Tubulin-specific chaperone D

Overview


Name	Tubulin-specific chaperone D
Smed ID	SMED30002829
Length (bp)	3748

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Tubulin-specific chaperone D (SMED30002829) t-SNE clustered cells

Violin plots show distribution of expression levels for Tubulin-specific chaperone D (SMED30002829) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Tubulin-specific chaperone D (SMED30002829) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Tubulin-specific chaperone D (SMED30002829) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30002829

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X2 cell	SMED30002829	SMESG000000964.1	SmedASXL_014074	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
nervous system	SMED30002829	SMESG000000964.1	dd_Smed_v4_10610_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30002829	SMESG000000964.1	dd_Smed_v4_10610_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30002829	SMESG000000964.1	dd_Smed_v4_10610_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30002829	SMESG000000964.1	dd_Smed_v4_10610_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Human
Match: TBCD (tubulin folding cofactor D [Source:HGNC Symbol;Acc:HGNC:11581])

HSP 1 Score: 816.994 bits (2109), Expect = 0.000e+0
Identity = 470/1208 (38.91%), Postives = 698/1208 (57.78%), Query Frame = 2

Query:   50 KEDDEDLKY-IILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS-------ANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKW--EREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELI-----LAMESPNDIPETLKTE----IKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLW-------YKFLSECTTHKEKFVRTAAIEAFPEFMDCYCF----DRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGI----TNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYM-KDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETL-ISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            + +DE L +   L  F    E   L+  L+E+ G   + E+  +R + I ++YQ QPHLLDP+LE +++  + ++             F+ +Y++ K RGYKT +RL PHEV+D+EPVL +++     D+E W+ RY+LLLWLS+  +IPFD +  D          +  I  RIL+  + +L+  D ++ AAA ++S+F+ RPD +K   + E + W++  +     + + G   M G L+    +FK GKRED LP++  +L     +D  +     + LL +L  KLVQR+GL FLK KV  WRYQRG R L  NL   +     + P                 +++ED +V E +  V++ L+  LK+  T VRWSAAKG+GR+  RLP++LADD+V ++L  FS  E   +WHG CLALAELGRRG LLP RL +V+ +I+KAL YDEK G CS G NVRDAACYVCWAFARAY P+ELKP+V  I+S L++  +FDR +N RRAA+AAFQENVGRQG FPHGI+ILTT DYFAV N +NCFL +S+FIA F EY +PMIDHLV +K+ HWD  IREL A+AL+ L   APE+   +V P L++     DL+ R GSI+A  E+      LA +    + + L  +    +K I   L  R  +RGL G+LMR+A+C LI   S +KM F+GD +ID W        + L   ++H  + ++ AA+ A       Y      + D  I+ E    Y+ +     + T   +  A     LG  P ++L+        L  +   +  +  TS  E V    + E+R   L ++  IC+TVG+     +E +    + +IY  LL  +DDYT DS GD+G  VR++AM SL   + LL+ S   + E+ +    + I+  ++QQA EKIDR R  A  +F  L++     IP +P    ++ +F +     + W+AP   FP  ++LL    YRY ++LGLVVS+GG+TE T++HS ++L   +K  + D +     S  +L++F++    +RV  PL K +D +     +  F   +     + ++   K EI  +KDIQK+ SGI VFC M+QF   + R+A+  L +L+ H+FP+IRK TA+ +Y++LL Y ++V  D   E++ +L +T WD ELA VRE RN++C+L  +P P+L+ +
Sbjct:   15 EAEDETLAFGAALEAFGESAETRALLGRLREVHGGGAEREVALERFRVIMDKYQEQPHLLDPHLEWMMNLLLDIVQDQTSPASLVHLAFKFLYIITKVRGYKTFLRLFPHEVADVEPVLDLVTIQNPKDHEAWETRYMLLLWLSVTCLIPFDFSRLDGNLLTQPGQARMSIMDRILQIAESYLIVSDKARDAAAVLVSRFITRPD-VKQSKMAEFLDWSLCNLARSSFQTMQGVITMDGTLQALAQIFKHGKREDCLPYAATVLRC---LDGCRLPESNQTLLRKLGVKLVQRLGLTFLKPKVAAWRYQRGCRSLAANLQLLTQGQSEQKPLILT------------EDDDEDDDVPEGVERVIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRALADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEPQELKPFVTAISSALVIAAVFDRDINCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQVFPRLLSMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQLYDRQLYRGLGGQLMRQAVCVLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLA-----LGALPGFLLKGR------LQQVLTGLRAVTHTSP-EDV---SFAESRRDGLKAIARICQTVGVKAGAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMTSLMDLTLLLARS---QPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCEMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYSDVVGADVLDEVVTVLSDTAWDAELAVVREQRNRLCDLLGVPRPQLVPQ 1188

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Human
Match: TBCD (tubulin folding cofactor D [Source:HGNC Symbol;Acc:HGNC:11581])

HSP 1 Score: 798.119 bits (2060), Expect = 0.000e+0
Identity = 470/1246 (37.72%), Postives = 698/1246 (56.02%), Query Frame = 2

Query:   50 KEDDEDLKY-IILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS-------ANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKW--EREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELI-----LAMESPNDIPETLKTE----IKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLW-------YKFLSECTTHKEKFVRTAAIEAFPEFMDCYCF----DRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGI----TNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYM-KDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETL-ISIIDKTKLEICTTKDIQKIKSGIEV--------------------------------------FCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            + +DE L +   L  F    E   L+  L+E+ G   + E+  +R + I ++YQ QPHLLDP+LE +++  + ++             F+ +Y++ K RGYKT +RL PHEV+D+EPVL +++     D+E W+ RY+LLLWLS+  +IPFD +  D          +  I  RIL+  + +L+  D ++ AAA ++S+F+ RPD +K   + E + W++  +     + + G   M G L+    +FK GKRED LP++  +L     +D  +     + LL +L  KLVQR+GL FLK KV  WRYQRG R L  NL   +     + P                 +++ED +V E +  V++ L+  LK+  T VRWSAAKG+GR+  RLP++LADD+V ++L  FS  E   +WHG CLALAELGRRG LLP RL +V+ +I+KAL YDEK G CS G NVRDAACYVCWAFARAY P+ELKP+V  I+S L++  +FDR +N RRAA+AAFQENVGRQG FPHGI+ILTT DYFAV N +NCFL +S+FIA F EY +PMIDHLV +K+ HWD  IREL A+AL+ L   APE+   +V P L++     DL+ R GSI+A  E+      LA +    + + L  +    +K I   L  R  +RGL G+LMR+A+C LI   S +KM F+GD +ID W        + L   ++H  + ++ AA+ A       Y      + D  I+ E    Y+ +     + T   +  A     LG  P ++L+        L  +   +  +  TS  E V    + E+R   L ++  IC+TVG+     +E +    + +IY  LL  +DDYT DS GD+G  VR++AM SL   + LL+ S   + E+ +    + I+  ++QQA EKIDR R  A  +F  L++     IP +P    ++ +F +     + W+AP   FP  ++LL    YRY ++LGLVVS+GG+TE T++HS ++L   +K  + D +     S  +L++F++    +RV  PL K +D +     +  F   +     + ++   K EI  +KDIQK+ SGI V                                      FC M+QF   + R+A+  L +L+ H+FP+IRK TA+ +Y++LL Y ++V  D   E++ +L +T WD ELA VRE RN++C+L  +P P+L+ +
Sbjct:   15 EAEDETLAFGAALEAFGESAETRALLGRLREVHGGGAEREVALERFRVIMDKYQEQPHLLDPHLEWMMNLLLDIVQDQTSPASLVHLAFKFLYIITKVRGYKTFLRLFPHEVADVEPVLDLVTIQNPKDHEAWETRYMLLLWLSVTCLIPFDFSRLDGNLLTQPGQARMSIMDRILQIAESYLIVSDKARDAAAVLVSRFITRPD-VKQSKMAEFLDWSLCNLARSSFQTMQGVITMDGTLQALAQIFKHGKREDCLPYAATVLRC---LDGCRLPESNQTLLRKLGVKLVQRLGLTFLKPKVAAWRYQRGCRSLAANLQLLTQGQSEQKPLILT------------EDDDEDDDVPEGVERVIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRALADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEPQELKPFVTAISSALVIAAVFDRDINCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQVFPRLLSMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQLYDRQLYRGLGGQLMRQAVCVLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLA-----LGALPGFLLKGR------LQQVLTGLRAVTHTSP-EDV---SFAESRRDGLKAIARICQTVGVKAGAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMTSLMDLTLLLARS---QPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVDFPSATLVCVGTVQMYAHTHLRLGAPGPHCAHGSALPRFCEMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYSDVVGADVLDEVVTVLSDTAWDAELAVVREQRNRLCDLLGVPRPQLVPQ 1226

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Human
Match: TBCD (tubulin folding cofactor D [Source:HGNC Symbol;Acc:HGNC:11581])

HSP 1 Score: 258.07 bits (658), Expect = 8.958e-75
Identity = 141/394 (35.79%), Postives = 227/394 (57.61%), Query Frame = 2

Query: 2402 LRTSKIESVRTSKWGEARSYALTSLIDICETVGI----TNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYM-KDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETL-ISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            LR     S     + E+R   L ++  IC+TVG+     +E +    + +IY  LL  +DDYT DS GD+G  VR++AM SL   + LL+ S   + E+ +    + I+  ++QQA EKIDR R  A  +F  L++     IP +P    ++ +F +     + W+AP   FP  ++LL    YRY ++LGLVVS+GG+TE T++HS ++L   +K  + D +     S  +L++F++    +RV  PL K +D +     +  F   +     + ++   K EI  +KDIQK+ SGI VFC M+QF   + R+A+  L +L+ H+FP+IRK TA+ +Y++LL Y ++V  D   E++ +L +T WD ELA VRE RN++C+L  +P P+L+ +
Sbjct:   72 LRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKAGAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMTSLMDLTLLLARS---QPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCGMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYSDVVGADVLDEVVTVLSDTAWDAELAVVREQRNRLCDLLGVPRPQLVPQ 462

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Human
Match: TBCD (tubulin folding cofactor D [Source:HGNC Symbol;Acc:HGNC:11581])

HSP 1 Score: 239.965 bits (611), Expect = 5.106e-68
Identity = 141/432 (32.64%), Postives = 227/432 (52.55%), Query Frame = 2

Query: 2402 LRTSKIESVRTSKWGEARSYALTSLIDICETVGI----TNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYM-KDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETL-ISIIDKTKLEICTTKDIQKIKSGIEV--------------------------------------FCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            LR     S     + E+R   L ++  IC+TVG+     +E +    + +IY  LL  +DDYT DS GD+G  VR++AM SL   + LL+ S   + E+ +    + I+  ++QQA EKIDR R  A  +F  L++     IP +P    ++ +F +     + W+AP   FP  ++LL    YRY ++LGLVVS+GG+TE T++HS ++L   +K  + D +     S  +L++F++    +RV  PL K +D +     +  F   +     + ++   K EI  +KDIQK+ SGI V                                      FC M+QF   + R+A+  L +L+ H+FP+IRK TA+ +Y++LL Y ++V  D   E++ +L +T WD ELA VRE RN++C+L  +P P+L+ +
Sbjct:   72 LRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKAGAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMTSLMDLTLLLARS---QPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVDFPSATLACVGTVQMCAHTHLRLGAPGPHCAHGSALPRFCGMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYSDVVGADVLDEVVTVLSDTAWDAELAVVREQRNRLCDLLGVPRPQLVPQ 500

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Human
Match: TBCD (tubulin folding cofactor D [Source:HGNC Symbol;Acc:HGNC:11581])

HSP 1 Score: 187.963 bits (476), Expect = 7.584e-53
Identity = 98/281 (34.88%), Postives = 159/281 (56.58%), Query Frame = 2

Query: 2726 SQQAVEKIDRVRNTAGKLFYDLVYM-KDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            +QQA EKIDR R  A  +F  L++     IP +P    ++ +F +     + W+AP   FP  ++LL    YRY ++LGLVVS+GG+TE T++HS ++L   +K  + D +     S  +L++F++                         + +       + ++   K EI  +KDIQK+ SGI VFC M+QF   + R+A+  L +L+ H+FP+IRK TA+ +Y++LL Y ++V  D   E++ +L +T WD ELA VRE RN++C+L  +P P+L+ +
Sbjct:    1 AQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFED-------------------------NLLNESHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCGMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYSDVVGADVLDEVVTVLSDTAWDAELAVVREQRNRLCDLLGVPRPQLVPQ 256

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Celegans
Match: tbcd-1 (Tubulin-specific chaperone D [Source:UniProtKB/Swiss-Prot;Acc:Q19493])

HSP 1 Score: 384.415 bits (986), Expect = 2.599e-113
Identity = 335/1162 (28.83%), Postives = 562/1162 (48.36%), Query Frame = 2

Query:   98 HLNEVNQLIDTLQEIIGLQNK-----EEIWEDRLQYIFNQYQAQPHLLD---PYLEXXXXXXXXXXXXXXXXERKESFVFR--LIYL--MVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFD-SANKEPIAQRILKTGKYFLM-SKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENE------EDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPK-SLADDIVEAILVL-FSRLEGFSSWH--GACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNK-----LLPFAPEYLIREVLPSLITSC-TGMDLYKRQGSIMATGELILAMESPNDIPETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDE--VIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMYEIVEEDQYSEIMNILQETIWDNE 3487
            H+ E+ +L+D L  I  L+N+      E+   R   + + YQ QP LLD   P +   L   + LI       R  + + R  L YL  +   RG KTI+RL+PH+V  L+P+L  L     +   +   R VLL+WL IV+  PFD+  FD + + + +  RI+    +++    + SQ +AA +++  L R D I      + + +    + ++K  H +    +   L L   + K   R  L      I E  + +  +  ++  L+C+   K+VQRIGL+ LK +  +W Y RG R+L   L  N   SD     SF   V++ ++ N++ + E      ++ E SE++   +  ++ +L +  T VRWSAAKG+GRI  RLP   LA  +V +I+   F  +  +SSWH  GACLALAEL  RG LLP  L +++P +  +L +++  G    G  VRDAACY  WA +R Y P  + PY+  +AS L+   LFDRQVN+RRAA+AA QE VGRQ    HGI ++ + DYFAV N   C+ +L + +A +  Y   ++ HL+  KV HWD  IRE  A +L K     L   + +Y +  +   L  SC T +  + R G ++A+G LI  + S      + +TEI  I   L          G L+R+ +C  I   S +K     +     W   L +  T   + +R+ A  A  EF+  Y  + +  I+ + K   I   ++   E+  E I       +G     I E+ +   +D  M   +   +L  +  +    +KW  AR   + +L  I  +V  + E   + I  + +  L  ++ DYT  ++GDIG  VRE++MR++   S +L +  + +    DE + +     + QQ+ E+I R R  A      LV  +     +P  + + +I++    E + + + +  F L   L     Y  +++LG+VVS GG+ E T + +++ L +  +E   +   F+        +F    + +R+     +++  I G+    +     +E++I ++D  K     +  + + +  I+    +L   +   ++R A+  ++  +  + PV+RK  A  LY+ L   E  E D   E++ +L  T W +E
Sbjct:   95 HIEEIKELVDQLPIIFKLENECDETAAEVNYLRYSRLLHLYQEQPRLLDKWIPEIVANLVDLVTLIGIDVSKPRAMTPLSRESLKYLSDLCIVRGSKTIVRLLPHQVHLLDPLLQTLEYYETSQLSDHNQRNVLLMWLWIVVKNPFDLRRFDPTGDPDNVITRIMNVALHYMKWDWNSSQASAALVIAHCLSRTDGIP-----KVLSFLSRLLDSIKTHH-ENKKLLLADLILLLAILKHVDRRVLTGHIGTIHEQLSFLYPIDEKKGGLICKCLVKVVQRIGLIALKPRTCSWSYNRGKRLLEGMLDDNEEYSDEP---SFSNKVNSNQSCNNEIDKENQWNDGDELENSEIVEFALMHVLEALSHSDTAVRWSAAKGVGRITVRLPNFDLATQVVGSIISSHFGEVAEYSSWHSHGACLALAELAHRGVLLPSLLEDIVPALELSLVFEDVMGRHQNGNQVRDAACYAVWALSRTYEPSMMAPYLQRLASALLCGALFDRQVNLRRAASAALQEMVGRQKNVSHGIPLIQSVDYFAVTNRQKCYEHLCVPVAEYSTYSAIILRHLITKKVVHWDEKIREQAAISLEKISEIRLENVSDDYYMEILDDFLKASCETRISPFLRHGYLLASGHLIKGLTSRGMDFSSKQTEIAWIPHILWPFCDMTTQPGALIRRTLCKFIQLVSASKKVLLLEKDKSEWLDVLLQLITDPREIIRSLAKTAVGEFVMTYLMNDEELIQ-KVKTRVIAAMTKCSDES--ERIG------MG----MICESLNSEAVDYEMFESLCNTILTPTSSD----AKWALARQQTVFALNRI--SVNSSTETFNR-IGQKCFETLYKAMTDYTTSANGDIGRFVREASMRAM---STIL-VDAKTEPPFLDEHVIKSA-KYMVQQSAERISRTRECACACLKSLVKCEITGRCLPHIDLLMNIYS----EPMDFISDRTVFQLKPLLDLGSEYYEQLILGIVVSAGGLAEGTQKTAKQLLLDHQREICENKPRFDHFLSTCADLFQRARKVNRIGNSFMQILPQIFGNLGIYEQCPETSESIIEMVDTMKTIAVRSSMMSRQRLSIDSLGELLNCGKKSTVYRSALTMILDTLNSQQPVLRKSAAERLYEHLCCAE--ESDD--EVLEVLATTNWQDE 1214

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Fly
Match: TBCD (gene:FBgn0027509 transcript:FBtr0077829)

HSP 1 Score: 681.019 bits (1756), Expect = 0.000e+0
Identity = 427/1207 (35.38%), Postives = 664/1207 (55.01%), Query Frame = 2

