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGKFCDECVPYPGCVHGSCVEPWHCDCETNWGGLLCDKDLNYCGSH 268
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. UniProt/SwissProt
Match: sp|Q9Y219|JAG2_HUMAN (Protein jagged-2 OS=Homo sapiens OX=9606 GN=JAG2 PE=1 SV=3)

HSP 1 Score: 81.6481 bits (200), Expect = 5.892e-14
Identity = 42/105 (40.00%), Postives = 54/105 (51.43%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  RND  GHY CD    K +CM+ W G  C    CK  CN  +G C     C C YGW G++C++CV    C++G+CVE   C C   W G  CD +  Y  + 
Sbjct:  211 CRPRNDFFGHYTCDQYGNK-ACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSH 314
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. TrEMBL
Match: A0A4Y6HTR9 (Alpha-2-macroglobulin OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 186.037 bits (471), Expect = 3.141e-43
Identity = 139/524 (26.53%), Postives = 259/524 (49.43%), Query Frame = 3 
Query:  810 KLKPKSEILKLT-LSDTNNITIKSWSKNSQDKSFNVEYILPKDSVSGTWKIAYQLSNTNQQDFHEFELRSEDEKPVNAKMNISIKYNGDITIMTRNIQFFVCAEYSKFRSVKGKLSGTICLKYPEEELTTERPCLMFESYMNGSSKCVWIETSTDGLQLKNISYSQRLSRL--IISVDIIDEYSKKNHLYHYMGPTLKNSKYKISFLSSPYFKSMLPYYGRIQTLQHNDKPFSNASIVIQCNTVNFPYNWGHYSKHVSDKDGNIYFILSSPPVNLEIITCDIEDLSFTEEKSIHVRYYRSSITQTLERSKSSKKKNIQLKLLDRKMXXXXXXXXXXXXQSNNVVTE-DLMILLVGNGQIIKSKYIKNSRLPKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQTKLHRKLVKKSIPIKEIKTTEINLIFTAIINLK-IPSMMSAVTVIVH 2366
            K K  S+I +L  + +     +  W   S  K+ ++ Y L  D V GTWK   + +   Q++  +FE++    + V  +  +++    +I    ++I F VC++YS  +++K ++ GT C+ + ++     R C  F+S +   S C  I+  T  +   N+    R +R   +I+V +I+  +         G  +  + + I F+S  Y+K  LPY+G+++ ++HN+KP SN ++ I      +   WG +  + S+K+G + FI+ + P+  + +T  + ++S      I      +++ Q++   +S  K  +Q   L+ K+   ++  + +   +N  ++E ++ + +   G+I  +  I+   +P   C  RND  GHY C N T  + C+  W G NC  P C   C NG CV+ N C CK  W G+ C++C+ +  C NG C  GNDC C  GW   +C  +G  + +    +  ++  S+   EIK  E   +F  II +  + +M   V +I++
Sbjct:  204 KDKNMSQIFELIFIENPTGARVAQWINVSLAKAMDLRYQLTNDPVFGTWK--SKATFDGQEELIQFEVK----RYVLPRFVVTVNPPKEILANQKSIGFKVCSKYSTGKTMKAQIHGTFCMHHTDKT----RNCEYFKSTLLKQS-CNRIDIDTKSIF--NLKSKSRFTRTKSVINVTVIENGTSSVVSKVVEGSGIMYTSFAIKFVSKLYYKPGLPYFGQLKLVRHNNKPASNINVSIDLENWAYGQGWGFHRIYTSNKEGIVDFIVPNIPLE-QSVTVRVNEVS----NDIKAPMSAATLYQSIANWESVDKYYMQFLPLNSKVKCPDDLNLTIV--TNYDISEINMYVQIFSRGRI--TDMIEYPSIP-VKCFPRNDFFGHYECVNGTV-LVCLPGWKGGNCREPICVGGCLNGACVEPNKCICKAYWKGENCDQCIIAPYCKNGYCKNGNDCKCYPGWQSFDCSKKGPKVHSYEN-YSTIMPTSVKQTEIKKFEKQTVFERIITVPLLKNMGPDVHIIIY 702
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. TrEMBL
Match: A0A0V0J5K4 (Alpha-1-inhibitor 3 (Fragment) OS=Schistocephalus solidus OX=70667 GN=A1I3 PE=4 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 1.635e-25
Identity = 124/524 (23.66%), Postives = 214/524 (40.84%), Query Frame = 3 
Query:  846 LSDTNNITIKSWSKNSQDKSFNVEYILPKDSVSGTWKIAYQLSNTNQQDFHEFELRSEDEKPVNAKMNISIKYNGDITIMTRNIQFFVCAEYSKFRSVKGKLSGTICLKYPEEELTTER---------PCLMFESYMNGSSKCVWIETSTDGLQ------LKNISYSQRL------------SRLIISVDIIDEYSK-----KNHLYHYMGPTLKNSKYKISFLSSPYFKSMLPYYGRIQTLQHN---DKPFSNASI-VIQCNTVNFPY-------NWGHYSKHVS-DKDGNIYFILSSPP--------VNLEIITCDIEDLSFTEEKSIHVRYYRSSI------------TQTLERSKSSKKKNIQLKLLDRKMXXXXXXXXXXXXQSNN-VVTEDLMILLVGNGQIIKSKYIKNSRLPKTVCHTRNDELGHYVCDNLTK-----KMSCMENWTGNNCLTPKC-KADCN-NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCD 2201
            + D +   +K W   SQ  +FN+ + L  D+  G W++   +  ++Q       L  + +  V  +   SI+   ++ I     +F VCA Y+   S +G     IC+   E+ L  ++          CL          +C+ +  S  G          N++    L            +  I++V   D  S      + ++ H+  P       K+S      ++  LP YG+++  +       P    +I VI+ +    P+       N   Y K V  + DG  +F+L  PP        VN++II  ++     T   S  +++                  ++L R KS  K  ++++ ++    +     I L + +N  +  + L +  V  G   +   +        VC   + +LGH+ C+   K     ++SC+  WTG NCLTP C +  C   G+CV    C CK GWTG+ C  CV  + CL G CV+G+DC+C AG+ G  C+
Sbjct:  279 IEDPSGNRVKEWKNVSQTTAFNLSFPLLPDASEGAWRLVANVFTSSQT------LEVDVKNYVLPRFLASIQVPAEVDINAETTRFNVCATYTNGNSFQGHYDAQICI-CSEQTLRQQQNLGTPFDNNMCLSESDAKTPGGRCIRVAGSLSGTPENAGCVTANVTVKSLLNDVQGRYGWGHQAGFIVTVSEADTGSAVTQFGQANIRHFQAP-------KLSLEIDSSYRPGLPIYGKVRLTEMRTVTRGPSVTVNITVIEIHNPCGPWFREGNILNPNVYFKQVMLNSDGIAFFVL--PPIKSVKDLEVNVDIIRDELTVTPTTTTSSPFLQHRMGPFWAPTLKDANFHTFESLRRWKSLGKLALKIRSINGNSPVTCPGRINLSIMANAPMAGKTLFLEYVSRGVPTQRSAVLQPASSGYVCADEDSDLGHFTCNAGFKPGDVGEISCLAGWTGENCLTPHCSETQCGKGGLCVAPGRCVCKKGWTGERCENCVPRQGCLRGRCVQGDDCVCEAGYTGYLCN 786
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. TrEMBL
Match: A0A183SB52 (Alpha-1-inhibitor 3 OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS1450 PE=4 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 3.875e-25
Identity = 122/524 (23.28%), Postives = 213/524 (40.65%), Query Frame = 3 
Query:  846 LSDTNNITIKSWSKNSQDKSFNVEYILPKDSVSGTWKIAYQLSNTNQQDFHEFELRSEDEKPVNAKMNISIKYNGDITIMTRNIQFFVCAEYSKFRSVKGKLSGTICLKYPEEELTTER---------PCLMFESYMNGSSKCVWIETSTDGLQ------LKNISYSQRL------------SRLIISVDIIDEYSK-----KNHLYHYMGPTLKNSKYKISFLSSPYFKSMLPYYGRIQ-----TLQHNDKPFSNASIVIQCNTVNFPYNWGH------YSKHVS-DKDGNIYFILSSPP--------VNLEIITCDIEDLSFTEEKSIHVRYYRSSI------------TQTLERSKSSKKKNIQLKLLDRKMXXXXXXXXXXXXQSNN-VVTEDLMILLVGNGQIIKSKYIKNSRLPKTVCHTRNDELGHYVCDNLTK-----KMSCMENWTGNNCLTPKC-KADCN-NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCD 2201
            + D +   +K W    Q  +FN+ + L  D+  G W++   +  ++Q       L  + +  V  +   SI+   ++ I     +F VCA Y+   S +G     IC+   E+ L  ++          CL          +C+ +  S  G          N++    L            +  I++V   D  S      + ++ H+  P       K+S      ++  LP YG+++     T+        N +++   N     +  G+      Y K V  + DG  +F+L  PP        VN++II  ++     T   S  +++                  ++L R KS  K  ++++ ++    +     I L + +N  +  + L +  V  G   +   +        VC   + +LGH+ C+   K     ++SC+  WTG NCLTP C +  C   G+CV    C CK GWTG+ C  CV  + CL+G CV+G+DCIC AG+ G  C+
Sbjct:  279 IEDPSGNRVKEWKNVPQTTAFNLSFPLLPDASEGAWRLVANVFTSSQT------LEVDVKNYVLPRFLASIQVPAEVDINAETTRFNVCATYTNGNSFQGHYDAQICI-CSEQTLRQQQNLGTPFDNNMCLSESDAKTPGGRCIRVAGSLSGTPENAGCVTANVTVKSLLNDVQGRYGWGHQAGFIVTVSEADTGSAVTQFGQANIRHFQAP-------KLSLEIDSSYRPGLPIYGKVRLTEMRTVTRGPSVTVNITVIEIHNPCGPWFREGNILNPNVYFKQVMLNSDGIAFFVL--PPIKSVKDLEVNVDIIRDELTVTPTTTTSSPFLQHRMGPFWAPPLKDANFHTFESLRRWKSLGKLALKIRSINGNSPVTCPGRINLSIMANAPMAGKTLFLEYVSRGVPTQRSAVLQPASSGYVCADEDSDLGHFTCNAGFKPGDVGEISCLAGWTGENCLTPHCSETQCGKGGLCVAPGRCVCKKGWTGERCENCVPRQGCLHGRCVQGDDCICEAGYTGYLCN 786
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. TrEMBL
Match: A0A0X3Q5K4 (Uncharacterized protein (Fragment) OS=Schistocephalus solidus OX=70667 GN=TR136897 PE=4 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 7.953e-25
Identity = 123/524 (23.47%), Postives = 213/524 (40.65%), Query Frame = 3 
Query:  846 LSDTNNITIKSWSKNSQDKSFNVEYILPKDSVSGTWKIAYQLSNTNQQDFHEFELRSEDEKPVNAKMNISIKYNGDITIMTRNIQFFVCAEYSKFRSVKGKLSGTICLKYPEEELTTER---------PCLMFESYMNGSSKCVWIETSTDGLQ------LKNISYSQRL------------SRLIISVDIIDEYSK-----KNHLYHYMGPTLKNSKYKISFLSSPYFKSMLPYYGRIQTLQHN---DKPFSNASI-VIQCNTVNFPY-------NWGHYSKHVS-DKDGNIYFILSSPP--------VNLEIITCDIEDLSFTEEKSIHVRYYRSSI------------TQTLERSKSSKKKNIQLKLLDRKMXXXXXXXXXXXXQSNN-VVTEDLMILLVGNGQIIKSKYIKNSRLPKTVCHTRNDELGHYVCDNLTK-----KMSCMENWTGNNCLTPKC-KADCN-NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCD 2201
            + D +   +K W    Q  +FN+ + L  D+  G W++   +  ++Q       L  + +  V  +   SI+   ++ I     +F VCA Y+   S +G     IC+   E+ L  ++          CL          +C+ +  S  G          N++    L            +  I++V   D  S      + ++ H+  P       K+S      ++  LP YG+++  +       P    +I VI+ +    P+       N   Y K V  + DG  +F+L  PP        VN++II  ++     T   S  +++                  ++L R KS  K  ++++ ++    +     I L + +N  +  + L +  V  G   +   +        VC   + +LGH+ C+   K     ++SC+  WTG NCLTP C +  C   G+CV    C CK GWTG+ C  CV  + CL G CV+G+DC+C AG+ G  C+
Sbjct:  279 IEDPSGNRVKEWKNVPQTTAFNLSFPLLPDASEGAWRLVANVFTSSQT------LEVDVKNYVLPRFLASIQVPAEVDINAETTRFNVCATYTNGNSFQGHYDAQICI-CSEQTLRQQQNLGTPFDNNMCLSESDAKTPGGRCIRVAGSLSGTPENAGCVTANVTVKSLLNDVQGRYGWGHQAGFIVTVSEADTGSAVTQFGQANIRHFQAP-------KLSLEIDSSYRPGLPIYGKVRLTEMRTVTRGPSVTVNITVIEIHNPCGPWFREGNILNPNVYFKQVMLNSDGIAFFVL--PPIKSVKDLEVNVDIIRDELTVTPTTTTSSPFLQHRMGPFWAPTLKDANFHTFESLRRWKSLGKLALKIRSINGNSPVTCPGRINLSIMANAPMAGKTLFLEYVSRGVPTQRSAVLQPASSGYVCADEDSDLGHFTCNAGFKPGDVGEISCLAGWTGENCLTPHCSETQCGKGGLCVAPGRCVCKKGWTGERCENCVPRQGCLRGRCVQGDDCVCEAGYTGYLCN 786
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. TrEMBL
Match: A0A430PYA3 (Alpha-2-macroglobulin OS=Schistosoma bovis OX=6184 GN=DC041_0007876 PE=4 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 4.258e-22
Identity = 47/97 (48.45%), Postives = 63/97 (64.95%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNL-TKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCD 2201
            C  R+DELGHY C +  + ++ C+  WTG NCL P C  +CN   G C + N C CK GWTG  CN+C+  ++CL+G C+ GNDC+C +GW G  CD
Sbjct:  678 CINRDDELGHYNCLSWNSTEIQCLPGWTGENCLIPICSIECNKNGGFCSKPNQCQCKSGWTGITCNQCIKRENCLHGKCLLGNDCVCDSGWTGYLCD 774
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Cavefish
Match: dlb (deltaB [Source:NCBI gene;Acc:30141])

