Tetratricopeptide repeat domain 17
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002880 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Human
Match: TTC17 (tetratricopeptide repeat domain 17 [Source:HGNC Symbol;Acc:HGNC:25596]) HSP 1 Score: 140.198 bits (352), Expect = 5.979e-33 Identity = 102/348 (29.31%), Postives = 181/348 (52.01%), Query Frame = 1
Query: 133 THWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEG--VPEISLYKIAMPQHLTPT--EYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
THW VT+ G I+ S +L+ P +LV L++QE + +++ +E +L ++ N++ + + + + C+KA L + L+ ++LE+K I DY++ + + + +QP C +S+ F+HL ++ R L +P+ + + L + + GHL+ L + ++ +W+LYNMA+FYWR+K +EC ALH S +DIALV+LAN+ H S DA V++ A+ S FTS++ LGNIYA LG++N+S+ Y A + IK R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 40 THWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQEATVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDISPEDYIDTE--SPVPPDP-EQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQK----NTSSWVLYNMASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAH-FSADAAVVVHAALDDSDFFTSYY-TLGNIYAMLGEYNHSVLCYDHALQARPGFEQAIK------RKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHY 372 HSP 2 Score: 88.5817 bits (218), Expect = 5.500e-17 Identity = 46/123 (37.40%), Postives = 71/123 (57.72%), Query Frame = 1
Query: 1765 RSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
++ + H + LL + + E+IG + AI + W++ N AGLYWR VGN A+ C + ++ L+P++Y+DVPLVNLA +LI + + DA KL+ A I+ SEP T + N Y
Sbjct: 577 KAKMPDDHARKILLSRINNYTIPEEEIGSFLFHAINKPNAPIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVNLANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAY 699 HSP 3 Score: 78.9518 bits (193), Expect = 4.089e-14 Identity = 44/149 (29.53%), Postives = 82/149 (55.03%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
S++DIG ++ G+++N + W + ++ YWR+ + Q C A+ S ++ + LVN AN+L+R + A + H +L D ++ + + NI+A + ++N + L Y+ L + FE+A+ R ++ CQQ + Q LE QH
Sbjct: 207 SIDDIGHLIHEGLQKNTSSWVLYNMASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAAL---DDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQARPGFEQAIKRKHAVLCQQKLEQKLEAQH 352 HSP 4 Score: 67.0106 bits (162), Expect = 1.905e-10 Identity = 36/101 (35.64%), Postives = 57/101 (56.44%), Query Frame = 1
Query: 700 WILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL 1002
W++ N A YWR G++ AI CL+ AL+ +P +YQD+ LV+LAN+ + LDA L+ A+ I+ + LGN Y +L + +L ++ A L
Sbjct: 619 WLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVNLANLL-IHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKL 718
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Human
Match: TTC17 (tetratricopeptide repeat domain 17 [Source:HGNC Symbol;Acc:HGNC:25596]) HSP 1 Score: 139.043 bits (349), Expect = 1.884e-32 Identity = 102/348 (29.31%), Postives = 180/348 (51.72%), Query Frame = 1
Query: 133 THWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEG--VPEISLYKIAMPQHLTPT--EYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
THW VT+ G I+ S +L+ P +LV L++QE + +++ +E +L ++ N++ + + + + C+KA L + L+ ++LE+K I DY++ + + + +QP C +S+ F+HL ++ R L +P+ + + L + + GHL+ L ++ +W+LYNMA+FYWR+K +EC ALH S +DIALV+LAN+ H S DA V++ A+ S FTS++ LGNIYA LG++N+S+ Y A + IK R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 40 THWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQEATVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDISPEDYIDTE--SPVPPDP-EQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGL----QKNTSSWVLYNMASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAH-FSADAAVVVHAALDDSDFFTSYY-TLGNIYAMLGEYNHSVLCYDHALQARPGFEQAIK------RKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHY 372 HSP 2 Score: 119.013 bits (297), Expect = 2.725e-26 Identity = 82/287 (28.57%), Postives = 142/287 (49.48%), Query Frame = 1
Query: 190 HLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNF--SMCCFEHLETIRNRSMLEGVPEISLYKIA--MPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
H + P V+ Q E + +E+ +V++ Q + + S C+K + E T + L++ +K I ++++ A +QQP E N N SM +HL + NR+ L E L ++ + + P + + + + + + +W+L +MAA YWRVKG K AI+CLR ALH +P + +D+ L+SLANI H K + DA+++ A+ I+PHF +H LGN+Y ++ +F +L Y+ L + P K++I+
Sbjct: 852 HKKTPGKKVETGQIENGHRYQANLEITGPKVASP--GPQGKKRDYQRLGWPSPDECLKLRWV--ELTAIVSTWLAVSSKNIDITEHIDFA-------TPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWN-DAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQ 1126 HSP 3 Score: 90.8929 bits (224), Expect = 1.201e-17 Identity = 46/144 (31.94%), Postives = 85/144 (59.03%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQN 3579
SLE IG R+ +E+N T W +++++ YWRV G ++A +CL A+ +P + V L++ ANIL+ A+ + +++ + ++ V F + N++ ME++ KA ++YE+ L L+ +F A RI++IQC M+ +
Sbjct: 996 SLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEI--APHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKG 1137 HSP 4 Score: 88.1965 bits (217), Expect = 6.847e-17 Identity = 46/123 (37.40%), Postives = 71/123 (57.72%), Query Frame = 1
Query: 1765 RSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
++ + H + LL + + E+IG + AI + W++ N AGLYWR VGN A+ C + ++ L+P++Y+DVPLVNLA +LI + + DA KL+ A I+ SEP T + N Y
Sbjct: 577 KAKMPDDHARKILLSRINNYTIPEEEIGSFLFHAINKPNAPIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVNLANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAY 699 HSP 5 Score: 78.5666 bits (192), Expect = 7.452e-14 Identity = 44/149 (29.53%), Postives = 82/149 (55.03%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
S++DIG ++ G+++N + W + ++ YWR+ + Q C A+ S ++ + LVN AN+L+R + A + H +L D ++ + + NI+A + ++N + L Y+ L + FE+A+ R ++ CQQ + Q LE QH
Sbjct: 207 SIDDIGHLIHEGLQKNTSSWVLYNMASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAAL---DDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQARPGFEQAIKRKHAVLCQQKLEQKLEAQH 352 HSP 6 Score: 68.5514 bits (166), Expect = 7.038e-11 Identity = 52/172 (30.23%), Postives = 82/172 (47.67%), Query Frame = 1
Query: 1618 LTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
+T H + + P P N T + +D L + N S G S E +LQ L K Q LE IG RI +++ ++W+L ++A LYWR+ G +A+DC R ++ +P + +DVPL++LA IL + DA+ + A +I H N+Y
Sbjct: 930 ITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVS--NRASLHYTGESQLTE--VLQNLGK-DQYPQQSLEQIGTRIAKVLEKN-QTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVY 1095 HSP 7 Score: 66.2402 bits (160), Expect = 3.581e-10 Identity = 36/101 (35.64%), Postives = 57/101 (56.44%), Query Frame = 1
Query: 700 WILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL 1002
W++ N A YWR G++ AI CL+ AL+ +P +YQD+ LV+LAN+ + LDA L+ A+ I+ + LGN Y +L + +L ++ A L
Sbjct: 619 WLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVNLANLL-IHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKL 718
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Human
Match: TTC17 (tetratricopeptide repeat domain 17 [Source:HGNC Symbol;Acc:HGNC:25596]) HSP 1 Score: 105.531 bits (262), Expect = 2.018e-25 Identity = 51/126 (40.48%), Postives = 80/126 (63.49%), Query Frame = 1
Query: 661 SSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
+ LG + + +W+L +MAA YWRVKG K AI+CLR ALH +P + +D+ L+SLANI H K + DA+++ A+ I+PHF +H LGN+Y ++ +F +L Y+ L + P K++I+
Sbjct: 33 AGLGMYPYQNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWN-DAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQ 157 HSP 2 Score: 81.6481 bits (200), Expect = 5.185e-17 Identity = 49/162 (30.25%), Postives = 88/162 (54.32%), Query Frame = 1
Query: 3139 DRY---SLEDIGKRLYTGIE------------QNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQN 3579
D+Y SLE IG R+ +E QN T W +++++ YWRV G ++A +CL A+ +P + V L++ ANIL+ A+ + +++ + ++ V F + N++ ME++ KA ++YE+ L L+ +F A RI++IQC M+ +
Sbjct: 9 DQYPQQSLEQIGTRIAKVLEKASTAGLGMYPYQNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEI--APHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKG 168 HSP 3 Score: 59.6918 bits (143), Expect = 2.101e-9 Identity = 34/111 (30.63%), Postives = 58/111 (52.25%), Query Frame = 1
Query: 1834 LEDIGQRIVTAIKR-----------RLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
LE IG RI +++ + ++W+L ++A LYWR+ G +A+DC R ++ +P + +DVPL++LA IL + DA+ + A +I H N+Y
Sbjct: 16 LEQIGTRIAKVLEKASTAGLGMYPYQNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVY 126
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Celegans
Match: ttc-17 (TeTratriCopeptide repeat domain protein related [Source:UniProtKB/TrEMBL;Acc:Q22554]) HSP 1 Score: 98.9821 bits (245), Expect = 1.397e-20 Identity = 54/131 (41.22%), Postives = 78/131 (59.54%), Query Frame = 1
Query: 646 GHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
L A+ L + D +W+L +++ YWRV G+A++AI CLR ALHT+P +D+ALVSLANI H + A++ A+ SP + H LGNIYAS+G + +L+ Y SL + P KDKI+
Sbjct: 1139 ARLHAAMLHSNAKDGHVSWVLCVLSSLYWRVTGNAENAIGCLRCALHTAPPHMRDVALVSLANICHQAGLFN-SALISAGAALSASPRLVAIHFTLGNIYASIGDYQRALNFYYSTLSLQANFQPAKDKIR 1268 HSP 2 Score: 84.7297 bits (208), Expect = 3.292e-16 Identity = 51/159 (32.08%), Postives = 84/159 (52.83%), Query Frame = 1
Query: 3097 PEYNLHTSFLKTFDDRYSLEDIGKRLYTG-IEQNATD----WKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQC 3558
PE L + ++R ++E + RL+ + NA D W + +S YWRVTG+A+ A CL A+ +P V LV+ ANI ++ +AL +L S + I F + NI+A++ + +A FY + LSL+A+F+ A +I++I C
Sbjct: 1116 PEKALAEALKSLGNERDTIEHVAARLHAAMLHSNAKDGHVSWVLCVLSSLYWRVTGNAENAIGCLRCALHTAPPHMRDVALVSLANICHQAGLFNSALISAGAALSA--SPRLVAIHFTLGNIYASIGDYQRALNFYYSTLSLQANFQPAKDKIRTIYC 1272 HSP 3 Score: 78.1814 bits (191), Expect = 3.013e-14 Identity = 63/223 (28.25%), Postives = 102/223 (45.74%), Query Frame = 1
Query: 1576 KGFDLDNLLTTKQQLTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRN-QDAMKLIETAFK-IDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKC 2238
+G+ + LLTT L LPW+ P C ++V + DL +++E L + ++ +AEK L ++L V + ++ RI +K + W+ N+AGLYWRI GN QA C L L E V +V LA ++++ R DA + + YSEP H + + +++ A HL+ A+ ++ V DL I C
Sbjct: 609 RGWLVSELLTTHIGLQSADSLPLPWFEPRC-DFVKMDDLRVFSGFEAIERLLNPRF----DRKSEGYAEKTLKTTFVRLADRV-IEEHEMAARIQLLMKHTIGPRWVSLNLAGLYWRIQGNPHQATKC-LLGAFLDKPEESFVSIVQLAQVMLKSTRMVNDAHGFLNQQLNLLGYSEPLFHYVQGRMKLLLHDVDKAIQHLKDAMDKDPNNLVIQEDLLKIAC 824 HSP 4 Score: 50.8322 bits (120), Expect = 8.212e-6 Identity = 34/106 (32.08%), Postives = 50/106 (47.17%), Query Frame = 1
Query: 1732 SDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSN-------WILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAI 2028
SD + YQ + L E LK + +E + R+ A+ L SN W+L ++ LYWR+ GN A+ C R ++ +P RDV LV+LA I
Sbjct: 1108 SDQFLFYQ--------PEKALAEALKSLGNERDTIEHVAARLHAAM---LHSNAKDGHVSWVLCVLSSLYWRVTGNAENAIGCLRCALHTAPPHMRDVALVSLANI 1202
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Fly
Match: CG11436 (gene:FBgn0029713 transcript:FBtr0070699) HSP 1 Score: 86.2705 bits (212), Expect = 4.005e-17 Identity = 71/303 (23.43%), Postives = 132/303 (43.56%), Query Frame = 1
Query: 121 INGYTHWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKL----NQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEISLYKIAMPQH-----LTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL 1002
I HW + + ++ P S +H+R+P NL ++Q + E+++R L L Q+ L+ + + + +E A + E + I + K I D I + S ++ P C + + ++HLE+ R PE+ +H + E A QH+ S W + ++++YWR++G+A+ A+ C R A +P ++DI L+SL I + + DA +++ A+ +P+ +H++L + A FN SL H+ A L
Sbjct: 18 IQACNHWVLREEQIV-PKLDSPFHMREPHNLAAFLKQIRYSEYVERSYLDLLRKREQIVEHLRFSMRFGEDL------AEQAKCAMDYYMLEKRMSYLKITPEQLKRINLPDQRQLHIQKSASSMGME-PICSDYHRLSVGPATYDHLESFR--------PEVLAAAFLEREHDTNVGMATVELTRRFAVDGLQHHPAS---WKFHTLSSYYWRMRGNAREALPCARLAALLAPPIFKDIPLLSLGTILFRMGRLA-DADLILTAAVEHAPNVAENHVVLASALAMKHDFNRSLQHFDEAERL 300 HSP 2 Score: 60.8474 bits (146), Expect = 4.472e-9 Identity = 54/214 (25.23%), Postives = 94/214 (43.93%), Query Frame = 1
Query: 1600 LTTKQQLTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHL-EIAILQNSTLKVNNVDLDAIKC 2238
L ++QL + S P CS+Y ++ + P D LES + + L + F E+ + V M ++ +R + ++W ++ YWR+ GN +AL C RL+ L+P ++D+PL++L IL R R DA ++ A + + E H++ A+ ++ + H E L STL + I C
Sbjct: 120 LPDQRQLHIQKSASSMGMEPICSDYHRLS-VGPAT-YDHLESFRPEVLAA-------AFLER-------EHDTNVGMATVELTRRFAVDGLQHHPASWKFHTLSSYYWRMRGNAREALPCARLAALLAPPIFKDIPLLSLGTILFRMGRLADADLILTAAVEHAPNVAENHVVLASALAMKHDFNRSLQHFDEAERLDPSTLPRTQQVRNFISC 317 HSP 3 Score: 52.7582 bits (125), Expect = 1.820e-6 Identity = 29/102 (28.43%), Postives = 56/102 (54.90%), Query Frame = 1
Query: 3181 GIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKL-EAALEITHKSLQYPD-SQNWIVIPFLVANIFATMEQWNKA 3480
G++ + WK T+S YWR+ G+A++A C LA +P + + L++ IL+R+ +L +A L +T P+ ++N +V+ A+ A +N++
Sbjct: 193 GLQHHPASWKFHTLSSYYWRMRGNAREALPCARLAALLAPPIFKDIPLLSLGTILFRMGRLADADLILTAAVEHAPNVAENHVVL----ASALAMKHDFNRS 290
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Zebrafish
Match: ttc17 (tetratricopeptide repeat domain 17 [Source:NCBI gene;Acc:569538]) HSP 1 Score: 145.976 bits (367), Expect = 9.054e-35 Identity = 96/349 (27.51%), Postives = 184/349 (52.72%), Query Frame = 1
Query: 133 THWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEIS-----LYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
