Dynein light chain

Overview


Name	Dynein light chain
Smed ID	SMED30002803
Length (bp)	806

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Dynein light chain (SMED30002803) t-SNE clustered cells

Violin plots show distribution of expression levels for Dynein light chain (SMED30002803) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dynein light chain (SMED30002803) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dynein light chain (SMED30002803) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30002803

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30002803	SMESG000043382.1	dd_Smed_v4_7954_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30002803	SMESG000043382.1	dd_Smed_v4_7954_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30002803	SMESG000043382.1	dd_Smed_v4_7954_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30002803	SMESG000043382.1	dd_Smed_v4_7954_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL2 (dynein light chain LC8-type 2 [Source:HGNC Symbol;Acc:HGNC:24596])

HSP 1 Score: 63.5438 bits (153), Expect = 1.432e-12
Identity = 29/85 (34.12%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 62.7734 bits (151), Expect = 2.509e-12
Identity = 28/85 (32.94%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  + +   QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDSVECATQAL---EKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  + +   QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDSVECATQAL---EKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  + +   QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDSVECATQAL---EKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  + +   QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDSVECATQAL---EKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-1 (Dynein light chain 1, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q22799])

HSP 1 Score: 62.003 bits (149), Expect = 1.817e-12
Identity = 28/85 (32.94%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM ++++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSDDMQQDAIDCATQAL---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM ++++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSDDMQQDAIDCATQAL---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM ++++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSDDMQQDAIDCATQAL---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-5 (Dynein Light Chain [Source:UniProtKB/TrEMBL;Acc:Q65XS9])

HSP 1 Score: 51.9878 bits (123), Expect = 5.612e-8
Identity = 21/87 (24.14%), Postives = 46/87 (52.87%), Query Frame = 2

Query:  221 EIEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGGL 481
            +++ + MP +++  A  +  +++      ++E +IA  ++   + ++ P W CI GK +G+ +T E +S +Y        +LFK  L
Sbjct:   59 DVQHSRMPRHMEQEACSLAAKSI---MTYHLEHDIARHLKMAFDREYGPDWHCICGKHFGSFVTFEPDSFIYFRIGTIAFMLFKTSL 142

[Close]

BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-2 (Probable dynein light chain 2, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q21557])

HSP 1 Score: 48.1358 bits (113), Expect = 2.335e-7
Identity = 19/88 (21.59%), Postives = 50/88 (56.82%), Query Frame = 2

Query:  215 QIEIEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            +IE+++TDM +  ++    ++ +A    +  N+++++A  ++E+++  F   W  I GK +G+ +++E    +    N   ++++K G
Sbjct:    5 KIEVKETDMEDPQRDMVISVVREA---QRLYNIDKDVAAFVKEELDKKFGATWHVICGKCFGSRVSYEMGHFILLKCNKVNVMIYKCG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Fly
Match: ctp (gene:FBgn0011760 transcript:FBtr0070706)

HSP 1 Score: 62.7734 bits (151), Expect = 1.358e-12
Identity = 29/85 (34.12%), Postives = 47/85 (55.29%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE    +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDAVDCATQAL---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Fly
Match: ctp (gene:FBgn0011760 transcript:FBtr0070704)

HSP 1 Score: 62.7734 bits (151), Expect = 1.358e-12
Identity = 29/85 (34.12%), Postives = 47/85 (55.29%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE    +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDAVDCATQAL---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Fly
Match: ctp (gene:FBgn0011760 transcript:FBtr0307065)

HSP 1 Score: 62.7734 bits (151), Expect = 1.358e-12
Identity = 29/85 (34.12%), Postives = 47/85 (55.29%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE    +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDAVDCATQAL---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Fly
Match: ctp (gene:FBgn0011760 transcript:FBtr0070707)

HSP 1 Score: 62.7734 bits (151), Expect = 1.358e-12
Identity = 29/85 (34.12%), Postives = 47/85 (55.29%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE    +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDAVDCATQAL---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Fly
Match: Cdlc2 (gene:FBgn0026141 transcript:FBtr0077924)