Query:   59 DEDLKYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS---------ANKEPIAQ---------RILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILE--TNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQS-ENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILA---MESPNDIPETLK------TEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSECTTHKEKFVRTAAIEAFPEFMDC-YCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIE-----LLLRTSKIESVRTSKWGEARSYALTSLIDICETV----GITNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLIS-IIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY---EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIP 3547
            DEDL    L  F  L +V ++ID ++ I     + E   ++   + ++YQ QPHLLDP+LE LL K +  I K      +    F+ +Y++ K R YK +++ MPHE+SDLE VL +L      + E W+ RY+LLLW+SI+++ PF M+  D+          N  P+           RI +  + ++ S D     AAF+ +K+  R D IK+  LE  + W + +         D  N   G L     + K GKREDLLP++  +L+  T+ Q  +   + + L  +   K++QRIGLV LK ++ +WRY+RG R L  NL  N   +    P              +QS E  E+  V + + EV++ L+ +L++    +RWSAAKGLGR+ +RLPK LAD+++ +++ + + LE   +WHGACLALAEL +RG LLP RL E++PL+++AL+YDE  G  S G ++RD+ACY+CWAFARAYNP+++KP+V  I+S L+ V +FDR+VN RRAA+AAFQE+VGR G FP GIEI TT D+++V    N +LN+S +IA F+ Y +P+I+HLV+ KV HWD  IRELTAKAL+KL  + PEY+   VLP L+     +D+  R G ++A GE+ L    +E  +D P+ +        E+  +  T   +  +RG+SG+LM+      I  CS AK++   + ++  W K +  C   K   +R  A+EAF E     YC D          + Y+      ++    E+I+  ++A LG  P +++  + ++ +D S++ + +      L+      E+++  +W EAR+ ++ +L  + +TV    GI +    KN   ++   LL +L +YTLD+ GDIGA VRE+AM SLY       I      ++   +   EI+    QQAVEKIDR R   G+L   L++ +  IP+I +H  +  IF  D  + + W     TFPLF +LL    Y  R++LGL  SIG +TE  ++++  AL + L+    + E   +L   ++++F+     +RV YPL   +D + G       +  +       I     LE+   K + K  + I  FC +LQ    + ++ ++ L V +G +   +RK  AT LY++L ++     V E+   EI+ +L ET W   L EVR +RN++C L DI  P
Sbjct:   10 DEDLPANTLEHFTELQQVLEMIDNIKSIAANTFEREF--EQYAQVLSRYQEQPHLLDPHLEELLGKLLHKIRKPDLDTGELHAAFKYLYIICKVRTYKVLVKFMPHELSDLEFVLDLLGQQNPKEFEQWETRYILLLWMSILVLNPFHMSRLDAYDTSTSAPTTNCSPVNHVQSKNTKMDRIFELIQLYVSSNDTCSSMAAFLAAKYFIRSD-IKDLYLERFLDWIMEQ------HQADTLNVKFGQLAAVAAILKHGKREDLLPYADKLLQWITSCQYKD---DNDFLKYKNYVKIIQRIGLVHLKPRIASWRYKRGTRSLATNL--NQTTAAGGEPVVL-----------EQSLEEGEEIVVPDAIEEVIEELLQALRSGGNDIRWSAAKGLGRVTNRLPKELADEVIGSVIDILNPLEPHEAWHGACLALAELAKRGLLLPHRLEELVPLLMQALFYDEMKGYMSVGQHIRDSACYMCWAFARAYNPDDVKPFVHKISSGLLTVAVFDREVNCRRAASAAFQESVGRLGNFPFGIEISTTTDFYSVGIRQNSYLNISDYIAQFEVYREPLINHLVQHKVSHWDSAIRELTAKALHKLSLWEPEYMAAVVLPQLLAKTDTIDINCRHGCVLAMGEITLTLRKLEEKSD-PQVVYLSNQRVAELNELIITFLDKNFYRGMSGDLMKSCTSSYIKNCSLAKLQATPECLVS-WQKVIDSCLITKSNAIRDGAVEAFGELCTTYYCSDSRHGENEAIINTYLTGADNDLE----EHIRMGYIAALGVLPSFMIRCHLQAILD-SLVKHSLTPLQAVLVGEMGDRENIQAYRWSEARTQSVLALTKLVKTVGYGGGIDSFAEPKNFN-KVIECLLRALQEYTLDNRGDIGAWVREAAMSSLYE------IVTTCPPDLLAPEQVHEIVVGFMQQAVEKIDRTRGLGGRLCCQLIHHQPRIPYIREHSKLLEIFPAD-ADSVLWLFADHTFPLFCELLSLPDYSKRVLLGLSASIGQLTESLIKYASSALFHFLR---SNPETVPRLCSEVVQIFEEHLLNERVTYPLLSFLDILIGSGTVESVLHDEANPFAEDIFRLLNLEVKGYKKLYKTATSISAFCQLLQVPR-LSKRILSKLSVFLGLQHVHVRKTAATKLYEALALHGDVTEVPEENMDEILTLLSETDWTQPLVEVRPLRNQLCQLMDIKPP 1172

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Zebrafish
Match: tbcd (tubulin folding cofactor D [Source:ZFIN;Acc:ZDB-GENE-060823-1])

HSP 1 Score: 826.624 bits (2134), Expect = 0.000e+0
Identity = 472/1209 (39.04%), Postives = 706/1209 (58.40%), Query Frame = 2

Query:   53 EDDEDL-KYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS-------ANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELI-----LAMESPNDIPETLKTE----IKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSEC-------TTHKEKFVRTAAIEAFPEFMDCYCFDR------DLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGI-----TNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKD-VIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETL-ISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMYEIVEEDQ--YSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            ED E L +  +L++F    E   LI +L +I       E   ++   I ++YQ QPHLLDP+LE +L+  +++I   K         F+ +Y++ K RGYK  ++L PHEVSD++PVL +L      D E W+ RY+LLLWLS+  +IPFD++  D         N+E    RIL+  K FL   D S+ AA+ ++SKF+ RPD +K K L + + W +  I       ++G   + G L+    LFK GKR+D L ++  +LE  NQ   +    +  L +L  K+VQR+GL FLK ++  WRYQRG+R L  NL  +S+     +  +  P++++V         EED+++ + +  V++ L+  LK+  T VRWS+AKG+GR+  RLPK LADD+VE++L  FS  E  ++WHG CLALAELGRRG LLP RL +V+PLI+KAL YDEK G CS G+NVRDA CYVCWAFARAY P ELKPYV  IAS+L++ T+FDR V  R+AA+AAFQENVGRQG FPHGI+I+T  DYF V N  NC+L +S++IA F+EY KP+IDHLV +K+ HWD  IREL  KAL+ L   APEY+   VLP L+   TGMDL+ R G+I+A  E+      LA ++   + + + ++    +K I   L  R Q+RG  GELMR A+C LI   S +KM F+ +P+I  W   + +        ++   + ++ AA+ A      C+ + +      D+ ++ E    Y+      +Q   +       LA LG  P +++            +  I+  L  T ++ + +     EAR  A T++  +C  VG+     +++ L ++ I  +Y  LL  ++DY+ DS GD+GA VR +AM SL   + L+  S     E+   DL   ++  ++QQA EKIDR R  AG +F  L++  D  +P IP HE + SIF  +    L W A    FP  ++LL+   Y+Y  +LGL VS+GG+TE TV+ S ++L + LK  + D     +  D +LR+F +  R DRV  PL K++D I  +  +  F  +++    + ++   K EI  +KD+QK+ S I VFC ++QF   + +K +  L++L+ H FP+IRK TA+ +Y+ LL Y+ V ED+   +++M  L +T W++++A VR  RN++C+   +P P L+ K
Sbjct:   11 EDAEVLAQACVLSEFTESTETRALISSLPDIHHDTVSREATIEKFVVIMDRYQEQPHLLDPHLEWMLNMLLEMIRSEKSPPLLVHLCFKFLYIISKVRGYKIFMQLFPHEVSDVQPVLDLLCRQDQKDTETWETRYILLLWLSMTCLIPFDLSRLDGHLSTVPGTNRESTMDRILEVAKSFLRVSDKSRDAASVLVSKFVTRPD-VKQKRLGDFLDWCLTTISQSSEMTMEGTVILDGALQSLAQLFKHGKRDDFLQYAPTVLECLNQ-KKIAESNQATLRKLGVKVVQRLGLTFLKPRLAKWRYQRGSRSLAVNLAQSSV---TESVEATKPDLESVSQ-------EEDYDIPQEVENVIEQLLLGLKDKETIVRWSSAKGIGRVTGRLPKELADDVVESVLDCFSFQETDNAWHGGCLALAELGRRGLLLPSRLSDVVPLILKALTYDEKRGACSLGSNVRDAGCYVCWAFARAYEPTELKPYVNQIASSLVIATVFDRNVTCRKAASAAFQENVGRQGTFPHGIDIITAADYFTVGNLNNCYLTISVYIAGFEEYTKPLIDHLVAMKINHWDGAIRELATKALHNLTIQAPEYMANTVLPQLLPMATGMDLHSRHGAILACAEITHALYKLAAQNNRSVTDLMSSDTIEGLKDIHQKLSDRKQYRGFGGELMRPAVCSLIEKLSLSKMPFKDEPVIAGWQWLIDDSLKNLHLFSSGVRRGIQDAAVSALAAL--CWQYYQVEPGVADVKMQEELVSQYLS----ALQSPEVLTRCGCALA-LGSLPPFMIHNK---------LQQILSGLQATCRV-AQKGESLTEARRDAATAMSQVCVAVGVCAQGRSDQVLCEDNIRPVYEALLGCMNDYSTDSRGDVGAWVRAAAMSSLMDVTLLVVAS---APELLSSDLVLRMMCCLAQQAAEKIDRYRAHAGTVFLRLLHGTDPAVPHIPHHEELLSIFPPETGNSLNWNAASQAFPHITQLLRLPQYQYHTLLGLCVSVGGLTESTVRFSSQSLFDYLKGIQQDFTMLQQFGDTLLRIFRDNLRNDRVSVPLLKMVDQILANGCFDLFTRQESHPFCVELLSLCKEEIKKSKDVQKLLSCIAVFCGLVQFPGDVRKKVLVQLLMLLCHPFPLIRKTTASQVYEMLLTYDDVIEDEQVLADVMASLSDTNWESDIATVRSHRNQLCDWLGVPKPTLVAK 1187

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Xenopus
Match: mis12 (MIS12 kinetochore complex component [Source:Xenbase;Acc:XB-GENE-1014628])

HSP 1 Score: 801.586 bits (2069), Expect = 0.000e+0
Identity = 457/1195 (38.24%), Postives = 678/1195 (56.74%), Query Frame = 2

Query:   80 ILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS-------ANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELI-----LAMESPNDIPETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSE--------CTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILR-----IYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKD-VIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISII-----DKTKLE--ICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            IL  F    E   LI +L+ +       E+   R   I ++YQ QPHLLDP+L+ +L+  +++I             F+ +Y++ K RGYK  +RL PHEV D++PVL M+S     D+E W+ RY+LLLWLS+  +IPFD++  D          ++P    IL   K +L+  D ++ AAA ++SKF+ RPD +K K + + + W +  + N     ++G   M G+L+                         N + ++  + + +L +L TKLVQRIGL FLK KV  WRYQRG+R L  NL  +S ++   NP   +P            E EE +++ E +  V++ L+  LK+  T VRWSAAKG+GR+  RLPK LADD+V ++L  FS  E  ++WHG CLALAELGRRG LLP RLP+V+PLI+KAL YDEK G CS G+NVRDAACYVCWAFARAY+P+E+ P+V +IAS L++  +FDR VN RR             G FPHGI+ILTT DYFAV N  NC+LN+S+F+A F EY KPMIDHLVE+K+ HWD  +REL+ KAL+ L P AP+Y+   VLP L+    G DL+ R G+I+A  E+      L+ +    + + L  E               GL GELMR A+C L+   S ++    G+ II  W   ++          +T ++K ++ AA+ A       Y   R         D+ ++  + ++Q +  E ++      LG  P+++L+           +  ++  L R + I S +   + E+R  AL ++  +C+TVG+  E   +  + R     +Y  LL  ++DYT DS GD+GA VRE+AM SL   + L++   Q +A++ D D  Q ++  +SQQ+ EKIDR R  AG +F +L+Y  D  +P +P  E ++ IF + Q E L W AP   FP  ++LL    YRY +++GL VS+GG+TE TV++S + L   L+  + D E  +  S  +L+VF +    DRV  PL K++D +  +  +   I  Q E +I+++       T+L    C +KDIQK++S I VFC ++QF   I +K +  L++L+ H FP IRK TA+ +Y+ LL Y ++VE +   E+M +L ++ WD +L  VRE RN +C+L  +P P L+TK
Sbjct:   22 ILESFMENQETRDLIGSLRTVWQELVSREVCTQRFVVIMDKYQEQPHLLDPHLDWMLNSLLEIIQDKASPPVLFHLAFKFLYIISKVRGYKIFLRLFPHEVVDVQPVLEMISAQDPKDHETWETRYMLLLWLSMTCLIPFDLSRLDGNIASDLGPKRKPTMDIILDVAKSYLVVSDKARDAAAVLVSKFITRPD-VKQKRMADFLDWTLSTLSNASYLTMEGTIAMDGMLQALV----------------------NPLIHIAKDNQTVLRKLGTKLVQRIGLTFLKTKVANWRYQRGSRCLAANLLQSSSDTQKSNPA--LPG-----------EEEEAYDIPEEIENVVEQLLVGLKDKDTIVRWSAAKGIGRLTGRLPKELADDVVGSVLDCFSFQETNNAWHGGCLALAELGRRGLLLPSRLPDVVPLILKALVYDEKRGACSVGSNVRDAACYVCWAFARAYDPQEMNPFVNEIASALVIAAVFDRDVNCRR----------AASGTFPHGIDILTTADYFAVGNRANCYLNISVFVAGFPEYTKPMIDHLVEMKINHWDGVVRELSTKALHNLTPTAPQYMTETVLPRLLPLAIGTDLHTRHGAILACAEITHAVYKLSAQCNRPLSDYLNNET--------------GLGGELMRPAVCCLVEKLSLSQFPHPGEDIIGGWLWLITNSLKSLHLFSSTARQK-IKEAAVSALSTLCQEYYKGR----AAAAHDDLVKQFTSELQSSE-EMVRCGFSLALGALPQFLLK---------GRLQQVLGGLRRVTSI-SGKDVGFAESRRDALRAIAQVCQTVGVRAEGSAEEAVCRENMALVYNTLLNCMNDYTTDSRGDVGAWVREAAMASLQDVTLLVA---QTEADLLDPDFVQRMMCALSQQSAEKIDRYRAFAGSVFLNLLYFSDPPVPHVPHREELERIFPRTQAESLNWNAPSQAFPRITQLLGLATYRYYVLMGLTVSVGGLTESTVRYSAQGLFEYLRAIQNDTEQMDAFSASLLQVFRDNQHIDRVSIPLLKMLDQMLANGCFD--IYTQEEKIITLMRYVSPTATRLPPTYCPSKDIQKLRSSIAVFCGLIQFPGDIRKKVLFQLLLLVCHPFPRIRKTTASEVYEMLLTYDDVVEPEILDEVMAVLSDSTWDADLPTVREQRNHLCDLLKVPRPTLVTK 1135

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Xenopus
Match: mis12 (MIS12 kinetochore complex component [Source:Xenbase;Acc:XB-GENE-1014628])

HSP 1 Score: 777.704 bits (2007), Expect = 0.000e+0
Identity = 441/1152 (38.28%), Postives = 660/1152 (57.29%), Query Frame = 2

Query:  191 IFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS-------ANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAIL--VLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILAMESPNDIPETLKTEIKSICSTLDKRMQFRGLSGELMRKAM--CHLIWCCSKAKMR------FQGDPIIDLWYKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILR-----IYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKD-VIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISIIDKTKLEI----CTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            I ++YQ QPHLLDP+L+ +L+  +++I             F+ +Y++ K RGYK  +RL PHEV D++PVL M+S     D+E W+ RY+LLLWLS+  +IPFD++  D          ++P    IL   K +L+  D ++ AAA ++SKF+ RPD +K K + + + W +  + N     ++G   M G+L+    LFK GKRED LP+++++L   +   N+    + +L +L TKLVQRIGL FLK KV  WRYQRG+R L  NL  +S ++   NP   +P            E EE +++ E +  V++ L+  LK+  T VRWSAAKG+GR+  RLPK LADD+V ++L        E  ++WHG CLALAELGRRG LLP RLP+V+PLI+KAL YDEK G CS G+NVRDAACYVCWAFARAY+P+E+ P+V +IAS L++  +FDR VN RR             G FPHGI+ILTT DYFAV N  NC+LN+S+F+A F EY KPMIDHLVE+K+ HWD  +REL+ KAL+ L P AP+Y+   VLP L+    G DL+ R G+I+A  E+  A+   +      +  + S C        F G    L+  ++   HL    ++ K++      ++G P + +W                        +F              +++D+ ++  + ++Q +  E ++      LG  P+++L+           +  ++  L R + I S +   + E+R  AL ++  +C+TVG+  E   +  + R     +Y  LL  ++DYT DS GD+GA VRE+AM SL   + L++ +        + DL Q ++  +SQQ+ EKIDR R  AG +F +L+Y  D  +P +P  E ++ IF + Q E L W AP   FP  ++LL    YRY +++GL VS+GG+TE TV++S + L   L+  + D E  +  S  +L+VF +    DRV  PL K++D +  +       G +  TL+  +  T   +    C +KDIQK++S I VFC ++QF   I +K +  L++L+ H FP IRK TA+ +Y+ LL Y ++VE +   E+M +L ++ WD +L  VRE RN +C+L  +P P L+TK
Sbjct:   19 IMDKYQEQPHLLDPHLDWMLNSLLEIIQDKASPPVLFHLAFKFLYIISKVRGYKIFLRLFPHEVVDVQPVLEMISAQDPKDHETWETRYMLLLWLSMTCLIPFDLSRLDGNIASDLGPKRKPTMDIILDVAKSYLVVSDKARDAAAVLVSKFITRPD-VKQKRMADFLDWTLSTLSNASYLTMEGTIAMDGMLQALAQLFKHGKREDCLPYASIVLTCLDNC-NLCDSNQTVLRKLGTKLVQRIGLTFLKTKVANWRYQRGSRCLAANLLQSSSDTQKSNPA--LPG-----------EEEEAYDIPEEIENVVEQLLVGLKDKDTIVRWSAAKGIGRLTGRLPKELADDVVGSVLDCCFVGFQETNNAWHGGCLALAELGRRGLLLPSRLPDVVPLILKALVYDEKRGACSVGSNVRDAACYVCWAFARAYDPQEMNPFVNEIASALVIAAVFDRDVNCRR----------AASGTFPHGIDILTTADYFAVGNRANCYLNISVFVAGFPEYTKPMIDHLVEMKINHWDGVVRELSTKALHNLTPTAPQYMTETVLPRLLPLAIGTDLHTRHGAILACAEITHAVYKLSAQYSINRRGLYSRC--------FAGGWLWLITNSLKSLHLFSSTARQKIKVPFLCAYRGIPSLGIW------------------------DF--------------KWRDDLVKQFTSELQSSE-EMVRCGFSLALGALPQFLLKGR---------LQQVLGGLRRVTSI-SGKDVGFAESRRDALRAIAQVCQTVGVRAEGSAEEAVCRENMALVYNTLLNCMNDYTTDSRGDVGAWVREAAMASLQDVTLLVAQT--------EADLVQRMMCALSQQSAEKIDRYRAFAGSVFLNLLYFSDPPVPHVPHREELERIFPRTQAESLNWNAPSQAFPRITQLLGLATYRYYVLMGLTVSVGGLTESTVRYSAQGLFEYLRAIQNDTEQMDAFSASLLQVFRDNQHIDRVSIPLLKMLDQMLAN-------GLRIITLMRYVSPTATRLPPTYCPSKDIQKLRSSIAVFCGLIQFPGDIRKKVLFQLLLLVCHPFPRIRKTTASEVYEMLLTYDDVVEPEILDEVMAVLSDSTWDADLPTVREQRNHLCDLLKVPRPTLVTK 1073

