Dystonin
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002742 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 72Note: Hover over icons to view figure legend
Homology
BLAST of Dystonin vs. Ensembl Human
Match: DST (dystonin [Source:HGNC Symbol;Acc:HGNC:1090]) HSP 1 Score: 859.751 bits (2220), Expect = 0.000e+0 Identity = 652/2260 (28.85%), Postives = 1169/2260 (51.73%), Query Frame = 3 Query: 12939 IGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND----------DSSIDESIKKLK------IIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETL----KNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNS-----VEKLVCQARNDLDKLKSVDAFENSL---------EKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKL-QIGIENCSPSRKNANDKDDSVE-ISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWND-LKLIEDKFHEMTIHLTNSTIEDL-----NTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSK-KIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTP------PLIPIFDRSKRMETNQGISKI-----QEPLFV-NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGD--CECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF--KFKPATLPIPTKKPTTAKIPSPRVSQPLSS--PRIHQPVSSP------RIPQPVTSPRISQNIPSSRVSQSLASPRT-----PKVVASPGLQRKSRIPTRQTSQQGSQAS 19454 + F +++++PL+ + +++ +G + + +E ++D V + L + V+ + L+ +F +LE+L ++ + + ++ PS E+ K+Q+ +LL L R+S+++ + + G + + K ++ +L L++++E LLN AE +N + + +++ F + EP WL T EK L N + T A ++E++I ++K L++D SI +S+K L ++ +K+D FS+ I+ + +KSH L N D+V L + E K KL++ D Y T +W++ E++ +E + +N+DQ G +L + ++ ++ I K+ + + +I+ + E ++ +A R + +L L D + ++ ++L+ E S ++L +A+N+ L S++ ++L E +E + E+ +R++ V + +T+K +I + +++ ++ D + ++ E+K+ + D + + ++L+ K +L K+ I+ + K++ + +S+K +D+V K ++ + + QL+ A L +F +Y L WL ET+ + Q L+ + L + ++E + L + KP +D + K+G L ++ + +G +I A Y+ IKE +K RA L++ I +T+ ++K+DQ LE I +R+ S EK+ E++ + D++KLQ + L Q G E + R DKD S + + D + + + EN + + E + K+++++ LA +FW D + LI +TI T I DL + V +++ E +R EID ++++ + G +LI P++ P V+++ +EL ++++ + + +I ++ + ++ + +W +L + P+ T+ V QI++ K+ K++ + ++E +N Q L K + + K+ V L + W L + + RQH+L+ LL+LG+F A+DE + W+ TE L+ K GD ++E+ LA+H +++ D+ Q++V + + ++I+ SS G EA+ +LE L + W+ + E + +L+ AL++A F+G+ +++ + + + L K GGLP+TAKEQL M++ F + +++ ++ + +S I+ D+ L +KW++V+ RK++LE+A+ FH + FINWLT E+ LN S I+ T+L Q++ H+ ++ SHRE+++ LDK THLKY SQK D+VLI+NL+ S+ RWEKVV R ER R+LD K AK+F + L++ + + + L+ + I P KI+ Q+ +HKEF +LG + YD+T R G L++K + D K+D+++ L+ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H +K+L R ++ + A L+ S +DSS+++ Q+ EL + W V L+ K+ RLE A QA EF + ++L E+ +++E LR + P++E + + +I H F K L ++N G +L +P++ +IKH+I II++++ ++L+W++Q L L L ++ LL+ LL WL AE TL + + + E K EH+ F+ +MT KQ D D++ K++ IP+ D+ + S + Q + NP++N L SKW+QVW + L RR++L D ++ L+E+ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C+ +++ Q GD KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCRV H G + S+++ + AKGRTN ELREK G MA F + + + P + S + +Q S P P +P R+P ++ S ++ + A RT K + PG + S+ +R +S++GS AS Sbjct: 430 VQVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLEHDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGT-QASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKLD--FSQVWYIEIQ-------------EKSHSRSELLQQALCNAKIFGEDEVELMN---WLNEVHDKLSKLSVQD-YSTEGLWKQQ----SELRVLQEDILLRKQNVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTWL----------DKVEVELLSYETQVLKGEEASQAQMRPKELKKEAKNNKALLDSLNEVSSALLELVPWRAREGLEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDIRLEQDQTSAQLQVQKTFTMEIL----RHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLEL-SPGEGFSIQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIA--RSGGTDKDISAKAVQDKLDQMVFIWEN--------------IHTLVEEREAKLLDVMELAEKFWCDHMSLI------VTIKDTQDFIRDLEDPGIDPSVVKQQQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDK-PIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIE---SSAGEEASNLQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAED-QPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGSRDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDE--DALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKHWITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEVIPQEIEEVKALIAEHQTFMEEMTRKQPDVDKVTKTYKRRAADPSSLQSHIPVLDKGRAGRKRFPASSLYPSGSQTQIETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPITDADKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGSKMLRSESNSSITTTQPTIAKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSVSSQAAQAASPQVPATTTPKGTPIQGSKLRLPGYLSGKGFHSGEDSGLITTAAARVRTQFADSKKTPSRPGSRAGSKAGSRASSRRGSDAS 2619
BLAST of Dystonin vs. Ensembl Human
Match: DST (dystonin [Source:HGNC Symbol;Acc:HGNC:1090]) HSP 1 Score: 854.358 bits (2206), Expect = 0.000e+0 Identity = 683/2477 (27.57%), Postives = 1237/2477 (49.94%), Query Frame = 3 Query: 12426 EMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVEN------LAEQKIETAEKSMHKID---NLAAINE---KIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIG-------AFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND----------DSSIDESIKKLK------IIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETL----KNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTA--LVRENDSLTGQ-VGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSL---------EKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKL-QIGIENCSPSRKNANDKDDSVE-ISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWND-LKLIEDKFHEMTIHLTNSTIEDL-----NTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSK-KIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTP------PLIPIFDRSKRMETNQGISKI-----QEPLFV-NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKF---------------KPATLPIPTKKPTTAKIPS---PRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQ-NIPSSRVSQSLASP-RTPKVVASPGLQR--------------------KSRIPTRQTSQQGSQASTRHQSR 19472 ++E I + LS + +K +L +K ++ Q +RE F + +LDS+ D L+++ I+ L L++ + + + + T E S + +L A+++ K+++ R+ + K + EF SK +F + +A E + ++ I F +++++PL+ + +++ +G + + +E ++D V + L + V+ + L+ +F +LE+L ++ + + ++ PS E+ K+Q+ +LL L R+S+++ + + G + + K ++ +L L++++E LLN AE +N + + +++ F + EP WL T EK L N + T A ++E++I ++K L++D SI +S+K L ++ +K+D FS+ I+ + +KSH L N D+V L + E K KL++ D Y T +W++ E++ +E + +N+DQ G +L + ++ ++ I K+ + + +I+ + E ++ +A R + +L L + L E L G+ + M E L +A+N+ L S++ ++L E +E + E+ +R++ V + +T+K +I + +++ ++ D + ++ E+K+ + D + + ++L+ K +L K+ I+ + K++ + +S+K +D+V K ++ + + QL+ A L +F +Y L WL ET+ + Q L+ + L + ++E + L + KP +D + K+G L ++ + +G +I A Y+ IKE +K RA L++ I +T+ ++K+DQ LE I +R+ S EK+ E++ + D++KLQ + L Q G E + R DKD S + + D + + + EN + + E + K+++++ LA +FW D + LI +TI T I DL + V +++ E +R EID ++++ + G +LI P++ P V+++ +EL ++++ + + +I ++ + ++ + +W +L + P+ T+ V QI++ K+ K++ + ++E +N Q L K + + K+ V L + W L + + RQH+L+ LL+LG+F A+DE + W+ TE L+ K GD ++E+ LA+H +++ D+ Q++V + + ++I+ SS G EA+ +LE L + W+ + E + +L+ AL++A F+G+ +++ + + + L K GGLP+TAKEQL M++ F + +++ ++ + +S I+ D+ L +KW++V+ RK++LE+A+ FH + FINWLT E+ LN S I+ T+L Q++ H+ ++ SHRE+++ LDK THLKY SQK D+VLI+NL+ S+ RWEKVV R ER R+LD K AK+F + L++ + + + L+ + I P KI+ Q+ +HKEF +LG + YD+T R G L++K + D K+D+++ L+ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H +K+L R ++ + A L+ S +DSS+++ Q+ EL + W V L+ K+ RLE A QA EF + ++L E+ +++E LR + P++E + + +I H F K L ++N G +L +P++ +IKH+I II++++ ++L+W++Q L L L ++ LL+ LL WL AE TL + + + E K EH+ F+ +MT KQ D D++ K++ IP+ D+ + S + Q + NP++N L SKW+QVW + L RR++L D ++ L+E+ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C+ +++ Q GD KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR AKGRTN ELREK G MA F+ + ++ + + ++P+ P++ PL+ +++ ++ P + S +PS+ + S R P ++ G + P+R S+ GS+A +R SR Sbjct: 2732 QVETIAQEHSTLSQQVDEKCSFLETK----------LQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKETIKAFLKKLEALMASNDNANKTCKMMLATEETSPDLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEESQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLEHDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGT-QASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKLD--FSQVWYIEIQ-------------EKSHSRSELLQQALCNAKIFGEDEVELMN---WLNEVHDKLSKLSVQD-YSTEGLWKQQ----SELRVLQEDILLRKQNVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTWLDKVEVELLSYETQVLKGEEASQAQMRPKE--------LKKEAKNNKALLDSLNEVSSALLELVPWRAREGLEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDIRLEQDQTSAQLQVQKTFTMEIL----RHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLEL-SPGEGFSIQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIA--RSGGTDKDISAKAVQDKLDQMVFIWEN--------------IHTLVEEREAKLLDVMELAEKFWCDHMSLI------VTIKDTQDFIRDLEDPGIDPSVVKQQQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDK-PIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIE---SSAGEEASNLQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAED-QPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGSRDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDE--DALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKHWITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEVIPQEIEEVKALIAEHQTFMEEMTRKQPDVDKVTKTYKRRAADPSSLQSHIPVLDKGRAGRKRFPASSLYPSGSQTQIETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPITDADKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------AKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSVSSQAAQAASPQVPATTTPKILHPLTRNYGKPWLTNSKMSTPCKAAECSDFPVPSAEGTPIQGSKLRLPGYLSGKGFHSGEDSGLITTAAARVRTQFADSKKTPSRPGSRAGSKAGSRASSR 5108 HSP 2 Score: 102.064 bits (253), Expect = 5.669e-20 Identity = 102/525 (19.43%), Postives = 227/525 (43.24%), Query Frame = 3 Query: 1725 PTLSSGVISNRQYTPIHSMELGDNVLYSSL---------------NKWKNWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAV 3209 P SSGV N T + M++ +L SSL NW+DE + + +DL + ++ E+F ++ E K + E +M + + + + + L++++ +L + + F+ ++ + W+ KE++++ + W + + ++ K++ L+ EL+ +E +I + L + NH A I+ A ++++W WIL L C++ H++ Y +FF +A EA + + L + + ++ + + E L +E + E + YK T+ ++ ++++ L R + + + +KAIC ++ + + E + L NNS W+V + P++CF + + +A A ++ + + LW + + ++ V L++ +D ++ + P Q+++ L + D + + + ++I + +N C + EL S+ Q +V N S V+ + Sbjct: 239 PNFSSGVEPNSLQT-LKLMQIRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAK--ISEIQMT------APLKLTYAEKLHRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSE-RNTNIARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEATDYLRNLKDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQYKSTIANLMGKAKTIIQLKPRNSDCPLKTSIPIKAICDYRQ---IEITIYKDDECV-LANNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDLANRIEQQYQNVLTLWHESHINMKSVVSWHYLINEIDRIRASNVASIKTMLPGEHQQVLSNLQSRFEDFLEDSQESQVFSGSDITQLEKEVNVCKQYYQELLKSAEREEQEESVYNLYISEVRNI 749
BLAST of Dystonin vs. Ensembl Human
Match: DST (dystonin [Source:HGNC Symbol;Acc:HGNC:1090]) HSP 1 Score: 853.203 bits (2203), Expect = 0.000e+0 Identity = 681/2479 (27.47%), Postives = 1240/2479 (50.02%), Query Frame = 3 Query: 12426 EMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVEN------LAEQKIETAEKSMHKID---NLAAINE---KIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIG-------AFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND----------DSSIDESIKKLK------IIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETL----KNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNS-----VEKLVCQARNDLDKLKSVDAFENSL---------EKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKL-QIGIENCSPSRKNANDKDDSVE-ISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWND-LKLIEDKFHEMTIHLTNSTIEDL-----NTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSK-KIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTP------PLIPIFDRSKRMETNQGISKI-----QEPLFV-NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKF---------------KPATLPIPTKKPTTAKIPS---PRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQ-NIPSSRVSQSLASP-RTPKVVASPGLQR--------------------KSRIPTRQTSQQGSQASTRHQSR 19472 ++E I + LS + +K +L +K + + Q +RE F + +LDS+ D L+++ I+ L L++ + + + + T E S + +L A+++ K+++ R+ + K + EF SK +F + +A E + ++ I F +++++PL+ + +++ +G + + +E ++D V + L + V+ + L+ +F +LE+L ++ + + ++ PS E+ K+Q+ +LL L R+S+++ + + G + + K ++ +L L++++E LLN AE +N + + +++ F + EP WL T EK L N + T A ++E++I ++K L++D SI +S+K L ++ +K+D FS+ I+ + +KSH L N D+V L + E K KL++ D Y T +W++ E++ +E + +N+DQ G +L + ++ ++ I K+ + + +I+ + E ++ +A R + +L L D + ++ ++L+ E S ++L +A+N+ L S++ ++L E +E + E+ +R++ V + +T+K +I + +++ ++ D + ++ E+K+ + D + + ++L+ K +L K+ I+ + K++ + +S+K +D+V K ++ + + QL+ A L +F +Y L WL ET+ + Q L+ + L + ++E + L + KP +D + K+G L ++ + +G +I A Y+ IKE +K RA L++ I +T+ ++K+DQ LE I +R+ S EK+ E++ + D++KLQ + L Q G E + R DKD S + + D + + + EN + + E + K+++++ LA +FW D + LI +TI T I DL + V +++ E +R EID ++++ + G +LI P++ P V+++ +EL ++++ + + +I ++ + ++ + +W +L + P+ T+ V QI++ K+ K++ + ++E +N Q L K + + K+ V L + W L + + RQH+L+ LL+LG+F A+DE + W+ TE L+ K GD ++E+ LA+H +++ D+ Q++V + + ++I+ SS G EA+ +LE L + W+ + E + +L+ AL++A F+G+ +++ + + + L K GGLP+TAKEQL M++ F + +++ ++ + +S I+ D+ L +KW++V+ RK++LE+A+ FH + FINWLT E+ LN S I+ T+L Q++ H+ ++ SHRE+++ LDK THLKY SQK D+VLI+NL+ S+ RWEKVV R ER R+LD K AK+F + L++ + + + L+ + I P KI+ Q+ +HKEF +LG + YD+T R G L++K + D K+D+++ L+ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H +K+L R ++ + A L+ S +DSS+++ Q+ EL + W V L+ K+ RLE A QA EF + ++L E+ +++E LR + P++E + + +I H F K L ++N G +L +P++ +IKH+I II++++ ++L+W++Q L L L ++ LL+ LL WL AE TL + + + E K EH+ F+ +MT KQ D D++ K++ IP+ D+ + S + Q + NP++N L SKW+QVW + L RR++L D ++ L+E+ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C+ +++ Q GD KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR AKGRTN ELREK G MA F+ + ++ + + ++P+ P++ PL+ +++ ++ P + S +PS+ + S R P ++ G + P+R S+ GS+A +R SR Sbjct: 3098 QVETIAQEHSTLSQQVDEKCSFLETKLQGIGHF----------QNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKETIKAFLKKLEALMASNDNANKTCKMMLATEETSPDLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEESQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLEHDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGT-QASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKLD--FSQVWYIEIQ-------------EKSHSRSELLQQALCNAKIFGEDEVELMN---WLNEVHDKLSKLSVQD-YSTEGLWKQQ----SELRVLQEDILLRKQNVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTWL----------DKVEVELLSYETQVLKGEEASQAQMRPKELKKEAKNNKALLDSLNEVSSALLELVPWRAREGLEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDIRLEQDQTSAQLQVQKTFTMEIL----RHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLEL-SPGEGFSIQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIA--RSGGTDKDISAKAVQDKLDQMVFIWEN--------------IHTLVEEREAKLLDVMELAEKFWCDHMSLI------VTIKDTQDFIRDLEDPGIDPSVVKQQQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDK-PIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIE---SSAGEEASNLQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAED-QPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGSRDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDE--DALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKHWITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEVIPQEIEEVKALIAEHQTFMEEMTRKQPDVDKVTKTYKRRAADPSSLQSHIPVLDKGRAGRKRFPASSLYPSGSQTQIETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPITDADKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------AKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSVSSQAAQAASPQVPATTTPKILHPLTRNYGKPWLTNSKMSTPCKAAECSDFPVPSAEGTPIQGSKLRLPGYLSGKGFHSGEDSGLITTAAARVRTQFADSKKTPSRPGSRAGSKAGSRASSR 5474 HSP 2 Score: 256.144 bits (653), Expect = 1.372e-66 Identity = 126/239 (52.72%), Postives = 171/239 (71.55%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPK 1085 LDP +R VLR+ADERD +QK+TF WIN HLMK+ K V D++ DLRDG L++LLEVLS L + RFH L+N+ LD+L+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +S+D+S K+ LL W+++A E Y I ENF+T W+DGK F A+IHK RPDLID+ +++ S NLE AF A+K +GV ++++PEDV DEKS++TYV+SL++ PK Sbjct: 59 LDPAERAVLRIADERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 296 HSP 3 Score: 102.834 bits (255), Expect = 2.922e-20 Identity = 102/525 (19.43%), Postives = 227/525 (43.24%), Query Frame = 3 Query: 1725 PTLSSGVISNRQYTPIHSMELGDNVLYSSL---------------NKWKNWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAV 3209 P SSGV N T + M++ +L SSL NW+DE + + +DL + ++ E+F ++ E K + E +M + + + + + L++++ +L + + F+ ++ + W+ KE++++ + W + + ++ K++ L+ EL+ +E +I + L + NH A I+ A ++++W WIL L C++ H++ Y +FF +A EA + + L + + ++ + + E L +E + E + YK T+ ++ ++++ L R + + + +KAIC ++ + + E + L NNS W+V + P++CF + + +A A ++ + + LW + + ++ V L++ +D ++ + P Q+++ L + D + + + ++I + +N C + EL S+ Q +V N S V+ + Sbjct: 605 PNFSSGVEPNSLQT-LKLMQIRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAK--ISEIQMTAP------LKLTYAEKLHRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSE-RNTNIARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEATDYLRNLKDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQYKSTIANLMGKAKTIIQLKPRNSDCPLKTSIPIKAICDYRQ---IEITIYKDDECV-LANNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDLANRIEQQYQNVLTLWHESHINMKSVVSWHYLINEIDRIRASNVASIKTMLPGEHQQVLSNLQSRFEDFLEDSQESQVFSGSDITQLEKEVNVCKQYYQELLKSAEREEQEESVYNLYISEVRNI 1115
BLAST of Dystonin vs. Ensembl Human
Match: DST (dystonin [Source:HGNC Symbol;Acc:HGNC:1090]) HSP 1 Score: 852.432 bits (2201), Expect = 0.000e+0 Identity = 681/2479 (27.47%), Postives = 1240/2479 (50.02%), Query Frame = 3 Query: 12426 EMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVEN------LAEQKIETAEKSMHKID---NLAAINE---KIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIG-------AFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND----------DSSIDESIKKLK------IIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETL----KNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNS-----VEKLVCQARNDLDKLKSVDAFENSL---------EKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKL-QIGIENCSPSRKNANDKDDSVE-ISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWND-LKLIEDKFHEMTIHLTNSTIEDL-----NTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSK-KIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTP------PLIPIFDRSKRMETNQGISKI-----QEPLFV-NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKF---------------KPATLPIPTKKPTTAKIPS---PRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQ-NIPSSRVSQSLASP-RTPKVVASPGLQR--------------------KSRIPTRQTSQQGSQASTRHQSR 19472 ++E I + LS + +K +L +K + + Q +RE F + +LDS+ D L+++ I+ L L++ + + + + T E S + +L A+++ K+++ R+ + K + EF SK +F + +A E + ++ I F +++++PL+ + +++ +G + + +E ++D V + L + V+ + L+ +F +LE+L ++ + + ++ PS E+ K+Q+ +LL L R+S+++ + + G + + K ++ +L L++++E LLN AE +N + + +++ F + EP WL T EK L N + T A ++E++I ++K L++D SI +S+K L ++ +K+D FS+ I+ + +KSH L N D+V L + E K KL++ D Y T +W++ E++ +E + +N+DQ G +L + ++ ++ I K+ + + +I+ + E ++ +A R + +L L D + ++ ++L+ E S ++L +A+N+ L S++ ++L E +E + E+ +R++ V + +T+K +I + +++ ++ D + ++ E+K+ + D + + ++L+ K +L K+ I+ + K++ + +S+K +D+V K ++ + + QL+ A L +F +Y L WL ET+ + Q L+ + L + ++E + L + KP +D + K+G L ++ + +G +I A Y+ IKE +K RA L++ I +T+ ++K+DQ LE I +R+ S EK+ E++ + D++KLQ + L Q G E + R DKD S + + D + + + EN + + E + K+++++ LA +FW D + LI +TI T I DL + V +++ E +R EID ++++ + G +LI P++ P V+++ +EL ++++ + + +I ++ + ++ + +W +L + P+ T+ V QI++ K+ K++ + ++E +N Q L K + + K+ V L + W L + + RQH+L+ LL+LG+F A+DE + W+ TE L+ K GD ++E+ LA+H +++ D+ Q++V + + ++I+ SS G EA+ +LE L + W+ + E + +L+ AL++A F+G+ +++ + + + L K GGLP+TAKEQL M++ F + +++ ++ + +S I+ D+ L +KW++V+ RK++LE+A+ FH + FINWLT E+ LN S I+ T+L Q++ H+ ++ SHRE+++ LDK THLKY SQK D+VLI+NL+ S+ RWEKVV R ER R+LD K AK+F + L++ + + + L+ + I P KI+ Q+ +HKEF +LG + YD+T R G L++K + D K+D+++ L+ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H +K+L R ++ + A L+ S +DSS+++ Q+ EL + W V L+ K+ RLE A QA EF + ++L E+ +++E LR + P++E + + +I H F K L ++N G +L +P++ +IKH+I II++++ ++L+W++Q L L L ++ LL+ LL WL AE TL + + + E K EH+ F+ +MT KQ D D++ K++ IP+ D+ + S + Q + NP++N L SKW+QVW + L RR++L D ++ L+E+ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C+ +++ Q GD KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR AKGRTN ELREK G MA F+ + ++ + + ++P+ P++ PL+ +++ ++ P + S +PS+ + S R P ++ G + P+R S+ GS+A +R SR Sbjct: 3058 QVETIAQEHSTLSQQVDEKCSFLETKLQGIGHF----------QNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKETIKAFLKKLEALMASNDNANKTCKMMLATEETSPDLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEESQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLEHDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGT-QASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKLD--FSQVWYIEIQ-------------EKSHSRSELLQQALCNAKIFGEDEVELMN---WLNEVHDKLSKLSVQD-YSTEGLWKQQ----SELRVLQEDILLRKQNVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTWL----------DKVEVELLSYETQVLKGEEASQAQMRPKELKKEAKNNKALLDSLNEVSSALLELVPWRAREGLEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDIRLEQDQTSAQLQVQKTFTMEIL----RHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLEL-SPGEGFSIQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIA--RSGGTDKDISAKAVQDKLDQMVFIWEN--------------IHTLVEEREAKLLDVMELAEKFWCDHMSLI------VTIKDTQDFIRDLEDPGIDPSVVKQQQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDK-PIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIE---SSAGEEASNLQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAED-QPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGSRDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDE--DALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKHWITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEVIPQEIEEVKALIAEHQTFMEEMTRKQPDVDKVTKTYKRRAADPSSLQSHIPVLDKGRAGRKRFPASSLYPSGSQTQIETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPITDADKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------AKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSVSSQAAQAASPQVPATTTPKILHPLTRNYGKPWLTNSKMSTPCKAAECSDFPVPSAEGTPIQGSKLRLPGYLSGKGFHSGEDSGLITTAAARVRTQFADSKKTPSRPGSRAGSKAGSRASSR 5434 HSP 2 Score: 239.58 bits (610), Expect = 1.360e-61 Identity = 120/239 (50.21%), Postives = 166/239 (69.46%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPK 1085 L + ++ R DERD +QK+TF WIN HLMK+ K V D++ DLRDG L++LLEVLS L + RFH L+N+ LD+L+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +S+D+S K+ LL W+++A E Y I ENF+T W+DGK F A+IHK RPDLID+ +++ S NLE AF A+K +GV ++++PEDV DEKS++TYV+SL++ PK Sbjct: 19 LQAYEDVLERYKDERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 256 HSP 3 Score: 102.834 bits (255), Expect = 3.338e-20 Identity = 102/525 (19.43%), Postives = 227/525 (43.24%), Query Frame = 3 Query: 1725 PTLSSGVISNRQYTPIHSMELGDNVLYSSL---------------NKWKNWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAV 3209 P SSGV N T + M++ +L SSL NW+DE + + +DL + ++ E+F ++ E K + E +M + + + + + L++++ +L + + F+ ++ + W+ KE++++ + W + + ++ K++ L+ EL+ +E +I + L + NH A I+ A ++++W WIL L C++ H++ Y +FF +A EA + + L + + ++ + + E L +E + E + YK T+ ++ ++++ L R + + + +KAIC ++ + + E + L NNS W+V + P++CF + + +A A ++ + + LW + + ++ V L++ +D ++ + P Q+++ L + D + + + ++I + +N C + EL S+ Q +V N S V+ + Sbjct: 565 PNFSSGVEPNSLQT-LKLMQIRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAK--ISEIQMTAP------LKLTYAEKLHRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSE-RNTNIARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEATDYLRNLKDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQYKSTIANLMGKAKTIIQLKPRNSDCPLKTSIPIKAICDYRQ---IEITIYKDDECV-LANNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDLANRIEQQYQNVLTLWHESHINMKSVVSWHYLINEIDRIRASNVASIKTMLPGEHQQVLSNLQSRFEDFLEDSQESQVFSGSDITQLEKEVNVCKQYYQELLKSAEREEQEESVYNLYISEVRNI 1075
BLAST of Dystonin vs. Ensembl Human
Match: MACF1 (microtubule actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:13664]) HSP 1 Score: 821.231 bits (2120), Expect = 0.000e+0 Identity = 662/2433 (27.21%), Postives = 1203/2433 (49.45%), Query Frame = 3 Query: 12486 IYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINE---KIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPEL--------------AKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND----DSSIDESIK---KLKIIINKVD-GVFSENVSIDTKNKINKLFDRFSEYQ-KSHYXXXXXXXXXXXXXXXXXDQVNLF------EDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVREND----SLTGQ--VGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSL------EKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMS------DQINNDYSELEECKIDFTNLLSAWNE---QKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNE---KVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSP------SRKNANDKDDSV-EISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLG-YQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTF-PKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPI-QDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKT--PPLIPIFDRSKRMETNQGISKIQEPLFV--------NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF-----KFKPAT---------------LPIPTKKPTTAKIPSPRVSQ-PLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRT-PKVVAS-PGLQRKSRIPTRQTSQQGSQAS 19454 + + +K + + + R+ ++ +L +++D D DSL+ QI D+ + + ++ + ++E ++ E++ + + L A+N+ K+ E RQ L L V DF RK+ N+ +++N + F +++VDPL+ +L+++ +G + + +E +M+ + ++ L + V+ + L+ KF +LE L ++ + + ++ PS EY K+Q+ +LL L R++++D L G + + + + ++ +L+ L +++ LL+ A + + + + L+K F + EP +L EK LAN + T A +++++I +K L+ D + + +++K L + + + GV SE KI+ L R+SE Q + + L N D+V + ED L +KD K +++ + L L +E+ + + KN+DQ G+ L + ++ + I K++ + + +I+V++ K L E + +A +F LT +RE + + GQ GE+ + + ++K V + R LD + V L E ++ + + +++K V + + ++ +I + +++ E+ D + ++ ++K+ + DQ + ID + +E + I T + +K + L+ + + +Q E+ + + +L+ A L +F +Y L W+ ET + Q +D +QL + ++E++ L S + KP +D ++K G L ++ N +G+ + + A+ Y IKE ++ RA L++ + +T++ E K++ LEN+ R+ P + P ++D+ E + D + ++KLQ E R DKD + EI D + + E+ ++++ E + K +++L LA +FW D+ + TI T + DL + ++ + + E ++ E D +++ I G LI E P+V ++ +E+ +E + + ++++ ++ + ++ + +W +L + P+ T+ V Q+ + KE K ++ + ++E +N G L K + ++ + L + W L + + RQH+L+ LL+LG+F A++E + W+ TE L + GD +E+ LA+H +++ D+ QA+V + + E+++ SS G +A+ RLE + + WE + + + +L+ L++A F+ + ++ + + S+L K +GGLP+TA+EQL M++Y K + + + + G E + +L +KW V + E RKS+LE+A+ F + +FINWLTL E++LN P S I++T+L Q+E H+ ++ +HR++++ LD+ LK++SQK D+VLI+NL+ S+ RWEKVV RS ER R+LD K AK+F + + L+D + L+ + I P KI+ Q++KHKEF LG YD+T R G L++K + +DS+K+D + ++ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + L+ S +D+++++ QL EL + W+ V KL+ K+ RLE+A QA F + L E+ S++E LR P++ E + ++I H F K + + +N G IL +P+ +IKH+I II++++ ++L+W++Q L+ L L LL++LL W+ AE TL+ + + + K EH+ F+ +MT KQ D D + K+K P P ++S R + +S+ P NP+INQL ++W+QVW + L R+++L D ++ L+E++ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF TT++EM VADIFD++ G+IDY +F+AAL P+++ Y +P + + I DEV +Q+++C C+ +++ Q G+ KY+FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR A+GRTN ELREK P+G M PF + KP++ T P++ P+ P S ++ +P +P TS + SS S + R PK AS PG + SR +R +S++GS AS Sbjct: 2999 VMMENKLEGIGQFHCRVREMFSQLADLDDELDGMGAIGRDTDSLQSQIEDVRLFLNKIHVLKLDIEASEAECRHMLEEEGTLDLLGLKR--ELEALNKQCGKLTERGKARQEQLELTLGRV-------EDFYRKLKGLNDATTAAEEAEALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA-KIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGVLSE--------KIDSLQARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNWLAEVEDKLSSV--FVKDFKQDVLHRQHA-----DHLALNEEIVNRK---KNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKF-------QSTYEELTGWLREVEEELATSGGQSPTGEQ-IPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKLVSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEEQKTV----------LQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKPHIDKLLKIGPQLKEL-NPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLR---MPPLIPAEVDK----IRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWED--------------IKARAEEREIKFLDVLELAEKFWYDMAALL-----TTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGE-TEKPEVRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLE---SSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAED-QPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT--EALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALIAEHQTFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKS-RSGGRKSLSQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAY--RPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------ARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRP--TPTFHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDAS 5324 HSP 2 Score: 231.106 bits (588), Expect = 6.346e-59 Identity = 114/227 (50.22%), Postives = 157/227 (69.16%), Query Frame = 3 Query: 405 DERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPK 1085 DERD +QK+TF W+N HLMK+ K + D++ DLRDG L++LLEVLS KL + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI S +S D+S K+ LL W++K Y I NFS+ W DGK F ALIH+ RPDL+D++ + S ++NLE AF A++ LGV ++++ EDV DEKS++TYV+S+++ PK Sbjct: 23 DERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQIQSNRENLEQAFEVAER-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPK 248 HSP 3 Score: 106.301 bits (264), Expect = 2.512e-21 Identity = 161/832 (19.35%), Postives = 362/832 (43.51%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGLN---KIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKND----LKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLS------TMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVN------DLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKD---VPTNLDQLISAVTTSRQNQKDVSYE---DIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGL--QTTVKSQINVPNNVFESKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYEDIFKNYQNEIQNQIGGSNQDYFGYTKRSRIQNAHDWVSCE 4238 +W++E + + NDL + + + T+ E+ SV E ++ + +M +FH S + L+T++ +L S +S +F+ ++ + W+ KE++++ + W D S +S K+ F L ELE ++ L++ NH A ++ A ++S+ QW+ L C++ H++ Y QFF +A E ++ + L + + ++ L E L ++ D E + K +V ++ S+++ L R+ + + ++VKA+C ++ + + L +NS W+V + P++CFLI + A + A ++ + + LW +L + + L+S +DLV+ W E + P +I++ L + D + + + + + + C ARF L S + TV+ S +K ++ L+L++ K +Q S+ + ++ + + + +L+ ++ D L S L+ +L +++ + ++ + +++ KLK+ +V + + + ++ E+ L +Q E A ++ LEA T+ + ++KD V + LD+ I+ + ++ E D+++ +++ ++ R+ + Q++ R S + E + LG + +A +I +TT + ++ P +S+ + + + EI + + ++D+ K + + +++ YE Y+ +++Q Q G KR R+ ++ D ++ E Sbjct: 543 SWVEEMQMKLERAEWGNDLPSVELQLETQQHIHTSVEELGSSVKEARLY-----EGKMSQNFHTSYAETLGKLETQYCKLKETSSFRMRHLQSLHKFVSRATAELIWLNEKEEEELAYDWSDNNS-NISAKRNYFSELTMELEEKQDVFRSLQDTAELLSLENHPAKQTVEAYSAAVQSQLQWMKQLCLCVEQHVKENTAYFQFFSDARELESFLRNLQDSIKRKYSCDHNTSLSRLEDLLQDSMDEKEQLIQSKSSVASLVGRSKTIVQLKPRSPDHVLKNTISVKAVCDYRQ----IEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNKDAIEMASRVEQSYQKVMALW--HQLHVNTKSLISWNYLRKDLDLVQTWNLEKLRSSAPGECHQIMKNLQAHYEDFLQDSRDSVLFSVADRLRLEEEVEACKARFQHLMKSMENEDKEETVAKMYISELK--------NIRLRLEEYEQRVVKRIQ--SLASSRTDRDAWQDNALRIAEQEHTQEDLQQLRSDLDAVSMKCDSFLHQSPSSSSVPTLRSELNLLVEKMDHVYGLSTVYLNKLKTVDVIVRSIQDAELLVKGYEIKL-SQEEVVLAD-------LSALEAHWSTLRHWLSDVKDKNSVFSVLDEEIAKAKVVAEQMSRLTPERNLDLERYQEKGSQLQERWHRVIAQLEIRQSEL-ESIQEVLG---DYRACHGTLIKWIEETTAQQEMMKPGQAEDSRVLSEQLSQQTALFAEIERNQTKLDQCQKFSQQYSTIVKDYELQLMTYKAFVESQ-----QKSPG--KRRRMLSSSDAITQE 1333
BLAST of Dystonin vs. Ensembl Celegans
Match: vab-10 (VAB-10B protein [Source:UniProtKB/TrEMBL;Acc:G5EFM4]) HSP 1 Score: 446.047 bits (1146), Expect = 2.419e-124 Identity = 509/2233 (22.79%), Postives = 1005/2233 (45.01%), Query Frame = 3 Query: 12957 QKVDPLKKQLE---ELIDIGNKACSTVISGLGFKHMEQEMDS----VKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLIN-TKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSP-TVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVD--PYQTRDIWEESLNLVKE----VKSHEETLKNLDQVGEDLKQISSENDSAAI-NCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNME---ILENETN-----SVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQ--APGSDL-KSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQN-KINNLDPD----QLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNI--DRQQSLITKLEEMRM------KLDEWFKEVNNRLFILGPLPTETRPVLTQI-QKTKEL---KNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMI--RADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRF----MDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWL-RAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQ-YNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF------KFKPAT-LPIPTKK---------PTTAKIPSPRVSQPLSSPRIH---QPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTP----KVVASPGLQRKSRIPT 19421 +KV LK+ L+ E +D N C +I G + +E+DS V ++ ++ VSD E VD + ++ K + + L ++E ++ ++PS + +K+QL+ + +L+ ++ ++ S+D ++ + + +K L N+ ++ +Y++LLN A + + AV L++ ++ P WL +A+K L P TV+ + E+ I E + LQ++ ++ LK ++ ++ + + VS++ N I+ ++ ++ + + + L + + F ++KL +D P + D+ E++ N++ E + +E + N+ +VG+ L I E + A I K++ L + ++ SA +K++L +IP++E F + D V+ L + R+ ++ + E E +LE + + SV++L + N L L S D ++++ + K V + V ++A +I +++ ++L +E S ++I E + + S+L+ +I TN ++ N K + ++KK+ RQ G++ + + VD K+ E + + L+ A+ L ++ S ++ L WL + + + + + P ++H +E+ + ++ +P+++ L +++ Q + + + + Y ++E ++ R +++++ E+++ L+ DR+ ++ S P L+ L I+ L Q D L ++ A++ S D+ + K N LEKL K ++ + ++ + ++L A FW++L + ++ L + + D+++++ + E++ I +S GKQL + V PD E+A ++ VR IT + ++++ LI +EE +L +W +L + P+ E +T+I Q KEL K+++ + E + QL + P++ V +A +N W+RL L +R+H+L+ ++L +G+ + + W+ T +L +I +N ++ +AQ K++ D++ Q SV+ + R A + I+ +L E + L+ + WE++++ + F++E A KEA G+ ++ + ++E S L K +GGLP+TA+ QL F +D+ L + + E + + + K + KW+ VK L R+ +L+ A E + +W+ E+ L Q +SR+ I +Q+ H + ++ + M H++Y +K D + I+N + S+ HR EK+ R++ER++ L E ++D L I+ L + + + + K++ ++ + KE ++ +D TR+ G L ++A + K+I + KW + K +R + A+L G ++++M +L SW+ +E + D++ V+ L++E S + + +++ ++ + A ALM ++ I L WN V + A + ++EA+ A EF+ ++L ++ + E +L+ + +E E + M G + + L + G EIL P AE +++++ +++++W ++ ++R L + + E+ A + EL+ + + Q + E+ I D + + +++ P + +K+ N P L ++WK++W + + L + L+E++ ++ + +EDW+ RY+ W +H+K+RV D FRR D H G V R+ FIDGII SKF T+R+EM VAD FDK G I+ ++F+ ALR D KP + E I E++ Q C+C PY+I + + Y+FGDT R+VRILRS VMVR+GGGW +LDEFL KHDPCR AKGR N + + + P +++M F K P T P P K P + + + H +P PR P +++ R+S+ S S+ TP +S R++RIP+ Sbjct: 2814 EKVRQLKESLKPVGEKMDAFNTDCKLLIKTAGPESDTKELDSLLKKVGDAYSDVVGKVSDKEMSVDAAVQQQGKVEDAYRALLNWLEETEEMMENRKKPSADAKVAKAQLHDYEVLMKHVEDKKPSVDGFKAMIEKIVAEASSDEEKKALGNKNAQIEDRYKDLLNSAVDRQRKLLDAVDLAERLQEVTIPLDSWLQSADKRLQALAKVPITVE--KAEEMIGEQEALQDE---LEHKSDDLKDVL-EIAPMLASLVSVEDANSISGQVNQLEARARALDAGITNMRPLLESFLQQIQDFTLDAEDMTQF-VGETEVKLGELDELPIEPDDLVEQT-NILAEIAVSIADRDEMMANIFEVGKQLA-IQGEPEEALIAQKKLDDLKFRYADLMTSADEKIALLAKAIPLSEGF---HEGFDTVMQVLEDMDRDLQTIDEEDPETQAELIFLLEEDISQKMRPSVDELTALS-NQLQVLCSAD----KADELQTNTIAMNKLVNSVADRVARRAERIEMASKQSRAVLDDLQYLIEWFSAARERILEGAPPSLDLEVLKSQLKHQRI--TNEEASAN--KVQFRNVAGEAKKVARQLGMEGNEANEKISDTVDEGKELVEEVMALCADRTETLERALALMEQLTSQFDELNKWLDQMDAELQASPSVTTATPAAELREMHDHNEELARMVAAY---RPIIEGFKSDVGSLHEVLAEDQAPLLESVAGELVQGYEEVREAVRARGHAIDNMMGATIGFGERLETLVANLQGAADRLRENEGISADPSVLESRLAENRSIVESLRDKQNAYDAL----------KQTASELLASAPEGDAAAGDVENKLNRLEKLW------KEIEREAVDRGVLLEDVLDKAKHFWSELDSCQKAVDDLRNRLELVEPATGHPEQLADQQEIMAQVASEMERARPRIEALSIAGKQLADYV------PDDEKA--VIENQVANVRGGF-STITGLFAEKKRDLIAAMEEAMTFHGDLQELLKWLDMAEQKLLKMSPV--EHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQLAADAPPHLAATVRQPVADLNTRWSRLNAALAEREHKLENLMLQMGKLASTIAQLTAWMDKTRATLKDIAPPKNAVNLRDIEIAQCKLVVLSNDIHAHQDSVNAVNRAAQKYIQTS-GALDAETSDSLKSMNLKWEDIQKVLESLAFDMEVAKKEAENVGGEVEKWQRWLEETESALLSTKPTGGLPETAEFQLDEFKALKLDVEHNASPLEAHLHATEQHLKEEPQDADTWLSKT----HGAMKTKWNKVKELLVDREKKLQVAYEQAVALESALNDMEDWIIAAERKLTDQPSISRLPDVIEKQLAEHESWMEEVAGRKMAMTKHQASGVHMQYYCEKKDAIPIKNRLVSLKHRVEKISGRTAERAKQLAVTRDEVATWQDGLHDLEHFISDVLVKIAPEPNTTSSLEKLKAKLEEVKEAQRDVTAKQTLFDVTRKRGIGLAERATRSEYKQISMTNEKMSKKWAEMLKKLRDRLREAEQAVLEGGAFEESMNDLESWVDDELERYQKAEHEPVFADIDGVRALVDEESRRSAERKTKENGVKTVVKKADALMASGVDEKDSIAQAKERLVEKWNQVEEAARHRGNSIKEAEQAAEEFDAKTHALLDWLAVEEQKLKASGL---DEVEGVKQEMDEAKGRYQECL-----------KKGEEILSKCQPAAEPILRNWMRVVEARWKEVSEKVDEREFTLLEQEQKAKEQN--------EQIEKLAKFAAQKREELNRMIEQPPAQDLDTMEQNICDFA-------NLDSELREQQPEVDAACKSAKKGARN-------------PAAEMLSTEWKKLWLDAMGLQSSLDNQKALLEEMKRLEGWKWEDWKERYVEWNDHAKARVNDLFRRIDRLHTGNVPRQVFIDGIIGSKFPTSRLEMAKVADRFDK-GDGMINAKEFINALRFDASNRNAKPQTDTEKITHEIELQKKTCSCCTPYQIEKISENHYRFGDTHIKRMVRILRSTVMVRVGGGWESLDEFLHKHDPCR----------------------AKGRLNINMFPE-ARPIHALDSMRSFTKNRHGKQLPTTGTPGPIMKIREKTDRSVPMSGGLGGTAGYTVTTDSHRHTDARPSRIPRAPSDMSAGRLSRVGSVSNSKNSIVDSSTPSRPESRASSDAGDRQTRIPS 4924 HSP 2 Score: 352.443 bits (903), Expect = 4.521e-96 Identity = 332/1337 (24.83%), Postives = 617/1337 (46.15%), Query Frame = 3 Query: 405 DERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQ------------SSK------------SDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQ--QNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIE----------EKIYQFRN------QYADLYANLNSALEELNDDFDHNDFRIDFNQTRLENNYLTYLKQYESFCHLFDDISKVDRNNENQRKFHTIST-----LWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDGYP-ADQHYRIIININGK----IDKVKKKFEKLSPPTLSSGVISNRQYTPIHSMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLDGLNKIYEKFSTTFNEIKD---SVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICS-SKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANIDENE--INKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIK------------ILIAQLEAAQDTISSVVGNLKDVPTNLDQLISAVTTSRQNQKDVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFE---SKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYEDIFKNYQNEIQNQIGGSNQDYFGYTK 4196 DERD +QK+TF W+N HL K + ++ D+F DLRDG L+ LLE L+ +++ +N +RFH ++N+ LDFL+ +NIKLVNI ED+V+GN KLTLGL+W IIL FQ I Q S+K SD S + LLQW+R+ YP +N+ NFS+SW+DG AF A++H+ R ID IS +S + L AF A +E GV ++++ EDV + DEKS++TYV+SL+ P E ++ E+ Y++R Q D +L EL ++ FR D R E Q +++ + KV R+ E H +S +W++ + + + +L + S + L K++ I +I + + +P + ++ I +L E+ I V+ELK +P A+ Y+ + ++ + +D++ + L + + + + +M +S + + W+ + ++ + F DL+ L ++E+ +I+D +VDE + ++E + ++ + L++++ +L + D S + F+ + + W+ +E ++ W D + + L +K L+ E+E+RE N+ G L H A I+ L ++S+W W+L L+ CL+ HL + F EA++A+ I E + +L + + R L+EGE RE+ ++ E + Y + + + S+S L R I P + V A+C S EN G+ + L +NS W + + P++ F I + + L F LK LW K+ +R ++L+TM ++ W + F +++P R I++ LN DAN+L+ +L D N+ + L + N F L ++ S + P A + D ++ +L+ + +EL+ + P+ + LE + HK FE L+ + V ++ + + T +V +R+ LW+ LW+ + M+V ++K E + + E+ ++ + E+TL N + PA +D+++ + +++L A + S + + N+ L V+ +R N+ + D+ ++ E++ + R+E + +QI RL V + ++E + +W+ ++ T+ +++ P + + ++ L+ + N Q ++ I+ +NK F++ + ++ Y + I G + F TK Sbjct: 35 DERDNVQKKTFTKWVNKHLSKTDHKIDDLFVDLRDGYALIALLEALTGERIQKENGYTRFHRIQNVQYCLDFLKKKNIKLVNIRPEDIVEGNGKLTLGLIWTIILNFQVSVIRQRLLLESSQHEQMSAKHTTTNSQVSLHGSDATSARDALLQWARRVTAGYPRVNVNNFSSSWRDGLAFNAILHRYRSSAIDWNKISSDSVSNTERLNNAFAAADREFGVERLLDAEDVDTNNPDEKSIITYVSSLYNALPHEPEMSRLQKVQEEYIEEAYEWREWVVRAIQLVD-DRHLQGTASELI--YELQRFREDDLPPREE--------QKRRLTLVYEHLEKVMRSTELFAIPHELSAPELQRVWNELQNSIDRRFDVLERHRIQEGNSNDLLSRLARGIGITNEKLDLILKRIEDVEARVDTSPPAAVERTVSEIVDDLNALESPIARFFEDVEELKSMQHPEANDFYKQVYGLHQRRTTYLDRLTNQI--LVRLGVRTDSLHKENQQRLENMR---KTSFSRVEECIEWVRVRMEKLTTMEFLEDLETLEHVFEQHKFDNRDIQDFRQNVDEC-IARQAEVSAEDTYEYCELLRVLESEYQQLRDLSAGRMLDLDSLIAFVRAAQLELIWVSERESIEVTRNWSDIKQLDLPMLTNYYKQLLHEMELREKQYNDVHNQGAALLNQGHPAIRVIEVYLRQMQSQWDWLLALSKCLEEHLRDALNLKSFMEEASDAEAWIQEQSVRLENNYNRT-DFSLEEGERFLRELDEIKEILNKYHQVLMALTERCASISPLWQRGERI-PHP-IKVTALCDYSDENVTIKA-----GDDVYLLDNSDLIKWTIRDISGAEGQVPSVVFRIPPTDARLTALLNRLLQQFEKLKKLWDKKHRMVRFNMVLNTMRTIQGWDLDTFNSIDPDQRDAIMKALNDDANKLLSEL-----DPNDPLALRLREELRRTNEHFWNLLNA----------SQKPPEPDWA------SQYDQKMAELLKKLEEAWRELNDAVGKPISRSPEDLERVIHAHKRFEDALQALDSDVANVKELFRQLPNPTPTQRVNHDRLNGLWDDLWDLSRMYVERIKVLESVLNGMVEVADIVRQHEITL-NSFDDLPAALDKLRGHHSQLLEINMVLKVSKLGAQNEHFSQQQTVIDQLNRNVALLRQHVSRTRINEG--HHPDVDAIEDEVQKLNVRWENVNSQIASRLLAVESALQIQMVYRSEYETEMSWLDTVEETI-NRLRKPEELRPEQYQQQLDMLIAEYTNLQ----EHTQAIEHVNKEGGRFIHEAKIFDAKLGQYSDGIVGIHGPGIKSEFRRTK 1317
BLAST of Dystonin vs. Ensembl Celegans
Match: vab-10 (VAB-10B protein [Source:UniProtKB/TrEMBL;Acc:G5EFM4]) HSP 1 Score: 445.277 bits (1144), Expect = 3.959e-124 Identity = 509/2233 (22.79%), Postives = 1005/2233 (45.01%), Query Frame = 3 Query: 12957 QKVDPLKKQLE---ELIDIGNKACSTVISGLGFKHMEQEMDS----VKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLIN-TKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSP-TVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVD--PYQTRDIWEESLNLVKE----VKSHEETLKNLDQVGEDLKQISSENDSAAI-NCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNME---ILENETN-----SVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQ--APGSDL-KSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQN-KINNLDPD----QLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNI--DRQQSLITKLEEMRM------KLDEWFKEVNNRLFILGPLPTETRPVLTQI-QKTKEL---KNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMI--RADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRF----MDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWL-RAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQ-YNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF------KFKPAT-LPIPTKK---------PTTAKIPSPRVSQPLSSPRIH---QPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTP----KVVASPGLQRKSRIPT 19421 +KV LK+ L+ E +D N C +I G + +E+DS V ++ ++ VSD E VD + ++ K + + L ++E ++ ++PS + +K+QL+ + +L+ ++ ++ S+D ++ + + +K L N+ ++ +Y++LLN A + + AV L++ ++ P WL +A+K L P TV+ + E+ I E + LQ++ ++ LK ++ ++ + + VS++ N I+ ++ ++ + + + L + + F ++KL +D P + D+ E++ N++ E + +E + N+ +VG+ L I E + A I K++ L + ++ SA +K++L +IP++E F + D V+ L + R+ ++ + E E +LE + + SV++L + N L L S D ++++ + K V + V ++A +I +++ ++L +E S ++I E + + S+L+ +I TN ++ N K + ++KK+ RQ G++ + + VD K+ E + + L+ A+ L ++ S ++ L WL + + + + + P ++H +E+ + ++ +P+++ L +++ Q + + + + Y ++E ++ R +++++ E+++ L+ DR+ ++ S P L+ L I+ L Q D L ++ A++ S D+ + K N LEKL K ++ + ++ + ++L A FW++L + ++ L + + D+++++ + E++ I +S GKQL + V PD E+A ++ VR IT + ++++ LI +EE +L +W +L + P+ E +T+I Q KEL K+++ + E + QL + P++ V +A +N W+RL L +R+H+L+ ++L +G+ + + W+ T +L +I +N ++ +AQ K++ D++ Q SV+ + R A + I+ +L E + L+ + WE++++ + F++E A KEA G+ ++ + ++E S L K +GGLP+TA+ QL F +D+ L + + E + + + K + KW+ VK L R+ +L+ A E + +W+ E+ L Q +SR+ I +Q+ H + ++ + M H++Y +K D + I+N + S+ HR EK+ R++ER++ L E ++D L I+ L + + + + K++ ++ + KE ++ +D TR+ G L ++A + K+I + KW + K +R + A+L G ++++M +L SW+ +E + D++ V+ L++E S + + +++ ++ + A ALM ++ I L WN V + A + ++EA+ A EF+ ++L ++ + E +L+ + +E E + M G + + L + G EIL P AE +++++ +++++W ++ ++R L + + E+ A + EL+ + + Q + E+ I D + + +++ P + +K+ N P L ++WK++W + + L + L+E++ ++ + +EDW+ RY+ W +H+K+RV D FRR D H G V R+ FIDGII SKF T+R+EM VAD FDK G I+ ++F+ ALR D KP + E I E++ Q C+C PY+I + + Y+FGDT R+VRILRS VMVR+GGGW +LDEFL KHDPCR AKGR N + + + P +++M F K P T P P K P + + + H +P PR P +++ R+S+ S S+ TP +S R++RIP+ Sbjct: 2802 EKVRQLKESLKPVGEKMDAFNTDCKLLIKTAGPESDTKELDSLLKKVGDAYSDVVGKVSDKEMSVDAAVQQQGKVEDAYRALLNWLEETEEMMENRKKPSADAKVAKAQLHDYEVLMKHVEDKKPSVDGFKAMIEKIVAEASSDEEKKALGNKNAQIEDRYKDLLNSAVDRQRKLLDAVDLAERLQEVTIPLDSWLQSADKRLQALAKVPITVE--KAEEMIGEQEALQDE---LEHKSDDLKDVL-EIAPMLASLVSVEDANSISGQVNQLEARARALDAGITNMRPLLESFLQQIQDFTLDAEDMTQF-VGETEVKLGELDELPIEPDDLVEQT-NILAEIAVSIADRDEMMANIFEVGKQLA-IQGEPEEALIAQKKLDDLKFRYADLMTSADEKIALLAKAIPLSEGF---HEGFDTVMQVLEDMDRDLQTIDEEDPETQAELIFLLEEDISQKMRPSVDELTALS-NQLQVLCSAD----KADELQTNTIAMNKLVNSVADRVARRAERIEMASKQSRAVLDDLQYLIEWFSAARERILEGAPPSLDLEVLKSQLKHQRI--TNEEASAN--KVQFRNVAGEAKKVARQLGMEGNEANEKISDTVDEGKELVEEVMALCADRTETLERALALMEQLTSQFDELNKWLDQMDAELQASPSVTTATPAAELREMHDHNEELARMVAAY---RPIIEGFKSDVGSLHEVLAEDQAPLLESVAGELVQGYEEVREAVRARGHAIDNMMGATIGFGERLETLVANLQGAADRLRENEGISADPSVLESRLAENRSIVESLRDKQNAYDAL----------KQTASELLASAPEGDAAAGDVENKLNRLEKLW------KEIEREAVDRGVLLEDVLDKAKHFWSELDSCQKAVDDLRNRLELVEPATGHPEQLADQQEIMAQVASEMERARPRIEALSIAGKQLADYV------PDDEKA--VIENQVANVRGGF-STITGLFAEKKRDLIAAMEEAMTFHGDLQELLKWLDMAEQKLLKMSPV--EHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQLAADAPPHLAATVRQPVADLNTRWSRLNAALAEREHKLENLMLQMGKLASTIAQLTAWMDKTRATLKDIAPPKNAVNLRDIEIAQCKLVVLSNDIHAHQDSVNAVNRAAQKYIQTS-GALDAETSDSLKSMNLKWEDIQKVLESLAFDMEVAKKEAENVGGEVEKWQRWLEETESALLSTKPTGGLPETAEFQLDEFKALKLDVEHNASPLEAHLHATEQHLKEEPQDADTWLSKT----HGAMKTKWNKVKELLVDREKKLQVAYEQAVALESALNDMEDWIIAAERKLTDQPSISRLPDVIEKQLAEHESWMEEVAGRKMAMTKHQASGVHMQYYCEKKDAIPIKNRLVSLKHRVEKISGRTAERAKQLAVTRDEVATWQDGLHDLEHFISDVLVKIAPEPNTTSSLEKLKAKLEEVKEAQRDVTAKQTLFDVTRKRGIGLAERATRSEYKQISMTNEKMSKKWAEMLKKLRDRLREAEQAVLEGGAFEESMNDLESWVDDELERYQKAEHEPVFADIDGVRALVDEESRRSAERKTKENGVKTVVKKADALMASGVDEKDSIAQAKERLVEKWNQVEEAARHRGNSIKEAEQAAEEFDAKTHALLDWLAVEEQKLKASGL---DEVEGVKQEMDEAKGRYQECL-----------KKGEEILSKCQPAAEPILRNWMRVVEARWKEVSEKVDEREFTLLEQEQKAKEQN--------EQIEKLAKFAAQKREELNRMIEQPPAQDLDTMEQNICDFA-------NLDSELREQQPEVDAACKSAKKGARN-------------PAAEMLSTEWKKLWLDAMGLQSSLDNQKALLEEMKRLEGWKWEDWKERYVEWNDHAKARVNDLFRRIDRLHTGNVPRQVFIDGIIGSKFPTSRLEMAKVADRFDK-GDGMINAKEFINALRFDASNRNAKPQTDTEKITHEIELQKKTCSCCTPYQIEKISENHYRFGDTHIKRMVRILRSTVMVRVGGGWESLDEFLHKHDPCR----------------------AKGRLNINMFPE-ARPIHALDSMRSFTKNRHGKQLPTTGTPGPIMKIREKTDRSVPMSGGLGGTAGYTVTTDSHRHTDARPSRIPRAPSDMSAGRLSRVGSVSNSKNSIVDSSTPSRPESRASSDAGDRQTRIPS 4912 HSP 2 Score: 354.369 bits (908), Expect = 1.125e-96 Identity = 337/1330 (25.34%), Postives = 616/1330 (46.32%), Query Frame = 3 Query: 405 DERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQ------------SSK------------SDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQ--QNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIE----------EKIYQFRN------QYADLYANLNSALEELNDDFDHNDFRIDFNQTRLENNYLTYLKQYESFCHLFDDISKVDRNNENQRKFHTIST-----LWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDGYP-ADQHYRIIININGK----IDKVKKKFEKLSPPTLSSGVISNRQYTPIHSMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLDGLNKIYEKFSTTFNEIKD---SVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICS-SKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANIDENE--INKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKDVPTNLDQLISAVTTSRQNQK-----DVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFE---SKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYEDIFKNYQNEIQNQIGGSNQDYFGYTK 4196 DERD +QK+TF W+N HL K + ++ D+F DLRDG L+ LLE L+ +++ +N +RFH ++N+ LDFL+ +NIKLVNI ED+V+GN KLTLGL+W IIL FQ I Q S+K SD S + LLQW+R+ YP +N+ NFS+SW+DG AF A++H+ R ID IS +S + L AF A +E GV ++++ EDV + DEKS++TYV+SL+ P E ++ E+ Y++R Q D +L EL ++ FR D R E Q +++ + KV R+ E H +S +W++ + + + +L + S + L K++ I +I + + +P + ++ I +L E+ I V+ELK +P A+ Y+ + ++ + +D++ + L + + + + +M +S + + W+ + ++ + F DL+ L ++E+ +I+D +VDE + ++E + ++ + L++++ +L + D S + F+ + + W+ +E ++ W D + + L +K L+ E+E+RE N+ G L H A I+ L ++S+W W+L L+ CL+ HL + F EA++A+ I E + +L + + R L+EGE RE+ ++ E + Y + + + S+S L R I P + V A+C S EN G+ + L +NS W + + P++ F I + + L F LK LW K+ +R ++L+TM ++ W + F +++P R I++ LN DAN+L+ +L D N+ + L + N F L ++ S + P A + D ++ +L+ + +EL+ + P+ + LE + HK FE L+ + V ++ + + T +V +R+ LW+ LW+ + M+V ++K E + + E+ ++ + E+TL N + PA +D+++ +QL I+ V LK T +DQL V RQ+ + + D+ ++ E++ + R+E + +QI RL V + ++E + +W+ ++ T+ +++ P + + ++ L+ + N Q ++ I+ +NK F++ + ++ Y + I G + F TK Sbjct: 35 DERDNVQKKTFTKWVNKHLSKTDHKIDDLFVDLRDGYALIALLEALTGERIQKENGYTRFHRIQNVQYCLDFLKKKNIKLVNIRPEDIVEGNGKLTLGLIWTIILNFQVSVIRQRLLLESSQHEQMSAKHTTTNSQVSLHGSDATSARDALLQWARRVTAGYPRVNVNNFSSSWRDGLAFNAILHRYRSSAIDWNKISSDSVSNTERLNNAFAAADREFGVERLLDAEDVDTNNPDEKSIITYVSSLYNALPHEPEMSRLQKVQEEYIEEAYEWREWVVRAIQLVD-DRHLQGTASELI--YELQRFREDDLPPREE--------QKRRLTLVYEHLEKVMRSTELFAIPHELSAPELQRVWNELQNSIDRRFDVLERHRIQEGNSNDLLSRLARGIGITNEKLDLILKRIEDVEARVDTSPPAAVERTVSEIVDDLNALESPIARFFEDVEELKSMQHPEANDFYKQVYGLHQRRTTYLDRLTNQI--LVRLGVRTDSLHKENQQRLENMR---KTSFSRVEECIEWVRVRMEKLTTMEFLEDLETLEHVFEQHKFDNRDIQDFRQNVDEC-IARQAEVSAEDTYEYCELLRVLESEYQQLRDLSAGRMLDLDSLIAFVRAAQLELIWVSERESIEVTRNWSDIKQLDLPMLTNYYKQLLHEMELREKQYNDVHNQGAALLNQGHPAIRVIEVYLRQMQSQWDWLLALSKCLEEHLRDALNLKSFMEEASDAEAWIQEQSVRLENNYNR-TDFSLEEGERFLRELDEIKEILNKYHQVLMALTERCASISPLWQRGERI-PHP-IKVTALCDYSDENVTIKA-----GDDVYLLDNSDLIKWTIRDISGAEGQVPSVVFRIPPTDARLTALLNRLLQQFEKLKKLWDKKHRMVRFNMVLNTMRTIQGWDLDTFNSIDPDQRDAIMKALNDDANKLLSEL-----DPNDPLALRLREELRRTNEHFWNLLNA----------SQKPPEPDWA------SQYDQKMAELLKKLEEAWRELNDAVGKPISRSPEDLERVIHAHKRFEDALQALDSDVANVKELFRQLPNPTPTQRVNHDRLNGLWDDLWDLSRMYVERIKVLESVLNGMVEVADIVRQHEITL-NSFDDLPAALDKLRGHHSQLL----EINMV---LKQQQTVIDQLNRNVALLRQHVSRTRINEGHHPDVDAIEDEVQKLNVRWENVNSQIASRLLAVESALQIQMVYRSEYETEMSWLDTVEETI-NRLRKPEELRPEQYQQQLDMLIAEYTNLQ----EHTQAIEHVNKEGGRFIHEAKIFDAKLGQYSDGIVGIHGPGIKSEFRRTK 1305