HSP 1 Score: 83.1889 bits (204), Expect = 1.395e-15
Identity = 42/105 (40.00%), Postives = 55/105 (52.38%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  R+D LGHY CD    K  C+E W G+ C  P C ADC+  +G C     C C+ GW G  C++CV    CL+G C +   C+C  GW G  C+ +  Y  N 
Sbjct:  169 CRPRDDTLGHYNCDENGNK-ECLEGWQGDYCSDPICSADCSERHGYCESPGECKCRLGWQGPSCSECVRHPGCLHGTCTQPWQCVCKEGWGGLFCNQDLNYCTNH 272
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Cavefish
Match: jag1b (jagged canonical Notch ligand 1 [Source:NCBI gene;Acc:103034980])

HSP 1 Score: 78.5666 bits (192), Expect = 5.883e-14
Identity = 43/105 (40.95%), Postives = 56/105 (53.33%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIE----GTY 2216
            C  R++  GHY CD    K +C+E WTG  C T  C+  C+  +G C     C C YGW G YC+KC+    C++G CVE   C+C   W G  CD +    GTY
Sbjct:  202 CRPRDEFFGHYTCDQNGNK-TCLEGWTGPECNTAICRQGCSVEHGSCKLPGDCNCLYGWQGLYCDKCIPHPGCVHGTCVEPWQCLCDINWGGQLCDKDLNYCGTY 305
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Cavefish
Match: dlc (deltaC [Source:NCBI gene;Acc:30120])

HSP 1 Score: 77.411 bits (189), Expect = 9.906e-14
Identity = 36/105 (34.29%), Postives = 52/105 (49.52%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  R+D  GHY CD+   ++ C+E W G  C  P C + C+  +G C     C C+ GW G  C++C     C +G C +   CIC  GW G  C+ +  +  N 
Sbjct:  201 CRPRDDTFGHYTCDSTGNRV-CLEGWKGEYCADPICSSGCSEEHGYCETPGECKCRLGWQGPQCDECTRYPGCSHGTCDQPWQCICKEGWGGLFCNQDLNFCTNH 304
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Cavefish
Match: dlc (deltaC [Source:NCBI gene;Acc:30120])

HSP 1 Score: 77.411 bits (189), Expect = 1.120e-13
Identity = 36/105 (34.29%), Postives = 52/105 (49.52%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  R+D  GHY CD+   ++ C+E W G  C  P C + C+  +G C     C C+ GW G  C++C     C +G C +   CIC  GW G  C+ +  +  N 
Sbjct:  201 CRPRDDTFGHYTCDSTGNRV-CLEGWKGEYCADPICSSGCSEEHGYCETPGECKCRLGWQGPQCDECTRYPGCSHGTCDQPWQCICKEGWGGLFCNQDLNFCTNH 304
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Cavefish
Match: tenm4 (teneurin transmembrane protein 4 [Source:NCBI gene;Acc:103031446])

HSP 1 Score: 77.411 bits (189), Expect = 1.580e-13
Identity = 41/103 (39.81%), Postives = 55/103 (53.40%), Query Frame = 3 
Query: 1908 PKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADC-NNGICVQINHCFCKYGWTGKYCNKCVTSKDCL-NGACVEGNDCICSAGWIGSNCDIEG 2210
            P+  C  +    G ++ D  T   SC  NWTG++C T  C ADC  +G+CV    C C+ GWTG  C++      C  +G C +G  C CS GW G +C IEG
Sbjct:  730 PRASCMDQCSGHGAFLAD--TGTCSCDPNWTGHDCSTELCAADCGGHGVCVA-GGCRCEEGWTGAGCDQRACHSRCSEHGTCKDGK-CECSPGWNGEHCTIEG 828
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Sea Lamprey
Match: JAG1 (jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188])

HSP 1 Score: 68.9366 bits (167), Expect = 1.009e-11
Identity = 37/108 (34.26%), Postives = 57/108 (52.78%), Query Frame = 3 
Query: 1917 VCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCK--YGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            +C  R+D  GHY CD+   K+ C++ WTG +C    C+  C+  +G C     C C+  YGW G +C++C+    C++G C +  +C C   W G  CD +  Y  N 
Sbjct:   60 LCKPRDDYFGHYACDSNGNKV-CLDGWTGGDCKKAICRQGCSTEHGQCDNPGECNCRCQYGWQGHFCDQCIPYPGCVHGGCSKPWECRCDTNWGGLLCDKDLNYCGNH 166
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Sea Lamprey
Match: VWDE (von Willebrand factor D and EGF domains [Source:HGNC Symbol;Acc:HGNC:21897])

HSP 1 Score: 65.4698 bits (158), Expect = 1.153e-10
Identity = 34/87 (39.08%), Postives = 45/87 (51.72%), Query Frame = 3 
Query: 1944 GHYVCDNLTKKMSCMENWTGNNCLTPKCKADC-NNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGA-CVEGNDCICSAGWIGSNC 2198
            GH + +N+  K    E +TG  C    C+  C N+G CV  N C C  G+ GK CN+ V  + C NG  C+  N C C  GW G +C
Sbjct: 1476 GHCMRNNICSKG---EGYTGRRCQKSVCEPTCMNSGKCVGPNVCSCPSGFKGKRCNRPVCLQKCKNGGECIGPNSCHCPEGWEGMHC 1559

HSP 2 Score: 64.6994 bits (156), Expect = 1.994e-10
Identity = 29/75 (38.67%), Postives = 40/75 (53.33%), Query Frame = 3 
Query: 1983 CMENWTGNNCLTPKCKADC-NNGICVQINHCFCKYGWTGKYCNKCVTSKDCLN-GACVEGNDCICSAGWIGSNCD 2201
            C   +TG NCL   C+ DC N G CV+ + C C  G+ G  C +   +  C N GAC+  N C C  G++G  C+
Sbjct: 1326 CKPGYTGYNCLIAVCRPDCKNQGKCVRPDVCECPLGYKGPICEEVECTPTCQNAGACIARNLCSCPYGYLGPRCE 1400

HSP 3 Score: 61.6178 bits (148), Expect = 1.738e-9
Identity = 31/75 (41.33%), Postives = 36/75 (48.00%), Query Frame = 3 
Query: 1980 SCMENWTGNNCLTPKCKADCNNG-ICVQINHCFCKYGWTGKYCNKCVTSKDCLN-GACVEGNDCICSAGWIGSNC 2198
            SC   + G  C T  C   C NG  CV  + C C  GW G  C   V S  CLN GACV    C+C  G+ G+ C
Sbjct: 1389 SCPYGYLGPRCETMVCNRHCENGGECVSPDVCRCSPGWDGPTCGSAVCSPVCLNGGACVRPGVCLCPHGFFGAQC 1463

