Lipase

Overview
NameLipase
Smed IDSMED30002769
Length (bp)455
Neoblast Clusters

Zeng et. al., 2018




 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30002769

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30002769h1SMcG0006863 SmedASXL_006721SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30002769h1SMcG0006863 SmedASXL_006720SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
parenchymaSMED30002769h1SMcG0006863 dd_Smed_v4_7967_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
prepharyngeal regionSMED30002769h1SMcG0006863 dd_Smed_v6_7967_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
prepharyngeal regionSMED30002769h1SMcG0006863 dd_Smed_v6_9731_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Lipase vs. Ensembl Human
Match: LIPM (lipase family member M [Source:HGNC Symbol;Acc:HGNC:23455])

HSP 1 Score: 143.28 bits (360), Expect = 3.588e-41
Identity = 69/120 (57.50%), Postives = 87/120 (72.50%), Query Frame = 3
Query:   99 SIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGL-KNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            +++ EA MN+SEII+  GYP E + V TEDGYILS+ RIP GL +   T SRPVVLLQHGL+  +  ++SN P  SLGFILAD GFDVW+ NSRGN +S  H   S ++ EFW F++DEM
Sbjct:   40 AVDPEAFMNISEIIQHQGYPCEEYEVATEDGYILSVNRIPRGLVQPKKTGSRPVVLLQHGLVGGASNWISNLPNNSLGFILADAGFDVWMGNSRGNAWSRKHKTLSIDQDEFWAFSYDEM 159          
BLAST of Lipase vs. Ensembl Human
Match: LIPA (lipase A, lysosomal acid type [Source:HGNC Symbol;Acc:HGNC:6617])

HSP 1 Score: 135.191 bits (339), Expect = 5.411e-40
Identity = 74/149 (49.66%), Postives = 94/149 (63.09%), Query Frame = 3
Query:   30 NLDFVGLSFFILFLGNGLLHAEPS------IEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDS-RPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
             + F+GL   ++      LH+E S      ++ E  MNVSEII  +G+P E + V TEDGYIL L RIP+G KN S    +PVV LQHGLL  S  +V+N    SLGFILAD GFDVW+ NSRGN +S  H   S ++ EFW F++DEM
Sbjct:    2 KMRFLGLVVCLVLW---TLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEM 147          
BLAST of Lipase vs. Ensembl Human
Match: LIPA (lipase A, lysosomal acid type [Source:HGNC Symbol;Acc:HGNC:6617])

HSP 1 Score: 135.191 bits (339), Expect = 3.492e-39
Identity = 74/148 (50.00%), Postives = 94/148 (63.51%), Query Frame = 3
Query:   33 LDFVGLSFFILFLGNGLLHAEPS------IEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDS-RPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            + F+GL   ++      LH+E S      ++ E  MNVSEII  +G+P E + V TEDGYIL L RIP+G KN S    +PVV LQHGLL  S  +V+N    SLGFILAD GFDVW+ NSRGN +S  H   S ++ EFW F++DEM
Sbjct:    3 MRFLGLVVCLVLW---TLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEM 147          
BLAST of Lipase vs. Ensembl Human
Match: LIPF (lipase F, gastric type [Source:HGNC Symbol;Acc:HGNC:6622])

HSP 1 Score: 135.961 bits (341), Expect = 1.671e-38
Identity = 65/116 (56.03%), Postives = 84/116 (72.41%), Query Frame = 3
Query:  111 EAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNT-STDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            E  MN+S++I  +GYP E + V TEDGYIL + RIPYG KN+ +T  RPVV LQHGLL S+  ++SN P  SL FILAD G+DVWL NSRGN ++  ++ YS +  EFW F++DEM
Sbjct:   30 EVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDSVEFWAFSFDEM 145          
BLAST of Lipase vs. Ensembl Human
Match: LIPF (lipase F, gastric type [Source:HGNC Symbol;Acc:HGNC:6622])

HSP 1 Score: 135.961 bits (341), Expect = 1.941e-38
Identity = 65/116 (56.03%), Postives = 84/116 (72.41%), Query Frame = 3
Query:  111 EAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNT-STDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            E  MN+S++I  +GYP E + V TEDGYIL + RIPYG KN+ +T  RPVV LQHGLL S+  ++SN P  SL FILAD G+DVWL NSRGN ++  ++ YS +  EFW F++DEM
Sbjct:   40 EVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDSVEFWAFSFDEM 155          
BLAST of Lipase vs. Ensembl Celegans
Match: lipl-2 (Lipase [Source:UniProtKB/TrEMBL;Acc:Q20449])

HSP 1 Score: 137.502 bits (345), Expect = 1.712e-39
Identity = 67/148 (45.27%), Postives = 90/148 (60.81%), Query Frame = 3
Query:   18 FMKRNLDFVGLSFFILFLGNGLLHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTS--TDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            F+ +    +  SF +L      ++A P  + E  MN S+II+ +GY  E+H+VTTEDGYIL +QRIPYG  + +     RPV+LLQHGLL  +  +V N P +S  F+ AD GFDVWL N RG  Y   + K   +E  FW F+WDEM
Sbjct:    3 FLAQITCLICTSFLLL----QTINAHPDDDPELNMNTSQIIERWGYKAEVHTVTTEDGYILQMQRIPYGKTSVTWPNGKRPVILLQHGLLACASDWVDNLPTQSAAFVFADAGFDVWLGNVRGTTYGRKNTKLDPSETAFWQFSWDEM 146          
BLAST of Lipase vs. Ensembl Celegans
Match: lipl-6 (LIPase Like [Source:UniProtKB/TrEMBL;Acc:E2S7J2])

HSP 1 Score: 135.191 bits (339), Expect = 1.171e-37
Identity = 62/123 (50.41%), Postives = 83/123 (67.48%), Query Frame = 3
Query:   99 SIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDS----RPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            +I+ EA M+V EII  +GYP+E H V T DGYIL+L RIP+G   TS  +    +PVV LQHGLL +S  ++ N P +S G+I AD G+DVWL N RGN YS  H + +  ++ FW F+W+EM
Sbjct:  173 TIDPEALMDVPEIITHWGYPVETHKVVTVDGYILTLHRIPHGKNETSKSASKTPKPVVFLQHGLLCTSSIWLLNLPRQSAGYIFADQGYDVWLGNMRGNTYSKEHTRMTSADRRFWKFSWEEM 295          
BLAST of Lipase vs. Ensembl Celegans
Match: lipl-4 (Lipase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUZ3])

HSP 1 Score: 130.183 bits (326), Expect = 1.373e-36
Identity = 62/124 (50.00%), Postives = 90/124 (72.58%), Query Frame = 3
Query:   99 SIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLK-NTSTD---SRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQ-EFWDFTWDEM 455
            S++ E  ++  E+IKS+GY +E+++ TT+DG+IL L RIPYG +  TS+D   SRPV+ LQHG L SSF +V+N P +S GF+ AD GFDVWL N RGN YS  H+  + ++  +FWD++WD++
Sbjct:   27 SVDLEFYLDTPELIKSWGYSVEIYNTTTKDGFILELHRIPYGREVPTSSDVNNSRPVIFLQHGFLCSSFDWVANSPHQSAGFVFADAGFDVWLGNFRGNTYSRKHVSLNPDKDPKFWDWSWDQI 150          
BLAST of Lipase vs. Ensembl Celegans
Match: lipl-5 (Lipase [Source:UniProtKB/TrEMBL;Acc:O61866])

