Degenerin unc-8

Overview
NameDegenerin unc-8
Smed IDSMED30002847
Length (bp)1604
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Degenerin unc-8 (SMED30002847) t-SNE clustered cells

Violin plots show distribution of expression levels for Degenerin unc-8 (SMED30002847) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Degenerin unc-8 (SMED30002847) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Degenerin unc-8 (SMED30002847) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30002847

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30002847h1SMcG0013132 dd_Smed_v4_16557_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30002847h1SMcG0013132 dd_Smed_v4_16557_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30002847h1SMcG0013132 dd_Smed_v4_16557_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Degenerin unc-8 vs. TrEMBL
Match: S5W2R2 (Asic OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 494.197 bits (1271), Expect = 7.824e-168
Identity = 256/496 (51.61%), Postives = 355/496 (71.57%), Query Frame = 1 
Query:    1 MIEILQSSTIHGVSHIHGAKSQITKVLWXXXXXXXXXXXXXXXXXXXXKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIINGKRNTDYELEERTIAMSSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNIPCFTFHIDKSKFLNQNQIKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGVQRKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLPIYKNETGPPRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLKCQDYRFIKCNEVKYKIEKDKELFVEFWSGLTNQRRNELLKKVSYYLMEKFDIK-NYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELMY 1485
            MI+++QSSTIHG+ HI  A ++I KVLW  LF+ G+I I VNIVF+ +K+ SNPV+IS+  +HEPFIWPD+TFC PT PY F  NSQ Y HW     +T+R+  ++A +T + ++I+ +R  DYELEERTIAMSSADP KL+   F+ ++  I + K  +G+Y+  +    + T   ED K LFT+ +VQ+RNNIPC TFH+DKS+ + Q  IKS+ F  K N ESY +FNSSY  +S+FLYI+N++ IP  NEI+L PG+NN+V L+Q+R+ Y G++R CRN+ FE ELYD LLQST  + G YDDCKK+ SQ+ +V  C CY+ FLPI+KN +G PR+CLNA+ +SE E+++NAKCM + + K+      R  +  +C+ YR I CN+V YKI+  KE+ V+ WS  TN RR E++K +     +  +   ++ E+++DN + + INR+ + GDLYKEE EYPFSELLSD+GGLMGLWLG+SV+GLFEI E +Y
Sbjct:    1 MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQS-SSTKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFVY 495
[Close]
BLAST of Degenerin unc-8 vs. TrEMBL
Match: A0A183A5V1 (Uncharacterized protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS2336 PE=3 SV=1)

HSP 1 Score: 266.159 bits (679), Expect = 9.024e-77
Identity = 170/520 (32.69%), Postives = 278/520 (53.46%), Query Frame = 1 
Query:   10 ILQSSTIHGVSHIHGAKSQITKVLWXXXXXXXXXXXXXXXXXXXXKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIINGKRNTDYELEERTIAMSSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKP---LFTAPLVQIRNNIPCFTFHI----DKSKFLNQNQIKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGVQRKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLPIYKNET-----GPPRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLK-CQDYRFIK-CNEVKYKIEK-DKELFVEFWSGLTNQRRNELL--------------KKVSYYLMEKFDIKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELM 1482
            +L+ ST+HG+SH+  A S+I + +W+ L++ G+ G F N+ F++ +Y + PVL S+K DHE FIWPD+T C P APY     ++    W+ +  R  R+ + ++ +  +F  I+       E+  + +  S+  P +    + +  I  +  +K + GI+  ++      ++F +   P    F A ++Q R+NIPC+T  +     +   L+ NQ+   S  LKFN +S+L+ NSSY  R++ L+I+     P    + L  G+ + VS+S +R+     +  CR   F  +++D  L++     G  D C K+ SQ+L++  C CYSPFLP    +      G P +C N + ++   I +NAKCM DVYT++  +  + N    + C+ +R    C    Y  E   +   +E WS   N+ R   L              +++   L    +  N F  MR+NF  +TI+R+F +G L  EE EYP SELLSD+GGLMGLW+G+SV+GLFE+ EL+
Sbjct:   33 LLEHSTVHGLSHVSTASSRIGRSIWLILWLAGVAGFFTNLSFIVSRYMTRPVLTSYKHDHESFIWPDITLCNPMAPYPVHLRNRT-EKWNELRLRATRVAKNISED--LFAAIDDAEQ--LEIAIQALLYSTISPEQFGVGEPQELIQFVAADKGRSGIHLTVE----MYSTFTDLDAPKTQYFHAQMLQKRHNIPCYTLQLAHVLSQEDCLSTNQV---SLGLKFNHDSFLIINSSYAPRNIDLFISLPGHFPEDESMELLSGYTHKVSVSMTRFIREPNRLPCRTDEFVAQMFDANLKTRREIVGSADFCHKLVSQRLYINNCGCYSPFLPYPVVDEHLLVHGQPVLCFNMSHFNITSIDQNAKCMYDVYTQYHDHSVYMNLPEAQYCETFRSTPPCESTSYMPESLRRTPIIELWSDTINEGRTAFLTSTFESVFGPDLPEERIRQLLNNSGNNSNMFTYMRNNFGMVTISRKFPRGTLTHEELEYPLSELLSDLGGLMGLWIGISVIGLFEVVELL 540
[Close]
BLAST of Degenerin unc-8 vs. TrEMBL
Match: A0A4E0RSD9 (Degenerin unc-8 OS=Fasciola hepatica OX=6192 GN=D915_000009 PE=3 SV=1)

