Amine oxidase

Query:  226 HNFAI----FESSYKIGGRIQTVK-FGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNK-----LKNILEYVNEKYYDKVI--------DPEKNFKDLLMESSDYFESMTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNE-----LIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERF-SGSFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            HNF I     E+  +IGGR+   K F G     G   V+G   NP+  +   + + +           F    D  Q+   + +  ++K        +L+ V+E   DK            E+ +K  + ES   F   ++LE  VL    + +E   G+ LH++SA +   H+E   F +   +  ++ P G   +I  L +     I+LK  V+ ID+S +   V++ T +   +  + V++T+P  LL + +I+F P L  +K+ A   +      ++  +FP RFW  K        +V P         +F+      ++  ++ + ++    +G    S R   +K+ L + +  +++ +F           F+T W ++ +   ++S V  G S    + + + + G + FAGE+       T+ GAY+SG+  A
Sbjct:  402 HNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQLGISMHK---------FGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQF---SELEGQVLQFHLSNLEYACGSNLHQVSARS-WDHNEF--FAQFAGDHTLLTP-GYSVIIEKLAEGL--DIQLKSPVQCIDYSGDE--VQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFY------DMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMA-TLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREA 816          

Query:  226 HNFAI----FESSYKIGGRIQTVK-FGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNK-----LKNILEYVNEKYYDKVI--------DPEKNFKDLLMESSDYFESMTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNE-----LIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERF-SGSFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            HNF I     E+  +IGGR+   K F G     G   V+G   NP+  +   + + +           F    D  Q+   + +  ++K        +L+ V+E   DK            E+ +K  + ES   F   ++LE  VL    + +E   G+ LH++SA +   H+E   F +   +  ++ P G   +I  L +    Q+K   +V+ ID+S +   V++ T +   +  + V++T+P  LL + +I+F P L  +K+ A   +      ++  +FP RFW  K        +V P         +F+      ++  ++ + ++    +G    S R   +K+ L + +  +++ +F           F+T W ++ +   ++S V  G S    + + + + G + FAGE+       T+ GAY+SG+  A
Sbjct:  402 HNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQLGISMHK---------FGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQF---SELEGQVLQFHLSNLEYACGSNLHQVSARS-WDHNEF--FAQFAGDHTLLTP-GYSVIIEKLAEGLDIQLK-SPQVQCIDYSGDE--VQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFY------DMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMA-TLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREA 817          

Query:  787 IKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNE-----LIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERF-SGSFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            I+LK  V+ ID+S +   V++ T +   +  + V++T+P  LL + +I+F P L  +K+ A   +      ++  +FP RFW  K        +V P         +F+      ++  ++ + ++    +G    S R   +K+ L + +  +++ +F           F+T W ++ +   ++S V  G S    + + + + G + FAGE+       T+ GAY+SG+  A
Sbjct:  360 IQLKSPVQCIDYSGDE--VQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFY------DMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMA-TLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREA 584          

Query:  229 NFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHG-KKGNPIYDILVNIDVPLELGQPIENDILFVWD--------------TDSCQDITE---LFNERVNKLKNIL-----------EYVNEKYYDKV---IDPEKNFKDLLMESSDYFESMTDLERTVLYT-CMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDF-KDQIKLKHKVKVIDWSK---------ESEVVKIVTDNDEEFHCKNVIITLPSELLARESIK--FLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVI-KNVDPVNELI-------FWQNCSCQNLCAEEDNILICHFTSGSQQGSSRF--DVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSVGP--------LHFAGESVIVELIGTMQGAYISGIEAAKHSL 1479
            +  + E++ + GGRI++ +  G +   G  W+HG  +GNP++ +     +  E     EN ++                  + S Q + E   LF   +++ +  L           EY+ ++    V    + E+  K  L   + +F    +LE  V  T  M++   AP  E + L  +       F +G              L N +     +D +  +  VK I W+          E+  V +  ++ + F   +VI+T+P   L RE +   F P LP EK  A + +      ++F +F   FW     LIQ++ ++  P+ +         F +      L A     ++C F +G +   S F   +  EE+   +T+ ++R+  +        +  + W S  ++ GS+S V+ G +  D++ L + +          + FAGE+       T  GA +SG   A   L
Sbjct:   40 HLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFF----NLECCVSGTHSMDLVALAPFGEYTVLPGLD----CTFSKGYQG-----------LTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFL-REHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLE---SEFMETLSDEEVLLCLTQVLRRVTGNPRLPAPKSVLRSRWHSAPYTRGSYSYVAVGSTGGDLDLLAQPLPADGAGAQLQILFAGEATHRTFYSTTHGALLSGWREADRLL 497          

Query:  706 GILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILIC---HFTSGSQQGSSRFDVEK--EELTEIVTESMKRMFPHTYC---APSDVLFITH-----WDSERFSGS--FSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAAKHSL 1479
            G ++ RI+D LG             DQ+KL H V  +D S ++ +++  T N E + CK VI  +P  L A+  I F P+LP E+    + +P     +    +   FW +K++                   C C  +  E+  I I        GS      F + +  + L ++  E  K+     Y       + L   H     W  E++SG    +   PGI       + + VG + FAG     +  G M+GA  +G  AA+  L
Sbjct:  224 GQVSERIMDLLG-------------DQVKLNHPVTHVDQSSDNIIIE--TLNHEHYECKYVINAIPPTLTAK--IHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDY-------------------CGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVL 460          

Query:  238 IFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQ---PI--ENDILFVWDTDSCQDITEL-FNERVNKLKNILEYVNEKYYDKV---IDPEKNFKDLLMESSDYFESMTDLERTVLYT------------CMEIYRGAPLHELSALAEIQHDEVYDFEEGILNF---RIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDE----EFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWP-------EKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTES---------MKRMFPHTYCAPSDVLFITHWDSERFSGSFSKVSPGISKVDI--EELCKSVG-PLHFAGESVIVELIGTMQGAYISGIEAA 1467
            +FE+  + GGR+   +  G     G   + G   NPI  +   I +         P+  EN   F  +     D  +L +N  ++ ++N  +Y +++ +  V   +   ++F ++  + S    S  DL+   LYT             +E   G  +  LSA       + YD  E   NF     V   G  ++I++L       I+L   VK IDW ++   VKI  +N E    EF  K VI T  S L +  S  F+P LPIEK  A   +      ++  KF  RFW          E+  +V       +    + + S ++   E+  +L+ + T+           E   L  ++TES         +++MFP     P   + ++HW ++RF G      P  S  D    +L KS+   L+FAGE  I     TM GAYISG+  A
Sbjct:  379 LFEAKDRFGGRMMDDQSLGVSVGKGAQIIVGNINNPITLLCEQIGIKYRNSNFFCPLIDENGRCFTLERKELDDQVDLHYNNVLDAIRN--KYQSDRNFPDVPLEVTNFRHFTEMFSKMSSGLLSAADLDS--LYTPEFEKLLDFHLGNLEFSCGTHVSNLSA-------KDYDHNEKFGNFAGEHAVITDGAQRIIDFLATGL--DIRLNCPVKCIDWGRDDRKVKIFFENAEQAAEEFD-KVVITTSLSVLKSNHSKMFVPPLPIEKQKAIDDLGAGLIEKIAVKFDRRFWDTVDADGLRTEYFGKVSDCKTDRSLFNIFYDFSGKDPNGEDTFVLMSYVTA-----------EHVNLVNVLTESEVADKFCATLRKMFPSAVINPLGHM-MSHWGADRFVGMSYTFVPFGSDGDATYNQLKKSIDEKLYFAGEHTIAAEPQTMAGAYISGLREA 809          

Query:  739 GGLKLINYLCKDFKDQIKLKHKVKVIDWSK-ESEVVKIVTDND--EEFHCKNVIITLPSELLARESIK------FLPKLPIEKLSAWKYVP--GVNYCRLFAKFPTRFWPE---KEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERF---SGSFSKVSPGISKVD--IEELCKSVG--PLHFAGESVIVELIGTMQGAYISGIEAA 1467
            G  +L+  L +  K  I+LKH+V  ID+S  E  ++K+  +N   EE     V+ TLP  +L +  I       F P LP +K+ A + +    VN C L  +F   FW     +   + V  N+     +  W +     +        +C +  G +   +  ++  + + +    ++++ F +          IT W  +     SG+F  +    +  D  +E L  S G   ++FAGE        T+QGA++SG  AA
Sbjct:  423 GIAELLTQLSEKRKLDIRLKHRVLDIDYSGFEHVLLKVQRENGDIEEMKAAFVVSTLPIGVLKKTIIADERAPTFTPSLPDKKVEAIRNIGCGSVNKCIL--EFDRVFWTANGGRNQFVTVSPNIKTRGSMNIWSSVPGSKV--------LCTYIVGEE---AMLELPDDVIIQNAMINLQKAFGNNCPRAPISAHITRWHDDELAFGSGAFMSLRTETTSFDDVMEPLKTSDGMSRVYFAGEHTCSSYTSTIQGAWMSGARAA 673          

Query:  739 GGLKLINYLCKDFKDQIKLKHKVKVIDWSK-ESEVVKIVTDND--EEFHCKNVIITLPSELLARESIK------FLPKLPIEKLSAWKYVP--GVNYCRLFAKFPTRFWPE---KEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERF---SGSFSKVSPGISKVD--IEELCKSVG--PLHFAGESVIVELIGTMQGAYISGIEAA 1467
            G  +L+  L +  K  I+LKH+V  ID+S  E  ++K+  +N   EE     V+ TLP  +L +  I       F P LP +K+ A + +    VN C L  +F   FW     +   + V  N+     +  W +     +        +C +  G +   +  ++  + + +    ++++ F +          IT W  +     SG+F  +    +  D  +E L  S G   ++FAGE        T+QGA++SG  AA
Sbjct:  423 GIAELLTQLSEKRKLDIRLKHRVLDIDYSGFEHVLLKVQRENGDIEEMKAAFVVSTLPIGVLKKTIIADERAPTFTPSLPDKKVEAIRNIGCGSVNKCIL--EFDRVFWTANGGRNQFVTVSPNIKTRGSMNIWSSVPGSKV--------LCTYIVGEE---AMLELPDDVIIQNAMINLQKAFGNNCPRAPISAHITRWHDDELAFGSGAFMSLRTETTSFDDVMEPLKTSDGMSRVYFAGEHTCSSYTSTIQGAWMSGARAA 673          

Query:  229 NFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERV-----NKLKNILEYVNEKYYDKVI-------DPEKN------FKDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELS-ALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQI---KLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLAR-ESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFT-SGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSVGP--------LHFAGESVIVELIGTMQGAYISGIEAA 1467
            ++ IFE S +IGGR+   ++       G  +V+G   N +Y+++   D+  +  +P  +D+   W  D    IT +    V     +K  + + Y+N   Y+K I       + E N       +D+     + +ES+ ++ +    T       +P+ ELS +   I  D   + +  +LN +     G  +++    KDF+ +I    ++   +VI+  KE E + +   N E  H    I+T     L +     F P+L   K  A   +   N  ++F ++   +W      I ++ + +  + ++F  +   +       NIL+C    SG ++   + D E + L +  T    ++  +     S  ++  +W ++ F+ GS+S ++PG  ++  E++C    P        + FAGE     +  T  GA  SG+  A
Sbjct:   26 DYTIFEGSNRIGGRVYPFEYQDGYLHFGAEYVNGVD-NEVYNLVEKYDL-FDKTKPRTDDL---WMLDQDNSITLVNGHLVPKKILDKFNDYIRYLNVALYEKSIKINQLSVENEINNQFIEFLRDVPENDHEIYESLINVYKNYFQTEW----SSPVGELSLSNLSIWDDGTEEEDSAVLNKQ-----GFYEIL----KDFRSKIPAGNIRLNCEVIN-VKEEENIMVTLKNGEVLHFDACIVTCSLGYLKKHHKTLFTPQLTSVKQDAINRMGFGNNLKVFLEYSDSWWNSLN-TILILTHGENEDFMVFQPSSWAE-------NILLCWIAGSGPKKICDKTDFELKILLD--THLHDQLKNYLDVKASVKIYRKNWINDEFTLGSYSYLTPG--QIVGEDICILAQPVLKDNNPVICFAGEHTDSTMYQTTVGAVRSGLREA 440          

Query:  220 GQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPL-ELGQPIENDILFVWDTDSCQDITELFNERVNKLKNIL-------------------EYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEG--ILNFRIVDPLGGLKLINYLCKD---------FKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIK-FLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPE 1038
            G  N  + E+  ++GGRI T+ F   +   G  W HG++ N +Y++    D  L E   P+  +   V    S  D+     E  ++LK I+                    Y+  K+YD +  PE +  D  + +S++F +    E +V  +         L ++S    + + E     EG  +LN++     G ++L+  L +           + ++ L  +V  I+W++    V++   N E     +V++T+   +L  + ++ F P+LP+EK  A   +      ++F +FP  FWPE
Sbjct:   66 GFQNVLVVEAEDRLGGRIHTIPFADNVIDLGAQWCHGERDNIVYELTRKQDEELLESTGPVYENYECV---RSNGDVVP--EEVSSRLKAIVGDSLVTRQLELRHCSGSLGSYLTNKFYDTLRRPENSDIDAEV-ASEFFVNYQKFENSVEAS-------DTLEQVSGRGYLDYWEC----EGDILLNWK---DKGYVELLRLLMRSRELNVEHGVLEQRLLLGTRVVKINWNRNDGRVELQMSNGETCIADHVVVTVSLGVLKDQHLRLFEPQLPVEKQRAIDGLAFGTVNKIFVEFPEAFWPE 350          

