Potassium voltage-gated channel protein Shaw

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDT--------------ERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            D   R+++NVGG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVFA ILNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY  HR  ++ L       +D               +   E E+ KR  L +  +     FW++W+PRIW++ E+PYSS  A+ V+   +  IL+SI +FC++T+  ++  +      NV  G  +        +E +      Y E +C  WF+ E ++R+I   +   F  + LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        + +E   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQV-----RYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDT--------------ERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            D   R+++NVGG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVFA ILNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY  HR  ++ L       +D               +   E E+ KR  L +  +     FW++W+PRIW++ E+PYSS  A+ V+   +  IL+SI +FC++T+  ++  +      NV  G  +        +E +      Y E +C  WF+ E ++R+I   +   F  + LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        + +E   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQV-----RYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLN---------------EYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRID--------IDTERTSESEL-YKRFGLEE--EFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTK-------NELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            +A  ++I+NVGG RHETY++TL+ +P TRL+ L +      P  +               E+FFDRHPGVFA +LNYYRTGKLH P DVCGPLFEEEL FWG+D   VEPCCWMTY  HR  ++ L I +  D         D     E EL  +R G  E            + W+PR+W++ E+PYSS  A++V+   +  IL+SI +FC++T+  ++I    N T  + +G      +   ++E++   +  Y E +C  WF++E ++R++       F  ++LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+          N+  DF +IP G WWA+ TMTT+GYGDM PKT+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:   33 EASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNID--RNVTEILRVGNITSVHF---RREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 484          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLN---------------EYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRID--------IDTERTSESEL-YKRFGLEE--EFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTK-------NELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            +A  ++I+NVGG RHETY++TL+ +P TRL+ L +      P  +               E+FFDRHPGVFA +LNYYRTGKLH P DVCGPLFEEEL FWG+D   VEPCCWMTY  HR  ++ L I +  D         D     E EL  +R G  E            + W+PR+W++ E+PYSS  A++V+   +  IL+SI +FC++T+  ++I    N T  + +G      +   ++E++   +  Y E +C  WF++E ++R++       F  ++LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+          N+  DF +IP G WWA+ TMTT+GYGDM PKT+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:   33 EASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNID--RNVTEILRVGNITSVHF---RREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 484          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLN---------------EYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRID--------IDTERTSESEL-YKRFGLEE--EFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTK-------NELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            +A  ++I+NVGG RHETY++TL+ +P TRL+ L +      P  +               E+FFDRHPGVFA +LNYYRTGKLH P DVCGPLFEEEL FWG+D   VEPCCWMTY  HR  ++ L I +  D         D     E EL  +R G  E            + W+PR+W++ E+PYSS  A++V+   +  IL+SI +FC++T+  ++I    N T  + +G      +   ++E++   +  Y E +C  WF++E ++R++       F  ++LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+          N+  DF +IP G WWA+ TMTT+GYGDM PKT+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:   33 EASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNID--RNVTEILRVGNITSVHF---RREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 484          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLIL---NHTYNVSIGGDLFQ--SWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAP 1671
            D+E R+ILNVGG+RHETYK TLKKIPATRLS+LT  LANYDP+LNEYFFDRHPGVFAQILNYYRTGKLHYP DVCGPLFEEEL++WGLDSN+ EPCCWMT +  R TQD L+ LD +DI+ ++T   ELYKRFG E+++ ++ LS WQK +PRIW + +EP SS  A+ ++ I +  ++ +II FC+KT+PG  IP +    N + N             ++ +   +PH  F Y E ICN WF+IE++ R     S   +    +NIIDI A L+FYID+    F       +EF SI+RIMRLFKLT H SGLKIL+ TF+ASAKEL LLVFFLV+ + VFA+L+YYAE+   NE N F SIP GLWWAI TMTT+GYGD+ P TY G L+G++CA+ GVLTI+LPVPVIVSNF+MFYSHTQARSK+PKKRR VL ++ V    K AP
Sbjct:    2 DSEYRIILNVGGVRHETYKHTLKKIPATRLSRLTTNLANYDPVLNEYFFDRHPGVFAQILNYYRTGKLHYPLDVCGPLFEEELKYWGLDSNECEPCCWMTLSGTRDTQDVLKTLDELDIEVDQTEGPELYKRFGWEDDYHNDSLSAWQKIKPRIWRLFDEPNSSRSAQFIAAISVFFLITAIIVFCLKTHPGLRIPELAPFGNFSRNHRSTSSRIHPAQINIDKANSRPHPTFMYIETICNIWFTIEILARFSSCPSRFEYLRAPVNIIDIVATLTFYIDLLSSMFGATAD--LEFFSIIRIMRLFKLTHHNSGLKILMHTFRASAKELMLLVFFLVLGVVVFASLVYYAERVESNEDNQFVSIPIGLWWAIVTMTTIGYGDITPHTYLGRLIGSICALAGVLTIALPVPVIVSNFAMFYSHTQARSKMPKKRRGVLSMDQVAQHVKHAP 449          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLIL---NHTYNVSIGGDLFQ--SWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAP 1671
            D+E R+ILNVGG+RHETYK TLKKIPATRLS+LT  LANYDP+LNEYFFDRHPGVFAQILNYYRTGKLHYP DVCGPLFEEEL++WGLDSN+ EPCCWMT +  R TQD L+ LD +DI+ ++T   ELYKRFG E+++ ++ LS WQK +PRIW + +EP SS  A+ ++ I +  ++ +II FC+KT+PG  IP +    N + N             ++ +   +PH  F Y E ICN WF+IE++ R     S   +    +NIIDI A L+FYID+    F       +EF SI+RIMRLFKLT H SGLKIL+ TF+ASAKEL LLVFFLV+ + VFA+L+YYAE+   NE N F SIP GLWWAI TMTT+GYGD+ P TY G L+G++CA+ GVLTI+LPVPVIVSNF+MFYSHTQARSK+PKKRR VL ++ V    K AP
Sbjct:   23 DSEYRIILNVGGVRHETYKHTLKKIPATRLSRLTTNLANYDPVLNEYFFDRHPGVFAQILNYYRTGKLHYPLDVCGPLFEEELKYWGLDSNECEPCCWMTLSGTRDTQDVLKTLDELDIEVDQTEGPELYKRFGWEDDYHNDSLSAWQKIKPRIWRLFDEPNSSRSAQFIAAISVFFLITAIIVFCLKTHPGLRIPELAPFGNFSRNHRSTSSRIHPAQINIDKANSRPHPTFMYIETICNIWFTIEILARFSSCPSRFEYLRAPVNIIDIVATLTFYIDLLSSMFGATAD--LEFFSIIRIMRLFKLTHHNSGLKILMHTFRASAKELMLLVFFLVLGVVVFASLVYYAERVESNEDNQFVSIPIGLWWAIVTMTTIGYGDITPHTYLGRLIGSICALAGVLTIALPVPVIVSNFAMFYSHTQARSKMPKKRRGVLSMDQVAQHVKHAP 470          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLIL---NHTYNVSIGGDLFQ--SWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAP 1671
            D+E R+ILNVGG+RHETYK TLKKIPATRLS+LT  LANYDP+LNEYFFDRHPGVFAQILNYYRTGKLHYP DVCGPLFEEEL++WGLDSN+ EPCCWMT +  R TQD L+ LD +DI+ ++T   ELYKRFG E+++ ++ LS WQK +PRIW + +EP SS  A+ ++ I +  ++ +II FC+KT+PG  IP +    N + N             ++ +   +PH  F Y E ICN WF+IE++ R     S   +    +NIIDI A L+FYID+    F       +EF SI+RIMRLFKLT H SGLKIL+ TF+ASAKEL LLVFFLV+ + VFA+L+YYAE+   NE N F SIP GLWWAI TMTT+GYGD+ P TY G L+G++CA+ GVLTI+LPVPVIVSNF+MFYSHTQARSK+PKKRR VL ++ V    K AP
Sbjct:   20 DSEYRIILNVGGVRHETYKHTLKKIPATRLSRLTTNLANYDPVLNEYFFDRHPGVFAQILNYYRTGKLHYPLDVCGPLFEEELKYWGLDSNECEPCCWMTLSGTRDTQDVLKTLDELDIEVDQTEGPELYKRFGWEDDYHNDSLSAWQKIKPRIWRLFDEPNSSRSAQFIAAISVFFLITAIIVFCLKTHPGLRIPELAPFGNFSRNHRSTSSRIHPAQINIDKANSRPHPTFMYIETICNIWFTIEILARFSSCPSRFEYLRAPVNIIDIVATLTFYIDLLSSMFGATAD--LEFFSIIRIMRLFKLTHHNSGLKILMHTFRASAKELMLLVFFLVLGVVVFASLVYYAERVESNEDNQFVSIPIGLWWAIVTMTTIGYGDITPHTYLGRLIGSICALAGVLTIALPVPVIVSNFAMFYSHTQARSKMPKKRRGVLSMDQVAQHVKHAP 467          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSI---GG--DLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLI--EFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNF----LTSSNAAWVQ-NRRLAITGKGPSLIDEKLQRL 1773
            D E+RVILNVGGIRHETY   LKKIPATRLS+LT  LANYDP+LNEYFFDRHPGVF+ ILNYYRTGKLHYPT+VCGPLFEEELEFWGLD+NQVEPCCWMTYT HR TQDTL +++ +D+D +  ++ E+ K+FG E+++    +S WQ+ +PR+W++ +EP+SS  A+++S + ++ IL S  SF +KT P + IP I +  Y++ +   GG  +  ++    +    PH  FFY + ICN WF+IEL++R +   S   F    L IID+ +  +F+ +       I+   L+  +F+S++ ++RLFKLT+H SGLKILI TFKASA+EL LLVFF+++ I +FAAL+YYAE+   N+ N FTSIP GLWW++ T++TVG+GDMVPKTY GMLVG+LCA+ GVLTI+LPVPVIVSNFS  YSH+QAR+KLPKKRRRVL    V+P   G   +       SS+A + Q          GPS+ D    +L
Sbjct:    2 DTEHRVILNVGGIRHETYSHVLKKIPATRLSRLTPNLANYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLDANQVEPCCWMTYTQHRDTQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARVISSLSVAFILASTCSFILKTDPSFQIPDI-DVFYSLRVVDEGGFKNYHKTIGTDKPVTSPHPNFFYVDLICNIWFTIELLIRSLFCPSFHKFVRSPLTIIDVISTGAFFFESLLHAILIQTGSLVTLDFLSMICVLRLFKLTQHFSGLKILIQTFKASAQELFLLVFFVILAIVIFAALVYYAERSQLNKDNQFTSIPLGLWWSLVTISTVGFGDMVPKTYLGMLVGSLCALMGVLTIALPVPVIVSNFSNLYSHSQARAKLPKKRRRVLQAHEVKPALLGVKQHHGKHRKKSSSATFNQPPANFKNANGGPSMHDNSASKL 491          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSI---GG--DLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLI--EFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNF----LTSSNAAWVQ-NRRLAITGKGPSLIDEKLQRL 1773
            D E+RVILNVGGIRHETY   LKKIPATRLS+LT  LANYDP+LNEYFFDRHPGVF+ ILNYYRTGKLHYPT+VCGPLFEEELEFWGLD+NQVEPCCWMTYT HR TQDTL +++ +D+D +  ++ E+ K+FG E+++    +S WQ+ +PR+W++ +EP+SS  A+++S + ++ IL S  SF +KT P + IP I +  Y++ +   GG  +  ++    +    PH  FFY + ICN WF+IEL++R +   S   F    L IID+ +  +F+ +       I+   L+  +F+S++ ++RLFKLT+H SGLKILI TFKASA+EL LLVFF+++ I +FAAL+YYAE+   N+ N FTSIP GLWW++ T++TVG+GDMVPKTY GMLVG+LCA+ GVLTI+LPVPVIVSNFS  YSH+QAR+KLPKKRRRVL    V+P   G   +       SS+A + Q          GPS+ D    +L
Sbjct:    2 DTEHRVILNVGGIRHETYSHVLKKIPATRLSRLTPNLANYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLDANQVEPCCWMTYTQHRDTQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARVISSLSVAFILASTCSFILKTDPSFQIPDI-DVFYSLRVVDEGGFKNYHKTIGTDKPVTSPHPNFFYVDLICNIWFTIELLIRSLFCPSFHKFVRSPLTIIDVISTGAFFFESLLHAILIQTGSLVTLDFLSMICVLRLFKLTQHFSGLKILIQTFKASAQELFLLVFFVILAIVIFAALVYYAERSQLNKDNQFTSIPLGLWWSLVTISTVGFGDMVPKTYLGMLVGSLCALMGVLTIALPVPVIVSNFSNLYSHSQARAKLPKKRRRVLQAHEVKPALLGVKQHHGKHRKKSSSATFNQPPANFKNANGGPSMHDNSASKL 491          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYF--NIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVR-PKFKGAPNNFL-TSSNAAWVQNRRLAITGKGPSLIDEKLQRLALQQLIPM-KSLAGNTNLGMALLNRSLIMNDKT 1869
            D+ENRV+LNVGGIRHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVFAQ+LNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYT HR TQ+TL +LDR+D+DTE+ SE EL ++FG EE++    +S+WQ+ +PRIWS+ +EPYSS  AK +  + +  I ISI+SFC+KT+P   +P++ N T   + G +    W L + +   H  FFY EC+CNAWF+ E+++R I + +   F    +NIID  A LSFYID+    F  ++E + ++EF SI+RIMRLFKLTRH SGLKILI TF+ASAKEL+LLVFFLV+ I +FA+L+YYAE+   N  NDF SIP GLWWA+ TMTTVGYGDM PKTY GM VGALCA+ GVLTI+LPVPVIVSNF+M+YSHTQAR+KLPKKRRRVLPVE  R P+  GAP       +  +   +  +   G GP  ++ K + L   +  P+  S+   +   M  LN +L M   T
Sbjct:    7 DSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSN---GWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVSGCGTPGSGPHSGPMGSGGTGPRRMNNKTKDLVSPKSGPLGASIVAMSPRTMLDLNPALAMGKPT 519          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYF--NIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVR-PKFKGAPNNFL-TSSNAAWVQNRRLAITGKGPSLIDEKLQRL----ALQQLI--PM-KSLAGNTNLGMALLNRSLIMNDKT 1869
            D+ENRV+LNVGGIRHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVFAQ+LNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYT HR TQ+TL +LDR+D+DTE+ SE EL ++FG EE++    +S+WQ+ +PRIWS+ +EPYSS  AK +  + +  I ISI+SFC+KT+P   +P++ N T   + G +    W L + +   H  FFY EC+CNAWF+ E+++R I + +   F    +NIID  A LSFYID+    F  ++E + ++EF SI+RIMRLFKLTRH SGLKILI TF+ASAKEL+LLVFFLV+ I +FA+L+YYAE+   N  NDF SIP GLWWA+ TMTTVGYGDM PKTY GM VGALCA+ GVLTI+LPVPVIVSNF+M+YSHTQAR+KLPKKRRRVLPVE  R P+  GAP       +  +   +  +   G GP  ++ K + L    ++ QL   P+  S+   +   M  LN +L M   T