HSP 1 Score: 255.758 bits (652), Expect = 8.797e-73
Identity = 169/521 (32.44%), Postives = 277/521 (53.17%), Query Frame = 1 
Query:   10 ILQSSTIHGVSHIHGAKSQITKVLWXXXXXXXXXXXXXXXXXXXXKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIING---KRNTDYELEERTIAM---SSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNIPCFTFHIDKSKFLNQNQ---IKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGVQRKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLP-IYKNETGP----PRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLK-CQDYRFI-KCNEVKYKIEKDKEL-FVEFWSGLTNQRRNELL--------------KKVSYYLMEKFDIKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFEL 1479
            +L+ ST+HG+SH+  A ++I + +W+ L++ G+ G F N+ F++ +Y + PVL S+K DHE FIWPD+T C P APY    N+++   W+        ++ +LA  T V + I+G       + E EE T+     S+  P +   ND    +  +  +K Q GI+  I+      T+        F   ++Q R NIPC+T  +D+   LN+ +    K +S  LKFN +S L+ NSSY   ++ L+I+    +P    + +  G+++ V+++  R+     +  CR + F T+++D  L++     G  D C K+ SQ+L++  C CYSPFLP     +  P    P +C N + ++   I RNA+CM DVYT+F+    + N      C+ +R    C  + Y +E  +    +EFW+   N+ R+  +              +++   +    +  +    MR+NF  + I R+  +G L  EE EYP SELLSD+GGLMGLW+G+SV+GLFE+ EL
Sbjct:   34 LLEHSTVHGLSHVSTAGTRIGRSVWLILWMAGVAGFFTNLSFIVSRYMTRPVLTSYKHDHELFIWPDITLCNPMAPYPVHLNNRS-EKWN--------LLHQLA--TAVSRNISGNLFATIDEAEQEEVTVQALIHSTVSPMEFGANDPHELVHFVAVDKGQTGIHLTIEMDA-TFTNLDIPKHRYFHVQVLQKRYNIPCYTLRLDQ--VLNEEECASTKQVSLGLKFNHDSNLIINSSYAPFNIDLFISLPGHMPEDEPMEILSGYSHKVTVTMGRFTRERTRLPCRTEQFVTQVFDADLKTQREVVGSADFCLKLLSQRLYIDHCGCYSPFLPYPVMGQDHPLYQQPVLCFNMSHFNASGIDRNARCMYDVYTQFKEDFVYMNLPEAGYCETFRATPPCESINYVLESPRRTPIIEFWADTVNEARSAFVTSTFESVFGQDLPEERLKQMVNNSGNTSSLLFYMRNNFGLVKITRKLPRGTLTHEELEYPLSELLSDVGGLMGLWVGISVIGLFEVVEL 540
[Close]
BLAST of Degenerin unc-8 vs. TrEMBL
Match: A0A504YRR8 (Degenerin unc-8 OS=Fasciola gigantica OX=46835 GN=FGIG_05554 PE=3 SV=1)

