insulin gene enhancer protein isl-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002801 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Human
Match: ISL1 (ISL LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6132]) HSP 1 Score: 164.466 bits (415), Expect = 2.730e-45 Identity = 75/134 (55.97%), Postives = 94/134 (70.15%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
D G KR I SLCVGCG I D++ILRV PDLEWHA CL+C +CN+ LDE TCFV+DGKTYCK DY +L+ CA C+ G K+D+V+ S++YHI C +CVAC+R L GDEFA+R +G+ C DH
Sbjct: 3 DMGDPPKKKRLI---SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133 HSP 2 Score: 149.058 bits (375), Expect = 1.153e-39 Identity = 82/142 (57.75%), Postives = 94/142 (66.20%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR IM+KQ+ Q Q P ANP+E+Q PW + +F+ +S+ PAFQQL++
Sbjct: 179 EKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQ-----------------------PNDKTANPVEVQSYQPPW---KVLSDFA----LQSDIDQPAFQQLVN 290
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Human
Match: ISL2 (ISL LIM homeobox 2 [Source:HGNC Symbol;Acc:HGNC:18524]) HSP 1 Score: 165.622 bits (418), Expect = 2.816e-45 Identity = 88/146 (60.27%), Postives = 105/146 (71.92%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGS-EEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+ I++KQ+ Q Q L G P+VAGSP+R+E + + +E+Q PW + EF +S+ PAFQQL+S
Sbjct: 187 QTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQ-GSAVEVQTYQPPWKALSEFA--------LQSDLDQPAFQQLVS 323 HSP 2 Score: 152.91 bits (385), Expect = 1.110e-40 Identity = 76/182 (41.76%), Postives = 104/182 (57.14%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSASILTRTE---------RLPQSHQPASPLKQPKQELETESLMKIEDETNSRK 694
++CVGCG I D+FILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +LF CA C G SD V+ +YHI C +C C+R L GDEF++R + ++C DH L LE +A+ R+ LP + P +P +TE ++ N ++
Sbjct: 25 AMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHG----LLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQ 202
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Human
Match: ISL1 (ISL LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6132]) HSP 1 Score: 165.236 bits (417), Expect = 2.889e-45 Identity = 89/145 (61.38%), Postives = 107/145 (73.79%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR IM+KQ+ Q Q + + G PMVA SP R++ + ANP+E+Q PW + +F+ +S+ PAFQQL++
Sbjct: 177 QPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQ-ANPVEVQSYQPPW---KVLSDFA----LQSDIDQPAFQQLVN 313 HSP 2 Score: 164.851 bits (416), Expect = 3.505e-45 Identity = 75/134 (55.97%), Postives = 94/134 (70.15%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
D G KR I SLCVGCG I D++ILRV PDLEWHA CL+C +CN+ LDE TCFV+DGKTYCK DY +L+ CA C+ G K+D+V+ S++YHI C +CVAC+R L GDEFA+R +G+ C DH
Sbjct: 3 DMGDPPKKKRLI---SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Human
Match: LHX9 (LIM homeobox 9 [Source:HGNC Symbol;Acc:HGNC:14222]) HSP 1 Score: 122.865 bits (307), Expect = 7.456e-30 Identity = 53/116 (45.69%), Postives = 74/116 (63.79%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLF-LQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVIC 520
+LC GCGG I+D++ L + D +WH RCL+C +C L+ + TCF KDG YCKEDY + F +Q CA C+ G+ S+ V+ +YH+SC C CN+ L TGD F M+ + V C
Sbjct: 60 ALCAGCGGKISDRYYL-LAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYC 174 HSP 2 Score: 63.1586 bits (152), Expect = 4.957e-10 Identity = 32/78 (41.03%), Postives = 47/78 (60.26%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGID 1243
QKT R+RT QL T+++ +A N PDA +QL + TGL+ RV++VWFQN R K ++ + Q+ GG+D
Sbjct: 256 QKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLL-------RQENGGVD 326
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Human
Match: LHX9 (LIM homeobox 9 [Source:HGNC Symbol;Acc:HGNC:14222]) HSP 1 Score: 122.479 bits (306), Expect = 1.237e-29 Identity = 53/116 (45.69%), Postives = 74/116 (63.79%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLF-LQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVIC 520
+LC GCGG I+D++ L + D +WH RCL+C +C L+ + TCF KDG YCKEDY + F +Q CA C+ G+ S+ V+ +YH+SC C CN+ L TGD F M+ + V C
Sbjct: 69 ALCAGCGGKISDRYYL-LAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYC 183 HSP 2 Score: 63.1586 bits (152), Expect = 6.475e-10 Identity = 32/78 (41.03%), Postives = 47/78 (60.26%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGID 1243
QKT R+RT QL T+++ +A N PDA +QL + TGL+ RV++VWFQN R K ++ + Q+ GG+D
Sbjct: 265 QKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLL-------RQENGGVD 335
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Celegans
Match: lim-7 (CeLIM-7; LIM domain family [Source:UniProtKB/TrEMBL;Acc:G5EC36]) HSP 1 Score: 134.035 bits (336), Expect = 1.037e-33 Identity = 55/119 (46.22%), Postives = 86/119 (72.27%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSR-IYHISCMKCVACNRVLQTGDEFAMRPNGVICLHD 529
++C GC I+D++ LRV P+LE+HA+CL+CV+C+R LDE T FVK+G+TYC++DY++LF C+ C+ K+D V+ G + ++H++C CVAC + LQTG+EF ++ N + C D
Sbjct: 54 AVCAGCRLEISDRYFLRVNPNLEFHAQCLKCVQCSRPLDENQTAFVKNGQTYCRDDYRRLFTTRCSRCHGDFDKTDLVMRAGPQNVFHLNCFACVACEKRLQTGEEFQIKNNSLYCRSD 172 HSP 2 Score: 110.538 bits (275), Expect = 1.141e-25 Identity = 51/72 (70.83%), Postives = 60/72 (83.33%), Query Frame = 2
Query: 995 KRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQ 1210
K+ K+++ TRVRTVLNE QL LR CY+ N RPDA +KE+LVEMTGLS RVIRVWFQNKRCKDKKRQI + +
Sbjct: 258 KKKKDKQATRVRTVLNENQLKILRDCYSINSRPDATLKERLVEMTGLSARVIRVWFQNKRCKDKKRQIQITE 329
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Celegans
Match: lin-11 (pep chromosome:WBcel235:I:10248256:10255327:1 gene:WBGene00003000.1 transcript:ZC247.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-11) HSP 1 Score: 91.2781 bits (225), Expect = 1.565e-19 Identity = 43/119 (36.13%), Postives = 60/119 (50.42%), Query Frame = 2
Query: 182 CVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDE-FAMRPNGVICLHDHQ 535
C C I D+++ V WH CLRC C + TCF +DG CK D+ + + Q CA C+ L K D V +++HI C +C C R+L TGD+ + M N +C D Q
Sbjct: 68 CAACAQPILDRYVFTVLGKC-WHQSCLRCCDCRAPM--SMTCFSRDGLILCKTDFSRRYSQRCAGCDGKLEKEDLVRRARDKVFHIRCFQCSVCQRLLDTGDQLYIMEGNRFVCQSDFQ 183 HSP 2 Score: 62.3882 bits (150), Expect = 3.433e-10 Identity = 27/54 (50.00%), Postives = 39/54 (72.22%), Query Frame = 2
Query: 1028 RTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 1189
RT + KQL TL+ +AA P+P ++EQL TGL+ RVI+VWFQN+R K+++
Sbjct: 245 RTTIKAKQLETLKNAFAATPKPTRHIREQLAAETGLNMRVIQVWFQNRRSKERR 298
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Celegans
Match: lim-6 (LIM domain family [Source:UniProtKB/TrEMBL;Acc:G4RV72]) HSP 1 Score: 88.9669 bits (219), Expect = 3.342e-19 Identity = 45/119 (37.82%), Postives = 59/119 (49.58%), Query Frame = 2
Query: 179 LCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQ 535
LC GCG I D++I RV D +H CLRC C L CF + G YC+ D+Q L+ + C C L +D V V YH C C +C R GDE+ + V C +D+Q
Sbjct: 41 LCSGCGCLIKDRYIYRVMED-SYHESCLRCSCCQLSLSSFKKCFSRHGNIYCEHDHQMLYGKRCRRCMTLLLPTDIVHRVHFMYYHAQCFSCCSCQRPFNLGDEYHVFDGEVFCRNDYQ 158 HSP 2 Score: 56.9954 bits (136), Expect = 1.602e-8 Identity = 26/56 (46.43%), Postives = 37/56 (66.07%), Query Frame = 2
Query: 1022 RVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 1189
R RT+LN +Q +T + + +P ++EQL TGLS RV++VWFQN+R K KK
Sbjct: 188 RPRTILNAQQRRQFKTAFERSSKPSRKVREQLANETGLSVRVVQVWFQNQRAKIKK 243
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Celegans
Match: lim-6 (LIM domain family [Source:UniProtKB/TrEMBL;Acc:G4RV72]) HSP 1 Score: 88.1965 bits (217), Expect = 6.356e-19 Identity = 45/119 (37.82%), Postives = 59/119 (49.58%), Query Frame = 2
Query: 179 LCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQ 535
LC GCG I D++I RV D +H CLRC C L CF + G YC+ D+Q L+ + C C L +D V V YH C C +C R GDE+ + V C +D+Q
Sbjct: 41 LCSGCGCLIKDRYIYRVMED-SYHESCLRCSCCQLSLSSFKKCFSRHGNIYCEHDHQMLYGKRCRRCMTLLLPTDIVHRVHFMYYHAQCFSCCSCQRPFNLGDEYHVFDGEVFCRNDYQ 158 HSP 2 Score: 56.225 bits (134), Expect = 2.295e-8 Identity = 26/56 (46.43%), Postives = 37/56 (66.07%), Query Frame = 2
Query: 1022 RVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 1189
R RT+LN +Q +T + + +P ++EQL TGLS RV++VWFQN+R K KK
Sbjct: 188 RPRTILNAQQRRQFKTAFERSSKPSRKVREQLANETGLSVRVVQVWFQNQRAKIKK 243
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Celegans
Match: lim-4 (LIM domain family [Source:UniProtKB/TrEMBL;Acc:A0A1X7RC92]) HSP 1 Score: 83.9593 bits (206), Expect = 2.145e-17 Identity = 40/114 (35.09%), Postives = 60/114 (52.63%), Query Frame = 2