Sbjct:   22 DSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSN---GWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVSGCGTPGSGPHSGPMGSGGTGPRRMNNKTKDLVSPKSVAQLFAGPLGASIVAMSPRTMLDLNPALAMGKPT 540          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYF--NIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVR-PKFKGAPNNFL-TSSNAAWVQNRRLAITGKGPSLIDEKLQRL----ALQQLI--PM-KSLAGNTNLGMALLNRSLIMNDKT 1869
            D+ENRV+LNVGGIRHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVFAQ+LNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYT HR TQ+TL +LDR+D+DTE+ SE EL ++FG EE++    +S+WQ+ +PRIWS+ +EPYSS  AK +  + +  I ISI+SFC+KT+P   +P++ N T   + G +    W L + +   H  FFY EC+CNAWF+ E+++R I + +   F    +NIID  A LSFYID+    F  ++E + ++EF SI+RIMRLFKLTRH SGLKILI TF+ASAKEL+LLVFFLV+ I +FA+L+YYAE+   N  NDF SIP GLWWA+ TMTTVGYGDM PKTY GM VGALCA+ GVLTI+LPVPVIVSNF+M+YSHTQAR+KLPKKRRRVLPVE  R P+  GAP       +  +   +  +   G GP  ++ K + L    ++ QL   P+  S+   +   M  LN +L M   T
Sbjct:    7 DSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSN---GWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVSGCGTPGSGPHSGPMGSGGTGPRRMNNKTKDLVSPKSVAQLFAGPLGASIVAMSPRTMLDLNPALAMGKPT 525          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYF--NIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVR-PKFKGAPNNFL-TSSNAAWVQNRRLAITGKGPSLIDEKLQRL 1773
            D+ENRV+LNVGGIRHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVFAQ+LNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYT HR TQ+TL +LDR+D+DTE+ SE EL ++FG EE++    +S+WQ+ +PRIWS+ +EPYSS  AK +  + +  I ISI+SFC+KT+P   +P++ N T   + G +    W L + +   H  FFY EC+CNAWF+ E+++R I + +   F    +NIID  A LSFYID+    F  ++E + ++EF SI+RIMRLFKLTRH SGLKILI TF+ASAKEL+LLVFFLV+ I +FA+L+YYAE+   N  NDF SIP GLWWA+ TMTTVGYGDM PKTY GM VGALCA+ GVLTI+LPVPVIVSNF+M+YSHTQAR+KLPKKRRRVLPVE  R P+  GAP       +  +   +  +   G GP  ++ K + L
Sbjct:    7 DSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSN---GWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVSGCGTPGSGPHSGPMGSGGTGPRRMNNKTKDL 486          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYF--NIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVR-PKFKGAPNNFL-TSSNAAWVQNRRLAITGKGPSLIDEKLQRL 1773
            D+ENRV+LNVGGIRHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVFAQ+LNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYT HR TQ+TL +LDR+D+DTE+ SE EL ++FG EE++    +S+WQ+ +PRIWS+ +EPYSS  AK +  + +  I ISI+SFC+KT+P   +P++ N T   + G +    W L + +   H  FFY EC+CNAWF+ E+++R I + +   F    +NIID  A LSFYID+    F  ++E + ++EF SI+RIMRLFKLTRH SGLKILI TF+ASAKEL+LLVFFLV+ I +FA+L+YYAE+   N  NDF SIP GLWWA+ TMTTVGYGDM PKTY GM VGALCA+ GVLTI+LPVPVIVSNF+M+YSHTQAR+KLPKKRRRVLPVE  R P+  GAP       +  +   +  +   G GP  ++ K + L
Sbjct:    7 DSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSN---GWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVSGCGTPGSGPHSGPMGSGGTGPRRMNNKTKDL 486          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQI-------LDRIDIDTER-------TSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFF--YTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYF-NIEKSHLIEFMSI---LRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKN-------ELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            D ++RV++NVGGIRH+TY++TL+ +P TRL+ L E  A    +YD  ++E+FFDRHPGVFA ILNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY  HR  ++ L         +   D+DTE          E E+ KR  + +  +     FWQ+W+ R+W++ E+PYSS  A+ V+   +  IL+SI +FC++T+  ++   I+N TY       +    + S+  ++  TV +  Y E +C  WF+ E ++R+      + F  + LNIID  A+L FY++V      + E   ++ F+ +   +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+   N       E   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DEKDRVVINVGGIRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDAQIDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGPVEMGNDDMDTEALGDPGDGDEELEMTKRLAVGDSPDTKGAGFWQRWQRRVWALFEDPYSSKYARWVAFASLFFILVSITTFCLETHEAFNP--IINRTY-------VNTQDNTSRFHLETETVVYLTYIEGVCVVWFTFEFLMRVTFCPDKKKFIKNTLNIIDFVAILPFYLEVGLSGLSSSEAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 446          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQI-------LDRIDIDTER-------TSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFF--YTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYF-NIEKSHLIEFMSI---LRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKN-------ELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            D ++RV++NVGGIRH+TY++TL+ +P TRL+ L E  A    +YD  ++E+FFDRHPGVFA ILNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY  HR  ++ L         +   D+DTE          E E+ KR  + +  +     FWQ+W+ R+W++ E+PYSS  A+ V+   +  IL+SI +FC++T+  ++   I+N TY       +    + S+  ++  TV +  Y E +C  WF+ E ++R+      + F  + LNIID  A+L FY++V      + E   ++ F+ +   +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+   N       E   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DEKDRVVINVGGIRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDAQIDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGPVEMGNDDMDTEALGDPGDGDEELEMTKRLAVGDSPDTKGAGFWQRWQRRVWALFEDPYSSKYARWVAFASLFFILVSITTFCLETHEAFNP--IINRTY-------VNTQDNTSRFHLETETVVYLTYIEGVCVVWFTFEFLMRVTFCPDKKKFIKNTLNIIDFVAILPFYLEVGLSGLSSSEAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 446          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQI-------LDRIDIDTER-------TSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFF--YTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYF-NIEKSHLIEFMSI---LRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKN-------ELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            D ++RV++NVGGIRH+TY++TL+ +P TRL+ L E  A    +YD  ++E+FFDRHPGVFA ILNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY  HR  ++ L         +   D+DTE          E E+ KR  + +  +     FWQ+W+ R+W++ E+PYSS  A+ V+   +  IL+SI +FC++T+  ++   I+N TY       +    + S+  ++  TV +  Y E +C  WF+ E ++R+      + F  + LNIID  A+L FY++V      + E   ++ F+ +   +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+   N       E   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DEKDRVVINVGGIRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDAQIDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGPVEMGNDDMDTEALGDPGDGDEELEMTKRLAVGDSPDTKGAGFWQRWQRRVWALFEDPYSSKYARWVAFASLFFILVSITTFCLETHEAFNP--IINRTY-------VNTQDNTSRFHLETETVVYLTYIEGVCVVWFTFEFLMRVTFCPDKKKFIKNTLNIIDFVAILPFYLEVGLSGLSSSEAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 446          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTE---------------ALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFE-DNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLS----QKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            D   RVILNVGG RHETY++TLK +P TRL+ L                     Y    NEYFFDRHPGVFA +LNYYRTGKLH P DVCGPLFEEEL FWG+D   VEPCCWMTY  HR  ++ L + + +++DTE   + E  KR G+E+    D  +S W++W+P IW++ ++PYSS  A+ ++   +  I++SI +FC++T+  ++   I+N T       D  ++ +L+    Q EI+      Y E +C  WF+ E ++R+  +     F   VLNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        T +    F +IP G WWA+ TMTT+GYGDM P+T+ GM+VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DERERVILNVGGTRHETYRSTLKTLPGTRLALLASESDLELVLDQLQQVPGFIEYSARSNEYFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELSFWGIDETDVEPCCWMTYRQHRDAEEALDVFE-MNVDTEE--DDEYGKRLGIEDVVSADGTVSRWRRWQPVIWNLFDDPYSSRAARFIAFASLFFIMVSITTFCLETHEAFNT--IINKT-------DPLRNETLTDISQQYEIETDPALTYVEGVCVLWFTFEFLVRITFSPDKLEFIKSVLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPNDPTASHHTMFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMVVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 443          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTE---------------ALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFE-DNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLS----QKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            D   RVILNVGG RHETY++TLK +P TRL+ L                     Y    NEYFFDRHPGVFA +LNYYRTGKLH P DVCGPLFEEEL FWG+D   VEPCCWMTY  HR  ++ L + + +++DTE   + E  KR G+E+    D  +S W++W+P IW++ ++PYSS  A+ ++   +  I++SI +FC++T+  ++   I+N T       D  ++ +L+    Q EI+      Y E +C  WF+ E ++R+  +     F   VLNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        T +    F +IP G WWA+ TMTT+GYGDM P+T+ GM+VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DERERVILNVGGTRHETYRSTLKTLPGTRLALLASESDLELVLDQLQQVPGFIEYSARSNEYFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELSFWGIDETDVEPCCWMTYRQHRDAEEALDVFE-MNVDTEE--DDEYGKRLGIEDVVSADGTVSRWRRWQPVIWNLFDDPYSSRAARFIAFASLFFIMVSITTFCLETHEAFNT--IINKT-------DPLRNETLTDISQQYEIETDPALTYVEGVCVLWFTFEFLVRITFSPDKLEFIKSVLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPNDPTASHHTMFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMVVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 443          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLT--------------EALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTS-----ESELYKRFGLEEEF-EDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLP 1635
            D   R+ILNVGG RHETY++TLK +P TRL+ L                   N     NE+FFDRHPGVFA +LNYYRTGKLH P DVCGPLFEEEL FWG+D   VEPCCWMTY  HR  ++ L I +  D+ T         E +L KR  +E+    D ++  W++ +PR+W++ E+PYSS  A+ ++   +  IL+SI +FC++T+  ++   I+N T  V+ G +L     +S  EI+      Y E +C  WF+ E ++R+I       F  ++LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        + ++   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLP+KR++ +P
Sbjct:    5 DENERIILNVGGTRHETYRSTLKTVPGTRLALLACESQSEQGLDQQTVSGSFNITSRGNEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLITGEPPPIDEYEEDLGKRLAIEDVVCPDGKVGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNT--IINKTETVNNGTEL-----ISLIEIETDPALTYVEGVCVVWFTFEFLVRVIFCPDKLEFIRNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPSDPSASKHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKYIP 461          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLT--------------EALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTS-----ESELYKRFGLEEEF-EDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLP 1635
            D   R+ILNVGG RHETY++TLK +P TRL+ L                   N     NE+FFDRHPGVFA +LNYYRTGKLH P DVCGPLFEEEL FWG+D   VEPCCWMTY  HR  ++ L I +  D+ T         E +L KR  +E+    D ++  W++ +PR+W++ E+PYSS  A+ ++   +  IL+SI +FC++T+  ++   I+N T  V+ G +L     +S  EI+      Y E +C  WF+ E ++R+I       F  ++LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        + ++   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLP+KR++ +P
Sbjct:    5 DENERIILNVGGTRHETYRSTLKTVPGTRLALLACESQSEQGLDQQTVSGSFNITSRGNEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLITGEPPPIDEYEEDLGKRLAIEDVVCPDGKVGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNT--IINKTETVNNGTEL-----ISLIEIETDPALTYVEGVCVVWFTFEFLVRVIFCPDKLEFIRNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPSDPSASKHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKYIP 461          