HSP 1 Score: 253.832 bits (647), Expect = 5.982e-72
Identity = 168/521 (32.25%), Postives = 277/521 (53.17%), Query Frame = 1 
Query:   10 ILQSSTIHGVSHIHGAKSQITKVLWXXXXXXXXXXXXXXXXXXXXKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIING---KRNTDYELEERTIAM---SSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNIPCFTFHIDKSKFLNQNQ---IKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGVQRKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLP-IYKNETGP----PRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLK-CQDYRFI-KCNEVKYKIEKDKEL-FVEFWSGLTNQRRNELL--------------KKVSYYLMEKFDIKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFEL 1479
            +L+ ST+HG+SH+  A ++I + +W+ L++ G+ G F N+ F++ +Y + PVL S+K DHE FIWPD+T C P APY    N+++   W+        ++ +LA  T V + I+G       + E EE T+     S+  P +   ND    +  +  +K Q GI+  I+      T+        F   ++Q R NIPC+T  +D+   LN+ +    K +S  LKFN +S L+ NSSY   ++ L+I+    +P    + +  G+++ V+++  R+     +  CR + F T+++D  L++     G  D C K+ SQ+L++  C CYSPFLP     +  P    P +C N + ++   I RNA+CM +VYT+F+    + N      C+ +R    C  + Y +E  +    +EFW+   N+ R+  +              +++   +    +  +    MR+NF  + I R+  +G L  EE EYP SELLSD+GGLMGLW+G+SV+GLFE+ EL
Sbjct:   34 LLEHSTVHGLSHVSTASTRIGRSVWLILWMAGVAGFFTNLSFIVSRYMTRPVLTSYKHDHELFIWPDITLCNPMAPYPVHLNNRS-EKWN--------LLHQLA--TAVSRNISGNLFATIDEAEQEEVTVQALIHSTVSPMEFGANDPHELVHFVAVDKGQTGIHLTIEMDA-TFTNLDIPKHRYFHVQVLQKRYNIPCYTLRLDQ--VLNEEECASTKQVSLGLKFNHDSNLIINSSYAPFNIDLFISLPGHMPEDEPMEILSGYSHKVTVTMGRFTRERTRLPCRTEQFVTQVFDADLKTQREVVGSADFCLKLLSQRLYIDHCGCYSPFLPYPVMGQDHPLYQHPVLCFNMSHFNASGIDRNARCMYEVYTQFKEDFIYMNLPEAGFCETFRATPPCESINYVLESPRRTPIIEFWADTVNEARSAFVTSTFESVFGQDLPEERLKQMVNNSGNTSSLLFYMRNNFGLVKITRKLPRGTLTHEELEYPLSELLSDVGGLMGLWVGISVIGLFEVVEL 540
[Close]
BLAST of Degenerin unc-8 vs. TrEMBL
Match: A0A5J4NUF1 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0013022 PE=3 SV=1)

HSP 1 Score: 251.521 bits (641), Expect = 2.045e-71
Identity = 164/521 (31.48%), Postives = 270/521 (51.82%), Query Frame = 1 
Query:   10 ILQSSTIHGVSHIHGAKSQITKVLWXXXXXXXXXXXXXXXXXXXXKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIINGKRNTDYELEERTIAMSSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNIPCFTFHIDKS-KFLNQNQIKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGVQRKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLP---IYKNE--TGPPRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLK-CQDYRFIKCNEVKYKIEK-DKELFVEFWSGLTNQRRNELLKK---------------VSYYLMEKFD--------IKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFEL 1479
            +L+ ST+HG+SH+  A +++ ++ W  L + GI G F N+ F+I +Y + PVL S+  ++E FIWPD+T C   APY    + +    W  +  +     ++L   + +F  I+ +     E+  + +  S+  P +    +    I  +  +   +GI   ++ SG  +T     LK  F   ++Q R N+PC+T  +  S   +  NQ+ SI   +KFN+ESY + NSSY    + L+I++    PH + I + PG+   +SL  SR      +  CR   + TE++D  L +     G    C ++ SQ L++  C CYSPFLP   +Y ++  +    +C N + +S  +I RNA CM  +Y ++Q    + +    + C+ +R   C++V+YK+    +   VE WS   N+ R   L                 VS+   +  D        +    + MRDNF  +++NR+ + G+L +EE EYP SEL+SD+GGLMGLW+G+SV+GLFEI EL
Sbjct:   30 LLEHSTVHGLSHVSTAATKLGRITWFCLLLAGIAGFFTNLSFIIDRYLTRPVLTSYISEYEGFIWPDITLCNAMAPYSLHLHGR-IPKWQALRNQASAFAQKL--NSSLFASIDSQDQN--EIAIQALMYSTLSPPEYGVGEPEEFIQFVATDVGYQGIILTVEISG-NMTHLNPPLKKYFHTQVLQKRYNVPCYTLQLRHSLTAVQSNQVNSIGLGVKFNVESYRIINSSYASPYIDLFISHPGHAPHDDPIEMLPGYTLSLSLRMSRLRREPARLSCRTDFYTTEVFDPDLVTKRRVNGSATFCHRIVSQHLYLNSCHCYSPFLPYPVVYNHKLFSKMAILCFNMSRFSVAQINRNADCMLRIYERYQLSSVYNSVPEARACEQFRKPLCDDVEYKLSDIRRTAMVELWSNSYNEARIAFLTSSFQNLFSSDIPPEQLVSWLDSDTKDDNTKDNDSMPKILKYMRDNFGLLSVNRKSELGELVREELEYPLSELMSDVGGLMGLWIGISVIGLFEIVEL 544
[Close]
BLAST of Degenerin unc-8 vs. Ensembl Nematostella
Match: EDO42137 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2F2])