Query: 179 LCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVIC 520
+C C I DKF L + +H CL+C C L N CF KD YCK Y + CA+C+R + +D+V + +YH++C C C R L TG+E+A++ ++C
Sbjct: 97 ICTQCQHQIQDKFFLSID-GRNYHENCLQCSTCENPL--SNKCFYKDKTFYCKGCYFRELGPKCASCDRTIQATDWVRRARNYVYHLACFSCNQCKRQLSTGEEYALQEGNLLC 207 HSP 2 Score: 63.1586 bits (152), Expect = 1.579e-10 Identity = 30/63 (47.62%), Postives = 39/63 (61.90%), Query Frame = 2
Query: 1001 SKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 1189
S++ KT RVRT E QL L+T + + PD E++ MTGLS RV +VWFQN R + KK
Sbjct: 223 SQKAKTKRVRTTFAEDQLSVLQTYFNRDSNPDGADLEKIASMTGLSKRVTQVWFQNSRARQKK 285
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Fly
Match: tup (gene:FBgn0003896 transcript:FBtr0081112) HSP 1 Score: 159.458 bits (402), Expect = 1.590e-42 Identity = 87/156 (55.77%), Postives = 109/156 (69.87%), Query Frame = 2
Query: 1013 KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVK-QMDQHQQVGGIDC-PLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFS-HGDISRS---NDSAPAFQQLISAYHHLSRNG 1462
K TRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMT LSPRVIRVWFQNKRCKDKK+ I +K QM Q ++ + +QG+PM+A SP+R++ P++ L++Q PW + +F+ H D+ + N PAFQQL++ H NG
Sbjct: 240 KPTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEKEGRKLGYGAMQGIPMIASSPVRHDSPLNLQG-LDVQTYQPPWKALS---DFALHADLDSNGAINTHTPAFQQLVNQMHGYDLNG 391 HSP 2 Score: 147.517 bits (371), Expect = 3.238e-38 Identity = 66/120 (55.00%), Postives = 82/120 (68.33%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVI-CLHDH 532
S CVGCGG I D++ILRV PDLEWHA CL+C +C + LDE TCFV+DGKTYCK DY +LF C C K+D+V+ ++I+HI C +C AC R L GDEFA+R G + C DH
Sbjct: 52 SHCVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRLFGTKCDKCGNSFSKNDFVMRAKTKIFHIECFRCSACARQLLPGDEFALRDAGALYCKEDH 171
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Fly
Match: tup (gene:FBgn0003896 transcript:FBtr0081111) HSP 1 Score: 159.844 bits (403), Expect = 3.636e-42 Identity = 87/156 (55.77%), Postives = 109/156 (69.87%), Query Frame = 2
Query: 1013 KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVK-QMDQHQQVGGIDC-PLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFS-HGDISRS---NDSAPAFQQLISAYHHLSRNG 1462
K TRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMT LSPRVIRVWFQNKRCKDKK+ I +K QM Q ++ + +QG+PM+A SP+R++ P++ L++Q PW + +F+ H D+ + N PAFQQL++ H NG
Sbjct: 240 KPTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEKEGRKLGYGAMQGIPMIASSPVRHDSPLNLQG-LDVQTYQPPWKALS---DFALHADLDSNGAINTHTPAFQQLVNQMHGYDLNG 391 HSP 2 Score: 148.288 bits (373), Expect = 4.785e-38 Identity = 66/120 (55.00%), Postives = 82/120 (68.33%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVI-CLHDH 532
S CVGCGG I D++ILRV PDLEWHA CL+C +C + LDE TCFV+DGKTYCK DY +LF C C K+D+V+ ++I+HI C +C AC R L GDEFA+R G + C DH
Sbjct: 52 SHCVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRLFGTKCDKCGNSFSKNDFVMRAKTKIFHIECFRCSACARQLLPGDEFALRDAGALYCKEDH 171
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Fly
Match: tup (gene:FBgn0003896 transcript:FBtr0342921) HSP 1 Score: 159.844 bits (403), Expect = 3.636e-42 Identity = 87/156 (55.77%), Postives = 109/156 (69.87%), Query Frame = 2
Query: 1013 KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVK-QMDQHQQVGGIDC-PLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFS-HGDISRS---NDSAPAFQQLISAYHHLSRNG 1462
K TRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMT LSPRVIRVWFQNKRCKDKK+ I +K QM Q ++ + +QG+PM+A SP+R++ P++ L++Q PW + +F+ H D+ + N PAFQQL++ H NG
Sbjct: 240 KPTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEKEGRKLGYGAMQGIPMIASSPVRHDSPLNLQG-LDVQTYQPPWKALS---DFALHADLDSNGAINTHTPAFQQLVNQMHGYDLNG 391 HSP 2 Score: 148.288 bits (373), Expect = 4.785e-38 Identity = 66/120 (55.00%), Postives = 82/120 (68.33%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVI-CLHDH 532
S CVGCGG I D++ILRV PDLEWHA CL+C +C + LDE TCFV+DGKTYCK DY +LF C C K+D+V+ ++I+HI C +C AC R L GDEFA+R G + C DH
Sbjct: 52 SHCVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRLFGTKCDKCGNSFSKNDFVMRAKTKIFHIECFRCSACARQLLPGDEFALRDAGALYCKEDH 171
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Fly
Match: Awh (gene:FBgn0013751 transcript:FBtr0330071) HSP 1 Score: 104.375 bits (259), Expect = 1.221e-24 Identity = 46/113 (40.71%), Postives = 66/113 (58.41%), Query Frame = 2
Query: 182 CVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVIC 520
C CG I+D+F L V WHA CLRC C LD + +CF+++ + YCK DY K F C+ C RG+ SD+V ++H++C C C R L TG++FA+ + V+C
Sbjct: 8 CAACGEPISDRFFLEV-GGCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKADYSKNFGAKCSKCCRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLC 119 HSP 2 Score: 58.9214 bits (141), Expect = 3.377e-9 Identity = 28/66 (42.42%), Postives = 39/66 (59.09%), Query Frame = 2
Query: 1013 KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQ 1210
KT RVRT E+QL L+ + + PD E++ +TGLS RV +VWFQN R + KK V++
Sbjct: 147 KTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIASVTGLSKRVTQVWFQNSRARQKKHIHAVRE 212
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Fly
Match: Awh (gene:FBgn0013751 transcript:FBtr0330070) HSP 1 Score: 104.76 bits (260), Expect = 1.259e-24 Identity = 46/113 (40.71%), Postives = 66/113 (58.41%), Query Frame = 2
Query: 182 CVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVIC 520
C CG I+D+F L V WHA CLRC C LD + +CF+++ + YCK DY K F C+ C RG+ SD+V ++H++C C C R L TG++FA+ + V+C
Sbjct: 8 CAACGEPISDRFFLEV-GGCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKADYSKNFGAKCSKCCRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLC 119 HSP 2 Score: 58.151 bits (139), Expect = 5.354e-9 Identity = 27/59 (45.76%), Postives = 36/59 (61.02%), Query Frame = 2
Query: 1013 KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 1189
KT RVRT E+QL L+ + + PD E++ +TGLS RV +VWFQN R + KK
Sbjct: 147 KTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIASVTGLSKRVTQVWFQNSRARQKK 205
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Zebrafish
Match: isl1 (ISL LIM homeobox 1 [Source:NCBI gene;Acc:30147]) HSP 1 Score: 166.777 bits (421), Expect = 4.507e-46 Identity = 76/134 (56.72%), Postives = 94/134 (70.15%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
D G KR I SLCVGCG I D++ILRV PDLEWHA CL+C +CN+ LDE TCFV+DGKTYCK DY +L+ CA CN G K+D+V+ S++YHI C +CVAC+R L GDEFA+R +G+ C DH
Sbjct: 3 DMGDPPKKKRLI---SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCNIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133 HSP 2 Score: 157.147 bits (396), Expect = 1.673e-42 Identity = 86/145 (59.31%), Postives = 105/145 (72.41%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR I++KQ+ Q Q + + G PMVA SP R++ + AN +E+Q PW + +F+ +S+ PAFQQL++
Sbjct: 177 QPEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSILMKQLQQQQPNDKTNIQGMTGTPMVATSPERHDGGLQ-ANQVEVQSYQPPW---KVLSDFA----LQSDIDQPAFQQLVN 313
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Zebrafish
Match: isl2a (ISL LIM homeobox 2a [Source:NCBI gene;Acc:30157]) HSP 1 Score: 167.162 bits (422), Expect = 4.821e-46 Identity = 88/146 (60.27%), Postives = 106/146 (72.60%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGS-EEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+ I++KQ+ Q Q + L G P+VAGSP+R++ + NP+E+Q PW + EF +S+ PAFQQL+S
Sbjct: 187 QSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHNDKTNLQGLTGTPLVAGSPIRHDTTVQ-GNPVEVQTYQPPWKALSEFA--------LQSDLDQPAFQQLVS 323 HSP 2 Score: 148.288 bits (373), Expect = 2.991e-39 Identity = 68/134 (50.75%), Postives = 87/134 (64.93%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
D G S K I ++CVGCG I D++ILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +LF CA CN G SD V+ +YH+ C +C C+R L GDEF++R ++C DH
Sbjct: 13 DMGDHSKKKSGI---AMCVGCGSQIHDQYILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCNIGFCSSDLVMRARDNVYHMECFRCSVCSRHLLPGDEFSLRDEELLCRADH 143
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Zebrafish
Match: isl2b (ISL LIM homeobox 2b [Source:NCBI gene;Acc:30151]) HSP 1 Score: 162.925 bits (411), Expect = 1.553e-44 Identity = 89/148 (60.14%), Postives = 107/148 (72.30%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGV---PMVAGSPMRNEPPISCANPLEIQQIPGPWGS-EEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR I++KQ+ QQ G LQG+ +VAGSP+R+ P + +P+++Q PW + EF +S+ PAFQQL+S
