Interferon regulatory factor 2-binding protein 2

Overview
NameInterferon regulatory factor 2-binding protein 2
Smed IDSMED30002828
Length (bp)1954
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Interferon regulatory factor 2-binding protein 2 (SMED30002828) t-SNE clustered cells

Violin plots show distribution of expression levels for Interferon regulatory factor 2-binding protein 2 (SMED30002828) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Interferon regulatory factor 2-binding protein 2 (SMED30002828) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Interferon regulatory factor 2-binding protein 2 (SMED30002828) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30002828

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30002828h1SMcG0015655 SmedASXL_012176SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30002828h1SMcG0015655 dd_Smed_v4_18245_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30002828h1SMcG0015655 dd_Smed_v4_18245_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
parapharyngeal regionSMED30002828h1SMcG0015655 dd_Smed_v4_18245_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30002828h1SMcG0015655 dd_Smed_v4_18245_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30002828h1SMcG0015655 dd_Smed_v6_18245_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30002828h1SMcG0015655 OX_Smed_1.0.22437ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Human
Match: IRF2BPL (interferon regulatory factor 2 binding protein like [Source:HGNC Symbol;Acc:HGNC:14282])

HSP 1 Score: 94.3597 bits (233), Expect = 2.193e-19
Identity = 40/57 (70.18%), Postives = 48/57 (84.21%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            S++ ++ S+RQ CYLCDLPR PWAM+ DFSE VCRGCVNYEGADRIE VIE A+ +K
Sbjct:    2 SAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLK 58

HSP 2 Score: 91.6633 bits (226), Expect = 1.447e-18
Identity = 41/85 (48.24%), Postives = 52/85 (61.18%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  ++   +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  715 CTICHERLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 789
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Human
Match: IRF2BP1 (interferon regulatory factor 2 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:21728])

HSP 1 Score: 92.4337 bits (228), Expect = 5.529e-19
Identity = 41/85 (48.24%), Postives = 52/85 (61.18%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R +++                E+YCPS +KC L GSS PW+F+Q EI TIL+GD K
Sbjct:  503 CTLCRERLEDTHFVQCPSVPGHKFCFPCSREFIKAQGPAG----------EVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIK 577

HSP 2 Score: 87.0409 bits (214), Expect = 3.490e-17
Identity = 35/53 (66.04%), Postives = 44/53 (83.02%), Query Frame = 3 
Query:  429 MNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            +  S+RQ CYLCDLP+ PWAM+ DFSE VCRGCVN+EGADRIE +I+ A+ +K
Sbjct:    4 VQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLK 56
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Human
Match: IRF2BP2 (interferon regulatory factor 2 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:21729])

HSP 1 Score: 92.4337 bits (228), Expect = 6.710e-19
Identity = 37/50 (74.00%), Postives = 43/50 (86.00%), Query Frame = 3 
Query:  438 SQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADR+E VIE A+ +K
Sbjct:   11 SRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLK 60

HSP 2 Score: 92.0485 bits (227), Expect = 8.658e-19
Identity = 41/85 (48.24%), Postives = 53/85 (62.35%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  +++  +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  506 CTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 580
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Human
Match: IRF2BP2 (interferon regulatory factor 2 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:21729])

HSP 1 Score: 92.4337 bits (228), Expect = 6.739e-19
Identity = 37/50 (74.00%), Postives = 43/50 (86.00%), Query Frame = 3 
Query:  438 SQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADR+E VIE A+ +K
Sbjct:   11 SRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLK 60

HSP 2 Score: 92.0485 bits (227), Expect = 9.093e-19
Identity = 41/85 (48.24%), Postives = 53/85 (62.35%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  +++  +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  490 CTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 564
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Celegans
Match: tag-260 (pep chromosome:WBcel235:V:13370083:13372724:-1 gene:WBGene00010867.1 transcript:M04G12.1d.3 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-260)

HSP 1 Score: 83.9593 bits (206), Expect = 6.640e-18
Identity = 39/102 (38.24%), Postives = 57/102 (55.88%), Query Frame = 3 
Query: 1566 RCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNKEIKTSPKLFNVVAEVG 1871
            RC  C+ +LE THFVQCP    HKFCF C+R+ ++          +     ++YCPS +KC L GS+ PW+F+Q EI  IL  +  E K + +   +   +G
Sbjct:  112 RCTLCNERLEDTHFVQCPTVSIHKFCFPCSRSSIK----------DQCKSSDMYCPSGDKCPLVGSAMPWAFMQGEIAQILGDEYDEFKRTREAHGLAPPMG 203
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Celegans
Match: tag-260 (pep chromosome:WBcel235:V:13370083:13372897:-1 gene:WBGene00010867.1 transcript:M04G12.1d.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-260)

HSP 1 Score: 83.9593 bits (206), Expect = 6.640e-18
Identity = 39/102 (38.24%), Postives = 57/102 (55.88%), Query Frame = 3 
Query: 1566 RCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNKEIKTSPKLFNVVAEVG 1871
            RC  C+ +LE THFVQCP    HKFCF C+R+ ++          +     ++YCPS +KC L GS+ PW+F+Q EI  IL  +  E K + +   +   +G
Sbjct:  112 RCTLCNERLEDTHFVQCPTVSIHKFCFPCSRSSIK----------DQCKSSDMYCPSGDKCPLVGSAMPWAFMQGEIAQILGDEYDEFKRTREAHGLAPPMG 203
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Celegans
Match: tag-260 (pep chromosome:WBcel235:V:13370083:13372897:-1 gene:WBGene00010867.1 transcript:M04G12.1d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-260)

HSP 1 Score: 83.9593 bits (206), Expect = 6.640e-18
Identity = 39/102 (38.24%), Postives = 57/102 (55.88%), Query Frame = 3 
Query: 1566 RCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNKEIKTSPKLFNVVAEVG 1871
            RC  C+ +LE THFVQCP    HKFCF C+R+ ++          +     ++YCPS +KC L GS+ PW+F+Q EI  IL  +  E K + +   +   +G
Sbjct:  112 RCTLCNERLEDTHFVQCPTVSIHKFCFPCSRSSIK----------DQCKSSDMYCPSGDKCPLVGSAMPWAFMQGEIAQILGDEYDEFKRTREAHGLAPPMG 203
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Celegans
Match: tag-260 (pep chromosome:WBcel235:V:13370083:13380262:-1 gene:WBGene00010867.1 transcript:M04G12.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-260)

HSP 1 Score: 84.3445 bits (207), Expect = 4.328e-17
Identity = 39/102 (38.24%), Postives = 57/102 (55.88%), Query Frame = 3 
Query: 1566 RCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNKEIKTSPKLFNVVAEVG 1871
            RC  C+ +LE THFVQCP    HKFCF C+R+ ++          +     ++YCPS +KC L GS+ PW+F+Q EI  IL  +  E K + +   +   +G
Sbjct:  270 RCTLCNERLEDTHFVQCPTVSIHKFCFPCSRSSIK----------DQCKSSDMYCPSGDKCPLVGSAMPWAFMQGEIAQILGDEYDEFKRTREAHGLAPPMG 361

HSP 2 Score: 83.9593 bits (206), Expect = 4.737e-17
Identity = 32/48 (66.67%), Postives = 40/48 (83.33%), Query Frame = 3 
Query:  444 RQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            RQ CYLCDLPR+PWA++ D+ E VCRGCVNYEG+DRIE V+E+ +  K
Sbjct:   49 RQQCYLCDLPRWPWAIINDYIEPVCRGCVNYEGSDRIELVLEETRQQK 96
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Celegans
Match: tag-260 (pep chromosome:WBcel235:V:13370109:13373020:-1 gene:WBGene00010867.1 transcript:M04G12.1c.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-260)

