Lipase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002911 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Lipase vs. Ensembl Human
Match: LIPA (lipase A, lysosomal acid type [Source:HGNC Symbol;Acc:HGNC:6617]) HSP 1 Score: 328.946 bits (842), Expect = 2.599e-108 Identity = 175/397 (44.08%), Postives = 243/397 (61.21%), Query Frame = 2
Query: 269 VPCLLIVSIN----GGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTS-SPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYG-FVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYN 1441
V CL++ +++ GG L+ DPE M+V+E+I Y+G+P E + V TEDGYIL + RIP+GR + S KPVVFLQHGLL S WV N SL FILAD GFDVW+GNSRGNT+SRKH S FW F++DEMA++DLPASIN+ L + +++ Y+GHSQGT IGF FSQ +L ++ F AL PV + + + + L D ++I EFLP + + VC + CGN+ FLL G+N NLN +R+ +Y TH PAGTS +N+ H++Q+ KFQ FD+G N YNQ PP Y + +P A++ GG+DW+A DVN + ++ N+ + IPE+ H+DFIWG +A R+Y +I+ + KY
Sbjct: 9 VVCLVLWTLHSEGSGGKLTA---VDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPD--HLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQI-TNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ 399
BLAST of Lipase vs. Ensembl Human
Match: LIPF (lipase F, gastric type [Source:HGNC Symbol;Acc:HGNC:6622]) HSP 1 Score: 308.531 bits (789), Expect = 2.331e-100 Identity = 162/383 (42.30%), Postives = 244/383 (63.71%), Query Frame = 2
Query: 302 GLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGI-KKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTT---GE--FLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGF-VINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFL 1429
G L PG PEVTM+++++I Y+GYP E ++V TEDGYIL + RIPYG+ +S ++PVVFLQHGLL S+ W++N P SLAFILAD G+DVWLGNSRGNT++R++ +SP S FW F++DEMA++DLPA+I++ + + +L Y+GHSQGT IGF FS L ++ F ALAPV +KY L + + +++ G+ F P+ ++ VC +M +L C N F++ G++ +N N +R+ +Y++H PAGTS +N+ H+ Q+ S KFQ +D+G V N++ Y+Q PP Y + +P+A++ GG D +A +DV + +L N+ K IP YNH+DFIW +A +Y D++ +
Sbjct: 22 GKLHPG---SPEVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVA-------TVKYTKSLINKLRFVPQSLFKFIFGDKIFYPHNFFDQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPKL-PNLIYHKEIPFYNHLDFIWAMDAPQEVYNDIVSMI 393
BLAST of Lipase vs. Ensembl Human
Match: LIPF (lipase F, gastric type [Source:HGNC Symbol;Acc:HGNC:6622]) HSP 1 Score: 308.916 bits (790), Expect = 2.352e-100 Identity = 162/383 (42.30%), Postives = 244/383 (63.71%), Query Frame = 2
Query: 302 GLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGI-KKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTT---GE--FLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGF-VINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFL 1429
G L PG PEVTM+++++I Y+GYP E ++V TEDGYIL + RIPYG+ +S ++PVVFLQHGLL S+ W++N P SLAFILAD G+DVWLGNSRGNT++R++ +SP S FW F++DEMA++DLPA+I++ + + +L Y+GHSQGT IGF FS L ++ F ALAPV +KY L + + +++ G+ F P+ ++ VC +M +L C N F++ G++ +N N +R+ +Y++H PAGTS +N+ H+ Q+ S KFQ +D+G V N++ Y+Q PP Y + +P+A++ GG D +A +DV + +L N+ K IP YNH+DFIW +A +Y D++ +
Sbjct: 32 GKLHPG---SPEVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVA-------TVKYTKSLINKLRFVPQSLFKFIFGDKIFYPHNFFDQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPKL-PNLIYHKEIPFYNHLDFIWAMDAPQEVYNDIVSMI 403
BLAST of Lipase vs. Ensembl Human
Match: LIPK (lipase family member K [Source:HGNC Symbol;Acc:HGNC:23444]) HSP 1 Score: 304.679 bits (779), Expect = 7.270e-99 Identity = 161/390 (41.28%), Postives = 238/390 (61.03%), Query Frame = 2
Query: 278 LLIVSINGGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPG--IKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFV-INKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
+L++ G G +PE M+++++I Y+GYP E + VTT+DGYIL + RIP+GR PG KP V+LQHGL+ S+ W+ N P SLAF+LAD G+DVWLGNSRGNT+SRKH K SP S +W F+ DEMA++DLPA+IN+ + + +L Y+GHSQGT I F FS +L K+ F ALAPVV + ++ +K + L V+ F P+ ++ VC ++ C N F L G++ +NLN +R+ +Y++H PAGTS +N+ H+AQ+ S + Q FD+G N + ++Q+TPP Y + +P A++ GG D +A +DV + ++ N+ K IP YNH+DF G +A IY D+I + +Y
Sbjct: 11 MLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYDVTTKDGYILGIYRIPHGR-GCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSR--RVVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDVENLLPQIA-NLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEY 396
BLAST of Lipase vs. Ensembl Human
Match: LIPM (lipase family member M [Source:HGNC Symbol;Acc:HGNC:23455]) HSP 1 Score: 301.982 bits (772), Expect = 1.611e-97 Identity = 154/379 (40.63%), Postives = 224/379 (59.10%), Query Frame = 2
Query: 314 PGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGI-KKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTG-----EFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKL-KYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFL 1429
P DPE M+++E+I++ GYP E ++V TEDGYIL++ RIP G +PVV LQHGL+ + W++N P SL FILAD GFDVW+GNSRGN +SRKH S FW F++DEMA+FDLPA IN+ L + +K+ Y+G+SQGT +GF FS +L K+ + ALAP+ +K+ G F ++ + G EFL + + + ++CG + C N+ LL G+N N+N +R +Y H AGTS +NI H++Q+ S + + FD+G L K NQ TP +Y + +P AM+ GG DW++ EDV + E+ N+ K IPE+ H+DFIWG +A R+Y ++I +
Sbjct: 37 PTKAVDPEAFMNISEIIQHQGYPCEEYEVATEDGYILSVNRIPRGLVQPKKTGSRPVVLLQHGLVGGASNWISNLPNNSLGFILADAGFDVWMGNSRGNAWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQEKIYYVGYSQGTTMGFIAFSTMPELAQKIKMYFALAPI-------ATVKHAKSPGTKFLLLPDMMIKGLFGKKEFLYQTRFLRQLVIYLCGQVILDQICSNIMLLLGGFNTNNMNMSRASVYAAHTLAGTSVQNILHWSQAVNSGELRAFDWGSETKNLEKCNQPTPVRYRVRDMTVPTAMWTGGQDWLSNPEDVKMLLSEV-TNLIYHKNIPEWAHVDFIWGLDAPHRMYNEIIHLM 407
BLAST of Lipase vs. Ensembl Celegans
Match: lipl-1 (Lipase [Source:UniProtKB/TrEMBL;Acc:Q93789]) HSP 1 Score: 306.605 bits (784), Expect = 5.401e-100 Identity = 172/382 (45.03%), Postives = 226/382 (59.16%), Query Frame = 2
Query: 317 GIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRT--SSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFS-DLNSKVSAFVALAPVVYLGNLKTAIKYIAG-LGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVC-GDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAI------GELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFL 1429
G + DPE+ M ++I +GYP + VTTEDGYIL + RIPYG+T + P KKPVVF+QHGL SS WV N P +S AF+ AD G+DVWLGN RGNTYS KH P FWD++WDEM Q+DLPA I AL V+ D L YIGHSQGT F++ S+ +K+ F ALAPV + ++K A+K+ A F+ +GEFLPN ++ +S+ VC G ++ + C +V FL+ G LN TR+PIYV H PAGTS++NI H+ Q K+DYG NK Y Q P Y T PV +++G +DW+A DV + + QN KLI +YNH+DFIWG A IY +ID +
Sbjct: 20 GHDADPEMKMTTPQIIMRWGYPAMIYDVTTEDGYILELHRIPYGKTNVTWPNGKKPVVFMQHGLECSSSNWVVNLPTESAAFLFADAGYDVWLGNFRGNTYSMKHKNLKPSHSAFWDWSWDEMQQYDLPAMIEKALEVTGQDSLYYIGHSQGTLTMFSRLSEDKVGWGNKIKKFFALAPVGSVKHIKGALKFFADYFSLEFDGWFDVFGSGEFLPNNWIMKLVSESVCAGLKVEAGVCDDVMFLIAGPESNQLNATRVPIYVAHTPAGTSTQNIVHWIQMVRHGGTPKYDYGEKGNKKHYGQANVPAYDFTTVNRPVYLYWGDSDWLADPTDVTDFLLTHLNPSTVVQNNKLI----DYNHLDFIWGLRAPKDIYEPIIDIV 397
BLAST of Lipase vs. Ensembl Celegans
Match: lipl-6 (LIPase Like [Source:UniProtKB/TrEMBL;Acc:E2S7J2]) HSP 1 Score: 307.76 bits (787), Expect = 4.227e-98 Identity = 151/375 (40.27%), Postives = 225/375 (60.00%), Query Frame = 2
Query: 317 GIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRT----SSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGEL--GQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVID 1423
I DPE MDV E+I ++GYP+ETH+V T DGYILT+ RIP+G+ S+ KPVVFLQHGLL +S W+ N P +S +I AD+G+DVWLGN RGNTYS++HT+ + + FW F+W+EMA++DLPA INYAL +K L Y+GHSQG FAK S+ +++ K+ F A+APV + ++K + + + + +N++ + GEFL N ++ C + + C N F + G N N +R+ IY+ H PAGTSS+NI H+AQ + +FD+G +N Y +PP+Y + + +FY DW+A +DV + + + +K + ++NH DF+WG A IY +I+
Sbjct: 171 NITIDPEALMDVPEIITHWGYPVETHKVVTVDGYILTLHRIPHGKNETSKSASKTPKPVVFLQHGLLCTSSIWLLNLPRQSAGYIFADQGYDVWLGNMRGNTYSKEHTRMTSADRRFWKFSWEEMARYDLPAMINYALKTTKRQNLYYVGHSQGALTMFAKMSEDPEMSKKIRKFFAMAPVARMSHVKGLFQNLGQIYEQYNLVYQVFGDGEFLTNNIFTKLLTDIFCDQAVNNPLCENFIFAVSGPNSNQFNNSRIGIYLAHNPAGTSSRNILHFAQMVKKKRMSRFDHGKDLNLKIYGAPSPPEYDIRKINSSIYLFYSDFDWLANPKDVEGFLIPMLPSKTLKKATKLRDFNHNDFLWGMRARKEIYDKIIN 545
BLAST of Lipase vs. Ensembl Celegans
Match: lipl-2 (Lipase [Source:UniProtKB/TrEMBL;Acc:Q20449]) HSP 1 Score: 293.893 bits (751), Expect = 6.387e-95 Identity = 160/402 (39.80%), Postives = 231/402 (57.46%), Query Frame = 2