HSP 1 Score: 125.561 bits (314), Expect = 5.830e-35
Identity = 59/125 (47.20%), Postives = 79/125 (63.20%), Query Frame = 3
Query:   87 HAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTS--TDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            H +P    E  M   +II+ +GYP  +++V T+DGYIL + RIP+G  N +     RPVV +QHGLL +S  +V N P++S GF+ AD GFDVWL N RGN YS  H     +   FWD++WDEM
Sbjct:   20 HGDP----ELHMTTPQIIERWGYPAMIYTVATDDGYILEMHRIPFGKTNVTWPNGKRPVVFMQHGLLCASSDWVVNLPDQSAGFLFADAGFDVWLGNMRGNTYSMKHKDLKPSHSAFWDWSWDEM 140          
BLAST of Lipase vs. Ensembl Celegans
Match: lipl-5 (Lipase [Source:UniProtKB/TrEMBL;Acc:O61866])

HSP 1 Score: 125.561 bits (314), Expect = 5.830e-35
Identity = 59/125 (47.20%), Postives = 79/125 (63.20%), Query Frame = 3
Query:   87 HAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTS--TDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            H +P    E  M   +II+ +GYP  +++V T+DGYIL + RIP+G  N +     RPVV +QHGLL +S  +V N P++S GF+ AD GFDVWL N RGN YS  H     +   FWD++WDEM
Sbjct:   20 HGDP----ELHMTTPQIIERWGYPAMIYTVATDDGYILEMHRIPFGKTNVTWPNGKRPVVFMQHGLLCASSDWVVNLPDQSAGFLFADAGFDVWLGNMRGNTYSMKHKDLKPSHSAFWDWSWDEM 140          
BLAST of Lipase vs. Ensembl Fly
Match: Lip4 (gene:FBgn0032264 transcript:FBtr0304119)

HSP 1 Score: 131.339 bits (329), Expect = 6.472e-37
Identity = 63/125 (50.40%), Postives = 85/125 (68.00%), Query Frame = 3
Query:   90 AEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRP---VVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
             +P+I+E++ +N   +IK YGYP E H++ T+DGYIL+L RI          +RP    VLL HGLLDSS T+V  GP K LG++L D G+DVW++N RGN YS  H+KYS +  +FWDFT+ EM
Sbjct:   59 VDPNIQEDSHLNTYSLIKKYGYPAENHTLETDDGYILTLHRI----------ARPGATPVLLVHGLLDSSATWVMMGPNKGLGYLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAKFWDFTFHEM 173          
BLAST of Lipase vs. Ensembl Fly
Match: Lip4 (gene:FBgn0032264 transcript:FBtr0080093)

HSP 1 Score: 131.339 bits (329), Expect = 7.395e-37
Identity = 63/125 (50.40%), Postives = 85/125 (68.00%), Query Frame = 3
Query:   90 AEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRP---VVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
             +P+I+E++ +N   +IK YGYP E H++ T+DGYIL+L RI          +RP    VLL HGLLDSS T+V  GP K LG++L D G+DVW++N RGN YS  H+KYS +  +FWDFT+ EM
Sbjct:   59 VDPNIQEDSHLNTYSLIKKYGYPAENHTLETDDGYILTLHRI----------ARPGATPVLLVHGLLDSSATWVMMGPNKGLGYLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAKFWDFTFHEM 173          
BLAST of Lipase vs. Ensembl Fly
Match: Lip4 (gene:FBgn0032264 transcript:FBtr0331672)

HSP 1 Score: 131.724 bits (330), Expect = 7.782e-37
Identity = 71/155 (45.81%), Postives = 98/155 (63.23%), Query Frame = 3
Query:    9 LFNFMKRNLDFVGLSFFI---LFLGNGLLHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRP---VVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            LFN   +   F+G S  +   + L N +   +P+I+E++ +N   +IK YGYP E H++ T+DGYIL+L RI          +RP    VLL HGLLDSS T+V  GP K LG++L D G+DVW++N RGN YS  H+KYS +  +FWDFT+ EM
Sbjct:   46 LFNVNFKTPTFLGRSVAVDSNVRLENDV---DPNIQEDSHLNTYSLIKKYGYPAENHTLETDDGYILTLHRI----------ARPGATPVLLVHGLLDSSATWVMMGPNKGLGYLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAKFWDFTFHEM 187          
BLAST of Lipase vs. Ensembl Fly
Match: mag (gene:FBgn0036996 transcript:FBtr0078196)

HSP 1 Score: 125.946 bits (315), Expect = 4.485e-35
Identity = 61/125 (48.80%), Postives = 85/125 (68.00%), Query Frame = 3
Query:  102 IEEEAKMNVSEIIKS------YGYPLEMHSVTTEDGYILSLQRIPYGLK-NTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            + E++   +SEI+KS      +GYP E H VTT+DGY+L+L RIPY  K     + RP +LLQHGL  +S  ++S+GP+ SL ++LAD G+DVWL N+RGNIYS ++I  S N  +FW F W E+
Sbjct:   18 LAEKSDYCLSEIVKSDERIRSHGYPTETHEVTTQDGYVLTLFRIPYSHKLKNQNEKRPPILLQHGLFSNSDCWLSSGPDNSLAYLLADAGYDVWLGNARGNIYSRNNIIISLNSHKFWHFDWHEI 142          
BLAST of Lipase vs. Ensembl Fly
Match: CG18302 (gene:FBgn0032266 transcript:FBtr0080095)

HSP 1 Score: 123.635 bits (309), Expect = 3.783e-34
Identity = 60/139 (43.17%), Postives = 86/139 (61.87%), Query Frame = 3
Query:   39 FVGLSFFILFLGNGLLHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
             + L  F       L+  + +I E+A +   ++IK YGYP E H +  +DG++L+  RIP          +PV LL HGLLDSS  YV  GPE+SLGF+L+D G+DVWL N+RGN YS  H +Y + + +FWDF++ E+
Sbjct:   14 LISLFIFCDTASGDLIKVDKTILEDANLITPDLIKKYGYPAETHKIQAKDGFVLTAHRIP------KPGGQPV-LLVHGLLDSSVAYVILGPERSLGFLLSDMGYDVWLLNTRGNRYSRKHKRYHRYQPQFWDFSFHEL 145          
BLAST of Lipase vs. Ensembl Zebrafish
Match: lipf (lipase, gastric [Source:ZFIN;Acc:ZDB-GENE-040426-2737])

HSP 1 Score: 142.895 bits (359), Expect = 2.262e-41
Identity = 63/118 (53.39%), Postives = 85/118 (72.03%), Query Frame = 3
Query:  102 IEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            ++ E  MN+SEII+ +GYP E   V TEDGYILS+ RIP+G+KN + + +PVV LQHGLL +   +V+N P  SLGF+LAD GFDVW+ NSRGN +S  H+     ++E+W F+ DEM
Sbjct:   28 LDPEVNMNISEIIRHWGYPAEEFEVVTEDGYILSINRIPHGVKNKNEEVKPVVFLQHGLLAAGSNWVTNLPNNSLGFVLADAGFDVWIGNSRGNTWSCKHVSLDPRQKEYWKFSHDEM 145          
BLAST of Lipase vs. Ensembl Zebrafish
Match: lipf (lipase, gastric [Source:ZFIN;Acc:ZDB-GENE-040426-2737])