HSP 1 Score: 84.3445 bits (207), Expect = 4.564e-17
Identity = 32/48 (66.67%), Postives = 40/48 (83.33%), Query Frame = 3 
Query:  444 RQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            RQ CYLCDLPR+PWA++ D+ E VCRGCVNYEG+DRIE V+E+ +  K
Sbjct:   39 RQQCYLCDLPRWPWAIINDYIEPVCRGCVNYEGSDRIELVLEETRQQK 86

HSP 2 Score: 84.3445 bits (207), Expect = 4.731e-17
Identity = 39/102 (38.24%), Postives = 57/102 (55.88%), Query Frame = 3 
Query: 1566 RCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNKEIKTSPKLFNVVAEVG 1871
            RC  C+ +LE THFVQCP    HKFCF C+R+ ++          +     ++YCPS +KC L GS+ PW+F+Q EI  IL  +  E K + +   +   +G
Sbjct:  260 RCTLCNERLEDTHFVQCPTVSIHKFCFPCSRSSIK----------DQCKSSDMYCPSGDKCPLVGSAMPWAFMQGEIAQILGDEYDEFKRTREAHGLAPPMG 351
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Fly
Match: Pits (gene:FBgn0030400 transcript:FBtr0331718)

HSP 1 Score: 98.5969 bits (244), Expect = 3.121e-21
Identity = 41/63 (65.08%), Postives = 51/63 (80.95%), Query Frame = 3 
Query:  438 SQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK-FEFASHFRRNEQ 623
            ++RQHCYLCDLPR PWAM+ DFSE VCRGCVNYEGADRIE+V++ A+ MK    AS  +R+ +
Sbjct:    5 TKRQHCYLCDLPRMPWAMINDFSEAVCRGCVNYEGADRIEAVLDAARQMKRLHPASKQQRSHE 67

HSP 2 Score: 82.4185 bits (202), Expect = 4.787e-16
Identity = 37/89 (41.57%), Postives = 55/89 (61.80%), Query Frame = 3 
Query: 1566 RCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNKEIK 1832
            +C  C  +LE THFVQCP+   HKFCF C+R  +++ + + +         E+YCPS ++C L  S  PW+F+Q EI TIL G+  ++K
Sbjct:  502 KCTLCQERLEDTHFVQCPSVNHHKFCFPCSRESIKRQNGLGN---------EVYCPSGDRCPLANSVIPWAFMQGEITTIL-GEEVKVK 580
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Fly
Match: Pits (gene:FBgn0030400 transcript:FBtr0273245)

HSP 1 Score: 98.5969 bits (244), Expect = 3.362e-21
Identity = 41/63 (65.08%), Postives = 51/63 (80.95%), Query Frame = 3 
Query:  438 SQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK-FEFASHFRRNEQ 623
            ++RQHCYLCDLPR PWAM+ DFSE VCRGCVNYEGADRIE+V++ A+ MK    AS  +R+ +
Sbjct:    5 TKRQHCYLCDLPRMPWAMINDFSEAVCRGCVNYEGADRIEAVLDAARQMKRLHPASKQQRSHE 67

HSP 2 Score: 82.4185 bits (202), Expect = 5.557e-16
Identity = 37/89 (41.57%), Postives = 55/89 (61.80%), Query Frame = 3 
Query: 1566 RCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNKEIK 1832
            +C  C  +LE THFVQCP+   HKFCF C+R  +++ + + +         E+YCPS ++C L  S  PW+F+Q EI TIL G+  ++K
Sbjct:  547 KCTLCQERLEDTHFVQCPSVNHHKFCFPCSRESIKRQNGLGN---------EVYCPSGDRCPLANSVIPWAFMQGEITTIL-GEEVKVK 625
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Fly
Match: Pits (gene:FBgn0030400 transcript:FBtr0073662)

HSP 1 Score: 98.5969 bits (244), Expect = 3.400e-21
Identity = 41/63 (65.08%), Postives = 51/63 (80.95%), Query Frame = 3 
Query:  438 SQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK-FEFASHFRRNEQ 623
            ++RQHCYLCDLPR PWAM+ DFSE VCRGCVNYEGADRIE+V++ A+ MK    AS  +R+ +
Sbjct:    5 TKRQHCYLCDLPRMPWAMINDFSEAVCRGCVNYEGADRIEAVLDAARQMKRLHPASKQQRSHE 67

HSP 2 Score: 82.4185 bits (202), Expect = 4.957e-16
Identity = 37/89 (41.57%), Postives = 55/89 (61.80%), Query Frame = 3 
Query: 1566 RCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNKEIK 1832
            +C  C  +LE THFVQCP+   HKFCF C+R  +++ + + +         E+YCPS ++C L  S  PW+F+Q EI TIL G+  ++K
Sbjct:  532 KCTLCQERLEDTHFVQCPSVNHHKFCFPCSRESIKRQNGLGN---------EVYCPSGDRCPLANSVIPWAFMQGEITTIL-GEEVKVK 610
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Zebrafish
Match: irf2bp1 (interferon regulatory factor 2 binding protein 1 [Source:NCBI gene;Acc:556852])

HSP 1 Score: 98.5969 bits (244), Expect = 4.345e-21
Identity = 43/85 (50.59%), Postives = 56/85 (65.88%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF CTR+++R+    +          E+YCPS EKC L GS+ PW+F+Q EI+TIL+GD K
Sbjct:  524 CTICQERLEDTHFVQCPSVAGHKFCFPCTRDFIRRQGPGS----------EVYCPSGEKCPLVGSNVPWAFMQGEISTILAGDVK 598

HSP 2 Score: 84.3445 bits (207), Expect = 1.341e-16
Identity = 36/74 (48.65%), Postives = 46/74 (62.16%), Query Frame = 3 
Query:  453 CYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMKFEFASHFRRNEQILQNNANNGTTIQANHN 674
            CYLCDLP+ PWAM+ DFSE VCRGCVNYEGADRIE +I+ A+ +K            ++Q+  + G      H 
Sbjct:   14 CYLCDLPKMPWAMIWDFSEAVCRGCVNYEGADRIELLIDTARQLK---------RTHVMQDGRSPGPQPGGKHG 78
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Zebrafish
Match: irf2bp2a (interferon regulatory factor 2 binding protein 2a [Source:NCBI gene;Acc:335866])

HSP 1 Score: 93.5893 bits (231), Expect = 7.249e-21
Identity = 40/57 (70.18%), Postives = 47/57 (82.46%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            SS+ +  S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADRIE VIE A+ +K
Sbjct:    2 SSAAVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARQLK 58
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Zebrafish
Match: irf2bp2b (interferon regulatory factor 2 binding protein 2b [Source:NCBI gene;Acc:406614])

HSP 1 Score: 95.5153 bits (236), Expect = 2.913e-20
Identity = 46/97 (47.42%), Postives = 60/97 (61.86%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMKFEFASHFRRNEQILQNNANNGTTIQANHNQTFNSLSPNPI 707
            SS+ +  S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADRIE VIE A+ +K        R+   +      G  +Q+ ++    S  P P+
Sbjct:    2 SSAAVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARQLKRAHGFQEGRSPGPV---GKPGKDMQSINHAEPGSRPPQPL 95

HSP 2 Score: 92.4337 bits (228), Expect = 2.661e-19
Identity = 41/85 (48.24%), Postives = 53/85 (62.35%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  +++  +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  420 CTLCHERLEDTHFVQCPSVPSHKFCFPCSRESIKQQGATG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 494
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Zebrafish
Match: irf2bpl (interferon regulatory factor 2 binding protein-like [Source:ZFIN;Acc:ZDB-GENE-040426-1968])