HSP 1 Score: 62.3882 bits (150), Expect = 1.960e-12
Identity = 29/85 (34.12%), Postives = 47/85 (55.29%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE    +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDAVDCATQAL---EKYNIEKDIAAFIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dynll2a (dynein, light chain, LC8-type 2a [Source:ZFIN;Acc:ZDB-GENE-030828-11])

HSP 1 Score: 63.5438 bits (153), Expect = 9.584e-13
Identity = 29/85 (34.12%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dynll2b (dynein, light chain, LC8-type 2b [Source:ZFIN;Acc:ZDB-GENE-050320-132])

HSP 1 Score: 63.5438 bits (153), Expect = 9.584e-13
Identity = 29/85 (34.12%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dynll1 (dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1961])

HSP 1 Score: 63.1586 bits (152), Expect = 1.175e-12
Identity = 29/85 (34.12%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  A +   QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDAVECATQAL---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  A +   QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDAVECATQAL---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Xenopus
Match: dynll2 (dynein light chain LC8-type 2 [Source:NCBI gene;Acc:100038056])

HSP 1 Score: 63.5438 bits (153), Expect = 1.298e-12
Identity = 29/85 (34.12%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Xenopus
Match: dynll1 (dynein light chain LC8-type 1 [Source:NCBI gene;Acc:448652])

HSP 1 Score: 61.6178 bits (148), Expect = 5.744e-12
Identity = 29/85 (34.12%), Postives = 47/85 (55.29%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  A     QA+      N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDAVDCATQALEKF---NIEKDIAAFIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dynll2 (dynein light chain LC8-type 2 [Source:MGI Symbol;Acc:MGI:1915347])

HSP 1 Score: 63.5438 bits (153), Expect = 9.828e-13
Identity = 29/85 (34.12%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dynll1 (dynein light chain LC8-type 1 [Source:MGI Symbol;Acc:MGI:1861457])

HSP 1 Score: 62.7734 bits (151), Expect = 1.722e-12
Identity = 28/85 (32.94%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  + +   QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDSVECATQAL---EKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  + +   QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDSVECATQAL---EKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q86A88|DYL_DICDI (Dynein light chain, cytoplasmic OS=Dictyostelium discoideum OX=44689 GN=dlcB PE=3 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 8.825e-15
Identity = 31/89 (34.83%), Postives = 55/89 (61.80%), Query Frame = 2

Query:  212 YQIEIEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            Y I ++  DMP+ ++  A +   +A    +  N+ER+IA+ I+++ +  + P W CIVGK +G+ +THE ++ +Y   N + +LLFK G
Sbjct:    6 YIINVKNADMPDFMQQDATECTIKAF---EETNIERDIAMIIKKEFDKKYSPTWHCIVGKSFGSFVTHETKNFIYFNINKHSVLLFKAG 91

[Close]

BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|O02414|DYL1_HELCR (Dynein light chain LC6, flagellar outer arm OS=Heliocidaris crassispina OX=1043166 PE=3 SV=1)

HSP 1 Score: 65.855 bits (159), Expect = 1.069e-12
Identity = 29/85 (34.12%), Postives = 50/85 (58.82%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DMPE+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       +LLFK G
Sbjct:    8 IKNADMPEDMQQDAVDCATQAL---EKFNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAVLLFKSG 89

[Close]

BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q78P75|DYL2_RAT (Dynein light chain 2, cytoplasmic OS=Rattus norvegicus OX=10116 GN=Dynll2 PE=1 SV=1)

HSP 1 Score: 63.5438 bits (153), Expect = 6.875e-12
Identity = 29/85 (34.12%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q9D0M5|DYL2_MOUSE (Dynein light chain 2, cytoplasmic OS=Mus musculus OX=10090 GN=Dynll2 PE=1 SV=1)

HSP 1 Score: 63.5438 bits (153), Expect = 6.875e-12
Identity = 29/85 (34.12%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q96FJ2|DYL2_HUMAN (Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1)

HSP 1 Score: 63.5438 bits (153), Expect = 6.875e-12
Identity = 29/85 (34.12%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. TrEMBL
Match: A0A151ZDM6 (Dynein light chain OS=Tieghemostelium lacteum OX=361077 GN=DLAC_06872 PE=3 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 8.665e-14
Identity = 32/89 (35.96%), Postives = 56/89 (62.92%), Query Frame = 2