HSP 1 Score: 50.447 bits (119), Expect = 1.254e-6
Identity = 22/52 (42.31%), Postives = 33/52 (63.46%), Query Frame = 1 
Query: 1366 LYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELMYLYLKNLCYQTSK 1521
            L +E   Y F  LLSDIGG MG+W+G+S +   E+ EL+ + L N+  ++ K
Sbjct:  447 LVQETLAYTFMSLLSDIGGQMGMWIGISALTCAELIELVCVILANMSNRSKK 498
[Close]
BLAST of Degenerin unc-8 vs. Ensembl Nematostella
Match: EDO39446 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SA83])

HSP 1 Score: 48.1358 bits (113), Expect = 6.675e-6
Identity = 29/115 (25.22%), Postives = 56/115 (48.70%), Query Frame = 1 
Query: 1156 IKCNEVKYKIEKDKELFVE--FWSGLTNQRRNELLKKVSYYLMEKFDIKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELMYLYL 1494
            ++C+ V++ ++     +    FW  ++N+R   +            D K + E  R   I + +  +    ++ KE+  Y  S+L  D GG MGL+LG S++ + E  +L+ +YL
Sbjct:  341 VRCSRVEFDVQLSSLYYPPDNFWETISNERSLTIYAN---------DTKKFQEWYRRRVIQLNVFYKELTTEVRKEKEAYTISDLAGDFGGNMGLFLGCSILTIAEFIDLLVVYL 446
[Close]
BLAST of Degenerin unc-8 vs. Ensembl Medaka
Match: asic1a (acid-sensing ion channel 1 [Source:NCBI gene;Acc:101159102])

HSP 1 Score: 48.9062 bits (115), Expect = 9.471e-6
Identity = 29/97 (29.90%), Postives = 56/97 (57.73%), Query Frame = 1 
Query: 1255 KKVSYYLMEKFDIKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELMYLYLK-NLCYQTSKQQSNMEK 1542
            K  + YL +K++    +  ++DN + + I  E    +  +++  Y  + LL DIGG MGL++G S++ + EIF+ +Y  +K  LC  + K+ +N ++
Sbjct:  382 KASAKYLAKKYNKSEQY--IKDNILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTILEIFDYLYEVIKYKLCRCSDKKHNNTDQ 476
[Close]
BLAST of Degenerin unc-8 vs. Planmine SMEST
Match: SMESG000017678.1 (SMESG000017678.1)

HSP 1 Score: 1032.71 bits (2669), Expect = 0.000e+0
Identity = 520/521 (99.81%), Postives = 520/521 (99.81%), Query Frame = 1 
Query:    1 MIEILQSSTIHGVSHIHGAKSQITKVLWXXXXXXXXXXXXXXXXXXXXKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIINGKRNTDYELEERTIAMSSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNIPCFTFHIDKSKFLNQNQIKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGVQRKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLPIYKNETGPPRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLKCQDYRFIKCNEVKYKIEKDKELFVEFWSGLTNQRRNELLKKVSYYLMEKFDIKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELMYLYLKNLCYQTSKQQSNMEKFEQNAAS 1563
            MIEILQSSTIHGVSHIHGAKSQITKVLWIFLFIFGIIGIFVNIVFVIIKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIINGKRNTDYELEERTIAMSSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNIPCFTFHIDKSKFLNQNQIKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGV RKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLPIYKNETGPPRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLKCQDYRFIKCNEVKYKIEKDKELFVEFWSGLTNQRRNELLKKVSYYLMEKFDIKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELMYLYLKNLCYQTSKQQSNMEKFEQNAAS
Sbjct:    1 MIEILQSSTIHGVSHIHGAKSQITKVLWIFLFIFGIIGIFVNIVFVIIKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIINGKRNTDYELEERTIAMSSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNIPCFTFHIDKSKFLNQNQIKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGVLRKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLPIYKNETGPPRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLKCQDYRFIKCNEVKYKIEKDKELFVEFWSGLTNQRRNELLKKVSYYLMEKFDIKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELMYLYLKNLCYQTSKQQSNMEKFEQNAAS 521
[Close]
BLAST of Degenerin unc-8 vs. Planmine SMEST
Match: SMESG000016391.1 (SMESG000016391.1)