HSP 1 Score: 93.5893 bits (231), Expect = 1.842e-19
Identity = 40/57 (70.18%), Postives = 48/57 (84.21%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            SS+ ++ S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADRIE VIE A+ +K
Sbjct:    2 SSAQVSSSRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARHLK 58

HSP 2 Score: 91.6633 bits (226), Expect = 9.203e-19
Identity = 41/85 (48.24%), Postives = 52/85 (61.18%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  ++   +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  580 CTICHERLEDTHFVQCPSVPNHKFCFPCSRESIKAQGATG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 654
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Xenopus
Match: irf2bp2 (interferon regulatory factor 2 binding protein 2 [Source:NCBI gene;Acc:394851])

HSP 1 Score: 93.9745 bits (232), Expect = 1.638e-19
Identity = 40/57 (70.18%), Postives = 47/57 (82.46%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            SS+ +  S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADRIE VIE A+ +K
Sbjct:    2 SSATVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARHLK 58

HSP 2 Score: 92.4337 bits (228), Expect = 4.870e-19
Identity = 47/110 (42.73%), Postives = 60/110 (54.55%), Query Frame = 3 
Query: 1518 SDIGFESGDNTSVVKAR--------CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            S  G E G   S+  +         C  C  +LE THFVQCP+   HKFCF C+R  +++  S            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  431 SHAGMEQGHPQSIPDSSIPNSIPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGSSG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 530
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Xenopus
Match: suco (SUN domain containing ossification factor [Source:Xenbase;Acc:XB-GENE-965479])

HSP 1 Score: 92.8189 bits (229), Expect = 4.928e-19
Identity = 41/85 (48.24%), Postives = 53/85 (62.35%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R+ ++   +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  609 CTICHERLEDTHFVQCPSVPSHKFCFPCSRDSIKAQGATG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 683

HSP 2 Score: 92.4337 bits (228), Expect = 8.104e-19
Identity = 38/57 (66.67%), Postives = 48/57 (84.21%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            S++ ++ S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADRIE VI+ A+ +K
Sbjct:    2 SAAQVSSSRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIDTARQLK 58
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Mouse
Match: Irf2bpl (interferon regulatory factor 2 binding protein-like [Source:MGI Symbol;Acc:MGI:2442463])

HSP 1 Score: 94.3597 bits (233), Expect = 1.456e-19
Identity = 40/57 (70.18%), Postives = 48/57 (84.21%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            S++ ++ S+RQ CYLCDLPR PWAM+ DFSE VCRGCVNYEGADRIE VIE A+ +K
Sbjct:    2 SAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLK 58

HSP 2 Score: 92.0485 bits (227), Expect = 9.291e-19
Identity = 41/85 (48.24%), Postives = 52/85 (61.18%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  ++   +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  694 CTICHERLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 768
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Mouse
Match: Irf2bp1 (interferon regulatory factor 2 binding protein 1 [Source:MGI Symbol;Acc:MGI:2442159])

HSP 1 Score: 92.8189 bits (229), Expect = 3.327e-19
Identity = 41/85 (48.24%), Postives = 52/85 (61.18%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R +++                E+YCPS +KC L GSS PW+F+Q EI TIL+GD K
Sbjct:  503 CTLCRERLEDTHFVQCPSVPGHKFCFPCSREFIKAQGPAG----------EVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIK 577

HSP 2 Score: 87.0409 bits (214), Expect = 2.011e-17
Identity = 35/53 (66.04%), Postives = 44/53 (83.02%), Query Frame = 3 
Query:  429 MNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            +  S+RQ CYLCDLP+ PWAM+ DFSE VCRGCVN+EGADRIE +I+ A+ +K
Sbjct:    4 VQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLK 56
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Mouse
Match: Irf2bp2 (interferon regulatory factor 2 binding protein 2 [Source:MGI Symbol;Acc:MGI:2443921])

HSP 1 Score: 92.4337 bits (228), Expect = 4.223e-19
Identity = 37/50 (74.00%), Postives = 43/50 (86.00%), Query Frame = 3 
Query:  438 SQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADR+E VIE A+ +K
Sbjct:   11 SRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLK 60

HSP 2 Score: 92.0485 bits (227), Expect = 5.501e-19
Identity = 41/85 (48.24%), Postives = 53/85 (62.35%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  +++  +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  489 CTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 563
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. UniProt/SwissProt
Match: sp|Q1LV17|I2BP1_DANRE (Interferon regulatory factor 2-binding protein 1 OS=Danio rerio OX=7955 GN=irf2bp1 PE=2 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 3.280e-20
Identity = 43/85 (50.59%), Postives = 56/85 (65.88%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF CTR+++R+    +          E+YCPS EKC L GS+ PW+F+Q EI+TIL+GD K
Sbjct:  524 CTICQERLEDTHFVQCPSVAGHKFCFPCTRDFIRRQGPGS----------EVYCPSGEKCPLVGSNVPWAFMQGEISTILAGDVK 598

HSP 2 Score: 84.3445 bits (207), Expect = 1.012e-15
Identity = 36/74 (48.65%), Postives = 46/74 (62.16%), Query Frame = 3 
Query:  453 CYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMKFEFASHFRRNEQILQNNANNGTTIQANHN 674
            CYLCDLP+ PWAM+ DFSE VCRGCVNYEGADRIE +I+ A+ +K            ++Q+  + G      H 
Sbjct:   14 CYLCDLPKMPWAMIWDFSEAVCRGCVNYEGADRIELLIDTARQLK---------RTHVMQDGRSPGPQPGGKHG 78
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. UniProt/SwissProt
Match: sp|Q7T2G1|I2B2B_DANRE (Interferon regulatory factor 2-binding protein 2-B OS=Danio rerio OX=7955 GN=irf2bp2b PE=2 SV=1)

HSP 1 Score: 95.5153 bits (236), Expect = 2.320e-19
Identity = 46/97 (47.42%), Postives = 60/97 (61.86%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMKFEFASHFRRNEQILQNNANNGTTIQANHNQTFNSLSPNPI 707
            SS+ +  S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADRIE VIE A+ +K        R+   +      G  +Q+ ++    S  P P+
Sbjct:    2 SSAAVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARQLKRAHGFQEGRSPGPV---GKPGKDMQSINHAEPGSRPPQPL 95

HSP 2 Score: 92.4337 bits (228), Expect = 2.082e-18
Identity = 41/85 (48.24%), Postives = 53/85 (62.35%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  +++  +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  420 CTLCHERLEDTHFVQCPSVPSHKFCFPCSRESIKQQGATG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 494
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. UniProt/SwissProt
Match: sp|Q6NZT6|I2B2A_DANRE (Interferon regulatory factor 2-binding protein 2-A OS=Danio rerio OX=7955 GN=irf2bp2a PE=2 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 6.132e-19
Identity = 40/57 (70.18%), Postives = 47/57 (82.46%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            SS+ +  S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADRIE VIE A+ +K
Sbjct:    2 SSAAVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARQLK 58

HSP 2 Score: 91.6633 bits (226), Expect = 3.228e-18
Identity = 41/85 (48.24%), Postives = 53/85 (62.35%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  +++  +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  410 CTLCHERLEDTHFVQCPSVPSHKFCFPCSRESIKQQGATG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 484
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. UniProt/SwissProt
Match: sp|Q7ZXS3|I2BP2_XENLA (Interferon regulatory factor 2-binding protein 2 OS=Xenopus laevis OX=8355 GN=irf2bp2 PE=2 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 8.157e-19
Identity = 40/57 (70.18%), Postives = 47/57 (82.46%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            SS+ +  S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADRIE VIE A+ +K
Sbjct:    2 SSATVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARHLK 58