Query: 266 RVPCLLIVSINGGLLSPGI----ETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSS--PGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSD--LNSKVSAFVALAPVVYLGNLKTAIKYIA-GLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCG-DQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDT-HGLPVAMFYGGNDWMAVKEDVNRAI------GELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVI 1420
++ CL+ S LL I + DPE+ M+ +++I+ +GY E H VTTEDGYIL MQRIPYG+TS P K+PV+ LQHGLL + WV+N P +S AF+ AD GFDVWLGN RG TY RK+TK P FW F+WDEMAQ+D+PA +++ L ++ + L Y+GHSQGT I F ++ +D K+ + ALAP+ + N+K + Y A F+ + +FLP+ + +K +CG + + C N FL+ G + N +R IY + PAGTS++NI H+ Q + + FD+G INK KY Q TPP+Y G + +++ +DW+ D++ + + +NV L EYNH+DF WG NA +IY I
Sbjct: 6 QITCLICTSF---LLLQTINAHPDDDPELNMNTSQIIERWGYKAEVHTVTTEDGYILQMQRIPYGKTSVTWPNGKRPVILLQHGLLACASDWVDNLPTQSAAFVFADAGFDVWLGNVRGTTYGRKNTKLDPSETAFWQFSWDEMAQYDVPAMVDHVLAMTGQENLYYMGHSQGTLIMFTHLAKDTDGSFAKKIKRYFALAPIGAVKNIKGFLSYFAHKFSPEFDGWYELFGSKDFLPDNWITKMAAKDICGASEKEAELCDNELFLIGGPESDQWNASRTAIYSSQDPAGTSTQNIVHWMQMVRNGRVPAFDWGKKINKKKYGQDTPPEYDFGAIKGTKIHLYWSDDDWLGDPTDIHDFLLKELNPAVIAENVNL----KEYNHLDFTWGLNATFQIYDKAI 400
BLAST of Lipase vs. Ensembl Celegans
Match: lipl-5 (Lipase [Source:UniProtKB/TrEMBL;Acc:O61866]) HSP 1 Score: 280.411 bits (716), Expect = 9.307e-90 Identity = 158/382 (41.36%), Postives = 215/382 (56.28%), Query Frame = 2
Query: 317 GIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRT--SSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFS-DLNSKVSAFVALAPVVYLGNLKTAIKYIAG-LGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGD-QMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDT-HGLPVAMFYGGNDWMAVKEDV--------NRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVI 1420
G DPE+ M ++I+ +GYP + V T+DGYIL M RIP+G+T + P K+PVVF+QHGLL +S WV N P++S F+ AD GFDVWLGN RGNTYS KH P FWD++WDEMA +DL A IN+ L V+ D + Y+GHSQGT F+ S+ K+ F ALAP+ + ++K + + A F+ GEFLPN + +K +CG ++ + C NV FL+ G + N TR+P+Y TH PAGTS++NI H+ Q +D+G NK KY Q PP+Y G + +++ DW+A DV N AI + QN L P+YNH+DF WG A IY I
Sbjct: 18 GSHGDPELHMTTPQIIERWGYPAMIYTVATDDGYILEMHRIPFGKTNVTWPNGKRPVVFMQHGLLCASSDWVVNLPDQSAGFLFADAGFDVWLGNMRGNTYSMKHKDLKPSHSAFWDWSWDEMATYDLNAMINHVLEVTGQDSVYYMGHSQGTLTMFSHLSKDDGSFAKKIKKFFALAPIGSVKHIKGFLSFFANYFSLEFDGWFDIFGAGEFLPNNWAMKLAAKDICGGLKVEADLCDNVLFLIAGPESDQWNQTRVPVYATHDPAGTSTQNIVHWMQMVHHGGVPAYDWGTKTNKKKYGQANPPEYDFTAIKGTKIYLYWSDADWLADTPDVPDYLLTRLNPAI--VAQNNHL----PDYNHLDFTWGLRAPDDIYRPAI 393
BLAST of Lipase vs. Ensembl Celegans
Match: lipl-5 (Lipase [Source:UniProtKB/TrEMBL;Acc:O61866]) HSP 1 Score: 280.411 bits (716), Expect = 9.307e-90 Identity = 158/382 (41.36%), Postives = 215/382 (56.28%), Query Frame = 2
Query: 317 GIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRT--SSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFS-DLNSKVSAFVALAPVVYLGNLKTAIKYIAG-LGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGD-QMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDT-HGLPVAMFYGGNDWMAVKEDV--------NRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVI 1420
G DPE+ M ++I+ +GYP + V T+DGYIL M RIP+G+T + P K+PVVF+QHGLL +S WV N P++S F+ AD GFDVWLGN RGNTYS KH P FWD++WDEMA +DL A IN+ L V+ D + Y+GHSQGT F+ S+ K+ F ALAP+ + ++K + + A F+ GEFLPN + +K +CG ++ + C NV FL+ G + N TR+P+Y TH PAGTS++NI H+ Q +D+G NK KY Q PP+Y G + +++ DW+A DV N AI + QN L P+YNH+DF WG A IY I
Sbjct: 18 GSHGDPELHMTTPQIIERWGYPAMIYTVATDDGYILEMHRIPFGKTNVTWPNGKRPVVFMQHGLLCASSDWVVNLPDQSAGFLFADAGFDVWLGNMRGNTYSMKHKDLKPSHSAFWDWSWDEMATYDLNAMINHVLEVTGQDSVYYMGHSQGTLTMFSHLSKDDGSFAKKIKKFFALAPIGSVKHIKGFLSFFANYFSLEFDGWFDIFGAGEFLPNNWAMKLAAKDICGGLKVEADLCDNVLFLIAGPESDQWNQTRVPVYATHDPAGTSTQNIVHWMQMVHHGGVPAYDWGTKTNKKKYGQANPPEYDFTAIKGTKIYLYWSDADWLADTPDVPDYLLTRLNPAI--VAQNNHL----PDYNHLDFTWGLRAPDDIYRPAI 393
BLAST of Lipase vs. Ensembl Fly
Match: CG31871 (gene:FBgn0051871 transcript:FBtr0080104) HSP 1 Score: 286.574 bits (732), Expect = 1.667e-90 Identity = 149/395 (37.72%), Postives = 232/395 (58.73%), Query Frame = 2
Query: 281 LIVSINGGLLSPGIETDPEVTMDVN----EVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAI-KYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQ-MGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNV-KLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYNN 1444
+++S N L G +V D + ++I+ YGYP ETH V T+DGYIL M RIP + + P V L HG+LD+S TWV GP+ L ++L+D G+DVW+GNSRGN YS+ HT + + FWDFT+ EM ++DLPA+I+Y L+ + +++ YIGHSQGT I + S+ K+++ ALAP+ Y+ ++K+ + + + D R + EF+PN + + S+ VC D M C N+ FL+ GYN E LN T +P+ ++H P+G S K + H+ Q S F+KFD G++ N+L+YN++TPP Y L +PVA++Y ND + V+R EL + K + + +NH+DF+W + +Y ++ + + N
Sbjct: 52 VLLSSNPNLAGGGRNLKSDVLEDASLITPKLIRKYGYPSETHTVVTKDGYILEMHRIP-KKGAQP------VLLMHGILDTSATWVLMGPKSGLGYMLSDLGYDVWMGNSRGNRYSKNHTSLNSDYQEFWDFTFHEMGKYDLPANIDYILSKTGYEQVHYIGHSQGTAIFWVLCSEQPAYTQKITSMHALAPIAYIHDMKSPLFRTLVLFLDFLTAATRMLRITEFMPNTKFLVDHSQVVCHDNAMTQDVCSNILFLVAGYNSEQLNKTMLPVMLSHTPSGASIKQLEHFGQLMKSGHFRKFDRGYLRNQLEYNRMTPPDYDLSRVKVPVALYYSVNDLLVSTTGVDRLARELPNVIDKYLVPMERFNHLDFLWAIDVKPLVYNRLVRNVRRVEN 439
BLAST of Lipase vs. Ensembl Fly
Match: Lip3 (gene:FBgn0023495 transcript:FBtr0082771) HSP 1 Score: 276.174 bits (705), Expect = 3.630e-88 Identity = 140/369 (37.94%), Postives = 207/369 (56.10%), Query Frame = 2
Query: 347 DVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAI-KYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVC-GDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIP--EYNHIDFIWGANAYTRIYPDVIDFLLKYN 1441
D E I+ GYP+E H+V T D YILTM RIPY + +PV FL HG+L SS WV GPE+SLA++LAD G+DVW+GN+RGNTYS+ H + + + FW+F+W+E+ +D+PA I+Y L + ++ Y+GHSQGT + S+ + N K+ + L P Y+GN+K+ + + A + N I+ + EF+P+ + + +C + C N FL+ GY+ E L+Y + PAG S H+ Q + S KF+KFDY + N +Y PP Y L PV ++YG NDWM DV + EL N+ L +P ++ H+DFIWG A +Y +V+ + Y
Sbjct: 27 DCGERIEDDGYPMERHEVVTSDNYILTMHRIPYSPKTGESSNRPVAFLMHGMLSSSSDWVLMGPERSLAYMLADAGYDVWMGNARGNTYSKAHKYWPTYWQIFWNFSWNEIGMYDVPAMIDYVLAKTGQQQVQYVGHSQGTTVYLVMVSERPEYNDKIKSAHLLGPAAYMGNMKSPLTRAFAPILGQPNAIVEVCGSMEFMPSNKFKQDLGIEMCQATSPYADMCANEIFLIGGYDTEQLDYELLEHIKATSPAGASVNQNLHFCQEYNSGKFRKFDYTALRNPYEYGSYFPPDYKLKNAKAPVLLYYGANDWMCDVSDVRKLRDEL-PNMALDYLVPFEKWAHLDFIWGTEARKYVYDEVLKQMQSYE 394
BLAST of Lipase vs. Ensembl Fly
Match: Lip4 (gene:FBgn0032264 transcript:FBtr0080093) HSP 1 Score: 276.559 bits (706), Expect = 7.065e-88 Identity = 144/382 (37.70%), Postives = 224/382 (58.64%), Query Frame = 2
Query: 308 LSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKT-AIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGD-QMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNV-KLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYNN 1444
+ P I+ D ++ +IK YGYP E H + T+DGYILT+ RI + PG V L HGLLDSS TWV GP K L ++L D+G+DVW+ N RGNTYSRKH K+S FWDFT+ EM + D+PA+++Y L + +L YIGHSQGT + + S+ + K+ LAPV +L + ++ + ++A + +++++ + EFLP + ++ ++ +C + + C NV FL G++ LN T +P+ V H PAG S+K + H+ Q + S F+++D+G++ N Y I PP Y L+ VA++YG NDW+A EDV +L V K + E+NH+DFIWG +A ++ +++ + + N
Sbjct: 59 VDPNIQEDSH--LNTYSLIKKYGYPAENHTLETDDGYILTLHRI-----ARPGATP--VLLVHGLLDSSATWVMMGPNKGLGYLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAKFWDFTFHEMGKHDIPATMDYILNSTGVSQLHYIGHSQGTVVFWIMASEKPEYMDKIILMQGLAPVAFLKHCRSPVVNFLAEWHLSVSLVLKLIGVHEFLPKNEFISMFNRIICDETTITKEICSNVIFLTTGFDKLQLNETMLPVIVGHSPAGASTKQMQHFGQLNRSGGFRQYDHGWLRNHWIYGTIDPPSYHLENVRAKVALYYGQNDWLAPPEDVEMLNRKLPNVVEKYLVDDKEFNHLDFIWGIDARELLWDRMLEIMRNHEN 431
BLAST of Lipase vs. Ensembl Fly
Match: Lip4 (gene:FBgn0032264 transcript:FBtr0331672) HSP 1 Score: 276.559 bits (706), Expect = 1.080e-87 Identity = 144/382 (37.70%), Postives = 224/382 (58.64%), Query Frame = 2
Query: 308 LSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKT-AIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGD-QMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNV-KLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYNN 1444
+ P I+ D ++ +IK YGYP E H + T+DGYILT+ RI + PG V L HGLLDSS TWV GP K L ++L D+G+DVW+ N RGNTYSRKH K+S FWDFT+ EM + D+PA+++Y L + +L YIGHSQGT + + S+ + K+ LAPV +L + ++ + ++A + +++++ + EFLP + ++ ++ +C + + C NV FL G++ LN T +P+ V H PAG S+K + H+ Q + S F+++D+G++ N Y I PP Y L+ VA++YG NDW+A EDV +L V K + E+NH+DFIWG +A ++ +++ + + N
Sbjct: 73 VDPNIQEDSH--LNTYSLIKKYGYPAENHTLETDDGYILTLHRI-----ARPGATP--VLLVHGLLDSSATWVMMGPNKGLGYLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAKFWDFTFHEMGKHDIPATMDYILNSTGVSQLHYIGHSQGTVVFWIMASEKPEYMDKIILMQGLAPVAFLKHCRSPVVNFLAEWHLSVSLVLKLIGVHEFLPKNEFISMFNRIICDETTITKEICSNVIFLTTGFDKLQLNETMLPVIVGHSPAGASTKQMQHFGQLNRSGGFRQYDHGWLRNHWIYGTIDPPSYHLENVRAKVALYYGQNDWLAPPEDVEMLNRKLPNVVEKYLVDDKEFNHLDFIWGIDARELLWDRMLEIMRNHEN 445