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Xenopus
Match: mis12 (MIS12 kinetochore complex component [Source:Xenbase;Acc:XB-GENE-1014628])

HSP 1 Score: 775.393 bits (2001), Expect = 0.000e+0
Identity = 442/1131 (39.08%), Postives = 650/1131 (57.47%), Query Frame = 2

Query:   80 ILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS-------ANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELI-----LAMESPNDIPETLKTE----IKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSE--------CTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILR-----IYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKD-VIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKH 3382
            IL  F    E   LI +L+ +       E+   R   I ++YQ QPHLLDP+L+ +L+  +++I             F+ +Y++ K RGYK  +RL PHEV D++PVL M+S     D+E W+ RY+LLLWLS+  +IPFD++  D          ++P    IL   K +L+  D ++ AAA ++SKF+ RPD +K K + + + W +  + N     ++G   M G+L+    LFK GKRED LP+++++L   +   N+    + +L +L TKLVQRIGL FLK KV  WRYQRG+R L  NL  +S ++   NP   +P            E EE +++ E +  V++ L+  LK+  T VRWSAAKG+GR+  RLPK LADD+V ++L  FS  E  ++WHG CLALAELGRRG LLP RLP+V+PLI+KAL YDEK G CS G+NVRDAACYVCWAFARAY+P+E+ P+V +IAS L++  +FDR VN RRAA+AAFQENVGRQG FPHGI+ILTT DYFAV N  NC+LN+S+F+A F EY KPMIDHLVE+K+ HWD  +REL+ KAL+ L P AP+Y+   VLP L+    G DL+ R G+I+A  E+      L+ +    + + L  E    + +I   L +R  +RGL GELMR A+C L+   S ++    G+ II  W   ++          +T ++K ++ AA+ A       Y   R         D+ ++  + ++Q +  E ++      LG  P+++L+           +  ++  L R + I S +   + E+R  AL ++  +C+TVG+  E   +  + R     +Y  LL  ++DYT DS GD+GA VRE+AM SL   + L++   Q +A++ D D  Q ++  +SQQ+ EKIDR R  AG +F +L+Y  D  +P +P  E ++ IF + Q E L W AP   FP  ++LL    YRY +++GL VS+GG+TE TV++S + L   L+  + D E  +  S  +L+VF +    DRV  PL K++D +  +  +  +   +     S  D   L+     +IQ        +C +L+ D V  R      +       P I K+
Sbjct:   76 ILESFMENQETRDLIGSLRTVWQELVSREVCTQRFVVIMDKYQEQPHLLDPHLDWMLNSLLEIIQDKASPPVLFHLAFKFLYIISKVRGYKIFLRLFPHEVVDVQPVLEMISAQDPKDHETWETRYMLLLWLSMTCLIPFDLSRLDGNIASDLGPKRKPTMDIILDVAKSYLVVSDKARDAAAVLVSKFITRPD-VKQKRMADFLDWTLSTLSNASYLTMEGTIAMDGMLQALAQLFKHGKREDCLPYASIVLTCLDNC-NLCDSNQTVLRKLGTKLVQRIGLTFLKTKVANWRYQRGSRCLAANLLQSSSDTQKSNPA--LPG-----------EEEEAYDIPEEIENVVEQLLVGLKDKDTIVRWSAAKGIGRLTGRLPKELADDVVGSVLDCFSFQETNNAWHGGCLALAELGRRGLLLPSRLPDVVPLILKALVYDEKRGACSVGSNVRDAACYVCWAFARAYDPQEMNPFVNEIASALVIAAVFDRDVNCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNRANCYLNISVFVAGFPEYTKPMIDHLVEMKINHWDGVVRELSTKALHNLTPTAPQYMTETVLPRLLPLAIGTDLHTRHGAILACAEITHAVYKLSAQCNRPLSDYLNNETLAGLAAIHPKLQERQLYRGLGGELMRPAVCCLVEKLSLSQFPHPGEDIIGGWLWLITNSLKSLHLFSSTARQK-IKEAAVSALSTLCQEYYKGRAAAAH----DDLVKQFTSELQSSE-EMVRCGFSLALGALPQFLLK---------GRLQQVLGGLRRVTSI-SGKDVGFAESRRDALRAIAQVCQTVGVRAEGSAEEAVCRENMALVYNTLLNCMNDYTTDSRGDVGAWVREAAMASLQDVTLLVA---QTEADLLDPDFVQRMMCALSQQSAEKIDRYRAFAGSVFLNLLYFSDPPVPHVPHREELERIFPRTQAESLNWNAPSQAFPRITQLLGLATYRYYVLMGLTVSVGGLTESTVRYSAQGLFEYLRAIQNDTEQMDAFSASLLQVFRDNQHIDRVSIPLLKMLDQMLANGCFDIYTQEENHPFAS--DLLSLQRHPEAEIQ--------YCCVLRPDPVPRRYPKEGSVSAAASGLPPIPKN 1162

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Xenopus
Match: mis12 (MIS12 kinetochore complex component [Source:Xenbase;Acc:XB-GENE-1014628])

HSP 1 Score: 772.311 bits (1993), Expect = 0.000e+0
Identity = 448/1191 (37.62%), Postives = 668/1191 (56.09%), Query Frame = 2

Query:   80 ILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS-------ANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILAMESPNDIPETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMR------FQGDPIIDLW---YKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILR-----IYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKD-VIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISII-----DKTKLE--ICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            IL  F    E   LI +L+ +       E+   R   I ++YQ QPHLLDP+L+ +L+  +++I             F+ +Y++ K RGYK  +RL PHEV D++PVL M+S     D+E W+ RY+LLLWLS+  +IPFD++  D          ++P    IL   K +L+  D ++ AAA ++SKF+ RPD +K K + + + W +  + N     ++G   M G+L+                         N + ++  + + +L +L TKLVQRIGL FLK KV  WRYQRG+R L  NL  +S ++   NP   +P            E EE +++ E +  V++ L+  LK+  T VRWSAAKG+GR+  RLPK LADD+V ++L  FS  E  ++WHG CLALAELGRRG LLP RLP+V+PLI+KAL YDEK G CS G+NVRDAACYVCWAFARAY+P+E+ P+V +IAS L++  +FDR VN RR             G FPHGI+ILTT DYFAV N  NC+LN+S+F+A F EY KPMIDHLVE+K+ HWD  +REL+ KAL+ L P AP+Y+   VLP L+    G DL+ R G+I+A  E+  A+            ++ + C+    R   R   G    +++ HL    ++ K++      ++G P + +W   ++ LS      ++F  T+ +++  E + C                                     LA LG  P+++L+           +  ++  L R + I S +   + E+R  AL ++  +C+TVG+  E   +  + R     +Y  LL  ++DYT DS GD+GA VRE+AM SL   + L++   Q +A++ D D  Q ++  +SQQ+ EKIDR R  AG +F +L+Y  D  +P +P  E ++ IF + Q E L W AP   FP  ++LL    YRY +++GL VS+GG+TE TV++S + L   L+  + D E  +  S  +L+VF +    DRV  PL K++D +  +  +   I  Q E +I+++       T+L    C +KDIQK++S I VFC ++QF   I +K +  L++L+ H FP IRK TA+ +Y+ LL Y ++VE +   E+M +L ++ WD +L  VRE RN +C+L  +P P L+TK
Sbjct:   74 ILESFMENQETRDLIGSLRTVWQELVSREVCTQRFVVIMDKYQEQPHLLDPHLDWMLNSLLEIIQDKASPPVLFHLAFKFLYIISKVRGYKIFLRLFPHEVVDVQPVLEMISAQDPKDHETWETRYMLLLWLSMTCLIPFDLSRLDGNIASDLGPKRKPTMDIILDVAKSYLVVSDKARDAAAVLVSKFITRPD-VKQKRMADFLDWTLSTLSNASYLTMEGTIAMDGMLQALV----------------------NPLIHIAKDNQTVLRKLGTKLVQRIGLTFLKTKVANWRYQRGSRCLAANLLQSSSDTQKSNPA--LPG-----------EEEEAYDIPEEIENVVEQLLVGLKDKDTIVRWSAAKGIGRLTGRLPKELADDVVGSVLDCFSFQETNNAWHGGCLALAELGRRGLLLPSRLPDVVPLILKALVYDEKRGACSVGSNVRDAACYVCWAFARAYDPQEMNPFVNEIASALVIAAVFDRDVNCRR----------AASGTFPHGIDILTTADYFAVGNRANCYLNISVFVAGFPEYTKPMIDHLVEMKINHWDGVVRELSTKALHNLTPTAPQYMTETVLPRLLPLAIGTDLHTRHGAILACAEITHAV-----------YKLSAQCN----RPLIRKTPGPEGSESL-HLFSSTARQKIKVPFLCAYRGIPSLGIWDFKWRGLSPINDLVKQF--TSELQSSEEMVRC----------------------------------GFSLA-LGALPQFLLK---------GRLQQVLGGLRRVTSI-SGKDVGFAESRRDALRAIAQVCQTVGVRAEGSAEEAVCRENMALVYNTLLNCMNDYTTDSRGDVGAWVREAAMASLQDVTLLVA---QTEADLLDPDFVQRMMCALSQQSAEKIDRYRAFAGSVFLNLLYFSDPPVPHVPHREELERIFPRTQAESLNWNAPSQAFPRITQLLGLATYRYYVLMGLTVSVGGLTESTVRYSAQGLFEYLRAIQNDTEQMDAFSASLLQVFRDNQHIDRVSIPLLKMLDQMLANGCFD--IYTQEEKIITLMRYVSPTATRLPPTYCPSKDIQKLRSSIAVFCGLIQFPGDIRKKVLFQLLLLVCHPFPRIRKTTASEVYEMLLTYDDVVEPEILDEVMAVLSDSTWDADLPTVREQRNHLCDLLKVPRPTLVTK 1150

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Xenopus
Match: mis12 (MIS12 kinetochore complex component [Source:Xenbase;Acc:XB-GENE-1014628])

HSP 1 Score: 771.155 bits (1990), Expect = 0.000e+0
Identity = 446/1195 (37.32%), Postives = 660/1195 (55.23%), Query Frame = 2

Query:   80 ILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS-------ANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELI-----LAMESPNDIPETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSE--------CTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILR-----IYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKD-VIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISII-----DKTKLE--ICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            IL  F    E   LI +L+ +       E+   R   I ++YQ QPHLLDP+L+ +L+  +++I             F+ +Y++ K RGYK  +RL PHEV D++PVL M+S     D+E W+ RY+LLLWLS+  +IPFD++  D          ++P    IL   K +L+  D ++ AAA ++SKF+ RPD +K K + + + W +  + N     ++G   M G+L+                         N + ++  + + +L +L TKLVQRIGL FLK KV  WRYQRG+R L  NL  +S ++   NP   +P            E EE +++ E +  V++ L+  LK+  T VRWSAAKG+GR+  RLPK LADD+V ++L  FS  E  ++WHG CLALAELGRRG LLP RLP+V+PLI+KAL YDEK G CS G+NVRDAACYVCWAFARAY+P+E+ P+V +IAS L++  +FDR VN RR             G FPHGI+ILTT DYFAV N  NC+LN+S+F+A F EY KPMIDHLVE+K+ HWD  +REL+ KAL+ L P AP+Y+   VLP L+    G DL+ R G+I+A  E+      L+ +    + + L  E               GL GELMR A+C L+   S ++    G+ II  W   ++          +T ++K ++ AA+ A       Y   R         D+ ++  + ++Q +  E ++      LG  P+++L+           +  ++  L R + I S +   + E+R  AL ++  +C+TVG+  E   +  + R     +Y  LL  ++DYT DS GD+GA V                               Q ++  +SQQ+ EKIDR R  AG +F +L+Y  D  +P +P  E ++ IF + Q E L W AP   FP  ++LL    YRY +++GL VS+GG+TE TV++S + L   L+  + D E  +  S  +L+VF +    DRV  PL K++D +  +  +   I  Q E +I+++       T+L    C +KDIQK++S I VFC ++QF   I +K +  L++L+ H FP IRK TA+ +Y+ LL Y ++VE +   E+M +L ++ WD +L  VRE RN +C+L  +P P L+TK
Sbjct:   22 ILESFMENQETRDLIGSLRTVWQELVSREVCTQRFVVIMDKYQEQPHLLDPHLDWMLNSLLEIIQDKASPPVLFHLAFKFLYIISKVRGYKIFLRLFPHEVVDVQPVLEMISAQDPKDHETWETRYMLLLWLSMTCLIPFDLSRLDGNIASDLGPKRKPTMDIILDVAKSYLVVSDKARDAAAVLVSKFITRPD-VKQKRMADFLDWTLSTLSNASYLTMEGTIAMDGMLQALV----------------------NPLIHIAKDNQTVLRKLGTKLVQRIGLTFLKTKVANWRYQRGSRCLAANLLQSSSDTQKSNPA--LPG-----------EEEEAYDIPEEIENVVEQLLVGLKDKDTIVRWSAAKGIGRLTGRLPKELADDVVGSVLDCFSFQETNNAWHGGCLALAELGRRGLLLPSRLPDVVPLILKALVYDEKRGACSVGSNVRDAACYVCWAFARAYDPQEMNPFVNEIASALVIAAVFDRDVNCRR----------AASGTFPHGIDILTTADYFAVGNRANCYLNISVFVAGFPEYTKPMIDHLVEMKINHWDGVVRELSTKALHNLTPTAPQYMTETVLPRLLPLAIGTDLHTRHGAILACAEITHAVYKLSAQCNRPLSDYLNNET--------------GLGGELMRPAVCCLVEKLSLSQFPHPGEDIIGGWLWLITNSLKSLHLFSSTARQK-IKEAAVSALSTLCQEYYKGR----AAAAHDDLVKQFTSELQSSE-EMVRCGFSLALGALPQFLLK---------GRLQQVLGGLRRVTSI-SGKDVGFAESRRDALRAIAQVCQTVGVRAEGSAEEAVCRENMALVYNTLLNCMNDYTTDSRGDVGACV-------------------------------QRMMCALSQQSAEKIDRYRAFAGSVFLNLLYFSDPPVPHVPHREELERIFPRTQAESLNWNAPSQAFPRITQLLGLATYRYYVLMGLTVSVGGLTESTVRYSAQGLFEYLRAIQNDTEQMDAFSASLLQVFRDNQHIDRVSIPLLKMLDQMLANGCFD--IYTQEEKIITLMRYVSPTATRLPPTYCPSKDIQKLRSSIAVFCGLIQFPGDIRKKVLFQLLLLVCHPFPRIRKTTASEVYEMLLTYDDVVEPEILDEVMAVLSDSTWDADLPTVREQRNHLCDLLKVPRPTLVTK 1107

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Mouse
Match: Tbcd (tubulin-specific chaperone d [Source:MGI Symbol;Acc:MGI:1919686])

HSP 1 Score: 834.328 bits (2154), Expect = 0.000e+0
Identity = 469/1202 (39.02%), Postives = 702/1202 (58.40%), Query Frame = 2

Query:   56 DDEDLKYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS-------ANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKW--EREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELI-----LAMESPNDIPETLKTE----IKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSE-------CTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGIT-----NEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKD-VIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETL-ISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            DD  ++   L  F    E   L+ +L  +   +   E+ E+R + I ++YQ QPHLLDP+LE +++  + L+     +       F+ +Y++ K RGYK  +RL PHEV++++PVL M +     D+E W+ RY+LLLWLS+  +IPFD +  D          + P   RIL+  + +L+  D ++ AAA ++SKF+ RPD +K + +   + W++  + +   + I+G   M G+L+    +FK GKRED LP++  +L+    +D  +        L +L  KLVQR+GL FLK KV TWRYQRG R L  NL   +    ++   S     D++      S+ +ED++V E +  V++ L+  LK+  T VRWSAAKG+GR+  RLP+ LADD+V ++L  FS  E   +WHG CLALAELGRRG LLP RL EV+ +I+KAL YDEK G CS GANVRDAACYVCWAFARAY P+EL P+V  I+S L++  +FDR VN RRAA+AAFQENVGRQG FPHGI+ILTT DYFAV N +NCFL +S+FIA F+EY KPMIDHLV +K+ HWD  IREL+AKAL+ L P  PEY+   V P+L+      DL+ R G+I+A  E+      LA +S   + + L  +    +K I   L  R  +RGL GELMR+A+C LI   S ++M F+GD  ++ W   +++        ++H  + ++  A+ A       Y         +      I     ++Q    E  +    + LG  P ++L  +         +  ++  L R + I     S + EAR   L ++  IC+TVG+      +E + K  I  +YA LL  + DYT DS GD+GA VRE+AM SL     LL+   + +  + +  + + ++  ++QQA EKIDR R  A ++F  L++     IP +P  + ++S+F +     + W AP   FPL ++LL    YRY ++LGL VS+GG+TE TV+HS ++L   +K  + D +     S+ +L+VF++    DRV   L K++D +  +  +  F   +     + ++   K EI  +KDIQK++S I V C M+QF+  + +K +  L +L+GH FPVIRK TA+ +Y+ +L Y ++V+ +   E+M++L +T WD EL  VRE RN++C+L  +P P+L+ K
Sbjct:   18 DDALVRASALEAFGESAETRALLRSLPAVHRERASREVAEERFRVIMDKYQEQPHLLDPHLEWMMNSLLDLVQDETSLPDLVHLAFKFLYIITKVRGYKVFLRLFPHEVANVQPVLDMFTGQNPKDHETWETRYMLLLWLSVTCLIPFDFSRLDGNLSTQTGETRVPTMDRILQIAESYLVVSDKARDAAAVLVSKFITRPD-VKQRKMASFLDWSLCTLAHSSFQTIEGVITMDGMLQALAQIFKHGKREDCLPYANTVLQC---LDGCRLPESSHTSLRKLGVKLVQRLGLTFLKPKVATWRYQRGCRSLAANLKLCAPGKSDQKLLS-----DSL-----TSDGDEDYDVPEGVETVIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRELADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLSEVVTVILKALTYDEKRGACSVGANVRDAACYVCWAFARAYEPQELTPFVTAISSALVIAAVFDRNVNCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNISNCFLIISVFIAGFQEYTKPMIDHLVSMKINHWDGAIRELSAKALHNLTPQVPEYIAMHVFPALLLMTQSPDLHTRHGAILACAEVTYALYKLATQSNRLVTDYLDEKAVQSLKQIHQQLCDRHLYRGLGGELMRQAVCILIEKLSLSRMPFKGDATVEGWQWLINDTLRSLHLVSSHSRQQIKEVAVSALTALCSEYYVKEPGEAGSSIAKELIPQYLAELQSPE-EMARCGFSSALGALPGFLLRGH---------LQQVLSGLRRVTCISPNDVS-FAEARRDGLKAISRICQTVGVNTRGPPDEVICKENISEVYAALLGCMSDYTTDSRGDVGAWVREAAMTSLMDLMLLLA---RTEPVLIEAHICERVMCCVAQQASEKIDRFRAHAARVFLTLLHFDSPPIPHVPHRQELESLFPRSDVATVNWNAPSQAFPLITQLLGLPTYRYHVLLGLAVSVGGLTESTVRHSTQSLFEYMKGIQKDAQVLQSFSETLLKVFEDNLLNDRVSVSLLKMLDQLLANGCFDIFTAEENHPFCVKLLTLCKEEIKKSKDIQKLRSSIAVLCGMVQFNGDVRKKILLQLFLLLGHPFPVIRKSTASQVYEMVLTYSDLVDAEVLDEVMSVLSDTAWDAELPVVREQRNRLCDLLGVPRPQLVPK 1191