THW VT+ G I+ S +L+ P +LV +QQE + +++++E +L ++ N++ + + + ++ CV A L + L+ +SLE+K I +L+ L + L++P C + +S+ F+HL ++ + L P +S + + + E GH + +L + +S +W+LYN+A+FYWR+K + A++C+ ALH SP +++D+ALV++AN+ H ++ AI+ L + TSH+ LGNIYA LG++N+S+ Y+ A + ++ R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 57 THWVVTEDGKIQQQVDSPLNLKHPHHLVLFMQQETRVNYLKKLEKQLVAQKIHIEENEDRDTGLEQRHYKEDADCVTAKVPLGDLDLYDGTFISLESKDINPEQFLD---LMSALPPDLEKPDCAKLLDLPYSIHAFQHLRGVQEKVNLTS-PLLSKDDPIFTSLCLKLGQSVDEVGHRIHQALLK----NSSSWVLYNLASFYWRIKNEPRRAVDCVVRALHFSPRQHKDVALVNMANVLHRAHFSADAAILAHAALDLTTDLLTSHY-TLGNIYAMLGEYNHSVLCYEQALQAQPGFEQALR------RKHAVLCQQKLEQRLEAQHRSLQRTLNELKEYQKQHDHY 390 HSP 2 Score: 117.472 bits (293), Expect = 4.482e-26 Identity = 67/214 (31.31%), Postives = 114/214 (53.27%), Query Frame = 1
Query: 409 LSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNF--SMCCFEHLETIRNRSMLEGVPEISLYKIA--MPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
L++ AK I ++++ A LQ+P E N N SM +HL + NR + E L ++ + + P++ V + + + + +W+L +MAA YWRVKG K AI+CLR AL+ +P +D+ L+SLANIF + DA+ + + A+ I+PHF +H L N+Y ++ +F ++H Y+ L + P KD+++
Sbjct: 978 LAVSAKNIDITEHIDFA-------TPLQEPAVEPVCNANLPASMHTLDHLSGVANRGGIHYTGESQLREVLQNLGKDKFPSQSFEQVGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKRAIDCLRQALNYAPHHMKDVPLISLANIFQNARLWE-DALTVARMAVEIAPHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFGPAKDRLR 1183 HSP 3 Score: 96.6709 bits (239), Expect = 1.365e-19 Identity = 63/241 (26.14%), Postives = 117/241 (48.55%), Query Frame = 1
Query: 2863 APEDCEHVAPFDFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCT---PKGT---NFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRY---SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQC 3558
PE+C+ D T +++++ I++ +D TP L P C P + L + ++ I Y+ E L D++ S E +G R+ +E+N T W +++++ YWRV G ++A +CL A+ +P + V L++ ANI E AL + +++ + +++V F +AN++ ME++ KA +YE+ L L+ +F A R+++IQC
Sbjct: 958 GPEECQRTRRVDLTTVASTWLAVSAKNIDITEHIDFATP--LQEPAVEPVCNANLPASMHTLDHLSGVANRGGI-----HYTG--ESQLREVLQNLGKDKFPSQSFEQVGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKRAIDCLRQALNYAPHHMKDVPLISLANIFQNARLWEDALTVARMAVEI--APHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFGPAKDRLRTIQC 1187 HSP 4 Score: 80.8777 bits (198), Expect = 7.420e-15 Identity = 43/149 (28.86%), Postives = 84/149 (56.38%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
S++++G R++ + +N++ W + ++ YWR+ + ++A +C+ A+ SP H+ V LVN AN+L+R + +A + + + + + NI+A + ++N + L YE L + FE+A+ R ++ CQQ + Q LE QH
Sbjct: 224 SVDEVGHRIHQALLKNSSSWVLYNLASFYWRIKNEPRRAVDCVVRALHFSPRQHKDVALVNMANVLHRAHF--SADAAILAHAALDLTTDLLTSHYTLGNIYAMLGEYNHSVLCYEQALQAQPGFEQALRRKHAVLCQQKLEQRLEAQH 370 HSP 5 Score: 78.5666 bits (192), Expect = 4.010e-14 Identity = 43/120 (35.83%), Postives = 69/120 (57.50%), Query Frame = 1
Query: 1801 LLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLA 2160
LLK G + LE G I A+++ W++ N AGL+WR GN QAL C R ++ +P ++RD+PLVN A +L+ + + +A +L++ A +I+ SEP T + N++ L A
Sbjct: 602 LLKRSGGRS--LEQTGALIAQALEKMSGPRWMMQNEAGLFWRAKGNGTQALVCLRQALHSAPPQHRDLPLVNTANLLLHYGLHSEAHELLQQALQINQSEPHTLLSLVNVHLSQGNLTGA 719 HSP 6 Score: 71.2478 bits (173), Expect = 6.479e-12 Identity = 47/173 (27.17%), Postives = 84/173 (48.55%), Query Frame = 1
Query: 1735 DNLISYQNKGRSNFAEKHLLQELLKLV---QGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKL 2244
D+L N+G ++ + L+E+L+ + + + E +G RI +++ ++W+L ++A LYWR+ G +A+DC R ++ +P +DVPL++LA I + +DA+ + A +I H AN+Y E A H E + L I+C L
Sbjct: 1018 DHLSGVANRGGIHYTGESQLREVLQNLGKDKFPSQSFEQVGTRIAKVLEKN-QTSWVLSSMAALYWRVKGQGKRAIDCLRQALNYAPHHMKDVPLISLANIFQNARLWEDALTVARMAVEIAPHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFGPAKDRLRTIQCYL 1189 HSP 7 Score: 63.1586 bits (152), Expect = 1.905e-9 Identity = 38/117 (32.48%), Postives = 64/117 (54.70%), Query Frame = 1
Query: 646 GHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILIS---PH----FTSHHMILGNIYASLGQFNNSL 975
G L+A +L + S W++ N A +WR KG+ A+ CLR ALH++P +++D+ LV+ AN+ L +A L++ A+ I+ PH + H+ GN+ +L F +L
Sbjct: 615 GALIAQALEKM---SGPRWMMQNEAGLFWRAKGNGTQALVCLRQALHSAPPQHRDLPLVNTANLL-LHYGLHSEAHELLQQALQINQSEPHTLLSLVNVHLSQGNLTGALAVFRQAL 727 HSP 8 Score: 59.3066 bits (142), Expect = 3.504e-8 Identity = 31/78 (39.74%), Postives = 49/78 (62.82%), Query Frame = 1
Query: 1804 LKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIR 2037
LKL Q V+ ++G RI A+ + S+W+L+N+A YWRI +A+DC ++ SP +++DV LVN+A +L R
Sbjct: 219 LKLGQSVD----EVGHRIHQALLKN-SSSWVLYNLASFYWRIKNEPRRAVDCVVRALHFSPRQHKDVALVNMANVLHR 291
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Xenopus
Match: lpar1 (lysophosphatidic acid receptor 1 [Source:Xenbase;Acc:XB-GENE-958415]) HSP 1 Score: 163.31 bits (412), Expect = 5.331e-40 Identity = 109/354 (30.79%), Postives = 179/354 (50.56%), Query Frame = 1
Query: 115 PHINGYTHWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEG--VPEISLYKIAMPQHLTPT--EYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
PH THW VT+ G I+ S +L+ P +LV L++QE + +++ +E L ++ N++ + + + + C+KA L + L+ +SLE+K I DY A L + L QP C FS+ F HL I+ R L +P+ ++ + L T E GH + L + ++ +W+LYNMA+FYWR+K +EC ALH S + +DIALV++ANI H ++ DA +L+ A+ +S F + H LGNIYA LG++N+S+ Y A + IK R + C L +++Q + + + L+EL+ +Q + + Y
Sbjct: 62 PHSQATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVGYLKELEKHLVAQKIHIEENEDRDTGLEQRHYKDDPDCIKAKVPLGDLDLYDGTFISLESKNISPEDY---ADLHSALPPDLMQPDCTKIIELPFSIHAFHHLRGIQERLNLSAPLLPKEDPIFSSLHRRLGRTIDEMGHRIHEGLLK----NTTSWVLYNMASFYWRIKNEPYQVVECAMRALHFSSRQNKDIALVNMANILHRAHFSA-DAAILVHAALDVSSDFLTSHYTLGNIYAMLGEYNHSVLCYDRALQVKPGFDHAIK------RKHAVLCQQRLEQKLEAQHRSLQRTLNELKEYQKQHDHY 401 HSP 2 Score: 83.9593 bits (206), Expect = 1.246e-15 Identity = 48/163 (29.45%), Postives = 86/163 (52.76%), Query Frame = 1
Query: 3106 NLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
+LH +T D+ +G R++ G+ +N T W + ++ YWR+ + Q C A+ S ++ + LVN ANIL+R + A + H +L S +++ + + NI+A + ++N + L Y+ L +K F+ A+ R ++ CQQ + Q LE QH
Sbjct: 227 SLHRRLGRTIDE------MGHRIHEGLLKNTTSWVLYNMASFYWRIKNEPYQVVECAMRALHFSSRQNKDIALVNMANILHRAHFSADAAILVHAALDV--SSDFLTSHYTLGNIYAMLGEYNHSVLCYDRALQVKPGFDHAIKRKHAVLCQQRLEQKLEAQH 381 HSP 3 Score: 74.7146 bits (182), Expect = 7.868e-13 Identity = 37/81 (45.68%), Postives = 50/81 (61.73%), Query Frame = 1
Query: 1891 WILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
W + N A LYWR VGN QAL C R ++ LSP + + +PLVNLA +L+ + + DA KL+ A I+ SEP T + N Y
Sbjct: 646 WSVLNEAALYWRAVGNSTQALACLRRALNLSPPQQQHIPLVNLANLLMHYNLHSDASKLLLQALAIESSEPLTLLSLGNAY 726 HSP 4 Score: 68.5514 bits (166), Expect = 6.196e-11 Identity = 46/156 (29.49%), Postives = 78/156 (50.00%), Query Frame = 1
Query: 343 SESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNF--SMCCFEHLETIRNRSMLEGVPEISLYKIA--MPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPW 798
S C+K ++ E + ++ L++ AK I ++++ A ALQ+P E N N SM +HL + NR+ + E L ++ + + P + V + + + + +W+L +MAA YWRVKG + AI CLR ALH +P+
Sbjct: 975 SPEECLKHRRV--ELSTVASTWLAVSAKNIDITEHVDFA-------TALQEPGVEPLCNGNMAASMHTLDHLYGVANRAAIHYTGESQLKEVLQNLGKDKFPPQSLEQVGTRIMKVLEKNQTSWVLSSMAALYWRVKGQGQKAINCLRQALHHAPY 1121 HSP 5 Score: 60.8474 bits (146), Expect = 1.392e-8 Identity = 42/131 (32.06%), Postives = 63/131 (48.09%), Query Frame = 1
Query: 610 IAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL 1002
I++ + T H +A+ +G W + N AA YWR G++ A+ CLR AL+ SP + Q I LV+LAN+ S DA L+ A+ I + LGN Y SL +L ++ A +
Sbjct: 623 ISVSEEETAASLSHFIANPVG-------PIWSVLNEAALYWRAVGNSTQALACLRRALNLSPPQQQHIPLVNLANLLMHYNLHS-DASKLLLQALAIESSEPLTLLSLGNAYLSLKNLTGALQVFRAALDM 745 HSP 6 Score: 58.151 bits (139), Expect = 1.019e-7 Identity = 25/60 (41.67%), Postives = 40/60 (66.67%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILV 3327
SLE +G R+ +E+N T W +++++ YWRV G Q+A NCL A+ ++P +H KV L+
Sbjct: 1070 SLEQVGTRIMKVLEKNQTSWVLSSMAALYWRVKGQGQKAINCLRQALHHAP-YHMKVSLM 1128 HSP 7 Score: 58.151 bits (139), Expect = 1.099e-7 Identity = 30/100 (30.00%), Postives = 52/100 (52.00%), Query Frame = 1
Query: 1834 LEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
++++G RI + + S W+L+N+A YWRI Q ++C ++ S + +D+ LVN+A IL R + DA L+ A + +H N+Y
Sbjct: 236 IDEMGHRIHEGLLKNTTS-WVLYNMASFYWRIKNEPYQVVECAMRALHFSSRQNKDIALVNMANILHRAHFSADAAILVHAALDVSSDFLTSHYTLGNIY 334
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Mouse
Match: Ttc17 (tetratricopeptide repeat domain 17 [Source:MGI Symbol;Acc:MGI:1921819]) HSP 1 Score: 138.272 bits (347), Expect = 1.558e-32 Identity = 100/348 (28.74%), Postives = 181/348 (52.01%), Query Frame = 1
Query: 133 THWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEG--VPEISLYKIAMPQHLTPT--EYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
THW VT+ G I+ S +L+ P +LV L++QE + +++ +E +L ++ N++ + + + + C+KA L + L+ ++LE+K I+ D+++ + + + +QP C +S+ F+HL ++ R L +P+ + + L + + GHL+ L ++ +W+LYN+A+FYWR+K +EC ALH S +DIALV+LAN+ H S DA V++ A+ S FTS++ LGNIYA LG++N+S+ Y A + IK R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 40 THWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDIRPEDFIDTE--SPVPPDP-EQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGL----QKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAH-FSADAAVVVHAALDDSDFFTSYY-TLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIK------RKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHY 372 HSP 2 Score: 88.1965 bits (217), Expect = 5.087e-17 Identity = 44/123 (35.77%), Postives = 72/123 (58.54%), Query Frame = 1
Query: 1765 RSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
++ + H + LL ++ + E+IG + AI + W++ N AGLYWR VGN A+ C + ++ L+P++Y+D+PLVNLA +LI + + DA KL+ A ++ SEP T + N Y
Sbjct: 577 KAKIPDDHARKILLSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAY 699 HSP 3 Score: 82.0333 bits (201), Expect = 3.435e-15 Identity = 61/241 (25.31%), Postives = 115/241 (47.72%), Query Frame = 1
Query: 2896 DFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTP--------KGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
D Y Y++L + I +D+ +P + + P CT LR + ++ + +P+ + ++L R S++DIG ++ G+++NA+ W + ++ YWR+ + Q C A+ S ++ + LVN AN+L+R + A + H +L D ++ + + NI+A + ++N + L Y+ L K FE+A+ R ++ CQQ + Q LE QH
Sbjct: 123 DLDLYDGTYITLESKDIRPEDFIDTESP--VPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPL-----LPKEDPIFTYLSKRLGR-SIDDIGHLIHEGLQKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAAL---DDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQH 352 HSP 4 Score: 67.0106 bits (162), Expect = 1.448e-10 Identity = 36/101 (35.64%), Postives = 57/101 (56.44%), Query Frame = 1
Query: 700 WILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL 1002
W++ N A YWR G++ AI CL+ AL+ +P +YQDI LV+LAN+ + LDA L+ A+ ++ + LGN Y +L + +L ++ A L
Sbjct: 619 WLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLL-IHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKL 718
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Mouse
Match: Ttc17 (tetratricopeptide repeat domain 17 [Source:MGI Symbol;Acc:MGI:1921819]) HSP 1 Score: 137.117 bits (344), Expect = 4.243e-32 Identity = 100/348 (28.74%), Postives = 181/348 (52.01%), Query Frame = 1
Query: 133 THWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEG--VPEISLYKIAMPQHLTPT--EYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
THW VT+ G I+ S +L+ P +LV L++QE + +++ +E +L ++ N++ + + + + C+KA L + L+ ++LE+K I+ D+++ + + + +QP C +S+ F+HL ++ R L +P+ + + L + + GHL+ L ++ +W+LYN+A+FYWR+K +EC ALH S +DIALV+LAN+ H S DA V++ A+ S FTS++ LGNIYA LG++N+S+ Y A + IK R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 40 THWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDIRPEDFIDTE--SPVPPDP-EQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGL----QKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAH-FSADAAVVVHAALDDSDFFTSYY-TLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIK------RKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHY 372 HSP 2 Score: 122.094 bits (305), Expect = 2.040e-27 Identity = 83/287 (28.92%), Postives = 142/287 (49.48%), Query Frame = 1
Query: 190 HLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNF--SMCCFEHLETIRNRSMLEGVPEISLYKIA--MPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
H + P V+ Q E + +E+ +V++ QE + S C+K + E T + L++ +K I ++++ A +QQP E N N SM +HL + NR+ L E L ++ + + P + + + + + + +W+L +MAA YWRVKG K AI+CLR ALH +P + +D+ L+SLANI H K + DA+++ A+ I+PHF +H LGN+Y ++ +F +L Y+ L + P K++I+
Sbjct: 852 HKKPPGKKVEASQAENGQRYQANLEITGPKVASP--GPQEKKRDYQSLGWPSPDECLKLRWV--ELTAIVSTWLAVSSKNIDITEHIDFA-------TPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWN-DAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQ 1126 HSP 3 Score: 90.8929 bits (224), Expect = 7.574e-18 Identity = 46/144 (31.94%), Postives = 85/144 (59.03%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQN 3579
SLE IG R+ +E+N T W +++++ YWRV G ++A +CL A+ +P + V L++ ANIL+ A+ + +++ + ++ V F + N++ ME++ KA ++YE+ L L+ +F A RI++IQC M+ +
Sbjct: 996 SLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEI--APHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKG 1137 HSP 4 Score: 88.1965 bits (217), Expect = 5.524e-17 Identity = 44/123 (35.77%), Postives = 72/123 (58.54%), Query Frame = 1
Query: 1765 RSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
++ + H + LL ++ + E+IG + AI + W++ N AGLYWR VGN A+ C + ++ L+P++Y+D+PLVNLA +LI + + DA KL+ A ++ SEP T + N Y
Sbjct: 577 KAKIPDDHARKILLSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAY 699 HSP 5 Score: 81.2629 bits (199), Expect = 6.679e-15 Identity = 61/241 (25.31%), Postives = 115/241 (47.72%), Query Frame = 1