BLAST of Lipase vs. Ensembl Fly
Match: CG8093 (gene:FBgn0033999 transcript:FBtr0339997) HSP 1 Score: 274.633 bits (701), Expect = 1.305e-87 Identity = 148/394 (37.56%), Postives = 225/394 (57.11%), Query Frame = 2
Query: 278 LLIVSINGGLLSPGI------ETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAG--LGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQ-MGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQN-VKLIKFIPE--YNHIDFIWGANAYTRIYPDVID 1423
+L+V + LS G+ +T ++ +++ +GY +E H+V T DGYILTM RIPY + + +PVVFL HGLL SS WV GP LA++L++ G+DVW+GN+RGNTYS++H SP + FW+F W ++ +DLPA ++Y L + +L Y+GHSQGT F S S++ + LAPV ++ ++++ + + G LG N + + EFLPN QL+N +C D+ + C N FLL G+N +N T +P + PAG S I HY Q + S F++FDYG NK +Y+ TPP+Y ++ +P ++Y ND+ A DV+R + + +K +PE +NHIDF+WG N +Y VI+
Sbjct: 1 MLVVQLIAVFLSLGLANALPADTGRASSVTTVTIVRGHGYEIEEHEVQTSDGYILTMHRIPYSKNTGYDGPRPVVFLMHGLLCSSSDWVLAGPHSGLAYLLSEAGYDVWMGNARGNTYSKRHASKSPLLQPFWNFEWHDIGIYDLPAMMDYVLYWTNVTQLTYVGHSQGTTSFFVLNSMIPRFKSRIRSAHLLAPVAWMEHMESPLATVGGPLLGQP-NAFVELFGSAEFLPNTQLMNLFGALLCSDEAISQFMCTNTLFLLGGWNSPYINETLLPDIMATTPAGCSVNQIFHYLQEYNSGYFRQFDYGSTRNKKEYSSKTPPEYDVEGIDVPTYLYYSDNDYFASLIDVDRLRYTMNPSALKSAYRMPEEKWNHIDFLWGLNIKEILYDRVIN 393
BLAST of Lipase vs. Ensembl Zebrafish
Match: lipf (lipase, gastric [Source:ZFIN;Acc:ZDB-GENE-040426-2737]) HSP 1 Score: 316.62 bits (810), Expect = 7.675e-104 Identity = 159/371 (42.86%), Postives = 230/371 (61.99%), Query Frame = 2
Query: 317 GIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFL 1429
G DPEV M+++E+I+++GYP E +V TEDGYIL++ RIP+G + KPVVFLQHGLL + WV N P SL F+LAD GFDVW+GNSRGNT+S KH P K +W F+ DEMA+ DLPA IN+ ++ +++ Y+GHSQGT I F FS +L SK+ F ALAPV +G K+ + ++ + + +I +F P +L+ + C + S+ CGNV FLL G++ +NLN +R P+Y TH PAGTS +N+ H+AQ+ S+K +DYG N YNQ TPP Y + +P A++ GG D +A +DV + ++ + V + I + H+DFIWG +A +Y +I+ +
Sbjct: 25 GTGLDPEVNMNISEIIRHWGYPAEEFEVVTEDGYILSINRIPHGVKNKNEEVKPVVFLQHGLLAAGSNWVTNLPNNSLGFVLADAGFDVWIGNSRGNTWSCKHVSLDPRQKEYWKFSHDEMAKKDLPAVINFITKMTGQEQIFYVGHSQGTTIAFMAFSTMPELASKIKMFFALAPVATVGMTKSPMTKLSVIPEF--LIWDLFGQKDFFPQNELIKFFATEFCSRKPLSVLCGNVFFLLCGFDEKNLNMSRTPVYTTHCPAGTSVQNMIHWAQAVKSSKLMAYDYGRAGNMAHYNQSTPPLYNIQDMTVPTAVWSGGQDTLADPKDVALLLTQIPKLV-YKRDIKHWEHLDFIWGMDAPQEMYEKMIEIM 392
BLAST of Lipase vs. Ensembl Zebrafish
Match: lipf (lipase, gastric [Source:ZFIN;Acc:ZDB-GENE-040426-2737]) HSP 1 Score: 316.62 bits (810), Expect = 7.675e-104 Identity = 159/371 (42.86%), Postives = 230/371 (61.99%), Query Frame = 2
Query: 317 GIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFL 1429
G DPEV M+++E+I+++GYP E +V TEDGYIL++ RIP+G + KPVVFLQHGLL + WV N P SL F+LAD GFDVW+GNSRGNT+S KH P K +W F+ DEMA+ DLPA IN+ ++ +++ Y+GHSQGT I F FS +L SK+ F ALAPV +G K+ + ++ + + +I +F P +L+ + C + S+ CGNV FLL G++ +NLN +R P+Y TH PAGTS +N+ H+AQ+ S+K +DYG N YNQ TPP Y + +P A++ GG D +A +DV + ++ + V + I + H+DFIWG +A +Y +I+ +
Sbjct: 25 GTGLDPEVNMNISEIIRHWGYPAEEFEVVTEDGYILSINRIPHGVKNKNEEVKPVVFLQHGLLAAGSNWVTNLPNNSLGFVLADAGFDVWIGNSRGNTWSCKHVSLDPRQKEYWKFSHDEMAKKDLPAVINFITKMTGQEQIFYVGHSQGTTIAFMAFSTMPELASKIKMFFALAPVATVGMTKSPMTKLSVIPEF--LIWDLFGQKDFFPQNELIKFFATEFCSRKPLSVLCGNVFFLLCGFDEKNLNMSRTPVYTTHCPAGTSVQNMIHWAQAVKSSKLMAYDYGRAGNMAHYNQSTPPLYNIQDMTVPTAVWSGGQDTLADPKDVALLLTQIPKLV-YKRDIKHWEHLDFIWGMDAPQEMYEKMIEIM 392
BLAST of Lipase vs. Ensembl Xenopus
Match: lipa (lipase A, lysosomal acid, cholesterol esterase [Source:NCBI gene;Acc:548564]) HSP 1 Score: 323.168 bits (827), Expect = 1.956e-105 Identity = 163/390 (41.79%), Postives = 238/390 (61.03%), Query Frame = 2
Query: 269 VPCLLIVSINGGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
VP + + G LL DPE TM+++E+I+Y GYP E ++V TEDGYIL++ RIP+G + KPVVFLQHGLL WV N SL FILAD G+DVW+GNSRGNT+SRKH SP + FW F++DE+A+ DLPA +++ + +++ Y+GHSQGT I F FS L K+ + LAPV + K+ + + L + +I GEFLP L+ ++ C + CGN+ FLL G+N +NLN +R+ +Y +H PAGTS +N+ H+ Q S + + FD+G N + YNQ TPP Y + +P A++ GGNDW+A ++DV + ++ N+ K IP++ H+DFIWG +A R+Y ++I + K+
Sbjct: 67 VPSRIRHGVAGDLL---YSADPEATMNISELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEEFWAFSYDELAKKDLPAVVDFITKKTGQEQIFYVGHSQGTTIAFIAFSSLPQLAKKIKMYFGLAPVATVKFSKSPLAKLGVLPEF--LIEELFGKGEFLPQTYLITWLATHFCTHAIADELCGNIFFLLSGFNEKNLNMSRVNVYSSHCPAGTSVQNMLHWRQGVRSGELKAFDFGTKGNMIHYNQTTPPFYHVRDMTVPTALWTGGNDWLADRKDVALLLTQV-SNLVYHKEIPDWEHLDFIWGLDAPERMYNEIIAMMKKF 450
BLAST of Lipase vs. Ensembl Xenopus
Match: lipa (lipase A, lysosomal acid, cholesterol esterase [Source:NCBI gene;Acc:548564]) HSP 1 Score: 309.301 bits (791), Expect = 3.487e-101 Identity = 155/370 (41.89%), Postives = 227/370 (61.35%), Query Frame = 2
Query: 332 PEVTMDV-NEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
P+ M +E+I+Y GYP E ++V TEDGYIL++ RIP+G + KPVVFLQHGLL WV N SL FILAD G+DVW+GNSRGNT+SRKH SP + FW F++DE+A+ DLPA +++ + +++ Y+GHSQGT I F FS L K+ + LAPV + K+ + + L + +I GEFLP L+ ++ C + CGN+ FLL G+N +NLN +R+ +Y +H PAGTS +N+ H+ Q S + + FD+G N + YNQ TPP Y + +P A++ GGNDW+A ++DV + ++ N+ K IP++ H+DFIWG +A R+Y ++I + K+
Sbjct: 2 PDCRMHCPSELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEEFWAFSYDELAKKDLPAVVDFITKKTGQEQIFYVGHSQGTTIAFIAFSSLPQLAKKIKMYFGLAPVATVKFSKSPLAKLGVLPEF--LIEELFGKGEFLPQTYLITWLATHFCTHAIADELCGNIFFLLSGFNEKNLNMSRVNVYSSHCPAGTSVQNMLHWRQGVRSGELKAFDFGTKGNMIHYNQTTPPFYHVRDMTVPTALWTGGNDWLADRKDVALLLTQV-SNLVYHKEIPDWEHLDFIWGLDAPERMYNEIIAMMKKF 368
BLAST of Lipase vs. Ensembl Xenopus
Match: lipa (lipase A, lysosomal acid, cholesterol esterase [Source:NCBI gene;Acc:548564]) HSP 1 Score: 308.916 bits (790), Expect = 4.342e-101 Identity = 153/362 (42.27%), Postives = 224/362 (61.88%), Query Frame = 2
Query: 353 NEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
+E+I+Y GYP E ++V TEDGYIL++ RIP+G + KPVVFLQHGLL WV N SL FILAD G+DVW+GNSRGNT+SRKH SP + FW F++DE+A+ DLPA +++ + +++ Y+GHSQGT I F FS L K+ + LAPV + K+ + + L + +I GEFLP L+ ++ C + CGN+ FLL G+N +NLN +R+ +Y +H PAGTS +N+ H+ Q S + + FD+G N + YNQ TPP Y + +P A++ GGNDW+A ++DV + ++ N+ K IP++ H+DFIWG +A R+Y ++I + K+
Sbjct: 2 DELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEEFWAFSYDELAKKDLPAVVDFITKKTGQEQIFYVGHSQGTTIAFIAFSSLPQLAKKIKMYFGLAPVATVKFSKSPLAKLGVLPEF--LIEELFGKGEFLPQTYLITWLATHFCTHAIADELCGNIFFLLSGFNEKNLNMSRVNVYSSHCPAGTSVQNMLHWRQGVRSGELKAFDFGTKGNMIHYNQTTPPFYHVRDMTVPTALWTGGNDWLADRKDVALLLTQV-SNLVYHKEIPDWEHLDFIWGLDAPERMYNEIIAMMKKF 360
BLAST of Lipase vs. Ensembl Xenopus
Match: lipa (lipase A, lysosomal acid, cholesterol esterase [Source:NCBI gene;Acc:548564]) HSP 1 Score: 308.531 bits (789), Expect = 9.514e-101 Identity = 153/361 (42.38%), Postives = 223/361 (61.77%), Query Frame = 2
Query: 356 EVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
E+I+Y GYP E ++V TEDGYIL++ RIP+G + KPVVFLQHGLL WV N SL FILAD G+DVW+GNSRGNT+SRKH SP + FW F++DE+A+ DLPA +++ + +++ Y+GHSQGT I F FS L K+ + LAPV + K+ + + L + +I GEFLP L+ ++ C + CGN+ FLL G+N +NLN +R+ +Y +H PAGTS +N+ H+ Q S + + FD+G N + YNQ TPP Y + +P A++ GGNDW+A ++DV + ++ N+ K IP++ H+DFIWG +A R+Y ++I + K+
Sbjct: 13 ELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEEFWAFSYDELAKKDLPAVVDFITKKTGQEQIFYVGHSQGTTIAFIAFSSLPQLAKKIKMYFGLAPVATVKFSKSPLAKLGVLPEF--LIEELFGKGEFLPQTYLITWLATHFCTHAIADELCGNIFFLLSGFNEKNLNMSRVNVYSSHCPAGTSVQNMLHWRQGVRSGELKAFDFGTKGNMIHYNQTTPPFYHVRDMTVPTALWTGGNDWLADRKDVALLLTQV-SNLVYHKEIPDWEHLDFIWGLDAPERMYNEIIAMMKKF 370
BLAST of Lipase vs. Ensembl Xenopus
Match: lipa (lipase A, lysosomal acid, cholesterol esterase [Source:NCBI gene;Acc:548564]) HSP 1 Score: 308.531 bits (789), Expect = 1.522e-100 Identity = 153/367 (41.69%), Postives = 226/367 (61.58%), Query Frame = 2
Query: 338 VTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
+ + +E+I+Y GYP E ++V TEDGYIL++ RIP+G + KPVVFLQHGLL WV N SL FILAD G+DVW+GNSRGNT+SRKH SP + FW F++DE+A+ DLPA +++ + +++ Y+GHSQGT I F FS L K+ + LAPV + K+ + + L + +I GEFLP L+ ++ C + CGN+ FLL G+N +NLN +R+ +Y +H PAGTS +N+ H+ Q S + + FD+G N + YNQ TPP Y + +P A++ GGNDW+A ++DV + ++ N+ K IP++ H+DFIWG +A R+Y ++I + K+
Sbjct: 28 LIISSSELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEEFWAFSYDELAKKDLPAVVDFITKKTGQEQIFYVGHSQGTTIAFIAFSSLPQLAKKIKMYFGLAPVATVKFSKSPLAKLGVLPEF--LIEELFGKGEFLPQTYLITWLATHFCTHAIADELCGNIFFLLSGFNEKNLNMSRVNVYSSHCPAGTSVQNMLHWRQGVRSGELKAFDFGTKGNMIHYNQTTPPFYHVRDMTVPTALWTGGNDWLADRKDVALLLTQV-SNLVYHKEIPDWEHLDFIWGLDAPERMYNEIIAMMKKF 391