Query:  346 NRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEK-------FTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPN 1674
            +++++NVGGIRHETY++TLK +P TRLS LTE  A    +YDP  +E+FFDRHP VFA +LNYYRTGKLH P DVCGPL+EEEL FWG+D   VE CCWM Y  HR  ++ L         TE   + +L KR  L+E  +  +L  W++ +P++W++ E+PYSS  A+ ++   +  ILISI +FC++T+  ++    +N+   V   G++ ++ ++ + E +P     Y E IC  WF+ E ++R+I       F    LNIID  A+L FY+++     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        T ++  DF +IP G WWA+ TMTT+GYGDM P T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    RP   G+PN
Sbjct:   36 DKIVINVGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKTDEFFFDRHPQVFAYVLNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSF-ETPEPTEEEEDGDL-KRLCLQE--DGRKLGRWKRLQPKVWALFEDPYSSKAARYIAFASLFFILISITTFCLETHEAFN---DVNNKTEVFTQGNITRTETILEMETEPFLT--YVEGICVIWFTFEFLIRVIFCPDKMEFIKSSLNIIDFVAILPFYLEIGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAAPDDITGSKHTDFKNIPIGFWWAVVTMTTLGYGDMYPVTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP----RPPQPGSPN 480          

Query:  346 NRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEK-------FTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPN 1674
            +++++NVGGIRHETY++TLK +P TRLS LTE  A    +YDP  +E+FFDRHP VFA +LNYYRTGKLH P DVCGPL+EEEL FWG+D   VE CCWM Y  HR  ++ L         TE   + +L KR  L+E  +  +L  W++ +P++W++ E+PYSS  A+ ++   +  ILISI +FC++T+  ++    +N+   V   G++ ++ ++ + E +P     Y E IC  WF+ E ++R+I       F    LNIID  A+L FY+++     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        T ++  DF +IP G WWA+ TMTT+GYGDM P T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    RP   G+PN
Sbjct:   36 DKIVINVGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKTDEFFFDRHPQVFAYVLNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSF-ETPEPTEEEEDGDL-KRLCLQE--DGRKLGRWKRLQPKVWALFEDPYSSKAARYIAFASLFFILISITTFCLETHEAFN---DVNNKTEVFTQGNITRTETILEMETEPFLT--YVEGICVIWFTFEFLIRVIFCPDKMEFIKSSLNIIDFVAILPFYLEIGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAAPDDITGSKHTDFKNIPIGFWWAVVTMTTLGYGDMYPVTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP----RPPQPGSPN 480          