Query: 2896 DFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTP--------KGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
D Y Y++L + I +D+ +P + + P CT LR + ++ + +P+ + ++L R S++DIG ++ G+++NA+ W + ++ YWR+ + Q C A+ S ++ + LVN AN+L+R + A + H +L D ++ + + NI+A + ++N + L Y+ L K FE+A+ R ++ CQQ + Q LE QH
Sbjct: 123 DLDLYDGTYITLESKDIRPEDFIDTESP--VPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPL-----LPKEDPIFTYLSKRLGR-SIDDIGHLIHEGLQKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAAL---DDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQH 352 HSP 6 Score: 68.5514 bits (166), Expect = 4.998e-11 Identity = 52/172 (30.23%), Postives = 82/172 (47.67%), Query Frame = 1
Query: 1618 LTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
+T H + + P P N T + +D L + N S G S E +LQ L K Q LE IG RI +++ ++W+L ++A LYWR+ G +A+DC R ++ +P + +DVPL++LA IL + DA+ + A +I H N+Y
Sbjct: 930 ITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVS--NRASLHYTGESQLTE--VLQNLGK-DQYPQQSLEQIGTRIAKVLEKN-QTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVY 1095 HSP 7 Score: 66.6254 bits (161), Expect = 2.202e-10 Identity = 36/101 (35.64%), Postives = 57/101 (56.44%), Query Frame = 1
Query: 700 WILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL 1002
W++ N A YWR G++ AI CL+ AL+ +P +YQDI LV+LAN+ + LDA L+ A+ ++ + LGN Y +L + +L ++ A L
Sbjct: 619 WLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLL-IHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKL 718
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Mouse
Match: Ttc17 (tetratricopeptide repeat domain 17 [Source:MGI Symbol;Acc:MGI:1921819]) HSP 1 Score: 137.117 bits (344), Expect = 4.625e-32 Identity = 100/348 (28.74%), Postives = 181/348 (52.01%), Query Frame = 1
Query: 133 THWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEG--VPEISLYKIAMPQHLTPT--EYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
THW VT+ G I+ S +L+ P +LV L++QE + +++ +E +L ++ N++ + + + + C+KA L + L+ ++LE+K I+ D+++ + + + +QP C +S+ F+HL ++ R L +P+ + + L + + GHL+ L ++ +W+LYN+A+FYWR+K +EC ALH S +DIALV+LAN+ H S DA V++ A+ S FTS++ LGNIYA LG++N+S+ Y A + IK R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 40 THWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDIRPEDFIDTE--SPVPPDP-EQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGL----QKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAH-FSADAAVVVHAALDDSDFFTSYY-TLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIK------RKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHY 372 HSP 2 Score: 121.709 bits (304), Expect = 2.791e-27 Identity = 83/287 (28.92%), Postives = 142/287 (49.48%), Query Frame = 1
Query: 190 HLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNF--SMCCFEHLETIRNRSMLEGVPEISLYKIA--MPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
H + P V+ Q E + +E+ +V++ QE + S C+K + E T + L++ +K I ++++ A +QQP E N N SM +HL + NR+ L E L ++ + + P + + + + + + +W+L +MAA YWRVKG K AI+CLR ALH +P + +D+ L+SLANI H K + DA+++ A+ I+PHF +H LGN+Y ++ +F +L Y+ L + P K++I+
Sbjct: 909 HKKPPGKKVEASQAENGQRYQANLEITGPKVASP--GPQEKKRDYQSLGWPSPDECLKLRWV--ELTAIVSTWLAVSSKNIDITEHIDFA-------TPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWN-DAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQ 1183 HSP 3 Score: 90.8929 bits (224), Expect = 8.235e-18 Identity = 46/144 (31.94%), Postives = 85/144 (59.03%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQN 3579
SLE IG R+ +E+N T W +++++ YWRV G ++A +CL A+ +P + V L++ ANIL+ A+ + +++ + ++ V F + N++ ME++ KA ++YE+ L L+ +F A RI++IQC M+ +
Sbjct: 1053 SLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEI--APHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKG 1194 HSP 4 Score: 87.8113 bits (216), Expect = 5.998e-17 Identity = 44/123 (35.77%), Postives = 72/123 (58.54%), Query Frame = 1
Query: 1765 RSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
++ + H + LL ++ + E+IG + AI + W++ N AGLYWR VGN A+ C + ++ L+P++Y+D+PLVNLA +LI + + DA KL+ A ++ SEP T + N Y
Sbjct: 577 KAKIPDDHARKILLSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAY 699 HSP 5 Score: 81.6481 bits (200), Expect = 5.901e-15 Identity = 61/241 (25.31%), Postives = 115/241 (47.72%), Query Frame = 1
Query: 2896 DFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTP--------KGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
D Y Y++L + I +D+ +P + + P CT LR + ++ + +P+ + ++L R S++DIG ++ G+++NA+ W + ++ YWR+ + Q C A+ S ++ + LVN AN+L+R + A + H +L D ++ + + NI+A + ++N + L Y+ L K FE+A+ R ++ CQQ + Q LE QH
Sbjct: 123 DLDLYDGTYITLESKDIRPEDFIDTESP--VPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPL-----LPKEDPIFTYLSKRLGR-SIDDIGHLIHEGLQKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAAL---DDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQH 352 HSP 6 Score: 68.5514 bits (166), Expect = 5.341e-11 Identity = 52/172 (30.23%), Postives = 82/172 (47.67%), Query Frame = 1
Query: 1618 LTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
+T H + + P P N T + +D L + N S G S E +LQ L K Q LE IG RI +++ ++W+L ++A LYWR+ G +A+DC R ++ +P + +DVPL++LA IL + DA+ + A +I H N+Y
Sbjct: 987 ITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVS--NRASLHYTGESQLTE--VLQNLGK-DQYPQQSLEQIGTRIAKVLEKN-QTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVY 1152 HSP 7 Score: 66.6254 bits (161), Expect = 2.312e-10 Identity = 36/101 (35.64%), Postives = 57/101 (56.44%), Query Frame = 1
Query: 700 WILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL 1002
W++ N A YWR G++ AI CL+ AL+ +P +YQDI LV+LAN+ + LDA L+ A+ ++ + LGN Y +L + +L ++ A L
Sbjct: 619 WLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLL-IHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKL 718
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Mouse
Match: Ttc17 (tetratricopeptide repeat domain 17 [Source:MGI Symbol;Acc:MGI:1921819]) HSP 1 Score: 122.094 bits (305), Expect = 7.034e-28 Identity = 85/289 (29.41%), Postives = 143/289 (49.48%), Query Frame = 1
Query: 190 HLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNF--SMCCFEHLETIRNRSMLEGVPEISLYKIAMPQHLTPTEYGHL----VASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
H + P V+ Q E + +E+ +V++ QE + S C+K + E T + L++ +K I ++++ A +QQP E N N SM +HL + NR+ L E L ++ Q+L +Y + + + + + +W+L +MAA YWRVKG K AI+CLR ALH +P + +D+ L+SLANI H K + DA+++ A+ I+PHF +H LGN+Y ++ +F +L Y+ L + P K++I+
Sbjct: 336 HKKPPGKKVEASQAENGQRYQANLEITGPKVASP--GPQEKKRDYQSLGWPSPDECLKLRWV--ELTAIVSTWLAVSSKNIDITEHIDFA-------TPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVL--QNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWN-DAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQ 610 HSP 2 Score: 90.1225 bits (222), Expect = 7.381e-18 Identity = 48/150 (32.00%), Postives = 88/150 (58.67%), Query Frame = 1
Query: 3139 DRY---SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQN 3579
D+Y SLE IG R+ +E+N T W +++++ YWRV G ++A +CL A+ +P + V L++ ANIL+ A+ + +++ + ++ V F + N++ ME++ KA ++YE+ L L+ +F A RI++IQC M+ +
Sbjct: 474 DQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEI--APHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKG 621 HSP 3 Score: 87.8113 bits (216), Expect = 3.686e-17 Identity = 44/123 (35.77%), Postives = 72/123 (58.54%), Query Frame = 1
Query: 1765 RSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
++ + H + LL ++ + E+IG + AI + W++ N AGLYWR VGN A+ C + ++ L+P++Y+D+PLVNLA +LI + + DA KL+ A ++ SEP T + N Y
Sbjct: 4 KAKIPDDHARKILLSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAY 126 HSP 4 Score: 68.1662 bits (165), Expect = 4.437e-11 Identity = 52/172 (30.23%), Postives = 82/172 (47.67%), Query Frame = 1
Query: 1618 LTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
+T H + + P P N T + +D L + N S G S E +LQ L K Q LE IG RI +++ ++W+L ++A LYWR+ G +A+DC R ++ +P + +DVPL++LA IL + DA+ + A +I H N+Y
Sbjct: 414 ITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGV--SNRASLHYTGESQLTE--VLQNLGK-DQYPQQSLEQIGTRIAKVLEKN-QTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVY 579 HSP 5 Score: 66.2402 bits (160), Expect = 2.023e-10 Identity = 36/101 (35.64%), Postives = 57/101 (56.44%), Query Frame = 1
Query: 700 WILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL 1002
W++ N A YWR G++ AI CL+ AL+ +P +YQDI LV+LAN+ + LDA L+ A+ ++ + LGN Y +L + +L ++ A L
Sbjct: 46 WLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLL-IHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKL 145
BLAST of Tetratricopeptide repeat domain 17 vs. UniProt/SwissProt
Match: sp|E7F211|TTC17_DANRE (Tetratricopeptide repeat protein 17 OS=Danio rerio OX=7955 GN=ttc17 PE=3 SV=1) HSP 1 Score: 145.976 bits (367), Expect = 6.835e-34 Identity = 96/349 (27.51%), Postives = 184/349 (52.72%), Query Frame = 1
Query: 133 THWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEIS-----LYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
THW VT+ G I+ S +L+ P +LV +QQE + +++++E +L ++ N++ + + + ++ CV A L + L+ +SLE+K I +L+ L + L++P C + +S+ F+HL ++ + L P +S + + + E GH + +L + +S +W+LYN+A+FYWR+K + A++C+ ALH SP +++D+ALV++AN+ H ++ AI+ L + TSH+ LGNIYA LG++N+S+ Y+ A + ++ R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 57 THWVVTEDGKIQQQVDSPLNLKHPHHLVLFMQQETRVNYLKKLEKQLVAQKIHIEENEDRDTGLEQRHYKEDADCVTAKVPLGDLDLYDGTFISLESKDINPEQFLD---LMSALPPDLEKPDCAKLLDLPYSIHAFQHLRGVQEKVNLTS-PLLSKDDPIFTSLCLKLGQSVDEVGHRIHQALLK----NSSSWVLYNLASFYWRIKNEPRRAVDCVVRALHFSPRQHKDVALVNMANVLHRAHFSADAAILAHAALDLTTDLLTSHY-TLGNIYAMLGEYNHSVLCYEQALQAQPGFEQALR------RKHAVLCQQKLEQRLEAQHRSLQRTLNELKEYQKQHDHY 390 HSP 2 Score: 117.472 bits (293), Expect = 3.383e-25 Identity = 67/214 (31.31%), Postives = 114/214 (53.27%), Query Frame = 1
Query: 409 LSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNF--SMCCFEHLETIRNRSMLEGVPEISLYKIA--MPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
L++ AK I ++++ A LQ+P E N N SM +HL + NR + E L ++ + + P++ V + + + + +W+L +MAA YWRVKG K AI+CLR AL+ +P +D+ L+SLANIF + DA+ + + A+ I+PHF +H L N+Y ++ +F ++H Y+ L + P KD+++
Sbjct: 978 LAVSAKNIDITEHIDFA-------TPLQEPAVEPVCNANLPASMHTLDHLSGVANRGGIHYTGESQLREVLQNLGKDKFPSQSFEQVGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKRAIDCLRQALNYAPHHMKDVPLISLANIFQNARLWE-DALTVARMAVEIAPHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFGPAKDRLR 1183 HSP 3 Score: 96.6709 bits (239), Expect = 1.030e-18 Identity = 63/241 (26.14%), Postives = 117/241 (48.55%), Query Frame = 1
Query: 2863 APEDCEHVAPFDFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCT---PKGT---NFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRY---SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQC 3558
PE+C+ D T +++++ I++ +D TP L P C P + L + ++ I Y+ E L D++ S E +G R+ +E+N T W +++++ YWRV G ++A +CL A+ +P + V L++ ANI E AL + +++ + +++V F +AN++ ME++ KA +YE+ L L+ +F A R+++IQC
Sbjct: 958 GPEECQRTRRVDLTTVASTWLAVSAKNIDITEHIDFATP--LQEPAVEPVCNANLPASMHTLDHLSGVANRGGI-----HYTG--ESQLREVLQNLGKDKFPSQSFEQVGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKRAIDCLRQALNYAPHHMKDVPLISLANIFQNARLWEDALTVARMAVEI--APHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFGPAKDRLRTIQC 1187 HSP 4 Score: 80.8777 bits (198), Expect = 5.601e-14 Identity = 43/149 (28.86%), Postives = 84/149 (56.38%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
S++++G R++ + +N++ W + ++ YWR+ + ++A +C+ A+ SP H+ V LVN AN+L+R + +A + + + + + NI+A + ++N + L YE L + FE+A+ R ++ CQQ + Q LE QH
Sbjct: 224 SVDEVGHRIHQALLKNSSSWVLYNLASFYWRIKNEPRRAVDCVVRALHFSPRQHKDVALVNMANVLHRAHF--SADAAILAHAALDLTTDLLTSHYTLGNIYAMLGEYNHSVLCYEQALQAQPGFEQALRRKHAVLCQQKLEQRLEAQH 370 HSP 5 Score: 78.5666 bits (192), Expect = 3.027e-13 Identity = 43/120 (35.83%), Postives = 69/120 (57.50%), Query Frame = 1
Query: 1801 LLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLA 2160
LLK G + LE G I A+++ W++ N AGL+WR GN QAL C R ++ +P ++RD+PLVN A +L+ + + +A +L++ A +I+ SEP T + N++ L A
Sbjct: 602 LLKRSGGRS--LEQTGALIAQALEKMSGPRWMMQNEAGLFWRAKGNGTQALVCLRQALHSAPPQHRDLPLVNTANLLLHYGLHSEAHELLQQALQINQSEPHTLLSLVNVHLSQGNLTGA 719 HSP 6 Score: 71.2478 bits (173), Expect = 4.891e-11 Identity = 47/173 (27.17%), Postives = 84/173 (48.55%), Query Frame = 1
Query: 1735 DNLISYQNKGRSNFAEKHLLQELLKLV---QGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKL 2244
D+L N+G ++ + L+E+L+ + + + E +G RI +++ ++W+L ++A LYWR+ G +A+DC R ++ +P +DVPL++LA I + +DA+ + A +I H AN+Y E A H E + L I+C L
Sbjct: 1018 DHLSGVANRGGIHYTGESQLREVLQNLGKDKFPSQSFEQVGTRIAKVLEKN-QTSWVLSSMAALYWRVKGQGKRAIDCLRQALNYAPHHMKDVPLISLANIFQNARLWEDALTVARMAVEIAPHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFGPAKDRLRTIQCYL 1189 HSP 7 Score: 63.1586 bits (152), Expect = 1.438e-8 Identity = 38/117 (32.48%), Postives = 64/117 (54.70%), Query Frame = 1
Query: 646 GHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILIS---PH----FTSHHMILGNIYASLGQFNNSL 975
G L+A +L + S W++ N A +WR KG+ A+ CLR ALH++P +++D+ LV+ AN+ L +A L++ A+ I+ PH + H+ GN+ +L F +L
Sbjct: 615 GALIAQALEKM---SGPRWMMQNEAGLFWRAKGNGTQALVCLRQALHSAPPQHRDLPLVNTANLL-LHYGLHSEAHELLQQALQINQSEPHTLLSLVNVHLSQGNLTGALAVFRQAL 727 HSP 8 Score: 59.3066 bits (142), Expect = 2.645e-7 Identity = 31/78 (39.74%), Postives = 49/78 (62.82%), Query Frame = 1