HSP 4 Score: 60.077 bits (144), Expect = 6.253e-9
Identity = 34/101 (33.66%), Postives = 41/101 (40.59%), Query Frame = 3 
Query: 1902 RLPKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNG-ICVQINHCFCKYGWTGKYCNKCVTSKDC-LNGACVEGNDCICSAGWIGSNC 2198
            R  K+VC       G  V  N+    SC   + G  C  P C   C NG  C+  N C C  GW G +C   V  + C   G C   N C C  G+ G  C
Sbjct: 1494 RCQKSVCEPTCMNSGKCVGPNVC---SCPSGFKGKRCNRPVCLQKCKNGGECIGPNSCHCPEGWEGMHCQNPVCQQTCKFGGRCTAPNACSCRPGFSGFAC 1591

HSP 5 Score: 55.0694 bits (131), Expect = 1.684e-7
Identity = 30/101 (29.70%), Postives = 43/101 (42.57%), Query Frame = 3 
Query: 1902 RLPKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADC-NNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGA-CVEGNDCICSAGWIGSNC 2198
            R    VC+   +  G  V  ++ +   C   W G  C +  C   C N G CV+   C C +G+ G  C+  + S  C NG  C+  N C    G+ G  C
Sbjct: 1398 RCETMVCNRHCENGGECVSPDVCR---CSPGWDGPTCGSAVCSPVCLNGGACVRPGVCLCPHGFFGAQCHNAICSPPCKNGGHCMRNNICSKGEGYTGRRC 1495

HSP 6 Score: 53.5286 bits (127), Expect = 5.477e-7
Identity = 27/75 (36.00%), Postives = 36/75 (48.00%), Query Frame = 3 
Query: 1983 CMENWTGNNCLTPKCKADCNNG-ICVQINHCFCKYGWTGKYCNKCVTSKDCLN-GACVEGNDCICSAGWIGSNCD 2201
            C   + G  C    C   C NG  C++ N C    G+TG+ C K V    C+N G CV  N C C +G+ G  C+
Sbjct: 1454 CPHGFFGAQCHNAICSPPCKNGGHCMRNNICSKGEGYTGRRCQKSVCEPTCMNSGKCVGPNVCSCPSGFKGKRCN 1528
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001302.1 (pep scaffold:Pmarinus_7.0:GL479305:38781:187025:1 gene:ENSPMAG00000001162.1 transcript:ENSPMAT00000001302.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.7734 bits (151), Expect = 8.490e-10
Identity = 29/77 (37.66%), Postives = 43/77 (55.84%), Query Frame = 3 
Query: 1980 SCMENWTGNNCLTPKCKADCN-NGICVQINHCFCKYGWTGKYCNKCVTSKDCL-NGACVEGNDCICSAGWIGSNCDI 2204
            SC   +TG +C T  C  DC  +G+C+    C C+ GW G+ C++    + C  +GAC +G  C CS GW G +C +
Sbjct:  284 SCDARFTGADCSTELCPVDCGAHGVCIG-GSCHCQEGWGGETCDQKACHRHCAEHGACRDGK-CECSQGWNGEHCSV 358

HSP 2 Score: 52.373 bits (124), Expect = 1.497e-6
Identity = 27/99 (27.27%), Postives = 35/99 (35.35%), Query Frame = 3 
Query: 1944 GHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGAC---VEGND----------CICSAGWIGSNCD 2201
             H VC  +     C E W G  C    C   C      +   C C  GW G++C+    + +C    C     GN           C+C  GW G  CD
Sbjct:  305 AHGVC--IGGSCHCQEGWGGETCDQKACHRHCAEHGACRDGKCECSQGWNGEHCSVGKVTANCCQKGCPAMCSGNGECRLAQGSWLCVCVPGWRGPGCD 401
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009276.1 (pep scaffold:Pmarinus_7.0:GL476916:212692:218299:-1 gene:ENSPMAG00000008391.1 transcript:ENSPMAT00000009276.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 52.373 bits (124), Expect = 8.557e-8
Identity = 38/109 (34.86%), Postives = 50/109 (45.87%), Query Frame = 3 
Query: 1881 SKYIKNSRLPKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADC-NNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGA-CVEGNDCICSAGWIGSNCD 2201
              Y +N+     +C       GH + +N+    SC E + G  C    C   C N G CV  N C C  GW GK CNK +  + C NG  C+  N C+C  GW G+ C 
Sbjct:   28 GPYCQNA---TAICSPACKNGGHCMRNNVC---SCPEGYMGKRCQESVCDPTCLNGGKCVGPNICSCPSGWKGKKCNKPMCLQKCKNGGECIRPNTCLCPPGWEGAQCQ 130
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009665.1 (pep scaffold:Pmarinus_7.0:GL480729:2444:4403:-1 gene:ENSPMAG00000008736.1 transcript:ENSPMAT00000009665.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.521 bits (114), Expect = 6.827e-6
Identity = 30/78 (38.46%), Postives = 40/78 (51.28%), Query Frame = 3 
Query: 1983 CMENWTGNNCLTPKCKADCNN-GICVQINHCFCKYGWTGKYCNKCVTSKDCLN-GACVEGNDCICSAGWIGSNCDIEG 2210
            C + WTG  C  P C +DC   G CV    C C+ G++G  C +     DC N G CV G  C+C  G+ G++C   G
Sbjct:  135 CDKGWTGKACSQPACPSDCGGRGTCVD-GVCDCEDGFSGPDCGQAACLNDCSNRGVCVSGG-CVCERGFAGTDCSQPG 210
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Nematostella
Match: DELTA (Delta-like protein [Source:UniProtKB/TrEMBL;Acc:A7SL28])

HSP 1 Score: 75.485 bits (184), Expect = 1.007e-14
Identity = 38/90 (42.22%), Postives = 49/90 (54.44%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTG-NNCLTPKCKADCN-NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGW 2183
            C  R+D+ GH  CD     + C+  W G   C TP C   C  NG CV  + C C+ GWTG  CN+CV    C++G C +  DCIC+ GW
Sbjct:  161 CEPRDDKFGHMTCDANGTHV-CLPGWQGLPYCTTPVCSKSCRPNGNCVSPDRCSCQGGWTGPQCNQCVPHPACVHGTCNKPFDCICTPGW 249
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Nematostella
Match: EDO28502 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6A3])

HSP 1 Score: 57.7658 bits (138), Expect = 1.002e-9
Identity = 27/70 (38.57%), Postives = 35/70 (50.00%), Query Frame = 3 
Query: 1995 WTGNNCLTPKCKADC-NNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGA-CVEGNDCICSAGWIGSNC 2198
            WTG  C  P C   C + G CV+ N C C+ G+ GK C K +    C NG  C+    C C+ G+ G  C
Sbjct:   56 WTGVRCQLPVCMFPCLHGGRCVRPNQCSCQSGYYGKMCEKAICKDSCFNGGRCIRPGTCACAFGFTGPRC 125

HSP 2 Score: 51.9878 bits (123), Expect = 9.471e-8
Identity = 29/76 (38.16%), Postives = 38/76 (50.00%), Query Frame = 3 
Query: 1983 CMENWTGNNCLTPKCKADC-NNGICVQINHCFCKYG-WTGKYCNKCVTSKDCLNGA-CVEGNDCICSAGWIGSNCD 2201
            C + + G  C  P C++ C N G CV+ N C C    WTG  C   V    CL+G  CV  N C C +G+ G  C+
Sbjct:   19 CSQWFVGEQCEFPVCRSTCLNGGRCVKPNVCLCDSRFWTGVRCQLPVCMFPCLHGGRCVRPNQCSCQSGYYGKMCE 94
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Nematostella
Match: EDO31040 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZ23])

HSP 1 Score: 54.299 bits (129), Expect = 1.465e-8
Identity = 34/78 (43.59%), Postives = 40/78 (51.28%), Query Frame = 3 
Query: 1983 CMENWTGNNCLTPKCKADC-NNGICVQINHCFCKYGWTGKYCN--KCVTSKDCLN-GACVEGNDCICSAGWIGSNCDI 2204
            C   + G  CLTP CK  C N G CV  N C C  G+ G  C   KC+ S  CLN G+CV    C C  G+ G  C+I
Sbjct:   43 CRAGYEGPLCLTPVCKPSCVNGGYCVGSNTCRCLRGFEGWRCEHMKCMVS--CLNGGSCVGPYLCNCLPGYTGHRCEI 118

HSP 2 Score: 46.595 bits (109), Expect = 6.157e-6
Identity = 26/75 (34.67%), Postives = 36/75 (48.00%), Query Frame = 3 
Query: 1983 CMENWTGNNCLTPKCKADC-NNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGA-CVEGNDCICSAGWIGSNCD 2201
            C + + G  C    C+  C N G CV+ + C C+ G+ G  C   V    C+NG  CV  N C C  G+ G  C+
Sbjct:   11 CPKGYYGIGCRRAFCRNGCYNGGECVRPDVCKCRAGYEGPLCLTPVCKPSCVNGGYCVGSNTCRCLRGFEGWRCE 85
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Nematostella
Match: EDO35570 (Delta-like protein [Source:UniProtKB/TrEMBL;Acc:A7SL30])

HSP 1 Score: 50.447 bits (119), Expect = 1.407e-7
Identity = 30/76 (39.47%), Postives = 38/76 (50.00%), Query Frame = 3 
Query: 1914 TVCHTRNDEL-GHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNN--GICVQINHCFCKYGWTGKYCNKCVTSKDC 2132
            T C  R+D   GHY CD+ T    C   WTG+NC TP CK+ C++  G C     C C  GW    C +C+    C
Sbjct:   15 TYCIPRDDNYNGHYTCDSNTGNKICRSYWTGSNCRTPICKSGCSSVHGFCYTPQTCECYSGWRLPDCTQCIPKPGC 90
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Nematostella
Match: EDO47365 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RML5])

HSP 1 Score: 53.9138 bits (128), Expect = 7.106e-7
Identity = 33/104 (31.73%), Postives = 42/104 (40.38%), Query Frame = 3 
Query: 1911 KTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLN--------GACVEGNDCICSAGWIGSNC 2198
            K  C  RND  GH+ CD  + +  C+E WTG+NC       D   G  V      C+ GW     N     K+C          G   E  + +C  GW G NC
Sbjct:  228 KKECTPRNDTGGHFGCDPESGEKLCLEGWTGSNCTQGHYVCDYVQGRKV------CREGWYDAVSNCTKKKKECTPRNDTGGHYGCDPESGEKLCLGGWTGPNC 325
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Medaka
Match: dlb (delta-like protein B [Source:NCBI gene;Acc:101165992])

HSP 1 Score: 87.4261 bits (215), Expect = 6.427e-17
Identity = 44/105 (41.90%), Postives = 54/105 (51.43%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQ 2228
            C  R+D LGHY CD    ++ C+E W GN C  P C ADC+  NG C     C C+ GW G  C +CV    CL+G C +   C C  GW G  CD +  Y  N 
Sbjct:  171 CRPRDDTLGHYTCDEEGSRV-CLEGWKGNYCSEPICSADCSERNGYCEAPGGCTCRMGWQGPSCTECVRYPGCLHGTCGQPWQCNCQEGWGGLFCDQDLNYCTNH 274
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Medaka
Match: jag1b (jagged canonical Notch ligand 1 [Source:NCBI gene;Acc:101168394])