Sbjct: 187 QSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSILMKQL---QQQHGDKTNLQGMTGTALVAGSPIRHNPSVP-GHPVDVQAYQPPWKALSEFA--------LQSDLDQPAFQQLVS 322 HSP 2 Score: 152.91 bits (385), Expect = 6.308e-41 Identity = 71/147 (48.30%), Postives = 93/147 (63.27%), Query Frame = 2
Query: 92 IKIMTASLELEDCDDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
+ I+ +S L+D D + S ++CVGCG I D++ILRV PDLEWHA CL+CV+CN+ LDE TCFV+DGKTYCK DY +LF CA C G SD V+ +YHI C +C C+R L GDEF++R ++C DH
Sbjct: 2 VDIIFSSSFLDDMGDHSKKKS-----GLAMCVGCGSQIHDQYILRVSPDLEWHAACLKCVECNQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCTLGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSVRDEELLCRADH 143
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Zebrafish
Match: isl1l (islet1, like [Source:ZFIN;Acc:ZDB-GENE-040624-1]) HSP 1 Score: 145.206 bits (365), Expect = 1.892e-38 Identity = 58/121 (47.93%), Postives = 82/121 (67.77%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQR 538
S CVGCG I D+FILRV PDLEWHARCL+C +C++ LDE TCF++DGKT+C+E Y +L CA C++ ++V+H IYH+ C +C +CNR L GDE+ ++ ++C H +
Sbjct: 17 SFCVGCGLEILDRFILRVSPDLEWHARCLKCAECHQFLDESCTCFIRDGKTFCREHYSRLSSSKCAKCDKAFISKEFVMHSQVNIYHVQCFRCESCNRPLLPGDEYVLQDGQLLCTDHHNK 137 HSP 2 Score: 115.161 bits (287), Expect = 7.309e-28 Identity = 55/77 (71.43%), Postives = 64/77 (83.12%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMV----KQMDQH 1222
+ ++ TRVRTVL+E QL L+TCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR + + KQ++ H
Sbjct: 168 RSERATRVRTVLSETQLCMLQTCYTANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSLTMRHTQKQLEGH 244
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Zebrafish
Match: isl1l (islet1, like [Source:ZFIN;Acc:ZDB-GENE-040624-1]) HSP 1 Score: 142.51 bits (358), Expect = 1.498e-37 Identity = 59/127 (46.46%), Postives = 82/127 (64.57%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFL 556
S CVGCG I D+FILRV PDLEWHARCL+C +C++ LDE TCF++DGKT+C+E Y +L CA C++ ++V+ IYHI C +C CNR L GDE+ ++ ++C H + F+
Sbjct: 17 SFCVGCGLEILDRFILRVSPDLEWHARCLKCAECHQFLDESCTCFIRDGKTFCREHYSRLSTSKCAKCDKAFISKEFVMRSQVNIYHIQCFRCEGCNRPLLPGDEYVLQDGQLLCTDHHNKLMSAFI 143 HSP 2 Score: 114.775 bits (286), Expect = 1.217e-27 Identity = 55/75 (73.33%), Postives = 63/75 (84.00%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMV----KQMDQH 1222
++ TRVRTVL+E QL L+TCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR + + KQ++ H
Sbjct: 170 ERATRVRTVLSETQLCMLQTCYTANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSLTMRHTQKQLEGH 244
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Xenopus
Match: ISL1 (ISL LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6132]) HSP 1 Score: 164.851 bits (416), Expect = 3.447e-45 Identity = 75/134 (55.97%), Postives = 94/134 (70.15%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
D G KR I SLCVGCG I D++ILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +L+ CA CN G K+D+V+ S++YHI C +CVAC+R L GDEFA+R +G+ C DH
Sbjct: 3 DMGDPPKKKRLI---SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYIRLYGIKCAKCNIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133 HSP 2 Score: 163.31 bits (412), Expect = 1.180e-44 Identity = 88/145 (60.69%), Postives = 107/145 (73.79%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR I++KQ+ Q Q + + G PMVA SP R++ + ANP+E+Q PW + +F+ +S+ PAFQQL++
Sbjct: 177 QPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSILMKQLQQQQPNDKTNIQGMTGTPMVASSPERHDGGLQ-ANPVEVQTYQPPW---KVLSDFA----LQSDIDQPAFQQLVN 313
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Xenopus
Match: ISL1 (ISL LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6132]) HSP 1 Score: 162.54 bits (410), Expect = 1.579e-44 Identity = 75/134 (55.97%), Postives = 94/134 (70.15%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
D G KR I SLCVGCG I D++ILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +L+ CA CN G K+D+V+ S++YHI C +CVAC+R L GDEFA+R +G+ C DH
Sbjct: 3 DMGDPPKKKRLI---SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYIRLYGIKCAKCNIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133 HSP 2 Score: 139.043 bits (349), Expect = 4.995e-36 Identity = 65/72 (90.28%), Postives = 69/72 (95.83%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQ 1225
+KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR I++KQ+ Q Q
Sbjct: 179 EKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSILMKQLQQQQ 250
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Xenopus
Match: isl2 (ISL LIM homeobox 2 [Source:NCBI gene;Acc:100306962]) HSP 1 Score: 156.377 bits (394), Expect = 3.877e-42 Identity = 87/151 (57.62%), Postives = 105/151 (69.54%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQM------DQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSND-SAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+ I++KQ+ D+ G L G PMVAGSP+R++ + + +E+Q PW + D + +D PAFQQL+S
Sbjct: 181 QTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQLNDKTSLQG-----LTGTPMVAGSPIRHDSAVQ-GSAVEVQTYQPPWK--------ALSDFALQSDLDQPAFQQLVS 317 HSP 2 Score: 142.51 bits (358), Expect = 4.562e-37 Identity = 60/119 (50.42%), Postives = 82/119 (68.91%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
++CVGCG I D++ILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +LF C C L +S+ V+ VG R+YH C +C C+R L G+E ++R ++C +H
Sbjct: 45 AVCVGCGSHILDQYILRVSPDLEWHAACLKCAECSQYLDENCTCFVRDGKTYCKRDYIRLFSARCPRCQGTLPRSELVMRVGERVYHTDCFRCSVCSRRLLPGEEISLRDQDLLCGAEH 163
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Xenopus
Match: isl2 (ISL LIM homeobox 2 [Source:NCBI gene;Acc:100306962]) HSP 1 Score: 155.992 bits (393), Expect = 4.587e-42 Identity = 87/151 (57.62%), Postives = 106/151 (70.20%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQM------DQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGS-EEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+ I++KQ+ D+ G L G PMVAGSP+R++ + + +E+Q PW + +F +S+ PAFQQL+S
Sbjct: 161 QTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQLNDKTSLQG-----LTGTPMVAGSPIRHDSAVQ-GSAVEVQTYQPPWKALSDFA--------LQSDLDQPAFQQLVS 297 HSP 2 Score: 142.895 bits (359), Expect = 2.519e-37 Identity = 60/119 (50.42%), Postives = 82/119 (68.91%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
++CVGCG I D++ILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +LF C C L +S+ V+ VG R+YH C +C C+R L G+E ++R ++C +H
Sbjct: 25 AVCVGCGSHILDQYILRVSPDLEWHAACLKCAECSQYLDENCTCFVRDGKTYCKRDYIRLFSARCPRCQGTLPRSELVMRVGERVYHTDCFRCSVCSRRLLPGEEISLRDQDLLCGAEH 143
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Xenopus
Match: zfp36l2 (ZFP36 ring finger protein-like 2 [Source:Xenbase;Acc:XB-GENE-971012]) HSP 1 Score: 125.561 bits (314), Expect = 7.714e-31 Identity = 54/116 (46.55%), Postives = 74/116 (63.79%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLF-LQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVIC 520
+LC GCGG I+D++ L + D +WH RCL+C +C L+ + TCF KDG YCKEDY + F +Q CA C+ G+ S+ V+ +YH+SC C CN+ L TGD F M+ N V C
Sbjct: 59 ALCAGCGGKISDRYYL-LAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARESVYHLSCFTCTTCNKTLSTGDHFGMKENLVYC 173 HSP 2 Score: 61.2326 bits (147), Expect = 1.917e-9 Identity = 28/60 (46.67%), Postives = 40/60 (66.67%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 1189
QKT R+RT QL T+++ +A N PDA +QL + TGL+ RV++VWFQN R K ++
Sbjct: 255 QKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRR 314
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Mouse
Match: Isl2 (insulin related protein 2 (islet 2) [Source:MGI Symbol;Acc:MGI:109156]) HSP 1 Score: 165.622 bits (418), Expect = 1.694e-45 Identity = 88/146 (60.27%), Postives = 105/146 (71.92%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGS-EEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+ I++KQ+ Q Q L G P+VAGSP+R+E + + +E+Q PW + EF +S+ PAFQQL+S
Sbjct: 187 QAEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKASLQGLTGTPLVAGSPIRHENAVQ-GSAVEVQTYQPPWKALSEFA--------LQSDLDQPAFQQLVS 323 HSP 2 Score: 151.754 bits (382), Expect = 2.185e-40 Identity = 68/132 (51.52%), Postives = 88/132 (66.67%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSAS 571
++CVGCG I D+FILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +LF CA C G SD V+ +YHI C +C C+R L GDEF++R + ++C DH L LE +A+
Sbjct: 25 AMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAQCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHG----LLLERAAA 152