Query:  212 YQIEIEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            Y I ++  DMP+ ++  A ++  +A    K   +ER+IA+ I+++ +  + P W CIVGK +G+ +THE +S +Y   N++ +LLFK G
Sbjct:    5 YSISVKNVDMPDFMQQDATELAIKAFEEAK---IERDIAMIIKKEFDKKYSPTWHCIVGKSFGSHVTHETKSFIYFHINNHSVLLFKTG 90

[Close]

BLAST of Dynein light chain vs. TrEMBL
Match: A0A0R3W7W0 (Dynein light chain OS=Taenia asiatica OX=60517 GN=TASK_LOCUS6396 PE=3 SV=1)

HSP 1 Score: 71.633 bits (174), Expect = 1.820e-12
Identity = 30/85 (35.29%), Postives = 52/85 (61.18%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            ++ TDMPE ++  A +  E+A   P   N+E++IA  I++  + +F P W C+VG+ +G+ +THE++  +Y       ILL+K G
Sbjct:    8 VKNTDMPEEMQQRAIECAEEA---PDRYNIEKDIAAHIKKFFDKEFSPTWHCVVGRNFGSYVTHEEKKFVYFYIGHVAILLYKSG 89

[Close]

BLAST of Dynein light chain vs. TrEMBL
Match: A0A3L6KVX7 (Dynein light chain OS=Trypanosoma brucei equiperdum OX=630700 GN=DPX39_110011400 PE=3 SV=1)

HSP 1 Score: 70.8626 bits (172), Expect = 3.933e-12
Identity = 31/85 (36.47%), Postives = 54/85 (63.53%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DMPE++++ A ++  QA+   +  N+E++IA  I+++ +  ++P W CIVG+ +G+ +THE  S +Y       ILLFK G
Sbjct:    9 IKNADMPEDMQSDAVEVALQAL---EKFNIEKDIAAYIKKEFDKKYQPTWHCIVGRNFGSYVTHETHSFLYFYFGQVAILLFKSG 90

[Close]

BLAST of Dynein light chain vs. TrEMBL
Match: A0A1G4HZW5 (Dynein light chain OS=Trypanosoma equiperdum OX=5694 GN=TEOVI_000899700 PE=3 SV=1)

HSP 1 Score: 70.8626 bits (172), Expect = 3.933e-12
Identity = 31/85 (36.47%), Postives = 54/85 (63.53%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DMPE++++ A ++  QA+   +  N+E++IA  I+++ +  ++P W CIVG+ +G+ +THE  S +Y       ILLFK G
Sbjct:    9 IKNADMPEDMQSDAVEVALQAL---EKFNIEKDIAAYIKKEFDKKYQPTWHCIVGRNFGSYVTHETHSFLYFYFGQVAILLFKSG 90

[Close]

BLAST of Dynein light chain vs. TrEMBL
Match: D0A5K4 (Dynein light chain OS=Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) OX=679716 GN=TbgDal_XI700 PE=3 SV=1)

HSP 1 Score: 70.8626 bits (172), Expect = 3.933e-12
Identity = 31/85 (36.47%), Postives = 54/85 (63.53%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DMPE++++ A ++  QA+   +  N+E++IA  I+++ +  ++P W CIVG+ +G+ +THE  S +Y       ILLFK G
Sbjct:    9 IKNADMPEDMQSDAVEVALQAL---EKFNIEKDIAAYIKKEFDKKYQPTWHCIVGRNFGSYVTHETHSFLYFYFGQVAILLFKSG 90

[Close]

BLAST of Dynein light chain vs. Ensembl Cavefish
Match: ENSAMXT00000047143.1 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:103041528])

HSP 1 Score: 63.5438 bits (153), Expect = 8.122e-13
Identity = 29/85 (34.12%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Cavefish
Match: dynll2b (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:103041528])

HSP 1 Score: 63.5438 bits (153), Expect = 8.122e-13
Identity = 29/85 (34.12%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Cavefish
Match: dynll1 (dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1961])