Query:  220 GQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPL-ELGQPIENDILFVWDTDSCQDITELFNERVNKLKNIL-------------------EYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEG--ILNFRIVDPLGGLKLINYLCKD---------FKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIK-FLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPE 1038
            G  N  + E+  ++GGRI T+ F   +   G  W HG++ N +Y++    D  L E   P+  +   V    S  D+     E  ++LK I+                    Y+  K+YD +  PE +  D  + +S++F +    E +V  +         L ++S    + + E     EG  +LN++     G ++L+  L +           + ++ L  +V  I+W++    V++   N E     +V++T+   +L  + ++ F P+LP+EK  A   +      ++F +FP  FWPE
Sbjct:   32 GFQNVLVVEAEDRLGGRIHTIPFADNVIDLGAQWCHGERDNIVYELTRKQDEELLESTGPVYENYECV---RSNGDVVP--EEVSSRLKAIVGDSLVTRQLELRHCSGSLGSYLTNKFYDTLRRPENSDIDAEV-ASEFFVNYQKFENSVEAS-------DTLEQVSGRGYLDYWEC----EGDILLNWK---DKGYVELLRLLMRSRELNVEHGVLEQRLLLGTRVVKINWNRNDGRVELQMSNGETCIADHVVVTVSLGVLKDQHLRLFEPQLPVEKQRAIDGLAFGTVNKIFVEFPEAFWPE 316          

Query:  220 GQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITE--LFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLL-MESSDYFESMTDLERTVLYTCMEIYRG--APLHELSALAEIQ---HDEVYDFE-EGILNFRIVDPLGGLKLINYLCKD-------FKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIK-FLPKLPIEKLSAWKYVPGVNYCRLFAKFPT----RFWPEKE--WLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSE-RFSGSFSKVSPGISKV-----DIEELCKSV---GPLHFAGESVIVELIGTMQGAYISGIEAAK 1470
            G  N  + E+  +IGGR+ T+ F   +   G  W HG+KGN +YD + ++++ LE+ +P        ++T  C    +  L ++  ++LK I +        +++D E +  D + M+       +  ++RT+    +E++    A +     L E+    H E +  E E +LN++       LKL+    +D        KD ++L  ++  I+W    E+  +   N E     +VI T+   +L  +  K F+P LP  K+ A + +      + F +F        WP     WL + ++ +   +EL + ++       + +  IL         +      + +E + E +    ++  P     P  +L  T W +   F GS++  S     +     D+E   + V     L FAGES       T+ GA  +G   A+
Sbjct:   38 GFRNVLLLEAEDRIGGRVHTIPFADNVVDLGAQWCHGEKGNVVYDKVKDLNL-LEVTEP-------HYETFRCVRSNKEVLPDDLADQLKTIADMSIPDRQAELLDFEGSLGDYINMKYWKELAKLPPIDRTIAEEFLEVFHKFEASVEAADHLFEVSGKGHLEYWLCEGELLLNWKDKGYKRFLKLLMKAPEDQSEDLGILKDHVRLNRRIAEINWKGADELT-VRCWNGEVITADHVICTVSLGVLKEQHPKLFVPALPAAKVRAIEGLKLGTVDKFFLEFENPPLPGDWPGFNCLWLKEDLEELR-ASELFWLESVFGFYPVSRQPRILQGWIIGPHARHME--TLTEERVLEGLLWLFRKFLPFETAHPVRML-RTQWHANPNFRGSYTFRSTYTDALRTGAWDLEAPLQDVCGRPRLQFAGESTHKHFYSTVHGAVETGWREAE 473          

Query:  220 GQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITE--LFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLL-MESSDYFESMTDLERTVLYTCMEIYRG--APLHELSALAEIQ---HDEVYDFE-EGILNFRIVDPLGGLKLINYLCKD-------FKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIK-FLPKLPIEKLSAWKYVPGVNYCRLFAKFPT----RFWPEKE--WLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSE-RFSGSFSKVSPGISKV-----DIEELCKSV---GPLHFAGESVIVELIGTMQGAYISGIEAAK 1470
            G  N  + E+  +IGGR+ T+ F   +   G  W HG+KGN +YD + ++++ LE+ +P        ++T  C    +  L ++  ++LK I +        +++D E +  D + M+       +  ++RT+    +E++    A +     L E+    H E +  E E +LN++       LKL+    +D        KD ++L  ++  I+W    E+  +   N E     +VI T+   +L  +  K F+P LP  K+ A + +      + F +F        WP     WL + ++ +   +EL + ++       + +  IL         +      + +E + E +    ++  P     P  +L  T W +   F GS++  S     +     D+E   + V     L FAGES       T+ GA  +G   A+
Sbjct:   38 GFRNVLLLEAEDRIGGRVHTIPFADNVVDLGAQWCHGEKGNVVYDKVKDLNL-LEVTEP-------HYETFRCVRSNKEVLPDDLADQLKTIADMSIPDRQAELLDFEGSLGDYINMKYWKELAKLPPIDRTIAEEFLEVFHKFEASVEAADHLFEVSGKGHLEYWLCEGELLLNWKDKGYKRFLKLLMKAPEDQSEDLGILKDHVRLNRRIAEINWKGADELT-VRCWNGEVITADHVICTVSLGVLKEQHPKLFVPALPAAKVRAIEGLKLGTVDKFFLEFENPPLPGDWPGFNCLWLKEDLEELR-ASELFWLESVFGFYPVSRQPRILQGWIIGPHARHME--TLTEERVLEGLLWLFRKFLPFETAHPVRML-RTQWHANPNFRGSYTFRSTYTDALRTGAWDLEAPLQDVCGRPRLQFAGESTHKHFYSTVHGAVETGWREAE 473          

Query:  208 LHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNE 507
            L ++G  N  +FE+  +IGGRI T+ F   +   G  W HG++GN +Y+ + ++DV    G     D +  +   + + +T++ N+ + +L N  E   E
Sbjct:   35 LLEQGFKNVLLFEAEDRIGGRINTILFANSLIDLGAQWCHGEEGNVVYEKVKDLDVLDRTG-----DYVVHFIRSNKEILTDVHNKALTELTNAFEVPGE 129          

Query:  208 LHKKGQHNFAIFESSYKIGGRIQTVK-FGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKL-KNILEYVNEKY---YDKVIDPEKNFKDLLMESSDYFE--------SMTDLERTVLYTCMEI----YRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDF-KDQIKLKHKVKVIDWS--------KESEVVKIVTDNDEEFHCKNVIITLPSELLARES-IKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIF--------WQNCSCQNLCA----EEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSE-RFSGSFSKVSPGISKVDIEE-LCKSVGPLH-----------FAGESVIVELIGTMQGAYISGIEAAKH 1473
            L + G  +  + E+  ++GGR+ T K F   I   G  W+HG+KGNP+Y I    ++  E    ++N  L      S       FNE    + K++++ V  ++    DK  D E + K   +    Y +        S T+  R V   C  +       + L+E+SA    Q     + E G  N   + P G   +++ L +D   + ++    VK I W         +E   V++V +N + F   +VI+T+   +L   +   F P LP +KLSA   +      ++F  F   FWP+    +Q++    P ++ ++        W+    + +            +C + +G ++      ++  E+ E+    ++          S  L I+ W S+ +  GS++ V  G+  V+  + L   + P H           FAGE+  V    T  GAY+SG   A+ 
Sbjct:   26 LIEAGFEDVLVLEAKERVGGRVHTTKPFTENIIEVGANWIHGQKGNPLYKIAKEKNLLSEGPSAMKNMCL----PHSVSPRDYFFNEDGKPVPKSVVDQVCARFSKLTDKAFDDELDGKYRKLTLGAYLDDAFGGTELSKTEDARQVYEWCKRVECTDEACSSLYEISA---SQLSNYTELEGGFFN--TLGPGGYQAILDVLLRDVPSEAVRCNAPVKTIRWDLVKEGQSEEEDHPVQVVCENGQTFEADHVIVTVSLGVLKEHAKTMFDPTLPEKKLSAINDLGFGIVNKIFLFFEKSFWPDDCAGVQLVWKEGPEDKDVYEDLSEGEDWKQTWFKKITGFDTVARHPTALCGWITG-REALYMESLQDREIQEVCVRLLRSSTGWPVPEVSKTL-ISRWGSDPQVRGSYTFVPDGVDGVEAHKALASPLPPKHRSRGRKNLQVLFAGEATHVNFYTTTHGAYLSGQREAER 488          

Query:  208 LHKKGQHNFAIFESSYKIGGRIQTVK-FGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKL-KNILEYVNEKY---YDKVIDPEKNFKDLLMESSDYFE--------SMTDLERTVLYTCMEI----YRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDF-KDQIKLKHKVKVIDWS--------KESEVVKIVTDNDEEFHCKNVIITLPSELLARES-IKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIF--------WQNCSCQNLCA----EEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSE-RFSGSFSKVSPGISKVDIEE-LCKSVGPLH-----------FAGESVIVELIGTMQGAYISGIEAAKH 1473
            L + G  +  + E+  ++GGR+ T K F   I   G  W+HG+KGNP+Y I    ++  E    ++N  L      S       FNE    + K++++ V  ++    DK  D E + K   +    Y +        S T+  R V   C  +       + L+E+SA    Q     + E G  N   + P G   +++ L +D   + ++    VK I W         +E   V++V +N + F   +VI+T+   +L   +   F P LP +KLSA   +      ++F  F   FWP+    +Q++    P ++ ++        W+    + +            +C + +G ++      ++  E+ E+    ++          S  L I+ W S+ +  GS++ V  G+  V+  + L   + P H           FAGE+  V    T  GAY+SG   A+ 
Sbjct:   26 LIEAGFEDVLVLEAKERVGGRVHTTKPFTENIIEVGANWIHGQKGNPLYKIAKEKNLLSEGPSAMKNMCL----PHSVSPRDYFFNEDGKPVPKSVVDQVCARFSKLTDKAFDDELDGKYRKLTLGAYLDDAFGGTELSKTEDARQVYEWCKRVECTDEACSSLYEISA---SQLSNYTELEGGFFN--TLGPGGYQAILDVLLRDVPSEAVRCNAPVKTIRWDLVKEGQSEEEDHPVQVVCENGQTFEADHVIVTVSLGVLKEHAKTMFDPTLPEKKLSAINDLGFGIVNKIFLFFEKSFWPDDCAGVQLVWKEGPEDKDVYEDLSEGEDWKQTWFKKITGFDTVARHPTALCGWITG-REALYMESLQDREIQEVCVRLLRSSTGWPVPEVSKTL-ISRWGSDPQVRGSYTFVPDGVDGVEAHKALASPLPPKHRSRGRKNLQVLFAGEATHVNFYTTTHGAYLSGQREAER 488          

Query:  208 LHKKGQHNFAIFESSYKIGGRIQTVK-FGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKL-KNILEYVNEKY---YDKVIDPEKNFKDLLMESSDYFE--------SMTDLERTVLYTCMEI----YRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDF-KDQIKLKHKVKVIDWS--------KESEVVKIVTDNDEEFHCKNVIITLPSELLARES-IKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIF--------WQNCSCQNLCA----EEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSE-RFSGSFSKVSPGISKVDIEE-LCKSVGPLH-----------FAGESVIVELIGTMQGAYISGIEAAKH 1473
            L + G  +  + E+  ++GGR+ T K F   I   G  W+HG+KGNP+Y I    ++  E    ++N  L      S       FNE    + K++++ V  ++    DK  D E + K   +    Y +        S T+  R V   C  +       + L+E+SA    Q     + E G  N   + P G   +++ L +D   + ++    VK I W         +E   V++V +N + F   +VI+T+   +L   +   F P LP +KLSA   +      ++F  F   FWP+    +Q++    P ++ ++        W+    + +            +C + +G ++      ++  E+ E+    ++          S  L I+ W S+ +  GS++ V  G+  V+  + L   + P H           FAGE+  V    T  GAY+SG   A+ 
Sbjct:   26 LIEAGFEDVLVLEAKERVGGRVHTTKPFTENIIEVGANWIHGQKGNPLYKIAKEKNLLSEGPSAMKNMCL----PHSVSPRDYFFNEDGKPVPKSVVDQVCARFSKLTDKAFDDELDGKYRKLTLGAYLDDAFGGTELSKTEDARQVYEWCKRVECTDEACSSLYEISA---SQLSNYTELEGGFFN--TLGPGGYQAILDVLLRDVPSEAVRCNAPVKTIRWDLVKEGQSEEEDHPVQVVCENGQTFEADHVIVTVSLGVLKEHAKTMFDPTLPEKKLSAINDLGFGIVNKIFLFFEKSFWPDDCAGVQLVWKEGPEDKDVYEDLSEGEDWKQTWFKKITGFDTVARHPTALCGWITG-REALYMESLQDREIQEVCVRLLRSSTGWPVPEVSKTL-ISRWGSDPQVRGSYTFVPDGVDGVEAHKALASPLPPKHRSRGRKNLQVLFAGEATHVNFYTTTHGAYLSGQREAER 488          