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Mouse
Match: Isl1 (ISL1 transcription factor, LIM/homeodomain [Source:MGI Symbol;Acc:MGI:101791]) HSP 1 Score: 164.466 bits (415), Expect = 1.874e-45 Identity = 75/134 (55.97%), Postives = 94/134 (70.15%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
D G KR I SLCVGCG I D++ILRV PDLEWHA CL+C +CN+ LDE TCFV+DGKTYCK DY +L+ CA C+ G K+D+V+ S++YHI C +CVAC+R L GDEFA+R +G+ C DH
Sbjct: 3 DMGDPPKKKRLI---SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133 HSP 2 Score: 149.058 bits (375), Expect = 7.917e-40 Identity = 82/142 (57.75%), Postives = 94/142 (66.20%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR IM+KQ+ Q Q P ANP+E+Q PW + +F+ +S+ PAFQQL++
Sbjct: 179 EKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQ-----------------------PNDKTANPVEVQSYQPPW---KVLSDFA----LQSDIDQPAFQQLVN 290
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Mouse
Match: Isl1 (ISL1 transcription factor, LIM/homeodomain [Source:MGI Symbol;Acc:MGI:101791]) HSP 1 Score: 165.236 bits (417), Expect = 1.983e-45 Identity = 89/145 (61.38%), Postives = 107/145 (73.79%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR IM+KQ+ Q Q + + G PMVA SP R++ + ANP+E+Q PW + +F+ +S+ PAFQQL++
Sbjct: 177 QPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQ-ANPVEVQSYQPPW---KVLSDFA----LQSDIDQPAFQQLVN 313 HSP 2 Score: 164.851 bits (416), Expect = 2.406e-45 Identity = 75/134 (55.97%), Postives = 94/134 (70.15%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
D G KR I SLCVGCG I D++ILRV PDLEWHA CL+C +CN+ LDE TCFV+DGKTYCK DY +L+ CA C+ G K+D+V+ S++YHI C +CVAC+R L GDEFA+R +G+ C DH
Sbjct: 3 DMGDPPKKKRLI---SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Mouse
Match: Isl2 (insulin related protein 2 (islet 2) [Source:MGI Symbol;Acc:MGI:109156]) HSP 1 Score: 140.198 bits (352), Expect = 1.059e-38 Identity = 62/115 (53.91%), Postives = 80/115 (69.57%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVIC 520
++CVGCG I D+FILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +LF CA C G SD V+ +YHI C +C C+R L GDEF++R + ++C
Sbjct: 36 AMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAQCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLC 150
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Mouse
Match: Lhx9 (LIM homeobox protein 9 [Source:MGI Symbol;Acc:MGI:1316721]) HSP 1 Score: 122.865 bits (307), Expect = 6.444e-30 Identity = 53/116 (45.69%), Postives = 74/116 (63.79%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLF-LQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVIC 520
+LC GCGG I+D++ L + D +WH RCL+C +C L+ + TCF KDG YCKEDY + F +Q CA C+ G+ S+ V+ +YH+SC C CN+ L TGD F M+ + V C
Sbjct: 60 ALCAGCGGKISDRYYL-LAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYC 174 HSP 2 Score: 63.1586 bits (152), Expect = 3.786e-10 Identity = 32/78 (41.03%), Postives = 47/78 (60.26%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGID 1243
QKT R+RT QL T+++ +A N PDA +QL + TGL+ RV++VWFQN R K ++ + Q+ GG+D
Sbjct: 256 QKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLL-------RQENGGVD 326
BLAST of insulin gene enhancer protein isl-1 vs. UniProt/SwissProt
Match: sp|P50212|ISL2B_ONCTS (Insulin gene enhancer protein ISL-2B (Fragment) OS=Oncorhynchus tshawytscha OX=74940 GN=isl2b PE=2 SV=1) HSP 1 Score: 167.548 bits (423), Expect = 1.282e-45 Identity = 88/146 (60.27%), Postives = 105/146 (71.92%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGS-EEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR I +KQ+ Q + + L G PMVAGSP+R++ + NP+E+Q PW + EF +S+ PAF+QL+S
Sbjct: 168 QSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRTIFMKQLQQQHHIDKTNLQGLTGTPMVAGSPIRHDNTV-LGNPVEVQTYQPPWKALSEFA--------LQSDLDQPAFRQLVS 304 HSP 2 Score: 146.747 bits (369), Expect = 4.979e-38 Identity = 66/132 (50.00%), Postives = 88/132 (66.67%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSAS 571
++CVGCG I D++ILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +LF CA CN G SD V+ +YH+ C +C C+R L GDEF++R ++C DH L LE +++
Sbjct: 7 AMCVGCGSQIHDQYILRVAPDLEWHAACLKCSECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCNIGFCSSDLVMRARDNVYHMECFRCSVCSRQLVPGDEFSLRDEELLCRADHG----LLLERASA 134
BLAST of insulin gene enhancer protein isl-1 vs. UniProt/SwissProt
Match: sp|P53408|ISL2A_ONCTS (Insulin gene enhancer protein ISL-2A OS=Oncorhynchus tshawytscha OX=74940 GN=isl2a PE=2 SV=1) HSP 1 Score: 167.548 bits (423), Expect = 2.317e-45 Identity = 88/146 (60.27%), Postives = 104/146 (71.23%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGS-EEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR I +KQ+ Q + L G P+VAGSP+R++ + NP+E+Q PW + EF +S+ PAFQQL+S
Sbjct: 186 QSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIFMKQLQQQHHSDKTNLQGLTGTPLVAGSPIRHDNTVQ-GNPVEVQTYQPPWKALSEFA--------LQSDLDQPAFQQLVS 322 HSP 2 Score: 147.132 bits (370), Expect = 5.267e-38 Identity = 68/134 (50.75%), Postives = 87/134 (64.93%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
D G S K I ++CVGCG I D++ILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +LF CA CN G SD V+ +YH+ C +C C+R L GDEF++R ++C DH
Sbjct: 13 DMGDHSKKKSGI---AMCVGCGSQIHDQYILRVAPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCANCNIGFCSSDLVMRARDNVYHMECFRCSVCSRHLLPGDEFSLRDEELLCRADH 143
BLAST of insulin gene enhancer protein isl-1 vs. UniProt/SwissProt
Match: sp|P53405|ISL1_DANRE (Insulin gene enhancer protein isl-1 OS=Danio rerio OX=7955 GN=isl1 PE=2 SV=1) HSP 1 Score: 166.777 bits (421), Expect = 3.402e-45 Identity = 76/134 (56.72%), Postives = 94/134 (70.15%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
D G KR I SLCVGCG I D++ILRV PDLEWHA CL+C +CN+ LDE TCFV+DGKTYCK DY +L+ CA CN G K+D+V+ S++YHI C +CVAC+R L GDEFA+R +G+ C DH
Sbjct: 3 DMGDPPKKKRLI---SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCNIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133 HSP 2 Score: 157.147 bits (396), Expect = 1.263e-41 Identity = 86/145 (59.31%), Postives = 105/145 (72.41%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR I++KQ+ Q Q + + G PMVA SP R++ + AN +E+Q PW + +F+ +S+ PAFQQL++
Sbjct: 177 QPEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSILMKQLQQQQPNDKTNIQGMTGTPMVATSPERHDGGLQ-ANQVEVQSYQPPW---KVLSDFA----LQSDIDQPAFQQLVN 313
BLAST of insulin gene enhancer protein isl-1 vs. UniProt/SwissProt
Match: sp|P53406|ISL2A_DANRE (Insulin gene enhancer protein isl-2a OS=Danio rerio OX=7955 GN=isl2a PE=2 SV=1) HSP 1 Score: 167.162 bits (422), Expect = 3.639e-45 Identity = 88/146 (60.27%), Postives = 106/146 (72.60%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGS-EEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+ I++KQ+ Q Q + L G P+VAGSP+R++ + NP+E+Q PW + EF +S+ PAFQQL+S
Sbjct: 187 QSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHNDKTNLQGLTGTPLVAGSPIRHDTTVQ-GNPVEVQTYQPPWKALSEFA--------LQSDLDQPAFQQLVS 323 HSP 2 Score: 148.288 bits (373), Expect = 2.258e-38 Identity = 68/134 (50.75%), Postives = 87/134 (64.93%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
D G S K I ++CVGCG I D++ILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +LF CA CN G SD V+ +YH+ C +C C+R L GDEF++R ++C DH
Sbjct: 13 DMGDHSKKKSGI---AMCVGCGSQIHDQYILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCNIGFCSSDLVMRARDNVYHMECFRCSVCSRHLLPGDEFSLRDEELLCRADH 143
BLAST of insulin gene enhancer protein isl-1 vs. UniProt/SwissProt
Match: sp|Q9CXV0|ISL2_MOUSE (Insulin gene enhancer protein ISL-2 OS=Mus musculus OX=10090 GN=Isl2 PE=1 SV=2) HSP 1 Score: 165.622 bits (418), Expect = 1.185e-44 Identity = 88/146 (60.27%), Postives = 105/146 (71.92%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGS-EEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+ I++KQ+ Q Q L G P+VAGSP+R+E + + +E+Q PW + EF +S+ PAFQQL+S
Sbjct: 187 QAEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKASLQGLTGTPLVAGSPIRHENAVQ-GSAVEVQTYQPPWKALSEFA--------LQSDLDQPAFQQLVS 323 HSP 2 Score: 151.754 bits (382), Expect = 1.529e-39 Identity = 68/132 (51.52%), Postives = 88/132 (66.67%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSAS 571
++CVGCG I D+FILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +LF CA C G SD V+ +YHI C +C C+R L GDEF++R + ++C DH L LE +A+
Sbjct: 25 AMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAQCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHG----LLLERAAA 152
