TNF receptor-associated factor
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002783 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 196.052 bits (497), Expect = 4.008e-53 Identity = 147/458 (32.10%), Postives = 232/458 (50.66%), Query Frame = 1
Query: 1324 VTEQGF---QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSH-RNECLFVIVEC--DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEIL--PLIHNNIHHRDLCVKYL--SLCPYKCGMKEEISLVEHR--KICFSKPFLCPYIEV--GCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
V EQG +F+K V Y C C VL P QT CG R+C SC+ LS SS C C+ +++ + D R I AL++ C ++ C L ++ H +N+C F + C C +K R L H + C+ R+ C C P+ L L+ N ++ ++ L +C ++ ++ + ++ + KI + + E D N ++ + L +R+ +ES + + Q R T L+ ++ D++ S H +L + ++ + +T NG IW I+++ K+EA G+ S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF IMRGEYD +L WPF+ KVTL ++DQ S + H ++F+PD F KPT + N+ASG P F+ + LEN YI ++ F+K+ V
Sbjct: 33 VPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTA---CQESIVK--DKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELES-VDKSAGQVARNTGLLESQLS-RHDQMLSVHDIRL------ADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 477
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 187.578 bits (475), Expect = 9.670e-50 Identity = 152/510 (29.80%), Postives = 241/510 (47.25%), Query Frame = 1
Query: 1324 VTEQGF---QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSH-RNECLFVIVEC--DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPL----------------------EILPLIHNN-------IHHRDLCVKYLSLCP-YKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERN---LINHFSCLID-RLYLMESCLGELQ--SQAHRETDSLKKLI-----------------------TFDFDKVYSRHLSQLQILS-ETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
V EQG +F+K V Y C C VL P QT CG R+C SC+ LS SS C C+ +++ + D R I AL++ C ++ C L ++ H +N+C F + C C +K R L H + C+ R+ C C P+ + L+ + H V++++L + +++++SL+++ + +K + ++ C + ++ K M RN I H +ID + ++ E++ Q E DS+K + T + SRH L + + ++ + +T NG IW I+++ K+EA G+ S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF IMRGEYD +L WPF+ KVTL ++DQ S + H ++F+PD F KPT + N+ASG P F+ + LEN YI ++ F+K+ V
Sbjct: 33 VPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTA---CQESIVK--DKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQI-CSF-EIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 535
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 187.578 bits (475), Expect = 9.670e-50 Identity = 152/510 (29.80%), Postives = 241/510 (47.25%), Query Frame = 1
Query: 1324 VTEQGF---QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSH-RNECLFVIVEC--DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPL----------------------EILPLIHNN-------IHHRDLCVKYLSLCP-YKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERN---LINHFSCLID-RLYLMESCLGELQ--SQAHRETDSLKKLI-----------------------TFDFDKVYSRHLSQLQILS-ETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
V EQG +F+K V Y C C VL P QT CG R+C SC+ LS SS C C+ +++ + D R I AL++ C ++ C L ++ H +N+C F + C C +K R L H + C+ R+ C C P+ + L+ + H V++++L + +++++SL+++ + +K + ++ C + ++ K M RN I H +ID + ++ E++ Q E DS+K + T + SRH L + + ++ + +T NG IW I+++ K+EA G+ S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF IMRGEYD +L WPF+ KVTL ++DQ S + H ++F+PD F KPT + N+ASG P F+ + LEN YI ++ F+K+ V
Sbjct: 33 VPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTA---CQESIVK--DKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQI-CSF-EIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 535
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF2 (TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032]) HSP 1 Score: 180.644 bits (457), Expect = 9.980e-48 Identity = 149/498 (29.92%), Postives = 226/498 (45.38%), Query Frame = 1
Query: 1321 EVTEQGFQ---FLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEME-------TNIRTDAAASRFIKALKVKCTTKDCEYITTLENINS-HRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIH-HRDLCVKYLSLCPYKCGMKE--EISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRET----DSL-KKLITF---------------------------DFDKV--YSRHLSQLQILSETKNQSVKCTLDDTVFK------NGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLE---NYIVNNGFFLKISV 2643
E+ + GF K+ + Y C C+NVL P Q CG RYC C+ LS C C +E + E ++ D AA R +++L C + C + TL+ S H C ++ EC C H + EC +R C+ C P ++ H ++C K+ C CG K+ +H K C C + +GC +H + L H + L+ + + LG+ QS A E +SL KK TF D DK+ S + QL+ K+ ++ L+ V + +G +IW I +F+ ++EA AGR +I S FYT +GYK+C++IY NGDG G+ THLS+FF +M+G D +L WPF KVTL +LDQ + + H ++F+PD+ F +P D N+ASG P F S +E +Y+ ++ F+K V
Sbjct: 13 ELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAA---CVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRA-------PCCGADVKAHHEVCPKFPLTCD-GCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGD-QSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMA-DLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ-NNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 496
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 166.392 bits (420), Expect = 1.881e-42 Identity = 75/151 (49.67%), Postives = 103/151 (68.21%), Query Frame = 1
Query: 2197 DTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
+T NG IW I+++ K+EA G+ S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF IMRGEYD +L WPF+ KVTL ++DQ S + H ++F+PD F KPT + N+ASG P F+ + LEN YI ++ F+K+ V
Sbjct: 410 ETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 560 HSP 2 Score: 68.9366 bits (167), Expect = 4.208e-11 Identity = 72/269 (26.77%), Postives = 117/269 (43.49%), Query Frame = 1
Query: 1324 VTEQGF---QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSH-RNECLFVIVEC--DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEI--SLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKL 2100
V EQG +F+K V Y C C VL P QT CG R+C SC+ LS SS C C+ ++ + + D R I AL++ C ++ C L ++ H +N+C F + C C +K R L H + C+ R+ C C +P+I H C + CP+KC ++ + L H C + P C + GC + + H + + H + L + +E + LQ+++ + S++ L
Sbjct: 33 VPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCT---ACQESIV--KDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQ-----VPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSL 291
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80]) HSP 1 Score: 137.502 bits (345), Expect = 7.684e-34 Identity = 109/453 (24.06%), Postives = 199/453 (43.93%), Query Frame = 1
Query: 1324 VTEQGFQFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCT--TKDCEYITTLENINSHRNECLF-VIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGM--KEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKL--CMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISK-KNHYSESFQPDIKLIC-----FHKPTADFNVASGSPKFITFSNLENYIVNNGFFLKISV 2643
+T Q F +P+ C IC+ L DP++ +C YCR C E+ + + C + EL + D A + I AL V CT + C + L ++ H +EC F ++C++C ++F +N L H+ R FC + + H C + + CP++CG+ + + + H C + +CP++ GC + + +H+ + H L D + ++ T L + F+ +R LS + +E IW I + EAK+G +I S PF + FGYK+ C ++ +G GK +S++ +++GE+DP L WPF + +S+LDQ + ++ + ++ D + + +P + N A GS F + + L+NY+ ++ +++I V
Sbjct: 1 MTSQSVMFKGGLPADCTCPICEQALRDPIKLNCDHHYCRQCF-ENENRTPGCAACQTIIQPELCQH------DRAKQKQILALPVVCTFESSGCPWDGQLGTLHDHLSECTFKSSLKCEKCGRQFAKNDLEKHRAKCELNRAVCS-FCNKTI------RDSDRERHPKTCPQVIISCPFQCGLTDRPRLEIEAHCPSCPNVDNVCPFVPYGCTFAGGKESIQQHLSDEPVRHLMYLCDEITDLKG------------TYELMERDMGSFNDRQTRILSAAETCTE--------------MFGPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKS--ISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPRPEDRVNITYVIDPRKLKANEKFLARPRGERNAAFGSQSFCSLAILQNYVKDDKIYVQIDV 411
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-2 (TNF Receptor Associated Factor (TRAF) homolog [Source:UniProtKB/TrEMBL;Acc:Q9N586]) HSP 1 Score: 71.2478 bits (173), Expect = 1.203e-12 Identity = 43/124 (34.68%), Postives = 64/124 (51.61%), Query Frame = 1
Query: 2284 SICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESF----QPDIKLICFHKPTADFNVASGSPKFITFSNLENYIVNNGFFLKISV 2643
SI S PFY+ +GYK+ P GDGL + + SVF +M+GE+D IL WPFR VT SIL KK +++ P+I+ +P N G F+ + + + + F++I V
Sbjct: 182 SIYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSILSD-DKKELLTKTIYVNEMPEIQEF-LERPEGLRNGTFGFQNFLPLAKVTEFAADGDIFIQIKV 303
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0334401) HSP 1 Score: 121.709 bits (304), Expect = 2.112e-28 Identity = 97/358 (27.09%), Postives = 156/358 (43.58%), Query Frame = 1
Query: 1597 CEYITTLENINSHRNECLFVIVECD-QCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKC--GMKEEISLVEH-RKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQ--ISKKNHYSESFQPDIKLICFHKPTADFN-VASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
C+ + + H C V C+ +C ++ R + HK +C KR C C F + LPL H C + CP +C G L H R C S C + E GC + L H+E N H S ++ + SR Q+Q+L K+ K +++ T G +W I ++S EA+ + S PFYT ++GYKL ++ NG+G G+ TH+SV+ ++ GEYD +L WPF + +T ++ +Q S + +ESF PD F +P+ + + + G P+FI+ L + +I + FL++ V
Sbjct: 158 CQSEFSGAGLEEHNGSCGQEPVYCEAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQREFSADTLPL------HAAQCPRAPLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSLMV---------------------------------ALSSRQGQQIQML---KSAVSKLSINYT----GTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRPFIKGDTVFLRVKV 469
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0077429) HSP 1 Score: 121.324 bits (303), Expect = 2.607e-28 Identity = 97/358 (27.09%), Postives = 156/358 (43.58%), Query Frame = 1
Query: 1597 CEYITTLENINSHRNECLFVIVECD-QCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKC--GMKEEISLVEH-RKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQ--ISKKNHYSESFQPDIKLICFHKPTADFN-VASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
C+ + + H C V C+ +C ++ R + HK +C KR C C F + LPL H C + CP +C G L H R C S C + E GC + L H+E N H S ++ + SR Q+Q+L K+ K +++ T G +W I ++S EA+ + S PFYT ++GYKL ++ NG+G G+ TH+SV+ ++ GEYD +L WPF + +T ++ +Q S + +ESF PD F +P+ + + + G P+FI+ L + +I + FL++ V