HSP 1 Score: 142.895 bits (359), Expect = 2.262e-41
Identity = 63/118 (53.39%), Postives = 85/118 (72.03%), Query Frame = 3
Query:  102 IEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            ++ E  MN+SEII+ +GYP E   V TEDGYILS+ RIP+G+KN + + +PVV LQHGLL +   +V+N P  SLGF+LAD GFDVW+ NSRGN +S  H+     ++E+W F+ DEM
Sbjct:   28 LDPEVNMNISEIIRHWGYPAEEFEVVTEDGYILSINRIPHGVKNKNEEVKPVVFLQHGLLAAGSNWVTNLPNNSLGFVLADAGFDVWIGNSRGNTWSCKHVSLDPRQKEYWKFSHDEM 145          
BLAST of Lipase vs. Ensembl Xenopus
Match: lipa (lipase A, lysosomal acid, cholesterol esterase [Source:NCBI gene;Acc:548564])

HSP 1 Score: 136.346 bits (342), Expect = 2.621e-38
Identity = 64/119 (53.78%), Postives = 84/119 (70.59%), Query Frame = 3
Query:   99 SIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            S + EA MN+SE+I+  GYP E + V TEDGYILS+ RIP+G+K  S   +PVV LQHGLL     +V+N    SLGFILAD G+DVW+ NSRGN +S  H   S +++EFW F++DE+
Sbjct:   82 SADPEATMNISELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEEFWAFSYDEL 200          
BLAST of Lipase vs. Ensembl Xenopus
Match: lipa (lipase A, lysosomal acid, cholesterol esterase [Source:NCBI gene;Acc:548564])

HSP 1 Score: 125.946 bits (315), Expect = 6.144e-35
Identity = 60/116 (51.72%), Postives = 81/116 (69.83%), Query Frame = 3
Query:  111 EAKMNV-SEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            + +M+  SE+I+  GYP E + V TEDGYILS+ RIP+G+K  S   +PVV LQHGLL     +V+N    SLGFILAD G+DVW+ NSRGN +S  H   S +++EFW F++DE+
Sbjct:    3 DCRMHCPSELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEEFWAFSYDEL 118          
BLAST of Lipase vs. Ensembl Xenopus
Match: lipa (lipase A, lysosomal acid, cholesterol esterase [Source:NCBI gene;Acc:548564])

HSP 1 Score: 125.561 bits (314), Expect = 8.188e-35
Identity = 59/114 (51.75%), Postives = 78/114 (68.42%), Query Frame = 3
Query:  114 AKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            A   + E+I+  GYP E + V TEDGYILS+ RIP+G+K  S   +PVV LQHGLL     +V+N    SLGFILAD G+DVW+ NSRGN +S  H   S +++EFW F++DE+
Sbjct:    7 ASYQIFELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEEFWAFSYDEL 120          
BLAST of Lipase vs. Ensembl Xenopus
Match: lipa (lipase A, lysosomal acid, cholesterol esterase [Source:NCBI gene;Acc:548564])

HSP 1 Score: 125.561 bits (314), Expect = 1.144e-34
Identity = 59/112 (52.68%), Postives = 79/112 (70.54%), Query Frame = 3
Query:  120 MNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            ++ SE+I+  GYP E + V TEDGYILS+ RIP+G+K  S   +PVV LQHGLL     +V+N    SLGFILAD G+DVW+ NSRGN +S  H   S +++EFW F++DE+
Sbjct:   30 ISSSELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEEFWAFSYDEL 141          
BLAST of Lipase vs. Ensembl Xenopus
Match: lipa (lipase A, lysosomal acid, cholesterol esterase [Source:NCBI gene;Acc:548564])

HSP 1 Score: 124.02 bits (310), Expect = 2.339e-34
Identity = 58/108 (53.70%), Postives = 76/108 (70.37%), Query Frame = 3
Query:  132 EIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            E+I+  GYP E + V TEDGYILS+ RIP+G+K  S   +PVV LQHGLL     +V+N    SLGFILAD G+DVW+ NSRGN +S  H   S +++EFW F++DE+
Sbjct:    3 ELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEEFWAFSYDEL 110          
BLAST of Lipase vs. Ensembl Mouse
Match: Lipm (lipase, family member M [Source:MGI Symbol;Acc:MGI:1926003])

HSP 1 Score: 139.043 bits (349), Expect = 9.739e-40
Identity = 70/120 (58.33%), Postives = 84/120 (70.00%), Query Frame = 3
Query:   99 SIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTD-SRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            + + EA MNVSEIIK  GYP E + V TEDGYILS+ RIP G      + SRPVVLLQHGLL  +  ++SN P  SLGFILAD GFDVW+ NSRGN +S  H   S ++ EFW F++DEM
Sbjct:   40 AADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQTRLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEM 159          
BLAST of Lipase vs. Ensembl Mouse
Match: Lipf (lipase, gastric [Source:MGI Symbol;Acc:MGI:1914967])

HSP 1 Score: 134.035 bits (336), Expect = 6.005e-38
Identity = 64/116 (55.17%), Postives = 83/116 (71.55%), Query Frame = 3
Query:  111 EAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNT-STDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            EA MNVS++I  +GYP E + V TEDGYIL + RIPYG KN+ +   RPV  LQHGL+ S+  +++N P  SL FILAD G+DVWL NSRGN +S  ++ YS +  EFW F++DEM
Sbjct:   29 EANMNVSQMITYWGYPSEEYEVVTEDGYILGVYRIPYGKKNSENIGKRPVAYLQHGLIASATNWITNLPNNSLAFILADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEM 144          
BLAST of Lipase vs. Ensembl Mouse
Match: Lipa (lysosomal acid lipase A [Source:MGI Symbol;Acc:MGI:96789])

HSP 1 Score: 132.494 bits (332), Expect = 2.493e-37
Identity = 67/120 (55.83%), Postives = 82/120 (68.33%), Query Frame = 3
Query:   99 SIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNT-STDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            +++ E  MNV+EII  +GYP E HSV T DGYILS+ RIP G KN      RPVV LQHGLL  S  +V+N    SLGF+LAD GFDVW+ NSRGN +S  H   S ++ EFW F++DEM
Sbjct:   26 AVDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGLLADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEM 145          
BLAST of Lipase vs. Ensembl Mouse
Match: Lipa (lysosomal acid lipase A [Source:MGI Symbol;Acc:MGI:96789])

HSP 1 Score: 132.494 bits (332), Expect = 2.493e-37
Identity = 67/120 (55.83%), Postives = 82/120 (68.33%), Query Frame = 3
Query:   99 SIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNT-STDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            +++ E  MNV+EII  +GYP E HSV T DGYILS+ RIP G KN      RPVV LQHGLL  S  +V+N    SLGF+LAD GFDVW+ NSRGN +S  H   S ++ EFW F++DEM
Sbjct:   26 AVDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGLLADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEM 145          
BLAST of Lipase vs. Ensembl Mouse
Match: Lipk (lipase, family member K [Source:MGI Symbol;Acc:MGI:2679259])

HSP 1 Score: 131.724 bits (330), Expect = 4.334e-37
Identity = 62/117 (52.99%), Postives = 81/117 (69.23%), Query Frame = 3
Query:  111 EAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRP--VVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            EA MN+SE+I  +GYP E H V TEDGYIL   RIP+G K  S  + P  VV LQHGL+ S+  ++ N P  SL F+LAD+G+DVWL NSRGN +S +H++ S    ++W F+WDEM
Sbjct:   29 EANMNISELISYWGYPYEKHDVITEDGYILGTYRIPHG-KGCSRKTAPKAVVYLQHGLIASANNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRNHLRLSPKSPQYWAFSWDEM 144          
BLAST of Lipase vs. UniProt/SwissProt
Match: sp|Q5VYY2|LIPM_HUMAN (Lipase member M OS=Homo sapiens OX=9606 GN=LIPM PE=2 SV=2)