BLAST of insulin gene enhancer protein isl-1 vs. TrEMBL
Match: V5SM21 (Insulin gene enhancer protein isl-1 OS=Schmidtea mediterranea OX=79327 GN=islet1 PE=2 SV=1) HSP 1 Score: 959.903 bits (2480), Expect = 0.000e+0 Identity = 517/517 (100.00%), Postives = 517/517 (100.00%), Query Frame = 2
Query: 101 MTASLELEDCDDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSASILTRTERLPQSHQPASPLKQPKQELETESLMKIEDETNSRKSGCCRNYLEVVSDERLLMDTINNNTSGNISRANSRLSYVKGXXXXXXXXXXXXXXXXXXXXVCGNQSINGGHGGTIXXXXXXXXXXXXVTCTGNVKLSGTKRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLISAYHHLSRNGXXXXXXXXXXXXXXXXXQPLSNSNHPNLSFLTAMGLLSGARNGDLDDSPHDSFVGKLISYSVD 1651
MTASLELEDCDDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSASILTRTERLPQSHQPASPLKQPKQELETESLMKIEDETNSRKSGCCRNYLEVVSDERLLMDTINNNTSGNISRANSRLSYVKGILDDSSMNSDIDDISQDGSSVCGNQSINGGHGGTISAAGSLPSSGGGVTCTGNVKLSGTKRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLISAYHHLSRNGPCPPPPLMSLSHSPAHSQPLSNSNHPNLSFLTAMGLLSGARNGDLDDSPHDSFVGKLISYSVD
Sbjct: 1 MTASLELEDCDDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSASILTRTERLPQSHQPASPLKQPKQELETESLMKIEDETNSRKSGCCRNYLEVVSDERLLMDTINNNTSGNISRANSRLSYVKGILDDSSMNSDIDDISQDGSSVCGNQSINGGHGGTISAAGSLPSSGGGVTCTGNVKLSGTKRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLISAYHHLSRNGPCPPPPLMSLSHSPAHSQPLSNSNHPNLSFLTAMGLLSGARNGDLDDSPHDSFVGKLISYSVD 517
BLAST of insulin gene enhancer protein isl-1 vs. TrEMBL
Match: F8WQS6 (Insulin gene enhancer protein isl-1 OS=Dugesia japonica OX=6161 GN=Djislet PE=2 SV=1) HSP 1 Score: 908.286 bits (2346), Expect = 0.000e+0 Identity = 498/517 (96.32%), Postives = 509/517 (98.45%), Query Frame = 2
Query: 101 MTASLELEDCDDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSASILTRTERLPQSHQPASPLKQPKQELETESLMKIEDETNSRKSGCCRNYLEVVSDERLLMDTINNNTSGNISRANSRLSYVKGXXXXXXXXXXXXXXXXXXXXVCGNQSINGGHGGTIXXXXXXXXXXXXVTCTGNVKLSGTKRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLISAYHHLSRNGXXXXXXXXXXXXXXXXXQPLSNSNHPNLSFLTAMGLLSGARNGDLDDSPHDSFVGKLISYSVD 1651
MTASLELEDCDDG RSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNR+LQTGDEFA+RPNGVICLHDHQRDGHLF+ENS ++LTR ERL +HQP SP+KQPKQELETESL+KIEDETNSRKSGCCRNYL+VVSDERLLMDTINNN +GNISRANSRLSYVKGILDDSSMNSDIDDISQDGSSVCGNQSINGGHGGTISAAGSLPSSGGGVTCTGN K+SGTKRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLISAYHHLSRNGPCPPPPLMSLSHSPAHSQPLSNSNHPNLSFLTAMGLLSGARNGDLDDSPHDSFVGKLISYSVD
Sbjct: 1 MTASLELEDCDDGVRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRILQTGDEFALRPNGVICLHDHQRDGHLFIENSGNLLTRPERLATNHQPPSPIKQPKQELETESLLKIEDETNSRKSGCCRNYLDVVSDERLLMDTINNNNTGNISRANSRLSYVKGILDDSSMNSDIDDISQDGSSVCGNQSINGGHGGTISAAGSLPSSGGGVTCTGNAKMSGTKRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLISAYHHLSRNGPCPPPPLMSLSHSPAHSQPLSNSNHPNLSFLTAMGLLSGARNGDLDDSPHDSFVGKLISYSVD 517
BLAST of insulin gene enhancer protein isl-1 vs. TrEMBL
Match: A0A0V1PB55 (Insulin enhancer-like protein OS=Trichinella sp. T8 OX=92180 GN=ISL1 PE=4 SV=1) HSP 1 Score: 272.707 bits (696), Expect = 3.393e-81 Identity = 170/397 (42.82%), Postives = 222/397 (55.92%), Query Frame = 2
Query: 161 SIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSASILTRTERLPQSHQPASPLKQPKQELETESLMKIEDETNSRKSGCCRNYLEVVSDERLLMDTINNNTSGNISRANSRLSYVKGXXXXXXXXXXXXXXXXXXXXVCGNQSINGGHGGTIXXXXXXXXXXXXVTCTGNVKLSGTKRSKEQ-KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQ----HQQVGGIDCPLQGV-PMVAGSPMRNEPPISCANPLEIQQ 1333
S K S+C GCG I D++ILRV PDLEWHA CL+CV C + LDE TCFV+DGK YCK DY +LF C+ C ++DYV+ + +YHISC KCV C R L GDEFA+R + C D++ L NS + T T Q + ++ ++ L S + +S + C RN + D+ + + + N N+ S SY G CG + + S G + K +E+ KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+Q+++KQ+ Q +Q + GI +QGV P++A SP R++ P+ A +E+QQ
Sbjct: 42 SRKRSSICNGCGHEILDQYILRVSPDLEWHAACLKCVDCRQFLDETCTCFVRDGKPYCKLDYVRLFGVRCSKCGEVFDRNDYVMRAKNNLYHISCFKCVVCTRPLLPGDEFALRHIALYCKADYE----LAERNSLCLSTETSNESQLEEHSADVQATLNALHHPS---GQSPLSSESTSCYRN---LGQDDSPV--SKSGNAVLNMGLGTSGSSYSNG---------------------CGQST----------PELTSTSPQVSAGSVGQQPFAQKKDKREKPKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKQLIMKQIQQQHVKNQTLNGIR--MQGVGPLIASSPSRHDVPLISA--IEVQQ 391
BLAST of insulin gene enhancer protein isl-1 vs. TrEMBL
Match: A0A0V1L955 (Insulin enhancer-like protein OS=Trichinella nativa OX=6335 GN=ISL1 PE=4 SV=1) HSP 1 Score: 272.707 bits (696), Expect = 3.452e-81 Identity = 170/397 (42.82%), Postives = 222/397 (55.92%), Query Frame = 2
Query: 161 SIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSASILTRTERLPQSHQPASPLKQPKQELETESLMKIEDETNSRKSGCCRNYLEVVSDERLLMDTINNNTSGNISRANSRLSYVKGXXXXXXXXXXXXXXXXXXXXVCGNQSINGGHGGTIXXXXXXXXXXXXVTCTGNVKLSGTKRSKEQ-KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQ----HQQVGGIDCPLQGV-PMVAGSPMRNEPPISCANPLEIQQ 1333
S K S+C GCG I D++ILRV PDLEWHA CL+CV C + LDE TCFV+DGK YCK DY +LF C+ C ++DYV+ + +YHISC KCV C R L GDEFA+R + C D++ L NS + T T Q + ++ ++ L S + +S + C RN + D+ + + + N N+ S SY G CG + + S G + K +E+ KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+Q+++KQ+ Q +Q + GI +QGV P++A SP R++ P+ A +E+QQ
Sbjct: 38 SRKRSSICNGCGHEILDQYILRVSPDLEWHAACLKCVDCRQFLDETCTCFVRDGKPYCKLDYVRLFGVRCSKCGEVFDRNDYVMRAKNNLYHISCFKCVVCTRPLLPGDEFALRHIALYCKADYE----LAERNSLCLSTETSNESQLEEHSADVQATLNALHHPS---GQSPLSSESTSCYRN---LGQDDSPV--SKSGNVVLNMGLGTSGSSYSNG---------------------CGQST----------PELTSTSPQVSAGSVGQQPFAQKKDKREKPKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKQLIMKQIQQQHVKNQTLNGIR--MQGVGPLIASSPSRHDVPLISA--IEVQQ 387
BLAST of insulin gene enhancer protein isl-1 vs. TrEMBL
Match: A0A1Y3ELC9 (Putative LIM domain protein OS=Trichinella nativa OX=6335 GN=D917_08123 PE=4 SV=1) HSP 1 Score: 272.707 bits (696), Expect = 3.526e-81 Identity = 170/397 (42.82%), Postives = 222/397 (55.92%), Query Frame = 2
Query: 161 SIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSASILTRTERLPQSHQPASPLKQPKQELETESLMKIEDETNSRKSGCCRNYLEVVSDERLLMDTINNNTSGNISRANSRLSYVKGXXXXXXXXXXXXXXXXXXXXVCGNQSINGGHGGTIXXXXXXXXXXXXVTCTGNVKLSGTKRSKEQ-KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQ----HQQVGGIDCPLQGV-PMVAGSPMRNEPPISCANPLEIQQ 1333
S K S+C GCG I D++ILRV PDLEWHA CL+CV C + LDE TCFV+DGK YCK DY +LF C+ C ++DYV+ + +YHISC KCV C R L GDEFA+R + C D++ L NS + T T Q + ++ ++ L S + +S + C RN + D+ + + + N N+ S SY G CG + + S G + K +E+ KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+Q+++KQ+ Q +Q + GI +QGV P++A SP R++ P+ A +E+QQ
Sbjct: 38 SRKRSSICNGCGHEILDQYILRVSPDLEWHAACLKCVDCRQFLDETCTCFVRDGKPYCKLDYVRLFGVRCSKCGEVFDRNDYVMRAKNNLYHISCFKCVVCTRPLLPGDEFALRHIALYCKADYE----LAERNSLCLSTETSNESQLEEHSADVQATLNALHHPS---GQSPLSSESTSCYRN---LGQDDSPV--SKSGNVVLNMGLGTSGSSYSNG---------------------CGQST----------PELTSTSPQVSAGSVGQQPFAQKKDKREKPKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKQLIMKQIQQQHVKNQTLNGIR--MQGVGPLIASSPSRHDVPLISA--IEVQQ 387
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Cavefish
Match: isl2a (ISL LIM homeobox 2 [Source:NCBI gene;Acc:103023279]) HSP 1 Score: 169.859 bits (429), Expect = 3.066e-47 Identity = 89/146 (60.96%), Postives = 106/146 (72.60%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGS-EEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR I++KQ+ Q Q + L G P+VAGSP+R++ + NP+E+Q PW + EF +S+ PAFQQL+S
Sbjct: 187 QSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSILMKQLQQQQHSDKTNLQGLTGTPLVAGSPIRHDNTVQ-GNPVEVQTYQPPWKALSEFA--------LQSDLEQPAFQQLVS 323 HSP 2 Score: 148.673 bits (374), Expect = 1.633e-39 Identity = 71/147 (48.30%), Postives = 92/147 (62.59%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSAS 571
D G S K I ++CVGCG I D++ILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +LF CA CN G S+ V+ +YH+ C +C C+R L GDEF++R ++C DH L LE A+
Sbjct: 13 DMGDHSKKKSGI---AMCVGCGSQIHDQYILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCNSGFCSSELVMRARDNVYHMECFRCSVCSRHLLPGDEFSLREEELLCRADHG----LLLERGAA 152
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Cavefish
Match: isl1 (ISL LIM homeobox 1 [Source:NCBI gene;Acc:103024036]) HSP 1 Score: 165.236 bits (417), Expect = 8.813e-46 Identity = 76/134 (56.72%), Postives = 94/134 (70.15%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
D G KR I SLCVGCG I D++ILRV PDLEWHA CL+C +CN+ LDE TCFV+DGKTYCK DY +L+ CA CN G K+D+V+ S++YHI C +CVAC+R L GDEFA+R +G+ C DH
Sbjct: 3 DMGDPPKKKRLI---SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCNVGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133 HSP 2 Score: 145.976 bits (367), Expect = 1.137e-38 Identity = 87/156 (55.77%), Postives = 108/156 (69.23%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQM-----DQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLISAYHHLSRNG 1462
+KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR +++KQ+ + + G + G PMVA SP R++ + A+ +E+Q PW + +F+ +S+ PAFQQL+SA +R G
Sbjct: 179 EKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSLLMKQLQQQQPNDKTNIQG----MTGTPMVAASPERHDGGLQ-ASQVEVQTYQPPW---KVLSDFA----LQSDIDQPAFQQLVSAGEMQARRG 322
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Cavefish
Match: isl2b (ISL LIM homeobox 2b [Source:NCBI gene;Acc:30151]) HSP 1 Score: 148.673 bits (374), Expect = 1.513e-39 Identity = 80/142 (56.34%), Postives = 96/142 (67.61%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR I++KQ+ QH+ + L +V GSP+R + + +E+Q EF H D+ + P FQ L++
Sbjct: 180 EKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSILMKQLQQHRDQTDLQV-LSSSALVEGSPVRPDHSLM-GQHVEVQSYTAWKSLSEFT---LHSDLEQ-----PTFQHLVT 311 HSP 2 Score: 148.673 bits (374), Expect = 1.656e-39 Identity = 69/150 (46.00%), Postives = 95/150 (63.33%), Query Frame = 2
Query: 92 IKIMTASLELEDCDDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRD 541
++I+ +S L+D D + S ++CVGCG I D++ILRV PDLEWHA CL+C +C++ LDE TCFV++GKTYCK DY +LF CA C G SD V+ +YHI C +C AC R L G+EF++R + ++C DH D
Sbjct: 2 VEIIFSSSFLDDMGDHIKKKS-----GLAMCVGCGIQIHDQYILRVSPDLEWHAACLKCAECSQYLDENCTCFVREGKTYCKRDYVRLFGVKCAKCGLGFTNSDLVMRARDSVYHIKCFRCSACGRQLLPGEEFSVREDALLCRGDHGPD 146
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Cavefish
Match: ENSAMXT00000055018.1 (insulin gene enhancer protein ISL-1-like [Source:NCBI gene;Acc:103021841]) HSP 1 Score: 134.42 bits (337), Expect = 9.750e-35 Identity = 57/117 (48.72%), Postives = 74/117 (63.25%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVG-SRIYHISCMKCVACNRVLQTGDEFAMRPNGVICL 523
SLCVGCG I D+FILRV PDLEWH CL+C +C + LDE TCF++DGK CKEDY +L+ C+ C R DY + G +YH+ C +C C+R L GD F +R + C+
Sbjct: 16 SLCVGCGHQILDRFILRVFPDLEWHTACLKCSECEQHLDESLTCFIRDGKALCKEDYSRLYSTKCSRCRRSFSSGDYGMRAGVGAVYHVQCFRCAGCDRQLVPGDRFTLRDGNLHCV 132 HSP 2 Score: 116.316 bits (290), Expect = 2.632e-28 Identity = 55/80 (68.75%), Postives = 66/80 (82.50%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVK--------QMDQHQ 1225
Q+ TRVRTVL+E QLHTL++CY+ANPRPDAL+KEQLVE+TGLSPRVIRVWFQNKRCKDKKR + Q++QH+
Sbjct: 166 QRMTRVRTVLSEAQLHTLQSCYSANPRPDALLKEQLVELTGLSPRVIRVWFQNKRCKDKKRSTAARNTQNRPNQQVNQHE 245
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Cavefish
Match: ENSAMXT00000031017.1 (insulin gene enhancer protein ISL-1-like [Source:NCBI gene;Acc:103021841]) HSP 1 Score: 134.42 bits (337), Expect = 1.286e-34 Identity = 64/149 (42.95%), Postives = 85/149 (57.05%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVG-SRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSASILTRTERLPQSHQPAS 619
SLCVGCG I D+FILRV PDLEWH CL+C +C + LDE TCF++DGK CKEDY +L+ C+ C R DY + G +YH+ C +C C+R L GD F +R + C+ Q + ++ IL RL Q + S
Sbjct: 25 SLCVGCGHQILDRFILRVFPDLEWHTACLKCSECEQHLDESLTCFIRDGKALCKEDYSRLYSTKCSRCRRSFSSGDYGMRAGVGAVYHVQCFRCAGCDRQLVPGDRFTLRDGNLHCVSRTQTCREVTAGKNSYILYILYRLHQKRKNKS 173 HSP 2 Score: 121.709 bits (304), Expect = 4.034e-30 Identity = 72/154 (46.75%), Postives = 93/154 (60.39%), Query Frame = 2
Query: 995 KRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVK--QMDQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLISAYHHL 1450
K + + TRVRTVL+E QLHTL++CY+ANPRPDAL+KEQLVE+TGLSPRVIRVWFQNKRCKDKKR + Q +QQV Q V SP + + PL++Q W + +FS S S+ + QQ +S +H+
Sbjct: 170 KNKSKSRMTRVRTVLSEAQLHTLQSCYSANPRPDALLKEQLVELTGLSPRVIRVWFQNKRCKDKKRSTAARNTQNRPNQQVN------QHVNFFTASPDSLDQEV-LMTPLDLQNFQPSW---KLLTSFSFQ--SDSDYDSTQHQQPVSRLNHI 311
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002189.1 (pep scaffold:Pmarinus_7.0:GL483992:1961:4872:1 gene:ENSPMAG00000001979.1 transcript:ENSPMAT00000002189.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 164.851 bits (416), Expect = 8.216e-47 Identity = 92/160 (57.50%), Postives = 107/160 (66.88%), Query Frame = 2
Query: 959 VTCTGNVKLSGTKRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQI-PGPWGSEEFGPNFSHGDISRSNDSAPAFQQLI 1432
V + ++ LSG S +K TRVRTVLNEKQL TLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR I++KQM Q + L G P+VAGSP+ +E I NP+E+Q P PW + S +S D P FQ L+
Sbjct: 98 VHSSRSLHLSGGIPSGPEKATRVRTVLNEKQLQTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSILMKQMQQQHHADKTNLQGLTGTPLVAGSPVPHEAAIP-GNPVEVQSFQPAPWKT------LSEFALSSDLDQGP-FQHLM 249 HSP 2 Score: 60.4622 bits (145), Expect = 2.412e-10 Identity = 27/61 (44.26%), Postives = 37/61 (60.66%), Query Frame = 2
Query: 350 KLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRP-NGVICLHD 529
+LF CA CN K+D+V+ S IYH+ C +C C+R L GDEFA+R G++C D
Sbjct: 1 RLFGIKCAKCNASFSKTDFVMRARSHIYHMECFRCETCSRQLLPGDEFALRDGGGLLCRAD 61
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Sea Lamprey
Match: lmo4b (LIM domain only 4b [Source:ZFIN;Acc:ZDB-GENE-030131-3570]) HSP 1 Score: 85.5001 bits (210), Expect = 1.147e-19 Identity = 42/119 (35.29%), Postives = 60/119 (50.42%), Query Frame = 2
Query: 182 CVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGL-DEKNTCFVKDGKTYCKEDYQKLFLQ--VCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHD 529
C GCGG I D+F+L D WH+RCL+C C L D +C+ + G C++DY ++F C AC + + S+ V+ +YH+ C C C L GD F + C HD
Sbjct: 18 CAGCGGKIADRFLLYSM-DCYWHSRCLKCSCCQAQLGDLGTSCYTRQGMILCRDDYIRMFGSSGACNACGQSIPASELVMKTQGNVYHLKCFACATCRTRLVPGDRFHYVNGSLFCEHD 135
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Sea Lamprey
Match: lmo2 (LIM domain only 2 (rhombotin-like 1) [Source:NCBI gene;Acc:30332]) HSP 1 Score: 70.8626 bits (172), Expect = 9.398e-15 Identity = 38/120 (31.67%), Postives = 61/120 (50.83%), Query Frame = 2
Query: 179 LCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDE-KNTCFVKDGKTYCKEDYQKLFLQV--CAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHD 529
+C GC I+D+++L+ WH CL C C L E + K G+ C+ DY +LF Q CA+C + + + + V ++YH+ C KC AC + GD + + + +IC D
Sbjct: 29 MCGGCRQPISDRYLLKAIEQF-WHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGHCASCGKRIRAFEMTMRVRDKVYHLECFKCAACQKHFCVGDRYLLVNSDIICEQD 147
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Sea Lamprey
Match: lmo2 (LIM domain only 2 (rhombotin-like 1) [Source:NCBI gene;Acc:30332]) HSP 1 Score: 68.9366 bits (167), Expect = 4.222e-14 Identity = 38/120 (31.67%), Postives = 61/120 (50.83%), Query Frame = 2
Query: 179 LCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDE-KNTCFVKDGKTYCKEDYQKLFLQV--CAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHD 529
+C GC I+D+++L+ WH CL C C L E + K G+ C+ DY +LF Q CA+C + + + + V ++YH+ C KC AC + GD + + + +IC D
Sbjct: 28 MCGGCRQPISDRYLLKAIEQF-WHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGHCASCGKRIRAFEMTMRVRDKVYHLECFKCAACQKHFCVGDRYLLVNSDIICEQD 146
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Sea Lamprey
Match: ablim1a (actin binding LIM protein 1a [Source:ZFIN;Acc:ZDB-GENE-080219-41]) HSP 1 Score: 71.633 bits (174), Expect = 2.577e-13 Identity = 53/186 (28.49%), Postives = 78/186 (41.94%), Query Frame = 2
Query: 146 SNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMR---------------------PNGVICLHDHQRDGHLFLENSASILTRTERLPQS--HQPASPLKQP 634
+ + + I + + C GCG I + L D +WH C +C C + L KDG YC++DYQ F C C + + + VL G + YH SC +CV C ++ G+E M+ PN C HD L + ++ +L P S HQP P +QP
Sbjct: 129 ATNAKDIGASTNCTGCGSDIMNGQALLAL-DKQWHLGCFKCKTCGKVLT--GEYISKDGVPYCEQDYQSQFGIKCEECGKFI--TGKVLEAGEKHYHPSCARCVRCKQMFSEGEEMFMQGSSIWHPECKRAERAEEKQKTPNLPSCWHDKTTACCLAVSDAMYLLPVEALSPASLAHQPKGP-QQP 308
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Yeast
Match: PXL1 (Protein that localizes to sites of polarized growth; required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; contains LIM domains and has similarity to metazoan paxillin; relocalizes from bud neck to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000001798]) HSP 1 Score: 48.1358 bits (113), Expect = 3.484e-6 Identity = 30/128 (23.44%), Postives = 57/128 (44.53%), Query Frame = 2
Query: 182 CVGCGGAITDKFILRVQPDL---EWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLH----KSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICL---HDHQ 535
C CG +T K + + + +WH C +C++C ++ C++ + YC++ Y + +C C+ + ++D V +H+ C+ C C + T D + NG I L HD +
Sbjct: 556 CRACGLEVTGKRMFSKKENELSGQWHRECFKCIECGIKFNKHVPCYILGDEPYCQKHYHEENHSICKVCSNFIEGECLENDKVER-----FHVDCLNCFLCKTAI-TNDYYIF--NGEIPLCGNHDME 675