Query: 1804 LKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIR 2037
LKL Q V+ ++G RI A+ + S+W+L+N+A YWRI +A+DC ++ SP +++DV LVN+A +L R
Sbjct: 219 LKLGQSVD----EVGHRIHQALLKN-SSSWVLYNLASFYWRIKNEPRRAVDCVVRALHFSPRQHKDVALVNMANVLHR 291
BLAST of Tetratricopeptide repeat domain 17 vs. UniProt/SwissProt
Match: sp|Q96AE7|TTC17_HUMAN (Tetratricopeptide repeat protein 17 OS=Homo sapiens OX=9606 GN=TTC17 PE=1 SV=1) HSP 1 Score: 139.043 bits (349), Expect = 9.045e-32 Identity = 102/348 (29.31%), Postives = 180/348 (51.72%), Query Frame = 1
Query: 133 THWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEG--VPEISLYKIAMPQHLTPT--EYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
THW VT+ G I+ S +L+ P +LV L++QE + +++ +E +L ++ N++ + + + + C+KA L + L+ ++LE+K I DY++ + + + +QP C +S+ F+HL ++ R L +P+ + + L + + GHL+ L ++ +W+LYNMA+FYWR+K +EC ALH S +DIALV+LAN+ H S DA V++ A+ S FTS++ LGNIYA LG++N+S+ Y A + IK R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 40 THWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQEATVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDISPEDYIDTE--SPVPPDP-EQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGL----QKNTSSWVLYNMASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAH-FSADAAVVVHAALDDSDFFTSYY-TLGNIYAMLGEYNHSVLCYDHALQARPGFEQAIK------RKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHY 372 HSP 2 Score: 119.013 bits (297), Expect = 1.309e-25 Identity = 82/287 (28.57%), Postives = 142/287 (49.48%), Query Frame = 1
Query: 190 HLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNF--SMCCFEHLETIRNRSMLEGVPEISLYKIA--MPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
H + P V+ Q E + +E+ +V++ Q + + S C+K + E T + L++ +K I ++++ A +QQP E N N SM +HL + NR+ L E L ++ + + P + + + + + + +W+L +MAA YWRVKG K AI+CLR ALH +P + +D+ L+SLANI H K + DA+++ A+ I+PHF +H LGN+Y ++ +F +L Y+ L + P K++I+
Sbjct: 852 HKKTPGKKVETGQIENGHRYQANLEITGPKVASP--GPQGKKRDYQRLGWPSPDECLKLRWV--ELTAIVSTWLAVSSKNIDITEHIDFA-------TPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWN-DAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQ 1126 HSP 3 Score: 90.8929 bits (224), Expect = 5.767e-17 Identity = 46/144 (31.94%), Postives = 85/144 (59.03%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQN 3579
SLE IG R+ +E+N T W +++++ YWRV G ++A +CL A+ +P + V L++ ANIL+ A+ + +++ + ++ V F + N++ ME++ KA ++YE+ L L+ +F A RI++IQC M+ +
Sbjct: 996 SLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEI--APHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKG 1137 HSP 4 Score: 88.1965 bits (217), Expect = 3.288e-16 Identity = 46/123 (37.40%), Postives = 71/123 (57.72%), Query Frame = 1
Query: 1765 RSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
++ + H + LL + + E+IG + AI + W++ N AGLYWR VGN A+ C + ++ L+P++Y+DVPLVNLA +LI + + DA KL+ A I+ SEP T + N Y
Sbjct: 577 KAKMPDDHARKILLSRINNYTIPEEEIGSFLFHAINKPNAPIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVNLANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAY 699 HSP 5 Score: 78.5666 bits (192), Expect = 3.579e-13 Identity = 44/149 (29.53%), Postives = 82/149 (55.03%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
S++DIG ++ G+++N + W + ++ YWR+ + Q C A+ S ++ + LVN AN+L+R + A + H +L D ++ + + NI+A + ++N + L Y+ L + FE+A+ R ++ CQQ + Q LE QH
Sbjct: 207 SIDDIGHLIHEGLQKNTSSWVLYNMASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAAL---DDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQARPGFEQAIKRKHAVLCQQKLEQKLEAQH 352 HSP 6 Score: 68.5514 bits (166), Expect = 3.380e-10 Identity = 52/172 (30.23%), Postives = 82/172 (47.67%), Query Frame = 1
Query: 1618 LTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
+T H + + P P N T + +D L + N S G S E +LQ L K Q LE IG RI +++ ++W+L ++A LYWR+ G +A+DC R ++ +P + +DVPL++LA IL + DA+ + A +I H N+Y
Sbjct: 930 ITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVS--NRASLHYTGESQLTE--VLQNLGK-DQYPQQSLEQIGTRIAKVLEKN-QTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVY 1095 HSP 7 Score: 66.2402 bits (160), Expect = 1.720e-9 Identity = 36/101 (35.64%), Postives = 57/101 (56.44%), Query Frame = 1
Query: 700 WILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL 1002
W++ N A YWR G++ AI CL+ AL+ +P +YQD+ LV+LAN+ + LDA L+ A+ I+ + LGN Y +L + +L ++ A L
Sbjct: 619 WLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVNLANLL-IHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKL 718
BLAST of Tetratricopeptide repeat domain 17 vs. UniProt/SwissProt
Match: sp|B5DEL3|TTC17_RAT (Tetratricopeptide repeat protein 17 OS=Rattus norvegicus OX=10116 GN=Ttc17 PE=1 SV=1) HSP 1 Score: 137.887 bits (346), Expect = 1.780e-31 Identity = 100/348 (28.74%), Postives = 181/348 (52.01%), Query Frame = 1
Query: 133 THWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEG--VPEISLYKIAMPQHLTPT--EYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
THW VT+ G I+ S +L+ P +LV L++QE + +++ +E +L ++ N++ + + + + C+KA L + L+ ++LE+K ++ D+++ + + + +QP C +S+ F+HL ++ R L +P+ + + L + + GHL+ L +S +W+LYN+A+FYWR+K +EC ALH S +DIALV+LAN+ H S DA V++ A+ S FTS++ LGNIYA LG++N+S+ Y A + IK R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 40 THWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDVRPEDFIDTE--SPVPPDP-EQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGL----QKNSSSWVLYNLASFYWRIKNEPYQVVECTMRALHFSSRHNKDIALVNLANVLHRAH-FSADAAVVVHAALDDSAFFTSYY-TLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIK------RKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHY 372 HSP 2 Score: 122.865 bits (307), Expect = 9.227e-27 Identity = 84/287 (29.27%), Postives = 142/287 (49.48%), Query Frame = 1
Query: 190 HLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNF--SMCCFEHLETIRNRSMLEGVPEISLYKIA--MPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
H + P V+ Q E + +E+ +V++ QE + S C+K + E T + L++ +K I ++++ A +QQP E N N SM +HL + NR+ L E L ++ + + P + + + + + + +W+L +MAA YWRVKG K AI+CLR ALH +P + +D+ L+SLANI H K + DA+V+ A+ I+PHF +H LGN+Y ++ +F +L Y+ L + P K++I+
Sbjct: 909 HKKPPGKKVEASQAENGQRYQANLEITGPKVASP--GPQEKKRDYQSMGWPSPDECLKLRWV--ELTAIVSTWLAVSSKNIDITEHIDFA-------TPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWN-DAVVVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQ 1183 HSP 3 Score: 91.2781 bits (225), Expect = 3.898e-17 Identity = 46/144 (31.94%), Postives = 85/144 (59.03%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQN 3579
SLE IG R+ +E+N T W +++++ YWRV G ++A +CL A+ +P + V L++ ANIL+ A+ + +++ + ++ V F + N++ ME++ KA ++YE+ L L+ +F A RI++IQC M+ +
Sbjct: 1053 SLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVVVATMAVEI--APHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKG 1194 HSP 4 Score: 88.5817 bits (218), Expect = 2.745e-16 Identity = 44/123 (35.77%), Postives = 72/123 (58.54%), Query Frame = 1
Query: 1765 RSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
++ + H + LL ++ + E+IG + AI + W++ N AGLYWR VGN A+ C + ++ L+P++Y+D+PLVNLA +LI + + DA KL+ A ++ SEP T + N Y
Sbjct: 577 KAKIPDDHARKILLSRIKNYTIPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQALAVNSSEPLTFLSLGNAY 699 HSP 5 Score: 78.9518 bits (193), Expect = 2.512e-13 Identity = 45/149 (30.20%), Postives = 82/149 (55.03%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
S++DIG ++ G+++N++ W + ++ YWR+ + Q C A+ S ++ + LVN AN+L+R + A + H +L D + + + NI+A + ++N + L Y+ L K FE+A+ R ++ CQQ + Q LE QH
Sbjct: 207 SIDDIGHLIHEGLQKNSSSWVLYNLASFYWRIKNEPYQVVECTMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAAL---DDSAFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQH 352 HSP 6 Score: 68.9366 bits (167), Expect = 2.731e-10 Identity = 52/172 (30.23%), Postives = 82/172 (47.67%), Query Frame = 1
Query: 1618 LTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
+T H + + P P N T + +D L + N S G S E +LQ L K Q LE IG RI +++ ++W+L ++A LYWR+ G +A+DC R ++ +P + +DVPL++LA IL + DA+ + A +I H N+Y
Sbjct: 987 ITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVS--NRASLHYTGESQLTE--VLQNLGK-DQYPQQSLEQIGTRIAKVLEKN-QTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVVVATMAVEIAPHFAVNHFTLGNVY 1152 HSP 7 Score: 66.2402 bits (160), Expect = 2.121e-9 Identity = 36/101 (35.64%), Postives = 57/101 (56.44%), Query Frame = 1
Query: 700 WILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL 1002
W++ N A YWR G++ AI CL+ AL+ +P +YQDI LV+LAN+ + LDA L+ A+ ++ + LGN Y +L + +L ++ A L
Sbjct: 619 WLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLL-IHYGLHLDATKLLLQALAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKL 718
BLAST of Tetratricopeptide repeat domain 17 vs. UniProt/SwissProt
Match: sp|E9PVB5|TTC17_MOUSE (Tetratricopeptide repeat protein 17 OS=Mus musculus OX=10090 GN=Ttc17 PE=1 SV=1) HSP 1 Score: 137.117 bits (344), Expect = 3.235e-31 Identity = 100/348 (28.74%), Postives = 181/348 (52.01%), Query Frame = 1
Query: 133 THWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEG--VPEISLYKIAMPQHLTPT--EYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
THW VT+ G I+ S +L+ P +LV L++QE + +++ +E +L ++ N++ + + + + C+KA L + L+ ++LE+K I+ D+++ + + + +QP C +S+ F+HL ++ R L +P+ + + L + + GHL+ L ++ +W+LYN+A+FYWR+K +EC ALH S +DIALV+LAN+ H S DA V++ A+ S FTS++ LGNIYA LG++N+S+ Y A + IK R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 40 THWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDIRPEDFIDTE--SPVPPDP-EQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGL----QKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAH-FSADAAVVVHAALDDSDFFTSYY-TLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIK------RKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHY 372 HSP 2 Score: 121.709 bits (304), Expect = 1.952e-26 Identity = 83/287 (28.92%), Postives = 142/287 (49.48%), Query Frame = 1
Query: 190 HLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNF--SMCCFEHLETIRNRSMLEGVPEISLYKIA--MPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
H + P V+ Q E + +E+ +V++ QE + S C+K + E T + L++ +K I ++++ A +QQP E N N SM +HL + NR+ L E L ++ + + P + + + + + + +W+L +MAA YWRVKG K AI+CLR ALH +P + +D+ L+SLANI H K + DA+++ A+ I+PHF +H LGN+Y ++ +F +L Y+ L + P K++I+
Sbjct: 909 HKKPPGKKVEASQAENGQRYQANLEITGPKVASP--GPQEKKRDYQSLGWPSPDECLKLRWV--ELTAIVSTWLAVSSKNIDITEHIDFA-------TPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWN-DAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQ 1183 HSP 3 Score: 90.8929 bits (224), Expect = 5.760e-17 Identity = 46/144 (31.94%), Postives = 85/144 (59.03%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQN 3579
SLE IG R+ +E+N T W +++++ YWRV G ++A +CL A+ +P + V L++ ANIL+ A+ + +++ + ++ V F + N++ ME++ KA ++YE+ L L+ +F A RI++IQC M+ +
Sbjct: 1053 SLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEI--APHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKG 1194 HSP 4 Score: 87.8113 bits (216), Expect = 4.196e-16 Identity = 44/123 (35.77%), Postives = 72/123 (58.54%), Query Frame = 1
Query: 1765 RSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
++ + H + LL ++ + E+IG + AI + W++ N AGLYWR VGN A+ C + ++ L+P++Y+D+PLVNLA +LI + + DA KL+ A ++ SEP T + N Y
Sbjct: 577 KAKIPDDHARKILLSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAY 699 HSP 5 Score: 81.6481 bits (200), Expect = 4.128e-14 Identity = 61/241 (25.31%), Postives = 115/241 (47.72%), Query Frame = 1
Query: 2896 DFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTP--------KGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
D Y Y++L + I +D+ +P + + P CT LR + ++ + +P+ + ++L R S++DIG ++ G+++NA+ W + ++ YWR+ + Q C A+ S ++ + LVN AN+L+R + A + H +L D ++ + + NI+A + ++N + L Y+ L K FE+A+ R ++ CQQ + Q LE QH
Sbjct: 123 DLDLYDGTYITLESKDIRPEDFIDTESP--VPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPL-----LPKEDPIFTYLSKRLGR-SIDDIGHLIHEGLQKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAAL---DDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQH 352 HSP 6 Score: 68.5514 bits (166), Expect = 3.736e-10 Identity = 52/172 (30.23%), Postives = 82/172 (47.67%), Query Frame = 1
Query: 1618 LTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
+T H + + P P N T + +D L + N S G S E +LQ L K Q LE IG RI +++ ++W+L ++A LYWR+ G +A+DC R ++ +P + +DVPL++LA IL + DA+ + A +I H N+Y
Sbjct: 987 ITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVS--NRASLHYTGESQLTE--VLQNLGK-DQYPQQSLEQIGTRIAKVLEKN-QTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVY 1152 HSP 7 Score: 66.6254 bits (161), Expect = 1.617e-9 Identity = 36/101 (35.64%), Postives = 57/101 (56.44%), Query Frame = 1
Query: 700 WILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL 1002
W++ N A YWR G++ AI CL+ AL+ +P +YQDI LV+LAN+ + LDA L+ A+ ++ + LGN Y +L + +L ++ A L
Sbjct: 619 WLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLL-IHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKL 718
BLAST of Tetratricopeptide repeat domain 17 vs. TrEMBL
Match: A0A0B7BGE5 (Uncharacterized protein OS=Arion vulgaris OX=1028688 GN=ORF181770 PE=4 SV=1) HSP 1 Score: 350.517 bits (898), Expect = 3.100e-100 Identity = 243/754 (32.23%), Postives = 397/754 (52.65%), Query Frame = 1