Sbjct: 167 CQSEFSGAGLEEHNGSCGQEPVYCEAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQREFSADTLPL------HAAQCPRAPLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSLMV---------------------------------ALSSRQGQQIQML---KSAVSKLSINYT----GTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRPFIKGDTVFLRVKV 478
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0308606) HSP 1 Score: 68.9366 bits (167), Expect = 1.401e-11 Identity = 47/150 (31.33%), Postives = 71/150 (47.33%), Query Frame = 1
Query: 2215 GNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQ---ISKKNHYSESFQPDIKLICFHKPTADFNVASGS----PKFITFSNLENYIVNNGFFLKISV 2643
G+ IW IK++S EE+K + S F FGY L + IY NG G K ++ ++ GEYDP+L WP R + + I DQ ++ Y +K I K + DF + S P + S NY+ N+ F+++ V
Sbjct: 255 GHLIWRIKDYSKKLEESKQY-DTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVADAEDY-------VKTIFVRKKSDDF-IQSNQYFHIPHKVITS--RNYLRNDSMFIEVRV 393
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0074274) HSP 1 Score: 68.9366 bits (167), Expect = 1.401e-11 Identity = 47/150 (31.33%), Postives = 71/150 (47.33%), Query Frame = 1
Query: 2215 GNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQ---ISKKNHYSESFQPDIKLICFHKPTADFNVASGS----PKFITFSNLENYIVNNGFFLKISV 2643
G+ IW IK++S EE+K + S F FGY L + IY NG G K ++ ++ GEYDP+L WP R + + I DQ ++ Y +K I K + DF + S P + S NY+ N+ F+++ V
Sbjct: 255 GHLIWRIKDYSKKLEESKQY-DTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVADAEDY-------VKTIFVRKKSDDF-IQSNQYFHIPHKVITS--RNYLRNDSMFIEVRV 393
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0334036) HSP 1 Score: 68.9366 bits (167), Expect = 1.401e-11 Identity = 47/150 (31.33%), Postives = 71/150 (47.33%), Query Frame = 1
Query: 2215 GNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQ---ISKKNHYSESFQPDIKLICFHKPTADFNVASGS----PKFITFSNLENYIVNNGFFLKISV 2643
G+ IW IK++S EE+K + S F FGY L + IY NG G K ++ ++ GEYDP+L WP R + + I DQ ++ Y +K I K + DF + S P + S NY+ N+ F+++ V
Sbjct: 255 GHLIWRIKDYSKKLEESKQY-DTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVADAEDY-------VKTIFVRKKSDDF-IQSNQYFHIPHKVITS--RNYLRNDSMFIEVRV 393
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 188.348 bits (477), Expect = 2.922e-50 Identity = 149/529 (28.17%), Postives = 242/529 (45.75%), Query Frame = 1
Query: 1288 SLNSKLYNCHPEVTEQGFQFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNE-LLEMETNIRT------DAAASRFIKALKVKCTTKDCEYITTLENI-NSHRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKE--EISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFS---CLIDRLYLMESCLGELQ----------------SQAH-----------RETDSLKKLI---------------------TFDFDKV--YSRHLSQLQILSETKN-------QSVK----CTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNL---ENYIVNNGFFLKISV 2643
SL S L + P ++ + + Y C CK++L P Q CG R+C C + S C E CR E + E ET++ D AA R I +L KC + C + TL++ N H C F V+C+ C + H + ECE R C++C ++F + + H ++C K+ C CG K+ EH K C C + E+GC + +H + +++ H L+ + L GE Q + AH ++ +L+ ++ D +K+ S + QL+ T++ QS++ CT D G +IW I EFS +++A AGR ++ S FY+ ++GYK+C+++Y NGDG G+ +HLS+FF +M+G+YD +L WPF KVTL +LDQ + + H ++F+PD+ F +P ++ N+ASG P F + L +Y+ ++ F+K V
Sbjct: 18 SLPSSLDSTLPGISREVLSV--SMEPKYQCQQCKDILRKPFQAQCGHRFCVFCFKQLTSSGPIPC---EACRAEGIFEEETSVLNIAVAFPDNAARREIDSLPAKCPNEGCSWSGTLKDFENQHEGRCAFERVKCEACQVLILLSEKDRHNERECEARTLNCKYCKVTFNFKEIKA------HDEICQKFPMQC-KDCGKKKIPREKFQEHTKSCAKSKSACQFREIGCRAVVDNCKQQEHEQTSIMEHLRLMLALLSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVERSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYD------GVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQ-NNREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIV 527
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 188.348 bits (477), Expect = 2.922e-50 Identity = 149/529 (28.17%), Postives = 242/529 (45.75%), Query Frame = 1
Query: 1288 SLNSKLYNCHPEVTEQGFQFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNE-LLEMETNIRT------DAAASRFIKALKVKCTTKDCEYITTLENI-NSHRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKE--EISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFS---CLIDRLYLMESCLGELQ----------------SQAH-----------RETDSLKKLI---------------------TFDFDKV--YSRHLSQLQILSETKN-------QSVK----CTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNL---ENYIVNNGFFLKISV 2643
SL S L + P ++ + + Y C CK++L P Q CG R+C C + S C E CR E + E ET++ D AA R I +L KC + C + TL++ N H C F V+C+ C + H + ECE R C++C ++F + + H ++C K+ C CG K+ EH K C C + E+GC + +H + +++ H L+ + L GE Q + AH ++ +L+ ++ D +K+ S + QL+ T++ QS++ CT D G +IW I EFS +++A AGR ++ S FY+ ++GYK+C+++Y NGDG G+ +HLS+FF +M+G+YD +L WPF KVTL +LDQ + + H ++F+PD+ F +P ++ N+ASG P F + L +Y+ ++ F+K V
Sbjct: 18 SLPSSLDSTLPGISREVLSV--SMEPKYQCQQCKDILRKPFQAQCGHRFCVFCFKQLTSSGPIPC---EACRAEGIFEEETSVLNIAVAFPDNAARREIDSLPAKCPNEGCSWSGTLKDFENQHEGRCAFERVKCEACQVLILLSEKDRHNERECEARTLNCKYCKVTFNFKEIKA------HDEICQKFPMQC-KDCGKKKIPREKFQEHTKSCAKSKSACQFREIGCRAVVDNCKQQEHEQTSIMEHLRLMLALLSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVERSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYD------GVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQ-NNREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIV 527
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 188.348 bits (477), Expect = 3.856e-50 Identity = 149/529 (28.17%), Postives = 242/529 (45.75%), Query Frame = 1
Query: 1288 SLNSKLYNCHPEVTEQGFQFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNE-LLEMETNIRT------DAAASRFIKALKVKCTTKDCEYITTLENI-NSHRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKE--EISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFS---CLIDRLYLMESCLGELQ----------------SQAH-----------RETDSLKKLI---------------------TFDFDKV--YSRHLSQLQILSETKN-------QSVK----CTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNL---ENYIVNNGFFLKISV 2643
SL S L + P ++ + + Y C CK++L P Q CG R+C C + S C E CR E + E ET++ D AA R I +L KC + C + TL++ N H C F V+C+ C + H + ECE R C++C ++F + + H ++C K+ C CG K+ EH K C C + E+GC + +H + +++ H L+ + L GE Q + AH ++ +L+ ++ D +K+ S + QL+ T++ QS++ CT D G +IW I EFS +++A AGR ++ S FY+ ++GYK+C+++Y NGDG G+ +HLS+FF +M+G+YD +L WPF KVTL +LDQ + + H ++F+PD+ F +P ++ N+ASG P F + L +Y+ ++ F+K V
Sbjct: 31 SLPSSLDSTLPGISREVLSV--SMEPKYQCQQCKDILRKPFQAQCGHRFCVFCFKQLTSSGPIPC---EACRAEGIFEEETSVLNIAVAFPDNAARREIDSLPAKCPNEGCSWSGTLKDFENQHEGRCAFERVKCEACQVLILLSEKDRHNERECEARTLNCKYCKVTFNFKEIKA------HDEICQKFPMQC-KDCGKKKIPREKFQEHTKSCAKSKSACQFREIGCRAVVDNCKQQEHEQTSIMEHLRLMLALLSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVERSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYD------GVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQ-NNREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIV 540
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 167.162 bits (422), Expect = 1.358e-43 Identity = 141/502 (28.09%), Postives = 223/502 (44.42%), Query Frame = 1
Query: 1339 FQFLKKVPSAYFCVICKNVLTDPVQTS-CGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSHRNECLFVIVEC-DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISF----------------------------------------PLEILP-------LIHNNIH-HRDLCVKYLSLCPYKCGMK--EEISLVEH-RKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQ----ISKKNHYSESFQPDIKLICFHKPTADFN------VASGSPKFITFSNLE--NYIVNNGFFLKISV 2643
++FL+K + C +C + +PVQ S CG R+C +C+ E LS + C + ++L I D + I AL ++C + + C + ++ + SH + C F ++ C ++CS K TR L H + +C KRK C+FCG F P P +++ I H+ C ++ CP +CG L H ++ C S LCP+ E GC + + + +H+E + +H L +M S +G R+ + +L R + +L +V +G IW + ++S +EAK S PFYT +GYKL + + NG+G G+ +HLS++ ++ GEYD +L WPF KVT SILDQ +SK H +E+F PD F KP + N + G PKFI+ ++ NYI +N FLK S+
Sbjct: 6 YKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPE-----DQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCPNRCSVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAYENHQGICPQESVYCENKCGARMMRRLLSQHTMTECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLANHVKESCGSALVLCPFKEAGCKHRCPKMAIGRHLEESTKSH-------LTMMCSLVG-------RQRQEILEL---------RREMEEL-----------------SVSHDGVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSSRNSLDESTLGFGYPKFISHEEIKKRNYIRDNSIFLKASI 462
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 167.162 bits (422), Expect = 1.358e-43 Identity = 141/502 (28.09%), Postives = 223/502 (44.42%), Query Frame = 1
Query: 1339 FQFLKKVPSAYFCVICKNVLTDPVQTS-CGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSHRNECLFVIVEC-DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISF----------------------------------------PLEILP-------LIHNNIH-HRDLCVKYLSLCPYKCGMK--EEISLVEH-RKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQ----ISKKNHYSESFQPDIKLICFHKPTADFN------VASGSPKFITFSNLE--NYIVNNGFFLKISV 2643
++FL+K + C +C + +PVQ S CG R+C +C+ E LS + C + ++L I D + I AL ++C + + C + ++ + SH + C F ++ C ++CS K TR L H + +C KRK C+FCG F P P +++ I H+ C ++ CP +CG L H ++ C S LCP+ E GC + + + +H+E + +H L +M S +G R+ + +L R + +L +V +G IW + ++S +EAK S PFYT +GYKL + + NG+G G+ +HLS++ ++ GEYD +L WPF KVT SILDQ +SK H +E+F PD F KP + N + G PKFI+ ++ NYI +N FLK S+
Sbjct: 6 YKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPE-----DQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCPNRCSVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAYENHQGICPQESVYCENKCGARMMRRLLSQHTMTECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLANHVKESCGSALVLCPFKEAGCKHRCPKMAIGRHLEESTKSH-------LTMMCSLVG-------RQRQEILEL---------RREMEEL-----------------SVSHDGVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSSRNSLDESTLGFGYPKFISHEEIKKRNYIRDNSIFLKASI 462
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 202.601 bits (514), Expect = 7.336e-55 Identity = 163/535 (30.47%), Postives = 257/535 (48.04%), Query Frame = 1
Query: 1279 PFQSLNSKLYNCHPEVTEQGF---QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSH-RNECLFVIVECDQ--CSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMK---------------EEISLVEHRKICFSKPFLCPYIEVGCDYL-------------------FFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQS---------QAHRETDSLKKLITFDFDKVYSRHLSQLQILS-----------ETK----------------NQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