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Mouse
Match: Tbcd (tubulin-specific chaperone d [Source:MGI Symbol;Acc:MGI:1919686])

HSP 1 Score: 76.6406 bits (187), Expect = 1.245e-16
Identity = 34/56 (60.71%), Postives = 41/56 (73.21%), Query Frame = 2

Query: 1175 LGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPE 1342
            +GR+  RLP+ LADD+V ++L  FS  E   +WHG CLALAELGRRG LLP RL E
Sbjct:    2 IGRMAGRLPRELADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLSE 57

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Mouse
Match: Tbcd (tubulin-specific chaperone d [Source:MGI Symbol;Acc:MGI:1919686])

HSP 1 Score: 67.0106 bits (162), Expect = 4.250e-13
Identity = 37/80 (46.25%), Postives = 47/80 (58.75%), Query Frame = 2

Query:  743 LLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKW--EREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNL 976
            +L     +FK GKRED LP++  +L+    +D  +        L +L  KLVQR+GL FLK KV TWRYQRG R L  NL
Sbjct:    2 MLHTVAQIFKHGKREDCLPYANTVLQC---LDGCRLPESSHTSLRKLGVKLVQRLGLTFLKPKVATWRYQRGCRSLAANL 78

[Close]

BLAST of Tubulin-specific chaperone D vs. UniProt/SwissProt
Match: sp|Q28205|TBCD_BOVIN (Tubulin-specific chaperone D OS=Bos taurus OX=9913 GN=TBCD PE=1 SV=1)

HSP 1 Score: 838.951 bits (2166), Expect = 0.000e+0
Identity = 474/1204 (39.37%), Postives = 701/1204 (58.22%), Query Frame = 2

Query:   47 AKEDDEDLKYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDSANKEPIAQR------ILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKW--EREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGEL-----ILAMESPNDIPETLKTE----IKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLW-------YKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDI-DLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGI-----TNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYM-KDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETL-ISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMYEIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            A ED        L  F    E  +L+  L  ++  ++  E   +R + I ++YQ QPHLLDP+LE +L+  ++ +             F+ +Y++ K RGYKT +RL PHEV+D++PVL M ++    D+E W+ RY+LLLWLS+  +IPFD +  D    +P  +R      IL+  + +L+  D ++ AAA ++SKF+ RPD +K K +   + W++  +     + I+G   M G L+    +FK GKRED LP++  +L+    +D+ +     + LL +L  KLVQR+GL FLK +V  WRYQRG R L     + S++   +NP   V   +T +     S+ ++D  V E +  V++ L+  LK+  T VRWSAAKG+GR+  RLPK LADD+  ++L  FS  E  S+WHG CLALAELGRRG LLP RL +V+P+I++AL Y+EK G CS G+NVRDAACYVCWAFARAY P+ELKP+V  I+S L++ T+FDR VN RRAA+AAFQENVGRQG FPHGI+ILTT DYFAV N +NCFL +S+FIA F EY +PMI+HLV +KVGHWD  IREL+AKAL  L   APE+  REV P L++     DL+ R G+++A  E+      LA +    + + L  +    +K I   L  R  +RGL GELMR+A+C LI   + +KM F+GD +ID W        K L   ++H  + ++ AA+ A       Y            ++  ++    ++Q    E  +      LG  P + L+   +  +  L  +T+I           S +   + EAR  AL ++  IC+TVG+      +E + +  + +IY  LL  L DYT DS GD+GA VRE+AM SL   + LL    + + E+ +  L Q+++  ++QQA EKIDR R  A ++F  L++     IP +P    ++ +F +     + W AP   FP  ++LL   AYRY ++LGL VS+GG+TE TV++S + L   +KE + D          +L+VF++    DRV  PL K +D +  +  +  F  ++     + ++   K EI  +KD+QK++S I VFC ++QF   + RK +  L +L+ H FPVIRK+TA+ +Y+ +L Y++V      E+M +L  T WD EL  VR  RN++C+L  +P P+L+ K
Sbjct:   23 AGEDAALACGAALESFGESAETRELLGHLPAVLADRSAREGALERFRVIMDKYQEQPHLLDPHLEWMLNLLLEFVQNKTSPADLVHLAFKFLYIISKVRGYKTFLRLFPHEVADVQPVLDMFTNQNPKDHETWETRYMLLLWLSVTCLIPFDFSRLDGNLSQPGQERASTMDRILQVAESYLVVSDKARDAAAVLVSKFVTRPD-VKQKKMASFLDWSLCTLARSSFQTIEGVIAMDGTLQALAQIFKHGKREDCLPYAATVLQC---LDSCRLPDSNQTLLRKLGVKLVQRLGLTFLKPQVAKWRYQRGCRSL-----AESLQHSIQNPREPVTQAETPD-----SDGQDD--VPEEVESVIEQLLVGLKDKDTIVRWSAAKGIGRMAGRLPKELADDVTGSVLDCFSFQETDSAWHGGCLALAELGRRGLLLPSRLSDVVPVILRALTYEEKRGACSVGSNVRDAACYVCWAFARAYEPQELKPFVAAISSALVIATVFDRDVNCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNRSNCFLVISMFIAGFPEYTQPMIEHLVTMKVGHWDGTIRELSAKALRNLAQRAPEHTAREVFPRLLSMTQSPDLHTRHGAVLACAEVARSLHTLATQQGRPVSDFLDEKAMHGLKQIHQQLYDRQLYRGLGGELMRQAVCILIENVALSKMPFRGDAVIDGWQWLINDTLKNLHLISSHSRQHIKEAAVSALAALCSEYHAQEPGEAEAAAQEELVKLYLAELQSPE-EMTRCGCALALGALPAFFLKGRLRQVLAGLRAVTHI-----------SPKDVSFAEARRDALKAISRICQTVGVRAEGPPDEAVCRENVSQIYCTLLDCLKDYTTDSRGDVGAWVREAAMTSLMDLTLLLG---RNQPELIEAPLCQQLMCCLAQQASEKIDRFRAHAARVFLALLHADSPAIPHVPARPELERLFPRAAVASVNWGAPSQAFPRMARLLGLPAYRYHVLLGLAVSVGGLTESTVRYSTQGLFEYMKEIQNDPAALEDFGGTLLQVFEDNLLNDRVSVPLLKTLDQMLANGCFDIFTAQENHPFCVKLLALCKEEIKKSKDVQKLRSSIAVFCGLVQFPGDVRRKVLLQLFLLLCHPFPVIRKNTASQVYEMVLTYDVVPTAVLDEVMAVLSSTAWDAELPVVRAQRNRLCDLLGVPRPQLVPK 1195

[Close]

BLAST of Tubulin-specific chaperone D vs. UniProt/SwissProt
Match: sp|Q8BYA0|TBCD_MOUSE (Tubulin-specific chaperone D OS=Mus musculus OX=10090 GN=Tbcd PE=1 SV=1)

HSP 1 Score: 834.328 bits (2154), Expect = 0.000e+0
Identity = 469/1202 (39.02%), Postives = 702/1202 (58.40%), Query Frame = 2

Query:   56 DDEDLKYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS-------ANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKW--EREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELI-----LAMESPNDIPETLKTE----IKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSE-------CTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGIT-----NEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKD-VIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETL-ISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            DD  ++   L  F    E   L+ +L  +   +   E+ E+R + I ++YQ QPHLLDP+LE +++  + L+     +       F+ +Y++ K RGYK  +RL PHEV++++PVL M +     D+E W+ RY+LLLWLS+  +IPFD +  D          + P   RIL+  + +L+  D ++ AAA ++SKF+ RPD +K + +   + W++  + +   + I+G   M G+L+    +FK GKRED LP++  +L+    +D  +        L +L  KLVQR+GL FLK KV TWRYQRG R L  NL   +    ++   S     D++      S+ +ED++V E +  V++ L+  LK+  T VRWSAAKG+GR+  RLP+ LADD+V ++L  FS  E   +WHG CLALAELGRRG LLP RL EV+ +I+KAL YDEK G CS GANVRDAACYVCWAFARAY P+EL P+V  I+S L++  +FDR VN RRAA+AAFQENVGRQG FPHGI+ILTT DYFAV N +NCFL +S+FIA F+EY KPMIDHLV +K+ HWD  IREL+AKAL+ L P  PEY+   V P+L+      DL+ R G+I+A  E+      LA +S   + + L  +    +K I   L  R  +RGL GELMR+A+C LI   S ++M F+GD  ++ W   +++        ++H  + ++  A+ A       Y         +      I     ++Q    E  +    + LG  P ++L  +         +  ++  L R + I     S + EAR   L ++  IC+TVG+      +E + K  I  +YA LL  + DYT DS GD+GA VRE+AM SL     LL+   + +  + +  + + ++  ++QQA EKIDR R  A ++F  L++     IP +P  + ++S+F +     + W AP   FPL ++LL    YRY ++LGL VS+GG+TE TV+HS ++L   +K  + D +     S+ +L+VF++    DRV   L K++D +  +  +  F   +     + ++   K EI  +KDIQK++S I V C M+QF+  + +K +  L +L+GH FPVIRK TA+ +Y+ +L Y ++V+ +   E+M++L +T WD EL  VRE RN++C+L  +P P+L+ K
Sbjct:   18 DDALVRASALEAFGESAETRALLRSLPAVHRERASREVAEERFRVIMDKYQEQPHLLDPHLEWMMNSLLDLVQDETSLPDLVHLAFKFLYIITKVRGYKVFLRLFPHEVANVQPVLDMFTGQNPKDHETWETRYMLLLWLSVTCLIPFDFSRLDGNLSTQTGETRVPTMDRILQIAESYLVVSDKARDAAAVLVSKFITRPD-VKQRKMASFLDWSLCTLAHSSFQTIEGVITMDGMLQALAQIFKHGKREDCLPYANTVLQC---LDGCRLPESSHTSLRKLGVKLVQRLGLTFLKPKVATWRYQRGCRSLAANLKLCAPGKSDQKLLS-----DSL-----TSDGDEDYDVPEGVETVIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRELADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLSEVVTVILKALTYDEKRGACSVGANVRDAACYVCWAFARAYEPQELTPFVTAISSALVIAAVFDRNVNCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNISNCFLIISVFIAGFQEYTKPMIDHLVSMKINHWDGAIRELSAKALHNLTPQVPEYIAMHVFPALLLMTQSPDLHTRHGAILACAEVTYALYKLATQSNRLVTDYLDEKAVQSLKQIHQQLCDRHLYRGLGGELMRQAVCILIEKLSLSRMPFKGDATVEGWQWLINDTLRSLHLVSSHSRQQIKEVAVSALTALCSEYYVKEPGEAGSSIAKELIPQYLAELQSPE-EMARCGFSSALGALPGFLLRGH---------LQQVLSGLRRVTCISPNDVS-FAEARRDGLKAISRICQTVGVNTRGPPDEVICKENISEVYAALLGCMSDYTTDSRGDVGAWVREAAMTSLMDLMLLLA---RTEPVLIEAHICERVMCCVAQQASEKIDRFRAHAARVFLTLLHFDSPPIPHVPHRQELESLFPRSDVATVNWNAPSQAFPLITQLLGLPTYRYHVLLGLAVSVGGLTESTVRHSTQSLFEYMKGIQKDAQVLQSFSETLLKVFEDNLLNDRVSVSLLKMLDQLLANGCFDIFTAEENHPFCVKLLTLCKEEIKKSKDIQKLRSSIAVLCGMVQFNGDVRKKILLQLFLLLGHPFPVIRKSTASQVYEMVLTYSDLVDAEVLDEVMSVLSDTAWDAELPVVREQRNRLCDLLGVPRPQLVPK 1191

[Close]

BLAST of Tubulin-specific chaperone D vs. UniProt/SwissProt
Match: sp|Q9BTW9|TBCD_HUMAN (Tubulin-specific chaperone D OS=Homo sapiens OX=9606 GN=TBCD PE=1 SV=2)

HSP 1 Score: 816.994 bits (2109), Expect = 0.000e+0
Identity = 470/1208 (38.91%), Postives = 698/1208 (57.78%), Query Frame = 2

Query:   50 KEDDEDLKY-IILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS-------ANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKW--EREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELI-----LAMESPNDIPETLKTE----IKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLW-------YKFLSECTTHKEKFVRTAAIEAFPEFMDCYCF----DRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGI----TNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYM-KDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETL-ISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            + +DE L +   L  F    E   L+  L+E+ G   + E+  +R + I ++YQ QPHLLDP+LE +++  + ++             F+ +Y++ K RGYKT +RL PHEV+D+EPVL +++     D+E W+ RY+LLLWLS+  +IPFD +  D          +  I  RIL+  + +L+  D ++ AAA ++S+F+ RPD +K   + E + W++  +     + + G   M G L+    +FK GKRED LP++  +L     +D  +     + LL +L  KLVQR+GL FLK KV  WRYQRG R L  NL   +     + P                 +++ED +V E +  V++ L+  LK+  T VRWSAAKG+GR+  RLP++LADD+V ++L  FS  E   +WHG CLALAELGRRG LLP RL +V+ +I+KAL YDEK G CS G NVRDAACYVCWAFARAY P+ELKP+V  I+S L++  +FDR +N RRAA+AAFQENVGRQG FPHGI+ILTT DYFAV N +NCFL +S+FIA F EY +PMIDHLV +K+ HWD  IREL A+AL+ L   APE+   +V P L++     DL+ R GSI+A  E+      LA +    + + L  +    +K I   L  R  +RGL G+LMR+A+C LI   S +KM F+GD +ID W        + L   ++H  + ++ AA+ A       Y      + D  I+ E    Y+ +     + T   +  A     LG  P ++L+        L  +   +  +  TS  E V    + E+R   L ++  IC+TVG+     +E +    + +IY  LL  +DDYT DS GD+G  VR++AM SL   + LL+ S   + E+ +    + I+  ++QQA EKIDR R  A  +F  L++     IP +P    ++ +F +     + W+AP   FP  ++LL    YRY ++LGLVVS+GG+TE T++HS ++L   +K  + D +     S  +L++F++    +RV  PL K +D +     +  F   +     + ++   K EI  +KDIQK+ SGI VFC M+QF   + R+A+  L +L+ H+FP+IRK TA+ +Y++LL Y ++V  D   E++ +L +T WD ELA VRE RN++C+L  +P P+L+ +
Sbjct:   15 EAEDETLAFGAALEAFGESAETRALLGRLREVHGGGAEREVALERFRVIMDKYQEQPHLLDPHLEWMMNLLLDIVQDQTSPASLVHLAFKFLYIITKVRGYKTFLRLFPHEVADVEPVLDLVTIQNPKDHEAWETRYMLLLWLSVTCLIPFDFSRLDGNLLTQPGQARMSIMDRILQIAESYLIVSDKARDAAAVLVSRFITRPD-VKQSKMAEFLDWSLCNLARSSFQTMQGVITMDGTLQALAQIFKHGKREDCLPYAATVLRC---LDGCRLPESNQTLLRKLGVKLVQRLGLTFLKPKVAAWRYQRGCRSLAANLQLLTQGQSEQKPLILT------------EDDDEDDDVPEGVERVIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRALADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEPQELKPFVTAISSALVIAAVFDRDINCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQVFPRLLSMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQLYDRQLYRGLGGQLMRQAVCVLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLA-----LGALPGFLLKGR------LQQVLTGLRAVTHTSP-EDV---SFAESRRDGLKAIARICQTVGVKAGAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMTSLMDLTLLLARS---QPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCEMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYSDVVGADVLDEVVTVLSDTAWDAELAVVREQRNRLCDLLGVPRPQLVPQ 1188

[Close]

BLAST of Tubulin-specific chaperone D vs. UniProt/SwissProt
Match: sp|Q5ZI87|TBCD_CHICK (Tubulin-specific chaperone D OS=Gallus gallus OX=9031 GN=TBCD PE=2 SV=1)

HSP 1 Score: 729.169 bits (1881), Expect = 0.000e+0
Identity = 412/1022 (40.31%), Postives = 607/1022 (59.39%), Query Frame = 2