HSP 1 Score: 82.8037 bits (203), Expect = 3.120e-15
Identity = 40/102 (39.22%), Postives = 58/102 (56.86%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYL 2219
            C  R++  GHY CD    K +C+E W+G +C T  C+  C+  +G+C +   C C YGW G+YC+KC+    C++G CVE   C+C   W G  CD +  Y 
Sbjct:  195 CRPRDEFFGHYTCDGNGNK-TCLEGWSGPDCNTAICRQGCSTEHGLCKEPGGCDCLYGWQGQYCDKCIPHPGCVHGTCVEPWQCLCETNWGGHLCDKDLNYC 295
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Medaka
Match: jag1b (jagged canonical Notch ligand 1 [Source:NCBI gene;Acc:101168394])

HSP 1 Score: 82.4185 bits (202), Expect = 3.849e-15
Identity = 40/102 (39.22%), Postives = 58/102 (56.86%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYL 2219
            C  R++  GHY CD    K +C+E W+G +C T  C+  C+  +G+C +   C C YGW G+YC+KC+    C++G CVE   C+C   W G  CD +  Y 
Sbjct:  169 CRPRDEFFGHYTCDGNGNK-TCLEGWSGPDCNTAICRQGCSTEHGLCKEPGGCDCLYGWQGQYCDKCIPHPGCVHGTCVEPWQCLCETNWGGHLCDKDLNYC 269
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Medaka
Match: jag1b (jagged canonical Notch ligand 1 [Source:NCBI gene;Acc:101168394])

HSP 1 Score: 82.4185 bits (202), Expect = 3.902e-15
Identity = 40/102 (39.22%), Postives = 58/102 (56.86%), Query Frame = 3 
Query: 1920 CHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYL 2219
            C  R++  GHY CD    K +C+E W+G +C T  C+  C+  +G+C +   C C YGW G+YC+KC+    C++G CVE   C+C   W G  CD +  Y 
Sbjct:  195 CRPRDEFFGHYTCDGNGNK-TCLEGWSGPDCNTAICRQGCSTEHGLCKEPGGCDCLYGWQGQYCDKCIPHPGCVHGTCVEPWQCLCETNWGGHLCDKDLNYC 295
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Medaka
Match: ENSORLT00000022384.2 (protein jagged-2 [Source:NCBI gene;Acc:101163046])

HSP 1 Score: 81.2629 bits (199), Expect = 1.047e-14
Identity = 43/103 (41.75%), Postives = 55/103 (53.40%), Query Frame = 3 
Query: 1917 VCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCN--NGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYL 2219
            VC  R+D  GHYVCD  +   +CME WTG +C T  CK  C+  +G C     C CKYGW G  C++C+    C +G C E  +C C   W G  CD +  Y 
Sbjct:  203 VCRPRDDYFGHYVCDQ-SGNRNCMEGWTGPDCKTAICKPGCHSIHGTCSVPGECKCKYGWDGLLCDQCLPYPGCFHGTCNEPWECSCEKNWGGLLCDKDLNYC 304
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Planmine SMEST
Match: SMESG000041500.1 (SMESG000041500.1)

HSP 1 Score: 3271.87 bits (8482), Expect = 0.000e+0
Identity = 1707/1732 (98.56%), Postives = 1714/1732 (98.96%), Query Frame = 3 
Query:  261 MNRNEIVTFVSIFLVMMISTGDSVEYFIYMPNTIVSNSVHNVPVYLSHPPAIISFSYPSKFDPIQRFLLIETLNDVSLEIFNSNISATVLSIQITLSTCGSIEDCYTNQTLQVLTSKTYQIPLSKKSHLIQLATSKGCYSSNXXXXXXXXXXXXXXXXNRKFSNVYRIEWENGRFVPKTRLYSKLKPKSEILKLTLSDTNNITIKSWSKNSQDKSFNVEYILPKDSVSGTWKIAYQLSNTNQQDFHEFELRSEDEKPVNAKMNISIKYNGDITIMTRNIQFFVCAEYSKFRSVKGKLSGTICLKYPEEELTTERPCLMFESYMNGSSKCVWIETSTDGLQLKNISYSQRLSRLIISVDIIDEYSKKNHLYHYMGPTLKNSKYKISFLSSPYFKSMLPYYGRIQTLQHNDKPFSNASIVIQCNTVNFPYNWGHYSKHVSDKDGNIYFILSSPPVNLEIITCDIEDLSFTEEKSIHVRYYRSSITQTLERSKSSKKKNIQLKLLDRKMXXXXXXXXXXXXQSNNVVTEDLMILLVGNGQIIKSKYIKNSRLPKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQTKLHRKLVKKSIPIKEIKTTEINLIFTAIINLKIPSMMSAVTVIVHXXXXXXXXXXXXXEPIYSFIKDNIGFGHMKTQNCIHYDWYQPLKATLGGITAIDSKNIPIQNSIYDEIAIEQCTIPFNEVPNFSKVQLNTNIVTQFSPAENDDFLNVFQSLNLFPITTLKIVSRTCPLWKIISTINKTNALFPKNRTIYVTQNPTQNIKKNNRYQNCQCEADCNNVYSEMFQINQSVEPVLVSSLCVDSSKTKKISVINHLITIKPSFLVTISTINYLKXXXXXXXXXXXFNLLRSDLEIEIISKSRAKCLVGEFNXXXXXXXXPQQTFKVLQDVQFNCPGIFQIFFHFQTKHSNRTFPSISNDTVSYPIKRTEKILYKVYNVTLFKQTNNYQYCRNEIKNSSVSIEMFKEPYVPSYVSFKIQIQSGLERFLEYLRYIYQNQNLDNIVTLTMRIYELNLTKYLKNKKFLNHSLISIKKMIEVESKVLKSIQRSLPFDYAALLLNLCTDIPNHLYNIKRKFCKLLENKLILSQFNENNCTDFRGKFDEIVFLASISLTKESKYFQPKNKTKFNFIQSCLMKSNSGPESKIYLNHIENVMKNDSHSLKNWLNINENSLNLNQLAFLSIITKDNPKFNPIRNRTVKKILQKISNNPKGISKIKAIVLLKVLAENEENLPNSFHFGKSNQTTAESTKEFSDWSKYQKLSVELPKYFSCSNIKVESEYFTEIFNGKINDDFIDLEEKSNDCNSTELFLTVKTQLKKLKSIIIHLPTGWMIEKLKIDSISTQLLPCNIFLKNKNDLFQVEFDFYLALPECHINKIPLKLFRYQAISNLQPSYATVTNEKNFLFHKKFSIKYCPKNSPPLLRNQFKTLHKLTTIKELCDKYQEILITFNDKFLTIEDRKIIIKKTKESLVDNKILFLNKEKSAIEKKINTIFQWFLRNSNLESCENGQIIRNLLNSHSNWLTAPENRSNCVTIELDLVTNESFYQIICRKLINVYSIRSIDLNKNSITLKQLIEPCNVKSKLKSEFKIDFIVDYSCXXXXXXXXXXXXXXXXXXXXDLQTARNPLKLNNKYLLVTME 5456
            MNRNEIVTFVSIFLVMMISTGDSVEYFIYMPNTIVSNSVHNVPVYLSHPPAIISFSYPSKFDPIQRFLLIETLNDVSLEI NSNISATVL IQITLSTCGSIEDCYTNQTLQVLTSKTYQIPLSKKSHLIQLATSKGCYSS+EKLLISVIIIRIEEILNRKFSNVYRIEWENGRFVPKTRLYSKLKPKSEILKLTLSDTNNITIKSWSKNS+DKSFNVEYILPKDSVSGTWKIAYQLSNTNQQDFHEFELRSEDEKPVNAKMNI IKYNGDITIMTRNIQFFVCAEYSKFRSVKGKLSGTICLKYPEEELTTERPCL FESYMNGSSKCVWIETSTDGLQLKNISYSQRLSRLIISVDIIDEYSKKNHLYHYMGPTLKNSKYKISFLSSPYFKSMLPYYGRIQTLQHNDKPFSNASIVIQCNTVNFPYNWGHYSKHVSDKDGNIYFILSSPPVNLEIITCDIEDLSFTEEKSIHVRYYRSSITQTLERSKSSKKKNIQLKLLDRKMLIKN+ELIKLELQSNNVVTEDLMILLVGNGQIIKSKYIKNS LPKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQTKLHRKLVKKSIPIKEIKTTEINLIFTAIINLKIPSMMSAVTVIVHSVSKSPSSSKLLLEPIYSFIKDNIGFGHMKTQNCIHYD YQPLKATLGGITAID KNIPIQNSIY+EIAIEQCTIPFNEVPNFSKVQLNTNIVTQFSPAENDDFLNVFQSLNLFPITTLKIVSRTCPLWKIISTINKTNALFPK RTIYVTQNPTQNIKKNNRY+NCQCEADCNNVYSEMFQINQSVEPVLVSSLCVDSSKTKKISVINHLITIKPSFLVTISTINYLKIHEIHHQIIEIFNLLRSDLEIEIISKSRAKCLVGEFNKTIIIKIKPQQTFKV+QDVQFNCPGIFQIFFHFQTKHSNRTFPSISNDTVSYPIKRTEKILYKVYNVTLFKQTNNYQYCRNEIKNSSVSIEMFKEPYVPSYVSFKIQIQSGLERFLEYLRYIYQNQNLDNIVTLTMRIYELNLTKYLKNKKFLNHSLISIKKMIEVESKV KSIQRSLPFDYAALLLNLCTDIPNHLYNIKRKFCKLLENKLILSQFNENNCTDFRGKFDEIVFLASISLTKESKYFQ KNKTKFNFIQSCLMKSNSGPESKIYLNHIENVMKNDSHSLKNWLNINENSLNLNQLAFLSIITKDNPKFNPIRNRTVKKILQKISNNPKGISKIKAIVLLKVLAENEENLPNSFHFGKSNQTTAESTKEFSDWSKYQKLSVELPKYFSCSNIKVESEYFTEIFNGKINDDFIDLEEKSNDCNSTELFLTVK QLK LKSIIIHLPTGWMIEKL IDSISTQLLPCNIFLKNKNDLFQVEFDFYLAL ECHINKIPLKLFRYQAISNLQPSYAT+TNEKN LFHKKFSIKYCPKN PPLLRNQFKTLHKLTTIKELCDKYQEILI FND FLTIEDRKIIIKKTKESLVDNKILFLNKEKSAIEKKINTIFQWFLRNSNLESCENGQIIRNLLNSHSNWLTAPENRSNCVTIELDLVTNESFYQIICRKLINVYSIRSIDLNKNSITLKQLIEPCNVKSKLKSEFKIDFIVDYSCESLKKISKFSKESFLFLSILDLQTARNPLKLNNKYLLVTME
Sbjct:    1 MNRNEIVTFVSIFLVMMISTGDSVEYFIYMPNTIVSNSVHNVPVYLSHPPAIISFSYPSKFDPIQRFLLIETLNDVSLEICNSNISATVLPIQITLSTCGSIEDCYTNQTLQVLTSKTYQIPLSKKSHLIQLATSKGCYSSSEKLLISVIIIRIEEILNRKFSNVYRIEWENGRFVPKTRLYSKLKPKSEILKLTLSDTNNITIKSWSKNSEDKSFNVEYILPKDSVSGTWKIAYQLSNTNQQDFHEFELRSEDEKPVNAKMNICIKYNGDITIMTRNIQFFVCAEYSKFRSVKGKLSGTICLKYPEEELTTERPCLTFESYMNGSSKCVWIETSTDGLQLKNISYSQRLSRLIISVDIIDEYSKKNHLYHYMGPTLKNSKYKISFLSSPYFKSMLPYYGRIQTLQHNDKPFSNASIVIQCNTVNFPYNWGHYSKHVSDKDGNIYFILSSPPVNLEIITCDIEDLSFTEEKSIHVRYYRSSITQTLERSKSSKKKNIQLKLLDRKMLIKNQELIKLELQSNNVVTEDLMILLVGNGQIIKSKYIKNSHLPKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQTKLHRKLVKKSIPIKEIKTTEINLIFTAIINLKIPSMMSAVTVIVHSVSKSPSSSKLLLEPIYSFIKDNIGFGHMKTQNCIHYDQYQPLKATLGGITAIDPKNIPIQNSIYNEIAIEQCTIPFNEVPNFSKVQLNTNIVTQFSPAENDDFLNVFQSLNLFPITTLKIVSRTCPLWKIISTINKTNALFPKTRTIYVTQNPTQNIKKNNRYRNCQCEADCNNVYSEMFQINQSVEPVLVSSLCVDSSKTKKISVINHLITIKPSFLVTISTINYLKIHEIHHQIIEIFNLLRSDLEIEIISKSRAKCLVGEFNKTIIIKIKPQQTFKVVQDVQFNCPGIFQIFFHFQTKHSNRTFPSISNDTVSYPIKRTEKILYKVYNVTLFKQTNNYQYCRNEIKNSSVSIEMFKEPYVPSYVSFKIQIQSGLERFLEYLRYIYQNQNLDNIVTLTMRIYELNLTKYLKNKKFLNHSLISIKKMIEVESKVFKSIQRSLPFDYAALLLNLCTDIPNHLYNIKRKFCKLLENKLILSQFNENNCTDFRGKFDEIVFLASISLTKESKYFQSKNKTKFNFIQSCLMKSNSGPESKIYLNHIENVMKNDSHSLKNWLNINENSLNLNQLAFLSIITKDNPKFNPIRNRTVKKILQKISNNPKGISKIKAIVLLKVLAENEENLPNSFHFGKSNQTTAESTKEFSDWSKYQKLSVELPKYFSCSNIKVESEYFTEIFNGKINDDFIDLEEKSNDCNSTELFLTVKNQLKNLKSIIIHLPTGWMIEKLTIDSISTQLLPCNIFLKNKNDLFQVEFDFYLALTECHINKIPLKLFRYQAISNLQPSYATITNEKNVLFHKKFSIKYCPKNYPPLLRNQFKTLHKLTTIKELCDKYQEILIKFNDTFLTIEDRKIIIKKTKESLVDNKILFLNKEKSAIEKKINTIFQWFLRNSNLESCENGQIIRNLLNSHSNWLTAPENRSNCVTIELDLVTNESFYQIICRKLINVYSIRSIDLNKNSITLKQLIEPCNVKSKLKSEFKIDFIVDYSCESLKKISKFSKESFLFLSILDLQTARNPLKLNNKYLLVTME 1732
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Planmine SMEST
Match: SMESG000037203.1 (SMESG000037203.1)