HSP 1 Score: 143.28 bits (360), Expect = 1.723e-40
Identity = 69/120 (57.50%), Postives = 87/120 (72.50%), Query Frame = 3
Query:   99 SIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGL-KNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            +++ EA MN+SEII+  GYP E + V TEDGYILS+ RIP GL +   T SRPVVLLQHGL+  +  ++SN P  SLGFILAD GFDVW+ NSRGN +S  H   S ++ EFW F++DEM
Sbjct:   40 AVDPEAFMNISEIIQHQGYPCEEYEVATEDGYILSVNRIPRGLVQPKKTGSRPVVLLQHGLVGGASNWISNLPNNSLGFILADAGFDVWMGNSRGNAWSRKHKTLSIDQDEFWAFSYDEM 159          
BLAST of Lipase vs. UniProt/SwissProt
Match: sp|Q29458|LIPG_BOVIN (Gastric triacylglycerol lipase OS=Bos taurus OX=9913 GN=LIPF PE=1 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 1.284e-39
Identity = 66/116 (56.90%), Postives = 84/116 (72.41%), Query Frame = 3
Query:  111 EAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTS-TDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            EA MNVS++I  +GYP EMH V T DGYIL + RIP+G  N +    RPVV LQHGLL S+  ++SN P+ SLGF+LAD G+DVWL NSRGN ++  H+ YS +  EFW F++DEM
Sbjct:   29 EASMNVSQMISYWGYPSEMHKVITADGYILQVYRIPHGKNNANHLGQRPVVFLQHGLLGSATNWISNLPKNSLGFLLADAGYDVWLGNSRGNTWAQEHLYYSPDSPEFWAFSFDEM 144          
BLAST of Lipase vs. UniProt/SwissProt
Match: sp|Q8K2A6|LIPM_MOUSE (Lipase member M OS=Mus musculus OX=10090 GN=Lipm PE=2 SV=1)

HSP 1 Score: 139.043 bits (349), Expect = 6.812e-39
Identity = 70/120 (58.33%), Postives = 84/120 (70.00%), Query Frame = 3
Query:   99 SIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTD-SRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            + + EA MNVSEIIK  GYP E + V TEDGYILS+ RIP G      + SRPVVLLQHGLL  +  ++SN P  SLGFILAD GFDVW+ NSRGN +S  H   S ++ EFW F++DEM
Sbjct:   40 AADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQTRLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEM 159          
BLAST of Lipase vs. UniProt/SwissProt
Match: sp|P07098|LIPG_HUMAN (Gastric triacylglycerol lipase OS=Homo sapiens OX=9606 GN=LIPF PE=1 SV=1)

HSP 1 Score: 135.961 bits (341), Expect = 8.024e-38
Identity = 65/116 (56.03%), Postives = 84/116 (72.41%), Query Frame = 3
Query:  111 EAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNT-STDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            E  MN+S++I  +GYP E + V TEDGYIL + RIPYG KN+ +T  RPVV LQHGLL S+  ++SN P  SL FILAD G+DVWL NSRGN ++  ++ YS +  EFW F++DEM
Sbjct:   30 EVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDSVEFWAFSFDEM 145          
BLAST of Lipase vs. UniProt/SwissProt
Match: sp|Q4R4S5|LICH_MACFA (Lysosomal acid lipase/cholesteryl ester hydrolase OS=Macaca fascicularis OX=9541 GN=LIPA PE=2 SV=1)

HSP 1 Score: 134.806 bits (338), Expect = 2.152e-37
Identity = 75/148 (50.68%), Postives = 94/148 (63.51%), Query Frame = 3
Query:   33 LDFVGLSFFILFLGNGLLHAEPS------IEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDS-RPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            + F+GL   ++ L    LH+E S      +  E  MNVSEII  +G+P E + V TEDGYIL L RIP+G KN S    +PVV LQHGLL  S  +V+N    SLGFILAD GFDVW+ NSRGN +S  H   S ++ EFW F++DEM
Sbjct:    3 MRFLGL---VVCLVLWTLHSEASGGKLTAVNPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEM 147          
BLAST of Lipase vs. TrEMBL
Match: A0A212CNN2 (Uncharacterized protein (Fragment) OS=Cervus elaphus hippelaphus OX=46360 GN=Celaphus_00008443 PE=4 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 6.458e-41
Identity = 73/137 (53.28%), Postives = 95/137 (69.34%), Query Frame = 3
Query:   57 FILFLG--NGLLHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDS--RPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            FIL LG  +G    + S+  EA MN+S+II  +GYP E + +TTEDGYILSL RIPYG  N+  +S  R VV LQHGLL S+ +++SN P  SLGF+LAD G+DVW+ NSRG  +S  H+    N +EFW F++DEM
Sbjct:    3 FILILGTTHGAFRKQRSVNPEASMNISQIISYWGYPDEEYDITTEDGYILSLYRIPYGKTNSENNSVQRLVVYLQHGLLTSASSWISNLPNNSLGFLLADAGYDVWMGNSRGTTWSRKHLYLKTNSKEFWAFSFDEM 139          
BLAST of Lipase vs. TrEMBL
Match: A0A5N5T4Y3 (Lipase 1 OS=Armadillidium nasatum OX=96803 GN=Lip1 PE=4 SV=1)

HSP 1 Score: 144.821 bits (364), Expect = 7.126e-41
Identity = 66/121 (54.55%), Postives = 91/121 (75.21%), Query Frame = 3
Query:   99 SIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSK--NEQEFWDFTWDEM 455
            SI +  ++ V EII+S+GYP E H VTTEDGYIL L RIPYG+   S ++RPV LLQHGLL SSF ++S+ P+++L ++LAD G+DVWL N+RGN+YS +H       +++EFW FT+DE+
Sbjct:   23 SIYDYEELTVPEIIQSFGYPAETHHVTTEDGYILELHRIPYGIDGPSEEARPVALLQHGLLVSSFDWISDRPDRALAYMLADAGYDVWLMNARGNLYSRNHTTLDPDVDKEEFWGFTYDEI 143          
BLAST of Lipase vs. TrEMBL
Match: A0A2J7QG21 (Lipase 3 OS=Cryptotermes secundus OX=105785 GN=Lip3_3 PE=4 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 2.028e-40
Identity = 67/130 (51.54%), Postives = 92/130 (70.77%), Query Frame = 3
Query:   81 LLHAEPSIE-----EEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            LL+  PS+E      +  +N  E+I+ YGYP E+H+VTTED YIL++ RIPY  K+ +  ++PVV LQHG+L SS  ++  GPE SLG++LAD GFDVWL N+RGN YS  H+  S ++ +FWDF+W EM
Sbjct:   51 LLNLIPSLENNNGNPDQYLNTPELIEKYGYPAEIHTVTTEDSYILTVHRIPYSPKSPAAPNKPVVFLQHGILSSSADWIILGPENSLGYLLADAGFDVWLGNARGNTYSKKHLSLSTSDSKFWDFSWHEM 180          
BLAST of Lipase vs. TrEMBL
Match: A0A016WCI6 (Abhydro_lipase domain-containing protein OS=Ancylostoma ceylanicum OX=53326 GN=Acey_s0783.g2328 PE=4 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 2.639e-40
Identity = 70/137 (51.09%), Postives = 89/137 (64.96%), Query Frame = 3
Query:   48 LSFFILFLGNGLLHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTS-TDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            L  F++ L     +A    + E KM   +II+ +GYP E+++VTTEDGYIL L RIPYG  +   T  RPVV +QHGL  SS  +V+N P++S GFI AD GFDVWL N RGN YS  HI  S    +FW++TWDEM
Sbjct:    3 LCSFLVALAAITTYARKHEDPECKMTTPQIIEHWGYPAEIYTVTTEDGYILELHRIPYGKNDAKPTSPRPVVFMQHGLECSSSNWVTNLPDESAGFIFADAGFDVWLGNMRGNTYSTKHINLSPKHDKFWEWTWDEM 139          
BLAST of Lipase vs. TrEMBL
Match: A0A5N5T4S5 (Lipase 3 (Fragment) OS=Armadillidium nasatum OX=96803 GN=Lip3_4 PE=4 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 2.659e-40
Identity = 64/114 (56.14%), Postives = 89/114 (78.07%), Query Frame = 3
Query:  120 MNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYS--KNEQEFWDFTWDEM 455
            + V EII+S+GYP+E+H VTTEDGYIL L RIPYG+  +S ++RPV LLQHGLL SSF ++S+ P+++L ++LAD G+DVWL N+RGN YS +H       +++EFW FT+DE+
Sbjct:    6 LTVPEIIQSFGYPVEIHHVTTEDGYILELHRIPYGIDGSSEEARPVALLQHGLLVSSFDWISDRPDRALAYLLADAGYDVWLMNARGNYYSRNHTTLDPVADKEEFWAFTYDEI 119          
BLAST of Lipase vs. Ensembl Cavefish
Match: lipf (lysosomal acid lipase/cholesteryl ester hydrolase-like [Source:NCBI gene;Acc:103040858])