Query:  346 NRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEK-------FTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPN 1674
            +++++NVGGIRHETY++TLK +P TRLS LTE  A    +YDP  +E+FFDRHP VFA +LNYYRTGKLH P DVCGPL+EEEL FWG+D   VE CCWM Y  HR  ++ L         TE   + +L KR  L+E  +  +L  W++ +P++W++ E+PYSS  A+ ++   +  ILISI +FC++T+  ++    +N+   V   G++ ++ ++ + E +P     Y E IC  WF+ E ++R+I       F    LNIID  A+L FY+++     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        T ++  DF +IP G WWA+ TMTT+GYGDM P T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    RP   G+PN
Sbjct:   36 DKIVINVGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKTDEFFFDRHPQVFAYVLNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSF-ETPEPTEEEEDGDL-KRLCLQE--DGRKLGRWKRLQPKVWALFEDPYSSKAARYIAFASLFFILISITTFCLETHEAFN---DVNNKTEVFTQGNITRTETILEMETEPFLT--YVEGICVIWFTFEFLIRVIFCPDKMEFIKSSLNIIDFVAILPFYLEIGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAAPDDITGSKHTDFKNIPIGFWWAVVTMTTLGYGDMYPVTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP----RPPQPGSPN 480          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDT--------------ERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            D   R+++NVGG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVFA ILNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY  HR  ++ L       +D               +   E E+ KR  L +  +     FW++W+PRIW++ E+PYSS  A+ V+   +  IL+SI +FC++T+  ++  +      NV  G  +        +E +      Y E +C  WF+ E ++R++   +   F  + LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        + +E   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQV-----RYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDT--------------ERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            D   R+++NVGG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVFA ILNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY  HR  ++ L       +D               +   E E+ KR  L +  +     FW++W+PRIW++ E+PYSS  A+ V+   +  IL+SI +FC++T+  ++  +      NV  G  +        +E +      Y E +C  WF+ E ++R++   +   F  + LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        + +E   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQV-----RYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLN-------------------EYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERT--------SESEL-YKRFGLEE--EFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVS-IGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTK-------NELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            +A  ++I+NVGG RHETY++TL+ +P TRL+ L +      P  +                   E+FFDRHPGVFA +LNYYRTGKLH P DVCGPLFEEEL FWG+D   VEPCCWMTY  HR  ++ L I +  D               E EL  +R G  E            + W+PR+W++ E+PYSS  A++V+   +  IL+SI +FC++T+  ++I   +   + V  I    F      ++E++   +  Y E +C  WF++E ++R++       F  ++LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+          N+  DF +IP G WWA+ TMTT+GYGDM PKT+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:   33 EASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPESDGGGAGSSGSSGGGGGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGGGAGPGDEAGDDERELALQRLGPHEGGSGPGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEIHRVGNITSVRF------RREVETEPILTYIEGVCVMWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 488          

Query:  349 RVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEE-------------------FEDNEL--------------SFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELND-------FTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPN 1674
            ++++NVGG+RHETY++TL+ +P TRL+ LTE  A    +YDP  +E+FFDRHPGVFA +LNYYRTGKLH P DVCGPLFEEEL FWG+D   VE CCWMTY  HR  ++ L   +  D      + +      GL++E                   F+D                 ++W++W+PR+W++ E+PYSS  A+ V+   +  ILISI +FC++T+ G+    I N T   +         +++  E++      Y E +C  WF+ E ++R+        F    LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+   +  +        F +IP G WWA+ TMTT+GYGDM PKT+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    RP   G+PN
Sbjct:   91 KIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGTDEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDSSANANANAGGAHDAGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPAGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFI--HISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRVTFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP----RPPQPGSPN 574          

Query:  349 RVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEE-------------------FEDNEL--------------SFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELND--------FTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPN 1674
            ++++NVGG+RHETY++TL+ +P TRL+ LTE  A    +YDP  +E+FFDRHPGVFA +LNYYRTGKLH P DVCGPLFEEEL FWG+D   VE CCWMTY  HR  ++ L   +  D      + +      GL++E                   F+D                 ++W++W+PR+W++ E+PYSS  A+ V+   +  ILISI +FC++T+ G+    I N T   +         +++  E++      Y E +C  WF+ E ++R+        F    LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+   +  +D        F +IP G WWA+ TMTT+GYGDM PKT+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    RP   G+PN
Sbjct:   91 KIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGTDEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDSSANANANAGGAHDAGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPAGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFI--HISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRVTFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADP-DDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP----RPPQPGSPN 574          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYF--NIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVR-PKFKGAPNNFL-TSSNAAWVQNRRLAITGKGPSLIDEKLQRL 1773
            D+ENRV+LNVGGIRHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVFAQ+LNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYT HR TQ+TL +LDR+D+DTE+ SE EL ++FG EE++    +S+WQ+ +PRIWS+ +EPYSS  AK +  + +  I ISI+SFC+KT+P   +P++ N T   + G +    W L + +   H  FFY EC+CNAWF+ E+++R I + +   F    +NIID  A LSFYID+    F  ++E + ++EF SI+RIMRLFKLTRH SGLKILI TF+ASAKEL+LLVFFLV+ I +FA+L+YYAE+   N  NDF SIP GLWWA+ TMTTVGYGDM PKTY GM VGALCA+ GVLTI+LPVPVIVSNF+M+YSHTQAR+KLPKKRRRVLPVE  R P+  GAP       +  +   +  +   G GP  ++ K + L
Sbjct:    7 DSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSN---GWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVSGCGTPGSGPHSGPMGSGGTGPRRMNNKTKDL 486          

Query:  325 SKMTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTE---RTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFV-YFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVR 1650
             K    + R++LNVGG+RHETY+ATLKKIPATRLS+LT +LAN+DP+LNEYFFDRHP VFA ILNYYRTGKLHYPTDVCGPLFEEEL++WGLD++  EPCCWM     + TQ+TL +LDR+D D E   +  E +  K+FG EE++   + + W K +P++WS+ +EPYSS  AKL++GI +  I ISI SFC+KT+  + +P+++    N+++ G + Q  S+ +   +P  +F   E +CN WF++ELI+R +   S   FF   LN+ID+ A LSFY D   V     E   ++EF+S++RI RLFKLT+H  GL+ILI TF+ASAKEL LLVFFL++ I +FAAL+YYAEK   N  N F SIP GLWWAICTMTTVGYGDM P T  G LVG+LCAV GVLTI+LPVPVIVSNF+MFYSH QAR KLPK+RRRVLPVE +R
Sbjct:   30 DKGISMDERIVLNVGGVRHETYQATLKKIPATRLSRLTPSLANFDPLLNEYFFDRHPAVFAMILNYYRTGKLHYPTDVCGPLFEEELQYWGLDASDTEPCCWMQLLHAKDTQETLAVLDRMDADHEDDPQLREQDTMKKFGWEEDYFQGKRTRWMKLKPQMWSLFDEPYSSQAAKLIAGISVLFIFISIFSFCLKTHQSFRLPVLIGQ--NITMPGGVVQP-SIERVSTEPLPIFGQIEMLCNIWFTLELIIRFVFCPSKIRFFKSPLNMIDLVATLSFYADAMMVRVVEDEPKDVVEFLSMIRIFRLFKLTQHHQGLQILIHTFRASAKELILLVFFLILGIVIFAALVYYAEKMEANPNNQFQSIPLGLWWAICTMTTVGYGDMTPHTSFGRLVGSLCAVMGVLTIALPVPVIVSNFAMFYSHNQARDKLPKRRRRVLPVEQIR 472          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDT--------------ERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            D   R+++NVGG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVFA ILNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY  HR  ++ L       +D               +   E E+ KR  L +  +     FW++W+PRIW++ E+PYSS  A+ V+   +  IL+SI +FC++T+  ++  +      NV  G  +        +E +      Y E +C  WF+ E ++R+I   +   F  + LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        + +E   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQV-----RYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDT--------------ERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            D   R+++NVGG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVFA ILNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY  HR  ++ L       +D               +   E E+ KR  L +  +     FW++W+PRIW++ E+PYSS  A+ V+   +  IL+SI +FC++T+  ++  +      NV  G  +        +E +      Y E +C  WF+ E ++R++   +   F  + LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        + +E   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQV-----RYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDT--------------ERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            D   R+++NVGG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVFA ILNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY  HR  ++ L       +D               +   E E+ KR  L +  +     FW++W+PRIW++ E+PYSS  A+ V+   +  IL+SI +FC++T+  ++  +      NV  G  +        +E +      Y E +C  WF+ E ++R++   +   F  + LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        + +E   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQV-----RYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  331 MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSF--VYFNIEKSH-LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKG-APNNFLTSSNAAWVQN-RRLAITGKGPSLIDEKLQRLALQQLIPM 1797
            M DA+NRVILNVGGIRHETYKATLKKIPATRLS+LTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYT HR TQ+TL ILDR+D+DT++ +  +LYK+FGLE+++E+NEL+ WQK +P++W++ +EPYSSV AK+V+ + +  I+ISI+SFC+KT+PG  +P+I N T  V +  +   S++L +   +PH+ FFY EC+CN+WF+ E++ R  VT     F    +NIID  A LSFY+D+    V    E S+ ++EF SI+RIMRLFKLTRHI+GLKILI TFKASAKEL LLVFFL+VFI VFAALIYYAE+   N  N F SIP GLWWAI TMTTVGYGDM PKTY GM VGALCA+TGVLTI+LPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPK  G  P + L         N RR      GP L+D KL RL    L  M
Sbjct:    1 MADADNRVILNVGGIRHETYKATLKKIPATRLSRLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTTHRETQETLTILDRLDLDTDKLAPEDLYKKFGLEDKYENNELNLWQKVKPKLWALFDEPYSSVAAKIVAVVSVFFIVISILSFCLKTFPGLRVPIITNVT--VVVDSNDTMSYALYKTRSEPHSAFFYIECVCNSWFTFEIVTRFSVTPDKFEFLKSPVNIIDFIATLSFYMDLVLNQVLSEAEASYEVLEFFSIIRIMRLFKLTRHIAGLKILIHTFKASAKELLLLVFFLIVFIVVFAALIYYAERIHYNPENSFDSIPIGLWWAIVTMTTVGYGDMAPKTYAGMFVGALCALTGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKVAGTGPGSGLLKGAGGAGGNARRFNAMKSGPGLLDSKLNRLGATTLQSM 492          

Query:  331 MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSF--VYFNIEKSH-LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNFLTSSNAAWVQNRRLAITG--KGPSLIDEKLQRLALQQLIPMKS 1803
            M+DA+NRVILNVGGIRHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYT+HR TQ+TL ILDR+D+DT++ +E +LYK+FG EEEF  N+L+FWQ+ +P++W++ +EPYSS+ AK+V+ + +  I+ISI+SFC+KT+PG  +P+I N T  +   G    S+ L +   +PHT F Y EC+CN+WF+ E+I R  VT   R F    +NIID  A LSFY+D+    V    E S+ ++EF SI+RIMRLFKLTRHI+GLKILI TFKASAKEL LLVFFL+VFI VFAALIYYAE+   N  N F SIP GLWWAI TMTTVGYGDM PKTY GMLVGALCA+TGVLTI+LPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPK + A               +R  + G   GP L+D KL RL    L  M S
Sbjct:    1 MSDADNRVILNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTSHRETQETLGILDRLDLDTDKLAEEDLYKKFGWEEEFLSNKLNFWQRIKPKLWALFDEPYSSMAAKIVAVVSVFFIVISILSFCLKTFPGLRVPIISNETVLIDENGS--TSFVLHKHRSEPHTAFLYIECVCNSWFTFEIITRFAVTPDKREFLKSPVNIIDFIATLSFYMDMVLNQVLSEEETSYEVLEFFSIIRIMRLFKLTRHIAGLKILIHTFKASAKELLLLVFFLIVFIVVFAALIYYAERIQYNPENSFDSIPIGLWWAIVTMTTVGYGDMAPKTYAGMLVGALCALTGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKSQSA------GPVGPKGPGQRGGLEGMKSGPGLLDSKLNRLGANTLQSMMS 488          