BLAST of Lipase vs. Ensembl Mouse
Match: Lipa (lysosomal acid lipase A [Source:MGI Symbol;Acc:MGI:96789]) HSP 1 Score: 316.235 bits (809), Expect = 1.634e-103 Identity = 169/376 (44.95%), Postives = 226/376 (60.11%), Query Frame = 2
Query: 326 TDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGI-KKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFV-INKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLI--KFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYN 1441
DPEV M+V E+I +GYP E H V T DGYIL++ RIP GR + G +PVV+LQHGLL S WV N SL F+LAD GFDVW+GNSRGNT+S KH S FW F++DEMA++DLPASINY L + +++ Y+GHSQG IGF FSQ +L K+ F+ LAPV+ L + + L D ++ +FLP ++ +S VC + C NV FLL G+N +NLN +R+ +Y TH PAGTS +N+ H+ Q K Q FD+G N YNQ PP Y + LP A++ GG DW+A D+N L Q KL+ K IPE++H+DFIWG +A ++Y ++I + KY
Sbjct: 27 VDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGLLADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEMAKYDLPASINYILNKTGQEQIYYVGHSQGCTIGFIAFSQMPELAKKIKMFLVLAPVLSLNFASGPLLQLGRLPDP--LLKDMFGQKQFLPQSAMLKWLSIHVCTHVIMKELCANVFFLLCGFNEKNLNMSRVDVYTTHCPAGTSVQNMLHWGQVFKYRKLQAFDWGSSEKNYFHYNQSFPPSYNIKNMRLPTALWSGGRDWLA---DINDITILLTQIPKLVYHKNIPEWDHLDFIWGLDAPWKLYDEIISLMKKYQ 397
BLAST of Lipase vs. Ensembl Mouse
Match: Lipa (lysosomal acid lipase A [Source:MGI Symbol;Acc:MGI:96789]) HSP 1 Score: 316.235 bits (809), Expect = 1.634e-103 Identity = 169/376 (44.95%), Postives = 226/376 (60.11%), Query Frame = 2
Query: 326 TDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGI-KKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFV-INKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLI--KFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYN 1441
DPEV M+V E+I +GYP E H V T DGYIL++ RIP GR + G +PVV+LQHGLL S WV N SL F+LAD GFDVW+GNSRGNT+S KH S FW F++DEMA++DLPASINY L + +++ Y+GHSQG IGF FSQ +L K+ F+ LAPV+ L + + L D ++ +FLP ++ +S VC + C NV FLL G+N +NLN +R+ +Y TH PAGTS +N+ H+ Q K Q FD+G N YNQ PP Y + LP A++ GG DW+A D+N L Q KL+ K IPE++H+DFIWG +A ++Y ++I + KY
Sbjct: 27 VDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGLLADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEMAKYDLPASINYILNKTGQEQIYYVGHSQGCTIGFIAFSQMPELAKKIKMFLVLAPVLSLNFASGPLLQLGRLPDP--LLKDMFGQKQFLPQSAMLKWLSIHVCTHVIMKELCANVFFLLCGFNEKNLNMSRVDVYTTHCPAGTSVQNMLHWGQVFKYRKLQAFDWGSSEKNYFHYNQSFPPSYNIKNMRLPTALWSGGRDWLA---DINDITILLTQIPKLVYHKNIPEWDHLDFIWGLDAPWKLYDEIISLMKKYQ 397
BLAST of Lipase vs. Ensembl Mouse
Match: Lipm (lipase, family member M [Source:MGI Symbol;Acc:MGI:1926003]) HSP 1 Score: 313.923 bits (803), Expect = 2.543e-102 Identity = 171/401 (42.64%), Postives = 240/401 (59.85%), Query Frame = 2
Query: 263 IRVPCLLIVSINGGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTS-SPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVI---MRTVTTG--EFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGF-VINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYNN 1444
I V LL ++N G L P DPE M+V+E+IK+ GYP E ++V TEDGYIL++ RIP G+T +PVV LQHGLL + W++N P SL FILAD GFDVW+GNSRGNT+SRKH S FW F++DEMA+FDLPA IN+ L + K+ Y+G+SQGT +GF FS +L K+ + ALAP+ +KY G F ++ M V G EFL + + ++CG + C N+ LL G+N N+N +R +YV H PAGTS +NI H++Q+ S + + FD+G N+ K NQ TP +Y + +P AM+ GG DW++ +DV + E+ N+ K IPE+ H+DFIWG +A R+Y ++I + + N
Sbjct: 21 ILVAYLLQRNVNSGHL-PTKAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQTRLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQKKVYYVGYSQGTTMGFIAFSTMPELAHKIKMYFALAPI-------ATVKYARSPGTKFLLLPDMMIKVLFGRQEFLYQTRFFRQLFIYLCGQMILDQICSNIILLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNQEKCNQPTPIRYKVRDMMVPTAMWTGGQDWLSNPDDVKTLLSEV-TNLIYHKNIPEWAHVDFIWGLDAPQRVYNEIIHLMKQEPN 412
BLAST of Lipase vs. Ensembl Mouse
Match: Lipf (lipase, gastric [Source:MGI Symbol;Acc:MGI:1914967]) HSP 1 Score: 301.212 bits (770), Expect = 1.016e-97 Identity = 156/370 (42.16%), Postives = 238/370 (64.32%), Query Frame = 2
Query: 329 DPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGI-KKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGE-FLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVI-NKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFL 1429
+PE M+V+++I Y+GYP E ++V TEDGYIL + RIPYG+ +S I K+PV +LQHGL+ S+ W+ N P SLAFILAD G+DVWLGNSRGNT+SRK+ +SP S FW F++DEMA++DLPA+I++ + + +K+ Y+GHSQGT IGF FS L K+ F ALAPV + ++ K I+ + +++ + + F+P+ L + VC ++ L C N F+ G++ +NLN +R +Y+ H PAGTS++++ H+AQ S K Q +++G + N L YNQ TPP Y + +P+A++ GG+D +A +DV + +L N+ K I YNH+DFIW +A +Y +++ +
Sbjct: 27 NPEANMNVSQMITYWGYPSEEYEVVTEDGYILGVYRIPYGKKNSENIGKRPVAYLQHGLIASATNWITNLPNNSLAFILADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATIDFIVQKTGQEKIHYVGHSQGTTIGFIAFSTNPALAKKIKRFYALAPVATVKYTESPFKKISLIP---KFLLKVIFGNKMFMPHNYLDQFLGTEVCSRELLDLLCSNALFIFCGFDKKNLNVSRFDVYLGHNPAGTSTQDLFHWAQLAKSGKLQAYNWGSPLQNMLHYNQKTPPYYDVSAMTVPIAVWNGGHDILADPQDVAMLLPKL-PNLLYHKEILPYNHLDFIWAMDAPQEVYNEIVTMM 392
BLAST of Lipase vs. Ensembl Mouse
Match: Lipk (lipase, family member K [Source:MGI Symbol;Acc:MGI:2679259]) HSP 1 Score: 296.975 bits (759), Expect = 5.009e-96 Identity = 158/387 (40.83%), Postives = 228/387 (58.91%), Query Frame = 2
Query: 275 CLLIVSINGGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGR-TSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFV-INKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFL 1429
C+L+ G I T+PE M+++E+I Y+GYP E H V TEDGYIL RIP+G+ S K VV+LQHGL+ S+ W+ N P SLAF+LAD G+DVWLGNSRGNT+SR H + SP S +W F+WDEMA++DLPA++N L S +L Y+GHSQGT I F FS +L K+ F ALAPV + ++ +K + L + F + ++ VC ++ C N F L G++ +NLN +R+ +Y++ PAGTS +N+ H+AQ+ S + Q FD+G N + +NQ+TPP Y + +P AM+ GG D +A +D + ++ N+ K IP YNH+DF G +A +Y D+I +
Sbjct: 10 CVLLSGPIDGYKQESI-TNPEANMNISELISYWGYPYEKHDVITEDGYILGTYRIPHGKGCSRKTAPKAVVYLQHGLIASANNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRNHLRLSPKSPQYWAFSWDEMAKYDLPATVNLILEKSGQKQLFYVGHSQGTTIAFIAFSTNPELAKKIRLFFALAPVATVKYTRSPMKKLTTLSR--KAVKVLFGDKMFSTHTWFEQFIATKVCNRKLFHQLCSNFLFSLSGFDPQNLNMSRLDVYLSQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMRVPTAMWSGGQDVVADAKDTKNLLPKIA-NLIYYKEIPHYNHMDFYLGQDAPQEVYGDLIRMI 392
BLAST of Lipase vs. UniProt/SwissProt
Match: sp|P38571|LICH_HUMAN (Lysosomal acid lipase/cholesteryl ester hydrolase OS=Homo sapiens OX=9606 GN=LIPA PE=1 SV=2) HSP 1 Score: 328.946 bits (842), Expect = 1.248e-107 Identity = 175/397 (44.08%), Postives = 243/397 (61.21%), Query Frame = 2
Query: 269 VPCLLIVSIN----GGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTS-SPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYG-FVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYN 1441
V CL++ +++ GG L+ DPE M+V+E+I Y+G+P E + V TEDGYIL + RIP+GR + S KPVVFLQHGLL S WV N SL FILAD GFDVW+GNSRGNT+SRKH S FW F++DEMA++DLPASIN+ L + +++ Y+GHSQGT IGF FSQ +L ++ F AL PV + + + + L D ++I EFLP + + VC + CGN+ FLL G+N NLN +R+ +Y TH PAGTS +N+ H++Q+ KFQ FD+G N YNQ PP Y + +P A++ GG+DW+A DVN + ++ N+ + IPE+ H+DFIWG +A R+Y +I+ + KY
Sbjct: 9 VVCLVLWTLHSEGSGGKLTA---VDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPD--HLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQI-TNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ 399
BLAST of Lipase vs. UniProt/SwissProt
Match: sp|Q4R4S5|LICH_MACFA (Lysosomal acid lipase/cholesteryl ester hydrolase OS=Macaca fascicularis OX=9541 GN=LIPA PE=2 SV=1) HSP 1 Score: 327.791 bits (839), Expect = 2.997e-107 Identity = 175/396 (44.19%), Postives = 244/396 (61.62%), Query Frame = 2
Query: 269 VPCLLIVSIN----GGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTS-SPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYG-FVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
V CL++ +++ GG L+ +PE M+V+E+I Y+G+P E + V TEDGYIL + RIP+GR + S KPVVFLQHGLL S WV N SL FILAD GFDVW+GNSRGNT+SRKH S FW F++DEMA++DLPASIN+ L + +++ Y+GHSQGT IGF FSQ +L ++ F ALAPVV + + + + L D +I EFLP + + VC + CGN+ FLL G+N NLN +R+ +Y TH PAGTS +N+ H++Q+ KFQ FD+G N YNQ PP Y + +P A++ GG+DW+A D+N + ++ N+ + IPE+ H+DFIWG +A R+Y +I+ + KY
Sbjct: 9 VVCLVLWTLHSEASGGKLTA---VNPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALAPVVSVDFCTSPMAKLGRLPDL--LIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDINILLTQI-TNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMKKY 398
BLAST of Lipase vs. UniProt/SwissProt