HSP 2 Score: 92.0485 bits (227), Expect = 3.709e-18
Identity = 42/85 (49.41%), Postives = 53/85 (62.35%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  +++  S            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  456 CTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGSSG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 530
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. UniProt/SwissProt
Match: sp|Q6DIH5|I2BP2_XENTR (Interferon regulatory factor 2-binding protein 2 OS=Xenopus tropicalis OX=8364 GN=irf2bp2 PE=2 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 8.680e-19
Identity = 40/57 (70.18%), Postives = 47/57 (82.46%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            SS+ +  S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADRIE VIE A+ +K
Sbjct:    2 SSATVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARHLK 58

HSP 2 Score: 92.4337 bits (228), Expect = 2.580e-18
Identity = 47/110 (42.73%), Postives = 60/110 (54.55%), Query Frame = 3 
Query: 1518 SDIGFESGDNTSVVKAR--------CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            S  G E G   S+  +         C  C  +LE THFVQCP+   HKFCF C+R  +++  S            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  431 SHAGMEQGHPQSIPDSSIPNSIPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGSSG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 530
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. TrEMBL
Match: V3Z9Q6 (IRF-2BP1_2 domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_219852 PE=4 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 3.727e-48
Identity = 145/498 (29.12%), Postives = 230/498 (46.18%), Query Frame = 3 
Query:  423 SLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMKFEFASHFRRNEQILQNNANNGTTIQANHNQTFNSLSPNPISIDNQFFFKSSNS--QTGXXXXXXXXXXXXXXXEATIRSLAAGILPQLFPSIKIVGRNGEQDEGSLIA-----IETVDIINRSCPFLVRCSILPTIKAVVMKADMKP---ITNEI------ADTGIHYELILNFEFPISSGNYLFGFDAFWNHLVADFDSTSSSLLEANAGTDKILASIEYELKPNSNLWEKLNSWLTYSVTLFKERLTHDSNLIPQRNTVYKYKSNYLSIKNHKINK-----LSTTTNFRKRKEYSCSSPPNKLYSQRKSFSPREIGKNRIKFPFESSFQSDIGFESGDNTSVVKARCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNKEIKTSPKLFN 1853
            S+ + SQRQHCYLCDLPR PWAML DFSE VCRGCVNYEG DRIE VI+ A+ MK    SH     Q + +  + G ++ A H     S   + ++ +N   +  +++         +    L       ++  L A  LP++  ++ I   NG    GS++        + + +N + P  VR ++   +  V  K   K    +T  +       +  + YEL +  E+P+ SG+     +     +  D       L +        L  +EYE+K  S+ W   + +LT  V +FKE +  +  +IP     +   ++  +   H  +      ++ T N  K    S       L S R    P  +    I     S  +S +      N+  +  RC  C  +LE THFVQCP+  EHKFCF C+++ +++  + +          E+YCPS++KC L GSS PW+F+  EI TIL    +++K   ++ N
Sbjct:    2 SMPHRSQRQHCYLCDLPRTPWAMLHDFSEAVCRGCVNYEGPDRIEMVIDAARQMK---RSH---GVQEIHSKYSAGVSVGAIHGPRAVS---SAVNNNNAVGYPDTSAYNMEPPNARMHHGHLPTSPERFSMHELRARSLPEVGSNMAIRPTNGI---GSVVGHTNSSASSSEELNINRPLAVRETLSVLMTCVPFKVRFKKDHLLTGRVFTFDACLNANMTYELKVFIEYPLGSGSIYSSANGVVKQMYQD------CLKDLGKNLSFGLKYLEYEMKQGSSDWRVFSDFLTDGVRIFKEPVKKE--MIPSSPVGHPAPTSPDTAVPHSESSPMTALMTATKNLTKTSSVSEGQSSKTLVSSRVHSLPGPVSDAGIGSTSSSMPESTV-----PNSEAL--RCTICEERLEDTHFVQCPSVIEHKFCFPCSKDSIKRQGAGS----------EVYCPSNKKCPLAGSSVPWAFMPGEIVTILGEQYRDVKVKKEVEN 462
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. TrEMBL
Match: A0A060VZE3 (IRF-2BP1_2 domain-containing protein OS=Oncorhynchus mykiss OX=8022 GN=GSONMT00077575001 PE=4 SV=1)

HSP 1 Score: 161.384 bits (407), Expect = 2.545e-39
Identity = 144/517 (27.85%), Postives = 200/517 (38.68%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIE---QAKSMKFEFASHFRRNEQILQNNANNGTTIQANHNQTFNSLSPNPISIDNQFFFKSSNSQTGXXXXXXXXXXXXXXXEATIRSLAAGILPQLFPSIKIVGRNGE-----------QDEG----SLIAIETVDIINRSCPFLVRCSILPTIKAVVMKADMKPITNEIADTGIHYELILNFEFPISSGNYLFGFDAFWNHLVADFDSTSSSLLEANAGTDKILASIEYELKPNSNLWEKLNSWLTYSVTLFKERLTHDSNLIPQRNTVYKYKSNYLSIKNHKINKLSTTTNFRKRKEYSCSSPPNKLYSQRKSFSPREIGKNRIKFPFESSFQSD-------------------------------IGFESGDNTSVVKARCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDN 1820
            SS+    S+RQ CYLCDLP+ PWAML +FSE VCRGCVNY+GADRIE +IE   Q KS           N +     A         H      L   P  +        +  Q    ++  +   ++     +  SL AG        ++   RNGE           + EG      +  E +  +    PF VR      +   ++  +        A  G  +EL +  E+P  SG    G       +  D +       +A    +  L  +EYE + ++  W  L   L+  V  FKE    D  ++PQ                +    +      R       S+PP     +RK+    E G+N    P  SS  S                                +G ESG  T      C  C  +LE THFVQCP+   HKFCF CTR  +R                E+YCPS E+C L GS+ PW+F+Q EI+TIL+GD 
Sbjct:    2 SSASQTSSRRQWCYLCDLPKMPWAMLWEFSEAVCRGCVNYDGADRIELLIETARQLKSSHGVLDGRQSPNTRRAMAGAIPALHGTIPHALIAQGLVGPPHGLLAPVLGTRAGGQQIAGSSGPIMGDVSRRQVVSAMSLGAGA--SALVGLEAGWRNGEVMAELAESARSRAEGWPNRPKVVREVLVTLCGCAPFSVRFRKDHNLVGRILAFE--------AGAGPEFELKVFVEYPSGSGIVFSGITELVRQMFRDSNK------DAGKAVNSGLRYVEYERRQSAGDWRALTELLSDGVRSFKEPPMPD--VLPQL---------------YADGGMPMVPAVR-------SAPPKGAARRRKASPGSENGEN---GPGMSSAHSSASGRPTSGSPSSASAAVSQAVMGQGGPSTTSVG-ESGSGTPSALLCCTLCRERLEDTHFVQCPSVPHHKFCFPCTRGSIRSQGP----------GGEVYCPSGERCPLAGSTVPWAFMQGEISTILAGDG 464
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. TrEMBL
Match: A0A4W5M0B4 (Interferon regulatory factor 2 binding protein-like OS=Hucho hucho OX=62062 PE=4 SV=1)