BLAST of Dystonin vs. Ensembl Celegans
Match: vab-10 (VAB-10B protein [Source:UniProtKB/TrEMBL;Acc:G5EFM4]) HSP 1 Score: 444.891 bits (1143), Expect = 4.958e-124 Identity = 509/2233 (22.79%), Postives = 1005/2233 (45.01%), Query Frame = 3 Query: 12957 QKVDPLKKQLE---ELIDIGNKACSTVISGLGFKHMEQEMDS----VKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLIN-TKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSP-TVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVD--PYQTRDIWEESLNLVKE----VKSHEETLKNLDQVGEDLKQISSENDSAAI-NCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNME---ILENETN-----SVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQ--APGSDL-KSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQN-KINNLDPD----QLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNI--DRQQSLITKLEEMRM------KLDEWFKEVNNRLFILGPLPTETRPVLTQI-QKTKEL---KNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMI--RADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRF----MDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWL-RAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQ-YNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF------KFKPAT-LPIPTKK---------PTTAKIPSPRVSQPLSSPRIH---QPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTP----KVVASPGLQRKSRIPT 19421 +KV LK+ L+ E +D N C +I G + +E+DS V ++ ++ VSD E VD + ++ K + + L ++E ++ ++PS + +K+QL+ + +L+ ++ ++ S+D ++ + + +K L N+ ++ +Y++LLN A + + AV L++ ++ P WL +A+K L P TV+ + E+ I E + LQ++ ++ LK ++ ++ + + VS++ N I+ ++ ++ + + + L + + F ++KL +D P + D+ E++ N++ E + +E + N+ +VG+ L I E + A I K++ L + ++ SA +K++L +IP++E F + D V+ L + R+ ++ + E E +LE + + SV++L + N L L S D ++++ + K V + V ++A +I +++ ++L +E S ++I E + + S+L+ +I TN ++ N K + ++KK+ RQ G++ + + VD K+ E + + L+ A+ L ++ S ++ L WL + + + + + P ++H +E+ + ++ +P+++ L +++ Q + + + + Y ++E ++ R +++++ E+++ L+ DR+ ++ S P L+ L I+ L Q D L ++ A++ S D+ + K N LEKL K ++ + ++ + ++L A FW++L + ++ L + + D+++++ + E++ I +S GKQL + V PD E+A ++ VR IT + ++++ LI +EE +L +W +L + P+ E +T+I Q KEL K+++ + E + QL + P++ V +A +N W+RL L +R+H+L+ ++L +G+ + + W+ T +L +I +N ++ +AQ K++ D++ Q SV+ + R A + I+ +L E + L+ + WE++++ + F++E A KEA G+ ++ + ++E S L K +GGLP+TA+ QL F +D+ L + + E + + + K + KW+ VK L R+ +L+ A E + +W+ E+ L Q +SR+ I +Q+ H + ++ + M H++Y +K D + I+N + S+ HR EK+ R++ER++ L E ++D L I+ L + + + + K++ ++ + KE ++ +D TR+ G L ++A + K+I + KW + K +R + A+L G ++++M +L SW+ +E + D++ V+ L++E S + + +++ ++ + A ALM ++ I L WN V + A + ++EA+ A EF+ ++L ++ + E +L+ + +E E + M G + + L + G EIL P AE +++++ +++++W ++ ++R L + + E+ A + EL+ + + Q + E+ I D + + +++ P + +K+ N P L ++WK++W + + L + L+E++ ++ + +EDW+ RY+ W +H+K+RV D FRR D H G V R+ FIDGII SKF T+R+EM VAD FDK G I+ ++F+ ALR D KP + E I E++ Q C+C PY+I + + Y+FGDT R+VRILRS VMVR+GGGW +LDEFL KHDPCR AKGR N + + + P +++M F K P T P P K P + + + H +P PR P +++ R+S+ S S+ TP +S R++RIP+ Sbjct: 2689 EKVRQLKESLKPVGEKMDAFNTDCKLLIKTAGPESDTKELDSLLKKVGDAYSDVVGKVSDKEMSVDAAVQQQGKVEDAYRALLNWLEETEEMMENRKKPSADAKVAKAQLHDYEVLMKHVEDKKPSVDGFKAMIEKIVAEASSDEEKKALGNKNAQIEDRYKDLLNSAVDRQRKLLDAVDLAERLQEVTIPLDSWLQSADKRLQALAKVPITVE--KAEEMIGEQEALQDE---LEHKSDDLKDVL-EIAPMLASLVSVEDANSISGQVNQLEARARALDAGITNMRPLLESFLQQIQDFTLDAEDMTQF-VGETEVKLGELDELPIEPDDLVEQT-NILAEIAVSIADRDEMMANIFEVGKQLA-IQGEPEEALIAQKKLDDLKFRYADLMTSADEKIALLAKAIPLSEGF---HEGFDTVMQVLEDMDRDLQTIDEEDPETQAELIFLLEEDISQKMRPSVDELTALS-NQLQVLCSAD----KADELQTNTIAMNKLVNSVADRVARRAERIEMASKQSRAVLDDLQYLIEWFSAARERILEGAPPSLDLEVLKSQLKHQRI--TNEEASAN--KVQFRNVAGEAKKVARQLGMEGNEANEKISDTVDEGKELVEEVMALCADRTETLERALALMEQLTSQFDELNKWLDQMDAELQASPSVTTATPAAELREMHDHNEELARMVAAY---RPIIEGFKSDVGSLHEVLAEDQAPLLESVAGELVQGYEEVREAVRARGHAIDNMMGATIGFGERLETLVANLQGAADRLRENEGISADPSVLESRLAENRSIVESLRDKQNAYDAL----------KQTASELLASAPEGDAAAGDVENKLNRLEKLW------KEIEREAVDRGVLLEDVLDKAKHFWSELDSCQKAVDDLRNRLELVEPATGHPEQLADQQEIMAQVASEMERARPRIEALSIAGKQLADYV------PDDEKA--VIENQVANVRGGF-STITGLFAEKKRDLIAAMEEAMTFHGDLQELLKWLDMAEQKLLKMSPV--EHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQLAADAPPHLAATVRQPVADLNTRWSRLNAALAEREHKLENLMLQMGKLASTIAQLTAWMDKTRATLKDIAPPKNAVNLRDIEIAQCKLVVLSNDIHAHQDSVNAVNRAAQKYIQTS-GALDAETSDSLKSMNLKWEDIQKVLESLAFDMEVAKKEAENVGGEVEKWQRWLEETESALLSTKPTGGLPETAEFQLDEFKALKLDVEHNASPLEAHLHATEQHLKEEPQDADTWLSKT----HGAMKTKWNKVKELLVDREKKLQVAYEQAVALESALNDMEDWIIAAERKLTDQPSISRLPDVIEKQLAEHESWMEEVAGRKMAMTKHQASGVHMQYYCEKKDAIPIKNRLVSLKHRVEKISGRTAERAKQLAVTRDEVATWQDGLHDLEHFISDVLVKIAPEPNTTSSLEKLKAKLEEVKEAQRDVTAKQTLFDVTRKRGIGLAERATRSEYKQISMTNEKMSKKWAEMLKKLRDRLREAEQAVLEGGAFEESMNDLESWVDDELERYQKAEHEPVFADIDGVRALVDEESRRSAERKTKENGVKTVVKKADALMASGVDEKDSIAQAKERLVEKWNQVEEAARHRGNSIKEAEQAAEEFDAKTHALLDWLAVEEQKLKASGL---DEVEGVKQEMDEAKGRYQECL-----------KKGEEILSKCQPAAEPILRNWMRVVEARWKEVSEKVDEREFTLLEQEQKAKEQN--------EQIEKLAKFAAQKREELNRMIEQPPAQDLDTMEQNICDFA-------NLDSELREQQPEVDAACKSAKKGARN-------------PAAEMLSTEWKKLWLDAMGLQSSLDNQKALLEEMKRLEGWKWEDWKERYVEWNDHAKARVNDLFRRIDRLHTGNVPRQVFIDGIIGSKFPTSRLEMAKVADRFDK-GDGMINAKEFINALRFDASNRNAKPQTDTEKITHEIELQKKTCSCCTPYQIEKISENHYRFGDTHIKRMVRILRSTVMVRVGGGWESLDEFLHKHDPCR----------------------AKGRLNINMFPE-ARPIHALDSMRSFTKNRHGKQLPTTGTPGPIMKIREKTDRSVPMSGGLGGTAGYTVTTDSHRHTDARPSRIPRAPSDMSAGRLSRVGSVSNSKNSIVDSSTPSRPESRASSDAGDRQTRIPS 4799 HSP 2 Score: 206.453 bits (524), Expect = 5.338e-52 Identity = 122/325 (37.54%), Postives = 186/325 (57.23%), Query Frame = 3 Query: 405 DERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQ------------SSK------------SDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQ--QNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKIYQFRNQYADLYANLNSALEELNDDFDHNDFRIDFNQTRLENNYLTYLKQYESFCHLFDDISKVD 1301 DERD +QK+TF W+N HL K + ++ D+F DLRDG L+ LLE L+ +++ +N +RFH ++N+ LDFL+ +NIKLVNI ED+V+GN KLTLGL+W IIL FQ I Q S+K SD S + LLQW+R+ YP +N+ NFS+SW+DG AF A++H+ R ID IS +S + L AF A +E GV ++++ EDV + DEKS++TYV+SL+ P E ++ R DL + L + N+ D RI+ + R++ + +++ + + DD++ ++ Sbjct: 35 DERDNVQKKTFTKWVNKHLSKTDHKIDDLFVDLRDGYALIALLEALTGERIQKENGYTRFHRIQNVQYCLDFLKKKNIKLVNIRPEDIVEGNGKLTLGLIWTIILNFQVSVIRQRLLLESSQHEQMSAKHTTTNSQVSLHGSDATSARDALLQWARRVTAGYPRVNVNNFSSSWRDGLAFNAILHRYRSSAIDWNKISSDSVSNTERLNNAFAAADREFGVERLLDAEDVDTNNPDEKSIITYVSSLYNALPHEPEMS------RGNSNDLLSRLARGIGITNEKLDLILKRIEDVEARVDTSPPAAVER--TVSEIVDDLNALE 351 HSP 3 Score: 171.785 bits (434), Expect = 1.608e-41 Identity = 184/812 (22.66%), Postives = 367/812 (45.20%), Query Frame = 3 Query: 1803 YSSLNKWKNWIDEKCAIISEINFTNDLDGLNKIYEKFSTTFNEIKD---SVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICS-SKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANIDENE--INKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKDVPTNLDQLISAVTTSRQNQK-----DVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFE---SKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYEDIFKNYQNEIQNQIGGSNQDYFGYTK 4196 +S + + W+ + ++ + F DL+ L ++E+ +I+D +VDE + ++E + ++ + L++++ +L + D S + F+ + + W+ +E ++ W D + + L +K L+ E+E+RE N+ G L H A I+ L ++S+W W+L L+ CL+ HL + F EA++A+ I E + +L + + R L+EGE RE+ ++ E + Y + + + S+S L R I P + V A+C S EN G+ + L +NS W + + P++ F I + + L F LK LW K+ +R ++L+TM ++ W + F +++P R I++ LN DAN+L+ +L D N+ + L + N F L ++ S + P A + D ++ +L+ + +EL+ + P+ + LE + HK FE L+ + V ++ + + T +V +R+ LW+ LW+ + M+V ++K E + + E+ ++ + E+TL N + PA +D+++ +QL I+ V LK T +DQL V RQ+ + + D+ ++ E++ + R+E + +QI RL V + ++E + +W+ ++ T+ +++ P + + ++ L+ + N Q ++ I+ +NK F++ + ++ Y + I G + F TK Sbjct: 424 FSRVEECIEWVRVRMEKLTTMEFLEDLETLEHVFEQHKFDNRDIQDFRQNVDEC-IARQAEVSAEDTYEYCELLRVLESEYQQLRDLSAGRMLDLDSLIAFVRAAQLELIWVSERESIEVTRNWSDIKQLDLPMLTNYYKQLLHEMELREKQYNDVHNQGAALLNQGHPAIRVIEVYLRQMQSQWDWLLALSKCLEEHLRDALNLKSFMEEASDAEAWIQEQSVRLENNYNRT-DFSLEEGERFLRELDEIKEILNKYHQVLMALTERCASISPLWQRGERI-PHP-IKVTALCDYSDENVTIKA-----GDDVYLLDNSDLIKWTIRDISGAEGQVPSVVFRIPPTDARLTALLNRLLQQFEKLKKLWDKKHRMVRFNMVLNTMRTIQGWDLDTFNSIDPDQRDAIMKALNDDANKLLSEL-----DPNDPLALRLREELRRTNEHFWNLLNA----------SQKPPEPDWA------SQYDQKMAELLKKLEEAWRELNDAVGKPISRSPEDLERVIHAHKRFEDALQALDSDVANVKELFRQLPNPTPTQRVNHDRLNGLWDDLWDLSRMYVERIKVLESVLNGMVEVADIVRQHEITL-NSFDDLPAALDKLRGHHSQLL----EINMV---LKQQQTVIDQLNRNVALLRQHVSRTRINEGHHPDVDAIEDEVQKLNVRWENVNSQIASRLLAVESALQIQMVYRSEYETEMSWLDTVEETI-NRLRKPEELRPEQYQQQLDMLIAEYTNLQ----EHTQAIEHVNKEGGRFIHEAKIFDAKLGQYSDGIVGIHGPGIKSEFRRTK 1192
BLAST of Dystonin vs. Ensembl Celegans
Match: vab-10 (VAB-10B protein [Source:UniProtKB/TrEMBL;Acc:G5EFM4]) HSP 1 Score: 444.121 bits (1141), Expect = 9.325e-124 Identity = 509/2233 (22.79%), Postives = 1005/2233 (45.01%), Query Frame = 3 Query: 12957 QKVDPLKKQLE---ELIDIGNKACSTVISGLGFKHMEQEMDS----VKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLIN-TKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSP-TVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVD--PYQTRDIWEESLNLVKE----VKSHEETLKNLDQVGEDLKQISSENDSAAI-NCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNME---ILENETN-----SVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQ--APGSDL-KSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQN-KINNLDPD----QLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNI--DRQQSLITKLEEMRM------KLDEWFKEVNNRLFILGPLPTETRPVLTQI-QKTKEL---KNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMI--RADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRF----MDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWL-RAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQ-YNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF------KFKPAT-LPIPTKK---------PTTAKIPSPRVSQPLSSPRIH---QPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTP----KVVASPGLQRKSRIPT 19421 +KV LK+ L+ E +D N C +I G + +E+DS V ++ ++ VSD E VD + ++ K + + L ++E ++ ++PS + +K+QL+ + +L+ ++ ++ S+D ++ + + +K L N+ ++ +Y++LLN A + + AV L++ ++ P WL +A+K L P TV+ + E+ I E + LQ++ ++ LK ++ ++ + + VS++ N I+ ++ ++ + + + L + + F ++KL +D P + D+ E++ N++ E + +E + N+ +VG+ L I E + A I K++ L + ++ SA +K++L +IP++E F + D V+ L + R+ ++ + E E +LE + + SV++L + N L L S D ++++ + K V + V ++A +I +++ ++L +E S ++I E + + S+L+ +I TN ++ N K + ++KK+ RQ G++ + + VD K+ E + + L+ A+ L ++ S ++ L WL + + + + + P ++H +E+ + ++ +P+++ L +++ Q + + + + Y ++E ++ R +++++ E+++ L+ DR+ ++ S P L+ L I+ L Q D L ++ A++ S D+ + K N LEKL K ++ + ++ + ++L A FW++L + ++ L + + D+++++ + E++ I +S GKQL + V PD E+A ++ VR IT + ++++ LI +EE +L +W +L + P+ E +T+I Q KEL K+++ + E + QL + P++ V +A +N W+RL L +R+H+L+ ++L +G+ + + W+ T +L +I +N ++ +AQ K++ D++ Q SV+ + R A + I+ +L E + L+ + WE++++ + F++E A KEA G+ ++ + ++E S L K +GGLP+TA+ QL F +D+ L + + E + + + K + KW+ VK L R+ +L+ A E + +W+ E+ L Q +SR+ I +Q+ H + ++ + M H++Y +K D + I+N + S+ HR EK+ R++ER++ L E ++D L I+ L + + + + K++ ++ + KE ++ +D TR+ G L ++A + K+I + KW + K +R + A+L G ++++M +L SW+ +E + D++ V+ L++E S + + +++ ++ + A ALM ++ I L WN V + A + ++EA+ A EF+ ++L ++ + E +L+ + +E E + M G + + L + G EIL P AE +++++ +++++W ++ ++R L + + E+ A + EL+ + + Q + E+ I D + + +++ P + +K+ N P L ++WK++W + + L + L+E++ ++ + +EDW+ RY+ W +H+K+RV D FRR D H G V R+ FIDGII SKF T+R+EM VAD FDK G I+ ++F+ ALR D KP + E I E++ Q C+C PY+I + + Y+FGDT R+VRILRS VMVR+GGGW +LDEFL KHDPCR AKGR N + + + P +++M F K P T P P K P + + + H +P PR P +++ R+S+ S S+ TP +S R++RIP+ Sbjct: 2929 EKVRQLKESLKPVGEKMDAFNTDCKLLIKTAGPESDTKELDSLLKKVGDAYSDVVGKVSDKEMSVDAAVQQQGKVEDAYRALLNWLEETEEMMENRKKPSADAKVAKAQLHDYEVLMKHVEDKKPSVDGFKAMIEKIVAEASSDEEKKALGNKNAQIEDRYKDLLNSAVDRQRKLLDAVDLAERLQEVTIPLDSWLQSADKRLQALAKVPITVE--KAEEMIGEQEALQDE---LEHKSDDLKDVL-EIAPMLASLVSVEDANSISGQVNQLEARARALDAGITNMRPLLESFLQQIQDFTLDAEDMTQF-VGETEVKLGELDELPIEPDDLVEQT-NILAEIAVSIADRDEMMANIFEVGKQLA-IQGEPEEALIAQKKLDDLKFRYADLMTSADEKIALLAKAIPLSEGF---HEGFDTVMQVLEDMDRDLQTIDEEDPETQAELIFLLEEDISQKMRPSVDELTALS-NQLQVLCSAD----KADELQTNTIAMNKLVNSVADRVARRAERIEMASKQSRAVLDDLQYLIEWFSAARERILEGAPPSLDLEVLKSQLKHQRI--TNEEASAN--KVQFRNVAGEAKKVARQLGMEGNEANEKISDTVDEGKELVEEVMALCADRTETLERALALMEQLTSQFDELNKWLDQMDAELQASPSVTTATPAAELREMHDHNEELARMVAAY---RPIIEGFKSDVGSLHEVLAEDQAPLLESVAGELVQGYEEVREAVRARGHAIDNMMGATIGFGERLETLVANLQGAADRLRENEGISADPSVLESRLAENRSIVESLRDKQNAYDAL----------KQTASELLASAPEGDAAAGDVENKLNRLEKLW------KEIEREAVDRGVLLEDVLDKAKHFWSELDSCQKAVDDLRNRLELVEPATGHPEQLADQQEIMAQVASEMERARPRIEALSIAGKQLADYV------PDDEKA--VIENQVANVRGGF-STITGLFAEKKRDLIAAMEEAMTFHGDLQELLKWLDMAEQKLLKMSPV--EHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQLAADAPPHLAATVRQPVADLNTRWSRLNAALAEREHKLENLMLQMGKLASTIAQLTAWMDKTRATLKDIAPPKNAVNLRDIEIAQCKLVVLSNDIHAHQDSVNAVNRAAQKYIQTS-GALDAETSDSLKSMNLKWEDIQKVLESLAFDMEVAKKEAENVGGEVEKWQRWLEETESALLSTKPTGGLPETAEFQLDEFKALKLDVEHNASPLEAHLHATEQHLKEEPQDADTWLSKT----HGAMKTKWNKVKELLVDREKKLQVAYEQAVALESALNDMEDWIIAAERKLTDQPSISRLPDVIEKQLAEHESWMEEVAGRKMAMTKHQASGVHMQYYCEKKDAIPIKNRLVSLKHRVEKISGRTAERAKQLAVTRDEVATWQDGLHDLEHFISDVLVKIAPEPNTTSSLEKLKAKLEEVKEAQRDVTAKQTLFDVTRKRGIGLAERATRSEYKQISMTNEKMSKKWAEMLKKLRDRLREAEQAVLEGGAFEESMNDLESWVDDELERYQKAEHEPVFADIDGVRALVDEESRRSAERKTKENGVKTVVKKADALMASGVDEKDSIAQAKERLVEKWNQVEEAARHRGNSIKEAEQAAEEFDAKTHALLDWLAVEEQKLKASGL---DEVEGVKQEMDEAKGRYQECL-----------KKGEEILSKCQPAAEPILRNWMRVVEARWKEVSEKVDEREFTLLEQEQKAKEQN--------EQIEKLAKFAAQKREELNRMIEQPPAQDLDTMEQNICDFA-------NLDSELREQQPEVDAACKSAKKGARN-------------PAAEMLSTEWKKLWLDAMGLQSSLDNQKALLEEMKRLEGWKWEDWKERYVEWNDHAKARVNDLFRRIDRLHTGNVPRQVFIDGIIGSKFPTSRLEMAKVADRFDK-GDGMINAKEFINALRFDASNRNAKPQTDTEKITHEIELQKKTCSCCTPYQIEKISENHYRFGDTHIKRMVRILRSTVMVRVGGGWESLDEFLHKHDPCR----------------------AKGRLNINMFPE-ARPIHALDSMRSFTKNRHGKQLPTTGTPGPIMKIREKTDRSVPMSGGLGGTAGYTVTTDSHRHTDARPSRIPRAPSDMSAGRLSRVGSVSNSKNSIVDSSTPSRPESRASSDAGDRQTRIPS 5039 HSP 2 Score: 249.595 bits (636), Expect = 4.993e-65 Identity = 276/1197 (23.06%), Postives = 533/1197 (44.53%), Query Frame = 3 Query: 732 KDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQ--QNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIE----------EKIYQFRN------QYADLYANLNSALEELNDDFDHNDFRIDFNQTRLENNYLTYLKQYESFCHLFDDISKVDRNNENQRKFHTIST-----LWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDGYP-ADQHYRIIININGK----IDKVKKKFEKLSPPTLSSGVISNRQYTPIHSMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLDGLNKIYEKFSTTFNEIKD---SVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICS-SKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANIDENE--INKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKDVPTNLDQLISAVTTSRQNQK-----DVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFE---SKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYEDIFKNYQNEIQNQIGGSNQDYFGYTK 4196 +D V SD S + LLQW+R+ YP +N+ NFS+SW+DG AF A++H+ R ID IS +S + L AF A +E GV ++++ EDV + DEKS++TYV+SL+ P E ++ E+ Y++R Q D +A E + ++ FR D R E Q +++ + KV R+ E H +S +W++ + + + +L + S + L K++ I +I + + +P + ++ I +L E+ I V+ELK +P A+ Y+ + ++ + +D++ + L + + + + +M +S + + W+ + ++ + F DL+ L ++E+ +I+D +VDE + ++E + ++ + L++++ +L + D S + F+ + + W+ +E ++ W D + + L +K L+ E+E+RE N+ G L H A I+ L ++S+W W+L L+ CL+ HL + F EA++A+ I E + +L + + R L+EGE RE+ ++ E + Y + + + S+S L R I P + V A+C S EN G+ + L +NS W + + P++ F I + + L F LK LW K+ +R ++L+TM ++ W + F +++P R I++ LN DAN+L+ +L D N+ + L + N F L N S P + + + D ++ +L+ + +EL+ + P+ + LE + HK FE L+ + V ++ + + T +V +R+ LW+ LW+ + M+V ++K E + + E+ ++ + E+TL N + PA +D+++ +QL I+ V LK T +DQL V RQ+ + + D+ ++ E++ + R+E + +QI RL V + ++E + +W+ ++ T+ +++ P + + ++ L+ + N Q ++ I+ +NK F++ + ++ Y + I G + F TK Sbjct: 295 RDDVSLHGSDATSARDALLQWARRVTAGYPRVNVNNFSSSWRDGLAFNAILHRYRSSAIDWNKISSDSVSNTERLNNAFAAADREFGVERLLDAEDVDTNNPDEKSIITYVSSLYNALPHEPEMSRLQKVQEEYIEEAYEWREWVVRAIQLVDDRHLQGTASELI---YELQRFREDDLPPREE--------QKRRLTLVYEHLEKVMRSTELFAIPHELSAPELQRVWNELQNSIDRRFDVLERHRIQEGNSNDLLSRLARGIGITNEKLDLILKRIEDVEARVDTSPPAAVERTVSEIVDDLNALESPIARFFEDVEELKSMQHPEANDFYKQVYGLHQRRTTYLDRLTNQI--LVRLGVRTDSLHKENQQRLENMR---KTSFSRVEECIEWVRVRMEKLTTMEFLEDLETLEHVFEQHKFDNRDIQDFRQNVDEC-IARQAEVSAEDTYEYCELLRVLESEYQQLRDLSAGRMLDLDSLIAFVRAAQLELIWVSERESIEVTRNWSDIKQLDLPMLTNYYKQLLHEMELREKQYNDVHNQGAALLNQGHPAIRVIEVYLRQMQSQWDWLLALSKCLEEHLRDALNLKSFMEEASDAEAWIQEQSVRLENNYNR-TDFSLEEGERFLRELDEIKEILNKYHQVLMALTERCASISPLWQRGERI-PHP-IKVTALCDYSDENVTIKA-----GDDVYLLDNSDLIKWTIRDISGAEGQVPSVVFRIPPTDARLTALLNRLLQQFEKLKKLWDKKHRMVRFNMVLNTMRTIQGWDLDTFNSIDPDQRDAIMKALNDDANKLLSEL-----DPNDPLALRLREELRRTNEHFWNLL-------------NASQKPPEP---DWASQYDQKMAELLKKLEEAWRELNDAVGKPISRSPEDLERVIHAHKRFEDALQALDSDVANVKELFRQLPNPTPTQRVNHDRLNGLWDDLWDLSRMYVERIKVLESVLNGMVEVADIVRQHEITL-NSFDDLPAALDKLRGHHSQLL----EINMV---LKQQQTVIDQLNRNVALLRQHVSRTRINEGHHPDVDAIEDEVQKLNVRWENVNSQIASRLLAVESALQIQMVYRSEYETEMSWLDTVEETI-NRLRKPEELRPEQYQQQLDMLIAEYTNLQ----EHTQAIEHVNKEGGRFIHEAKIFDAKLGQYSDGIVGIHGPGIKSEFRRTK 1432
BLAST of Dystonin vs. Ensembl Celegans
Match: vab-10 (VAB-10B protein [Source:UniProtKB/TrEMBL;Acc:G5EFM4]) HSP 1 Score: 443.351 bits (1139), Expect = 1.608e-123 Identity = 509/2233 (22.79%), Postives = 1005/2233 (45.01%), Query Frame = 3 Query: 12957 QKVDPLKKQLE---ELIDIGNKACSTVISGLGFKHMEQEMDS----VKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLIN-TKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSP-TVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVD--PYQTRDIWEESLNLVKE----VKSHEETLKNLDQVGEDLKQISSENDSAAI-NCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNME---ILENETN-----SVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQ--APGSDL-KSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQN-KINNLDPD----QLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNI--DRQQSLITKLEEMRM------KLDEWFKEVNNRLFILGPLPTETRPVLTQI-QKTKEL---KNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMI--RADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRF----MDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWL-RAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQ-YNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF------KFKPAT-LPIPTKK---------PTTAKIPSPRVSQPLSSPRIH---QPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTP----KVVASPGLQRKSRIPT 19421 +KV LK+ L+ E +D N C +I G + +E+DS V ++ ++ VSD E VD + ++ K + + L ++E ++ ++PS + +K+QL+ + +L+ ++ ++ S+D ++ + + +K L N+ ++ +Y++LLN A + + AV L++ ++ P WL +A+K L P TV+ + E+ I E + LQ++ ++ LK ++ ++ + + VS++ N I+ ++ ++ + + + L + + F ++KL +D P + D+ E++ N++ E + +E + N+ +VG+ L I E + A I K++ L + ++ SA +K++L +IP++E F + D V+ L + R+ ++ + E E +LE + + SV++L + N L L S D ++++ + K V + V ++A +I +++ ++L +E S ++I E + + S+L+ +I TN ++ N K + ++KK+ RQ G++ + + VD K+ E + + L+ A+ L ++ S ++ L WL + + + + + P ++H +E+ + ++ +P+++ L +++ Q + + + + Y ++E ++ R +++++ E+++ L+ DR+ ++ S P L+ L I+ L Q D L ++ A++ S D+ + K N LEKL K ++ + ++ + ++L A FW++L + ++ L + + D+++++ + E++ I +S GKQL + V PD E+A ++ VR IT + ++++ LI +EE +L +W +L + P+ E +T+I Q KEL K+++ + E + QL + P++ V +A +N W+RL L +R+H+L+ ++L +G+ + + W+ T +L +I +N ++ +AQ K++ D++ Q SV+ + R A + I+ +L E + L+ + WE++++ + F++E A KEA G+ ++ + ++E S L K +GGLP+TA+ QL F +D+ L + + E + + + K + KW+ VK L R+ +L+ A E + +W+ E+ L Q +SR+ I +Q+ H + ++ + M H++Y +K D + I+N + S+ HR EK+ R++ER++ L E ++D L I+ L + + + + K++ ++ + KE ++ +D TR+ G L ++A + K+I + KW + K +R + A+L G ++++M +L SW+ +E + D++ V+ L++E S + + +++ ++ + A ALM ++ I L WN V + A + ++EA+ A EF+ ++L ++ + E +L+ + +E E + M G + + L + G EIL P AE +++++ +++++W ++ ++R L + + E+ A + EL+ + + Q + E+ I D + + +++ P + +K+ N P L ++WK++W + + L + L+E++ ++ + +EDW+ RY+ W +H+K+RV D FRR D H G V R+ FIDGII SKF T+R+EM VAD FDK G I+ ++F+ ALR D KP + E I E++ Q C+C PY+I + + Y+FGDT R+VRILRS VMVR+GGGW +LDEFL KHDPCR AKGR N + + + P +++M F K P T P P K P + + + H +P PR P +++ R+S+ S S+ TP +S R++RIP+ Sbjct: 2816 EKVRQLKESLKPVGEKMDAFNTDCKLLIKTAGPESDTKELDSLLKKVGDAYSDVVGKVSDKEMSVDAAVQQQGKVEDAYRALLNWLEETEEMMENRKKPSADAKVAKAQLHDYEVLMKHVEDKKPSVDGFKAMIEKIVAEASSDEEKKALGNKNAQIEDRYKDLLNSAVDRQRKLLDAVDLAERLQEVTIPLDSWLQSADKRLQALAKVPITVE--KAEEMIGEQEALQDE---LEHKSDDLKDVL-EIAPMLASLVSVEDANSISGQVNQLEARARALDAGITNMRPLLESFLQQIQDFTLDAEDMTQF-VGETEVKLGELDELPIEPDDLVEQT-NILAEIAVSIADRDEMMANIFEVGKQLA-IQGEPEEALIAQKKLDDLKFRYADLMTSADEKIALLAKAIPLSEGF---HEGFDTVMQVLEDMDRDLQTIDEEDPETQAELIFLLEEDISQKMRPSVDELTALS-NQLQVLCSAD----KADELQTNTIAMNKLVNSVADRVARRAERIEMASKQSRAVLDDLQYLIEWFSAARERILEGAPPSLDLEVLKSQLKHQRI--TNEEASAN--KVQFRNVAGEAKKVARQLGMEGNEANEKISDTVDEGKELVEEVMALCADRTETLERALALMEQLTSQFDELNKWLDQMDAELQASPSVTTATPAAELREMHDHNEELARMVAAY---RPIIEGFKSDVGSLHEVLAEDQAPLLESVAGELVQGYEEVREAVRARGHAIDNMMGATIGFGERLETLVANLQGAADRLRENEGISADPSVLESRLAENRSIVESLRDKQNAYDAL----------KQTASELLASAPEGDAAAGDVENKLNRLEKLW------KEIEREAVDRGVLLEDVLDKAKHFWSELDSCQKAVDDLRNRLELVEPATGHPEQLADQQEIMAQVASEMERARPRIEALSIAGKQLADYV------PDDEKA--VIENQVANVRGGF-STITGLFAEKKRDLIAAMEEAMTFHGDLQELLKWLDMAEQKLLKMSPV--EHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQLAADAPPHLAATVRQPVADLNTRWSRLNAALAEREHKLENLMLQMGKLASTIAQLTAWMDKTRATLKDIAPPKNAVNLRDIEIAQCKLVVLSNDIHAHQDSVNAVNRAAQKYIQTS-GALDAETSDSLKSMNLKWEDIQKVLESLAFDMEVAKKEAENVGGEVEKWQRWLEETESALLSTKPTGGLPETAEFQLDEFKALKLDVEHNASPLEAHLHATEQHLKEEPQDADTWLSKT----HGAMKTKWNKVKELLVDREKKLQVAYEQAVALESALNDMEDWIIAAERKLTDQPSISRLPDVIEKQLAEHESWMEEVAGRKMAMTKHQASGVHMQYYCEKKDAIPIKNRLVSLKHRVEKISGRTAERAKQLAVTRDEVATWQDGLHDLEHFISDVLVKIAPEPNTTSSLEKLKAKLEEVKEAQRDVTAKQTLFDVTRKRGIGLAERATRSEYKQISMTNEKMSKKWAEMLKKLRDRLREAEQAVLEGGAFEESMNDLESWVDDELERYQKAEHEPVFADIDGVRALVDEESRRSAERKTKENGVKTVVKKADALMASGVDEKDSIAQAKERLVEKWNQVEEAARHRGNSIKEAEQAAEEFDAKTHALLDWLAVEEQKLKASGL---DEVEGVKQEMDEAKGRYQECL-----------KKGEEILSKCQPAAEPILRNWMRVVEARWKEVSEKVDEREFTLLEQEQKAKEQN--------EQIEKLAKFAAQKREELNRMIEQPPAQDLDTMEQNICDFA-------NLDSELREQQPEVDAACKSAKKGARN-------------PAAEMLSTEWKKLWLDAMGLQSSLDNQKALLEEMKRLEGWKWEDWKERYVEWNDHAKARVNDLFRRIDRLHTGNVPRQVFIDGIIGSKFPTSRLEMAKVADRFDK-GDGMINAKEFINALRFDASNRNAKPQTDTEKITHEIELQKKTCSCCTPYQIEKISENHYRFGDTHIKRMVRILRSTVMVRVGGGWESLDEFLHKHDPCR----------------------AKGRLNINMFPE-ARPIHALDSMRSFTKNRHGKQLPTTGTPGPIMKIREKTDRSVPMSGGLGGTAGYTVTTDSHRHTDARPSRIPRAPSDMSAGRLSRVGSVSNSKNSIVDSSTPSRPESRASSDAGDRQTRIPS 4926 HSP 2 Score: 171.4 bits (433), Expect = 1.942e-41 Identity = 184/812 (22.66%), Postives = 366/812 (45.07%), Query Frame = 3 Query: 1803 YSSLNKWKNWIDEKCAIISEINFTNDLDGLNKIYEKFSTTFNEIKD---SVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICS-SKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANIDENE--INKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKDVPTNLDQLISAVTTSRQNQK-----DVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFE---SKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYEDIFKNYQNEIQNQIGGSNQDYFGYTK 4196 +S + + W+ + ++ + F DL+ L ++E+ +I+D +VDE + ++E + ++ + L++++ +L + D S + F+ + + W+ +E ++ W D + + L +K L+ E+E+RE N+ G L H A I+ L ++S+W W+L L+ CL+ HL + F EA++A+ I E + +L + + R L+EGE RE+ ++ E + Y + + + S+S L R I P + V A+C S EN G+ + L +NS W + + P++ F I + + L F LK LW K+ +R ++L+TM ++ W + F +++P R I++ LN DAN+L+ +L D N+ + L + N F L N S P + + + D ++ +L+ + +EL+ + P+ + LE + HK FE L+ + V ++ + + T +V +R+ LW+ LW+ + M+V ++K E + + E+ ++ + E+TL N + PA +D+++ +QL I+ V LK T +DQL V RQ+ + + D+ ++ E++ + R+E + +QI RL V + ++E + +W+ ++ T+ +++ P + + ++ L+ + N Q ++ I+ +NK F++ + ++ Y + I G + F TK Sbjct: 551 FSRVEECIEWVRVRMEKLTTMEFLEDLETLEHVFEQHKFDNRDIQDFRQNVDEC-IARQAEVSAEDTYEYCELLRVLESEYQQLRDLSAGRMLDLDSLIAFVRAAQLELIWVSERESIEVTRNWSDIKQLDLPMLTNYYKQLLHEMELREKQYNDVHNQGAALLNQGHPAIRVIEVYLRQMQSQWDWLLALSKCLEEHLRDALNLKSFMEEASDAEAWIQEQSVRLENNYNR-TDFSLEEGERFLRELDEIKEILNKYHQVLMALTERCASISPLWQRGERI-PHP-IKVTALCDYSDENVTIKA-----GDDVYLLDNSDLIKWTIRDISGAEGQVPSVVFRIPPTDARLTALLNRLLQQFEKLKKLWDKKHRMVRFNMVLNTMRTIQGWDLDTFNSIDPDQRDAIMKALNDDANKLLSEL-----DPNDPLALRLREELRRTNEHFWNLL-------------NASQKPPEP---DWASQYDQKMAELLKKLEEAWRELNDAVGKPISRSPEDLERVIHAHKRFEDALQALDSDVANVKELFRQLPNPTPTQRVNHDRLNGLWDDLWDLSRMYVERIKVLESVLNGMVEVADIVRQHEITL-NSFDDLPAALDKLRGHHSQLL----EINMV---LKQQQTVIDQLNRNVALLRQHVSRTRINEGHHPDVDAIEDEVQKLNVRWENVNSQIASRLLAVESALQIQMVYRSEYETEMSWLDTVEETI-NRLRKPEELRPEQYQQQLDMLIAEYTNLQ----EHTQAIEHVNKEGGRFIHEAKIFDAKLGQYSDGIVGIHGPGIKSEFRRTK 1319 HSP 3 Score: 101.679 bits (252), Expect = 2.498e-20 Identity = 62/192 (32.29%), Postives = 104/192 (54.17%), Query Frame = 3 Query: 732 KDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQ--QNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKIYQFRNQYADLYANLNSALEELNDDFDHNDFRIDFNQTRLENNYLTYLKQYESFCHLFDDISKVD 1301 +D V SD S + LLQW+R+ YP +N+ NFS+SW+DG AF A++H+ R ID IS +S + L AF A +E GV ++++ EDV + DEKS++TYV+SL+ P E ++ R DL + L + N+ D RI+ + R++ + +++ + + DD++ ++ Sbjct: 295 RDDVSLHGSDATSARDALLQWARRVTAGYPRVNVNNFSSSWRDGLAFNAILHRYRSSAIDWNKISSDSVSNTERLNNAFAAADREFGVERLLDAEDVDTNNPDEKSIITYVSSLYNALPHEPEMS------RGNSNDLLSRLARGIGITNEKLDLILKRIEDVEARVDTSPPAAVER--TVSEIVDDLNALE 478
BLAST of Dystonin vs. Ensembl Fly
Match: shot (gene:FBgn0013733 transcript:FBtr0087621) HSP 1 Score: 851.277 bits (2198), Expect = 0.000e+0 Identity = 655/2514 (26.05%), Postives = 1245/2514 (49.52%), Query Frame = 3 Query: 12297 KLESEIKTTQSDMHLIKPDMENTKLL---IASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAE-----------QKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANND-----PELAKL--LNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEES---LNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALV-----RENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTIND-----------SKKLIRQAPGSD-LKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ-RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTF----PKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILER---DTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPL---------IPIFDRSKRMETNQGI-----SKI-------------------------QEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIH-------QPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVA---------------------------SPGLQRKSRIP-TRQTSQQGSQASTRHQS 19469 KL +K + ++ + +++ K L I++ A+ + +A L E++ + +R L L + L S A+ + +++ +L +I+ ++ ++ QI D+ ++ + + + L + + + L + ++I T K++ ++DN + D +++L K + EF ++ + I + +++ P ++L + ++ F E+KV+PL ++++ G + SG+ +E++++ + ++ L + +++ + +D+ L++ KF +L L +++ + + ++ PS +Y K+QL + L L RQ+S+ L G ++ + + +++ ++ +L++L +++ L + AE + + A++++K F D P +WLD E+++ + PT D ++++RI+E+ L ++ L + ++ + S+ +++ K+ + +R++ + + + V ++D + ES +LK P + E+ L L + + H +++ + G +L + S +++ + K++ L + +++ L +N++P+ ++F A+N+L + S A + R+ D L + +M + + N V +CQ + E + +E I + +RF ++ ++ +KA ++ + +AK ++D+ +E + + E D +E L+ A ++ SIN I+ SKK++R++P S+ +L+ +D +K+ ++ + + L++A+PL++ F S+ L WL + E+ + + + L PDQ+ + + + L S + KPLLD + K+G L +V G I ++ RY ++ ++ R LE + +++ ++K++ L N D++ S P+K+ E++ D ++ DLDK Q +Q + K N D +V + KL K+++ +Q+ T + + ++LS+A FW L + ++ L+ + + ++ ++++R EID + ++ ++ + G L+ P++ P+V++ E+L ++ + + ++ N+ + E L ++ + ++ LG + ++ V QI++ K K++++P ++E +N+ +LT+ + P + L+ +N W LL G+ +RQ QL+ LL LG+F A++E + WI T+++L +K GD LE+ LA+ K++ D+ Q SV + ++I+ + S+ TQ +L +L W++L + A + ELE+AL+EA + + Q+I + ++ + + K GGLP+TA EQL+RFM++Y PK+ + E ++ S ++ + L ++WD V + A +K +LE A++ FH + F+ WLT EK L+ PVSR++ TI Q+E H+ L++D+++HRE ML LDK THLKY SQK D++LI+NL+ S+ HRWE+VVS+++ER+R LD+GYKEA+ F D ++ + ++L++ + + + P KI++ I K KE H LG YD T R G L ++AP D +D+++ L+ +W + +KSI+R++ L +ALLLSG + DA+ LL WL+ + +L+++ GD+ TVQ L H +E+ L+ R ++ + L + ++ + QL E++S W V ++ RL+ A A + +L ++ +EH+LR +P++EK + M+ H F K+L + E + + ++ +I+ AYP+A IK++++II+ +W ++ W+ R L+ HL L + +++LL WL+ EGTLL + +L + + +H+ F+ + +Q + D ++ PP P+F S+ +QG+ S+I E F +P+ L +KW+ VW + R++ L DH+ YLK+VE +NF+++DWR+R++ +MNH KSR+ D FR+ D D++G + R FIDGI+++KF T+ +EM+ VAD+FD+ G ID+++F+AALRPD + + KPAN+++ IHDEVK+ + CTC +++ Q G+GKY+FGD++KLRLVRILRS VMVR+GGGW ALDEFL K+DPCR AKGRTN ELRE+ G +MA F + +T P A S SSP H P S + P R ++IP SR S+S S TP ++ +PG R P +R S+QGS+ +RH S Sbjct: 6259 KLLERVKAIREELTNLSKPLQSLKALAKDISAEARAAGGDADHLTSEVDGLADRMSELQGRLDDRCGELQSAATAVSQFNEQMKSLGIDLNDLETEIEKLSPPGREIKIVQVQIDDVGKIQTKLDRLVGRLEDAERAADVLVDAGFAADTTQTREQISTLRKTLGRLDN----------RVRDHEDNLHSTLKALREFYDHQSQTLDDIQDVSDEFKRMKPVGSELDQIRRQQEDFRNFRERKVEPLAINVDKVNVAGRDLVRSAGSGVSTTAIEKDLEKLNDRWNDLKERMNERDRRLDVALLQSGKFQEALAGLSKWLSDTEEMVANQKPPSSDYKVVKAQLQEQKFLKKMLLDRQNSMGSLANLGKEVANHCEPGERASIEKQLNDLMKRFDALTDGAEQRELDLEEAMEVAKRFHDKISPLELWLDNTERSVKAMELIPT-DEEKIQQRIREHDRLHDEILGKKPDFSDLADVTAQLMHLVSDEEAVNLGEKVRGVTERYTGLVDA---SDNIGALLAESRQGLRHLVLSYQDLVAWMESMEAELKRFKSVPVYAEKLLEQMDHLLELNENIAGHASNVESTVESGAELMKHISNDEAIQLKDKLDSLQRRYGDLTNRGGDLLKSAQNALPLVQQFHEAHNRLVEWMQSAEAALAPSEPRQADVLRLEGELADMRPILDSINQVGPQLCQ----------LSPGEGA-ATIESIVTRDNRRFDSIVEQIQRKAERLHLSNQRAKEVTGDIDELLEWFREMDTTLREA------DLPAME------PKLVRAQLQEHRSINDDISSQKGRVRDVTAASKKVLRESPQSENTATLREKLDDLKEIVDTVAQLCSERLGILEQALPLSEHFADSHQGLTAWLDDMEQQISRLSMPALRPDQITLQQDKNERLLQSIAEHKPLLDKLNKTGEALGALVADDDGAKINEILDTDNARYAALRLELRERQQALESALQESSQFSDKLEGMLRALANTVDQVNQLDPLSALPQKIREQIEDNDALMDDLDKRQDAFSAVQRAANDVIA--KAGNKADPAVR-------------DIKAKLEKLNNLWNDVQNATKKRGSSLDDILSVAEPFWKQLNSVMKTLKDLEETLSCQEPPAAQPQDIKKQQVALQEIRHEIDQTKPEVEQVRRHGSNLMNMCGEPDK-PEVKKHIEDLDNAWDNITALYAKREENLIDAMEKAMEFHETLQNLLKFLTKAEDKFAHLGAVGSDIDAVKRQIEQLKSFKDEVDPHMVEVEALNRQAVELTERTSPEQAASIREPLSVVNRRWEALLRGMVERQKQLEHALLHLGQFQHALNELLVWINKTDSTLDQLKPIPGDPQLLEVELAKLKVLANDIQAHQNSVDTLNDAGRQLIETEKGSVEASTTQEKLRKLNNEWKQLLQKASDRQHELEEALREAHGYIAEVQDILGWLGDVDAVIGASKPVGGLPETATEQLERFMEVYNELDENRPKVETIQAQGQEYIKRQNQMKVSS--SNLQHTLRTLKQRWDAVVSRASDKKIKLEIALKEATEFHDTLQAFVEWLTQAEKLLSNAEPVSRVLETIQAQMEEHKVLQKDVSTHREAMLLLDKKGTHLKYFSQKQDVILIKNLLVSVQHRWERVVSKAAERTRALDHGYKEAREFNDAWSGMMQYLQETEQVLDQIIEEATASKEPQKIKKYIGKLKETHRQLGAKQSVYDGTMRTGKNLLERAPKGDRPVLDKMLIELKEQWTRVWSKSIDRQRKLEEALLLSGQFSDALGELLDWLKKAKSRLNENGP-VHGDLETVQGLCEHHKHIEQDLQKRAAQMQGVLKTGRDL--ERSGNNPEVGRQLDEMQSIWEEVKSAVAKRGERLQVALVDAEKLNARVQALFDWLDHAEHKLRYAKNAPDDEK--VSREMMDIHMDFMKDLRVREREKTETFEYAEDIINKAYPDAIPIIKNWLSIIQQRWEEVRQWAINRESKLEQHLQSLKDLDDTIEELLAWLSGLEGTLLNLKHEQLPDEIPPVEKLIEDHKEFMENTARRQNEVDRAC--KPRQLPPGARKPSRSGKTPVFKGSR----DQGLNARKGSRITPTRDTPDRDRLPHYGPRFSPSTSGPELEFRSPRAKLLWTKWRDVWMLSWERQRLLNDHLLYLKDVERARNFSWDDWRKRFLKYMNHKKSRLTDLFRKMDKDNNGMIPRDVFIDGILNTKFDTSGLEMKAVADLFDRNGEGLIDWQEFIAALRPDWQ--ERKPANDSDKIHDEVKRLVMLCTCRQKFRVFQVGEGKYRFGDSQKLRLVRILRSTVMVRVGGGWVALDEFLQKNDPCR----------------------AKGRTNIELREQFILADGVSQSMAAFTPRRST-------PNAAATAS-------SSPHAHNGGSSNLPPYMSGQGPIIKVRERSVRSIPMSRPSRSSLSASTPDSLSDNEGSHGGPSGRYTPRKVTYTSTRTGLTPGGSRAGSKPNSRPLSRQGSKPPSRHGS 8668 HSP 2 Score: 320.472 bits (820), Expect = 3.313e-86 Identity = 271/1125 (24.09%), Postives = 525/1125 (46.67%), Query Frame = 3 Query: 726 QFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDI--------EEKIYQFRN---QYADLYANLNSALEELNDDF------------DHNDFRID-FNQTRLENNYLTYLKQYESFCHLFDDISKVDRNNENQRKFHTISTLWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDGYPADQHYRIIININGKIDKVKKKFEKLSPPTLSSGV--ISNRQYTPIH-------------SMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTF-----NEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANIDENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKDVPTNLDQLISAVTTSRQNQKDVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIG 3938 + DIV K D++S ++ LL+W+R++ YP + + +F++SW+DG AF AL+H+ RPDL+D + + ++ LE AF+ +KE GV ++++PEDV + DEKS++TY++SL+++ P+ I + +++++R+ Q+ + L+E + F D FR D + + E + L + Y+ F+ + +VD E + + I W + T +++ +IL E ++++R ++++ + E + K+ ++E +I + + + + + ++ E+ E I +M L YP + ++ K++K+ +++ +L ++ V +S +Y P+H S ++ N + L + W K + ++ +DL + +KI ++F T + K S DE + + Q N L+ + EL +K +D S FL +++ + W+ KE +I W D + + L ++NL+ ELE RE + G L H A+ I+ L L+ +W W+L LT CL+ HL+ Y QFF E +A+ + + LNS+F + GLD+GE L R ++D+ E + + ETV + +Q+V L+ R + ++ V+AIC+ K+ Q +GE + L +NSG WRV ++ + P C L+ +A A L F LW K+ L+LR+ ++ +T+ +VK W + F + P R I LN DA++L L + ++ ++ + +++ N F E + R + + S + E ++ +L+D M +EL + +P+ D+D LE + H ++E L EP++ L + +T LK L+ +++LW++L ++ + +LK E + L++ + VI E+E L +++ P+ + ++ + QL QD I+ + + DQL R D+++L ++ + R+ + NQ+ +R+ L++ ++ ++W+ G Sbjct: 210 EISDIV-VGKEDNVSAREALLRWARRSTARYPGVRVNDFTSSWRDGLAFSALVHRNRPDLLDWRKARNDRPRERLETAFHIVEKEYGVTRLLDPEDVDTNEPDEKSLITYISSLYDVFPEPPSIHPLFDMESQRRVHEYRDLAQQFIYWCREKTAYLQERS--FPPTLIEMKRLLSDLQRFRSDEVSARKREKSKLIQI--YKELERYFETVGEVD--VEAELRPDAIEKAWYRMNTALQDREVILQQEIERLERLQRLADKVQREIKHVDQKLTDLEGRIGEEGRRIERLHPVDAKSIVEALETEIRHLEEPIQDMNQDCHVLNEGRYPH------VSELHKKVNKLHQRWAQLRTNFHTNLVQKLSGLKY-PVHETTVTRQTRMVVESRQIDTNPHFRDLQEHIEWCQNKLKQLLAADYGSDLPSVKEELDRQQHEHKIIDQFHTKILNDERQQTKFSGDELAL-------------YQQRLNQLQKVYAELLSTSTKRLSDLDSLQHFLGQASAELQWLNEKEQVEITRDWADKQ-LDLPSVHRYYENLMSELEKREMHFATILDRGEALLNQQHPASKCIEAHLTALQQQWAWLLQLTLCLEVHLKHATEYHQFFGEIKDAEQWLAKRDEILNSKFSQS-DFGLDQGETLLRGMQDLREELNAFGETVATLQRRAQTVVPLNKRRQPV--NRQGPVQAICAYKQQGQL---QIEKGETVTLLDNSGRVKWRVRTAKGQEGPIPGACLLLPPPDQEAIDAAERLKRLFDRSVALWQKKHLRLRQNMIFATIRVVKGWDFDQFLAMGPEQRTAIRRALNDDADKL---LSEGDPNDPQLRRLRREMDEVNRLFDEF--------EKRARAEEESKQASRIFTEECLAIKSKLED-------MARELDQIILAPLPRDLDSLEHVLEIHSDYERRLHLLEPELKHLQETFRTIALKTPVLKKSLDNLMELWKELNTQSGLHKDRLKLLEASLAGLEDNEHVISELENELA-RHQDLPSTAEGLQQVFKQLNHMQDIITQQQPQMDKMNDAADQL------GRMGVPTKVLGDLKRLHSNVERLNTRWSAVCNQLGERMRSCETAIGLMKNLQSSVQVEESWVDG 1275 HSP 3 Score: 143.28 bits (360), Expect = 8.390e-33 Identity = 488/2350 (20.77%), Postives = 930/2350 (39.57%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEF---------------------------PF-------LVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLV---------TENGKIIVDKNKPSLSFLDA----FNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEIAINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEA------IDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSN--QILTMNEAEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDP-IRCEIRDNCGHIITL-----NDAIN--EDLFPE-----FVP------------TDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNVTVYMT-----------------------------DVQNS------VQNK---TLEI--------PNEEKFVDTKTTKTLESIKRNYFGDDQDSKLIQTVKDASIRQELPLSVATDERITAVNRK----PSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIINP-----NTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNY-----YYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIIT--LTNRSLYFENLNKRHDNYQIIS--VYDP--------RINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHGLLHTIMKT---------RQYMPL-SC---PFTNVHIRTIEEEMNFSIPQSLPENVLRVFSQKPNDNKNVEGLIITSTSVN----LDHEIQIKTDNN--KNQVDINQADAPNFAKNYIEMVKSEMEKLSVIEQK---LLKEVNVF-------------LNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRS-RLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISN-----VKSVEDLQKSLTDLKLLDN------EFAS----YNNDIRVLIGSKIKFIDK----INKLEEQRKKFSD-LVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQ-------KILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIK-NIGSLSLDPKYINEQERLIQTILAEISSRQPFLENV------LMNNAS------RNEPKLKELDDKIKQKLLVASNIEAK-VNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPL---SPTSITKQPTTAN--RQXXXXXXXXXXXXXXADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQ--DLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEE-------IQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKID 11486 ++ + AV+ +DPE+G +FD + + + + + G++ IS++ + K E PF L+ +N S+ E L R ++ + P ++I L +A++ G V ++ KI+ K + LD + I L+E+ + G P L+L+ + G+ D KF TI ++Q LK A K I N E+L +L E++I I +I +GY D I ++ P +S+ E ENR I + RKR D +Y D F +N ++E++ + I+ + S V N + + + A E GI+D G + +D + IL +EA I+ VK++ +E+ F DP SG ++ +A+ L+D + K+ + L + A+D G + + KL N +T FD GI+ N +S + AI+ D L P GR I L E++ + + +P + C + + TL N IN E +F E FVP + E L G+ + T P + + EA ++++ S V + T D+Q + V N+ +LE+ P KF D T + L+ I+ + G + + K+ +ELPL+ A + V++ P + + + L L T +T +T +S +L P + R+++LEEAI+ NI DP ++R + + +V+ GL+ + + ++ + + + YV + V ++ L D +TG T + GS A + N SL K + + S V DP +L+ EA + +++ + +N +T+++ TL +A + GL+ T ++ Y P C PF +H I F++ +++ ++ S D G+I+ T+ +D TD N KN +D+ +A E ++ EK ++ E+ LLK V ++E NQ ++ + + +E SQQ V T + +I + ++ D + LE + L++ ++ +N+R+ RLL RL KL+ +D S+ +++ED ++SL+DL L + EF S + D+R + + KF+D+ + L + R + L V +S+ +S QE++ + Q YK L+++ + + + L +Q++ + + E L+ +I+S + + L+ E++S+ +++ + +L N ++SL + E I+ PI N + + L E + +++ + + ++++L W+ + + + K N+ SL + + EQ R + +LA++ S Q +++V L+ +AS + E L ++ K +KL +N + ++D L + + + +A E L R L E+ +++E+ + E + K+L+S + D + ++ LE W ++N I+ R+K + Y LK +++ L + E ++ P+AIDL ++ QH++++ ++ P I++ IG++YD+++ + SP RK S T PL S + + PT S S SS D L+ E S ++++I +RY IG +L +R+ ++ L + + K + L+ +L V N + I+ R + + +L + T Q D+LR + VPG +L+ + D +++K+ +L D K + + G +K +++ KERML VLGP+ + +Q+QQV L +E + +K + +G +++ ++ T + +E L + K D+L L DR ++ SK+F +N + + L + + +D + T D +E ++ +L+ + +L + E + TL + D + ++ ++V+ L + +Q K+D Sbjct: 3827 ISLEAAVRKGLYDPETGKLFDSESQNQVDVQKSIEIGLVDPKISLIVDTVTKKEVKLDCAIEDDLVLPATGQIKDNKNNTLVPFDVGVQQCLLKTDNVTWSLPELLQREYYTPSTGKVLNPVTGEEILLQQAIEMGFVELETTLVKDVDHDKILPGKEAAKVGLLDTVRGTLSSPNISLDEAFVKGYLISTKKP-----LSLVDCLLRGLYDPSTAKF--TIDDKQLDLKAAIAQKLI-----------------NPEELVLLDPKTESIISITE------------AIAKGYLDPIEG--------YVINPYASTKLSLHEA-----------LENR-----------------ILIPPKRKRSL-----------PDAVYRGLYDPKTGQF---SNTVTREKLTTERAIRRGILDPDST--VVNVGSGQIIPFGVATETGIVDSKHGTVRDADDHPIDFKEAFDRGIL---VEAKKPLRLIEAVVKNVYDEVDG-HFVDPKSGEKLNFAEALNTNLLDEHSVQIRDFKTGLYKQLNLTHAKDTGII--DAQNSKLLYNNQTMTLKHA-FDIGILMDVNAPIS--IQRAIHQGLFDDKTGKLSDPRTGRQITLLESMRSFVVNPHLPCYFDEQTEQMYTLSETCRNGIINRREGVFREPGSNSFVPLGEALSLGLIVDIENAGFGLYELLSMGFYETSTRKVLHPVTNRKLNLNEACVEDVVSLSSSLVKHHETGKYLRLANAIKEQLVDDSRGCYNLGNEQLDLQAARARGLIVSNRRLLSLELVLRQQLYRPETGKFCDPTTGEYLDLIEAIHSGFIDPATTV--FKNQLTGKELPLTEAIENGDIDVSKGRVFDPKSKSAYNYDVALSRGILVT---ITRPLTDRNDVVRRQDSVELLNQTPVSVVISKPREMSLEEAIRYNIIDPKTALVRDFDSFKFLPYSVAVERGLV------DTTKRTLVDPKALYFAFDPTLIVYVREPVTFDQAAESKCL-------------DLQTG-LLTYVPASVPGSATAAPASDDSANDSLTVIETPKVYTLKEAASAGVVDPDSALVKDLAKAKLVRLPEAFRKGLMDANKANVLNTQTSKLCTLQEAYESGLICTPKRSFGLLEAITFNLYNPTNGCLVDPF-QMHPDIIRRR-KFTLAEAIGSGLVDPSSTVVRDPST--GVIVPLTAAISSGLIDATEGRLTDANEPKNNIDLVKAAEKGLLLPA-EQRQAVFEKFNMCEENVNDLLKWVTTVEQKISSVGGPREKIDELRNQ--INALKQIKDEIESQQRPVATCLEQIRQIVLTGGDVLSAPEVTTLENSGRELRSRVDR----VNDRTVRLL-----------RRLEAGRDELTKLRSELDVFSDWLQVARRTLEDKERSLSDLTRLPSQADSVREFVSDVIGHQADLRFITMAAQKFVDESKEFLAILNDFRTSLPERLPHVEPLSSAESPIRQEVS-----LVSAQ------YKDLLNRVNALQDRVSGLGGRQREYQDALDKANEWLRSVHPRVSRIISEPIAGDPKGVQDQMNEAKALHNELLSSGRLVDNAQQALDNLLRSLGGQLSPME-INQLELPIADLKNNYQQLLDNLGEHCKTLDKTLVQSQGVQDALDSLVGWVNQAEDKFKMNLRPASLIKERLQEQIREHKVLLADLQSHQASIDSVQVSAKHLLASASNARIAKKVESNLNDVTVKF-EKLYEKANKRGEFLDDVYNRLSRYLDEISTVEQRMASLQEALDSRETSLLSTEELARRMNELSRDKDQLAPQFEDCVRSGKDLISLRDVTDTGVLRDRIKALESQWRNINISIDERAKLSKQKAEQQLAYEGLKDQVLSWLASTEARVNGLPPVAIDLDRIKQQHDELKPICKDYRDYAPTIDKINDIGAQYDALI-----------RPESPARKRSTYSPIKRTSPLRRMSGDARSPSPTKGGILSPLSTGSSGFGSRRSSQDGFQLS-ELSPVQQQLSEINNRYGLIGVRLNDRQHELDNLNEELRKQYENLKGLAQFLERIQRQLPKESVSNKDEAERCIKQARKILEDMYEKQSLLDT-TKAQVKDILRRKSDVPGAEQLRQENDSIQEKWKNLNDICKNRIAFSEKLRDFLDTHGNLKSWLDS----KERMLTVLGPISSDPRMVQSQVQQVQVLREEFRTQQPQLKHFQELGHDVVDHLAGT-PDAQAVEIKLKDILGKWDDLVGKLDDRANSLGGAADSSKEFDAAVNRLREALQNISDNLD----TLPTDGDHQENLRKIENLERQLEGQRPLLADVEQSAATLCNILGDPASRADVNSRVAALEKQYLALQKKLD 5997 HSP 4 Score: 95.5153 bits (236), Expect = 2.075e-18 Identity = 341/1856 (18.37%), Postives = 760/1856 (40.95%), Query Frame = 3 Query: 12783 IIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSE--------QKVDPLKKQLEE----LIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDL--------DAEEEPSIEYHKS--KSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND---DSSIDESIKKLKIIINKVDGVFSENVSID---TKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFE---SAMKDLKLNIVDPY---QTRDIWEESLNLVKEVKSHEETLKNLD----QVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDI-----FVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNF----EQKINEMSDQINNDY-------SELEECKI---DFTNLLSAWNEQK-ESINSTIND----SKKLIRQA-PGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYD--LDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKL----AKISSSNKGLQSQTMEYKEKIMNLLSLANEF--WNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQR--LEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKR----FMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATH-LKYISQKHDIVL--IRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQ-SEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGS-IKHYINIIKSQWSDLLSWSEQRGLNLKDHL 18104 ++ +DDR NSL D ++ D A N L + L N S N+ +K++ L++QLE L D+ ++ +T+ + LG +++S + ++ Q ++ ++ +D K+ + + SL + + F EN S+ L + + + HK + Q+++H + + R+ + L G DL T + ++ +LD + ++E L A ++ R ++ K + E L WL TAE LA+ T + ++E R+++ + +++ S E+ K L F + ID K ++ + DR+ + + L ++ D++ + +L E +A L DP + + I EE NL K ++S + K++ G D ++SE D A +++ L D+ + +++ +F N ++ + L L E + L+ R ++I++ + + V K+ + LD+L V E++ E+ D+ F + + +E ++ + K +G + + E+NL ++ L F Q ++++ D +++++ SEL++ + DF N + E+K E + ++ + L+R A G +++ ++++ + + + + ++LD A+ + +F + L WL +TEE + K + D + QE K L D++ + + G ++ + +I + D KR++ + + + R DLE+ + + ++K+ L+N + EK+ + + D L+D L K F D + + + + +++V + + + ++ A ++ S +GL+ + Y++ + + S+ E + + + +K E HL +L E++ G H ++ + G +L++ ++N +E ++ + L+R + + + + + L+ + E +L EW + L P+E R L+ ++ ++ INQ+G QL + S + S + R N + +++ + ++ +L E +DE +EW + +L + + + L +H+ I D++ + V + + ++++E S + AT R L+ L++ + + + + LE AL + F Q ++ +D++ ++ PD Q + I P L+ + A ++ I + ++ D ++ ++ R+ LE A++ F + + L T +NQ P+S + I EQ+E + AL D+ ++ + + A + K D + I+ + +++ W V + + +R +LD A+ F +++ + E L P I++Q +E + + RR G L + D ++ + + +L W ++ +RE+ L DA+ + + + + NLL +L E K + G D++ V+ + + + ++ +E +N A+ L + S E ++ I + L+ + W + + E++++LE A +F+ N L + +K++ L Q P + +L+ ++ + ++ ++ ++ G +++ + E S + + + ++W LL + R L++ L Sbjct: 5886 LVGKLDDRANSL-----------GGAADSSKEFDAAVN--RLREALQNISDNLDTLPTDGDHQENLRKIENLERQLEGQRPLLADV-EQSAATLCNILGDPASRADVNSRVAALEK--QYLA-LQKKLD---TKKAETEASLRDGRHFAENCSKTLGWLGGELSNLTDRLLVSAHKPTLQHQIDTHEPIYREVMAREHEVIMLINKGKDL---TDRQQDRGVKRDLDRIQQQWEKLRREAVDRHTRLQTCMEHCKKYSQTSETFLAWLRTAEDKLADL-TPGVLSKAKLETRLRDLQTFRSEVWKHSGEFENTKGL-------GETFLSSCDIDKEPIKAELQDIRDRWERLNNDLIARAHEIENCSRRLDDFNDELRNLDHSLGRCEDRLAAHDALGGAAKDPKLLERVKAIREELTNLSKPLQSLKALAKDISAEARAAGGDADHLTSEVDGLA--DRMSELQGRLDD-------RCGELQSAATAVSQF---NEQMKSLGIDLNDLETEIEKLSPP--GREIKIVQVQIDDVGKI----QTKLDRL--VGRLEDA-ERAADVLVDAGFAADTTQTREQISTLRK---TLGRLDNRVRDHEDNLHSTLKALREFYDHQSQTLDDIQD-VSDEFKRMKPVGSELDQIRRQQEDFRN----FRERKVEPLAINVDKVNVAGRDLVRSAGSGVSTTAIEKDLEKLNDRWNDLKERMNERDRRLDVALLQSGKFQEALAGLSKWLSDTEEMVANQKPPSSDYKVVKAQLQEQKFLKKMLLDRQNSMGSLANLGKEVANHCEPGERASIEKQLNDLMKRFDALTDGAEQRELDLEEAMEVAKRFHDKISPLELWLDNTERSVKAMELIPTDEEKIQQRIREHDR-LHDEILGKKPDFSD-----LADVTAQLMHLVSDEEAVNLGEKVRGVTERYTGLVDASDNIGALLAESRQGLRHLVLSYQDLVAWMESMEAELKRFKSVPVYAEKLLEQMDHLL----------------ELNENIAG----HASNVESTVESGAELMKHISN-DEAIQLKDKLDSLQRRYGDLTNRGGDLLKSAQNALPLVQQFHEAHNRLVEWMQSAEAAL-----APSEPRQA-----DVLRLEGELADMRPILDSINQVGPQLCQLSPGEGAATIESIVTRDNRRFDSIVEQIQRKAERLHLSNQRAKEVTGDIDELLEWFREMDTTLREADLPAMEPKLVRAQLQEHRSINDDISSQKGRVRDVTAASKKVLRESPQS-ENTATLREKLDDLKEIVDTVAQLCSERLGILEQALPLSEHFADSHQGLTAWLDDMEQQISRLSMPALRPDQITLQQDKNERLLQSIAEHKPLLDKLNKTGEALGALVADDDGAKINEILDTDN----ARYAALRLELRERQQALESALQESSQFSDKLEGMLRALANTVDQVNQLDPLSALPQKIREQIEDNDALMDDLDKRQDAFSAVQRAANDVIAKAGNKADPAVRDIKAKLEKLNNLWNDVQNATKKRGSSLDDILSVAEPFWKQLNSVMKTLKDLEETLSCQEPPAAQPQDIKKQQVALQEIRHEIDQTKPEVEQVRRHGSNLMNMCGEPDKPEVKKHIEDLDNAWDNITALYAKREENLIDAMEKAMEFHETLQNLLKFLTKAEDKFAHLGA-VGSDIDAVKRQIEQLKSFKDEVDPHMVEVEALNRQAVELTERTSPEQAASIREPLSVVNRRWEALLRGMVERQKQLEHALLHLGQFQHALNELLVWINKTDSTLDQLKPIPGD--PQLLEVELAKLKVLANDIQAHQNSVDTLNDAGRQLIETEKGSVEASTTQEKLRKLNNEWKQLLQKASDRQHELEEAL 7636 HSP 5 Score: 83.1889 bits (204), Expect = 1.159e-14 Identity = 131/600 (21.83%), Postives = 232/600 (38.67%), Query Frame = 3 Query: 5595 IIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQ----------------------------------------------AINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRI---VFLTCPLIKFSISIDEIAINIDQTECNLFE------NRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNY-KIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDR-------KFENFWNTKSNQILTMNEA--EDL------GFVLTEKLEIKLPTINDLITQGLVD------FDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHI--------------ITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNVTV 7121 I P + LT+ AIQL I+D + + + + + + +L++A + I L K L + + +L++L+ AI +D KTG ++ + Q IS+ E Y + ++ I I + +D D+ + F N+ + ++ V D+K++ I+L EA + +N G Y +E + +F +A + I + + + +P+ +E +S QA+E G++D GN K I + + + EAI G + L E K ++D ++G +IS +A+E+GL+ + F + +SN ++ N A DL GF L + +P + +++GLV F GI +++ + + N ID L P G + L AIE P + + +I +T+ E P D +TF EA+ QG+ID + F+DP+ N+Y V++AL +L P SN TV Sbjct: 1501 IRDPRTGRVLTIGEAIQLRILDVRTGEML--VGDRRITLEQAADQGLIDLQLAKQLLEPGAGRDASGRELSLLEVIQREISEAESGYETAEKRIKVNNTVTVEQTSGELGSPENPRNIADAITAGSVDTKTG-LYRVKSGQTISLAEAYERGYLIRHESVTIKSNALCLSDAIAHGL-VDGAGWIADRNSGDKFRLDSAIANQLIDASVREVVDAKRDTKITLQEALQSGVLNAKTGRYVNEVTKEKLTFAEARNRQLIVK---------PYTLKDICDLNLLDKQAQITSPMRREKLSIMQAIEAGVLD---GNLLKCITKRKGEL-VTLQEAIADGIV---------LPAECK---YRDFMTGELISIPEAVERGLISSVAQRSIFDIDGFKDLRSNDYVSFNVALSRDLLRRKSTGFALETGRDSLVP-LEVAVSEGLVRQEVYEMFSRGIGVQNASGKELSVFDLVYHNLIDPKTGYLLDPKTGETVPLDTAIERKFITPEGALLLSSLLNITLTTETVTRTINRYVTIRAGSQE-------PVDSVLLTFTEAVRQGFIDEERQLFKDPKTGNIYSVQQALNYGLL-VPDSNQTV 2062 HSP 6 Score: 82.8037 bits (203), Expect = 1.703e-14 Identity = 191/947 (20.17%), Postives = 373/947 (39.39%), Query Frame = 3 Query: 5061 ITNTELKYTDAIRYQYINDDISEILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGIL-------SKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGY-------IKLNESLISGPNQEI----IHPNLTQKLTLLGAIQLGIIDTKNEKFINTITN--EQFSLKEAYENKFI----SKSLLKDLTVYC------GITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEG------------YYDK------IITENQYNRIV-----FLTCPLIKFSISIDE-----IAINIDQTECNLFE--NRKLYQTIT-TVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFI------------QTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLPTINDLI-TQGLVDF--DSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNVTVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQDSKLIQTVKDASIRQELPLS----VATDERITAVNRKPSN--SMENAHSLGL-KSPKLSTN--ESLTSNITSLTGSNTENNSTQLFIINPNT--GRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLI-VNEG 7637 I + +L AI + IN + E++ +DP S ++ EA+ + DP G + + + + LH A + IL S P ++ + + + F + EK + A+ RGI+D +S + Q I A + G+V + D + + F +AF++G ++L E+++ E+ + P +KL A+ ++D + + + T +Q +L A + I SK L + T+ GI N ++I +AI++ L D KTG++ D + I++ E Y+D+ ++E N I+ P + + E + ++I+ L+E + Y+T T V N ++L+EA D ++ + H + Y +AI + Q + + ++ R + + + ++ ++ P T ++ D +G Y + + EAI SG+I+ FK+ ++G + +AIE G +D ++ KS + A G ++T + L ND++ Q V+ + + + ++ M+L EAI N ID ++++ D+ + + A+E L D + + D + P + + +TF++A E +DL+T Y V ++ + P S+ + N +L + K K + + D DS L++ + A + + LP + + + +N + S +++ A+ GL +PK S E++T N+ + T + F ++P+ RK L EAI + DP ++R + ++ GLI EG Sbjct: 4041 IDDKQLDLKAAIAQKLINPE--ELVLLDPKTESI-ISITEAIAKGYLDPIEGYVINPYASTKLSLHEALENRILIPPKRKRSLPDAVYRGLYDPKTGQFSNTVTREKLTTERAIRRGILDPDSTV-VNVGSGQIIPFGVATETGIVDSKHGTVRDADDHPIDFKEAFDRGILVEAKKPLRLIEAVVKNVYDEVDGHFVDPKSGEKLNFAEALNTNLLDEHSVQIRDFKTGLYKQLNLTHAKDTGIIDAQNSKLLYNNQTMTLKHAFDIGILMDVNAPISIQRAIHQGLFDDKTGKLSDPRTGRQITLLESMRSFVVNPHLPCYFDEQTEQMYTLSETCRNGIINRREGVFREPGSNSFVPLGEALSLGLIVDIENAGFGLYELLSMGFYETSTRKVLHPVTNRKLNLNEACVEDVVSLSSSLVKHHETGKYLRLANAIKEQLVDDSRGCYNLGNEQLDLQAARARGLIVSNRRLLSLELVLRQQLYRPETGKFC-----------DPTTGEY-----------LDLIEAIHSGFIDP------------ATTVFKNQLTGKELPLTEAIENGDIDVSKGRVFDPKSKSAYNYDVALSRGILVT--ITRPLTDRNDVVRRQDSVELLNQTPVSVVISKPREMSLEEAIRYNIIDPKTALVRDFDSFKFLPYSVAVERGLVDTTKRTLVDPKALYFAFD--------PTLIVYVREPVTFDQAAESKCLDLQTGLL-------TY-VPASVPGSATAAPASDDSA----------NDSLTVIETPKVYTLKEAASAGVV-------DPDSALVKDLAKAKLVR-LPEAFRKGLMDANKANVLNTQTSKLCTLQEAYESGLICTPKRSFGLLEAITFNLYNPTNGCLVDP----FQMHPDIIRRRKFTLAEAIGSGLVDPSSTVVRDPSTGVIVPLTAAISSGLIDATEG 4909 HSP 7 Score: 80.1073 bits (196), Expect = 9.771e-14 Identity = 144/665 (21.65%), Postives = 256/665 (38.50%), Query Frame = 3 Query: 5034 DKQIKFLDPITNTELKYTDAIRYQYINDDISEILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVT---------ENGKIIVDKNKPSLSFLDAFNKGYIKLNESL--ISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEIAINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPI----TKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKII------GFKDPISGGIISP----------------IDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPN-------REVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD 6896 DK K DP T ++ +++R +N + F + +E + L+ E +N + G + +S++PL A G++ VDI N + E L G + ++ + P ++K++L EA +V+ E GK + N +D Y NE L + + +I N + L+L ++ + + KF + T E L EA + FI + TV+ G ++L + +AI ID+ G++FD + + YD ++ +V +T PL +++ D E L QT +V SK E +SL+EA + + I+ + + ++ A++ + T + ++ F+P +E V+ QA E +D +G + +P A + G A S N+ L +I K+ S G++ P +A KGL+D N NT+++++ T+ EA + G + T K L + IT L + +G + P R TL EAI S +D ++++ P G + L AI + L D + D Sbjct: 4327 DKTGKLSDPRTGRQITLLESMRSFVVNPHLP-CYFDEQTEQMYTLS--ETCRNGIINRREGVFREPGSNSFVPLGEALSLGLI-------------------VDIENAGFGLYELLSMGFYETSTRKVLHPVTNRKLNLNEACVEDVVSLSSSLVKHHETGKYLRLANAIKEQLVDDSRGCYNLGNEQLDLQAARARGLIVSN-RRLLSLELVLRQQLYRPETGKFCDPTTGEYLDLIEAIHSGFIDPAT----TVFKNQLTG--KELPLTEAIENGDIDVSKGRVFDPKSKSAYN-----YDVALSRGI---LVTITRPLTDR----NDVVRRQDSVEL-------LNQTPVSVVISKPRE-MSLEEAIRYNIIDPKTALVRDFDSFKFLPYSVAVERGLVDTTKR--------------TLVDPKALYFAFDPTLIVYVREPVTFDQAAESKCLDLQTG---------LLTYVP---ASVPGSATAAPASDDSANDSLTVIETPKVYTLKEAASAGVVDPDSALVKDLAKAKLVRLPEAFRKGLMDANKANVLNTQTSKLCTLQEAYESGLICTPKRSFGL---LEAITFNLYNPTNGCLVDPFQMHPDIIRRRKFTLAEAIGSGLVDPSSTVVRDPSTGVIVPLTAAISSGLIDATEGRLTD 4913 HSP 8 Score: 73.559 bits (179), Expect = 1.118e-11 Identity = 67/262 (25.57%), Postives = 121/262 (46.18%), Query Frame = 3 Query: 5364 SISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSL-LKD------LTVYCGITNG-NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEIAINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFI 6125 S++EA RG + + +IK N + L +A+ +GLV G I D+N LD+ + LI +E++ K+TL A+Q G+++ K +++N +T E+ + EA + I K LKD L IT+ EKL+I+QAI ++D + + + +++ E D I+ + F+T LI +++ I+ + ++F+ I D + N+Y+S + A RD + Sbjct: 1641 SLAEAYERGYLIRHESVTIKSN---ALCLSDAIAHGLVDGAG-WIADRNSGDKFRLDS------AIANQLIDASVREVVDAKRDTKITLQEALQSGVLNAKTGRYVNEVTKEKLTFAEARNRQLIVKPYTLKDICDLNLLDKQAQITSPMRREKLSIMQAIEAGVLDGNLLKCITKRKGELVTLQEAIADGIVLPAECKYRDFMTGELISIPEAVERGLIS-SVAQRSIFD-------IDGFKDLRSNDYVSFNVALSRDLL 1884 HSP 9 Score: 71.2478 bits (173), Expect = 5.522e-11 Identity = 142/663 (21.42%), Postives = 269/663 (40.57%), Query Frame = 3 Query: 6399 FVIDIPINEAILS-GYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGH-IITLNDAINEDL---------FPEFV--------------PTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILD--------------------------HPQSNVTVYMTDVQN------SVQNKTLEI----------PNEEKFVDTKTTKTL---ESIKRNYFGDDQDSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLS------TNESLTSNITSLTGSNTENNSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTG--KSTTLINGLENGSVFATIITLTNRSLYFEN--LNKRH--------DNYQIISVY----------------DPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHGLLH 8075 ID + +L G + +I E + S +++ I +DP+SG +I AIE G+VD + + ++ + + M A LGF++ K ++ + +GL D ++G + + + + ++I +D S++ + + L AIE+DL P +I+DN + ++ + + + L PE + P +I ++A+E G+++L+T +D +D + +EA +LD P S V + + + ++ +K L++ P E +D KT + E+I + Y D + +I AS + L L A + RI + K S+ +A GL PK T E LT+ G + +ST ++N +G+ + A + I D +R +++ ++E+ G++V RL E +++ + ++V G + L N +D + I+D KTG K L + + G II N L + N + +H D IS+ DPR + IT E++ V+N Y + +T ++ TLS+ ++G+++ Sbjct: 3737 VTIDTQTGQVVLDDGRVCSIVEAINSGKLDIQSISVRDPVSGEVIPLRMAIELGVVDMQAGTVIDIQTLKEIPMELAFQLGFLVPGAR--KPISLEAAVRKGLYDPETGKLFDSESQNQVDVQKSIEIGLVDPKISLIVDTVTKKEVKLDCAIEDDLVLPATGQIKDNKNNTLVPFDVGVQQCLLKTDNVTWSLPELLQREYYTPSTGKVLNPVTGEEILLQQAIEMGFVELETTLVKDVDHDKILPGKEAAKVGLLDTVRGTLSSPNISLDEAFVKGYLISTKKPLSLVDCLLRGLYDPSTAKFTIDDKQLDLKAAIAQKLINPEELVLLDPKTESIISITEAIAKGYL-DPIEGYVINPY--ASTK--LSLHEALENRIL-IPPKRKRSLPDAVYRGLYDPKTGQFSNTVTREKLTTERAIRRGI-LDPDST---VVNVGSGQIIPFGVATETGIVDSKHGTVRDA-DDHPIDFKEAFDRGILVEAKKPLRLIEAVVKNVYDEVDGHFVDPKSGEKLNFA-EALNTNLLDEHSVQIRDFKTGLYKQLNLTHAKDTG-----IIDAQNSKLLYNNQTMTLKHAFDIGILMDVNAPISIQRAIHQGLFDDKTGKLSDPRTGRQITLLESMRSFVVNPHLPCYFDEQTEQMYTLSETCRNGIIN 4380 HSP 10 Score: 55.4546 bits (132), Expect = 2.922e-6 Identity = 81/378 (21.43%), Postives = 147/378 (38.89%), Query Frame = 3 Query: 5349 NNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKL-NESLISGPN-----QEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSL-----------------KEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEIAIN--IDQTECNLFENRKLY------QTITTVYDS----KQNEYISLDEARKRDFIN-DDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXX------XXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGII 6356 E +I +A +G++D + P Q IS+ EA+ + I+D + + A G + + L++ + + P +++ + A + GI+ + +E ++ K+A I + + L TN E + I +A+N LID + GQ+ D NN+ +++ + KII Q N I+ PL K S+S+ +A ID + Y + V D + E +L+EA + IN DD Y K + T+AI+A + ++ K +V + + S V +P TK+ + +QA+E+ I Sbjct: 2315 TGETENIFDAARQGLVDEQLIKIVDPTTKQPISVTEAIARSIYDPKTATILDSEGQPVDLITATKLGLLSVVGAPLVAAEGALRTVRFVTDPRTGEQIPVEVAYERGIVSRDQLHRGRSFDSEPATVEDKVVVLQRMRKVILKPKDALRKGIIDEETCEILENTSNFTNPKGEVVNITEALNTGLIDGRRGQVIDPQNNRVLNLRQAVEQKIIDSEQTNHILM---PLAK-SLSVPRLADQGLIDPQTQTIVHPESGYPLSIHEAIVCEVLDPHSKLHKPEKCTLEEAITKGIINADDSTFNYKNK---TLNITEAIEAKLFDPSYDQQKSKVEIPPVGMIFPVAVEKSLVEPSKRVVLHPSTKKALPIKQAIEENFI 2685 HSP 11 Score: 54.299 bits (129), Expect = 7.147e-6 Identity = 68/282 (24.11%), Postives = 124/282 (43.97%), Query Frame = 3 Query: 6294 VFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGF-KDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIV-------TLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV 7115 + +P TK+ +S +A+ I D + I++ G +D+ I L G + + + + L+ + F DP +G I A E+G+V R + + ++ T+ ED VL ++ L D + +G++D ++ + T P EV + + EA+N+ ID R + P N R + LR+A+E + D + HI+ +P K+ ++ +QG ID +T T P + + EA+ +LD P S + Sbjct: 2337 IVDPTTKQPISVTEAIARSIYDPKTAT--ILDSEGQPVDL-ITATKL-GLLSVVGAPLVAAEGALRTVRFVTDPRTGEQIPVEVAYERGIVSRDQLHRGRSFDSEPATV---EDKVVVLQRMRKVILKP-KDALRKGIIDEETCEILENTSNFTNPKGEV-VNITEALNTGLIDGRRGQVIDPQNNRVLNLRQAVEQKIID------SEQTNHIL--------------MPLAKS-LSVPRLADQGLIDPQTQTIVHPESGYPLSIHEAIVCEVLD-PHSKL 2587
BLAST of Dystonin vs. Ensembl Fly
Match: shot (gene:FBgn0013733 transcript:FBtr0273222) HSP 1 Score: 849.736 bits (2194), Expect = 0.000e+0 Identity = 654/2496 (26.20%), Postives = 1245/2496 (49.88%), Query Frame = 3 Query: 12297 KLESEIKTTQSDMHLIKPDMENTKLL---IASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAE-----------QKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANND-----PELAKL--LNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEES---LNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALV-----RENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTIND-----------SKKLIRQAPGSD-LKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ-RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTF----PKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILER---DTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHD------EIITNSKK-----KTPPLI------PIFDR----SKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQ-------PVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVA---------------------------SPGLQRKSRIP-TRQTSQQGSQASTRHQS 19469 KL +K + ++ + +++ K L I++ A+ + +A L E++ + +R L L + L S A+ + +++ +L +I+ ++ ++ QI D+ ++ + + + L + + + L + ++I T K++ ++DN + D +++L K + EF ++ + I + +++ P ++L + ++ F E+KV+PL ++++ G + SG+ +E++++ + ++ L + +++ + +D+ L++ KF +L L +++ + + ++ PS +Y K+QL + L L RQ+S+ L G ++ + + +++ ++ +L++L +++ L + AE + + A++++K F D P +WLD E+++ + PT D ++++RI+E+ L ++ L + ++ + S+ +++ K+ + +R++ + + + V ++D + ES +LK P + E+ L L + + H +++ + G +L + S +++ + K++ L + +++ L +N++P+ ++F A+N+L + S A + R+ D L + +M + + N V +CQ + E + +E I + +RF ++ ++ +KA ++ + +AK ++D+ +E + + E D +E L+ A ++ SIN I+ SKK++R++P S+ +L+ +D +K+ ++ + + L++A+PL++ F S+ L WL + E+ + + + L PDQ+ + + + L S + KPLLD + K+G L +V G I ++ RY ++ ++ R LE + +++ ++K++ L N D++ S P+K+ E++ D ++ DLDK Q +Q + K N D +V + KL K+++ +Q+ T + + ++LS+A FW L + ++ L+ + + ++ ++++R EID + ++ ++ + G L+ P++ P+V++ E+L ++ + + ++ N+ + E L ++ + ++ LG + ++ V QI++ K K++++P ++E +N+ +LT+ + P + L+ +N W LL G+ +RQ QL+ LL LG+F A++E + WI T+++L +K GD LE+ LA+ K++ D+ Q SV + ++I+ + S+ TQ +L +L W++L + A + ELE+AL+EA + + Q+I + ++ + + K GGLP+TA EQL+RFM++Y PK+ + E ++ S ++ + L ++WD V + A +K +LE A++ FH + F+ WLT EK L+ PVSR++ TI Q+E H+ L++D+++HRE ML LDK THLKY SQK D++LI+NL+ S+ HRWE+VVS+++ER+R LD+GYKEA+ F D ++ + ++L++ + + + P KI++ I K KE H LG YD T R G L ++AP D +D+++ L+ +W + +KSI+R++ L +ALLLSG + DA+ LL WL+ + +L+++ GD+ TVQ L H +E+ L+ R ++ + L + ++ + QL E++S W V ++ RL+ A A + +L ++ +EH+LR +P++EK + M+ H F K+L + E + + ++ +I+ AYP+A IK++++II+ +W ++ W+ R L+ HL L + +++LL WL+ EGTLL + +L + + +H+ F+ + +Q + D ++ ++K KTP I P DR R + +++ F +P+ L +KW+ VW + R++ L DH+ YLK+VE +NF+++DWR+R++ +MNH KSR+ D FR+ D D++G + R FIDGI+++KF T+ +EM+ VAD+FD+ G ID+++F+AALRPD + + KPAN+++ IHDEVK+ + CTC +++ Q G+GKY+FGD++KLRLVRILRS VMVR+GGGW ALDEFL K+DPCR AKGRTN ELRE+ G +MA F + +T P A S SSP H P S + P R ++IP SR S+S S TP ++ +PG R P +R S+QGS+ +RH S Sbjct: 2844 KLLERVKAIREELTNLSKPLQSLKALAKDISAEARAAGGDADHLTSEVDGLADRMSELQGRLDDRCGELQSAATAVSQFNEQMKSLGIDLNDLETEIEKLSPPGREIKIVQVQIDDVGKIQTKLDRLVGRLEDAERAADVLVDAGFAADTTQTREQISTLRKTLGRLDN----------RVRDHEDNLHSTLKALREFYDHQSQTLDDIQDVSDEFKRMKPVGSELDQIRRQQEDFRNFRERKVEPLAINVDKVNVAGRDLVRSAGSGVSTTAIEKDLEKLNDRWNDLKERMNERDRRLDVALLQSGKFQEALAGLSKWLSDTEEMVANQKPPSSDYKVVKAQLQEQKFLKKMLLDRQNSMGSLANLGKEVANHCEPGERASIEKQLNDLMKRFDALTDGAEQRELDLEEAMEVAKRFHDKISPLELWLDNTERSVKAMELIPT-DEEKIQQRIREHDRLHDEILGKKPDFSDLADVTAQLMHLVSDEEAVNLGEKVRGVTERYTGLVDA---SDNIGALLAESRQGLRHLVLSYQDLVAWMESMEAELKRFKSVPVYAEKLLEQMDHLLELNENIAGHASNVESTVESGAELMKHISNDEAIQLKDKLDSLQRRYGDLTNRGGDLLKSAQNALPLVQQFHEAHNRLVEWMQSAEAALAPSEPRQADVLRLEGELADMRPILDSINQVGPQLCQ----------LSPGEGA-ATIESIVTRDNRRFDSIVEQIQRKAERLHLSNQRAKEVTGDIDELLEWFREMDTTLREA------DLPAME------PKLVRAQLQEHRSINDDISSQKGRVRDVTAASKKVLRESPQSENTATLREKLDDLKEIVDTVAQLCSERLGILEQALPLSEHFADSHQGLTAWLDDMEQQISRLSMPALRPDQITLQQDKNERLLQSIAEHKPLLDKLNKTGEALGALVADDDGAKINEILDTDNARYAALRLELRERQQALESALQESSQFSDKLEGMLRALANTVDQVNQLDPLSALPQKIREQIEDNDALMDDLDKRQDAFSAVQRAANDVIA--KAGNKADPAVR-------------DIKAKLEKLNNLWNDVQNATKKRGSSLDDILSVAEPFWKQLNSVMKTLKDLEETLSCQEPPAAQPQDIKKQQVALQEIRHEIDQTKPEVEQVRRHGSNLMNMCGEPDK-PEVKKHIEDLDNAWDNITALYAKREENLIDAMEKAMEFHETLQNLLKFLTKAEDKFAHLGAVGSDIDAVKRQIEQLKSFKDEVDPHMVEVEALNRQAVELTERTSPEQAASIREPLSVVNRRWEALLRGMVERQKQLEHALLHLGQFQHALNELLVWINKTDSTLDQLKPIPGDPQLLEVELAKLKVLANDIQAHQNSVDTLNDAGRQLIETEKGSVEASTTQEKLRKLNNEWKQLLQKASDRQHELEEALREAHGYIAEVQDILGWLGDVDAVIGASKPVGGLPETATEQLERFMEVYNELDENRPKVETIQAQGQEYIKRQNQMKVSS--SNLQHTLRTLKQRWDAVVSRASDKKIKLEIALKEATEFHDTLQAFVEWLTQAEKLLSNAEPVSRVLETIQAQMEEHKVLQKDVSTHREAMLLLDKKGTHLKYFSQKQDVILIKNLLVSVQHRWERVVSKAAERTRALDHGYKEAREFNDAWSGMMQYLQETEQVLDQIIEEATASKEPQKIKKYIGKLKETHRQLGAKQSVYDGTMRTGKNLLERAPKGDRPVLDKMLIELKEQWTRVWSKSIDRQRKLEEALLLSGQFSDALGELLDWLKKAKSRLNENGP-VHGDLETVQGLCEHHKHIEQDLQKRAAQMQGVLKTGRDL--ERSGNNPEVGRQLDEMQSIWEEVKSAVAKRGERLQVALVDAEKLNARVQALFDWLDHAEHKLRYAKNAPDDEK--VSREMMDIHMDFMKDLRVREREKTETFEYAEDIINKAYPDAIPIIKNWLSIIQQRWEEVRQWAINRESKLEQHLQSLKDLDDTIEELLAWLSGLEGTLLNLKHEQLPDEIPPVEKLIEDHKEFMENTARRQNEVDRACKPRQLPPGARKPSRSGKTPVRITPTRDTPDRDRLPHYGPRFSPSTSGPELE---FRSPRAKLLWTKWRDVWMLSWERQRLLNDHLLYLKDVERARNFSWDDWRKRFLKYMNHKKSRLTDLFRKMDKDNNGMIPRDVFIDGILNTKFDTSGLEMKAVADLFDRNGEGLIDWQEFIAALRPDWQ--ERKPANDSDKIHDEVKRLVMLCTCRQKFRVFQVGEGKYRFGDSQKLRLVRILRSTVMVRVGGGWVALDEFLQKNDPCR----------------------AKGRTNIELREQFILADGVSQSMAAFTPRRST-------PNAAATAS-------SSPHAHNGGSSNLPPYMSGQGPIIKVRERSVRSIPMSRPSRSSLSASTPDSLSDNEGSHGGPSGRYTPRKVTYTSTRTGLTPGGSRAGSKPNSRPLSRQGSKPPSRHGS 5238 HSP 2 Score: 476.863 bits (1226), Expect = 1.522e-133 Identity = 361/1309 (27.58%), Postives = 643/1309 (49.12%), Query Frame = 3 Query: 354 INLLQLDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDI--------EEKIYQFRN---QYADLYANLNSALEELNDDF------------DHNDFRID-FNQTRLENNYLTYLKQYESFCHLFDDISKVDRNNENQRKFHTISTLWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDGYPADQHYRIIININGKIDKVKKKFEKLSPPTLSSGV--ISNRQYTPIH-------------SMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTF-----NEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANIDENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKDVPTNLDQLISAVTTSRQNQKDVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFESKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYE 4118 +++LQLDP DR VLR+ADERDA+QK+TF W+N HL K N+RV D+F DLRDG LL+LLEVLS + L + RFH L+N LDFLR + IKLVNI AED+VDGNPKLTLGL+W IIL FQ DIV K D++S ++ LL+W+R++ YP + + +F++SW+DG AF AL+H+ RPDL+D + + ++ LE AF+ +KE GV ++++PEDV + DEKS++TY++SL+++ P+ I + +++++R+ Q+ + L+E + F D FR D + + E + L + Y+ F+ + +VD E + + I W + T +++ +IL E ++++R ++++ + E + K+ ++E +I + + + + + ++ E+ E I +M L YP + ++ K++K+ +++ +L ++ V +S +Y P+H S ++ N + L + W K + ++ +DL + +KI ++F T + K S DE + + Q N L+ + EL +K +D S FL +++ + W+ KE +I W D + + L ++NL+ ELE RE + G L H A+ I+ L L+ +W W+L LT CL+ HL+ Y QFF E +A+ + + LNS+F + GLD+GE L R ++D+ E + + ETV + +Q+V L+ R + ++ V+AIC+ K+ Q +GE + L +NSG WRV ++ + P C L+ +A A L F LW K+ L+LR+ ++ +T+ +VK W + F + P R I LN DA++L L + ++ ++ + +++ N F E + R + + S + E ++ +L+D M +EL + +P+ D+D LE + H ++E L EP++ L + +T LK L+ +++LW++L ++ + +LK E + L++ + VI E+E L +++ P+ + ++ + QL QD I+ + + DQL R D+++L ++ + R+ + NQ+ +R+ L++ ++ ++W+ G T S + + +E + K+ +E KP+I+ +N + + + Y+ Sbjct: 16 LSILQLDPADRAVLRIADERDAIQKKTFTKWVNKHLKKANRRVVDLFEDLRDGHNLLSLLEVLSGEHLPREKGKMRFHMLQNAQMALDFLRYKKIKLVNIRAEDIVDGNPKLTLGLIWTIILHFQISDIV-VGKEDNVSAREALLRWARRSTARYPGVRVNDFTSSWRDGLAFSALVHRNRPDLLDWRKARNDRPRERLETAFHIVEKEYGVTRLLDPEDVDTNEPDEKSLITYISSLYDVFPEPPSIHPLFDMESQRRVHEYRDLAQQFIYWCREKTAYLQERS--FPPTLIEMKRLLSDLQRFRSDEVSARKREKSKLIQI--YKELERYFETVGEVD--VEAELRPDAIEKAWYRMNTALQDREVILQQEIERLERLQRLADKVQREIKHVDQKLTDLEGRIGEEGRRIERLHPVDAKSIVEALETEIRHLEEPIQDMNQDCHVLNEGRYPH------VSELHKKVNKLHQRWAQLRTNFHTNLVQKLSGLKY-PVHETTVTRQTRMVVESRQIDTNPHFRDLQEHIEWCQNKLKQLLAADYGSDLPSVKEELDRQQHEHKIIDQFHTKILNDERQQTKFSGDELAL-------------YQQRLNQLQKVYAELLSTSTKRLSDLDSLQHFLGQASAELQWLNEKEQVEITRDWADKQ-LDLPSVHRYYENLMSELEKREMHFATILDRGEALLNQQHPASKCIEAHLTALQQQWAWLLQLTLCLEVHLKHATEYHQFFGEIKDAEQWLAKRDEILNSKFSQS-DFGLDQGETLLRGMQDLREELNAFGETVATLQRRAQTVVPLNKRRQPV--NRQGPVQAICAYKQQGQL---QIEKGETVTLLDNSGRVKWRVRTAKGQEGPIPGACLLLPPPDQEAIDAAERLKRLFDRSVALWQKKHLRLRQNMIFATIRVVKGWDFDQFLAMGPEQRTAIRRALNDDADKL---LSEGDPNDPQLRRLRREMDEVNRLFDEF--------EKRARAEEESKQASRIFTEECLAIKSKLED-------MARELDQIILAPLPRDLDSLEHVLEIHSDYERRLHLLEPELKHLQETFRTIALKTPVLKKSLDNLMELWKELNTQSGLHKDRLKLLEASLAGLEDNEHVISELENELA-RHQDLPSTAEGLQQVFKQLNHMQDIITQQQPQMDKMNDAADQL------GRMGVPTKVLGDLKRLHSNVERLNTRWSAVCNQLGERMRSCETAIGLMKNLQSSVQVEESWVDGT-TERLSAMPTATSAYE-------LDKLLGAAIE---RKPKIENVNVAGGRLIREAKIYD 1254 HSP 3 Score: 113.62 bits (283), Expect = 7.193e-24 Identity = 231/1074 (21.51%), Postives = 474/1074 (44.13%), Query Frame = 3 Query: 8433 LNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRS-RLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNV-----KSVEDLQKSLTDLKLLDN------EFAS----YNNDIRVLIGSKIKFIDK----INKLEEQRKKFSD-LVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQ-------KILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIK-NIGSLSLDPKYINEQERLIQTILAEISSRQPFLENV------LMNNAS------RNEPKLKELDDKIKQKLLVASNIEAK-VNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPL---SPTSITKQPTTAN--RQXXXXXXXXXXXXXXADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQ--DLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEE-------IQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKID 11486 ++E NQ ++ + + +E SQQ V T + +I + ++ D + LE + L++ ++ +N+R+ RLL RL KL+ +D S+ +++ED ++SL+DL L + EF S + D+R + + KF+D+ + L + R + L V +S+ +S QE++ + Q YK L+++ + + + L +Q++ + + E L+ +I+S + + L+ E++S+ +++ + +L N ++SL + E I+ PI N + + L E + +++ + + ++++L W+ + + + K N+ SL + + EQ R + +LA++ S Q +++V L+ +AS + E L ++ K +KL +N + ++D L + + + +A E L R L E+ +++E+ + E + K+L+S + D + ++ LE W ++N I+ R+K + Y LK +++ L + E ++ P+AIDL ++ QH++++ ++ P I++ IG++YD+++ + SP RK S T PL S + + PT S S SS D L+ E S ++++I +RY IG +L +R+ ++ L + + K + L+ +L V N + I+ R + + +L + T Q D+LR + VPG +L+ + D +++K+ +L D K + + G +K +++ KERML VLGP+ + +Q+QQV L +E + +K + +G +++ ++ T + +E L + K D+L L DR ++ SK+F +N + + L + + +D + T D +E ++ +L+ + +L + E + TL + D + ++ ++V+ L + +Q K+D Sbjct: 1561 IDELRNQ--INALKQIKDEIESQQRPVATCLEQIRQIVLTGGDVLSAPEVTTLENSGRELRSRVDR----VNDRTVRLL-----------RRLEAGRDELTKLRSELDVFSDWLQVARRTLEDKERSLSDLTRLPSQADSVREFVSDVIGHQADLRFITMAAQKFVDESKEFLAILNDFRTSLPERLPHVEPLSSAESPIRQEVS-----LVSAQ------YKDLLNRVNALQDRVSGLGGRQREYQDALDKANEWLRSVHPRVSRIISEPIAGDPKGVQDQMNEAKALHNELLSSGRLVDNAQQALDNLLRSLGGQLSPME-INQLELPIADLKNNYQQLLDNLGEHCKTLDKTLVQSQGVQDALDSLVGWVNQAEDKFKMNLRPASLIKERLQEQIREHKVLLADLQSHQASIDSVQVSAKHLLASASNARIAKKVESNLNDVTVKF-EKLYEKANKRGEFLDDVYNRLSRYLDEISTVEQRMASLQEALDSRETSLLSTEELARRMNELSRDKDQLAPQFEDCVRSGKDLISLRDVTDTGVLRDRIKALESQWRNINISIDERAKLSKQKAEQQLAYEGLKDQVLSWLASTEARVNGLPPVAIDLDRIKQQHDELKPICKDYRDYAPTIDKINDIGAQYDALI-----------RPESPARKRSTYSPIKRTSPLRRMSGDARSPSPTKGGILSPLSTGSSGFGSRRSSQDGFQLS-ELSPVQQQLSEINNRYGLIGVRLNDRQHELDNLNEELRKQYENLKGLAQFLERIQRQLPKESVSNKDEAERCIKQARKILEDMYEKQSLLDT-TKAQVKDILRRKSDVPGAEQLRQENDSIQEKWKNLNDICKNRIAFSEKLRDFLDTHGNLKSWLDS----KERMLTVLGPISSDPRMVQSQVQQVQVLREEFRTQQPQLKHFQELGHDVVDHLAGT-PDAQAVEIKLKDILGKWDDLVGKLDDRANSLGGAADSSKEFDAAVNRLREALQNISDNLD----TLPTDGDHQENLRKIENLERQLEGQRPLLADVEQSAATLCNILGDPASRADVNSRVAALEKQYLALQKKLD 2582 HSP 4 Score: 85.8853 bits (211), Expect = 1.619e-15 Identity = 341/1856 (18.37%), Postives = 761/1856 (41.00%), Query Frame = 3 Query: 12783 IIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSE--------QKVDPLKKQLEE----LIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDL--------DAEEEPSIEYHKS--KSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND---DSSIDESIKKLKIIINKVDGVFSENVSID---TKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFE---SAMKDLKLNIVDPY---QTRDIWEESLNLVKEVKSHEETLKNLD----QVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDI-----FVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNF----EQKINEMSDQINNDY-------SELEECKI---DFTNLLSAWNEQK-ESINSTIND----SKKLIRQA-PGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYD--LDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKL----AKISSSNKGLQSQTMEYKEKIMNLLSLANEF--WNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQR--LEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKR----FMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATH-LKYISQKHDIVL--IRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQ-SEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGS-IKHYINIIKSQWSDLLSWSEQRGLNLKDHL 18104 ++ +DDR NSL EF++ N L + L N S N+ +K++ L++QLE L D+ ++ +T+ + LG +++S + ++ Q ++ ++ +D K + + + SL + + F EN S+ L + + + HK + Q+++H + + R+ + L G DL T + ++ +LD + ++E L A ++ R ++ K + E L WL TAE LA+ T + ++E R+++ + +++ S E+ K L F + ID K ++ + DR+ + + L ++ D++ + +L E +A L DP + + I EE NL K ++S + K++ G D ++SE D A +++ L D+ + +++ +F N ++ + L L E + L+ R ++I++ + + V K+ + LD+L V E++ E+ D+ F + + +E ++ + K +G + + E+NL ++ L F Q ++++ D +++++ SEL++ + DF N + E+K E + ++ + L+R A G +++ ++++ + + + + ++LD A+ + +F + L WL +TEE + K + D + QE K L D++ + + G ++ + +I + D KR++ + + + R DLE+ + + ++K+ L+N + EK+ + + D L+D L K F D + + + + +++V + + + ++ A ++ S +GL+ + Y++ + + S+ E + + + +K E HL +L E++ G H ++ + G +L++ ++N +E ++ + L+R + + + + + L+ + E +L EW + L P+E P + + + D+ P ++ INQ+G QL + S + S + R N + +++ + ++ +L E +DE +EW + +L + + + L +H+ I D++ + V + + ++++E S + AT R L+ L++ + + + + LE AL + F Q ++ +D++ ++ PD Q + I P L+ + A ++ I + ++ D ++ ++ R+ LE A++ F + + L T +NQ P+S + I EQ+E + AL D+ ++ + + A + K D + I+ + +++ W V + + +R +LD A+ F +++ + E L P I++Q +E + + RR G L + D ++ + + +L W ++ +RE+ L DA+ + + + + NLL +L E K + G D++ V+ + + + ++ +E +N A+ L + S E ++ I + L+ + W + + E++++LE A +F+ N L + +K++ L Q P + +L+ ++ + ++ ++ ++ G +++ + E S + + + ++W LL + R L++ L Sbjct: 2471 LVGKLDDRANSLGGAADSSKEFDAAVN-------------RLREALQNISDNLDTLPTDGDHQENLRKIENLERQLEGQRPLLADV-EQSAATLCNILGDPASRADVNSRVAALEK--QYLA-LQKKLDTK---KAETEASLRDGRHFAENCSKTLGWLGGELSNLTDRLLVSAHKPTLQHQIDTHEPIYREVMAREHEVIMLINKGKDL---TDRQQDRGVKRDLDRIQQQWEKLRREAVDRHTRLQTCMEHCKKYSQTSETFLAWLRTAEDKLADL-TPGVLSKAKLETRLRDLQTFRSEVWKHSGEFENTKGL-------GETFLSSCDIDKEPIKAELQDIRDRWERLNNDLIARAHEIENCSRRLDDFNDELRNLDHSLGRCEDRLAAHDALGGAAKDPKLLERVKAIREELTNLSKPLQSLKALAKDISAEARAAGGDADHLTSEVDGLA--DRMSELQGRLDD-------RCGELQSAATAVSQF---NEQMKSLGIDLNDLETEIEKLSPP--GREIKIVQVQIDDVGKI----QTKLDRL--VGRLEDA-ERAADVLVDAGFAADTTQTREQISTLRK---TLGRLDNRVRDHEDNLHSTLKALREFYDHQSQTLDDIQD-VSDEFKRMKPVGSELDQIRRQQEDFRN----FRERKVEPLAINVDKVNVAGRDLVRSAGSGVSTTAIEKDLEKLNDRWNDLKERMNERDRRLDVALLQSGKFQEALAGLSKWLSDTEEMVANQKPPSSDYKVVKAQLQEQKFLKKMLLDRQNSMGSLANLGKEVANHCEPGERASIEKQLNDLMKRFDALTDGAEQRELDLEEAMEVAKRFHDKISPLELWLDNTERSVKAMELIPTDEEKIQQRIREHDR-LHDEILGKKPDFSD-----LADVTAQLMHLVSDEEAVNLGEKVRGVTERYTGLVDASDNIGALLAESRQGLRHLVLSYQDLVAWMESMEAELKRFKSVPVYAEKLLEQMDHLL----------------ELNENIAG----HASNVESTVESGAELMKHISN-DEAIQLKDKLDSLQRRYGDLTNRGGDLLKSAQNALPLVQQFHEAHNRLVEWMQSAEAAL-----APSE--PRQADVLRLEGELADMRPI---LDSINQVGPQLCQLSPGEGAATIESIVTRDNRRFDSIVEQIQRKAERLHLSNQRAKEVTGDIDELLEWFREMDTTLREADLPAMEPKLVRAQLQEHRSINDDISSQKGRVRDVTAASKKVLRESPQS-ENTATLREKLDDLKEIVDTVAQLCSERLGILEQALPLSEHFADSHQGLTAWLDDMEQQISRLSMPALRPDQITLQQDKNERLLQSIAEHKPLLDKLNKTGEALGALVADDDGAKINEILDTDN----ARYAALRLELRERQQALESALQESSQFSDKLEGMLRALANTVDQVNQLDPLSALPQKIREQIEDNDALMDDLDKRQDAFSAVQRAANDVIAKAGNKADPAVRDIKAKLEKLNNLWNDVQNATKKRGSSLDDILSVAEPFWKQLNSVMKTLKDLEETLSCQEPPAAQPQDIKKQQVALQEIRHEIDQTKPEVEQVRRHGSNLMNMCGEPDKPEVKKHIEDLDNAWDNITALYAKREENLIDAMEKAMEFHETLQNLLKFLTKAEDKFAHLGA-VGSDIDAVKRQIEQLKSFKDEVDPHMVEVEALNRQAVELTERTSPEQAASIREPLSVVNRRWEALLRGMVERQKQLEHALLHLGQFQHALNELLVWINKTDSTLDQLKPIPGD--PQLLEVELAKLKVLANDIQAHQNSVDTLNDAGRQLIETEKGSVEASTTQEKLRKLNNEWKQLLQKASDRQHELEEAL 4221
BLAST of Dystonin vs. Ensembl Fly
Match: shot (gene:FBgn0013733 transcript:FBtr0273225) HSP 1 Score: 848.966 bits (2192), Expect = 0.000e+0 Identity = 654/2496 (26.20%), Postives = 1245/2496 (49.88%), Query Frame = 3 Query: 12297 KLESEIKTTQSDMHLIKPDMENTKLL---IASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAE-----------QKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANND-----PELAKL--LNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEES---LNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALV-----RENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTIND-----------SKKLIRQAPGSD-LKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ-RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTF----PKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILER---DTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHD------EIITNSKK-----KTPPLI------PIFDR----SKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQ-------PVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVA---------------------------SPGLQRKSRIP-TRQTSQQGSQASTRHQS 19469 KL +K + ++ + +++ K L I++ A+ + +A L E++ + +R L L + L S A+ + +++ +L +I+ ++ ++ QI D+ ++ + + + L + + + L + ++I T K++ ++DN + D +++L K + EF ++ + I + +++ P ++L + ++ F E+KV+PL ++++ G + SG+ +E++++ + ++ L + +++ + +D+ L++ KF +L L +++ + + ++ PS +Y K+QL + L L RQ+S+ L G ++ + + +++ ++ +L++L +++ L + AE + + A++++K F D P +WLD E+++ + PT D ++++RI+E+ L ++ L + ++ + S+ +++ K+ + +R++ + + + V ++D + ES +LK P + E+ L L + + H +++ + G +L + S +++ + K++ L + +++ L +N++P+ ++F A+N+L + S A + R+ D L + +M + + N V +CQ + E + +E I + +RF ++ ++ +KA ++ + +AK ++D+ +E + + E D +E L+ A ++ SIN I+ SKK++R++P S+ +L+ +D +K+ ++ + + L++A+PL++ F S+ L WL + E+ + + + L PDQ+ + + + L S + KPLLD + K+G L +V G I ++ RY ++ ++ R LE + +++ ++K++ L N D++ S P+K+ E++ D ++ DLDK Q +Q + K N D +V + KL K+++ +Q+ T + + ++LS+A FW L + ++ L+ + + ++ ++++R EID + ++ ++ + G L+ P++ P+V++ E+L ++ + + ++ N+ + E L ++ + ++ LG + ++ V QI++ K K++++P ++E +N+ +LT+ + P + L+ +N W LL G+ +RQ QL+ LL LG+F A++E + WI T+++L +K GD LE+ LA+ K++ D+ Q SV + ++I+ + S+ TQ +L +L W++L + A + ELE+AL+EA + + Q+I + ++ + + K GGLP+TA EQL+RFM++Y PK+ + E ++ S ++ + L ++WD V + A +K +LE A++ FH + F+ WLT EK L+ PVSR++ TI Q+E H+ L++D+++HRE ML LDK THLKY SQK D++LI+NL+ S+ HRWE+VVS+++ER+R LD+GYKEA+ F D ++ + ++L++ + + + P KI++ I K KE H LG YD T R G L ++AP D +D+++ L+ +W + +KSI+R++ L +ALLLSG + DA+ LL WL+ + +L+++ GD+ TVQ L H +E+ L+ R ++ + L + ++ + QL E++S W V ++ RL+ A A + +L ++ +EH+LR +P++EK + M+ H F K+L + E + + ++ +I+ AYP+A IK++++II+ +W ++ W+ R L+ HL L + +++LL WL+ EGTLL + +L + + +H+ F+ + +Q + D ++ ++K KTP I P DR R + +++ F +P+ L +KW+ VW + R++ L DH+ YLK+VE +NF+++DWR+R++ +MNH KSR+ D FR+ D D++G + R FIDGI+++KF T+ +EM+ VAD+FD+ G ID+++F+AALRPD + + KPAN+++ IHDEVK+ + CTC +++ Q G+GKY+FGD++KLRLVRILRS VMVR+GGGW ALDEFL K+DPCR AKGRTN ELRE+ G +MA F + +T P A S SSP H P S + P R ++IP SR S+S S TP ++ +PG R P +R S+QGS+ +RH S Sbjct: 2955 KLLERVKAIREELTNLSKPLQSLKALAKDISAEARAAGGDADHLTSEVDGLADRMSELQGRLDDRCGELQSAATAVSQFNEQMKSLGIDLNDLETEIEKLSPPGREIKIVQVQIDDVGKIQTKLDRLVGRLEDAERAADVLVDAGFAADTTQTREQISTLRKTLGRLDN----------RVRDHEDNLHSTLKALREFYDHQSQTLDDIQDVSDEFKRMKPVGSELDQIRRQQEDFRNFRERKVEPLAINVDKVNVAGRDLVRSAGSGVSTTAIEKDLEKLNDRWNDLKERMNERDRRLDVALLQSGKFQEALAGLSKWLSDTEEMVANQKPPSSDYKVVKAQLQEQKFLKKMLLDRQNSMGSLANLGKEVANHCEPGERASIEKQLNDLMKRFDALTDGAEQRELDLEEAMEVAKRFHDKISPLELWLDNTERSVKAMELIPT-DEEKIQQRIREHDRLHDEILGKKPDFSDLADVTAQLMHLVSDEEAVNLGEKVRGVTERYTGLVDA---SDNIGALLAESRQGLRHLVLSYQDLVAWMESMEAELKRFKSVPVYAEKLLEQMDHLLELNENIAGHASNVESTVESGAELMKHISNDEAIQLKDKLDSLQRRYGDLTNRGGDLLKSAQNALPLVQQFHEAHNRLVEWMQSAEAALAPSEPRQADVLRLEGELADMRPILDSINQVGPQLCQ----------LSPGEGA-ATIESIVTRDNRRFDSIVEQIQRKAERLHLSNQRAKEVTGDIDELLEWFREMDTTLREA------DLPAME------PKLVRAQLQEHRSINDDISSQKGRVRDVTAASKKVLRESPQSENTATLREKLDDLKEIVDTVAQLCSERLGILEQALPLSEHFADSHQGLTAWLDDMEQQISRLSMPALRPDQITLQQDKNERLLQSIAEHKPLLDKLNKTGEALGALVADDDGAKINEILDTDNARYAALRLELRERQQALESALQESSQFSDKLEGMLRALANTVDQVNQLDPLSALPQKIREQIEDNDALMDDLDKRQDAFSAVQRAANDVIA--KAGNKADPAVR-------------DIKAKLEKLNNLWNDVQNATKKRGSSLDDILSVAEPFWKQLNSVMKTLKDLEETLSCQEPPAAQPQDIKKQQVALQEIRHEIDQTKPEVEQVRRHGSNLMNMCGEPDK-PEVKKHIEDLDNAWDNITALYAKREENLIDAMEKAMEFHETLQNLLKFLTKAEDKFAHLGAVGSDIDAVKRQIEQLKSFKDEVDPHMVEVEALNRQAVELTERTSPEQAASIREPLSVVNRRWEALLRGMVERQKQLEHALLHLGQFQHALNELLVWINKTDSTLDQLKPIPGDPQLLEVELAKLKVLANDIQAHQNSVDTLNDAGRQLIETEKGSVEASTTQEKLRKLNNEWKQLLQKASDRQHELEEALREAHGYIAEVQDILGWLGDVDAVIGASKPVGGLPETATEQLERFMEVYNELDENRPKVETIQAQGQEYIKRQNQMKVSS--SNLQHTLRTLKQRWDAVVSRASDKKIKLEIALKEATEFHDTLQAFVEWLTQAEKLLSNAEPVSRVLETIQAQMEEHKVLQKDVSTHREAMLLLDKKGTHLKYFSQKQDVILIKNLLVSVQHRWERVVSKAAERTRALDHGYKEAREFNDAWSGMMQYLQETEQVLDQIIEEATASKEPQKIKKYIGKLKETHRQLGAKQSVYDGTMRTGKNLLERAPKGDRPVLDKMLIELKEQWTRVWSKSIDRQRKLEEALLLSGQFSDALGELLDWLKKAKSRLNENGP-VHGDLETVQGLCEHHKHIEQDLQKRAAQMQGVLKTGRDL--ERSGNNPEVGRQLDEMQSIWEEVKSAVAKRGERLQVALVDAEKLNARVQALFDWLDHAEHKLRYAKNAPDDEK--VSREMMDIHMDFMKDLRVREREKTETFEYAEDIINKAYPDAIPIIKNWLSIIQQRWEEVRQWAINRESKLEQHLQSLKDLDDTIEELLAWLSGLEGTLLNLKHEQLPDEIPPVEKLIEDHKEFMENTARRQNEVDRACKPRQLPPGARKPSRSGKTPVRITPTRDTPDRDRLPHYGPRFSPSTSGPELE---FRSPRAKLLWTKWRDVWMLSWERQRLLNDHLLYLKDVERARNFSWDDWRKRFLKYMNHKKSRLTDLFRKMDKDNNGMIPRDVFIDGILNTKFDTSGLEMKAVADLFDRNGEGLIDWQEFIAALRPDWQ--ERKPANDSDKIHDEVKRLVMLCTCRQKFRVFQVGEGKYRFGDSQKLRLVRILRSTVMVRVGGGWVALDEFLQKNDPCR----------------------AKGRTNIELREQFILADGVSQSMAAFTPRRST-------PNAAATAS-------SSPHAHNGGSSNLPPYMSGQGPIIKVRERSVRSIPMSRPSRSSLSASTPDSLSDNEGSHGGPSGRYTPRKVTYTSTRTGLTPGGSRAGSKPNSRPLSRQGSKPPSRHGS 5349 HSP 2 Score: 451.825 bits (1161), Expect = 6.130e-126 Identity = 350/1292 (27.09%), Postives = 628/1292 (48.61%), Query Frame = 3 Query: 405 DERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDI--------EEKIYQFRN---QYADLYANLNSALEELNDDF------------DHNDFRID-FNQTRLENNYLTYLKQYESFCHLFDDISKVDRNNENQRKFHTISTLWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDGYPADQHYRIIININGKIDKVKKKFEKLSPPTLSSGV--ISNRQYTPIH-------------SMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTF-----NEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANIDENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKDVPTNLDQLISAVTTSRQNQKDVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFESKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYE 4118 DERDA+QK+TF W+N HL K N+RV D+F DLRDG LL+LLEVLS + L + RFH L+N LDFLR + IKLVNI AED+VDGNPKLTLGL+W IIL FQ DIV K D++S ++ LL+W+R++ YP + + +F++SW+DG AF AL+H+ RPDL+D + + ++ LE AF+ +KE GV ++++PEDV + DEKS++TY++SL+++ P+ I + +++++R+ Q+ + L+E + F D FR D + + E + L + Y+ F+ + +VD E + + I W + T +++ +IL E ++++R ++++ + E + K+ ++E +I + + + + + ++ E+ E I +M L YP + ++ K++K+ +++ +L ++ V +S +Y P+H S ++ N + L + W K + ++ +DL + +KI ++F T + K S DE + + Q N L+ + EL +K +D S FL +++ + W+ KE +I W D + + L ++NL+ ELE RE + G L H A+ I+ L L+ +W W+L LT CL+ HL+ Y QFF E +A+ + + LNS+F + GLD+GE L R ++D+ E + + ETV + +Q+V L+ R + ++ V+AIC+ K+ Q +GE + L +NSG WRV ++ + P C L+ +A A L F LW K+ L+LR+ ++ +T+ +VK W + F + P R I LN DA++L L + ++ ++ + +++ N F E + R + + S + E ++ +L+D M +EL + +P+ D+D LE + H ++E L EP++ L + +T LK L+ +++LW++L ++ + +LK E + L++ + VI E+E L +++ P+ + ++ + QL QD I+ + + DQL R D+++L ++ + R+ + NQ+ +R+ L++ ++ ++W+ G T S + + +E + K+ +E KP+I+ +N + + + Y+ Sbjct: 144 DERDAIQKKTFTKWVNKHLKKANRRVVDLFEDLRDGHNLLSLLEVLSGEHLPREKGKMRFHMLQNAQMALDFLRYKKIKLVNIRAEDIVDGNPKLTLGLIWTIILHFQISDIV-VGKEDNVSAREALLRWARRSTARYPGVRVNDFTSSWRDGLAFSALVHRNRPDLLDWRKARNDRPRERLETAFHIVEKEYGVTRLLDPEDVDTNEPDEKSLITYISSLYDVFPEPPSIHPLFDMESQRRVHEYRDLAQQFIYWCREKTAYLQERS--FPPTLIEMKRLLSDLQRFRSDEVSARKREKSKLIQI--YKELERYFETVGEVD--VEAELRPDAIEKAWYRMNTALQDREVILQQEIERLERLQRLADKVQREIKHVDQKLTDLEGRIGEEGRRIERLHPVDAKSIVEALETEIRHLEEPIQDMNQDCHVLNEGRYPH------VSELHKKVNKLHQRWAQLRTNFHTNLVQKLSGLKY-PVHETTVTRQTRMVVESRQIDTNPHFRDLQEHIEWCQNKLKQLLAADYGSDLPSVKEELDRQQHEHKIIDQFHTKILNDERQQTKFSGDELAL-------------YQQRLNQLQKVYAELLSTSTKRLSDLDSLQHFLGQASAELQWLNEKEQVEITRDWADKQ-LDLPSVHRYYENLMSELEKREMHFATILDRGEALLNQQHPASKCIEAHLTALQQQWAWLLQLTLCLEVHLKHATEYHQFFGEIKDAEQWLAKRDEILNSKFSQS-DFGLDQGETLLRGMQDLREELNAFGETVATLQRRAQTVVPLNKRRQPV--NRQGPVQAICAYKQQGQL---QIEKGETVTLLDNSGRVKWRVRTAKGQEGPIPGACLLLPPPDQEAIDAAERLKRLFDRSVALWQKKHLRLRQNMIFATIRVVKGWDFDQFLAMGPEQRTAIRRALNDDADKL---LSEGDPNDPQLRRLRREMDEVNRLFDEF--------EKRARAEEESKQASRIFTEECLAIKSKLED-------MARELDQIILAPLPRDLDSLEHVLEIHSDYERRLHLLEPELKHLQETFRTIALKTPVLKKSLDNLMELWKELNTQSGLHKDRLKLLEASLAGLEDNEHVISELENELA-RHQDLPSTAEGLQQVFKQLNHMQDIITQQQPQMDKMNDAADQL------GRMGVPTKVLGDLKRLHSNVERLNTRWSAVCNQLGERMRSCETAIGLMKNLQSSVQVEESWVDGT-TERLSAMPTATSAYE-------LDKLLGAAIE---RKPKIENVNVAGGRLIREAKIYD 1365 HSP 3 Score: 114.005 bits (284), Expect = 5.947e-24 Identity = 231/1074 (21.51%), Postives = 474/1074 (44.13%), Query Frame = 3 Query: 8433 LNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRS-RLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNV-----KSVEDLQKSLTDLKLLDN------EFAS----YNNDIRVLIGSKIKFIDK----INKLEEQRKKFSD-LVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQ-------KILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIK-NIGSLSLDPKYINEQERLIQTILAEISSRQPFLENV------LMNNAS------RNEPKLKELDDKIKQKLLVASNIEAK-VNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPL---SPTSITKQPTTAN--RQXXXXXXXXXXXXXXADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQ--DLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEE-------IQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKID 11486 ++E NQ ++ + + +E SQQ V T + +I + ++ D + LE + L++ ++ +N+R+ RLL RL KL+ +D S+ +++ED ++SL+DL L + EF S + D+R + + KF+D+ + L + R + L V +S+ +S QE++ + Q YK L+++ + + + L +Q++ + + E L+ +I+S + + L+ E++S+ +++ + +L N ++SL + E I+ PI N + + L E + +++ + + ++++L W+ + + + K N+ SL + + EQ R + +LA++ S Q +++V L+ +AS + E L ++ K +KL +N + ++D L + + + +A E L R L E+ +++E+ + E + K+L+S + D + ++ LE W ++N I+ R+K + Y LK +++ L + E ++ P+AIDL ++ QH++++ ++ P I++ IG++YD+++ + SP RK S T PL S + + PT S S SS D L+ E S ++++I +RY IG +L +R+ ++ L + + K + L+ +L V N + I+ R + + +L + T Q D+LR + VPG +L+ + D +++K+ +L D K + + G +K +++ KERML VLGP+ + +Q+QQV L +E + +K + +G +++ ++ T + +E L + K D+L L DR ++ SK+F +N + + L + + +D + T D +E ++ +L+ + +L + E + TL + D + ++ ++V+ L + +Q K+D Sbjct: 1672 IDELRNQ--INALKQIKDEIESQQRPVATCLEQIRQIVLTGGDVLSAPEVTTLENSGRELRSRVDR----VNDRTVRLL-----------RRLEAGRDELTKLRSELDVFSDWLQVARRTLEDKERSLSDLTRLPSQADSVREFVSDVIGHQADLRFITMAAQKFVDESKEFLAILNDFRTSLPERLPHVEPLSSAESPIRQEVS-----LVSAQ------YKDLLNRVNALQDRVSGLGGRQREYQDALDKANEWLRSVHPRVSRIISEPIAGDPKGVQDQMNEAKALHNELLSSGRLVDNAQQALDNLLRSLGGQLSPME-INQLELPIADLKNNYQQLLDNLGEHCKTLDKTLVQSQGVQDALDSLVGWVNQAEDKFKMNLRPASLIKERLQEQIREHKVLLADLQSHQASIDSVQVSAKHLLASASNARIAKKVESNLNDVTVKF-EKLYEKANKRGEFLDDVYNRLSRYLDEISTVEQRMASLQEALDSRETSLLSTEELARRMNELSRDKDQLAPQFEDCVRSGKDLISLRDVTDTGVLRDRIKALESQWRNINISIDERAKLSKQKAEQQLAYEGLKDQVLSWLASTEARVNGLPPVAIDLDRIKQQHDELKPICKDYRDYAPTIDKINDIGAQYDALI-----------RPESPARKRSTYSPIKRTSPLRRMSGDARSPSPTKGGILSPLSTGSSGFGSRRSSQDGFQLS-ELSPVQQQLSEINNRYGLIGVRLNDRQHELDNLNEELRKQYENLKGLAQFLERIQRQLPKESVSNKDEAERCIKQARKILEDMYEKQSLLDT-TKAQVKDILRRKSDVPGAEQLRQENDSIQEKWKNLNDICKNRIAFSEKLRDFLDTHGNLKSWLDS----KERMLTVLGPISSDPRMVQSQVQQVQVLREEFRTQQPQLKHFQELGHDVVDHLAGT-PDAQAVEIKLKDILGKWDDLVGKLDDRANSLGGAADSSKEFDAAVNRLREALQNISDNLD----TLPTDGDHQENLRKIENLERQLEGQRPLLADVEQSAATLCNILGDPASRADVNSRVAALEKQYLALQKKLD 2693 HSP 4 Score: 85.5001 bits (210), Expect = 2.363e-15 Identity = 340/1861 (18.27%), Postives = 762/1861 (40.95%), Query Frame = 3 Query: 12783 IIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSE--------QKVDPLKKQLEE----LIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLD---------------AEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND---DSSIDESIKKLKIIINKVDGVFSENVSID---TKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFE---SAMKDLKLNIVDPY---QTRDIWEESLNLVKEVKSHEETLKNLD----QVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDI-----FVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNF----EQKINEMSDQINNDY-------SELEECKI---DFTNLLSAWNEQK-ESINSTIND----SKKLIRQA-PGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYD--LDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEK----LAKISSSNKGLQSQTMEYKEKIMNLLSLANEF--WNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQR--LEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKR----FMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATH-LKYISQKHDIVL--IRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQ-SEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGS-IKHYINIIKSQWSDLLSWSEQRGLNLKDHL 18104 ++ +DDR NSL EF++ N L + L N S N+ +K++ L++QLE L D+ ++ +T+ + LG +++S + ++ Q ++ ++ +D K + + + SL + + F EN S+ L + +P++++ Q+++H + + R+ + L G DL T + ++ +LD + ++E L A ++ R ++ K + E L WL TAE LA+ T + ++E R+++ + +++ S E+ K L F + ID K ++ + DR+ + + L ++ D++ + +L E +A L DP + + I EE NL K ++S + K++ G D ++SE D A +++ L D+ + +++ +F N ++ + L L E + L+ R ++I++ + + V K+ + LD+L V E++ E+ D+ F + + +E ++ + K +G + + E+NL ++ L F Q ++++ D +++++ SEL++ + DF N + E+K E + ++ + L+R A G +++ ++++ + + + + ++LD A+ + +F + L WL +TEE + K + D + QE K L D++ + + G ++ + +I + D KR++ + + + R DLE+ + + ++K+ L+N + EK+ + + D L+D L K F D + + + + +++V + + + ++ A ++ S +GL+ + Y++ + + S+ E + + + +K E HL +L E++ G H ++ + G +L++ ++N +E ++ + L+R + + + + + L+ + E +L EW + L P+E P + + + D+ P ++ INQ+G QL + S + S + R N + +++ + ++ +L E +DE +EW + +L + + + L +H+ I D++ + V + + ++++E S + AT R L+ L++ + + + + LE AL + F Q ++ +D++ ++ PD Q + I P L+ + A ++ I + ++ D ++ ++ R+ LE A++ F + + L T +NQ P+S + I EQ+E + AL D+ ++ + + A + K D + I+ + +++ W V + + +R +LD A+ F +++ + E L P I++Q +E + + RR G L + D ++ + + +L W ++ +RE+ L DA+ + + + + NLL +L E K + G D++ V+ + + + ++ +E +N A+ L + S E ++ I + L+ + W + + E++++LE A +F+ N L + +K++ L Q P + +L+ ++ + ++ ++ ++ G +++ + E S + + + ++W LL + R L++ L Sbjct: 2582 LVGKLDDRANSLGGAADSSKEFDAAVN-------------RLREALQNISDNLDTLPTDGDHQENLRKIENLERQLEGQRPLLADV-EQSAATLCNILGDPASRADVNSRVAALEK--QYLA-LQKKLDTK---KAETEASLRDGRHFAENCSKTLGWLGGELSNLTDRLLVSAHKPTLQH-----QIDTHEPIYREVMAREHEVIMLINKGKDL---TDRQQDRGVKRDLDRIQQQWEKLRREAVDRHTRLQTCMEHCKKYSQTSETFLAWLRTAEDKLADL-TPGVLSKAKLETRLRDLQTFRSEVWKHSGEFENTKGL-------GETFLSSCDIDKEPIKAELQDIRDRWERLNNDLIARAHEIENCSRRLDDFNDELRNLDHSLGRCEDRLAAHDALGGAAKDPKLLERVKAIREELTNLSKPLQSLKALAKDISAEARAAGGDADHLTSEVDGLA--DRMSELQGRLDD-------RCGELQSAATAVSQF---NEQMKSLGIDLNDLETEIEKLSPP--GREIKIVQVQIDDVGKI----QTKLDRL--VGRLEDA-ERAADVLVDAGFAADTTQTREQISTLRK---TLGRLDNRVRDHEDNLHSTLKALREFYDHQSQTLDDIQD-VSDEFKRMKPVGSELDQIRRQQEDFRN----FRERKVEPLAINVDKVNVAGRDLVRSAGSGVSTTAIEKDLEKLNDRWNDLKERMNERDRRLDVALLQSGKFQEALAGLSKWLSDTEEMVANQKPPSSDYKVVKAQLQEQKFLKKMLLDRQNSMGSLANLGKEVANHCEPGERASIEKQLNDLMKRFDALTDGAEQRELDLEEAMEVAKRFHDKISPLELWLDNTERSVKAMELIPTDEEKIQQRIREHDR-LHDEILGKKPDFSD-----LADVTAQLMHLVSDEEAVNLGEKVRGVTERYTGLVDASDNIGALLAESRQGLRHLVLSYQDLVAWMESMEAELKRFKSVPVYAEKLLEQMDHLL----------------ELNENIAG----HASNVESTVESGAELMKHISN-DEAIQLKDKLDSLQRRYGDLTNRGGDLLKSAQNALPLVQQFHEAHNRLVEWMQSAEAAL-----APSE--PRQADVLRLEGELADMRPI---LDSINQVGPQLCQLSPGEGAATIESIVTRDNRRFDSIVEQIQRKAERLHLSNQRAKEVTGDIDELLEWFREMDTTLREADLPAMEPKLVRAQLQEHRSINDDISSQKGRVRDVTAASKKVLRESPQS-ENTATLREKLDDLKEIVDTVAQLCSERLGILEQALPLSEHFADSHQGLTAWLDDMEQQISRLSMPALRPDQITLQQDKNERLLQSIAEHKPLLDKLNKTGEALGALVADDDGAKINEILDTDN----ARYAALRLELRERQQALESALQESSQFSDKLEGMLRALANTVDQVNQLDPLSALPQKIREQIEDNDALMDDLDKRQDAFSAVQRAANDVIAKAGNKADPAVRDIKAKLEKLNNLWNDVQNATKKRGSSLDDILSVAEPFWKQLNSVMKTLKDLEETLSCQEPPAAQPQDIKKQQVALQEIRHEIDQTKPEVEQVRRHGSNLMNMCGEPDKPEVKKHIEDLDNAWDNITALYAKREENLIDAMEKAMEFHETLQNLLKFLTKAEDKFAHLGA-VGSDIDAVKRQIEQLKSFKDEVDPHMVEVEALNRQAVELTERTSPEQAASIREPLSVVNRRWEALLRGMVERQKQLEHALLHLGQFQHALNELLVWINKTDSTLDQLKPIPGD--PQLLEVELAKLKVLANDIQAHQNSVDTLNDAGRQLIETEKGSVEASTTQEKLRKLNNEWKQLLQKASDRQHELEEAL 4332