Match: sp|P80035|LIPG_CANLF (Gastric triacylglycerol lipase OS=Canis lupus familiaris OX=9615 GN=LIPF PE=1 SV=2) HSP 1 Score: 317.775 bits (813), Expect = 2.601e-103 Identity = 166/383 (43.34%), Postives = 243/383 (63.45%), Query Frame = 2
Query: 302 GLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGI-KKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVI---MRTVTTGE--FLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGF-VINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFL 1429
GL T+PEVTM+++++I Y+GYP E ++V TEDGYIL + RIPYGR +S I ++PV FLQHGLL S+ W++N P SLAFILAD G+DVWLGNSRGNT++R++ +SP S FW F++DEMA++DLPA+I++ L + DKL Y+GHSQGT IGF FS L ++ F ALAPV +KY L + ++ + + G F P+ ++ VC + L C N F++ G++ NLN +R+ +Y++H PAGTS +N+ H++Q+ S KFQ FD+G V N + Y+Q PP Y L +P+A++ GGND +A DV+ + +L N+ + IP YNH+DFIW +A +Y +++ +
Sbjct: 19 GLFGKLHPTNPEVTMNISQMITYWGYPAEEYEVVTEDGYILGIDRIPYGRKNSENIGRRPVAFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFILKKTGQDKLHYVGHSQGTTIGFIAFSTNPKLAKRIKTFYALAPVA-------TVKYTETLLNKLMLVPSFLFKLIFGNKIFYPHHFFDQFLATEVCSRETVDLLCSNALFIICGFDTMNLNMSRLDVYLSHNPAGTSVQNVLHWSQAVKSGKFQAFDWGSPVQNMMHYHQSMPPYYNLTDMHVPIAVWNGGNDLLADPHDVDLLLSKL-PNLIYHRKIPPYNHLDFIWAMDAPQAVYNEIVSMM 393
BLAST of Lipase vs. UniProt/SwissProt
Match: sp|Q9Z0M5|LICH_MOUSE (Lysosomal acid lipase/cholesteryl ester hydrolase OS=Mus musculus OX=10090 GN=Lipa PE=1 SV=2) HSP 1 Score: 316.235 bits (809), Expect = 1.143e-102 Identity = 169/376 (44.95%), Postives = 226/376 (60.11%), Query Frame = 2
Query: 326 TDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGI-KKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFV-INKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLI--KFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYN 1441
DPEV M+V E+I +GYP E H V T DGYIL++ RIP GR + G +PVV+LQHGLL S WV N SL F+LAD GFDVW+GNSRGNT+S KH S FW F++DEMA++DLPASINY L + +++ Y+GHSQG IGF FSQ +L K+ F+ LAPV+ L + + L D ++ +FLP ++ +S VC + C NV FLL G+N +NLN +R+ +Y TH PAGTS +N+ H+ Q K Q FD+G N YNQ PP Y + LP A++ GG DW+A D+N L Q KL+ K IPE++H+DFIWG +A ++Y ++I + KY
Sbjct: 27 VDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGLLADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEMAKYDLPASINYILNKTGQEQIYYVGHSQGCTIGFIAFSQMPELAKKIKMFLVLAPVLSLNFASGPLLQLGRLPDP--LLKDMFGQKQFLPQSAMLKWLSIHVCTHVIMKELCANVFFLLCGFNEKNLNMSRVDVYTTHCPAGTSVQNMLHWGQVFKYRKLQAFDWGSSEKNYFHYNQSFPPSYNIKNMRLPTALWSGGRDWLA---DINDITILLTQIPKLVYHKNIPEWDHLDFIWGLDAPWKLYDEIISLMKKYQ 397
BLAST of Lipase vs. UniProt/SwissProt
Match: sp|Q8K2A6|LIPM_MOUSE (Lipase member M OS=Mus musculus OX=10090 GN=Lipm PE=2 SV=1) HSP 1 Score: 313.923 bits (803), Expect = 1.779e-101 Identity = 171/401 (42.64%), Postives = 240/401 (59.85%), Query Frame = 2
Query: 263 IRVPCLLIVSINGGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTS-SPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVI---MRTVTTG--EFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGF-VINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYNN 1444
I V LL ++N G L P DPE M+V+E+IK+ GYP E ++V TEDGYIL++ RIP G+T +PVV LQHGLL + W++N P SL FILAD GFDVW+GNSRGNT+SRKH S FW F++DEMA+FDLPA IN+ L + K+ Y+G+SQGT +GF FS +L K+ + ALAP+ +KY G F ++ M V G EFL + + ++CG + C N+ LL G+N N+N +R +YV H PAGTS +NI H++Q+ S + + FD+G N+ K NQ TP +Y + +P AM+ GG DW++ +DV + E+ N+ K IPE+ H+DFIWG +A R+Y ++I + + N
Sbjct: 21 ILVAYLLQRNVNSGHL-PTKAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQTRLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQKKVYYVGYSQGTTMGFIAFSTMPELAHKIKMYFALAPI-------ATVKYARSPGTKFLLLPDMMIKVLFGRQEFLYQTRFFRQLFIYLCGQMILDQICSNIILLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNQEKCNQPTPIRYKVRDMMVPTAMWTGGQDWLSNPDDVKTLLSEV-TNLIYHKNIPEWAHVDFIWGLDAPQRVYNEIIHLMKQEPN 412
BLAST of Lipase vs. TrEMBL
Match: A0A4V3SDI7 (Lipase OS=Opisthorchis felineus OX=147828 GN=CRM22_008291 PE=3 SV=1) HSP 1 Score: 384.415 bits (986), Expect = 7.762e-127 Identity = 182/374 (48.66%), Postives = 252/374 (67.38%), Query Frame = 2
Query: 317 GIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
+ DPE+ + ++I+ YG+ +E H V T DGYIL + R+ R + + K VVFLQHGLLDS+ TW+NN +SLAFILAD GFDVWLGNSRG+TYSRKH K+ FW+F+WD+MAQFDLPAS+ + L V+ ++ LGY+GHSQG +I A+F++ +L S +S FVALAPV YLG++ + I+YIA + GEFLP+ +L++ ++ F+CG C NV +LL GY+ +N N TR+P+Y+ H PAGTS+KN+ HY Q +++FQ FDYG V N Y Q TPPKY L +P A+F GGNDW+AV++DV+R I ++ V PEYNH+DF+WG +A +YP+V+ L +Y
Sbjct: 36 SLSKDPEILENATQIIRNYGFHVEEHYVKTADGYILCLIRM---RNPNIELNKKVVFLQHGLLDSAHTWINNLRNQSLAFILADAGFDVWLGNSRGSTYSRKHEKYDTHHIEFWEFSWDQMAQFDLPASVYHVLQVTGSNTLGYVGHSQGAQIALAQFNRDPELQSHISLFVALAPVAYLGHIASPIRYIAPFARTVERVWDLFGHGEFLPSTRLLHFLAYFLCGRGHIPFVCTNVVYLLAGYDAKNTNLTRLPVYIAHTPAGTSAKNMVHYCQGITTDQFQAFDYGKVKNLEIYGQKTPPKYDLSKFTVPTAVFTGGNDWLAVEKDVDRLIEQIKPAVVSHINFPEYNHLDFVWGMDAAMVLYPEVLKLLKQY 406
BLAST of Lipase vs. TrEMBL
Match: C3V6K8 (Lipase OS=Clonorchis sinensis OX=79923 PE=2 SV=1) HSP 1 Score: 380.178 bits (975), Expect = 4.315e-125 Identity = 182/370 (49.19%), Postives = 249/370 (67.30%), Query Frame = 2
Query: 329 DPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
DPE+ + ++I+ YG+ +E H V T DGYIL + R+ R + + K VVFLQHGLLDS+ TW+NN +SLAFILAD GFDVWLGNSRG+TYSRKH K+ FW+F+WD+MAQFDLPAS+ + L VS ++ +GY+GHSQG +I A+F++ +L S +S FVALAPV YLGN+ + I+YIA + GEFL + +L++ ++ F+CG C NV +LL GY+ N N TR+P+Y+ H PAGTS+KN+ HY Q +++FQ FDYG V N Y Q TPPKY L +P A+F GGNDW+AV++DV+R I ++ V PEYNH+DF+WG +A +YP+V+ L +Y
Sbjct: 40 DPEILENATQIIRNYGFHVEEHYVKTADGYILCLIRM---RNPNIELNKKVVFLQHGLLDSAHTWINNLRNQSLAFILADAGFDVWLGNSRGSTYSRKHEKYDTHHIEFWEFSWDQMAQFDLPASLYHVLQVSGSNTVGYVGHSQGAQIALAQFNRDPELQSHISLFVALAPVAYLGNIASPIRYIAPFARTVERVWDLFGHGEFLSSTRLLHFLAYFLCGRGHIPFVCTNVVYLLAGYDARNTNLTRLPVYIAHTPAGTSAKNMVHYCQGISTDQFQAFDYGKVKNLEIYGQKTPPKYDLSKFTVPTAVFSGGNDWLAVEKDVDRLIDQIKPAVISHINFPEYNHLDFVWGMDAAIVLYPEVLRLLNQY 406
BLAST of Lipase vs. TrEMBL
Match: A0A5J4P2H5 (Lipase OS=Paragonimus westermani OX=34504 GN=DEA37_0006749 PE=3 SV=1) HSP 1 Score: 378.252 bits (970), Expect = 3.200e-124 Identity = 179/373 (47.99%), Postives = 248/373 (66.49%), Query Frame = 2
Query: 320 IETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
+ DPE+ ++ ++I YGY +E H VTT+DGYIL + R+ R + VV+LQHGLLDS+ TW+NN +SLAFILAD GFDVWLGNSRG+TYSR H +P FW+F+WD+MAQFDLP+SI Y L V+ A K+GY+GHSQG +I A+F + L S++S F+A APV +LG+LK+ I+++A L ++ GEFLP+ +L+ ++ F+C C NV +L+ GY+ EN N TR+P+YV H PAGTS++NI HY QS S++FQ+FDYG N Y Q TPP+Y L +P +F GG+DW+AVK+DV R + + + V P YNH+DF+WG + +YP V+D+L KY
Sbjct: 49 LHIDPEIKLNATQIIMSYGYHVEEHFVTTDDGYILCLFRMRNPRFLDRNDLR-VVYLQHGLLDSAHTWINNLRNESLAFILADAGFDVWLGNSRGSTYSRNHIYLTPEQLKFWEFSWDQMAQFDLPSSIYYVLNVTGAQKIGYVGHSQGCQIALAQFDRDPQLQSRISVFIAFAPVAFLGHLKSPIRFVAPLAQTLEEVLELFNKGEFLPSNKLMQFLAYFLCRRGHVPFVCTNVIYLIAGYDYENTNTTRLPVYVAHTPAGTSTQNIVHYCQSITSDRFQQFDYGIKKNLQIYGQPTPPEYDLSNITVPTVVFSGGHDWLAVKKDVLRLMDRIEKAVVSYTHFPYYNHLDFVWGMDTGYVLYPAVLDWLSKY 420
BLAST of Lipase vs. TrEMBL
Match: C3ZXQ3 (Lipase OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_131171 PE=3 SV=1) HSP 1 Score: 363.229 bits (931), Expect = 2.817e-118 Identity = 188/399 (47.12%), Postives = 254/399 (63.66%), Query Frame = 2
Query: 263 IRVPCLLIVSINGGLLSPGIE------TDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGR-TSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFV-INKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLK 1435
+ V + V + SP I+ DPEV M+ ++I GYP E + V T+DG++L +QRIPYGR +S ++P +FLQHGLL +S W+ N +SLAFILAD GFDVWLGN RGNTYSRKH K++P FWDF+WDEMA++DLPA + +AL + L Y+GHSQGT I FA SQ + KV F ALAPVV LG++ + IKY+A D + + R EFLPN ++ ++ F+C D+ C N+ FLL G++ LN TR+P+Y +H PAGTS+KN+ H+AQ SNKFQ +DYG NK +YNQ T P YP++ PVA+F+GGNDW+A DV AI L +NV I ++H+DFIWG +A T++Y +I + K
Sbjct: 9 LHVLVIFSVILTASCFSPPIKRLWSLGEDPEVHMNATQLITSKGYPCEDYTVKTDDGFLLGVQRIPYGRNATSHKDQRPAIFLQHGLLSASTDWILNLANESLAFILADAGFDVWLGNMRGNTYSRKHVKYTPDDDEFWDFSWDEMAKYDLPAMVTFALNKTGQSSLYYVGHSQGTAIAFAHLSQDQEFAKKVKTFFALAPVVTLGHITSPIKYLAQFDDIISAMFRIFGVDEFLPNSWWLDWLASFLC-DKSTEKYCENMLFLLVGFDPVQLNETRLPVYFSHTPAGTSTKNMVHFAQMVNSNKFQAYDYGNPDDNKQQYNQPTAPVYPIENMTTPVALFWGGNDWLADPTDVQAAIPHL-KNVVYNSEIKNFDHMDFIWGKDA-TKLYDQIIKIIRK 404
BLAST of Lipase vs. TrEMBL
Match: A0A3Q0KCA5 (Lipase OS=Schistosoma mansoni OX=6183 PE=3 SV=1) HSP 1 Score: 362.844 bits (930), Expect = 2.879e-118 Identity = 168/368 (45.65%), Postives = 239/368 (64.95%), Query Frame = 2
Query: 326 TDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFL 1429