HSP 1 Score: 159.844 bits (403), Expect = 2.560e-38
Identity = 156/572 (27.27%), Postives = 224/572 (39.16%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMKFEFASHFRRN-----------------EQILQNNANNGTTIQANHNQTFNSLS------------------PNPISIDNQFFFKSSNSQTGXXXXXXXXXXXXXXXEATIRSLAAGILPQLFPSIKIVGRNGEQDEGSLIAIETVDIINRSCPFLVRCSILPTIKAVVMKADMKPITNEIADTGIHYELILNFEFPISSGNYLFGFDAFWNHLVADFDSTSSSLLEANAGTDKILASIEYELKPNSNLWEKLNSWLTYSVTLFKERLTHDSNLIPQ---RNTVYKYKSNYLSIKNHKINKLSTTTNFRKRKEYSCSSPPNKLYS---------QRKSFSPREIGKNRIKFPFES--SFQSDIG--FESGDNTSV----------------------VKARCRNCSIKLEGT------------------------------HFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            SS+ ++ S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADRIE VIE A+ +K        R+                 ++ +Q +  +G + Q        SLS                  PN + ++ Q    S NS+             +   +   +   A  L +L  S++   RN +      I  +T+  ++ S PF VR     ++   V   D       ++  G+ YEL +  E+P  SGN           +  D       + +   G       +EYE K  S  W  L   L  SV  FKE L  +  ++PQ     +     +  ++I     +  +  T  RKRK    S  P+ + S         QR   +P E      + P  +  S    +G      DN SV                       +   RN  + L GT                              HFVQCP+   HKFCF C+R  ++   +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:    2 SSAQVSSSRRQSCYLCDLPRMPWAMIWDFTEAVCRGCVNYEGADRIEFVIETARHLKRAHGFQGGRSPGPPPPPTVKTQSAISAKETVQISHVDGPSKQQQSGMDRYSLSAERPRFDYSSIGAHASRLPNGMKLNRQ----SPNSR----KRPGSVSSTDQERDLKEKQRNAEALAELSESLR--NRNEDWGNKPKIVRDTLVTLSNSSPFDVRFKKDHSLVGRVFAFDA------VSKPGMDYELKIFVEYPSGSGNIFSSASGVAKQMYQD------CMKDFGRGLSSGFKYLEYEKKHGSGDWRLLGDLLPESVRFFKEGLGVE--MLPQPYIDASCPLLPTALVNIPRALPSTSAPRTGVRKRK---ASPEPDSVESALKLSEQEQQRHRATPPESAPQNGQSPMAALMSVADTLGNAHSPKDNNSVHSTTSTRHNSSSPVSPASVSGQRRLASRNGELNLAGTPSQSNAHSDSPMANNGPLCCTICHERLEDTHFVQCPSVPNHKFCFPCSRESIKAQGATG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 536
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. TrEMBL
Match: A0A401RDZ8 (IRF-2BP1_2 domain-containing protein OS=Chiloscyllium punctatum OX=137246 GN=chiPu_0022196 PE=4 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 5.438e-22
Identity = 99/331 (29.91%), Postives = 135/331 (40.79%), Query Frame = 3 
Query:  939 PFLVRCSILPTIKAVVMKADMKPITNEIADTGIHYELILNFEFPISSGNYLFGFDAFWNHLVADFDSTSSSLLEANAGTDKILASIEYELKPNSNLWEKLNSWLTYSVTLFKERLTHDSNLIPQRNTVYKYKSNYLSIKNHKINKLSTTTNFRKRK----EYSCSS-PPNK-----------LYSQRKSFSPREIGKNRIKFPFESSFQSDIGFE--------------------SGDNTSVVKARCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            PF +R    P+++A V+  D         D  +  EL L  E+P  SG    G      H++AD      S  EA A     L  +EYE +P +  W  L+  LT +  LFKE +  D  L+P+      +    LS           +   R+RK      +C   PP +             S      P+E   +    P +    S  G E                       ++S     C  C  +LE THFVQCP+   HKFCF C+R       S+ S   N     E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  215 PFPLRLRAEPSLQARVLAFDA---AERCPDRAL--ELRLFIEYPSGSGAVHSGVAEAVRHMLAD------SAKEAQAPG---LECLEYERRPGAGDWRPLSHLLTEAARLFKEAVPAD--LLPE-----PHAEPGLSRPPPPPTTSRPSGPARRRKASPEPEACKGLPPGEPQAWPPEGHSPAGSSADPLLPKEAVHSTTAPPGQRRLTSRNGGEVEPGAEPPPPQPPPPAAPSAGAPDSSSSPLCCTICHQRLEDTHFVQCPSVPGHKFCFPCSRE------SIKSQGANG----EVYCPSGEKCPLIGSNVPWAFMQGEIATILAGDIK 514

HSP 2 Score: 87.8113 bits (216), Expect = 2.263e-14
Identity = 36/49 (73.47%), Postives = 41/49 (83.67%), Query Frame = 3 
Query:  441 QRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            +R  CYLCDLPR PWAM+ DFS+ VCRGCVNYEGADRIE VIEQ + +K
Sbjct:   18 RRHSCYLCDLPRMPWAMIWDFSQAVCRGCVNYEGADRIELVIEQTRHLK 66
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. TrEMBL
Match: A0A1B0DEH1 (IRF-2BP1_2 domain-containing protein OS=Phlebotomus papatasi OX=29031 PE=4 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 1.125e-21
Identity = 45/82 (54.88%), Postives = 59/82 (71.95%), Query Frame = 3 
Query:  438 SQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMKFEFASHFRRNEQILQNNANNGTTIQANHNQTF 683
            ++RQHCYLCDLPR PWAM+ DFSE VCRGCVNYEGADRIE V++ A+ MK   ++  R +E      A+ G  + A+H+ T+
Sbjct:    5 TKRQHCYLCDLPRMPWAMIHDFSEAVCRGCVNYEGADRIELVLDTARQMKRAHSAGKRAHENGEVAAAHRG--VPASHHHTY 84
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Cavefish
Match: irf2bp1 (interferon regulatory factor 2 binding protein 1 [Source:NCBI gene;Acc:556852])

HSP 1 Score: 98.2117 bits (243), Expect = 5.237e-21
Identity = 53/140 (37.86%), Postives = 72/140 (51.43%), Query Frame = 3 
Query: 1413 SCSSPPNKLYSQRKSFSPREIGKNRIKFPFESSFQSDIGFESGDNTSVVKAR---CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            S SS   +  + R    P   G   +          D G  +G + S   +    C  C  +LE THFVQCP+   HKFCF CTR+++R   S +          E+YCPS +KC L GS+ PW+F+Q EI+TIL+GD K
Sbjct:  437 SPSSAGQRRLASRNGEPPAGSGGAAVATAMPPGGAGDQGAVTGVDASGAGSAPLCCTICHERLEDTHFVQCPSVPGHKFCFPCTRDFIRSQGSGS----------EVYCPSGDKCPLVGSNVPWAFMQGEISTILAGDVK 566

HSP 2 Score: 84.7297 bits (208), Expect = 7.977e-17
Identity = 36/74 (48.65%), Postives = 46/74 (62.16%), Query Frame = 3 
Query:  453 CYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMKFEFASHFRRNEQILQNNANNGTTIQANHN 674
            CYLCDLP+ PWAM+ DFSE VCRGCVNYEGADRIE +I+ A+ +K            ++Q+  + G      H 
Sbjct:   15 CYLCDLPKMPWAMIWDFSEAVCRGCVNYEGADRIELLIDTARQLK---------RTHVMQDGRSPGPQPSGKHG 79
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Cavefish
Match: irf2bpl (interferon regulatory factor 2 binding protein-like [Source:ZFIN;Acc:ZDB-GENE-040426-1968])