Query:   47 AKEDDEDLKYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDSA-------NKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWER--EILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELI-----LAMESPNDIP--------ETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLW-------YKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDR----DLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITN-----EHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYM-KDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKT 2995
            ++E D   +  IL  F    EV  L+  L+ + G    +E+  ++   I ++YQ QPHLLD +LE +++  + +I  +          F+ +Y++ K RGYK  +RL PHEV+DL+PVL M+ D    D E W+ RY+LLLWLS++ +IPFD+  FD          + P   RIL+  K +L+  D ++ AAA ++SKF+ RPD ++ K + + + W +  +     + ++G   M G+L+    LFK GKRED LP++  +LE    +DN K     +++L +L  KLVQR+GL F+K KV  WRYQRG R L  NL + S           V     +  A +++E++E++++   +  V++ L+  LK+  T VRWSAAKG+GRI  RLPK LADD+V ++L  FS  E  ++WHG CLALAELGRRG LLP R+ +V+P+I+KAL YDEK G CS G+N+RDAACY+ WAFARAY+P EL P++  I+S L++  +FDR VN RRAA+AAFQENVGRQG FPHGI+ILT  DYFAV N  NC+L +S++IA F EY +PMIDHLV +K+ HWD  IREL+ KAL+ L P APEY+   VLP L+    G DL+ R G+I+A  E+      LA E+   I         E LK   + +CS    R  +RGL GELMR A+C LI   S +KM F+GDPII+ W        + L   +    + V+ +A+ A     + Y  +     D  ++ E    YI +      ++T + I+      LG  P+++L+           +  ++E L + + I + R   + E+R  AL ++ +IC+TVG+       E++ K+ + +IYA LL  + DYT DS GD+G  VRE+AM SL + + LL    Q +AE+ + ++ ++I+  ++QQ+ EKID+ R  AG +F  L++     +P IP  E ++ IF + + E L W A    FP  ++LL   AY+Y ++LGL VS+GG+TE T
Sbjct:   16 SREADVISRGNILESFTESQEVRALLGNLRTVYGDPVAQEVIVEKFIVIMDKYQEQPHLLDRHLEWMMNMLLDIIRDSGSPPVLFHLAFKFLYIITKVRGYKLFLRLFPHEVTDLQPVLDMIVDQNPKDCETWETRYMLLLWLSMICLIPFDLARFDGNILSEEGHTRMPTMDRILEIAKCYLVVSDKARDAAAVLVSKFIVRPD-VRQKRMADFLDWTLSMLSKSSFQSMEGTVVMNGMLQALAQLFKHGKREDCLPYAATVLEC---LDNCKLSESNQMVLRKLGMKLVQRLGLTFVKPKVAKWRYQRGCRSLAANLQAQS----------SVMQSQKITVAANEAEDDEEYDIPGEIENVVEQLLVGLKDKDTIVRWSAAKGIGRITGRLPKELADDVVGSLLDCFSFQETDNAWHGGCLALAELGRRGLLLPSRISDVVPVILKALTYDEKRGSCSVGSNLRDAACYLSWAFARAYDPSELIPFINQISSALVIAAVFDRDVNCRRAASAAFQENVGRQGTFPHGIDILTAADYFAVGNRVNCYLTISVYIAGFPEYTQPMIDHLVNMKINHWDSVIRELSTKALHNLTPRAPEYMANVVLPRLLPLSVGTDLHTRHGAILACAEITHALCKLAEENNRSITYYFNGKSLEGLKQIHQELCS----RQLYRGLGGELMRPAVCTLIEKLSLSKMPFKGDPIIEGWQWLINDSLRSLPLASCAARQHVKESAVSALSALCNEYYINENGEADPALQGELVTQYISEL-----QSTEQMIRCGFSLALGALPRFLLK---------GRLQQVLEGLRKVTLI-TPRDVSFAESRRDALIAIAEICQTVGVKGEGSQEEYICKDNVAQIYATLLNCVTDYTTDSRGDVGGWVREAAMTSLMKVTLLLV---QNEAELINANICKQIMCWLAQQSAEKIDKFRAHAGSVFLTLLHFDSPPVPHIPHREELERIFPRSEAETLNWNAASEAFPRITQLLALPAYQYYVLLGLSVSVGGLTETT 1001

[Close]

BLAST of Tubulin-specific chaperone D vs. UniProt/SwissProt
Match: sp|Q8L5R3|TBCD_ARATH (Tubulin-folding cofactor D OS=Arabidopsis thaliana OX=3702 GN=TFCD PE=2 SV=1)

HSP 1 Score: 568.54 bits (1464), Expect = 3.151e-180
Identity = 374/1178 (31.75%), Postives = 625/1178 (53.06%), Query Frame = 2

Query:  179 RLQYIFNQYQAQPHLLDPYLEXXXXXXX-XXXXXXXXXERKESFVFRLI-------YLMVKTRGYKTIIRLMPHEVSDLEPVLSML---------SDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDSA----------NKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKRE---DLLPF---STLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILAMESPNDI-PETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETV------GITNEHLTKNIILR--IYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAE---------IFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKDV-IPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEG-----DMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETL---ISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMYEI-VEEDQYSEIMNILQETIWDNELAEVREVRNKMCNL 3529
            +++ I ++YQ Q  L++PYLE ++   +  + +K   +E K   +  +I       Y +V   GYK +I+  PH+VSDLE  + +L         S +        +A+ V LLWLSI++++PFD++  D++          +  P+  +IL   K +L S    +  +  +LSK L RPD    K       W  +E+ + K + +  H  + G++   + +FK   R+   D+LP       +L  +N        R+ L+     KL QRIGLV L  +  +WRY      L  N+ ++S  S    P   V  +   E+ +DQ   +ED +V E+L E+++ L++ L++  T VRWSAAKG+GR+ SRL   L+D+++ ++L LFS  EG  SWHG CLALAEL RRG LLP+  P V+P+I+KAL+YD + G  S G++VRDAA YVCWAF RAY+ +++K  +  +A  L++V  FDR+VN RRAAAAAFQENVGRQG +PHGI+I++  DYF++ +  N +L +++ IA ++ Y+ P +D L+  K+ HWD ++REL A+AL  L+ + P++    VL  LI      DL  R G+ +A GE++LA+     +     +  +  I  +++K   +RG  GE+MR A+   I C S + +    +    +    L+E   H    ++ AA+ A  + +  Y    D     +   + I    + + +  +   + + LA LG  P Y L T    DI L + +          KIE     +  EAR  A+  L  +CET+         N+ L+  ++++  +   LL +LDDY++D+ GD+G+ VRE+A+  L + + +L    +  +E         +FD +L   ++  + +Q VEK+D++R TA K+   ++Y K V +P +P  E ++ I        L WA P F+FP F +LL+   Y   ++ GLV+SIGG+ +   + S  AL   ++E E           + L D IL +   + + DRV+ P  + I+ +    +   F+ +++ T      ++D   +E+  +KD  K+K+G+ +   +      I  KA + L+  +GH++P+IRK  A  +Y +LL   I V E++  +++ I+ E+ W+ ++   +  R ++C L
Sbjct:   68 KIRSIMDKYQEQGQLVEPYLESIVSPLMFIIRSKTVDLEAKPDEILEIIKPISIIIYALVTVCGYKAVIKFFPHQVSDLELAVLLLEKCHSTNSVSALRQESTGEMEAKCVTLLWLSILVLVPFDISSVDTSIADDKTFGVDDLAPLVLKILGFCKDYLCSAGPMRRISGLLLSKLLTRPDM--GKAFSSFFEW-TYEVLSCKEDSVTNHFRLLGVMEALSAIFKTASRKVLLDVLPIVLNDVTVLSKSNAAAKSSLLRKYLI-----KLTQRIGLVCLPHRSPSWRYVAQTASLSENMSTSS--SQRLAPDHTVTAILQPESLDDQ--EDEDMDVPEILEEIIEMLLSGLRDTDTVVRWSAAKGIGRVTSRLTSVLSDEVLSSVLELFSPGEGDGSWHGGCLALAELARRGLLLPRSFPLVVPVIVKALHYDVRRGPHSVGSHVRDAAAYVCWAFGRAYSHKDMKNVLDQLAPDLLIVGSFDREVNCRRAAAAAFQENVGRQGNYPHGIDIVSIADYFSLSSRVNSYLQVAVSIAQYEGYLYPFVDELLYNKICHWDKSLRELAAEALAPLVKYEPKHFANYVLEKLIPCTLSTDLCMRHGATLAAGEVVLALHQCGYVLSADSQKRMAGIVPSIEKARLYRGKGGEIMRLAVSRFIECISLSHVTL-AERTERILLDTLTENLRHPNSQIQNAAVSAVKQLVQSYLVGND-----KKSVDLILKHLKHLTDPNVAVRRGSALA-LGVLP-YELLTAKWKDIVLKLCS--------ACKIEVNPEDRDAEARVNAVKGLTSVCETLTQKRASDPGNDDLSLFLLIKTEVMDTLLKALDDYSVDNRGDVGSWVREAAVHGLEKCTYILCKKMETYSEGDYNDDTSSLFDSNLATRLIGGMLKQGVEKMDKLRETAAKVLQRILYHKSVSVPHVPYREKLEEILPNKA--NLQWAVPAFSFPRFVQLLKLRCYSKEVMSGLVISIGGLQDSLRKASLVALLEYMREGEAKDPKEQQSRESALGDDILWILQEYKKCDRVMVPCLQTIEILFSSKI---FLNQESYTFSFYAGVMDSLAIELRASKDFTKLKAGLAILGYIASVSHFISTKAFSQLLSFLGHRYPMIRKAAAEQVYLALLQNGILVTEEKMEKVIEIISESCWEADMETTKTQRLELCEL 1212

[Close]

BLAST of Tubulin-specific chaperone D vs. TrEMBL
Match: A0A504YBX5 (Tubulin-specific chaperone D OS=Fasciola gigantica OX=46835 GN=FGIG_01191 PE=4 SV=1)

HSP 1 Score: 997.653 bits (2578), Expect = 0.000e+0
Identity = 518/1189 (43.57%), Postives = 747/1189 (62.83%), Query Frame = 2

Query:   62 EDLKYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDSANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLG------SNSIESDNRNPFSFVPNVD-TVENANDQSENEE---DFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILAMESPNDIPETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPII--------------DLWYKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMYEIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLI 3556
            E+ +++I  +F H +EV +LI T+ E   LQ  EE  E+    IF  YQ QPHLLDPYL  ++   ++++   K   R   F FR++YLMVKTRGYK+IIRLMPH V D+EP L ML++    D   W+ RYVLLLWLSI+IM+PF +N  DS ++ PI  RIL   K +L     +Q AA+F+L++ + RPD ++  L    + W + +I+N       G   +CG+LR    + K G+R++L   +  +LE+  Q+ ++   +   + R  TKL+QRIGL+F   +  +W+YQRG R L  NL        N+ + +     +F  ++  T+ +   +S +E+   D E ++ + EV+D LINSL+N +T VRWSAAKGLGR+C RL +S+ +D++ AIL+L +RLE F++WHGACLALAELGRR  LLP +LPEV+P+I++AL+YDE+SG+ SYG+NVRDAACYVCWAFARAY   +L PYV  +A +L++V+LFDR+VNVRRAAAAAFQENVGRQGQFPHGIEILT CDYFAVRN  NC+L LS F+A F EY + MIDHL    +GHWD  IR L+A+ALN L  F+PEY++  +LP+ +  CT   LY+RQG++  T ELI  +      PE L          L +R QFRGLSGEL+RKA CHLI   S+  +   GDP+I              + W   L +C  HKE  ++ AA+ A+ + +  Y +D+D  ++  ++D      ++Q+ E   E  Q+  L +L   P         +D+    +   +EL+    +I S +T  WG+AR+ AL S++ I  T+G  +  LT  +I  +  +LL SL DYTLDS GDIG+ VRE+ M  L  +   L  SD   +   D  L +EI+  I QQ+VEKIDR R  AG+ F  ++Y +  I +IP  + VK IF+KD+C+ + W+A   TFP F +LL    YR+R+VLGLVVS+GG+TEKTV  S EAL   L  HE D ++  +    + ++   FA  +RVI PLF+ +DF+  DPV +  +  ++  LI++ID T  E   + D+ +IK+ I VF  MLQF+    +++ + +M+L+ HK+PVIRK  AT LY+ L+M+++VE +   ++  +L ETIW++EL E+R +RN +C +  +P+P++I
Sbjct:   10 EEEQFLIFNNFKHYDEVIKLISTITEATKLQTTEEHLEEEFIKIFGFYQEQPHLLDPYLPKMISDTLEVVKTTKTGSRAFHFAFRVLYLMVKTRGYKSIIRLMPHTVDDIEPTLVMLTEQDTEDANTWETRYVLLLWLSILIMVPFGLNCLDSEDRAPIVNRILDQSKRYLSLDGRTQEAASFLLARLVTRPDVVQAHL-TPVLDWCLEQIRNADCTTGKGQKLLCGVLRSLANICKVGRRQELFAHAPRLLESILQM-SIAAAKGNWIYRFETKLLQRIGLLFCPPRSFSWQYQRGLRSLADNLAPRLRELQNTTDGNTNQASNFSTSLQRTLTHGLTESTDEDEEFDLEHADEVAEVIDRLINSLRNQYTVVRWSAAKGLGRMCGRLSRSMVNDVLSAILLLCTRLEPFTAWHGACLALAELGRRSLLLPSKLPEVMPVILRALFYDERSGDHSYGSNVRDAACYVCWAFARAYQAVDLAPYVTQVAQSLVLVSLFDREVNVRRAAAAAFQENVGRQGQFPHGIEILTACDYFAVRNLKNCYLELSAFVAQFPEYTQAMIDHLATKLLGHWDVVIRFLSARALNVLCRFSPEYMLHSILPATVRCCTEAALYERQGNLFGTAELIEGLGKDAIGPELLXXXXXXX-XXLSERNQFRGLSGELLRKASCHLIEKSSRTHLPLHGDPVIVIMNLMLMRTSAFAETWRLLLDDCVAHKEVEIQKAAVSAYTQLLAAYLYDKDKHLQIAYRDKMFGHFTQQL-EANSETKQSGFLQVLADAP---------ADLFTGHVQKTLELVTAACRI-STKTRSWGDARASALKSVLGIMRTLGHGHPELTPEVIFSLGPILLQSLSDYTLDSRGDIGSRVRETGMNCLLGYLGFL-FSDPSTSNP-DPMLVEEIVVSIVQQSVEKIDRTRAAAGRAFSGILYHEPPIRYIPHVKKVKEIFSKDECDTIVWSAAHQTFPKFVQLLDLPEYRFRLVLGLVVSVGGLTEKTVLCSTEALTAYLLTHEADQKFITEFISTVNQISARFASDERVIVPLFRFVDFLLNDPVIAGAVNGESPILINLIDNTWNETKRSADVHRIKAAINVFGGMLQFEGSARKRSASLMMILMAHKYPVIRKSAATKLYECLVMFDLVEPEVMDQVTTLLTETIWESELGEIRPIRNTICEMLGVPVPRII 1182

[Close]

BLAST of Tubulin-specific chaperone D vs. TrEMBL
Match: A0A4E0S047 (Tubulin-specific chaperone D OS=Fasciola hepatica OX=6192 GN=D915_002510 PE=4 SV=1)

HSP 1 Score: 996.882 bits (2576), Expect = 0.000e+0
Identity = 520/1189 (43.73%), Postives = 751/1189 (63.16%), Query Frame = 2

Query:   62 EDLKYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDSANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLG------SNSIESDNRNPFSFVPNVD-TVENANDQSENEEDFEV---SELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILAMESPNDIPETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPII--------------DLWYKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMYEIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLI 3556
            E+ +++I  +F H +EV +LI T+ +   LQ  EE  E+    IF  YQ QPHLLDPYL  ++   ++++   K   R   F FR++YLMVKTRGYK+IIRLMPH V D+EP L ML++    D   W+ RYVLLLWLSI+IM+PF +N  DS ++ PI  RIL   K +L     +Q AA+F+L++ + RPD ++  L    + W + +IKN       G   +CG+LR    + K G+R++LL  +  +LE+   + ++   +   + R  TKL+QRIGL+F   +  +W+YQRG R L  NL        N+ + +     +F  +++ TV +   +S +++D      ++ + EV+D LINSL+N +T VRWSAAKGLGR+C RL +S+ +D++ AIL+L +RLE F++WHGACLALAELGRR  LLP +LPEV+P+I++AL+YDE+SG+ SYG+NVRDAACYVCWAFARAY   +L PYV  +A +L++V+LFDR+VNVRRAAAAAFQENVGRQGQFPHGIEILT CDYFAVRN  NC+L LS F+A F EY + MIDHL    +GHWD  IR L+A+ALN L  F+PEY++  +LP+ +  CT   LY+RQG++  T ELI  +      PE L  +IK I  TL +R QFRGLSGEL+RKA CHLI   S+ ++   GDP+I              + W   L +C  HKE  ++  A+ A+ + +  Y +D+D  ++  ++D      ++Q+ E   E  Q+  L +L   P         +D+    +   +EL+    +I S +T  WG+AR+ AL S++ I  T+G  +  LT  +I  +  +LL SL DYTLDS GDIG+ VRE+ M  L  +   L  SD       D  L +EI+  I QQ+VEKIDR R  AG+ F  ++Y +  I +IP  + VK IF+KD+C+ + W+A   TFP F +LL    YR+R+VLGLVVS+GG+TEKTV  S EAL   L  HE D ++  +    + ++   FA  +RVI PLF+ +DF+  DPV +  +  ++  LI++ID T  E   + D+ +IK+ I VF  MLQF+    +++ + +M+L+ HK+PVIRK  AT LY+ L+M+++VE +   ++  +L ETIW++EL E+R +RN +C +  +P+P++I
Sbjct:   10 EEEQFLIFNNFKHYDEVIKLISTITDATKLQTTEEHLEEEFIKIFGFYQEQPHLLDPYLPKMISDTLEVVKTTKTGSRAFHFAFRVLYLMVKTRGYKSIIRLMPHTVDDIEPTLVMLTEQDTEDANTWETRYVLLLWLSILIMVPFGLNCLDSEDRAPIVNRILDQSKRYLSLDGRTQEAASFLLARLVTRPDVVQAHL-TPVLDWCLEQIKNADCTTGKGQKLLCGVLRSLANICKVGRRQELLAHAPRLLESILHM-SIAAAKGNWIYRFETKLLQRIGLLFCPPRSFSWQYQRGLRSLADNLAPRLRELQNTTDGNTNQASNFSTSLERTVTHGLTESTDDDDELDLEHADEVAEVIDRLINSLRNQYTVVRWSAAKGLGRMCGRLSRSMVNDVLSAILLLCTRLEPFTAWHGACLALAELGRRSLLLPSKLPEVMPVILRALFYDERSGDHSYGSNVRDAACYVCWAFARAYQAADLAPYVTQVAQSLVLVSLFDREVNVRRAAAAAFQENVGRQGQFPHGIEILTACDYFAVRNLKNCYLELSAFVAQFPEYTQAMIDHLATKLLGHWDVVIRFLSARALNVLCRFSPEYMLHSILPATVRCCTEAALYERQGNLFGTAELIEGLGKDAIGPELL-VQIKEIVPTLSERNQFRGLSGELLRKASCHLIEKSSRTRLPLHGDPVIVKINLMSMRTSAFAETWRLLLDDCVAHKEVEIQKTAVSAYTQLLAAYLYDKDKHLQIAYRDKMFGHLTQQL-EANSETKQSGFLQVLADAP---------ADLFTGHVQKTLELVTAACRI-STKTRSWGDARASALKSVLGIMRTLGHGHPELTPEVIFSLGPILLQSLSDYTLDSRGDIGSRVRETGMNCLLGYLGFL-FSDPSTNNP-DPMLVEEIVVSIVQQSVEKIDRTRAAAGQAFSGILYHEPPIRYIPHVKKVKEIFSKDECDTIVWSAAHQTFPKFVQLLDLPEYRFRLVLGLVVSVGGLTEKTVLCSTEALTAYLLTHEADHKFITEFISTVNQISARFASDERVIVPLFRFVDFLLNDPVIAGAVNGESPILINLIDNTWNETKRSADVHRIKAAINVFGGMLQFEGSARKRSASLMMILMAHKYPVIRKSAATKLYECLVMFDLVEPEVMDQVTTLLTETIWESELDEIRPIRNTICEMLGVPVPRII 1182