HSP 1 Score: 756.133 bits (1951), Expect = 0.000e+0
Identity = 379/484 (78.31%), Postives = 423/484 (87.40%), Query Frame = 1 
Query:    1 MIEILQSSTIHGVSHIHGAKSQITKVLWXXXXXXXXXXXXXXXXXXXXKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIINGKRNTDYELEERTIAMSSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNIPCFTFHIDKSKFLNQNQIKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGVQRKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLPIYKNETGPPRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLKCQDYRFIKCNEVKYKIEKDKELFVEFWSGLTNQRRNELLKKVSYYLMEKFDIKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSV 1452
            MIE+++SSTIHGVSHIH AKSQI K+LWIFLFIFGIIGIF+NI F++IKYFSNPVL SH L+HEPFIWPD+TFCKPTAP+YFGENSQAY HW+ V  +T+RIVERLANET+VFKII GK NTDYELEERTIAMSSADPYKLK +DF+ H++ I FNK+Q GIYY++D S  AVTS  EDLKPLFT  LVQI NNIPCFTFHID+SKF+NQN IKS++F LKFNLESY LFNSSYLHRSVFLYI+NRN  P +NEILLAPGFNNI+SLSQSRYE +GVQRKCRN+ +  ELYD LL+STSTFEGHYDDCK+VESQ+LFV  C CYSPFLPIYKN+TG PRICLN TFYSE+EI++NAKCM DV+ +FQSYKAF N     C+ YRFIKC EVKY IEK+KELFVEFWSGLTNQRR  L+KK S +L EKFD K YFERMRDNFIGI I RE QKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSV
Sbjct:    1 MIELIESSTIHGVSHIHSAKSQIIKLLWIFLFIFGIIGIFINIAFILIKYFSNPVLFSHILNHEPFIWPDMTFCKPTAPFYFGENSQAYNHWAEVVSKTKRIVERLANETKVFKIIIGKNNTDYELEERTIAMSSADPYKLKVDDFQSHVIGINFNKIQEGIYYNVDYSVKAVTSIDEDLKPLFTTQLVQIGNNIPCFTFHIDRSKFINQNSIKSVNFNLKFNLESYFLFNSSYLHRSVFLYISNRNSFPRRNEILLAPGFNNIISLSQSRYELKGVQRKCRNEKYVVELYDALLKSTSTFEGHYDDCKRVESQRLFVRNCNCYSPFLPIYKNKTGQPRICLNGTFYSEEEILQNAKCMVDVFRRFQSYKAFMNILHSNCEHYRFIKCKEVKYGIEKEKELFVEFWSGLTNQRRQRLIKKYSRHLTEKFDNKKYFERMRDNFIGIAIKRETQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSV 484
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BLAST of Degenerin unc-8 vs. Planmine SMEST
Match: SMESG000069546.1 (SMESG000069546.1)

HSP 1 Score: 734.947 bits (1896), Expect = 0.000e+0
Identity = 380/521 (72.94%), Postives = 438/521 (84.07%), Query Frame = 1 
Query:    1 MIEILQSSTIHGVSHIHGAKSQITKVLWXXXXXXXXXXXXXXXXXXXXKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIINGKRNTDYELEERTIAMSSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNIPCFTFHIDKSKFLNQNQIKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGVQRKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLPIYKNETGPPRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLKCQDYRFIKCNEVKYKIEKDKELFVEFWSGLTNQRRNELLKKVSYYLMEKFDIKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELMYLYLKNLCYQTSKQQSNMEKFEQNAAS 1563
            MIEILQSSTIHGVSHIHGAKS+ITK+LWI LFI G+IGIFVNIVFVI++YFSNPVLIS  LDHEPFIWPD+TFCKPTAPYYF ENSQ Y HW+ VF RTRRIVERL+NETE FKI+NGKRNTDYELEERTIAMSSADPYKLK ++F YHIM I FN+++    Y  DN      +F EDLKPLFTAPLVQI+NNIPCFTFHI+KSK L+Q+ I SI F+L FN++SY+LFNSS+LHRSVFLYITNRNGIP K E+LL PGFNNIVSLSQ+R+EYRGVQRKCRNK ++ ELYD LLQSTS FEG+Y DC KVESQKL V  CKCY+PFLPIYKNETG PRICLNATFYSE+EI++NAKCM +   KF+S+  +R  +  KCQDY+ IKCNEVKYKIEK+K LF E  SG T QRR +++K  S +  ++ D ++ FER+RDN+I ITI REF KGDLYKEEYEYPFS+LLSDIGGLMGLWLGMSVVGLFEIFE++Y+Y  NL    +K+QSN+   EQNAAS
Sbjct:    1 MIEILQSSTIHGVSHIHGAKSRITKMLWIILFILGLIGIFVNIVFVIMRYFSNPVLISRNLDHEPFIWPDITFCKPTAPYYFVENSQPYNHWTEVFRRTRRIVERLSNETEFFKIMNGKRNTDYELEERTIAMSSADPYKLKMDNFSYHIMLIVFNRIRTYTNYISDNEFFE--NFHEDLKPLFTAPLVQIQNNIPCFTFHINKSKSLHQDNITSIRFHLNFNIKSYMLFNSSFLHRSVFLYITNRNGIPQKYEMLLEPGFNNIVSLSQNRFEYRGVQRKCRNKTYKVELYDALLQSTSIFEGYYADCMKVESQKLCVSNCKCYNPFLPIYKNETGSPRICLNATFYSEEEILKNAKCMVNRLRKFKSFFLYRRFFNPKCQDYQLIKCNEVKYKIEKEKLLFAELSSGFTTQRRRKVIKGFSKWF-QRIDNRSDFERIRDNYIVITIKREFPKGDLYKEEYEYPFSQLLSDIGGLMGLWLGMSVVGLFEIFEIIYMYFTNL----NKKQSNIRICEQNAAS 514
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BLAST of Degenerin unc-8 vs. Planmine SMEST
Match: SMESG000017668.1 (SMESG000017668.1)