HSP 1 Score: 97.4413 bits (241), Expect = 1.209e-20
Identity = 47/87 (54.02%), Postives = 58/87 (66.67%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMKFEFASHFRRNEQILQNNANNG--TTIQANH 671
            SS+ +  S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADRIE VIE A+ +K        R+        ++G  TT+Q NH
Sbjct:    2 SSAQVASSRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARHLKRAHGFQDGRSPGPGGAGVSHGKETTVQLNH 88

HSP 2 Score: 91.2781 bits (225), Expect = 1.084e-18
Identity = 41/85 (48.24%), Postives = 52/85 (61.18%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  ++   +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  588 CTICHERLEDTHFVQCPSVPGHKFCFPCSRESIKAQGATG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 662
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Cavefish
Match: irf2bp2b (interferon regulatory factor 2-binding protein 2-B-like [Source:NCBI gene;Acc:103039790])

HSP 1 Score: 95.1301 bits (235), Expect = 4.083e-20
Identity = 40/57 (70.18%), Postives = 47/57 (82.46%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            SS+ +  S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADRIE VIE A+ +K
Sbjct:    2 SSAAVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARQLK 58

HSP 2 Score: 92.8189 bits (229), Expect = 2.189e-19
Identity = 41/85 (48.24%), Postives = 53/85 (62.35%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  +++  +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  440 CTLCHERLEDTHFVQCPSVPSHKFCFPCSRESIKQQGATG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 514
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Cavefish
Match: irf2bp2a (interferon regulatory factor 2-binding protein 2-A-like [Source:NCBI gene;Acc:103028822])

HSP 1 Score: 92.0485 bits (227), Expect = 2.972e-19
Identity = 41/85 (48.24%), Postives = 53/85 (62.35%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  +++  +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  420 CTLCHERLEDTHFVQCPSVSSHKFCFPCSRESIKQQGATG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 494

HSP 2 Score: 92.0485 bits (227), Expect = 2.999e-19
Identity = 38/50 (76.00%), Postives = 43/50 (86.00%), Query Frame = 3 
Query:  438 SQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            S+RQ CYLCDLPR PWAM+ DF+E VCRGCVNYEGADRIE VIE A+ +K
Sbjct:   10 SRRQSCYLCDLPRMPWAMIWDFTEAVCRGCVNYEGADRIEFVIETARQLK 59
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Nematostella
Match: EDO43062 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZW7])

HSP 1 Score: 102.834 bits (255), Expect = 6.328e-24
Identity = 90/318 (28.30%), Postives = 133/318 (41.82%), Query Frame = 3 
Query:  903 AIETVDIINRSCPFLVRCSILPTI--KAVVMKADMKPITNEIADTGIHYELILNFEFPISSGNYLFGFDAFWNHLVADFDSTSSSLLEANAGTDKI--LASIEYELKPNSNLWEKLNSWLTYSVTLFKERLTHDSNLIPQRNTVYKYKSNYLSIKNHKINKLSTTTNFRKRKEYSCSSPPNKLYSQRKSFSPREIGKNRI------KFP-----FESSFQSDIGFESGDNTSVVKARCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILS 1811
            A  T+ ++NRS PF +R     T   +  V   + KP        G+ +EL +  E+P  SG             VA       S L  + G      +  +EYE    +  W  L   L  SV  FKE +  +    PQ ++ Y   +  +   +     +    +  K    + S+PP    S   S S   +    I      + P       +  +S I        S++  RC  C  KLE THFVQCP+   HKFCF C+R+ ++K  + T          E++CPS E+C L GS+ PW+F+Q EI TIL 
Sbjct:   33 AHATLSLLNRSVPFDIRFKKDHTSIGRIFVFDVNNKP--------GLEFELKIFIEYPRGSGCVF--------QSVAGVVKKMHSELHKDIGRTHTSGVKYLEYEKDRGTGDWRMLADLLPESVRYFKEPVKQELLPRPQLDSEYPLPNETM---HQHPAWVQNQVDGGKLVMTAMSAPPGTPVSSIPSASVSPMVTTPISKVASMQLPPSEVHVRAQSKSPINNSGSSGQSIL--RCSLCRDKLEDTHFVQCPSIMHHKFCFPCSRDSIKKQGAGT----------EVFCPSGERCPLQGSNLPWAFMQGEIQTILG 319
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Medaka
Match: irf2bp2a (interferon regulatory factor 2 binding protein 2 [Source:NCBI gene;Acc:101169386])

HSP 1 Score: 92.0485 bits (227), Expect = 3.694e-19
Identity = 41/85 (48.24%), Postives = 53/85 (62.35%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  +++  +            E+YCPS EKC L GS+ PW+F+Q EI TIL+GD K
Sbjct:  422 CTLCHERLEDTHFVQCPSVPSHKFCFPCSRESIKQQGATG----------EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVK 496

HSP 2 Score: 90.8929 bits (224), Expect = 7.593e-19
Identity = 38/49 (77.55%), Postives = 42/49 (85.71%), Query Frame = 3 
Query:  441 QRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            +RQ CYLCDLPR PWAML DFSE VCRGCVNYEGADRIE VI+ A+ +K
Sbjct:   11 RRQSCYLCDLPRMPWAMLWDFSEPVCRGCVNYEGADRIEIVIDSARHLK 59
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Medaka
Match: ENSORLT00000001480.2 (interferon regulatory factor 2-binding protein 2-B [Source:NCBI gene;Acc:101171800])

HSP 1 Score: 91.2781 bits (225), Expect = 6.474e-19
Identity = 40/85 (47.06%), Postives = 53/85 (62.35%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNK 1823
            C  C  +LE THFVQCP+   HKFCF C+R  +++  +            E+YCPS E+C L GS+ PW+F+Q EI TIL+GD K
Sbjct:  424 CTLCHERLEDTHFVQCPSVPSHKFCFPCSRESIKQQGATG----------EVYCPSGERCPLVGSNVPWAFMQGEIATILAGDIK 498

HSP 2 Score: 90.5077 bits (223), Expect = 9.156e-19
Identity = 39/57 (68.42%), Postives = 46/57 (80.70%), Query Frame = 3 
Query:  417 SSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            SS+ +  S+RQ CYLCDLPR  WAM+ DF+E VCRGCVNYEGADRIE VIE A+ +K
Sbjct:    2 SSAAVAASRRQSCYLCDLPRMQWAMIWDFTEPVCRGCVNYEGADRIEIVIESARHLK 58
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Medaka
Match: irf2bp1 (interferon regulatory factor 2 binding protein 1 [Source:NCBI gene;Acc:556852])

HSP 1 Score: 82.8037 bits (203), Expect = 4.255e-16
Identity = 33/45 (73.33%), Postives = 39/45 (86.67%), Query Frame = 3 
Query:  453 CYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            CYLCDLP+ PWAML +FSE VCRGCVNY+GADRIE +IE A+ +K
Sbjct:   14 CYLCDLPKMPWAMLWEFSEAVCRGCVNYDGADRIELLIETARQLK 58

HSP 2 Score: 58.9214 bits (141), Expect = 1.143e-8
Identity = 25/58 (43.10%), Postives = 31/58 (53.45%), Query Frame = 3 
Query: 1569 CRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSE 1742
            C  C  +LE THFVQCP+   HKFCF CTR ++R                E+YCPS +
Sbjct:  510 CTLCRERLEDTHFVQCPSVPHHKFCFPCTRGFIRSQG----------QGGEVYCPSGD 557
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Medaka
Match: irf2bp1 (interferon regulatory factor 2-binding protein 1-like [Source:NCBI gene;Acc:111948510])