Query:  208 LHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHG-KKGNPIYDI-----LVNIDVPLELGQPIE--NDILFV--WDTDSCQDI-TELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLE-RTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGL---------KLINYLCKDFKDQIKLKHK-VKVIDWS---------KESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFL-PKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKN-----VDPVNEL-IFW-QNCSCQNLC--AEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSV-------GPLH--FAGESVIVELIGTMQGAYISGIEAAK 1470
            L K G HN  I E++ + GGRI+T + G  I   G  W+HG  K NP++ +     L++ +   E  Q I+     LFV  W T S + +  E     +     +LE  +++++    +P  +  + +   ++        E R      M +       E         D+V     G+  F +   L GL          L +++ K+    I L +K VK I W+           S  V I   N E F   +VI+T+P   + +    FL P  P+ KL + + +      ++F +F   FW E   LI ++        D V++L + W +  +   +    E    ++C + +G Q+      + + E+ + VT+ + R+F          L  + W  E +S GS+S V+ G S  DI+ L + +        PL   FAGE+       T+ GA +SG   A+
Sbjct:   30 LIKHGFHNVRIIEATARSGGRIRTGRLGDNIIEIGANWIHGPSKENPVFRLACDYQLLDKESMSEENQAIDIGGHPLFVPNWFTSSGRKLGPETMGPALEFFMTLLER-SQQFHSTGGEPLPSVGEFIKAEAERLAPEEWKEDRDNFAVRMAMINTLLKLECCVSGTHTMDDV-----GLGAFGMYTTLPGLDCTFPGGYEGLTDHMMKELPRDIVLYNKPVKCIHWNYTKNGPNTGGTSFPVTIECVNGETFAADHVIVTVPLGYMKKHQNTFLSPSFPLHKLHSIQRMGFGTNNKIFVEFEQPFWDEDCELIYLVWEDETHLTDVVSDLKMSWIRKLTGFTVLKPTERFGHVLCGWIAG-QESEYMESLSELEVLQTVTQ-LLRIFTGNPTIMPRKLLRSQWFHEPYSCGSYSYVAKGCSGYDIDNLAEPLPLKGSNSKPLQVLFAGEATHRSFFSTVHGALLSGWREAE 493          

Query:  208 LHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHG-KKGNPIYDI-----LVNIDVPLELGQPIE--NDILFV--WDTDSCQDI-TELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLE-RTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGL---------KLINYLCKDFKDQIKLKHK-VKVIDWS---------KESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFL-PKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKN-----VDPVNEL-IFW-QNCSCQNLC--AEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSV-------GPLH--FAGESVIVELIGTMQGAYISGIEAAK 1470
            L K G HN  I E++ + GGRI+T + G  I   G  W+HG  K NP++ +     L++ +   E  Q I+     LFV  W T S + +  E     +     +LE  +++++    +P  +  + +   ++        E R      M +       E         D+V     G+  F +   L GL          L +++ K+    I L +K VK I W+           S  V I   N E F   +VI+T+P   + +    FL P  P+ KL + + +      ++F +F   FW E   LI ++        D V++L + W +  +   +    E    ++C + +G Q+      + + E+ + VT+ + R+F          L  + W  E +S GS+S V+ G S  DI+ L + +        PL   FAGE+       T+ GA +SG   A+
Sbjct:   30 LIKHGFHNVRIIEATARSGGRIRTGRLGDNIIEIGANWIHGPSKENPVFRLACDYQLLDKESMSEENQAIDIGGHPLFVPNWFTSSGRKLGPETMGPALEFFMTLLER-SQQFHSTGGEPLPSVGEFIKAEAERLAPEEWKEDRDNFAVRMAMINTLLKLECCVSGTHTMDDV-----GLGAFGMYTTLPGLDCTFPGGYEGLTDHMMKELPRDIVLYNKPVKCIHWNYTKNGPNTGGTSFPVTIECVNGETFAADHVIVTVPLGYMKKHQNTFLSPSFPLHKLHSIQRMGFGTNNKIFVEFEQPFWDEDCELIYLVWEDETHLTDVVSDLKMSWIRKLTGFTVLKPTERFGHVLCGWIAG-QESEYMESLSELEVLQTVTQ-LLRIFTGNPTIMPRKLLRSQWFHEPYSCGSYSYVAKGCSGYDIDNLAEPLPLKGSNSKPLQVLFAGEATHRSFFSTVHGALLSGWREAE 493          

Query:  208 LHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHG-KKGNPIYDI-----LVNIDVPLELGQPIE---NDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVD------PLGGLKLINYLCKDF-KDQIKLKHKVKVIDW-----SKESEV--VKIVTDNDEEFHCKNVIITLPSELLARESIKFL-PKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVI-KNVDPVNEL-IFWQNCSCQNLCA-------EEDNILICHFTSGSQQGSSRF--DVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSVG-------PLH--FAGESVIVELIGTMQGAYISGIEAAKH 1473
            LH++G  NF I E++ + GGRI++ K+   +   G  W+HG    NP++ +     L++ +   E  Q +E   + +  V  + S + I     E V ++ +     + ++     +PE++    L +  +   S ++ ER  L   M +  G  L +L       H   Y        + ++       P G   L++++   F  D + L   VK I+W       +S +  V++  +N E F   +VI+T+P   L  ++   L P LP  KL A + +      ++  +F   FW  + + IQ+I +   P+ E     Q    + +         E+   ++C F +G +   S F   + ++E+   +T  ++    +    P   +  T W SE ++ GS+S V+ G +  DI+ L + +        PL   FAGE+       T  GA +SG   A+ 
Sbjct:   66 LHERGFRNFRILEATGRSGGRIRSRKYAKGLVEIGAQWIHGPSPSNPVFQLSTQYNLLSSEALSEENQLVELEGHPMFSVIYSSSGKQINRGVGENVVEMFSSWLQKSREFTKGGCNPEESVGSFLRQ--EICNSYSNWERDSLELKMALLSG--LFKLECCISGTHSMDYVALSSCGEYEMLPGLDCTFPRGYESLVDHIKASFPSDNVLLNKPVKTINWKGSFSGSDSRIYPVQVECENGETFVADHVILTVPLGFLKEKATDLLSPPLPSYKLQAIQNLGFGTNNKILLEFEKPFWEPECYAIQLIWEGESPLTETKTNLQQDWVKKIPGFVVLQPPEQLGHVLCAFIAGKE---SEFMETLSEDEILSAMTILLRNCTGNPNLPPPISILCTRWHSEPYTRGSYSYVAVGSTGQDIDMLAQPLPEEQECAMPLQVLFAGEATHRNFYSTTHGALLSGWREAER 525          

Query:  226 HNFAI----FESSYKIGGRIQTVK-FGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVN-KLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFES-----MTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNF---RIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCA-------EEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFSG-SFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            HNF I     E+  +IGGR+   K F G I   G   V+G   NPI  +   I + +   + +      + +     D     ++R++     +L+ V E   DK  + +    D + E    F        TD+E  VL      +E   G+ LH++SA +       +D  E    F     +   G   +I+ L +     I+L   ++ +D++  S+ V+I   + + F  +  ++T+P  LL + +I+F P LP +K+ A   +      ++  +FP RFW  K        ++ P        NC+ + L         E  + ++    +G    S + ++E +++ +     ++ +F           F+THW  + ++  ++S V  G S    + L + + G + FAGE+       T+ GAY+SG+  A
Sbjct:  401 HNFGIKVTVVEARDRIGGRVWDEKSFKGVIVGKGAQIVNGCINNPIAIMCEQIGIKM---RKLREKCDLIEEGGRLTD--PAIDKRMDFHFNAVLDVVAEWRKDKTQNQDAPLGDKIQEICKAFTQESGIQFTDVEEKVLQFHLGNLEYACGSNLHKVSARS-------WDHNEFFAQFAGDHTMLGAGYSMVIDKLAEGL--DIRLNTPIRNVDYT--SQEVRITAADGQTFTAQKALVTVPLALLQKGAIQFNPLLPEKKVKAIHSLGAGVIEKIALQFPYRFWDNKIQGADFFGHIPP--------NCNKRGLFGVFYDMDPEGKHAVLMSVITGDAVTSIQ-ELEDKQVVKQCMVILREVFKEQEVPAPIKYFVTHWAKDPWAHMAYSFVKTGGSGEAYDILAEDIQGKIFFAGEATNRHFPQTVSGAYLSGVREA 815          

Query:  202 RYLHKKGQHNFAIFESSYKIGGRIQTVK-FGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVN-KLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFES-----MTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLK---LINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCA-------EEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFSG-SFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            +YL  K  HN  + E+  +IGGR+   K F G I   G   V+G   NPI  +   I + +   + +      + +     D     ++R++     +L+ V E   DK  + +    D + E    F        TD+E  VL      +E   G+ LH++SA +       +D  E    F     + G     +I+ L +     I+L   V        S+ V+I   + + F  +  ++T+P  LL + +I+F P LP +K+ A   +      ++  +FP RFW  K        ++ P        NC+ + L         E  + ++    +G    S + ++E +++ +     ++ +F           F+THW  + ++  ++S V  G S    + L + + G + FAGE+       T+ GAY+SG+  A
Sbjct:  346 QYLLPKEYHNVTVVEARDRIGGRVWDEKSFKGVIVGKGAQIVNGCINNPIAIMCEQIGIKM---RKLREKCDLIEEGGRLTD--PAIDKRMDFHFNAVLDVVAEWRKDKTQNQDAPLGDKIQEICKAFTQESGIQFTDVEEKVLQFHLGNLEYACGSNLHKVSARS-------WDHNEFFAQFAGDHTMLGAGYSMVIDKLAEGL--DIRLNTPVNYT-----SQEVRITAADGQTFTAQKALVTVPLALLQKGAIQFNPLLPEKKVKAIHSLGAGVIEKIALQFPYRFWDNKIQGADFFGHIPP--------NCNKRGLFGVFYDMDPEGKHAVLMSVITGDAVTSIQ-ELEDKQVVKQCMVILREVFKEQEVPAPIKYFVTHWAKDPWAHMAYSFVKTGGSGEAYDILAEDIQGKIFFAGEATNRHFPQTVSGAYLSGVREA 761          

Query:  226 HNFAI----FESSYKIGGRIQTVK-FGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVN-KLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFES-----MTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLK---LINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCA-------EEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFSG-SFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            HNF I     E+  +IGGR+   K F G I   G   V+G   NPI  +   I + +   + +      + +     D     ++R++     +L+ V E   DK  + +    D + E    F        TD+E  VL      +E   G+ LH++SA +       +D  E    F     + G     +I+ L +     I+L   V        S+ V+I   + + F  +  ++T+P  LL + +I+F P LP +K+ A   +      ++  +FP RFW  K        ++ P        NC+ + L         E  + ++    +G    S + ++E +++ +     ++ +F           F+THW  + ++  ++S V  G S    + L + + G + FAGE+       T+ GAY+SG+  A
Sbjct:  375 HNFGIKVTVVEARDRIGGRVWDEKSFKGVIVGKGAQIVNGCINNPIAIMCEQIGIKM---RKLREKCDLIEEGGRLTD--PAIDKRMDFHFNAVLDVVAEWRKDKTQNQDAPLGDKIQEICKAFTQESGIQFTDVEEKVLQFHLGNLEYACGSNLHKVSARS-------WDHNEFFAQFAGDHTMLGAGYSMVIDKLAEGL--DIRLNTPVNYT-----SQEVRITAADGQTFTAQKALVTVPLALLQKGAIQFNPLLPEKKVKAIHSLGAGVIEKIALQFPYRFWDNKIQGADFFGHIPP--------NCNKRGLFGVFYDMDPEGKHAVLMSVITGDAVTSIQ-ELEDKQVVKQCMVILREVFKEQEVPAPIKYFVTHWAKDPWAHMAYSFVKTGGSGEAYDILAEDIQGKIFFAGEATNRHFPQTVSGAYLSGVREA 786          

Query:  226 HNFAI----FESSYKIGGRIQTVK-FGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVN-KLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFES-----MTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNF---RIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCA-------EEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFSG-SFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            HNF I     E+  +IGGR+   K F G I   G   V+G   NPI  +   I + +   + +      + +     D     ++R++     +L+ V E   DK  + +    D + E    F        TD+E  VL      +E   G+ LH++SA +       +D  E    F     +   G   +I+ L +     I+L   V        S+ V+I   + + F  +  ++T+P  LL + +I+F P LP +K+ A   +      ++  +FP RFW  K        ++ P        NC+ + L         E  + ++    +G    S + ++E +++ +     ++ +F           F+THW  + ++  ++S V  G S    + L + + G + FAGE+       T+ GAY+SG+  A
Sbjct:  387 HNFGIKVTVVEARDRIGGRVWDEKSFKGVIVGKGAQIVNGCINNPIAIMCEQIGIKM---RKLREKCDLIEEGGRLTD--PAIDKRMDFHFNAVLDVVAEWRKDKTQNQDAPLGDKIQEICKAFTQESGIQFTDVEEKVLQFHLGNLEYACGSNLHKVSARS-------WDHNEFFAQFAGDHTMLGAGYSMVIDKLAEGL--DIRLNTPVNYT-----SQEVRITAADGQTFTAQKALVTVPLALLQKGAIQFNPLLPEKKVKAIHSLGAGVIEKIALQFPYRFWDNKIQGADFFGHIPP--------NCNKRGLFGVFYDMDPEGKHAVLMSVITGDAVTSIQ-ELEDKQVVKQCMVILREVFKEQEVPAPIKYFVTHWAKDPWAHMAYSFVKTGGSGEAYDILAEDIQGKIFFAGEATNRHFPQTVSGAYLSGVREA 798          