HSP 1 Score: 147.132 bits (370), Expect = 4.313e-43
Identity = 67/120 (55.83%), Postives = 88/120 (73.33%), Query Frame = 3
Query:  102 IEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDS--RPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            ++ E  MN+SEII+ +GYP E + V TEDGYILS+ RIPYG+KN  + +  RPVV LQHGLL +   +V+N P  SLGF+LAD GFDVWL NSRGN +S  H+  S ++ E+W+F+ DEM
Sbjct:   26 VDPEVNMNISEIIRYWGYPAEEYEVVTEDGYILSINRIPYGVKNKDSQAAPRPVVFLQHGLLAAGSNWVTNLPNTSLGFVLADAGFDVWLGNSRGNTWSRKHVSLSPDQNEYWEFSHDEM 145          
BLAST of Lipase vs. Ensembl Cavefish
Match: lipf (lysosomal acid lipase/cholesteryl ester hydrolase-like [Source:NCBI gene;Acc:103023710])

HSP 1 Score: 146.362 bits (368), Expect = 9.356e-43
Identity = 67/131 (51.15%), Postives = 93/131 (70.99%), Query Frame = 3
Query:   69 LGNGLLHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKN--TSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            L +G L     ++ E  MN+SEII+ +GYP E + V TEDGYILS+ RIP+G+KN  +  D +PVV LQHGLL ++  +V+N P  SLG++LAD GFDVWL NSRGN +S  H+  S+++ E+W F+ DE+
Sbjct:   15 LAHGWLFWRRRVDPEIHMNISEIIRYWGYPAEEYEVVTEDGYILSINRIPHGIKNQDSRADPKPVVFLQHGLLAAASNWVTNLPNTSLGYLLADAGFDVWLGNSRGNTWSRKHVSLSRDQNEYWRFSRDEL 145          
BLAST of Lipase vs. Ensembl Sea Lamprey
Match: lipf (lipase, gastric [Source:ZFIN;Acc:ZDB-GENE-040426-2737])

HSP 1 Score: 128.257 bits (321), Expect = 1.801e-36
Identity = 69/160 (43.12%), Postives = 96/160 (60.00%), Query Frame = 3
Query:    6 ILFNFMKRNLDFVGLSFFILFLGNGLL--------HAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTS--TDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            + F  ++  +  V L   +L  G G +        H +   + E  MN+SE+I S GYP   + V T DG+ILS+ RIP GLK+ +  T  RP VLLQHGLL     +VSN    SLGFILAD G+DVW+ NSRGN +S+ H   + +++EFW +++DEM
Sbjct:    1 LCFVLIRNMVLIVALHVTLLLFGVGFVSGRMLPDQHNDLRSDPEIYMNISELISSKGYPNVEYKVETADGFILSVNRIPRGLKDNTAGTAVRPAVLLQHGLLAGGSNWVSNFAHDSLGFILADAGYDVWIGNSRGNTWSHHHRTLTPDQEEFWAWSYDEM 160          
BLAST of Lipase vs. Ensembl Sea Lamprey
Match: lipf (lipase, gastric [Source:ZFIN;Acc:ZDB-GENE-040426-2737])

HSP 1 Score: 117.857 bits (294), Expect = 1.586e-33
Identity = 59/120 (49.17%), Postives = 80/120 (66.67%), Query Frame = 3
Query:   84 LHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFT 443
            +H +   + E  MN+SE+I S GYP   + V T DG+ILS+ RIP GLK+++   RP VLLQHGLL     +VSN    SLGFILAD G+DVW+ NSRGN  S+ H   + +++EFW ++
Sbjct:   15 VHNDLRSDPEMYMNISELISSKGYPNVEYKVETADGFILSVNRIPRGLKHSTAAVRPAVLLQHGLLAGGSNWVSNFAHDSLGFILADAGYDVWIGNSRGNT-SHHHRALTPDQEEFWAWS 133          
BLAST of Lipase vs. Ensembl Yeast
Match: TGL1 (Steryl ester hydrolase; one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes [Source:SGD;Acc:S000001623])

HSP 1 Score: 86.6557 bits (213), Expect = 4.191e-21
Identity = 50/121 (41.32%), Postives = 69/121 (57.02%), Query Frame = 3
Query:   99 SIEEEAKM--NVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSN-GPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDE 452
            +IEE+ +    + E+   +   +E H V TED YIL+L RIP   KN   +   VV L HGLL  S  +  N    K+L F+L D G+DVW+ N+RGN YS +H+       +FWDF+ DE
Sbjct:   55 TIEEKLRSAPTIHEMCAIFDISVEDHLVRTEDNYILTLHRIPPISKNRFNNK--VVYLHHGLLMCSDVWCCNIERHKNLPFVLHDLGYDVWMGNNRGNKYSTAHLNKPPKSNKFWDFSIDE 173          
BLAST of Lipase vs. Ensembl Yeast
Match: YEH1 (Steryl ester hydrolase; one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes; YEH1 has a paralog, YEH2, that arose from the whole genome duplication [Source:SGD;Acc:S000003935])

HSP 1 Score: 60.4622 bits (145), Expect = 5.245e-12
Identity = 31/80 (38.75%), Postives = 48/80 (60.00%), Query Frame = 3
Query:  144 SYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDS--RPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSR 377
             Y   +E   + TEDG+++ L  +    + T +D   RP +L+ HGLL SS ++ SNG  KSL + L  +G+D+WL N+R
Sbjct:  184 QYNIQIEEFRLETEDGFVIDLWHLIPKYRTTDSDKKKRPPILMLHGLLQSSGSFASNG-RKSLAYFLYQSGYDIWLGNNR 262          
BLAST of Lipase vs. Ensembl Yeast
Match: YEH2 (Steryl ester hydrolase; catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism; YEH2 has a paralog, YEH1, that arose from the whole genome duplication [Source:SGD;Acc:S000004010])