Query:  331 MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSF--VYFNIEKSH-LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNFLTSSNAAWVQNRRLAITG--KGPSLIDEKLQRLALQQLIPMKS 1803
            M+DA+NRVILNVGGIRHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYT+HR TQ+TL ILDR+D+DT++ +E +LYK+FG EEEF  N+L+FWQ+ +P++W++ +EPYSS+ AK+V+ + +  I+ISI+SFC+KT+PG  +P+I N T  +   G    S+ L +   +PHT F Y EC+CN+WF+ E+I R  VT   R F    +NIID  A LSFY+D+    V    E S+ ++EF SI+RIMRLFKLTRHI+GLKILI TFKASAKEL LLVFFL+VFI VFAALIYYAE+   N  N F SIP GLWWAI TMTTVGYGDM PKTY GMLVGALCA+TGVLTI+LPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPK + A               +R  + G   GP L+D KL RL    L  M S
Sbjct:    1 MSDADNRVILNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTSHRETQETLGILDRLDLDTDKLAEEDLYKKFGWEEEFLSNKLNFWQRIKPKLWALFDEPYSSMAAKIVAVVSVFFIVISILSFCLKTFPGLRVPIISNETVLIDENGS--TSFVLHKHRSEPHTAFLYIECVCNSWFTFEIITRFAVTPDKREFLKSPVNIIDFIATLSFYMDMVLNQVLSEEETSYEVLEFFSIIRIMRLFKLTRHIAGLKILIHTFKASAKELLLLVFFLIVFIVVFAALIYYAERIQYNPENSFDSIPIGLWWAIVTMTTVGYGDMAPKTYAGMLVGALCALTGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKSQSA------GPMGPKGPGQRGGLEGMKSGPGLLDSKLNRLGANTLQSMMS 488          

Query:  331 MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSF--VYFNIEKSH-LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNFLTSSNAAWVQNRRLAITG--KGPSLIDEKLQRLALQQLIPMKS 1803
            M+DA+NRVILNVGGIRHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYT+HR TQ+TL ILDR+D+DT++ +E +LYK+FG EEEF  NEL+FWQ+ +P++W++ +EPYSS+ AK+V+ + +  I+ISI+SFC+KT+PG  +P+I N T  +   G    S+ L +   +PHT F Y EC+CN+WF+ E+I R  VT     F    +NIID  A LSFY+D+    V    E S+ ++EF SI+RIMRLFKLTRHI+GLKILI TFKASAKEL LLVFFL+VFI VFAALIYYAE+   N  N F SIP GLWWAI TMTTVGYGDM PKTY GMLVGALCA+TGVLTI+LPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPK + A               +R  + G   GP L+D KL RL    L  M S
Sbjct:    1 MSDADNRVILNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTSHRETQETLGILDRLDLDTDKLAEEDLYKKFGWEEEFLSNELNFWQRIKPKLWALFDEPYSSMAAKIVAVVSVFFIVISILSFCLKTFPGLRVPIISNETVLIDENGS--TSFVLHKHRSEPHTAFLYIECVCNSWFTFEIITRFAVTPDKLEFLKSPVNIIDFIATLSFYMDMVLNQVLSEEETSYEVLEFFSIIRIMRLFKLTRHIAGLKILIHTFKASAKELLLLVFFLIVFIVVFAALIYYAERIQYNPENSFDSIPIGLWWAIVTMTTVGYGDMAPKTYAGMLVGALCALTGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKSQSA------GPMGPKGPGQRGGLEGMKSGPGLLDSKLNRLGANTLQSMMS 488          

Query:  331 MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSF--VYFNIEKSH-LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNFLTSSNAAWVQNRRLAITG--KGPSLIDEKLQRLA 1776
            M+DA+NRVILNVGGIRHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYT+HR TQ+TL ILDR+D+DT++ +E +LYK+FG EEEF  N+L+FWQ+ +P++W++ +EPYSS+ AK+V+ + +  I+ISI+SFC+KT+PG  +P+I N T  +   G    S+ L +   +PHT F Y EC+CN+WF+ E+I R  VT   R F    +NIID  A LSFY+D+    V    E S+ ++EF SI+RIMRLFKLTRHI+GLKILI TFKASAKEL LLVFFL+VFI VFAALIYYAE+   N  N F SIP GLWWAI TMTTVGYGDM PKTY GMLVGALCA+TGVLTI+LPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPK + A               +R  + G   GP L+D KL RL 
Sbjct:    1 MSDADNRVILNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTSHRETQETLGILDRLDLDTDKLAEEDLYKKFGWEEEFLSNKLNFWQRIKPKLWALFDEPYSSMAAKIVAVVSVFFIVISILSFCLKTFPGLRVPIISNETVLIDENGS--TSFVLHKHRSEPHTAFLYIECVCNSWFTFEIITRFAVTPDKREFLKSPVNIIDFIATLSFYMDMVLNQVLSEEETSYEVLEFFSIIRIMRLFKLTRHIAGLKILIHTFKASAKELLLLVFFLIVFIVVFAALIYYAERIQYNPENSFDSIPIGLWWAIVTMTTVGYGDMAPKTYAGMLVGALCALTGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKSQSA------GPMGPKGPGQRGGLEGMKSGPGLLDSKLNRLG 479          

Query:  334 TDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRI-------DIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTV----FFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELN-------DFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPN 1674
            +D+E R+++N GG+RHETY++TLK +P TRLS LTE  A    +YDP  +E+FFDRHP VF+ ILNYYRTGKLH P DVCGPLFEEEL FWG+D   VE CCWM Y  HR  ++ L   +         D      ++ +L KR  L+E  ++ ++ +W+ W+PRIW++ E+PYSS  A+ V+   +  ILISI +FCM+T+  ++   I N T NV++G       +++++EI    V      Y E +C  WF+IE+  R++       FF  +LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+   N  +       +F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    R    G+PN
Sbjct:   33 SDSE-RIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKADEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFESPEPEAPDDDAALAGGADGDL-KRLCLQE--DNRKVGWWRVWQPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNT--IYNKTENVTVG-------NVTREEIVYEVVTDSWLTYVEGVCVVWFTIEVFTRVVFCPDKAEFFKSLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP----RAPQPGSPN 488          

Query:  334 TDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRI-------DIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTV----FFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELN-------DFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPN 1674
            +D+E R+++N GG+RHETY++TLK +P TRLS LTE  A    +YDP  +E+FFDRHP VF+ ILNYYRTGKLH P DVCGPLFEEEL FWG+D   VE CCWM Y  HR  ++ L   +         D      ++ +L KR  L+E  ++ ++ +W+ W+PRIW++ E+PYSS  A+ V+   +  ILISI +FCM+T+  ++   I N T NV++G       +++++EI    V      Y E +C  WF+IE+  R++       FF  +LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+   N  +       +F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    R    G+PN
Sbjct:   33 SDSE-RIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKADEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFESPEPEAPDDDAALAGGADGDL-KRLCLQE--DNRKVGWWRVWQPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNT--IYNKTENVTVG-------NVTREEIVYEVVTDSWLTYVEGVCVVWFTIEVFTRVVFCPDKAEFFKSLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP----RAPQPGSPN 488          

Query:  334 TDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRI-------DIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTV----FFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELN-------DFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPN 1674
            +D+E R+++N GG+RHETY++TLK +P TRLS LTE  A    +YDP  +E+FFDRHP VF+ ILNYYRTGKLH P DVCGPLFEEEL FWG+D   VE CCWM Y  HR  ++ L   +         D      ++ +L KR  L+E  ++ ++ +W+ W+PRIW++ E+PYSS  A+ V+   +  ILISI +FCM+T+  ++   I N T NV++G       +++++EI    V      Y E +C  WF+IE+  R++       FF  +LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+   N  +       +F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    R    G+PN
Sbjct:    5 SDSE-RIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKADEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFESPEPEAPDDDAALAGGADGDL-KRLCLQE--DNRKVGWWRVWQPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNT--IYNKTENVTVG-------NVTREEIVYEVVTDSWLTYVEGVCVVWFTIEVFTRVVFCPDKAEFFKSLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP----RAPQPGSPN 460          

Query:  334 TDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRI-------DIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTV----FFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELN-------DFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPN 1674
            +D+E R+++N GG+RHETY++TLK +P TRLS LTE  A    +YDP  +E+FFDRHP VF+ ILNYYRTGKLH P DVCGPLFEEEL FWG+D   VE CCWM Y  HR  ++ L   +         D      ++ +L KR  L+E  ++ ++ +W+ W+PRIW++ E+PYSS  A+ V+   +  ILISI +FCM+T+  ++   I N T NV++G       +++++EI    V      Y E +C  WF+IE+  R++       FF  +LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+   N  +       +F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    R    G+PN
Sbjct:   33 SDSE-RIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKADEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFESPEPEAPDDDAALAGGADGDL-KRLCLQE--DNRKVGWWRVWQPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNT--IYNKTENVTVG-------NVTREEIVYEVVTDSWLTYVEGVCVVWFTIEVFTRVVFCPDKAEFFKSLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP----RAPQPGSPN 488          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDR--IDIDTERT------------SESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNI-EKSHLIEFMSI---LRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFT-------KNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            D ++RV++NVGGIRH+TY++TL+ +P TRL+ L E  A    +YD  ++E+FFDRHPGVFA ILNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY  HR  ++ L        ++  + T             E E+ KR  L +  +      WQ+W+ R+W++ E+PYSS  A+ V+   +  IL+SI +FC++T+  ++   I+N T       D   + +   +E +      Y E +C  WF+ E ++R+      + F  + LNIID  A+L FY++V     +  E   ++ F+ +   +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+          +E   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DEKDRVVINVGGIRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDAQIDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGPAELGNDDTDADGLGDPGDGDEELEMTKRLALGDAPDGKAGGLWQRWQRRVWALFEDPYSSKYARWVAFASLFFILVSITTFCLETHEAFNP--IINRT-----DIDPVDNSTRIYQETETEVFLTYIEGVCVVWFTFEFLMRVTFCPDKKKFIKNTLNIIDFVAILPFYLEVGLSGLSSKEAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAKPNDPRASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 446          