HSP 1 Score: 80.1073 bits (196), Expect = 1.430e-15
Identity = 32/50 (64.00%), Postives = 41/50 (82.00%), Query Frame = 3 
Query:  438 SQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMK 587
            S+RQ CYLCDLP+ PW ++ DFSE VCRGCVNYEGA++IE +I  A+ +K
Sbjct:    7 SRRQWCYLCDLPKMPWTVVWDFSEVVCRGCVNYEGANQIEFLIASARQLK 56

HSP 2 Score: 78.9518 bits (193), Expect = 3.499e-15
Identity = 41/93 (44.09%), Postives = 52/93 (55.91%), Query Frame = 3 
Query: 1536 SGDNTSVVKARCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGS--SSPWSFLQTEINTIL 1808
            SG NT      C  C  +LE THFVQCP+   H+FCF CTR Y++                E+YCPS E+C L  S  S PW+F+Q E++TIL
Sbjct:  307 SGGNT----LSCTLCHERLEDTHFVQCPSVPGHRFCFPCTRVYIQSRR----------GDGEVYCPSGERCPLDNSPNSPPWAFMQGEVSTIL 385
[Close]
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Planmine SMEST
Match: SMESG000042710.1 (SMESG000042710.1)

HSP 1 Score: 993.801 bits (2568), Expect = 0.000e+0
Identity = 496/500 (99.20%), Postives = 498/500 (99.60%), Query Frame = 3 
Query:  384 MSSQFKPKQLYSSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMKFEFASHFRRNEQILQNNANNGTTIQANHNQTFNSLSPNPISIDNQFFFKSSNSQTGXXXXXXXXXXXXXXXEATIRSLAAGILPQLFPSIKIVGRNGEQDEGSLIAIETVDIINRSCPFLVRCSILPTIKAVVMKADMKPITNEIADTGIHYELILNFEFPISSGNYLFGFDAFWNHLVADFDSTSSSLLEANAGTDKILASIEYELKPNSNLWEKLNSWLTYSVTLFKERLTHDSNLIPQRNTVYKYKSNYLSIKNHKINKLSTTTNFRKRKEYSCSSPPNKLYSQRKSFSPREIGKNRIKFPFESSFQSDIGFESGDNTSVVKARCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNKEIKTSPKLFNVVAEVGEDLS 1883
            MSSQFKPKQLYSSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMKFEFASHFRRNEQ+LQNNANNGTTIQANHNQTFNSLSPNPISIDNQFFFKSSNSQTGLFNNLSVQQLLNLSSEATIRSLAAGILPQLFPSIKIVGRNGEQDEGSLIAIETVDIINRSCPFLVRCS+LPTIKAVVMKADMKPI NEIADTGIHYELILNFEFPISSGNYLFGFDAFWNHLVADFDSTSSSLLEANAGTDKILASIEYELKPNSNLWEKLNSWLTYSVTLFKERLTHDSN IPQRNTVYKYKSNYLSIKNHKINKLSTTTNFRKRKEYSCSSPPNKLYSQRKSFSPREIGKNRIKFPFESSFQSDIGFESGDNTSVVKARCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNKEIKTSPKLFNVVAEVGEDLS
Sbjct:    1 MSSQFKPKQLYSSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVNYEGADRIESVIEQAKSMKFEFASHFRRNEQMLQNNANNGTTIQANHNQTFNSLSPNPISIDNQFFFKSSNSQTGLFNNLSVQQLLNLSSEATIRSLAAGILPQLFPSIKIVGRNGEQDEGSLIAIETVDIINRSCPFLVRCSVLPTIKAVVMKADMKPIANEIADTGIHYELILNFEFPISSGNYLFGFDAFWNHLVADFDSTSSSLLEANAGTDKILASIEYELKPNSNLWEKLNSWLTYSVTLFKERLTHDSNFIPQRNTVYKYKSNYLSIKNHKINKLSTTTNFRKRKEYSCSSPPNKLYSQRKSFSPREIGKNRIKFPFESSFQSDIGFESGDNTSVVKARCRNCSIKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCPSSEKCILPGSSSPWSFLQTEINTILSGDNKEIKTSPKLFNVVAEVGEDLS 500
The following BLAST results are available for this feature:
BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
IRF2BPL2.193e-1970.18interferon regulatory factor 2 binding protein lik... [more]
IRF2BP15.529e-1948.24interferon regulatory factor 2 binding protein 1 [... [more]
IRF2BP26.710e-1974.00interferon regulatory factor 2 binding protein 2 [... [more]
IRF2BP26.739e-1974.00interferon regulatory factor 2 binding protein 2 [... [more]
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BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tag-2606.640e-1838.24pep chromosome:WBcel235:V:13370083:13372724:-1 gen... [more]
tag-2606.640e-1838.24pep chromosome:WBcel235:V:13370083:13372897:-1 gen... [more]
tag-2606.640e-1838.24pep chromosome:WBcel235:V:13370083:13372897:-1 gen... [more]
tag-2604.328e-1738.24pep chromosome:WBcel235:V:13370083:13380262:-1 gen... [more]
tag-2604.564e-1766.67pep chromosome:WBcel235:V:13370109:13373020:-1 gen... [more]
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BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Pits3.121e-2165.08gene:FBgn0030400 transcript:FBtr0331718[more]
Pits3.362e-2165.08gene:FBgn0030400 transcript:FBtr0273245[more]
Pits3.400e-2165.08gene:FBgn0030400 transcript:FBtr0073662[more]
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BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
irf2bp14.345e-2150.59interferon regulatory factor 2 binding protein 1 [... [more]
irf2bp2a7.249e-2170.18interferon regulatory factor 2 binding protein 2a ... [more]
irf2bp2b2.913e-2047.42interferon regulatory factor 2 binding protein 2b ... [more]
irf2bpl1.842e-1970.18interferon regulatory factor 2 binding protein-lik... [more]
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BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
irf2bp21.638e-1970.18interferon regulatory factor 2 binding protein 2 [... [more]
suco4.928e-1948.24SUN domain containing ossification factor [Source:... [more]
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BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Irf2bpl1.456e-1970.18interferon regulatory factor 2 binding protein-lik... [more]
Irf2bp13.327e-1948.24interferon regulatory factor 2 binding protein 1 [... [more]
Irf2bp24.223e-1974.00interferon regulatory factor 2 binding protein 2 [... [more]
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BLAST of Interferon regulatory factor 2-binding protein 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q1LV17|I2BP1_DANRE3.280e-2050.59Interferon regulatory factor 2-binding protein 1 O... [more]
sp|Q7T2G1|I2B2B_DANRE2.320e-1947.42Interferon regulatory factor 2-binding protein 2-B... [more]
sp|Q6NZT6|I2B2A_DANRE6.132e-1970.18Interferon regulatory factor 2-binding protein 2-A... [more]
sp|Q7ZXS3|I2BP2_XENLA8.157e-1970.18Interferon regulatory factor 2-binding protein 2 O... [more]
sp|Q6DIH5|I2BP2_XENTR8.680e-1970.18Interferon regulatory factor 2-binding protein 2 O... [more]
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BLAST of Interferon regulatory factor 2-binding protein 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
V3Z9Q63.727e-4829.12IRF-2BP1_2 domain-containing protein OS=Lottia gig... [more]
A0A060VZE32.545e-3927.85IRF-2BP1_2 domain-containing protein OS=Oncorhynch... [more]
A0A4W5M0B42.560e-3827.27Interferon regulatory factor 2 binding protein-lik... [more]
A0A401RDZ85.438e-2229.91IRF-2BP1_2 domain-containing protein OS=Chiloscyll... [more]
A0A1B0DEH11.125e-2154.88IRF-2BP1_2 domain-containing protein OS=Phlebotomu... [more]
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BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
irf2bp15.237e-2137.86interferon regulatory factor 2 binding protein 1 [... [more]
irf2bpl1.209e-2054.02interferon regulatory factor 2 binding protein-lik... [more]
irf2bp2b4.083e-2070.18interferon regulatory factor 2-binding protein 2-B... [more]
irf2bp2a2.972e-1948.24interferon regulatory factor 2-binding protein 2-A... [more]
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BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO430626.328e-2428.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Interferon regulatory factor 2-binding protein 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
irf2bp2a3.694e-1948.24interferon regulatory factor 2 binding protein 2 [... [more]
ENSORLT00000001480.26.474e-1947.06interferon regulatory factor 2-binding protein 2-B... [more]
irf2bp14.255e-1673.33interferon regulatory factor 2 binding protein 1 [... [more]
irf2bp11.430e-1564.00interferon regulatory factor 2-binding protein 1-l... [more]
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BLAST of Interferon regulatory factor 2-binding protein 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000042710.10.000e+099.20SMESG000042710.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002828 ID=SMED30002828|Name=Interferon regulatory factor 2-binding protein 2|organism=Schmidtea mediterranea sexual|type=transcript|length=1954bp
CTCAGTCATTTTTGCATTGATCGACTATATAGAAAACATCGTACAGGGCC
AGTCTATTCGGGCGGAAAAGCAGGAGAATAGGCTAGTGAACGGAAAGTAA
GAGAGGTTTCCGCGTTTTCCAATTTGTCACGAAGTATACGTGAGAAGAAT
CCAGTATGGGCCTCTTATCCACTCGTAACCAGTCACGAAAGGTTGCATGT
TGTTCTAAAAAGAAAGAGAAGTCCTATTTAATTGACGACAACAACAAATA
GTAGTAGTAATAGCAGTCGAAGTGGTCTAGTTCATCTTCAGTAAACTAAA
AATTCAGAATAAAAATTTGCACAATTTTCTTTTCAAAAATTTCTTGTTTA
CTATGGGATTTATGTTTTCAATTTAAAAAAAATATGTCATCTCAGTTCAA
ACCGAAACAACTCTATTCTTCAAGTTTGATGAATTATTCACAGCGACAAC
ATTGCTATTTGTGTGATCTTCCTCGCTATCCGTGGGCAATGCTGCAAGAT
TTTAGTGAATTCGTTTGCCGAGGATGTGTCAATTATGAAGGCGCTGATCG
AATTGAATCGGTTATAGAACAAGCGAAATCTATGAAATTTGAATTTGCTT
CTCATTTTAGAAGAAATGAACAGATATTACAGAATAATGCTAACAATGGG
ACAACTATTCAAGCAAACCATAATCAAACATTCAACAGTTTATCGCCGAA
TCCGATTTCAATTGACAATCAGTTCTTTTTCAAATCCTCTAACTCCCAGA
CTGGACTCTTTAATAACTTATCGGTGCAGCAATTGTTGAATTTATCCTCG
GAGGCCACGATTCGTTCATTGGCAGCTGGGATTTTACCGCAATTGTTTCC
TTCTATTAAAATAGTCGGAAGAAACGGAGAACAAGACGAAGGTTCTTTGA
TTGCTATTGAAACTGTTGATATAATCAATCGGTCTTGTCCTTTTTTAGTA
CGATGTTCAATTCTTCCTACAATAAAGGCTGTTGTTATGAAGGCTGACAT
GAAGCCGATAACGAATGAAATTGCTGATACTGGGATTCACTATGAGTTGA
TATTAAATTTCGAATTTCCCATTAGTTCAGGAAATTATTTATTTGGCTTC
GATGCTTTCTGGAACCATTTGGTAGCTGATTTCGATTCAACAAGCAGTTC
TTTATTAGAAGCTAATGCTGGAACGGATAAAATACTTGCTAGCATTGAAT
ATGAACTTAAACCCAATAGTAATTTATGGGAGAAGCTTAATTCATGGCTT
ACTTATTCAGTTACATTATTCAAAGAACGCTTGACTCACGATTCCAATCT
TATTCCACAAAGAAATACCGTTTACAAATACAAGTCCAATTATTTGTCAA
TTAAAAACCACAAAATTAACAAATTAAGCACAACAACAAATTTTCGAAAA
AGAAAAGAATATTCCTGTTCATCGCCACCGAATAAATTATATTCTCAACG
GAAATCTTTCAGTCCCCGAGAAATAGGTAAAAATCGAATCAAATTTCCAT
TTGAAAGTTCTTTTCAATCCGATATTGGTTTTGAATCAGGTGATAATACT
TCTGTTGTAAAAGCTCGATGTAGAAATTGTTCGATTAAGTTAGAGGGCAC
CCATTTTGTCCAGTGCCCAGCGTTCTGTGAGCACAAATTCTGTTTCGAGT
GCACTCGAAATTACTTACGCAAACATTCATCAGTTACCAGCACAAGTCAT
AATTCGTTGAATTTTGAAGAGATTTATTGCCCGAGCTCTGAAAAATGCAT
TTTGCCAGGATCTTCGTCTCCGTGGTCTTTTCTCCAAACAGAAATAAATA
CCATATTATCTGGAGATAATAAAGAAATTAAAACTTCTCCGAAACTTTTC
AATGTTGTCGCAGAAGTGGGAGAAGATTTATCAATTAATAAGAAAGAGAA
AATAAATGAAGACATATGAAAAATTATGCAATCATTTTGTGGTTTATTAA
ATAT
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protein sequence of SMED30002828-orf-1