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Yeast
Match: PHO2 (Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002264]) HSP 1 Score: 46.595 bits (109), Expect = 8.426e-6 Identity = 22/79 (27.85%), Postives = 43/79 (54.43%), Query Frame = 2
Query: 959 VTCTGNVKLSGTKRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQ 1195
++ + N SG +R K RT + L L+ + NP P + ++++ ++ G+ + +R+WFQN+R K +K+Q
Sbjct: 65 MSASSNASDSGPQRPK-------RTRAKGEALDVLKRKFEINPTPSLVERKKISDLIGMPEKNVRIWFQNRRAKLRKKQ 136
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Nematostella
Match: EDO46073 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR95]) HSP 1 Score: 160.229 bits (404), Expect = 2.553e-44 Identity = 68/120 (56.67%), Postives = 88/120 (73.33%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQ 535
S+CVGCG I D++ILRV PDLEWHA CL+C C+ LDEK TCFV++GKTYCK DY +LF CA C+ K+D+V+ ++IYHI C +CVAC+R L GDEFA+R +G+ C DH+
Sbjct: 15 SMCVGCGSQIHDQYILRVAPDLEWHASCLKCADCHMYLDEKCTCFVREGKTYCKRDYVRLFGTKCAKCSLNFSKNDFVMRARNKIYHIDCFRCVACSRQLVPGDEFALREDGLFCKADHE 134 HSP 2 Score: 124.405 bits (311), Expect = 1.576e-31 Identity = 76/154 (49.35%), Postives = 92/154 (59.74%), Query Frame = 2
Query: 986 SGTKRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGI--DCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPG--PWGS-EEFGPNFSHGDISRSNDSAPAFQQLI 1432
S + K + TRVRTVLNEKQLHTLRTCY ANPRPDA+MKEQLVEMTGLSPRVIRVWFQNKRCKDKK K + G P Q +P ++G P N + P + + G PW + +F H ++ + AFQQL+
Sbjct: 170 STPSKRKTDRPTRVRTVLNEKQLHTLRTCYNANPRPDAMMKEQLVEMTGLSPRVIRVWFQNKRCKDKK-----KNPNSLSPTGAPPRTLPQQTLPAISGVPYGNSGSM---RPDAMSDMSGYQPWKALNDFA---MHSEMDQG-----AFQQLV 307
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Nematostella
Match: EDO34370 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPK5]) HSP 1 Score: 110.923 bits (276), Expect = 4.690e-27 Identity = 49/116 (42.24%), Postives = 71/116 (61.21%), Query Frame = 2
Query: 182 CVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVIC-LH 526
CVGC I D+++++V WH +CL+C C+ L + TC+ KDGK YCK DY + F CA C R +H +D+V + +YH++C C C R L TG+EFA++ V+C LH
Sbjct: 28 CVGCEAKIVDRYLVKVS-GRAWHTKCLKCCLCSDELGREATCYTKDGKIYCKADYARQFGTKCARCGRSIHANDWVRRAKNCVYHLACFACDNCKRQLSTGEEFALKDGHVLCKLH 142 HSP 2 Score: 57.3806 bits (137), Expect = 5.206e-9 Identity = 27/64 (42.19%), Postives = 37/64 (57.81%), Query Frame = 2
Query: 998 RSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 1189
+S K RVRT E QL L+ + + PD E++ ++TGLS RV +VWFQN R + KK
Sbjct: 174 KSGRHKAKRVRTTFTEDQLQILQANFNIDSNPDGQDLERIAQLTGLSKRVTQVWFQNSRARQKK 237
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Nematostella
Match: EDO43354 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYP5]) HSP 1 Score: 105.145 bits (261), Expect = 1.608e-25 Identity = 46/121 (38.02%), Postives = 73/121 (60.33%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLF-LQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQ 535
++C GCG I ++F L + D EWHA CL+C C LD + TCF KDG C+EDY + F ++ C++C++ + + V+ ++YH++C C C R+L TG+ F MR + C D++
Sbjct: 7 AVCAGCGSRILERFYL-MAVDQEWHADCLKCSDCELRLDNELTCFSKDGVILCREDYYRRFSVKKCSSCSQAISSKELVMRARDQVYHVNCFACDRCKRMLATGEYFGMRGIRIYCKEDYE 126 HSP 2 Score: 55.0694 bits (131), Expect = 1.848e-8 Identity = 26/56 (46.43%), Postives = 36/56 (64.29%), Query Frame = 2
Query: 1022 RVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 1189
RVRT QL ++T +A N PDA +QL + TGL+ RV++VWFQN R K ++
Sbjct: 183 RVRTSFKHHQLRAMKTYFAMNHNPDAKDLKQLSQKTGLTKRVLQVWFQNARAKFRR 238
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Nematostella
Match: LHX1 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9E9]) HSP 1 Score: 86.2705 bits (212), Expect = 2.614e-19 Identity = 43/118 (36.44%), Postives = 66/118 (55.93%), Query Frame = 2
Query: 182 CVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNG-VICLHDH 532
C GC I DKF+L+V D WHA+C++C C L E+ CF ++GK +CK D+ + + C+ C++G+ +D V ++H+ C C C R + TGDE +G IC D+
Sbjct: 5 CAGCQLPIADKFLLKVL-DGVWHAQCVQCSDCKCPLTER--CFSREGKLFCKTDFYRRYGTKCSGCDQGISPNDMVRRAKHLVFHVDCFVCSYCKRQITTGDELYYIGDGSFICRDDY 119 HSP 2 Score: 59.6918 bits (143), Expect = 2.861e-10 Identity = 25/54 (46.30%), Postives = 40/54 (74.07%), Query Frame = 2
Query: 1028 RTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 1189
RT + KQL L++ +AA P+P ++E+L + TGL+ RVI+VWFQN+R K+++
Sbjct: 157 RTTIKAKQLEALKSTFAATPKPSRNIREKLAQETGLNMRVIQVWFQNRRSKERR 210
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Nematostella
Match: EDO37316 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG43]) HSP 1 Score: 78.9518 bits (193), Expect = 2.228e-17 Identity = 46/131 (35.11%), Postives = 64/131 (48.85%), Query Frame = 2
Query: 179 LCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNT-CFVKDGKTYCKEDYQKLFLQ--VCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLEN 562
+C GCG I D+F+L + D WH CL+C C L E T C+ K G CK DY +L+ CA C + + ++ V+ V ++YH+ C C C+ L GD F H +G LF EN
Sbjct: 18 VCAGCGEKIIDRFLL-LALDQYWHVNCLKCSCCEARLGEIGTSCYSKGGMILCKTDYVRLYGNSGACAVCAKLIPATELVMKVLGKVYHLHCFTCTTCHNQLVPGDRF------------HVVNGRLFCEN 135
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Medaka
Match: ISL2 (insulin gene enhancer protein isl-2a [Source:NCBI gene;Acc:101169602]) HSP 1 Score: 167.162 bits (422), Expect = 3.768e-46 Identity = 86/146 (58.90%), Postives = 104/146 (71.23%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSND-SAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+ I++KQ+ Q Q + L G P+VAGSP+R++ + NP+E+Q PW + D++ D PAFQ L+S
Sbjct: 186 QSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQIQQQQHNDKTNLQGLTGTPLVAGSPIRHDTTVQ-GNPVEVQTYQTPWKTL--------SDLALETDLDQPAFQHLVS 322 HSP 2 Score: 151.754 bits (382), Expect = 1.668e-40 Identity = 71/147 (48.30%), Postives = 94/147 (63.95%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSAS 571
D G S K I ++CVGCG I D++ILRV PDLEWHA CL+C +CN+ LDE TCFV+DGKTYCK DY +LF CA CN G SD V+ ++YH+ C +C C+R L GDEF++R + ++C R H LE +++
Sbjct: 13 DMGDHSKKKSGI---AMCVGCGSQIHDQYILRVSPDLEWHAACLKCAECNQYLDETCTCFVRDGKTYCKRDYARLFGIKCAKCNTGFCSSDLVMRAREKVYHMECFRCSVCSRHLLPGDEFSLREDELLC-----RANHDLLERASA 151
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Medaka
Match: ISL2 (insulin gene enhancer protein ISL-3 [Source:NCBI gene;Acc:101174255]) HSP 1 Score: 166.007 bits (419), Expect = 1.096e-45 Identity = 89/150 (59.33%), Postives = 107/150 (71.33%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQ----VGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGS-EEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+ I++KQ+ Q Q V + L G P+VAGSP+R+E + NP+E+Q PW + +F +S+ PAFQQL+S
Sbjct: 188 QSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTVSIFNLQGLTGTPLVAGSPIRHESTVQ-GNPVEVQTYQPPWKALSDFA--------LQSDLDQPAFQQLVS 328 HSP 2 Score: 149.443 bits (376), Expect = 1.153e-39 Identity = 70/147 (47.62%), Postives = 95/147 (64.63%), Query Frame = 2
Query: 92 IKIMTASLELEDCDDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
+ I+ +S L+D D +SK+ ++CVGCG I D++ILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +LF CA CN G SD V+ +YHI C +C C+R L GDEF+++ ++C DH
Sbjct: 2 VDIIFSSSFLDDMGD----HSKKK-PGFAMCVGCGSQIHDQYILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCNLGFSSSDLVMRARDNVYHIECFRCSMCSRQLLPGDEFSLQEGDLLCRADH 143
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Medaka
Match: isl1 (ISL LIM homeobox 1 [Source:NCBI gene;Acc:101165983]) HSP 1 Score: 164.466 bits (415), Expect = 2.909e-45 Identity = 70/119 (58.82%), Postives = 89/119 (74.79%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDH 532
SLCVGCG I D++ILRV PDLEWHA CL+C +C++ LDE TCFV+DGKTYCK DY +L+ CA CN G K+D+V+ S++YHI C +CVAC+R L GDEFA+R +G+ C DH
Sbjct: 15 SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECSQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCNIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133 HSP 2 Score: 149.443 bits (376), Expect = 9.175e-40 Identity = 87/149 (58.39%), Postives = 106/149 (71.14%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQM-----DQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLIS 1435
+ +KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR +++KQ+ + + G + G PMVA SP R++ I ANP+E+Q PW + +F+ +S+ PAFQQL+S
Sbjct: 177 QPEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSLLMKQLQQQQPNDKTNIQG----MTGTPMVAASPERHDGGIQ-ANPVEVQSYQPPW---KVLSDFA----LQSDIDQPAFQQLVS 313