Query: 67 SYIYVILFLMGIIPPLPHINGYTHWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDY--LNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEISLYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRYQDIKISLIHEIENNATQERNQIIYKTLG-KLKPHQLVQ-CVISDLLTKEESVCELSTES-LITHIFKDLNRSPSESNRQEFQSDKELFRPTR---------SRVYKTLRLEQYK------------PSEYVHNINETSCKRLNCPRNYDXXXXXXXXXXXXKGFDLDNLLTTKQQLTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRS--NFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKL 2244
S I ++L I+ NG THW VT+ G I+ S Y+LR+P++LV ++QE + ++ +L +++ N++ + + + + C++A K L EF L+ + +L LE KGI+ ++ LN + TN + P C F + +FSM FEHLE ++ RS L G PE+ L K A+ +YGHLV +L N + +WILYNMAAFYWR+KG+ A+EC+R ALH SP +D+AL+SLANI H + ++ +A +L+ A+ +S +H LGNIYA LG++N S+ ++ N K + + +R + C +L +A+++Q + + + L +L+ +Q + + YQ L+ E + + + Y+ L + K ++ + C + D K+ +C S S + F L +P ++N + E F P + S+ KT +YK PS +I +T K++ RN L ++Y+SP +KGF++ LLT Q L EH LPWYPP C + + + P + D L+S +SY + R + + + + LL V + E++GQRI++A+K+ + WIL+N+AGLYWRI+GN ++C R ++ LSP++YRDVPLVNLA IL R+ R DA+ +++ A I+ +EP +H L +L A HH + + + + A+KC L
Sbjct: 3 STITMVLLASFILQRCTITNGSTHWMVTEDGRIQSQADSVYNLRRPYDLVAFMKQEDRASMLNILKKELLTRKDEIDKNEDRDTGLEQKFYRTNPDCIEAGKPLPEFDLYISTVLPLENKGIRAEEHIDLNGSPSTNP-----RSPDCTVFTDLDFSMHAFEHLEGMKARSNLSGSPELGL-KNAITHRENVDDYGHLVYEAL----NKNKTSWILYNMAAFYWRIKGNPYQAVECIRRALHHSPRLQKDVALISLANILHRARFSN-EAAILVHAALEVSKELNVNHFTLGNIYAVLGEYNKSIICFE------NTLKIQPDFEAASKRKHAVLCHSKLEMALEAQHRSLQRTLKDLKDYQRKHDLYQMQSDKLLAEQVPHEVKVAQHLAYEQLKMREKSAEMDEYCRMVDREGKQVLLCTWSRRSPTLDFDFAFLEEAPEKTNDENIS---EKFMPGQKTNSKSPNYSQPVKTPLYSKYKKHKNTEADPYMLPSWPTKDICDTYVKKVPDSRN----LTTVYLSPENKGFEVKELLTEAQGLEQEGEHPLPWYPPVCVPLMELAEGNPT-VYDHLKS------VSYAERSRIPLKYNDPSMRKILLDHVNNGFVTEEEVGQRILSALKQNIGPQWILYNLAGLYWRIIGNNYHGIECIRRAIYLSPVQYRDVPLVNLANILYRYGRYDDAIIIMKDALDINDAEPASHFLLGHLLWATRNYTGAAHHYQEVLAADENYPGALDTIRAMKCYL 725 HSP 2 Score: 88.1965 bits (217), Expect = 1.041e-13 Identity = 52/172 (30.23%), Postives = 87/172 (50.58%), Query Frame = 1
Query: 3079 SQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
S S PE L + R +++D G +Y + +N T W + ++ YWR+ G+ QA C+ A+ +SP + V L++ ANIL+R A + H +L+ N V F + NI+A + ++NK+ + +E L ++ DFE A R ++ C + LE QH
Sbjct: 168 SNLSGSPELGLKNAITH----RENVDDYGHLVYEALNKNKTSWILYNMAAFYWRIKGNPYQAVECIRRALHHSPRLQKDVALISLANILHRARFSNEAAILVHAALEVSKELN--VNHFTLGNIYAVLGEYNKSIICFENTLKIQPDFEAASKRKHAVLCHSKLEMALEAQH 333 HSP 3 Score: 65.4698 bits (158), Expect = 8.937e-7 Identity = 36/136 (26.47%), Postives = 70/136 (51.47%), Query Frame = 1
Query: 3154 EDIGKRLYTGIEQN-ATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQC 3558
E++G+R+ + ++QN W + ++ YWR+ G+ C+ A+ SP + V LVN ANILYR + + A+ I +L D++ FL+ ++ + A Y+ L+ ++ A+ I++++C
Sbjct: 590 EEVGQRILSALKQNIGPQWILYNLAGLYWRIIGNNYHGIECIRRAIYLSPVQYRDVPLVNLANILYRYGRYDDAIIIMKDALDINDAEP--ASHFLLGHLLWATRNYTGAAHHYQEVLAADENYPGALDTIRAMKC 723
BLAST of Tetratricopeptide repeat domain 17 vs. TrEMBL
Match: A0A3S1B591 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_012014 PE=4 SV=1) HSP 1 Score: 357.066 bits (915), Expect = 7.855e-100 Identity = 247/779 (31.71%), Postives = 419/779 (53.79%), Query Frame = 1
Query: 46 MKFLFPYSYIYVILFLMG--IIPPLPHINGYTHWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEISLYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRYQ-------------DIKISLIHEIENNATQERN-QIIYKTLGKLKPHQLV--------QCVISDLLTKEESVCELSTESLITHI-FKDLNRSPSESNRQEFQSDKELFR----------PTRSRVYKTLRLEQYKPSE---YVHNI------NETSCKRLNCPRNYDXXXXXXXXXXXXKGFDLDNLLTTKQQLTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRS--NFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKL 2244
M F + + VI F++ II NG THW VT+ G ++ T S Y+LR+P++LV ++QE+ + ++++L +++ N++ + + + + + C++A K L EF L+ + +L LE KGI+ ++++ + ++ +QP C +F + FSM FEHLE ++ R+ L G PE+ L K A+ + +YGHLV +L + N SS W+LYNMAAFYWR+KG+ HA+EC+R ALH SP +D+AL+SL+NI H + ++ +A +L+ A+ +S +H LGNIYA LG++N S+ ++ N K + + +R + C +L +A+++Q + + + L++L+ +Q + + YQ ++KI+ H E +ER+ ++ L K QL C + D ++ +C S S F L+ + SE ++E Q++ E + P R +Y L+++++K S+ Y+ I +T K++ RN ++Y+SP +KGF++ LLT Q L EH LPWYPP C + + D + +L+ LK+ +SY+ + R + + + L V + E++GQRI+TA+K+ + WIL+N+AGLYWRI+GN ++C R S+ LSP +YRD+PLVNLA IL R+ R QDA+ ++ A ++ +EP +H L +L + A HH A+ + + + A+KC L
Sbjct: 1 MAFTVQPALVLVIGFVLQRCII-----TNGATHWIVTEDGRLQAQTDSVYNLRRPYDLVAFMKQEQRASMLNDLKMELLNRKDEIDRNEDRDSGLEQKFYKTNPDCIQAGKPLPEFDLYISTVLPLENKGIRPEEHID---VNGSPTSSPRQPDCTAFMDLEFSMHAFEHLEGLKARTNLTGSPELGL-KNAITHRESVDDYGHLVFEALMK--NKSS--WVLYNMAAFYWRIKGNPYHAVECIRRALHHSPRLQKDVALISLSNILHRARFSN-EAAILVHAALEVSKELNVNHFTLGNIYAVLGEYNKSIICFE------NTLKIQPDFEAASKRRHAVLCHSKLEMALEAQHRSLQRTLEDLKDYQRKHDLYQSQSDKLLAEQVPHEVKIAQHHAFEQQKMRERSVEMATSVLSVDKEEQLTDTNSPGDEHCRMVDRDGRQVVLCTWSRRSPTLDFNFAYLDEN-SEKRKEENQAETEEAKNDPKRPDYSQPMRPAMY--LKIKKHKTSDSDFYMSPIWPQKEECDTFVKKVPDARNL----TTVYLSPENKGFEVKALLTEAQGLEKLGEHPLPWYPPVCVPLLTLPDGS-----IALDRLKA---VSYEERSRIPLKYNDPSMRSILQSHVNDGMVTEEEVGQRILTALKQNIEPQWILYNLAGLYWRIIGNNYHGIECIRRSIYLSPPQYRDIPLVNLANILYRYGRYQDAIVVMWDAITVNDAEPSSHFLMGHLLWATHNYTGAAHHYHEALAADPDYSLALGAVRAMKCYL 744 HSP 2 Score: 82.4185 bits (202), Expect = 5.818e-12 Identity = 44/151 (29.14%), Postives = 81/151 (53.64%), Query Frame = 1
Query: 3142 RYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
R S++D G ++ + +N + W + ++ YWR+ G+ A C+ A+ +SP + V L++ +NIL+R A + H +L+ S+ V F + NI+A + ++NK+ + +E L ++ DFE A R ++ C + LE QH
Sbjct: 187 RESVDDYGHLVFEALMKNKSSWVLYNMAAFYWRIKGNPYHAVECIRRALHHSPRLQKDVALISLSNILHRARFSNEAAILVHAALEV--SKELNVNHFTLGNIYAVLGEYNKSIICFENTLKIQPDFEAASKRRHAVLCHSKLEMALEAQH 335 HSP 3 Score: 79.337 bits (194), Expect = 5.354e-11 Identity = 81/396 (20.45%), Postives = 147/396 (37.12%), Query Frame = 1
Query: 2533 SNLHIQDHDCLLTNDSARSVGCHRNE-----------------EIYAASQNAFNFLAELRAVLKSISTQNMNNLTAKPLSVNKHLCHNDP---SKSTSKDDTNQSRSERTN-----------------------DIQETIINLISSRVVINPLAPEDCEHVAPFDFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTPKGTNFLRQIVDKYKI----DIETSQYSKIPEYNLHTSFLKTFDDRY-SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQ 3576
S + + DC++ ND ++SVGC R+E + + + E + +N P K P K SK + + + E+ ++ ET ++L+ V+ A D + D + ++S TM I + LD T L + P C + +R + + D+E + + L+T + + ++ G R+ + +N T W ++ YW+V G A CL++A+ P + L++ A L + A+ SL D + WI + +ANI+ ME W A LFY++ L +E R+++I C+ + Q
Sbjct: 925 SEMQVDAEDCIIFNDGSKSVGCSRDEFRTYVEDLHRNIHQFEQKFSSETGQPVQCSIEFHEAEPGGTCGGINLPPRGPDGKKKQGRPKKPLSGQKKESKGEQPEGKQEKKRQVLAPPSLSQPPRGGLKIPAPDFEMPETDVHLLKLGVLRVRKADCDQPDIEALDLAHFPSTFISPGTMGIRLSDHLD-FTETILVEKQKIPMCHTDLISPVRALEHLPGVAGVGDMEVAMPGTSTDLQQLEHILQTLNTEFETISTAGTRIANALAKNTTSWVANLLASYYWKVQGRGDSALGCLKVALTYVPYPYRYCPLLSLAIYLQQSGHPNEAVVACSASLDV-DREIWIAH-YTLANIYCLMESWANAALFYQSTLGFDPHHKETQTRLRAILCRGLAKQ 1317 HSP 4 Score: 65.0846 bits (157), Expect = 1.325e-6 Identity = 53/231 (22.94%), Postives = 103/231 (44.59%), Query Frame = 1
Query: 2896 DFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTPKGTNFLRQIVDKYKID----IETSQYSKIP-EYNLHT--SFLKTF--DDRYSLEDIGKRLYTGIEQN-ATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQC 3558
D + T +Y+S V +LL H P+ P L +D + + S+IP +YN + S L++ D + E++G+R+ T ++QN W + ++ YWR+ G+ C+ ++ SP + + LVN ANILYR + + A+ + ++ D++ FL+ ++ + A Y L+ D+ A+ +++++C
Sbjct: 514 DARNLTTVYLSPENKGFEVKALLTEAQGLEKLGEHPLPWYPPVCVPLLTLPDGSIALDRLKAVSYEERSRIPLKYNDPSMRSILQSHVNDGMVTEEEVGQRILTALKQNIEPQWILYNLAGLYWRIIGNNYHGIECIRRSIYLSPPQYRDIPLVNLANILYRYGRYQDAIVVMWDAITVNDAEP--SSHFLMGHLLWATHNYTGAAHHYHEALAADPDYSLALGAVRAMKC 742
BLAST of Tetratricopeptide repeat domain 17 vs. TrEMBL
Match: A0A0B7BD55 (Uncharacterized protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF181761 PE=4 SV=1) HSP 1 Score: 350.517 bits (898), Expect = 1.342e-99 Identity = 248/787 (31.51%), Postives = 407/787 (51.72%), Query Frame = 1
Query: 67 SYIYVILFLMGIIPPLPHINGYTHWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDY--LNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEISLYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRYQDIKISLIHEIENNATQERNQIIYKTLG-KLKPHQLVQ-CVISDLLTKEESVCELSTES-LITHIFKDLNRSPSESNRQEFQSDKELFRPTR---------SRVYKTLRLEQYK------------PSEYVHNINETSCKRLNCPRNYDXXXXXXXXXXXXKGFDLDNLLTTKQQLTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRS--NFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKLCRSY---------NSSDSHSDVVNKNFEMRENI 2316
S I ++L I+ NG THW VT+ G I+ S Y+LR+P++LV ++QE + ++ +L +++ N++ + + + + C++A K L EF L+ + +L LE KGI+ ++ LN + TN + P C F + +FSM FEHLE ++ RS L G PE+ L K A+ +YGHLV +L N + +WILYNMAAFYWR+KG+ A+EC+R ALH SP +D+AL+SLANI H + ++ +A +L+ A+ +S +H LGNIYA LG++N S+ ++ N K + + +R + C +L +A+++Q + + + L +L+ +Q + + YQ L+ E + + + Y+ L + K ++ + C + D K+ +C S S + F L +P ++N + E F P + S+ KT +YK PS +I +T K++ RN ++Y+SP +KGF++ LLT Q L EH LPWYPP C + + + P + D L+S +SY + R + + + + LL V + E++GQRI++A+K+ + WIL+N+AGLYWRI+GN ++C R ++ LSP++YRDVPLVNLA IL R+ R DA+ +++ A I+ +EP +H L +L A HH + + + + A+KC L Y + ++SHS+ K E +
Sbjct: 3 STITMVLLASFILQRCTITNGSTHWMVTEDGRIQSQADSVYNLRRPYDLVAFMKQEDRASMLNILKKELLTRKDEIDKNEDRDTGLEQKFYRTNPDCIEAGKPLPEFDLYISTVLPLENKGIRAEEHIDLNGSPSTNP-----RSPDCTVFTDLDFSMHAFEHLEGMKARSNLSGSPELGL-KNAITHRENVDDYGHLVYEAL----NKNKTSWILYNMAAFYWRIKGNPYQAVECIRRALHHSPRLQKDVALISLANILHRARFSN-EAAILVHAALEVSKELNVNHFTLGNIYAVLGEYNKSIICFE------NTLKIQPDFEAASKRKHAVLCHSKLEMALEAQHRSLQRTLKDLKDYQRKHDLYQMQSDKLLAEQVPHEVKVAQHLAYEQLKMREKSAEMDEYCRMVDREGKQVLLCTWSRRSPTLDFDFAFLEEAPEKTNDENIS---EKFMPGQKTNSKSPNYSQPVKTPLYSKYKKHKNTEADPYMLPSWPTKDICDTYVKKVPDSRNL----TTVYLSPENKGFEVKELLTEAQGLEQEGEHPLPWYPPVCVPLMELAEGNPT-VYDHLKS------VSYAERSRIPLKYNDPSMRKILLDHVNNGFVTEEEVGQRILSALKQNIGPQWILYNLAGLYWRIIGNNYHGIECIRRAIYLSPVQYRDVPLVNLANILYRYGRYDDAIIIMKDALDINDAEPASHFLLGHLLWATRNYTGAAHHYQEVLAADENYPGALDTIRAMKCYLKYHYAAQSAAPQESPANSHSNCQPKPAETESRV 758 HSP 2 Score: 87.8113 bits (216), Expect = 1.130e-13 Identity = 52/172 (30.23%), Postives = 88/172 (51.16%), Query Frame = 1
Query: 3079 SQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
S S PE L + R +++D G +Y + +N T W + ++ YWR+ G+ QA C+ A+ +SP + V L++ ANIL+R A + H +L+ S+ V F + NI+A + ++NK+ + +E L ++ DFE A R ++ C + LE QH
Sbjct: 168 SNLSGSPELGLKNAITH----RENVDDYGHLVYEALNKNKTSWILYNMAAFYWRIKGNPYQAVECIRRALHHSPRLQKDVALISLANILHRARFSNEAAILVHAALEV--SKELNVNHFTLGNIYAVLGEYNKSIICFENTLKIQPDFEAASKRKHAVLCHSKLEMALEAQH 333 HSP 3 Score: 65.4698 bits (158), Expect = 1.027e-6 Identity = 36/136 (26.47%), Postives = 70/136 (51.47%), Query Frame = 1
Query: 3154 EDIGKRLYTGIEQN-ATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQC 3558
E++G+R+ + ++QN W + ++ YWR+ G+ C+ A+ SP + V LVN ANILYR + + A+ I +L D++ FL+ ++ + A Y+ L+ ++ A+ I++++C
Sbjct: 590 EEVGQRILSALKQNIGPQWILYNLAGLYWRIIGNNYHGIECIRRAIYLSPVQYRDVPLVNLANILYRYGRYDDAIIIMKDALDINDAEP--ASHFLLGHLLWATRNYTGAAHHYQEVLAADENYPGALDTIRAMKC 723
BLAST of Tetratricopeptide repeat domain 17 vs. TrEMBL
Match: A0A2T7PK80 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_05063 PE=4 SV=1) HSP 1 Score: 327.791 bits (839), Expect = 4.869e-90 Identity = 241/763 (31.59%), Postives = 405/763 (53.08%), Query Frame = 1
Query: 124 NGYTHWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRI--ELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEISLYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRYQDIKISLIHEIENNATQERNQIIYK-TLGKLKPHQLVQ-CVISDLLTKEESVCELSTESL-ITHIFKDLNRSPSESN----------RQEFQSD-KELFRPTRSRVYKTLR--LEQYKPSEYV------HNINETSCKRLNCPRNYDXXXXXXXXXXXXKGFDLDNLLTTKQQLTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNF--AEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAAN-LYRDNNELMLAYHH---LEIAILQNSTLKVNNVDLDAIKCKLCRSYNSSDSHSDVVNKNFEMRENITQ 2322
+G THW VT+ G ++ S ++LR+P++LV ++QE+ + + EL + D +++ + + + ++ C++A K L EF L+ + +L LE KGI+ ++++ NI A P C++ + +FSM FEHLE +++R L G PE+ L K A+ EYGHLV +L N ++ +WILYNMAAFYWR+KG AIEC+R ALH SP +D+AL+SLANI H + ++ +A +L+ +A+ +S +H LGNIYA LG++N S+ ++ N K + + + +R + C +L A+++Q + + K L EL+ +Q + + YQ L E + +I Y+ + K +++ + C + D K+ +C S S + F L+ P + N R+ F D + +P R + R + +++ SE + + +T +++ PRN ++ LS KGF++ LLT Q L EH LPWYPP C V + +L P ++ + LKS +SY + R ++ + + LL+ V G ++ E++GQRI+TAI++ + W+L+N+AGLYWR++GN ++C R ++ LSP E+RDVPL NLA IL R+ R DA+ +++ A I EP +++L A+ L+ +N +H+ LEI N L A++C L + + ++ S + V + N Q
Sbjct: 22 SGSTHWIVTEDGRLQSQADSVFNLRRPYDLVAFMRQEERAYMLGNLKKELLSRKSEIDRHEDRDSAAGLEQKFYQTDPDCIEAGKPLPEFDLYISTVLPLENKGIRPEEHVDLNAPLNIPPIA---PDCQAVTSLDFSMHAFEHLEGLKDRRNLSGTPELGL-KNAITHRENVDEYGHLVYEAL----NKNTTSWILYNMAAFYWRIKGEPFQAIECIRRALHYSPRHQKDVALISLANILHRARYSN-EAAILVHSALDLSRELNVNHFTLGNIYAVLGEYNKSIICFE------NTLKIQPEFEAAAKRKHAVLCHSKLEAALEAQHRALQKTLKELKDYQKKHDIYQTQNEKLATEQVLTEVKISQRIAYEHSKMKDSSNEMGEYCRMVDRDGKQVLLCTWSRRSADLDFDFAFLDNPPKKENQQEEEEENGFRKSFTKDLPDYTKPVRPPRFSKNRPSVPKFQNSEGMMEEWPSKDECDTYVQKVPDPRNLSTVFLSPEN----KGFEVKTLLTEAQGLIPDVEHPLPWYPPVC---VPLMEL-PEGSENTYDHLKS---VSYAERSRIPLKHSDPSMRKTLLEHVNGGSVTEEEVGQRILTAIRQMIGPQWVLYNLAGLYWRVIGNSYHGIECLRRALHLSPPEFRDVPLNNLANILYRWGRIDDALAVMKDAVNISDVEPASNLLYAHLLWASSNHTGAVWHYRHALEIQPDLNEAFST----LRALRCYL-KYHQAAQSAAPVETPTTPLAPNCGQ 753 HSP 2 Score: 127.102 bits (318), Expect = 1.146e-25 Identity = 102/362 (28.18%), Postives = 162/362 (44.75%), Query Frame = 1
Query: 2533 SNLHIQDHDCLLTNDSARSVGCHRNE--EIYAASQ-----NAFNFLAELRAVLKSISTQNMNN--LTAKPLSVNKHLCHNDPSKSTSKDDTNQSRSERTNDIQETIINLISSRVVINPLAPEDCEH--VAPFDFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTPKGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYS-LEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNL 3582