Query:  226 HNFA----IFESSYKIGGRIQTVK-FGGKIFSSGPGWVHGKKGNPIYDILVNIDVPL-ELGQPIENDILFVWDTDSCQDITELFNERVNK-----LKNILEYVNEKYYDKVI--------DPEKNFKDLLMESSDYFESMTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNE-----LIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSE---RFSGSFSKVSPGISKVDI--EELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            HNF     + E+  +IGGR+   K F G +   GP  V+G   NP+  +   + + + +LG+            D  Q+   + +  V+K        +L+ V+E   DK +          E+ ++  + ES   F   ++LE  VL    + +E   G+ LH++SA +   H+E +    G  +  ++ P G   +I  L +     I+LK  V+ ID++ +   V++ T +      + V++T+P  +L R +I+F P L  +K+ A   +      ++  +FP RFW  K        +V P         +F+   S Q++        +    +G    S R   +K+ L + +   ++ +F           F+T W +E   + + SF K        DI  EE+    G + FAGE+       T+ GAY+SG+  A
Sbjct:  408 HNFGMKVTVLEAKDRIGGRVWDDKSFKGVVVGRGPQIVNGCINNPVALMCEQLGISMRKLGE----------RCDLIQEGGRITDPTVDKRMDFHFNALLDVVSEWRKDKTLLQDVPLGEKIEEIYRAFVKESGIQF---SELEGQVLQFHLSNLEYACGSSLHQVSARS-WDHNEFFAQFAG--DHTLLTP-GYSTIIEKLAEGL--DIRLKSPVQSIDYTGDE--VQVTTTDGMGHSAQKVLVTVPLAILQRGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASQRGLFAVFYDMDSQQSV--------LMSVITGEAVASLRTMDDKQVLQQCMG-ILRELFKEQEIPEPTKYFVTRWSTEPWIQMAYSFVKTFGSGEAYDIIAEEI---QGTVFFAGEATNRHFPQTVTGAYLSGVREA 820          

Query:  229 NFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILE-----------YVNEKY---------YDKVIDPEKNFKDLLME-----SSDYFESMTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKES-EVVKIVTDNDEE---FHCKNVIITLPSELLARE--SIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFW-PEKEWLIQVIKNVDPVNEL-IFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSVGP-------------LHFAGESVIVELIGTMQGAYISGIEAA 1467
            +  + E+  ++GGR+ T + G  +   G   V G  GNP+   +V+  V +EL +  +   L+  +  +  ++ E   E   + K   E            V  K+         YD++ + +   ++ L E      SD + S  D  R +L   +  +E     PL  LS L     D+ ++F    L  R      G   +     +  D IKL   V+ + ++    EV+ + T +  +   + C  V+ TLP  +L ++  +++F+P LP  K SA + +   N  ++   F   FW P       V        EL +FW       L A     L+    +G  +     ++  + +       +K +F  +         ++ W ++ ++ GS+S V+ G S  D + + + + P             L FAGE  I     T+ GA +SG+  A
Sbjct:  212 DVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPM--AVVSKQVNMELAKIKQKCPLYEANGQAMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRD--RQILDWHFANLEFANATPLSTLS-LKHWDQDDDFEFTGSHLTVR-----NGYSCVPVALAEGLD-IKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLA-----LVAGEAAGIME-----NISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREA 653          

Query:  211 HKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHG-KKGNPIYDILVNIDVPLELGQPIENDIL----------FVWDTDSCQDITELFNERVNKLKNIL----EYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLER---TVLYTCMEI---YRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLIN--YLCKDFKDQIKLKHKVKVIDWS---------KESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFL-PKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVI-KNVDPVNELIF-WQNCSCQNLC------AEEDNILICHFTSGSQQGSSRF--DVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSVG--------PLHFAGESVIVELIGTMQGAYISGIEAA 1467
            H+   H   + E++   GGRI++ +  G +   G  W+HG  + NP++ +     +  E     EN ++           +W +       EL  E       ++    E++NE         E   K++  + + + E   D  +    +L T   I     G    +L ALA      V    + IL        GG + +    L    KD +     VK I W+          E+  V +  ++       +VI+T+P   L      F  P LP +K  A K +      ++F +F   FW      IQV+ ++  P+ +     Q+   + L       + E + ++C F +G +   S F   +  EE+   +T+ ++R+  +     +  +  + W S  ++ GS+S V+ G +  D++ + + +          + FAGE+       T  GA +SG   A
Sbjct:   27 HRAAPH-LRVLEATASAGGRIRSERCFGGVVELGAHWIHGPSQDNPVFQLAAEFGLLGEKELSEENQLVDTGGHVALPSMIWSSSGTSVSLELMTEMARLFYGLIERTREFLNESETPMASVGEFLKKEISQQVASWTEDDEDTRKRKLAILNTFFNIECCVSGTHSMDLVALAPFGEYTVLPGLDCILA-------GGYQGLTDRILASLPKDTVAFDKPVKTIHWNGSFQEAAFPGETFPVLVECEDGARLPAHHVIVTVPLGFLKEHQDTFFEPPLPAKKAEAIKKLGFGTNNKIFLEFEEPFWEPDCQFIQVVWEDTSPLQDTALSLQDTWFKKLIGFLVQPSFESSHVLCGFIAGLE---SEFMETLSDEEVLLSLTQVLRRVTGNPQLPAAKSVRRSQWHSAPYTRGSYSYVAVGSTGDDLDLMAQPLPEDGTGTQLQVLFAGEATHRTFYSTTHGALLSGWREA 486          

Query:  787 IKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCA-----EEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSE---RFSGSFSKVSPGISKVDI--EELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            I+LK  V+ ID++ +   V++ T +      + V++T+P  +L R +I+F P L  +K+ A   +      ++  +FP RFW  K        +V P        + S + L A     +    ++    +G    S R   +K+ L + +   ++ +F           F+T W +E   + + SF K        DI  EE+    G + FAGE+       T+ GAY+SG+  A
Sbjct:  215 IRLKSPVQSIDYTGDE--VQVTTTDGMGHSAQKVLVTVPLAILQRGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPP--------SASQRGLFAVFYDMDSQQSVLMSVITGEAVASLRTMDDKQVLQQCMG-ILRELFKEQEIPEPTKYFVTRWSTEPWIQMAYSFVKTFGSGEAYDIIAEEIQ---GTVFFAGEATNRHFPQTVTGAYLSGVREA 437          

Query:  781 DQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILIC---HFTSGSQQGSSRFDVEK--EELTEIVTESMKRMFPHTYC---APSDVLFITH-----WDSERFSGS--FSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAAKHSL 1479
            D++KL   V  ID + ++ +++  T N E + CK VI  +P  L A+  I F P+LP E+    + +P     +    +   FW +K++                   C C  +  EE  I I        GS      F + +  E L ++  +  KR     Y       + L   H     W  E++SG    +   PGI  +    + + VG ++FAG     +  G M+GA  +G  AA+  L
Sbjct:  236 DKVKLSSPVTYIDQTDDNIIIE--TLNHEHYECKYVISAIPPVLTAK--IHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDY-------------------CGCMIIEDEEAPISITLDDTKPDGSMPAIMGFILARKAERLAKLHKDIRKRKICELYAKVLGSQEALSPVHYEEKNWCEEQYSGGCYTAYFPPGIMTLYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVL 460          

Query:  208 LHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKG---NPIYDILVNIDVPLE--------LGQPIENDILFVWDTDSCQDITELFN---ERVNKLKNIL-------------EYVNEKYYDKVIDPEKNFKDLLMESSDYFE--SMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGG--LKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEI-VTESMKRMFPHTYCAPSDVLFITHWDSERF-SGSFSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAAK 1470
            L + G  +  I E++  IGGR+    F G     G  WV G  G   NPI+ I VN  + L         L Q +  +   V+D D  Q   EL +   E   KL   L             + +NE   +    P     D      ++ E   +T L+ TV           PL   S       D+VY   +      +V  L G  LK  +   K    +++L   V+ I +S     VK  T+++  +    V+++    +L  + I+F PKLP  K+ A        Y ++F KFP +FWPE +     +           WQ    Q   A   N+L+   T    + S R + + +E T+  + + +++MFP      +  + +  W S+RF  G+FS    G+++ + ++L   VG ++F GE       G + GAY+SGI++A+
Sbjct:   51 LSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNGGKMNPIWPI-VNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQNTV-----------PLATFSDFG----DDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVK--TEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDA---NVLLVTVTD---EESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAE 480          

Query:  208 LHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKG---NPIYDILVNIDVPLE--------LGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYD--KVIDPEKNFKDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKD----------QIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEI-VTESMKRMFPHTYCAPSDVLFITHWDSERF-SGSFSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEA 1464
            L + G  +  I E++  IGGR+   +F G     G  WV G  G   NPI+ I VN  + L         L Q +  D     D    Q   +L +E     +N+   ++    D   ++  ++    L    S   + + D   T  Y   E  R   L     L         DF  G  N+ + D  G   ++ YL   + +          +++L   V+ I +S     VK  T+++  +    V+++    +L  + I+F P+LP  K+ A        Y ++F KFP +FWPE       +           WQ    Q   A   N+L+   T    + S R + + +  T+  + E ++ MFP      +  + +  W S+RF  GSFS    G+S+ + ++L   VG ++F GE       G + GAY++GI A
Sbjct:   49 LSEAGITDILILEATDHIGGRMHKQRFAGVNVEIGANWVEGVNGEKMNPIWPI-VNSTLKLRNFLSDFDSLAQNVYKDGGLC-DAAYVQKRIDLADEADKSGENLSATLHPSGRDDMSILSMQRLNNHLPNGPSSPVDMVVDY-FTYDYEFAEPPRVTSLRNTVPLPTFT-----DF--GDDNYFVADQRGYEAVVYYLAGQYLEADKSGNIVDARLQLNKVVREISYSSTGVTVK--TEDNSTYQADYVMVSASLGVLQSDLIQFKPQLPSWKILAIYQFDMAVYTKIFVKFPKKFWPEGAGREFFLYASTRRGYYGVWQEFEKQYPDA---NVLLVTVTD---EESRRIEQQPDSQTKAEIMEVVRSMFPDEDVPDATDILVPRWWSDRFFQGSFSNWPIGVSRYEHDQLRAPVGRVYFTGEHTSERYNGYVHGAYLAGIYA 474          

Query:  214 KKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWV---HGKKGNPIYDILVNIDVPLE--------LGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKV-IDPEKNFKDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQH--DEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKD-QIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEI-VTESMKRMFPHTYCAPSDVLFITHWDSERF-SGSFSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAAK 1470
            + G  +  I E++ +IGGR+    F G     G  WV   +G+K NPI+ I VN  + L         L Q +  D     D    Q   +  +E     +N+   ++    D + I   +   D L         M     T  Y   E  R   L     L       D+ Y   +      +V  L G  L      +  D ++KL   V+ I +S     VK  T+++  +    V+++    +L  + I+F P+LP  K+ A        Y ++F KFP +FWPE       +           WQ    Q   A   N+L+   T    + S R + + +  T+  + E ++ MFP      +  + +  W S+RF  GSFS    G+S+ + ++L   VG ++F GE       G + GAY++GI++A+
Sbjct:   51 EAGIADVLILEATDRIGGRMHKQSFAGVNVEIGANWVEGVNGEKKNPIWPI-VNSTLKLRSFRSDFDSLAQNVYKDGGLC-DEAYVQKRMDRADEVDKSGENLSATLHPSGRDDMSILSMQRLNDHLPNGPSSPVDMAVDYFTYDYEFAEPPRVTSLQNTVPLPTFTDFGDDTYFVADQRGYESVVHHLAGQYLNADKSGNIADARLKLNKVVREISYSSTGVTVK--TEDNSTYQADYVMVSASLGVLQSDLIQFKPQLPSWKILAIYQFDMAVYTKIFVKFPKKFWPEGAGREFFLYASTRRGYYGVWQEFEKQYPDA---NVLLVTVT---DEESRRIEQQPDSQTKAEIMEVVRCMFPDEDVPDATDILVPRWWSDRFFRGSFSNWPIGVSRYEYDQLRAPVGRVYFTGEHTSERYNGYVHGAYLAGIDSAE 476          

Query:  238 IFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQ---PI--ENDILFVWDTDSCQDITEL-FNERVNKLKNILEYVNEKYYDKV---IDPEKNFKDLLMESSDYFESMTDLERTVLYT------------CMEIYRGAPLHELSALAEIQHDEVYDFEEGILNF---RIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDE----EFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWP-------EKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTES---------MKRMFPHTYCAPSDVLFITHWDSERFSGSFSKVSPGISKVDI--EELCKSVG-PLHFAGESVIVELIGTMQGAYISGIEAA 1467
            +FE+  + GGR+   +  G     G   + G   NPI  +   I +         P+  EN   F  +     D  +L +N  ++ ++N  +Y +++ +  V   +   ++F ++  + S    S  DL+   LYT             +E   G  +  LSA       + YD  E   NF     V   G  ++I++L       I+L   VK IDW ++   VKI  +N E    EF  K VI T  S L +  S  F+P LPIEK  A   +      ++  KF  RFW          E+  +V       +    + + S ++   E+  +L+ + T+           E   L  ++TES         +++MFP     P   + ++HW ++RF G      P  S  D    +L KS+   L+FAGE  I     TM GAYISG+  A
Sbjct:  379 LFEAKDRFGGRMMDDQSLGVSVGKGAQIIVGNINNPITLLCEQIGIKYRNSNFFCPLIDENGRCFTLERKELDDQVDLHYNNVLDAIRN--KYQSDRNFPDVPLEVTNFRHFTEMFSKMSSGLLSAADLDS--LYTPEFEKLLDFHLGNLEFSCGTHVSNLSA-------KDYDHNEKFGNFAGEHAVITDGAQRIIDFLATGL--DIRLNCPVKCIDWGRDDRKVKIFFENAEQAAEEFD-KVVITTSLSVLKSNHSKMFVPPLPIEKQKAIDDLGAGLIEKIAVKFDRRFWDTVDADGLRTEYFGKVSDCKTDRSLFNIFYDFSGKDPNGEDTFVLMSYVTA-----------EHVNLVNVLTESEVADKFCATLRKMFPSAVINPLGHM-MSHWGADRFVGMSYTFVPFGSDGDATYNQLKKSIDEKLYFAGEHTIAAEPQTMAGAYISGLREA 809          