P +SL + +Y V EQG +FLK V Y C C+ VL +P QT CG R+C +C+ LS +S C ED + + D R + AL++ C T+ C+ + TL N+ H +++C F + C + C +K R L H + C+ R+ C+FC +PL+ H C + CP+ C +K E S V+H + K + Y+E L F +++ +H E+ L N+ + +I ++E +L+ Q E D +K +++ + +R LSQL++++ ET+ + ++ + +T NG IW I+++ K+EA G+ S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF IMRGEYD +L WPF+ KV+L ++DQ + H ++F+PD F KPT + N+ASG P F+ + LEN YI ++ F+K+ V
Sbjct: 18 PDRSLATTIY-----VPEQGGYKERFLKPVEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNITK-----DKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFC-----RNQVPLVEMQKHEDVDCPSVVISCPHMCSVKSLLRSEGTNQQIKAHEASSAVQH--VNLMKEW-SNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQ-LRNNEARIIQLQRVIEGQADKLKDLDKEIRNLRQTGDEADGMKS----NYESLQNR-LSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 528
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: sytl2 (synaptotagmin like 2 [Source:Xenbase;Acc:XB-GENE-945155]) HSP 1 Score: 171.4 bits (433), Expect = 7.373e-45 Identity = 143/504 (28.37%), Postives = 225/504 (44.64%), Query Frame = 1
Query: 1339 FQFLKKVPSAYFCVICKNVLTDPVQTS-CGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSHRNECLFVIVEC-DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISF----------------------------------------PLEILPLIHNNIH--------HRDLCVKYLSLCPYKCGM----KEEISLVEHRK-ICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQ----ISKKNHYSESFQPDIKLICFHKPTADFN------VASGSPKFITFSNL--ENYIVNNGFFLKISV 2643
++FL+K+ + C +C + +PVQ S CG R+C +C+ E LS + C + ++L I D + L ++C + + C + L+ + H N C F ++ C ++CS K R L H + +C KRK C+FCG F P P + N H+ C +Y + CP +CG+ +E++S H K C S LCP+ + GC + + +++H+E N+ H S +M S L S+ +E L+K + +L + SE G IW I ++S +EAK S PFYT ++GYKL + + NG+G G+ ++LSV+ ++ GEYD +L WPF +VT S+LDQ +SK H +E+F PD F KPT N + G PKFI+ ++ NY+ +N FL+ SV
Sbjct: 6 YKFLEKLRRKFLCPLCGKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPE-----DQLPLDYAKIYPDRDLETQVMGLSIRCIHSEEGCRWSGQLKQLQPHLNICAFNVIPCPNRCSTKLIRRDLPEHMQHDCPKRKVRCEFCGADFTGEAYEDHQGCCPQESVYCENKCGARMMRRVLSQHSLVECPKRTQPCPYCNKEFVFDTIQSHQYQCPRYPTPCPNQCGIASIAREDLS--NHLKDSCSSALVLCPFKDSGCKHRGPKITISRHLEENMRAHLS-------MMSS----LVSRQRQEILELRK------------QVEELSVSSE-----------------GVLIWKISDYSRKVQEAKVRGNFESFSPPFYTHKYGYKLQVSAFLNGNGSGEGSYLSVYIRVLPGEYDNLLEWPFSYRVTFSLLDQSDPSLSKPQHITETFNPDPNWKNFQKPTGSRNSLDESTLGFGYPKFISHEDIRKRNYVRDNAIFLRASV 462
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925]) HSP 1 Score: 166.392 bits (420), Expect = 1.098e-42 Identity = 147/516 (28.49%), Postives = 227/516 (43.99%), Query Frame = 1
Query: 1324 VTEQGFQFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVE--HLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC-TTKDCEYITTLENINSHRNECLFVIVEC--DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIH-----NN----------------------------------IHHRDLCVKYLSLCPYKC-----GMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSET---------------KNQSVKCTLDDTVFK-------NGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN-----YIVNNGFFLKISV 2643
V +Q + F++++ Y C C VL +P QT CG R+C CI LS + C D E+ ++ I D R + L V C + C+ L H +CL+ + C D C + R L H + EC+ R+E C +C + L + L + NN + + L V +L LC + G+++ + L EH+ S + E C + F + + + ID+ +E + +L S+ H D L T + K + LS L+ + N ++ T ++ F+ NG IW I ++ K EA GR SI S FYT GY+LC + Y NGDG GK + LS++F +M+GE+D IL+WPF+ KVTL +LDQ KKNH ++ F+ D F +P ++ N+ASG P+F + + LEN YI ++ F+KI V
Sbjct: 27 VPKQEYLFVEQLQDRYKCASCHLVLHNPHQTGCGHRFCEKCISNLIELSETPQCPIDMENIKSH------EIFKDNCCKREVLNLLVYCKNSPACDVKVMLGRYQEHLGQCLYEMTLCSNDGCHDQMIRKELKGHLESECKLRQEACIYCKQTMSLCLACLDYMFSCRNNYKKIFFSFQLDKHLCECPEAELQCTFSNYGCNVMVLYHSLSVHFLYLCTFTSVSQVLGLQQNLDLKEHQIQQLSDTV--KWCEKEC-HQFGQFTGSNGNSLSSTKTLASYIDKSMWLEEQVIQLVSKEHSRLDLRPILDTLESTK---QRLSTLEAYKDRIDNLDGQFKKHDVLLSNHKMQMTSNEERFRLVEGTSYNGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRADPNSSSFKRPDSEMNIASGCPRFASHAQLENPKNGCYIKDDTLFIKIVV 530
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 163.31 bits (412), Expect = 1.921e-41 Identity = 73/151 (48.34%), Postives = 102/151 (67.55%), Query Frame = 1
Query: 2197 DTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
+T NG IW I+++ K+EA G+ S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF IMRGEYD +L WPF+ KV+L ++DQ + H ++F+PD F KPT + N+ASG P F+ + LEN YI ++ F+K+ V
Sbjct: 403 ETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 553 HSP 2 Score: 80.1073 bits (196), Expect = 1.230e-14 Identity = 81/305 (26.56%), Postives = 140/305 (45.90%), Query Frame = 1
Query: 1279 PFQSLNSKLYNCHPEVTEQGF---QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSH-RNECLFVIVECDQ--CSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEI--SLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLK----KLITFDFDKVYSRHLSQLQ 2151
P +SL + +Y V EQG +FLK V Y C C+ VL +P QT CG R+C +C+ LS +S C ED + + D R + AL++ C T+ C+ + TL N+ H +++C F + C + C +K R L H + C+ R+ C+FC +PL+ H C + CP+ C +K + L H C + P C + GC + + H + + H + + + +E+ + LQ+++ + S++ ++ +F+ + RH QL+
Sbjct: 18 PDRSLATTIY-----VPEQGGYKERFLKPVEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNIT-----KDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFC-----RNQVPLVEMQKHEDVDCPSVVISCPHMCSVKSLLRSELNAHLLECVNAPSTCSFKRYGCTFKGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIE--IERHKEQLR 305
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415]) HSP 1 Score: 158.688 bits (400), Expect = 1.866e-40 Identity = 134/489 (27.40%), Postives = 214/489 (43.76%), Query Frame = 1
Query: 1354 KVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMK----EEISLVE---HRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLY----------------------------------LMESCLGELQSQAHRET---DSLKKLITFDFDKVYS---------RHLSQLQILS---ETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLE---NYIVNNGFFLKISV 2643
K+ Y C CKN+L P+Q CG RYC C+ + + + + +C C D + L ++ H +C +++ C C H + EC +RK C++C +SF P I H ++C K+ C CG K E++ L R I S P C Y VGC + +H ++L H + + D + E+ + L + R + + L + + +KV + R L Q +++ ET+ Q + + D VF IW I EF +++A GR ++ S PFYT ++GYK+C++IY NGDG G+ THLS+FF +M+G D +L WPF KVTL +LDQ + + H ++F+PD+ F +P ++ N+ASG P F S LE +Y+ ++ F+K+ V
Sbjct: 30 KLEVKYLCSDCKNLLRRPLQAQCGHRYCSHCLNKIIRWVARNWGGVPEC------------------------PAVCERSD--WTGALISV-GHEGKCPYLLAPCPACKTIIRAANRDLHSERECPERKLNCRYCKLSF---YFPDIK---AHDEICPKFPMTC-EGCGRKKIPREKVRLFVCSFSRNITLSLP--CRYAAVGCTEMVENDKCLEHENKSLAEHLAKVWDYIQHGRKEQNDLSVRMGSLSVQGSPAPPFDTLDKKNTTFENIVSVLNREVERSSHAAEELARQLRAAQEKVEALTTKVRQLERTLGQKELIVAELETRMQESELSTYDGVF-----IWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQ-NNREHVIDAFRPDVSSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIV 476
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 186.808 bits (473), Expect = 6.375e-50 Identity = 145/496 (29.23%), Postives = 225/496 (45.36%), Query Frame = 1
Query: 1321 EVTEQGFQ---FLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEME-------TNIRTDAAASRFIKALKVKCTTKDCEYITTLENINS-HRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIH-HRDLCVKYLSLCPYKCGMKE--EISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQA------------------------HRETDSLK-------KLITFDFDKV--YSRHLSQLQILSETKNQSV-----KCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLE---NYIVNNGFFLKISV 2643
E+ + GF ++ + Y C CKN+L P Q CG RYC C+ LS C C E L E ++ D AA R +++L C C + TL+ S H C F++ EC C + H + EC KR CQ C P H ++ H ++C K+ C CG K+ + +H + C LC + VGC + T +L H + L H + L+ ++ G L +RE + + + D DK+ S + QL+ K+ ++ K + + +G +IW I +F+ ++EA AGR +I S FYT +GYK+C+++Y NGDG G+ THLS+FF +M+G D +L WPF KVTL +LD + + H ++F+PD+ F +P +D N+ASG P F S +E +Y+ ++ F+K V
Sbjct: 13 ELLQPGFSKTLLGTRLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNC---AACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRA-------PCSHVDLEVHYEVCPKFPLTCD-GCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDH-NNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 496
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 184.496 bits (467), Expect = 3.911e-49 Identity = 143/500 (28.60%), Postives = 225/500 (45.00%), Query Frame = 1
Query: 1321 EVTEQGFQ---FLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLS----FSSYCCNDSEDCRNELLEME-------TNIRTDAAASRFIKALKVKCTTKDCEYITTLENINS-HRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIH-HRDLCVKYLSLCPYKCGMKE--EISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQA----HRETDSLKKLITFD-FDKVYSRHLSQLQILSETKNQSVKCTLD---------------------------------DTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLE---NYIVNNGFFLKISV 2643
E+ + GF ++ + Y C CKN+L P Q CG RYC C+ L SS + C E L E ++ D AA R +++L C C + TL+ S H C F++ EC C + H + EC KR CQ C P H ++ H ++C K+ C CG K+ + +H + C LC + VGC + T +L H + L H + L+ ++ G L R +K+ TF+ V +R + ++ + +E ++ + D + +G +IW I +F+ ++EA AGR +I S FYT +GYK+C+++Y NGDG G+ THLS+FF +M+G D +L WPF KVTL +LD + + H ++F+PD+ F +P +D N+ASG P F S +E +Y+ ++ F+K V
Sbjct: 13 ELLQPGFSKTLLGTRLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILRCASILSSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRA-------PCSHVDLEVHYEVCPKFPLTCD-GCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDH-NNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 503
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 184.882 bits (468), Expect = 5.188e-49 Identity = 145/505 (28.71%), Postives = 232/505 (45.94%), Query Frame = 1
Query: 1324 VTEQGF---QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSED------------CRNELLEMETNIRTDAAA-------SRFIKALK-------VKCTTKDCEYITTLENINSH-RNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXX-XQFCGISFPLEILPLIHN-NIHHRDLCVKYLSLCP-YKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERN---LINHFSCLID-RLYLMESCLGELQ--SQAHRETDSLKKLI-----------------------TFDFDKVYSRHLSQLQILS-ETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
V EQG +F+K V Y C C+ VL +P QT CG R+C SC+ LS SS C ++ C+ E+L ++ R + + LK + C DC+ +++ H C + C C + L H+ +C C + L H V++++L + +++++SL+++ + +K + ++ C + ++ K M RN I H +ID + ++ E++ Q E DS+K + T + SRH L + + ++ + +T NG IW I+++ K+EA G+ S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF IMRGEYD +L WPF+ KVTL ++DQ S + H ++F+PD F KPT + N+ASG P F+ + LEN YI ++ F+K+ V