HSP 1 Score: 204.142 bits (518), Expect = 2.781e-52
Identity = 185/718 (25.77%), Postives = 325/718 (45.26%), Query Frame = 3 
Query:  261 MNRNEIVTFVSIFLVMMISTGDSVEYFIYMPNTIVSNSVHNVPVYLSHPPAIISFSYPSKFDPIQ------RFLLIETLNDVSLEI-FNSNISATVLSIQITLSTCGSIEDC-YTNQTLQVLTSKTYQIPLSKKSHLIQLATSKGCYSSNXXXXXXXXXXXXXXXXNRKFSNVYRIEW---ENGRFVPKTRLYSKLKPKSEILKLTLSDT-NNITIKSWSKNSQDKSFNVEYILPKDSVSGTWKIAYQLSNTNQQDFHEFELRSEDEKPVNAKMNISIKYNGDITIMTRNIQFFVCAEYSKFRSVKGKLSGTICLKYPEEELTTERPCLMFES-YMNGSSKCVWIETSTDGLQLKNISYSQRLSRLIISVDIIDEYSKKNHLYHYMGPTLKNSKYKISFLSSPYFKSMLPYYGRIQTLQHNDKPFSNASIVIQCNTVNFPYNWGHYSKHVSDKDGNIYFILSSPPVNLEIITCDIEDLSFTEEKSIHVRYYRSSITQTLERSKSSKKKNIQLKLLDRKMXXXXXXXXXXXXQSNNVVTEDLMILLVGNGQIIKSKYIKNSRLPKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEG--TYLQNQTKLHRKLVKKSIPIKEIKTTEINLIFTAIINLKI-PSMMSAVTVIVH 2366
            MN   ++T +   +  + +  D   YFI  PN +++ + H+  V   H    I  +  S  DP Q      +F++ +    +   + F  +   + + + I    C S   C  T        ++T +I L  K+ +I   T K  Y   +K+ +  + I    ++        ++E    +N +F+ K    SK    S    L + +T +N+ +  W   S +++ N+EY L KD + G WK         Q++  +FE++    K V  +  + +    +I     +I F VC++YS  + +  K+SG  C+ Y        + C+ F+S  M  +   + +E+    +   +  YS+  S+  I+V + +  +  +      GP +K + + I F   PY+K  LPY+GRI  ++HN KP    +I I   +  +  NWG    + S+K G I F++   P+  + ++  I ++S   +  +      ++  Q L   +S     +Q   ++ K     +  + L    + + +  + + +   GQI+K   I+   +P   C+ R+D  GHY C N T  ++C+  W G NC  P C  DC NG CV+ N C CK  WTGK CN+C+ +K C NG CV G DC C  GW+  +C  +G   +L       + + K      EI+  E   IF  II++ +  +M   V VI +
Sbjct:    1 MNSVVLITIIISIVTKVFAVKDF--YFITSPNLLITETSHHFNV---HTSTDIVLTIESIHDPSQIKHQSSKFVIKKGFQTIPYYVPFVGSHLGSKIRLNILGDVCQSGMKCELTKNITGNFINETREIGLIDKNFIIFAETDKPIYKPGDKVRLRFMAIYPTNLMREPEEIGKQVEIVLDKNNKFISKP---SKNDNDSNYFDLIIIETPDNVRVAQWKNVSINEAMNLEYQLNKDPIFGIWKAKAVFDG--QEEIIQFEIK----KYVLPRFIVEVIPPSEILAKDESISFKVCSKYSTGKPMNAKISGMFCMLYS----YGTKKCVAFKSDLMKQNCNKIKLESKIVFILASSFRYSKAKSQ--INVTVTENGTSSSVSKAVEGPGIKYNSFNIKFDGRPYYKPGLPYFGRINLVRHNKKPAKMVNISISIQSWEYGNNWGFIRNYTSNKKGVIDFVIPYIPL-AQSLSIQISEVSSNLKPPMTA----TTSYQLLTNFQSKDGHYLQFMPINDKFKCPGKLNLTLLTNYD-IASTSIYVQIFSRGQIVK--MIEYPSVP-VKCYPRDDFFGHYQCVNGTT-LTCLSGWKGGNCREPICSGDCLNGACVEPNKCICKQYWTGKGCNRCIKAKYCKNGYCVNGGDCECYPGWMNFDCSKKGPIKHLYRNVTTVKPITKNET---EIRKFEKQTIFERIISIPLMKNMGPDVHVIAY 685
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Planmine SMEST
Match: SMESG000037144.1 (SMESG000037144.1)