+LH++ H+C++ ND ARS+GC R+E + SQ A N L L LK+ M + L +P + K P S K E DI I+ + E+C + FDFK T ++ + IN+ +D G + NF+ P N TS L+T L +G R+ + ++ T W++A ++ YWRV G+ A NCL LA+ NSP + L++ ANIL++ L+ A+ + +L S+ ++ F +ANI+A E+W KA FYE+ L+L+ F+ A YR+++I CQ + Q +
Sbjct: 905 GDLHVEPHECVIFNDGARSLGCSRSEFRTYFDNSQMVKDMEAINTL--LSQELKTCCQVKMQDSALPQQPTCMKKKSLPF-PETSVGKKSEQVGSDEDLPDISIYIVGRYHLQ-----WNKEECRNGDYMNFDFKGVTSTWLPITETGINLSDYIDF---GIVVKH-----------NFME------------------PACNEETSVLQTLGGEIDPLGVVGTRIAKALNEHPTSWELANLAALYWRVEGNPVNAVNCLRLALANSPSNARSIALISLANILHQAGHLDDAIIVMAAALDV--SKEVVIAQFTLANIYAAKEEWTKAAQFYESTLALQPTFQPAKYRLQAILCQGQISQAI 1224 HSP 3 Score: 82.0333 bits (201), Expect = 8.372e-12 Identity = 49/169 (28.99%), Postives = 85/169 (50.30%), Query Frame = 1
Query: 3088 SKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
S PE L + R ++++ G +Y + +N T W + ++ YWR+ G+ QA C+ A+ SP + V L++ ANIL+R A + H +L S+ V F + NI+A + ++NK+ + +E L ++ +FE A R ++ C + LE QH
Sbjct: 173 SGTPELGLKNAITH----RENVDEYGHLVYEALNKNTTSWILYNMAAFYWRIKGEPFQAIECIRRALHYSPRHQKDVALISLANILHRARYSNEAAILVHSALDL--SRELNVNHFTLGNIYAVLGEYNKSIICFENTLKIQPEFEAAAKRKHAVLCHSKLEAALEAQH 335 HSP 4 Score: 81.2629 bits (199), Expect = 1.581e-11 Identity = 48/149 (32.21%), Postives = 78/149 (52.35%), Query Frame = 1
Query: 652 LVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDS 1098
+V + + + N+ +W L N+AA YWRV+G+ +A+ CLR AL SP + IAL+SLANI H DAI++M A+ +S L NIYA+ ++ + Y+ +L + + + R+ + C ++S AI S
Sbjct: 1085 VVGTRIAKALNEHPTSWELANLAALYWRVEGNPVNAVNCLRLALANSPSNARSIALISLANILHQAGHLD-DAIIVMAAALDVSKEVVIAQFTLANIYAAKEEWTKAAQFYESTLAL------QPTFQPAKYRLQAILCQGQISQAIPS 1226 HSP 5 Score: 67.0106 bits (162), Expect = 3.084e-7 Identity = 52/173 (30.06%), Postives = 78/173 (45.09%), Query Frame = 1
Query: 1738 NLISYQNKG---RSNFAEKHLLQE--LLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCK 2241
NL Y + G + NF E +E +L+ + G L +G RI A+ S W L N+A LYWR+ GN A++C RL++ SP R + L++LA IL + DA+ ++ A + AN+Y E A E + T + L AI C+
Sbjct: 1046 NLSDYIDFGIVVKHNFMEPACNEETSVLQTLGGEIDPLGVVGTRIAKALNEHPTS-WELANLAALYWRVEGNPVNAVNCLRLALANSPSNARSIALISLANILHQAGHLDDAIIVMAAALDVSKEVVIAQFTLANIYAAKEEWTKAAQFYESTLALQPTFQPAKYRLQAILCQ 1217 HSP 6 Score: 65.4698 bits (158), Expect = 1.098e-6 Identity = 44/169 (26.04%), Postives = 76/169 (44.97%), Query Frame = 1
Query: 3070 IETSQYSKIPEYNLHTSFLKTF-----DDRYSLEDIGKRLYTGIEQN-ATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQC 3558
+ ++ S+IP + S KT + E++G+R+ T I Q W + ++ YWRV G++ CL A+ SP V L N ANILYR +++ AL + ++ D + L A++ A Y L ++ D EA +++++C
Sbjct: 560 VSYAERSRIPLKHSDPSMRKTLLEHVNGGSVTEEEVGQRILTAIRQMIGPQWVLYNLAGLYWRVIGNSYHGIECLRRALHLSPPEFRDVPLNNLANILYRWGRIDDALAVMKDAVNISDVEP--ASNLLYAHLLWASSNHTGAVWHYRHALEIQPDLNEAFSTLRALRC 726
BLAST of Tetratricopeptide repeat domain 17 vs. TrEMBL
Match: K1S1I1 (Tetratricopeptide repeat protein 17 OS=Crassostrea gigas OX=29159 GN=CGI_10026556 PE=4 SV=1) HSP 1 Score: 327.791 bits (839), Expect = 2.173e-89 Identity = 226/746 (30.29%), Postives = 398/746 (53.35%), Query Frame = 1
Query: 73 IYVILFLMGIIPPLPHINGYTHWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEISLYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRYQDIKISLIHEIENNATQERNQIIYKTLGKLKPHQLVQ--CVISDLLTKEESVCELSTESLITH----IFKDLNRSP--SESNRQEFQSDK----ELFRPTRSRVY---KTLRLEQYKPSEY---VHNINETSCKRLNCPRNYDXXXXXXXXXXXXKGFDLDNLLTTKQQLTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRS--NFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLE--IAILQNSTLKVNNVDLDAIKCKL 2244
+ V+++++ I P G +HW VT+ G I+ + +++++P++LV ++QE+ +++++ +L +++ N++ + + + ++ C+ A K L EF L+ + +L LE KGI+ D+++ + + L+ P CE + FSM FEHLE +++R L G PE+ L K A+ H + EYGH V +L ++ +W+LYNMAAF+WR+KG IECLR ALH SP ++D+AL+SLAN+ H + ++ +A +++ A+ +S +H LGNIYA + ++N S+ ++ N K + K ER ++ C +L A+++Q + + K L++L+ +Q + + +Q L+ E + + +++L + + + C + D ++ +C +S+ +F D + R+E D+ + +P R+ +Y K L +Y + + +T +++ PRN ++Y+SP +KGF++ LLT Q L EH LPWYPP C + + P + + +KS ++Y+ + R + + LL V + +E+IGQR++TA+K+++ W+L+N+AGLYWRI+GN Q ++C R S+ L EY+DVPLVNLA IL R+ R +DA+ ++ A ++ EPE+H ANL A H E + IL S NN L AI+C L
Sbjct: 4 MLVVVYILHHISP---SGGSSHWVVTEDGRIQAQLDTVFNMKRPYDLVAFMRQEERSGMLEKLKDELLSRKDEIDKNEDRDTGLEQRFYKTDPDCLMAVKPLPEFDLYISTVLPLENKGIRPEDHID---MKKKLESPLKPPNCELIGDLPFSMDAFEHLEGMKDRLSLTGTPELGL-KNAITYHDSVDEYGHRVQEAL----QANTTSWVLYNMAAFFWRIKGDPYLTIECLRRALHYSPRMHKDVALISLANVLHRARYSN-EAAIVVHAALDVSKELNVNHFTLGNIYAVMAEYNKSVICFE------NTLKIQPDFKAAAERKYAVLCHAKLEAALEAQHRSLQKTLNDLKDYQRKHDFWQQQNEKLLAEQVPANIKINQHVAHESLRMQQANVEIGEFCQMVDRDGRQVLMCTWGKKSMEDEMDFTMFGDFEHGDLIDINKREEEDVDESPIIDYSKPVRAPLYTNEKKLEAPKYNNPDSDWPAKDECDTYVQKVPDPRNL----STIYLSPENKGFEVKALLTEAQNLQQEDEHPLPWYPPVCVPLMEV----PEGQKKTYDHIKS---VTYEERTRIPLKLNDPSMFPILLSHVND-GIAIEEIGQRLLTALKQKIGPGWVLYNLAGLYWRIIGNNYQGVECIRRSLYLVQEEYKDVPLVNLANILYRWGRFEDAVTVMRDALAVNDLEPESHYFYANLLWATKNYTGAVKHYEKSLDILPESQDTFNN--LRAIRCYL 717 HSP 2 Score: 100.523 bits (249), Expect = 2.203e-17 Identity = 54/154 (35.06%), Postives = 82/154 (53.25%), Query Frame = 1
Query: 3124 LKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE 3585
L D+ +E IG R+ + +N T W +A+ + YWRV GDA +A +CL LA+ +P + L++ ANIL+R L A+ T+ +L P + QW+KAT+FYE+ L L++ F A R+K I+C + VMQ E
Sbjct: 1235 LGGGGDKQPVEVIGTRIAQALRKNMTSWVLASTAALYWRVEGDASRAIDCLRLALTTAPPDVQDTALISVANILHRSGYLNDAIVATNMALDVP----------------VKLGQWDKATMFYESTLGLQSSFTAAKQRLKKIKC-RFVMQRPE 1371 HSP 3 Score: 85.8853 bits (211), Expect = 5.805e-13 Identity = 50/169 (29.59%), Postives = 85/169 (50.30%), Query Frame = 1
Query: 3088 SKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
+ PE L + T+ D S+++ G R+ ++ N T W + ++ +WR+ GD CL A+ SP H+ V L++ AN+L+R A + H +L N V F + NI+A M ++NK+ + +E L ++ DF+ A R ++ C + LE QH
Sbjct: 167 TGTPELGLKNAI--TYHD--SVDEYGHRVQEALQANTTSWVLYNMAAFFWRIKGDPYLTIECLRRALHYSPRMHKDVALISLANVLHRARYSNEAAIVVHAALDVSKELN--VNHFTLGNIYAVMAEYNKSVICFENTLKIQPDFKAAAERKYAVLCHAKLEAALEAQH 329 HSP 4 Score: 78.5666 bits (192), Expect = 9.031e-11 Identity = 57/194 (29.38%), Postives = 91/194 (46.91%), Query Frame = 1
Query: 487 LQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEISL----YKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNP-NKDKIKLKDIEERI 1053
L++P C + F+ + + L +RN+ L PE L K+ P E ++ + + Q + +W+L + AA YWRV+G A AI+CLR AL T+P QD AL+S+ANI H ++ L+ ++ N L P LGQ++ + Y+ L + K +LK I+ R
Sbjct: 1193 LEEPVCITDFHSALEL---DMLPGVRNKKHLHYHPETVLKEVLQKLGGGGDKQPVE---VIGTRIAQALRKNMTSWVLASTAALYWRVEGDASRAIDCLRLALTTAPPDVQDTALISVANILH--RSGYLNDAIVATNMALDVP-------------VKLGQWDKATMFYESTLGLQSSFTAAKQRLKKIKCRF 1365 HSP 5 Score: 75.0998 bits (183), Expect = 1.300e-9 Identity = 42/133 (31.58%), Postives = 78/133 (58.65%), Query Frame = 1
Query: 1696 PLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMR--LEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKI 2088
P+ + D +L+ D L +NK ++ + +L+E+L+ + G + +E IG RI A+ R+ M++W+L + A LYWR+ G+ ++A+DC RL++ +P + +D L+++A IL R DA+ A +
Sbjct: 1196 PVCITDFHSALELDMLPGVRNKKHLHYHPETVLKEVLQKLGGGGDKQPVEVIGTRIAQAL-RKNMTSWVLASTAALYWRVEGDASRAIDCLRLALTTAPPDVQDTALISVANILHRSGYLNDAIVATNMALDV 1327 HSP 6 Score: 67.781 bits (164), Expect = 1.866e-7 Identity = 40/151 (26.49%), Postives = 74/151 (49.01%), Query Frame = 1
Query: 3121 FLKTFDDRYSLEDIGKRLYTGIEQN-ATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQY----PDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQC 3558
L +D ++E+IG+RL T ++Q W + ++ YWR+ G+ Q C+ ++ E ++ V LVN ANILYR + E A+ + +L P+S + AN+ + + A YE L + + ++ +++I+C
Sbjct: 571 LLSHVNDGIAIEEIGQRLLTALKQKIGPGWVLYNLAGLYWRIIGNNYQGVECIRRSLYLVQEEYKDVPLVNLANILYRWGRFEDAVTVMRDALAVNDLEPESH------YFYANLLWATKNYTGAVKHYEKSLDILPESQDTFNNLRAIRC 715
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Cavefish
Match: ttc17 (tetratricopeptide repeat domain 17 [Source:NCBI gene;Acc:569538]) HSP 1 Score: 150.214 bits (378), Expect = 3.174e-36 Identity = 99/350 (28.29%), Postives = 182/350 (52.00%), Query Frame = 1
Query: 133 THWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGV------PEISLYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
THW VT+ G I+ S +L+ P +LV +QQE + +++ +E +L ++ N++ + + + + CV A L + L+ +SLE+KGI DY++ + + L++P C +S+ F+HL ++ R+ L P + + Q L E GH + L + +S +W+LY++A+FYWR+K + A++C+ ALH SP +++D+ALV++ANI H ++ AI+ L + TSH+ LGNIYA LG++N+S+ Y+ A + + + R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 58 THWVVTEDGKIQQQVDSPLNLKHPHHLVLFMQQETRVNYLKNLEKQLVAQKIHIEENEDRDTGLEQRHYKEDPDCVTAKVPLGDLDLYDGTFISLESKGINPEDYVDSVLPLP---SDLEKPDCAEILELPYSIHAFQHLRGVQERANLTSPLLSKDDPIFASLSHKLGQRLD--EVGHRIQQGLLR----NSSSWVLYDLASFYWRMKNEPRRAVDCVVRALHFSPRQHKDVALVNMANILHRAHFSADAAILAHAALDLTTDLLTSHY-TLGNIYAMLGEYNHSVLCYEQAL------QAQPGFEQALRRKHAVLCQQKLEQRLEAQHRSLQRTLNELKEYQKQHDHY 391 HSP 2 Score: 111.309 bits (277), Expect = 3.045e-24 Identity = 65/215 (30.23%), Postives = 112/215 (52.09%), Query Frame = 1
Query: 409 LSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNF--SMCCFEHLETIRNRSMLEGVPEISLYKIAM---PQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
L++ AK I ++++ A LQ+P E N N SM +HL + NR + E L ++ + +P + V + + + + +W+L +MAA YWRVKG K A++CLR AL+ +P +D+ L+SLANIF + DA+ + + A+ I+PHF +H L N+Y ++ +F ++ Y+ L + P KD+++
Sbjct: 863 LAVSAKNIDITEHIDFA-------TPLQEPAVEPVCNANLPASMHTLDHLGGVANRGSIHYTGESQLKEVLQNLGKDNFSPQSFEQ-VGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAVDCLRQALNYAPHHMKDVPLISLANIFQNARLWG-DALTVARMAVEIAPHFVVNHFTLANVYIAMEEFEKAMRWYESTLKLQPEFGPAKDRLR 1068 HSP 3 Score: 94.3597 bits (233), Expect = 5.538e-19 Identity = 62/236 (26.27%), Postives = 116/236 (49.15%), Query Frame = 1
Query: 2863 APEDCEHVAPFDFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCT---PKGTNFLRQIVD-KYKIDIETSQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQC 3558
PE+C+ D T +++++ I++ +D TP L P C P + L + + I + S++ E L F + S E +G R+ +E+N T W +++++ YWRV G ++A +CL A+ +P + V L++ ANI AL + +++ + +++V F +AN++ ME++ KA +YE+ L L+ +F A R+++IQC
Sbjct: 843 GPEECQRTRRVDLTTVASTWLAVSAKNIDITEHIDFATP--LQEPAVEPVCNANLPASMHTLDHLGGVANRGSIHYTGESQLKEV-LQNLGKDNFSPQ-SFEQVGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAVDCLRQALNYAPHHMKDVPLISLANIFQNARLWGDALTVARMAVEI--APHFVVNHFTLANVYIAMEEFEKAMRWYESTLKLQPEFGPAKDRLRTIQC 1072 HSP 4 Score: 84.3445 bits (207), Expect = 5.132e-16 Identity = 65/243 (26.75%), Postives = 115/243 (47.33%), Query Frame = 1
Query: 2896 DFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTPKGTNFLRQIVD-KYKIDIETSQYSKIPEYNLHTSFLKTFDDRYS---------LEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
D Y ++SL + IN +DS+ P L S + P C +I++ Y I NL + L D ++ L+++G R+ G+ +N++ W + ++ YWR+ + ++A +C+ A+ SP H+ V LVN ANIL+R + +A + + + + + NI+A + ++N + L YE L + FE+A+ R ++ CQQ + Q LE QH
Sbjct: 141 DLDLYDGTFISLESKGINPEDYVDSVLP--LPSDLEKPDCA--------EILELPYSIHAFQHLRGVQERANLTSPLLSKDDPIFASLSHKLGQRLDEVGHRIQQGLLRNSSSWVLYDLASFYWRMKNEPRRAVDCVVRALHFSPRQHKDVALVNMANILHRAHF--SADAAILAHAALDLTTDLLTSHYTLGNIYAMLGEYNHSVLCYEQALQAQPGFEQALRRKHAVLCQQKLEQRLEAQH 371 HSP 5 Score: 74.7146 bits (182), Expect = 5.410e-13 Identity = 46/134 (34.33%), Postives = 74/134 (55.22%), Query Frame = 1
Query: 1792 LQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAAN--LYRDN--NELMLAYHHLEIA 2181
+Q LL+ G + LE G I A+++ + W+L N AGL+WR GN +AL C R ++ +P ++R +PLVN A +L+ ++A L++ A +++ SEP T + N L R N L L H L ++
Sbjct: 534 VQVLLRRSGGWS--LEQTGALITHAMEKMSVPRWLLQNEAGLFWRAQGNGTRALQCLRQALHSAPPQHRGIPLVNTANLLLHHGLRREAQTLLQQALELNTSEPHTVLSMVNVQLTRGNLTGALALFRHALSLS 665 HSP 6 Score: 68.9366 bits (167), Expect = 3.227e-11 Identity = 47/173 (27.17%), Postives = 81/173 (46.82%), Query Frame = 1
Query: 1735 DNLISYQNKGRSNFAEKHLLQELLKLVQGVNMR---LEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKL 2244
D+L N+G ++ + L+E+L+ + N E +G RI +++ ++W+L ++A LYWR+ G +A+DC R ++ +P +DVPL++LA I + DA+ + A +I H AN+Y E A E + L I+C L
Sbjct: 903 DHLGGVANRGSIHYTGESQLKEVLQNLGKDNFSPQSFEQVGTRIAKVLEKN-QTSWVLSSMAALYWRVKGQGKKAVDCLRQALNYAPHHMKDVPLISLANIFQNARLWGDALTVARMAVEIAPHFVVNHFTLANVYIAMEEFEKAMRWYESTLKLQPEFGPAKDRLRTIQCYL 1074 HSP 7 Score: 59.6918 bits (143), Expect = 1.861e-8 Identity = 27/72 (37.50%), Postives = 46/72 (63.89%), Query Frame = 1
Query: 1822 VNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIR 2037
+ RL+++G RI + R S+W+L+++A YWR+ +A+DC ++ SP +++DV LVN+A IL R
Sbjct: 222 LGQRLDEVGHRIQQGLLRN-SSSWVLYDLASFYWRMKNEPRRAVDCVVRALHFSPRQHKDVALVNMANILHR 292 HSP 8 Score: 59.3066 bits (142), Expect = 2.483e-8 Identity = 32/103 (31.07%), Postives = 57/103 (55.34%), Query Frame = 1
Query: 688 SSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILIS---PH----FTSHHMILGNIYASLGQFNNSL 975
S W+L N A +WR +G+ A++CLR ALH++P +++ I LV+ AN+ L +A L++ A+ ++ PH + + GN+ +L F ++L
Sbjct: 561 SVPRWLLQNEAGLFWRAQGNGTRALQCLRQALHSAPPQHRGIPLVNTANLL-LHHGLRREAQTLLQQALELNTSEPHTVLSMVNVQLTRGNLTGALALFRHAL 662 HSP 9 Score: 53.1434 bits (126), Expect = 1.981e-6 Identity = 39/159 (24.53%), Postives = 70/159 (44.03%), Query Frame = 1
Query: 3145 YSLEDIGKRLYTGIEQ-NATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQM--VMQNLEQH*CQDHVM 3612
+SLE G + +E+ + W + + +WR G+ +A CL A+ ++P H + LVN AN+L A + ++L+ S+ V+ + N+ T A + LSL A + + ++C Q + NL+ CQ V+
Sbjct: 544 WSLEQTGALITHAMEKMSVPRWLLQNEAGLFWRAQGNGTRALQCLRQALHSAPPQHRGIPLVNTANLLLHHGLRREAQTLLQQALELNTSEPHTVLSMV--NVQLTRGNLTGALALFRHALSLSAGCSQCRASLPLLRCLQFYPFLYNLQHQPCQQVVV 700