Sbjct: 32 VPEQGGYKEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQI-CSF-EIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 534
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 184.882 bits (468), Expect = 5.188e-49 Identity = 145/505 (28.71%), Postives = 232/505 (45.94%), Query Frame = 1
Query: 1324 VTEQGF---QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSED------------CRNELLEMETNIRTDAAA-------SRFIKALK-------VKCTTKDCEYITTLENINSH-RNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXX-XQFCGISFPLEILPLIHN-NIHHRDLCVKYLSLCP-YKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERN---LINHFSCLID-RLYLMESCLGELQ--SQAHRETDSLKKLI-----------------------TFDFDKVYSRHLSQLQILS-ETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
V EQG +F+K V Y C C+ VL +P QT CG R+C SC+ LS SS C ++ C+ E+L ++ R + + LK + C DC+ +++ H C + C C + L H+ +C C + L H V++++L + +++++SL+++ + +K + ++ C + ++ K M RN I H +ID + ++ E++ Q E DS+K + T + SRH L + + ++ + +T NG IW I+++ K+EA G+ S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF IMRGEYD +L WPF+ KVTL ++DQ S + H ++F+PD F KPT + N+ASG P F+ + LEN YI ++ F+K+ V
Sbjct: 32 VPEQGGYKEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQI-CSF-EIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 534
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548]) HSP 1 Score: 172.555 bits (436), Expect = 9.863e-45 Identity = 148/521 (28.41%), Postives = 232/521 (44.53%), Query Frame = 1
Query: 1339 FQFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCI--VEHLSFSSYCCNDSED-----------CRNELLEMETNIRTDAAAS------RFIKALK------VKCTTKDCEYITTLENINSHRNE-CLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFP---LEILPLIHNNIHHRDLCVKYLSLCPYK---CGMK-EEISLVEHRKICFSKPFLCP-----YIEVGCDYLFFTVDLNKHMER--NLINH-----------FSCL--------IDRLYLMESCLGEL----QSQAHR--------ETDSLKKLIT---------FDFDKVYSRHLSQLQILSE--TKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN----YIVNNGFFLKISV 2643
+QF++++ Y C C +VL +P QT CG R+C+ CI + L+ C D E C+ E+L + + + RF L+ V C + C +++ H + C F +C C + L H++ C +S P ++ +P N H +C + CP+K C +K + +L+EH + L +E + L +++ K M + I H FS L D+ +E+ + +L Q R DS+K+ IT + S+H + + I KN+ L+ + +G IW + ++ V K EA G S+ S PFYT GY+LC + Y NGDG GK THLS++F +MRGE+D +L WPFR +VTL +LDQ KKNH E+F+ D F +P + N+ASG P+F++ S LEN YI ++ FLK++V
Sbjct: 33 YQFVEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQEVFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVKEHLSAYCRFREEKCLYCKRDIVVTNLQDHEENSCPAYP-------VSCPNRCVQTIPRARVN-EHLTVCPEAEQDCPFKHYGCTVKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRVNALLSSLERKKKMAAADSAIQHATNPMSRFQDIFSFLYRKALTSHTDKSAWLEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRITQLEASDQRLVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACY-SGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAV 544
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P39429|TRAF2_MOUSE (TNF receptor-associated factor 2 OS=Mus musculus OX=10090 GN=Traf2 PE=1 SV=1) HSP 1 Score: 186.808 bits (473), Expect = 4.459e-49 Identity = 145/496 (29.23%), Postives = 225/496 (45.36%), Query Frame = 1
Query: 1321 EVTEQGFQ---FLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEME-------TNIRTDAAASRFIKALKVKCTTKDCEYITTLENINS-HRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIH-HRDLCVKYLSLCPYKCGMKE--EISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQA------------------------HRETDSLK-------KLITFDFDKV--YSRHLSQLQILSETKNQSV-----KCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLE---NYIVNNGFFLKISV 2643
E+ + GF ++ + Y C CKN+L P Q CG RYC C+ LS C C E L E ++ D AA R +++L C C + TL+ S H C F++ EC C + H + EC KR CQ C P H ++ H ++C K+ C CG K+ + +H + C LC + VGC + T +L H + L H + L+ ++ G L +RE + + + D DK+ S + QL+ K+ ++ K + + +G +IW I +F+ ++EA AGR +I S FYT +GYK+C+++Y NGDG G+ THLS+FF +M+G D +L WPF KVTL +LD + + H ++F+PD+ F +P +D N+ASG P F S +E +Y+ ++ F+K V
Sbjct: 13 ELLQPGFSKTLLGTRLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNC---AACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRA-------PCSHVDLEVHYEVCPKFPLTCD-GCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDH-NNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 496
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q12933|TRAF2_HUMAN (TNF receptor-associated factor 2 OS=Homo sapiens OX=9606 GN=TRAF2 PE=1 SV=2) HSP 1 Score: 180.644 bits (457), Expect = 4.793e-47 Identity = 149/498 (29.92%), Postives = 226/498 (45.38%), Query Frame = 1
Query: 1321 EVTEQGFQ---FLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEME-------TNIRTDAAASRFIKALKVKCTTKDCEYITTLENINS-HRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIH-HRDLCVKYLSLCPYKCGMKE--EISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRET----DSL-KKLITF---------------------------DFDKV--YSRHLSQLQILSETKNQSVKCTLDDTVFK------NGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLE---NYIVNNGFFLKISV 2643
E+ + GF K+ + Y C C+NVL P Q CG RYC C+ LS C C +E + E ++ D AA R +++L C + C + TL+ S H C ++ EC C H + EC +R C+ C P ++ H ++C K+ C CG K+ +H K C C + +GC +H + L H + L+ + + LG+ QS A E +SL KK TF D DK+ S + QL+ K+ ++ L+ V + +G +IW I +F+ ++EA AGR +I S FYT +GYK+C++IY NGDG G+ THLS+FF +M+G D +L WPF KVTL +LDQ + + H ++F+PD+ F +P D N+ASG P F S +E +Y+ ++ F+K V
Sbjct: 13 ELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAA---CVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRA-------PCCGADVKAHHEVCPKFPLTCD-GCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGD-QSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMA-DLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ-NNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 496
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q60803|TRAF3_MOUSE (TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN=Traf3 PE=1 SV=2) HSP 1 Score: 167.548 bits (423), Expect = 4.661e-42 Identity = 88/212 (41.51%), Postives = 131/212 (61.79%), Query Frame = 1
Query: 2014 LIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
L +R+ +ES + + QA R T L+ ++ D++ S H +L + ++ + +T NG IW I+++ K+EA G+ S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF IMRGEYD +L WPF+ KVTL ++DQ S + H ++F+PD F KPT + N+ASG P F+ + LEN YI ++ F+K+ V
Sbjct: 356 LQNRVTELES-VDKSAGQAARNTGLLESQLS-RHDQMLSVHDIRL------ADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 559 HSP 2 Score: 75.0998 bits (183), Expect = 2.648e-12 Identity = 75/269 (27.88%), Postives = 119/269 (44.24%), Query Frame = 1
Query: 1324 VTEQGF---QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTT--KDCEYITTLENINSH-RNECLFVIVEC--DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEI--SLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKL 2100
V EQG +F+K V Y C C+ VL +P QT CG R+C SC+ LS SS C C+ ++ + + D R I AL+V C + C TL ++ H +NEC F + C C +K R L H + C+ R+ C C +P+I H C + CP+KC ++ + L H C + P C + GC + + H + + H + L + +E + LQ+++ + S++ L
Sbjct: 32 VPEQGGYKEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCT---ACQESII--KDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQ-----VPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSL 290
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q13114|TRAF3_HUMAN (TNF receptor-associated factor 3 OS=Homo sapiens OX=9606 GN=TRAF3 PE=1 SV=2) HSP 1 Score: 166.392 bits (420), Expect = 9.032e-42 Identity = 75/151 (49.67%), Postives = 103/151 (68.21%), Query Frame = 1
Query: 2197 DTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
+T NG IW I+++ K+EA G+ S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF IMRGEYD +L WPF+ KVTL ++DQ S + H ++F+PD F KPT + N+ASG P F+ + LEN YI ++ F+K+ V
Sbjct: 410 ETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 560 HSP 2 Score: 68.9366 bits (167), Expect = 2.021e-10 Identity = 72/269 (26.77%), Postives = 117/269 (43.49%), Query Frame = 1
Query: 1324 VTEQGF---QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSH-RNECLFVIVEC--DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEI--SLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKL 2100
V EQG +F+K V Y C C VL P QT CG R+C SC+ LS SS C C+ ++ + + D R I AL++ C ++ C L ++ H +N+C F + C C +K R L H + C+ R+ C C +P+I H C + CP+KC ++ + L H C + P C + GC + + H + + H + L + +E + LQ+++ + S++ L
Sbjct: 33 VPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCT---ACQESIV--KDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQ-----VPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSL 291
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P70191|TRAF5_MOUSE (TNF receptor-associated factor 5 OS=Mus musculus OX=10090 GN=Traf5 PE=1 SV=1) HSP 1 Score: 159.073 bits (401), Expect = 2.590e-39 Identity = 71/148 (47.97%), Postives = 97/148 (65.54%), Query Frame = 1
Query: 2212 NGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN----YIVNNGFFLKISV 2643
+G IW + ++ V K EA G S+ S PFYT GY+LC + Y NGDG GK THLS++F +MRGE+D +L WPFR +VTL +LDQ KKNH E+F+ D F +P + N+ASG P+F++ S LEN YI ++ FLK++V
Sbjct: 403 SGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAV 550 HSP 2 Score: 60.8474 bits (146), Expect = 7.658e-8 Identity = 70/299 (23.41%), Postives = 119/299 (39.80%), Query Frame = 1
Query: 1339 FQFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCI--VEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC-TTKDCEYITTLENINSHRNECLFVIVEC--DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLV-EHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITF---------DFDKVYSRH---LSQLQILSETKNQSV 2181
+QF++++ Y C C +VL +P QT CG R+C+ CI + L+ C D E + + + D R + L V C C L H C F V C + C + R + H C R+E C +C + L H + C Y CP +C + V EH +C CP+ GC +L +H L +H ++++ Y +E + +L ++ +++L F +++ R+ LS +Q L+ ++S