HSP 1 Score: 60.077 bits (144), Expect = 6.985e-12
Identity = 38/107 (35.51%), Postives = 59/107 (55.14%), Query Frame = 3
Query:  141 KSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTD-SRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQ-EFWDFTWDEM 455
            K YG  +E   V T+DG+I+ L      L +   +  R  +LL HGLL S   + S+G  KSL + L ++GFDVWL N+R  + +  ++K   N+  + WD+   +M
Sbjct:  155 KEYGIDIEEFEVETDDGFIIDLWHFKSRLNDGVEEVKREPILLLHGLLQSCGAFASSG-RKSLAYFLYESGFDVWLGNNRCGLNAKWNMKKLGNDHSKKWDWDMHQM 260          
BLAST of Lipase vs. Ensembl Nematostella
Match: EDO38398 (Lipase [Source:UniProtKB/TrEMBL;Acc:A7SCY7])

HSP 1 Score: 138.272 bits (347), Expect = 5.122e-40
Identity = 70/146 (47.95%), Postives = 94/146 (64.38%), Query Frame = 3
Query:   42 VGLSFFILFLGNGLLH-----AEPS---IEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNT-STDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDE 452
            V     ++ LGN L         P    ++ +   NVS++I + G+P+E H V T+DGYILS+QRIP+G K   S   RPVV LQHGLL  S  +V +    SLG+ILADNG+DVWL N RGN YS SH+KY+  ++EFWDF+++E
Sbjct:    3 VSFCLLVVLLGNQLCCLLAKGTRPKWGPVDPDVNRNVSQLIHNRGFPVEEHDVITKDGYILSVQRIPHGRKGRESPGPRPVVFLQHGLLADSSCFVQSWEYDSLGYILADNGYDVWLGNIRGNRYSRSHVKYNHKQREFWDFSFEE 148          
BLAST of Lipase vs. Ensembl Nematostella
Match: EDO40744 (Lipase [Source:UniProtKB/TrEMBL;Acc:A7S6G4])

HSP 1 Score: 138.272 bits (347), Expect = 6.841e-40
Identity = 65/123 (52.85%), Postives = 86/123 (69.92%), Query Frame = 3
Query:   93 EPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDS--RPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            EP  + +   N S++I++ GYP+E H VTT DG+IL+LQRIP+G       S  +PVV LQHGLL  S  +V N P  SLG+ILAD GFDVWL N RGN YS +H+K++K+  +FWD+TW +M
Sbjct:   27 EPPRDPDIDRNASQLIRNRGYPVEEHYVTTSDGFILNLQRIPHGRNELREGSGRKPVVFLQHGLLMDSTNWVLNSPHDSLGYILADKGFDVWLGNIRGNEYSAAHVKWNKDSSKFWDWTWQQM 149          
BLAST of Lipase vs. Ensembl Nematostella
Match: EDO41646 (Lipase [Source:UniProtKB/TrEMBL;Acc:A7S3Q1])

HSP 1 Score: 137.117 bits (344), Expect = 7.503e-40
Identity = 63/118 (53.39%), Postives = 84/118 (71.19%), Query Frame = 3
Query:  105 EEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTD--SRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDE 452
            + E  MNVS++I+ +GYP+E + V T+DGYI+S+QRIP+G      D  ++PV+ +QHGLL SS  +V+N P +SL FILADN FDVWL N RGNIY   H+  S +   FWDF+WDE
Sbjct:    5 DPEINMNVSQMIQYHGYPVENYDVITKDGYIISIQRIPFGQNGKCKDVPNKPVIFVQHGLLCSSTNWVANLPNESLAFILADNCFDVWLGNVRGNIYGMRHVNVSIHSDAFWDFSWDE 122          
BLAST of Lipase vs. Ensembl Nematostella
Match: EDO35549 (Lipase [Source:UniProtKB/TrEMBL;Acc:A7SL62])

HSP 1 Score: 132.88 bits (333), Expect = 7.682e-38
Identity = 64/117 (54.70%), Postives = 80/117 (68.38%), Query Frame = 3
Query:  111 EAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGL--KNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            E  MNV+++I+  GYP+E + VTTEDGYILS+QRIPYG   K      +PVV LQHGLL S+  +V+N   +S GFILAD  FDVWL N RGN Y   H+K   +   FWDF++DEM
Sbjct:   46 EVHMNVTQLIQYNGYPVEDYDVTTEDGYILSVQRIPYGREGKCKGVKDKPVVFLQHGLLCSATNWVTNLYNESFGFILADQCFDVWLGNVRGNTYGKRHVKLPVDSDAFWDFSFDEM 162          
BLAST of Lipase vs. Ensembl Nematostella
Match: EDO29518 (Lipase [Source:UniProtKB/TrEMBL;Acc:A7T3E6])

HSP 1 Score: 129.028 bits (323), Expect = 1.324e-36
Identity = 65/129 (50.39%), Postives = 84/129 (65.12%), Query Frame = 3
Query:   75 NGLLHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGL--KNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            N LL  +  ++ E  M  +++I+  GYP+E + VTTEDGYILS+QRIPYG   K      +PVV LQHGLL S+  +V+N   +S GFILAD  FDVWL N RGN Y   H+K   +   FWDF++DEM
Sbjct:    8 NCLL--QKCLKPETNMIFTQLIQYNGYPVEDYDVTTEDGYILSVQRIPYGREGKCKGVKDKPVVFLQHGLLCSATNWVTNLYNESFGFILADQCFDVWLGNVRGNTYGKRHVKLPVDSDAFWDFSFDEM 134          
BLAST of Lipase vs. Ensembl Medaka
Match: lipf (lysosomal acid lipase/cholesteryl ester hydrolase-like [Source:NCBI gene;Acc:101156001])

HSP 1 Score: 143.665 bits (361), Expect = 1.305e-41
Identity = 64/118 (54.24%), Postives = 86/118 (72.88%), Query Frame = 3
Query:  102 IEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            ++ E  MN+SEII+ +GYP E H V TEDGYILS+ RIP GLK T+   +P VLLQHGLL +   +V+N P  SLGF+LAD G+DVW+ NSRGN +S  H   + ++++FW F++DEM
Sbjct:   36 LDPEVNMNISEIIRRWGYPAEEHEVVTEDGYILSVNRIPSGLKRTA-GPKPAVLLQHGLLAAGSNWVTNPPSSSLGFVLADAGYDVWIGNSRGNTWSKRHRTLTPDQEDFWKFSYDEM 152          
BLAST of Lipase vs. Ensembl Medaka
Match: lipf (lysosomal acid lipase/cholesteryl ester hydrolase-like [Source:NCBI gene;Acc:101156001])

HSP 1 Score: 135.191 bits (339), Expect = 1.634e-38
Identity = 61/109 (55.96%), Postives = 80/109 (73.39%), Query Frame = 3
Query:  129 SEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            SEII+ +GYP E H V TEDGYILS+ RIP GLK T+   +P VLLQHGLL +   +V+N P  SLGF+LAD G+DVW+ NSRGN +S  H   + ++++FW F++DEM
Sbjct:   34 SEIIRRWGYPAEEHEVVTEDGYILSVNRIPSGLKRTA-GPKPAVLLQHGLLAAGSNWVTNPPSSSLGFVLADAGYDVWIGNSRGNTWSKRHRTLTPDQEDFWKFSYDEM 141          
BLAST of Lipase vs. Ensembl Medaka
Match: lipf (lysosomal acid lipase/cholesteryl ester hydrolase-like [Source:NCBI gene;Acc:101156001])