HSP 1 Score: 54.6842 bits (130), Expect = 2.256e-9
Identity = 27/98 (27.55%), Postives = 51/98 (52.04%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMY---ATTNDYGILL-FKGGL*LMRLMCC 505
            I+  DM E ++  A +   QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y      N + + +  + G       CC
Sbjct:    8 IKNADMSEEMQQDAVECATQAL---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQRNGWAVWVEARTGFFWTLTWCC 102

[Close]

BLAST of Dynein light chain vs. Ensembl Yeast
Match: DYN2 (Cytoplasmic light chain dynein, microtubule motor protein; required for intracellular transport and cell division; involved in mitotic spindle positioning; forms complex with dynein intermediate chain Pac11p that promotes Dyn1p homodimerization, potentiates motor processivity; Dyn2p-Pac11p complex important for interaction of dynein motor complex with dynactin complex; acts as molecular glue to dimerize, stabilize Nup82-Nsp1-Nup159 complex module of cytoplasmic pore filaments [Source:SGD;Acc:S000002832])

HSP 1 Score: 46.595 bits (109), Expect = 1.367e-7
Identity = 22/83 (26.51%), Postives = 45/83 (54.22%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFK 472
            ++ +D+ + +K     I + A+       +ER+IA  +++++++ +   W  IVGK +G+ +THEK   +Y        L+FK
Sbjct:   11 VKASDITDKLKEDILTISKDALDK---YQLERDIAGTVKKQLDVKYGNTWHVIVGKNFGSYVTHEKGHFVYFYIGPLAFLVFK 90

[Close]

BLAST of Dynein light chain vs. Ensembl Nematostella
Match: EDO44582 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVI5])

HSP 1 Score: 63.1586 bits (152), Expect = 3.906e-13
Identity = 30/85 (35.29%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A   IE A    +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMAEDMQTDA---IECATQALEKFNIEKDIAAFIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Medaka
Match: dynll1 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101171417])

HSP 1 Score: 63.929 bits (154), Expect = 5.257e-13
Identity = 29/85 (34.12%), Postives = 50/85 (58.82%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A +   QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEDMQQDAVECATQAL---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Medaka
Match: ENSORLT00000005747.2 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101162462])

HSP 1 Score: 62.7734 bits (151), Expect = 1.734e-12
Identity = 29/85 (34.12%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E ++  A     QA+   +  N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSEEMQQDAVDCATQAM---EKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Ensembl Medaka
Match: DYNLL2 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101174042])

HSP 1 Score: 60.4622 bits (145), Expect = 1.059e-11
Identity = 27/85 (31.76%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM + ++  A     QA+   +  N+E++IA  ++++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    8 IKNADMSDEMQQDAVDCAMQAM---EKYNIEKDIAAYVKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000043382.1 (SMESG000043382.1)

HSP 1 Score: 192.2 bits (487), Expect = 1.161e-62
Identity = 92/92 (100.00%), Postives = 92/92 (100.00%), Query Frame = 2

Query:  206 MIYQIEIEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGGL 481
            MIYQIEIEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGGL
Sbjct:    1 MIYQIEIEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGGL 92

[Close]

BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000003270.1 (SMESG000003270.1)

HSP 1 Score: 84.3445 bits (207), Expect = 1.180e-20
Identity = 36/91 (39.56%), Postives = 59/91 (64.84%), Query Frame = 2

Query:  206 MIYQIEIEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            M + ++  +TDM ++++  A + I  A  N  N   E+NI  EIR+K +    PQW CI+GKK+G+S++HEK +L+Y    D+G++L+K G
Sbjct:    1 MEFIVDESKTDMTDSMRIEALEAIRSAFYNEDNNGQEKNICAEIRKKFDALHFPQWHCIMGKKFGSSVSHEKGTLLYGACGDHGLMLWKAG 91

[Close]

BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000019341.1 (SMESG000019341.1)

HSP 1 Score: 78.1814 bits (191), Expect = 1.898e-18
Identity = 39/91 (42.86%), Postives = 62/91 (68.13%), Query Frame = 2