Sbjct: 33 YQFVEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQ------EVFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVKEHLSAYCRFREEKCLYCKRDIVVTNL-----QDHEENSCPAYPVSCPNRCVQTIPRARVNEHLTVCPEAEQDCPFKHYGCTVKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRISDLYQSLEQKESKIQQLAETVKKFEKELKQFTQMFGRNGTFLSNVQALTSHTDKSA 320
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: D5JG60 (TNF receptor-associated factor-2-like protein B OS=Dugesia japonica OX=6161 GN=TRAF-2B PE=2 SV=1) HSP 1 Score: 308.916 bits (790), Expect = 1.297e-89 Identity = 169/415 (40.72%), Postives = 242/415 (58.31%), Query Frame = 1
Query: 1375 CVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTL------DDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLE 2601
C+IC +L + +QT CGCRYC+ C+ E Y C + NI D A +R I L VKC CE+ L++I H + C+ + C C+++ T+ L H + +C R C CG L +H N+H LC K + CPYKC +E++L++HRK C KP C + E+GC+ + DL KH + H L+ + M++ + EL+ + E + LK +F K S L +++ L + + T + TV++NG +IW I+ FS LK EA+ G + SI SD FYT EFGYK+ MKIYP GDG+GK THLSVFFT+MRGE+D +L WPF+NKVTL+ILDQ +K N +S++F+PD++ C+ +PT D+N+ASGSPKFITFS L+
Sbjct: 30 CIICSQLLLEALQTDCGCRYCKECLKE------YQAKGKTKCLTDGCGDLGNIIPDNAVNREIGKLTVKCLFPGCEHSELLKDIGDHLDSCIHQTINCKSCNEELTKIELKEHTEKKCPMRLVSCTHCGEEMEYSNLTELHLNVHTEKLCAKLVGKCPYKCDNGKEVNLLDHRKSCSKKPVTCLFSEIGCNRVMTKEDLIKHNNEESLQHSRLLMKEIITMKNDISELKMKT-LEFNILK----IEFSKFQSEILDKIKSLEKIPRHTSPSTSSVRSSEEKTVYRNGVFIWKIERFSELKSEAERGNRISITSDYFYTKEFGYKMSMKIYPAGDGVGKGTHLSVFFTLMRGEFDDLLQWPFKNKVTLTILDQKNKTNDHSDTFKPDVRSTCYQQPTDDYNIASGSPKFITFSQLD 433
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1DBK6 (TRAF-4 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 281.952 bits (720), Expect = 5.153e-80 Identity = 157/427 (36.77%), Postives = 244/427 (57.14%), Query Frame = 1
Query: 1375 CVICKNVLTDPVQTSCGCRYCRSCIVEHL-SFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTL---DDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLENYIVNNGFFLKISV 2643
CV+C+++L D +QT CGCRYC+ CI +L + C + EDCR+ + T+ D A ++ I LKVKC + C + TL++I H + C + C C ++ H EC R+ +CQ+C + H RDLC KY ++CPY C + +++L+ HRK C +KP CP C L + +H+ + H ++ L +L+ Q + + LI + + + +L + + + S +L + T+F+NG Y+W IK FS L+E A G+ +I S+ FYT +FGYK+CMKIYP GDG+GK THLS+FF IM+G+YD IL WPF+NKV ++I D SK + S++F+PD K IC+ +P ++N+ASGSPKFI+FS L+N++ + +++I+V
Sbjct: 31 CVMCQDILLDAIQTDCGCRYCKECIDNYLENGEKECVAEYEDCRSVI----TSYIYDRATNKEISLLKVKCLYEGCVFEDTLKSIKGHLDFCEYRNEMCSLCGMEYIIKEESNHLANECLLREVLCQYCRTLLTFKEYNESHLCFESRDLCGKYEAICPYGCTGESKVNLLHHRKSCENKPLECPLHVFDCKQLIPKDQMTEHLNTSSYEHTLTIVTELR-------KLEKQNKHMEERMNILIEENQLLKATLEVMKLDLPKNSGSISRDTSLKRANKTIFRNGKYMWKIKSFSKLRENAMRGKNPTILSEAFYTSDFGYKMCMKIYPCGDGVGKGTHLSIFFVIMKGDYDDILPWPFKNKVIITIFDDFSKSTNLSDTFKPDPKSICYQRPEEEYNIASGSPKFISFSELKNFLKKDTLYIQINV 446
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: D5JG59 (TNF receptor-associated factor-2-like protein A OS=Dugesia japonica OX=6161 GN=TRAF-2A PE=2 SV=1) HSP 1 Score: 238.81 bits (608), Expect = 4.585e-66 Identity = 133/346 (38.44%), Postives = 203/346 (58.67%), Query Frame = 1
Query: 1633 HRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVD-LNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLD-----DTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN---YIVNNGFFLKISV 2643
H C + C++C KF H K +CE R C +CGI+ + L +IH N +LC KY+ +C C +++L +H KIC +K CP+ + C T + L KH++ NH S LI+++ +ES + +L+S+ H + K+L + SR L + + E K ++ ++ + +F+N ++IW +F V + +A++G + S+ SD FYT EFGYK+C+++YP GDG+GK THLSVFF IM+GE+D +L WPF+ KVTLSILDQ S +S++F+PD + C+ KPT + N+ASG PKFI S + N Y N+ FLKI+V
Sbjct: 4 HIESCDLREITCEKCGIKFGAKEKANHDKDKCEMRMVNCDYCGITMKSKDLNIIHLNPDRDELCSKYVGICSNNCNETRKVNLKDHLKICPNKKLECPFHQFDCKIDKMTKEKLMKHLDEEYFNHTSSLINKVKDLESKIIDLESELHNQILITKELFEMNKKSSESR-LKIEKTIEELKKKAPATSIQTIDNKNVIFRNASFIWKFTDFEVRRVDAESGGRVSVTSDAFYTSEFGYKMCLRVYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSILDQESGSKPHSDTFKPDARSACYQKPTDECNIASGFPKFILLSLIMNNSIYCKNDTIFLKIAV 348
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: L9J9C4 (TNF receptor-associated factor OS=Tupaia chinensis OX=246437 GN=TREES_T100001143 PE=3 SV=1) HSP 1 Score: 214.157 bits (544), Expect = 9.804e-56 Identity = 154/508 (30.31%), Postives = 242/508 (47.64%), Query Frame = 1
Query: 1273 FYPFQSLNSKLYNCHPEVTEQGF---QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSH-RNECLFVIVEC--DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEI--SLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCL------IDRLYLMESCLGELQS---------QAHRETDSLKKLI-----------------------TFDFDKVYSRHLSQLQILS-ETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
+P +S + ++ V EQG +F+K V Y C C+ VL +P QT CG R+C +C+ LS S C C+ +++ + D R I AL++ C ++ C TL ++ H +N+C F + C C ++ R L H + C+ R+ C C P+ L H C + CP+KC ++ + L H C + P C + GC + + H + + H + L +++ +++S +L+ Q E DS+K + T + SRH L + + ++ + +T NG IW I+++ K+EA G+ S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF IMRGEYD +L WPF+ KVTL ++DQ S + H ++F+PD F KPT + N+ASG P F+ + LEN YI ++ F+K+ V
Sbjct: 21 LHPDRSAGTAVF-----VPEQGGYREKFVKAVEDKYKCEKCRLVLCNPKQTECGHRFCETCMAALLSSSGPKCTA---CQESIVK--DKVFKDNCCKREILALQIYCRNESRGCAEQLTLGHLLVHLKNDCQFEELSCVRADCKERVLRKDLRDHVEKACKYREATCSHCKSQVPMVTL-----QKHEDTECPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 513
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: A0A2Y9JSN5 (TNF receptor-associated factor OS=Enhydra lutris kenyoni OX=391180 GN=LOC111148495 PE=3 SV=1) HSP 1 Score: 207.994 bits (528), Expect = 1.033e-53 Identity = 164/520 (31.54%), Postives = 254/520 (48.85%), Query Frame = 1
Query: 1243 IKPKKKINFYFYPFQSLNSKLYNCHPE---------VTEQGF---QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKD--CEYITTLENINSH-RNECLFVIVEC--DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCG----MKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERN---LINHFSCLID-RLYLMESCLGELQ--SQAHRETDSLKKLI-----------------------TFDFDKVYSRHLSQLQILS-ETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
++P KK++ + KL HP+ V EQG +F+K V Y C C+ VL +P QT CG R+C +C+ LS SS C C+ +++ + D R I AL++ C + C TL ++ H +N+C F + C C +K R L H + C+ R+ C C +PLI H C + CP+KC ++ E+SL+++ + +K + ++ C + ++ K M RN I H +ID + ++ E++ Q+ E DS+K + T + SRH L + + ++ + +T NG IW I+++ K+EA G+ S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF IMRGEYD +L WPF+ KVTL ++DQ S + H ++F+PD F KPT + N+ASG P F+ + LEN YI ++ F+K+ V
Sbjct: 1 MEPSKKLDPPGTLPPNPPLKL---HPDRGAASTSVFVPEQGGYKERFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCETCMAALLSSSSPKCTA---CQEGIIK--DKVFKDNCCKREILALQIYCRNEGEGCTEQLTLGHLLVHLKNDCQFEELSCIRADCKEKVLRRDLRDHVEKACKYREATCGHCKSQ-----VPLITLQKHEDTECPCVVVSCPHKCSVQTLLRSEVSLLQNESVEKNKSIQSLHNQI-CSF-EIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQSWEEADSVKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 505
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375]) HSP 1 Score: 179.489 bits (454), Expect = 5.357e-48 Identity = 137/469 (29.21%), Postives = 217/469 (46.27%), Query Frame = 1
Query: 1354 KVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINS-HRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKE--EISLVEHRKICFSKPFLCPYIEVGCD------------------YLFFTVDLNK-------------HMERNLINHFSCLIDRLYLMESCLGELQSQAHR-ETDSLKKLITFDFDKVYSRHLSQLQILS-ETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLE---NYIVNNGFFLKISV 2643
K+ + C IC+ +L P Q CG R+ + S++ D AA R ++AL+ C + C + T++ + H +C F+I+ C C + N L H + EC +R C++C F + N H ++C KY +C C K+ V+H K+C C + VGCD Y FTV L++ ++ + C+++R + E ++ HR + D ++ L + L L I+ E K + + D VF +W I +FS +++A AGR ++ S FYT ++GYK+C++IY NGDG G+ THLS+FF +MRG D +L WPF KVTL +LDQ + + H ++F+PDI F +P +D N+ASG P F S L+ +YI ++ F+K V
Sbjct: 27 KLEDKHLCNICQKILRRPFQAQCGHRFSPA--------SAF--------------------PDNAAKREVEALEAVCINEGCSWTGTIKEYEATHEGQCDFMIIPCPSCKELLRANELERHNERECPERTLNCKYCKEPFHFK------NIKAHDEICPKYPMIC-EGCAKKKIPREKYVDHIKLCTKFRTPCRFHVVGCDMSVSKPQWNLILTPRDLLYTSFTVPLSQTKVAELSRRCQELELKVGTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEILNNKVRQLERTVGLRDLSIVEMEGKMREMSAATYDGVF-----VWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQ-NNREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIV 454
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: ENSAMXT00000035169.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:3354744:3362219:1 gene:ENSAMXG00000029095.1 transcript:ENSAMXT00000035169.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 163.696 bits (413), Expect = 5.708e-46 Identity = 71/146 (48.63%), Postives = 100/146 (68.49%), Query Frame = 1
Query: 2212 NGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
NG IW I+++ K EA A + S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF +MRGEYD +L WPF+ KVTL ++DQ + H ++F+PD F +PT + N+ASG P F+ + LEN YI ++ F+K++V
Sbjct: 3 NGTLIWKIRDYKRRKAEAVASKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPARKHLGDAFKPDPNSSSFRRPTGEMNIASGCPLFVAQTVLENGTYIKDDTIFIKVTV 148
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252]) HSP 1 Score: 173.711 bits (439), Expect = 1.532e-45 Identity = 139/500 (27.80%), Postives = 238/500 (47.60%), Query Frame = 1
Query: 1360 PSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLS-----FSSYCCND--SEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECD-QCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISF-PLEILPLIHNNIHHRD----------LCVKYLSLCPYKCG----MKEEIS--------LVEH-RKICFSKPFLCPYIEVGCDYLFFTVDLN----------------------KHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLK-KLITFDFDKVYSRHLSQ--LQILSETKNQSVKCTLDDTVFK-----------NGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN----YIVNNGFFLKISV 2643
P + C C NVL + QT CG RYCR+C++ L + C D SE + +L ++ + +D A ++ I+ L+V C + C + +TL++ H+++C + ++ C+ C R L TH + C K CQ C + P E+ + + ++ +D CV C +K + E+S LVE R + S P P E Y + LN E + L RL +ME+ + L +RE + + ++ + D + +L Q +++E + + ++ L + + +G ++W I + S +EA G+K+S S FYT +G+K+CM++Y GDG+GK TH+S+FF IM+G+YDP+L WPF+ KVT ++DQ +++ H ++F+PD++ F +P ++ NVASG P F S L + Y+ ++ F+K V