HSP 1 Score: 133.265 bits (334), Expect = 4.961e-38
Identity = 60/108 (55.56%), Postives = 79/108 (73.15%), Query Frame = 3
Query:  132 EIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            EII+ +GYP E H V TEDGYILS+ RIP GLK T+   +P VLLQHGLL +   +V+N P  SLGF+LAD G+DVW+ NSRGN +S  H   + ++++FW F++DEM
Sbjct:   10 EIIRRWGYPAEEHEVVTEDGYILSVNRIPSGLKRTA-GPKPAVLLQHGLLAAGSNWVTNPPSSSLGFVLADAGYDVWIGNSRGNTWSKRHRTLTPDQEDFWKFSYDEM 116          
BLAST of Lipase vs. Planmine SMEST
Match: SMESG000055087.1 (SMESG000055087.1)

HSP 1 Score: 299.286 bits (765), Expect = 1.239e-105
Identity = 145/145 (100.00%), Postives = 145/145 (100.00%), Query Frame = 3
Query:   21 MKRNLDFVGLSFFILFLGNGLLHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            MKRNLDFVGLSFFILFLGNGLLHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM
Sbjct:    1 MKRNLDFVGLSFFILFLGNGLLHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 145          
BLAST of Lipase vs. Planmine SMEST
Match: SMESG000074186.1 (SMESG000074186.1)

HSP 1 Score: 195.667 bits (496), Expect = 5.956e-62
Identity = 94/143 (65.73%), Postives = 114/143 (79.72%), Query Frame = 3
Query:   48 LSFFILF------LGNGLLHAEPSIEE-EAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            +S ++LF      L  G L   P+ ++ E KMNV+EII  Y YP E H VTTEDGYILSLQRIP+GLKN S  SRPVV LQHGL+DSSFT+V+NGP+KSLGF+LAD GFDVWLSN+RGN+YSNSHIKY+ +++ FWDFTWD+M
Sbjct:    1 MSIYLLFIEYFISLSVGQLQPPPASQDSEIKMNVTEIILYYNYPCENHLVTTEDGYILSLQRIPFGLKNNSLQSRPVVFLQHGLVDSSFTWVANGPDKSLGFVLADKGFDVWLSNTRGNVYSNSHIKYTTSDRNFWDFTWDDM 143          
BLAST of Lipase vs. Planmine SMEST
Match: SMESG000007797.1 (SMESG000007797.1)

HSP 1 Score: 185.652 bits (470), Expect = 4.415e-58
Identity = 86/131 (65.65%), Postives = 104/131 (79.39%), Query Frame = 3
Query:   63 LFLGNGLLHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            LF+ N L H   + + E  MNV+E+I  Y YP E H VTTEDGYILS+QRIP+G+K +S+  RPVV LQHGLLDSSFT+V+N P+KSL FILADNGFDVWL+NSRGN+YSN HIKY  +  +FWDF+WDEM
Sbjct:   12 LFITNALSHKYET-DPEIYMNVTEVINLYKYPCENHLVTTEDGYILSMQRIPFGIKMSSSSKRPVVFLQHGLLDSSFTWVNNAPDKSLAFILADNGFDVWLANSRGNVYSNKHIKYPTDSNKFWDFSWDEM 141          
BLAST of Lipase vs. Planmine SMEST
Match: SMESG000007797.1 (SMESG000007797.1)

HSP 1 Score: 185.652 bits (470), Expect = 4.705e-58
Identity = 86/131 (65.65%), Postives = 104/131 (79.39%), Query Frame = 3
Query:   63 LFLGNGLLHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
            LF+ N L H   + + E  MNV+E+I  Y YP E H VTTEDGYILS+QRIP+G+K +S+  RPVV LQHGLLDSSFT+V+N P+KSL FILADNGFDVWL+NSRGN+YSN HIKY  +  +FWDF+WDEM
Sbjct:   16 LFITNALSHKYET-DPEIYMNVTEVINLYKYPCENHLVTTEDGYILSMQRIPFGIKMSSSSKRPVVFLQHGLLDSSFTWVNNAPDKSLAFILADNGFDVWLANSRGNVYSNKHIKYPTDSNKFWDFSWDEM 145          
BLAST of Lipase vs. Planmine SMEST
Match: SMESG000074187.1 (SMESG000074187.1)