BLAST of Dystonin vs. Ensembl Fly
Match: shot (gene:FBgn0013733 transcript:FBtr0304853) HSP 1 Score: 846.655 bits (2186), Expect = 0.000e+0 Identity = 653/2504 (26.08%), Postives = 1244/2504 (49.68%), Query Frame = 3 Query: 12297 KLESEIKTTQSDMHLIKPDMENTKLL---IASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAE-----------QKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANND-----PELAKL--LNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEES---LNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALV-----RENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTIND-----------SKKLIRQAPGSD-LKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ-RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTF----PKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILER---DTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHD------EIITNSKK-----KTPPLIPIFD------------------RSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQ-------PVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVA---------------------------SPGLQRKSRIP-TRQTSQQGSQASTRHQS 19469 KL +K + ++ + +++ K L I++ A+ + +A L E++ + +R L L + L S A+ + +++ +L +I+ ++ ++ QI D+ ++ + + + L + + + L + ++I T K++ ++DN + D +++L K + EF ++ + I + +++ P ++L + ++ F E+KV+PL ++++ G + SG+ +E++++ + ++ L + +++ + +D+ L++ KF +L L +++ + + ++ PS +Y K+QL + L L RQ+S+ L G ++ + + +++ ++ +L++L +++ L + AE + + A++++K F D P +WLD E+++ + PT D ++++RI+E+ L ++ L + ++ + S+ +++ K+ + +R++ + + + V ++D + ES +LK P + E+ L L + + H +++ + G +L + S +++ + K++ L + +++ L +N++P+ ++F A+N+L + S A + R+ D L + +M + + N V +CQ + E + +E I + +RF ++ ++ +KA ++ + +AK ++D+ +E + + E D +E L+ A ++ SIN I+ SKK++R++P S+ +L+ +D +K+ ++ + + L++A+PL++ F S+ L WL + E+ + + + L PDQ+ + + + L S + KPLLD + K+G L +V G I ++ RY ++ ++ R LE + +++ ++K++ L N D++ S P+K+ E++ D ++ DLDK Q +Q + K N D +V + KL K+++ +Q+ T + + ++LS+A FW L + ++ L+ + + ++ ++++R EID + ++ ++ + G L+ P++ P+V++ E+L ++ + + ++ N+ + E L ++ + ++ LG + ++ V QI++ K K++++P ++E +N+ +LT+ + P + L+ +N W LL G+ +RQ QL+ LL LG+F A++E + WI T+++L +K GD LE+ LA+ K++ D+ Q SV + ++I+ + S+ TQ +L +L W++L + A + ELE+AL+EA + + Q+I + ++ + + K GGLP+TA EQL+RFM++Y PK+ + E ++ S ++ + L ++WD V + A +K +LE A++ FH + F+ WLT EK L+ PVSR++ TI Q+E H+ L++D+++HRE ML LDK THLKY SQK D++LI+NL+ S+ HRWE+VVS+++ER+R LD+GYKEA+ F D ++ + ++L++ + + + P KI++ I K KE H LG YD T R G L ++AP D +D+++ L+ +W + +KSI+R++ L +ALLLSG + DA+ LL WL+ + +L+++ GD+ TVQ L H +E+ L+ R ++ + L + ++ + QL E++S W V ++ RL+ A A + +L ++ +EH+LR +P++EK + M+ H F K+L + E + + ++ +I+ AYP+A IK++++II+ +W ++ W+ R L+ HL L + +++LL WL+ EGTLL + +L + + +H+ F+ + +Q + D ++ ++K KTP D R + + +G + E F +P+ L +KW+ VW + R++ L DH+ YLK+VE +NF+++DWR+R++ +MNH KSR+ D FR+ D D++G + R FIDGI+++KF T+ +EM+ VAD+FD+ G ID+++F+AALRPD + + KPAN+++ IHDEVK+ + CTC +++ Q G+GKY+FGD++KLRLVRILRS VMVR+GGGW ALDEFL K+DPCR AKGRTN ELRE+ G +MA F + +T P A S SSP H P S + P R ++IP SR S+S S TP ++ +PG R P +R S+QGS+ +RH S Sbjct: 2914 KLLERVKAIREELTNLSKPLQSLKALAKDISAEARAAGGDADHLTSEVDGLADRMSELQGRLDDRCGELQSAATAVSQFNEQMKSLGIDLNDLETEIEKLSPPGREIKIVQVQIDDVGKIQTKLDRLVGRLEDAERAADVLVDAGFAADTTQTREQISTLRKTLGRLDN----------RVRDHEDNLHSTLKALREFYDHQSQTLDDIQDVSDEFKRMKPVGSELDQIRRQQEDFRNFRERKVEPLAINVDKVNVAGRDLVRSAGSGVSTTAIEKDLEKLNDRWNDLKERMNERDRRLDVALLQSGKFQEALAGLSKWLSDTEEMVANQKPPSSDYKVVKAQLQEQKFLKKMLLDRQNSMGSLANLGKEVANHCEPGERASIEKQLNDLMKRFDALTDGAEQRELDLEEAMEVAKRFHDKISPLELWLDNTERSVKAMELIPT-DEEKIQQRIREHDRLHDEILGKKPDFSDLADVTAQLMHLVSDEEAVNLGEKVRGVTERYTGLVDA---SDNIGALLAESRQGLRHLVLSYQDLVAWMESMEAELKRFKSVPVYAEKLLEQMDHLLELNENIAGHASNVESTVESGAELMKHISNDEAIQLKDKLDSLQRRYGDLTNRGGDLLKSAQNALPLVQQFHEAHNRLVEWMQSAEAALAPSEPRQADVLRLEGELADMRPILDSINQVGPQLCQ----------LSPGEGA-ATIESIVTRDNRRFDSIVEQIQRKAERLHLSNQRAKEVTGDIDELLEWFREMDTTLREA------DLPAME------PKLVRAQLQEHRSINDDISSQKGRVRDVTAASKKVLRESPQSENTATLREKLDDLKEIVDTVAQLCSERLGILEQALPLSEHFADSHQGLTAWLDDMEQQISRLSMPALRPDQITLQQDKNERLLQSIAEHKPLLDKLNKTGEALGALVADDDGAKINEILDTDNARYAALRLELRERQQALESALQESSQFSDKLEGMLRALANTVDQVNQLDPLSALPQKIREQIEDNDALMDDLDKRQDAFSAVQRAANDVIA--KAGNKADPAVR-------------DIKAKLEKLNNLWNDVQNATKKRGSSLDDILSVAEPFWKQLNSVMKTLKDLEETLSCQEPPAAQPQDIKKQQVALQEIRHEIDQTKPEVEQVRRHGSNLMNMCGEPDK-PEVKKHIEDLDNAWDNITALYAKREENLIDAMEKAMEFHETLQNLLKFLTKAEDKFAHLGAVGSDIDAVKRQIEQLKSFKDEVDPHMVEVEALNRQAVELTERTSPEQAASIREPLSVVNRRWEALLRGMVERQKQLEHALLHLGQFQHALNELLVWINKTDSTLDQLKPIPGDPQLLEVELAKLKVLANDIQAHQNSVDTLNDAGRQLIETEKGSVEASTTQEKLRKLNNEWKQLLQKASDRQHELEEALREAHGYIAEVQDILGWLGDVDAVIGASKPVGGLPETATEQLERFMEVYNELDENRPKVETIQAQGQEYIKRQNQMKVSS--SNLQHTLRTLKQRWDAVVSRASDKKIKLEIALKEATEFHDTLQAFVEWLTQAEKLLSNAEPVSRVLETIQAQMEEHKVLQKDVSTHREAMLLLDKKGTHLKYFSQKQDVILIKNLLVSVQHRWERVVSKAAERTRALDHGYKEAREFNDAWSGMMQYLQETEQVLDQIIEEATASKEPQKIKKYIGKLKETHRQLGAKQSVYDGTMRTGKNLLERAPKGDRPVLDKMLIELKEQWTRVWSKSIDRQRKLEEALLLSGQFSDALGELLDWLKKAKSRLNENGP-VHGDLETVQGLCEHHKHIEQDLQKRAAQMQGVLKTGRDL--ERSGNNPEVGRQLDEMQSIWEEVKSAVAKRGERLQVALVDAEKLNARVQALFDWLDHAEHKLRYAKNAPDDEK--VSREMMDIHMDFMKDLRVREREKTETFEYAEDIINKAYPDAIPIIKNWLSIIQQRWEEVRQWAINRESKLEQHLQSLKDLDDTIEELLAWLSGLEGTLLNLKHEQLPDEIPPVEKLIEDHKEFMENTARRQNEVDRACKPRQLPPGARKPSRSGKTPVRGSSHDLREQSPDGTLRRQSFKGSRDQGLNARKGSTSGPELEFRSPRAKLLWTKWRDVWMLSWERQRLLNDHLLYLKDVERARNFSWDDWRKRFLKYMNHKKSRLTDLFRKMDKDNNGMIPRDVFIDGILNTKFDTSGLEMKAVADLFDRNGEGLIDWQEFIAALRPDWQ--ERKPANDSDKIHDEVKRLVMLCTCRQKFRVFQVGEGKYRFGDSQKLRLVRILRSTVMVRVGGGWVALDEFLQKNDPCR----------------------AKGRTNIELREQFILADGVSQSMAAFTPRRST-------PNAAATAS-------SSPHAHNGGSSNLPPYMSGQGPIIKVRERSVRSIPMSRPSRSSLSASTPDSLSDNEGSHGGPSGRYTPRKVTYTSTRTGLTPGGSRAGSKPNSRPLSRQGSKPPSRHGS 5319 HSP 2 Score: 318.161 bits (814), Expect = 1.367e-85 Identity = 281/1185 (23.71%), Postives = 548/1185 (46.24%), Query Frame = 3 Query: 726 QFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDI--------EEKIYQFRN---QYADLYANLNSALEELNDDF------------DHNDFRID-FNQTRLENNYLTYLKQYESFCHLFDDISKVDRNNENQRKFHTISTLWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDGYPADQHYRIIININGKIDKVKKKFEKLSPPTLSSGV--ISNRQYTPIH-------------SMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTF-----NEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANIDENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKDVPTNLDQLISAVTTSRQNQKDVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFESKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYE 4118 + DIV K D++S ++ LL+W+R++ YP + + +F++SW+DG AF AL+H+ RPDL+D + + ++ LE AF+ +KE GV ++++PEDV + DEKS++TY++SL+++ P+ I + +++++R+ Q+ + L+E + F D FR D + + E + L + Y+ F+ + +VD E + + I W + T +++ +IL E ++++R ++++ + E + K+ ++E +I + + + + + ++ E+ E I +M L YP + ++ K++K+ +++ +L ++ V +S +Y P+H S ++ N + L + W K + ++ +DL + +KI ++F T + K S DE + + Q N L+ + EL +K +D S FL +++ + W+ KE +I W D + + L ++NL+ ELE RE + G L H A+ I+ L L+ +W W+L LT CL+ HL+ Y QFF E +A+ + + LNS+F + GLD+GE L R ++D+ E + + ETV + +Q+V L+ R + ++ V+AIC+ K+ Q +GE + L +NSG WRV ++ + P C L+ +A A L F LW K+ L+LR+ ++ +T+ +VK W + F + P R I LN DA++L L + ++ ++ + +++ N F E + R + + S + E ++ +L+D M +EL + +P+ D+D LE + H ++E L EP++ L + +T LK L+ +++LW++L ++ + +LK E + L++ + VI E+E L +++ P+ + ++ + QL QD I+ + + DQL R D+++L ++ + R+ + NQ+ +R+ L++ ++ ++W+ G T S + + +E + K+ +E KP+I+ +N + + + Y+ Sbjct: 210 EISDIV-VGKEDNVSAREALLRWARRSTARYPGVRVNDFTSSWRDGLAFSALVHRNRPDLLDWRKARNDRPRERLETAFHIVEKEYGVTRLLDPEDVDTNEPDEKSLITYISSLYDVFPEPPSIHPLFDMESQRRVHEYRDLAQQFIYWCREKTAYLQERS--FPPTLIEMKRLLSDLQRFRSDEVSARKREKSKLIQI--YKELERYFETVGEVD--VEAELRPDAIEKAWYRMNTALQDREVILQQEIERLERLQRLADKVQREIKHVDQKLTDLEGRIGEEGRRIERLHPVDAKSIVEALETEIRHLEEPIQDMNQDCHVLNEGRYPH------VSELHKKVNKLHQRWAQLRTNFHTNLVQKLSGLKY-PVHETTVTRQTRMVVESRQIDTNPHFRDLQEHIEWCQNKLKQLLAADYGSDLPSVKEELDRQQHEHKIIDQFHTKILNDERQQTKFSGDELAL-------------YQQRLNQLQKVYAELLSTSTKRLSDLDSLQHFLGQASAELQWLNEKEQVEITRDWADKQ-LDLPSVHRYYENLMSELEKREMHFATILDRGEALLNQQHPASKCIEAHLTALQQQWAWLLQLTLCLEVHLKHATEYHQFFGEIKDAEQWLAKRDEILNSKFSQS-DFGLDQGETLLRGMQDLREELNAFGETVATLQRRAQTVVPLNKRRQPV--NRQGPVQAICAYKQQGQL---QIEKGETVTLLDNSGRVKWRVRTAKGQEGPIPGACLLLPPPDQEAIDAAERLKRLFDRSVALWQKKHLRLRQNMIFATIRVVKGWDFDQFLAMGPEQRTAIRRALNDDADKL---LSEGDPNDPQLRRLRREMDEVNRLFDEF--------EKRARAEEESKQASRIFTEECLAIKSKLED-------MARELDQIILAPLPRDLDSLEHVLEIHSDYERRLHLLEPELKHLQETFRTIALKTPVLKKSLDNLMELWKELNTQSGLHKDRLKLLEASLAGLEDNEHVISELENELA-RHQDLPSTAEGLQQVFKQLNHMQDIITQQQPQMDKMNDAADQL------GRMGVPTKVLGDLKRLHSNVERLNTRWSAVCNQLGERMRSCETAIGLMKNLQSSVQVEESWVDGT-TERLSAMPTATSAYE-------LDKLLGAAIE---RKPKIENVNVAGGRLIREAKIYD 1324 HSP 3 Score: 112.849 bits (281), Expect = 1.261e-23 Identity = 231/1074 (21.51%), Postives = 474/1074 (44.13%), Query Frame = 3 Query: 8433 LNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRS-RLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNV-----KSVEDLQKSLTDLKLLDN------EFAS----YNNDIRVLIGSKIKFIDK----INKLEEQRKKFSD-LVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQ-------KILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIK-NIGSLSLDPKYINEQERLIQTILAEISSRQPFLENV------LMNNAS------RNEPKLKELDDKIKQKLLVASNIEAK-VNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPL---SPTSITKQPTTAN--RQXXXXXXXXXXXXXXADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQ--DLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEE-------IQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKID 11486 ++E NQ ++ + + +E SQQ V T + +I + ++ D + LE + L++ ++ +N+R+ RLL RL KL+ +D S+ +++ED ++SL+DL L + EF S + D+R + + KF+D+ + L + R + L V +S+ +S QE++ + Q YK L+++ + + + L +Q++ + + E L+ +I+S + + L+ E++S+ +++ + +L N ++SL + E I+ PI N + + L E + +++ + + ++++L W+ + + + K N+ SL + + EQ R + +LA++ S Q +++V L+ +AS + E L ++ K +KL +N + ++D L + + + +A E L R L E+ +++E+ + E + K+L+S + D + ++ LE W ++N I+ R+K + Y LK +++ L + E ++ P+AIDL ++ QH++++ ++ P I++ IG++YD+++ + SP RK S T PL S + + PT S S SS D L+ E S ++++I +RY IG +L +R+ ++ L + + K + L+ +L V N + I+ R + + +L + T Q D+LR + VPG +L+ + D +++K+ +L D K + + G +K +++ KERML VLGP+ + +Q+QQV L +E + +K + +G +++ ++ T + +E L + K D+L L DR ++ SK+F +N + + L + + +D + T D +E ++ +L+ + +L + E + TL + D + ++ ++V+ L + +Q K+D Sbjct: 1631 IDELRNQ--INALKQIKDEIESQQRPVATCLEQIRQIVLTGGDVLSAPEVTTLENSGRELRSRVDR----VNDRTVRLL-----------RRLEAGRDELTKLRSELDVFSDWLQVARRTLEDKERSLSDLTRLPSQADSVREFVSDVIGHQADLRFITMAAQKFVDESKEFLAILNDFRTSLPERLPHVEPLSSAESPIRQEVS-----LVSAQ------YKDLLNRVNALQDRVSGLGGRQREYQDALDKANEWLRSVHPRVSRIISEPIAGDPKGVQDQMNEAKALHNELLSSGRLVDNAQQALDNLLRSLGGQLSPME-INQLELPIADLKNNYQQLLDNLGEHCKTLDKTLVQSQGVQDALDSLVGWVNQAEDKFKMNLRPASLIKERLQEQIREHKVLLADLQSHQASIDSVQVSAKHLLASASNARIAKKVESNLNDVTVKF-EKLYEKANKRGEFLDDVYNRLSRYLDEISTVEQRMASLQEALDSRETSLLSTEELARRMNELSRDKDQLAPQFEDCVRSGKDLISLRDVTDTGVLRDRIKALESQWRNINISIDERAKLSKQKAEQQLAYEGLKDQVLSWLASTEARVNGLPPVAIDLDRIKQQHDELKPICKDYRDYAPTIDKINDIGAQYDALI-----------RPESPARKRSTYSPIKRTSPLRRMSGDARSPSPTKGGILSPLSTGSSGFGSRRSSQDGFQLS-ELSPVQQQLSEINNRYGLIGVRLNDRQHELDNLNEELRKQYENLKGLAQFLERIQRQLPKESVSNKDEAERCIKQARKILEDMYEKQSLLDT-TKAQVKDILRRKSDVPGAEQLRQENDSIQEKWKNLNDICKNRIAFSEKLRDFLDTHGNLKSWLDS----KERMLTVLGPISSDPRMVQSQVQQVQVLREEFRTQQPQLKHFQELGHDVVDHLAGT-PDAQAVEIKLKDILGKWDDLVGKLDDRANSLGGAADSSKEFDAAVNRLREALQNISDNLD----TLPTDGDHQENLRKIENLERQLEGQRPLLADVEQSAATLCNILGDPASRADVNSRVAALEKQYLALQKKLD 2652 HSP 4 Score: 84.3445 bits (207), Expect = 5.827e-15 Identity = 340/1861 (18.27%), Postives = 762/1861 (40.95%), Query Frame = 3 Query: 12783 IIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSE--------QKVDPLKKQLEE----LIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLD---------------AEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND---DSSIDESIKKLKIIINKVDGVFSENVSID---TKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFE---SAMKDLKLNIVDPY---QTRDIWEESLNLVKEVKSHEETLKNLD----QVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDI-----FVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNF----EQKINEMSDQINNDY-------SELEECKI---DFTNLLSAWNEQK-ESINSTIND----SKKLIRQA-PGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYD--LDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKL----AKISSSNKGLQSQTMEYKEKIMNLLSLANEF--WNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQR--LEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKR----FMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATH-LKYISQKHDIVL--IRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQ-SEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGS-IKHYINIIKSQWSDLLSWSEQRGLNLKDHL 18104 ++ +DDR NSL EF++ N L + L N S N+ +K++ L++QLE L D+ ++ +T+ + LG +++S + ++ Q ++ ++ +D K + + + SL + + F EN S+ L + +P++++ Q+++H + + R+ + L G DL T + ++ +LD + ++E L A ++ R ++ K + E L WL TAE LA+ T + ++E R+++ + +++ S E+ K L F + ID K ++ + DR+ + + L ++ D++ + +L E +A L DP + + I EE NL K ++S + K++ G D ++SE D A +++ L D+ + +++ +F N ++ + L L E + L+ R ++I++ + + V K+ + LD+L V E++ E+ D+ F + + +E ++ + K +G + + E+NL ++ L F Q ++++ D +++++ SEL++ + DF N + E+K E + ++ + L+R A G +++ ++++ + + + + ++LD A+ + +F + L WL +TEE + K + D + QE K L D++ + + G ++ + +I + D KR++ + + + R DLE+ + + ++K+ L+N + EK+ + + D L+D L K F D + + + + +++V + + + ++ A ++ S +GL+ + Y++ + + S+ E + + + +K E HL +L E++ G H ++ + G +L++ ++N +E ++ + L+R + + + + + L+ + E +L EW + L P+E P + + + D+ P ++ INQ+G QL + S + S + R N + +++ + ++ +L E +DE +EW + +L + + + L +H+ I D++ + V + + ++++E S + AT R L+ L++ + + + + LE AL + F Q ++ +D++ ++ PD Q + I P L+ + A ++ I + ++ D ++ ++ R+ LE A++ F + + L T +NQ P+S + I EQ+E + AL D+ ++ + + A + K D + I+ + +++ W V + + +R +LD A+ F +++ + E L P I++Q +E + + RR G L + D ++ + + +L W ++ +RE+ L DA+ + + + + NLL +L E K + G D++ V+ + + + ++ +E +N A+ L + S E ++ I + L+ + W + + E++++LE A +F+ N L + +K++ L Q P + +L+ ++ + ++ ++ ++ G +++ + E S + + + ++W LL + R L++ L Sbjct: 2541 LVGKLDDRANSLGGAADSSKEFDAAVN-------------RLREALQNISDNLDTLPTDGDHQENLRKIENLERQLEGQRPLLADV-EQSAATLCNILGDPASRADVNSRVAALEK--QYLA-LQKKLDTK---KAETEASLRDGRHFAENCSKTLGWLGGELSNLTDRLLVSAHKPTLQH-----QIDTHEPIYREVMAREHEVIMLINKGKDL---TDRQQDRGVKRDLDRIQQQWEKLRREAVDRHTRLQTCMEHCKKYSQTSETFLAWLRTAEDKLADL-TPGVLSKAKLETRLRDLQTFRSEVWKHSGEFENTKGL-------GETFLSSCDIDKEPIKAELQDIRDRWERLNNDLIARAHEIENCSRRLDDFNDELRNLDHSLGRCEDRLAAHDALGGAAKDPKLLERVKAIREELTNLSKPLQSLKALAKDISAEARAAGGDADHLTSEVDGLA--DRMSELQGRLDD-------RCGELQSAATAVSQF---NEQMKSLGIDLNDLETEIEKLSPP--GREIKIVQVQIDDVGKI----QTKLDRL--VGRLEDA-ERAADVLVDAGFAADTTQTREQISTLRK---TLGRLDNRVRDHEDNLHSTLKALREFYDHQSQTLDDIQD-VSDEFKRMKPVGSELDQIRRQQEDFRN----FRERKVEPLAINVDKVNVAGRDLVRSAGSGVSTTAIEKDLEKLNDRWNDLKERMNERDRRLDVALLQSGKFQEALAGLSKWLSDTEEMVANQKPPSSDYKVVKAQLQEQKFLKKMLLDRQNSMGSLANLGKEVANHCEPGERASIEKQLNDLMKRFDALTDGAEQRELDLEEAMEVAKRFHDKISPLELWLDNTERSVKAMELIPTDEEKIQQRIREHDR-LHDEILGKKPDFSD-----LADVTAQLMHLVSDEEAVNLGEKVRGVTERYTGLVDASDNIGALLAESRQGLRHLVLSYQDLVAWMESMEAELKRFKSVPVYAEKLLEQMDHLL----------------ELNENIAG----HASNVESTVESGAELMKHISN-DEAIQLKDKLDSLQRRYGDLTNRGGDLLKSAQNALPLVQQFHEAHNRLVEWMQSAEAAL-----APSE--PRQADVLRLEGELADMRPI---LDSINQVGPQLCQLSPGEGAATIESIVTRDNRRFDSIVEQIQRKAERLHLSNQRAKEVTGDIDELLEWFREMDTTLREADLPAMEPKLVRAQLQEHRSINDDISSQKGRVRDVTAASKKVLRESPQS-ENTATLREKLDDLKEIVDTVAQLCSERLGILEQALPLSEHFADSHQGLTAWLDDMEQQISRLSMPALRPDQITLQQDKNERLLQSIAEHKPLLDKLNKTGEALGALVADDDGAKINEILDTDN----ARYAALRLELRERQQALESALQESSQFSDKLEGMLRALANTVDQVNQLDPLSALPQKIREQIEDNDALMDDLDKRQDAFSAVQRAANDVIAKAGNKADPAVRDIKAKLEKLNNLWNDVQNATKKRGSSLDDILSVAEPFWKQLNSVMKTLKDLEETLSCQEPPAAQPQDIKKQQVALQEIRHEIDQTKPEVEQVRRHGSNLMNMCGEPDKPEVKKHIEDLDNAWDNITALYAKREENLIDAMEKAMEFHETLQNLLKFLTKAEDKFAHLGA-VGSDIDAVKRQIEQLKSFKDEVDPHMVEVEALNRQAVELTERTSPEQAASIREPLSVVNRRWEALLRGMVERQKQLEHALLHLGQFQHALNELLVWINKTDSTLDQLKPIPGD--PQLLEVELAKLKVLANDIQAHQNSVDTLNDAGRQLIETEKGSVEASTTQEKLRKLNNEWKQLLQKASDRQHELEEAL 4291
BLAST of Dystonin vs. Ensembl Fly
Match: shot (gene:FBgn0013733 transcript:FBtr0304847) HSP 1 Score: 846.655 bits (2186), Expect = 0.000e+0 Identity = 653/2504 (26.08%), Postives = 1244/2504 (49.68%), Query Frame = 3 Query: 12297 KLESEIKTTQSDMHLIKPDMENTKLL---IASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAE-----------QKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANND-----PELAKL--LNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEES---LNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALV-----RENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTIND-----------SKKLIRQAPGSD-LKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ-RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTF----PKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILER---DTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHD------EIITNSKK-----KTPPLIPIFD------------------RSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQ-------PVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVA---------------------------SPGLQRKSRIP-TRQTSQQGSQASTRHQS 19469 KL +K + ++ + +++ K L I++ A+ + +A L E++ + +R L L + L S A+ + +++ +L +I+ ++ ++ QI D+ ++ + + + L + + + L + ++I T K++ ++DN + D +++L K + EF ++ + I + +++ P ++L + ++ F E+KV+PL ++++ G + SG+ +E++++ + ++ L + +++ + +D+ L++ KF +L L +++ + + ++ PS +Y K+QL + L L RQ+S+ L G ++ + + +++ ++ +L++L +++ L + AE + + A++++K F D P +WLD E+++ + PT D ++++RI+E+ L ++ L + ++ + S+ +++ K+ + +R++ + + + V ++D + ES +LK P + E+ L L + + H +++ + G +L + S +++ + K++ L + +++ L +N++P+ ++F A+N+L + S A + R+ D L + +M + + N V +CQ + E + +E I + +RF ++ ++ +KA ++ + +AK ++D+ +E + + E D +E L+ A ++ SIN I+ SKK++R++P S+ +L+ +D +K+ ++ + + L++A+PL++ F S+ L WL + E+ + + + L PDQ+ + + + L S + KPLLD + K+G L +V G I ++ RY ++ ++ R LE + +++ ++K++ L N D++ S P+K+ E++ D ++ DLDK Q +Q + K N D +V + KL K+++ +Q+ T + + ++LS+A FW L + ++ L+ + + ++ ++++R EID + ++ ++ + G L+ P++ P+V++ E+L ++ + + ++ N+ + E L ++ + ++ LG + ++ V QI++ K K++++P ++E +N+ +LT+ + P + L+ +N W LL G+ +RQ QL+ LL LG+F A++E + WI T+++L +K GD LE+ LA+ K++ D+ Q SV + ++I+ + S+ TQ +L +L W++L + A + ELE+AL+EA + + Q+I + ++ + + K GGLP+TA EQL+RFM++Y PK+ + E ++ S ++ + L ++WD V + A +K +LE A++ FH + F+ WLT EK L+ PVSR++ TI Q+E H+ L++D+++HRE ML LDK THLKY SQK D++LI+NL+ S+ HRWE+VVS+++ER+R LD+GYKEA+ F D ++ + ++L++ + + + P KI++ I K KE H LG YD T R G L ++AP D +D+++ L+ +W + +KSI+R++ L +ALLLSG + DA+ LL WL+ + +L+++ GD+ TVQ L H +E+ L+ R ++ + L + ++ + QL E++S W V ++ RL+ A A + +L ++ +EH+LR +P++EK + M+ H F K+L + E + + ++ +I+ AYP+A IK++++II+ +W ++ W+ R L+ HL L + +++LL WL+ EGTLL + +L + + +H+ F+ + +Q + D ++ ++K KTP D R + + +G + E F +P+ L +KW+ VW + R++ L DH+ YLK+VE +NF+++DWR+R++ +MNH KSR+ D FR+ D D++G + R FIDGI+++KF T+ +EM+ VAD+FD+ G ID+++F+AALRPD + + KPAN+++ IHDEVK+ + CTC +++ Q G+GKY+FGD++KLRLVRILRS VMVR+GGGW ALDEFL K+DPCR AKGRTN ELRE+ G +MA F + +T P A S SSP H P S + P R ++IP SR S+S S TP ++ +PG R P +R S+QGS+ +RH S Sbjct: 2914 KLLERVKAIREELTNLSKPLQSLKALAKDISAEARAAGGDADHLTSEVDGLADRMSELQGRLDDRCGELQSAATAVSQFNEQMKSLGIDLNDLETEIEKLSPPGREIKIVQVQIDDVGKIQTKLDRLVGRLEDAERAADVLVDAGFAADTTQTREQISTLRKTLGRLDN----------RVRDHEDNLHSTLKALREFYDHQSQTLDDIQDVSDEFKRMKPVGSELDQIRRQQEDFRNFRERKVEPLAINVDKVNVAGRDLVRSAGSGVSTTAIEKDLEKLNDRWNDLKERMNERDRRLDVALLQSGKFQEALAGLSKWLSDTEEMVANQKPPSSDYKVVKAQLQEQKFLKKMLLDRQNSMGSLANLGKEVANHCEPGERASIEKQLNDLMKRFDALTDGAEQRELDLEEAMEVAKRFHDKISPLELWLDNTERSVKAMELIPT-DEEKIQQRIREHDRLHDEILGKKPDFSDLADVTAQLMHLVSDEEAVNLGEKVRGVTERYTGLVDA---SDNIGALLAESRQGLRHLVLSYQDLVAWMESMEAELKRFKSVPVYAEKLLEQMDHLLELNENIAGHASNVESTVESGAELMKHISNDEAIQLKDKLDSLQRRYGDLTNRGGDLLKSAQNALPLVQQFHEAHNRLVEWMQSAEAALAPSEPRQADVLRLEGELADMRPILDSINQVGPQLCQ----------LSPGEGA-ATIESIVTRDNRRFDSIVEQIQRKAERLHLSNQRAKEVTGDIDELLEWFREMDTTLREA------DLPAME------PKLVRAQLQEHRSINDDISSQKGRVRDVTAASKKVLRESPQSENTATLREKLDDLKEIVDTVAQLCSERLGILEQALPLSEHFADSHQGLTAWLDDMEQQISRLSMPALRPDQITLQQDKNERLLQSIAEHKPLLDKLNKTGEALGALVADDDGAKINEILDTDNARYAALRLELRERQQALESALQESSQFSDKLEGMLRALANTVDQVNQLDPLSALPQKIREQIEDNDALMDDLDKRQDAFSAVQRAANDVIA--KAGNKADPAVR-------------DIKAKLEKLNNLWNDVQNATKKRGSSLDDILSVAEPFWKQLNSVMKTLKDLEETLSCQEPPAAQPQDIKKQQVALQEIRHEIDQTKPEVEQVRRHGSNLMNMCGEPDK-PEVKKHIEDLDNAWDNITALYAKREENLIDAMEKAMEFHETLQNLLKFLTKAEDKFAHLGAVGSDIDAVKRQIEQLKSFKDEVDPHMVEVEALNRQAVELTERTSPEQAASIREPLSVVNRRWEALLRGMVERQKQLEHALLHLGQFQHALNELLVWINKTDSTLDQLKPIPGDPQLLEVELAKLKVLANDIQAHQNSVDTLNDAGRQLIETEKGSVEASTTQEKLRKLNNEWKQLLQKASDRQHELEEALREAHGYIAEVQDILGWLGDVDAVIGASKPVGGLPETATEQLERFMEVYNELDENRPKVETIQAQGQEYIKRQNQMKVSS--SNLQHTLRTLKQRWDAVVSRASDKKIKLEIALKEATEFHDTLQAFVEWLTQAEKLLSNAEPVSRVLETIQAQMEEHKVLQKDVSTHREAMLLLDKKGTHLKYFSQKQDVILIKNLLVSVQHRWERVVSKAAERTRALDHGYKEAREFNDAWSGMMQYLQETEQVLDQIIEEATASKEPQKIKKYIGKLKETHRQLGAKQSVYDGTMRTGKNLLERAPKGDRPVLDKMLIELKEQWTRVWSKSIDRQRKLEEALLLSGQFSDALGELLDWLKKAKSRLNENGP-VHGDLETVQGLCEHHKHIEQDLQKRAAQMQGVLKTGRDL--ERSGNNPEVGRQLDEMQSIWEEVKSAVAKRGERLQVALVDAEKLNARVQALFDWLDHAEHKLRYAKNAPDDEK--VSREMMDIHMDFMKDLRVREREKTETFEYAEDIINKAYPDAIPIIKNWLSIIQQRWEEVRQWAINRESKLEQHLQSLKDLDDTIEELLAWLSGLEGTLLNLKHEQLPDEIPPVEKLIEDHKEFMENTARRQNEVDRACKPRQLPPGARKPSRSGKTPVRGSSHDLREQSPDGTLRRQSFKGSRDQGLNARKGSTSGPELEFRSPRAKLLWTKWRDVWMLSWERQRLLNDHLLYLKDVERARNFSWDDWRKRFLKYMNHKKSRLTDLFRKMDKDNNGMIPRDVFIDGILNTKFDTSGLEMKAVADLFDRNGEGLIDWQEFIAALRPDWQ--ERKPANDSDKIHDEVKRLVMLCTCRQKFRVFQVGEGKYRFGDSQKLRLVRILRSTVMVRVGGGWVALDEFLQKNDPCR----------------------AKGRTNIELREQFILADGVSQSMAAFTPRRST-------PNAAATAS-------SSPHAHNGGSSNLPPYMSGQGPIIKVRERSVRSIPMSRPSRSSLSASTPDSLSDNEGSHGGPSGRYTPRKVTYTSTRTGLTPGGSRAGSKPNSRPLSRQGSKPPSRHGS 5319 HSP 2 Score: 318.161 bits (814), Expect = 1.367e-85 Identity = 281/1185 (23.71%), Postives = 548/1185 (46.24%), Query Frame = 3 Query: 726 QFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDI--------EEKIYQFRN---QYADLYANLNSALEELNDDF------------DHNDFRID-FNQTRLENNYLTYLKQYESFCHLFDDISKVDRNNENQRKFHTISTLWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDGYPADQHYRIIININGKIDKVKKKFEKLSPPTLSSGV--ISNRQYTPIH-------------SMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTF-----NEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANIDENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKDVPTNLDQLISAVTTSRQNQKDVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFESKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYE 4118 + DIV K D++S ++ LL+W+R++ YP + + +F++SW+DG AF AL+H+ RPDL+D + + ++ LE AF+ +KE GV ++++PEDV + DEKS++TY++SL+++ P+ I + +++++R+ Q+ + L+E + F D FR D + + E + L + Y+ F+ + +VD E + + I W + T +++ +IL E ++++R ++++ + E + K+ ++E +I + + + + + ++ E+ E I +M L YP + ++ K++K+ +++ +L ++ V +S +Y P+H S ++ N + L + W K + ++ +DL + +KI ++F T + K S DE + + Q N L+ + EL +K +D S FL +++ + W+ KE +I W D + + L ++NL+ ELE RE + G L H A+ I+ L L+ +W W+L LT CL+ HL+ Y QFF E +A+ + + LNS+F + GLD+GE L R ++D+ E + + ETV + +Q+V L+ R + ++ V+AIC+ K+ Q +GE + L +NSG WRV ++ + P C L+ +A A L F LW K+ L+LR+ ++ +T+ +VK W + F + P R I LN DA++L L + ++ ++ + +++ N F E + R + + S + E ++ +L+D M +EL + +P+ D+D LE + H ++E L EP++ L + +T LK L+ +++LW++L ++ + +LK E + L++ + VI E+E L +++ P+ + ++ + QL QD I+ + + DQL R D+++L ++ + R+ + NQ+ +R+ L++ ++ ++W+ G T S + + +E + K+ +E KP+I+ +N + + + Y+ Sbjct: 210 EISDIV-VGKEDNVSAREALLRWARRSTARYPGVRVNDFTSSWRDGLAFSALVHRNRPDLLDWRKARNDRPRERLETAFHIVEKEYGVTRLLDPEDVDTNEPDEKSLITYISSLYDVFPEPPSIHPLFDMESQRRVHEYRDLAQQFIYWCREKTAYLQERS--FPPTLIEMKRLLSDLQRFRSDEVSARKREKSKLIQI--YKELERYFETVGEVD--VEAELRPDAIEKAWYRMNTALQDREVILQQEIERLERLQRLADKVQREIKHVDQKLTDLEGRIGEEGRRIERLHPVDAKSIVEALETEIRHLEEPIQDMNQDCHVLNEGRYPH------VSELHKKVNKLHQRWAQLRTNFHTNLVQKLSGLKY-PVHETTVTRQTRMVVESRQIDTNPHFRDLQEHIEWCQNKLKQLLAADYGSDLPSVKEELDRQQHEHKIIDQFHTKILNDERQQTKFSGDELAL-------------YQQRLNQLQKVYAELLSTSTKRLSDLDSLQHFLGQASAELQWLNEKEQVEITRDWADKQ-LDLPSVHRYYENLMSELEKREMHFATILDRGEALLNQQHPASKCIEAHLTALQQQWAWLLQLTLCLEVHLKHATEYHQFFGEIKDAEQWLAKRDEILNSKFSQS-DFGLDQGETLLRGMQDLREELNAFGETVATLQRRAQTVVPLNKRRQPV--NRQGPVQAICAYKQQGQL---QIEKGETVTLLDNSGRVKWRVRTAKGQEGPIPGACLLLPPPDQEAIDAAERLKRLFDRSVALWQKKHLRLRQNMIFATIRVVKGWDFDQFLAMGPEQRTAIRRALNDDADKL---LSEGDPNDPQLRRLRREMDEVNRLFDEF--------EKRARAEEESKQASRIFTEECLAIKSKLED-------MARELDQIILAPLPRDLDSLEHVLEIHSDYERRLHLLEPELKHLQETFRTIALKTPVLKKSLDNLMELWKELNTQSGLHKDRLKLLEASLAGLEDNEHVISELENELA-RHQDLPSTAEGLQQVFKQLNHMQDIITQQQPQMDKMNDAADQL------GRMGVPTKVLGDLKRLHSNVERLNTRWSAVCNQLGERMRSCETAIGLMKNLQSSVQVEESWVDGT-TERLSAMPTATSAYE-------LDKLLGAAIE---RKPKIENVNVAGGRLIREAKIYD 1324 HSP 3 Score: 112.849 bits (281), Expect = 1.261e-23 Identity = 231/1074 (21.51%), Postives = 474/1074 (44.13%), Query Frame = 3 Query: 8433 LNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRS-RLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNV-----KSVEDLQKSLTDLKLLDN------EFAS----YNNDIRVLIGSKIKFIDK----INKLEEQRKKFSD-LVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQ-------KILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIK-NIGSLSLDPKYINEQERLIQTILAEISSRQPFLENV------LMNNAS------RNEPKLKELDDKIKQKLLVASNIEAK-VNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPL---SPTSITKQPTTAN--RQXXXXXXXXXXXXXXADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQ--DLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEE-------IQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKID 11486 ++E NQ ++ + + +E SQQ V T + +I + ++ D + LE + L++ ++ +N+R+ RLL RL KL+ +D S+ +++ED ++SL+DL L + EF S + D+R + + KF+D+ + L + R + L V +S+ +S QE++ + Q YK L+++ + + + L +Q++ + + E L+ +I+S + + L+ E++S+ +++ + +L N ++SL + E I+ PI N + + L E + +++ + + ++++L W+ + + + K N+ SL + + EQ R + +LA++ S Q +++V L+ +AS + E L ++ K +KL +N + ++D L + + + +A E L R L E+ +++E+ + E + K+L+S + D + ++ LE W ++N I+ R+K + Y LK +++ L + E ++ P+AIDL ++ QH++++ ++ P I++ IG++YD+++ + SP RK S T PL S + + PT S S SS D L+ E S ++++I +RY IG +L +R+ ++ L + + K + L+ +L V N + I+ R + + +L + T Q D+LR + VPG +L+ + D +++K+ +L D K + + G +K +++ KERML VLGP+ + +Q+QQV L +E + +K + +G +++ ++ T + +E L + K D+L L DR ++ SK+F +N + + L + + +D + T D +E ++ +L+ + +L + E + TL + D + ++ ++V+ L + +Q K+D Sbjct: 1631 IDELRNQ--INALKQIKDEIESQQRPVATCLEQIRQIVLTGGDVLSAPEVTTLENSGRELRSRVDR----VNDRTVRLL-----------RRLEAGRDELTKLRSELDVFSDWLQVARRTLEDKERSLSDLTRLPSQADSVREFVSDVIGHQADLRFITMAAQKFVDESKEFLAILNDFRTSLPERLPHVEPLSSAESPIRQEVS-----LVSAQ------YKDLLNRVNALQDRVSGLGGRQREYQDALDKANEWLRSVHPRVSRIISEPIAGDPKGVQDQMNEAKALHNELLSSGRLVDNAQQALDNLLRSLGGQLSPME-INQLELPIADLKNNYQQLLDNLGEHCKTLDKTLVQSQGVQDALDSLVGWVNQAEDKFKMNLRPASLIKERLQEQIREHKVLLADLQSHQASIDSVQVSAKHLLASASNARIAKKVESNLNDVTVKF-EKLYEKANKRGEFLDDVYNRLSRYLDEISTVEQRMASLQEALDSRETSLLSTEELARRMNELSRDKDQLAPQFEDCVRSGKDLISLRDVTDTGVLRDRIKALESQWRNINISIDERAKLSKQKAEQQLAYEGLKDQVLSWLASTEARVNGLPPVAIDLDRIKQQHDELKPICKDYRDYAPTIDKINDIGAQYDALI-----------RPESPARKRSTYSPIKRTSPLRRMSGDARSPSPTKGGILSPLSTGSSGFGSRRSSQDGFQLS-ELSPVQQQLSEINNRYGLIGVRLNDRQHELDNLNEELRKQYENLKGLAQFLERIQRQLPKESVSNKDEAERCIKQARKILEDMYEKQSLLDT-TKAQVKDILRRKSDVPGAEQLRQENDSIQEKWKNLNDICKNRIAFSEKLRDFLDTHGNLKSWLDS----KERMLTVLGPISSDPRMVQSQVQQVQVLREEFRTQQPQLKHFQELGHDVVDHLAGT-PDAQAVEIKLKDILGKWDDLVGKLDDRANSLGGAADSSKEFDAAVNRLREALQNISDNLD----TLPTDGDHQENLRKIENLERQLEGQRPLLADVEQSAATLCNILGDPASRADVNSRVAALEKQYLALQKKLD 2652 HSP 4 Score: 84.3445 bits (207), Expect = 5.827e-15 Identity = 340/1861 (18.27%), Postives = 762/1861 (40.95%), Query Frame = 3 Query: 12783 IIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSE--------QKVDPLKKQLEE----LIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLD---------------AEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND---DSSIDESIKKLKIIINKVDGVFSENVSID---TKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFE---SAMKDLKLNIVDPY---QTRDIWEESLNLVKEVKSHEETLKNLD----QVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDI-----FVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNF----EQKINEMSDQINNDY-------SELEECKI---DFTNLLSAWNEQK-ESINSTIND----SKKLIRQA-PGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYD--LDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKL----AKISSSNKGLQSQTMEYKEKIMNLLSLANEF--WNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQR--LEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKR----FMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATH-LKYISQKHDIVL--IRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQ-SEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGS-IKHYINIIKSQWSDLLSWSEQRGLNLKDHL 18104 ++ +DDR NSL EF++ N L + L N S N+ +K++ L++QLE L D+ ++ +T+ + LG +++S + ++ Q ++ ++ +D K + + + SL + + F EN S+ L + +P++++ Q+++H + + R+ + L G DL T + ++ +LD + ++E L A ++ R ++ K + E L WL TAE LA+ T + ++E R+++ + +++ S E+ K L F + ID K ++ + DR+ + + L ++ D++ + +L E +A L DP + + I EE NL K ++S + K++ G D ++SE D A +++ L D+ + +++ +F N ++ + L L E + L+ R ++I++ + + V K+ + LD+L V E++ E+ D+ F + + +E ++ + K +G + + E+NL ++ L F Q ++++ D +++++ SEL++ + DF N + E+K E + ++ + L+R A G +++ ++++ + + + + ++LD A+ + +F + L WL +TEE + K + D + QE K L D++ + + G ++ + +I + D KR++ + + + R DLE+ + + ++K+ L+N + EK+ + + D L+D L K F D + + + + +++V + + + ++ A ++ S +GL+ + Y++ + + S+ E + + + +K E HL +L E++ G H ++ + G +L++ ++N +E ++ + L+R + + + + + L+ + E +L EW + L P+E P + + + D+ P ++ INQ+G QL + S + S + R N + +++ + ++ +L E +DE +EW + +L + + + L +H+ I D++ + V + + ++++E S + AT R L+ L++ + + + + LE AL + F Q ++ +D++ ++ PD Q + I P L+ + A ++ I + ++ D ++ ++ R+ LE A++ F + + L T +NQ P+S + I EQ+E + AL D+ ++ + + A + K D + I+ + +++ W V + + +R +LD A+ F +++ + E L P I++Q +E + + RR G L + D ++ + + +L W ++ +RE+ L DA+ + + + + NLL +L E K + G D++ V+ + + + ++ +E +N A+ L + S E ++ I + L+ + W + + E++++LE A +F+ N L + +K++ L Q P + +L+ ++ + ++ ++ ++ G +++ + E S + + + ++W LL + R L++ L Sbjct: 2541 LVGKLDDRANSLGGAADSSKEFDAAVN-------------RLREALQNISDNLDTLPTDGDHQENLRKIENLERQLEGQRPLLADV-EQSAATLCNILGDPASRADVNSRVAALEK--QYLA-LQKKLDTK---KAETEASLRDGRHFAENCSKTLGWLGGELSNLTDRLLVSAHKPTLQH-----QIDTHEPIYREVMAREHEVIMLINKGKDL---TDRQQDRGVKRDLDRIQQQWEKLRREAVDRHTRLQTCMEHCKKYSQTSETFLAWLRTAEDKLADL-TPGVLSKAKLETRLRDLQTFRSEVWKHSGEFENTKGL-------GETFLSSCDIDKEPIKAELQDIRDRWERLNNDLIARAHEIENCSRRLDDFNDELRNLDHSLGRCEDRLAAHDALGGAAKDPKLLERVKAIREELTNLSKPLQSLKALAKDISAEARAAGGDADHLTSEVDGLA--DRMSELQGRLDD-------RCGELQSAATAVSQF---NEQMKSLGIDLNDLETEIEKLSPP--GREIKIVQVQIDDVGKI----QTKLDRL--VGRLEDA-ERAADVLVDAGFAADTTQTREQISTLRK---TLGRLDNRVRDHEDNLHSTLKALREFYDHQSQTLDDIQD-VSDEFKRMKPVGSELDQIRRQQEDFRN----FRERKVEPLAINVDKVNVAGRDLVRSAGSGVSTTAIEKDLEKLNDRWNDLKERMNERDRRLDVALLQSGKFQEALAGLSKWLSDTEEMVANQKPPSSDYKVVKAQLQEQKFLKKMLLDRQNSMGSLANLGKEVANHCEPGERASIEKQLNDLMKRFDALTDGAEQRELDLEEAMEVAKRFHDKISPLELWLDNTERSVKAMELIPTDEEKIQQRIREHDR-LHDEILGKKPDFSD-----LADVTAQLMHLVSDEEAVNLGEKVRGVTERYTGLVDASDNIGALLAESRQGLRHLVLSYQDLVAWMESMEAELKRFKSVPVYAEKLLEQMDHLL----------------ELNENIAG----HASNVESTVESGAELMKHISN-DEAIQLKDKLDSLQRRYGDLTNRGGDLLKSAQNALPLVQQFHEAHNRLVEWMQSAEAAL-----APSE--PRQADVLRLEGELADMRPI---LDSINQVGPQLCQLSPGEGAATIESIVTRDNRRFDSIVEQIQRKAERLHLSNQRAKEVTGDIDELLEWFREMDTTLREADLPAMEPKLVRAQLQEHRSINDDISSQKGRVRDVTAASKKVLRESPQS-ENTATLREKLDDLKEIVDTVAQLCSERLGILEQALPLSEHFADSHQGLTAWLDDMEQQISRLSMPALRPDQITLQQDKNERLLQSIAEHKPLLDKLNKTGEALGALVADDDGAKINEILDTDN----ARYAALRLELRERQQALESALQESSQFSDKLEGMLRALANTVDQVNQLDPLSALPQKIREQIEDNDALMDDLDKRQDAFSAVQRAANDVIAKAGNKADPAVRDIKAKLEKLNNLWNDVQNATKKRGSSLDDILSVAEPFWKQLNSVMKTLKDLEETLSCQEPPAAQPQDIKKQQVALQEIRHEIDQTKPEVEQVRRHGSNLMNMCGEPDKPEVKKHIEDLDNAWDNITALYAKREENLIDAMEKAMEFHETLQNLLKFLTKAEDKFAHLGA-VGSDIDAVKRQIEQLKSFKDEVDPHMVEVEALNRQAVELTERTSPEQAASIREPLSVVNRRWEALLRGMVERQKQLEHALLHLGQFQHALNELLVWINKTDSTLDQLKPIPGD--PQLLEVELAKLKVLANDIQAHQNSVDTLNDAGRQLIETEKGSVEASTTQEKLRKLNNEWKQLLQKASDRQHELEEAL 4291
BLAST of Dystonin vs. Ensembl Zebrafish
Match: DST (dystonin [Source:HGNC Symbol;Acc:HGNC:1090]) HSP 1 Score: 810.061 bits (2091), Expect = 0.000e+0 Identity = 643/2340 (27.48%), Postives = 1177/2340 (50.30%), Query Frame = 3 Query: 12489 YLNSKHKAMDEC---KSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAE-----QKIETAEKS------MHKIDNLAAINEKIIESIDDRQNSL--ILQHKIVTEFESKKNDFIRKIDEANNDPEL-------AKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND----------DSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQK-SHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQ--VGERNMEILENETNSVEKLVCQARNDLDKLKSVDAF------ENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKL-QIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWND-LKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEA---TQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQD-SKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKT---PPL---IPIFDRS----KRMETNQGISKIQEPLFV---NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK---------------------------------------------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF 19163 +++ K D C +S++ Q ++RE +F +LD + DL LR + + IE ++ L+ N + +K+ +E S ++ L K+++ R+ + L H + EF SK +F + A E +++N ++ F + ++ L+ QL+EL +G G K+++ +++ V ++ L + V++ + L+ +F +LE+L ++ + + ++ PS E+ K+Q+ +LL L R+++++ + G + K ++ E++ L +++ LL AE ++ + + +++ F + EP WL EK LAN + T + ++E++I ++K L+ + S+ +S++ L + +K E V + +N F E Q+ + L N D+V L L + + D+ + P E L L ++++ ++ ++ G +L + ++ ++ I K++ + + EI+ + + ++ +A + ++ +L++ L + A E D T +GE+ E+ ++ V++L Q + LD L V + + E ++ + E+ +R++ + + ++ + + K++ E+ ++ ++ E K++ + D + ++L+ K +++ K++++ + + ++ ++ ++LK + + ++ ++ + QL+ A LA +F +++ L WL +T Q ++ + L + ++E++ + + KP +D + K+G L ++ + +G I E A + Y +K +K RA+ L++ I +T+ ++K+D LE I +R+ SV EK+ E++ + DL+KLQ + L Q G E + R DKD L+ + ++ L+++ + + +Q+ E + K+++++ LA +FW D LI +TI T +++L V+ +++ +E R EID ++++ + G +L+ P++ P ++++ +E+ +E + + ++++ ++ + ++ + + + +L + P+ T+ V QI++ KE K D ++E +N Q G L K + + ++ + + W L + RQH+L+ LL+LG+F A+DE + W+ TE L + GD ++E+ LA+H +++ D+ +++V + R ++++ SS G EA +LE L + W+ + E + L+ AL +A F+G+ +++ + + + +L K GGLPDTA+EQL +++ T + +E +I + + E+D+ L KW++V+ + RK +LE+A+ FH + FINWLT E+ L P S I+ TI+ Q++ H+ ++ SHR++++ LDK THLKY SQK D+VLI+NL+ S+ RWEKVV RS ER R LD K AK+F + L++ + + L+ + I P KI+ Q+T+HKEF LG + YD+T R G L+DK +QD ++K+D ++ L+ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + A L+ S +DSS+++ Q+ EL + W V L+ K+ RLE+A +QA EF + L E+ +++E LR P++E E + +I H F K L + ++ G IL +P++ +IKH+ IIK+++ ++ +W+ Q L LD L + LL+ LL WL AE TL + + L E K EH+ F+ +MT KQ D D++ K+K PP+ IP+ D+ KR T + + NP++N L SKW+QVW + L+RR++L D ++ L+E++ NF+F+ WR+RYM WMNH KSRVMDFFRR D D DG+VTR+EFIDGI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C +++ Q G KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCRV H G + S + AKGRTN ELREK P+GT MA F Sbjct: 1362 HMSISKKVDDACSSLESKLLGIGQFQNSIREMFASFADLDDELDGMAPVGRDLEILRDQKSAIEAFVAKLQDLTRNTSNGRDSCRKMLESEASPDLLGLRRDLETLGKQCGKLMDRATARKEQVEETLGH--LEEFYSKTQEFTSNLSTAERQEESQGSVGLETEVINQQLESFKVFQKDVIESLQSQLQELNTLGQALIQNAPKGTSTKNLDHDLEEVNSRWNTLNKKVAERSAQLHEALLHCGRFQDALESLLSWLTDTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLDDRKATVELIKTEGRKVTDLADTVDKEKIGREIECLGQRWDALLKKAENRHKQLENISVVAQQFHETLEPLTEWLTATEKRLANSEPIGTQTS-KLEEQISQHKALEEEVLGRGKVLYQAMSLGQSLRTLGCVDDK------ETVQVKLENTQRS----FLELQELCRQKDELLRQARANAQLFGEDEVALM-TWLDEVHAKLSDVSVQDYTPAVLEKQHAEQLALHEDIELRKQNIEQAILNGLELLKQTTGDEVVVIQGKLDGIKTRYSEINTMSSSVSKTLDKALSLATKLQSSHEELNVWLEKVEA---ELDMFTDPQPLGEQLTELQHRQSALVQQLKEQ-KPLLDALNEVSSALLELVPWRAREGLDRMITEDNERYRSASDALIQRVEQTRAAILKSQQFEQAAGAELQWFTDAEIKLSGLGDVSLEPEKTTAQLQAQKSFSMDIM----RHKDAVDDIVKTGEAIMNSKDEAEKQALKVKLQALLEKYTVVSQLNSERCLQLERAHSLACQFWETHDELWPWLQDTRATFTQLSQPAIEYEALRQQQEELRQMRELIAEHKPHIDKMNKTGPQLVEL-SPAEGTAIREKYETADRLYGQLKVDVKHRASTLDEAISKSTQFHDKIDPMLESLERISERLRQPPSISVEVEKIREQISENKALSVDLEKLQPSYETLKQRGEEMIA--RSQGADKD----------LSAKAVQDKLDQMVFLWTD---IQALLEEREAKLLDVMDLAEKFWCDHCALI------VTIKDTQELLKELEEPGVDPSVVKQQQESVEGFREEIDGLQEELNVVQNLGAELMTACGEPDK-PVIKKSIDEVNSAWETLNKTWKERVEILEEAMQAAVQFQDSLQNMFDSVDIMEGKLDSMSPVGTDLETVKQQIEELKEFKGDAYQLQIEMERLNHQAGLLLKKVMDEDDRTSISEPMNELKMLWENLDKKIINRQHKLEGALLALGQFQHALDELLTWLTHTEELLGEQRKACGDPKAIEIELAKHHVLQNDVLAHKSTVEAVNRAGCDLME---SSAGEEARGLQNKLENLNQRWKNILEKTEQRRQLLDSALLQAQGFHGEIEDMQRWLKDSERQLLASKAVGGLPDTAREQLNTHLELCSTLEVKEEIYKHLLERGQQILAMTPEGQDSTTELDLRNLQDKWESVQAKVKERKVKLEEALAMATDFHNSLQDFINWLTQAEQTLTMVSPASLILETIMFQIDEHKVFVTEVNSHRDQIMELDKTGTHLKYFSQKQDVVLIKNLLLSVQSRWEKVVQRSVERGRLLDDARKRAKQFHESWSKLMEWLEESERALDTELEIANDPDKIKTQLTQHKEFQKALGSKHSVYDTTSRTGRALKDKTSLQDDNQKLDHMLSELRDKWDTVCGKSVERQNKLEEALLFSGQFTDALQALIDWLYKVEPQLAED-QPVHGDIDLVLNLIDSHKVFQKELGKRTGSVQALKRSARDLIESSHDDSSWVKVQMQELSTRWETVCSLSVSKQTRLEQALSQAEEFHSTVHILLEWLAEAEQSLRFHGALPDDE--EALRALIEQHKEFMKRLEEKRLALSKATSMGEAILSICHPDSITTIKHWNTIIKARFEEVTAWARQHQQRLSSALDELQATQELLEKLLNWLQWAETTLGEKDKDPMPQELEEVKALIAEHQTFLEEMTRKQPDVDKVTKTHKRKATADPPVQSHIPVLDKGRTPRKRSPTQTMYTAAASQAQIETKNPRVNLLVSKWQQVWLLALDRRRKLNDALDRLEELKEFANFDFDVWRKRYMRWMNHKKSRVMDFFRRIDKDQDGKVTRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPLTDADKIEDEVTRQVAKCKCPKRFQVEQIGANKYRFYLGNQFGLVHCLHDPLIADETITNRDNQNLTPHLHVAVLESCILFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGSKMLRSESNSSITQSPIAKGRTNVELREKFILPEGTTQVMASF 3648
BLAST of Dystonin vs. Ensembl Zebrafish
Match: macf1a (microtubule actin crosslinking factor 1a [Source:ZFIN;Acc:ZDB-GENE-030131-3606]) HSP 1 Score: 786.949 bits (2031), Expect = 0.000e+0 Identity = 638/2467 (25.86%), Postives = 1204/2467 (48.80%), Query Frame = 3 Query: 12420 EPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSN--------------------LKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDF---IRKIDEANNDPELA----KLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFED----TLYGFESAMKDLKLNIVDPYQTRDIWEE---SLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALV--RENDSLTG-QVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWN----EQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLP---TETRPVLTQIQKTKELKNDIEPKHRDIELINQLG-YQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXX-XXXXXXQSIGKAI---EIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPI-QDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIP--IFDR--SKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFK------------------------------PATLPIPT-------------KKPTTA--KIPSPRVSQPL---SSPRIHQPVSSPRIPQPV-TSPRIS-----QNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQAS 19454 E E E++ + + SSL +L + + E +SR+ +R +L +++D+ D DSL Q + N + L N L+ E E L+ Q + AE+ +++ +IES ++R V EF ++ D + + +E N + +++ + A ++VD ++ +L+ + +G + + +E ++++ ++ L + V++ + L+ KF +LE L ++ + + ++ PS EY K+Q+ +LL L R+ +++ + G + + + ++Q +L L ++ NLL A + + + L+ F + EP WL E+ L++ + T + ++ ++I +K LQ + SS + ++ +L+ + + + + + D + L +R + H E + ++ +L L LF + L + L V YQ + ++ +L L +E+ S ++T+ + G+ L + ++ + I K++ + + + E++ + K L E ++ +A RF +++ ++ L + A + E D+ Q ++ ++ + E V V + + L L A E ++ + + +R+++ +T++ + + +++ EE +D + + E+K+ + S + + + A+N K++++ + + ++ +LK D + + E+ ++ + L++A L F +Y L+ WL ETE + Q +D + L + + +++ L S + KP +D ++K G L+++ + +G + +A++RY IKE +K+RAT L++ + + + ++K+D LE R+ + EK+ E+L +LDKL L C+ + + + ++ + + +++ + + +G K+ ++L LA +FW D+ + T+ + ++DL V+ + + E ++ E D +++ + G LI E P+V++ +E+ +E + + +++ +D + + ++ L F ++N + L +P T+ V QI++ K+ K ++ + D+E ++ G L K S ++ + L + W L+D + RQH+L+ LL+LG+F A+ E W+ T +L + D ++E+ LA+H ++R D+ +++V + +E+++ SS G E +L++L +SW+ L + LE AL++A F+G+ +E + + S+L K +GGLP+TA+EQL++ M++ + + ++ + + + G + ++ +L KW ++ E R+ +LE+A+ F + INWLT E+ LN +P S I+ T+L Q++ H+ ++ +HRE++L L+K + L++ S K D+VLI+NL+ S+ RW+K+V RS +R R+LD K AK+F + R L D + L+ + I P KI+ Q+ KHKEF +LG YD+T R G +RDKA + D++K+D ++ ++ KW ++C KS+ER+ L +ALL SG + +A+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + A LM +D+++++ QL EL + W+ V L+ K+ RL++A QA EF L E+ S++E LR + PEE E + ++ H F + + + +N G IL +P+ +IKH+I II++++ ++L+W++Q L+ L L LL++LL WL AE TL+ ++ L+ + + K EH+ F+ +MT KQ D D++ T + K+ P P + DR +++ + Q + NP++ QL S+W+QVW + L+R+++L D ++ L+E++ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+++EM VADIFD++ G+IDY +F+AAL P+++ Y +P + + I DEV +Q+++C C+ +++ Q G+ KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCRV C C A+GRTN ELREK P+G +A F+ + P+ PT KP A K P+P Q S H+ S+ ++ +P S R S P++ + RTP + P + SR +R +S++GS AS Sbjct: 2973 EKEFEEVTEKTEQCCSSLESRL-------QGVGEVQSRVRDVFSRLADLDDELDSLSPVGRDADSLASQADAVRGFLSRLNALRSELENHGGECTTMLRREGSSPDLLALRRETEALSRQAGKLAERGQNRL--------ALIESAEER----------VREFYARLADLQALLGRAEEVLNTQAVVGTEVEVIKQQLQEFKAVEREQVDSIQPKLQHVNAVGQGLIQSAAKHTDTQALEHDLETTNLHWNSLNKRVAERIAQLQEALLHCGKFQDALEPLLSWLSDTEELIANQKPPSAEYRVVKAQIQEQKLLQRLLDDRRGTVEMIRAEGERIAATAETQDRDKIQKQLQSLGERWTNLLEKASARQKQLEELQVLALQFHEAVEPLSEWLSATERRLSSAEPMGTQTS-KITQQIVRHKALQEEVSSRENNVDRLESLSQSLHPL---SCAADQ----DWLGERVGAVRSGHTELRDWCVRREAMLEQALANAQLFGEEEVEVLNWLAEVAQRLAEVSVQSYQPEHLEQQHKHTLALNEEIVSRKKTVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKSRYAEMTAGSSKALRTLEQALQLATRFASSHDDINQWLDRVEAELNNAEPDTTPAYQDRQKELKCVSAEKRLVLDTVNEVGSALLDLVPWRAREG----LDRLVADANQRYRQADETITQRVQLVQAAIQRSQQYEEAVDAELTWVGETERKLASL-----GPLSLEPDVTVAQLQVQRAFNIDIIRHKDTVDQLLKTREDILESCSEQQRDALKVKTDSLSARYEAVNQSHAERFSALEQAQVLVARFWETYEELEPWLGETETLITQLPPPAIDTEALRQQQDQMRLLRESIAEHKPHIDKLLKIGPQLAELSAQ-EGATVRQRYNEAERRYMRIKEEVKSRATALDEAVSQSVQFHDKMDPLLETLEGAVQRLRQPPPVAAEVEKIREQLAEHRATGLELDKLLPSFSAL------CARGEELISRAPHDDPAAQAVRSRLLRLRSLWDEIRQRAEEREG----------KLQDVLDLAGKFWADMAALLS-----TLRDSQDIVKDLEDPGVDPSLIKQQIEAAEAIKAETDGLREELEIVRTLGADLIFACGE-TEKPEVKKTIDEMNGAWEGLNRTWRERMERLDEAMTASVQYQDA---LQGMFDYLDNAVIKLCDMPAVGTDLSTVKQQIEELKQYKVEVYQQQIDMEKLSHQGELLLRKVSDQTDRDMIQEPLTELRHLWDNLVDKITVRQHKLEGALLALGQFQHALSELQSWLSHTHATLDTQRPISSDPKAIEIELAKHHVLRNDVLSHRSTVETVNSAGSELLE---SSPGDEINHLRDQLDELNRSWKNLLLKTDERQKLLEAALQQAEGFHGELEEFLQWLRRTESQLSAAKPTGGLPETAREQLQQHMELQAQLAQRGEHYHRLLDHGESILLARGGEDAGPGTTQTQQNLAMLQNKWASLNTKMEDRRGKLEEAVSLATGFQSSLQDTINWLTQAEQTLNMAQPPSLILDTVLFQIDEHKVFVNEVNTHREQVLALEKAGSQLRFASLKQDVVLIKNLLLSVQARWDKLVQRSLDRGRHLDEARKRAKQFHEAWRKLTDWLEEAESRLDSELEISNEPDKIKIQLAKHKEFQKSLGSKQPVYDTTVRSGKAMRDKATLPADTQKLDNLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFAEALQALVDWLYRVEPQLAED-QPVHGDLDLVSNLMDCHKVFQKELGKRTSSVQALKRSARELMETGRDDTAWVKVQLQELSNRWDTVCALSVSKQTRLQQALKQAEEFRTAVQMLLEWLSEAEQTLRFRGVLPEEA--ETLQALLHTHRDFMQTVEEKRVDVNKAAGMGEAILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHEQRLETALTELLNNAALLEELLSWLQWAETTLVQRDTEPLTQDILQLKTLITEHQVFMEEMTRKQPDVDKV-TKTYKRKPAEHPSSLSDRKGARKHQQQQQQHHSVQVTGGNPRLTQLCSRWQQVWLLALDRQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTSKLEMTAVADIFDRDCDGYIDYYEFVAALHPNKDAY--RPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVTVTPGYFC-CR----------ARGRTNLELREKFILPEGATQGLAAFRSRGRRSKPSSRTASPTRSSSSASHSAHSCASVPSAPATPTASSRSSQSQSRGYAKPWLAHSKTPTPTKCQSCPEHSQTPGHEGGSTTKLKRPTFHSSRGSLTGENGGTPTAAKPGRSETKRTPSSTSGPASRAGSRAGSRASSRRGSDAS 5351 HSP 2 Score: 235.728 bits (600), Expect = 1.409e-60 Identity = 114/228 (50.00%), Postives = 162/228 (71.05%), Query Frame = 3 Query: 402 ADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPK 1085 ADERD +QK+TF W+N HL+K+ K + D++ DLRDG L++LLEVLS L + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ +I S +S DL+ K+ LL WS++A E YP + NFS+SW DG+ F AL+H+ RPDLID++ +++ S ++NLE AF A+ LGV ++++ EDV DEKS++TYV+S+++ PK Sbjct: 22 ADERDRVQKKTFTKWVNKHLIKVRKHITDLYEDLRDGHNLISLLEVLSGVTLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISEIYVSGESGDLTAKEKLLIWSQQATEGYPGLRCTNFSSSWSDGRLFNALLHRYRPDLIDMQVVAQQSNRENLEQAFEIAES-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPK 248 HSP 3 Score: 96.6709 bits (239), Expect = 1.498e-18 Identity = 77/406 (18.97%), Postives = 185/406 (45.57%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDM--DFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILN 3026 W++E ++ + +DL + + + ++D ++ K E++ ++ + ++ + L+ ++ +L + S +S F+ E + W+ +E++++ + W D+ + ++ K+E++ ++ ELE ++ + L + NH A ++ A L+++WQWI L C++ HL+ Y QF ++ + ++ + +L + + ++ L E L ++ + E + +Y+ TV ++ ++SV L R+ ++AIC ++ +GE L +NS W+V + P++CF + + +A TA ++ + + LW + L ++ V L + + +W+ + P RQ+ ++ L+ Sbjct: 548 GWVEETQDLLERAEWGSDLPSVEQHLQDHHIIHTAVEDLLNSLKEARTYESRVSPNLRSSYSETLSKLENQYCKLLEHSSWRLRCLESLRAFVSHCTEELIWLNEREEEELAFDWSDS-NTNMAAKREQYADMRSELEEKQDVMRSLQDTADHLCLENHPAKQTVEAYSAALQTQWQWIKELCVCVEQHLKDNTAYFQFMSDSRDCESYLRQLQDTIKRQYTCDKNSRLGRLEDLLQDSMEEKEQLIEYRSTVASLVGRAKSVVQLRPRSADSNLGTTTPIRAICDYRQIEANSQITISKGEECVLEDNSQRTKWKVISPTGNEAMVPSVCFTVPPPNQEAIDTASRMEQMYQNVMSLWHQLHLNMKSVVSWHYLQKDIRNISSWSLDTMRLQPPAERQQALDNLD 952 HSP 4 Score: 54.6842 bits (130), Expect = 5.846e-6 Identity = 77/317 (24.29%), Postives = 144/317 (45.43%), Query Frame = 3 Query: 9441 SINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQP-------FLENVLM---NNASRNEPKLKELDDKIKQKLLVASNIEAKVND-TRKLLG---SFEVAVKSCGDWIALTTEL---LSDRMFVRLDN--------EKFKEKL---DEIKEGYEMKQRDMEQARKICKEL---VSQSNCKDQ-----NSIEICMENL-EKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLL-ALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQA 10277 + + L WL+E + + +G LS+DP +N Q++ +Q +L E +RQP E +L + SR+E L+E+ ++ ++I A+ +D T +L G + A + ++ L EL ++D + RLD E + +L EI+ E ++ + QA ++C EL V++ +D+ S+ ++NL E+ L++L LS + + + + +L++ + N N +S P D L L Q ED + I + S +I +E S++ P G ++ A Sbjct: 2445 AASQLGPWLREKELMMSVLGPLSIDPNMLNTQKQQVQFMLREFETRQPQFDQLTRAAEGILSLTGDERSRDEQDLEEVRREL-------ADISAQWDDLTSRLSGRSQQIDQAQGTSQHYLTLLRELSQSVAD-LGERLDAQASLSAQPEALRRRLQETGEIRSELEQRRGQLSQAEQLCTELSAIVAEPYLRDELHKRLESVSGPLKNLEERAADGLSQL----QAALSSTQQFQQMFDELRSWLDGNTGNQTTGMSETLPCQPDALKTLLTQQEDFQRAIAQQRGSYELIQ------AEGASLLASLPAGDERLA 2743