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Cavefish
Match: ttc17 (tetratricopeptide repeat domain 17 [Source:NCBI gene;Acc:569538]) HSP 1 Score: 146.747 bits (369), Expect = 4.618e-35 Identity = 99/350 (28.29%), Postives = 182/350 (52.00%), Query Frame = 1
Query: 133 THWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGV------PEISLYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
THW VT+ G I+ S +L+ P +LV +QQE + +++ +E +L ++ N++ + + + + CV A L + L+ +SLE+KGI DY++ + + L++P C +S+ F+HL ++ R+ L P + + Q L E GH + L + +S +W+LY++A+FYWR+K + A++C+ ALH SP +++D+ALV++ANI H ++ AI+ L + TSH+ LGNIYA LG++N+S+ Y+ A + + + R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 69 THWVVTEDGKIQQQVDSPLNLKHPHHLVLFMQQETRVNYLKNLEKQLVAQKIHIEENEDRDTGLEQRHYKEDPDCVTAKVPLGDLDLYDGTFISLESKGINPEDYVDSVLPLP---SDLEKPDCAEILELPYSIHAFQHLRGVQERANLTSPLLSKDDPIFASLSHKLGQRLD--EVGHRIQQGLLR----NSSSWVLYDLASFYWRMKNEPRRAVDCVVRALHFSPRQHKDVALVNMANILHRAHFSADAAILAHAALDLTTDLLTSHY-TLGNIYAMLGEYNHSVLCYEQAL------QAQPGFEQALRRKHAVLCQQKLEQRLEAQHRSLQRTLNELKEYQKQHDHY 402 HSP 2 Score: 87.4261 bits (215), Expect = 6.310e-17 Identity = 43/145 (29.66%), Postives = 81/145 (55.86%), Query Frame = 1
Query: 3151 LEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE 3585
L+++G R+ G+ +N++ W + ++ YWR+ + ++A +C+ A+ SP H+ V LVN ANIL+R + +A + + + + + NI+A + ++N + L YE L + FE+A+ R ++ CQQ + Q LE
Sbjct: 237 LDEVGHRIQQGLLRNSSSWVLYDLASFYWRMKNEPRRAVDCVVRALHFSPRQHKDVALVNMANILHRAHF--SADAAILAHAALDLTTDLLTSHYTLGNIYAMLGEYNHSVLCYEQALQAQPGFEQALRRKHAVLCQQKLEQRLE 379 HSP 3 Score: 79.337 bits (194), Expect = 2.215e-14 Identity = 47/153 (30.72%), Postives = 80/153 (52.29%), Query Frame = 1
Query: 1795 QELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKLCRS 2253
Q LL+ G + LE G I A+++ + W+L N AGL+WR GN +AL C R ++ +P ++R +PLVN A +L+ ++A L++ A +++ SEP T + N+ L A +A+ +++ + L A C CR+
Sbjct: 613 QVLLRRSGGWS--LEQTGALITHAMEKMSVPRWLLQNEAGLFWRAQGNGTRALQCLRQALHSAPPQHRGIPLVNTANLLLHHGLRREAQTLLQQALELNTSEPHTVLSMVNVQLTRGNLTGA-----LALFRHA------LSLSA-GCSQCRA 751 HSP 4 Score: 65.0846 bits (157), Expect = 4.596e-10 Identity = 40/138 (28.99%), Postives = 71/138 (51.45%), Query Frame = 1
Query: 1687 DLTPLDLIDSLESLKSD--------------NLISYQN-KG---RSNFAEKHLLQE---LLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIR 2037
+ P D +DS+ L SD ++ ++Q+ +G R+N L ++ L + RL+++G RI + R S+W+L+++A YWR+ +A+DC ++ SP +++DV LVN+A IL R
Sbjct: 167 GINPEDYVDSVLPLPSDLEKPDCAEILELPYSIHAFQHLRGVQERANLTSPLLSKDDPIFASLSHKLGQRLDEVGHRIQQGLLRN-SSSWVLYDLASFYWRMKNEPRRAVDCVVRALHFSPRQHKDVALVNMANILHR 303 HSP 5 Score: 59.3066 bits (142), Expect = 2.988e-8 Identity = 32/103 (31.07%), Postives = 57/103 (55.34%), Query Frame = 1
Query: 688 SSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILIS---PH----FTSHHMILGNIYASLGQFNNSL 975
S W+L N A +WR +G+ A++CLR ALH++P +++ I LV+ AN+ L +A L++ A+ ++ PH + + GN+ +L F ++L
Sbjct: 639 SVPRWLLQNEAGLFWRAQGNGTRALQCLRQALHSAPPQHRGIPLVNTANLL-LHHGLRREAQTLLQQALELNTSEPHTVLSMVNVQLTRGNLTGALALFRHAL 740 HSP 6 Score: 55.8398 bits (133), Expect = 2.912e-7 Identity = 38/155 (24.52%), Postives = 68/155 (43.87%), Query Frame = 1
Query: 3145 YSLEDIGKRLYTGIEQ-NATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQM--VMQNLEQH*CQ 3600
+SLE G + +E+ + W + + +WR G+ +A CL A+ ++P H + LVN AN+L A + ++L+ S+ V+ + N+ T A + LSL A + + ++C Q + NL+ CQ
Sbjct: 622 WSLEQTGALITHAMEKMSVPRWLLQNEAGLFWRAQGNGTRALQCLRQALHSAPPQHRGIPLVNTANLLLHHGLRREAQTLLQQALELNTSEPHTVLSMV--NVQLTRGNLTGALALFRHALSLSAGCSQCRASLPLLRCLQFYPFLYNLQHQPCQ 774
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002304.1 (pep scaffold:Pmarinus_7.0:GL479761:24289:30515:-1 gene:ENSPMAG00000002095.1 transcript:ENSPMAT00000002304.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 86.2705 bits (212), Expect = 3.203e-19 Identity = 60/178 (33.71%), Postives = 89/178 (50.00%), Query Frame = 1
Query: 487 LQQPFCESFFNQNF--SMCCFEHLETIRNRSML----EGVPEISLYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL 1002
LQ+PF E N SM +HL + R L E L ++A L H VA+ + + + +W+L N+AA YWR++G + AI+CLR +LH +P +D+ALVSLAN+ L +A V+ A+ ISP + H LGN Y ++ +L Y A +L
Sbjct: 11 LQEPFSEPVCNPALPASMHTLDHLAGVGARGSLMYGGEKRLRGELERLAKAS-LGERRLEH-VATRIARAMEKNDTSWVLANLAALYWRIQGQGRRAIDCLRHSLHHAPHHMKDVALVSLANVL-LQARLGKEAQVVAGMAVHISPRNPTAHCTLGNAYLAMEDRQKALQCYGSALAL 185 HSP 2 Score: 73.9442 bits (180), Expect = 5.480e-15 Identity = 40/147 (27.21%), Postives = 77/147 (52.38%), Query Frame = 1
Query: 3151 LEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEI----THKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQN 3579
LE + R+ +E+N T W +A ++ YWR+ G ++A +CL ++ ++P + V LV+ AN+L + + A + H S + P + + N + ME KA Y + L+L+ ++ A+ R++++QC +V +N
Sbjct: 68 LEHVATRIARAMEKNDTSWVLANLAALYWRIQGQGRRAIDCLRHSLHHAPHHMKDVALVSLANVLLQARLGKEAQVVAGMAVHISPRNPTAH------CTLGNAYLAMEDRQKALQCYGSALALQPEYPTALERLRAVQCNILVYEN 208 HSP 3 Score: 71.633 bits (174), Expect = 3.296e-14 Identity = 43/121 (35.54%), Postives = 64/121 (52.89%), Query Frame = 1
Query: 1777 AEKHLLQELLKLVQGV--NMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLY 2133
EK L EL +L + RLE + RI A+++ S W+L N+A LYWRI G +A+DC R S+ +P +DV LV+LA +L++ + ++A + A I P H N Y
Sbjct: 47 GEKRLRGELERLAKASLGERRLEHVATRIARAMEKNDTS-WVLANLAALYWRIQGQGRRAIDCLRHSLHHAPHHMKDVALVSLANVLLQARLGKEAQVVAGMAVHISPRNPTAHCTLGNAY 166
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Nematostella
Match: EDO43200 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ97]) HSP 1 Score: 125.946 bits (315), Expect = 3.515e-29 Identity = 88/343 (25.66%), Postives = 164/343 (47.81%), Query Frame = 1
Query: 46 MKFLFPYS-----YIYVILFLMGIIPPLPHINGYTHWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESA-------------------CVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEISLYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL 1002
M +P+ I + F++ P + THW VT++G IE S + + +P++LV + +E+ ++ + K +Q ++ N +Q V+ + ES C K ++E ++ +++ KGI D++N L P C+ S+ F+HLE + R + V ++ + ++ +P ++ E+G S L + +S +W+L N+AA YWR GS I CLR+AL+ SPW ++D+AL SL + H T LDA+VL+ +++ I+ + H +LG +Y++L F+ + ++ T++
Sbjct: 1 MAAFYPWDSWRGLLILCVFFILLSSHP---CSAVTHWVVTENGRIEQQASSVFIMNRPYDLVAFMTKEQEVK-----KAKKDQEHEEVYKNFHHQKLVNHGTMKEESEIVTDSDEDQAKEFFAKDPFCNKVKYRVTELSIDLLNVVPFAKKGINIEDHVN----LKGKAPCLHVPMCKEL--TTVSLLSFDHLEGVNRRQRIPRVKDMGVTEV-IPPGMSVEEWG----SRLKLALDKNSTSWLLLNLAALYWRHHGSTYQTINCLRSALYHSPWNHRDVALTSLGVVLHKANRT-LDALVLLHSSLEITQEVSKHCYVLGIMYSALKMFDMAEMCFRYVTTV 323 HSP 2 Score: 73.1738 bits (178), Expect = 5.199e-13 Identity = 55/193 (28.50%), Postives = 88/193 (45.60%), Query Frame = 1
Query: 1576 KGFDLDNLLTTKQQLTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGV--------NMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANL 2130
+G D+ + K+QL P PP C + + +D LE +K EK L + + Q + N R++D+G I A+++ S W+ N+A L+WRI+G+ A+A+ C RL++ S ++RDV LV+LA+IL R DA A K+ + H AN+
Sbjct: 696 RGVDISKHVDFKEQLK-----GFP-TPPLCRAKIRAGAWS----LDHLEGIKK--------------VEKQSLDPEIGMAQTLLAHDPHSPNKRIQDMGTHISRALEKDPTS-WVALNLASLFWRIIGDTAEAVQCLRLAISHSKDKHRDVALVSLASILFRAGYLADAKTTCLHALKVSPNSLVGHFTLANI 863 HSP 3 Score: 65.855 bits (159), Expect = 9.622e-11 Identity = 44/152 (28.95%), Postives = 74/152 (48.68%), Query Frame = 1
Query: 496 PFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEISLYK--IAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSL-DAIVLMKNAILISPHFTSHHMILGNI 942
P C + +HLE I+ PEI + + +A H +P + + + + + +W+ N+A+ +WR+ G A++CLR A+ S K++D+ALVSLA+I L + L DA +A+ +SP+ H L NI
Sbjct: 717 PLCRAKIRAG--AWSLDHLEGIKKVEKQSLDPEIGMAQTLLAHDPH-SPNKRIQDMGTHISRALEKDPTSWVALNLASLFWRIIGDTAEAVQCLRLAISHSKDKHRDVALVSLASI--LFRAGYLADAKTTCLHALKVSPNSLVGHFTLANI 863 HSP 4 Score: 63.5438 bits (153), Expect = 4.703e-10 Identity = 35/139 (25.18%), Postives = 74/139 (53.24%), Query Frame = 1
Query: 3148 SLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQ 3564
S+E+ G RL +++N+T W + ++ YWR G Q NCL A+ +SP H V L + +L++ N+ AL + H SL+ +Q +++ +++ ++ ++ A + + +++ A +K++QC++
Sbjct: 205 SVEEWGSRLKLALDKNSTSWLLLNLAALYWRHHGSTYQTINCLRSALYHSPWNHRDVALTSLGVVLHKANRTLDALVLLHSSLEI--TQEVSKHCYVLGIMYSALKMFDMAEMCFRYVTTVEPSASVAKKWLKAVQCEK 341 HSP 5 Score: 63.1586 bits (152), Expect = 6.716e-10 Identity = 31/88 (35.23%), Postives = 52/88 (59.09%), Query Frame = 1
Query: 1825 NMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKI 2088
M +E+ G R+ A+ + S W+L N+A LYWR G+ Q ++C R ++ SP +RDV L +L +L + R DA+ L+ ++ +I
Sbjct: 203 GMSVEEWGSRLKLALDKNSTS-WLLLNLAALYWRHHGSTYQTINCLRSALYHSPWNHRDVALTSLGVVLHKANRTLDALVLLHSSLEI 289 HSP 6 Score: 62.003 bits (149), Expect = 1.258e-9 Identity = 33/105 (31.43%), Postives = 56/105 (53.33%), Query Frame = 1
Query: 3151 LEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATME 3465
++D+G + +E++ T W ++ +WR+ GD +A CL LA+ +S + H V LV+ A+IL+R L A +L+ S N +V F +ANI +
Sbjct: 766 IQDMGTHISRALEKDPTSWVALNLASLFWRIIGDTAEAVQCLRLAISHSKDKHRDVALVSLASILFRAGYLADAKTTCLHALKV--SPNSLVGHFTLANILVAQD 868
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Nematostella
Match: EDO47888 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL92]) HSP 1 Score: 60.8474 bits (146), Expect = 2.635e-10 Identity = 51/174 (29.31%), Postives = 88/174 (50.57%), Query Frame = 1
Query: 541 FEHLETIRNRSMLEGVPEISLYKIAMPQHLTPTEYGHL--VASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTS---HHMILGNIYASLGQFNNSLHHYQLATSLYNPN--KDKIKLKDI 1041
++HLE I NR E P + ++AM E L + S+L Q + +S + +++N +WR++G+ H+IEC R AL SP D+ L++LA + + DAI L + ++ + P + H LG I + G+ + + H++ L NP+ +I L+DI
Sbjct: 12 YDHLEGIINR---ESHPPYAEPEVAMIFKKNEMEEVDLNVIESNLKQSFEESPNSVVVFNQIGNFWRIRGNTYHSIECFRKALENSP-NNADV-LLNLARVLFNLNYLQ-DAIYLTRRSLEMQPSDQNCWLQHFTLGEILKASGELDEAGTHFRNVLDL-NPSFHPAEIHLRDI 178 HSP 2 Score: 56.6102 bits (135), Expect = 8.036e-9 Identity = 31/109 (28.44%), Postives = 55/109 (50.46%), Query Frame = 1
Query: 3229 NYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQY-PDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSI 3552
N+WR+ G+ + C A+ENSP + +L+N A +L+ +N L+ A+ +T +SL+ P QN + F + I + ++A + L L F A ++ I
Sbjct: 72 NFWRIRGNTYHSIECFRKALENSP--NNADVLLNLARVLFNLNYLQDAIYLTRRSLEMQPSDQNCWLQHFTLGEILKASGELDEAGTHFRNVLDLNPSFHPAEIHLRDI 178
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Medaka
Match: ttc17 (tetratricopeptide repeat domain 17 [Source:NCBI gene;Acc:101161041]) HSP 1 Score: 152.14 bits (383), Expect = 8.115e-37 Identity = 107/366 (29.23%), Postives = 192/366 (52.46%), Query Frame = 1
Query: 85 LFLMGIIPPLPHINGYTHWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNA-LQQPFCESFFNQNFSMCCFEHLETIRNRSMLEG---VPEISLYKIAMPQHLTPT--EYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
LFL I + THW VT+ G I+ S +L+ P ++V ++QE + +++++E +L ++ N++ + + + + CV A L + L+ + LE K I DYL+ + +L L++P C F +S+ F+HL ++ RS L E ++ ++PQ+L + E H + +L + +S +W+LYNMA+FYWR+K + A +C+ ALH SP +++DIAL+++ANI H ++ AI+ L S FTSH+ LGNIYA LG++N+S+ Y+ A + + + R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 28 LFLFFCILIVDSGGATTHWVVTEDGKIQQQVDSPLNLKHPHDVVIFMRQETRVNYLKKLEKQLVAQKIHIEENEDRDTGLEQRHYKEDPDCVMAKVPLGDLDLYDGTFIPLETKDINPEDYLD----SQSALPPDLEKPDCAKLFELPYSIHAFQHLRGVQERSNLTSPILSKEDPIFS-SLPQNLGQSVDEVAHRIHQALLK----NSSSWVLYNMASFYWRMKNEPQRAADCVVRALHFSPRQHKDIALINMANILHRAHFSADAAILAHAALDLTSDLFTSHY-TLGNIYAMLGEYNHSVLCYEQAL------QAQPGFEQALRRKHAVLCQQKLEQRLEAQHRSLQRTLNELKEYQKQHDHY 377 HSP 2 Score: 113.62 bits (283), Expect = 5.826e-25 Identity = 66/215 (30.70%), Postives = 113/215 (52.56%), Query Frame = 1
Query: 409 LSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNF--SMCCFEHLETIRNRSMLEGVPEISLYKIAM---PQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
L++ AK I ++++ A LQ+P E N N SM +HL + NR+ + E L ++ +P + V + + + + +W+L +MAA YWRVKG K AI+CLR AL+ +P +D+ L+SLAN+F + DA+ + + A+ I+PHF +H L N+Y ++ +F ++H Y+ L + P KD+++
Sbjct: 986 LAVSAKNIDITEHIDFA-------TPLQEPAVEPLCNANLAASMHTLDHLAGVANRAAIHYTGESQLREVLQNLGKDKFSPQSFEQ-VGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALNHAPHHMKDVPLISLANVFQNARLWE-DALTVARMAVEIAPHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFAPAKDRLR 1191 HSP 3 Score: 97.0561 bits (240), Expect = 7.937e-20 Identity = 59/235 (25.11%), Postives = 113/235 (48.09%), Query Frame = 1
Query: 2863 APEDCEHVAPFDFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTPKGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYS---LEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQC 3558
PE+C+ D T +++++ I++ +D TP L P C + +D + E L D++S E +G R+ +E+N T W +++++ YWRV G ++A +CL A+ ++P + V L++ AN+ E AL + +++ + +++V F +AN++ ME++ KA +YE+ L L+ +F A R+++IQC
Sbjct: 966 GPEECQRTRRVDLTTVASTWLAVSAKNIDITEHIDFATP--LQEPAVEPLCNANLAASM-HTLDHLAGVANRAAIHYTGESQLREVLQNLGKDKFSPQSFEQVGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALNHAPHHMKDVPLISLANVFQNARLWEDALTVARMAVEI--APHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFAPAKDRLRTIQC 1195 HSP 4 Score: 78.5666 bits (192), Expect = 3.911e-14 Identity = 67/249 (26.91%), Postives = 115/249 (46.18%), Query Frame = 1
Query: 2896 DFKTYTPLYVSLNTMRINVVSLLDS---LTP-------GYLF----SFH--QHPYCTPKGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
D Y ++ L T IN LDS L P LF S H QH + +N I+ K E +S +P+ NL S ++++ R++ + +N++ W + ++ YWR+ + Q+A +C+ A+ SP H+ + L+N ANIL+R + +A + + + + NI+A + ++N + L YE L + FE+A+ R ++ CQQ + Q LE QH