HSP 1 Score: 201.445 bits (511), Expect = 1.239e-51
Identity = 183/695 (26.33%), Postives = 313/695 (45.04%), Query Frame = 3 
Query:  336 YFIYMPNTIVSNSVHNVPVYLSHPPAIISFSYPSKFDPIQ------RFLLIETLNDVSLEI-FNSNISATVLSIQITLSTCGSIEDC-YTNQTLQVLTSKTYQIPLSKKSHLIQLATSKGCYSSNXXXXXXXXXXXXXXXXNRKFSNVYRIEWENGRFVP----KTRLY--SKLKPKSEILKLTLSDT-NNITIKSWSKNSQDKSFNVEYILPKDSVSGTWKIAYQLSNTNQQDFHEFELRSEDEKPVNAKMNISIKYNGDITIMTRNIQFFVCAEYSKFRSVKGKLSGTICLKYPEEELTTERPCLMFESYMNGSSKCVWIETSTDGLQLKNISYSQRLSRLIISVDIIDEYSKKNHLYHYMGPTLKNSKYKISFLSSPYFKSMLPYYGRIQTLQHNDKPFSNASIVIQCNTVNFPYNWGHYSKHVSDKDGNIYFILSSPPVNLEIITCDIEDLSFTEEKSIHVRYYRSSITQTLERSKSSKKKNIQLKLLDRKMXXXXXXXXXXXXQSNNVVTEDLMILLVGNGQIIKSKYIKNSRLPKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEG--TYLQNQTKLHRKLVKKSIPIKEIKTTEINLIFTAIINLKI-PSMMSAVTVIVH 2366
            YFI  PN +++ ++H   V   H    I  +  S  DP Q      +F++ +    +   + F  +   + + + I    C S   C  T        ++T +I L  K+ +I   T K  Y   +K+ +  + I          +N+ R   E G+ V     KT  +  SK +       L + +T +N+ +  W   S +++ N+EY L KD + G WK         Q++  +FE++    K V  +  + +     I     +I F VC++YS  + +  K++G  C+          + C+ F+S +     C  I+  ++ L L + +Y    S+  I+V + +  +  +      GP +  + + I F S PY+K  LPY+GRI  ++HN KP    +I I   +  +  NWG    + S+K G I F++   P+  + ++  I ++S      I      +S+ Q+L   +S     +Q   + +K     +  + L    + + +  + + +   GQI+K   I+   +P   C+ R+D  GHY C N T  ++C+  W G NC  P C  DC NG CV+ N C CK  WTGK CN+C  +K C NG CV G DC C  GW+  +C  +G   +L       + + K      EI+  E   IF  +I++ +  +M   V VI +
Sbjct:   24 YFITTPNQLITETLHRFNV---HTSTDIVLTIESIHDPSQIKNQSSKFIIKKGFQTIPYYVPFVGSHLGSKIRLNILGDVCQSGMKCELTKNITGNFINETREIGLIDKNFIIFAETDKPIYKPGDKVRLRFMAIYP--------TNLMREPDEIGKQVEIILDKTNKFVSSKTRKHFRFFHLIIIETPDNVRVAQWKNVSINEAMNLEYQLNKDPIFGIWKAKAVFDG--QEEIIQFEIK----KYVLPRFIVEVIPPSGILAKDESISFKVCSKYSTGKLMTAKINGIFCI-----FAYKRKKCVAFKSDL-LKQNCSRIKLESNTLNLTSFAYFTAKSQ--INVTVTENGTSSSVSKAVEGPGIMYNSFIIKFDSRPYYKPGLPYFGRINLVRHNKKPAKMVNISISIQSWAYGNNWGFSRNYTSNKKGVIDFVIPYIPL-AQSLSIRISEVS----NDIKPPMNPASLYQSLANFQSRDGHYLQFMPIKQKFKCPGKLNLTLLTNYD-IASTSIYVQIFSRGQIVK--MIEYPSVP-VKCYPRDDFFGHYQCVNGTT-LTCLSGWKGGNCREPICSGDCLNGACVEPNKCICKQYWTGKGCNRCTKAKYCKNGYCVNGGDCECYPGWMNFDCSKKGPIKHLYRNVTTVKPITKNET---EIRKFEKQTIFERMISIPLMKNMGPDVHVIAY 680
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Planmine SMEST
Match: SMESG000037154.1 (SMESG000037154.1)

HSP 1 Score: 189.889 bits (481), Expect = 1.660e-48
Identity = 142/506 (28.06%), Postives = 247/506 (48.81%), Query Frame = 3 
Query:  870 IKSWSKNSQDKSFNVEYILPKDSVSGTWKIAYQLSNTNQQDFHEFELRSEDEKPVNAKMNISIKYNGDITIMTRNIQFFVCAEYSKFRSVKGKLSGTICLKYPEEELTTERPCLMFESYMNGSSKCVWIETSTDGLQLKNISYSQRLSRLIISVDIIDEYSKKNHLYHYMGPTLKNSKYKISFLSSPYFKSMLPYYGRIQTLQHNDKPFSNASIVIQCNTVNFP---YNWGHYSKHVSDKDGNIYFILSSPPVNLEIITCDIEDLSFTEEKSIHVRYYRSSITQTLERSKSSKKKNIQLKLLDRKMXXXXXXXXXXXXQSNNVVTEDLMILLVGNGQIIKSKYIKNSRLPKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNNGICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSNCDIEGTYLQNQTKLHRKLVKKSIPIKEIKTT---EINLIFTAIINLK-IPSMMSAVTVIVH 2366
            +  W   + + + N+ Y L KD   G WK   +     Q++  EF +     K V  +  I+I     I     +I++ +CA+YS  + +  ++  T C+ Y      TE+      + +   + C  IE ST  +      Y    +R  I+V + +  +         G  + +++YKI F S PYFK  LPY+G ++ ++H++KP  N  I I   +V+FP     WG  S + SD++G + FI+ S   N  + T  I + S   E  I    +    ++ ++  +S  ++ +++  ++ K+    +  + +    + + + +L + ++  GQI+K+  I+   +P   C++R+D+LGHY C +  K + C+  W GNNC+ P C   C NG C   + C CK GW G+ C+KC+    C NG C  GNDC+C  GW   +C I+G +  N   L+  L K + P K+   T   E   IF  I+++  + +M   + VIV+
Sbjct:  205 VAQWRNLTIENAMNLNYQLSKDPAIGIWKA--KAIYRGQEEVMEFRVM----KYVLPRFIINITPPNQIMYKDSSIKYEICAQYSTKKKMIARIQTTFCIIY---YYVTEK--CQVTNLILKDTYCATIEVSTKSVFPAFNKYRFIRTRSRINVTVTENGTSSTISKSLDGNGIMDTEYKIVFNSKPYFKFGLPYFGNVKLIRHDNKPQRNTKIKI---SVDFPKRYVKWGFESNYSSDENGVVRFIIPSVISN-SLFTIQITEASDVIENVITTPIF----SRNIDPWESISEQVLEILPIENKIKCPGKLNLTVLTNYD-ISSTNLYVQILSRGQIVKA--IEYPPVP-IKCYSRDDDLGHYKCVD-DKTLQCLPGWKGNNCIEPICSRGCINGACTSHDKCVCKMGWVGETCDKCIKPAYCKNGNCNRGNDCVCLPGWTKYDCSIKG-FRYNNEPLYVPLSKYTEPPKKPAVTNKYENKSIFERILSIPLLKNMGPDIHVIVY 685
[Close]
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Planmine SMEST
Match: SMESG000037146.1 (SMESG000037146.1)