Query:  202 RYLHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGW---VHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKY--------YDKVIDPE-KNFKDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVY-DFEEGILNFRIVDPLGGLKLINYLCKDF---------KDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESM---KRMFPHTYCAPSDVLFITHWDSERFSGSFSKVSPGISKVDIEELCKS-VGPLHFAGESVIVELIGTMQGAYISGIEAAKHSL*E 1485
            + L + G  +  I E++ +IGGRI    FG      G GW   V GK+ NP                        VW+  S  ++   F++  N   NI +   + +        Y K +D      K L  + S     + +   +   T +E+     LH+   +AE++    Y DF E    F + D  G   L+  + ++F           ++KL   V+ +  S+   VVK  T++   +    VI++    +L  + + F P LP  K  A +    + Y ++F KFP  FWP        I   +      FWQ+           NIL+   T+   + S R + + ++  E + E+M   + MF  T    +D+L    W++    GS+S   P IS   + +  K+ VG + F GE    +  G + G Y++GI+ +K  L E
Sbjct:   20 KVLVENGVEDVLILEATDRIGGRIHKQNFGDVPVELGAGWIAGVGGKESNP------------------------VWELASRFNLRTCFSDYTNARFNIYDRSGKIFPTGIASDSYKKAVDSAILKLKSLEAQCSG---QVAEEAPSSPKTPIELAIDFILHDFE-MAEVEPISTYVDFGE--REFLVADERGYECLLYKMAEEFLVTSHGNILDYRLKLNQVVREVQQSRNGVVVK--TEDGSVYEANYVIVSASIGVLQSDLLSFQPLLPRWKTEAIQKCDVMVYTKIFLKFPQCFWPCGPGQEFFIYAHEQRGYFTFWQHMEN---AYPGSNILVVTLTN---EQSKRVEAQSDQ--ETMKEAMSVLRDMFGATIPYATDILVPRWWNNRFQRGSYSNY-PMISDNQLLQNIKAPVGRIFFTGEHTSEKFSGYVHGGYLAGIDTSKSLLEE 432          

Query:  202 RYLHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKD----QIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQV--IKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFD-VEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSER-FSGSFSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAAKHSL 1479
            + L   G  +F I E S +IGGR++ V FGG    +G  WVHG +GNP++++   +D    L   +++    V   D   D+TE    R   L+   ++ +     K+ +   +    +      ++++  +++ V Y   +   GA     S L     + + DF++    + + D  G   ++  + + F D    +++    V  I WS +  VV+  T +  E+  +  + T    +L  + I F+P+LP  KL     V   +Y ++F KFP +FW  KE++      +   P+ + +  + C          NIL    T    + S R + +    +   + E ++ ++      P D+ F++ W  +  F G+F+++  G  +   E+    VG L+F GE+     +G + G  ++G++ AK  L
Sbjct:   42 KTLQDNGVQDFIILEGSDRIGGRMRLVDFGGVKIEAGANWVHGIRGNPVWELAQGLD----LKGKVQDVAKMVVRDDDGADVTEHAVSRFADLQRARKHAHAMLERKISEDGNDTSIRVALRLAGWKAIAPVDKVVEYFSFDFQNGATPDVTSLLQNEDEETLVDFDD--KEYFVTDQRGFGFIVEEMARTFLDKQDPRLQFNKCVDEIKWSNQGVVVR--TSDGSEYSAEYALTTFSLGVLQSDHISFVPELPDWKLEEIYQVEMCHYTKIFLKFPFKFWDGKEYIFHAHPKRGYYPIMQDMEAEGCHPPGT-----NILAVTVTG---EESKRVEGLPNSTVASEIMEVLRNLYGEDVPTPVDI-FVSRWSQDPLFLGAFTRIPTGAFRDGTEKYKAPVGRLYFGGEAFHERYMGFVHGGLLAGVDKAKDIL 458          

Query:  238 IFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLERTVLY----TCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKE-SEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNV--DPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTES---MKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSVG-PLHFAGESVIVELIGTMQGAYISGIEAAKHSL 1479
            + E+  +IGGRI + +  G     G  W+HG  GNPI  +     V   L Q    D+   WD   C+      +ER+N  ++  E + +         + + +D L ++        D     L+    T + +  GA +  LS     +H   +  +E +     V P G  +L+  L       ++L+H V+ + WS + S+ V+I ++    F     IITLP  +LA  ++ F P LP  K  A   +      ++  +FP  FWPE    +Q++  V  +PV  L         +L      +L+     G Q G++    E++   EI+  +   ++R F      P   L +T W  + +S GS+S V PG S V  + +   +G  L FAGE+       TM GAY+SG+  A+  L
Sbjct:   33 VLEARARIGGRIHSDRSLGVAVDLGASWIHGVTGNPITALARAHGVRAALAQHAAFDL---WDAAGCR---LALDERLNSFRDFQEVLAQATE------QASRQDSLAQALARVAPAMDAREQRLFEGWKTWLALVMGADVAALSG----RH---WSDDEELPGPDYVIPGGCDQLLPALADGV--DVRLEHAVRGVRWSDDPSQGVEIDSERG-SFRAARAIITLPLGVLASGAVHFEPALPPAKQRAIAGLGMGTLDKIAMRFPAPFWPEHLSTLQMLARVPDEPVGFL---------SLLPHGAPVLV-----GFQAGAAAVTQERQSDDEIIARALGVLRRSFGGAVAEPESAL-VTRWHEDPWSRGSYSHVPPGASSVLYKRMATPLGQALLFAGEATSRAYPATMHGAYLSGLREAERVL 421          

Query:  202 RYLHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKK-----GNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEI-QHDEVYDFEEGIL---NFRIVDPLGGLKLINYLCKDF--KDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLI--QVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEI-----VTESMKRMFPH-TYCAPSDVLFITHWDSERFSGSFSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAAKHSL 1479
            R LH+ G  NF I E+  ++GGR+ T  FGGK    G  W+ G +      NPI+ +    +V  +L     +   F  DT    D  ++F+   +   ++      +    ++D        L+++    +  TD ER   Y   +        E S +A    ++  Y+ ++G     N   +D  G   LI    +DF    QI+L   VK I +SK    V +   N +       + T    +L  + +KF P+LP  K  A + +    + ++F KFP +FW + E  I     +   PV     WQ+    N       IL    T         F +  E L++      V E ++ M+P+ T   PS+  F     +  F GS+S   P +S   I+ L  +VG L+F+GE+   +  G +QGAY  G  AA + L
Sbjct:   51 RTLHQSGIDNFVIVEARDELGGRMMTTTFGGKTIEQGANWIQGTQTGKGPANPIFTLAKKHNVSTQLNDWSGSVTTF--DTTGAVDWLDVFDASGDDFDDMTVAAGARVDQNLVDLSARTGYSLIKA----KPKTDQERAAEYYQYDWEYAQTPEESSLIASAWGNNFTYNTDQGGFSEDNLMSIDQRGFKALIQLEAQDFLTPSQIQLNSVVKNITYSKSG--VTVTLTNGKTLTGDYALCTFSLGVLQNDDVKFQPELPDFKQEAIQSMVMGTFTKIFLKFPKKFWFDTEMGIFADSTRGRYPV-----WQSLDHPNFFPGS-GILFVTVTG-------DFSIRIEALSDQKVQAEVMEVVRMMYPNITVPEPSEFFFPRWHTNTLFRGSYSNWPPALSSQHIDNLRANVGRLYFSGEATSRKYFGFLQGAYFEGQTAANNIL 474          

Query:  202 RYLHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKD------LLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDF----KDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELT-EIVTESMKRMFPHTYCAPSDVLFITHWDSER-FSGSFSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAAKH 1473
            + L   G ++F I E + +IGGR++  KF G     G  W+ G KGNPI + L  I     L   +EN   FV   ++  + TE       + K  L    E   +K+ID  +          + +  +D+  S  + E    Y   +     P   +S  A I +  +     G   F + DP G + +++ L   F      +++L   V+ I WS+    V +VTDN + ++    ++T    +L    + F P+LP  KL A   +  V Y ++F KFP++FW ++E+++   +       +   QN    +   +  NIL+   T   ++ S R   +  E T E + E ++ M+      P D+ +   W  +R F GS++ +  GIS+ D   L   V  + FAGE+      G + G Y++G+E AK+
Sbjct:   46 KTLSDMGINDFVILEGTERIGGRMRKTKFQGTTIEMGANWIQGVKGNPI-ERLKEI---CGLQGKVENRS-FVIRNETGNNTTE-------RGKMALLKHEEDVLNKMIDMRRQMGGADISARVGLRLTDWLPSNPE-EMATEYFEYDFEYAVPPKYVSLRAGIANHGIIH-SVGGEQFFVTDPRGYVHIVDCLAGMFLEPGDSRLQLNTTVEEIKWSENG--VNVVTDNGDVYNADYALLTFSIGVLQSGLVTFTPQLPEWKLEAIFKLSMVIYTKIFIKFPSKFWDDEEYILYASQRRGYYTMM---QNLEADSRLPKGTNILLITVT---EEESVRLAYQSNEKTQEEIMEVLRGMYGKNIPEPIDIYY-PRWGLDRYFFGSWANLPIGISRQDYVNLQAPVKQVFFAGEATHELYNGYVHGGYLTGVEQAKN 458          

Query:  202 RYLHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKK-----GNPIYDILVNIDVPLELGQPIEND---ILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNF---------KDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGIL---NFRIVDPLGGLKLINYLCKDF--KDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLI--QVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEEL--TEIVTESM---KRMFPH-TYCAPSDVLFITHWDSERFSGSFSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAAK 1470
            R LH+ G  ++AI E+  ++GGR+QT +FGGK+   GP W+ G +      NPI+ +     +  +      ND    +  +D     D  ++FN+  +    +     E+    ++D              KD    + +Y++   D E          Y   P       +   ++  YD ++G     N   +D  G   LI    ++F   +Q+     VK I  S  S  V +   N ++      I+T    +L  + +KF P LP  K  A + +    Y ++F KFP +FW + E  I     +   PV     WQ+    N       + +          +  F V  E L  +++ +E M   + MFP+ T   P D  F     +  F GS+S   P  +   ++ L  +VG L+FAGE+   +  G + GAY  G+E A+
Sbjct:  956 RTLHENGIEDYAIVEARSELGGRMQTKEFGGKVIEQGPNWIQGTQEGNGPANPIFTLANKHKIKTQF-----NDWFGSVSTYDASGAVDFLDVFNDSSDDFDTMTVLGGERVDQSLVDLSARTGYSILGVKPKDAQARACEYYQ--YDWE----------YAQTPEESSLIASSWGNNFTYDTDQGGFSDDNRMSIDQRGFKTLIQLEAQEFLQPNQVFFNSTVKSISHSNSS--VTVTLTNGKKLTADTAIVTFSLGVLQNDDVKFEPALPAFKQEAIQSMVMATYTKIFLKFPQKFWFDTEMAIFADSERGRYPV-----WQSLDHPNFFPGSGIVFVTV--------TGDFSVRIEGLPDSQVKSEVMGVVRTMFPNVTVPEPLDFFFPRWHSNPLFRGSYSNWPPSFTSQHLDNLRANVGKLYFAGEATSRKYFGFLHGAYFEGLEIAQ 1376          

Query:  202 RYLHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKG-----NPIYDIL----VNIDVPLELGQPIENDILFVWD--TDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDL--ERTVLYTCMEIYRG----APLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDF--KDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESM---KRMFPH-TYCAPSDVLFITHWDSERFSGSFSKVSPGISKVDIEELCKSVGPLHFAGES 1407
            R L + G  +FAI E+ +++GGRIQT +FGGK+   G  W+ G +      NPI+ +     +N       G   E  I FV D  T       +  +E    ++N  E++ E   D+V    ++ +D+   S+    SM  L  E      C E Y+     A   E S+LA       + F +   N   +D  G   LI    ++F   +Q+     VK I +S  S +V +   N +       I+T    +L  + + F P LP  K  A + +    Y ++F  FP +FW + E  + +I           WQ+    N       IL          G S   VE     ++ +E M   + MFP+ T   P D  F     +  F G+FS  +P  +    ++L  +VG L+FA E+
Sbjct:  501 RTLRRNGIEDFAIVEARHELGGRIQTKEFGGKVVEQGANWIQGTQQGDGPVNPIFTLANKHKINTQYNDWFGSVFEL-IRFVVDEATFDTSGAVDFLDELDASVRN-YEWLAELSVDRV---SQSLEDI---SARAGYSMLGLNPENPRAQAC-EYYQYDWEYAQAPEQSSLAAAARGSEFGFSDD--NRLSIDQRGFKSLIQLEAQEFLKPNQVFFNSTVKSISYSNSSVIVTLT--NGQNLSGDAAIVTFSLGVLQNDDVAFEPPLPDFKQEAIQRMTMATYTKIFLHFPQKFWFDTE--MAMIFADSERGRYPVWQSLDHPNFLPGS-GILFTTVI-----GDSAVRVEGLPDNQVKSEVMSVVRTMFPNVTVPEPLDFFFPRWHSNPLFRGAFSNQTPSFTSRHFDDLRANVGKLYFAREA 904          