[Close]

BLAST of Tubulin-specific chaperone D vs. TrEMBL
Match: A0A419QG24 (Tubulin-specific chaperone D OS=Clonorchis sinensis OX=79923 GN=Tbcd PE=4 SV=1)

HSP 1 Score: 993.416 bits (2567), Expect = 0.000e+0
Identity = 521/1169 (44.57%), Postives = 740/1169 (63.30%), Query Frame = 2

Query:   71 KYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDSANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIE----------SDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILAMESPNDIPETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMYEIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIP 3547
            K ++  +F H +EV   I  + ++    + EE+ E  L+ IF+ YQ QPHLLDPYLE L+ +CI +I  +    +   F FRL+YLMVKTRGYK++IRLMPH V D+EP +S+L    I D E W+ RYVLLLWLSI+ MIPF +   DS N+ PI +R+LK  K +L   + +Q AA+F+L++ + RPD I+  L +  + W + ++       + G    CG+LR+   + K G R++LLP +  IL+    + +   ++  L+ RL  KLVQR+GL+F   +   W+YQRG R L  NL    ++          SDN  P +    +D       + E  E   V E+  EV+D LI+ L+N +T VRWSAAKGLGR+C+RL  S+  D++ A+L L +RLE F++WHGACLALAELGRR  LLP +LPEV+P++++AL+YDE+SG+ +YG+NVRDAACYVCWAFARAY  ++  PYV  +AS LI+V+LFDR+VNVRRAAAAAFQENVGRQGQFPHGI+I+TTCDYFA+RN TNCFL LS+F+A F +Y +PMIDH+ +  + HWD +IR L A+ LN L PF  EY+++ +LP LI   T   LY +QG+I  T ELI A +    + E++   IK+I STL    Q RGLSGEL+RKA+CHLI  CS A   F  DP+I+ W  FL +C +HKE  +R AA  A+P  +  Y +  D T+RT+++DN       Q+   T E I + +L +LG++P  + E N         +   IELL   S+I + ++  WGEAR  +L +L+ IC  +G  +  L   ++  I  VLL +L DY++DS GDIG+LVRE  M+ L ++   L  S    AEI    L Q+ L  I QQAVEKIDR R  AG+ F  +++    IP IP  + +K +F +++C+   W + Q TF  F  LL    +R+R+VLGL VS+GG+TE TV  S EAL + L  HE D  +  +    +L+VF+ F  ++R+I P FK IDF+  DPV S    R++  L+ ++D    E  ++K++ +IKS I+V   MLQF+  +  +A   L+VL+GH++PVIRK  AT LY+ L++YE+V+ +   E++ +L ETIW++ L  +R +RNK+  L  +P P
Sbjct:  232 KCVVFDEFKHFDEVMAHIHAIHKVTEDVSSEELAEQDLKRIFDFYQEQPHLLDPYLERLISECISIIRSSTDRPKAFHFAFRLLYLMVKTRGYKSVIRLMPHSVDDIEPTISLLVSQDIGDPETWKTRYVLLLWLSILTMIPFSLECLDSPNEIPIVERVLKQSKIYLSRDERTQEAASFLLARLVTRPDVIQVHL-QPVVTWCIEQMHTADCSTVHGQAVTCGMLRVLANICKVGLRKELLPVANTILKAVISLPS-NVDKGNLIHRLEAKLVQRVGLLFCPPRSTGWQYQRGCRSLADNLAPRLLQETPDNIEVTTSDNAQPTTMTTKLD--PKPEQEEEEFELEYVDEV-AEVIDRLIHLLRNQYTVVRWSAAKGLGRMCNRLGSSMVSDVLAALLALCTRLEPFTAWHGACLALAELGRRSLLLPSKLPEVIPVVLRALFYDERSGDHNYGSNVRDAACYVCWAFARAYRAQDFSPYVNRVASALILVSLFDREVNVRRAAAAAFQENVGRQGQFPHGIDIITTCDYFALRNRTNCFLELSVFVAQFGDYTRPMIDHVTKELLSHWDGSIRFLAARTLNLLYPFEKEYMLQTILPELIAKSTDGPLYAKQGNIFGTAELIAAAKG-TPLDESILLGIKAIVSTLSSHNQLRGLSGELLRKAVCHLIQQCSLANTPFHEDPVIEDWRVFLDDCLSHKEVEIRAAAASAYPSLLSTYLYASDGTLRTDYRDNIYAHLVHQLNANT-ETILSGYLQVLGQSPASLFEGN---------VARTIELLATASRI-TPKSRNWGEARQNSLKALVGICMELGSQHPELNAVVLQSIGNVLLRALSDYSVDSRGDIGSLVREVGMKCLEQYLGFLVTSG--AAEIIQPSLVQDALCGIVQQAVEKIDRTRAVAGQAFAAILHHDPPIPHIPYSDQLKKLFPREECDSTMWRSAQQTFRKFVPLLDLPEFRFRLVLGLSVSVGGLTEDTVLCSSEALTSHLLLHESDKVFVEEFLCVVLQVFETFCHEERIIVPYFKFIDFLLNDPVISSITDRESPILVRLVDLIWEETKSSKEVLRIKSAIDVLGGMLQFEGTVRTRASKLLLVLLGHRYPVIRKSAATKLYECLMVYELVDPEATDEVVVLLTETIWESNLDTIRPIRNKVSELLGLPAP 1381

[Close]

BLAST of Tubulin-specific chaperone D vs. TrEMBL
Match: A0A4S2LQM0 (TFCD_C domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007117 PE=4 SV=1)

HSP 1 Score: 990.334 bits (2559), Expect = 0.000e+0
Identity = 526/1170 (44.96%), Postives = 740/1170 (63.25%), Query Frame = 2

Query:   71 KYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDSANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLG-------SNSIE---SDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILAMES-PNDIPETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMYEIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIP 3547
            K ++  +F H +EV   I  +  +    + EE+ E  L+ IF+ YQ QPHLLDPYLE L+ +CI +I  +    +   F FRL+YLMVKTRGYK++IRLMPH V D+EP +S+L    I D E W+ RYVLLLWLSI+ MIPF +   DS N+ PI +R+L   K +L   + +Q AA+F+L++ + RPD I+  L +  + W + ++       + G    CG+LR+   + K G R++LLP + +IL     I +   ++  L+ RL  KLVQR+GL+F   +   W+YQRG R L  NL        S +IE   SD+ +P +    +D       +    E   + E+  EV+D LI+ L+N +T VRWSAAKGLGR+C+RL  S+  D++ A+L L +RLE F++WHG+CLALAELGRR  LLP +LPEV+P++++AL+YDE+SG+ +YG+NVRDAACYVCWAFARAY  ++  PYV  +AS LI+V+LFDR+VNVRRAAAAAFQENVGRQGQFPHGI+I+TTCDYFA+RN TNCFL LS+F+A F EY +PMIDH+    + HWD +IR L A+ LN L PF  EY+++ +LP LI   T   LY +QG+I  T ELI A +  P D   ++   IK I STL    Q RGLSGEL+RKA+CHLI  CS A   F  DPIID W  FL +C +HKE  +R AA  A+P  +  Y +  D T+RT+++DN       Q+   T E I A +L +LG++P  + + N         ++  IELL   S+I + ++  WGEAR  +L +L+DIC  +G  +  L   ++  I  VLL +L DYT+DS GDIG+LVRE  M+ L ++   L  S   K  I   +L Q+ L  I QQAVEKIDR R  AG+ F  +++    IP IP  + +K +F +++C+   W + Q TF  F  LL    +R+R++LGL VS+GG+TE TV  S EAL + L  HE D  +  +    +L+VF+ F  ++R+I P FK IDF+  DPV S     ++  L+ +ID    E  ++K++ +IK+ I+V   MLQF+  +  +A   L+VL+GH++PVIRK TAT LY+ L++YE+V+ +   E++ +L ETIW++ L  VR VRNK+  L  +P P
Sbjct:   13 KCVVFDEFKHFDEVMAHIHAIHTVTEDVSTEELAEQDLKRIFDFYQEQPHLLDPYLERLISECISIIRSSTDRPKAFHFAFRLLYLMVKTRGYKSVIRLMPHSVDDIEPTISLLVSQDIGDPETWKTRYVLLLWLSILTMIPFSLECLDSPNEIPIVERVLTQSKIYLSRDERTQEAASFLLARLVTRPDVIQVHL-QPVVTWCIEQMHTADCSTVHGQAVACGVLRVLANICKIGLRKELLPVANIILRAVISIPS-NVDKGNLIHRLEAKLVQRVGLLFCPPRSTGWQYQRGCRSLADNLAPRLLQETSENIEVTTSDSAHPTTMATKLD--PKPEQEEVEFELEYIDEV-AEVIDRLIHLLRNQYTVVRWSAAKGLGRMCNRLGSSMVSDVLAALLSLCTRLEPFTAWHGSCLALAELGRRSLLLPSKLPEVIPVVLRALFYDERSGDHNYGSNVRDAACYVCWAFARAYRAQDFSPYVNRVASALILVSLFDREVNVRRAAAAAFQENVGRQGQFPHGIDIITTCDYFALRNRTNCFLELSVFVAHFGEYTRPMIDHVTRELLTHWDGSIRFLAARTLNLLYPFEKEYMLQTILPELIAKSTDGSLYAKQGNIFGTAELIAAAKGIPLD--ASILLGIKGIVSTLSSHNQLRGLSGELLRKAVCHLIQQCSLANTPFHEDPIIDDWRVFLDDCLSHKEVEIRAAAASAYPYLLSTYLYASDGTLRTDYRDNIYAHLVHQLNANT-ETILAGYLQVLGQSPASLFDGN---------VSRTIELLATASRI-TPKSRNWGEARQNSLKALVDICMELGSQHPELNAVVLQSIGNVLLRALSDYTVDSRGDIGSLVREVGMKCLEQYLGFLVTSGATK--IIQPNLVQDALCGIVQQAVEKIDRTRAVAGQAFAAILHHDPPIPHIPHSDQLKQLFPREECDSTMWRSAQQTFRKFVPLLDLPEFRFRLILGLSVSVGGLTEDTVLCSSEALTSHLLLHESDKVFVEEFLCVVLQVFETFCHEERIIVPYFKFIDFLLNDPVISSITDSESPILVRLIDLIWEETKSSKEVLRIKAAIDVLGGMLQFEGTVRTRASKLLLVLLGHRYPVIRKSTATKLYECLMVYELVDPEATDEVVVLLTETIWESNLDTVRPVRNKVSELLGLPSP 1162

[Close]

BLAST of Tubulin-specific chaperone D vs. TrEMBL
Match: H2KQ95 (Tubulin-specific chaperone D OS=Clonorchis sinensis OX=79923 GN=CLF_103485 PE=4 SV=1)

HSP 1 Score: 989.564 bits (2557), Expect = 0.000e+0
Identity = 522/1173 (44.50%), Postives = 740/1173 (63.09%), Query Frame = 2

Query:   71 KYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDSANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIE----------SDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPE----VLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILAMESPNDIPETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMYEIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIP 3547
            K ++  +F H +EV   I  + ++    + EE+ E  L+ IF+ YQ QPHLLDPYLE L+ +CI +I  +    +   F FRL+YLMVKTRGYK++IRLMPH V D+EP +S+L    I D E W+ RYVLLLWLSI+ MIPF +   DS N+ PI +R+LK  K +L   + +Q AA+F+L++ + RPD I+  L +  + W + ++       + G    CG+LR+   + K G R++LLP +  IL+    + +   ++  L+ RL  KLVQR+GL+F   +   W+YQRG R L  NL    ++          SDN  P +    +D       + E  E   V E+  EV+D LI+ L+N +T VRWSAAKGLGR+C+RL  S+  D++ A+L L +RLE F++WHGACLALAELGRR  LLP +LPE    V+P++++AL+YDE+SG+ +YG+NVRDAACYVCWAFARAY  ++  PYV  +AS LI+V+LFDR+VNVRRAAAAAFQENVGRQGQFPHGI+I+TTCDYFA+RN TNCFL LS+F+A F +Y +PMIDH+ +  + HWD +IR L A+ LN L PF  EY+++ +LP LI   T   LY +QG+I  T ELI A +    + E++   IK+I STL    Q RGLSGEL+RKA+CHLI  CS A   F  DP+I+ W  FL +C +HKE  +R AA  A+P  +  Y +  D T+RT+++DN       Q+   T E I + +L +LG++P  + E N         +   IELL   S+I + ++  WGEAR  +L +L+ IC  +G  +  L   ++  I  VLL +L DYT+DS GDIG+LVRE  M+ L ++   L  S    AEI    L Q+ L  I QQAVEKIDR R  AG+ F  +++    IP IP  + +K +F +++C+   W + Q TF  F  LL    +R+R+VLGL VS+GG+TE TV  S EAL + L  HE D  +  +    +L+VF+ F  ++R+I P FK IDF+  DPV S    R++  L+ ++D    E  ++K++ +IKS I+V   MLQF+  +  +A   L+VL+GH++PVIRK  AT LY+ L++YE+V+ +   E++ +L ETIW++ L  +R +RNK+  L  +P P
Sbjct:   13 KCVVFDEFKHFDEVMAHIHAIHKVTEDVSSEELAEQDLKRIFDFYQEQPHLLDPYLERLISECISIIRSSTDRPKAFHFAFRLLYLMVKTRGYKSVIRLMPHSVDDIEPTISLLVSQDIGDPETWKTRYVLLLWLSILTMIPFSLECLDSPNEIPIVERVLKQSKIYLSRDERTQEAASFLLARLVTRPDVIQVHL-QPVVTWCIEQMHTADCSTVHGQAVTCGMLRVLANICKVGLRKELLPVANTILKAVISLPS-NVDKGNLIHRLEAKLVQRVGLLFCPPRSTGWQYQRGCRSLADNLAPRLLQETPDNIEVTTSDNAQPTTMTTKLD--PKPEQEEEEFELEYVDEV-AEVIDRLIHLLRNQYTVVRWSAAKGLGRMCNRLGSSMVSDVLAALLALCTRLEPFTAWHGACLALAELGRRSLLLPSKLPEASQLVIPVVLRALFYDERSGDHNYGSNVRDAACYVCWAFARAYRAQDFSPYVNRVASALILVSLFDREVNVRRAAAAAFQENVGRQGQFPHGIDIITTCDYFALRNRTNCFLELSVFVAQFGDYTRPMIDHVTKELLSHWDGSIRFLAARTLNLLYPFEKEYMLQTILPELIAKSTDGPLYAKQGNIFGTAELIAAAKG-TPLDESILLGIKAIVSTLSSHNQLRGLSGELLRKAVCHLIQQCSLANTPFHEDPVIEDWRVFLDDCLSHKEVEIRAAAASAYPSLLSTYLYASDGTLRTDYRDNIYAHLVHQLNANT-ETILSGYLQVLGQSPASLFEGN---------VARTIELLATASRI-TPKSRNWGEARQNSLKALVGICMELGSQHPELNAVVLQSIGNVLLRALSDYTVDSRGDIGSLVREVGMKCLEQYLGFLVTSG--AAEIIQPSLVQDALCGIVQQAVEKIDRTRAVAGQAFAAILHHDPPIPHIPYSDQLKKLFPREECDSTMWRSAQQTFRKFVPLLDLPEFRFRLVLGLSVSVGGLTEDTVLCSSEALTSHLLLHESDKVFVEEFLCVVLQVFETFCHEERIIVPYFKFIDFLLNDPVISSITDRESPILVRLVDLIWEETKSSKEVLRIKSAIDVLGGMLQFEGTVRTRASKLLLVLLGHRYPVIRKSAATKLYECLIVYELVDPEATDEVVVLLTETIWESNLDTIRPIRNKVSELLGLPAP 1166

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Cavefish
Match: tbcd (tubulin folding cofactor D [Source:ZFIN;Acc:ZDB-GENE-060823-1])

HSP 1 Score: 541.962 bits (1395), Expect = 9.782e-173
Identity = 286/624 (45.83%), Postives = 399/624 (63.94%), Query Frame = 2