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Medaka
Match: ISL2 (insulin gene enhancer protein isl-2a [Source:NCBI gene;Acc:101169602]) HSP 1 Score: 161.384 bits (407), Expect = 2.844e-44 Identity = 78/118 (66.10%), Postives = 93/118 (78.81%), Query Frame = 2
Query: 1004 KEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCP-LQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGS 1354
+ +KTTRVRTVLNEKQLHTLRTCY ANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+ I++KQ+ Q Q + L G P+VAGSP+R++ + NP+E+Q PW +
Sbjct: 186 QSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQIQQQQHNDKTNLQGLTGTPLVAGSPIRHDTTVQ-GNPVEVQTYQTPWKT 302 HSP 2 Score: 150.984 bits (380), Expect = 1.567e-40 Identity = 71/147 (48.30%), Postives = 94/147 (63.95%), Query Frame = 2
Query: 131 DDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSAS 571
D G S K I ++CVGCG I D++ILRV PDLEWHA CL+C +CN+ LDE TCFV+DGKTYCK DY +LF CA CN G SD V+ ++YH+ C +C C+R L GDEF++R + ++C R H LE +++
Sbjct: 13 DMGDHSKKKSGI---AMCVGCGSQIHDQYILRVSPDLEWHAACLKCAECNQYLDETCTCFVRDGKTYCKRDYARLFGIKCAKCNTGFCSSDLVMRAREKVYHMECFRCSVCSRHLLPGDEFSLREDELLC-----RANHDLLERASA 151
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Medaka
Match: lhx9 (LIM homeobox 9 [Source:NCBI gene;Acc:100049461]) HSP 1 Score: 123.25 bits (308), Expect = 3.497e-30 Identity = 55/119 (46.22%), Postives = 76/119 (63.87%), Query Frame = 2
Query: 176 SLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLF-LQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVIC-LH 526
+LC GCGG I+D++ L + D +WH RCL+C +C L+ + TCF KDG YCKEDY + F +Q CA C+ G+ S+ V+ +YH+SC C CN+ L TGD F M+ + V C LH
Sbjct: 71 ALCAGCGGKISDRYYL-LAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCTTCNKTLTTGDHFGMKDSLVYCRLH 188 HSP 2 Score: 63.1586 bits (152), Expect = 3.144e-10 Identity = 32/78 (41.03%), Postives = 47/78 (60.26%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGID 1243
QKT R+RT QL T+++ +A N PDA +QL + TGL+ RV++VWFQN R K ++ + Q+ GG+D
Sbjct: 268 QKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNVL-------RQENGGVD 338
BLAST of insulin gene enhancer protein isl-1 vs. Planmine SMEST
Match: SMESG000059633.1 (SMESG000059633.1) HSP 1 Score: 959.903 bits (2480), Expect = 0.000e+0 Identity = 517/517 (100.00%), Postives = 517/517 (100.00%), Query Frame = 2
Query: 101 MTASLELEDCDDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSASILTRTERLPQSHQPASPLKQPKQELETESLMKIEDETNSRKSGCCRNYLEVVSDERLLMDTINNNTSGNISRANSRLSYVKGXXXXXXXXXXXXXXXXXXXXVCGNQSINGGHGGTIXXXXXXXXXXXXVTCTGNVKLSGTKRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLISAYHHLSRNGXXXXXXXXXXXXXXXXXQPLSNSNHPNLSFLTAMGLLSGARNGDLDDSPHDSFVGKLISYSVD 1651
MTASLELEDCDDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSASILTRTERLPQSHQPASPLKQPKQELETESLMKIEDETNSRKSGCCRNYLEVVSDERLLMDTINNNTSGNISRANSRLSYVKGILDDSSMNSDIDDISQDGSSVCGNQSINGGHGGTISAAGSLPSSGGGVTCTGNVKLSGTKRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLISAYHHLSRNGPCPPPPLMSLSHSPAHSQPLSNSNHPNLSFLTAMGLLSGARNGDLDDSPHDSFVGKLISYSVD
Sbjct: 1 MTASLELEDCDDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVICLHDHQRDGHLFLENSASILTRTERLPQSHQPASPLKQPKQELETESLMKIEDETNSRKSGCCRNYLEVVSDERLLMDTINNNTSGNISRANSRLSYVKGILDDSSMNSDIDDISQDGSSVCGNQSINGGHGGTISAAGSLPSSGGGVTCTGNVKLSGTKRSKEQKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEPPISCANPLEIQQIPGPWGSEEFGPNFSHGDISRSNDSAPAFQQLISAYHHLSRNGPCPPPPLMSLSHSPAHSQPLSNSNHPNLSFLTAMGLLSGARNGDLDDSPHDSFVGKLISYSVD 517
BLAST of insulin gene enhancer protein isl-1 vs. Planmine SMEST
Match: SMESG000029651.1 (SMESG000029651.1) HSP 1 Score: 96.2857 bits (238), Expect = 2.939e-21 Identity = 50/96 (52.08%), Postives = 69/96 (71.88%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEP 1297
+K R RTVL+EKQL TL+T Y NP+PDAL KEQL+E+TGL RVI VWFQNKRCK+KKR+I +++++++ G + + M+ SP+ EP
Sbjct: 224 KKAPRNRTVLSEKQLSTLQTFYQMNPKPDALTKEQLMEVTGLKQRVISVWFQNKRCKEKKRRI-SEELNKNKLPGMLS---KAELMLTESPVEYEP 315 HSP 2 Score: 89.7373 bits (221), Expect = 4.463e-19 Identity = 40/120 (33.33%), Postives = 65/120 (54.17%), Query Frame = 2
Query: 164 IKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIY-HISCMKCVACNRVLQTGDEFAMRPNGVIC 520
IK +C C G I + ++++PD+ H CLRC +C L ++CF+K G+ +C Y+ LFL++C C +D+VL Y H C+ C AC + L +G ++++ VIC
Sbjct: 5 IKENPICRVCNGFIQGQLSVKIEPDIPVHENCLRCYQCRTSLVYDDSCFIKFGRIFCHSHYRALFLKICRICYGSFVNTDFVLPFSRHDYCHAQCLNCTACRKPLTSGCKYSICEFSVIC 124
BLAST of insulin gene enhancer protein isl-1 vs. Planmine SMEST
Match: SMESG000029651.1 (SMESG000029651.1) HSP 1 Score: 96.2857 bits (238), Expect = 3.244e-21 Identity = 50/96 (52.08%), Postives = 69/96 (71.88%), Query Frame = 2
Query: 1010 QKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRQIMVKQMDQHQQVGGIDCPLQGVPMVAGSPMRNEP 1297
+K R RTVL+EKQL TL+T Y NP+PDAL KEQL+E+TGL RVI VWFQNKRCK+KKR+I +++++++ G + + M+ SP+ EP
Sbjct: 240 KKAPRNRTVLSEKQLSTLQTFYQMNPKPDALTKEQLMEVTGLKQRVISVWFQNKRCKEKKRRI-SEELNKNKLPGMLS---KAELMLTESPVEYEP 331 HSP 2 Score: 89.7373 bits (221), Expect = 5.893e-19 Identity = 40/120 (33.33%), Postives = 65/120 (54.17%), Query Frame = 2
Query: 164 IKSCSLCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQVCAACNRGLHKSDYVLHVGSRIY-HISCMKCVACNRVLQTGDEFAMRPNGVIC 520
IK +C C G I + ++++PD+ H CLRC +C L ++CF+K G+ +C Y+ LFL++C C +D+VL Y H C+ C AC + L +G ++++ VIC
Sbjct: 21 IKENPICRVCNGFIQGQLSVKIEPDIPVHENCLRCYQCRTSLVYDDSCFIKFGRIFCHSHYRALFLKICRICYGSFVNTDFVLPFSRHDYCHAQCLNCTACRKPLTSGCKYSICEFSVIC 140
BLAST of insulin gene enhancer protein isl-1 vs. Planmine SMEST
Match: SMESG000010916.1 (SMESG000010916.1) HSP 1 Score: 95.1301 bits (235), Expect = 1.308e-20 Identity = 42/108 (38.89%), Postives = 62/108 (57.41%), Query Frame = 2
Query: 182 CVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLF-LQVCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMR 502
C GC ITD+F L+ D WH CLRC C+ L + +CF +DG YCKEDY +LF + C C + + V+ V + ++H++C CV C R+L G+ F ++
Sbjct: 31 CAGCKSKITDRFFLKA-ADKMWHVNCLRCWICHVELHSEMSCFTRDGVVYCKEDYSRLFGRKCCIRCGVKITYDELVMRVKNLVFHVTCFCCVQCGRMLNPGEYFGLK 137 HSP 2 Score: 54.6842 bits (130), Expect = 1.209e-7 Identity = 25/59 (42.37%), Postives = 36/59 (61.02%), Query Frame = 2
Query: 1013 KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 1189
+ R+RT QL +++ +A N PDA + L E TGLS RV++VWFQN R K ++
Sbjct: 234 RQKRMRTSFKHHQLRAMKSYFALNHNPDAKDLKSLSEKTGLSKRVLQVWFQNARAKYRR 292
BLAST of insulin gene enhancer protein isl-1 vs. Planmine SMEST
Match: SMESG000001774.1 (SMESG000001774.1) HSP 1 Score: 92.8189 bits (229), Expect = 1.519e-20 Identity = 50/162 (30.86%), Postives = 80/162 (49.38%), Query Frame = 2
Query: 179 LCVGCGGAITDKFILRVQPDLEWHARCLRCVKCNRGLDEKNTCFVKDGKTYCKEDYQKLFLQ-VCAACNRGLHKSDYVLHVGSRIYHISCMKCVACNRVLQTGDEFAMRPNGVIC------------LHDHQRDGHLFLENSASILTRTERLPQSHQPASPL 625
LC GC ITDK+ LR + WH CL+C C + LD+ N+C+ ++G YC+ DY +++ Q CA C + + V+ V + ++HI C C C + L +G+ F + N + C Q D L L+N+ S+ E + +P P+
Sbjct: 11 LCSGCECVITDKYYLRTDEHV-WHGSCLKCDICEQSLDKTNSCYKRNGTFYCQHDYFRIYQQRKCAKCQEHIEHKEMVMKVLNSVFHIHCFICGVCGKRLNSGEYFLLNGNILFCQDEIRKSSISTIFSGIQSDFRLGLQNNQSLF---ESIFSKSKPRRPI 168 HSP 2 Score: 53.5286 bits (127), Expect = 1.732e-7 Identity = 25/59 (42.37%), Postives = 35/59 (59.32%), Query Frame = 2
Query: 1013 KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 1189
K R+RT Q+ +RT ++ N PD + L E TGLS RV++VWFQN R K ++
Sbjct: 193 KQKRLRTSFKHHQVRVMRTYFSLNHNPDTKDLKTLSEKTGLSKRVLQVWFQNARAKFRR 251 The following BLAST results are available for this feature:
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of insulin gene enhancer protein isl-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of insulin gene enhancer protein isl-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of insulin gene enhancer protein isl-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of insulin gene enhancer protein isl-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002801 ID=SMED30002801|Name=insulin gene enhancer protein isl-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1760bpback to top protein sequence of SMED30002801-orf-1 >SMED30002801-orf-1 ID=SMED30002801-orf-1|Name=SMED30002801-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=518bp MTASLELEDCDDGFRSNSKRSIKSCSLCVGCGGAITDKFILRVQPDLEWHback to top Aliases
The feature 'insulin gene enhancer protein isl-1' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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