Query:  202 RYLHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKK-----GNPIYDILVNIDVPLELGQPIEN----------DILFVWDTDSC--QDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGIL---NFRIVDPLGGLKLINYLCKDF--KDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDP-VNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEI-----VTESMKRMFPH-TYCAPSDVLFITHWDSER-FSGSFSKVSPGISKVDIEELCKSVGPLHFAGESV 1410
            R LH+ G  +FAI E+  ++GGR+Q+  FGG++   G  WV G +      NPI+ +     + ++      +          D L   D  S   + +T L   RV +    L+ ++ +    ++  +   KD    + +YF+   D E          Y  +P       +   ++  +D  +G     N   +D  G   LI    ++F   +Q+     VK I  S     V +   N  +   +  IIT    +L  + +KF P LP  K  A + +    Y ++F +FP +FW + E  I      DP       WQ+    N       IL    T        RF +  E L++      V   ++ MFP+ T   P D  F   W+S   F GS+S   P  +   +++L ++VG L+FAGE++
Sbjct:   51 RTLHQNGVDDFAIIEARNELGGRMQSRAFGGRVVEIGANWVEGTQEGEGPANPIFMLANKHGIKMQFSNLFGSISTYDDSGAVDFLDALDASSADFERMTALAGARVEQG---LDDLSSRAGYSIVGAKP--KDAHARACEYFQ--YDWE----------YAQSPEESSLIASSWNNNYTFDVSQGGFSDDNRMSIDQRGFKTLIQSEAQEFLKPNQVFFNSTVKTIAHSNSG--VTVTLTNGRKLSGETAIITFSLGVLQNDDVKFEPILPDYKQEAIQSMSMGTYTKIFLQFPNKFWFDTEMAI----FADPERGRYPIWQSLDHPNFMPGS-GILFATVT-------GRFALRIEALSDDQVKNEVMGVLQSMFPNVTIPEPLD-FFFPRWNSNPLFRGSYSNWPPSFTSQHLDDLRENVGRLYFAGEAM 451          

Query:  208 LHKKGQHNFAIFESSYKIGGRIQTVK-FGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFE---------SMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHK-VKVIDW-----SKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIK-FLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIF--------WQNCSCQNLCA----EEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDV--LFITHWDSE-RFSGSFSKVSPGISKVDIEELCKSVGPLH------------FAGESVIVELIGTMQGAYISGIEAAKH 1473
            L + G     + E++ ++GGR+ T K F   I   G  W+HG+KGNP++ +    ++  E     + D  F    +  + +++   E+V  L    E +  K  D  ID  + ++ L +   DY +         S  D  R   +             L  ++  Q  E  + +    N   + P G   L++YL KD    I L +K VK I W        +  VK++ ++DE F   +VI+T+   +L +++   F P LP  KL+A + +      ++F  F  RFWPE    IQ++ N  P ++ ++        W+    + +C          ++C + +G +       +E  + +E+    ++ +   T  +  DV  + I+ W  + R  GS+S V  G++  + ++      PL             FAGE+       T  GAY+SGI  A+ 
Sbjct:   29 LVQAGFQQVKVLEANGRVGGRVCTTKPFTRNIIELGANWIHGQKGNPLFQLAKKNNLLSEEADEDDLDDYFF--KEGGKQLSDKLGEKVTAL---FEKLISKASDSKID--RKYRSLSL--GDYLDAAFAESSLASSGDGPRIFEWCKRNECTNEAASSLFEVSAYQLSEYIELDGEFYN--CLGPGGYQALLDYLMKDLPSGIILNNKAVKSIQWDLKPQGGSNHPVKLICEDDEIFEADHVIVTVSLGVLKQKAATMFEPSLPQSKLTAIEQLGFGTVNKIFLCFNERFWPEDCEGIQLVWNEGPEDKSVYTSHSEGEAWKETWYKKICGFDSVARHPTVLCGWIAGREA----LHMETLQDSEVKDTCLRLLRSFTGWSVPDVSKVLISRWGHDSRVLGSYSSVPKGVNGFEKQKELGEPLPLQRKASDSKPLQVLFAGEATHENFYATTHGAYLSGIREAQR 479          

Query:  208 LHKKGQHNFAIFESSYKIGGRIQTVK-FGGKIFSSGPGWVHGKKGNPIYDIL---------VNIDVPLELGQPIE-NDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEK------NFKDLLMESSDYFESMTDLERTVLYT----CMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHK-VKVIDWSKESEV-----------VKIVTDNDEEFHCKNVIITLPSELLARES-IKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIF--------WQNCSCQNLCA----EEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDV--LFITHWDSE-RFSGSFSKVSPGISKVDIEELCKSVGPLH------------FAGESVIVELIGTMQGAYISGIEAAK 1470
            L + G  N  I E++ ++GGR+ T + F   I   G  W+HG++GNP++ +          V+    + L + +   D  F       Q   ++  E V+++ ++   +  K ++  ++ +       ++ D     S    S  D +R   +     C +    + L+E+SA ++I +   Y   EG   F  + P G   +++ L KD   +I L +K VK I W  + ++           VK++ ++D  F   +VI+T+   +L +++   F P LP  KL+A + +      ++F  F  RFWPE    IQ++ +  P ++ ++        W+    + +C          ++C + +G +       +E  + +E+    ++ +   T  +  DV  + I+ W  + +  GS++ V   ++ V   E   +  P              FAGE+  V    T  GAY+SG+  A+
Sbjct:   25 LVRAGFQNVQILEANGRVGGRVHTTRPFSQNIIELGANWIHGQEGNPLFQLAKEHGLLVEGVSASKVMCLPRSVTPRDYFFR------QGGRQVSTESVDQVCSLFSKLTSKAFESELEDKHRALSLGSYLDAAFAESPLAAS-EDGQRLFEWCKRSECTD-EASSSLYEVSA-SQIGY---YIALEGGF-FNSLGPGGYQAILDILLKDLPSEIILTNKAVKSIHWDLKEQLQANEKGGLNHPVKLICEDDGVFEADHVIVTVSLGVLKQQAGTLFKPSLPKSKLTAIEQLGFGTVDKIFLCFNERFWPEDCAGIQLVWDEGPEDKSVYTSHSEGEAWKETWYKKICGFDSVARHPTVLCGWITGREA----LHMETLQDSEVGDACVRLLRSFTGWSVPDVSKVLISRWGLDPQVLGSYTFVPHNVNGVKEHEALAAPIPFQNKIPESKPLQVLFAGEATHVNFYTTTHGAYMSGVREAQ 489          

Query:  238 IFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYY--DKVIDPEKNFKDLLMESSDYFESMTDLE---RTVLYTCMEIYRGAPLHELSAL----AEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFW----------------PEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFSG-SFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            + ES  +IGGR+   K  G     G   V+G   NPI  +   + V                              +++KL++  + + E  +  D  ID   +F         +F ++ D+    R      M+   G  + E+       + IQ  E+   EE +L F + +       + Y C    DQ      V+ ID+S    +V + T    +F  + V++T P  LL +  I+F P LP  KL A   +      ++  +FP RFW                PEK  L  V  ++ P         C   ++   E   L+ +             +E++ + ++    ++ +F           F+THW  + +S  S+S V  G S    + + + V G + FAGE+       T+ GAY+SG+  A
Sbjct:  335 VLESRDRIGGRVWDDKSLGVTVGRGAQIVNGCVNNPIALMCEQLGV------------------------------KMHKLRDRCDLIQEGGHITDPAIDKRMDF---------HFNAILDVVSDWRKDKSQHMDAPLGEKIQEVCKTFLQESTIQFSEL---EEKVLQFHLSN-------LEYACASTLDQ------VQSIDYS--GNLVVVTTSGGTKFTAQKVLVTAPLALLQKNIIQFNPSLPERKLKAIHSLGAGIIEKIALQFPYRFWDSKVKGADYFGHVPPSPEKRGLFSVFYDMTP--------KCVLMSVITGEAVALVKY-------------LEEKAVVQLCMNVLRELFKEQEVPDPLKFFMTHWSKDVWSQMSYSFVKTGGSGEAYDIIAEDVQGKVFFAGEATNRHFPQTVTGAYLSGVREA 693          

Query:  238 IFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVN-KLKNILEYVNEKYYDKVIDPEKNF--------KDLLMESSDYFESMTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPL---GGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNE-----LIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFSG-SFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            + ES  +IGGR+   K  G     G   V+G   NPI  +   + V +     + +    + +     D     ++R++     IL+ V++   DK    +           K  L ES+  F   ++LE  VL    + +E    + L ++SA       + +D  E    F     L   G   L++ L +     I L   V+ ID+S    +V + T    +F  + V++T P  LL +  I+F P LP  KL A   +      ++  +FP RFW  K        +V P  E      +F+      ++  +    ++    +G      ++ +E++ + ++    ++ +F           F+THW  + +S  S+S V  G S    + + + V G + FAGE+       T+ GAY+SG+  A
Sbjct:  426 VLESRDRIGGRVWDDKSLGVTVGRGAQIVNGCVNNPIALMCEQLGVKM---HKLRDRCDLIQEGGHITDPA--IDKRMDFHFNAILDVVSDWRKDKSQHMDAPLGEKIQEVCKTFLQESTIQF---SELEEKVLQFHLSNLEYACASTLDQVSA-------QSWDHNEFFAQFSGDHTLLTEGYSTLLHKLAQGL--DIHLNSPVQSIDYS--GNLVVVTTSGGTKFTAQKVLVTAPLALLQKNIIQFNPSLPERKLKAIHSLGAGIIEKIALQFPYRFWDSKVKGADYFGHVPPSPEKRGLFSVFY------DMTPKGGQCVLMSVITGEAVALVKY-LEEKAVVQLCMNVLRELFKEQEVPDPLKFFMTHWSKDVWSQMSYSFVKTGGSGEAYDIIAEDVQGKVFFAGEATNRHFPQTVTGAYLSGVREA 831          

Query:  781 DQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQ--GSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITH----WDSERFSGS--FSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            + ++L   V  I W  E + VK+ T +     CK VI+T P  + A+  I++ P LP+E+    + +P  +  +    +P+ FW +K +  +++    P  +  F       +      +  +  F +G Q    +SR   E EE  + V  S+ +     Y  P    +I +    W  E ++G    + + PG+       L K  G +H+AG     +  G + GA  +G  AA
Sbjct:  237 ENVRLGDAVTAI-WQSEEDGVKVKTASGA-VSCKAVIVTCPPHMAAQ--IQYQPPLPLERQRLTQCMPVGHMTKFIITYPSAFWKQKGFSGEIVAR--PGEDCPF---AVTFDASTPRGSPALVGFIAGVQACYWNSR---EMEERRDAVVSSLAK-----YLGPEATTYIHYQEKDWSKEEYNGGCPVNVMVPGVLTYYHPALRKPCGRIHWAGTETATQWCGYLSGAVQAGRRAA 456          

Query:  241 FESSYKIGGRIQTVK--FGGKIFSSGPGWVHGKKGNPIYDILVN---IDVPLELGQPIENDILFVWDTDS---------CQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFE---SMTDLERTVLYTCMEIY----RGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDF-KDQIKLKHKVKVIDWSKESEV-----------VKIVTDNDEEFHCKNVIITLP-SELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELI--------FWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSER-FSGSFSKVSPGI-SKVDIEELCKSVGPLH---------FAGESVIVELIGTMQGAYISGIEAAKHSL 1479
             E+  + GGR+ T +    G     G  W+HG+ GNP+Y +      +      GQ  + D  F    +          C+  +E+  +   +   +                ++  D L E   +F    S  +  + V   C  I       + ++E + L+E+ H   Y   EG   F  + P G   +++ L        +     V  I W   +E            V++V ++  EFH  +VI+T+    L A  +  F P LP  KL A + +      ++F +F + FWP+    +Q + N  P +  I        +++  +  N  A   N+L C + +G +  +   D  K  +   +   + R F     +    + +T W+ +R F G+++ +  G+ ++ + + L + V             FAGE+  V    T  GA +SG   A+  L
Sbjct:   37 LEALDRAGGRVHTARPFRLGHAAELGAAWIHGENGNPLYRLAHMHGLLATGRASGQDGDVDHFFTERGERLPSGTVSQVCKRFSEIMGDAFGETDRVYGGTGGTEARSAAAGHRSVGDFLDEK--FFSPSGSWDEASKGVFEWCKRIECTDEACSSMYEFN-LSELGH---YSGFEGRF-FNSLGPRGFSAIVDTLVDRLPAGSVIFNKAVSSIHWGLRTEQTAAEGVAGAHPVRVVCEDGSEFHADHVIVTVSLGYLKANGASMFHPPLPPRKLRAIERLGFGAVSKIFLEFESPFWPDGWDSMQFVWNEGPEDRAITAGSWKDSWYKKITGFNSVARHPNVL-CGWVTGRE--ARHMDTLKSSVVGDMCVRLLRQFTRLPVSRLVQVLVTTWNKDRFFQGAYTYIPLGVNARTEQQALAEPVPGRRDPQTSLQVLFAGEATDVNFYTTTHGALLSGQREARRLL 492          