Query:   80 ILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS-------ANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNS---IESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILAM 1921
            +L  F+   EV  L+ +L E+       E   ++   I ++YQ QPHLLDP+LE +L+  ++LI   K         F+ +Y++ K RGYK  ++L+PHEV+D++PVL +L     +D E W+ RY+LLLWLS+  +IPFD++  D         N+E I  RIL   K +L   D S+ AA+ ++SKF+ RPD +K K L + + W +  +    +   +G   + G L+    LFK GKRED L ++  +L+  +Q   +    +  L +L  K+VQR+GL FLK ++  WRYQRG+R L  NL  ++   +  D +      P++++V +       EED+++ E +  V++ L+  LK+    VRWSAAKG+GR+  RLPK LADD+V ++L  FS  E  ++WHG CLALAELGRRG LLP RL +V+P+I+KAL YDEK G CS G+NVRDAACYVCWAFARAY+P EL PYV  IAS L++  +FDR V  R+AA+AAFQENVGRQG FPHGI+ILT  DYF V N  NC+L +S++IA F+EY KPMIDHLV  K+ HWD  IREL  KAL+ L P AP+Y+   VLP L+   +GMDL+ R G+I+A  E+  A+
Sbjct:   24 LLAGFSESEEVKALLASLPELHENLVTRETAREKFVVIMDRYQEQPHLLDPHLEWMLNMLLELIRNEKSPPLLVHLAFKFLYIISKVRGYKIFMQLLPHEVADMQPVLDLLCRQDPSDPETWETRYMLLLWLSMTCLIPFDLSRLDGHQTSESGMNRETIMDRILAVAKSYLQVADKSRDAASVLVSKFVTRPD-VKQKRLGDFLDWTLTTVSQCNVLSTEGSVSLDGALQALAQLFKHGKREDFLQYAPTVLQCLDQ-KKIAEINQANLRKLGVKVVQRLGLTFLKPRLARWRYQRGSRSLAVNLAPSTSVGVVLDTK------PDLESVSS-------EEDYDIPEEVENVIEQLLVGLKDKEGIVRWSAAKGIGRVTGRLPKELADDVVGSVLDSFSFQETDNTWHGGCLALAELGRRGLLLPSRLSDVVPVILKALMYDEKRGACSLGSNVRDAACYVCWAFARAYDPSELSPYVNQIASALVIAAIFDRNVTCRKAASAAFQENVGRQGTFPHGIDILTAADYFTVGNLNNCYLTISVYIAGFEEYTKPMIDHLVTRKINHWDGVIRELATKALHNLTPQAPDYMTNTVLPQLLPMASGMDLHGRHGAILACAEITHAL 632

HSP 2 Score: 217.238 bits (552), Expect = 3.261e-57
Identity = 122/382 (31.94%), Postives = 200/382 (52.36%), Query Frame = 2

Query: 2441 WGEARSYALTSLIDICETVGITNEHLTKNIILRI-----YAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVY-MKDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETL-ISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            + EAR  A T+L  +C T G++ +     ++  I     Y  LL  ++DYT DS GD+G                                  Q ++  ++QQA EKIDR R  AG +F  L++  +  +P IP  E + SIF  D  E L W A    FP  ++LL+   Y+Y  +LGL VS+GG+TE TV  S  +L   LK  + D     ++ D +L++F +    DRV  PL  ++D +  +  +  F   +     + ++   K EI  + D +K++S I V+C ++QF   + +K ++ LM+L+GH+FP+IR  TAT +Y+ LL Y ++V+     ++M +L +T W+N+L+ VR  RN++C+   +P P + +K
Sbjct:  750 YTEARRDAATALAQVCVTAGVSAQGSADCVVCEINVNGVYEALLDCMNDYTTDSRGDVGGCC-------------------------------QRMMCCLAQQASEKIDRYRAHAGAVFLQLLHSTQPEVPHIPHREELLSIFPPDSAESLNWNAASQAFPHVTQLLRLPVYQYHTLLGLTVSVGGLTETTVHFSSRSLFEHLKSIQQDGAALTQIGDALLQIFRDNLHNDRVSIPLMSMLDQMLSNGCFELFTTEEDHPFCVELLSLCKEEIKKSMDTKKLRSCIAVYCGLIQFQGGVRKKVLSQLMILLGHRFPLIRTVTATQVYEMLLTYDDVVDAAVLDDVMTVLSDTDWENDLSTVRIHRNQICDWLGVPQPTIPSK 1100

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009296.1 (pep scaffold:Pmarinus_7.0:GL477593:12935:45362:-1 gene:ENSPMAG00000008403.1 transcript:ENSPMAT00000009296.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 274.633 bits (701), Expect = 9.198e-82
Identity = 168/437 (38.44%), Postives = 253/437 (57.89%), Query Frame = 2

Query:   80 ILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDSA--------NKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNL-GSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIK 1363
            +L  F+ + EV +L+  L          E   +R   I ++YQ QPHLLDP+LE +L   + ++      +       + +Y++ K R YK  IRL PHEV+D EPVL++L      D E WQ RY+LLLWLS++ +IPFD+  FD A         ++P+ +R+L   K +L+  D+ + AAA +++KF+ RPD +K K L   + W++  + +++M  ++      G+LR    +FK GKR+D LP ++++L+   +   ++      L +L  KLVQRIGL FLK K+  WRYQRG+R LL NL      +   ++P            AND  ++E+  ++ E +  +++ L+  LK+  T VRWSAAKG+GR+  RL K LADD+V +IL   S  E   +WHG CLALAELGRRG LLP RLP+ +  II+
Sbjct:   27 VLYAFSDVEEVRRLLAALPGAASQPGDNEKITERFFLIMSKYQEQPHLLDPHLEWMLDLMLPMVRSEDSPDLMH-ITCKFLYIISKVRTYKPFIRLFPHEVADFEPVLALLEAQDPVDRETWQTRYILLLWLSMLSLIPFDLTRFDGALPGGASGTERKPVMERVLDVAKTYLVVTDLPRNAAATLVAKFVTRPD-VKQKHLPHFMDWSLSALSSMEMGTLEQEARADGMLRSLAQMFKHGKRDDFLPHASVVLQCVVKCRLLE-ASNTNLRKLSIKLVQRIGLTFLKPKLAAWRYQRGSRSLLDNLQAPGQQQQQQQSPLIVSSQASAAPRANDDDDDED-DDIPEEMEGIIEHLLFGLKDKDTVVRWSAAKGIGRVTGRLQKDLADDVVASILECLSVGETNKAWHGGCLALAELGRRGLLLPSRLPDAIAEIIQ 459

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009390.1 (pep scaffold:Pmarinus_7.0:GL476782:128285:138794:1 gene:ENSPMAG00000008498.1 transcript:ENSPMAT00000009390.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 159.844 bits (403), Expect = 2.270e-43
Identity = 101/321 (31.46%), Postives = 171/321 (53.27%), Query Frame = 2

Query: 2609 VRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKD-VIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETL-ISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITK 3562
            VRE AM SL    E++ +   +  E+    + +E + ++ QQAVEKIDR R  A  +   L++  +  +P IP  + +   F +     + W      F    ++L    Y+ R++LGL +S+GG+TE T + S +AL   +K    D E  N L   +L++F +  R  RV  PL  ++D +  +  +       + T  + ++   + E+  +KD  K+++G+ VFC ++QF     + A+  LM+L+ H +P+IRK TA+ LY+++L+Y +IVE D   EIM++L +T WD  L  V E    +C+L  +  P L  K
Sbjct:    1 VREVAMVSL---KEVILLVVDKCPEMLSPSVCEEAMCRLLQQAVEKIDRTREQAVSVLMALLHRDERPVPHIPHRQQLLDAFPRADLSAVNWRMASELFSRVVQILSLPVYQPRLLLGLTISVGGLTESTTRSSAQALFAFMKSIRQDTEAMNALCRTLLQIFRSNLRNSRVSVPLMAMLDKMLANGCFEAIAEDPSHTFPMEVVALVQQEMRGSKDTFKLQTGLPVFCGLIQFPGAARKNALLNLMMLLCHSYPIIRKATASQLYETMLVYDDIVEPDAAEEIMSLLSDTNWDATLPVVTE----LCDLLGVTRPVLKAK 314

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Nematostella
Match: EDO35005 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMP4])

HSP 1 Score: 817.379 bits (2110), Expect = 0.000e+0
Identity = 461/1155 (39.91%), Postives = 692/1155 (59.91%), Query Frame = 2

Query:  191 IFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFD-------SANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEH--IDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILAM---ESPNDIPETLKTEIKSICST---------LDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGI-----TNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQT----ETLISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMYEIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITKA 3565
            I ++YQ QPHLLDPYLE L+ + + ++       +     F+ IY++ K RG K ++RL  HEVSD+EP+L+M++    N++E W+ RY+LLLWLSI  MIPFDM+  D       S  + P+  RI+   K ++   D S+ AAA ++SKF+ RPD  K+KL  E I W++ EI   + E   I G   + GL+     L K GKREDLLP++ ++L+       +K     +L +L  KLVQR+GL F+K ++ +WRYQRG+R L+ NL                PN+  +         EE+++V E + +V++ L+  LK+  T VRWSAAKG+GRI  RLPK LAD++V ++L LF+  E   +WHG CLALAELGRRG LLPQRLPEV+P+++KAL YDE+ G  S G +VRDAACYVCW+FARAY+P+E++P+V+ ++S LI+ TLFDR+VN RRAA+AAFQENVGRQG FPHGIEILTT DY +V N ++ +LN+S++IA FKEY +PMI++LVE ++ HWD  +REL A+AL+ L    PEY+   +LP ++T  + MDL+ R GSI A  E++ A+      +  P TL   +K++            L     FRGL GE MR+A+ HLI   S ++  +QGD I DLW + L +   H E  ++  +  +     + Y  D      T+ ++  I  C  +++   L++ +  +   LG  PK++L         +  +  ++E L+  S++ +     + E+R+ AL SL  +  TVGI      N+ +T+  +  IY     ++ DYT DS GD+GA VRE++M  L + ++L+    Q  + + + D+ Q ++  + QQA EKIDR R  AG++   LV+    IP IP HE +  +F ++ C +L W+AP   FP+ ++LL    YRY  +LGL VS+GG+TE  V+ S  AL + L++     +  N  +D I+ +F    + DRVI PLFK++DF+     +  FI  +     +TL+++   TK EI    D +KI + I VFC +LQF  V   K++  L++L+ HKFP +RK TA  LY +++ Y+   E + ++  ++      D +L +VRE RNK+C++ D+P P L  K+
Sbjct:    2 ILDEYQEQPHLLDPYLEDLVGRLLSIVRDESNPPKMVHQAFKYIYVITKVRGPKCVVRLFTHEVSDIEPLLAMINKQNQNEHETWETRYILLLWLSIACMIPFDMSRLDGTFGAGTSEQRRPVVDRIIDVAKSYMCVPDKSRDAAALLISKFITRPDVKKHKL-AEFIDWSLKEITKSRNEANTIQGMMSLTGLMTSLALLLKHGKREDLLPYAPVVLKQIGSC-GIKDINNTVLRKLNVKLVQRLGLTFMKPRLASWRYQRGSRSLVSNLQG--------------PNIKVLHILF--LSQEEEYDVPEEIEDVVEQLLIGLKDKDTVVRWSAAKGIGRITGRLPKELADEVVGSLLELFTFSESDGAWHGGCLALAELGRRGLLLPQRLPEVVPVVLKALAYDERRGSYSVGNHVRDAACYVCWSFARAYDPKEIRPHVLALSSALIVTTLFDREVNCRRAASAAFQENVGRQGTFPHGIEILTTADYHSVGNRSHTYLNISVYIAQFKEYTRPMIENLVETRLQHWDGALRELAARALHNLTSSDPEYMATTMLPKVLTMTSSMDLFTRHGSIFACAEIVSALYHYGKQSTEPVTLDN-VKTLNLVTIIVISFFQLHAGQLFRGLGGEFMRQAISHLIEKLSLSQFPWQGDSITDLWQRILYDNLCHTEPPIQVKSCASTGAKCNQYYRDSTGKAITDIQEKLINHCVAELK-NQLQFPRVGYAQALGSLPKFML---------MGKLQKVVEGLIIASQVGN-DPGIYAESRNEALKSLASVACTVGIDRTACENDAVTEASLDAIYKAFFEAMQDYTTDSRGDVGAWVREASMTGLAQVTKLVL---QMDSSLLNPDVCQRLMCCLVQQASEKIDRTRAHAGEILVQLVHHDPRIPHIPHHEQLLELFKRETCSELNWSAPADCFPVVTRLLGMPTYRYPTLLGLTVSVGGLTESLVRQSTAALLSYLRDITSKKDDLNIFADTIINIFREHKKNDRVIVPLFKMLDFLLSSSCFEMFIPDENHGFPQTLVTL---TKEEIARIGDARKIITSINVFCQLLQFPGVTRSKSMQQLLMLLCHKFPRVRKTTADQLYTTIITYDDRCERRRND--HVFLFFYRDMDLPKVREERNKICDMLDMPRPVLKVKS 1118

[Close]

BLAST of Tubulin-specific chaperone D vs. Ensembl Medaka
Match: tbcd (tubulin folding cofactor D [Source:NCBI gene;Acc:101168869])

HSP 1 Score: 803.127 bits (2073), Expect = 0.000e+0
Identity = 463/1207 (38.36%), Postives = 695/1207 (57.58%), Query Frame = 2

Query:   47 AKEDDEDL--KYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDS------ANKEP-IAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELI-----LAMESPNDI-----PETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLW-------YKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIIL-----RIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKD-VIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETL-ISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMY-EIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITKA 3565
              E D D+  K  +L  F+  NE   ++ +L E+ G Q   E    R   I N YQ QPHLLDP+LE +++  ++ + +           F+ +Y++ K R YK  ++++PHEVSD+EPVL ++S     D E W+ RY+LLLWLS+  +IPFD++  D         KE  +  RIL   K +L+  D  + AA+ ++SKF+ RPD +K K L E + W++  I   +   +     + G L+    LFK GKR+DLL ++  +L+   Q   +    E +L +L  KL+QR+GL FLK ++  WRYQRG+R L+ NL S S++S +             +   D  E EED+++ E L  V++ L+  LK+  T VRWSAAKG+GR+  RLPK LAD++V ++L  FS  E  S+WHG CLALAELGRRG LLP RL +V+PLI+K+L YDEK G CS G+NVRDAACYVCW+FARAY P+EL+P+V  IASTL++ T+FDR +N RRAA+AAFQENVGRQG FPHGI+I+T  DYFAV N  NC+L +S+FIA F EY K MIDHL  +K+ HWD  IREL  KAL+ L P AP+Y+   VLP L+      DL+ R G+I+A GE+      +A+++   I     PE +  E+K+I   L +R Q+RG  G LMR A+C LI   S +K+  + DP++  W        + L   ++     +  A + A     + Y  D    + ++ +D  +   +  ++   +   +      LG  PK ++         LS I   +E +   ++ E   T    EAR  A+  +  +C   G+       +++       ++ VLL  L+DYT+ S GD+GA VRE+AM SL   S L++ S      +   +L + ++  ++QQA EKIDR R  A  +F  L++  +  IP IP  E +  IF  +    L W AP   F   ++LL    Y+YR +LGL VS+GG+TE TV  S ++L + LK  +GD E   +  D +LR+F +    DRV  PL K+++ +  +  +  F  ++     + ++D  K E   +KDI K+ + + VFC ++QF   + ++ ++ L++L+ H FPVIRK TA  +Y+ LL Y +I++ +   ++M  L +T W+++LA VR  RN++C+  ++P P+L+ KA
Sbjct:   14 GDEVDADIIAKTCLLGGFSEANETRSILSSLPEVHGDQRTTEHVTQRFLVIMNGYQEQPHLLDPHLEWMMNMMLEYVRREDCPPSLLHLSFKFLYIICKVRSYKIFMQILPHEVSDVEPVLQLISRQDPKDLETWETRYMLLLWLSMTCLIPFDLSRLDGHLTSTGGKKEDLVMNRILAIAKSYLVVTDSPRDAASVLISKFMTRPD-VKQKCLGEFLDWSLTMISQSRDTSVRDM-VLDGALQSLAKLFKHGKRDDLLQYAPTVLQCLEQ-KRLSESTEAMLRKLNVKLIQRLGLTFLKPRLAAWRYQRGSRSLVANL-SMSLQSSS----------GAAQTPQDSDEQEEDYDIPEELEAVIELLLIGLKDKETIVRWSAAKGIGRVTGRLPKELADEVVGSLLDCFSFQETDSAWHGGCLALAELGRRGLLLPSRLKDVVPLIVKSLTYDEKRGACSVGSNVRDAACYVCWSFARAYEPKELEPFVSQIASTLLITTVFDRNINCRRAASAAFQENVGRQGTFPHGIDIVTAADYFAVGNLNNCYLKISVFIAGFPEYTKCMIDHLTAMKINHWDCAIRELATKALHNLTPQAPDYMATTVLPQLLKMAGDTDLHSRHGAILACGEITHALYKVALQTNRSILNIISPECVD-ELKTIHFKLHERKQYRGFGGALMRPAICCLIEKLSLSKLPLKNDPVLTGWQWVIDDTLQTLHLISSGNADDIIAAVVSALSALCEGYYQDETGQVDSQMQDVLVSQYTEGLKSPQI-LTRCGSARALGCLPKVMIHNK------LSQILEGLEQMCTITQKEGSFT----EARRDAVRVIAQVCAKAGVCAHGRPDSVLCSENAAEVFGVLLSCLNDYTMSSRGDVGAWVREAAMTSLMELSILVASS---APNVLVPELVKPLMCCLAQQAAEKIDRYRAHAINVFLRLLHSTEPAIPHIPHREELLHIFPAETVASLNWKAPSQAFKYITQLLGLPEYQYRTLLGLSVSVGGITESTVHFSSQSLFDFLKGIQGDSETLGQFGDTLLRIFRDSLHNDRVSVPLLKMLNQLLNNSCFEIFTTQENHQFCVDLLDLCK-EFKKSKDISKLSACVSVFCGLIQFQGKVRKRVLSQLLLLLCHPFPVIRKTTANQMYEMLLTYDDIIDAEILEDVMTCLSDTNWESDLAIVRTHRNQLCDWLEVPRPQLVAKA 1190

[Close]

BLAST of Tubulin-specific chaperone D vs. Planmine SMEST
Match: SMESG000000964.1 (SMESG000000964.1)

HSP 1 Score: 2382.06 bits (6172), Expect = 0.000e+0
Identity = 1177/1179 (99.83%), Postives = 1179/1179 (100.00%), Query Frame = 2

Query:   29 MNHLDVAKEDDEDLKYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEXXXXXXXXXXXXXXXXERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDSANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVXXXXXXXFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILAMESPNDIPETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILRIYAVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMYEIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITKA 3565
            MNHLDVAKEDDEDLKYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEILLHKCIKLIAKAKKIERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDSANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVRRAAAAAFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILAMESPNDIPETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILRIY+VLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFS+LLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMYEIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITKA
Sbjct:    1 MNHLDVAKEDDEDLKYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWEDRLQYIFNQYQAQPHLLDPYLEILLHKCIKLIAKAKKIERKESFVFRLIYLMVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLSIVIMIPFDMNLFDSANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFLFRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFGKREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKVITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEEDFEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVEAILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYDEKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFDRQVNVRRAAAAAFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSIFIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIREVLPSLITSCTGMDLYKRQGSIMATGELILAMESPNDIPETLKTEIKSICSTLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSECTTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQETTLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESVRTSKWGEARSYALTSLIDICETVGITNEHLTKNIILRIYSVLLISLDDYTLDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKISQQAVEKIDRVRNTAGKLFYDLVYMKDVIPFIPDHEAVKSIFTKDQCEKLYWAAPQFTFPLFSQLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNSLKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSDFIGRQTETLISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKAINALMVLIGHKFPVIRKHTATYLYQSLLMYEIVEEDQYSEIMNILQETIWDNELAEVREVRNKMCNLFDIPIPKLITKA 1179