BLAST of Dystonin vs. Ensembl Zebrafish
Match: macf1a (microtubule actin crosslinking factor 1a [Source:ZFIN;Acc:ZDB-GENE-030131-3606]) HSP 1 Score: 781.556 bits (2017), Expect = 0.000e+0 Identity = 635/2467 (25.74%), Postives = 1201/2467 (48.68%), Query Frame = 3 Query: 12420 EPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSN--------------------LKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDF---IRKIDEANNDPELA----KLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFED----TLYGFESAMKDLKLNIVDPYQTRDIWEE---SLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALV--RENDSLTG-QVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWN----EQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLP---TETRPVLTQIQKTKELKNDIEPKHRDIELINQLG-YQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXX-XXXXXXQSIGKAI---EIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPI-QDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIP--IFDR--SKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFK------------------------------PATLPIPT-------------KKPTTA--KIPSPRVSQPL---SSPRIHQPVSSPRIPQPV-TSPRIS-----QNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQAS 19454 E E E++ + + SSL +L + + E +SR+ +R +L +++D+ D DSL Q + N + L N L+ E E L+ Q + AE+ +++ +IES ++R V EF ++ D + + +E N + +++ + A ++VD ++ +L+ + +G + + +E ++++ ++ L + V++ + L+ KF +LE L ++ + + ++ PS EY K+Q+ +LL L R+ +++ + G + + + ++Q +L L ++ NLL A + + + L+ F + EP WL E+ L++ + T + ++ ++I +K LQ + SS + ++ +L+ + + + + + D + L +R + H E + ++ +L L LF + L + L V YQ + ++ +L L +E+ S ++T+ + G+ L + ++ + I K++ + + + E++ + K L E ++ +A RF +++ ++ L + A + E D+ Q ++ ++ + E V V + + L L A E ++ + + +R+++ +T++ + + +++ EE +D + + E+K+ + S + + + A+N K++++ + + ++ +LK D + + E+ ++ + L++A L F +Y L+ WL ETE + Q +D + L + + +++ L S + KP +D ++K G L+++ + +G + +A++RY IKE +K+RAT L++ + + + ++K+D LE R+ + EK+ E+L +LDKL L C+ + + + ++ + + +++ + + +G K+ ++L LA +FW D+ + T+ + ++DL V+ + + E ++ E D +++ + G LI E P+V++ +E+ +E + + +++ +D + + ++ L F ++N + L +P T+ V QI++ K+ K ++ + D+E ++ G L K S ++ + L + W L+D + RQH+L+ LL+LG+F A+ E W+ T +L + D ++E+ LA+H ++R D+ +++V + +E+++ SS G E +L++L +SW+ L + LE AL++A F+G+ +E + + S+L K +GGLP+TA+EQL++ M++ + + ++ + + + G + ++ +L KW ++ E R+ +LE+A+ F + INWLT E+ LN +P S I+ T+L Q++ H+ ++ +HRE++L L+K + L++ S K D+VLI+NL+ S+ RW+K+V RS +R R+LD K AK+F + R L D + L+ + I P KI+ Q+ KHKEF +LG YD+T R G +RDKA + D++K+D ++ ++ KW ++C KS+ER+ L +ALL SG + +A+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + A LM +D+++++ QL EL + W+ V L+ K+ RL++A QA EF L E+ S++E LR + PEE E + ++ H F + + + +N G IL +P+ +IKH+I II++++ ++L+W++Q L+ L L LL++LL WL AE TL+ ++ L+ + + K EH+ F+ +MT KQ D D++ T + K+ P P + DR +++ + Q + NP++ QL S+W+QVW + L+R+++L D ++ L+E++ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+++EM VADIFD++ G+IDY +F+AAL P+++ Y +P + + I DEV +Q+++C C+ +++ Q G+ KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR A+GRTN ELREK P+G +A F+ + P+ PT KP A K P+P Q S H+ S+ ++ +P S R S P++ + RTP + P + SR +R +S++GS AS Sbjct: 3341 EKEFEEVTEKTEQCCSSLESRL-------QGVGEVQSRVRDVFSRLADLDDELDSLSPVGRDADSLASQADAVRGFLSRLNALRSELENHGGECTTMLRREGSSPDLLALRRETEALSRQAGKLAERGQNRL--------ALIESAEER----------VREFYARLADLQALLGRAEEVLNTQAVVGTEVEVIKQQLQEFKAVEREQVDSIQPKLQHVNAVGQGLIQSAAKHTDTQALEHDLETTNLHWNSLNKRVAERIAQLQEALLHCGKFQDALEPLLSWLSDTEELIANQKPPSAEYRVVKAQIQEQKLLQRLLDDRRGTVEMIRAEGERIAATAETQDRDKIQKQLQSLGERWTNLLEKASARQKQLEELQVLALQFHEAVEPLSEWLSATERRLSSAEPMGTQTS-KITQQIVRHKALQEEVSSRENNVDRLESLSQSLHPL---SCAADQ----DWLGERVGAVRSGHTELRDWCVRREAMLEQALANAQLFGEEEVEVLNWLAEVAQRLAEVSVQSYQPEHLEQQHKHTLALNEEIVSRKKTVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKSRYAEMTAGSSKALRTLEQALQLATRFASSHDDINQWLDRVEAELNNAEPDTTPAYQDRQKELKCVSAEKRLVLDTVNEVGSALLDLVPWRAREG----LDRLVADANQRYRQADETITQRVQLVQAAIQRSQQYEEAVDAELTWVGETERKLASL-----GPLSLEPDVTVAQLQVQRAFNIDIIRHKDTVDQLLKTREDILESCSEQQRDALKVKTDSLSARYEAVNQSHAERFSALEQAQVLVARFWETYEELEPWLGETETLITQLPPPAIDTEALRQQQDQMRLLRESIAEHKPHIDKLLKIGPQLAELSAQ-EGATVRQRYNEAERRYMRIKEEVKSRATALDEAVSQSVQFHDKMDPLLETLEGAVQRLRQPPPVAAEVEKIREQLAEHRATGLELDKLLPSFSAL------CARGEELISRAPHDDPAAQAVRSRLLRLRSLWDEIRQRAEEREG----------KLQDVLDLAGKFWADMAALLS-----TLRDSQDIVKDLEDPGVDPSLIKQQIEAAEAIKAETDGLREELEIVRTLGADLIFACGE-TEKPEVKKTIDEMNGAWEGLNRTWRERMERLDEAMTASVQYQDA---LQGMFDYLDNAVIKLCDMPAVGTDLSTVKQQIEELKQYKVEVYQQQIDMEKLSHQGELLLRKVSDQTDRDMIQEPLTELRHLWDNLVDKITVRQHKLEGALLALGQFQHALSELQSWLSHTHATLDTQRPISSDPKAIEIELAKHHVLRNDVLSHRSTVETVNSAGSELLE---SSPGDEINHLRDQLDELNRSWKNLLLKTDERQKLLEAALQQAEGFHGELEEFLQWLRRTESQLSAAKPTGGLPETAREQLQQHMELQAQLAQRGEHYHRLLDHGESILLARGGEDAGPGTTQTQQNLAMLQNKWASLNTKMEDRRGKLEEAVSLATGFQSSLQDTINWLTQAEQTLNMAQPPSLILDTVLFQIDEHKVFVNEVNTHREQVLALEKAGSQLRFASLKQDVVLIKNLLLSVQARWDKLVQRSLDRGRHLDEARKRAKQFHEAWRKLTDWLEEAESRLDSELEISNEPDKIKIQLAKHKEFQKSLGSKQPVYDTTVRSGKAMRDKATLPADTQKLDNLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFAEALQALVDWLYRVEPQLAED-QPVHGDLDLVSNLMDCHKVFQKELGKRTSSVQALKRSARELMETGRDDTAWVKVQLQELSNRWDTVCALSVSKQTRLQQALKQAEEFRTAVQMLLEWLSEAEQTLRFRGVLPEEA--ETLQALLHTHRDFMQTVEEKRVDVNKAAGMGEAILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHEQRLETALTELLNNAALLEELLSWLQWAETTLVQRDTEPLTQDILQLKTLITEHQVFMEEMTRKQPDVDKV-TKTYKRKPAEHPSSLSDRKGARKHQQQQQQHHSVQVTGGNPRLTQLCSRWQQVWLLALDRQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTSKLEMTAVADIFDRDCDGYIDYYEFVAALHPNKDAY--RPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------ARGRTNLELREKFILPEGATQGLAAFRSRGRRSKPSSRTASPTRSSSSASHSAHSCASVPSAPATPTASSRSSQSQSRGYAKPWLAHSKTPTPTKCQSCPEHSQTPGHEGGSTTKLKRPTFHSSRGSLTGENGGTPTAAKPGRSETKRTPSSTSGPASRAGSRAGSRASSRRGSDAS 5708 HSP 2 Score: 251.906 bits (642), Expect = 1.706e-65 Identity = 121/239 (50.63%), Postives = 171/239 (71.55%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPK 1085 LDP +R V+RVADERD +QK+TF W+N HL+K+ K + D++ DLRDG L++LLEVLS L + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ +I S +S DL+ K+ LL WS++A E YP + NFS+SW DG+ F AL+H+ RPDLID++ +++ S ++NLE AF A+ LGV ++++ EDV DEKS++TYV+S+++ PK Sbjct: 63 LDPAERAVVRVADERDRVQKKTFTKWVNKHLIKVRKHITDLYEDLRDGHNLISLLEVLSGVTLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISEIYVSGESGDLTAKEKLLIWSQQATEGYPGLRCTNFSSSWSDGRLFNALLHRYRPDLIDMQVVAQQSNRENLEQAFEIAES-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPK 300 HSP 3 Score: 95.1301 bits (235), Expect = 4.430e-18 Identity = 77/406 (18.97%), Postives = 186/406 (45.81%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDM--DFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILN 3026 W++E ++ + +DL + + + ++D ++ K E++ ++ + ++ + L+ ++ +L + S +S F+ E + W+ +E++++ + W D+ + ++ K+E++ ++ ELE ++ + L + NH A ++ A L+++WQWI L C++ HL+ Y QF ++ + ++ + +L + + ++ L E L ++ + E + +Y+ TV ++ ++SV L R+ ++AIC ++ ++ GE L +NS W+V + P++CF + + +A TA ++ + + LW + L ++ V L + + +W+ + P RQ+ ++ L+ Sbjct: 600 GWVEETQDLLERAEWGSDLPSVEQHLQDHHIIHTAVEDLLNSLKEARTYESRVSPNLRSSYSETLSKLENQYCKLLEHSSWRLRCLESLRAFVSHCTEELIWLNEREEEELAFDWSDS-NTNMAAKREQYADMRSELEEKQDVMRSLQDTADHLCLENHPAKQTVEAYSAALQTQWQWIKELCVCVEQHLKDNTAYFQFMSDSRDCESYLRQLQDTIKRQYTCDKNSRLGRLEDLLQDSMEEKEQLIEYRSTVASLVGRAKSVVQLRPRSADSNLGTTTPIRAICDYRQIEITISK----GEECVLEDNSQRTKWKVISPTGNEAMVPSVCFTVPPPNQEAIDTASRMEQMYQNVMSLWHQLHLNMKSVVSWHYLQKDIRNISSWSLDTMRLQPPAERQQALDNLD 1000 HSP 4 Score: 54.6842 bits (130), Expect = 5.621e-6 Identity = 77/317 (24.29%), Postives = 144/317 (45.43%), Query Frame = 3 Query: 9441 SINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQP-------FLENVLM---NNASRNEPKLKELDDKIKQKLLVASNIEAKVND-TRKLLG---SFEVAVKSCGDWIALTTEL---LSDRMFVRLDN--------EKFKEKL---DEIKEGYEMKQRDMEQARKICKEL---VSQSNCKDQ-----NSIEICMENL-EKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLL-ALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQA 10277 + + L WL+E + + +G LS+DP +N Q++ +Q +L E +RQP E +L + SR+E L+E+ ++ ++I A+ +D T +L G + A + ++ L EL ++D + RLD E + +L EI+ E ++ + QA ++C EL V++ +D+ S+ ++NL E+ L++L LS + + + + +L++ + N N +S P D L L Q ED + I + S +I +E S++ P G ++ A Sbjct: 2813 AASQLGPWLREKELMMSVLGPLSIDPNMLNTQKQQVQFMLREFETRQPQFDQLTRAAEGILSLTGDERSRDEQDLEEVRREL-------ADISAQWDDLTSRLSGRSQQIDQAQGTSQHYLTLLRELSQSVAD-LGERLDAQASLSAQPEALRRRLQETGEIRSELEQRRGQLSQAEQLCTELSAIVAEPYLRDELHKRLESVSGPLKNLEERAADGLSQL----QAALSSTQQFQQMFDELRSWLDGNTGNQTTGMSETLPCQPDALKTLLTQQEDFQRAIAQQRGSYELIQ------AEGASLLASLPAGDERLA 3111
BLAST of Dystonin vs. Ensembl Zebrafish
Match: plecb (plectin b [Source:ZFIN;Acc:ZDB-GENE-100917-2]) HSP 1 Score: 353.214 bits (905), Expect = 4.319e-96 Identity = 259/927 (27.94%), Postives = 452/927 (48.76%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI----YQFR-NQYADLYANLNSALEELNDDFDHNDFRIDFNQTR-LENNYL----TYLKQYES----FCHLFDDISKVDRNNENQ--RKFHTIST--LWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMN-----EYLASISKELCDCENQINNMIISVQELKRDG--YPADQHYRIIININGKIDKVKKKF------EKLSPPTLSSGVISNRQYTPIHSMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLD----------GLNKIYEKFSTTFNEIKDSVDEFKMILESENKY-----QMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFI--EGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLRE----QVLLSTMDLVKNWTPEDFCNLEP 2993 LDP +R +LR+ADERD +QK+TF W+N HL+K + V D++ DLRDG L++LLEVLS + L + RFH L+N+ LDFLR + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +SDD+S K+ LL WS++ ++ Y I +NF+TSW+DGK F A+IHK P LID+ + + + +NLE AF A+KELGV ++++PEDV DEKS++TYV+SL++ P+ D+++ + R +Y L L + F+ F + + L +L T L ES LF + + + +H I W + E+ +L E ++++R ++I + +E ++ + ES +L+T + +N ++ + ++L + I + VQ LK DG A+Q YR + ++ ++ ++ + + + IS + + EL D V W++E I + DL GL++ E F + DE ++ S+ Y ++D+ + + N K++ L F++ + + + W+ KE++++++ W + + + K++ + L+ ELE+RE +N+ A G L + H ++ A L+++W WIL L C++THL+ Y QFF + EAD + ++ + + ++ E L ++ + E + ++K + + ++SV L R + ++ ++A+C DF + +G+ L NNS W+V N + P+ICFL+ ++ +A ++ L++ LW K LR Q L+ + L+++W F ++P Sbjct: 53 LDPAERAILRIADERDRVQKKTFTKWVNKHLIKTQRHVNDLYEDLRDGHNLISLLEVLSGETLPRERGRMRFHKLQNVQIALDFLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVNGQSDDMSAKEKLLFWSQRMVDGYHGIRCDNFTTSWRDGKLFNAIIHKHEPRLIDMPKVYRQTNMENLEQAFTVAEKELGVTRLLDPEDVDVPHPDEKSIITYVSSLYDAMPRVPDVQDGAKTNELELRWQEYYQLVTVLQQWIRHHVLIFEERRFPSSYEEVEILWRQFLKFKETELPPKESDKGRSKQLFQSFESAVQAGQIKVPPGYHPIDVEKEWGRLHVAILERERLLRIEFERLERLQQIVSKVQMESGVCEEQLNQTES--------LLQTDIRLLNAGKPAQHTVEVERDLDKADGMIRLLFNDVQMLK-DGRHLQAEQMYRRVYRLHERLVNLRSDYNLRLKSTATAATHTTVTSISQKSVQRVRP-EL-DEVTLRYAQDLLAWVEENQRRIDTAEWGIDLPTVESQLGSHRGLHQTIEDFRAKIERAR--ADENQLSPASKGTYREYLGKLDLQYTKLLNTSKSRLRNL-----------DQLYNFVNAATKELMWLNDKEEEEVNYDWSERNA-NMGAKKDNYSGLMRELELREKKVNDIQATGDRLIKDGHPGKKTVEAFTAGLQTQWSWILQLCCCIETHLKENTAYFQFFADVKEADERLKKMQDTMKKKYMCDRSTTATRLEDLLQDAVEEREQVNEFKNDIANLNKRAKSVIQLKPRDPTCPFRGKLPIQAVC------DFKQMEITMHKGDECALINNSQPSRWKVLNRSGDEAVVPSICFLVPPVNKEAVESVSGLEAGHQQTVILWQKLHADLRALLSWQYLMKDIQLIRSWNITMFKTMKP 948
BLAST of Dystonin vs. Ensembl Zebrafish
Match: pleca (plectin a [Source:ZFIN;Acc:ZDB-GENE-030131-8984]) HSP 1 Score: 350.903 bits (899), Expect = 2.237e-95 Identity = 260/937 (27.75%), Postives = 460/937 (49.09%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI----YQFR-NQYADLYANLNSALEELNDDFDHNDFR-------------IDFNQTRL------ENNYLTYLKQYESFCHLFDDISKVDRNNENQRKFHTIST--LWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIE---CATLTNKVEE-IESKIRKISY--PMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDG--YPADQHYRIIININGKIDKVKKKFEKLSPPTLSSGV-----------------ISNRQYTPIHSMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLD----------GLNKIYEKFSTTFNEIKDSVDEFKMILESENKY-----QMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFI--EGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLRE----QVLLSTMDLVKNW 2963 LDP +R V+R+ADERD +QK+TF W+N HL+K + + D++ DLRDG L++LLEVLS + L + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +SDD++ K+ LL WS++ +E Y + +NF+TSW+DG+ F A+IHK RP+LID+ + + + +NLE AF+ A+++LGV ++++PEDV DEKS++TYV+S++++ P+ D+ + + + R +Y +L L + F+ F + F +T L +N K +E KV N +H I W + E+ +L +E ++++R ++I + +E C N+VE +++ IR +S P+ ++ + I +L EN I + VQ LK DG A+Q YR + ++ ++ ++ +F L SGV + Q +P D V + +W++E I + DL GL++ E+F + + DE ++ S+ Y ++D+ + + KT+ L F+ + + + W+ KE++++++ W D S ++ K++ + L+ +LE RE +N G L + H A I+ A L+++W WIL L C++THL+ Y QFF + EA++ + ++ + + ++ + + E L ++ + E + ++K + + ++++ L R + + ++ V+A+C DF + +G+ L NNS W+V +S P+ICF++ + +A + LD L LW K + ++ Q L+ + L+ +W Sbjct: 212 LDPAERAVIRIADERDRVQKKTFTKWVNKHLVKAQRHITDLYEDLRDGHNLISLLEVLSGETLPREKGRMRFHKLQNVQIALDFLKHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVNGQSDDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHKHRPNLIDINKVYRQTNLENLEQAFSIAERDLGVTRLLDPEDVDVPHPDEKSIITYVSSMYDVMPRVPDVRDGVKANELELRWQEYYELVTMLLQWIRHHVIVFEERKFPSSYEEIEVLWRQFLKFKETELPAKETDKNRSKLIYKSFEGAVQAGQ--VKVPPN------YHPIDVEKEWGRLHVAILEREKLLRSEFERLERLQRIVSKVQMESGVCEEQLNQVETLLQTDIRLLSAGKPI---------QHASDIETDLNKAENMIRYLFNDVQLLK-DGRHLQAEQMYRRVYRLHERLVNLRSEFN----LRLKSGVTLSQVPMTQVPMTQISHVQTLQQSPQRVRPDLDEVTLKYIQDLLSWVEENQRRIEGAEWGEDLPSVESQLGSHRGLHQSIEEFKYKIDRAR--ADENQLTPVSKGAYREYLGKLDLQYAKLLTSSKTRLRSL-----------DQLHAFVVAATKELMWLNEKEEEEVNYDWSDRNS-NMTAKKDNYSGLMRDLEQREKRVNNVQMTGDKLLKDGHPARKTIEAFTAALQTQWSWILQLCCCIETHLKENTAYFQFFSDVKEAEDRMKKMEDTMKKKYVCDRSITVTRLEDLLQDAVEEKEQLNEFKTHLEGLNRRAKTIIQLKPRNPAQPIKGKLPVQAVC------DFKQMEITVHKGDECALVNNSQPYKWKVRDSSGNEAVVPSICFIVPPTNKEAVDVSSGLDGSQQRLMVLWQKLHVDMKSLLSWQYLMRDITLINSW 1106
BLAST of Dystonin vs. Ensembl Xenopus
Match: MACF1 (microtubule actin crosslinking factor 1 [Source:NCBI gene;Acc:100127846]) HSP 1 Score: 810.831 bits (2093), Expect = 0.000e+0 Identity = 661/2466 (26.80%), Postives = 1218/2466 (49.39%), Query Frame = 3 Query: 12372 LIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKS--------MHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLN---NTSK----NIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINK----LFDRFSEYQK-SHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERN----MEILENETNSVEKLVCQARNDLDKLKSVDAFENSL------EKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMS------DQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHP---EKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDK--KKLIE---DLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLG-YQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQ-DSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPL--IPIFDRSKRMETNQGISKI----QEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK-----FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF-----KFKPAT---------------LPIPTKKPTTAKIPSPRVSQPLSSPRIHQ-------PVSSP---------RIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSR 19472 LIA + Q S V+ + + + ++ + ++++ + + + +K + + + S + + +L +++D+ D+DSL+ Q + ++L +LKS +E+ + + EK M ++ L K+ E +RQ L+ + V EF K + +I A L ++ +T K N F +++VD L+ +L ++ IG + +E + + + ++ L + V++ + L+ KF +LE L ++ + + ++ PS EY K+Q+ +LL L R+++++ + G + ++ ++L+ L ++ LL A+ + + + + L+K F + EP WL EK LAN + T +++++IQ +K L+ D + + + + NK+ G + S + ++++ L R+SE Q + L N D+V + + L E + + + P ++ ++ + L +++ + + KN+DQ G+ L + ++ + I K++ + + EI+ S+ K L E ++ +A +F +++L L R D L+ G+ + + + ++K + R LD + V + L E ++ + + ++++ + + + ++ +I + +++ E+ D + ++ ++K+ + DQ + +D K+SI+ I+ ++++ L+ + + E + + +L+ A L +F +Y L W+ E + Q +D + L + ++E++ L S + KP +D ++K G LS++ N +G + A+K Y IKE ++ RA L+D + + ++K+ LE++ R+ P + P EK+ E + + +L+KLQ L+ E SR D D + ++ +KL ++ + ++++ E + K +++L LA +FW D+ + TI T+ + DL + ++ K+ IE ++ E D +++ I G LI E P+V+++ +E+ +E ++ + ++I + S + ++ + +W +L + P+ T+ V QI++ KE K ++ + ++E +N G L K ++ + L + W L + + RQ +L+ LL+LG+F A+ E + W+ T L + GD +E+ LA+H +++ D+ Q++V + + E+++ SS G +A+ RLE L + WE + + + +L+ AL++A F G+ ++ + + S+L K +GGLP+TA+EQL+ M+++ +++ + + G E ++ IL +KW + N E RK++LE+A+ F + FINWLT E++LN S I+ T+L Q++ H+ ++ HRE ++ LDK+ LK++SQK D+VLI+NL+ S+ RWEKVV RS ER R+LD K AK+F + + L+D + L+ + I P KI+ Q++KHKEF LG YD+T R G L++KA + D +K+D ++ ++ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + A L+ S ED+++++ QL EL + W+ V KL+ K+ RLE+A QA EF + L E+ S++E LR P++ E + ++I H F + + ++ +N G EIL +P+ +IKH+I II++++ ++L+W Q L+ L L LLD+LL W+ AE TL+ + + + K +EH+ F+ +MT KQ D D + K+KT D+++R + Q + + +P NP+INQL ++W+QVW + L R+++L D ++ L+E++ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF TTR+EM VADIFD++ G+IDY +F+AAL P+++ Y +P + + I DEV +Q+++C C+ +++ Q G+ KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCRV H G+ + S+SS+ A+GRTN ELREK P+G M PF + KP++ T P++ P+ P R ++ S+P P P +P + + V S +S T S + P + S+ GS+A +R SR Sbjct: 4457 LIADVPQDSDVSHLVYQAQ--QVQHDFEIVKEDVNECCANMETKLQGIGQFHSHVREMFSELADLDDELDSMGPVGRDIDSLKSQAEVIQKFL-------EALLSLKSSIESSECKCRDMLEKEGGPDLIVLMRELGTLNKQCSKLTERGKNRQGQLVATLRRVEEFNMKLKELNHQIVTAEGSSVLQGVVGTEVDTIKQQLDNFKVFQKEQVDSLQAKLHQVNGIGQGLIQSADKNCDVHGLEHDTEELNIKWNTLNKKVAERVTQLQEALLHCGKFQDALEPLLSWLTDTEDLIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRRTTVEMIQAEGVRIAEGADPADGDKISHQLEILAERWSLLLQKAQSRQKQLEDILVLAKQFHETTEPIFDWLSATEKKLANSEPIGTQTG-KIQQQIQRHKSLEGDITVHETDVHQ----ANKLGGSLAALCSNAEQERLSQKLEFLQARYSEVQDLCSRKGTLLGQALINARLFGEDEVEVL-NWLGDVEDRLNSVCVKDYKPEVLQNQHKQHMALNEDIINRK---KNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYSEITASSGKALKTLEQALQLAGKFQATHDELT------GWLRRAEDELSQSFGQSPSGDMIPQFQQQQKELKKEAMEYRIVLDTINEVGSALLELVPWRAREGLDKLVADANEQYRSISDTIGQRVDQIDAAIQRSQQYEQAADAELAWVAETKRKLLALGSICLEQDQTTAQLQVQKAFSVDIIR-------HKDSIDELISTEEEILATCGDEQKSVLQEKTKNLVQHYEDISHLNSERYARLERAQVLVGQFWETYEELIPWIDEMQVLFSQLPPPAVDHEMLRQQQEEMRQLRESVAEHKPHIDKLLKIGPHLSEL-NPEEGTAVQEKYRSAEKLYVGIKEEVRKRAMVLDDALAQAAQFHDKIGPMLETLESMASRL---RMPPLIPAEVEKIRECISENKNAVMELEKLQPAFQALKHRGEELI-SRSQGPDIDPAA-------------KDIQDKLDQLVFFWEDIKARADERESKFLDVLELAEKFWLDMNTL-----LTTIKDTHEIVHDLESPGIDPSMIKQQIEAADSIKEETDGLHEELEFIRILGADLIFACGE-TEKPEVKKSIDEMNTAWENLKRTWAERIEKLRDAMSHAVQYQDSLQAMFDWLDNTVIKLCDMPPVGTDISTVKEQIEEMKEFKVEVYQQQIEMEKLNHQGELMLKKAIDDTDRDIIQGPLTELKHLWENLGEKIAHRQQKLEDSLLALGQFQHALAELMSWLTHTNELLNAQRPICGDPKVIEVELAKHHVLKNDVLAHQSTVQIVNKAGNELLE---SSAGDDASSLRTRLETLNQLWEIVLQKTEEREQQLDMALQQAQGFSGEIEDFIQWQTNIESQLSAAKPTGGLPETAREQLQAHMELFAEIKANEDLYRHLLDKGQLMLISRDDATGSITEQNVSILKRKWQAISNKVEERKAKLEEALTLATDFQNSLQDFINWLTQAEQSLNIAPSPSLILDTVLFQIDEHKVFVNEVNIHREHIIELDKIGNQLKFLSQKQDVVLIKNLLLSVQSRWEKVVQRSVERGRSLDDARKRAKQFHEAWKKLIDWLEEAENHLDSELEISNDPDKIKLQLSKHKEFQKTLGSKQPVYDTTVRTGRALKEKALLSGDVQKLDHLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAE-DQPLHGDLDLVMNLMDAHKVFQKELGKRTSSVQALKRSARELLESSREDTTWVKVQLQELSTRWDTVCKLSVSKQTRLEQALKQAEEFHAAVHMLLEWLSEAEQTLRFRGALPDD--AESLQSLIDIHKEFMRKVEEKQIDVNTAVSMGEEILTMCHPDCITTIKHWITIIRARFEEVLTWGNQHQQRLQTALSELLANSELLDELLSWIQWAETTLIQRGQDPMPQNIDQVKALISEHQVFMEEMTQKQPDVDRVTKTYKRKTTDTNHASFNDKTRRKHSVQNATPVLPVLSQPETKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELKEFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTRLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAY--RPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRVVFLQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHPGN-KLKRTDSISSI----ARGRTNLELREKFILPEGVSQGMTPFRSRGRRSKPSSRTASPTRSSSSASQSNHSCTSVPSSPATPASGSKTPQHLSRCYEKPWLVNSKASTPIRCAEYPDFHTPSPEVTPAQGSKLKKAAVHTSRSS-LTGDTPTSSSAKSGRADPKKSASRAGSRAGSRASSR 6853 HSP 2 Score: 227.254 bits (578), Expect = 8.469e-58 Identity = 121/279 (43.37%), Postives = 169/279 (60.57%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAIS--------------------------------RFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI 1109 LDP +R V+RVADERD +QK+TF W+N HL+K+ K + D++ DLRDG L++LLEVLS +L + S RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI S +S D+S K+ LL W++K Y I NFS+ W DGK F A+IH+ RPDL+D++ + ++NLE AF A+ LGV ++++ EDV DEKS++TYV+S+++ PK + E I Sbjct: 56 LDPAERAVVRVADERDRVQKKTFTKWVNKHLIKVRKHINDLYEDLRDGHNLISLLEVLSGIRLDPEAPRSLRLSRLPSRRLLLMREDLEEDPDDAPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYVSGESGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNAIIHRYRPDLVDMQKVELQGNRENLEQAFEIAES-LGVTRLLDSEDVDVASPDEKSVITYVSSIYDAFPKVPEGAEGI 333 HSP 3 Score: 98.9821 bits (245), Expect = 4.330e-19 Identity = 82/368 (22.28%), Postives = 169/368 (45.92%), Query Frame = 3 Query: 1932 IKDSVDEFKMILESENKYQMDMD------FHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKE-------TVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEG--ELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLS------TMDLVKNWTPE 2972 + SV+E L Y++ M + ++ + L+T++ +L S + +S +F+ ++ I W+ KE++++ + W D ++ K+E F L+ ELE ++ I L++ NH A ++ A + S+WQW+ L C++ HL+ Y QFF + E++ + L + + ++ D +NR + D+L+ D KE +V ++ S+++ L R + + +KA+C D+ + G E L +N+ W+V ++ P++CFLI + +A + A ++ + + LW +L + + L+S +++V++W E Sbjct: 647 VHTSVEELTSSLREARSYEVKMSHNFRSSYSETLSKLETQYCKLRETSSSRLHNLQSLHDFVSQATAQIIWLNQKEEEELAYDWSDGNP-NIAAKKEYFTELMQELEEKQDVIQALQETAELLSLENHPAKQTVEAYSAAVVSQWQWVKQLCLCVEQHLKENTAYFQFFNDVRESEVYLNNLQDSIKRKY------SCDRTTSINR-LEDILQDSMDEKEQLIQSRSSVASLVGRSKNIVQLKPRNPELTLANTLPIKAVC------DYRQIEITIGRNEECVLEDNTQRTKWKVISTTGNEAMVPSVCFLIPPPNQEAMEMASRVEQLYQKVMSLW--HQLHINTKSLISWNYLRKDVEVVQSWNAE 998 HSP 4 Score: 74.3294 bits (181), Expect = 1.073e-11 Identity = 217/1096 (19.80%), Postives = 445/1096 (40.60%), Query Frame = 3 Query: 14382 RFKEVLNEVTKKATKIGSN---RTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKS-AVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILAN-IEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFH--EMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQ---IQKTKE----LKNDIEP---KHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRAD-MNISQASVSKMERKAAEIIKE-----DVSSLGHEATQRLEQLRKSWEELKEHARAKHFEL----------EDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQ--LKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRF-EDMNRTL--LDDIASNL-EILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDS-SKRCGGDM 17549 ++KEVL +T K + G N + Q + + Q ++ S ++ +++ ++ + N LSA + + D + LK ++ AVDRV + L A+ +++F ++ L+ WL E + ++ + ++L QE + S ++I+ G L + K L N + + K +N + + R L+D + + V+ LE+ + + + ++ P +L+ +L + D+DK + ++ + A+ ++ EI D +L R K N +I + + L +++ ++E + L L + F N K +E H E+ L N S+ ++ ++ L +I ++ K++ + LI V ++ + ++++ +FE V+ + N++ + I + ++ ++++ L +GP+ + + +Q IQK E LK+ IE K RD+ L K P++ + L +N ++L + RQ QL L + EF+ + E I+ E S + ++++++ L K+ + + ++ QA + ++ +I+ DV L H+ E+L W L + + +L +DAL+ L + D +++ N ++ ++ K +EQ L+R +D RT ++ E I++ + + G I +EIL ++W + A++R+ +LE + + FH +WL+ TEK L P+ I +Q++ H++L+ DIT H ++ +K+ L + + + + + R+ +V S + L A+ F ED L L D+ L + +D P ++ Q +H + ++ D + G L + ++ I E + ++ ++ + S + K L AL L+G ++ L WLR E +LS S + GDM Sbjct: 4068 QYKEVLQRLTDKIKQAGKNLAAQPAVSTQPDAVKQQLQETSGIRSELEQLAKEVTDAQK--------LCNELSAL-----VMEPYLKDELQKRLDTVALPLKGMEDLAVDRVNR---------------LQTALSSSQQFQQMFDELRSWLDEKQLQHVKSHPVSAKLEKLQIQLQEQEEFQKSLSQYSGSYEMIVAEGESLLMSAQPGEEKTTLQNQLVNLKSNWNELGKQSSERHGKLKDCLQKAQKYVRHVEDMVPWLEDCEIHMKE-MEITLDPVQLEAQLLRAKALQTDIDKKRSLLEMM----------NSAADLLIEAAEIDDRDILEERAKIN-----QRIDAITEELHNKSGSFEEMSLRLKELKDSFSNIDKKMEGAKHLLEIFTALGPQACSSKNLESMRSQQDMLLGLDSQI-LYLKNL------IQGLIADVPQDSDVSHLVYQAQQVQHDFEIVKEDVNECCANMETKLQGIGQFHSHVREMFSELADLDDELDSMGPVGRDIDSLKSQAEVIQKFLEALLSLKSSIESSECKCRDM---------LEKEGGPDLIVLMRE-LGTLNKQCSKLTERGKNRQGQLVATLRRVEEFNMKLKELNHQIVTAEGSSVLQGVVGTEVDTIKQQLDNFKVFQKEQVDSLQAKLHQVNGIGQGLIQSADKNCDVHGLEHDT----EELNIKWNTLNKKVAERVTQLQEALLHCGKFQDALEPLLSWLTDTEDLIANQKPPSAEYKVVKAQ------IQEQKLLQRLLDDRRTTVEM------IQAEGVRIAEGADPADGDKISHQLEILAERWSLLLQKAQSRQKQLEDILVLAKQFHETTEPIFDWLSATEKKLANSEPIGTQTGKIQQQIQRHKSLEGDITVHETDVHQANKLGGSLAALCSNAEQERLSQKLEFLQARYSEVQDLCSRKGTLLGQALINARLFGEDEVEVLNWLGDVEDRLNSVCVKDYK----PEVLQNQHKQHMALNEDIINRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYSEITASSGKALKTLEQALQLAGKFQATHDELTGWLRRAEDELSQSFGQSPSGDM 5082
BLAST of Dystonin vs. Ensembl Xenopus
Match: MACF1 (microtubule actin crosslinking factor 1 [Source:NCBI gene;Acc:100127846]) HSP 1 Score: 804.283 bits (2076), Expect = 0.000e+0 Identity = 652/2438 (26.74%), Postives = 1208/2438 (49.55%), Query Frame = 3 Query: 12372 LIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKS--------MHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLN---NTSK----NIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINK----LFDRFSEYQK-SHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERN----MEILENETNSVEKLVCQARNDLDKLKSVDAFENSL------EKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMS------DQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHP---EKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDK--KKLIE---DLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLG-YQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQ-DSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPL--IPIFDRSKRMETNQGISKI----QEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK-----FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF-----KFKPAT---------LPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQAS 19454 LIA + Q S V+ + + + ++ + ++++ + + + +K + + + S + + +L +++D+ D+DSL+ Q + ++L +LKS +E+ + + EK M ++ L K+ E +RQ L+ + V EF K + +I A L ++ +T K N F +++VD L+ +L ++ IG + +E + + + ++ L + V++ + L+ KF +LE L ++ + + ++ PS EY K+Q+ +LL L R+++++ + G + ++ ++L+ L ++ LL A+ + + + + L+K F + EP WL EK LAN + T +++++IQ +K L+ D + + + + NK+ G + S + ++++ L R+SE Q + L N D+V + + L E + + + P ++ ++ + L +++ + + KN+DQ G+ L + ++ + I K++ + + EI+ S+ K L E ++ +A +F +++L L R D L+ G+ + + + ++K + R LD + V + L E ++ + + ++++ + + + ++ +I + +++ E+ D + ++ ++K+ + DQ + +D K+SI+ I+ ++++ L+ + + E + + +L+ A L +F +Y L W+ E + Q +D + L + ++E++ L S + KP +D ++K G LS++ N +G + A+K Y IKE ++ RA L+D + + ++K+ LE++ R+ P + P EK+ E + + +L+KLQ L+ E SR D D + ++ +KL ++ + ++++ E + K +++L LA +FW D+ + TI T+ + DL + ++ K+ IE ++ E D +++ I G LI E P+V+++ +E+ +E ++ + ++I + S + ++ + +W +L + P+ T+ V QI++ KE K ++ + ++E +N G L K ++ + L + W L + + RQ +L+ LL+LG+F A+ E + W+ T L + GD +E+ LA+H +++ D+ Q++V + + E+++ SS G +A+ RLE L + WE + + + +L+ AL++A F G+ ++ + + S+L K +GGLP+TA+EQL+ M+++ +++ + + G E ++ IL +KW + N E RK++LE+A+ F + FINWLT E++LN S I+ T+L Q++ H+ ++ HRE ++ LDK+ LK++SQK D+VLI+NL+ S+ RWEKVV RS ER R+LD K AK+F + + L+D + L+ + I P KI+ Q++KHKEF LG YD+T R G L++KA + D +K+D ++ ++ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + A L+ S ED+++++ QL EL + W+ V KL+ K+ RLE+A QA EF + L E+ S++E LR P++ E + ++I H F + + ++ +N G EIL +P+ +IKH+I II++++ ++L+W Q L+ L L LLD+LL W+ AE TL+ + + + K +EH+ F+ +MT KQ D D + K+KT D+++R + Q + + +P NP+INQL ++W+QVW + L R+++L D ++ L+E++ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF TTR+EM VADIFD++ G+IDY +F+AAL P+++ Y +P + + I DEV +Q+++C C+ +++ Q G+ KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR A+GRTN ELREK P+G M PF + KP++ + +PS + P S ++ Q + + ++ + P+S ++S PK AS + SR +R +S++GS AS Sbjct: 4763 LIADVPQDSDVSHLVYQAQ--QVQHDFEIVKEDVNECCANMETKLQGIGQFHSHVREMFSELADLDDELDSMGPVGRDIDSLKSQAEVIQKFL-------EALLSLKSSIESSECKCRDMLEKEGGPDLIVLMRELGTLNKQCSKLTERGKNRQGQLVATLRRVEEFNMKLKELNHQIVTAEGSSVLQGVVGTEVDTIKQQLDNFKVFQKEQVDSLQAKLHQVNGIGQGLIQSADKNCDVHGLEHDTEELNIKWNTLNKKVAERVTQLQEALLHCGKFQDALEPLLSWLTDTEDLIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRRTTVEMIQAEGVRIAEGADPADGDKISHQLEILAERWSLLLQKAQSRQKQLEDILVLAKQFHETTEPIFDWLSATEKKLANSEPIGTQTG-KIQQQIQRHKSLEGDITVHETDVHQ----ANKLGGSLAALCSNAEQERLSQKLEFLQARYSEVQDLCSRKGTLLGQALINARLFGEDEVEVL-NWLGDVEDRLNSVCVKDYKPEVLQNQHKQHMALNEDIINRK---KNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYSEITASSGKALKTLEQALQLAGKFQATHDELT------GWLRRAEDELSQSFGQSPSGDMIPQFQQQQKELKKEAMEYRIVLDTINEVGSALLELVPWRAREGLDKLVADANEQYRSISDTIGQRVDQIDAAIQRSQQYEQAADAELAWVAETKRKLLALGSICLEQDQTTAQLQVQKAFSVDIIR-------HKDSIDELISTEEEILATCGDEQKSVLQEKTKNLVQHYEDISHLNSERYARLERAQVLVGQFWETYEELIPWIDEMQVLFSQLPPPAVDHEMLRQQQEEMRQLRESVAEHKPHIDKLLKIGPHLSEL-NPEEGTAVQEKYRSAEKLYVGIKEEVRKRAMVLDDALAQAAQFHDKIGPMLETLESMASRL---RMPPLIPAEVEKIRECISENKNAVMELEKLQPAFQALKHRGEELI-SRSQGPDIDPAA-------------KDIQDKLDQLVFFWEDIKARADERESKFLDVLELAEKFWLDMNTL-----LTTIKDTHEIVHDLESPGIDPSMIKQQIEAADSIKEETDGLHEELEFIRILGADLIFACGE-TEKPEVKKSIDEMNTAWENLKRTWAERIEKLRDAMSHAVQYQDSLQAMFDWLDNTVIKLCDMPPVGTDISTVKEQIEEMKEFKVEVYQQQIEMEKLNHQGELMLKKAIDDTDRDIIQGPLTELKHLWENLGEKIAHRQQKLEDSLLALGQFQHALAELMSWLTHTNELLNAQRPICGDPKVIEVELAKHHVLKNDVLAHQSTVQIVNKAGNELLE---SSAGDDASSLRTRLETLNQLWEIVLQKTEEREQQLDMALQQAQGFSGEIEDFIQWQTNIESQLSAAKPTGGLPETAREQLQAHMELFAEIKANEDLYRHLLDKGQLMLISRDDATGSITEQNVSILKRKWQAISNKVEERKAKLEEALTLATDFQNSLQDFINWLTQAEQSLNIAPSPSLILDTVLFQIDEHKVFVNEVNIHREHIIELDKIGNQLKFLSQKQDVVLIKNLLLSVQSRWEKVVQRSVERGRSLDDARKRAKQFHEAWKKLIDWLEEAENHLDSELEISNDPDKIKLQLSKHKEFQKTLGSKQPVYDTTVRTGRALKEKALLSGDVQKLDHLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAE-DQPLHGDLDLVMNLMDAHKVFQKELGKRTSSVQALKRSARELLESSREDTTWVKVQLQELSTRWDTVCKLSVSKQTRLEQALKQAEEFHAAVHMLLEWLSEAEQTLRFRGALPDD--AESLQSLIDIHKEFMRKVEEKQIDVNTAVSMGEEILTMCHPDCITTIKHWITIIRARFEEVLTWGNQHQQRLQTALSELLANSELLDELLSWIQWAETTLIQRGQDPMPQNIDQVKALISEHQVFMEEMTQKQPDVDRVTKTYKRKTTDTNHASFNDKTRRKHSVQNATPVLPVLSQPETKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELKEFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTRLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAY--RPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRVVFLQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------ARGRTNLELREKFILPEGVSQGMTPFRSRGRRSKPSSRTASPTRSSSSASQSNHSCTSVPSSPAT-PASGSKVTQGSKLKKAAVHTSRSSLTGDTPTSSSAKS--GRADPKKSAS---RAGSRAGSRASSRRGSDAS 7109 HSP 2 Score: 224.942 bits (572), Expect = 4.141e-57 Identity = 112/235 (47.66%), Postives = 158/235 (67.23%), Query Frame = 3 Query: 405 DERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI 1109 DERD +QK+TF W+N HL+K+ K + D++ DLRDG L++LLEVLS +L + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI S +S D+S K+ LL W++K Y I NFS+ W DGK F A+IH+ RPDL+D++ + ++NLE AF A+ LGV ++++ EDV DEKS++TYV+S+++ PK + E I Sbjct: 22 DERDRVQKKTFTKWVNKHLIKVRKHINDLYEDLRDGHNLISLLEVLSGIRLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYVSGESGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNAIIHRYRPDLVDMQKVELQGNRENLEQAFEIAES-LGVTRLLDSEDVDVASPDEKSVITYVSSIYDAFPKVPEGAEGI 255 HSP 3 Score: 98.9821 bits (245), Expect = 4.488e-19 Identity = 82/368 (22.28%), Postives = 169/368 (45.92%), Query Frame = 3 Query: 1932 IKDSVDEFKMILESENKYQMDMD------FHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKE-------TVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEG--ELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLS------TMDLVKNWTPE 2972 + SV+E L Y++ M + ++ + L+T++ +L S + +S +F+ ++ I W+ KE++++ + W D ++ K+E F L+ ELE ++ I L++ NH A ++ A + S+WQW+ L C++ HL+ Y QFF + E++ + L + + ++ D +NR + D+L+ D KE +V ++ S+++ L R + + +KA+C D+ + G E L +N+ W+V ++ P++CFLI + +A + A ++ + + LW +L + + L+S +++V++W E Sbjct: 569 VHTSVEELTSSLREARSYEVKMSHNFRSSYSETLSKLETQYCKLRETSSSRLHNLQSLHDFVSQATAQIIWLNQKEEEELAYDWSDGNP-NIAAKKEYFTELMQELEEKQDVIQALQETAELLSLENHPAKQTVEAYSAAVVSQWQWVKQLCLCVEQHLKENTAYFQFFNDVRESEVYLNNLQDSIKRKY------SCDRTTSINR-LEDILQDSMDEKEQLIQSRSSVASLVGRSKNIVQLKPRNPELTLANTLPIKAVC------DYRQIEITIGRNEECVLEDNTQRTKWKVISTTGNEAMVPSVCFLIPPPNQEAMEMASRVEQLYQKVMSLW--HQLHINTKSLISWNYLRKDVEVVQSWNAE 920
BLAST of Dystonin vs. Ensembl Xenopus
Match: rab11fip2 (RAB11 family interacting protein 2 (class I) [Source:Xenbase;Acc:XB-GENE-5947669]) HSP 1 Score: 795.808 bits (2054), Expect = 0.000e+0 Identity = 525/1576 (33.31%), Postives = 867/1576 (55.01%), Query Frame = 3 Query: 14754 QLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDS-KKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPL-----IPIFDRS----KRMETNQGI-SKIQEPLFV-NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKY-------KFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGD--CECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVS------SPRIPQPVTSPRISQNIPSSRVSQSLASPRTP 19373 QL+ A+ L +F +Y L WL+ETE + Q + LD D L + +++I+ L + KP +D + K+G L + +G I A Y+ IKE +K RA L++ I + + ++K+D L+ I +R+ S EK+ E+L + +L+KLQ + L+ E +R DKD S ++ +KL ++ + +Q+ T E + +++++L LA +FW D + F + T I +L+ V+ ++++ E ++ EID + ++ + G +LI P++ P V + +EL ++ + + ++++ +D + ++ L +W ++ + P+ T+ V QI + K+ K D + ++E +N Q L K + N K V L+ + W L D + RQH+L+ LL+LG F A+DE W+ TE L K GD ++E+ LA+H +++ D+ +++V +++ ++I+ SS G EA+ RLE L + W+ + + + L+ AL +A F+ + +++ + + ++ +L K GGLP+TA+EQL +++ F ++ +++S ++ ++ + I+ D+ L +KW++V RK++LE+A+E FH + FINWLT E+ L P S I+ T+L Q++ H+ ++ SHR++++ LDK THLKY SQK D+V+I+NL+ S+ RWE VV RS ER R LD K +K+F + L++ + + L+ + I P KI+ Q+TKHKEF LG + YD+T R G L++KA + D +K+D+++ ++ KW ++C KSIER+ L +ALL+SG + DA+ L+ WL IEP+L++ + GD++ V L++ H + +K+L R I+ + A L+ S +DSS+++ Q+ EL + W V L+ K+ RLEEA +QA F ++L E+ + +E LR I P++E + + +I H F + + ++N G IL +P++ +IKH+I II++++ ++L+W++Q L LD L +K LL+ LL WL +E TL + ++ L E K EH+ F+ +MT KQ D D++ K+K IP+ D+ KR T S Q L NP++N L SKW+QVW + L RR++L D ++ L+E+ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFI+GI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C+ +++ Q G+ KY KFGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCRV H G + S+++ L+ AKGRTN ELREK P+G +M PF+ P + +++ SP S SSP I S +P+ P +T + +S+ S SP +P Sbjct: 4729 QLERAVSLVNQFWETYEELWPWLIETENAISQLPVPALDYDTLKQQQEDIRQLRELIAEHKPHIDKMNKTGPQLLDLSPE-EGFFIQEKYVSADTLYSEIKEVVKKRAIYLDEAISQSAQFHDKIDPTLENLQRIAERLRQPPSISAECEKIKEQLSENKNVSVELEKLQPVYETLKKRGEEMI-ARSEGADKDISAKVVQ-------------DKLDQMVFVWEDIQALTEEREAQLLDVLELAEKFWCDHYALIATFKD-----TQDLIRELDGPGVDPSVVKEQQETAEVIKEEIDGFQDELDAVISLGSELISACGEPDK-PVVNKNIDELTSAWDTLNKTWKERVEKLDEAMQAAVQYQDGLQALYDWVDIATLKVESMPPIGTDLVTVKQQIVELKQFKTDTYQQQIELERLNHQKELLLKKVTDENDKQAVEDPLSELKLLWNSLEDKIINRQHKLEGALLALGPFQHALDELTTWMTHTEGLLNEQKSVGGDPKAIEIELAKHHVLQNDVLAHKSTVETVKKAGNDLIE---SSAGEEASSLNSRLESLNQRWQIILDKTEKRMKLLDSALFQAQGFHSEIEDMHQWLTDIERQLLASKPVGGLPETAREQLSAHLELCSLFEVKEEIYKRLMQKSQQMMERCTDDPEANIDQDVINLKEKWESVDTKLSERKAKLEEALEVATGFHNSLQDFINWLTQAEQTLTIASPPSLILDTVLFQIDEHKVFVTEVNSHRDQIMELDKTGTHLKYFSQKQDVVIIKNLLISVQSRWENVVQRSLERGRMLDDARKRSKQFHEAFDKLMEWLEESERSLDSELEIANDPDKIKTQLTKHKEFQKTLGGKHTVYDTTTRSGRSLKEKATLTDDIQKLDDMLSEIRDKWDTVCGKSIERQNKLEEALLISGQFTDALQALIDWLYRIEPQLAED-QPVHGDIDIVMNLIDNHKVFQKELGKRSSSIQALKRSARELIEGSRDDSSWVKAQMQELGTRWETVCNLSVSKQTRLEEALHQAESFHAAVHALLEWLADAEQALRFHGILPDDE--DSLRLLIEQHKEFMRRVEEKRSELNKGASMGEAILAICHPDSITTIKHWITIIRARFEEVLTWTKQHQQRLAVALDDLIAKKELLESLLAWLQWSEMTLNEKDKEDIPQDLDEVKALIEEHQIFMEEMTQKQPDVDKVTKTYKRKVESTTGQSQIPVLDKGRGGWKRSPTPSLYPSGTQTSLETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIEGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPITDADKIEDEVTRQVAKCKCAKRFQVEQIGENKYRVISLLFKFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGSKMLRSESNSSITTQPLI-AKGRTNVELREKFMLPEGASQSMTPFR------PKGRRSRPSSRGASPNRSN--SSPNIQASPSLAASSITPKTPLHLTRNYGKPWLANSKTSTPCKSPESP 6266 HSP 2 Score: 241.506 bits (615), Expect = 3.737e-62 Identity = 131/280 (46.79%), Postives = 175/280 (62.50%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKL--------------------FTQN-------------AISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI 1109 LDP +R VLR+ADERD +QK+TF WIN HLMK+ K V D++ DLRDG L++LLEVLS L + Q+ RFH L+N+ LD+L+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +S+D+S K+ LL WS++ E Y I ENF+T W+DG+ F A+IHK RPDLIDL +++ S NLE AF A+K LGV ++++PEDV DEKS++TYVAS+++ PK D E I Sbjct: 194 LDPAERAVLRIADERDKVQKKTFTKWINQHLMKVRKHVSDLYEDLRDGHNLISLLEVLSGDTLPRERDFLKTLRLVSSSEACEYDQHEDVEDEDKGPREKGRMRFHRLQNVQIALDYLKKRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKEKLLLWSQQTSEGYGGIRCENFTTCWRDGRLFNAIIHKYRPDLIDLDTVAVQSNITNLENAFYVAEK-LGVTRLLDPEDVDVSSPDEKSVITYVASMYDAFPKTPDGGEGI 472 HSP 3 Score: 101.293 bits (251), Expect = 7.313e-20 Identity = 89/460 (19.35%), Postives = 208/460 (45.22%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDL---DGLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSN 3182 +WI+E + + +DL +G + ++ F E + S+ E KM E + ++ +S L++++++L + + F+ ++ + W+ KE++++ + W + + K++ +L+ EL+ +E I + + + NH A + I+ A ++++W WIL L HC++ H+ + Y ++F +A +A + L + + ++ L + E L +E + E + YK TV ++ ++++ L R + + ++AIC K+ + + E + L +NS W+V + P++CF + + +A +A ++ + + LW + + ++ V L++ ++ ++ L P Q+++ L + + D + + I ++I + +N C + EL S+ Q ++ N Sbjct: 821 SWIEEMQVQLDRAEWGSDLSSIEGHLENHKNFDRAVEEFESSLKEAKMS-EPQITGIFKANYDESLYKLESQYSKLLNSSRNRQKHLDTLHSFVSRATRELIWLNEKEEEEVAYDWSERNQ-NIPAKRDYHGDLMRELDHKEEIIKSVQDIAEQMLLQNHPARSTIEAYRAAMQTQWNWILQLCHCVEQHIRQNSAYFEYFNDAKDAAEYLKSLKDAILRKYSCDKSTSLHKLEDLLQESMEEKEQLLQYKSTVGSLVGKAKAIIQLKPRNPDNPLKASIPIRAICDYKQ---IEITIYKDDECI-LASNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDSANRIEQMYQSVLTLWHESHINMKSTVSWHYLMNEIEGIRASKVSTIKTLLPGEHQQVLSNLKSRFDEFLEDSQESKIFSMSDIAQLEREVNVCKLYYEELLKSAEREEQEESIYN 1274 HSP 4 Score: 91.2781 bits (225), Expect = 8.087e-17 Identity = 200/1025 (19.51%), Postives = 452/1025 (44.10%), Query Frame = 3 Query: 10767 VPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMS--PTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESEN----------LSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMI------GKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQI-----LQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDI----NNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKH-YPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPXXXXXXXXXXXXXXXXXXXXESXXXXXXXXXXXXXXXXXXXQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQ---------------PIDVS-KLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNA------TLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAE--QKIETAEKSMHKID---NLAAINEKIIESIDDRQNSLILQHKIVTEFE------SKKNDFIRKIDEANNDPELAKL----LNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESI 13646 P + K LD+++ + + A + + + + +F + ++ + KE M +VLGP+ + Q QQV L+ E + + ++ R+ GQ I+ P+S EV ++E L ++ K ++L L DR I + S ++ + +S++L+ + + TN++ S + + +L + K + K+ N L + L ++++ E+ ++ + + +++ K + V+ + ++ HH ED + W+Q K ++ N E I L NI + I +Q +K + S E + E + ++ K+ + +L++L + E I+ + NNL Q+A+ + N I+ WI+ +HK+++ V L +I+S + ++ K+++ + + L + ES L + + + E K + Q+ +N++ + L K T+ +E+ + + +KQ P S K + ++T Q + ++P ++ ++ S+AQ V+A T L + E + ++ ++ + +K +L +K + + ++ I ++ L +++D+ DL+ L+ Q D++ K LS+L + EN + +K+ E S I +L A+N++ + +D ++ I++ E + D ++ ++E + +N+ AF +++++PL+ +++E+ +G + + +E +++ V ++ L V+ + L+ +F +LE+L ++ + + +++ PS E+ K+QL +LL L R+ +++ + + G + + + K ++ +L L +++ LL AE +N + D + +++ F D EP WL + EK LA + T A ++ ++I + K L++D ++ ++S+ Sbjct: 3388 APESSKWKEMLDKIDSLWQDINKMAAERQQTLEESSNDLNQFQTAEAQLKQWLTEKELMASVLGPLSIDPNMLKTQKQQVQILLKEFDARKQQYEQFRSAGQRILNRPCELPSSGEV--VKEQLASVACKWESLTGQLNDRCDRIEQAIVKSTNYQNNLKGLSEKLSAMSNTL---STNMVVSSHPDAVNQKLQTAKQLQKDLSNEKKNIEDTKVLCQELSNLVAEDYLKAELNRQMDTVVKPFVDLEEKAGYHVEQLQMAFASSQKFHHLS------EDLKSWIQTKTKEQN----EAAPISANL--NILESLITEQAEVQNALKDQLSTYEKVTAEAENLLQKTKGDEKAN-LQSQLSMLKSNWEAINKQVLERQNNLLDCQQKATKHKEFVEN----IQPWIEECQHKLSEFTVSVDLSAIESSVGQVKVLQKNVDKQRGMMETLNS----------------------ATESLLNCCQTDKEAIREQNKNMNSQVDELIDNLHIKRDTLEKFGTRLKEFQESVKDTEKQLAVAQEHLDAHNSLGPQGCSNKHLTIMQTQQKVLQNLEPQID----IVRSLAQQLVVDAFDAEGVTELVLQAESLHQKHHIIHQEVEEKCSFLETKLQGIGHFQNSIREMFSQFTELDDELDSMTPVGRDLNILQCQKQDISKFL-------KKLSDLITTNENANKTCKKMLATESSPDLIGIKRDLEALNKQCNKLLDRAKSREEQTENIISRTEDFYCTLKQFFDLLKGVEEHEESQGAVGMETDVINHQLNIFMAFQKEEIEPLQARIQEVNQLGQGLVQSAAKNTSTESLEHDLEEVNVRWNTLNNKVAQRAAQLQEALLHSGRFQDALESLLSWLTDTEDLVASQKPPSAEFKVVKAQLQEQKLLQRLLSDRKPTVEAIKREGEKIASSADQTDKEKILKQLSTLERRWDELLKKAEIRNRQLDDILVVAEQFHDSLEPLSEWLTSTEKKLAISEPIGTQTA-KLLQQISQQKALEDDITAHNKSL 4356
BLAST of Dystonin vs. Ensembl Xenopus