DPEV ++ E+I GY E H VTTEDG+IL + RI + G +K VVFLQHGLLDS+ TWVNN PE+SL FILAD +DVWLGNSRG+TYS H P K FW+F+WDEM ++DLPA++ Y L + A+KL YIGHSQG +I A F + + S + F+ALAP YLG++K+ I+YIA ++ GEFLP+ +++ ++ F+C C N+ +LL GY+ +N N +R+PIYV H PAGTS +N+ HY Q ++++FQK+DYG + N YNQ PP Y + LP+ ++YGG DW+A D+++ I ++ ++ + P+YNH+DF+WG NA +YP +++ L
Sbjct: 42 VDPEVYQNITEIISSKGYKFEEHYVTTEDGFILCIIRILPKCNEASGRQK-VVFLQHGLLDSAHTWVNNLPEESLGFILADNCYDVWLGNSRGSTYSSNHQYLRPDDKEFWEFSWDEMGKYDLPATLMYVLNHTDAEKLSYIGHSQGCQIALACFDEHPIIQSFIDLFIALAPAAYLGSIKSPIRYIAPFVKTVEPVVEWFGNGEFLPSGKIMQFLALFLCKPHRIPFVCSNIMYLLAGYDSKNTNVSRLPIYVAHTPAGTSVQNMVHYCQGIVTDRFQKYDYGLIKNLQIYNQSYPPLYNISHLKLPIIIYYGGQDWLASYRDIHKLIKQINYTIRSTHYFPDYNHLDFVWGLNAAKLLYPLILEQL 408
BLAST of Lipase vs. Ensembl Cavefish
Match: lipf (lysosomal acid lipase/cholesteryl ester hydrolase-like [Source:NCBI gene;Acc:103040858]) HSP 1 Score: 321.627 bits (823), Expect = 8.180e-106 Identity = 161/369 (43.63%), Postives = 229/369 (62.06%), Query Frame = 2
Query: 329 DPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYG--RTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFL 1429
DPEV M+++E+I+Y+GYP E ++V TEDGYIL++ RIPYG S +PVVFLQHGLL + WV N P SL F+LAD GFDVWLGNSRGNT+SRKH SP +W+F+ DEMA DLPA IN+ + +K+ Y+GHSQGT I F FS L SK+ F ALAPV + + + ++ L +A +I +F P +L+ + C + S+ CGN+ FLL G++ NLN TR P+Y TH PAGTS +N+AH++Q+ + K +DYG N YNQ TPP+Y + +P A++ GG+D +A +DV + ++ N+ + I + H+DFIWG +A ++ ++I +
Sbjct: 27 DPEVNMNISEIIRYWGYPAEEYEVVTEDGYILSINRIPYGVKNKDSQAAPRPVVFLQHGLLAAGSNWVTNLPNTSLGFVLADAGFDVWLGNSRGNTWSRKHVSLSPDQNEYWEFSHDEMANKDLPAVINFITKTTAEEKIFYVGHSQGTTIAFMAFSTMPLLASKIKMFFALAPVATVAFTSSPMGKLSVLPEA--LIWDLFGRKDFFPQNELIKFFATEFCTKKPISVLCGNIFFLLCGFDERNLNMTRTPVYTTHCPAGTSVQNMAHWSQAVKTGKLMAYDYGKAGNMAHYNQSTPPQYHVQDMTVPTAVWSGGHDTLADPQDVAVLLTQI-PNLMYHRHIEHWEHLDFIWGLDAPQEMFGEMIKLM 392
BLAST of Lipase vs. Ensembl Cavefish
Match: lipf (lysosomal acid lipase/cholesteryl ester hydrolase-like [Source:NCBI gene;Acc:103023710]) HSP 1 Score: 292.352 bits (747), Expect = 1.787e-94 Identity = 148/371 (39.89%), Postives = 220/371 (59.30%), Query Frame = 2
Query: 323 ETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYG--RTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFL 1429
DPE+ M+++E+I+Y+GYP E ++V TEDGYIL++ RIP+G S KPVVFLQHGLL ++ WV N P SL ++LAD GFDVWLGNSRGNT+SRKH S +W F+ DE+A+ DLPA IN+ + +K+ Y+GHSQGT I F FS +L SK+ F LAPV + + I + L + +I F P L+ + C + C N+ F + G+ +NLN TR+P+Y++H PAGTS +N+ H++Q+ S K +D+G N + Y ++TP +Y + +P A++ GG D +A DV + ++ V+ + I + H+DFIWG +A +Y ++I +
Sbjct: 25 RVDPEIHMNISEIIRYWGYPAEEYEVVTEDGYILSINRIPHGIKNQDSRADPKPVVFLQHGLLAAASNWVTNLPNTSLGYLLADAGFDVWLGNSRGNTWSRKHVSLSRDQNEYWRFSRDELAKKDLPAVINFITRTTGQEKIFYVGHSQGTTIAFMAFSTMPELASKIKMFFGLAPVATIAFTTSPITKLRILPE--KLIWGLFGKKYFFPQSSLIKFFATKFCSKNPFNAFCRNIFFRIHGFERKNLNMTRVPVYISHTPAGTSVRNMVHWSQALKSGKLMAYDFGKAGNLVHYKKLTPYQYNVKDMTVPTALWSGGRDILADPLDVAMLLPQISNLVQHRR-IEHWGHMDFIWGLDAPQTLYNEIIKMM 392
BLAST of Lipase vs. Ensembl Sea Lamprey
Match: lipf (lipase, gastric [Source:ZFIN;Acc:ZDB-GENE-040426-2737]) HSP 1 Score: 301.982 bits (772), Expect = 1.215e-98 Identity = 159/415 (38.31%), Postives = 245/415 (59.04%), Query Frame = 2
Query: 221 LSYV*IREINTVAYIRVPCLLI-VSINGGLLSPG----IETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYG-RTSSPGIK-KPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTV-TTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFV-INKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
L +V IR + + + V LL V G + P + +DPE+ M+++E+I GYP ++V T DG+IL++ RIP G + ++ G +P V LQHGLL WV+N SL FILAD G+DVW+GNSRGNT+S H +P + FW +++DEMA DLPA +++ L +K ++L Y+GHSQGT A FS L K+ F+ LA VV N+ + +A L D + ++ + EFLP ++ +S VC + C NV F++ G+N +N+N +R+P+Y +H PAGTS +N+ H+ Q+ S +FQ +DYG + +N YNQ TPP Y + +P A++ GG DW+A D + ++ N+ K + ++ H+DFIWG +A R++PD++ + KY
Sbjct: 1 LCFVLIRNMVLIVALHVTLLLFGVGFVSGRMLPDQHNDLRSDPEIYMNISELISSKGYPNVEYKVETADGFILSVNRIPRGLKDNTAGTAVRPAVLLQHGLLAGGSNWVSNFAHDSLGFILADAGYDVWIGNSRGNTWSHHHRTLTPDQEEFWAWSYDEMASLDLPAVVDFILNETKQERLFYVGHSQGTTTALAAFSSNPKLAKKIKLFIGLAAVV---NVHHSTSPMAKLADVPDWLIEAIFGKKEFLPQNDILKWLSAEVCDKAIIKDLCENVFFVICGFNEKNMNVSRVPVYTSHCPAGTSIQNMLHWRQAARSGRFQAYDYGSLWLNMKHYNQATPPAYNISAMTVPTALWSGGQDWLADPTDTAALLAKI-PNLVQHKVLKDWEHLDFIWGMDAPKRLFPDMLKLMEKY 411
BLAST of Lipase vs. Ensembl Sea Lamprey
Match: lipf (lipase, gastric [Source:ZFIN;Acc:ZDB-GENE-040426-2737]) HSP 1 Score: 197.208 bits (500), Expect = 5.498e-60 Identity = 110/290 (37.93%), Postives = 168/290 (57.93%), Query Frame = 2
Query: 275 CLLIVSINGGLLSP--GIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQ 1138
C ++VS+ LL + +DPE+ M+++E+I GYP ++V T DG+IL++ RIP G S +P V LQHGLL WV+N SL FILAD G+DVW+GNSRGNT S H +P + FW ++ DLPA +++ L ++ ++L Y GHSQ T I A FS L K+ F+ LA VV N+ + +A L D + +M+ FLP+ ++ +S + ++ C +V F++ G+N +N+N +R+P+Y +H PAGTS +N+ H+ Q
Sbjct: 2 CNILVSVILCLLQVHNDLRSDPEMYMNISELISSKGYPNVEYKVETADGFILSVNRIPRGLKHSTAAVRPAVLLQHGLLAGGSNWVSNFAHDSLGFILADAGYDVWIGNSRGNT-SHHHRALTPDQEEFWAWS-----SLDLPAVVDFILNETE-ERLFYAGHSQRTTIALAAFSSNPKLAKKIKLFIGLAAVV---NVHHSTSPMAKLADVPDWLMK------FLPHNDILKWLSAEISDKEIIEDLCEHVFFVICGFNEKNMNVSRVPVYASHCPAGTSIQNMLHWRQ 275
BLAST of Lipase vs. Ensembl Yeast
Match: TGL1 (Steryl ester hydrolase; one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes [Source:SGD;Acc:S000001623]) HSP 1 Score: 167.933 bits (424), Expect = 1.727e-46 Identity = 127/378 (33.60%), Postives = 184/378 (48.68%), Query Frame = 2
Query: 350 VNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNN-GPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAI-KYIAGLGDAF-------NVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPP----KYPLDTH-GLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYN 1441
++E+ + +E H V TED YILT+ RIP S VV+L HGLL S W N K+L F+L D G+DVW+GN+RGN YS H P S FWDF+ DE A FD+P SI + L ++K DK+ IG SQG+ FA FS LN KVS F+A+AP + L I +A F +++ + + + L N +C D + F + +N+ L ++ Y + + TS K+I H+ Q S KFQ F+ N L N +T P +P T+ +P+ + YGG D + D++ L N + Y H+D IWG +A T + V+ F+ +N
Sbjct: 66 IHEMCAIFDISVEDHLVRTEDNYILTLHRIP--PISKNRFNNKVVYLHHGLLMCSDVWCCNIERHKNLPFVLHDLGYDVWMGNNRGNKYSTAHLNKPPKSNKFWDFSIDEFAFFDIPNSIEFILDITKVDKVICIGFSQGSAQMFAAFSLSEKLNRKVSHFIAIAPAMTPKGLHNRIVDTLAKSSPGFMYLFFGRKIVLPSAVIWQRTLHPTLFN-----LCID-----IANKILFNWKSFNI--LPRQKIASYAK-LYSTTSVKSIVHWFQILRSQKFQMFEES--DNML--NSLTRPYQIANFPTRTNIKIPILLIYGGIDSLV---DIDVMKKNLPFNSVFDVKVDNYEHLDLIWGKDADTLVIAKVLRFIEFFN 421
BLAST of Lipase vs. Ensembl Yeast
Match: YEH1 (Steryl ester hydrolase; one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes; YEH1 has a paralog, YEH2, that arose from the whole genome duplication [Source:SGD;Acc:S000003935]) HSP 1 Score: 108.997 bits (271), Expect = 7.166e-26 Identity = 105/392 (26.79%), Postives = 166/392 (42.35%), Query Frame = 2
Query: 287 VSINGGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTM-QRIP-YGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFA------KF------SQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAM---SKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLP-VAMFYGGNDWMAVKEDVNRAIGELGQNVKL-IKFIPEYNHIDFIWGANAYTRI 1405
V + L + + D + D+N Y +E ++ TEDG+++ + IP Y T S K+P + + HGLL SS ++ +NG KSLA+ L G+D+WLGN+R + P WD+ EM ++DL I+ L ++ +KL I HSQGT GF KF S+ S SK++ ++ALAP VY G L ++ ++ + + F M G+ + S C + L +N + + P S K Q LS K + F +K+ + + K+ D P + +F D + E + + NV I +I EY HID +W + RI
Sbjct: 157 VQCDNPLQNLILSEDLTLVADLNYYFNQYNIQIEEFRLETEDGFVIDLWHLIPKYRTTDSDKKKRPPILMLHGLLQSSGSFASNG-RKSLAYFLYQSGYDIWLGNNRCGFRPEWNEAKVPTLASRWDWDLREMVKYDLTLLIDTVLAKTQFEKLTLISHSQGTTQGFMGLVNEDKFFPPGSGSKESFFTSKIANYIALAPAVYPGPLLNEKLFV-------KLMTKEIENPWFFGETSFFEIMMIVRNLCVGESLFSFVCYTIFNYLFDWNDTLWDTALRDRHFLFSPVHVSVK----LMQWWLSPDPNKVSFKFGSHKMFPDNV---KWFSDASKAPNIYLFVPKQDRLVDGERLINHFVNVESNVNYKIWYIDEYAHIDVLWAHDVIERI 533
BLAST of Lipase vs. Ensembl Yeast
Match: YEH2 (Steryl ester hydrolase; catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism; YEH2 has a paralog, YEH1, that arose from the whole genome duplication [Source:SGD;Acc:S000004010]) HSP 1 Score: 104.76 bits (260), Expect = 1.526e-24 Identity = 119/427 (27.87%), Postives = 182/427 (42.62%), Query Frame = 2
Query: 317 GIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTM----QRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSR------------GNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKF--------SQFSDLNSKVSAFVALAPVVYLGNL---KTAIKYIA-GLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYN-------VENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYG-----------FVI--------NKLKYNQITPPKYPLDTHGLP-VAMFYGGNDWMAVKED-VNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFL 1429