The following BLAST results are available for this feature:

BLAST of Tubulin-specific chaperone D vs. Ensembl Human
BLAST of Tubulin-specific chaperone D vs. Ensembl Celegans
BLAST of Tubulin-specific chaperone D vs. Ensembl Fly
BLAST of Tubulin-specific chaperone D vs. Ensembl Zebrafish
BLAST of Tubulin-specific chaperone D vs. Ensembl Xenopus
BLAST of Tubulin-specific chaperone D vs. Ensembl Mouse
BLAST of Tubulin-specific chaperone D vs. UniProt/SwissProt
BLAST of Tubulin-specific chaperone D vs. TrEMBL
BLAST of Tubulin-specific chaperone D vs. Ensembl Cavefish
BLAST of Tubulin-specific chaperone D vs. Ensembl Sea Lamprey
BLAST of Tubulin-specific chaperone D vs. Ensembl Yeast
BLAST of Tubulin-specific chaperone D vs. Ensembl Nematostella
BLAST of Tubulin-specific chaperone D vs. Ensembl Medaka
BLAST of Tubulin-specific chaperone D vs. Planmine SMEST

BLAST of Tubulin-specific chaperone D vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TBCD	0.000e+0	38.91	tubulin folding cofactor D [Source:HGNC Symbol;Acc...	[more]
TBCD	0.000e+0	37.72	tubulin folding cofactor D [Source:HGNC Symbol;Acc...	[more]
TBCD	8.958e-75	35.79	tubulin folding cofactor D [Source:HGNC Symbol;Acc...	[more]
TBCD	5.106e-68	32.64	tubulin folding cofactor D [Source:HGNC Symbol;Acc...	[more]
TBCD	7.584e-53	34.88	tubulin folding cofactor D [Source:HGNC Symbol;Acc...	[more]

BLAST of Tubulin-specific chaperone D vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
tbcd-1	2.599e-113	28.83	Tubulin-specific chaperone D [Source:UniProtKB/Sw...	[more]

BLAST of Tubulin-specific chaperone D vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
TBCD	0.000e+0	35.38	gene:FBgn0027509 transcript:FBtr0077829	[more]

BLAST of Tubulin-specific chaperone D vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
tbcd	0.000e+0	39.04	tubulin folding cofactor D [Source:ZFIN;Acc:ZDB-GE...	[more]

BLAST of Tubulin-specific chaperone D vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mis12	0.000e+0	38.24	MIS12 kinetochore complex component [Source:Xenbas...	[more]
mis12	0.000e+0	38.28	MIS12 kinetochore complex component [Source:Xenbas...	[more]
mis12	0.000e+0	39.08	MIS12 kinetochore complex component [Source:Xenbas...	[more]
mis12	0.000e+0	37.62	MIS12 kinetochore complex component [Source:Xenbas...	[more]
mis12	0.000e+0	37.32	MIS12 kinetochore complex component [Source:Xenbas...	[more]

BLAST of Tubulin-specific chaperone D vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Tbcd	0.000e+0	39.02	tubulin-specific chaperone d [Source:MGI Symbol;Ac...	[more]
Tbcd	1.245e-16	60.71	tubulin-specific chaperone d [Source:MGI Symbol;Ac...	[more]
Tbcd	4.250e-13	46.25	tubulin-specific chaperone d [Source:MGI Symbol;Ac...	[more]

BLAST of Tubulin-specific chaperone D vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q28205\|TBCD_BOVIN	0.000e+0	39.37	Tubulin-specific chaperone D OS=Bos taurus OX=9913...	[more]
sp\|Q8BYA0\|TBCD_MOUSE	0.000e+0	39.02	Tubulin-specific chaperone D OS=Mus musculus OX=10...	[more]
sp\|Q9BTW9\|TBCD_HUMAN	0.000e+0	38.91	Tubulin-specific chaperone D OS=Homo sapiens OX=96...	[more]
sp\|Q5ZI87\|TBCD_CHICK	0.000e+0	40.31	Tubulin-specific chaperone D OS=Gallus gallus OX=9...	[more]
sp\|Q8L5R3\|TBCD_ARATH	3.151e-180	31.75	Tubulin-folding cofactor D OS=Arabidopsis thaliana...	[more]

BLAST of Tubulin-specific chaperone D vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A504YBX5	0.000e+0	43.57	Tubulin-specific chaperone D OS=Fasciola gigantica...	[more]
A0A4E0S047	0.000e+0	43.73	Tubulin-specific chaperone D OS=Fasciola hepatica ...	[more]
A0A419QG24	0.000e+0	44.57	Tubulin-specific chaperone D OS=Clonorchis sinensi...	[more]
A0A4S2LQM0	0.000e+0	44.96	TFCD_C domain-containing protein OS=Opisthorchis f...	[more]
H2KQ95	0.000e+0	44.50	Tubulin-specific chaperone D OS=Clonorchis sinensi...	[more]

BLAST of Tubulin-specific chaperone D vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
tbcd	9.782e-173	45.83	tubulin folding cofactor D [Source:ZFIN;Acc:ZDB-GE...	[more]

BLAST of Tubulin-specific chaperone D vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000009296.1	9.198e-82	38.44	pep scaffold:Pmarinus_7.0:GL477593:12935:45362:-1 ...	[more]
ENSPMAT00000009390.1	2.270e-43	31.46	pep scaffold:Pmarinus_7.0:GL476782:128285:138794:1...	[more]

BLAST of Tubulin-specific chaperone D vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Tubulin-specific chaperone D vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO35005	0.000e+0	39.91	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Tubulin-specific chaperone D vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1


Match Name	E-value	Identity	Description
tbcd	0.000e+0	38.36	tubulin folding cofactor D [Source:NCBI gene;Acc:1...	[more]

BLAST of Tubulin-specific chaperone D vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000000964.1	0.000e+0	99.83	SMESG000000964.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30002829 ID=SMED30002829|Name=Tubulin-specific chaperone D|organism=Schmidtea mediterranea sexual|type=transcript|length=3748bp
TTAAATTGTGGCGATAATTAAAATAAAAATGAATCACTTAGATGTCGCTA
AGGAAGACGATGAAGATTTAAAATACATAATTTTAACAGATTTCGCTCAT
CTTAATGAAGTGAATCAATTAATTGATACATTACAGGAAATTATTGGTTT
ACAAAATAAAGAAGAAATATGGGAAGATCGACTTCAATATATATTTAACC
AGTATCAAGCTCAACCACACCTATTAGATCCATATTTAGAAATTTTGCTT
CATAAATGTATTAAATTAATTGCGAAAGCTAAAAAAATCGAAAGAAAGGA
AAGTTTTGTGTTTCGTCTAATTTATTTAATGGTCAAGACTAGAGGATATA
AGACGATTATAAGATTAATGCCTCATGAAGTTTCAGATTTAGAACCTGTT
TTATCAATGCTTTCAGATGTCACCATAAATGACAACGAAAACTGGCAAGC
TCGATATGTTCTCCTATTGTGGTTATCCATAGTAATAATGATACCCTTTG
ACATGAACCTGTTTGACAGTGCTAACAAAGAACCCATTGCTCAGCGAATT
TTAAAGACTGGAAAGTATTTTCTGATGTCAAAAGATGTTTCTCAAATTGC
AGCAGCATTTATGCTGTCAAAGTTTTTATTTCGACCTGATACAATCAAAA
ACAAATTGCTAGAAGAGACAATTCATTGGGCAGTTCATGAAATCAAGAAT
GTTAAAATGGAGCATATTGATGGCCATAATTTTATGTGTGGCTTATTGAG
GCTTTTCACCTACCTGTTCAAATTCGGGAAAAGAGAAGATCTGCTACCTT
TCAGCACTCTCATTCTCGAAACCAATAATCAAATCGATAATGTTAAATGG
GAAAGAGAAATTCTTTTATGCAGATTAAGAACTAAACTTGTTCAAAGAAT
AGGTTTAGTTTTTCTTAAAGTTAAAGTGATAACTTGGAGATACCAGAGAG
GAAATCGAGTACTTCTTCATAATTTGGGTAGTAATTCAATAGAATCTGAT
AACAGGAATCCCTTTTCATTTGTTCCTAATGTTGACACTGTTGAAAATGC
TAACGATCAATCAGAAAATGAGGAAGACTTTGAAGTATCGGAACTTTTAA
ATGAAGTCATGGATTTTTTAATTAATTCTTTAAAAAATTACTTTACATTC
GTTCGTTGGTCTGCAGCAAAAGGTCTTGGAAGAATATGTAGTCGCTTACC
CAAATCACTAGCAGACGATATTGTTGAAGCTATATTAGTATTATTTTCTC
GCTTGGAAGGATTCAGCTCTTGGCATGGGGCTTGCCTTGCTTTGGCTGAG
TTGGGTCGTCGCGGTTTCCTTCTTCCTCAACGGTTACCAGAAGTATTGCC
ATTGATTATCAAAGCTCTTTACTATGATGAAAAAAGTGGTGAATGTAGTT
ATGGAGCTAATGTGCGAGATGCAGCTTGCTACGTTTGTTGGGCCTTTGCA
AGAGCGTATAATCCAGAAGAGTTAAAACCTTATGTTGTTGACATTGCTAG
TACTCTGATTATGGTGACATTGTTCGATCGACAAGTGAATGTTAGAAGAG
CAGCTGCTGCTGCTTTTCAAGAAAATGTTGGCAGACAGGGTCAATTTCCT
CATGGAATCGAAATTCTCACGACATGTGATTATTTTGCTGTTCGTAATTC
AACGAATTGTTTTCTAAACCTAAGCATTTTTATTGCTTCCTTCAAAGAAT
ATGTAAAACCAATGATCGATCATCTCGTTGAATTAAAAGTTGGTCACTGG
GATTATAATATACGAGAACTTACTGCAAAGGCTTTAAATAAGTTGTTACC
TTTTGCACCAGAATATCTTATTAGAGAAGTGTTGCCCAGCCTTATAACCT
CGTGTACTGGTATGGATCTCTATAAACGGCAAGGATCAATTATGGCAACT
GGAGAGTTAATATTGGCAATGGAAAGTCCTAATGATATTCCAGAAACATT
GAAAACGGAAATTAAATCTATTTGCTCGACTTTGGACAAGCGAATGCAAT
TCAGGGGTCTTAGTGGAGAATTAATGCGAAAAGCAATGTGTCACTTAATA
TGGTGTTGCTCGAAAGCTAAGATGAGGTTTCAAGGCGATCCTATTATTGA
TTTGTGGTACAAGTTTTTAAGCGAATGTACAACACACAAGGAGAAATTTG
TTCGAACTGCTGCAATCGAGGCTTTTCCAGAATTTATGGATTGCTATTGT
TTCGATCGAGATTTAACTATTAGAACTGAGTTTAAAGATAATTATATTGA
GGATTGTTCACGTCAAATACAAGAGACTACACTCGAGTATATCCAAGCTA
CTCATTTAGCCATTCTCGGGAAAACTCCAAAATATATTCTAGAAACTAAT
CACAAGTCCGATATTGACTTATCCATGATAACCTATATAATTGAACTTCT
GTTACGAACTTCTAAGATAGAATCTGTTCGAACCTCGAAATGGGGCGAGG
CGAGAAGTTACGCTTTGACCAGTCTTATTGACATATGTGAAACAGTGGGC
ATCACAAATGAACATTTAACTAAAAACATTATCCTTAGAATATATGCTGT
ATTATTGATTAGTCTGGATGATTACACTCTGGATAGTCACGGTGATATCG
GGGCTTTAGTTCGAGAATCTGCTATGCGATCTTTGTATAGATTTAGTGAA
CTTTTATCGATATCTGATCAACGAAAAGCAGAAATATTTGATGAAGATCT
CACGCAGGAAATATTATCGAAAATCTCTCAACAAGCTGTTGAGAAAATCG
ATAGAGTTAGAAACACAGCTGGAAAATTATTTTATGATCTTGTCTATATG
AAAGATGTTATTCCTTTCATTCCGGATCATGAAGCTGTAAAATCAATATT
TACTAAGGATCAATGCGAGAAACTGTATTGGGCAGCACCTCAATTTACAT
TTCCTTTGTTCAGTAAACTTCTGCAATTCGATGCATATCGCTACCGAATA
GTTCTCGGTTTGGTAGTCAGCATCGGTGGAATGACTGAGAAAACCGTTCA
ACACAGTCGCGAAGCTCTTCATAATTCTCTTAAAGAACACGAAGGTGACA
TGGAATATTTTAATAAATTATCGGATTGTATTCTAAGAGTTTTTGATAAC
TTCGCTCGTCAGGATCGCGTTATTTATCCATTATTCAAATTGATCGATTT
TATTCACGGTGATCCAGTTTACAGTGATTTTATCGGCAGACAAACTGAAA
CTCTTATTTCCATTATTGATAAGACCAAATTGGAAATTTGTACCACCAAG
GATATTCAGAAAATCAAATCTGGAATTGAAGTCTTTTGTACGATGTTGCA
GTTCGATGAGGTGATTTGGCGGAAAGCAATAAATGCTTTAATGGTTCTCA
TTGGGCACAAGTTTCCTGTAATTCGAAAACATACTGCTACATATCTGTAT
CAGTCACTTTTGATGTATGAAATTGTGGAAGAGGACCAATATTCGGAAAT
AATGAATATTCTCCAGGAAACTATTTGGGACAATGAACTTGCCGAAGTAA
GAGAAGTTAGAAATAAAATGTGTAATTTATTTGATATTCCAATTCCGAAA
CTGATAACAAAAGCATAATTTTCACAAGAAATGGAATTTATTTAAATAAA
TAGTTTTCTTTTATTTGATATAAGTACTTATAAATTCTTTATTACCGTAA
AAATACTTTCCCCCAAATGATACTATTATTTTTGTTCTTTGATACATGCG
TTTTCTGTAATAAGTGTTAATGTTTCTGAAAATAAAGTTATGGCCGGC

protein sequence of SMED30002829-orf-1

>SMED30002829-orf-1 ID=SMED30002829-orf-1|Name=SMED30002829-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1180bp
MNHLDVAKEDDEDLKYIILTDFAHLNEVNQLIDTLQEIIGLQNKEEIWED
RLQYIFNQYQAQPHLLDPYLEILLHKCIKLIAKAKKIERKESFVFRLIYL
MVKTRGYKTIIRLMPHEVSDLEPVLSMLSDVTINDNENWQARYVLLLWLS
IVIMIPFDMNLFDSANKEPIAQRILKTGKYFLMSKDVSQIAAAFMLSKFL
FRPDTIKNKLLEETIHWAVHEIKNVKMEHIDGHNFMCGLLRLFTYLFKFG
KREDLLPFSTLILETNNQIDNVKWEREILLCRLRTKLVQRIGLVFLKVKV
ITWRYQRGNRVLLHNLGSNSIESDNRNPFSFVPNVDTVENANDQSENEED
FEVSELLNEVMDFLINSLKNYFTFVRWSAAKGLGRICSRLPKSLADDIVE
AILVLFSRLEGFSSWHGACLALAELGRRGFLLPQRLPEVLPLIIKALYYD
EKSGECSYGANVRDAACYVCWAFARAYNPEELKPYVVDIASTLIMVTLFD
RQVNVRRAAAAAFQENVGRQGQFPHGIEILTTCDYFAVRNSTNCFLNLSI
FIASFKEYVKPMIDHLVELKVGHWDYNIRELTAKALNKLLPFAPEYLIRE
VLPSLITSCTGMDLYKRQGSIMATGELILAMESPNDIPETLKTEIKSICS
TLDKRMQFRGLSGELMRKAMCHLIWCCSKAKMRFQGDPIIDLWYKFLSEC
TTHKEKFVRTAAIEAFPEFMDCYCFDRDLTIRTEFKDNYIEDCSRQIQET
TLEYIQATHLAILGKTPKYILETNHKSDIDLSMITYIIELLLRTSKIESV
RTSKWGEARSYALTSLIDICETVGITNEHLTKNIILRIYAVLLISLDDYT
LDSHGDIGALVRESAMRSLYRFSELLSISDQRKAEIFDEDLTQEILSKIS
QQAVEKIDRVRNTAGKLFYDLVYMKDVIPFIPDHEAVKSIFTKDQCEKLY
WAAPQFTFPLFSKLLQFDAYRYRIVLGLVVSIGGMTEKTVQHSREALHNS
LKEHEGDMEYFNKLSDCILRVFDNFARQDRVIYPLFKLIDFIHGDPVYSD
FIGRQTETLISIIDKTKLEICTTKDIQKIKSGIEVFCTMLQFDEVIWRKA
INALMVLIGHKFPVIRKHTATYLYQSLLMYEIVEEDQYSEIMNILQETIW
DNELAEVREVRNKMCNLFDIPIPKLITKA*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR033162	TBCD
IPR011989	ARM-like
IPR022577	Tubulin_specific_chaperoneD_C
IPR016024	ARM-type_fold
IPR011528	NERD

Vocabulary: **molecular function**
Term	Definition
GO:0005488	binding
GO:0005096	GTPase activator activity
GO:0048487	beta-tubulin binding

Vocabulary: **biological process**
Term	Definition
GO:0007021	tubulin complex assembly
GO:0007023	post-chaperonin tubulin folding pathway
GO:0043547	positive regulation of GTPase activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR011989	Armadillo-like helical	GENE3D	G3DSA:1.25.10.10		coord: 337..724 e-value: 1.2E-6 score: 29.5
IPR022577	Tubulin-specific chaperone D, C-terminal	PFAM	PF12612	TFCD_C	coord: 893..1078 e-value: 1.6E-48 score: 165.1
IPR033162	Tubulin-folding cofactor D	PANTHER	PTHR12658	BETA-TUBULIN COFACTOR D	coord: 57..1122
IPR016024	Armadillo-type fold	SUPERFAMILY	SSF48371	ARM repeat	coord: 351..1042

Main menu

Tubulin-specific chaperone D

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Owlery

blazegraph-runner