Sbjct: 127 DLDLYDGTFIPLETKDINPEDYLDSQSALPPDLEKPDCAKLFELPYSIHAFQHLRGVQERSNLTSPILSK-----EDPIFSSLPQ-NLGQS----------VDEVAHRIHQALLKNSSSWVLYNMASFYWRMKNEPQRAADCVVRALHFSPRQHKDIALINMANILHRAHF--SADAAILAHAALDLTSDLFTSHYTLGNIYAMLGEYNHSVLCYEQALQAQPGFEQALRRKHAVLCQQKLEQRLEAQH 357 HSP 5 Score: 68.5514 bits (166), Expect = 3.903e-11 Identity = 55/209 (26.32%), Postives = 91/209 (43.54%), Query Frame = 1
Query: 1618 LTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKL 2244
+T H + + P P N + +D L + + I Y G S E +LQ L K + E +G RI +++ ++W+L ++A LYWR+ G +A+DC R ++ +P +DVPL++LA + + +DA+ + A +I H AN+Y E A H E + L I+C L
Sbjct: 995 ITEHIDFATPLQEPAVEPLCNANLAASMHTLDHLAGVANRAAIHY--TGESQLRE--VLQNLGK-DKFSPQSFEQVGTRIAKVLEKN-QTSWVLSSMAALYWRVKGQGKKAIDCLRQALNHAPHHMKDVPLISLANVFQNARLWEDALTVARMAVEIAPHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFAPAKDRLRTIQCYL 1197 HSP 6 Score: 64.6994 bits (156), Expect = 6.833e-10 Identity = 44/148 (29.73%), Postives = 75/148 (50.68%), Query Frame = 1
Query: 1816 QGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPET--HILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKLCRS 2253
+G L+ IG I A+K + W + N A L+WR GN ++AL C R + +P + +PL N A +L+ + A L+E A ++ SEP T +++ +L ++N LA L +L+ +TL ++ C+ CR+
Sbjct: 596 RGGGQTLDKIGTIIAEAMKHATVPLWQIRNEAALFWRAKGNSSRALQCLRQVLSSAPPSHHHLPLSNAANLLLHYGLTNHAQTLLERASVLNASEPHTLLGLVSVHLAQNNATGALA---LFRRVLE-TTLTSSSAFSSFAGCQQCRT 739 HSP 7 Score: 56.9954 bits (136), Expect = 1.322e-7 Identity = 38/138 (27.54%), Postives = 69/138 (50.00%), Query Frame = 1
Query: 1687 DLTPLDLIDSLESLKSD--------------NLISYQN----KGRSNFAEKHLLQE---LLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIR 2037
D+ P D +DS +L D ++ ++Q+ + RSN L +E L Q + ++++ RI A+ + S+W+L+N+A YWR+ +A DC ++ SP +++D+ L+N+A IL R
Sbjct: 142 DINPEDYLDSQSALPPDLEKPDCAKLFELPYSIHAFQHLRGVQERSNLTSPILSKEDPIFSSLPQNLGQSVDEVAHRIHQALLKN-SSSWVLYNMASFYWRMKNEPQRAADCVVRALHFSPRQHKDIALINMANILHR 278
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Medaka
Match: ttc17 (tetratricopeptide repeat domain 17 [Source:NCBI gene;Acc:101161041]) HSP 1 Score: 152.14 bits (383), Expect = 8.361e-37 Identity = 106/365 (29.04%), Postives = 190/365 (52.05%), Query Frame = 1
Query: 85 LFLMGIIPPLPHINGYTHWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEG---VPEISLYKIAMPQHLTPT--EYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRY 1164
LFL I + THW VT+ G I+ S +L+ P ++V ++QE + +++++E +L ++ N++ + + + + CV A L + L+ + LE K I DYL+ + L++P C F +S+ F+HL ++ RS L E ++ ++PQ+L + E H + +L + +S +W+LYNMA+FYWR+K + A +C+ ALH SP +++DIAL+++ANI H ++ AI+ L S FTSH+ LGNIYA LG++N+S+ Y+ A + + + R + C +L +++Q + + + L+EL+ +Q + + Y
Sbjct: 28 LFLFFCILIVDSGGATTHWVVTEDGKIQQQVDSPLNLKHPHDVVIFMRQETRVNYLKKLEKQLVAQKIHIEENEDRDTGLEQRHYKEDPDCVMAKVPLGDLDLYDGTFIPLETKDINPEDYLDS---QSALPPDLEKPDCAKLFELPYSIHAFQHLRGVQERSNLTSPILSKEDPIFS-SLPQNLGQSVDEVAHRIHQALLK----NSSSWVLYNMASFYWRMKNEPQRAADCVVRALHFSPRQHKDIALINMANILHRAHFSADAAILAHAALDLTSDLFTSHY-TLGNIYAMLGEYNHSVLCYEQAL------QAQPGFEQALRRKHAVLCQQKLEQRLEAQHRSLQRTLNELKEYQKQHDHY 377 HSP 2 Score: 113.62 bits (283), Expect = 6.403e-25 Identity = 66/215 (30.70%), Postives = 113/215 (52.56%), Query Frame = 1
Query: 409 LSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNF--SMCCFEHLETIRNRSMLEGVPEISLYKIAM---PQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSL---YNPNKDKIK 1029
L++ AK I ++++ A LQ+P E N N SM +HL + NR+ + E L ++ +P + V + + + + +W+L +MAA YWRVKG K AI+CLR AL+ +P +D+ L+SLAN+F + DA+ + + A+ I+PHF +H L N+Y ++ +F ++H Y+ L + P KD+++
Sbjct: 883 LAVSAKNIDITEHIDFA-------TPLQEPAVEPLCNANLAASMHTLDHLAGVANRAAIHYTGESQLREVLQNLGKDKFSPQSFEQ-VGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALNHAPHHMKDVPLISLANVFQNARLWE-DALTVARMAVEIAPHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFAPAKDRLR 1088 HSP 3 Score: 97.4413 bits (241), Expect = 5.462e-20 Identity = 59/235 (25.11%), Postives = 113/235 (48.09%), Query Frame = 1
Query: 2863 APEDCEHVAPFDFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTPKGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYS---LEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQC 3558
PE+C+ D T +++++ I++ +D TP L P C + +D + E L D++S E +G R+ +E+N T W +++++ YWRV G ++A +CL A+ ++P + V L++ AN+ E AL + +++ + +++V F +AN++ ME++ KA +YE+ L L+ +F A R+++IQC
Sbjct: 863 GPEECQRTRRVDLTTVASTWLAVSAKNIDITEHIDFATP--LQEPAVEPLCNANLAASM-HTLDHLAGVANRAAIHYTGESQLREVLQNLGKDKFSPQSFEQVGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALNHAPHHMKDVPLISLANVFQNARLWEDALTVARMAVEI--APHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFAPAKDRLRTIQC 1092 HSP 4 Score: 78.9518 bits (193), Expect = 3.001e-14 Identity = 67/249 (26.91%), Postives = 115/249 (46.18%), Query Frame = 1
Query: 2896 DFKTYTPLYVSLNTMRINVVSLLDS---LTP-------GYLF----SFH--QHPYCTPKGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLE-QH 3591
D Y ++ L T IN LDS L P LF S H QH + +N I+ K E +S +P+ NL S ++++ R++ + +N++ W + ++ YWR+ + Q+A +C+ A+ SP H+ + L+N ANIL+R + +A + + + + NI+A + ++N + L YE L + FE+A+ R ++ CQQ + Q LE QH
Sbjct: 127 DLDLYDGTFIPLETKDINPEDYLDSQSALPPDLEKPDCAKLFELPYSIHAFQHLRGVQERSNLTSPILSK-----EDPIFSSLPQ-NLGQS----------VDEVAHRIHQALLKNSSSWVLYNMASFYWRMKNEPQRAADCVVRALHFSPRQHKDIALINMANILHRAHF--SADAAILAHAALDLTSDLFTSHYTLGNIYAMLGEYNHSVLCYEQALQAQPGFEQALRRKHAVLCQQKLEQRLEAQH 357 HSP 5 Score: 68.9366 bits (167), Expect = 3.311e-11 Identity = 55/209 (26.32%), Postives = 91/209 (43.54%), Query Frame = 1
Query: 1618 LTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKL 2244
+T H + + P P N + +D L + + I Y G S E +LQ L K + E +G RI +++ ++W+L ++A LYWR+ G +A+DC R ++ +P +DVPL++LA + + +DA+ + A +I H AN+Y E A H E + L I+C L
Sbjct: 892 ITEHIDFATPLQEPAVEPLCNANLAASMHTLDHLAGVANRAAIHY--TGESQLRE--VLQNLGK-DKFSPQSFEQVGTRIAKVLEKN-QTSWVLSSMAALYWRVKGQGKKAIDCLRQALNHAPHHMKDVPLISLANVFQNARLWEDALTVARMAVEIAPHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFAPAKDRLRTIQCYL 1094 HSP 6 Score: 64.3142 bits (155), Expect = 8.225e-10 Identity = 44/148 (29.73%), Postives = 75/148 (50.68%), Query Frame = 1
Query: 1816 QGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPET--HILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKLCRS 2253
+G L+ IG I A+K + W + N A L+WR GN ++AL C R + +P + +PL N A +L+ + A L+E A ++ SEP T +++ +L ++N LA L +L+ +TL ++ C+ CR+
Sbjct: 533 RGGGQTLDKIGTIIAEAMKHATVPLWQIRNEAALFWRAKGNSSRALQCLRQVLSSAPPSHHHLPLSNAANLLLHYGLTNHAQTLLERASVLNASEPHTLLGLVSVHLAQNNATGALA---LFRRVLE-TTLTSSSAFSSFAGCQQCRT 676 HSP 7 Score: 56.9954 bits (136), Expect = 1.507e-7 Identity = 38/138 (27.54%), Postives = 69/138 (50.00%), Query Frame = 1
Query: 1687 DLTPLDLIDSLESLKSD--------------NLISYQN----KGRSNFAEKHLLQE---LLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIR 2037
D+ P D +DS +L D ++ ++Q+ + RSN L +E L Q + ++++ RI A+ + S+W+L+N+A YWR+ +A DC ++ SP +++D+ L+N+A IL R
Sbjct: 142 DINPEDYLDSQSALPPDLEKPDCAKLFELPYSIHAFQHLRGVQERSNLTSPILSKEDPIFSSLPQNLGQSVDEVAHRIHQALLKN-SSSWVLYNMASFYWRMKNEPQRAADCVVRALHFSPRQHKDIALINMANILHR 278
BLAST of Tetratricopeptide repeat domain 17 vs. Planmine SMEST
Match: SMESG000036512.1 (SMESG000036512.1) HSP 1 Score: 2412.11 bits (6250), Expect = 0.000e+0 Identity = 1175/1182 (99.41%), Postives = 1180/1182 (99.83%), Query Frame = 1
Query: 46 MKFLFPYSYIYVILFLMGIIPPLPHINGYTHWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKNLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHILSLEAKGIKTNDYLNEAILTNISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEISLYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRYQDIKISLIHEIENNATQERNQIIYKTLGKLKPHQLVQCVISDLLTKEESVCELSTESLITHIFKDLNRSPSESNRQEFQSDKELFRPTRSRVYKTLRLEQYKPSEYVHNINETSCKRLNCPRNYDXXXXXXXXXXXXKGFDLDNLLTTKQQLTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKLCRSYNSSDSHSDVVNKNFEMRENITQIFINYKMCSSTSECRHIVSENYLFLPHIKIAIKGPTFSPADIEKITRVEFDSIHQETANVMYGMLWNTNLSNLHIQDHDCLLTNDSARSVGCHRNEEIYAASQNAFNFLAELRAVLKSISTQNMNNLTAKPLSVNKHLCHNDPSKSTSKDDTNQSRSERTNDIQETIINLISSRVVINPLAPEDCEHVAPFDFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTPKGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLEQH 3591
MKFLFPYSYIYVILFLMGIIPPLPHINGYTHWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEK+LEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHI+SLEAKGIKTNDYLNEAIL NISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEISLYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRYQDIKISLIHEIENNATQERNQIIYKTLGKLKP+QLVQCVISDLLTKEESVCELSTESLITHIFKDLNRSPSESNRQEFQSDK+LFRPTRSRVYKTLRLEQYKPSEYVHNINETSCKRLNCPRNYDSLLLSLYISPSSKGFDLDNLLTTKQQLTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKLCRSYNSSDSHSDVVNK FEMRENITQIFINYKMCSSTSECRHIVSENYLFLPHIKIAIKGPTFSPADIEKITRVEFDSIHQETANVMYGMLWNTNLSNLHIQDHDCLLTNDSARSVGCHRNEEIYAASQNAFNFLAELRAVLKSISTQNMNNLTAKPLSVNKHLCHNDPSKSTSKDDTNQSRSERTNDIQETIINLISSRVVINPLAPEDCEHVAPFDFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTPKGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEA+YRIKSIQCQQMVMQNLEQH
Sbjct: 1 MKFLFPYSYIYVILFLMGIIPPLPHINGYTHWTVTQHGMIEPLTISYYHLRQPWNLVKLIQQEKHLEFIQRIELKLNQVSNDLQANQEYQNKVHKYYVDSESACVKASKLLSEFTLHSNHIMSLEAKGIKTNDYLNEAILINISLNALQQPFCESFFNQNFSMCCFEHLETIRNRSMLEGVPEISLYKIAMPQHLTPTEYGHLVASSLGQHYNDSSKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISPHFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAKCSLELSVAIDSQQKKIDKQLDELELFQIETNRYQDIKISLIHEIENNATQERNQIIYKTLGKLKPYQLVQCVISDLLTKEESVCELSTESLITHIFKDLNRSPSESNRQEFQSDKDLFRPTRSRVYKTLRLEQYKPSEYVHNINETSCKRLNCPRNYDSLLLSLYISPSSKGFDLDNLLTTKQQLTVHHEHSLPWYPPHCSEYVNITDLTPLDLIDSLESLKSDNLISYQNKGRSNFAEKHLLQELLKLVQGVNMRLEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFKIDYSEPETHILAANLYRDNNELMLAYHHLEIAILQNSTLKVNNVDLDAIKCKLCRSYNSSDSHSDVVNKKFEMRENITQIFINYKMCSSTSECRHIVSENYLFLPHIKIAIKGPTFSPADIEKITRVEFDSIHQETANVMYGMLWNTNLSNLHIQDHDCLLTNDSARSVGCHRNEEIYAASQNAFNFLAELRAVLKSISTQNMNNLTAKPLSVNKHLCHNDPSKSTSKDDTNQSRSERTNDIQETIINLISSRVVINPLAPEDCEHVAPFDFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTPKGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAIYRIKSIQCQQMVMQNLEQH 1182
BLAST of Tetratricopeptide repeat domain 17 vs. Planmine SMEST
Match: SMESG000036512.1 (SMESG000036512.1) HSP 1 Score: 873.618 bits (2256), Expect = 0.000e+0 Identity = 416/417 (99.76%), Postives = 417/417 (100.00%), Query Frame = 1
Query: 2341 MCSSTSECRHIVSENYLFLPHIKIAIKGPTFSPADIEKITRVEFDSIHQETANVMYGMLWNTNLSNLHIQDHDCLLTNDSARSVGCHRNEEIYAASQNAFNFLAELRAVLKSISTQNMNNLTAKPLSVNKHLCHNDPSKSTSKDDTNQSRSERTNDIQETIINLISSRVVINPLAPEDCEHVAPFDFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTPKGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAVYRIKSIQCQQMVMQNLEQH 3591
MCSSTSECRHIVSENYLFLPHIKIAIKGPTFSPADIEKITRVEFDSIHQETANVMYGMLWNTNLSNLHIQDHDCLLTNDSARSVGCHRNEEIYAASQNAFNFLAELRAVLKSISTQNMNNLTAKPLSVNKHLCHNDPSKSTSKDDTNQSRSERTNDIQETIINLISSRVVINPLAPEDCEHVAPFDFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTPKGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEA+YRIKSIQCQQMVMQNLEQH
Sbjct: 1 MCSSTSECRHIVSENYLFLPHIKIAIKGPTFSPADIEKITRVEFDSIHQETANVMYGMLWNTNLSNLHIQDHDCLLTNDSARSVGCHRNEEIYAASQNAFNFLAELRAVLKSISTQNMNNLTAKPLSVNKHLCHNDPSKSTSKDDTNQSRSERTNDIQETIINLISSRVVINPLAPEDCEHVAPFDFKTYTPLYVSLNTMRINVVSLLDSLTPGYLFSFHQHPYCTPKGTNFLRQIVDKYKIDIETSQYSKIPEYNLHTSFLKTFDDRYSLEDIGKRLYTGIEQNATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLKADFEEAIYRIKSIQCQQMVMQNLEQH 417 HSP 2 Score: 58.9214 bits (141), Expect = 1.372e-8 Identity = 29/84 (34.52%), Postives = 51/84 (60.71%), Query Frame = 1
Query: 1834 LEDIGQRIVTAIKRRLMSNWILFNIAGLYWRIVGNVAQALDCQRLSVKLSPIEYRDVPLVNLAAILIRFQRNQDAMKLIETAFK 2085
LEDIG+R+ T I++ ++W + I+ YWR+ G+ QA +C L+++ SP + V LVN A IL R + + A+++ + +
Sbjct: 271 LEDIGKRLYTGIEQN-ATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRINKLEAALEITHKSLQ 353 HSP 3 Score: 53.1434 bits (126), Expect = 9.168e-7 Identity = 36/128 (28.12%), Postives = 63/128 (49.22%), Query Frame = 1
Query: 691 SKNWILYNMAAFYWRVKGSAKHAIECLRAALHTSPWKYQDIALVSLANIFHLIKTTSLDAIVLMKNAILISP---HFTSHHMILGNIYASLGQFNNSLHHYQLATSLYNPNKDKIKLKDIEERIFSAK 1065
+ +W + ++ YWRV G A+ A CL A+ SP ++ + LV+ ANI + I L+A + + + L P ++ ++ NI+A++ Q+N + Y+ SL D EE I+ K
Sbjct: 286 ATDWKVATISVNYWRVTGDAQQAFNCLELAMENSPEFHEKVILVNAANILYRIN--KLEAALEITHKSLQYPDSQNWIVIPFLVANIFATMEQWNKATLFYEACLSLK---------ADFEEAIYRIK 402 The following BLAST results are available for this feature:
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 3
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 1
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 4
BLAST of Tetratricopeptide repeat domain 17 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of Tetratricopeptide repeat domain 17 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Tetratricopeptide repeat domain 17 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 2
BLAST of Tetratricopeptide repeat domain 17 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002880 ID=SMED30002880|Name=Tetratricopeptide repeat domain 17|organism=Schmidtea mediterranea sexual|type=transcript|length=3641bpback to top protein sequence of SMED30002880-orf-1 >SMED30002880-orf-1 ID=SMED30002880-orf-1|Name=SMED30002880-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1183bp MKFLFPYSYIYVILFLMGIIPPLPHINGYTHWTVTQHGMIEPLTISYYHLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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