Query:  206 MIYQIEIEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            M + ++  +TDM   ++  A   I +A+ N +N N E+NI  +IR+K +    PQW C++GKK+G+S+THEK +L+Y TT DYG++L+K G
Sbjct:    1 MEFNVDDSKTDMGNQMREEAINTIMEALQNEENNNQEKNICAQIRKKFDELHYPQWHCVMGKKFGSSVTHEKGTLIYGTTGDYGLMLWKAG 91

[Close]

BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000005286.1 (SMESG000005286.1)

HSP 1 Score: 64.3142 bits (155), Expect = 2.607e-13
Identity = 31/88 (35.23%), Postives = 50/88 (56.82%), Query Frame = 2

Query:  215 QIEIEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            Q  I+  DM + ++ AA     QA+   +  N+E++IA  I+++ +  F P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:    5 QAVIKNADMTDEMQEAAINYATQAM---EKFNIEKDIAAYIKKEFDKSFNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 89

[Close]

BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000043518.1 (SMESG000043518.1)

HSP 1 Score: 62.7734 bits (151), Expect = 1.013e-12
Identity = 29/85 (34.12%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  224 IEQTDMPENVKNAAAKIIEQAVSNPKNQNVERNIALEIREKMNLDFKPQWQCIVGKKYGTSITHEKESLMYATTNDYGILLFKGG 478
            I+  DM E+++  A +   QA+      N+E++IA  I+++ +  + P W CIVG+ +G+ +THE +  +Y       ILLFK G
Sbjct:   10 IKNADMSEDMQQDAVECATQAMEKF---NIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG 91

The following BLAST results are available for this feature:

BLAST of Dynein light chain vs. Ensembl Human
BLAST of Dynein light chain vs. Ensembl Celegans
BLAST of Dynein light chain vs. Ensembl Fly
BLAST of Dynein light chain vs. Ensembl Zebrafish
BLAST of Dynein light chain vs. Ensembl Xenopus
BLAST of Dynein light chain vs. Ensembl Mouse
BLAST of Dynein light chain vs. UniProt/SwissProt
BLAST of Dynein light chain vs. TrEMBL
BLAST of Dynein light chain vs. Ensembl Cavefish
BLAST of Dynein light chain vs. Ensembl Sea Lamprey
BLAST of Dynein light chain vs. Ensembl Yeast
BLAST of Dynein light chain vs. Ensembl Nematostella
BLAST of Dynein light chain vs. Ensembl Medaka
BLAST of Dynein light chain vs. Planmine SMEST

BLAST of Dynein light chain vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DYNLL2	1.432e-12	34.12	dynein light chain LC8-type 2 [Source:HGNC Symbol;...	[more]
DYNLL1	2.509e-12	32.94	dynein light chain LC8-type 1 [Source:HGNC Symbol;...	[more]
DYNLL1	2.509e-12	32.94	dynein light chain LC8-type 1 [Source:HGNC Symbol;...	[more]
DYNLL1	2.509e-12	32.94	dynein light chain LC8-type 1 [Source:HGNC Symbol;...	[more]
DYNLL1	2.509e-12	32.94	dynein light chain LC8-type 1 [Source:HGNC Symbol;...	[more]

BLAST of Dynein light chain vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dlc-1	1.817e-12	32.94	Dynein light chain 1, cytoplasmic [Source:UniProt...	[more]
dlc-1	1.817e-12	32.94	Dynein light chain 1, cytoplasmic [Source:UniProt...	[more]
dlc-1	1.817e-12	32.94	Dynein light chain 1, cytoplasmic [Source:UniProt...	[more]
dlc-5	5.612e-8	24.14	Dynein Light Chain [Source:UniProtKB/TrEMBL;Acc:Q...	[more]
dlc-2	2.335e-7	21.59	Probable dynein light chain 2, cytoplasmic [Sourc...	[more]