Sbjct: 24 PVHFLCSSCNNVLNEAHQTQCGHRYCRACVMWLLRNNKDLICTKCKEDPGSESDSSMMLTLD-HFFSDNAINKEIQELRVHCVNQGCGWRSTLKDFEDHQSQCEYALIPCNIGCGLMVLRKTLATHLEKGCPNNKTTCQVCCSALTPAELQSVTYFSLFLKDSKQESPKRKETCVFSEIGCTFKGNPDKVREHEVSSTSAHLHLLVEVVRNVQMSVP---PPPERTVQYPALDLTLNGGELETDSGDTGANDKALSLHDDQAELEVGQQLHALQQRLQIMENIITAL----NREVEKTQLTVVVLERDNHNNMNLIQHLEAVVAEQQQRLIRKDLQISSLQQSISAQQDVSYDGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQ-NQREHVVDAFRPDLRSASFQRPVSEMNVASGCPLFFPLSKLRSPKHAYVKDDTLFIKCVV 514
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:103024022]) HSP 1 Score: 164.466 bits (415), Expect = 8.484e-43 Identity = 137/502 (27.29%), Postives = 221/502 (44.02%), Query Frame = 1
Query: 1339 FQFLKKVPSAYFCVICKNVLTDPVQTS-CGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSHRNECLFVIVEC-DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISF----------------------------------------PLEILP-------LIHNNIH-HRDLCVKYLSLCPYKCG---MKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQ----ISKKNHYSESFQPDIKLICFHKPTADFN------VASGSPKFITFSNL--ENYIVNNGFFLKISV 2643
++FL+K + C +C + +PVQ S CG R+C +C+ E LS + C + ++L I D + I AL ++C + + C + ++ + H + C F ++ C ++C+ K TR L H + +C KRK C+FCG F P P +++ I H+ C ++ CP +CG + E ++ C S LCP+ + GC + + + +H+E +H L +M S +G R+ + +L R + +L +V +G IW + ++S +EAK S PFYT +GYKL + + NG+G G+ +HLS++ ++ GEYD +L WPF KVT SILDQ +SK H +E+F PD F KP++ N + G PKFI+ + NYI +N FLK S+
Sbjct: 6 YKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPE-----DQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCAVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAFENHQGICPQESVYCENKCGARMMRRLLAQHTMAECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLATHVKESCGSALVLCPFKDAGCKHRCPKLAIGRHLEETTKSH-------LTMMCSLVG-------RQRQEIIEL---------RREMEEL-----------------SVSHDGVLIWKLNDYSRKLQEAKLHNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFAYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPSSSRNSLDESTLGFGYPKFISHDEIRKRNYIRDNAIFLKASI 462
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375]) HSP 1 Score: 145.206 bits (365), Expect = 1.363e-35 Identity = 66/147 (44.90%), Postives = 98/147 (66.67%), Query Frame = 1
Query: 2212 NGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLE---NYIVNNGFFLKISV 2643
+G ++W I +FS +++A AGR ++ S FYT ++GYK+C++IY NGDG G+ THLS+FF +MRG D +L WPF KVTL +LDQ + + H ++F+PDI F +P +D N+ASG P F S L+ +YI ++ F+K V
Sbjct: 422 DGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQ-NNREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIV 567 HSP 2 Score: 70.0922 bits (170), Expect = 9.751e-12 Identity = 66/248 (26.61%), Postives = 109/248 (43.95%), Query Frame = 1
Query: 1354 KVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIR------TDAAASRFIKALKVKCTTKDCEYITTLENINS-HRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKE--EISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQA 2070
K+ + C IC+ +L P Q CG R+C C + +S C S + ++ E T+I D AA R ++AL+ C + C + T++ + H +C F+I+ C C + N L H + EC +R C++C F + N H ++C KY +C C K+ V+H K+C C + VGCD ++ H H + L+ + ++ L LQ Q+
Sbjct: 27 KLEDKHLCNICQKILRRPFQAQCGHRFCSYCFNKTVSSGPQKC--SACIKEDIFEEPTSILKQGCAFPDNAAKREVEALEAVCINEGCSWTGTIKEYEATHEGQCDFMIIPCPSCKELLRANELERHNERECPERTLNCKYCKEPFHFK------NIKAHDEICPKYPMIC-EGCAKKKIPREKYVDHIKLCTKFRTPCRFHVVGCDMSVEKEKIHDHERACSYEHLNLLLHFIMGIKVNLESLQPQS 265
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 166.777 bits (421), Expect = 1.035e-44 Identity = 71/151 (47.02%), Postives = 104/151 (68.87%), Query Frame = 1
Query: 2197 DTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLE--NYIVNNGFFLKISV 2643
+T +G +W I++++ K+EA +GR S+ S PFYT FGYK+C + Y NGDG+G+ THLS+FF +MRGEYD +L WPFR +VTLS+LDQ + + H S++F PD F +P D NVASG P F++ LE +Y+V++ F+++ V
Sbjct: 262 ETAGYSGKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTFTPDPASGSFRRPDGDMNVASGCPLFVSHVALEGSSYLVDDTVFVRVVV 412
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 166.777 bits (421), Expect = 3.613e-44 Identity = 75/181 (41.44%), Postives = 118/181 (65.19%), Query Frame = 1
Query: 2113 FDKVYSRHLSQLQILSETK--NQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLE--NYIVNNGFFLKISV 2643
D SRH +QL +T+ ++ + +T NG +W I++++ K++A +GR S+ S PFYT FGY++C + Y NGDG+G+ THLS+FF +MRGEYD +L WPFR +VTL++LDQ + + S++F+PD F +PT+D N+ASG P F++ LE +Y+ ++ F+K+ V
Sbjct: 290 LDSALSRHDTQL-FAHDTRLAEMDLRFQVLETASYNGKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSDTFKPDPASSSFRRPTSDMNIASGCPLFVSHVALESASYLQDDTIFIKVVV 469 HSP 2 Score: 58.9214 bits (141), Expect = 5.620e-9 Identity = 65/237 (27.43%), Postives = 98/237 (41.35%), Query Frame = 1
Query: 1555 RFIKALKVKCT--TKDCEYITTLENINSHRNECLFVIVECDQ--CSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCG----MKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKE 2241
R I AL+V C T C+ I L + H C+ V C C+++ R L+ H + C R E C++C + +PL H+ C +Y CP KC +EE LV H IC K C + + GC Y L +H H S + R +E + LQSQ +S L+ ++ +S Q S KN+SV C + + + ++E
Sbjct: 10 REILALRVHCRNDTAGCKQIVELGKLQEHMAVCVHEAVNCPHAGCTERLLRGELVNHVALGCHFRTESCRYCN-----QQVPLAEKRKHYETRCPRYPIPCPNKCEEQSIAREE--LVSHLGICPYKQAECFFSQFGCKYKGTLQGLKEHESGATQQHLSLVTARSANLELKVSMLQSQLAERANS-ADLLGTRVRELEKELISVGQTAS--KNESVLCVVQRMLAVQTERLLRLQE 236
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 112.079 bits (279), Expect = 1.417e-25 Identity = 125/508 (24.61%), Postives = 203/508 (39.96%), Query Frame = 1
Query: 1333 QGFQ--FLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEI---SLVEHRKI-CFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRL---------------------------YLMESCLGELQ------SQAHR---------ETDSLKKLITFDFDKVYSRHLSQLQILS-ETKNQS--------------VKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDP----------FYTGEFGYKLCMKI-------YPNGDG------LGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKN-HYSESFQPDIKLICFHKPTADFNVASGSPKFITFSN 2595
QG++ F + S Y C IC L +PVQT CG R+CR+CI+ + D N +L E + D A R I +L V+C K C + L + H+ C + V C +C R L H++ EC +R C C + ++ +H +C + C + ++E+ L H ++ C C + +GC+ L HM + H L + L +L + G++Q SQ R E D L++ IT ++ L Q++ LS +T NQ + ++ G + W ++ FS L A AS P FYTG GY+LC+++ P G G+Q HL++F +++G+YD L WPF+ ++ +S++DQ + + H +E D +L F +P+ N PK + N
Sbjct: 49 QGYEADFEPPLESKYECPICLMALREPVQTPCGHRFCRACILHSMRLRDAGPKCPVD--NAVLH-EGQLFPDNFAKREILSLTVRCPNKPCGHRGELRALQEHQLRCEYAQVPCVRCEMPVCRRDLAKHEEQECMRRIVTCLHCCEKMAYK------DSKNHEQMCPLVVVNCKH---CQQELIREQLGPHLEVDCQQAQVPCTFSPLGCEAQMVRSLLAAHMHEHTQVHMRLLANGLKILRIQVGQGAQPSSAAGSSAPPNSLSWLSSTSGGDVQTAGASRSQGSRDRAACDCAQELDRLRE-ITRTLEERVVLQLHQIRELSAKTDNQQGLLAEATRLVRSLEARVAESESRLCAGIFTWRVERFSRLLPGGLASGFASDGMHPDAPAVMHSSGFYTGVPGYRLCLRLQVLSGREVPAGAASPSVLLAGRQPHLALFVHLLQGDYDHRLPWPFKGRIRISVVDQCERDSVHVTEMMDADPQLSAFQRPSVHRN-----PKGFGYMN 538
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008091.1 (pep scaffold:Pmarinus_7.0:GL477915:34322:50582:-1 gene:ENSPMAG00000007312.1 transcript:ENSPMAT00000008091.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 93.2041 bits (230), Expect = 4.042e-20 Identity = 102/411 (24.82%), Postives = 165/411 (40.15%), Query Frame = 1
Query: 1363 SAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKDCEYITT-LENINSHRNECLFVIVECDQCSKKFT--RNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLID-----------------------RLYLMESCLGELQSQAH----------RETDSLKKLITFDFDKV-----------YSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAG--RKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNK 2448
+ + C C+ +L D VQT CG R+C+ CI ++ CND+ N L+ T DAA R + L V+C ++ CE+ LE +H C +V+V C R L H EC R C C P L + +H R + LC K +++ E R+ C CPY +GC Y L+ H + ++ H + + D RL E+ L + + R +++ + D D+ +S ++ IL T+ + L++T + NG ++W IK EA G R I S F+T +GY+L +++ +G+ H+S + + G YD L WP++ K
Sbjct: 1 ARFACGSCQGLLRDAVQTHCGHRFCKPCIARLITSVHRSCNDTLMNSNFLVYSPTQFFPDAALRREMGVLPVRCVSEGCEWRGRLLEYDVAHVERCDWVLVPCLLAGCALLLPRAELHRHVAQECSVRPVPCAACAQLLPYR--QLQKHQLHCRSRRTRECKLCGQKSIPEDKWQHHEERR-CMKNRDTCPYSPLGCLYRGHGESLHNHDKNSVEVHLAIVYDAFKKTFEQLIKGHADNIKHPPSARLVAAEAQLATMDRRVEEVAKRVERDVRVSEASTRQGNIDRDETARLQNKMARVEHSDQETERSILGLTRRLA---ELENTAY-NGMFLWKIKHVINRLREAGNGAERPPQIDSPAFFTTRYGYRLRLRLCRSGE------HVSAYAMLGPGPYDATLAWPYQLK 398
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007705.1 (pep scaffold:Pmarinus_7.0:GL484572:34:4229:-1 gene:ENSPMAG00000006959.1 transcript:ENSPMAT00000007705.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 54.6842 bits (130), Expect = 7.698e-8 Identity = 28/105 (26.67%), Postives = 52/105 (49.52%), Query Frame = -2
Query: 3712 K*LFRLIMWMGIVKLPEAHLYWSKDAAYPQSFHSSVLSRNRFELLLRMLHF-----CDIENENLNDSLHKIRVIIDMINENF*KYYDPGEIVCVDKSLISFQGRI 4011
K F + + MGI LP YWS + A + S ++ R+ + + LH + D ++K+R +++ + NF ++Y P + VD+ +I F+GR+
Sbjct: 10 KAFFAVAIMMGIKDLPRVWCYWSGNPALRCEWVSGTMTHTRYSKVSQYLHARNNVGTPARGQRGYDPIYKVRNVVEEVRANFSRHYSPRRELSVDEGMIPFKGRL 114
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO38873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBN4]) HSP 1 Score: 163.696 bits (413), Expect = 7.358e-43 Identity = 145/478 (30.33%), Postives = 220/478 (46.03%), Query Frame = 1
Query: 1357 VPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTK--DCEYITTLENINSHRNECLFVIVEC--DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLC-PYIE--VGCDYLFFTVDLNKHMERNL--------INHFSCLIDRLYLMESCLGE-----------------LQSQAHRETDSLKKLITF------DFDKVYSRHLSQLQILSET---KNQSVK------CTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
+ + + C C+ ++ D VQT+CG RYC CI LS C+ C + + + ET D A R I L V C + C + L + +H +C F + C +C KK + L H + EC+ R+E C +C P+ + + HH C Y CP KC KE I + H S PF P +E GC+ ++ ++ + L +N + + +G+ L +AH D L++ + + D + R QL++ + +N ++ TL T F + +W I + + EA +GR S S F+TG GYK+C +IY NGDG+G+ H+S+FF IMRGE+D +L WPFR KVTL +LDQ H ++F+PD F +P A+ N+ASG P F + L YI ++ FLKI V
Sbjct: 18 IAAKHLCAKCRLIVKDAVQTACGHRYCSPCISPLLSRGPIQCDV---CGSTITKPETF--RDKFADREILELHVHCVNQPHGCPWEGELRHRQNHHTKCEFNPISCVHPECGKKLSVAKLPEHLQNECQYREETCSYC--EQPVVVARMKE---HHEKTCPSYPVNCP-KCS-KELIRVEVH-----STPFTREPRLEKGRGCENTLEVLEDHESRIKKLEQRGGGIGVNGLQSMRISENIDNEAIGDVLRRVANVEAKGADHEVLVVEAHSAVDELRREVGRLNVKLQESDDIIRRLERQLELHDQGTGLRNLAIADLEERLNTLQGTTF-DSVLLWKITNVANKRSEATSGRVTSFYSPCFFTGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQ-DNVEHVIDAFRPDPSSSSFQRPRAEMNIASGCPLFCSHEQLTQHAYIRDDTMFLKIIV 476