HSP 1 Score: 733.021 bits (1891), Expect = 0.000e+0
Identity = 375/522 (71.84%), Postives = 433/522 (82.95%), Query Frame = 1 
Query:    1 MIEILQSSTIHGVSHIHGAKSQITKVLWXXXXXXXXXXXXXXXXXXXXKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIINGKRNTDYELEERTIAMSSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNI-PCFTFHIDKSKFLNQNQIKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGVQRKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLPIYKNETGPPRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLKCQDYRFIKCNEVKYKIEKDKELFVEFWSGLTNQRRNELLKKVSYYLMEKFDIKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELMYLYLKNLCYQTSKQQSNMEKFEQNAAS 1563
            MIEILQSSTIHGVSHI GAKS+ITK+LWI +FI GII IFVNIVFVI+KYFSNPVLISHKLDHEPFIWPD+TFCKPTAPYYF ENSQ Y HW+ VF RTRRI+ERL NETE F II  + NTDYELEERTIAMSSADPYKLK N++RYHI  I F ++ R + Y+ +     +  F EDL  LFT+PLVQI NN+ PCFTFH+DKSK LNQN IKS  F+L  N++SYLLFNSS  HRSVFLYITNRNGIP   E+LL PGFNNI+SLSQ+RYEYRGV RKCR K +E ELYD LLQSTSTFEG YDDC+KVE+QKLFV  C CYSPFLPIYKN+TGPPRICLNATFYSE+++++NA CM + + K +S +AFRN YRLKCQDY+ I+CN+VKYK EK+K LF E WSG T +RR+++LK+ S +  ++ D ++ FER+RDN+I ITINREF KGDLYKEEYEYPFS+LLSDIGGLMGLWLGMSVVGLFEIFE++YLYL  L    SK Q+NMEK EQN AS
Sbjct:    1 MIEILQSSTIHGVSHIQGAKSRITKMLWIIIFILGIILIFVNIVFVIMKYFSNPVLISHKLDHEPFIWPDITFCKPTAPYYFVENSQIYNHWTEVFRRTRRILERLTNETEAFSIITKQINTDYELEERTIAMSSADPYKLKVNNYRYHIKGITFLRIPRYVNYYANTE--VMEFFEEDLMSLFTSPLVQIHNNMFPCFTFHVDKSKSLNQNYIKSFFFHLNLNIKSYLLFNSSAFHRSVFLYITNRNGIPQTYEMLLEPGFNNIISLSQTRYEYRGVHRKCRKKTYEVELYDALLQSTSTFEGDYDDCRKVETQKLFVSKCNCYSPFLPIYKNKTGPPRICLNATFYSEEDVLKNANCMVNNFRKIESVEAFRNLYRLKCQDYKLIECNKVKYKFEKEKLLFTELWSGFTTKRRHKMLKQFSNWF-QRIDNRSDFERIRDNYIVITINREFPKGDLYKEEYEYPFSQLLSDIGGLMGLWLGMSVVGLFEIFEIIYLYLIKL----SKHQTNMEKCEQNDAS 515
[Close]
BLAST of Degenerin unc-8 vs. Planmine SMEST
Match: SMESG000017657.1 (SMESG000017657.1)