HSP 1 Score: 81.6481 bits (200), Expect = 1.945e-15
Identity = 67/250 (26.80%), Postives = 116/250 (46.40%), Query Frame = 3 
Query:  870 IKSWSKNSQDKSFNVEYILPKDSVSGTWKIAYQLSNTNQQDFHEFELRSEDEKPVNAKMNISIKYNGDITIMTRNIQFFVCAEYSKFRSVKGKLSGTICLKY---PEEELTTERPCLMFESYMNGSSKCVWIETSTDGLQLKNISYSQRLSRLIISVDIIDEYSKKNHLYHYMGPTLKNSKYKISFLSSPYFKSMLPYYGRIQTLQHNDKPFSNASIVIQCNTVNFPYNWGHYSKHVSDKDGNIYFILSS 1610
            +  W   + + + N+ Y L KD   G WK   +     Q++  EF +     K V  +  I+I     I     +I++ +CA+YS  + +  ++  T C+ Y   PE+   T    ++ ++Y      C  IE ST  +      Y    +R  I+V + +  +         G  + +++YKI F S PYFK  LPY+G ++ ++H++KP  N  I I  +       WG  S + SD++G + FI+ S
Sbjct:  205 VAQWRNLTIENAMNLNYQLSKDPAIGIWKA--KAIYRGQEEVMEFRVM----KYVLPRFIINITPPNQIMHKDSSIKYEICAQYSTKKKMIARIQTTFCIIYYYVPEKCQVTN--LILKDTY------CATIEVSTKSVFPAFNKYRFFRTRSRINVTVTENGTSSTISKSLDGNGIMDTEYKIVFNSKPYFKFGLPYFGNVKLIRHDNKPQINTKIKISVDFTIGYVKWGFESNYSSDENGVVRFIIPS 440
The following BLAST results are available for this feature:
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DLL45.904e-1537.38delta like canonical Notch ligand 4 [Source:HGNC S... [more]
JAG21.058e-1440.00jagged canonical Notch ligand 2 [Source:HGNC Symbo... [more]
JAG21.302e-1440.00jagged canonical Notch ligand 2 [Source:HGNC Symbo... [more]
JAG16.358e-1336.36jagged canonical Notch ligand 1 [Source:HGNC Symbo... [more]
DLK17.999e-1344.93delta like non-canonical Notch ligand 1 [Source:HG... [more]
back to top
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
T01D3.16.740e-1137.78pep chromosome:WBcel235:V:13689892:13703330:1 gene... [more]
apx-11.980e-1041.03Anterior pharynx in excess protein 1 [Source:UniP... [more]
ten-19.923e-835.06Teneurin-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ... [more]
ten-19.992e-835.06Teneurin-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ... [more]
ten-11.118e-735.06Teneurin-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ... [more]
back to top
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dl7.659e-1537.86gene:FBgn0000463 transcript:FBtr0083739[more]
Dl7.659e-1537.86gene:FBgn0000463 transcript:FBtr0083740[more]
Dl7.659e-1537.86gene:FBgn0000463 transcript:FBtr0304658[more]
Ser1.975e-1237.37gene:FBgn0004197 transcript:FBtr0344121[more]
Ser1.975e-1237.37gene:FBgn0004197 transcript:FBtr0085128[more]
back to top
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
jag1b2.516e-1541.18jagged canonical Notch ligand 1b [Source:NCBI gene... [more]
jag1a2.072e-1440.63jagged canonical Notch ligand 1a [Source:NCBI gene... [more]
jag1a2.100e-1440.63jagged canonical Notch ligand 1a [Source:NCBI gene... [more]
dlb7.237e-1438.10deltaB [Source:NCBI gene;Acc:30141][more]
dll42.391e-1339.58delta-like 4 (Drosophila) [Source:ZFIN;Acc:ZDB-GEN... [more]
back to top
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DLL41.406e-1437.25delta-like 4 [Source:NCBI gene;Acc:100489166][more]
DLL41.627e-1437.25delta-like 4 [Source:NCBI gene;Acc:100489166][more]
DLL41.741e-1437.25delta-like 4 [Source:NCBI gene;Acc:100489166][more]
DLL42.459e-1437.25delta-like 4 [Source:NCBI gene;Acc:100489166][more]
JAG22.482e-1436.96jagged 2 [Source:NCBI gene;Acc:100497180][more]
back to top
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Jag25.088e-1540.95jagged 2 [Source:MGI Symbol;Acc:MGI:1098270][more]
Jag12.427e-1437.19jagged 1 [Source:MGI Symbol;Acc:MGI:1095416][more]
Dll41.551e-1335.51delta like canonical Notch ligand 4 [Source:MGI Sy... [more]
Dll13.099e-1335.64delta like canonical Notch ligand 1 [Source:MGI Sy... [more]
Tenm31.182e-1136.45teneurin transmembrane protein 3 [Source:MGI Symbo... [more]
back to top
BLAST of Alpha-2-macroglobulin-like protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q90Y54|JAG1B_DANRE1.775e-1441.18Protein jagged-1b OS=Danio rerio OX=7955 GN=jag1b ... [more]
sp|Q9NR61|DLL4_HUMAN2.835e-1437.38Delta-like protein 4 OS=Homo sapiens OX=9606 GN=DL... [more]
sp|Q9QYE5|JAG2_MOUSE3.650e-1440.95Protein jagged-2 OS=Mus musculus OX=10090 GN=Jag2 ... [more]
sp|P97607|JAG2_RAT3.947e-1440.95Protein jagged-2 (Fragment) OS=Rattus norvegicus O... [more]
sp|Q9Y219|JAG2_HUMAN5.892e-1440.00Protein jagged-2 OS=Homo sapiens OX=9606 GN=JAG2 P... [more]
back to top
BLAST of Alpha-2-macroglobulin-like protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Y6HTR93.141e-4326.53Alpha-2-macroglobulin OS=Dugesia japonica OX=6161 ... [more]
A0A0V0J5K41.635e-2523.66Alpha-1-inhibitor 3 (Fragment) OS=Schistocephalus ... [more]
A0A183SB523.875e-2523.28Alpha-1-inhibitor 3 OS=Schistocephalus solidus OX=... [more]
A0A0X3Q5K47.953e-2523.47Uncharacterized protein (Fragment) OS=Schistocepha... [more]
A0A430PYA34.258e-2248.45Alpha-2-macroglobulin OS=Schistosoma bovis OX=6184... [more]
back to top
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dlb1.395e-1540.00deltaB [Source:NCBI gene;Acc:30141][more]
jag1b5.883e-1440.95jagged canonical Notch ligand 1 [Source:NCBI gene;... [more]
dlc9.906e-1434.29deltaC [Source:NCBI gene;Acc:30120][more]
dlc1.120e-1334.29deltaC [Source:NCBI gene;Acc:30120][more]
tenm41.580e-1339.81teneurin transmembrane protein 4 [Source:NCBI gene... [more]
back to top
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
JAG11.009e-1134.26jagged canonical Notch ligand 1 [Source:HGNC Symbo... [more]
VWDE1.153e-1039.08von Willebrand factor D and EGF domains [Source:HG... [more]
ENSPMAT00000001302.18.490e-1037.66pep scaffold:Pmarinus_7.0:GL479305:38781:187025:1 ... [more]
ENSPMAT00000009276.18.557e-834.86pep scaffold:Pmarinus_7.0:GL476916:212692:218299:-... [more]
ENSPMAT00000009665.16.827e-638.46pep scaffold:Pmarinus_7.0:GL480729:2444:4403:-1 ge... [more]
back to top
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
DELTA1.007e-1442.22Delta-like protein [Source:UniProtKB/TrEMBL;Acc:A... [more]
EDO285021.002e-938.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO310401.465e-843.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO355701.407e-739.47Delta-like protein [Source:UniProtKB/TrEMBL;Acc:A... [more]
EDO473657.106e-731.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dlb6.427e-1741.90delta-like protein B [Source:NCBI gene;Acc:1011659... [more]
jag1b3.120e-1539.22jagged canonical Notch ligand 1 [Source:NCBI gene;... [more]
jag1b3.849e-1539.22jagged canonical Notch ligand 1 [Source:NCBI gene;... [more]
jag1b3.902e-1539.22jagged canonical Notch ligand 1 [Source:NCBI gene;... [more]
ENSORLT00000022384.21.047e-1441.75protein jagged-2 [Source:NCBI gene;Acc:101163046][more]
back to top
BLAST of Alpha-2-macroglobulin-like protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000041500.10.000e+098.56SMESG000041500.1[more]
SMESG000037203.12.781e-5225.77SMESG000037203.1[more]
SMESG000037144.11.239e-5126.33SMESG000037144.1[more]
SMESG000037154.11.660e-4828.06SMESG000037154.1[more]
SMESG000037146.11.945e-1526.80SMESG000037146.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002925 ID=SMED30002925|Name=Alpha-2-macroglobulin-like protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=5535bp
GATCTAAAATGCCACCGAGGATTCATCACAGGGGAAATTAATCATCATTG
CCAAATTCTCCACCCACCCGAAGACTGATTTGTCCCCAATTCACACTACA
CGTGCGGCATAAGGTTAAAGTTGAATTTGCGTTTGTTTACTCTTGACAGC
ATTACTAATATAATCAAAATTTCATGTAAATAGCGGCGATTATCACATTA
ATTGCACCATAAACATGAATCCAGTGGTTGTGAAATTGTAAATTTATGAC
AAAATCAAACATGAATCGCAACGAAATCGTAACTTTTGTGAGTATATTTC
TTGTTATGATGATTTCAACAGGGGACTCTGTGGAATATTTCATATATATG
CCTAATACGATTGTCTCAAATTCAGTTCATAACGTTCCAGTGTATCTTTC
TCATCCTCCTGCTATCATATCTTTTTCTTACCCATCAAAATTTGATCCCA
TTCAAAGGTTCCTATTAATCGAAACTTTAAATGATGTGTCTTTAGAAATC
TTCAACTCGAATATATCGGCTACAGTTCTCTCCATTCAGATAACCTTGAG
TACATGTGGCAGCATTGAGGATTGCTATACAAATCAAACCTTACAAGTAT
TGACGTCTAAAACATATCAAATCCCTTTATCGAAAAAGAGCCATTTAATT
CAACTAGCCACCTCTAAAGGTTGCTATTCATCAAATGAAAAGTTATTAAT
TTCTGTAATTATTATTAGAATTGAAGAAATTCTAAATCGAAAATTCTCTA
ATGTCTACCGCATCGAATGGGAAAATGGGAGATTTGTTCCAAAAACAAGA
CTTTATTCAAAACTCAAGCCAAAATCTGAGATTTTAAAGTTAACTTTATC
CGATACTAACAATATAACTATCAAGAGTTGGTCGAAAAACTCTCAAGACA
AATCATTTAATGTTGAATATATCTTACCAAAGGATTCTGTGTCTGGAACA
TGGAAGATTGCCTACCAATTGTCAAATACAAATCAGCAGGACTTTCATGA
ATTCGAACTGAGATCAGAGGACGAGAAGCCAGTCAATGCAAAAATGAATA
TCAGTATCAAATATAACGGTGATATCACAATTATGACAAGAAATATTCAG
TTTTTCGTTTGCGCTGAATATTCAAAGTTTCGGTCAGTGAAGGGAAAACT
TTCAGGAACAATATGCTTGAAGTATCCCGAAGAAGAGTTAACAACTGAAA
GACCATGTCTAATGTTTGAATCTTATATGAATGGCTCATCAAAATGTGTT
TGGATTGAAACAAGCACAGACGGACTGCAGTTGAAAAATATATCGTATTC
ACAAAGGTTAAGCCGACTTATAATCAGCGTCGACATCATCGATGAATACT
CAAAAAAGAATCATCTTTATCATTATATGGGACCAACTTTGAAAAACAGT
AAATACAAAATCAGTTTTCTCTCAAGTCCATATTTCAAATCCATGCTTCC
TTATTATGGGAGAATCCAAACTTTGCAGCACAATGATAAACCATTCTCCA
ATGCATCCATTGTCATTCAATGTAACACGGTTAATTTCCCTTACAATTGG
GGTCATTACAGTAAGCATGTCTCAGATAAAGACGGAAACATTTATTTCAT
TTTGTCCTCACCTCCTGTCAATTTGGAAATTATAACCTGCGACATTGAGG
ACCTCTCGTTTACGGAGGAGAAATCCATACACGTTAGATACTATCGGTCA
TCTATCACTCAAACCTTGGAGAGGTCAAAATCCTCGAAAAAGAAAAATAT
CCAACTGAAACTTTTGGATCGAAAAATGTTAATAAAAAATGAAGAATTAA
TTAAATTAGAACTTCAATCCAACAACGTTGTAACGGAAGATTTGATGATA
CTATTGGTGGGAAATGGGCAAATCATCAAGTCAAAATACATCAAAAACTC
TCGCCTGCCAAAAACCGTTTGTCACACACGCAACGATGAGCTCGGTCATT
ATGTTTGCGATAATTTGACAAAGAAAATGAGTTGTATGGAAAATTGGACC
GGAAATAATTGCCTGACTCCGAAATGCAAAGCGGATTGCAATAACGGAAT
CTGCGTACAAATTAATCATTGTTTTTGCAAATACGGATGGACAGGTAAAT
ACTGTAACAAATGCGTCACGAGTAAAGATTGTTTAAATGGAGCATGCGTC
GAAGGAAATGACTGTATTTGTTCTGCCGGCTGGATTGGATCCAATTGTGA
TATCGAAGGAACTTATTTACAAAACCAAACAAAACTCCATCGAAAACTTG
TGAAGAAATCTATTCCCATAAAAGAGATTAAAACAACGGAAATTAATTTA
ATTTTTACTGCGATAATTAATTTGAAAATACCTTCAATGATGTCTGCGGT
GACCGTTATAGTCCATTCGGTATCTAAAAGCCCATCTTCTTCGAAGTTAT
TGTTGGAACCCATTTATAGTTTTATTAAAGATAATATTGGCTTTGGTCAT
ATGAAAACACAAAATTGTATTCATTATGATTGGTATCAACCGCTAAAAGC
AACTTTAGGCGGCATTACAGCAATAGATTCGAAGAATATTCCAATTCAAA
ACTCAATTTACGACGAGATCGCTATAGAACAATGTACGATCCCATTCAAT
GAGGTTCCAAACTTTTCCAAGGTACAATTAAACACGAATATTGTAACACA
GTTCTCTCCAGCGGAAAATGATGATTTCCTCAATGTATTCCAATCTTTGA
ATCTTTTCCCCATAACTACACTAAAAATTGTCAGTCGAACATGTCCATTG
TGGAAAATTATTTCGACTATCAACAAAACCAACGCTTTATTCCCGAAAAA
TCGCACAATTTATGTCACTCAAAATCCGACCCAAAACATTAAAAAAAACA
ACAGATATCAAAACTGTCAATGTGAAGCCGATTGCAACAATGTTTACAGT
GAAATGTTTCAGATAAATCAATCCGTTGAACCCGTTTTGGTGTCCTCACT
CTGCGTTGATAGCTCAAAAACGAAAAAAATTTCCGTTATAAACCACCTGA
TCACCATAAAACCCTCGTTTCTGGTAACAATCTCGACAATAAATTACCTA
AAGATTCATGAAATTCATCATCAAATCATCGAAATATTTAATTTGCTAAG
GTCCGACCTGGAAATCGAAATAATATCGAAATCAAGAGCCAAATGTCTTG
TTGGAGAATTCAACAAGACAATTATAATAAAGATAAAACCTCAGCAAACA
TTCAAAGTACTACAAGATGTTCAGTTTAACTGTCCGGGGATTTTCCAAAT
ATTCTTCCATTTCCAAACCAAACACTCGAATAGAACCTTTCCATCCATCT
CGAACGATACCGTCTCGTATCCAATTAAGAGAACCGAGAAAATTCTTTAT
AAAGTTTATAACGTGACATTATTTAAACAAACAAATAATTACCAATATTG
CCGAAACGAAATCAAAAACTCATCAGTCAGCATAGAAATGTTCAAAGAGC
CTTACGTTCCCAGTTATGTCAGCTTTAAAATCCAGATTCAAAGTGGTCTC
GAAAGATTTCTCGAATATTTGAGATACATTTACCAAAATCAAAACCTTGA
CAACATTGTCACATTGACTATGAGAATTTACGAGTTGAATTTGACAAAGT
ATTTGAAAAATAAAAAATTTCTCAACCACTCGTTAATTAGTATCAAAAAA
ATGATTGAAGTTGAAAGTAAAGTCCTCAAAAGTATACAACGCTCTTTACC
GTTCGATTATGCGGCCTTATTGTTGAATCTCTGTACGGATATTCCCAATC
ATTTGTATAACATTAAAAGGAAATTCTGTAAACTCCTCGAAAATAAATTA
ATATTATCTCAGTTCAACGAGAATAATTGTACAGATTTCCGAGGAAAATT
TGATGAAATTGTTTTCTTGGCATCCATTTCTCTTACAAAAGAATCGAAAT
ATTTTCAACCGAAAAACAAAACCAAATTCAACTTTATCCAATCCTGCTTG
ATGAAATCAAATTCCGGTCCGGAATCAAAGATTTATCTTAACCACATCGA
AAACGTAATGAAAAATGATTCTCATTCATTGAAAAATTGGTTGAATATCA
ATGAAAATTCATTGAATCTAAATCAGTTGGCTTTTCTTTCCATCATAACA
AAAGACAACCCAAAATTTAATCCAATTCGTAATAGAACAGTGAAAAAAAT
CCTCCAAAAAATCAGTAACAATCCAAAAGGAATTTCCAAAATCAAAGCGA
TTGTTTTATTAAAGGTTTTAGCAGAAAATGAAGAAAATTTACCGAATAGT
TTTCATTTTGGAAAATCAAATCAAACTACCGCCGAATCAACAAAGGAATT
TTCTGATTGGTCAAAATATCAAAAGTTAAGCGTAGAATTACCGAAATATT
TTTCATGCTCCAACATTAAAGTAGAGTCGGAATATTTCACAGAAATATTC
AACGGAAAAATCAATGACGATTTTATTGATTTGGAAGAGAAATCGAACGA
CTGCAATTCTACAGAATTGTTTTTGACTGTGAAAACTCAATTGAAAAAAT
TAAAATCAATTATTATCCATTTGCCGACCGGTTGGATGATTGAAAAATTA
AAAATTGATTCGATTTCAACACAACTTTTACCATGTAACATATTTTTAAA
AAATAAAAATGATCTTTTCCAGGTGGAATTCGATTTTTATCTAGCACTCC
CGGAATGCCATATTAATAAAATCCCCTTGAAATTGTTCCGATATCAAGCG
ATATCAAATCTTCAACCGAGCTATGCGACAGTTACAAATGAAAAAAATTT
CCTGTTCCATAAAAAATTTTCCATCAAATATTGCCCCAAAAATTCCCCGC
CGTTGCTTAGAAATCAATTCAAAACTCTCCATAAATTAACTACAATAAAA
GAATTGTGTGACAAATATCAAGAAATTCTAATTACATTCAATGACAAATT
TCTGACAATAGAAGACCGGAAAATTATTATTAAAAAAACCAAAGAATCTT
TAGTCGACAACAAAATTCTATTTCTAAATAAAGAAAAAAGTGCCATAGAA
AAGAAAATAAATACAATTTTTCAATGGTTTTTAAGAAATTCCAATTTGGA
ATCGTGTGAAAATGGACAGATTATTAGAAATCTCCTTAATTCGCATTCCA
ATTGGTTGACGGCACCGGAAAATCGGTCGAATTGCGTGACGATTGAACTG
GACCTGGTAACGAATGAATCATTTTATCAAATAATTTGTAGAAAATTAAT
CAATGTTTATTCCATCCGATCGATTGATTTAAACAAGAATTCGATAACAT
TAAAACAATTAATTGAACCTTGTAATGTAAAATCGAAACTGAAAAGTGAA
TTCAAAATTGATTTTATTGTTGATTATTCGTGCGAATCTTTGAAAAAGAT
TTCAAAATTCTCTAAAGAAAGCTTTCTTTTTTTAAGCATTTTGGATTTGC
AGACAGCTCGAAACCCGTTGAAATTAAATAATAAATATTTGCTGGTTACT
ATGGAGAATATATGAATTTTTACATTTGCCTGAAATATTTTCCGTGTAAT
TTTATTGTGGTATTATATTTAGTAAATTTTGTACG
back to top