BLAST of Dynein light chain vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ctp	1.358e-12	34.12	gene:FBgn0011760 transcript:FBtr0070706	[more]
ctp	1.358e-12	34.12	gene:FBgn0011760 transcript:FBtr0070704	[more]
ctp	1.358e-12	34.12	gene:FBgn0011760 transcript:FBtr0307065	[more]
ctp	1.358e-12	34.12	gene:FBgn0011760 transcript:FBtr0070707	[more]
Cdlc2	1.960e-12	34.12	gene:FBgn0026141 transcript:FBtr0077924	[more]

BLAST of Dynein light chain vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dynll2a	9.584e-13	34.12	dynein, light chain, LC8-type 2a [Source:ZFIN;Acc:...	[more]
dynll2b	9.584e-13	34.12	dynein, light chain, LC8-type 2b [Source:ZFIN;Acc:...	[more]
dynll2a	9.584e-13	34.12	dynein, light chain, LC8-type 2a [Source:ZFIN;Acc:...	[more]
dynll1	1.175e-12	34.12	dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:Z...	[more]
dynll1	1.175e-12	34.12	dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:Z...	[more]

BLAST of Dynein light chain vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2


Match Name	E-value	Identity	Description
dynll2	1.298e-12	34.12	dynein light chain LC8-type 2 [Source:NCBI gene;Ac...	[more]
dynll1	5.744e-12	34.12	dynein light chain LC8-type 1 [Source:NCBI gene;Ac...	[more]

BLAST of Dynein light chain vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Dynll2	9.828e-13	34.12	dynein light chain LC8-type 2 [Source:MGI Symbol;A...	[more]
Dynll2	9.828e-13	34.12	dynein light chain LC8-type 2 [Source:MGI Symbol;A...	[more]
Dynll2	9.828e-13	34.12	dynein light chain LC8-type 2 [Source:MGI Symbol;A...	[more]
Dynll1	1.722e-12	32.94	dynein light chain LC8-type 1 [Source:MGI Symbol;A...	[more]
Dynll1	1.722e-12	32.94	dynein light chain LC8-type 1 [Source:MGI Symbol;A...	[more]

BLAST of Dynein light chain vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q86A88\|DYL_DICDI	8.825e-15	34.83	Dynein light chain, cytoplasmic OS=Dictyostelium d...	[more]
sp\|O02414\|DYL1_HELCR	1.069e-12	34.12	Dynein light chain LC6, flagellar outer arm OS=Hel...	[more]
sp\|Q78P75\|DYL2_RAT	6.875e-12	34.12	Dynein light chain 2, cytoplasmic OS=Rattus norveg...	[more]
sp\|Q9D0M5\|DYL2_MOUSE	6.875e-12	34.12	Dynein light chain 2, cytoplasmic OS=Mus musculus ...	[more]
sp\|Q96FJ2\|DYL2_HUMAN	6.875e-12	34.12	Dynein light chain 2, cytoplasmic OS=Homo sapiens ...	[more]

BLAST of Dynein light chain vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A151ZDM6	8.665e-14	35.96	Dynein light chain OS=Tieghemostelium lacteum OX=3...	[more]
A0A0R3W7W0	1.820e-12	35.29	Dynein light chain OS=Taenia asiatica OX=60517 GN=...	[more]
A0A3L6KVX7	3.933e-12	36.47	Dynein light chain OS=Trypanosoma brucei equiperdu...	[more]
A0A1G4HZW5	3.933e-12	36.47	Dynein light chain OS=Trypanosoma equiperdum OX=56...	[more]
D0A5K4	3.933e-12	36.47	Dynein light chain OS=Trypanosoma brucei gambiense...	[more]

BLAST of Dynein light chain vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ENSAMXT00000047143.1	8.122e-13	34.12	dynein light chain 2, cytoplasmic [Source:NCBI gen...	[more]
dynll2b	8.122e-13	34.12	dynein light chain 2, cytoplasmic [Source:NCBI gen...	[more]
dynll1	2.256e-9	27.55	dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:Z...	[more]

BLAST of Dynein light chain vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Dynein light chain vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
DYN2	1.367e-7	26.51	Cytoplasmic light chain dynein, microtubule motor ...	[more]