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO41243 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z7]) HSP 1 Score: 157.532 bits (397), Expect = 6.375e-41 Identity = 133/509 (26.13%), Postives = 214/509 (42.04%), Query Frame = 1
Query: 1318 PEVTEQGF--QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSY--CCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQ--CSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEI-----------------------LPLIHNNIH--------------------------HRDLCVKYLSLCPYKCGMK-EEISLVEHR-KICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLG---ELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQ---ISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNL--ENYIVNNGFFLKISVGN 2649
P G+ +F+ V Y C IC L PVQT CG R+C+ C+ E S C D E L+++ ++ D AA R I + VKC K C++ L ++ +H C + +V C CS + R + H +EC+ R +C++CG P + LP + + H H + C K+ LCP CG + L +H+ + C C + + GC+ +++H++ N+ +H + ++L L ELQ R + LK ++W I +F+ +AK G K + S+PF+T + GYKL +YPNG GK TH+S F +I RGEYD IL WPF + +++LDQ + ++ + ++ P+ L FH+P N GS F++ L ENY+V+ F+++ V +
Sbjct: 4 PSPVPSGYDSEFVIAVAEEYTCRICHLPLRVPVQTKCGHRFCKECLDEASRRKSRAECPMDREP-----LDLKKDVFLDKAAERTILSFLVKCPCKGCKWEAELRDLEAHARNCDYELVTCSNPMCSAQLPRMDVDEHLLVECDWRLIVCEYCGDESPYCLQKAHARNCDYKLVTCSNPMCSAQLPRMDVDEHLLVECDWRLIVCEYCGDESPYCLQKDHSNQCDKFPVLCPNDCGTQITREKLRDHQSEECQFAVVPCAFRDFGCEVEIQNRLMDQHLDTNIQSHLNMTCNQLLLSRDSGAQFHELQQGLGRVNELLKM----------------------------------------RFVWRIPDFADSLRQAKLGLKVRLDSEPFFTEKNGYKLRATLYPNGTMSGKNTHISAFVSINRGEYDGILAWPFTRVIKITLLDQKENVLQRRNVEKTIIPNPSLENFHRPKTVSNNGRGSATFVSHEKLWTENYVVDGTLFMQVEVSS 467
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO49464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG36]) HSP 1 Score: 157.918 bits (398), Expect = 1.407e-40 Identity = 73/183 (39.89%), Postives = 114/183 (62.30%), Query Frame = 1
Query: 2104 TFDFDKVYSRHLSQLQILS-ETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
T ++ R+ QL + + +K + + +G YIW I E++ +E +G+ SI S PFY G +GYK C ++YPNGDG+GK +HLS+FF +MRGE+D +L WPFR KVT +LDQ + + ++F+PD F +PT++ N+ASG P FI+ +NL+ Y+ ++ F+KI+V
Sbjct: 340 TMALERRQDRNEHQLALHDIQLAEHDLKLQMLEATSYDGTYIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLDQ-DRVHDIGDTFRPDPTSSSFKRPTSNMNIASGCPLFISHTNLQTRAYVRDDTMFIKIAV 521 HSP 2 Score: 67.781 bits (164), Expect = 2.095e-11 Identity = 66/258 (25.58%), Postives = 105/258 (40.70%), Query Frame = 1
Query: 1324 VTEQGFQ---FLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKD--CEYITTLENINSHRNECLFVIVECDQ--CSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKE--EISLVEHR-KICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQ 2067
+ ++GFQ F++ + Y C +C N L PVQT CG R+C C+ L S C D E+ + + + D R I L C + CE++ L+ + HR C + V+C C +K + L H CE + CQ+C P + H C K+ +CP+ CG + L+ H+ IC C + + GC + L H H + L+ E E+ ++
Sbjct: 1 MQDEGFQTELFVEPLDPKYRCPVCGNALKHPVQTPCGHRFCEGCLEPILRGPSKCPVDGEELKID------GVFKDVCCRREILCLACYCPNRQLGCEWMKDLQYLEEHRANCEYKGVQCHNPGCQEKVAKRDLEAH-LERCEFKPSDCQYCLQRIPAASME------DHLQTCEKHPVVCPH-CGAEGICRDELLHHQTNICEQAELPCSFAKHGCHFKGTREALETHFRDQASVHVNLLLTATQNEEKARSEMAAK 244
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO49545 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGK7]) HSP 1 Score: 147.902 bits (372), Expect = 3.989e-38 Identity = 130/452 (28.76%), Postives = 195/452 (43.14%), Query Frame = 1
Query: 1342 QFLKKVPSAYFCVICKNVLTDPVQ-TSCGCRYCRSCIVE--HLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTT--KDCEYITTLENINSHRNECLFVIVEC--DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMK----EEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAG-RKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKL----ICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
+F++ +P Y C IC+ DP+Q CG R+C+SC+ E L S C + T + D AA R I L VKC + CE+ L NI H C V C +C++ R L H +C+ R C FC + + + H C + C KCG K EE+ H C C Y ++GC + L +H + + H + + Q RE +S R L CT NG ++W I + ++A A + +I S PFYT ++GYKL +K Y NG GK THLS++ IM+G+YD +L WPF+ K+T ++DQ K+NH + P+ L + F++PT N+ G+P F+ LE+ Y+ ++ F+K V
Sbjct: 15 EFVEPLPEEYECPICQLAFRDPIQIEECGHRFCQSCLQELRRLQGSPVLCP-----MDRRPISSTKVFVDKAARRAILGLGVKCWNWKRKCEWTGELSNIEEHAKNCAHEDVHCTNPECNEVMPRRSLQYHLVSKCKWRIVSCHFCTEMYTYK------DGKTHMKSCKRLPIECVNKCGAKDIPREEMPF--HMSECPLAVHPCMYRDIGCPFKGRRDALEEHCKNAVHTHLN---------------IACQKIRENES--------------RSL---------------CT-------NGIFLWKISNYKHQYDQAVASPEELAIFSPPFYTSQYGYKLRLKAYLNGRDRGKGTHLSLYIIIMKGDYDALLEWPFKQKITFYLIDQSEKQNHRTHLLSPNRSLPNIKVVFNRPTVKENLGIGNPCFVPNEVLESGEYVKDDVMFIKAVV 402
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO35237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM27]) HSP 1 Score: 144.821 bits (364), Expect = 3.412e-36 Identity = 73/179 (40.78%), Postives = 111/179 (62.01%), Query Frame = 1
Query: 2128 SRHLSQLQ---ILSETK--NQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNL--ENYIVNNGFFLKISV 2643
+R LSQL+ + +TK + ++ + + +G ++W I +F+ EAK+G SI S PFYT FGYKLC +++PNGDG + +LS+F +MRGEYD IL WPF+ +T++++DQ + N SE+F PD I F +PT + NVASG P+F + + L Y+ N F+K+ V
Sbjct: 346 NRRLSQLESSITIHKTKLFQEDLRIQIQQAISYDGTFLWKIDKFTERYAEAKSGNATSIYSSPFYTHRFGYKLCARLFPNGDGSARDNYLSIFIALMRGEYDSILPWPFQETITITLIDQDNGMN-ISETFDPDPCSISFQRPTRNINVASGCPRFCSQTVLRTRGYMNENCVFVKVVV 523 HSP 2 Score: 65.4698 bits (158), Expect = 1.120e-10 Identity = 66/254 (25.98%), Postives = 104/254 (40.94%), Query Frame = 1
Query: 1342 QFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCI-VEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTK--DCEYITTLENINSHRNECLFVIVEC----DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMK--EEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHR 2076
+++ + Y C C+ L P+Q CG R+C+ CI V +S C D + + ++ D A ++AL C + C++ + I H C F+ V C D C + R L H + EC R C +C P L I H C + CP +CG+K E L H + C + C + +GC Y + L +H +++I H L + L EL++Q R
Sbjct: 1 EYIDVLEDRYICNACRMPLNHPMQAQCGHRFCKHCIDVILISPFPACPRDGQTIQ------ALSVFHDRCALVEMQALPCYCHGRCDGCQWTGPVAMITVHEEVCAFIKVSCIHASDGCGEIMLRFQLAKHVEKECPFRLITCVYCQNDVPERTL------IEHLKKCPAFPIECPNECGVKRIERKKLSAHTRECPNALTDCRFSPLGCTYKVKKIALREHQNKHVIKHMILLGRTTGEPQPNLLELENQLER 242
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf3 (TNF receptor associated factor 3 [Source:NCBI gene;Acc:101161601]) HSP 1 Score: 202.601 bits (514), Expect = 6.148e-56 Identity = 146/448 (32.59%), Postives = 218/448 (48.66%), Query Frame = 1
Query: 1336 GFQ--FLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLS-FSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTK--DCEYITTLENINSHRNECLFVIVEC--DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYL--MESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILS-ETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN--YIVNNGFFLKISV 2643
GF+ F++ + Y C C+ VL P QT CG R+C SCI + LS + C D E + I D R I ALKV C ++ C+ +L+ I H N C F V C +C ++ R + H +C+ R+ C+FC PL L H +C + CP C SL K+ ++ H E+ L R MES G L + R +L++ + +RH L + + ++ + +T NG IW I+++ K++A AG+ S+ S PFYTG FGYK+C ++Y NGDG+GK THLS+FF +MRGEYD +L WPF+ KVTL ++DQ + H ++F+PD F +P A+ N+ASG P F++ S LE+ YI ++ F+K++V
Sbjct: 33 GFRDHFVEAPEAKYCCEACRLVLCQPRQTECGHRFCYSCINDILSCPNPVCPADMEPL------FKDKIFRDVCCHREIMALKVYCRSEANGCQEQMSLQQIPDHVNVCPFFEVPCPLGKCKERMMRKEIPEHLAWKCKYRESTCEFCKNKMPLTEL-----QKHKETVCPAFPVSCPNHCTSS---SLPRSEKL-----------------------MSSHTEKLLELELELRSLRQLRDEMESLRGTLDTVRTR-LSALEQGGRASLETQLNRHDDMLSVHEIRLADMDLRFQVLETASYNGTLIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPSRKHLGDAFKPDPSSSSFRRPVAEMNIASGCPLFVSQSVLESGTYIKDDTIFIKVTV 442
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 182.956 bits (463), Expect = 1.292e-48 Identity = 140/495 (28.28%), Postives = 224/495 (45.25%), Query Frame = 1
Query: 1369 YFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEME-------TNIRTDAAASRFIKALKVKCTTKDCEYITTLENINS-HRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKE--EISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLID------RLYLMESCLGELQSQA----HRETD----SLKKLITFDFDK----------VYSRHLSQLQILSET------------KNQSVKC-------TLDDTVFK--------------NGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN---YIVNNGFFLKISV 2643
Y C C VL PVQ CG R+C C + S C + CR E + E + D AA R I +L +C + C++ +++ + H C F ++C+ C R H ECE+R C++C ++F + + H ++C K+ C CG K+ +H K C CP+ EVGC + +++H + + H L+ R L S GE Q + +R D + + + D DK V +R + + + E +N S K T+ D +G ++W I +FS ++EA +GR ++ S FY+ ++GYK+C+++Y NGDG G+ THLS+FF +MR +YD +L WPF KVTL +LDQ + + H ++F+PDI F +P ++ N+ASG P F + L Y+ ++ F+K V
Sbjct: 28 YKCQQCLQVLRKPVQAQCGHRFCVHCFRQLTSSGPKPC---QACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARCLNQGCDWTGSIKEYEAKHEGRCEFEQIQCEACQALVLRKDKDRHNDRECEERTLNCKYCKVTFNFKDIKA------HDEICQKFPLQC-KDCGKKKIPREKFNDHAKSCAKSKSACPFSEVGCKSVVENGKISEHEHSSTMEHLRLLLPMVLSMTRTRLDTSPSGEWQEDSGLGLYRAPDDGCGAAASVPSVDLDKKVSALENIVCVLNREVERSSLTLEAFSHQHRLDQEKIENLSNKIRQLERSLTVKDLQLSEAEQMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQ-NNREHIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIV 511
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 182.57 bits (462), Expect = 1.852e-48 Identity = 140/495 (28.28%), Postives = 224/495 (45.25%), Query Frame = 1
Query: 1369 YFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEME-------TNIRTDAAASRFIKALKVKCTTKDCEYITTLENINS-HRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKE--EISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLID------RLYLMESCLGELQSQA----HRETD----SLKKLITFDFDK----------VYSRHLSQLQILSET------------KNQSVKC-------TLDDTVFK--------------NGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN---YIVNNGFFLKISV 2643
Y C C VL PVQ CG R+C C + S C + CR E + E + D AA R I +L +C + C++ +++ + H C F ++C+ C R H ECE+R C++C ++F + + H ++C K+ C CG K+ +H K C CP+ EVGC + +++H + + H L+ R L S GE Q + +R D + + + D DK V +R + + + E +N S K T+ D +G ++W I +FS ++EA +GR ++ S FY+ ++GYK+C+++Y NGDG G+ THLS+FF +MR +YD +L WPF KVTL +LDQ + + H ++F+PDI F +P ++ N+ASG P F + L Y+ ++ F+K V