>SMED30002828-orf-1 ID=SMED30002828-orf-1|Name=SMED30002828-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=512bp
MSSQFKPKQLYSSSLMNYSQRQHCYLCDLPRYPWAMLQDFSEFVCRGCVN
YEGADRIESVIEQAKSMKFEFASHFRRNEQILQNNANNGTTIQANHNQTF
NSLSPNPISIDNQFFFKSSNSQTGLFNNLSVQQLLNLSSEATIRSLAAGI
LPQLFPSIKIVGRNGEQDEGSLIAIETVDIINRSCPFLVRCSILPTIKAV
VMKADMKPITNEIADTGIHYELILNFEFPISSGNYLFGFDAFWNHLVADF
DSTSSSLLEANAGTDKILASIEYELKPNSNLWEKLNSWLTYSVTLFKERL
THDSNLIPQRNTVYKYKSNYLSIKNHKINKLSTTTNFRKRKEYSCSSPPN
KLYSQRKSFSPREIGKNRIKFPFESSFQSDIGFESGDNTSVVKARCRNCS
IKLEGTHFVQCPAFCEHKFCFECTRNYLRKHSSVTSTSHNSLNFEEIYCP
SSEKCILPGSSSPWSFLQTEINTILSGDNKEIKTSPKLFNVVAEVGEDLS
INKKEKINEDI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0016567protein ubiquitination
GO:1903507negative regulation of nucleic acid-templated transcription
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
Vocabulary: molecular function
TermDefinition
GO:0046872metal ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR022750Interferon_reg_fac2-bd1_2_Znf
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:1.10.10.1580coord: 408..476
e-value: 3.6E-23
score: 83.5
NoneNo IPR availablePANTHERPTHR10816:SF19coord: 329..483
NoneNo IPR availablePANTHERPTHR10816MYELIN TRANSCRIPTION FACTOR 1-RELATEDcoord: 329..483
coord: 12..100
NoneNo IPR availablePANTHERPTHR10816:SF19coord: 12..100
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 395..474
IPR022750Interferon regulatory factor 2-binding protein 1 & 2, zinc fingerPFAMPF11261IRF-2BP1_2coord: 20..69
e-value: 4.6E-31
score: 106.1