+ D ++ D+ K YG +E +V T+DG+I+ + R+ G +K+ + L HGLL S + ++G KSLA+ L + GFDVWLGN+R GN +S+K WD+ +M Q+DL A INY L + KL + HSQGT GF S F L K+ FVALAP VY G L K ++ +A G+ + R+ F+P L+ M K + G ++ S + L +N + + N+ P+++ S + + S L NK F G F I N L N++ ++ P + MF D + E +N I V I +I EY+H+D +W + RI +I+ L
Sbjct: 139 ALAEDTKLVPDLKYYYKEYGIDIEEFEVETDDGFIIDLWHFKSRLNDGVEE---VKREPILLLHGLLQSCGAFASSG-RKSLAYFLYESGFDVWLGNNRCGLNAKWNMKKLGNDHSKK-----------WDWDMHQMVQYDLKALINYVLDSTGYAKLSLVAHSQGTTQGFMGLVNGEKLYASDFK-LVDKLENFVALAPAVYPGPLLDEKAFVRLMAKGIDSPWYFGRRS-----FIP---LMMTMRKLMVGTKIFSFLSYIMFNYLFDWNDVLWDRVLRDRNFLFSPVHI--------SVKLMQWWLSPLPNKLS-FKKGAEKIFPDKKTWFPIAKNDDDSGNNLDNNKLHLNPKRQNSEEFPHIIMFIPKQDRLVDGERLINHFINHEANAVYKIWYIDEYSHLDVLWAHDVIDRIGKPMIENL 532
BLAST of Lipase vs. Ensembl Nematostella
Match: EDO35549 (Lipase [Source:UniProtKB/TrEMBL;Acc:A7SL62]) HSP 1 Score: 332.028 bits (850), Expect = 5.668e-110 Identity = 168/366 (45.90%), Postives = 233/366 (63.66%), Query Frame = 2
Query: 332 PEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRT-SSPGIK-KPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFV-INKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVI 1420
PEV M+V ++I+Y GYP+E + VTTEDGYIL++QRIPYGR G+K KPVVFLQHGLL S+ WV N +S FILAD+ FDVWLGN RGNTY ++H K S FWDF++DEMA++DLPA I++ + L Y GHSQGT IGF F+ + KV AF ALAPV + ++ A+KY+A L + + + +FLP ++ ++ VC + C + FL+ G + LN TR+PIY++H PAGTS KN+ H+AQ KFQ +DYG NK KYNQ TPP+Y + +P A+++GG+D +A DV + +L + K++P ++H+DFIW +A + +Y DVI
Sbjct: 45 PEVHMNVTQLIQYNGYPVEDYDVTTEDGYILSVQRIPYGREGKCKGVKDKPVVFLQHGLLCSATNWVTNLYNESFGFILADQCFDVWLGNVRGNTYGKRHVKLPVDSDAFWDFSFDEMAKYDLPAMIDFVTKTTGQASLYYAGHSQGTMIGFIAFAHNPAVIQKVKAFYALAPVSTVSHMGGALKYLAYLSPEIEFLFKVLGVRDFLPTDDVMRVLADLVCRPDYIRVVCSDFLFLIAGMDRSQLNETRLPIYISHTPAGTSVKNVVHFAQIFREKKFQMYDYGSAEKNKHKYNQDTPPQYNVSAVKVPSALYWGGHDVLADPTDVKDLLAKLPHQM-YNKYLPTWDHLDFIWALDAASLVYDDVI 409
BLAST of Lipase vs. Ensembl Nematostella
Match: EDO29518 (Lipase [Source:UniProtKB/TrEMBL;Acc:A7T3E6]) HSP 1 Score: 328.946 bits (842), Expect = 4.457e-109 Identity = 167/366 (45.63%), Postives = 230/366 (62.84%), Query Frame = 2
Query: 332 PEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRT-SSPGIK-KPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFV-INKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVI 1420
PE M ++I+Y GYP+E + VTTEDGYIL++QRIPYGR G+K KPVVFLQHGLL S+ WV N +S FILAD+ FDVWLGN RGNTY ++H K S FWDF++DEMA++DLPA I++ + L Y GHSQGT IGF F+ + KV AF ALAPV + ++ A+KY+A L + + + +FLP L+ ++ VC + C + FL+ G + LN TR+PIY++H PAGTS KN+ H+AQ KFQ +DYG NK KYNQ TPP+Y + +P A+++GG+D +A DV + +L + K++P ++H+DFIW +A + +Y DVI
Sbjct: 17 PETNMIFTQLIQYNGYPVEDYDVTTEDGYILSVQRIPYGREGKCKGVKDKPVVFLQHGLLCSATNWVTNLYNESFGFILADQCFDVWLGNVRGNTYGKRHVKLPVDSDAFWDFSFDEMAKYDLPAMIDFVTKTTGQASLYYAGHSQGTMIGFIAFAHNPAVIQKVKAFYALAPVSTVSHMGGALKYLAYLSPEIEFLFKVLGVRDFLPTDDLMRVLADLVCRPDYIRVVCSDFLFLIAGMDRSQLNETRLPIYISHTPAGTSVKNVVHFAQIFREKKFQMYDYGSAEKNKHKYNQDTPPQYNVSAVKVPSALYWGGHDVLADPTDVKDLLAKLPHQM-YNKYLPTWDHLDFIWALDAASLVYDDVI 381
BLAST of Lipase vs. Ensembl Nematostella
Match: EDO41646 (Lipase [Source:UniProtKB/TrEMBL;Acc:A7S3Q1]) HSP 1 Score: 323.168 bits (827), Expect = 4.687e-107 Identity = 161/374 (43.05%), Postives = 234/374 (62.57%), Query Frame = 2
Query: 323 ETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPG--IKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLI-KFIPEYNHIDFIWGANAYTRIYPDVIDFLLK 1435
DPE+ M+V+++I+Y+GYP+E + V T+DGYI+++QRIP+G+ KPV+F+QHGLL SS WV N P +SLAFILAD FDVWLGN RGN Y +H S S FWDF+WDE +++DL A I+ AL VS L Y GHSQGT + FA+ S DL SK+ A AL PV +G++++ IKY+A + + +FLPN +++ ++ C C +V F+L G++ LN TR+P+Y++H PAGTS KN+ HYAQ + S KF+ +DYG N +Y Q TPP+Y + +P +++GGNDW+A +DV+ + L + K + + H+DFIWG +A +Y D++ + K
Sbjct: 3 REDPEINMNVSQMIQYHGYPVENYDVITKDGYIISIQRIPFGQNGKCKDVPNKPVIFVQHGLLCSSTNWVANLPNESLAFILADNCFDVWLGNVRGNIYGMRHVNVSIHSDAFWDFSWDEFSKYDLTAMIDKALKVSNVSSLYYAGHSQGTMMMFAESSCNKDLASKIKAHFALGPVTTIGHIESPIKYLANFVPEVEDLFKIFGIHDFLPNNEIMRILAVLFCEPLGIRDVCSDVIFILDGFDQSQLNMTRLPVYISHTPAGTSVKNMIHYAQMYKSKKFEMYDYG-KDNIKRYGQNTPPQYNISAITVPTMLYWGGNDWLADPDDVSLLMKALPPKTLIDNKELKAWQHLDFIWGLDAAELVYDDIVTRIKK 375
BLAST of Lipase vs. Ensembl Nematostella
Match: EDO40744 (Lipase [Source:UniProtKB/TrEMBL;Acc:A7S6G4]) HSP 1 Score: 289.271 bits (739), Expect = 3.489e-93 Identity = 157/375 (41.87%), Postives = 220/375 (58.67%), Query Frame = 2
Query: 329 DPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTS--SPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKF-VCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELG---QNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLK 1435
DP++ + +++I+ GYP+E H VTT DG+IL +QRIP+GR +KPVVFLQHGLL S WV N P SL +ILAD+GFDVWLGN RGN YS H K++ S FWD+TW +MAQ+DLPA I+Y + ++ Y+GHSQGT IGF FS +L K+ F ALAPV + ++ IK A I + + EF+P+ +L MS VC C L G++ NLN +R+P+ ++H +GTS KN+ H+ Q S K QK++YG+ N +KY QI PP Y + +P +F G +D +A DV GEL QN+ + IP +NH DF++G +A +Y ++ + K
Sbjct: 31 DPDIDRNASQLIRNRGYPVEEHYVTTSDGFILNLQRIPHGRNELREGSGRKPVVFLQHGLLMDSTNWVLNSPHDSLGYILADKGFDVWLGNIRGNEYSAAHVKWNKDSSKFWDWTWQQMAQYDLPAMIDYVTLATSQSQVFYVGHSQGTLIGFTGFSANQELAKKIKMFFALAPVYTVAHVSEFIKASAYALFPVTHIFQNHVSEEFVPS-KLTKMMSDAGVCSRAKSEELCYKTGETLFGFDSSNLNMSRVPVIMSHWGSGTSFKNMVHFGQMVTSGKCQKYNYGYFYNWMKYGQIDPPHYRVKDMDVPTVLFSGSHDTLADPLDV----GELKPRIQNLVHSEEIPGWNHADFLFGMDAERLLYRKIVKMMFK 400
BLAST of Lipase vs. Ensembl Nematostella
Match: EDO38398 (Lipase [Source:UniProtKB/TrEMBL;Acc:A7SCY7]) HSP 1 Score: 279.256 bits (713), Expect = 1.321e-89 Identity = 152/385 (39.48%), Postives = 230/385 (59.74%), Query Frame = 2
Query: 275 CLLIVSING---GLLSPGIE-----TDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRT--SSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKF-VCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAY 1396
CLL+V + LL+ G DP+V +V+++I G+P+E H V T+DGYIL++QRIP+GR SPG +PVVFLQHGLL S +V + SL +ILAD G+DVWLGN RGN YSR H K++ + FWDF+++E ++D+PA I +AL+VS +L YIGHSQGT +GF FS ++ KV F+ALAP+ +L + T ++ A ++ + +F P L+ ++K CG + + C +++ L+ G++ N N +R+P++ TH P+GTS KNI H+ Q + +FDYG N +Y + PP Y + +P A+ G +D ++ DV ++ +V + IPE+NHIDF+ G +AY
Sbjct: 6 CLLVVLLGNQLCCLLAKGTRPKWGPVDPDVNRNVSQLIHNRGFPVEEHDVITKDGYILSVQRIPHGRKGRESPG-PRPVVFLQHGLLADSSCFVQSWEYDSLGYILADNGYDVWLGNIRGNRYSRSHVKYNHKQREFWDFSFEEFGEYDIPAMIEHALSVSGQSQLYYIGHSQGTLVGFISFSTHPEIAKKVKRFIALAPIFHLNHTATIVRDAAFTLGPIQELLFPLGPTQFFPGY-LIKLLTKLGFCGGKYKAKLCYDISELIFGFDDGNANMSRVPVFFTHFPSGTSFKNIIHFGQIVYYGRTARFDYGKRRNMKRYGKPKPPVYDVTKMDVPTALILGTHDNLSTVPDVAPIRAQI-PHVTFYEVIPEWNHIDFVAGIDAY 387
BLAST of Lipase vs. Ensembl Medaka
Match: lipf (lysosomal acid lipase/cholesteryl ester hydrolase-like [Source:NCBI gene;Acc:101156001]) HSP 1 Score: 333.183 bits (853), Expect = 3.257e-110 Identity = 165/372 (44.35%), Postives = 235/372 (63.17%), Query Frame = 2
Query: 329 DPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYG--RTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
DPEV M+++E+I+ +GYP E H+V TEDGYIL++ RIP G RT+ P KP V LQHGLL + WV N P SL F+LAD G+DVW+GNSRGNT+S++H +P + FW F++DEMA DLPA IN+ L V+ D++ YIGHSQGT I F FS +L SKV F LAPV + + + ++ L DA +I +FLP + M++ +CG ++ S CGN+ F+L G++ +NLN TR P+Y TH PAGTS +N+ H+AQ+ K FD+G N YNQ TPP+Y + +P A+F GG D +A +DV + ++ N+ + I + H+DFIWG +A +++P ++ L K+
Sbjct: 37 DPEVNMNISEIIRRWGYPAEEHEVVTEDGYILSVNRIPSGLKRTAGP---KPAVLLQHGLLAAGSNWVTNPPSSSLGFVLADAGYDVWIGNSRGNTWSKRHRTLTPDQEDFWKFSYDEMALKDLPAVINHVLNVTAQDQIFYIGHSQGTTIAFMAFSALPELASKVKLFFGLAPVATVAFTNSPMTKLSVLPDA--LIWDLFGKRDFLPQSDYIKWMAEHICGKRLLSELCGNIFFVLCGFDEKNLNMTRTPVYTTHCPAGTSVQNMVHWAQAVHGGKLMGFDFGPAGNMKHYNQSTPPEYHVKDMKVPTALFSGGQDTLADPKDVAVLLTQVS-NLVYHQHIQHWEHLDFIWGLDAPEQMFPSILKLLQKH 402
BLAST of Lipase vs. Ensembl Medaka
Match: lipf (lysosomal acid lipase/cholesteryl ester hydrolase-like [Source:NCBI gene;Acc:101156001]) HSP 1 Score: 321.627 bits (823), Expect = 7.237e-106 Identity = 162/371 (43.67%), Postives = 231/371 (62.26%), Query Frame = 2
Query: 332 PEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYG--RTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