Query:  226 HNFA----IFESSYKIGGRI-QTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLE-LGQPIENDILFVWDTDSCQDITELFNERVNKLKNIL---EYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNEL-----IFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            HNF     + E+  +IGGR+      GG     G   V+G   NPI  +   + + +  LG+  E        TD   D    F+   N L +I+       E  +D  +  EK  +       +   S  +LE  +L      +E   GA L ++SA +   H+E +    G          G   +++ L +     ++L   VK +D+S   E VK+ T     +    V++T+P  L+    ++F P LP  K+ A + +      ++  +FP RFW  K        ++ P ++      +F+      ++  + +  ++    SG      R D+   ++     ++++ +FP          F+T W S+ ++  ++S V PG +    + L + + G L FAGE+       T+ GAY+SG+  A
Sbjct:  408 HNFGLKVIVLEARERIGGRVWDDRSLGGTTVGRGAQIVNGCVNNPISLMCEQLGIRMHVLGEACELLDESGRVTDPALDKRMDFH--FNALLDIIAQWRTTTEPAHDVSLGAEKMEELTHAFRKESGLSFGELEEKLLQFHLANLEYACGANLRQVSARS-WDHNEFFAQFAGDHTLLTA---GYSTILHRLAEGL--DVRLHTPVKRVDYS--GECVKVHTATGMTYIADKVLVTIPLALMQLGVLEFCPPLPERKIKALQSLGAGLIEKIGLQFPFRFWEHKIRGADYFGHLPPSHDRRGLFGVFY------DMDPKGEQCVLMSVVSGDSVALIR-DLSDSQVVSQSMQALRAIFPEQNVPDPLRWFVTRWGSDPWALMAYSYVRPGGTGEAYDVLAQDLNGKLFFAGEATNRHFPQTVTGAYLSGVREA 823          

Query:  226 HNFA----IFESSYKIGGRI-QTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLE-LGQPIENDILFVWDTDSCQDITELFNERVNKLKNIL---EYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNEL-----IFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            HNF     + E+  +IGGR+      GG     G   V+G   NPI  +   + + +  LG+  E        TD   D    F+   N L +I+       E  +D  +  EK  +       +   S  +LE  +L      +E   GA L ++SA +   H+E +    G          G   +++ L +     ++L   VK +D+S   E VK+ T     +    V++T+P  L+    ++F P LP  K+ A + +      ++  +FP RFW  K        ++ P ++      +F+      ++  + +  ++    SG      R D+   ++     ++++ +FP          F+T W S+ ++  ++S V PG +    + L + + G L FAGE+       T+ GAY+SG+  A
Sbjct:  400 HNFGLKVIVLEARERIGGRVWDDRSLGGTTVGRGAQIVNGCVNNPISLMCEQLGIRMHVLGEACELLDESGRVTDPALDKRMDFH--FNALLDIIAQWRTTTEPAHDVSLGAEKMEELTHAFRKESGLSFGELEEKLLQFHLANLEYACGANLRQVSARS-WDHNEFFAQFAGDHTLLTA---GYSTILHRLAEGL--DVRLHTPVKRVDYS--GECVKVHTATGMTYIADKVLVTIPLALMQLGVLEFCPPLPERKIKALQSLGAGLIEKIGLQFPFRFWEHKIRGADYFGHLPPSHDRRGLFGVFY------DMDPKGEQCVLMSVVSGDSVALIR-DLSDSQVVSQSMQALRAIFPEQNVPDPLRWFVTRWGSDPWALMAYSYVRPGGTGEAYDVLAQDLNGKLFFAGEATNRHFPQTVTGAYLSGVREA 815          

Query:  226 HNFA----IFESSYKIGGRI-QTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLE-LGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKN--FKDLLMESSDYFE-----SMTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNEL--IFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            HNF     + E+  +IGGR+      GG     G   V+G   NPI  +   + + +  LG+  E        TD   D    F+   N L +I+       +    +P  +    + + E +  F      S  +LE  +L      +E   GA L ++SA +   H+E +    G          G   +++ L +     ++L   VK +D+S   E VK+ T     +    V++T+P  L+    ++F P LP  K+ A + +      ++  +FP RFW  K        ++ P ++   +F          +  +  ++    SG      R D+   ++     ++++ +FP          F+T W S+ ++  ++S V PG +    + L + + G L FAGE+       T+ GAY+SG+  A
Sbjct:  303 HNFGLKVIVLEARERIGGRVWDDRSLGGTTVGRGAQIVNGCVNNPISLMCEQLGIRMHVLGEACELLDESGRVTDPALDKRMDFH--FNALLDII-----AQWRTTTEPAHDVSLGEKMEELTHAFRKESGLSFGELEEKLLQFHLANLEYACGANLRQVSARS-WDHNEFFAQFAGDHTLLTA---GYSTILHRLAEGL--DVRLHTPVKRVDYS--GECVKVHTATGMTYIADKVLVTIPLALMQLGVLEFCPPLPERKIKALQSLGAGLIEKIGLQFPFRFWEHKIRGADYFGHLPPSHDRRGLFGVFYDMDPKSSTGEQCVLMSVVSGDSVALIR-DLSDSQVVSQSMQALRAIFPEQNVPDPLRWFVTRWGSDPWALMAYSYVRPGGTGEAYDVLAQDLNGKLFFAGEATNRHFPQTVTGAYLSGVREA 720          

Query:  439 QDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLME-----SSDYFESMTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKE--SEVVKIVTDNDEE---FHCKNVIITLPSELLARE--SIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLI-QVIKNVDPVNEL-IFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSVGP-------------LHFAGESVIVELIGTMQGAYISGIEAA 1467
            +D+T  F  + +KL+++     E  YD++ + +   ++ L E      SD + S  D  R +L   +  +E     PL  LS L     D+ ++F    L  R      G   +     +  D IKL   V+ + ++     EV+   T +  +   + C  V+ TLP  +L ++  +++F P LP  K +A + +   N  ++   F   FW     L   V        EL +FW       L A     L+    +G  +     +V  + +       +K +F  +         +T W ++ ++ GS+S V+ G +  D + + + + P             L FAGE  I     T+ GA +SG+  A
Sbjct:  363 RDVTAEFLVK-SKLRDLNAACRE--YDELAESQIKLEEKLQELEANPPSDVYLSSRD--RQILDWHFANLEFANATPLSTLS-LKHWDQDDDFEFSGSHLTVR-----NGYSCVPVALAEGLD-IKLNTAVRQVKYTPAVGCEVLTQHTRSSSQSLIYKCDAVLCTLPLGVLKQQPPAVQFFPPLPEWKTTAIQRMGFGNLNKVVLCFDRVFWDLNVNLFGHVGSTTASRGELFLFWNLYKAPILLA-----LVAGEAAGIME-----NVSDDVIVARAMAVLKGIFGSSAVPQPKETVVTRWRADPWARGSYSYVAAGSNGNDYDLMAQPIAPPPSLPGSPQPIHRLFFAGEHTIRNYPATVHGALLSGLREA 714          

Query:  202 RYLHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHG-KKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLERTVLYTCMEI-YRGAPLHELSAL-AEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFT-SGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAAKHSL 1479
            ++L   G H+F I E   ++GGR +  + GG +   G  WVH     NPI+ ++       E G+ + N         S +  +EL ++R  + K                P+ + +  L +    ++    ++  V Y  ++  Y   P  EL +  AE++  +          F ++D  G   +   + K+F D+I L   V+ I +S     V + T +   +  +  + T  + +LA + + F P LP  K+ +   VP   Y ++F +FPT FW + E+++   KN         W +     L        I H T +G +        ++E   EI+ E +++++      P D  F + W    F+ GSF  V  G +K D   L  +V  L+FAG++   E  G +Q AY+SG   A   L
Sbjct:   45 KHLTDAGFHDFLILEGEGRVGGRFKQAEVGGAMIEEGANWVHHVTDDNPIWKLVQKN----EKGKDVTNKTAINHFYSSLEKASELAHQRRQQQK----------------PDMSLRVGLAQVG--WKPKNPVDDVVEYHGVDFEYPDKP--ELDSFSAEVRGRD----------FFVLDSRGYGHIWQEMAKEFMDKIILNAVVREIRYSNYG--VTVTTTDGRTYSGRYSLCTFSTGVLATDMVNFSPPLPEWKMESIYKVPMRYYTKIFLQFPTDFWDDNEFILYAHKN---RGHYPIWMDIDRPGLAPGSK---ILHVTVTGDEALRVEGQSDEETKAEIMRE-LRKVYGSDIPEPID-FFYSRWSRNNFTRGSFPNVMIGTTKEDFHNLQGNVKSLYFAGDATEYEWWGFVQSAYLSGRRKATEIL 431          

Query:  715 NFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQ--VIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSR--FDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFSGSFSKVSPGISKVDIEELCKSVGPLHFAGES 1407
            +F   D  G   + N   + FKD+IKL   V  + ++     V++ T + + +    V+ T  + +LA + ++F+P LP  K  A+   P   Y ++F KF  +FW + E+++   + +   PV     +Q+ +   +     +IL+   T    +   R  F   K E+ E+    +K+++ +    P+D+ +     +    G++S+V  G      EEL K++G LHFAGE+
Sbjct:   36 DFYSTDQRGFYNIFNETVETFKDKIKLNETVARVKYNNTG--VEVTTSSGDVYSADYVVCTFSTGVLASDMVEFVPPLPKWKQEAYLSHPMSIYTKIFLKFDHKFWDDNEYILHASMKRGYYPV-----FQDLARPGIFPVNSSILLVTVTDTESRRIERQPFAETKREIVEM----LKKIYGNNVTEPTDIFYDRWSQNPYIRGAYSEVVVGTGSKSFEELAKNLGNLHFAGEA 259          

Query:  208 LHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKY--YDKVIDPEKNFKDLLMES-----------SDYFES---MTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQ-IKLKHKVKVIDWSKE-----SEVVKIVTDNDEEFHCKNVIITLPSELL-ARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFT-SGSQ------QGSSRFDVEKEELTEIVTESMK--RMFPHTYCAPS-DVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSVGPLH------------FAGESVIVELIGTMQGAYISGIEAAKHSL 1479
            L    + +  I E+S +IGGRI T     ++   G GW+H    NP+YD    I+V L  G        F  D      +T     + N+L   L   NE Y  Y+K+ D  K     L ES             Y E+    + L+R++    M     +   +     +I+    Y  +E         P G  KL+  + +D  ++ ++  H+V  I W  +     S VV I   N E F  ++VI+TLP  +L +R  + F P LP  K  A   +      R++  F   FW  +      IK +      + W N    N  +    + I + T  GS        G +   +E     EI  E  +  + F      P    +  T W S + S GS++ +       DI+ L   +  L             FAGE+       T  GAYISG+  AK  L
Sbjct:   23 LQNSKEVDVTILEASSRIGGRIHTSTINNEVVELGAGWIHDSTSNPLYDAAREINVVLSKG--------FNCDASEFGSVTFYTLGQANELPTKL--ANEVYEAYEKIYDDCKTTASELNESLGLGIYYGNKFEHYLENNAEHSSLKRSLFEWIMRNECHSSGVKSLENVDIKSSPEYSVDE---KDSFTLPHGYNKLLERIFEDLDEETVRFNHEVVSIKWKPKPEETSSSVVSITCSNGEIFTAEHVIVTLPLGVLKSRHEVIFNPPLPQIKKDAINRLGYGTINRIYLVFEKAFWSNE------IKGMG-----LLWTNLDSNNWPSWVKELYIFYPTHKGSNVLVTWLSGEAAIQIESISDQEIAHECTRVLKAFTGLKEIPGIKEVMKTKWHSNKLSRGSYTYIPRYSGGADIDILASPLPHLEGEAQGNVPCKILFAGEATNRSAYATTHGAYISGVREAKRIL 468          

Query:  784 QIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDV-LFITHWDSERFS-GSFSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAAKHSL 1479
            +I+L+ +V+ I +S     V +   N   +  ++ I T  S +L    + F+P+LP  K  A   VP   Y ++F KF  +FW +KE+++   K      +   +QN     +  +E  +L+   T     GS    +E +   +  +E M  +       P    +F   W  + ++ G++S  +      D + +   +  L FAGE+   E  G MQGAY++G  AAK  L
Sbjct:    1 RIELEKEVESISYSNAGVTVNLTNGN--VYTAEHAICTFSSGVLNNGLVNFIPRLPKWKQDALSKVPMSFYTKIFLKFQIKFWEDKEFILHASKR---RGDFPVFQNVP---INTKEGGVLMATIT-----GSEALRIENQSDEDTRSEVMATLRQLYGVIPEPTEMFYARWSKDPYTRGAYSDPTLDARPCDFDNMLLPLDTLFFAGEATSEEWTGYMQGAYLTGKHAAKRVL 221          

Query:  238 IFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKY--YDKVIDPEKNFKDLLMES 567
            I E+S +IGGRI T     ++   G GW+H    NP+YD    I+V L  G        F  D      +T     + N+L   L   NE Y  Y+K+ D  K     L ES
Sbjct:   33 ILEASSRIGGRIHTSTINNEVVELGAGWIHDSTSNPLYDAAREINVVLSKG--------FNCDASEFGSVTFYTLGQANELPTKL--ANEVYEEYEKIYDDCKTTASELNES 134          

Query:  238 IFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPL-ELGQPIENDILFVWDTDSCQDITELFNERVN-KLKNILEYVNEKYYDK-----------VIDPEKNFKDLLMESSDYFESMTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPL---GGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNE-----LIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFSG-SFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            + E+  +IGGR+      G +   G   V+G   NPI  +   +D+ + +LG+  E   LF       Q      ++R++     IL+ V+E   DK           V + +KNF   L ES   F   ++LE  VL    + +E   G+ L ++SA +       +D  E    F     L   G   L++ L +     I     V+ ID+S   E VK+++ N  ++  + V++T+P  LL +  I F P LP  KL A   +      ++  +FP RFW +K        N+ PV E      +F+      +L  +  N ++    SG    + R D+E++++     + ++ +F           F+THW  + +S  S+S V  G S    + L + V G + FAGE+       T+ GAY+SG+  A
Sbjct:  418 VLEARDRIGGRVWDDTSLGVMVGRGAQIVNGCVNNPIALMCEQMDIKMHKLGERCE---LF---QKGGQATDPTIDKRMDFHFNAILDVVSEWRKDKSQSQDTPLGEKVQEVKKNF---LQESGMQF---SELEEKVLQFHLSNLEFACGSTLDKVSARS-------WDHNEFFAQFSGDHTLLTKGYYVLLHKLAEAL--DICTNCPVQAIDYS--GETVKVISSNGSQWTAQKVLVTVPLILLQKNLIHFNPPLPERKLKAIHSLGAGIIEKIALQFPCRFWDKKIQGADYFGNIPPVPEKRGMFSVFY------DLDPQGKNAVLMSVISGDAVAAVR-DMEEKDVVNECMKVLRELFKEQEVPEPVNYFVTHWSKDVWSQMSYSFVKTGGSGEAYDILAEDVQGKVFFAGEATNRHFPQTVTGAYLSGVREA 823          