Match: rab11fip2 (RAB11 family interacting protein 2 (class I) [Source:Xenbase;Acc:XB-GENE-5947669]) HSP 1 Score: 795.423 bits (2053), Expect = 0.000e+0 Identity = 529/1596 (33.15%), Postives = 874/1596 (54.76%), Query Frame = 3 Query: 14754 QLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDS-KKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPL-----IPIFDRS----KRMETNQGI-SKIQEPLFV-NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKY-------KFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGD--CECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVS------SPRIPQPVTSPRISQNIPSSRVSQSLASPRTP-----KVVASPGLQRKSRIP 19418 QL+ A+ L +F +Y L WL+ETE + Q + LD D L + +++I+ L + KP +D + K+G L + +G I A Y+ IKE +K RA L++ I + + ++K+D L+ I +R+ S EK+ E+L + +L+KLQ + L+ E +R DKD S ++ +KL ++ + +Q+ T E + +++++L LA +FW D + F + T I +L+ V+ ++++ E ++ EID + ++ + G +LI P++ P V + +EL ++ + + ++++ +D + ++ L +W ++ + P+ T+ V QI + K+ K D + ++E +N Q L K + N K V L+ + W L D + RQH+L+ LL+LG F A+DE W+ TE L K GD ++E+ LA+H +++ D+ +++V +++ ++I+ SS G EA+ RLE L + W+ + + + L+ AL +A F+ + +++ + + ++ +L K GGLP+TA+EQL +++ F ++ +++S ++ ++ + I+ D+ L +KW++V RK++LE+A+E FH + FINWLT E+ L P S I+ T+L Q++ H+ ++ SHR++++ LDK THLKY SQK D+V+I+NL+ S+ RWE VV RS ER R LD K +K+F + L++ + + L+ + I P KI+ Q+TKHKEF LG + YD+T R G L++KA + D +K+D+++ ++ KW ++C KSIER+ L +ALL+SG + DA+ L+ WL IEP+L++ + GD++ V L++ H + +K+L R I+ + A L+ S +DSS+++ Q+ EL + W V L+ K+ RLEEA +QA F ++L E+ + +E LR I P++E + + +I H F + + ++N G IL +P++ +IKH+I II++++ ++L+W++Q L LD L +K LL+ LL WL +E TL + ++ L E K EH+ F+ +MT KQ D D++ K+K IP+ D+ KR T S Q L NP++N L SKW+QVW + L RR++L D ++ L+E+ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFI+GI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C+ +++ Q G+ KY KFGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCRV H G + S+++ L+ AKGRTN ELREK P+G +M PF+ P + +++ SP S SSP I S +P+ P +T + +S+ S SP +P + +P K R+P Sbjct: 4528 QLERAVSLVNQFWETYEELWPWLIETENAISQLPVPALDYDTLKQQQEDIRQLRELIAEHKPHIDKMNKTGPQLLDLSPE-EGFFIQEKYVSADTLYSEIKEVVKKRAIYLDEAISQSAQFHDKIDPTLENLQRIAERLRQPPSISAECEKIKEQLSENKNVSVELEKLQPVYETLKKRGEEMI-ARSEGADKDISAKVVQ-------------DKLDQMVFVWEDIQALTEEREAQLLDVLELAEKFWCDHYALIATFKD-----TQDLIRELDGPGVDPSVVKEQQETAEVIKEEIDGFQDELDAVISLGSELISACGEPDK-PVVNKNIDELTSAWDTLNKTWKERVEKLDEAMQAAVQYQDGLQALYDWVDIATLKVESMPPIGTDLVTVKQQIVELKQFKTDTYQQQIELERLNHQKELLLKKVTDENDKQAVEDPLSELKLLWNSLEDKIINRQHKLEGALLALGPFQHALDELTTWMTHTEGLLNEQKSVGGDPKAIEIELAKHHVLQNDVLAHKSTVETVKKAGNDLIE---SSAGEEASSLNSRLESLNQRWQIILDKTEKRMKLLDSALFQAQGFHSEIEDMHQWLTDIERQLLASKPVGGLPETAREQLSAHLELCSLFEVKEEIYKRLMQKSQQMMERCTDDPEANIDQDVINLKEKWESVDTKLSERKAKLEEALEVATGFHNSLQDFINWLTQAEQTLTIASPPSLILDTVLFQIDEHKVFVTEVNSHRDQIMELDKTGTHLKYFSQKQDVVIIKNLLISVQSRWENVVQRSLERGRMLDDARKRSKQFHEAFDKLMEWLEESERSLDSELEIANDPDKIKTQLTKHKEFQKTLGGKHTVYDTTTRSGRSLKEKATLTDDIQKLDDMLSEIRDKWDTVCGKSIERQNKLEEALLISGQFTDALQALIDWLYRIEPQLAED-QPVHGDIDIVMNLIDNHKVFQKELGKRSSSIQALKRSARELIEGSRDDSSWVKAQMQELGTRWETVCNLSVSKQTRLEEALHQAESFHAAVHALLEWLADAEQALRFHGILPDDE--DSLRLLIEQHKEFMRRVEEKRSELNKGASMGEAILAICHPDSITTIKHWITIIRARFEEVLTWTKQHQQRLAVALDDLIAKKELLESLLAWLQWSEMTLNEKDKEDIPQDLDEVKALIEEHQIFMEEMTQKQPDVDKVTKTYKRKVESTTGQSQIPVLDKGRGGWKRSPTPSLYPSGTQTSLETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIEGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPITDADKIEDEVTRQVAKCKCAKRFQVEQIGENKYRVISLLFKFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGSKMLRSESNSSITTQPLI-AKGRTNVELREKFMLPEGASQSMTPFR------PKGRRSRPSSRGASPNRSN--SSPNIQASPSLAASSITPKTPLHLTRNYGKPWLANSKTSTPCKSPESPDYQLSSLETTPIQGSKLRLP 6085 HSP 2 Score: 124.02 bits (310), Expect = 9.703e-27 Identity = 66/136 (48.53%), Postives = 91/136 (66.91%), Query Frame = 3 Query: 705 WIIILF-FQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI 1109 +I LF FQ DI + +S+D+S K+ LL WS++ E Y I ENF+T W+DG+ F A+IHK RPDLIDL +++ S NLE AF A+K LGV ++++PEDV DEKS++TYVAS+++ PK D E I Sbjct: 137 YICFLFNFQISDIHVTGESEDMSAKEKLLLWSQQTSEGYGGIRCENFTTCWRDGRLFNAIIHKYRPDLIDLDTVAVQSNITNLENAFYVAEK-LGVTRLLDPEDVDVSSPDEKSVITYVASMYDAFPKTPDGGEGI 271 HSP 3 Score: 101.293 bits (251), Expect = 7.670e-20 Identity = 89/460 (19.35%), Postives = 208/460 (45.22%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDL---DGLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSN 3182 +WI+E + + +DL +G + ++ F E + S+ E KM E + ++ +S L++++++L + + F+ ++ + W+ KE++++ + W + + K++ +L+ EL+ +E I + + + NH A + I+ A ++++W WIL L HC++ H+ + Y ++F +A +A + L + + ++ L + E L +E + E + YK TV ++ ++++ L R + + ++AIC K+ + + E + L +NS W+V + P++CF + + +A +A ++ + + LW + + ++ V L++ ++ ++ L P Q+++ L + + D + + I ++I + +N C + EL S+ Q ++ N Sbjct: 620 SWIEEMQVQLDRAEWGSDLSSIEGHLENHKNFDRAVEEFESSLKEAKMS-EPQITGIFKANYDESLYKLESQYSKLLNSSRNRQKHLDTLHSFVSRATRELIWLNEKEEEEVAYDWSERNQ-NIPAKRDYHGDLMRELDHKEEIIKSVQDIAEQMLLQNHPARSTIEAYRAAMQTQWNWILQLCHCVEQHIRQNSAYFEYFNDAKDAAEYLKSLKDAILRKYSCDKSTSLHKLEDLLQESMEEKEQLLQYKSTVGSLVGKAKAIIQLKPRNPDNPLKASIPIRAICDYKQ---IEITIYKDDECI-LASNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDSANRIEQMYQSVLTLWHESHINMKSTVSWHYLMNEIEGIRASKVSTIKTLLPGEHQQVLSNLKSRFDEFLEDSQESKIFSMSDIAQLEREVNVCKLYYEELLKSAEREEQEESIYN 1073 HSP 4 Score: 90.8929 bits (224), Expect = 9.864e-17 Identity = 200/1025 (19.51%), Postives = 452/1025 (44.10%), Query Frame = 3 Query: 10767 VPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMS--PTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESEN----------LSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMI------GKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQI-----LQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDI----NNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKH-YPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPXXXXXXXXXXXXXXXXXXXXESXXXXXXXXXXXXXXXXXXXQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQ---------------PIDVS-KLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNA------TLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAE--QKIETAEKSMHKID---NLAAINEKIIESIDDRQNSLILQHKIVTEFE------SKKNDFIRKIDEANNDPELAKL----LNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESI 13646 P + K LD+++ + + A + + + + +F + ++ + KE M +VLGP+ + Q QQV L+ E + + ++ R+ GQ I+ P+S EV ++E L ++ K ++L L DR I + S ++ + +S++L+ + + TN++ S + + +L + K + K+ N L + L ++++ E+ ++ + + +++ K + V+ + ++ HH ED + W+Q K ++ N E I L NI + I +Q +K + S E + E + ++ K+ + +L++L + E I+ + NNL Q+A+ + N I+ WI+ +HK+++ V L +I+S + ++ K+++ + + L + ES L + + + E K + Q+ +N++ + L K T+ +E+ + + +KQ P S K + ++T Q + ++P ++ ++ S+AQ V+A T L + E + ++ ++ + +K +L +K + + ++ I ++ L +++D+ DL+ L+ Q D++ K LS+L + EN + +K+ E S I +L A+N++ + +D ++ I++ E + D ++ ++E + +N+ AF +++++PL+ +++E+ +G + + +E +++ V ++ L V+ + L+ +F +LE+L ++ + + +++ PS E+ K+QL +LL L R+ +++ + + G + + + K ++ +L L +++ LL AE +N + D + +++ F D EP WL + EK LA + T A ++ ++I + K L++D ++ ++S+ Sbjct: 3187 APESSKWKEMLDKIDSLWQDINKMAAERQQTLEESSNDLNQFQTAEAQLKQWLTEKELMASVLGPLSIDPNMLKTQKQQVQILLKEFDARKQQYEQFRSAGQRILNRPCELPSSGEV--VKEQLASVACKWESLTGQLNDRCDRIEQAIVKSTNYQNNLKGLSEKLSAMSNTL---STNMVVSSHPDAVNQKLQTAKQLQKDLSNEKKNIEDTKVLCQELSNLVAEDYLKAELNRQMDTVVKPFVDLEEKAGYHVEQLQMAFASSQKFHHLS------EDLKSWIQTKTKEQN----EAAPISANL--NILESLITEQAEVQNALKDQLSTYEKVTAEAENLLQKTKGDEKAN-LQSQLSMLKSNWEAINKQVLERQNNLLDCQQKATKHKEFVEN----IQPWIEECQHKLSEFTVSVDLSAIESSVGQVKVLQKNVDKQRGMMETLNS----------------------ATESLLNCCQTDKEAIREQNKNMNSQVDELIDNLHIKRDTLEKFGTRLKEFQESVKDTEKQLAVAQEHLDAHNSLGPQGCSNKHLTIMQTQQKVLQNLEPQID----IVRSLAQQLVVDAFDAEGVTELVLQAESLHQKHHIIHQEVEEKCSFLETKLQGIGHFQNSIREMFSQFTELDDELDSMTPVGRDLNILQCQKQDISKFL-------KKLSDLITTNENANKTCKKMLATESSPDLIGIKRDLEALNKQCNKLLDRAKSREEQTENIISRTEDFYCTLKQFFDLLKGVEEHEESQGAVGMETDVINHQLNIFMAFQKEEIEPLQARIQEVNQLGQGLVQSAAKNTSTESLEHDLEEVNVRWNTLNNKVAQRAAQLQEALLHSGRFQDALESLLSWLTDTEDLVASQKPPSAEFKVVKAQLQEQKLLQRLLSDRKPTVEAIKREGEKIASSADQTDKEKILKQLSTLERRWDELLKKAEIRNRQLDDILVVAEQFHDSLEPLSEWLTSTEKKLAISEPIGTQTA-KLLQQISQQKALEDDITAHNKSL 4155
BLAST of Dystonin vs. Ensembl Xenopus
Match: rab11fip2 (RAB11 family interacting protein 2 (class I) [Source:Xenbase;Acc:XB-GENE-5947669]) HSP 1 Score: 794.653 bits (2051), Expect = 0.000e+0 Identity = 525/1576 (33.31%), Postives = 867/1576 (55.01%), Query Frame = 3 Query: 14754 QLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDS-KKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPL-----IPIFDRS----KRMETNQGI-SKIQEPLFV-NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKY-------KFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGD--CECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVS------SPRIPQPVTSPRISQNIPSSRVSQSLASPRTP 19373 QL+ A+ L +F +Y L WL+ETE + Q + LD D L + +++I+ L + KP +D + K+G L + +G I A Y+ IKE +K RA L++ I + + ++K+D L+ I +R+ S EK+ E+L + +L+KLQ + L+ E +R DKD S ++ +KL ++ + +Q+ T E + +++++L LA +FW D + F + T I +L+ V+ ++++ E ++ EID + ++ + G +LI P++ P V + +EL ++ + + ++++ +D + ++ L +W ++ + P+ T+ V QI + K+ K D + ++E +N Q L K + N K V L+ + W L D + RQH+L+ LL+LG F A+DE W+ TE L K GD ++E+ LA+H +++ D+ +++V +++ ++I+ SS G EA+ RLE L + W+ + + + L+ AL +A F+ + +++ + + ++ +L K GGLP+TA+EQL +++ F ++ +++S ++ ++ + I+ D+ L +KW++V RK++LE+A+E FH + FINWLT E+ L P S I+ T+L Q++ H+ ++ SHR++++ LDK THLKY SQK D+V+I+NL+ S+ RWE VV RS ER R LD K +K+F + L++ + + L+ + I P KI+ Q+TKHKEF LG + YD+T R G L++KA + D +K+D+++ ++ KW ++C KSIER+ L +ALL+SG + DA+ L+ WL IEP+L++ + GD++ V L++ H + +K+L R I+ + A L+ S +DSS+++ Q+ EL + W V L+ K+ RLEEA +QA F ++L E+ + +E LR I P++E + + +I H F + + ++N G IL +P++ +IKH+I II++++ ++L+W++Q L LD L +K LL+ LL WL +E TL + ++ L E K EH+ F+ +MT KQ D D++ K+K IP+ D+ KR T S Q L NP++N L SKW+QVW + L RR++L D ++ L+E+ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFI+GI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C+ +++ Q G+ KY KFGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCRV H G + S+++ L+ AKGRTN ELREK P+G +M PF+ P + +++ SP S SSP I S +P+ P +T + +S+ S SP +P Sbjct: 4681 QLERAVSLVNQFWETYEELWPWLIETENAISQLPVPALDYDTLKQQQEDIRQLRELIAEHKPHIDKMNKTGPQLLDLSPE-EGFFIQEKYVSADTLYSEIKEVVKKRAIYLDEAISQSAQFHDKIDPTLENLQRIAERLRQPPSISAECEKIKEQLSENKNVSVELEKLQPVYETLKKRGEEMI-ARSEGADKDISAKVVQ-------------DKLDQMVFVWEDIQALTEEREAQLLDVLELAEKFWCDHYALIATFKD-----TQDLIRELDGPGVDPSVVKEQQETAEVIKEEIDGFQDELDAVISLGSELISACGEPDK-PVVNKNIDELTSAWDTLNKTWKERVEKLDEAMQAAVQYQDGLQALYDWVDIATLKVESMPPIGTDLVTVKQQIVELKQFKTDTYQQQIELERLNHQKELLLKKVTDENDKQAVEDPLSELKLLWNSLEDKIINRQHKLEGALLALGPFQHALDELTTWMTHTEGLLNEQKSVGGDPKAIEIELAKHHVLQNDVLAHKSTVETVKKAGNDLIE---SSAGEEASSLNSRLESLNQRWQIILDKTEKRMKLLDSALFQAQGFHSEIEDMHQWLTDIERQLLASKPVGGLPETAREQLSAHLELCSLFEVKEEIYKRLMQKSQQMMERCTDDPEANIDQDVINLKEKWESVDTKLSERKAKLEEALEVATGFHNSLQDFINWLTQAEQTLTIASPPSLILDTVLFQIDEHKVFVTEVNSHRDQIMELDKTGTHLKYFSQKQDVVIIKNLLISVQSRWENVVQRSLERGRMLDDARKRSKQFHEAFDKLMEWLEESERSLDSELEIANDPDKIKTQLTKHKEFQKTLGGKHTVYDTTTRSGRSLKEKATLTDDIQKLDDMLSEIRDKWDTVCGKSIERQNKLEEALLISGQFTDALQALIDWLYRIEPQLAED-QPVHGDIDIVMNLIDNHKVFQKELGKRSSSIQALKRSARELIEGSRDDSSWVKAQMQELGTRWETVCNLSVSKQTRLEEALHQAESFHAAVHALLEWLADAEQALRFHGILPDDE--DSLRLLIEQHKEFMRRVEEKRSELNKGASMGEAILAICHPDSITTIKHWITIIRARFEEVLTWTKQHQQRLAVALDDLIAKKELLESLLAWLQWSEMTLNEKDKEDIPQDLDEVKALIEEHQIFMEEMTQKQPDVDKVTKTYKRKVESTTGQSQIPVLDKGRGGWKRSPTPSLYPSGTQTSLETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIEGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPITDADKIEDEVTRQVAKCKCAKRFQVEQIGENKYRVISLLFKFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGSKMLRSESNSSITTQPLI-AKGRTNVELREKFMLPEGASQSMTPFR------PKGRRSRPSSRGASPNRSN--SSPNIQASPSLAASSITPKTPLHLTRNYGKPWLANSKTSTPCKSPESP 6218 HSP 2 Score: 258.455 bits (659), Expect = 2.651e-67 Identity = 130/247 (52.63%), Postives = 173/247 (70.04%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI 1109 LDP +R VLR+ADERD +QK+TF WIN HLMK+ K V D++ DLRDG L++LLEVLS L + RFH L+N+ LD+L+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +S+D+S K+ LL WS++ E Y I ENF+T W+DG+ F A+IHK RPDLIDL +++ S NLE AF A+K LGV ++++PEDV DEKS++TYVAS+++ PK D E I Sbjct: 194 LDPAERAVLRIADERDKVQKKTFTKWINQHLMKVRKHVSDLYEDLRDGHNLISLLEVLSGDTLPREKGRMRFHRLQNVQIALDYLKKRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKEKLLLWSQQTSEGYGGIRCENFTTCWRDGRLFNAIIHKYRPDLIDLDTVAVQSNITNLENAFYVAEK-LGVTRLLDPEDVDVSSPDEKSVITYVASMYDAFPKTPDGGEGI 439 HSP 3 Score: 98.2117 bits (243), Expect = 6.430e-19 Identity = 89/460 (19.35%), Postives = 208/460 (45.22%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDL---DGLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSN 3182 +WI+E + + +DL +G + ++ F E + S+ E KM E + ++ +S L++++++L + + F+ ++ + W+ KE++++ + W + + K++ +L+ EL+ +E I + + + NH A + I+ A ++++W WIL L HC++ H+ + Y ++F +A +A + L + + ++ L + E L +E + E + YK TV ++ ++++ L R + + ++AIC K+ + + E + L +NS W+V + P++CF + + +A +A ++ + + LW + + ++ V L++ ++ ++ L P Q+++ L + + D + + I ++I + +N C + EL S+ Q ++ N Sbjct: 788 SWIEEMQVQLDRAEWGSDLSSIEGHLENHKNFDRAVEEFESSLKEAKMS-EPQITGIFKANYDESLYKLESQYSKLLNSSRNRQKHLDTLHSFVSRATRELIWLNEKEEEEVAYDWSERNQ-NIPAKRDYHGDLMRELDHKEEIIKSVQDIAEQMLLQNHPARSTIEAYRAAMQTQWNWILQLCHCVEQHIRQNSAYFEYFNDAKDAAEYLKSLKDAILRKYSCDKSTSLHKLEDLLQESMEK-EQLLQYKSTVGSLVGKAKAIIQLKPRNPDNPLKASIPIRAICDYKQ---IEITIYKDDECI-LASNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDSANRIEQMYQSVLTLWHESHINMKSTVSWHYLMNEIEGIRASKVSTIKTLLPGEHQQVLSNLKSRFDEFLEDSQESKIFSMSDIAQLEREVNVCKLYYEELLKSAEREEQEESIYN 1240 HSP 4 Score: 89.3521 bits (220), Expect = 3.493e-16 Identity = 195/987 (19.76%), Postives = 438/987 (44.38%), Query Frame = 3 Query: 10881 MKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMS--PTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESEN----------LSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMI------GKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQI-----LQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDI----NNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKH-YPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPXXXXXXXXXXXXXXXXXXXXESXXXXXXXXXXXXXXXXXXXQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQ---------------PIDVS-KLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNA------TLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAE--QKIETAEKSMHKID---NLAAINEKIIESIDDRQNSLILQHKIVTEFE------SKKNDFIRKIDEANNDPELAKL----LNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESI 13646 + +F + ++ + KE M +VLGP+ + Q QQV L+ E + + ++ R+ GQ I+ P+S EV ++E L ++ K ++L L DR I + S ++ + +S++L+ + + TN++ S + + +L + K + K+ N L + L ++++ E+ ++ + + +++ K + V+ + ++ HH ED + W+Q K ++ N E I L NI + I +Q +K + S E + E + ++ K+ + +L++L + E I+ + NNL Q+A+ + N I+ WI+ +HK+++ V L +I+S + ++ K+++ + + L + ES L + + + E K + Q+ +N++ + L K T+ +E+ + + +KQ P S K + ++T Q + ++P ++ ++ S+AQ V+A T L + E + ++ ++ + +K +L +K + + ++ I ++ L +++D+ DL+ L+ Q D++ K LS+L + EN + +K+ E S I +L A+N++ + +D ++ I++ E + D ++ ++E + +N+ AF +++++PL+ +++E+ +G + + +E +++ V ++ L V+ + L+ +F +LE+L ++ + + +++ PS E+ K+QL +LL L R+ +++ + + G + + + K ++ +L L +++ LL AE +N + D + +++ F D EP WL + EK LA + T A ++ ++I + K L++D ++ ++S+ Sbjct: 3378 LNQFQTAEAQLKQWLTEKELMASVLGPLSIDPNMLKTQKQQVQILLKEFDARKQQYEQFRSAGQRILNRPCELPSSGEV--VKEQLASVACKWESLTGQLNDRCDRIEQAIVKSTNYQNNLKGLSEKLSAMSNTL---STNMVVSSHPDAVNQKLQTAKQLQKDLSNEKKNIEDTKVLCQELSNLVAEDYLKAELNRQMDTVVKPFVDLEEKAGYHVEQLQMAFASSQKFHHLS------EDLKSWIQTKTKEQN----EAAPISANL--NILESLITEQAEVQNALKDQLSTYEKVTAEAENLLQKTKGDEKAN-LQSQLSMLKSNWEAINKQVLERQNNLLDCQQKATKHKEFVEN----IQPWIEECQHKLSEFTVSVDLSAIESSVGQVKVLQKNVDKQRGMMETLNS----------------------ATESLLNCCQTDKEAIREQNKNMNSQVDELIDNLHIKRDTLEKFGTRLKEFQESVKDTEKQLAVAQEHLDAHNSLGPQGCSNKHLTIMQTQQKVLQNLEPQID----IVRSLAQQLVVDAFDAEGVTELVLQAESLHQKHHIIHQEVEEKCSFLETKLQGIGHFQNSIREMFSQFTELDDELDSMTPVGRDLNILQCQKQDISKFL-------KKLSDLITTNENANKTCKKMLATESSPDLIGIKRDLEALNKQCNKLLDRAKSREEQTENIISRTEDFYCTLKQFFDLLKGVEEHEESQGAVGMETDVINHQLNIFMAFQKEEIEPLQARIQEVNQLGQGLVQSAAKNTSTESLEHDLEEVNVRWNTLNNKVAQRAAQLQEALLHSGRFQDALESLLSWLTDTEDLVASQKPPSAEFKVVKAQLQEQKLLQRLLSDRKPTVEAIKREGEKIASSADQTDKEKILKQLSTLERRWDELLKKAEIRNRQLDDILVVAEQFHDSLEPLSEWLTSTEKKLAISEPIGTQTA-KLLQQISQQKALEDDITAHNKSL 4308
BLAST of Dystonin vs. Ensembl Mouse
Match: Dst (dystonin [Source:MGI Symbol;Acc:MGI:104627]) HSP 1 Score: 850.507 bits (2196), Expect = 0.000e+0 Identity = 690/2474 (27.89%), Postives = 1250/2474 (50.53%), Query Frame = 3 Query: 12426 EMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKS------EVENLAEQKIETAEKSMHKID---NLAAINE---KIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIG-------AFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSID-TKNKINKLFDRFSEYQ-KSHYXXXXXXXXXXXXXXXXXDQVNLFE--DTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETL----KNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLAN----NKLDLVLPSLTALVRENDSLTG----QVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAF------ENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKL-QIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWND-LKLIEDKFHEMTIHLTNSTIEDL-----NTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSK-KIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKT--PPL----IPIFDRSKRMETNQGISKIQEPLFV-----------NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGD--CECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF--KFKPATLPIPTKKPTTAKIPSPRVSQ--------PLSSPRIHQPVS----SPRIP-QPVTSPRISQNIPSSRVSQSLASP------RTPKVVASPGLQ--------------------RKSRIPTRQTSQQGSQASTRHQSR 19472 + E + + LS + +K +L +K ++ Q +RE F + +LD + D LR++ ++ L L++ + + T E S I +L A+++ K+++ R+ + + + EF K +F + +A E + ++ I F +++++PL+ + +++ +G + + + +E ++DSV + L + V+ + + L+ +F +LE+L ++ + + ++ PS E+ K+Q+ +LL L+ R+S+++ + + G + + + + +L +L L++++E LL+ AE +N + + +++ F + EP WL EK LAN + T A ++E++I ++K L++D ++ + + + + I + V S D ++K++ L + E Q KSH L N D+V L + ++G K KL++ D + +W + E+++ +E + +++DQ G +L + ++ ++ I K+ + + +I+ + E+++ +A + + N LD V L L E L G QV ER E L+NE S + LV D L V + + E +E E+ +R++ V + +T+K +I + +++ E+ D + ++ ++K+ + D + + ++L+ K ++L K+ I+ + K++ + + +S+K +D+V K+ ++ + + QL+ A L +F +Y L WL ET+ + Q L+ + L + ++E + L + KP +D + K+G L ++ + +G I A Y+ IKE +K RA L++ I +T+ ++K+DQ LE I +R+ S EK+ E++G + D++KLQ + L Q G E + R +KD ++ R ++ L+++ I S + + E + K+++++ LA +FW D + L+ +TI T I DL + V +++ E +R EID ++++ + G +LI P++ P V+++ +EL ++++ + + ++ ++ + ++ + +W N+L + P+ T+ V QI++ K+ K++ + ++E +N Q L K + K+ V L + W L + + RQH+L+ LL+LG+F A+DE + W+ T+ L+ K GD ++E+ LA+H +++ D+ Q++V + + ++I+ SS G EA+ +L L + W+++ E + +L+ AL++A F+G+ +++ + + + L K GGLP+TAKEQL M++ F + + ++ + +S I+ D+ L +KW++VK+ +K++LE+A+ FH + FINWLT E+ LN S I+ TIL Q++ H+ ++ SHRE+++ LDK THLKY SQK D+VLI+NL+ S+ RWEKVV R ER R+LD K AK+F + L++ + + + L+ + I P KI+ Q+ +HKEF +LG + YD+T R G L++K + D K+D ++ L+ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + A L+ S +DSS++ Q+ EL + W V L+ K+ RLE A QA EF + ++L E+ +++E LR P++E + + +I H F K L +++ G +L +P++ +IKH+I II++++ ++L+W++Q L L L ++ LL+ LL WL AE TL + + + E K EH+ F+ +MT KQ D D++ K++ PP IP+ D+ + G + F NP++N L SKW+QVW + L RR++L D ++ L+E+ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C+ +++ Q GD KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCRV H G + S+++ + AKGRTN ELREK G MA F + + + P + S Q S+P+I P++ P + +++P + P VS + +P R P ++ G + P+R S+ GS+A +R SR Sbjct: 5253 QAETLAEEHSELSQQVDEKCSFLETK----------LQGLGHFQNTIREMFSQFTECDDELDGMAPVGRDAETLRKQKACMQTFLKKLEALMASNDSANRTCKMMLATEETSPDLIGVKRDLEALSKQCNKLLDRAKTREEQVDGATEKLEEFHRKLEEFSTLLQKAEEHEESQGPVGTETETINQQLDVFKVFQKEEIEPLQVKQQDVNWLGQGLIQSAAANTCTQGLEHDLDSVNSRWKTLNKKVAQRTSQLQEALLHCGRFQDALESLLSWMADTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLEDRKSTVEVIKREGEKIAASAEPADRVKLTRQLSLLDSRWEALLSRAEARNRQLEGISVVAQEFHETLEPLNEWLTAVEKKLANSEPIGT-QAPKLEEQISQHKVLEDDITNHSKQLHQ-AVSIGQSLKVLSSREDKDLVQSKLDSLQVWYFEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHG-----KLSKLSVQD-HSPEALWRQR----AELRALQEDILLRKQSVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSADVAKTLEHALQLAGQLQSMHKELCNWLDKVEVEL--LSYETQGLKGEAASQVQERQKE-LKNEVRSNKALV-------DSLNEVSSALLELVPWRAREGLEKTIAEDNERYRLVSDTITQKVEEIDAAILRSQQFEQAADAELSWITETQKKLMSLGDIRLEQDQTSAQLQVQKAFTMDIL----RHKDIIDELVTSGHKIMTTSSEEEKQSMKKKLDKVLKKYDAVCQINSERHLQLERAQSLVSQFWETYEELWPWLTETQRIISQLPAPALEYETLRRQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSPK-EGIYIQEKYVAADTLYSQIKEDVKKRAVVLDEAISQSTQFHDKIDQILESLERIAERLRQPPSISAEVEKIKEQIGENKSVSVDMEKLQPLYETLRQRGEEMIA--RSEGTEKD----------VSARAVQDKLDQMVFIWGS---IHTLVEEREAKLLDVMELAEKFWCDHMSLV------VTIKDTQDFIRDLEDPGIDPSVVKQQQEAAEAIREEIDGLQEELDMVITLGSELIAACGEPDK-PIVKKSIDELNSAWDSLNKAWKDRVDRLEEAMQAAVQYQDGLQGIFDWVDIAGNKLATMSPIGTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEEADKHTVQDPLMELKLIWDSLDERIVSRQHKLEGALLALGQFQHALDELLAWLTHTKGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIE---SSEGEEASNLQYKLRILNQRWQDILEKTDQRKQQLDSALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNAHMEVCTAFAIKEETYKSLMLRGQQMLARCPRSAETNIDQDITNLKEKWESVKSKLNEKKTKLEEALHLAMNFHNSLQDFINWLTQAEQTLNVASRPSLILDTILFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDEARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKAQLVQHKEFQKSLGGKHSVYDTTNRTGRSLKEKTSLADDNLKLDNMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAED-QPVHGDIDLVMNLIDNHKVFQKELGKRTSSVQALKRSARELIEGSRDDSSWVRVQMQELSTRWETVCALSISKQTRLESALQQAEEFHSVVHTLLEWLAEAEQTLRFHGALPDDE--DALRTLIEQHKEFMKRLEEKRAELSKATGMGDALLAVCHPDSITTIKHWITIIQARFEEVLAWAKQHQQRLAGALAGLIAKQELLETLLAWLQWAETTLTEKDKEVIPQEIEEVKTLIAEHQTFMEEMTRKQPDVDKVTKTYKRRATDPPSLQSHIPVLDKGR-----AGRKRFPASGFYPSGSQTQIETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPITDADKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGSKMLRSESNSSITATQPTLAKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSASSHACQAASPPVPAAASTPKILHPLTRNYGKPWLANSKMSTPCKAAECPDFPVSSAEGTPIQGSKLRLPGYLSGKGFHSGEDSALITTAAARVRTQFAESRKTPSRPGSRAGSKAGSRASSR 7654 HSP 2 Score: 255.758 bits (652), Expect = 1.444e-66 Identity = 127/247 (51.42%), Postives = 174/247 (70.45%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI 1109 LDP +R VLR+ADERD +QK+TF WIN HLMK+ K V D++ DLRDG L++LLEVLS L + RFH L+N+ LD+L+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +S+D+S K+ LL W+++A E Y + ENF+T W+DGK F A+IHK RPDLID+ +++ S NLE AF A+K +GV ++++PEDV DEKS++TYV+SL++ PK + E I Sbjct: 197 LDPAERAVLRIADERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKERLLLWTQQATEGYAGVRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPKVPEGGEGI 442 HSP 3 Score: 98.9821 bits (245), Expect = 3.415e-19 Identity = 91/467 (19.49%), Postives = 205/467 (43.90%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSN 3182 NW+DE + + +DL + ++ E+F ++ E K + E +M + + + + L++++ +L + + F+ ++ + W+ KE+ ++ + W + S ++ K+ L+ ELE +E SI + L + NH A I+ A ++++W WIL L C++ H++ + Y +FF +A EA + + L + + ++ + + E L +E + E ++ Y+ V ++ +++V L R + + +KAIC ++ + + E + L NNS W+V + P++CF + + +A A ++ + + LW + + ++ V L++ +D ++ + P Q+++ L + D + + I ++I++ ++ C + EL S+ Q +V N Sbjct: 791 NWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAK--ISEIQMT------APLKLSYTDKLHRLESQYAKLLNTSRNQERHLDTLHNFVTRATNELIWLNEKEESEVAYDWSERNS-SVARKKSYHAELMRELEQKEESIKAVQEIAEQLLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIQENSAYFEFFNDAKEATDYLRNLKDAIQRKYSCDRSSSIHKLEDLVQESMEKEELLQ-YRSVVAGLMGRAKTVVQLKPRNPDNPLKTSIPIKAICDYRQ---IEITIYKDDECV-LANNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDFANRIEQQYQSVLTLWHESHINMKSVVSWHYLVNEIDRIRASNVASIKTMLPGEHQQVLSNLQSRLEDFLEDSQESQIFSGSDISQLEKEVSVCRKYYQELLKSAEREEQEESVYN 1243
BLAST of Dystonin vs. Ensembl Mouse
Match: Dst (dystonin [Source:MGI Symbol;Acc:MGI:104627]) HSP 1 Score: 842.803 bits (2176), Expect = 0.000e+0 Identity = 686/2470 (27.77%), Postives = 1239/2470 (50.16%), Query Frame = 3 Query: 12426 EMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKS------EVENLAEQKIETAEKSMHKID---NLAAINE---KIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIG-------AFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSID-TKNKINKLFDRFSEYQ-KSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETL----KNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLAN----NKLDLVLPSLTALVRENDSLTG----QVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAF------ENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKL-QIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWND-LKLIEDKFHEMTIHLTNSTIEDL-----NTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSK-KIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKT--PPL----IPIFDRSKRMETNQGISKIQEPLFV-----------NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF--KFKPATLPIPTKKPTTAKIPSPRVSQ--------PLSSPRIHQPVS----SPRIP-QPVTSPRISQNIPSSRVSQSLASP------RTPKVVASPGLQ--------------------RKSRIPTRQTSQQGSQASTRHQSR 19472 + E + + LS + +K +L +K + + Q +RE F + +LD + D LR++ ++ L L++ + + T E S I +L A+++ K+++ R+ + + + EF K +F + +A E + ++ I F +++++PL+ + +++ +G + + + +E ++DSV + L + V+ + + L+ +F +LE+L ++ + + ++ PS E+ K+Q+ +LL L+ R+S+++ + + G + + + + +L +L L++++E LL+ AE +N + + +++ F + EP WL EK LAN + T A ++E++I ++K L++D ++ + + + + I + V S D ++K++ L + E Q KSH L N D+V L + E K KL++ D + +W + E+++ +E + +++DQ G +L + ++ ++ I K+ + + +I+ + E+++ +A + + N LD V L L E L G QV ER E L+NE S + LV D L V + + E +E E+ +R++ V + +T+K +I + +++ E+ D + ++ ++K+ + D + + ++L+ K ++L K+ I+ + K++ + + +S+K +D+V K+ ++ + + QL+ A L +F +Y L WL ET+ + Q L+ + L + ++E + L + KP +D + K+G L ++ + +G I A Y+ IKE +K RA L++ I +T+ ++K+DQ LE I +R+ S EK+ E++G + D++KLQ + L Q G E + R +KD ++ R ++ L+++ I S + + E + K+++++ LA +FW D + L+ +TI T I DL + V +++ E +R EID ++++ + G +LI P++ P V+++ +EL ++++ + + ++ ++ + ++ + +W N+L + P+ T+ V QI++ K+ K++ + ++E +N Q L K + K+ V L + W L + + RQH+L+ LL+LG+F A+DE + W+ T+ L+ K GD ++E+ LA+H +++ D+ Q++V + + ++I+ SS G EA+ +L L + W+++ E + +L+ AL++A F+G+ +++ + + + L K GGLP+TAKEQL M++ F + + ++ + +S I+ D+ L +KW++VK+ +K++LE+A+ FH + FINWLT E+ LN S I+ TIL Q++ H+ ++ SHRE+++ LDK THLKY SQK D+VLI+NL+ S+ RWEKVV R ER R+LD K AK+F + L++ + + + L+ + I P KI+ Q+ +HKEF +LG + YD+T R G L++K + D K+D ++ L+ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + A L+ S +DSS++ Q+ EL + W V L+ K+ RLE A QA EF + ++L E+ +++E LR P++E + + +I H F K L +++ G +L +P++ +IKH+I II++++ ++L+W++Q L L L ++ LL+ LL WL AE TL + + + E K EH+ F+ +MT KQ D D++ K++ PP IP+ D+ + G + F NP++N L SKW+QVW + L RR++L D ++ L+E+ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C+ +++ Q GD KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR AKGRTN ELREK G MA F + + + P + S Q S+P+I P++ P + +++P + P VS + +P R P ++ G + P+R S+ GS+A +R SR Sbjct: 2735 QAETLAEEHSELSQQVDEKCSFLETKLQGLGHF----------QNTIREMFSQFTECDDELDGMAPVGRDAETLRKQKACMQTFLKKLEALMASNDSANRTCKMMLATEETSPDLIGVKRDLEALSKQCNKLLDRAKTREEQVDGATEKLEEFHRKLEEFSTLLQKAEEHEESQGPVGTETETINQQLDVFKVFQKEEIEPLQVKQQDVNWLGQGLIQSAAANTCTQGLEHDLDSVNSRWKTLNKKVAQRTSQLQEALLHCGRFQDALESLLSWMADTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLEDRKSTVEVIKREGEKIAASAEPADRVKLTRQLSLLDSRWEALLSRAEARNRQLEGISVVAQEFHETLEPLNEWLTAVEKKLANSEPIGT-QAPKLEEQISQHKVLEDDITNHSKQLHQ-AVSIGQSLKVLSSREDKDLVQSKLDSLQVWYFEIQEKSHSRSELLQQALCNAKIFGEDEVELMN---WLNEVHGKLSKLSVQD-HSPEALWRQR----AELRALQEDILLRKQSVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSADVAKTLEHALQLAGQLQSMHKELCNWLDKVEVEL--LSYETQGLKGEAASQVQERQKE-LKNEVRSNKALV-------DSLNEVSSALLELVPWRAREGLEKTIAEDNERYRLVSDTITQKVEEIDAAILRSQQFEQAADAELSWITETQKKLMSLGDIRLEQDQTSAQLQVQKAFTMDIL----RHKDIIDELVTSGHKIMTTSSEEEKQSMKKKLDKVLKKYDAVCQINSERHLQLERAQSLVSQFWETYEELWPWLTETQRIISQLPAPALEYETLRRQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSPK-EGIYIQEKYVAADTLYSQIKEDVKKRAVVLDEAISQSTQFHDKIDQILESLERIAERLRQPPSISAEVEKIKEQIGENKSVSVDMEKLQPLYETLRQRGEEMIA--RSEGTEKD----------VSARAVQDKLDQMVFIWGS---IHTLVEEREAKLLDVMELAEKFWCDHMSLV------VTIKDTQDFIRDLEDPGIDPSVVKQQQEAAEAIREEIDGLQEELDMVITLGSELIAACGEPDK-PIVKKSIDELNSAWDSLNKAWKDRVDRLEEAMQAAVQYQDGLQGIFDWVDIAGNKLATMSPIGTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEEADKHTVQDPLMELKLIWDSLDERIVSRQHKLEGALLALGQFQHALDELLAWLTHTKGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIE---SSEGEEASNLQYKLRILNQRWQDILEKTDQRKQQLDSALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNAHMEVCTAFAIKEETYKSLMLRGQQMLARCPRSAETNIDQDITNLKEKWESVKSKLNEKKTKLEEALHLAMNFHNSLQDFINWLTQAEQTLNVASRPSLILDTILFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDEARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKAQLVQHKEFQKSLGGKHSVYDTTNRTGRSLKEKTSLADDNLKLDNMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAED-QPVHGDIDLVMNLIDNHKVFQKELGKRTSSVQALKRSARELIEGSRDDSSWVRVQMQELSTRWETVCALSISKQTRLESALQQAEEFHSVVHTLLEWLAEAEQTLRFHGALPDDE--DALRTLIEQHKEFMKRLEEKRAELSKATGMGDALLAVCHPDSITTIKHWITIIQARFEEVLAWAKQHQQRLAGALAGLIAKQELLETLLAWLQWAETTLTEKDKEVIPQEIEEVKTLIAEHQTFMEEMTRKQPDVDKVTKTYKRRATDPPSLQSHIPVLDKGR-----AGRKRFPASGFYPSGSQTQIETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPITDADKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------AKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSASSHACQAASPPVPAAASTPKILHPLTRNYGKPWLANSKMSTPCKAAECPDFPVSSAEGTPIQGSKLRLPGYLSGKGFHSGEDSALITTAAARVRTQFAESRKTPSRPGSRAGSKAGSRASSR 5112 HSP 2 Score: 97.8265 bits (242), Expect = 6.053e-19 Identity = 93/476 (19.54%), Postives = 209/476 (43.91%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAV 3209 NW+DE + + +DL + ++ E+F ++ E K + E +M + + + + L++++ +L + + F+ ++ + W+ KE+ ++ + W + S ++ K+ L+ ELE +E SI + L + NH A I+ A ++++W WIL L C++ H++ + Y +FF +A EA + + L + + ++ + + E L +E + E ++ Y+ V ++ +++V L R + + +KAIC ++ + + E + L NNS W+V + P++CF + + +A A ++ + + LW + + ++ V L++ +D ++ + P Q+++ L + D + + I ++I++ ++ C + EL S+ Q +V N S V+ + Sbjct: 287 NWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAK--ISEIQMT------APLKLSYTDKLHRLESQYAKLLNTSRNQERHLDTLHNFVTRATNELIWLNEKEESEVAYDWSERNS-SVARKKSYHAELMRELEQKEESIKAVQEIAEQLLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIQENSAYFEFFNDAKEATDYLRNLKDAIQRKYSCDRSSSIHKLEDLVQESMEKEELLQ-YRSVVAGLMGRAKTVVQLKPRNPDNPLKTSIPIKAICDYRQ---IEITIYKDDECV-LANNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDFANRIEQQYQSVLTLWHESHINMKSVVSWHYLVNEIDRIRASNVASIKTMLPGEHQQVLSNLQSRLEDFLEDSQESQIFSGSDISQLEKEVSVCRKYYQELLKSAEREEQEESVYNLYISEVRNI 748
BLAST of Dystonin vs. Ensembl Mouse
Match: Macf1 (microtubule-actin crosslinking factor 1 [Source:MGI Symbol;Acc:MGI:108559]) HSP 1 Score: 830.861 bits (2145), Expect = 0.000e+0 Identity = 765/3008 (25.43%), Postives = 1431/3008 (47.57%), Query Frame = 3 Query: 10827 LKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRS---MSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDW--------EEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQ-------WLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQI-----LQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPXXXXXXXXXXXXXXXXXXXXESXXXXXXXXXXXXXXXXXXXQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISP--VNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINE---KIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAK--------------LLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQ----NDDSSIDESIKKLK----IIINKVDGVFSENVSIDTKNKINKLFDRFSEYQ-KSHYXXXXXXXXXXXXXXXXXDQVNLF------EDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVREND----SLTGQ--VGERNMEILENETNSVEKLVCQARNDLDKLKSVD------AFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMS------DQINNDYSELEECKIDFTNLLSAWNE---QKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSP------SRKNANDKDDSV-EISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLG-YQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTF-PKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQ-DSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKT--PPLIPIFDRSK---RMETNQGISKIQEPLFV-------NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF-----KFKPAT---------LPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPV-TSPRIS-----QNIPSSRVSQSLASPRTPKVVAS-PGLQRKSRIPTRQTSQQGSQAS 19454 L++SA HL + +SQ++ + ++ KE M+ VLGP+ + NAQ QQV ++ E E ++L Q I+ MSP++S+V + L +S+K L L R I + S + L+ D+S+++ + +++ + + T + EI+++L + + +KE++ L + L I ++ E+K ++ ++ + ++ D+ R + L + +Q WL KQ Q + P + Q Q+ Q ++ E I E + P + K + ++L L + E++ N + K + WID K KM++ V L+ + E LL K++ N+ ++ L +++ + + + + +++ +E L+E E K+ K+E A+ L+ ++ Q LE ++K Q + ++P ++ + + + +P +A+ L + E + + ++ + + +K + + + R+ ++ +L +++D D DSL+ QI D+ + + + + ++E + E++ + + L A+N+ K+ E RQ L L V DF RK+ N+ A+ ++N + F + +VDPL+ +L+++ +G + + +E +MD + ++ L + V+ + L+ KF +LE L ++ + + ++ PS EY K+Q+ +LL L R++++D L G + + + + ++ +L+ L ++ +LL+ A + + + + L+K F + EP +L EK LAN + T A ++ ++I +K L+ N + + +++K + + G+ SE K++ L R+SE Q + + L N D+V + ED L +KD + +++ + L L +E+ + + KN+DQ G+ L + ++ + I K++ + + +I++++ K L E + +A +F LT +RE + + GQ GE+ + + ++K V + R LD + V + E ++ + + +++K + + V ++ +I + +++ E+ D + ++ ++K+ + DQ + ID + +E + I ST + +K + L+ + + +Q E+ + + +L+ A L +F +Y L W ET + Q +D +QL + ++E++ L S + KP +D I+K G L ++ N +GK + + A+ Y IK+ ++ RA L++ + + + ++K++ LEN+ R+ P + P ++D+ E + D + ++KLQ E R DKD + EI D + + E+ +++++ E + K +++L LA +FW D+ + TI T + DL + ++ + + E ++ E D +++ I G LI E P+V+++ +E+ +E + + ++++ ++ + ++ + +W +L + P+ T+ V Q+ + KE K ++ + ++E +N G L K + ++ + L + W L + + RQH+L+ LL+LG+F A++E + W+ TE L + GD +E+ LA+H +++ D+ QA+V+ + + +E+++ SS G +A+ RLE + + WE + + + +L+ L++A F+ + ++ ++ + ++L K +GGLP+TA+EQL M+++ K I + + + + G E + +L +KW V + E RKS+LE+A+ F + +FINWLTL E++LN P S I++T+L Q+E H+ ++ HR++++ LD+ LK++SQK D+VLI+NL+ S+ RWEKVV RS ER R+LD K AK+F + + L+D + L+ + I P KI+ Q++KHKEF LG YD+T R G L++K + D++K+D ++ ++ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + L+ S +D+++++ QL EL + W+ V KL+ K+ RLE+A QA EF + L E+ S++E LR P++ E + ++I H F K + + +N G IL +P+ +IKH+I II++++ ++L+W++Q L+ L L LL++LL W+ AE TL+ + + + K EH+ F+ +MT KQ D D + K+K+ P P ++S+ R NQ P+ + NP+INQL ++W+QVW + L R+++L D ++ L+E++ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF TT++EM VADIFD++ G+IDY +F+AAL P+++ Y +P + + I DEV +Q+++C C+ +++ Q G+ KY+FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR A+GRTN ELREK P+G M PF + KP++ + +PS + + I S + P P S R S N S + + A+ PK AS PG + SR +R +S++GS AS Sbjct: 2411 LEESAS-HLACFQAAESQLRPW----------LMEKELMMGVLGPLSIDPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGILTGPGDMSPSASQV---HKDLQSISQKWVELTDKLNSRSSQIDQAIVKSTQYQDLLQDLSEKVKAIGQRLS-GQSAISTQPEAVKQQLEETSEIRSDLGQLDNEIKEAQTLCQELSLLIGEQYLKDELKKRLETVALPLQGLE-------DLAADRMNRLQAALASTQQFQQMFDELRTWLDEKQSQ------QAKNCPISAKLERLQCQLQENEEFQKNLNQHSGSYEVIVAEGEALLLSVPPGEEKKTLQNQLVELRSHWEDLSKKTANRQSRLKDCMQKAQKYQGHVEDLVPWIDECKSKMSE-LQVTLDPVQLESSLLR--SKAMLNEAEKRRSLLEILNSAADILINSSEIDEDEIRDEKAGLNQNMDAITEELQAKTSSLEEMTQRLKEFQESFKNIEKKVEG-AKHQLEIFDALGSQACSNKNLE-KLKAQQEVLQALEPQVDYLRNFTQGLVEDAPDGSDASPLVHQAEVAQQEFLEVKQRVSSSCLTMENKLEGIGQFHCRVREMFSQLADLDDELDGMGAIGRDTDSLQSQIEDVRLFLNKIQALRFDIEDSEAECRKMLEEEGTLDLLGLKR--ELEALNKQCGKLTERGKVRQEQLELTLGRV-------EDFYRKLKALNDAATAAEEGEALQWIVGTEVDVINQQLADFKLFQKDQVDPLQVKLQQVNGLGQGLIQSAGKNCDVQGLEHDMDEINTRWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLTDTEELIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQLESLERRWTDLLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA-KIHQQIIRHKALEEEIENHATDVHQAVKIGQSLSSLTCPAEQGIMSE--------KLDSLQARYSEIQDRCCRKASLLEQALFNARLFGEDEVEVLNWLAEVEDKLSTV--FVKDYRQDVLQKQHA-----DHLALNEEIINRK---KNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITLTSSKALRTLEQARQLATKF-------HSTYEELTGWLREAEEELAASGGQSPTGEQ-IPQFQQRQKELKKEVMEHRLVLDTVNEVSHALLELVPWRAREGLDKLVSDANEQYKLISDTVGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRGEIFSTCGEEQKAV----------LQEKTECLIQQYEAVSLLNSERYARLERAQVLVNQFWETYEELSPWAEETLALIAQLPPPAVDHEQLRQQQEEMRQLRESIAEHKPHIDKILKIGPQLKEL-NPEEGKMVEEKYQKAENMYAQIKDEVRQRALALDEAVSQSAQFHDKIEPMLETLENLSSRL---RMPPLIPAEVDK----IRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWED--------------IKARSEEREIKFLDVLELAEKFWYDMAALL-----TTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGE-TEKPEVKKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVATVNKAGSELLE---SSAGDDASSLRSRLETMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELNRMENQLSASKPTGGLPETAREQLDTHMELHSQLRAKEEIYNQLLDKGRLMLLSRGDSGSGSKTEQSVALLEQKWHAVSSKVEERKSKLEEALSLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNDHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLAGDTQKLDNLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAED-QPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIEGSRDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEEFRDTVHMLLEWLSEAEQTLRFRGALPDDT--EALQSLIDTHKEFMKKVEEKRVDVNTAVAMGEAILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALITEHQSFMEEMTRKQPDVDRVTKTYKRKSVEPTHAPFMEKSRSGSRKSLNQPTPP---PMPILSQSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAY--RPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------ARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVISSSGSKLKRPTPAFHSSRTSLAGDTSNSSSPASTGAKANRADPKKSASRPGSRAGSRAGSRASSRRGSDAS 5278 HSP 2 Score: 198.364 bits (503), Expect = 2.942e-49 Identity = 99/206 (48.06%), Postives = 140/206 (67.96%), Query Frame = 3 Query: 468 INKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPK 1085 + K + D++ DLRDG L++LLEVLS KL + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI S +S D+S K+ LL W++K Y + NFS+ W DGK F ALIH+ RPDL+D++ + S ++NLE AF A++ LGV ++++ EDV DEKS++TYV+S+++ PK Sbjct: 1 VRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGVKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQVQSNRENLEQAFEVAER-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPK 205 HSP 3 Score: 111.309 bits (277), Expect = 5.352e-23 Identity = 161/837 (19.24%), Postives = 367/837 (43.85%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGLN---KIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSK----NDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLS------TMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLK-CANIDENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDL-QLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQ-----VCKHKEFETNLKNYEPQVNDLIL----FVK---NGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKD---VPTNLDQLISAVTTSRQNQKDVSYE---DIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFESKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYEDIFKNYQNEIQNQIGGSNQDYFGYTKRSRIQNAHDWVSCE 4238 +W++E + + NDL + + + T+ E+ SV E ++ + +M +FH S L+T++ +L S +S +F+ ++ + W+ KE++++ W D+ + +S K+ F L ELE ++ L++ NH A ++ A ++S+ QW+ L C++ H++ A Y QFF +A + ++ + L + + ++ L E L ++ D E + K +V ++ S+++ L R + + ++VKAIC ++ + + L +NS W+V + P++CFLI + +A + A ++ + + LW +L + + L+S +D V+ W+ E +L P ++++ L + D A + + + C A F L M+++ N+ E+ V + +L ++ + + Q L ++ SP D Q + + + + +L++ ++ + + F++ +G S T L+ +L M++ + ++ + +++ KLK+ +V + + + ++ E+ L +Q E+ PA ++ LE+ + T+ + ++KD V + LD+ I+ + + + E D+++ +++ ++ R+ + Q++ R S V + + WI +TT + ++ P +S+ + + + EI + + ++D+ K + + +++ YE Y+ +++Q Q G KR R+ ++ D ++ E Sbjct: 500 SWVEEMQMKLERAEWGNDLPSVELQLETQQHIHTSVEELGSSVKEARLY-----EGKMSQNFHTSYVETLGKLETQYCKLKETSSFRMRHLQSLHKFVSRATAELIWLNGKEEEELACDWSDS-NPNISAKKTYFSELTMELEGKQDVFRSLQDTAEVLSLENHPAKQTVEAYSAAVQSQLQWMKQLCLCVEQHVKENAAYFQFFSDARDLESFLRNLQDSIKRKYTCDRSTSLSRLEDLLQDSMDEKEQLIQSKSSVASLVGRSKTIVQLKPRNPDHVLKSTLSVKAICDYRQ----IEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNKEAIEMASRVEQSYQKVMALW--HQLHINTKSLISWNYLRKDLDTVQTWSLEKLRSLAPGECHQVMKNLQAHYEDFLQDSHDSALFSVADRLRIEEEVEACKAHFQHL---------MKSLENED-------KEETLAKVYISELKNIRLLLEECEQRLLKQIQSPASSKTDRDARQDITLRIAEQEHTQEDLQHLRSDLDAISMKCNVFLQQSPSGSSATT-LRSELNLMVEKMDHVYGLSTVYLNKLKTIDVIVRSMQDAELLVKGYEIKL-SQEEAVPAD-------LSALESHRTTLQHWLSDVKDKNSVFSVLDEEITKAKKVAEQLRHPASEPNLDLERYQEKGSQLQERWHRVIAQLETRQSEVESIQEVLRDYRACHGTLIKWIE--ETTAQQEMMKPGQAEDSRVLSEQLSQQTELFAEIERNQTKLDQCQKFSQQYSTIVKDYELQLMTYKAFVESQ-----QKSPG--KRRRMISSSDAITQE 1290 HSP 4 Score: 55.0694 bits (131), Expect = 4.705e-6 Identity = 116/614 (18.89%), Postives = 264/614 (43.00%), Query Frame = 3 Query: 16068 INDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSL--TNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRL-EQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDE---LGSKLEMFKFSGGLPDTAKEQ----LKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKY-ISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMN---RTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKI--DEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQ---TLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQF 17852 +N + +L + L +RQ LQ + + E + ++W+ + E L + + +++ +K A++ + + K++ A ++K +S E +++ E L WE+ E A+ +LE++ F + ++ + E + L + + K+Q LK F + +LN + + ++S +SQ + D++ + +KW + + +R S++++AI + + + + L+ Q +S + +Q+E ++ D+ E+ + L I +++ ++ + ++ + + +++R L ++F+ M RT LD+ S ++ I +++ Q+ +++EF NL H+ +Y+ G L P + KK +++V L+ W+ L K+ R+ L D + + Y+ + +L+ W+ + K+S+ ++ VQ +LL ++L + R ++E +N+ A L+ SE D I D+ A L + + + K LEE + EF+ + ++++ ++H+L F Sbjct: 2281 VNSKYEKLWEVLRERQESLQTVFSRMEEVQKEASSVLQWLESKEEVLKAMDATLSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLKTYPNSQEAENWKKMQEDLNSRWEKATEVTVARQKQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLSIDPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGILTGPGDMSPSASQ-----VHKDLQSISQKWVELTDKLNSRSSQIDQAIVKSTQYQDLLQDLSEKVKAIGQRLSGQSAISTQPEAVKQQLEETSEIRSDLGQLDNEIKEAQTLCQELSLLIGEQYLKDELKKRLETVALPLQGLEDLAADRMNRLQAALASTQQFQQMFDELRTWLDEKQSQQA---KNCPISAKLERLQCQLQENEEFQKNLNQHSGSYEVIVAEGEALLLSVPPGEEKKTLQNQLV-ELRSHWEDLSKKTANRQSRLKDCMQKAQKYQGHVEDLVPWIDECKSKMSE----LQVTLDPVQLESSLLRSKAML-NEAEKRRSLLEILNSAADILINSSEIDEDEIRDEKAGLNQNMDAITEELQAKTSSLEEMTQRLKEFQESFKNIEKKVEGAKHQLEIF 2880
BLAST of Dystonin vs. Ensembl Mouse
Match: Dst (dystonin [Source:MGI Symbol;Acc:MGI:104627]) HSP 1 Score: 803.127 bits (2073), Expect = 0.000e+0 Identity = 565/1820 (31.04%), Postives = 972/1820 (53.41%), Query Frame = 3 Query: 14193 LVRENDSLTG----QVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAF------ENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKL-QIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWND-LKLIEDKFHEMTIHLTNSTIEDL-----NTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSK-KIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKT--PPL----IPIFDRSKRMETNQGISKIQEPLFV-----------NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGD--CECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF-----KFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSP------RIPQPVTSPRISQNIPSSRVSQSLASPRTP-----KVVASPGLQRKSRIPTRQTSQQGSQAS 19454 L E L G QV ER E L+NE S + LV D L V + + E +E E+ +R++ V + +T+K +I + +++ E+ D + ++ ++K+ + D + + ++L+ K ++L K+ I+ + K++ + + +S+K +D+V K+ ++ + + QL+ A L +F +Y L WL ET+ + Q L+ + L + ++E + L + KP +D + K+G L ++ + +G I A Y+ IKE +K RA L++ I +T+ ++K+DQ LE I +R+ S EK+ E++G + D++KLQ + L Q G E + R +KD ++ R ++ L+++ I S + + E + K+++++ LA +FW D + L+ +TI T I DL + V +++ E +R EID ++++ + G +LI P++ P V+++ +EL ++++ + + ++ ++ + ++ + +W N+L + P+ T+ V QI++ K+ K++ + ++E +N Q L K + K+ V L + W L + + RQH+L+ LL+LG+F A+DE + W+ T+ L+ K GD ++E+ LA+H +++ D+ Q++V + + ++I+ SS G EA+ +L L + W+++ E + +L+ AL++A F+G+ +++ + + + L K GGLP+TAKEQL M++ F + + ++ + +S I+ D+ L +KW++VK+ +K++LE+A+ FH + FINWLT E+ LN S I+ TIL Q++ H+ ++ SHRE+++ LDK THLKY SQK D+VLI+NL+ S+ RWEKVV R ER R+LD K AK+F + L++ + + + L+ + I P KI+ Q+ +HKEF +LG + YD+T R G L++K + D K+D ++ L+ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + A L+ S +DSS++ Q+ EL + W V L+ K+ RLE A QA EF + ++L E+ +++E LR P++E + + +I H F K L +++ G +L +P++ +IKH+I II++++ ++L+W++Q L L L ++ LL+ LL WL AE TL + + + E K EH+ F+ +MT KQ D D++ K++ PP IP+ D+ + G + F NP++N L SKW+QVW + L RR++L D ++ L+E+ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C+ +++ Q GD KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCRV H G + S+++ + AKGRTN ELREK G MA F + +P++ + T+A + + + P P +P R+P ++ S+ ++ + A RT K + PG + S+ +R +S++GS AS Sbjct: 3551 LSYETQGLKGEAASQVQERQKE-LKNEVRSNKALV-------DSLNEVSSALLELVPWRAREGLEKTIAEDNERYRLVSDTITQKVEEIDAAILRSQQFEQAADAELSWITETQKKLMSLGDIRLEQDQTSAQLQVQKAFTMDIL----RHKDIIDELVTSGHKIMTTSSEEEKQSMKKKLDKVLKKYDAVCQINSERHLQLERAQSLVSQFWETYEELWPWLTETQRIISQLPAPALEYETLRRQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSPK-EGIYIQEKYVAADTLYSQIKEDVKKRAVVLDEAISQSTQFHDKIDQILESLERIAERLRQPPSISAEVEKIKEQIGENKSVSVDMEKLQPLYETLRQRGEEMIA--RSEGTEKD----------VSARAVQDKLDQMVFIWGS---IHTLVEEREAKLLDVMELAEKFWCDHMSLV------VTIKDTQDFIRDLEDPGIDPSVVKQQQEAAEAIREEIDGLQEELDMVITLGSELIAACGEPDK-PIVKKSIDELNSAWDSLNKAWKDRVDRLEEAMQAAVQYQDGLQGIFDWVDIAGNKLATMSPIGTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEEADKHTVQDPLMELKLIWDSLDERIVSRQHKLEGALLALGQFQHALDELLAWLTHTKGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIE---SSEGEEASNLQYKLRILNQRWQDILEKTDQRKQQLDSALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNAHMEVCTAFAIKEETYKSLMLRGQQMLARCPRSAETNIDQDITNLKEKWESVKSKLNEKKTKLEEALHLAMNFHNSLQDFINWLTQAEQTLNVASRPSLILDTILFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDEARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKAQLVQHKEFQKSLGGKHSVYDTTNRTGRSLKEKTSLADDNLKLDNMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAED-QPVHGDIDLVMNLIDNHKVFQKELGKRTSSVQALKRSARELIEGSRDDSSWVRVQMQELSTRWETVCALSISKQTRLESALQQAEEFHSVVHTLLEWLAEAEQTLRFHGALPDDE--DALRTLIEQHKEFMKRLEEKRAELSKATGMGDALLAVCHPDSITTIKHWITIIQARFEEVLAWAKQHQQRLAGALAGLIAKQELLETLLAWLQWAETTLTEKDKEVIPQEIEEVKTLIAEHQTFMEEMTRKQPDVDKVTKTYKRRATDPPSLQSHIPVLDKGR-----AGRKRFPASGFYPSGSQTQIETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPITDADKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGSKMLRSESNSSITATQPTLAKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSASSHACQAASPPVPAAASTPKGTPIQGSKLRLPGYLSGKGFHSGEDSALITTAAARVRTQFAESRKTPSRPGSRAGSKAGSRASSRRGSDAS 5322 HSP 2 Score: 239.58 bits (610), Expect = 1.154e-61 Identity = 119/239 (49.79%), Postives = 166/239 (69.46%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPK 1085 L + ++ R DERD +QK+TF WIN HLMK+ K V D++ DLRDG L++LLEVLS L + RFH L+N+ LD+L+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +S+D+S K+ LL W+++A E Y + ENF+T W+DGK F A+IHK RPDLID+ +++ S NLE AF A+K +GV ++++PEDV DEKS++TYV+SL++ PK Sbjct: 19 LQAYEDVLERYKDERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKERLLLWTQQATEGYAGVRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 256 HSP 3 Score: 98.5969 bits (244), Expect = 3.497e-19 Identity = 93/476 (19.54%), Postives = 209/476 (43.91%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAV 3209 NW+DE + + +DL + ++ E+F ++ E K + E +M + + + + L++++ +L + + F+ ++ + W+ KE+ ++ + W + S ++ K+ L+ ELE +E SI + L + NH A I+ A ++++W WIL L C++ H++ + Y +FF +A EA + + L + + ++ + + E L +E + E ++ Y+ V ++ +++V L R + + +KAIC ++ + + E + L NNS W+V + P++CF + + +A A ++ + + LW + + ++ V L++ +D ++ + P Q+++ L + D + + I ++I++ ++ C + EL S+ Q +V N S V+ + Sbjct: 613 NWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAK--ISEIQMTAP------LKLSYTDKLHRLESQYAKLLNTSRNQERHLDTLHNFVTRATNELIWLNEKEESEVAYDWSERNS-SVARKKSYHAELMRELEQKEESIKAVQEIAEQLLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIQENSAYFEFFNDAKEATDYLRNLKDAIQRKYSCDRSSSIHKLEDLVQESMEKEELLQ-YRSVVAGLMGRAKTVVQLKPRNPDNPLKTSIPIKAICDYRQ---IEITIYKDDECV-LANNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDFANRIEQQYQSVLTLWHESHINMKSVVSWHYLVNEIDRIRASNVASIKTMLPGEHQQVLSNLQSRLEDFLEDSQESQIFSGSDISQLEKEVSVCRKYYQELLKSAEREEQEESVYNLYISEVRNI 1074 HSP 4 Score: 78.5666 bits (192), Expect = 4.254e-13 Identity = 87/430 (20.23%), Postives = 197/430 (45.81%), Query Frame = 3 Query: 12426 EMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKS------EVENLAEQKIETAEKSMHKID---NLAAINE---KIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIG-------AFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND----DSSIDESI 13646 + E + + LS + +K +L +K + + Q +RE F + +LD + D LR++ ++ L L++ + + T E S I +L A+++ K+++ R+ + + + EF K +F + +A E + ++ I F +++++PL+ + +++ +G + + + +E ++DSV + L + V+ + + L+ +F +LE+L ++ + + ++ PS E+ K+Q+ +LL L+ R+S+++ + + G + + + + +L +L L++++E LL+ AE +N + + +++ F + EP WL EK LAN + T A ++E++I ++K LQ D S+D+++ Sbjct: 3061 QAETLAEEHSELSQQVDEKCSFLETKLQGLGHF----------QNTIREMFSQFTECDDELDGMAPVGRDAETLRKQKACMQTFLKKLEALMASNDSANRTCKMMLATEETSPDLIGVKRDLEALSKQCNKLLDRAKTREEQVDGATEKLEEFHRKLEEFSTLLQKAEEHEESQGPVGTETETINQQLDVFKVFQKEEIEPLQVKQQDVNWLGQGLIQSAAANTCTQGLEHDLDSVNSRWKTLNKKVAQRTSQLQEALLHCGRFQDALESLLSWMADTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLEDRKSTVEVIKREGEKIAASAEPADRVKLTRQLSLLDSRWEALLSRAEARNRQLEGISVVAQEFHETLEPLNEWLTAVEKKLANSEPIGT-QAPKLEEQISQHKALQEDILLRKQSVDQAL 3479 HSP 5 Score: 61.6178 bits (148), Expect = 6.285e-8 Identity = 54/233 (23.18%), Postives = 110/233 (47.21%), Query Frame = 3 Query: 15894 PLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKF-SGGLPDTAKEQLK 16589 P E + V QIQ+ K L+ +E + +E+I + G ++ + P + ++ L+ ++ W LL R QL+ I + EFH ++ EW+ A E L N + LE ++QHK ++ D+ + + SV + E++K+ +LE ++ ++++ + + LE AL+ A +E+ +D++ ++E+ + + GL A Q++ Sbjct: 3337 PPSAEFKVVKAQIQEQKLLQRLLEDRKSTVEVIKREGEKIAASAEPADRVKLTRQLSLLDSRWEALLSRAEARNRQLEGISVVAQEFHETLEPLNEWLTAVEKKLANSEPIGTQAPKLEEQISQHKALQEDILLRKQSVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSADVAKTLEHALQLAGQLQSMHKELCNWLDKV--EVELLSYETQGLKGEAASQVQ 3567