HSP 1 Score: 533.872 bits (1374), Expect = 0.000e+0
Identity = 281/501 (56.09%), Postives = 366/501 (73.05%), Query Frame = 1 
Query:    1 MIEILQSSTIHGVSHIHGAKSQITKVLWXXXXXXXXXXXXXXXXXXXXKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIINGKRNTDYELEERTIAMSSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNIPCFTFHIDKSKFLNQNQIKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGVQRKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLPIYKNETGPPRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLKCQDYRFIKCNEVKYKIEKDKELFVEFWSGLTNQRRNELLKKVSYYLMEKFDIKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELMYLYLKNL 1503
            M E+L+SSTIH VSHI+GAKS+ TKVLW F+FIFGIIGI VNIV+VI  YFS+P+L+SH L+ E FIWPD+T CKP AP+YF ++S  Y +W  ++ +T ++V RLANETEV K+I    + D E EERT+ MS+ADP KLKT+D R H+ +IY+N+  +G      +SG    +   DLK  FT   VQI NNIPCFTF I+K+K + +N +  + FYLKFN +SYLLFNSSY   SVFL++ N N IP    + L P +N+I+SLSQSRY Y+ ++ KCR +I+  ELYD  LQS S FEG++ DCKKV+SQ++FV  CKCYSPFLPIYKN TGPPRICLNAT YSEDEI++NA CM D Y +F       N     C+ YR  KC+E++YK+ K+KELF EF++G +N+RR +++K +     ++   +  +  +RDNF+ + I+RE +KGDL+KEE+EY   ELLSDIGGLMGLWLGMS+VGLFEIFE+ YLYL NL
Sbjct:    2 MDELLESSTIHVVSHIYGAKSRYTKVLWSFVFIFGIIGISVNIVYVINNYFSSPILLSHTLNSEEFIWPDITLCKPVAPFYFEKDSDTYKYWMEIYRKTSKVVRRLANETEVLKLIGMIGDGDSEFEERTVMMSTADPLKLKTDDIRNHLFSIYYNENHKG------DSGFGDVT---DLKSAFTTQYVQIFNNIPCFTFQINKTKIIQKNLV-FLLFYLKFNFDSYLLFNSSYSPPSVFLFLNNANEIPQSKAMTLIPSYNHIISLSQSRYIYKNIKEKCREEIYYVELYDVTLQSYSKFEGNFVDCKKVKSQEMFVSQCKCYSPFLPIYKNATGPPRICLNATLYSEDEIIQNAYCMVDAYKRF-------NENNSSCEIYRLAKCDEIRYKMGKEKELFTEFFNGNSNERRRKMIKIIFSQFTQQPVSEIPYNIIRDNFMQLKISRETEKGDLFKEEFEYRMFELLSDIGGLMGLWLGMSIVGLFEIFEITYLYLINL 485
The following BLAST results are available for this feature:
BLAST of Degenerin unc-8 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
S5W2R27.824e-16851.61Asic OS=Schmidtea mediterranea OX=79327 PE=2 SV=1[more]
A0A183A5V19.024e-7732.69Uncharacterized protein OS=Echinostoma caproni OX=... [more]
A0A4E0RSD98.797e-7332.44Degenerin unc-8 OS=Fasciola hepatica OX=6192 GN=D9... [more]
A0A504YRR85.982e-7232.25Degenerin unc-8 OS=Fasciola gigantica OX=46835 GN=... [more]
A0A5J4NUF12.045e-7131.48Uncharacterized protein OS=Paragonimus westermani ... [more]
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BLAST of Degenerin unc-8 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO421371.254e-642.31Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO394466.675e-625.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Degenerin unc-8 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
asic1a9.471e-629.90acid-sensing ion channel 1 [Source:NCBI gene;Acc:1... [more]
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BLAST of Degenerin unc-8 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000017678.10.000e+099.81SMESG000017678.1[more]
SMESG000016391.10.000e+078.31SMESG000016391.1[more]
SMESG000069546.10.000e+072.94SMESG000069546.1[more]
SMESG000017668.10.000e+071.84SMESG000017668.1[more]
SMESG000017657.10.000e+056.09SMESG000017657.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002847 ID=SMED30002847|Name=Degenerin unc-8|organism=Schmidtea mediterranea sexual|type=transcript|length=1604bp
ATGATAGAAATATTACAAAGCAGCACAATTCACGGAGTCAGTCACATTCA
CGGTGCAAAAAGTCAAATTACCAAGGTGTTATGGATTTTTCTTTTTATTT
TTGGTATTATTGGAATATTTGTTAACATTGTATTTGTAATAATAAAATAT
TTTTCTAATCCAGTTTTAATTAGTCATAAGTTGGATCACGAGCCGTTCAT
TTGGCCTGATGTAACATTTTGTAAGCCAACTGCGCCGTATTATTTTGGAG
AAAATTCACAAGCATACACTCATTGGTCACATGTATTTTGGAGAACAAGA
AGAATTGTTGAACGATTAGCAAATGAAACAGAAGTTTTTAAAATAATAAA
TGGCAAAAGAAATACGGATTATGAATTAGAAGAGAGAACTATAGCTATGT
CGAGCGCGGATCCCTATAAATTGAAAACGAATGATTTCCGATATCACATA
ATGGCAATTTATTTTAACAAAATGCAAAGAGGAATTTATTATCATATTGA
TAATTCTGGAATAGCGGTGACATCCTTTGCCGAAGATTTGAAGCCATTAT
TTACAGCTCCACTCGTTCAAATTCGAAACAATATTCCATGTTTCACTTTC
CATATTGATAAATCTAAATTTTTAAATCAAAATCAAATTAAATCAATTAG
TTTTTATTTAAAATTTAACCTCGAAAGTTATTTATTGTTTAATTCAAGCT
ATTTGCACCGTTCGGTATTCCTATATATTACAAATAGAAATGGAATTCCT
CATAAAAATGAAATATTGCTAGCACCTGGCTTTAACAATATAGTTTCCCT
CTCGCAGAGCCGATACGAATATAGAGGGGTTCAACGAAAATGTCGAAATA
AAATATTTGAAACCGAATTGTATGACGGGCTTTTACAATCAACCTCAACC
TTTGAAGGTCATTATGATGACTGCAAGAAGGTTGAAAGCCAGAAATTGTT
TGTGGGTATTTGTAAATGTTACAGTCCGTTTTTGCCGATTTACAAAAATG
AAACTGGACCTCCGAGAATTTGTTTGAATGCGACATTTTATTCCGAAGAT
GAAATCGTTCGAAATGCAAAATGTATGACTGATGTTTATACGAAATTTCA
AAGTTATAAAGCATTCCGAAATCATTATCGTTTGAAGTGTCAAGATTACA
GATTTATTAAGTGCAATGAAGTGAAGTATAAAATTGAAAAAGATAAAGAA
TTATTTGTCGAGTTCTGGAGTGGATTGACAAACCAAAGACGTAATGAATT
ATTAAAAAAAGTTTCCTACTATCTCATGGAAAAATTTGATATTAAAAATT
ATTTTGAACGAATGCGAGATAATTTTATTGGAATTACAATAAATCGGGAA
TTTCAAAAAGGGGATTTATATAAAGAAGAATATGAATATCCATTTTCTGA
ACTATTGTCAGACATTGGAGGATTAATGGGACTCTGGCTAGGGATGAGTG
TCGTTGGTTTGTTTGAAATATTTGAATTAATGTATTTATATTTAAAAAAT
TTATGCTATCAAACAAGCAAGCAACAATCAAATATGGAAAAGTTTGAACA
AAATGCTGCTTCCCTATTATGACATTTGACTTTTTTGCTGAATCTTTATT
CTTT
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protein sequence of SMED30002847-orf-1