Query:  334 TDAENRVILNVGGIRHETYKATLKKIPATRLSKLTE--ALAN--YDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDI--DTERTSESELYKRFGLEEEFED-NELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQA 1596
            +D   RV++NVGG RHETY+ TL+ +P TRLS LTE  A AN  YD   NE+FFDRHP VFA ILNYYRTGKLH P++VCGPLFEEEL FWG+D   VEPCCWM Y  HR  ++ L   +  DI  + E   + E+ KRFGL+E   D  +L F ++W+PR+W++ E+PYSS  A++V+   +  ILISI +FC++T+  ++   +LN T N +I     Q   +   +++   V  Y E +C AWFS E ++R+I     + F  + LN+ID  A+L FY++V       + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +I+YAE+F       T ++   F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NFSM+YS   A
Sbjct:   32 SDENERVVINVGGTRHETYRGTLRTLPGTRLSWLTEPDAFANFDYDAKGNEFFFDRHPTVFAHILNYYRTGKLHCPSEVCGPLFEEELIFWGIDETDVEPCCWMNYRQHRDAEEALVSFENPDINGNDEVNEDGEVSKRFGLDERSPDGGKLGFLRRWQPRMWALFEDPYSSRAARIVALASLLFILISITTFCLETHEAFNT--VLNKTENYTINNVTTQKVYV---DVETDPVLMYVEGVCVAWFSFEFLVRIICCPDKKVFIKNYLNVIDFVAILPFYLEVGLSSLTSKPARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIFYAERFGANPNDPTASDHTSFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFSMYYSLAMA 465          

Query:  349 RVILNVGGIRHETYKATLKKIPATRLSKL---------TEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFV--------YFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKR 1620
            RV LNVGG+ HE    TL+++P TRL +L         +E   +Y    NEYFFDRHPG FA +LN+YRTG+LH   ++C   F +EL++WG+D   +E CC   Y      Q   Q+ + +  + E   E E        +EFE    +     R ++W +LE P SS+ AK ++ + I  I++S I+  + T P       L H    S    +  +  L+Q            E +C AWF++E +LR +   +   FF   LN+ID+ A+L +YI +           + N+ +  +++   I+RI+R+ KL RH +GL+ L  T + S  EL LL+ FL + I +F++L+++AEK   +    F SIP   WWA  TMTTVGYGD+ P T  G ++G LC + GVL I+LP+P+IV+NFS FY   + + K  K+R
Sbjct:    1 RVRLNVGGLVHEVLWRTLERLPRTRLGRLHATNTHGALSELCDDYSIADNEYFFDRHPGAFASVLNFYRTGRLHMSEEMCALSFGQELDYWGVDEIYLETCCQARY-----HQKKEQMSEELRREAESARERE-------GDEFEGTCCA---DKRRKLWELLENPNSSLAAKGMAIVSILFIVLSTIALSLNTLPD------LQHKDEFS---HIIDNPKLAQ-----------VEAVCIAWFTMEYLLRFMSAPNKWKFFKGALNVIDLMAILPYYITIFLTESSRGVSQFQNVRR--VVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEPD--TKFHSIPASFWWATITMTTVGYGDIYPMTLLGKIIGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAVKRR 402          

Query:  328 KMTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTG-KLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIE---KSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYS 1584
            K    +NRV++NV G R ET   TL + P + L    +    +DP+ NEYFFDR    F  IL YY++G +L  P DV   +F EE+EF+ L    V           +  ++TL        DT              EE     +      ++  +W + E    S+ AK++S +     ++SI   C++T P +           V      F S   S   + P   FF  E  C  WF  EL +R     S  SF  D +N IDI A++ ++I V       +   +  L++ + ++R++R+FKL+RH   L+IL LT KAS +EL++L FFL V + +F+  IYY E    +    F+SIP+  WWA+ TMT VGYGDM P T  G +VGALCA+TGVLTISLPVPVIVSNF  FY+
Sbjct:    3 KQLTCDNRVVINVSGERFETQLKTLDQFPDSLLGHPDKRARYFDPLQNEYFFDRSHVNFDAILFYYQSGGRLCKPVDVPSDVFREEVEFYELGEEAVA----------KYGENTL--------DTPE------------EENVHGKD------FQQHVWRLFESRDGSIAAKMLSLMSFVTTILSITVMCLETLPQF------RKDNQVHANRTEF-SIRTSIYNLDP---FFMLETACVVWFIFELAVRFYACPSKTSFMKDFMNAIDILAIMPYFITVVLEIMQQQDQTRQPLLKIIRLVRVLRIFKLSRHCQDLQILGLTLKASLRELAMLSFFLFVAVVIFSGAIYYVE--ADDPQKHFSSIPDAFWWAVVTMTLVGYGDMWPMTVGGKIVGALCAITGVLTISLPVPVIVSNFKYFYN 377          

Query:  346 NRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTG-KLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIE---KSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYS 1584
             RV++NV G R ET   TL + P + L    +    +DP+ NEYFFDR    F  IL YY++G +L  P DV   +F EE+EF+ L    V           +  ++TL        DT              EE     +      ++  +W + E    S+ AK++S +     ++SI   C++T P +           V      F S   S   + P   FF  E  C  WF  EL +R     S  SF  D +N IDI A++ ++I V       +   +  L++ + ++R++R+FKL+RH   L+IL LT KAS +EL++L FFL V + +F+  IYY E    +    F+SIP+  WWA+ TMT VGYGDM P T  G +VGALCA+TGVLTISLPVPVIVSNF  FY+
Sbjct:    1 QRVVINVSGERFETQLKTLDQFPDSLLGHPDKRARYFDPLQNEYFFDRSHVNFDAILFYYQSGGRLCKPVDVPSDVFREEVEFYELGEEAVA----------KYGENTL--------DTPE------------EENVHGKD------FQQHVWRLFESRDGSIAAKMLSLMSFVTTILSITVMCLETLPQF------RKDNQVHANRTEF-SIRTSIYNLDP---FFMLETACVVWFIFELAVRFYACPSKTSFMKDFMNAIDILAIMPYFITVVLEIMQQQDQTRQPLLKIIRLVRVLRIFKLSRHCQDLQILGLTLKASLRELAMLSFFLFVAVVIFSGAIYYVE--ADDPQKHFSSIPDAFWWAVVTMTLVGYGDMWPMTVGGKIVGALCAITGVLTISLPVPVIVSNFKYFYN 369          

Query:  346 NRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTG-KLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIE---KSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYS 1584
             RV++NV G R ET   TL + P + L    +    +DP+ NEYFFDR    F  IL YY++G +L  P DV   +F EE+EF+ L    V           +  ++TL        DT              EE     +      ++  +W + E    S+ AK++S +     ++SI   C++T P +           V      F S   S   + P   FF  E  C  WF  EL +R     S  SF  D +N IDI A++ ++I V       +   +  L++ + ++R++R+FKL+RH   L+IL LT KAS +EL++L FFL V + +F+  IYY E    +    F+SIP+  WWA+ TMT VGYGDM P T  G +VGALCA+TGVLTISLPVPVIVSNF  FY+
Sbjct:    5 QRVVINVSGERFETQLKTLDQFPDSLLGHPDKRARYFDPLQNEYFFDRSHVNFDAILFYYQSGGRLCKPVDVPSDVFREEVEFYELGEEAVA----------KYGENTL--------DTPE------------EENVHGKD------FQQHVWRLFESRDGSIAAKMLSLMSFVTTILSITVMCLETLPQF------RKDNQVHANRTEF-SIRTSIYNLDP---FFMLETACVVWFIFELAVRFYACPSKTSFMKDFMNAIDILAIMPYFITVVLEIMQQQDQTRQPLLKIIRLVRVLRIFKLSRHCQDLQILGLTLKASLRELAMLSFFLFVAVVIFSGAIYYVE--ADDPQKHFSSIPDAFWWAVVTMTLVGYGDMWPMTVGGKIVGALCAITGVLTISLPVPVIVSNFKYFYN 373          

Query:  328 KMTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTE---ALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRR 1623
            + T+A +RV++NVGG +HETY  TLK IP TRL  +TE    L  +DP  +E+FFDRHPGVFAQ+LN+YRTGKLH P DVCGPLFE+EL FWG+D  QVEPCCW+ Y  HR  Q  L   D  D D E   + ++     + +       ++W+K++PRIW++ EEPYSS+ A++++ I + +I+ S+  FC++T P +  P                        +     V +  E +C AWF++E + R+I      SFF   +N ID+ A+L FY+ +     N +   ++  + ++R+ R+FKL+RH  GL+IL  T ++S  EL LLVFFL + + +F+++I+YAEK TK     FT+IP+  WWA+ TMTT+GYGDMVP T+ G +VG+LCAV GVL I+LPVPVIVSNFS++YSH +AR KLP+++R
Sbjct:   10 EQTNAGDRVVINVGGQKHETYIGTLKNIPDTRLYWITENGTQLPEFDPNTSEFFFDRHPGVFAQVLNFYRTGKLHCPNDVCGPLFEDELAFWGIDELQVEPCCWLNYKQHREAQANLDPFDHHDSDNESVGDMDMSVYGLVADSIRQRNRTWWKKYQPRIWTMFEEPYSSIPAQVLAFITMFLIISSVCLFCLETVPKFDNP------------------------KTSEGFVLYILEAVCVAWFTLEFLFRLIFCPDKLSFFKKPMNWIDLGAILPFYLTLIVRESNFKTIVVLRVVRLIRVFRIFKLSRHSYGLQILGHTLRSSCSELFLLVFFLTIGVVIFSSVIFYAEKDTKG--THFTTIPHTFWWAVVTMTTLGYGDMVPITWQGQIVGSLCAVCGVLMIALPVPVIVSNFSLYYSHAKARMKLPRRKR 418          