BLAST of Dynein light chain vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO44582	3.906e-13	35.29	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Dynein light chain vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
dynll1	5.257e-13	34.12	dynein light chain 2, cytoplasmic [Source:NCBI gen...	[more]
ENSORLT00000005747.2	1.734e-12	34.12	dynein light chain 2, cytoplasmic [Source:NCBI gen...	[more]
DYNLL2	1.059e-11	31.76	dynein light chain 2, cytoplasmic [Source:NCBI gen...	[more]

BLAST of Dynein light chain vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000043382.1	1.161e-62	100.00	SMESG000043382.1	[more]
SMESG000003270.1	1.180e-20	39.56	SMESG000003270.1	[more]
SMESG000019341.1	1.898e-18	42.86	SMESG000019341.1	[more]
SMESG000005286.1	2.607e-13	35.23	SMESG000005286.1	[more]
SMESG000043518.1	1.013e-12	34.12	SMESG000043518.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence

transcript sequence

>SMED30002803 ID=SMED30002803|Name=Dynein light chain|organism=Schmidtea mediterranea sexual|type=transcript|length=806bp
CACATCATTGTTACTAATAGATTCAAATTGCAGATAAATTCAACTTCTGC
TTGTGTGCTGAATAGTTTTCTAAAAATAATAAATATAAATCTAGAAAAAG
AAAAACCGAAAAATTTTTTTTTAGATATTTTCATTGTCCGTAAAAAAATT
TTTTTTCTGATTTCTTATTGATTATTTTTCTCTTTTGTTATTTTTCAACT
TGAAAATGATTTATCAAATTGAAATCGAACAAACGGACATGCCGGAAAAT
GTGAAAAACGCAGCAGCAAAAATCATCGAACAAGCCGTATCGAATCCGAA
AAATCAAAACGTAGAACGCAATATTGCTTTGGAAATACGTGAAAAGATGA
ATTTGGATTTTAAGCCCCAATGGCAGTGCATAGTGGGCAAAAAATATGGG
ACGAGTATTACCCATGAAAAGGAGTCACTAATGTACGCCACGACGAACGA
CTATGGGATATTACTATTCAAAGGAGGTCTGTAATTGATGAGATTAATGT
GCTGTAGCAATATCAGCACTTCCTTTTGTTGATTGATATCAATTGTTTAA
ATGAGCTCTGCTAGAGTAAATACATTTTCTGCAATTAGAGTTTTATGATG
AATGCTAATTCATTTTTCTATTAGCAAATAGCACTTTGTATTGATTTTAG
TCACTGTAAATATCAATATTTGTCGTTATATATATATTTAAACCGTGATA
TGAATTTTTAGTTTGAATTTTGTATTCCTATGACTTGAAAGGAAATTTAC
ACAGTTGAAAATGTAGTGTAAAGTTTTAAGGTAGACTTTTGTTTAAATGA
ATTTTA

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000034	epidermis
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR037177	DLC_sf
IPR001372	Dynein_light_chain_typ-1/2

Vocabulary: **biological process**
Term	Definition
GO:0007017	microtubule-based process

Vocabulary: **cellular component**
Term	Definition
GO:0030286	dynein complex
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005874	microtubule
GO:0005875	microtubule associated complex

Vocabulary: **molecular function**
Term	Definition
GO:0003774	motor activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001372	Dynein light chain, type 1/2	SMART	SM01375	Dynein_light_2	coord: 1..90 e-value: 7.1E-19 score: 78.7
IPR001372	Dynein light chain, type 1/2	PFAM	PF01221	Dynein_light	coord: 5..89 e-value: 4.0E-22 score: 78.3
IPR001372	Dynein light chain, type 1/2	PANTHER	PTHR11886	DYNEIN LIGHT CHAIN	coord: 4..89
IPR037177	Dynein light chain superfamily	GENE3D	G3DSA:3.30.740.10		coord: 3..91 e-value: 1.4E-21 score: 78.3
IPR037177	Dynein light chain superfamily	SUPERFAMILY	SSF54648	DLC	coord: 4..91
None	No IPR available	PANTHER	PTHR11886:SF35	DYNEIN LIGHT CHAIN 2, CYTOPLASMIC	coord: 4..89

Main menu

Dynein light chain

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

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