protein sequence of SMED30002925-orf-1

>SMED30002925-orf-1 ID=SMED30002925-orf-1|Name=SMED30002925-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1740bp
MTKSNMNRNEIVTFVSIFLVMMISTGDSVEYFIYMPNTIVSNSVHNVPVY
LSHPPAIISFSYPSKFDPIQRFLLIETLNDVSLEIFNSNISATVLSIQIT
LSTCGSIEDCYTNQTLQVLTSKTYQIPLSKKSHLIQLATSKGCYSSNEKL
LISVIIIRIEEILNRKFSNVYRIEWENGRFVPKTRLYSKLKPKSEILKLT
LSDTNNITIKSWSKNSQDKSFNVEYILPKDSVSGTWKIAYQLSNTNQQDF
HEFELRSEDEKPVNAKMNISIKYNGDITIMTRNIQFFVCAEYSKFRSVKG
KLSGTICLKYPEEELTTERPCLMFESYMNGSSKCVWIETSTDGLQLKNIS
YSQRLSRLIISVDIIDEYSKKNHLYHYMGPTLKNSKYKISFLSSPYFKSM
LPYYGRIQTLQHNDKPFSNASIVIQCNTVNFPYNWGHYSKHVSDKDGNIY
FILSSPPVNLEIITCDIEDLSFTEEKSIHVRYYRSSITQTLERSKSSKKK
NIQLKLLDRKMLIKNEELIKLELQSNNVVTEDLMILLVGNGQIIKSKYIK
NSRLPKTVCHTRNDELGHYVCDNLTKKMSCMENWTGNNCLTPKCKADCNN
GICVQINHCFCKYGWTGKYCNKCVTSKDCLNGACVEGNDCICSAGWIGSN
CDIEGTYLQNQTKLHRKLVKKSIPIKEIKTTEINLIFTAIINLKIPSMMS
AVTVIVHSVSKSPSSSKLLLEPIYSFIKDNIGFGHMKTQNCIHYDWYQPL
KATLGGITAIDSKNIPIQNSIYDEIAIEQCTIPFNEVPNFSKVQLNTNIV
TQFSPAENDDFLNVFQSLNLFPITTLKIVSRTCPLWKIISTINKTNALFP
KNRTIYVTQNPTQNIKKNNRYQNCQCEADCNNVYSEMFQINQSVEPVLVS
SLCVDSSKTKKISVINHLITIKPSFLVTISTINYLKIHEIHHQIIEIFNL
LRSDLEIEIISKSRAKCLVGEFNKTIIIKIKPQQTFKVLQDVQFNCPGIF
QIFFHFQTKHSNRTFPSISNDTVSYPIKRTEKILYKVYNVTLFKQTNNYQ
YCRNEIKNSSVSIEMFKEPYVPSYVSFKIQIQSGLERFLEYLRYIYQNQN
LDNIVTLTMRIYELNLTKYLKNKKFLNHSLISIKKMIEVESKVLKSIQRS
LPFDYAALLLNLCTDIPNHLYNIKRKFCKLLENKLILSQFNENNCTDFRG
KFDEIVFLASISLTKESKYFQPKNKTKFNFIQSCLMKSNSGPESKIYLNH
IENVMKNDSHSLKNWLNINENSLNLNQLAFLSIITKDNPKFNPIRNRTVK
KILQKISNNPKGISKIKAIVLLKVLAENEENLPNSFHFGKSNQTTAESTK
EFSDWSKYQKLSVELPKYFSCSNIKVESEYFTEIFNGKINDDFIDLEEKS
NDCNSTELFLTVKTQLKKLKSIIIHLPTGWMIEKLKIDSISTQLLPCNIF
LKNKNDLFQVEFDFYLALPECHINKIPLKLFRYQAISNLQPSYATVTNEK
NFLFHKKFSIKYCPKNSPPLLRNQFKTLHKLTTIKELCDKYQEILITFND
KFLTIEDRKIIIKKTKESLVDNKILFLNKEKSAIEKKINTIFQWFLRNSN
LESCENGQIIRNLLNSHSNWLTAPENRSNCVTIELDLVTNESFYQIICRK
LINVYSIRSIDLNKNSITLKQLIEPCNVKSKLKSEFKIDFIVDYSCESLK
KISKFSKESFLFLSILDLQTARNPLKLNNKYLLVTMENI*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000019muscle progenitor cell
PLANA:0000101muscle cell
PLANA:0000478pharynx musculature
PLANA:0002142parenchyma
PLANA:0003116parenchymal cell
PLANA:0007547anterior pole progenitor cell
Vocabulary: INTERPRO
TermDefinition
IPR040839MG4
IPR013783Ig-like_fold
IPR000742EGF-like_dom
IPR013032EGF-like_CS
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0004866endopeptidase inhibitor activity
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region
GO:0005615extracellular space
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0007154cell communication
GO:0007275multicellular organism development
GO:0010951negative regulation of endopeptidase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000742EGF-like domainSMARTSM00181egf_5coord: 593..621
e-value: 3.3
score: 16.7
coord: 622..652
e-value: 0.067
score: 22.3
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 585..621
score: 8.137
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 625..652
score: 7.465
NoneNo IPR availableGENE3DG3DSA:2.60.40.1930coord: 183..258
e-value: 1.8E-6
score: 30.2
NoneNo IPR availableGENE3DG3DSA:2.10.25.140coord: 556..591
e-value: 1.0E-7
score: 33.9
NoneNo IPR availableGENE3DG3DSA:2.10.25.10coord: 594..657
e-value: 1.2E-12
score: 49.8
NoneNo IPR availablePANTHERPTHR11412MACROGLOBULIN/COMPLEMENTcoord: 122..548
NoneNo IPR availableTMHMMTMhelixcoord: 12..34
IPR040839Macroglobulin domain MG4PFAMPF17789MG4coord: 393..477
e-value: 1.6E-6
score: 28.2
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 387..480
e-value: 3.4E-5
score: 25.8
IPR013032EGF-like, conserved sitePROSITEPS00022EGF_1coord: 640..651
IPR013032EGF-like, conserved sitePROSITEPS00022EGF_1coord: 609..620
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 640..651