Query:  346 NRVILNVGGIRHETYKATLKKIPATRLSKLTEA---LANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESEL-YKRFGLEEEFE-DNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRR 1626
            +RV +NVGG+RHETYK+TLK IP TRLS + EA    A++DP   EYFFDRHPGVFA +LNYYRTGKLH P DVCGPLFE+EL FWG+D  QVE CCW+TY  HR  Q+TL   + ++ + E   + E    R+G     E + + ++W++++PRIW+++EEP+SS LAK+++   +++IL+S+  FC+++   +                        S+K ++   V    E IC  WF++EL++R +   +   FF  ++N ID  A++ FY+ + F   N +   L+  + ++RI R+FKL+RH SGL+IL  T +AS +EL LL+FFL++ + +FA+LI+Y EK  K     F  IP+  WWA+ TMTTVGYGDM P++  G  +G+LCAV GVLTI+LPVPVIV+NFS++YSH QAR KLPKKRRR
Sbjct:    1 DRVSINVGGVRHETYKSTLKNIPDTRLSWIAEASAGAADFDPSTGEYFFDRHPGVFANVLNYYRTGKLHCPLDVCGPLFEDELGFWGIDDQQVESCCWLTYRQHRDAQETLAAFEGVEFENEYEDDEEPDLGRYGFNFAAESEPDKTWWERYQPRIWTLMEEPHSSTLAKVIAYTTLTLILVSVGIFCLESMEKF------------------------SEKYLKDLLVIL--EGICVVWFTLELMVRFVFCPAKCEFFKKIMNWIDFLAIVPFYVSLGFNNNNNDIDALMI-IRLIRIFRIFKLSRHSSGLQILGHTLRASFRELLLLIFFLLIGVVLFASLIFYCEK--KIPGTKFVDIPSSFWWAVVTMTTVGYGDMAPQSPSGKFIGSLCAVCGVLTIALPVPVIVNNFSLYYSHAQARLKLPKKRRR 403          

Query:  325 SKMTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRR 1626
            +K+ D+ +R+I+NVGG RHET  +TL+ IP TRLS + E     +    EYFFDRHP  F Q+LN+YRTGKLH PT++CGP+FEEEL FWG+D  Q+EPCCW TYT HR  ++ L+       +  +   +E +    +      NEL+ W++ +P++W  L+EP+SS +AK+ S      I +SI +FC  T P     +  N+      G D                   + E  C+ +FS EL +R+I   S   F   ++N ID  A++ FY+++ +       + ++    ++RIMRLF+  +   GL+I+I T KAS+ EL LL+  +++ + +F++++YY E   +     FTS+P   WW + TMTTVGYGDM P+T+PG ++G  CA+ GVL ++LP+ VI SNF+++Y+H QAR KLP K+RR
Sbjct:   10 TKIADS-SRIIINVGGFRHETSVSTLQNIPDTRLSWIAENSTVNEDNKREYFFDRHPTAFCQVLNFYRTGKLHCPTEMCGPMFEEELIFWGIDEKQMEPCCWGTYTQHREAEENLKAFVGPGFNDLKDEPAENH----MGSYGSINELNCWKRIQPQLWETLDEPHSSKMAKIFSYTSCLFIALSIATFCATTMPA----IRKNNIMGSREGLD-------------------HIEMFCSIFFSFELFMRLISCPSKLHFCRGIMNWIDFVAIIPFYVNIFY------PNPIVRMFLVIRIMRLFRFIKLSYGLQIMIQTLKASSHELVLLLLMVLIPMVMFSSIVYYVEVIIEGRGAQFTSVPESFWWCLITMTTVGYGDMTPQTWPGKIIGGACAICGVLIVALPISVIGSNFNLYYAHAQARLKLPVKQRR 409          

Query:  340 AENRVILNVGGIRHETYKATLKKIPATRLSKLTE---ALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRH---ISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELN-------DFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRR 1626
             ++RVILNVGG RHETY +TL+ +P +RL+ + E     A+YDP  NE FFDRHPGVFA +LNYYRTGKLH P DVCGPLFEEEL FWG++  Q+EPCCW  YT HR  Q TL+  + +  DTE  SE E  +R    ++ +  +           W++LE+PYSS  A++++ + + II++S+ +FC+++ P                  D F      +KE Q   + +   C+   WF+ E + R I   S   F  + +  +D+ +++  YI  +      +    ++F+ +LR++R+F+L R    +SG++++  T +ASA+EL LLV  L++ + +F+ L++YAEK     LN       +F SIP+  WWAI TMTTVGYGD+ PKT  G  +G LCA  GVL ++LPV VI SNF++FYSH QA+ KLPKK+ +
Sbjct:    4 GKDRVILNVGGYRHETYLSTLRVVPDSRLAWIGENASKQADYDPETNEIFFDRHPGVFANVLNYYRTGKLHCPGDVCGPLFEEELAFWGIEELQMEPCCWSNYTQHRDAQATLKAFEGLQKDTE-DSEYEAGERLARRQKTKMQQF----------WALLEQPYSSKYAQILAMVSLVIIILSVTTFCIESMP----------------FADAF------KKEFQILEILY---CV---WFTFEFVARAIACPSKVEFIKNFMTWVDVLSIIPLYISFA------KGDQTLDFLFVLRLVRIFRLFRFFRTMSGMQVIGHTLRASARELFLLVLILLIPMVIFSTLVFYAEKSVSKFLNQRINSKGEFPSIPDAFWWAIITMTTVGYGDVTPKTPHGRFIGTLCACIGVLIVALPVSVIGSNFTLFYSHAQAQLKLPKKKHK 400          

Query:  343 ENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA---NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILD----RIDIDTERTSESELY-KRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRV 1629
            + R+ LNVGG +HETY +T++  P TRL  + E +    +Y     E FFDRHP +F Q+LNYYRTGKLH P DVCGPLFEEEL +WG+D  ++EPCCW TYT HR  +  L+  +      DID++R  E+E   K  GL          FW K++PRIW++LEEP SS  AK    + + +I++S+ + C  T P ++       + + +                  +  F   E IC  WF+IEL LR++   + R+FF      +D+ +++ FY+ + F +    +  L + + ++R++RLF+  R + GL++++ T KAS+ EL LL+  L++ + +F+++IYY EK    +   F SIP   WW++ TMTTVGYGDM P+T+ G ++G  CA+ GVL ++LP+ VI SNFS++Y+H QAR KLPKK+ ++
Sbjct:    9 QKRITLNVGGQKHETYLSTIRNYPDTRLYWVVENVTKAIDYHSEKIELFFDRHPKIFDQVLNYYRTGKLHCPNDVCGPLFEEELAYWGIDEKEMEPCCWTTYTQHREAEHNLKSFNVTDFSTDIDSDRQEETETTSKAKGLH--------PFWVKYQPRIWAILEEPRSSRTAKAFWILSVLLIVLSVATACAITLPQFATEGGSVSSESSA------------------YVAFTVIEYICGVWFTIELGLRLLFCPNKRTFFKSYSFWVDVLSVIPFYVRLIFPH----EHDLADALQVIRLLRLFRFFRLLYGLQVIMHTLKASSYELFLLLLILLIPVVLFSSIIYYVEKNIDGKTTKFRSIPESFWWSLITMTTVGYGDMTPRTWEGKIIGGACAIFGVLMVALPISVIGSNFSLYYAHAQARLKLPKKKTKI 415          

Query:  331 MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRI----------DIDTERTSE--SELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKN-------ELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPN 1674
            ++D ++R+++NVGGIRH+TY++TL+ +P TRLS L E  A    +YD  + E+FFDRHPGVFA ILNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY  HR  ++ L                D + E T +   E+ +R    +  +    S W +W+ R+W++ E+PYSS  A+ ++   +  IL+SI +FC++T+  ++   I+N TY   +     ++   + +E +      Y E +C  WF+ E ++R+    +   F  + LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+   N       +   F +IP G WWA+ TMTT+GYGDM PKT  GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ R +P    R    G+PN
Sbjct:    3 LSDDKDRIVINVGGIRHQTYRSTLRTLPGTRLSWLAEPDAPNHFDYDAKIEEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGGLLDLGSDDPDPEPEHTEDEVDEMTRRLAQGDSPDARSGSLWSRWQKRVWALFEDPYSSKYARWIALASLFFILVSITTFCLETHEAFNP--IVNRTYVEHLDNITTEN---TYQETETAAYLTYIEGVCVVWFTFEFLMRITFCPNKFDFIRNALNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASDHTQFKNIPIGFWWAVVTMTTLGYGDMYPKTTFGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNRHIP----RAPQPGSPN 468          

Query:  331 MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRI----------DIDTERTSE--SELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKN-------ELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPN 1674
            ++D ++R+++NVGGIRH+TY++TL+ +P TRLS L E  A    +YD  + E+FFDRHPGVFA ILNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY  HR  ++ L                D + E T +   E+ +R    +  +    S W +W+ R+W++ E+PYSS  A+ ++   +  IL+SI +FC++T+  ++   I+N TY   +     ++   + +E +      Y E +C  WF+ E ++R+    +   F  + LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+   N       +   F +IP G WWA+ TMTT+GYGDM PKT  GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ R +P    R    G+PN
Sbjct:    3 LSDDKDRIVINVGGIRHQTYRSTLRTLPGTRLSWLAEPDAPNHFDYDAKIEEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGGLLDLGSDDPDPEPEHTEDEVDEMTRRLAQGDSPDARSGSLWSRWQKRVWALFEDPYSSKYARWIALASLFFILVSITTFCLETHEAFNP--IVNRTYVEHLDNITTEN---TYQETETAAYLTYIEGVCVVWFTFEFLMRITFCPNKFDFIRNALNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASDHTQFKNIPIGFWWAVVTMTTLGYGDMYPKTTFGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNRHIP----RAPQPGSPN 468          