BLAST of Dystonin vs. Ensembl Mouse
Match: Dst (dystonin [Source:MGI Symbol;Acc:MGI:104627]) HSP 1 Score: 800.431 bits (2066), Expect = 0.000e+0 Identity = 566/1820 (31.10%), Postives = 972/1820 (53.41%), Query Frame = 3 Query: 14193 LVRENDSLTG----QVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSL------EKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKL-QIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWND-LKLIEDKFHEMTIHLTNSTIEDL-----NTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSK-KIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKT--PPL----IPIFDRSKRMETNQGISKIQEPLFV-----------NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGD--CECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF-----KFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSP------RIPQPVTSPRISQNIPSSRVSQSLASPRTP-----KVVASPGLQRKSRIPTRQTSQQGSQAS 19454 L E L G QV ER E L+NE S + LV D L V + L E +E E+ +R++ V + +T+K +I + +++ E+ D + ++ ++K+ + D + + ++L+ K ++L K+ I+ + K++ + + +S+K +D+V K+ ++ + + QL+ A L +F +Y L WL ET+ + Q L+ + L + ++E + L + KP +D + K+G L ++ + +G I A Y+ IKE +K RA L++ I +T+ ++K+DQ LE I +R+ S EK+ E++G + D++KLQ + L Q G E + R +KD ++ R ++ L+++ I S + + E + K+++++ LA +FW D + L+ +TI T I DL + V +++ E +R EID ++++ + G +LI P++ P V+++ +EL ++++ + + ++ ++ + ++ + +W N+L + P+ T+ V QI++ K+ K++ + ++E +N Q L K + K+ V L + W L + + RQH+L+ LL+LG+F A+DE + W+ T+ L+ K GD ++E+ LA+H +++ D+ Q++V + + ++I+ SS G EA+ +L L + W+++ E + +L+ AL++A F+G+ +++ + + + L K GGLP+TAKEQL M++ F + + ++ + +S I+ D+ L +KW++VK+ +K++LE+A+ FH + FINWLT E+ LN S I+ TIL Q++ H+ ++ SHRE+++ LDK THLKY SQK D+VLI+NL+ S+ RWEKVV R ER R+LD K AK+F + L++ + + + L+ + I P KI+ Q+ +HKEF +LG + YD+T R G L++K + D K+D ++ L+ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + A L+ S +DSS++ Q+ EL + W V L+ K+ RLE A QA EF + ++L E+ +++E LR P++E + + +I H F K L +++ G +L +P++ +IKH+I II++++ ++L+W++Q L L L ++ LL+ LL WL AE TL + + + E K EH+ F+ +MT KQ D D++ K++ PP IP+ D+ + G + F NP++N L SKW+QVW + L RR++L D ++ L+E+ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C+ +++ Q GD KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCRV H G + S+++ + AKGRTN ELREK G MA F + +P++ + T+A + + + P P +P R+P ++ S+ ++ + A RT K + PG + S+ +R +S++GS AS Sbjct: 5565 LSYETQGLKGEAASQVQERQKE-LKNEVRSNKALV-------DSLNEVSSALLELVPWRAREGLEKTIAEDNERYRLVSDTITQKVEEIDAAILRSQQFEQAADAELSWITETQKKLMSLGDIRLEQDQTSAQLQVQKAFTMDIL----RHKDIIDELVTSGHKIMTTSSEEEKQSMKKKLDKVLKKYDAVCQINSERHLQLERAQSLVSQFWETYEELWPWLTETQRIISQLPAPALEYETLRRQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSPK-EGIYIQEKYVAADTLYSQIKEDVKKRAVVLDEAISQSTQFHDKIDQILESLERIAERLRQPPSISAEVEKIKEQIGENKSVSVDMEKLQPLYETLRQRGEEMIA--RSEGTEKD----------VSARAVQDKLDQMVFIWGS---IHTLVEEREAKLLDVMELAEKFWCDHMSLV------VTIKDTQDFIRDLEDPGIDPSVVKQQQEAAEAIREEIDGLQEELDMVITLGSELIAACGEPDK-PIVKKSIDELNSAWDSLNKAWKDRVDRLEEAMQAAVQYQDGLQGIFDWVDIAGNKLATMSPIGTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEEADKHTVQDPLMELKLIWDSLDERIVSRQHKLEGALLALGQFQHALDELLAWLTHTKGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIE---SSEGEEASNLQYKLRILNQRWQDILEKTDQRKQQLDSALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNAHMEVCTAFAIKEETYKSLMLRGQQMLARCPRSAETNIDQDITNLKEKWESVKSKLNEKKTKLEEALHLAMNFHNSLQDFINWLTQAEQTLNVASRPSLILDTILFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDEARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKAQLVQHKEFQKSLGGKHSVYDTTNRTGRSLKEKTSLADDNLKLDNMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAED-QPVHGDIDLVMNLIDNHKVFQKELGKRTSSVQALKRSARELIEGSRDDSSWVRVQMQELSTRWETVCALSISKQTRLESALQQAEEFHSVVHTLLEWLAEAEQTLRFHGALPDDE--DALRTLIEQHKEFMKRLEEKRAELSKATGMGDALLAVCHPDSITTIKHWITIIQARFEEVLAWAKQHQQRLAGALAGLIAKQELLETLLAWLQWAETTLTEKDKEVIPQEIEEVKTLIAEHQTFMEEMTRKQPDVDKVTKTYKRRATDPPSLQSHIPVLDKGR-----AGRKRFPASGFYPSGSQTQIETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPITDADKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGSKMLRSESNSSITATQPTLAKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSASSHACQAASPPVPAAASTPKGTPIQGSKLRLPGYLSGKGFHSGEDSALITTAAARVRTQFAESRKTPSRPGSRAGSKAGSRASSRRGSDAS 7336 HSP 2 Score: 239.58 bits (610), Expect = 1.158e-61 Identity = 121/247 (48.99%), Postives = 169/247 (68.42%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI 1109 L + ++ R DERD +QK+TF WIN HLMK+ K V D++ DLRDG L++LLEVLS L + RFH L+N+ LD+L+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +S+D+S K+ LL W+++A E Y + ENF+T W+DGK F A+IHK RPDLID+ +++ S NLE AF A+K +GV ++++PEDV DEKS++TYV+SL++ PK + E I Sbjct: 19 LQAYEDVLERYKDERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKERLLLWTQQATEGYAGVRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPKVPEGGEGI 264 HSP 3 Score: 98.9821 bits (245), Expect = 2.717e-19 Identity = 91/467 (19.49%), Postives = 205/467 (43.90%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSN 3182 NW+DE + + +DL + ++ E+F ++ E K + E +M + + + + L++++ +L + + F+ ++ + W+ KE+ ++ + W + S ++ K+ L+ ELE +E SI + L + NH A I+ A ++++W WIL L C++ H++ + Y +FF +A EA + + L + + ++ + + E L +E + E ++ Y+ V ++ +++V L R + + +KAIC ++ + + E + L NNS W+V + P++CF + + +A A ++ + + LW + + ++ V L++ +D ++ + P Q+++ L + D + + I ++I++ ++ C + EL S+ Q +V N Sbjct: 613 NWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAK--ISEIQMT------APLKLSYTDKLHRLESQYAKLLNTSRNQERHLDTLHNFVTRATNELIWLNEKEESEVAYDWSERNS-SVARKKSYHAELMRELEQKEESIKAVQEIAEQLLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIQENSAYFEFFNDAKEATDYLRNLKDAIQRKYSCDRSSSIHKLEDLVQESMEKEELLQ-YRSVVAGLMGRAKTVVQLKPRNPDNPLKTSIPIKAICDYRQ---IEITIYKDDECV-LANNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDFANRIEQQYQSVLTLWHESHINMKSVVSWHYLVNEIDRIRASNVASIKTMLPGEHQQVLSNLQSRLEDFLEDSQESQIFSGSDISQLEKEVSVCRKYYQELLKSAEREEQEESVYN 1065 HSP 4 Score: 79.337 bits (194), Expect = 2.495e-13 Identity = 87/430 (20.23%), Postives = 197/430 (45.81%), Query Frame = 3 Query: 12426 EMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKS------EVENLAEQKIETAEKSMHKID---NLAAINE---KIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIG-------AFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND----DSSIDESI 13646 + E + + LS + +K +L +K ++ Q +RE F + +LD + D LR++ ++ L L++ + + T E S I +L A+++ K+++ R+ + + + EF K +F + +A E + ++ I F +++++PL+ + +++ +G + + + +E ++DSV + L + V+ + + L+ +F +LE+L ++ + + ++ PS E+ K+Q+ +LL L+ R+S+++ + + G + + + + +L +L L++++E LL+ AE +N + + +++ F + EP WL EK LAN + T A ++E++I ++K LQ D S+D+++ Sbjct: 5075 QAETLAEEHSELSQQVDEKCSFLETK----------LQGLGHFQNTIREMFSQFTECDDELDGMAPVGRDAETLRKQKACMQTFLKKLEALMASNDSANRTCKMMLATEETSPDLIGVKRDLEALSKQCNKLLDRAKTREEQVDGATEKLEEFHRKLEEFSTLLQKAEEHEESQGPVGTETETINQQLDVFKVFQKEEIEPLQVKQQDVNWLGQGLIQSAAANTCTQGLEHDLDSVNSRWKTLNKKVAQRTSQLQEALLHCGRFQDALESLLSWMADTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLEDRKSTVEVIKREGEKIAASAEPADRVKLTRQLSLLDSRWEALLSRAEARNRQLEGISVVAQEFHETLEPLNEWLTAVEKKLANSEPIGT-QAPKLEEQISQHKALQEDILLRKQSVDQAL 5493 HSP 5 Score: 61.2326 bits (147), Expect = 8.254e-8 Identity = 55/246 (22.36%), Postives = 113/246 (45.93%), Query Frame = 3 Query: 15855 WFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKF-SGGLPDTAKEQLK 16589 W + + P E + V QIQ+ K L+ +E + +E+I + G ++ + P + ++ L+ ++ W LL R QL+ I + EFH ++ EW+ A E L N + LE ++QHK ++ D+ + + SV + E++K+ +LE ++ ++++ + + LE AL+ A +E+ +D++ ++E+ + + GL A Q++ Sbjct: 5338 WMADTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLEDRKSTVEVIKREGEKIAASAEPADRVKLTRQLSLLDSRWEALLSRAEARNRQLEGISVVAQEFHETLEPLNEWLTAVEKKLANSEPIGTQAPKLEEQISQHKALQEDILLRKQSVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSADVAKTLEHALQLAGQLQSMHKELCNWLDKV--EVELLSYETQGLKGEAASQVQ 5581
BLAST of Dystonin vs. UniProt/SwissProt
Match: sp|Q03001|DYST_HUMAN (Dystonin OS=Homo sapiens OX=9606 GN=DST PE=1 SV=4) HSP 1 Score: 869.766 bits (2246), Expect = 0.000e+0 Identity = 687/2450 (28.04%), Postives = 1243/2450 (50.73%), Query Frame = 3 Query: 12426 EMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVEN------LAEQKIETAEKSMHKID---NLAAINE---KIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIG-------AFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND----------DSSIDESIKKLK------IIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETL----KNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNS-----VEKLVCQARNDLDKLKSVDAFENSL---------EKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKL-QIGIENCSPSRKNANDKDDSVE-ISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWND-LKLIEDKFHEMTIHLTNSTIEDL-----NTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSK-KIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTP------PLIPIFDRSKRMETNQGISKI-----QEPLFV-NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGD--CECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF--KFKPATLPIPTKKPTTAKIPSPRVSQPLSS--PRIHQPVSSP------RIPQPVTSPRISQNIPSSRVSQSLASPRT-----PKVVASPGLQRKSRIPTRQTSQQGSQAS 19454 ++E I + LS + +K +L +K ++ Q +RE F + +LDS+ D L+++ I+ L L++ + + + + T E S + +L A+++ K+++ R+ + K + EF SK +F + +A E + ++ I F +++++PL+ + +++ +G + + +E ++D V + L + V+ + L+ +F +LE+L ++ + + ++ PS E+ K+Q+ +LL L R+S+++ + + G + + K ++ +L L++++E LLN AE +N + + +++ F + EP WL T EK L N + T A ++E++I ++K L++D SI +S+K L ++ +K+D FS+ I+ + +KSH L N D+V L + E K KL++ D Y T +W++ E++ +E + +N+DQ G +L + ++ ++ I K+ + + +I+ + E ++ +A R + +L L D + ++ ++L+ E S ++L +A+N+ L S++ ++L E +E + E+ +R++ V + +T+K +I + +++ ++ D + ++ E+K+ + D + + ++L+ K +L K+ I+ + K++ + +S+K +D+V K ++ + + QL+ A L +F +Y L WL ET+ + Q L+ + L + ++E + L + KP +D + K+G L ++ + +G +I A Y+ IKE +K RA L++ I +T+ ++K+DQ LE I +R+ S EK+ E++ + D++KLQ + L Q G E + R DKD S + + D + + + EN + + E + K+++++ LA +FW D + LI +TI T I DL + V +++ E +R EID ++++ + G +LI P++ P V+++ +EL ++++ + + +I ++ + ++ + +W +L + P+ T+ V QI++ K+ K++ + ++E +N Q L K + + K+ V L + W L + + RQH+L+ LL+LG+F A+DE + W+ TE L+ K GD ++E+ LA+H +++ D+ Q++V + + ++I+ SS G EA+ +LE L + W+ + E + +L+ AL++A F+G+ +++ + + + L K GGLP+TAKEQL M++ F + +++ ++ + +S I+ D+ L +KW++V+ RK++LE+A+ FH + FINWLT E+ LN S I+ T+L Q++ H+ ++ SHRE+++ LDK THLKY SQK D+VLI+NL+ S+ RWEKVV R ER R+LD K AK+F + L++ + + + L+ + I P KI+ Q+ +HKEF +LG + YD+T R G L++K + D K+D+++ L+ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H +K+L R ++ + A L+ S +DSS+++ Q+ EL + W V L+ K+ RLE A QA EF + ++L E+ +++E LR + P++E + + +I H F K L ++N G +L +P++ +IKH+I II++++ ++L+W++Q L L L ++ LL+ LL WL AE TL + + + E K EH+ F+ +MT KQ D D++ K++ IP+ D+ + S + Q + NP++N L SKW+QVW + L RR++L D ++ L+E+ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C+ +++ Q GD KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCRV H G + S+++ + AKGRTN ELREK G MA F + + + P + S + +Q S P P +P R+P ++ S ++ + A RT K + PG + S+ +R +S++GS AS Sbjct: 5144 QVETIAQEHSTLSQQVDEKCSFLETK----------LQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKETIKAFLKKLEALMASNDNANKTCKMMLATEETSPDLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEESQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLEHDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGT-QASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKLD--FSQVWYIEIQ-------------EKSHSRSELLQQALCNAKIFGEDEVELMN---WLNEVHDKLSKLSVQD-YSTEGLWKQQ----SELRVLQEDILLRKQNVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTWL----------DKVEVELLSYETQVLKGEEASQAQMRPKELKKEAKNNKALLDSLNEVSSALLELVPWRAREGLEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDIRLEQDQTSAQLQVQKTFTMEIL----RHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLEL-SPGEGFSIQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIA--RSGGTDKDISAKAVQDKLDQMVFIWEN--------------IHTLVEEREAKLLDVMELAEKFWCDHMSLI------VTIKDTQDFIRDLEDPGIDPSVVKQQQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDK-PIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIE---SSAGEEASNLQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAED-QPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGSRDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDE--DALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKHWITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEVIPQEIEEVKALIAEHQTFMEEMTRKQPDVDKVTKTYKRRAADPSSLQSHIPVLDKGRAGRKRFPASSLYPSGSQTQIETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPITDADKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGSKMLRSESNSSITTTQPTIAKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSVSSQAAQAASPQVPATTTPKGTPIQGSKLRLPGYLSGKGFHSGEDSGLITTAAARVRTQFADSKKTPSRPGSRAGSKAGSRASSRRGSDAS 7513 HSP 2 Score: 239.58 bits (610), Expect = 7.054e-61 Identity = 120/239 (50.21%), Postives = 166/239 (69.46%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPK 1085 L + ++ R DERD +QK+TF WIN HLMK+ K V D++ DLRDG L++LLEVLS L + RFH L+N+ LD+L+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +S+D+S K+ LL W+++A E Y I ENF+T W+DGK F A+IHK RPDLID+ +++ S NLE AF A+K +GV ++++PEDV DEKS++TYV+SL++ PK Sbjct: 19 LQAYEDVLERYKDERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 256 HSP 3 Score: 104.375 bits (259), Expect = 5.357e-20 Identity = 102/525 (19.43%), Postives = 227/525 (43.24%), Query Frame = 3 Query: 1725 PTLSSGVISNRQYTPIHSMELGDNVLYSSL---------------NKWKNWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAV 3209 P SSGV N T + M++ +L SSL NW+DE + + +DL + ++ E+F ++ E K + E +M + + + + + L++++ +L + + F+ ++ + W+ KE++++ + W + + ++ K++ L+ EL+ +E +I + L + NH A I+ A ++++W WIL L C++ H++ Y +FF +A EA + + L + + ++ + + E L +E + E + YK T+ ++ ++++ L R + + + +KAIC ++ + + E + L NNS W+V + P++CF + + +A A ++ + + LW + + ++ V L++ +D ++ + P Q+++ L + D + + + ++I + +N C + EL S+ Q +V N S V+ + Sbjct: 565 PNFSSGVEPNSLQT-LKLMQIRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAK--ISEIQMT------APLKLTYAEKLHRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSE-RNTNIARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEATDYLRNLKDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQYKSTIANLMGKAKTIIQLKPRNSDCPLKTSIPIKAICDYRQ---IEITIYKDDECV-LANNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDLANRIEQQYQNVLTLWHESHINMKSVVSWHYLINEIDRIRASNVASIKTMLPGEHQQVLSNLQSRFEDFLEDSQESQVFSGSDITQLEKEVNVCKQYYQELLKSAEREEQEESVYNLYISEVRNI 1075
BLAST of Dystonin vs. UniProt/SwissProt
Match: sp|D3ZHV2|MACF1_RAT (Microtubule-actin cross-linking factor 1 OS=Rattus norvegicus OX=10116 GN=Macf1 PE=1 SV=1) HSP 1 Score: 815.068 bits (2104), Expect = 0.000e+0 Identity = 663/2413 (27.48%), Postives = 1191/2413 (49.36%), Query Frame = 3 Query: 12522 CKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINE---KIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPEL-------AKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQ----NDDSSIDESIKKLK----IIINKVDGVFSENVSIDTKNKINKLFDRFSEYQ-KSHYXXXXXXXXXXXXXXXXXDQVNLF------EDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRE-NDSLTGQVGE----RNMEILENETNSVEKLVCQARNDLDKLKSVD------AFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMS------DQINNDYSELEECKIDFTNLLSAWNE---QKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINT---ELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSP------SRKNANDKDDSV-EISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLG-YQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTF-PKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQD-SKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKT--PPLIPIFDRSK---RMETNQGISKIQEPLFV-------NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF-----KFKPAT---------LPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPV-----TSPRISQNIPSSRVSQSLASPRT-PKVVAS-PGLQRKSRIPTRQTSQQGSQAS 19454 C+ R E+F ++ +L +++D D DSL+ QI D+ + + + + ++E + E++ + + L A+N+ K+ E RQ L L V +F SK A L ++N + F +++VDPL+ +L+++ +G + + +E +M+ V ++ L + V+ + L+ KF +LE L ++ + + ++ PS EY K+Q+ +LL L R++++D L G + + + ++ +L+ L ++ LL+ A + + + + L+K F + EP +L EK LAN + T A ++ ++I +K L+ N + + +++K + +I G+ SE K++ L R+SE Q + + L N D+V + ED L +KD + +++ + L L +E+ + + KN+DQ G+ L + ++ + I K++ + + +I+V++ K L E + +A +F LT +RE + L G+ + + ++K V + R LD + V + E ++ + + +++K V + V ++ +I + +++ E+ D + ++ ++K+ + DQ + ID + +E + I ST + +K + L+ + + +Q E+ + + +L+ A L +F +Y L W ET + Q +D +QL + ++E++ L S + KP +D I+K G L ++ N +GK + + A+ Y IK+ ++ RA L++ + + E ++K++ LEN+ R+ P + P ++D+ E + D + ++KLQ E R DKD + EI D + + E+ +++++ E + K +++L LA +FW D+ + TI T + DL + ++ + + E ++ E D +++ I G LI E P+V+++ +E+ +E + + ++++ ++ + ++ + +W RL + P+ T+ V Q+ + KE K ++ + ++E +N G L K + ++ + L + W L + + RQH+L+ LL+LG+F A++E + W+ TE L + GD +E+ LA+H +++ D+ QA+V + + E+++ SS G +A+ RLE + + WE + + + +L+ L++A F+ + +E ++ + S+L K +GGLP+TA+EQL M+++ K I + + + + G E + +L +KW V + E RKS+LE+A+ F + +FINWLTL E++LN P S I++T+L Q+E H+ ++ +HR++++ LD+ LK++SQK D+VLI+NL+ S+ RWEKVV RS ER R+LD K AK+F + + L+D + L+ + I P KI+ Q++KHKEF LG YD+T R G L++K + D ++K+D ++ ++ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + L+ S +D+++++ QL EL + W+ V KL+ K+ RLE+A QA EF + L E+ S++E LR P++ E + ++I H F K + + +N G IL +P+ +IKH+I II++++ ++L+W++Q L+ L L LL++LL W+ AE TL+ + + + K EH+ F+ +MT KQ D D + K+K P P ++S+ R NQ P+ + NP+INQL ++W+QVW + L R+++L D ++ L+E++ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF TT++EM VADIFD++ G+IDY +F+AAL P+++ Y +P + + I DEV +Q+++C C+ +++ Q G+ KY+FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR A+GRTN ELREK P+G M PF + KP++ + +PS + + I S + P P TS + SS S + R PK AS PG + SR +R +S++GS AS Sbjct: 3064 CRVR-EMF-SQLADLDDELDGMGAIGRDTDSLQSQIEDIRLFLNKIQALRLDIEDSEAECRKMLEEEGTLDLLGLKR--ELEALNKQCGKLTERGKARQEQLELTLGRVEDFYSKLKALNDAATAAEEGEALQWIVGTEVDVINQQLADFKMFQKEQVDPLQVKLQQVNGLGQGLIQSAGKTCDVQGLEHDMEEVNTRWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLTDTEELIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQAAELADREKITGQLESLECRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTA-KIHQQIIRHKALEEEIENHAADVQQAVKIGQSLSSLICPAEQGIMSE--------KLDSLQARYSEIQDRCCRKASLLEQALFNARLFGEDEVEVLNWLAEVEDKLSAV--FVKDYRQDVLQKQHA-----DHLALNEEIINRK---KNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKF-------HSTYEELTGWLREVEEELAASGGQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSHALLELVPWRAREGLDKLVSDANEQYKLVSDTVGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRGEIFSTCGEEQKAV----------LQEKTECLIQQYEAVSLLNSERYARLERAQVLVNQFWETYEELSPWAEETLALIAQLPPPAVDHEQLRQQQEEMRQLRESIAEHKPHIDKILKIGPQLKEL-NPEEGKMVEEKYQKAENMYAQIKDEVRQRALALDEAVSQSAQIAEFHDKIEPMLETLENLSSRL---RMPPLIPAEVDK----IRECISDNKSATMELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWED--------------IKARSEEREIKFLDVLELAEKFWYDMAALL-----TTIKDTQEIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGE-TEKPEVKKSIDEMNNAWENLNRTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIRLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMGWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLE---SSAGDDASSLRSRLETMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEEFLLELNRMESQLSASKPTGGLPETAREQLDAHMELHSQLRAKEEIYNQLLDKGRLMLLSRGDSGSGSKTEQSVALLEQKWHVVSSKVEERKSKLEEALSLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLADDAQKLDNLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAED-QPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIESSRDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEEFRDTVHMLLEWLSEAEQTLRFRGALPDDT--EALQSLIDTHKEFMKKVEEKRVDVNAAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALITEHQSFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKSRSGSRKSLNQPTPP---PMPILSQSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAY--RPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------ARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVISSTGSKLKRPTPTFHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDAS 5375 HSP 2 Score: 248.825 bits (634), Expect = 1.053e-63 Identity = 122/239 (51.05%), Postives = 167/239 (69.87%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPK 1085 LDP +R V+RVADERD +QK+TF W+N HLMK+ K + D++ DLRDG L++LLEVLS KL + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI S +S D+S K+ LL W++K Y I NFS+ W DGK F ALIH+ RPDL+D++ + S ++NLE AF A++ LGV ++++ EDV DEKS++TYV+S+++ PK Sbjct: 62 LDPAERAVVRVADERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQIQSNRENLEQAFEVAER-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPK 299 HSP 3 Score: 101.293 bits (251), Expect = 4.406e-19 Identity = 161/832 (19.35%), Postives = 358/832 (43.03%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGLNKIYE---KFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSK----NDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLS------TMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLK-CANIDENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKA-VNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLIL----FVK---NGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKD---VPTNLDQLIS---AVTTSRQNQKDVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFESKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYEDIFKNYQNEIQNQIGGSNQDYFGYTKRSRIQNAHDWVSCE 4238 +W++E + + NDL + +E T+ E+ SV E ++ + +M +FH S L+T++ +L S +S +F+ K+ + W+ KE++++ W D+ + +S K+ F L ELE ++ L++ NH A ++ A ++S+ QW+ L C++ H++ A Y QFF +A + ++ + L + + ++ L E L ++ D E + K +V ++ S+++ L R + + ++VKAIC ++ + + L +NS W+V + P++C LI + +A A ++ + + LW +L + + L+S +D V+ W E + P ++++ L + D A + + + C F +L M ++ N+ A V ++ L+L++ K +Q S + + ++ + + + +LK+ ++ + + F++ +G S T L+ +L M++ + ++ + + + KLK+ +V + + + ++ E+ L +Q E+ PA ++ LE+ + T+ + ++KD V + LD+ IS AV ++ D+++ +++ ++ R+ + Q++ R S V + + WI +TT + ++ P +S+ + + + EI + + ++D+ K + + ++ YE Y+ +++Q Q G KR R+ ++ D ++ E Sbjct: 594 SWVEEMQMKLERAEWGNDLPSVELQWETQQHIHTSVEELGSSVKEARLY-----EGKMSQNFHTSYVETLGKLETQYCKLKETSSFRMRHLQSLHKFVSKATAELIWLNGKEEEELACDWSDS-NPNISAKKAYFSELTMELEGKQDVFRSLQDTAELLSLENHPAKQTVEAYSAAVQSQLQWMKQLCLCVEQHIKENAAYFQFFSDARDLESFLRNLQDSIKRKYTCDHNTSLSRLEDLLQDSMDEKEQLIQSKSSVASLVGRSKTIVQLKPRNPDHVLKSTLSVKAICDYRQ----IEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCLLIPPPNTEAIDVASRVEQSYQKVMALW--HQLHINTKSLISWNYLRKDIDAVQTWNLEKLRSSAPGECHQVMKNLQAHYEDFLQDSHDSALFSVADRLRIEEEVEACKTHFQQL---------MESMENEDKEETLAKVYISELKNIRLRLEECEQRLLKQIQ--SSASSKTDRDARQDVALRIAEQEHVQEDLKHLRSDLDAVSVKCTTFLQQSPSGSSATT-LRSELNLMVEKMDHVYGLSIVCLNKLKTIDVIVRSIQDAELLVKGYEIKL-SQEEAVPAD-------LSALESHRTTLQHWLSDVKDKNSVFSVLDEEISKAKAVAEQLHHRAAEPNLDLERYQEKGSQLQERWHRVIAQLETRQSEVESIQEVLRDYRACHGTLIKWIE--ETTAQQEMMKPGQAEDSRVLSEQLSQQTELFAEIERNQTKLDQCQKLSQQYSTTVKDYELQLMTYKAFVESQ-----QKSPG--KRRRMISSSDAITQE 1384
BLAST of Dystonin vs. UniProt/SwissProt
Match: sp|Q91ZU6|DYST_MOUSE (Dystonin OS=Mus musculus OX=10090 GN=Dst PE=1 SV=2) HSP 1 Score: 800.431 bits (2066), Expect = 0.000e+0 Identity = 566/1820 (31.10%), Postives = 972/1820 (53.41%), Query Frame = 3 Query: 14193 LVRENDSLTG----QVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSL------EKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKL-QIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWND-LKLIEDKFHEMTIHLTNSTIEDL-----NTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSK-KIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKT--PPL----IPIFDRSKRMETNQGISKIQEPLFV-----------NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGD--CECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF-----KFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSP------RIPQPVTSPRISQNIPSSRVSQSLASPRTP-----KVVASPGLQRKSRIPTRQTSQQGSQAS 19454 L E L G QV ER E L+NE S + LV D L V + L E +E E+ +R++ V + +T+K +I + +++ E+ D + ++ ++K+ + D + + ++L+ K ++L K+ I+ + K++ + + +S+K +D+V K+ ++ + + QL+ A L +F +Y L WL ET+ + Q L+ + L + ++E + L + KP +D + K+G L ++ + +G I A Y+ IKE +K RA L++ I +T+ ++K+DQ LE I +R+ S EK+ E++G + D++KLQ + L Q G E + R +KD ++ R ++ L+++ I S + + E + K+++++ LA +FW D + L+ +TI T I DL + V +++ E +R EID ++++ + G +LI P++ P V+++ +EL ++++ + + ++ ++ + ++ + +W N+L + P+ T+ V QI++ K+ K++ + ++E +N Q L K + K+ V L + W L + + RQH+L+ LL+LG+F A+DE + W+ T+ L+ K GD ++E+ LA+H +++ D+ Q++V + + ++I+ SS G EA+ +L L + W+++ E + +L+ AL++A F+G+ +++ + + + L K GGLP+TAKEQL M++ F + + ++ + +S I+ D+ L +KW++VK+ +K++LE+A+ FH + FINWLT E+ LN S I+ TIL Q++ H+ ++ SHRE+++ LDK THLKY SQK D+VLI+NL+ S+ RWEKVV R ER R+LD K AK+F + L++ + + + L+ + I P KI+ Q+ +HKEF +LG + YD+T R G L++K + D K+D ++ L+ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + A L+ S +DSS++ Q+ EL + W V L+ K+ RLE A QA EF + ++L E+ +++E LR P++E + + +I H F K L +++ G +L +P++ +IKH+I II++++ ++L+W++Q L L L ++ LL+ LL WL AE TL + + + E K EH+ F+ +MT KQ D D++ K++ PP IP+ D+ + G + F NP++N L SKW+QVW + L RR++L D ++ L+E+ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C+ +++ Q GD KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCRV H G + S+++ + AKGRTN ELREK G MA F + +P++ + T+A + + + P P +P R+P ++ S+ ++ + A RT K + PG + S+ +R +S++GS AS Sbjct: 5565 LSYETQGLKGEAASQVQERQKE-LKNEVRSNKALV-------DSLNEVSSALLELVPWRAREGLEKTIAEDNERYRLVSDTITQKVEEIDAAILRSQQFEQAADAELSWITETQKKLMSLGDIRLEQDQTSAQLQVQKAFTMDIL----RHKDIIDELVTSGHKIMTTSSEEEKQSMKKKLDKVLKKYDAVCQINSERHLQLERAQSLVSQFWETYEELWPWLTETQRIISQLPAPALEYETLRRQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSPK-EGIYIQEKYVAADTLYSQIKEDVKKRAVVLDEAISQSTQFHDKIDQILESLERIAERLRQPPSISAEVEKIKEQIGENKSVSVDMEKLQPLYETLRQRGEEMIA--RSEGTEKD----------VSARAVQDKLDQMVFIWGS---IHTLVEEREAKLLDVMELAEKFWCDHMSLV------VTIKDTQDFIRDLEDPGIDPSVVKQQQEAAEAIREEIDGLQEELDMVITLGSELIAACGEPDK-PIVKKSIDELNSAWDSLNKAWKDRVDRLEEAMQAAVQYQDGLQGIFDWVDIAGNKLATMSPIGTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEEADKHTVQDPLMELKLIWDSLDERIVSRQHKLEGALLALGQFQHALDELLAWLTHTKGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIE---SSEGEEASNLQYKLRILNQRWQDILEKTDQRKQQLDSALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNAHMEVCTAFAIKEETYKSLMLRGQQMLARCPRSAETNIDQDITNLKEKWESVKSKLNEKKTKLEEALHLAMNFHNSLQDFINWLTQAEQTLNVASRPSLILDTILFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDEARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKAQLVQHKEFQKSLGGKHSVYDTTNRTGRSLKEKTSLADDNLKLDNMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAED-QPVHGDIDLVMNLIDNHKVFQKELGKRTSSVQALKRSARELIEGSRDDSSWVRVQMQELSTRWETVCALSISKQTRLESALQQAEEFHSVVHTLLEWLAEAEQTLRFHGALPDDE--DALRTLIEQHKEFMKRLEEKRAELSKATGMGDALLAVCHPDSITTIKHWITIIQARFEEVLAWAKQHQQRLAGALAGLIAKQELLETLLAWLQWAETTLTEKDKEVIPQEIEEVKTLIAEHQTFMEEMTRKQPDVDKVTKTYKRRATDPPSLQSHIPVLDKGR-----AGRKRFPASGFYPSGSQTQIETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPITDADKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGSKMLRSESNSSITATQPTLAKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSASSHACQAASPPVPAAASTPKGTPIQGSKLRLPGYLSGKGFHSGEDSALITTAAARVRTQFAESRKTPSRPGSRAGSKAGSRASSRRGSDAS 7336 HSP 2 Score: 239.58 bits (610), Expect = 8.098e-61 Identity = 121/247 (48.99%), Postives = 169/247 (68.42%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI 1109 L + ++ R DERD +QK+TF WIN HLMK+ K V D++ DLRDG L++LLEVLS L + RFH L+N+ LD+L+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +S+D+S K+ LL W+++A E Y + ENF+T W+DGK F A+IHK RPDLID+ +++ S NLE AF A+K +GV ++++PEDV DEKS++TYV+SL++ PK + E I Sbjct: 19 LQAYEDVLERYKDERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKERLLLWTQQATEGYAGVRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPKVPEGGEGI 264 HSP 3 Score: 98.9821 bits (245), Expect = 1.901e-18 Identity = 91/467 (19.49%), Postives = 205/467 (43.90%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGL----------NKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSN 3182 NW+DE + + +DL + ++ E+F ++ E K + E +M + + + + L++++ +L + + F+ ++ + W+ KE+ ++ + W + S ++ K+ L+ ELE +E SI + L + NH A I+ A ++++W WIL L C++ H++ + Y +FF +A EA + + L + + ++ + + E L +E + E ++ Y+ V ++ +++V L R + + +KAIC ++ + + E + L NNS W+V + P++CF + + +A A ++ + + LW + + ++ V L++ +D ++ + P Q+++ L + D + + I ++I++ ++ C + EL S+ Q +V N Sbjct: 613 NWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAK--ISEIQMT------APLKLSYTDKLHRLESQYAKLLNTSRNQERHLDTLHNFVTRATNELIWLNEKEESEVAYDWSERNS-SVARKKSYHAELMRELEQKEESIKAVQEIAEQLLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIQENSAYFEFFNDAKEATDYLRNLKDAIQRKYSCDRSSSIHKLEDLVQESMEKEELLQ-YRSVVAGLMGRAKTVVQLKPRNPDNPLKTSIPIKAICDYRQ---IEITIYKDDECV-LANNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDFANRIEQQYQSVLTLWHESHINMKSVVSWHYLVNEIDRIRASNVASIKTMLPGEHQQVLSNLQSRLEDFLEDSQESQIFSGSDISQLEKEVSVCRKYYQELLKSAEREEQEESVYN 1065 HSP 4 Score: 79.337 bits (194), Expect = 1.745e-12 Identity = 87/430 (20.23%), Postives = 197/430 (45.81%), Query Frame = 3 Query: 12426 EMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKS------EVENLAEQKIETAEKSMHKID---NLAAINE---KIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIG-------AFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQND----DSSIDESI 13646 + E + + LS + +K +L +K ++ Q +RE F + +LD + D LR++ ++ L L++ + + T E S I +L A+++ K+++ R+ + + + EF K +F + +A E + ++ I F +++++PL+ + +++ +G + + + +E ++DSV + L + V+ + + L+ +F +LE+L ++ + + ++ PS E+ K+Q+ +LL L+ R+S+++ + + G + + + + +L +L L++++E LL+ AE +N + + +++ F + EP WL EK LAN + T A ++E++I ++K LQ D S+D+++ Sbjct: 5075 QAETLAEEHSELSQQVDEKCSFLETK----------LQGLGHFQNTIREMFSQFTECDDELDGMAPVGRDAETLRKQKACMQTFLKKLEALMASNDSANRTCKMMLATEETSPDLIGVKRDLEALSKQCNKLLDRAKTREEQVDGATEKLEEFHRKLEEFSTLLQKAEEHEESQGPVGTETETINQQLDVFKVFQKEEIEPLQVKQQDVNWLGQGLIQSAAANTCTQGLEHDLDSVNSRWKTLNKKVAQRTSQLQEALLHCGRFQDALESLLSWMADTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLEDRKSTVEVIKREGEKIAASAEPADRVKLTRQLSLLDSRWEALLSRAEARNRQLEGISVVAQEFHETLEPLNEWLTAVEKKLANSEPIGT-QAPKLEEQISQHKALQEDILLRKQSVDQAL 5493 HSP 5 Score: 61.2326 bits (147), Expect = 5.773e-7 Identity = 55/246 (22.36%), Postives = 113/246 (45.93%), Query Frame = 3 Query: 15855 WFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKF-SGGLPDTAKEQLK 16589 W + + P E + V QIQ+ K L+ +E + +E+I + G ++ + P + ++ L+ ++ W LL R QL+ I + EFH ++ EW+ A E L N + LE ++QHK ++ D+ + + SV + E++K+ +LE ++ ++++ + + LE AL+ A +E+ +D++ ++E+ + + GL A Q++ Sbjct: 5338 WMADTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLEDRKSTVEVIKREGEKIAASAEPADRVKLTRQLSLLDSRWEALLSRAEARNRQLEGISVVAQEFHETLEPLNEWLTAVEKKLANSEPIGTQAPKLEEQISQHKALQEDILLRKQSVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSADVAKTLEHALQLAGQLQSMHKELCNWLDKV--EVELLSYETQGLKGEAASQVQ 5581
BLAST of Dystonin vs. UniProt/SwissProt
Match: sp|Q9UPN3|MACF1_HUMAN (Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4) HSP 1 Score: 780.015 bits (2013), Expect = 0.000e+0 Identity = 603/2138 (28.20%), Postives = 1070/2138 (50.05%), Query Frame = 3 Query: 13305 QSSLDELNKAGSDLLINT-KEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQN--DD--SSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPY--QTRDIWEESLNLVKEVKSHEETL---KNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVREND----SLTGQ--VGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSL------EKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMS------DQINNDYSELEECKIDFTNLLSAWNE---QKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNE---KVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSP------SRKNANDKDDSV-EISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLG-YQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTF-PKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPI-QDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKT--PPLIPIFDRSKRMETNQGISKIQEPLFV--------NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF-----KFKPAT---------------LPIPTKKPTTAKIPSPRVSQ-PLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRT-PKVVAS-PGLQRKSRIPTRQTSQQGSQAS 19454 Q L ++N G L+ + K+ L+++++E+NA++ L + + A+ F+D EP L WL E+ +AN P+ + ++ +IQE K LQ DD +++D ++ G +++ + + KI + K K + Q + + + F S + KL +P QT I ++ +++ +EE + KN+DQ G+ L + ++ + I K++ + + +I+V++ K L E + +A +F LT +RE + + GQ GE+ + + ++K V + R LD + V L E ++ + + +++K V + + ++ +I + +++ E+ D + ++ ++K+ + DQ + ID + +E + I T + +K + L+ + + +Q E+ + + +L+ A L +F +Y L W+ ET + Q +D +QL + ++E++ L S + KP +D ++K G L ++ N +G+ + + A+ Y IKE ++ RA L++ + +T++ E K++ LEN+ R+ P + P ++D+ E + D + ++KLQ E R DKD + EI D + + E+ ++++ E + K +++L LA +FW D+ + TI T + DL + ++ + + E ++ E D +++ I G LI E P+V ++ +E+ +E + + ++++ ++ + ++ + +W +L + P+ T+ V Q+ + KE K ++ + ++E +N G L K + ++ + L + W L + + RQH+L+ LL+LG+F A++E + W+ TE L + GD +E+ LA+H +++ D+ QA+V + + E+++ SS G +A+ RLE + + WE + + + +L+ L++A F+ + ++ + + S+L K +GGLP+TA+EQL M++Y K + + + + G E + +L +KW V + E RKS+LE+A+ F + +FINWLTL E++LN P S I++T+L Q+E H+ ++ +HR++++ LD+ LK++SQK D+VLI+NL+ S+ RWEKVV RS ER R+LD K AK+F + + L+D + L+ + I P KI+ Q++KHKEF LG YD+T R G L++K + +DS+K+D + ++ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + L+ S +D+++++ QL EL + W+ V KL+ K+ RLE+A QA F + L E+ S++E LR P++ E + ++I H F K + + +N G IL +P+ +IKH+I II++++ ++L+W++Q L+ L L LL++LL W+ AE TL+ + + + K EH+ F+ +MT KQ D D + K+K P P ++S R + +S+ P NP+INQL ++W+QVW + L R+++L D ++ L+E++ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF TT++EM VADIFD++ G+IDY +F+AAL P+++ Y +P + + I DEV +Q+++C C+ +++ Q G+ KY+FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR A+GRTN ELREK P+G M PF + KP++ T P++ P+ P S ++ +P +P TS + SS S + R PK AS PG + SR +R +S++GS AS Sbjct: 5288 QMKLQQVNGLGQGLIQSAGKDCDVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIAN-QKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVD--------MLQAEGGRIAQSAELADREKITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEK-KLANSEPVGTQTAKIQQQ---IIRHKALNEEIVNRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKF-------QSTYEELTGWLREVEEELATSGGQSPTGEQ-IPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKLVSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEEQKTV----------LQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKPHIDKLLKIGPQLKEL-NPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRL---RMPPLIPAEVDK----IRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWED--------------IKARAEEREIKFLDVLELAEKFWYDMAALL-----TTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGE-TEKPEVRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLE---SSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAED-QPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDT--EALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALIAEHQTFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKS-RSGGRKSLSQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAY--RPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------ARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRP--TPTFHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDAS 7333 HSP 2 Score: 248.825 bits (634), Expect = 1.169e-63 Identity = 124/247 (50.20%), Postives = 170/247 (68.83%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI 1109 LDP +R V+RVADERD +QK+TF W+N HLMK+ K + D++ DLRDG L++LLEVLS KL + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI S +S D+S K+ LL W++K Y I NFS+ W DGK F ALIH+ RPDL+D++ + S ++NLE AF A++ LGV ++++ EDV DEKS++TYV+S+++ PK + E I Sbjct: 62 LDPAERAVVRVADERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQIQSNRENLEQAFEVAER-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKVPEGGEGI 307 HSP 3 Score: 106.301 bits (264), Expect = 1.187e-20 Identity = 161/832 (19.35%), Postives = 362/832 (43.51%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGLN---KIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKND----LKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLS------TMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANI-DENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVN------DLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKD---VPTNLDQLISAVTTSRQNQKDVSYE---DIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGL--QTTVKSQINVPNNVFESKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYEDIFKNYQNEIQNQIGGSNQDYFGYTKRSRIQNAHDWVSCE 4238 +W++E + + NDL + + + T+ E+ SV E ++ + +M +FH S + L+T++ +L S +S +F+ ++ + W+ KE++++ + W D S +S K+ F L ELE ++ L++ NH A ++ A ++S+ QW+ L C++ H++ Y QFF +A E ++ + L + + ++ L E L ++ D E + K +V ++ S+++ L R+ + + ++VKA+C ++ + + L +NS W+V + P++CFLI + A + A ++ + + LW +L + + L+S +DLV+ W E + P +I++ L + D + + + + + + C ARF L S + TV+ S +K ++ L+L++ K +Q S+ + ++ + + + +L+ ++ D L S L+ +L +++ + ++ + +++ KLK+ +V + + + ++ E+ L +Q E A ++ LEA T+ + ++KD V + LD+ I+ + ++ E D+++ +++ ++ R+ + Q++ R S + E + LG + +A +I +TT + ++ P +S+ + + + EI + + ++D+ K + + +++ YE Y+ +++Q Q G KR R+ ++ D ++ E Sbjct: 594 SWVEEMQMKLERAEWGNDLPSVELQLETQQHIHTSVEELGSSVKEARLY-----EGKMSQNFHTSYAETLGKLETQYCKLKETSSFRMRHLQSLHKFVSRATAELIWLNEKEEEELAYDWSDNNS-NISAKRNYFSELTMELEEKQDVFRSLQDTAELLSLENHPAKQTVEAYSAAVQSQLQWMKQLCLCVEQHVKENTAYFQFFSDARELESFLRNLQDSIKRKYSCDHNTSLSRLEDLLQDSMDEKEQLIQSKSSVASLVGRSKTIVQLKPRSPDHVLKNTISVKAVCDYRQ----IEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNKDAIEMASRVEQSYQKVMALW--HQLHVNTKSLISWNYLRKDLDLVQTWNLEKLRSSAPGECHQIMKNLQAHYEDFLQDSRDSVLFSVADRLRLEEEVEACKARFQHLMKSMENEDKEETVAKMYISELK--------NIRLRLEEYEQRVVKRIQ--SLASSRTDRDAWQDNALRIAEQEHTQEDLQQLRSDLDAVSMKCDSFLHQSPSSSSVPTLRSELNLLVEKMDHVYGLSTVYLNKLKTVDVIVRSIQDAELLVKGYEIKL-SQEEVVLAD-------LSALEAHWSTLRHWLSDVKDKNSVFSVLDEEIAKAKVVAEQMSRLTPERNLDLERYQEKGSQLQERWHRVIAQLEIRQSEL-ESIQEVLG---DYRACHGTLIKWIEETTAQQEMMKPGQAEDSRVLSEQLSQQTALFAEIERNQTKLDQCQKFSQQYSTIVKDYELQLMTYKAFVESQ-----QKSPG--KRRRMLSSSDAITQE 1384 HSP 4 Score: 95.9005 bits (237), Expect = 1.644e-17 Identity = 267/1437 (18.58%), Postives = 590/1437 (41.06%), Query Frame = 3 Query: 12831 KIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEE---LIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDI----ENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKII------INKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDL--KQISSENDSAA--INCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVR--ENDSLTGQVGERNMEILEN---ETNSVEK-------------LVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCM-EVLSNFEQKINEMS------DQINNDYSELEECKIDFTNL---LSAWNEQKESI--NSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIED---LRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLT-KGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEII---KEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDT--------VKNLAETRKSRLEKAI-ETVETFHLDMGKFINWLTLTEKNLNQ--QRPVSRIVSTILEQVEAHRALKRDIT 16946 ++ T+F+S + + E + + + T + I F +Q+ LKK++ E ++D N+ ++ + ++ E +D + + ++VSD + +D + + Q+++ + + +V R L A +E ++ +QL + + + + S+DEL S++ E +K+ LQ + + L +YE + L + R +RA L F + YE W++ +A SP +D ++ ++ +E + L+ + I KL I +N +G E + K ++ + E + L+ + + + D++ +TL S ++ L + + R+ ++ + E++ + + + L + GE+L + ++ D AA I K++ + ++++I A ++ F + + +AE+F L + +V E+ + + ++ +E E ET+ + + C + KS+D N+ E + + E ++ ++ + +A +Q ++ Q M + L N K+ M + + + +E++E K++ + N Q E + +T + +IR+ P ++LK L E+ + + +Q +L+ A+ +F + L WL TEE + + + DP + + L N + ++ + K+G+ L + ++ + +E + + ++ + + R L+ + + +++ +L + +++ S PE E+L E+ L + ++L R +DDS S + + +A + + S+ E K K+ L+LA EF N L ++ + +T+ + I + +N IE+ E++ H I ++ Q G QL + ++ + ++ ++ +E V ++ ++D + + E KL +W ++ + L + + + Q+ K KE + + K + + G L K P ++++ L + D W + +RQH+L+ LL G+F A+ ++W+ E L + HGD++ + + HK+ + ++ +V ++R E+I ++D + + + L++L W+ + + + +K LE ALK+A +F + + ++ L + +F G LPD E L+ +D ++ F K + + + I D +K W T V A+ + RLE A+ E V L + + + W+ E L Q Q P+ + + + + H+ ++T Sbjct: 5562 QLATKFQSTYEELTGWLREVEEELATSGGQSPTGEQIPQF-QQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREG-LDKLVSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEEQKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQL-PSPAIDHEQLRQQQEEMRQLRESIAEHKPHIDKLLKIGPQLKELNPEEGEMVE----EKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERLEKLEDAM---------------QAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIRE-PLTELKHL----------WENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAREQLDTHMELYSQLKAKEETYNQL------LDKGRLMLLSRDDSGSGSKT-----------EQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSL---QEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQL-KFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDDTTWVKGQ----LQELSTRWDTVCKLSVSKQSRLEQALKQAEVF---RDTVHMLLEWLSEAEQTLRFRGALPDDT-EALQSLIDTHKEFMK----KVEEKRVDVNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAEL-LEELLAWIQWAETTLIQRDQEPIPQNIDRVKALIAEHQTFMEEMT 6931
BLAST of Dystonin vs. UniProt/SwissProt