Sbjct: 35 YKCQQCLQVLRKPVQAQCGHRFCVHCFRQLTSSGPKPC---QACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARCLNQGCDWTGSIKEYEAKHEGRCEFEQIQCEACQALVLRKDKDRHNDRECEERTLNCKYCKVTFNFKDIKA------HDEICQKFPLQC-KDCGKKKIPREKFNDHAKSCAKSKSACPFSEVGCKSVVENGKISEHEHSSTMEHLRLLLPMVLSMTRTRLDTSPSGEWQEDSGLGLYRAPDDGCGAAASVPSVDLDKKVSALENIVCVLNREVERSSLTLEAFSHQHRLDQEKIENLSNKIRQLERSLTVKDLQLSEAEQMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQ-NNREHIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIV 518
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 161.77 bits (408), Expect = 7.913e-42 Identity = 140/480 (29.17%), Postives = 221/480 (46.04%), Query Frame = 1
Query: 1339 FQFLKKVPSAYFCVICKNVLTDPVQTS-CGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSHRNECLFVIVEC-DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKIC----FSKP-----------------FLCPYIEVGCDYLFFTVDLNKHMERNLINHF-----SCLIDRLYLMESC---LGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQ----ISKKNHYSESFQPDIKLICFHKPTADFN------VASGSPKFITFSNLE--NYIVNNGFFLKISV 2643
++FL+K + C +C + +PVQ S CG R+C +C+ E LS + C + ++L I D + I +L ++C + + C + ++ + H + C F ++ C ++CS K TR L H + +C KRK C+FCG F E +H+ +C + C KCG + L+ + ++P F CP V C T ++ + +L NH S L+ + C +L H E D+ K +T + V + L++ E + SV +G IW + ++S +EAK S PFYT +GYKL + + NG+G G+ +HLSV+ ++ GEYD +L WPF KVT SILDQ +SK H +E+F PD F KP + N + G PKFI+ ++ NYI +N F+K S+
Sbjct: 6 YKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPE-----DQLPLDYAKIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEFTGEAFE------NHQGVCPQESVYCENKCGARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPRFPVQCPNQCGTPNIARE---DLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRHLE-DTTKSHLTMMCNLVSRQRQEILELRREMEELSVS--------HDGVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEIKKRNYIRDNCIFIKASI 462
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 161.77 bits (408), Expect = 1.170e-41 Identity = 140/480 (29.17%), Postives = 221/480 (46.04%), Query Frame = 1
Query: 1339 FQFLKKVPSAYFCVICKNVLTDPVQTS-CGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKC--TTKDCEYITTLENINSHRNECLFVIVEC-DQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKIC----FSKP-----------------FLCPYIEVGCDYLFFTVDLNKHMERNLINHF-----SCLIDRLYLMESC---LGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQ----ISKKNHYSESFQPDIKLICFHKPTADFN------VASGSPKFITFSNLE--NYIVNNGFFLKISV 2643
++FL+K + C +C + +PVQ S CG R+C +C+ E LS + C + ++L I D + I +L ++C + + C + ++ + H + C F ++ C ++CS K TR L H + +C KRK C+FCG F E +H+ +C + C KCG + L+ + ++P F CP V C T ++ + +L NH S L+ + C +L H E D+ K +T + V + L++ E + SV +G IW + ++S +EAK S PFYT +GYKL + + NG+G G+ +HLSV+ ++ GEYD +L WPF KVT SILDQ +SK H +E+F PD F KP + N + G PKFI+ ++ NYI +N F+K S+
Sbjct: 6 YKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPE-----DQLPLDYAKIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEFTGEAFE------NHQGVCPQESVYCENKCGARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPRFPVQCPNQCGTPNIARE---DLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRHLE-DTTKSHLTMMCNLVSRQRQEILELRREMEELSVS--------HDGVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEIKKRNYIRDNCIFIKASI 462
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000039087.1 (SMESG000039087.1) HSP 1 Score: 926.776 bits (2394), Expect = 0.000e+0 Identity = 466/478 (97.49%), Postives = 470/478 (98.33%), Query Frame = 1
Query: 1216 MPLKFIYEYIKPKKKINFYFYPFQSLNSKLYNCHPEVTEQGFQFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLENYIVNNGFFLKISVGN 2649
MPLKFIYEYI+PK K NFYFYPFQSLNSKLYNCHPEVTEQGFQFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIV+HLSFSSYCCNDSEDCRNELLE+ETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQCSKKFTRNYLLTHKKIECEKRKEICQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHME N INHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDK YSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKA R ASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSE+F PDIKLICFHKPTADFNVASGSPKFITFSNLENYIVNNGFFLKISVGN
Sbjct: 1 MPLKFIYEYIQPKNKNNFYFYPFQSLNSKLYNCHPEVTEQGFQFLKKVPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVKHLSFSSYCCNDSEDCRNELLELETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQCSKKFTRNYLLTHKKIECEKRKEICQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMELNSINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKDYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKADRIASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSETFLPDIKLICFHKPTADFNVASGSPKFITFSNLENYIVNNGFFLKISVGN 478
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000027153.1 (SMESG000027153.1) HSP 1 Score: 298.901 bits (764), Expect = 3.005e-89 Identity = 167/434 (38.48%), Postives = 249/434 (57.37%), Query Frame = 1
Query: 1375 CVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSE-DCRNELLEMETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVD-LNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQ-ILSETKNQSVKCTLD-----DTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNLEN---YIVNNGFFLKISV 2643
CV+C+ +L + QTSCGC+ C +CI +L+ C + DC N +L M+ +I D A ++ I +LKVKC K C L N+ H N C F + C++C K +H K +CE RK C++C L IH N D CVKY ++CP C + ++ L EH K+C K CP+ + C+ T + L KH+ ++H S LI ++ ME+ + L + + K+L+ D +K S + + Q + + K +S + +F+N +IW +F + +A++GRK S+ SDPFYT EFGYK+C++IYP GDG+GK THLSVFF IM+GE+D +L WPF+ KVTLSI+DQ + H+S++F+PD + C+ KP + N+ASGSPKFI S + N Y N+ +LKI+V
Sbjct: 28 CVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELL--DMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAV 459
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000039089.1 (SMESG000039089.1) HSP 1 Score: 293.893 bits (751), Expect = 1.305e-87 Identity = 164/444 (36.94%), Postives = 249/444 (56.08%), Query Frame = 1
Query: 1375 CVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQS------------------VKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNL-ENYIVNNGFFLKISVGN 2649
CVIC +L + +QT CGCRYC+ CI +HL S C ++ C + M D A ++ I L VKC C + L++I H N C ++ V C++C + L H +C KR C C EIL H +++ ++C K + CPY C + ++L+ HRK C KP CP++E+GC + L+ HM+ H L++ M+ + L+++ + ++K L +F S +S + +S + +K + ++NG +IW ++ F LK A+ G + S+ S+PFYT EFGYK+ MKIYP GDG+GK THLSVFFT+M+G++D +LVWPF+NKVTL+ILDQ +K + YS++F+PD + C+ +PT ++N+ASGSPKFI+F+ L E Y+ N+ FLKI V N
Sbjct: 30 CVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQC--STKGCSTIISTM-----PDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRVVKCLNCESRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFPAHIRTLVEEFIKMKKEITSLETKLIESSKTIK-LELSNFQNEISTKISNIDQMSNSSLSLQSSSSLTLQSSASSMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQEYYMKNDTIFLKIVVLN 465
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000027123.1 (SMESG000027123.1) HSP 1 Score: 267.314 bits (682), Expect = 1.894e-78 Identity = 159/436 (36.47%), Postives = 239/436 (54.82%), Query Frame = 1
Query: 1357 VPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLM----ESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNL---ENYIVNNGFFLKISV 2643
+ S+ C+IC ++L + QT CGC+ C +CI E+LS C + E C NELL ++ +I D A ++ I LK+ C K C + T+ I+ H C + V CD C K+ H ECE R C+FC + ++ L +H N +LC +Y+ CP CG +E++L H + C ++ D N H++ S L+ ++ L+ + L +L++Q + K I D + + ++ L ++ VK F+NG++IW IK+ + A+ + SI SDPFYT EFGYKLC+++YP+GDGLGK THLSVFF +M+GEYD +L WPFR K+TLS+LDQ + HYS++F+PD K CF +P D N+ASGSPKF + S+L Y N+ ++KI+V
Sbjct: 21 LSSSLKCIICSSLLKNAKQTKCGCKVCENCINEYLSKGPKDCPNKE-CLNELLSIDKDIYNDNATNKEILNLKIACPFKGCAQLETVFKISQHVKSCEYRDVTCDPCQKRILAKEKQKHIDGECEMRITKCEFCHKTMTIKYLNEMHLNTTKNELCSEYVGHCPNNCGETKELNLKLHLETCLNRKS------------DDQNDTNYHIQEFSNTQLSNLLKQIALLNQTSKDLLTKLENQDVIIREMSTKYIALTEDNI--KLTKKINALEAERSNPVKIIAKTNDFRNGSFIWKIKDLKSQIQNAERSERLSITSDPFYTSEFGYKLCLRVYPSGDGLGKGTHLSVFFALMKGEYDDLLPWPFRQKLTLSLLDQENFTKHYSDTFKPDPKSPCFQRPILDSNIASGSPKFYSISHLSFNSIYYKNDTIYIKITV 441
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000027123.1 (SMESG000027123.1) HSP 1 Score: 230.72 bits (587), Expect = 7.805e-66 Identity = 149/436 (34.17%), Postives = 225/436 (51.61%), Query Frame = 1
Query: 1357 VPSAYFCVICKNVLTDPVQTSCGCRYCRSCIVEHLSFSSYCCNDSEDCRNELLEMETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQCSKKFTRNYLLTHXXXXXXXXXXXXQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMERNLINHFSCLIDRLYLM----ESCLGELQSQAHRETDSLKKLITFDFDKVYSRHLSQLQILSETKNQSVKCTLDDTVFKNGNYIWHIKEFSVLKEEAKAGRKASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSESFQPDIKLICFHKPTADFNVASGSPKFITFSNL---ENYIVNNGFFLKISV 2643
+ S+ C+IC ++L + QT CGC+ C +CI E+LS C + E C NELL ++ +I D A ++ I LK+ C K C + T+ I+ H C + V CD C K+ H ECE R C+FC + ++ L +H N +LC +Y+ CP CG +E++L H + C ++ D N H++ S L+ ++ L+ + L +L++Q + K I D + + ++ L ++ VK F+NG++IW IK+ + A+ + SI SDPFYT DGLGK THLSVFF +M+GEYD +L WPFR K+TLS+LDQ + HYS++F+PD K CF +P D N+ASGSPKF + S+L Y N+ ++KI+V
Sbjct: 21 LSSSLKCIICSSLLKNAKQTKCGCKVCENCINEYLSKGPKDCPNKE-CLNELLSIDKDIYNDNATNKEILNLKIACPFKGCAQLETVFKISQHVKSCEYRDVTCDPCQKRILAKEKQKHIDGECEMRITKCEFCHKTMTIKYLNEMHLNTTKNELCSEYVGHCPNNCGETKELNLKLHLETCLNRKS------------DDQNDTNYHIQEFSNTQLSNLLKQIALLNQTSKDLLTKLENQDVIIREMSTKYIALTEDNI--KLTKKINALEAERSNPVKIIAKTNDFRNGSFIWKIKDLKSQIQNAERSERLSITSDPFYTS--------------DGLGKGTHLSVFFALMKGEYDDLLPWPFRQKLTLSLLDQENFTKHYSDTFKPDPKSPCFQRPILDSNIASGSPKFYSISHLSFNSIYYKNDTIYIKITV 427 The following BLAST results are available for this feature:
BLAST of TNF receptor-associated factor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TNF receptor-associated factor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002783 ID=SMED30002783|Name=TNF receptor-associated factor|organism=Schmidtea mediterranea sexual|type=transcript|length=4234bpback to top protein sequence of SMED30002783-orf-1 >SMED30002783-orf-1 ID=SMED30002783-orf-1|Name=SMED30002783-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=479bp MPLKFIYEYIKPKKKINFYFYPFQSLNSKLYNCHPEVTEQGFQFLKKVPSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