Query:  322 CSKMTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTER-------TSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTV----FFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH-LIEFMSI---LRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELND--------FTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNFLTSSNA-AWVQNRRLAITGKGPSLI 1752
            CS  +D+E ++++N GGIRHETY++TLK +P TRLS LTE  A    +YDP  +E+FFDRHP  FA ILNYYRTGKLH P+DVCGPLFEEEL FWG+D   VE CCWM Y  HR  ++ L   +  + D           ++ +L KR  ++E  +    + WQ W+P +W++ E+PYSS  A+ V+   +  IL+SI +FC++T+  ++   I N T NV++G       + + +EI    V      Y E +C  WF+IE++ R+I       FF   LNIID  A++ FY++V+    + + +  ++ F+ +   +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+   +  ND        F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKKR + +P    R    G+PN     + A A     RL     GP ++
Sbjct:    3 CSA-SDSE-KIVINCGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPATFAFILNYYRTGKLHCPSDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPDAPEDDPALTGCADGDL-KRLCMQE--DGRRATRWQVWQPWMWALFEDPYSSKYARYVAFASLFFILLSISTFCLETHEAFNT--IYNKTENVTVG-------NFTHEEIVYEVVTDGWLTYVEGVCVIWFTIEVMARVIFCPDKAEFFRSALNIIDFVAIVPFYLEVALSGLSSKTAKDILSFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADP-NDPTAAAHTTFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRNKHIP----RAPQPGSPNYCKPDALAMATASPHRLMGNVIGPGMV 488          

Query:  349 RVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQ--------------ILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTV----FFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPN 1674
            ++++N GG+RHETY++TLK +P TRLS LTE  A    +YDP L+E+FFDRHP VF+ ILNYYRTGKLH P DVCGPLFEEEL FWG+D   VE CCWM Y  HR  ++ L                L   D D +R    E  +R G           +W+ W+PRIW++ E+PYSS  A+ V+ + +  ILISI +FCM+T+  ++   I N T NV+IG       +++++EI    V      Y E +C  WF+IE++LR+        FF   LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        T +   +F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    R    G+PN
Sbjct:    9 KIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKLDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPDAPDDDPALGGADGDLKRLCMQEDARRAG-----------WWKTWQPRIWALFEDPYSSKYARYVAFMSLFFILISISTFCMETHEAFNT--IYNKTENVTIG-------NVTREEIVYEVVTDSWLTYVEGVCVIWFTIEVLLRVTFCPDKLEFFKSALNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP----RAPQPGSPN 459          

Query:  349 RVILNVGGIRHETYKATLKKIPATRLSKLTEALA----NYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQ--------------ILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTV----FFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSH----LIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKF-------TKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPN 1674
            ++++N GG+RHETY++TLK +P TRLS LTE  A    +YDP L+E+FFDRHP VF+ ILNYYRTGKLH P DVCGPLFEEEL FWG+D   VE CCWM Y  HR  ++ L                L   D D +R    E  +R G           +W+ W+PRIW++ E+PYSS  A+ V+ + +  ILISI +FCM+T+  ++   I N T NV+IG       +++++EI    V      Y E +C  WF+IE++LR+        FF   LNIID  A+L FY++V     + + +      +  +  +RI+R+FKLTRH  GL++L  T +AS  E  LL+ FL + + +FA +IYYAE+        T +   +F +IP G WWA+ TMTT+GYGDM P+T+ GMLVGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    R    G+PN
Sbjct:   37 KIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKLDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPDAPDDDPALGGADGDLKRLCMQEDARRAG-----------WWKTWQPRIWALFEDPYSSKYARYVAFMSLFFILISISTFCMETHEAFNT--IYNKTENVTIG-------NVTREEIVYEVVTDSWLTYVEGVCVIWFTIEVLLRVTFCPDKLEFFKSALNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP----RAPQPGSPN 487          

Query:  331 MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNFLTSSNAAWVQNRRLAITGKGPSLIDEKLQRLALQQLIPMKSLAGNTNLGMALLNRSLIMNDKTSESGENLGLSELNNKPKNDTQFTYGRRAAVIDFSAVDMTPSSNKNSISTVNSVEENI 2040
            MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVSGIGISIILISIISFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSLLVFFLVVFIAVFAALIYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNFLTSSNAAWVQNRRLAITGKGPSLIDEKLQRLALQQLIPMKSLAGNTNLGMALLNRSLIMNDKTSESGENLGLSELNNKPKNDTQFTYGRRAAVIDFSAVDMTPSSNKNSISTVNSVEENI
Sbjct:    1 MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVSGIGISIILISIISFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSLLVFFLVVFIAVFAALIYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNFLTSSNAAWVQNRRLAITGKGPSLIDEKLQRLALQQLIPMKSLAGNTNLGMALLNRSLIMNDKTSESGENLGLSELNNKPKNDTQFTYGRRAAVIDFSAVDMTPSSNKNSISTVNSVEENI 570          

Query:  331 MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNFLTSSNAAWVQNRRLAITGKGPSLIDEKLQRLALQQLIPMKSLAGNTNLGMALLNRSLIMNDKTSESGENLGLSELNNKPKNDTQFTYGRRAAVIDFSAVDMTPSSNKNSISTVNSVEENI 2040
            MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVSGIGISIILISIISFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSLLVFFLVVFIAVFAALIYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNFLTSSNAAWVQNRRLAITGKGPSLIDEKLQRL          LAGNTNLGMALLNRSLIMNDKTSESGENLGLSELNNKPKNDTQFTYGRRAAVIDFSAVDMTPSSNKNSISTVNSVEENI
Sbjct:    1 MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVSGIGISIILISIISFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSLLVFFLVVFIAVFAALIYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNFLTSSNAAWVQNRRLAITGKGPSLIDEKLQRLG---------LAGNTNLGMALLNRSLIMNDKTSESGENLGLSELNNKPKNDTQFTYGRRAAVIDFSAVDMTPSSNKNSISTVNSVEENI 561          

Query:  331 MTDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDID-TERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILN---HTYNVSIGG--DLFQS--WSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKFKGAPNNFLTSSNAAWVQNRRLAITGKGPSLIDEKLQRLALQQLIPMKSLAGNTNLGMALLNRSLIMNDKTSESGENLGLSELNNKP-KNDTQFTYGRRAAVIDFSAVDMTPSSNKNSISTVNSVEENI 2040
            MTDA++RVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDP+LNEYFFDRHPGVF QILNYYR+GKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHR+TQ+TLQILDR+DID +ERT++ +LYK+FGLEEE+EDN+L+FWQ WRP IWS++EEPYS+ LAK +SG+ IS ILISI S C+KTY GY+IP+I+       +V + G  D F S  WS      +PH +F   E  CN WF+IE+ILR+ VT S   FF D LN IDI ALLSFYI+++F++F    + L+EF++I R+MRLFKLTRHISGLKILILTFKASAKELSLLVFFLVVFI VFAALIYYAE+FTKN  NDF SIPNGLWWA+ TMTTVGYGDMVPKTYPGMLVGALCA+TGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPK KG   + L+++      + RL  + +   +I         ++    KS       G+    R     D+ +        S+    P     + +YGRR AVID S++  +   ++ SI++ NS  E++
Sbjct:    1 MTDADHRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPILNEYFFDRHPGVFGQILNYYRSGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRNTQETLQILDRVDIDNSERTNDYDLYKKFGLEEEYEDNDLTFWQMWRPLIWSMMEEPYSTRLAKAISGLSISFILISITSLCLKTYSGYTIPIIVTMPIGNRSVYLDGLRDTFSSSVWSFQCLTRKPHHIFVLIEMGCNIWFTIEIILRLSVTPSLMKFFQDFLNFIDIVALLSFYIEIAFIWFRANSNQLVEFLAIFRVMRLFKLTRHISGLKILILTFKASAKELSLLVFFLVVFIVVFAALIYYAERFTKNPTNDFISIPNGLWWALVTMTTVGYGDMVPKTYPGMLVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKAKGINPSLLSNNTLTLPGHNRLPSSNR---IIYNYNFSANPEEPEANKSFPA----GVQFAKRGSSKEDRQNSVTNLDNESQSKRNPLTRQKKCSYGRRTAVIDISSIKSSDDEDEKSINSGNSSSEDV 572          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYF----NIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPK 1656
            D+ENRVILN+GG RHETYKATLKKIPATRLSKLTEALANYDP+LNEYFFDRHPGVF+Q+LNYYRTGKLHYPTDVCGPL+EEELEFWGLDSNQVEPCCWMTYT HRST++TLQIL+ IDIDT++ S+ +LY +FGLEE+ +  ++ +W+K + +IW++ E+PYSS  +K+V+ I +  I+ISI+SFC+KT   + IP    + +N+S+  +   SW++S+   Q H +F Y E ICN WF+IE+I+R +V  S   F    +NIID  ALLSFY+D+          +E   ++EF SI+RIMRLFKLTRHI+GL IL+ TF+AS KEL LLVFFL VFI +FAAL+YYAE+F  N  N F SIP GLWWAI TMTTVGYGDMVP TY GM VGALCA+TGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVE+VRPK
Sbjct:   51 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKIVAVITVFFIVISILSFCLKTASHFRIP----NLHNISVSDN--SSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKELVLLVFFLCVFIVIFAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPK 488          

Query:  337 DAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVXXXXXXXXXXXXXXFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYF----NIEKSHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSXXXXXXXXXXXXXXXXXYYAEKFTKNELNDFTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPK 1656
            D+ENRVILN+GG RHETYKATLKKIPATRLSKLTEALANYDP+LNEYFFDRHPGVF+Q+LNYYRTGKLHYPTDVCGPL+EEELEFWGLDSNQVEPCCWMTYT HRST++TLQIL+ IDIDT++ S+ +LY +FGLEE+ +  ++ +W+K + +IW++ E+PYSS  +K+V+ I +  I+ISI+SFC+KT   + IP    + +N+S+  +   SW++S+   Q H +F Y E ICN WF+IE+I+R +V  S   F    +NIID  ALLSFY+D+          +E   ++EF SI+RIMRLFKLTRHI+GL IL+ TF+AS KEL LLVFFL VFI +FAAL+YYAE+F  N  N F SIP GLWWAI TMTTVGYGDMVP TY GM VGALCA+TGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVE+VRPK
Sbjct:   61 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKIVAVITVFFIVISILSFCLKTASHFRIP----NLHNISVSDN--SSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKELVLLVFFLCVFIVIFAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPK 498