Query:  805 VKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNE-----LIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFSG-SFSKVSPGISKVDIEELCKSV-GPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            V+ ID+S   E VK+++ N  ++  + V++T+P  LL +  I F P LP  KL A   +      ++  +FP RFW +K        N+ PV E      +F+      +L  +  N ++    SG    + R D+E++++     + ++ +F           F+THW  + +S  S+S V  G S    + L + V G + FAGE+       T+ GAY+SG+  A
Sbjct:  353 VQAIDYS--GETVKVISSNGSQWTAQKVLVTVPLILLQKNLIHFNPPLPERKLKAIHSLGAGIIEKIALQFPCRFWDKKIQGADYFGNIPPVPEKRGMFSVFY------DLDPQGKNAVLMSVISGDAVAAVR-DMEEKDVVNECMKVLRELFKEQEVPEPVNYFVTHWSKDVWSQMSYSFVKTGGSGEAYDILAEDVQGKVFFAGEATNRHFPQTVTGAYLSGVREA 571          

Query:  787 IKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITH----WDSERFSGS--FSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            ++L   V  I W +++E  K++T +D  F CK VIIT P  L A+  I + P LP  +    + +P  +  +    + T FW  K +  +++       +  F   C   +  +   N  +  F +G QQ S     E E+    V  S+ R     Y  P    FI +    W  E +SG    + ++PG+       L    G + +AG     +  G M GA  +G  AA
Sbjct:  239 VRLGSAVTAI-W-QDAEWAKVMTSSDT-FLCKAVIITCPPHLAAK--ISYQPALPSMREFLTQNMPVGHMMKFIITYQTAFWKVKGFSGEIVAGSS--TDCPF---CVTFDATSPRGNAALVGFLAG-QQASHWGTKEAEQRKTAVISSLVR-----YLGPEAASFIHYEEKDWAKEEYSGGCPVNVMAPGLLTYYHPSLRTPCGRIFWAGTETATQWCGYMSGAVQAGQRAA 455          

Query:  226 HNFAIFESSYKIGGRIQTVKFGGKIFSSGPGW---VHGKKGNPIYDILVNI----DVPLELGQPIENDILFVWDTDSCQ-------------DITELFNERVNKLKNILEYVNEKYYDKVIDPEKN------FKDLLMES-SDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKD-FKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELL-------ARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSC-QNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSVGPLHFAGE 1404
            H   I E+S ++GGR++T +      +   GW   +   +    ++I++NI    +V L     ++N+  ++ +                  ++TE  NER      +L+   +K  +  +   +N      FK+    S  +Y +   +L +  +    ++     L   +AL E+ +D+  D    I  + +    GG  L +   +D  K  + L  KV  I  S     VK  T N+          TLP++L+       A   I F P L I+K+ A + V   +  ++F  F  +FW E E +       D  +  I++ + S  QN   +   +L+  +T  S           E+L E+V   + ++      +    + +  W S+ ++ G+F+ ++P       +EL +S G +HFAGE
Sbjct:   75 HQVTILEASGRVGGRLETYR------NKEEGWYAELGAMRIPSFHEIVLNITEILNVSLNPFTMVDNNTYYLTNGVKATTKEGTTNPEVLMYNVTE--NERHKSADELLQMALKKVGNGHLYVAQNHGCQYLFKNYDHYSVKEYLKEEGELSQQAIRMIGDLLNEQSL-LFTALTEMLYDQS-DVNNSITYYEVT---GGFDLFSEALRDSLKSTLHLNSKVVRISQSDRGVTVKYQTPNESSLK------TLPADLVLVTTTTKAALFIDFDPPLSIQKMEAMRSVHYDSATKIFLTFREKFW-ESEGIHGGKSITDRPSRFIYYPSHSFPQN---QTIGVLLASYT-WSDDSLLFLGASDEDLKELVLRDLAQIHGERVRSLCTGVIVKRWSSDPYTLGAFALLTPYQHIEYSKELFRSEGRIHFAGE 480          

Query:  508 KYYDKVIDPEKNFKDLLME-----SSDYFESMTDLERTVL---YTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKES-EVVKIVTDNDEE---FHCKNVIITLPSELLARE--SIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFW-PEKEWLIQVIKNVDPVNEL-IFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFS-GSFSKVSPGISKVDIEELCKSVGP-------------LHFAGESVIVELIGTMQGAYISGIEAA 1467
            K YD++ + +   ++ L E      SD + S  D  R +L   +  +E     PL  LS L     D+ ++F    L  R      G   +     +  D IKL   V+ + ++    EV+ + T +  +   + C  V+ TLP  +L ++  +++F+P LP  K SA + +   N  ++   F   FW P       V        EL +FW       L A     L+    +G  +     ++  + +       +K +F  +         +T W ++ ++ GS+S V+ G S  D + + + + P             L FAGE  I     T+ GA +SG+  A
Sbjct:  465 KEYDELAEMQVKLEEKLQELEANPPSDVYLSSRD--RQILDWHFANLEFANATPLSTLS-LKHWDQDDDFEFTGSHLTVR-----NGYSCVPVALAEGLD-IKLNTAVRQVRYTASGCEVIAVNTRSTTQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAIQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLA-----LMAGEAAGIME-----NISDDVIVGRCLAILKGIFGSSAVPQPKETVVTRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPAIPGASQPVPRLFFAGEHTIRNYPATVHGALLSGLREA 795          

Query:  151 MYDTXXXXXXXXXXXXXRYLHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFSGSFSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAAKHSL 1479
            MYDTIIIGAGIAGLSAGRYLHKKGQHNFAIFES+YKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVK IDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNC+CQNLCAE+DNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFSGSFSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAAKHSL
Sbjct:    1 MYDTIIIGAGIAGLSAGRYLHKKGQHNFAIFESAYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIENDILFVWDTDSCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFESMTDLERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYLCKDFKDQIKLKHKVKAIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCACQNLCAEDDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFSGSFSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAAKHSL 443          

Query:  208 LHKKGQHNFAIFESSYKIGGRIQTVKFGGKIFSSGPGWVHGKKGNPIYDILVNIDVPLELGQPIEN---DILFVWDTD--SCQDITELFNERVNKLKNILEYVNEKYYDKVIDPEKNFKDLLMESSDYFE------SMTD-LERTVLYTCMEIYRGAPLHELSALAEIQHDEVYDFEEGILNFRIVDPLGGLKLINYL--CKDFKDQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEK-EWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVLFITHWDSERFSGSFSKVSPGISKVDIEEL--CKSVGPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            L K G  +F I E+   IGGR++ + F G  +S GP W+HG+  NPI+ +        ELG  + N   D  +  D    S  +  +LF  + NKL+  ++           D   NF    +E+    E      + TD L + + Y       G    + SAL      ++Y+      +F  V+    +K+INY        D+  ++   KV     E + +KIVT + +E+  +  I T+P  ++ +  IK  P    E       +    Y R+F + P   W    +WL+ +  + +  NE+  W+N +      +    LI H  + S+  S         L   +  S+K +  + Y   +D       +     GSF   S   +  D+E L    +   L FAG+S  +E  GT+QGA+ +GI AA
Sbjct:   21 LKKLGISDFLILEARGNIGGRVRQITFCGSEYSIGPEWLHGQTSNPIFHL-----AKAELGLKVRNSEYDKFYFTDPSNLSVTNRQKLFKSKFNKLRKAVD-----------DKLANFSFESLENKSISEVLKIDANQTDTLSQFINYWAFNFENGLESDKFSALLYKMSSDIYNNVHSFSDFHFVENDSFIKIINYFRASAGLNDK-NIRFNEKVEKLFCEEDKIKIVTTSGKEYLAEYCICTIPISVIGKHLIKIQPDFSNEIYETISKLKFSTYSRVFVELPKPNWINNYDWLVHLSDDFE--NEICLWKNPN------DHPKTLIGHIYNLSKSIS-------HNLERKIEISLKHILGNEYRGINDFQVFCLENCPYSFGSFPTASSEFNMKDVENLKSFNNSSRLLFAGDSYTLEYFGTVQGAFNTGIHAA 425          

Query:  640 APLHELSALAEIQHDEVYDFEEGILNFRIVDPLGG------LKLINYLCKDFKDQ---IKLKHKVKVIDWSKESEVVKIVTDNDE----EFHCKNVIITLPSELLARES----IKFLPKLPIEKLSAWK--YVPGV-----NYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDV-LFITHWDSERFS-GSFSKVSPGISKVDIEELCKSV----GP-LHFAGESVIVELIGT--MQGAYISGIEAA 1467
            +PLH+LS   +I HD      +    F+ V PL        + +IN   K   +    +  K   K ID+    E++    D +      + CK+ I+T+P  +LAR S    I F+P LP +K+ + K   +P +     N   L  +    FW +K +    + + + V   +F+    C      +  +L+CH   G++  +   D   EE+ +I+   ++ M+      P  +   +T W  + FS GS++   P  +  D +   +++     P + FAGE  + E        GA ++G+  A
Sbjct:  205 SPLHQLSL--DILHDIAIAANKKTRVFK-VKPLSESEISTWIAMINLRIKAMSEHPPSVTTKVITKKIDYRNPDEIIVTCIDPNTGDLIRYKCKHCIVTVPVGVLARLSNIAAINFVPTLPEDKIKSIKRLALPSIGAETHNKVVLRYRPSDVFWDKKRFFSNHLCDTE-VKAFVFF----CH--FPGKPGLLVCHIWGGTEIKT--IDHTDEEIVDIILTLLQGMYQKLGTLPKPIQTLVTRWSEDPFSLGSYTPGGPLSTNDDRKSYARAIPEDGSPRIFFAGEGTLGEFEAKECTHGALMNGMHKA 501          

Query:  640 APLHELSALAEIQHDEVYDFEEGILNFRIVDPLGG------LKLINYLCKDFKDQ---IKLKHKVKVIDWSKESEVVKIVTDNDE----EFHCKNVIITLPSELLARES----IKFLPKLPIEKLSAWK--YVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLCAEEDNILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDV-LFITHWDSERFS-GSFSKVSPGISKVDIEELCKSV----GP-LHFAGESVIVELIGT--MQGAYISGIEAA 1467
            +PLH+LS   +I HD      +    F+ V PL        + +IN   K   +    +  K   K ID+    E++    D +      + CK+ I+T+P  +LAR S    I F+P LP +K+ + K   +P +       K   R+ P   +    + + + V   +F+    C      +  +L+CH   G++  +   D   EE+ +I+   ++ M+      P  +   +T W  + FS GS++   P  +  D +   +++     P + FAGE  + E        GA ++G+  A
Sbjct:  205 SPLHQLSL--DILHDIAIAANKKTRVFK-VKPLSESEISTWIAMINLRIKAMSEHPPSVTTKVITKKIDYRNPDEIIVTCIDPNTGDLIRYKCKHCIVTVPVGVLARLSNIAAINFVPTLPEDKIKSIKRLALPSIG-AETHNKVVLRYRPSDRFFSNHLCDTE-VKAFVFF----CH--FPGKPGLLVCHIWGGTEIKT--IDHTDEEIVDIILTLLQGMYQKLGTLPKPIQTLVTRWSEDPFSLGSYTPGGPLSTNDDRKSYARAIPEDGSPRIFFAGEGTLGEFEAKECTHGALMNGMHKA 495          

Query:  781 DQIKLKHKVKVIDWSKESEVVKIVTDNDEEFHCKNVIITLPSELLARESIKFLPKLPIEKLSAWKYVPGVNYCRLFAKFPTRFWPEKEWLIQVIKNVDPVNELIFWQNCSCQNLC----AEEDN---ILICHFTSGSQQGSSRFDVEKEELTEIVTESMKRMFPHTYCAPSDVL-FITH----WDSERFSGS--FSKVSPGISKVDIEELCKSVGPLHFAGESVIVELIGTMQGAYISGIEAA 1467
            D I ++  V  I+  ++  +++ V+    ++  ++VII +P  L+   +I+F P L   K+  +  V   +  ++   + TRFW  + +  ++I N  P     F   CS   LC    A  +N    L+C    G +Q        K E  E V +S+++ F      P  V  FI +    W  E F G    + V PG+ +     L      L+FAG  +     G M+GA  SG  AA
Sbjct:  250 DTIDIQTVVTSIEKKEDYSLIQTVSGT--QYKARHVIIAVPPHLIL--NIQFDPPLNPTKIEYFSSVIPGHSIKIILTYETRFWLSEGFSGEIITNGGPS----FCDGCSSGPLCVVFDATTENHSPALVCFI--GGEQALQYESKTKTERKEAVLKSLEQFF-----NPLKVRDFIAYCEKIWRHESFVGGCPVTIVPPGVGRYITHALTDPENELYFAGSELGKMWGGFMEGAVESGERAA 477