>SMED30002847-orf-1 ID=SMED30002847-orf-1|Name=SMED30002847-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=524bp
MIEILQSSTIHGVSHIHGAKSQITKVLWIFLFIFGIIGIFVNIVFVIIKY
FSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTR
RIVERLANETEVFKIINGKRNTDYELEERTIAMSSADPYKLKTNDFRYHI
MAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNIPCFTF
HIDKSKFLNQNQIKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIP
HKNEILLAPGFNNIVSLSQSRYEYRGVQRKCRNKIFETELYDGLLQSTST
FEGHYDDCKKVESQKLFVGICKCYSPFLPIYKNETGPPRICLNATFYSED
EIVRNAKCMTDVYTKFQSYKAFRNHYRLKCQDYRFIKCNEVKYKIEKDKE
LFVEFWSGLTNQRRNELLKKVSYYLMEKFDIKNYFERMRDNFIGITINRE
FQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELMYLYLKN
LCYQTSKQQSNMEKFEQNAASLL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR001873ENaC
Vocabulary: molecular function
TermDefinition
GO:0005272sodium channel activity
Vocabulary: biological process
TermDefinition
GO:0006814sodium ion transport
GO:0006810transport
GO:0006811ion transport
GO:0035725sodium ion transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001873Epithelial sodium channelPRINTSPR01078AMINACHANNELcoord: 473..489
score: 49.88
coord: 25..42
score: 18.67
coord: 314..331
score: 30.44
coord: 459..473
score: 36.53
IPR001873Epithelial sodium channelPFAMPF00858ASCcoord: 6..493
e-value: 9.1E-45
score: 153.4
IPR001873Epithelial sodium channelPANTHERPTHR11690AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATEDcoord: 7..518
NoneNo IPR availableGENE3DG3DSA:1.10.3590.10coord: 78..238
e-value: 2.9E-26
score: 94.3
NoneNo IPR availableGENE3DG3DSA:1.10.287.820coord: 274..388
e-value: 2.9E-26
score: 94.3
NoneNo IPR availableGENE3DG3DSA:2.60.470.10coord: 55..461
e-value: 2.9E-26
score: 94.3
NoneNo IPR availableGENE3DG3DSA:1.10.287.770coord: 25..491
e-value: 2.9E-26
score: 94.3
NoneNo IPR availableTMHMMTMhelixcoord: 476..498
NoneNo IPR availableTMHMMTMhelixcoord: 26..48