P V + +E+I+ +GYP E H+V TEDGYIL++ RIP G RT+ P KP V LQHGLL + WV N P SL F+LAD G+DVW+GNSRGNT+S++H +P + FW F++DEMA DLPA IN+ L V+ D++ YIGHSQGT I F FS +L SKV F LAPV + + + ++ L DA +I +FLP + M++ +CG ++ S CGN+ F+L G++ +NLN TR P+Y TH PAGTS +N+ H+AQ+ K FD+G N YNQ TPP+Y + +P A+F GG D +A +DV + ++ N+ + I + H+DFIWG +A +++P ++ L K+
Sbjct: 27 PCVCVVQSEIIRRWGYPAEEHEVVTEDGYILSVNRIPSGLKRTAGP---KPAVLLQHGLLAAGSNWVTNPPSSSLGFVLADAGYDVWIGNSRGNTWSKRHRTLTPDQEDFWKFSYDEMALKDLPAVINHVLNVTAQDQIFYIGHSQGTTIAFMAFSALPELASKVKLFFGLAPVATVAFTNSPMTKLSVLPDA--LIWDLFGKRDFLPQSDYIKWMAEHICGKRLLSELCGNIFFVLCGFDEKNLNMTRTPVYTTHCPAGTSVQNMVHWAQAVHGGKLMGFDFGPAGNMKHYNQSTPPEYHVKDMKVPTALFSGGQDTLADPKDVAVLLTQVS-NLVYHQHIQHWEHLDFIWGLDAPEQMFPSILKLLQKH 391
BLAST of Lipase vs. Ensembl Medaka
Match: lipf (lysosomal acid lipase/cholesteryl ester hydrolase-like [Source:NCBI gene;Acc:101156001]) HSP 1 Score: 319.316 bits (817), Expect = 2.323e-105 Identity = 160/363 (44.08%), Postives = 227/363 (62.53%), Query Frame = 2
Query: 356 EVIKYYGYPLETHQVTTEDGYILTMQRIPYG--RTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
E+I+ +GYP E H+V TEDGYIL++ RIP G RT+ P KP V LQHGLL + WV N P SL F+LAD G+DVW+GNSRGNT+S++H +P + FW F++DEMA DLPA IN+ L V+ D++ YIGHSQGT I F FS +L SKV F LAPV + + + ++ L DA +I +FLP + M++ +CG ++ S CGN+ F+L G++ +NLN TR P+Y TH PAGTS +N+ H+AQ+ K FD+G N YNQ TPP+Y + +P A+F GG D +A +DV + ++ N+ + I + H+DFIWG +A +++P ++ L K+
Sbjct: 10 EIIRRWGYPAEEHEVVTEDGYILSVNRIPSGLKRTAGP---KPAVLLQHGLLAAGSNWVTNPPSSSLGFVLADAGYDVWIGNSRGNTWSKRHRTLTPDQEDFWKFSYDEMALKDLPAVINHVLNVTAQDQIFYIGHSQGTTIAFMAFSALPELASKVKLFFGLAPVATVAFTNSPMTKLSVLPDA--LIWDLFGKRDFLPQSDYIKWMAEHICGKRLLSELCGNIFFVLCGFDEKNLNMTRTPVYTTHCPAGTSVQNMVHWAQAVHGGKLMGFDFGPAGNMKHYNQSTPPEYHVKDMKVPTALFSGGQDTLADPKDVAVLLTQVS-NLVYHQHIQHWEHLDFIWGLDAPEQMFPSILKLLQKH 366
BLAST of Lipase vs. Planmine SMEST
Match: SMESG000074187.1 (SMESG000074187.1) HSP 1 Score: 803.127 bits (2073), Expect = 0.000e+0 Identity = 386/400 (96.50%), Postives = 392/400 (98.00%), Query Frame = 2
Query: 245 INTVAYIRVPCLLIVSINGGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYNN 1444
+N + VPCLLIVSINGGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSL CGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTS+KNIAHYAQSHLSNKFQKFDYGF +NKLKYNQITPP+YPLDTHGLPVAMFYGGNDWMAVKEDV RAIGELGQNVKLIKFIPEYNHIDFIWGANAYT+IYPDVIDFLLKYNN
Sbjct: 1 MNNILLSIVPCLLIVSINGGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLGCGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSTKNIAHYAQSHLSNKFQKFDYGFFMNKLKYNQITPPQYPLDTHGLPVAMFYGGNDWMAVKEDVTRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTKIYPDVIDFLLKYNN 400
BLAST of Lipase vs. Planmine SMEST
Match: SMESG000074186.1 (SMESG000074186.1) HSP 1 Score: 509.99 bits (1312), Expect = 8.504e-180 Identity = 237/380 (62.37%), Postives = 292/380 (76.84%), Query Frame = 2
Query: 299 GGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKY 1438
G L P D E+ M+V E+I YY YP E H VTTEDGYIL++QRIP+G ++ +PVVFLQHGL+DSSFTWV NGP+KSL F+LAD+GFDVWL N+RGN YS H K++ + FWDFTWD+M ++DLPASINY LTV+KA KLGYIGHSQGTEI FAKFS+ SDLNSKV FVALAPVVYLG+LKTAIKY+AGL N++ T GEFLPN +L+ MS FVCGDQ S+ CGN+ FLL G N+N+TR+PIY++H+PA TS KNI HYAQSHL+N+FQ +DYGF N ++Y Q PPKY L+T+GLP+A + G DW++ EDV+RA+ ELG NVK KFIPEYNH+D IWG A +++PDV++FL KY
Sbjct: 17 GQLQPPPASQDSEIKMNVTEIILYYNYPCENHLVTTEDGYILSLQRIPFGLKNNSLQSRPVVFLQHGLVDSSFTWVANGPDKSLGFVLADKGFDVWLSNTRGNVYSNSHIKYTTSDRNFWDFTWDDMVKYDLPASINYVLTVTKAQKLGYIGHSQGTEIAFAKFSENSDLNSKVFGFVALAPVVYLGHLKTAIKYLAGLAGGLNLLANIFTNGEFLPNNELLTTMSTFVCGDQTISILCGNLMFLLYGPGTANMNFTRIPIYLSHVPARTSWKNIVHYAQSHLTNEFQMYDYGFFENLVRYKQAFPPKYRLNTNGLPIAAIWAGADWLSDPEDVSRALNELGDNVKFKKFIPEYNHVDVIWGTTADVKVFPDVVNFLYKY 396
BLAST of Lipase vs. Planmine SMEST
Match: SMESG000007797.1 (SMESG000007797.1) HSP 1 Score: 473.396 bits (1217), Expect = 2.565e-165 Identity = 222/379 (58.58%), Postives = 284/379 (74.93%), Query Frame = 2
Query: 308 LSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYNN 1444
LS ETDPE+ M+V EVI Y YP E H VTTEDGYIL+MQRIP+G S K+PVVFLQHGLLDSSFTWVNN P+KSLAFILAD GFDVWL NSRGN YS KH K+ S FWDF+WDEMAQ+DL ASI Y L+V+K+DK+ YIGHSQGTEI FAK SQ S LNSK+++ VALAPV +LG++++ IKY A + +++++ GEFLP+ + + + +VCGD+ +L CG+ FLL GY+ NLNYTR+PIY+ H PA TS+KN+ HYAQ++ SN+F+ +DYG N Y++I PPKY L+THG+P+A+F+GGNDW+A +DV+ AI G ++KL +FI YNH+DF+WG NA IYPD+I F+ Y N
Sbjct: 22 LSHKYETDPEIYMNVTEVINLYKYPCENHLVTTEDGYILSMQRIPFGIKMSSSSKRPVVFLQHGLLDSSFTWVNNAPDKSLAFILADNGFDVWLANSRGNVYSNKHIKYPTDSNKFWDFSWDEMAQYDLSASIEYVLSVTKSDKISYIGHSQGTEIMFAKLSQNSSLNSKINSVVALAPVAFLGHVQSGIKYFARIAGGLDILLKIFGHGEFLPSSRFMKDLISYVCGDKAPAL-CGDFLFLLTGYDTSNLNYTRLPIYLAHTPAETSAKNMVHYAQAYESNEFKMYDYGIFGNLYYYHEIHPPKYQLNTHGVPLAVFWGGNDWLADYDDVSAAIKIFGNDIKLNRFISYYNHLDFVWGVNAAQLIYPDIIKFINSYRN 399
BLAST of Lipase vs. Planmine SMEST
Match: SMESG000007797.1 (SMESG000007797.1) HSP 1 Score: 472.626 bits (1215), Expect = 3.602e-165 Identity = 222/379 (58.58%), Postives = 284/379 (74.93%), Query Frame = 2
Query: 308 LSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYNN 1444
LS ETDPE+ M+V EVI Y YP E H VTTEDGYIL+MQRIP+G S K+PVVFLQHGLLDSSFTWVNN P+KSLAFILAD GFDVWL NSRGN YS KH K+ S FWDF+WDEMAQ+DL ASI Y L+V+K+DK+ YIGHSQGTEI FAK SQ S LNSK+++ VALAPV +LG++++ IKY A + +++++ GEFLP+ + + + +VCGD+ +L CG+ FLL GY+ NLNYTR+PIY+ H PA TS+KN+ HYAQ++ SN+F+ +DYG N Y++I PPKY L+THG+P+A+F+GGNDW+A +DV+ AI G ++KL +FI YNH+DF+WG NA IYPD+I F+ Y N
Sbjct: 18 LSHKYETDPEIYMNVTEVINLYKYPCENHLVTTEDGYILSMQRIPFGIKMSSSSKRPVVFLQHGLLDSSFTWVNNAPDKSLAFILADNGFDVWLANSRGNVYSNKHIKYPTDSNKFWDFSWDEMAQYDLSASIEYVLSVTKSDKISYIGHSQGTEIMFAKLSQNSSLNSKINSVVALAPVAFLGHVQSGIKYFARIAGGLDILLKIFGHGEFLPSSRFMKDLISYVCGDKAPAL-CGDFLFLLTGYDTSNLNYTRLPIYLAHTPAETSAKNMVHYAQAYESNEFKMYDYGIFGNLYYYHEIHPPKYQLNTHGVPLAVFWGGNDWLADYDDVSAAIKIFGNDIKLNRFISYYNHLDFVWGVNAAQLIYPDIIKFINSYRN 395
BLAST of Lipase vs. Planmine SMEST
Match: SMESG000074185.1 (SMESG000074185.1) HSP 1 Score: 463.766 bits (1192), Expect = 1.458e-161 Identity = 209/374 (55.88%), Postives = 284/374 (75.94%), Query Frame = 2
Query: 323 ETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEMAQFDLPASINYALTVSKADKLGYIGHSQGTEIGFAKFSQFSDLNSKVSAFVALAPVVYLGNLKTAIKYIAGLGDAFNVIMRTVTTGEFLPNIQLVNAMSKFVCGDQMGSLACGNVAFLLQGYNVENLNYTRMPIYVTHIPAGTSSKNIAHYAQSHLSNKFQKFDYGFVINKLKYNQITPPKYPLDTHGLPVAMFYGGNDWMAVKEDVNRAIGELGQNVKLIKFIPEYNHIDFIWGANAYTRIYPDVIDFLLKYNN 1444
+ DPE+ M+ +I+ YGYP+ETH+V TEDGY LT+ RIPYGRT+ + VV+LQHGLLDSSFTW+ N PEKSL FILAD GFDVWLGNSRGN YSR H K+S S +WDF+WDEMA+FDLPAS+++ L V+KA K+ YIGHSQGT I FAKFSQ+S+LN ++S+ VA APV YLGN+++ I+Y+A + ++ + GEFLP ++ +VCG + SL C N+ FLL G + N+NYTR+P+Y++H PAGTSS+N+AH+AQ + SN+F+K+D+G + N Y+QI+PP Y L+T+G+P+AMF+GGND++AV +DV+RAI E +V+ KFIP YNH+DFIWG +A +Y D IDF+LK+++
Sbjct: 28 KRDPEIFMNTTAIIRLYGYPVETHKVLTEDGYFLTLHRIPYGRTNMSAENRRVVYLQHGLLDSSFTWLCNLPEKSLGFILADYGFDVWLGNSRGNVYSRGHLKYSTTSNDYWDFSWDEMAEFDLPASLDHVLRVTKAKKISYIGHSQGTAIAFAKFSQYSNLNERISSIVAYAPVAYLGNIRSGIRYLAYVSGGIDLFYKLFRHGEFLPTTIFTKLLANYVCGMKSASLICSNMIFLLSGPDTSNMNYTRLPVYLSHNPAGTSSRNMAHFAQCYKSNEFKKYDHGLLGNLYHYHQISPPTYNLNTNGIPLAMFWGGNDYLAVPQDVSRAIHEFDHDVEFRKFIPSYNHMDFIWGLSAPEVVYKDTIDFILKHSS 401 The following BLAST results are available for this feature:
BLAST of Lipase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Lipase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Lipase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Lipase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 2
BLAST of Lipase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Lipase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Lipase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Lipase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Lipase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of Lipase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of Lipase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 3
BLAST of Lipase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Lipase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 3
BLAST of Lipase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002911 ID=SMED30002911|Name=Lipase|organism=Schmidtea mediterranea sexual|type=transcript|length=1471bpback to top protein sequence of SMED30002911-orf-1 >SMED30002911-orf-1 ID=SMED30002911-orf-1|Name=SMED30002911-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=368bp MDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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