HSP 1 Score: 179.489 bits (454), Expect = 1.269e-55
Identity = 84/135 (62.22%), Postives = 99/135 (73.33%), Query Frame = 3
Query:   51 SFFILFLGNGLLHAEPSIEEEAKMNVSEIIKSYGYPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYVSNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDEM 455
               I+ +  GLL      + E  M+V+E+IK YGYPLE H VTTEDGYIL++QRIPYG  ++    +PVV LQHGLLDSSFT+V+NGPEKSL FILAD GFDVWL NSRGN YS  H K+S   + FWDFTWDEM
Sbjct:   11 CLLIVSINGGLLSPGIETDPEVTMDVNEVIKYYGYPLETHQVTTEDGYILTMQRIPYGRTSSPGIKKPVVFLQHGLLDSSFTWVNNGPEKSLAFILADRGFDVWLGNSRGNTYSRKHTKFSPFSKFFWDFTWDEM 145          
The following BLAST results are available for this feature:
BLAST of Lipase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
LIPM3.588e-4157.50lipase family member M [Source:HGNC Symbol;Acc:HGN... [more]
LIPA5.411e-4049.66lipase A, lysosomal acid type [Source:HGNC Symbol;... [more]
LIPA3.492e-3950.00lipase A, lysosomal acid type [Source:HGNC Symbol;... [more]
LIPF1.671e-3856.03lipase F, gastric type [Source:HGNC Symbol;Acc:HGN... [more]
LIPF1.941e-3856.03lipase F, gastric type [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of Lipase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lipl-21.712e-3945.27Lipase [Source:UniProtKB/TrEMBL;Acc:Q20449][more]
lipl-61.171e-3750.41LIPase Like [Source:UniProtKB/TrEMBL;Acc:E2S7J2][more]
lipl-41.373e-3650.00Lipase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUZ3][more]
lipl-55.830e-3547.20Lipase [Source:UniProtKB/TrEMBL;Acc:O61866][more]
lipl-55.830e-3547.20Lipase [Source:UniProtKB/TrEMBL;Acc:O61866][more]
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BLAST of Lipase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Lip46.472e-3750.40gene:FBgn0032264 transcript:FBtr0304119[more]
Lip47.395e-3750.40gene:FBgn0032264 transcript:FBtr0080093[more]
Lip47.782e-3745.81gene:FBgn0032264 transcript:FBtr0331672[more]
mag4.485e-3548.80gene:FBgn0036996 transcript:FBtr0078196[more]
CG183023.783e-3443.17gene:FBgn0032266 transcript:FBtr0080095[more]
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BLAST of Lipase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
lipf2.262e-4153.39lipase, gastric [Source:ZFIN;Acc:ZDB-GENE-040426-2... [more]
lipf2.262e-4153.39lipase, gastric [Source:ZFIN;Acc:ZDB-GENE-040426-2... [more]
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BLAST of Lipase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lipa2.621e-3853.78lipase A, lysosomal acid, cholesterol esterase [So... [more]
lipa6.144e-3551.72lipase A, lysosomal acid, cholesterol esterase [So... [more]
lipa8.188e-3551.75lipase A, lysosomal acid, cholesterol esterase [So... [more]
lipa1.144e-3452.68lipase A, lysosomal acid, cholesterol esterase [So... [more]
lipa2.339e-3453.70lipase A, lysosomal acid, cholesterol esterase [So... [more]
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BLAST of Lipase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Lipm9.739e-4058.33lipase, family member M [Source:MGI Symbol;Acc:MGI... [more]
Lipf6.005e-3855.17lipase, gastric [Source:MGI Symbol;Acc:MGI:1914967... [more]
Lipa2.493e-3755.83lysosomal acid lipase A [Source:MGI Symbol;Acc:MGI... [more]
Lipa2.493e-3755.83lysosomal acid lipase A [Source:MGI Symbol;Acc:MGI... [more]
Lipk4.334e-3752.99lipase, family member K [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of Lipase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5VYY2|LIPM_HUMAN1.723e-4057.50Lipase member M OS=Homo sapiens OX=9606 GN=LIPM PE... [more]
sp|Q29458|LIPG_BOVIN1.284e-3956.90Gastric triacylglycerol lipase OS=Bos taurus OX=99... [more]
sp|Q8K2A6|LIPM_MOUSE6.812e-3958.33Lipase member M OS=Mus musculus OX=10090 GN=Lipm P... [more]
sp|P07098|LIPG_HUMAN8.024e-3856.03Gastric triacylglycerol lipase OS=Homo sapiens OX=... [more]
sp|Q4R4S5|LICH_MACFA2.152e-3750.68Lysosomal acid lipase/cholesteryl ester hydrolase ... [more]
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BLAST of Lipase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A212CNN26.458e-4153.28Uncharacterized protein (Fragment) OS=Cervus elaph... [more]
A0A5N5T4Y37.126e-4154.55Lipase 1 OS=Armadillidium nasatum OX=96803 GN=Lip1... [more]
A0A2J7QG212.028e-4051.54Lipase 3 OS=Cryptotermes secundus OX=105785 GN=Lip... [more]
A0A016WCI62.639e-4051.09Abhydro_lipase domain-containing protein OS=Ancylo... [more]
A0A5N5T4S52.659e-4056.14Lipase 3 (Fragment) OS=Armadillidium nasatum OX=96... [more]
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BLAST of Lipase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
lipf4.313e-4355.83lysosomal acid lipase/cholesteryl ester hydrolase-... [more]
lipf9.356e-4351.15lysosomal acid lipase/cholesteryl ester hydrolase-... [more]
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BLAST of Lipase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
lipf1.801e-3643.13lipase, gastric [Source:ZFIN;Acc:ZDB-GENE-040426-2... [more]
lipf1.586e-3349.17lipase, gastric [Source:ZFIN;Acc:ZDB-GENE-040426-2... [more]
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BLAST of Lipase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
TGL14.191e-2141.32Steryl ester hydrolase; one of three gene products... [more]
YEH15.245e-1238.75Steryl ester hydrolase; one of three gene products... [more]
YEH26.985e-1235.51Steryl ester hydrolase; catalyzes steryl ester hyd... [more]
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BLAST of Lipase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO383985.122e-4047.95Lipase [Source:UniProtKB/TrEMBL;Acc:A7SCY7][more]
EDO407446.841e-4052.85Lipase [Source:UniProtKB/TrEMBL;Acc:A7S6G4][more]
EDO416467.503e-4053.39Lipase [Source:UniProtKB/TrEMBL;Acc:A7S3Q1][more]
EDO355497.682e-3854.70Lipase [Source:UniProtKB/TrEMBL;Acc:A7SL62][more]
EDO295181.324e-3650.39Lipase [Source:UniProtKB/TrEMBL;Acc:A7T3E6][more]
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BLAST of Lipase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
lipf1.305e-4154.24lysosomal acid lipase/cholesteryl ester hydrolase-... [more]
lipf1.634e-3855.96lysosomal acid lipase/cholesteryl ester hydrolase-... [more]
lipf4.961e-3855.56lysosomal acid lipase/cholesteryl ester hydrolase-... [more]
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BLAST of Lipase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000055087.11.239e-105100.00SMESG000055087.1[more]
SMESG000074186.15.956e-6265.73SMESG000074186.1[more]
SMESG000007797.14.415e-5865.65SMESG000007797.1[more]
SMESG000007797.14.705e-5865.65SMESG000007797.1[more]
SMESG000074187.11.269e-5562.22SMESG000074187.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002769 ID=SMED30002769|Name=Lipase|organism=Schmidtea mediterranea sexual|type=transcript|length=455bp
TGGAGATATTATTCAACTTCATGAAACGAAATTTAGATTTTGTTGGTTTG
AGTTTCTTTATCCTGTTTCTAGGCAACGGTCTCCTTCATGCTGAACCTTC
GATTGAAGAAGAGGCGAAGATGAATGTGAGTGAAATAATTAAATCTTATG
GCTATCCTCTCGAAATGCATTCGGTAACCACTGAAGACGGTTATATCCTT
TCTTTACAAAGAATTCCATATGGACTGAAAAACACTTCAACCGACTCACG
TCCAGTGGTACTTTTGCAACATGGACTTCTTGATTCTTCCTTTACTTATG
TTAGTAATGGACCTGAGAAGAGCTTGGGTTTCATTTTGGCTGACAATGGT
TTCGATGTATGGCTTTCTAACAGCAGAGGAAACATCTATTCCAACAGTCA
CATAAAATACTCAAAAAATGAACAAGAATTTTGGGATTTCACTTGGGATG
AAATG
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protein sequence of SMED30002769-orf-1

>SMED30002769-orf-1 ID=SMED30002769-orf-1|Name=SMED30002769-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=151bp
EILFNFMKRNLDFVGLSFFILFLGNGLLHAEPSIEEEAKMNVSEIIKSYG
YPLEMHSVTTEDGYILSLQRIPYGLKNTSTDSRPVVLLQHGLLDSSFTYV
SNGPEKSLGFILADNGFDVWLSNSRGNIYSNSHIKYSKNEQEFWDFTWDE
M
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004806triglyceride lipase activity
GO:0004465lipoprotein lipase activity
GO:0016787hydrolase activity
GO:0016788hydrolase activity, acting on ester bonds
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000419prepharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR006693AB_hydrolase_lipase
IPR029058AB_hydrolase
Vocabulary: biological process
TermDefinition
GO:0006629lipid metabolic process
GO:0016042lipid catabolic process
GO:0044241lipid digestion
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR029058Alpha/Beta hydrolase foldGENE3DG3DSA:3.40.50.1820coord: 29..151
e-value: 6.0E-53
score: 182.0
IPR029058Alpha/Beta hydrolase foldSUPERFAMILYSSF53474alpha/beta-Hydrolasescoord: 34..151
IPR006693Partial AB-hydrolase lipase domainPFAMPF04083Abhydro_lipasecoord: 42..103
e-value: 4.7E-24
score: 83.7
NoneNo IPR availablePANTHERPTHR11005:SF100LIPASEcoord: 36..151
NoneNo IPR availablePANTHERPTHR11005LYSOSOMAL ACID LIPASE-RELATEDcoord: 36..151
NoneNo IPR availableTMHMMTMhelixcoord: 13..30