Match: sp|Q9QXZ0|MACF1_MOUSE (Microtubule-actin cross-linking factor 1 OS=Mus musculus OX=10090 GN=Macf1 PE=1 SV=2) HSP 1 Score: 768.074 bits (1982), Expect = 0.000e+0 Identity = 601/2150 (27.95%), Postives = 1074/2150 (49.95%), Query Frame = 3 Query: 13287 DRLKKRQSSLDELNKAGSDLLINTKEPKKSQ-LQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQN--DD--SSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPY--QTRDIWEESLNLVKEVKSHEETL---KNLDQV---GEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERN-----MEILENETNSVEKLVCQARNDLDKLKSVDAFENSL------EKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMS------DQINNDYSELEECKIDFTNLLSAWNE---QKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSP------SRKNANDKDDSV-EISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLG-YQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTF-PKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQ-DSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKT--PPLIPIFDRSK---RMETNQGISKIQEPLFV-------NPKINQLHSKWKQVWFMILNRRKRL---LDHIEYL-KEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF-----KFKPAT---------LPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVT-SPRIS-----QNIPSSRVSQSLASPRTPKVVAS-PGLQRKSRIPTRQTSQQGSQAS 19454 D++ Q L ++N G L+ + + Q L++++DE+N ++ L + + A+ F+D EP L WL E+ +AN P+ + ++ +IQE K LQ DD +++D ++ G +++ + + KI + K K + Q + + + F S + KL +P QT I ++ +++ +EE + KN+DQ G+ L + ++ + I K++ + + +I++++ K L E + +A +F LT +RE + G ++ + + ++K V + R LD + V L E ++ + + +++K + + V ++ +I + +++ E+ D + ++ ++K+ + DQ + ID + +E + I ST + +K + L+ + + +Q E+ + + +L+ A L +F +Y L W ET + Q +D +QL + ++E++ L S + KP +D I+K G L ++ N +GK + + A+ Y IK+ ++ RA L++ + + + ++K++ LEN+ R+ P + P ++D+ E + D + ++KLQ E R DKD + EI D + + E+ +++++ E + K +++L LA +FW D+ + TI T + DL + ++ + + E ++ E D +++ I G LI E P+V+++ +E+ +E + + ++++ ++ + ++ + +W +L + P+ T+ V Q+ + KE K ++ + ++E +N G L K + ++ + L + W L + + RQH+L+ LL+LG+F A++E + W+ TE L + GD +E+ LA+H +++ D+ QA+V+ + + +E+++ SS G +A+ RLE + + WE + + + +L+ L++A F+ + ++ ++ + ++L K +GGLP+TA+EQL M+++ K I + + + + G E + +L +KW V + E RKS+LE+A+ F + +FINWLTL E++LN P S I++T+L Q+E H+ ++ HR++++ LD+ LK++SQK D+VLI+NL+ S+ RWEKVV RS ER R+LD K AK+F + + L+D + L+ + I P KI+ Q++KHKEF LG YD+T R G L++K + D++K+D ++ ++ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + L+ S +D+++++ QL EL + W+ V KL+ K+ RLE+A QA EF + L E+ S++E LR P++ E + ++I H F K + + +N G IL +P+ +IKH+I II++++ ++L+W++Q L+ L L LL++LL W+ AE TL+ + + + K EH+ F+ +MT KQ D D + K+K+ P P ++S+ R NQ P+ + NP+INQL ++W+QVW + L R+++L LD +E L E++ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF TT++EM VADIFD++ G+IDY +F+AAL P+++ Y +P + + I DEV +Q+++C C+ +++ Q G+ KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR A+GRTN ELREK P+G M PF + KP++ + +PS + + I S + P P S R S N S + + A+ PK AS PG + SR +R +S++GS AS Sbjct: 5241 DQVDPLQVKLQQVNGLGQGLIQSAGKNCDVQGLEHDMDEINTRWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLTDTEELIAN-QKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVD--------MLQAEGGRIAQSAELADREKITGQLESLERRWTDLLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTAN-KLANSEPVGTQTAKIHQQ---IIRHKALNEEIINRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITLTSSKALRTLEQARQLATKF-------HSTYEELTGWLREAEEELAASGGQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSHALLELVPWRAREGLDKLVSDANEQYKLISDTVGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRGEIFSTCGEEQKAV----------LQEKTECLIQQYEAVSLLNSERYARLERAQVLVNQFWETYEELSPWAEETLALIAQLPPPAVDHEQLRQQQEEMRQLRESIAEHKPHIDKILKIGPQLKEL-NPEEGKMVEEKYQKAENMYAQIKDEVRQRALALDEAVSQSAQFHDKIEPMLETLENLSSRL---RMPPLIPAEVDK----IRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWED--------------IKARSEEREIKFLDVLELAEKFWYDMAALL-----TTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGE-TEKPEVKKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVATVNKAGSELLE---SSAGDDASSLRSRLETMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELNRMENQLSASKPTGGLPETAREQLDTHMELHSQLRAKEEIYNQLLDKGRLMLLSRGDSGSGSKTEQSVALLEQKWHAVSSKVEERKSKLEEALSLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNDHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLAGDTQKLDNLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAE-DQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIEGSRDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEEFRDTVHMLLEWLSEAEQTLRFRGALPDD--TEALQSLIDTHKEFMKKVEEKRVDVNTAVAMGEAILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALITEHQSFMEEMTRKQPDVDRVTKTYKRKSVEPTHAPFMEKSRSGSRKSLNQPTPP---PMPILSQSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELCPELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAY--RPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------ARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVISSSGSKLKRPTPAFHSSRTSLAGDTSNSSSPASTGAKANRADPKKSASRPGSRAGSRAGSRASSRRGSDAS 7299 HSP 2 Score: 248.44 bits (633), Expect = 1.476e-63 Identity = 123/247 (49.80%), Postives = 170/247 (68.83%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI 1109 LDP +R V+RVADERD +QK+TF W+N HLMK+ K + D++ DLRDG L++LLEVLS KL + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI S +S D+S K+ LL W++K Y + NFS+ W DGK F ALIH+ RPDL+D++ + S ++NLE AF A++ LGV ++++ EDV DEKS++TYV+S+++ PK + E I Sbjct: 62 LDPAERAVVRVADERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGVKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQVQSNRENLEQAFEVAER-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKVPEGGEGI 307 HSP 3 Score: 112.464 bits (280), Expect = 1.972e-22 Identity = 161/837 (19.24%), Postives = 366/837 (43.73%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGLN---KIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSK----NDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLS------TMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLK-CANIDENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDL-QLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQ-----VCKHKEFETNLKNYEPQVNDLIL----FVK---NGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKD---VPTNLDQLISAVTTSRQNQKDVSYE---DIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFESKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYEDIFKNYQNEIQNQIGGSNQDYFGYTKRSRIQNAHDWVSCE 4238 +W++E + + NDL + + + T+ E+ SV E ++ + +M +FH S L+T++ +L S +S +F+ ++ + W+ KE++++ W D+ +S K+ F L ELE ++ L++ NH A ++ A ++S+ QW+ L C++ H++ A Y QFF +A + ++ + L + + ++ L E L ++ D E + K +V ++ S+++ L R + + ++VKAIC ++ + + L +NS W+V + P++CFLI + +A + A ++ + + LW +L + + L+S +D V+ W+ E +L P ++++ L + D A + + + C A F L M+++ N+ E+ V + +L ++ + + Q L ++ SP D Q + + + + +L++ ++ + + F++ +G S T L+ +L M++ + ++ + +++ KLK+ +V + + + ++ E+ L +Q E+ PA ++ LE+ + T+ + ++KD V + LD+ I+ + + + E D+++ +++ ++ R+ + Q++ R S V + + WI +TT + ++ P +S+ + + + EI + + ++D+ K + + +++ YE Y+ +++Q Q G KR R+ ++ D ++ E Sbjct: 594 SWVEEMQMKLERAEWGNDLPSVELQLETQQHIHTSVEELGSSVKEARLY-----EGKMSQNFHTSYVETLGKLETQYCKLKETSSFRMRHLQSLHKFVSRATAELIWLNGKEEEELACDWSDSNP-NISAKKTYFSELTMELEGKQDVFRSLQDTAEVLSLENHPAKQTVEAYSAAVQSQLQWMKQLCLCVEQHVKENAAYFQFFSDARDLESFLRNLQDSIKRKYTCDRSTSLSRLEDLLQDSMDEKEQLIQSKSSVASLVGRSKTIVQLKPRNPDHVLKSTLSVKAICDYRQ----IEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNKEAIEMASRVEQSYQKVMALW--HQLHINTKSLISWNYLRKDLDTVQTWSLEKLRSLAPGECHQVMKNLQAHYEDFLQDSHDSALFSVADRLRIEEEVEACKAHFQHL---------MKSLENED-------KEETLAKVYISELKNIRLLLEECEQRLLKQIQSPASSKTDRDARQDITLRIAEQEHTQEDLQHLRSDLDAISMKCNVFLQQSPSGSSATT-LRSELNLMVEKMDHVYGLSTVYLNKLKTIDVIVRSMQDAELLVKGYEIKL-SQEEAVPAD-------LSALESHRTTLQHWLSDVKDKNSVFSVLDEEITKAKKVAEQLRHPASEPNLDLERYQEKGSQLQERWHRVIAQLETRQSEVESIQEVLRDYRACHGTLIKWI--EETTAQQEMMKPGQAEDSRVLSEQLSQQTELFAEIERNQTKLDQCQKFSQQYSTIVKDYELQLMTYKAFVESQ-----QKSPG--KRRRMISSSDAITQE 1384 HSP 4 Score: 70.8626 bits (172), Expect = 6.888e-10 Identity = 92/480 (19.17%), Postives = 210/480 (43.75%), Query Frame = 3 Query: 12312 IKTTQSDMHLIKPDMENTKLLIASIAQISP--VNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINE---KIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAK--------------LLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQ----NDDSSIDESIKKLKIIINKVDG 13682 +K Q + ++P ++ + + + +P +A+ L + E + + ++ + + +K + + + R+ ++ +L +++D D DSL+ QI D+ + + + + ++E + E++ + + L A+N+ K+ E RQ L L V DF RK+ N+ A+ ++N + F + +VDPL+ +L+++ +G + + +E +MD + ++ L + V+ + L+ KF +LE L ++ + + ++ PS EY K+Q+ +LL L R++++D L G + + + + ++ +L+ L ++ +LL+ A + + + + L+K F + EP +L LAN + T A ++ ++I +K L N ++D++IK + ++ + G Sbjct: 5016 LKAQQEVLQALEPQVDYLRNFTQGLVEDAPDGSDASPLVHQAEVAQQEFLEVKQRVSSSCLTMENKLEGIGQFHCRVREMFSQLADLDDELDGMGAIGRDTDSLQSQIEDVRLFLNKIQALRFDIEDSEAECRKMLEEEGTLDLLGLKR--ELEALNKQCGKLTERGKVRQEQLELTLGRV-------EDFYRKLKALNDAATAAEEGEALQWIVGTEVDVINQQLADFKLFQKDQVDPLQVKLQQVNGLGQGLIQSAGKNCDVQGLEHDMDEINTRWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLTDTEELIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQLESLERRWTDLLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTANKLANSEPVGTQTA-KIHQQIIRHKALNEEIINRKKNVDQAIKNGQALLKQTTG 5485 HSP 5 Score: 60.8474 bits (146), Expect = 6.019e-7 Identity = 120/614 (19.54%), Postives = 266/614 (43.32%), Query Frame = 3 Query: 16068 INDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSL--TNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRL-EQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGL---PDTAKEQ----LKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLK-YISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMN---RTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKI--DEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQ---TLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQF 17852 +N + +L + L +RQ LQ + + E + ++W+ + E L + + +++ +K A++ + + K++ A ++K +S E +++ E L WE+ E A+ +LE++ F + ++ + E K M G L P+ K+Q LK F + +LN + + ++S +SQ + D++ + +KW + + +R S++++AI + + + + L+ Q +S + +Q+E ++ D+ E+ + L I +++ ++ + ++ + + +++R L ++F+ M RT LD+ S ++ I +++ Q+ +++EF NL H+ +Y+ G L P + KK +++V L+ W+ L K+ R+ L D + + Y+ + +L+ W+ + K+S+ ++ VQ +LL ++L + R ++E +N+ A L+ SE D I D+ A L + + + K LEE + EF+ + ++++ ++H+L F Sbjct: 4404 VNSKYEKLWEVLRERQESLQTVFSRMEEVQKEASSVLQWLESKEEVLKAMDATLSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLKTYPNSQEAENWKKMQEDLNSRWEKATEVTVARQKQLEESASHLACFQAAESQLRPWLME---KELMMGVLGPLSIDPNMLKQQVQFMLKEFEARRQQHEQLNEAAQGILTGPGDMSPSASQ-----VHKDLQSISQKWVELTDKLNSRSSQIDQAIVKSTQYQDLLQDLSEKVKAIGQRLSGQSAISTQPEAVKQQLEETSEIRSDLGQLDNEIKEAQTLCQELSLLIGEQYLKDELKKRLETVALPLQGLEDLAADRMNRLQAALASTQQFQQMFDELRTWLDEKQSQ---QAKNCPISAKLERLQCQLQENEEFQKNLNQHSGSYEVIVAEGEALLLSVPPGEEKKTLQNQLV-ELRSHWEDLSKKTANRQSRLKDCMQKAQKYQGHVEDLVPWIDECKSKMSELQV----TLDPVQLESSLLRSKAML-NEAEKRRSLLEILNSAADILINSSEIDEDEIRDEKAGLNQNMDAITEELQAKTSSLEEMTQRLKEFQESFKNIEKKVEGAKHQLEIF 5000
BLAST of Dystonin vs. TrEMBL
Match: A0A1E1XFA6 (Putative ca2+-binding actin-bundling protein (Fragment) OS=Amblyomma aureolatum OX=187763 PE=2 SV=1) HSP 1 Score: 1001.89 bits (2589), Expect = 0.000e+0 Identity = 840/3346 (25.10%), Postives = 1587/3346 (47.43%), Query Frame = 3 Query: 9471 EIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYE----------MKQRDM-----EQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQXXXXXXXXXXXXXXADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAAL---LNKC-------LSFDQEY---------KEFSDKLDSELNELLSVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSM----SPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEE-------IQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLS-LEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLEC-TGKSIENKHQQINDLKNLISPXXXXXXXXXXXXXXXXXXXXESXXXXXXXXXXXXXXXXXXXQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNA--TLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQK-IETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANND-----PELAKL--LNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYG---FESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKL----DLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQ-NKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQIT-NIDRQQSLITKLEEMR------MKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ-RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWL-RAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALM-IQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEI--ITNSKKKTP-----------PLIPIFDRSKRMETNQGISKIQ---------EPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETY-----QVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKK 19202 E QR ++ SL + ++EQ + + +EI ++P ++ +N+++R+ P L K++ KL +N K+ D G V SC D F + N +F+E L + + E M QR++ E + + L ++ + D + ++ LE+ W L EL++ R ++ R Y L+ +++ L E L PLA+D L Q +I+ + E ++ ++G YD++ ++ S R P++ + +P + + T D + Q+ SE + RY +G +L +R+ + +L L C ++F + +E +D+ S+L EL E++ L + +LLR R PG L+++LD L ++ L+ + + L L +K+F + + N +V+K++M VLGP+ T AQ QQV + DE+ E ++ L GQE++ + PT + E LD + + + L++RE + + G S +F + + D L + + ++ + + D E ++ L++ + L E+E ++ L E +SD + E++ ++ + + + KI++ + + + + ++WL + QL+LL L++ L + + + + K+ +V + ++ M S +++Q+ +L L + + + + Q+A + K N NK W+ + +++ + + E + E T K+ ++H Q D + + + + S + L E+ L ++ ++ E L L +LE K + E+A + P + +L+ + ++ ++ + + +P + + + +++ +V R+Q L++ L + L + + + ++++ L E++++ + D+ ++ QI + + + + + N + E + L Q + A+ + ++++L ++ E R SL + +F + R++ A + P A + L + + F + V+PL ++++ + GN + G+ +E+++D + +++L + V + E ++ L++ KF +L + ++E+ + + PS +Y K+QL + L L RQ S+ L GS+++ + KS +Q +L +L+ +++ L A+ + +R + +++SF++ P + WL+ E+ L T PT DA + +R QE++ L D + + L ++ + ++ + + + +L DR Y + + L FED L ES + ++ V + ++ ++E L +EV H++ + L G++L + +S ND+ + +++ L + +++ A ++L ++P+A+ F A+ +L D L AL E +LT Q E M+ LE E + + V + N L + VE + +RF + ++ ++A ++ +R ++ +L+ ++ E+++ + + I + L + L + QK + ++ +KK+ R+ P D +++ + ++ S +A + L++A+PLA+ + +++ L WL E E + P + + ++ +AL + + KPLLD + K+G L+++ + + +RYN +++ ++ + LE+ + ++ +K+D + L + D++ ++ S HPE++ E++ ++ DL K ++ +Q K D++ SV + +KL +++ + +Q + + L++A FW +L + ++ +L + + ++++ +++++ +++ E+D ++ + Q G+ L++ P+ E+KR+ E + S+ E T R+Q+LI L++ L E+ + LGP+ + V QI + ++ K +++P ++E +N+ +L++ + + L IN W LL GL +RQ +L+ LL LG+F A+ E + W+ TE +L + GD +E+ LA+HK++ D+ Q+SV + R ++I+ D S TQ +L L + W+ L++ A + +LE AL+EA F + Q++ + ++ +L K GGLP+TA+EQL RFM++Y ++E +++ E ++ + S G ++ + L ++WD V A RK +LE A++ FH + +F+ WLT EK+L RPVSRI+ +L Q+E H++ ++D+ +HRE ML LDK THLKY SQK D++LI+NL+ S+ HRWE+VVS+++ER+R LD+GYKEAK F D L + + L+ G P KIR + +H+EF LG YD+ R G LR++ P D + + L+ KW +LCNKS++R++ L +ALL SG +KDA+ L+ WL RA+ +D + GD++TV L+ +H + +L+ R +E + A L+ S +D++ I Q++ L+S W +V+KL++ K+R+LEEA QA + + + L E+ S +E +LR P E E + H F + + E EIL +P+A I+H++ II+S+W ++ W+ QR L +HL L + LL++LL WL AAE +L+ E++ L + + +H RF+ DM+ +Q D D I SK++ P P DR +Q + EP +P+ +L KW+ VW + + R++RLL+H++YL+E+E++KNF+F++WRRR++ WMN+ KSRVMD FR+ D D+DG+VT+++FIDGI+ SKF T+R+EME VADIFD+ G+ID+++++ LRPDR+ Q KP E E I DEV++Q++KCTC + +K+ Q G+GKY+FG+++KLRLVRILRS VMVR+GGGW ALDEFLVK+DPCR AKGRTN ELRE+ +G +M PFK K + P K Sbjct: 1593 EATQRGQSAKLASLVRERLDEQIHEHRVLRSEIDGQRPAIDA--LNSSARDLPGNARLAKKVEAKLKDINNRFEKILDKSTRRGELLDEVSSCLD------------QFNSMAN-RFEEWLASVLQAVEGEEQPRLEHAMNQRNLRKDEFEDLLRAGRALCAKRDVTDTGPVRDKVKQLEQQWKELGELLSERERQGRQRSEQGAAYETLRQQVLSWLQTTEGRLEALGPLALDRDILRRQAAEIKPLVKEHAEYASTMDRVNELGRSYDAL------------RVDSRSRPPARKGGSPHKEPYANGASTH-----------------------DLSPVQQQLSE-------MNHRYHLLGVRLSDRQQEADSLSEELRTCTEAIRTLVTFLKSRSVPRDLPSSRELADQQLSQLREL-QTELQERQLE-------------------VDRARLQAHELLRRRPQAPGADALQTQLDELLSRWQGLQGALRSRLLL----IQLLKEFQDTHDLLNNWLVQKDKMFQVLGPIATEPRLVAAQTQQVLCMRDELTSQEPLLRRLTTCGQELLNQLDDKDGPTGRR---LREQLDSIRRHWAEMVSRLEERERALGAATGASAEFQAALARLLDSLQGVGDDFER----LSEAGDCEAQLRHLAALEERLEAQRPPLAEAEARAENLCELLSDAASRSEVRARLGSAQKLYNGLSRKINNRKAELESSLKEDRGFFSNCDSIQEWL--RSIQLSLLPDLKISADTDILHKQVTEFEPAYKSLLDKEHEVHLVLSKGADMVTRMSRKQEAQQLRTRLDGLRRSWDQLRKEATDRHTRLQRAFENCKKFNATFNKFGPWLQSAEGRLSSLVLTNYQRTEVERQAKELQTFKNDLSRHSQEYDTVRNLGETFLAGCDVDKEGVKKDLDTLRSRWEKLNQSVSERSRQLDEVTGKLCEFQEKAGELGHGLQRLEDKLASHDALGEAA-RNPRLLDRLQGMAREADE----LRRGLDRLRAFTDTWLASAPADCDTSHVRGQLDALVRRHQQLANDLQDRCGQLEAAGTVVAQYHAKVKTAQQDLSGLEEELESMGPIARDIKTVRTQIDQVKSFQGRLSSAAHEVDNAEHECQELISQGYTQDAKGARSQVESLRRQLSRLEERARGRHTSLEAMLAKLEKFYEDLHSTQRRVGSALGEEHTFRPVAADVESLRSQQEQFKQFRKNHVEPLGREVDGVNRAGNALIQSASPGVNTTVLERDIDKLNDEWNQLKEKVGERERLLEGALLQSGKFQEALAGVARWLEDTEELVANQRPPSADYKVLKAQLQEQKFLNKLLLDRQGSMGSLQAMGSEVMRHLSPADKSHVQAQLHDLSQRFDRLTRGAQERTAALERTLPVARSFQEQLSPLVEWLEQTERRLTAMSTLPT-DADRLAQRAQEHRDLHRDVLGHKRAFEALTETAQQLMSLVGDDEAQAVVDSLQELTDR---YARLVGDSERLEQLLAEARAGAGAFALAFEDLLVWIGEMESRLARYQVLSVYVEKLQEQFDELNELSEEVSDHQKQVDELSVSGQELMRHASGNDAIQLKDRLDSLQLRYSDLAQRASERLRQAREALPVAQSFHSAHERLIRWMDDAETQLRAL--EAAALTAQ--ESTMQRLEQELQEM-RGVLEVVNHLGPQLCQRSPGEGAGVVESMVSRANRRFDAICEQIQRRAERLELSRQRSLEVTGDLEDLLDWFHEVERQLAD-AQPIVAEPDTLATMLREQKALSEEVSSQKGRVRDVLSAAKKVAREWPAEDQAAVRDRAEELRALSIRVAEACAERLAALEQALPLAEHLLEAHSELVAWLDEAESEAERLAAPAAPHPAHIQRQQERNRALLQALAEHKPLLDRLNKAGTALAKLCRPPDAHKVQRLLSSDNERYNALRKLLRDQQNLLEEAMQSTSQFADKLDGMLSALASTADQLNNAEPISAHPERIQEQISDNQAVVSDLGKKSPALEAVQKAAREVIA--KAGGDQEPSVR-------------DIRQKLERLNGLWEAVQQAARTRGHSLESALAVAERFWEELNAVMRALRDLQENLDSQEPPAVEPQAIHQQQEVLHEIKQEMDQTRPEVDQCRQAGQDLMQLCGEPDRP--------EVKRHIEDLDSAWENVTTLYAKREQNLIDALDKAMGFHDTLQSLLEFLDTAEQKYANLGPVAADIDAVKAQIGQLRDFKREVDPHMVEVESLNRQAKELSEQTSSEQARALRQPLDEINRRWTALLRGLVERQRELENALLRLGQFQHALGELLVWMARTERALDECRPVAGDAQVIEVELAKHKVLMNDIQAHQSSVDTLNRAGHQLIEADRHSEDASVTQTKLADLNRRWKALQDKAAQRQQQLEAALREAQAFNQEIQDLLMWLSDIDGQLASSKPVGGLPETAREQLNRFMELYNELDSNRHRVESVLQQGQEYTRAAEGSTG--LQHSLRTLKQRWDNVLTRANDRKIKLEIALKEATEFHESLQEFVEWLTHAEKSLAGLRPVSRILENVLSQIEEHKSFQKDVGAHRETMLQLDKKGTHLKYFSQKQDVILIKNLLISVQHRWERVVSKAAERTRALDHGYKEAKEFHDAWMELDRWLTEADQSLDEQPPAGNDPEKIRRLLARHREFQRALGAKQPAYDACLRQGRLLRERCPKPDQPVLQRMSDELKAKWNALCNKSVDRQRKLEEALLFSGQFKDAVQALIDWLDRALTSLQAD--QLLHGDLDTVNNLVEQHRSFQTELKSRSANLESVQRTASELLKTASADDAASIRTQMSALESKWESVSKLSDSKQRKLEEALRQAEQLHKAVHMLLEWLSDAEMKLR--FAGPLPEDEATTRQQMEEHQQFMREMEQQEHNKESTIALAQEILSRCHPDAVTVIRHWVTIIQSRWEEVSLWARQREQKLAEHLRSLRDVLELLEELLRWLLAAEASLMTLEAQPLPNEVPATERLLEDHRRFMDDMSQRQADVDRISKAFASKRQPPAGSAAAGTKDRPSQQRHDRRTPHAASQSTPRTSTPTRGHAAAEPEIRHPRARELLDKWQHVWLLAMERQRRLLEHLKYLQELESIKNFDFDEWRRRFLGWMNNKKSRVMDLFRKIDKDNDGKVTKEDFIDGILKSKFPTSRLEMERVADIFDRNGDGYIDHKEYIDPLRPDRDCLVHGAKQNKPLTEAEKIQDEVQRQVAKCTCVHRFKVFQVGEGKYRFGESQKLRLVRILRSTVMVRVGGGWVALDEFLVKNDPCR----------------------AKGRTNLELREQFILAEGVSQSMTPFKPKAFSRAGPITK 4782 HSP 2 Score: 467.233 bits (1201), Expect = 3.588e-127 Identity = 344/1280 (26.88%), Postives = 645/1280 (50.39%), Query Frame = 3 Query: 354 INLLQLDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEED----IEEKIYQFRNQYADLYANLNSALEELNDDFDHNDF--------RIDFNQTRLENNYLTYLKQYESFCHLF--DDISKVDRNNENQRKFHTISTL--------WSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDGY-PADQHYRIIININGKIDKVKKKFEK--LSPPTLSSGVISNRQYTP----IHSMELGDNVLY-SSLNKWKNWIDEKCAIISEINFTNDLDGLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMD----FHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANIDENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQE----LSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKDVPTNLDQLISAV--TTSRQNQKDVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFESKNIESLMKKINNFQLEINKYKPEIDEI 4073 +++LQLDP DR VLR+ADERDA+QK+TF W+N HL+K NKRV D+F DL+DG LL+LLEVLS + L + RFH L+N+ T L+FLR + +KLVNI AED+VDGNPKLTLGL+W IIL FQ DI + ++ L+ K+ LL+W+++ + YP + + +F++SW+DG AF A+IH+ RPDL+D +S + ++NL++AF+ A++ELGV ++++PEDV + DEKS++TY++SL+++ P+ E++ + +Y +L ++L+S L + F ++ R + +Q + H D++ + R +++ H + L W + T ++ L +E+ +++R ++++ + + + N+++++E +I + + + + + ++L E+ + + VQ L Y A + ++++ ++ + ++ +++ L+P T + R+ T I L + Y L +W+ EK + ++ ++ + E+ I M + + ++ + + + L+ ++EL + +K +D + LEF + + W+ ++ ++ W + ++ L E ++ L E+E RE++ N T+ G++L H AA I+ L+ L+++W W+L L L+ HL A Y QFF EA E + + +LN+ F RP L+EGE L ++++++ E + Y VN ++ S+ V L R + + + V A+CS + GE L +N+ D W+V NS+ P +CF+I +P+A + A +L + + LWTK++ +LR ++ +T+ +VK W + F +EP R+ I+ LN+DA +L+ + + + ++ + + CN F +L + ++ SP + + DL + K LQE L+ ++ +P+ DVD L+ V +HKEFE L++ EPQV ++ + K +T + + + ++ LW+++WN +H++V +LK+ E+ L E + +E L Q S P + ++ Q + + + L + +++V T R S+ D++KL+ +L+ V R++ NQ+ +RL S +N++ + W V + +V + + + ++ EI + I+EI Sbjct: 2 LSILQLDPADRAVLRIADERDAIQKKTFTKWVNKHLIKANKRVDDLFVDLQDGHGLLSLLEVLSGETLPREKGRMRFHMLQNVQTALNFLRYRKVKLVNIRAEDIVDGNPKLTLGLIWTIILHFQISDITFTQNNESLTAKEALLRWAQRTTDRYPGVKVRDFTSSWRDGLAFNAIIHRNRPDLVDFRSCRTRTVRENLDVAFSVAERELGVTRLLDPEDVDTPQPDEKSLITYISSLYDVFPEPASHHPFAEDEKLRKAEEYRELSSSLHSWLRQSTTTLQSRSFPPTLSEVKQLQTENVRFRQEEVPPRQQDKQRLHKLWRDEVHSLVR----EQRLHVDADLTPDNLEASWQRMLTAHADRDRALRDEAARLERLQRLAEKVHRDAKSCDNRLDDVERRIAEEEPRLGRLHPADAKRVCDQVERDLRHIEDALKALFRDVQLLFDGRYHRASELHKLVQKLHERWSNLRLAYQQRLLAPLTSKQYKLEERKVTKQRQVISESRLVETHEYLKFLQSCLDWVQEKLRQLEAADWGCEVPAVQVALERHQADHRLIDQFQKNVDMCISRQGHFEEGSEERAQYQKQLAQLERAYSELLVLSNKRLSDLDALLEFAQSAATELRWLSERQQPEVMRDW-SSPTLNLVELEQHQGTLTAEVEARESAFNATLDQGSSLVRQQHPAARAIEAQLSALQAQWAWLLELLRALEAHLRHAAHYHQFFKEARECEQWLQRGEERLNTTFSRP-SFSLEEGERLLQQMQELREDLARYAGIVNALLERSRQVLPLKQRRAPL--PRPLRVTAVCSYSQ----LNMTVARGEQCWLHDNTQRDRWKVANSKGHEGQVPGVCFMIPPPNPEAIELAESLKRKYDLVVKLWTKKQHKLRLNMIFATIKIVKAWDLKTFRAMEPSQRESIIRALNEDAEKLLAE---GDPTDPDMRRLREEIRLCNKLFEDL----LAKLREEEAEKSPESPSR------------RFADLSARLEKQLQEKERTLNARVQAPIPRDVDSLDALVVQHKEFEEGLQDLEPQVAEMRVAFKQMTKKTPTTQDRHDGVVRLWDRIWNLSHLYVERLKAVEIANHGLSEATTFVSSVEEQLAAQG-SMPEEQNALR----QTHEDLVALQLELQQQQPQLDRLAEDVASVRKVTERSRPSAYSHPDVRKLEDDLRKVVRRWDNAANQLAERLRSCEAASELLRAYRNKMDEERHWASQATVRVNAVKTARPSVDRQQALAAAQERCKTCDDEITELSSWIEEI 1245
BLAST of Dystonin vs. TrEMBL
Match: A0A4D5RZX0 (Putative microtubule-actin cross-linking factor 1-like isoform x6 (Fragment) OS=Ixodes scapularis OX=6945 PE=4 SV=1) HSP 1 Score: 963.755 bits (2490), Expect = 0.000e+0 Identity = 669/2325 (28.77%), Postives = 1225/2325 (52.69%), Query Frame = 3 Query: 12384 IAQISP-VNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQK-IETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANND-----PELAKL--LNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYG---FESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVR--ENDSLTGQVGERNMEILENETNSVEKLVCQARNDLD-KLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ-RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALM-IQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQ--QFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEI-----------------------ITNSKKKTPPLIPIFDRSKRMETNQGISKI------------QEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRE-----TYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPAT 19181 +A SP + T + E++ + R+Q L+S L + L S + + ++++ +L E+++N D+ ++ QI ++ N + + + E + + + E ++L + A+ + ++D L ++ E R +L + +F D R + EA N+ P A + + + + F + V+PL K+++E+ +GN + G+ +E+++D + ++ L + +S+ E +D+ L++ KF +L +++++++ + ++ PS +Y K+QL + L L RQSS+ L G++++ N +K+ +Q++L +L+ ++E L A+ + +R + ++K+F++ P + WL+ E+ LA T PT D + R+Q+++ L D S ++L I + G+ ++ + + ++ DR++ + +LL + ++ VN FED L ES + ++ V + ++ +EE L E+ H++ + +L G+DL + +S +D+ + +++ LH + +++ A ++L + ++P+A F ++ ++ + + A ++ E+ +LT Q E ++ LE E V + V + N L +L + E ++ VE + +RF V ++ ++A +I ++ ++ ++D ++ + E+++ ++ I + L + L + QK + + +KKL R++P D ++ + +K S T A + L++A+PLA+ F+ ++ L WL E E + +L Q+ + + AL + ++KPLLD + K+G L ++ + +GK + I +RYN ++ ++ + LE+ + ++ +K+D N L + D++ ++ S HPEK+ E++ ++ DL K ++ ++ K D++ +V + KL +++ +G+Q + + L+ A FW +L + ++ +L + + ++++ +++++ ++R E++ + ++ + Q G+ L++ P++ P+V++ E+L +E V S ++ N+ + + L E+ + LGP+ ++ V +QI + ++ K +++P ++E +N+ +L + + N + + IN W LL GL RQ +L+ LL LG+F A++E + WI TE +L + + GD +E+ LA+HK++ D+ Q SV + R ++I+ D S ATQ +L L + W+ L++ A + +LE ALKEA F + Q++ + ++ +L K GGLP+TA+EQL RFM++Y ++E +++ E +K + + A++ + L ++WD V N A RK +LE A++ FH + +F+ WLT +EK L +PVSRI+ +L Q+E H+ ++D+ +HRE MLNLDK THLKY SQK D++LI+NL+ S+ HRWE+VVS+++ER+R+LD+GYKEAK F D L +A L+ + G P KIR + +HKEF LG YD+ R G L+++ P D + ++ +L+ +W ++CNKS++R++ L +ALL SG +KDA+ L+ WL L + + GD++TV L+ +H + +L+ R +E + A L+ S ED+S I Q++ L+S W+ V+KL K+ RL+EA QA + + + L E+ S +E +LR F P E E I+ H F + M+E ++N + EIL +P+A I+H++ II+S+W ++ W+ QR L+DHL L + LL++L+ WL AE TL A E++ L + + ++H+ F+ DM+ +Q D D + ++++ PL R T G S+ EP +P+ +L KW+ VW + L R++RLL+ ++YL+E+E++KNF+F++WRRR++ WMN+ KSRVMD FR+ D D+DG+VT+++FIDGI+ SKF T+R+EME VADIFD+ G+ID+++++ LRPDR+ Q KP E E I DEV++Q++KCTC + +K+ Q G+GKY+FG+++KLRLVRILRS VMVR+GGGW ALDEFLVK+DPCR AKGRTN ELRE+ G +M PFK K A+ Sbjct: 3799 VASASPDSDTTHIRKEVDDLTRRHQQLTSKLEDRCAQLESASSVVAQYNNKVKTAHQDLTSLEEELENMGAIGRDIRTVNGQIDEVKNFKVKLSTTEDEIQDAERECKDLINHGYTQDAKGARTQLDTLKRQLNRLQERTKGRSLALDQMLAKLEKFYQDLGDIQRSLSEATNEERAFRPVAADVDTIRSQQEEFKHFRKSCVEPLGKEIDEISRVGNGLIQSASPGVNTAILERDVDKLNDEWNLLKEKMSERERKLDVALLQSGKFQEALAGVEKWLQDTEEMVANQKPPSSDYKVVKAQLQEQKFLNKLLLDRQSSMTSLMTMGNEVMRNLAPSEKAHIQSQLQDLSQRFERLNRGAQERMSALERTLPVAKAFQEKMCPLVEWLEQTERRLATMGTIPT-DQDRIAHRVQDHRDLHRDILGHKHSFEELTEIAQTLMGLVGDDEAQAVVESMQEVTDRYARLVEDSERLQQLLAEARAGANAFV--VN-FEDLLVWIGEMESRLSRYQVLSVYVEKLQEQFEELSELSDEIADHQKQVDDLTGSGQDLMRHASGDDAIQLKERLDALHVRYTDLTQRASERLRQAQEALPVARNFHSSHERVVVWIDDAEAALKSVESSALTSQ--ECTIQRLEQEIQEV-RSVLEVVNHLGPQLCQMSPGEGAV-VVESMVSRVNRRFDAVCEQIQRRAERIELSKQRSVEVVGDIDDLLDWFRDVERQLAN-AEPIIPEPEALAAMLKEQKALNEEVSSQKGRVRDILASAKKLARESPPEDQALIRDKAEDLKALVASVTAACADRLSALEQALPLAEHFLETHLDLVQWLDEAESEAERLGAPSLHAGQIKRQQDRNNALLQAVTERKPLLDKLTKTGAALIKLCSPSEGKKVQYLINSDSERYNALRNLLREQQNLLEEAMQSTSQFADKLDGMLNALASTADQLNNAEPISAHPEKIQEQISDNQAVVTDLGKKSPALEAVKKAAREVI--AKAGGDQEPTVR-------------DLKRKLERLNDLWEGIQKAARTRGQSLETALAAAERFWEELNAVMRALRDLQENLDSQEPPAVEPQAIHQQQEVLHEIRQEMEQTKPEVEQCRQAGQDLMQLCGEPDK-PEVKRHIEDLDSAWENVTSLYAKREQNLIDAMDKAMEFHDTLQNLLEFLDTAEEKYSTLGPVASDIDAVKSQIGQLRDFKREVDPHMVEVESLNRQAKELVEHTSANQARAIREPMDDINRRWTALLKGLVDRQRELENALLRLGQFQHALNELLVWISKTEKTLEDCRPVAGDAQVIEVELAKHKVLMNDIQAHQTSVDTLNRAGHQLIEADRHSEDASATQTKLNNLNRRWQALQDKAAERQRQLEAALKEAQAFNQEIQDLLMWLGDVDGQLASSKPVGGLPETAREQLNRFMELYNELDSNRHRVESALQQGQEYTKVAEGTTTTALQHSLRTLKQRWDNVLNRANDRKIKLEIALKEATEFHESLQEFVEWLTNSEKYLTNLKPVSRILENVLVQIEEHKTFQKDVGAHRETMLNLDKKGTHLKYFSQKQDVILIKNLLISVQHRWERVVSKAAERTRSLDHGYKEAKEFHDSWAELDRWLAEAERSLDDQPAAGNDPDKIRRLLARHKEFQRALGAKQPAYDACVRQGRLLKERCPKADLPVLQRMLDDLKARWNAVCNKSVDRQRKLEEALLFSGQFKDAVQALIDWLDKALGTLKE-DQLVHGDLDTVNNLVEQHKSFQTELKSRSTNLESVRRTASELLKTASSEDASNIRQQMSILESKWDTVSKLCESKQTRLDEALKQAEQLHKAVHMLLEWLSDAEMKLR-FA-GPLPEDEATTRQQIAEHQQFLRE--MDEQQVNKDKTIALAQEILAKCHPDAVTVIRHWVTIIQSRWEEVSLWARQRQQKLEDHLRSLRDILDLLEELMRWLLGAEATLTALEAQPLPDDIPLVERLIDDHKVFMEDMSKRQPDVDRVSKAFSGKRQQPPVQQPVQQLQQHPVGARRRGEPL-----HHDRRTTPHGASQSTPRTSTPVRGHHAEPEIRHPRAKELVDKWQHVWLLALERQRRLLERLKYLQELESIKNFDFDEWRRRFLGWMNNKKSRVMDLFRKIDKDNDGKVTKEDFIDGILKSKFPTSRLEMEKVADIFDRNGDGYIDHKEYIDTLRPDRDCLVHGARQNKPLTEAEKIQDEVQRQVAKCTCVHRFKVFQVGEGKYRFGESQKLRLVRILRSTVMVRVGGGWVALDEFLVKNDPCR----------------------AKGRTNLELREQFILADGVSQSMTPFKSKVAS 6066 HSP 2 Score: 74.7146 bits (182), Expect = 1.315e-8 Identity = 224/1140 (19.65%), Postives = 455/1140 (39.91%), Query Frame = 3 Query: 14781 KEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDA-KKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVH---PEKLDEELGVF-----------------------------DEILYDLDKLQIFVDKLQIGIENCSP-----SRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQL------IEKVNNPNETP--DVEQAEEELK-------------------RNFEAVRSSCEQQITNIDRQ-QSLI----------------------------TK-----LEEMRMKLDEWFK----------EVNNRLFILGPLPTETRPVLTQIQKTKEL-KNDIEPKHRDIELINQLGYQLTKGSHPNIKNQV-NSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLP---DTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTL---LDDIASNLEILERDTSIGQ--TPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQS-EEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHE 17840 + F S+ ++ WL E + + + + D D LH+ E + S D++ + +++ G + + R Q L DA +K ++ I++ R T L+ + N ++ L+ R D S H EK +EL F + + DLD L+ +KL G+ + S S K A +D + E++ S+ + +K+A S G ++ + E++ LL A E L D+ L S D +T + +K ++DL H++ K+ + QL + + NN +T D+ EEEL+ +NF+ S+ E +I + +R+ + LI TK L++M KL+++++ E N P+ + + +Q ++ K K+ +EP ++I+ I+++G L + + P + + + ++ND W L + + +R+ +L LL G+F A+ +W+ TE + N K D ++ L + K + + Q+S++ + E+++ S +L+ L + +E L A+ + LE L A F Q+++ ++ L G +P D +++ D++R E+ E + + +A+ M+ + ++ + +E + L +A F ++ + W+ E L++ + +S V + EQ E L +I H++++ +L L + D + ++ + ++H R+ + R+SER R A+ F + + +DD + L+ +E Q T ++ ++I +E L V N LG QL +P + + ++ +V + ++ ++C + R + + + S + +LL W R +E +L+++ + + +L E L +++ + + I A L +S ED + I D+ +LK+ +V ++ LE+A A F L ++ ++E E Sbjct: 3517 RGFFSTCEDIQGWLQEIQHTLSPDFKISADTDILHRQVTEFEPAYKSLLDKEHEVHLLLSKGTDMVAKMTRKQESQQLRTRLDAMRKAWDKIRKEATDRHTRLQRAFENCKKFNAAFNKFGPWLQTTEARFYDLGPISYHRPETEKQAKELQGFKNEISRHSQEYDSVRNLGETFLSGCDVDKEGVKKDLDTLRTRWEKLNQGVTDRSRELDEVSAKLAEFQDKARELNHSL-------QRMEDKVA--SHDALGDAARNPQLLERMKALLREAEELQRGL----DRLRAFAEGLVASASPDSDTTHI---RKEVDDL---TRRHQQLTSKLEDRCAQLESASSVVAQYNNKVKTAHQDLTSLEEELENMGAIGRDIRTVNGQIDEVKNFKVKLSTTEDEIQDAERECKDLINHGYTQDAKGARTQLDTLKRQLNRLQERTKGRSLALDQMLAKLEKFYQDLGDIQRSLSEATNEERAFRPVAADVDTIRSQQEEFKHFRKSCVEPLGKEIDEISRVGNGLIQSASPGVNTAILERDVDKLNDEWNLLKEKMSERERKLDVALLQSGKFQEALAGVEKWLQDTEEMVANQKPPSSDYKVVKAQLQEQKFLNKLLLDRQSSMTSLMTMGNEVMRNLAPSEKAHIQSQLQDLSQRFERLNRGAQERMSALERTLPVAKAF---QEKMCPLVEWLEQTERRLATMGTIPTDQDRIAHRVQDHRDLHRDILGHKHSFEELTEIAQTLMGLVGDDEAQAVVESMQEVTDRYARLVEDSERLQQLLAEARAGANAFVVNFEDLLVWIGEMESRLSRYQVLSVYVEKLQEQFEELSELSDEIADHQKQVDDLTGSGQDLMRHASGDDAIQLKERLDALHVRYTDLTQRASERLRQAQEALPVARNFHSSHERVVVWIDDAEAALKSVESSALTSQECTIQRLEQEI---QEVRSVLEVVN-------HLGPQLCQMSPGEGAVVVESMVSRVNRRFDAVCEQIQRRAERIELSKQRSVEVVGDIDDLLDWFRDVERQLANAEPII-PEPEALAAMLKEQKALNEEVSSQKGRVRDILASAKKLARESPPEDQALIRDKAEDLKALVASVTAACADRLSALEQALPLAEHFLETHLDLVQWLDEAESE 4623 HSP 3 Score: 72.0182 bits (175), Expect = 9.078e-8 Identity = 88/441 (19.95%), Postives = 189/441 (42.86%), Query Frame = 3 Query: 10740 QDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEE-------IQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTG--KSIENKHQQINDLKNL 12035 Q+LLR + PG L+ +L L ++ L + + L L + + K F + + N + +K++M VLGP+ AQ QQV + DE E ++ + GQE++ + P + +I + ++ + + + + L++RE ++ + G + DF+ ++ + + L + + D+ + + D EE + L++ + L ESE + L + ++D + EIK K + + KI++ + + + ED + WLQ Q L+ ++ L + + + + K+ +V + ++ M + + +S+Q+ +L + + I + + Q+A + K N NK W+ + + P+ ++E + E G I Q+ + ++NL Sbjct: 3256 QELLRRKPNAPGSESLQQQLTELLSRWQELLQAIRIRLLLIQ----EFKDFQDTHDLLHNWLSQKDKMFQVLGPIAHEPRMVAAQTQQVLVMRDEFSSQEPLLRRMNLCGQEVVGQLEPNNPAGRKIRDQMEAIKRHWNEMIGRLEERERSLGAATGATTDFHTVLGKLLEALQNIGDDFDQ----LAEAGDLEEQLRRLRGLDDRLEAQRPPLAESEAMCDHLCDILTDVASRNEIKGKWGTADKLYNNLNRKINNRKAELESSLREDRGFFSTCEDIQGWLQEIQHTLS-PDFKISADTDILHRQVTEFEPAYKSLLDKEHEVHLLLSKGTDMVAKMTRKQESQQLRTRLDAMRKAWDKIRKEATDRHTRLQRAFENCKKFNAAFNKFGPWLQTTEARFYDLGPISYHRPETEKQAKELQGFKNEISRHSQEYDSVRNL 3687 HSP 4 Score: 68.9366 bits (167), Expect = 7.284e-7 Identity = 150/741 (20.24%), Postives = 298/741 (40.22%), Query Frame = 3 Query: 15726 QAEEELKRNFEAVRS-SCEQQITNI-DRQQSLITKLEEMRMKL----------------DEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPN--IKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEI--IKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEM-FKFSGGLPDTAKEQLKRFMDIYRTF-PKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMA-THLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTL----------------LDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQS-EEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFF 17822 Q +E L+R A S S +QQ+T + R Q L L+ +R++L W + + +LGP+ E R V Q Q+ ++++ + + +N G ++ PN ++ + I W ++ L +R+ L + +FH + + +E + + + E GD LE L + + + + + +++ E + I DV+S +E + K + L + ELE +L+E F+ ++I + E+ L FK S D Q+ F Y++ K + + + ++K + + + + ++ + K WD ++ A R +RL++A E + F+ KF WL TE P+S +Q + + K +I+ H +E ++ + T L D ++ + ++ RWEK+ ++RSR LD + F+D R L L D A N ++LER ++ + +++ + + + F L + +P D+ I + V +L + Q L +K +R L A + Y + + L ++E +L + G D+ TV ++E + +L + I+ + L+ +D+ QL LK N + E K +++ +++ L++F+ Sbjct: 3254 QVQELLRRKPNAPGSESLQQQLTELLSRWQEL---LQAIRIRLLLIQEFKDFQDTHDLLHNWLSQKDKMFQVLGPIAHEPRMVAAQTQQVLVMRDEFSSQEPLLRRMNLCGQEVVGQLEPNNPAGRKIRDQMEAIKRHWNEMIGRLEERERSLGAATGATTDFHTVLGKLLEALQNIGDDFDQL-AEAGD---LEEQLRRLRGLDDRLEAQRPPLAESEAMCDHLCDILTDVASR-NEIKGKWGTADKLYNNLNRKINNRKAELESSLREDRGFFSTCEDIQGWLQEIQHTLSPDFKISADT-DILHRQVTEFEPAYKSLLDKEHEVHLLLSKGTDMVAKMTRKQESQQLRTRLDAMRKAWDKIRKEATDRHTRLQRAFENCKKFNAAFNKFGPWLQTTEARFYDLGPISYHRPETEKQAKELQGFKNEISRHSQEYDSVRNLGETFLSGCDV--DKEGVKKDLDTLRTRWEKLNQGVTDRSRELDEVSAKLAEFQDKARELNHSLQRMEDKVASHDALGDAARNPQLLERMKALLREAEELQRGLDRLRAFAEGL----------------VASASPDSDTTHIRKEVDDLTRRHQQLTSKLEDRCAQLESASSVVAQYNNKVKTAHQDLTSLEEELENMGA-IGRDIRTVNGQIDEVKNFKVKLSTTEDEIQDAERECKDLINHGYTQDAKGARTQLDTLKRQLNRLQ----------ERTKGRSLALDQMLAKLEKFY 3956
BLAST of Dystonin vs. TrEMBL
Match: A0A1S3K4B8 (LOW QUALITY PROTEIN: microtubule-actin cross-linking factor 1, isoforms 1/2/3/5-like OS=Lingula unguis OX=7574 GN=LOC106178456 PE=4 SV=1) HSP 1 Score: 963.755 bits (2490), Expect = 0.000e+0 Identity = 687/2357 (29.15%), Postives = 1227/2357 (52.06%), Query Frame = 3 Query: 12240 AEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKS--MHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIR----------KIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKH---MEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDR-LKKRQSSLDELNKAGSDLLINTKEP--KKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQN---DDSSIDESIKKL--KIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKL---VCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQ--KINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPI------FDRS--KRMETNQGI------------SKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKP-ANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF 19163 AEE L+ E + + V + +++T Q+++ + E+ ++ Q V+ ++ +++ + R+ L+ ++ +L+ L + + E I+ +T +K+ + + +H + +L+ E + ++ + + ++L A+ S ++D ++ EK+ + +D S+ ++VT + + N R K+D DP + + + + AFS Q + ++ + C V+S H M +++ +K R+ V+ + + + K F SL L ++ + + +++ K L + + L+ Q L+ ++K G L +++ P S L+ +++ L K+ L + D A+ S F + L WL E+ L P+ D + ++QE K LQ D E+IKK+ K+ DG + VS ++N + R+ E + E+ + L + + + +++ D L E M + + + R + +EV H E L + GE+L Q+ + + A + K++ L + ++ + +L + +P+AE F A+ K +L L +R D ++G+ GE +E ++ + N++ + V Q + L KL A ++ED+ ++ KRF+ + +V KKA KI ++ ++ +E L +++ FEQ ++ + + I++D L+E D L N+ K + +KL+R+ D +++ +D +K+ +++ ++ + L++A+PL+ F ++ L+ W EE + + + L+ DQ+ K + ++ L +QKPL+D + K+G + ++ + + I ++ R+ IK + R+ +LE+++ +E +EK+D L +++ + S HP+KL ++L I+ DLD+ + ++ + S A D++D +++ ++ +++L ++ S ++ T E + L +++ FW +L + EM + + L + ++++++E L+ +I+ D+ + Q GK+LIE P+ P+VE+ EE+ +++ V++ + ++ S TK +E + L +W + LGP+ +T V QI K K ++PKH +E +N LG +L K S + V +A +N W L+DG+G+R+ +LQ LL+LG FH A++E + W+ TE +L I+ GD +E+ +++HK+++ D+ ++SV + ++I + S+ +L+ L W+ + R K +LE A +EA +F+G+ + + + ++ + L K GGLP++AK+QL RF++I++ +++ + E +I +K ++ + +++ L +WD V+ A+ R+ +LE A+ + F D+ FI WLT TE+N+N +PVSR++ TI++Q+E H+ L++DI+S+RE+M LDK THLKY SQK D++LI+NL+ S+ HRWEKVVSRS+ER+R LD+G+K+A++F ++ + L D + + +L+ + +I P KI+EQI KHKEF LG YD+ +R+G L++K+ D + ++H ++ KW S+C KS+ER++ L +ALL SG+ +DA++ LL WL +EP L++ + GDM+TV LL EH +++L R + + L+ SEED+ +++ L ELK+ W+ V KL+ +K++RL+EA +A +F + L E+ + +E LR + ++E+E +S + + L+ E + G +IL ++P A +KH+I I++++W ++ +W+ QR L D L L+ LLD L+ WL AE L E L + E + EHE F DMT +Q D+D +T ++K+ P L F+R KR T + + + EP F NP++ L +KW+ VW M ++RR++L D +Y KE+E +K+FNFE WR+RYM WMNH+KSR+MDFFR+QD D DG+VTR+EFIDGI+ SKF T+R+EME VA+IFD +K GFIDYR+F+AALRPD + KP +NE I DEVK+Q++KC C + I + G+GKY+FGD++KLRLVRILRS VMVR+GGGW ALDEFLVK+DPCR AKGRTN ELRE+ +G +MA F Sbjct: 7671 AEEKLEMMEPVALERMKVIQQHKDVQTLQTEIVRKTHNHESLNTQGQTLMQNVDVDKQVVADQLDAVNQRWDSLNKAVDDRLLTLEDMSQKLHEFFDLIKDLSTSLSKYEDKLSSHDALGA-VAKGSRYLHIIQSLQEEVHSMQPQIDYTQELAQSLISAGPANAKTSQITSRVDEVSERYEKLAQEVDSWLASIETGSQVVTGAQQQVNTVGRQLQGFEEDLEKMDACGRDPHV---VEQQLQELQAFSAQISEGAAA-----VNEAEERCHNVMSQGYIGHGDPMLAQVEDLKKQHSRISDRVAQRQGELSGMMNKLDDFHDSLRQLHTAIDRAAEEQESQNPVGGNADNLKKLLQELKTFEKKSLEPIQKQLEVVSKQGQQL-VSSAAPGVSTSGLECDIESLMDKWNELNQKVRDREAALDDALLQSGKFSEAVSALLDWLGETEE-LMEHQKEPSADYKVAKAQMQEQKFLQKMLEDRQGNVEAIKKIGSKLSTEDSDG---QQVSA----QVNDIVKRYEELKAGATERRQSLDTMMTVAKEFQEKLEPVIDWLDTTEKKMASAEPVATESEKIRQQLHHQKEVNEEVADHGEDLAAALKKGEELLQLCNGEERAHVQEKLDELKLRYSALNEKSADRLQQMDEVLPLAEEFEDAHGKFLDLLNRLEPELRGKD-MSGKEGENQLEEIQAQMNNLVPILTAVSQTGHPLSKLAIGSA---GAAEIEDLINKDTKRFEALKEQVDKKAEKINFSKQRS---QELLKDISDLMDWFEQTGRLIQTAQPISSDPGVLKEQLQDHKALTEEMNQNKGKAREVVTIGRKLLRETSIEDDGTIQDKMDDLKQLTDNVSRLCTDRLGLLEQAMPLSVHFHDTHRDLEAWFEAVEEKITEQDVPALNTDQIKKQQDGVRILRQEIIEQKPLVDKLNKTGQAMIKLCGLEEARKIQEFMDTDNNRFEMIKNSTRERSNNLEEVMQQTSEFSEKLDNMLETLVATAEQVEHAEPVSAHPDKLRDQLEENKAIIEDLDRRLAALHSVKA---SASELISQAVDEEDE---------SVKDMKDKVDELVQLYSD---IRKATEERTAVLEETLEVSDTFWVELNQLMGTLKEMQDTVELQEVPALQPELIREQQEVLEALKEDIEASHTDVDDVHQVGKRLIELCGEPDR-PEVEKNIEEVDTHWQDVQAQMVTRAKLLEDAMSKATKFQESLIHLLDWLQVTEEAFIGLGPIGADTDTVKMQIDALKAFKGAVDPKHVSVEALNHLGQELIKDSTTDQGAVVKDQVAEVNKRWDALIDGIGERRAKLQQALLNLGAFHVAMNELLSWLDKTEQTLDEIQPALGDTRLMEIAMSKHKIVQNDVEAHRSSVDSVNDAGKQVISSEGSADASSTRHKLDLLNMRWDAVLGKTRDKQLDLEHAYREAQVFHGELADTLQRLSDIDAHLITSKPVGGLPESAKDQLNRFLEIFKDLEGNEPRVQDLLSEGEKIVQKCGETTATNLNQNLQALKNRWDNVRARAKDRRKKLEDALAQADKFQADLNSFIAWLTNTERNINNLKPVSRVLQTIVDQIEEHKGLQKDISSNREKMAALDKTGTHLKYFSQKQDVILIKNLLLSVQHRWEKVVSRSAERTRQLDHGFKQARQFHEVWQELNDWLNQSEAMLDTEQTISNDPVKIKEQINKHKEFQRTLGAKQPIYDTVQRMGRVLKEKSSEADEPVLQNLLHEVKNKWNSVCGKSVERQRRLEEALLFSGHLRDALSALLDWLYKVEPTLTE-EQMVHGDMDTVIALLEEHKAFQQELGKRSSSVGSVQKSGKDLIENSEEDAGDLQNDLIELKTRWDRVCKLSVDKQKRLDEAMKKAEDFHKRAQQLLEWMADAEMHLRYHSHIADDEEE--LSQQLEDMKSLQAELVKQEENLKTTLALGGDILKQSHPVAVMPVKHWITILQARWEEISTWANQRERRLTDALSELHNSMALLDKLMTWLQTAESHLTYQEQEPLPVDMEEIEKLTKEHEEFENDMTSRQPDYD-CLTKTQKRRPSLDSSSGLLSPFERGSPKRSSTPRQMKYDARGRAGSTPTPTAEPQFKNPRVTALFNKWRHVWLMAMDRRRKLQDAQDYFKEMERLKDFNFETWRKRYMKWMNHNKSRIMDFFRKQDKDRDGKVTRQEFIDGILISKFPTSRLEMEAVANIFDHDKDGFIDYREFVAALRPDNKA--AKPEQTDNERILDEVKRQVNKCRCQKKFHIHKIGEGKYRFGDSQKLRLVRILRSTVMVRVGGGWIALDEFLVKNDPCR----------------------AKGRTNVELREQFILAQGVSQSMAGF 9958 HSP 2 Score: 486.493 bits (1251), Expect = 6.960e-133 Identity = 361/1302 (27.73%), Postives = 658/1302 (50.54%), Query Frame = 3 Query: 393 LRVADERDAMQKRTFENWINCHL------MKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPK----EEDIEEKIYQFR-NQYADLYANLNSALEE-----LNDDF-----DHNDFRIDFNQTRLENNYLTYLKQYESFCHLFDDISKVDRNN-----ENQRKFHTISTLWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDGYP-ADQHYRIIININGKIDKVKKKFE-----KLSPPTLSSGVISNRQYTPIH--SMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLDGLNKIYEKFSTTFNEIKDSVDEFKMILES--ENKYQMDMD----FHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKF--------KNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLKCANIDENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLILFVKNGMSETVGLKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEAAQDTISSVVGNLKDVPTNL--------------DQLI--SAVT---TSRQNQKDVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFESKNIESLMKKINNFQLEINKYKPEIDEINKSATYFL 4097 LR DERDA+QK+TF W+N HL K ++V D+F DLRDG L+ LLEVLS + L + +FH L N+ LD L+++ IKLVNI A+++VDGNPKLTLGL+W IIL FQ D++ ++ +L+ K LL WSR+ E YP +N+ +FS+SW+DGKAFLA+IH+ RPDL++ ++I N+ ++NLE+AFN A+KELGV ++++PED+ DEKS++TYV+SL+ + P+ E+ +++ Q R +Y L + L + L++ L+ F + +FN+ R+E + L + + LF ++ + + + + ++ L +F +EK + + E+ +++R ++++ + + +++IE K+ + + + E + +I L E I + VQ LK Y A+Q Y+ I + + ++ E KL+ + + IS ++ T + S + N + + WI E+ ++ + ++ DL + +K +I +EFK +E K + D + Q + ++ ++ L ++ +S L+F+ ++ + W+ KED ++ W +++++ +E+ EK+ K+L+ +LE+RE N G L + H A+ I+ ++ ++++W W+L LT CL+THL+ Y QFF +A + + T+ LNS + R V +++GE L RE +DM + +++Y++ + ++A S+ + L +R ++ + VKAIC+ K+ + E L +N WRV NS + PA+CFLI + +A TA L S F L+ LW ++ +LR +++ +T+ +VK W E F L P R+ I++ LN DA ++ D E E+ + + QCN F VQ+ Q ++ +K+ +R S+ Q+D L Q LS +L + + + LE V +HK FE +L+ YE QV + V++ + ++ + +++ W LW+ AH++V +LK E+ +DE+ ++ E L A+QD+++S VG L+ +L +QL+ +A T T R + Y D+ +L+K++ + R+E + +Q+ +R+ + + +N L AW+ Q ++ Q + +V ++++ + N +++ +P+++ +N +L Sbjct: 43 LRYTDERDAVQKKTFTKWVNKHLKRHWRLSKSVRQVGDLFEDLRDGNNLITLLEVLSQETLPRERGRLKFHKLNNVQIGLDLLKNRGIKLVNIRADEIVDGNPKLTLGLIWTIILHFQISDVIVPGQAPELNAKDALLLWSRRTCEGYPGVNVRDFSSSWRDGKAFLAVIHRNRPDLVNYRAIRNNTPEKNLELAFNIAEKELGVTRLLDPEDIAVPQPDEKSVLTYVSSLYNVFPEVPSLEQSLQDNERQIRWEEYRGLASALVTWLKDNTSLMLDRTFPVTVVEMKSMLSEFNRYRIE-DVPPRLAEKQKLEQLFYELQNLSVGSSQFTIDEELHIDNVNRLLDRFTIAQQEKDMAIQAETTRLERLQRLAEKVHKDSKICDENLDDIERKMNEEQHRVEVIHPLEAKKGCDAIDHALKLTEGSIQTLFEDVQALKDGRYHLAEQLYKRIYQVQERWLALRTCLEEEIMSKLASRSFVTEGISIQKRTEVQLESRLVETNEAFKMVQDCLEWIAEQQKMLEDQDYGEDLPTVQAYLQKHRQDSQKI----EEFKQHVEKCITAKSTLPADEQKLYSQWMSKVEVAYSLLHNTYTRRTKALESLLDFIQAASVELKWLNDKEDTEVARDW-SSQTLQ-AEEIEKYYQKIYPEAKSLMTDLEIRELQFNAVQDKGEALVMERHPASKTIEAHMSAMQTQWSWLLQLTLCLETHLKHATAYYQFFEDAQHCEEWMNRQTDLLNSHYDRA-EVSVEDGEKLIRETKDMKDLLDEYQQRIEALVARSRDILPLKMRRERLISP--IPVKAICTYKQ----LNMSISKDEECMLFDNGQITKWRVANSYGREGSVPAVCFLIPPPNKEAMATAERLRSQFEHLQTLWNAKQRKLRRKMVFATIRVVKTWDLEQFQRLGPAQRETILKALNDDAEMVLSDRD--GTPEPELRQLRDEMKQCNQIF----------VQLTNQLQQEAASLKSPSR----SLLEQVDQLHRDLDHKEQVLSGRLNDTIPREREKLEQTVVEHKAFENDLQGYEDQVEMIRGSVRSPQAANPHIQTTIGVVLEKWSNLWSMAHVYVERLKCVELTLCSMDEVTGLLTGYETHL----------------------ASQDSMTSDVGILRHNKQDLMDLKQAMASKNILVNQLVENAAATRRITERSRPGMMQYPDVDRLEKDVDRLTTRWENVCDQVAQRIHNTDTAIELLSMFQNGLSKENAWLDQQQEGLQGQPPLTGDVQHARDMLDATAVLYNG---LSEKRPQVEAVNSYGGRYL 1289 HSP 3 Score: 162.155 bits (409), Expect = 6.190e-35 Identity = 239/1110 (21.53%), Postives = 492/1110 (44.32%), Query Frame = 3 Query: 8784 LQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQK-------KIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENV------LMNNASRN-----EPKLKELDDKIKQKLLVASNIEAKVNDTRKL---LGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQG----FPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPT-SITKQPTTANRQXXXXXXXXXXXXXXADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSD--------KLDSELNELLSVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVS-------DRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKI-DHSVDMIGKRSHHEDVLLTK-LEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLT---NVIENIDT-------DINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESI 11954 L++ + + E ++ D+R L + F+D+ + ++ + K+ ++ SK E + V D KD D Y+ L Q E L+ +EK K KI+ +++ + L ++ + + + +N E ++ SK ++++ + + I L + + I+ ++ ++ I L + + + S++ L WL ++ +I+N+ +SL+ + EQ I+ + A+I ++Q +E+V ++ N+ + KLK+L+ + + L S + +V D ++ L +F+ A+K+ +W T + L + ++L+ +FKEK+D + + + +E+ R + K+L+ + ++ + N+E W + L++ R K+ R+ +S YA L+ ++ L+ +E + P+A+ + ++ Q ++++ I E + I+E +G+ YD + QG P+ +Q S R PS++K SPT S K P N S SS SS D ++ +ET ++ DI RY + D L +R+++I L LS + + + + K+D + + + K+ L + + E +L + +T +L++N+ G EL L +LE++F K + ++ N MK+F + + ++ + +KE+M+ VLGP+ T + QL+QV L +E+ G ++ ++L G I+ P S E I + L+ +SKK +NL L+ RE + + S FY I D+ DRL+ + D + ++++ E IL+++ N + + + D++T ++KNK+ + ++ + + +I D+ K + E T+ D W+Q +L+ G+ TL D +RQ + LQ ++ ++ Q++ + + ++ P+ + + +KL + + +E T D N S + Q+ + + W+ + K+ PV LE + Sbjct: 6614 LKEHMDKHRAFSREVMAHEADLRFLNMAAQHFMDEAKQFQKCQLKYKK------GGDRSSKHLILPGEDIEGVRDKVKDTMDSYQDILDQCNAYSEKLDKTSEKNKHFLETVGKIEDWIKSADKRLNELDWEGVSNDAQGMYRQLEKIRTINAEAIAQSKTDRDVKHTGKELIVCLRELRASDVQIEDVEHRMNDVEDQHGFITADLMSRSSVLQTTMVQSQGVRESLDGLTDWLTNVEAKIRNLRPISLNRDTLKEQMSEIEVLQADIDAQQQAVESVNKKGAEIIKNSDSEVSKSMQAKLKDLNTRFGEAL---SRADTRVRDLEEVSDRLTAFQTALKNFDEWCIPTLDSLDSKTTLQLEPAQFKEKVDIFAQEKDSQLPYLEKLRHLGKDLIEDPRTMETGLVKDALTNVEHSWHDITALLSEREKDAEMREKHSTGYANLRTLVLLWLDGFEAKVYELQPVAVKMEVVKKQKDELKPLIEECENYGTTIDEINDVGNAYDQLQQGERNISPIRRTRQR--VSSLRSPSRLKTP------SPTRSGPKSPGYVNGSVSSESSGVSSRKSSVDNFLSLEDLTETQCQLIDINQRYEMLNDLLADRQAEIDRTL---LSLEAQKVDLENVKTWLQEHKVDP-AEHVPASQSKSQQLLKDHAKFEAEMHSKEDLIAAMKERVT---ELVKNKGDQSGTAELVKNLQQLEEEFTDAKAACEQRRRSLANMVEDMKEFKDTSRHLDKWLAQKEKMVAVLGPIATEETQIQNQLEQVKVLEEELAGHQHQYEQLVQAGSSILDQCEPESKEAQRISQQLEEISKKWNNLESSLQQRENTLKEVQTVSAGFYDAIQDIGEWAPKTMDRLSRQASISSQADIMREQERELKDLEEEAKEKTKILEDARNAYGKISDKVKDQSTKQDLKNKLEMMDKSLSDTKRRIAGRKADL--KVAMKEGEQFTQSCADLMDWVQGAMTELDSGQPVSGD-DLTLKDQLRQHEALQKEMDDRQDQLKLLLDKGQQVLTSTPPSPATADLQNKLDTIKLQWDALEKKATHRKRKLSDCNEKSSAFHQS----------LDHMTTWLQFAEEKLEMMEPVALERM 7686 HSP 4 Score: 116.701 bits (291), Expect = 2.844e-21 Identity = 208/997 (20.86%), Postives = 397/997 (39.82%), Query Frame = 3 Query: 5364 SISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIK--------LNESLISGPNQEIIH----PNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLL-KDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDE-IAINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYK--IINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIG--FKDPISGGIISPIDA-----------IEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLF--DPIRCEIRDNCGHI-------------------------------ITLNDAINEDLFPEFV------------PTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILD-------HPQSNVTVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQDSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSV-------FATIITLTNRSLYFEN-----LNKRHDNYQIISVYD-PRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHGLL 8072 + +EAL +D S I+P + +++ EA+ +T G + + F +A +KG I + ++I Q I+ P + +T A++ GI+ T+ E+++N T E + +A + FI+ ++ ++ I++ L I AI D +TG++ + ++ EG D + + QYN + + ++ F+ +I++ + D T ++ Y ++ + D E I++ A R + + G+Y + + DAI N+++ ++ V + + V + KEW+S A + I+D G + + N V+ IP +AI G+I+A+ + + + E G F+ + II IDA I + L+D + + F+N+ + + +T+ +A D GFV+T + T++ I DF + L + M++++AI +D HP G I L EAI+ L P + R+ HI I L + D+ PE PT + + G + + DPR V EA+ LD +PQ+N + ++ +V+ +++ + + F K T L D S I++V D +E +SVA R +++ HS +P T+E + +I G + +++ K L+EA+++ + D S +E+V GL++ G+S + ++ + + +V GV TA Q+ +IDP L DP +G ++ ++ G + T F N L R ++ IS + +++ EA++R +I++ + T+ + ++ + T A Q GLL Sbjct: 3754 TFAEALEAAYLDPTSAQFIEPETKRTMNIMEALDQKFLTTTGHYVYPDTGRKIHFGEAMDKGIIVESKHEGEVVKTTVIREQKQMIVDSVTDPRSGRDITFDKAVKDGILQTEMERYVNPNTGEAMPISDAVDEGFITGEIVDTQVSTEEHISSAVRRTLHITGAI-----DTRTGKMVAPTE----AVEEGILD--LPKAQYNDL--RSGRVLPFAEAIEKGLLFAEDHTVP-----KRAY-SLLSAMDPISGETINIKNALDRGILLEKTGVYVNPRSGATVPVIDAIRQNYVKAEEIETPPGVKAGTITEQTQYDIKV---VLDAANKEWLSLINAAQRNILDLQRGRFTDTLANK---VMSIP--DAISQGFIKAVLK-TQYIYTETAATGAIFRQTKTTNIIEVIDASTRERMTVIEAIRRKLLDEEMKTFYNSHTRENMTIQQAIDAGFVITTQQPRTSRTVHTKI-----DFTFDYIILEGNKEKMSVDDAIQRGYLDPATGCFIHPLTGGLITLEEAIKRKLIKTQPPLKQTREKPSHIDIQQTPEIIVTPETPKQVKPPSKPPEEEEDHIELREIARSDITPERTLQAASSRENLSSPTSPGSM----PVSGGTVSFSIKSVIDPRTGEEITVGEAVRHGYLDKQGRNYVNPQTNTRI---PIEEAVRQGLVKLYSSDPF--GKGTSPL--------AKDTKSFSIKSVLDPRTNEE--ISVAEAIRHGYLDK---------HSRCYVNP--YTDEKIPLDIAVQQG--------LIRVVHVEDSVKHTLQEALQQGLIDVARGRYTHPNTGEKMSIDEAVHRGLLI--GESREDLTALGNKSASMASLPFVGNGVTFTAAF--QL---GRIDPNTGLYHDPGSGHKMSVGEAVKQGLINPGSSTTTMTRTITKKEQRSFTNQGSATLPPRPSAFRTISQDGMATARRGLSFVEALERGLIDLHNQTFKHPRSGHLLTFEQAKQAGLL 4672 HSP 5 Score: 113.62 bits (283), Expect = 2.585e-20 Identity = 188/912 (20.61%), Postives = 373/912 (40.90%), Query Frame = 3 Query: 5595 IIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEK-LTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFL---TCPLIKFSISIDEIAINIDQTECNL---FENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHE--------KDRIYYSFTDAIDANFIQTNNEK--------SKERVXXXXXXXXXXXXX--XXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDF--------------GFVID------------IPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCE----IRDNCGHIITLN---DAINEDLFPEFVPT-----DKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNVTVYMTDVQNSVQNKTLEIPNEEKF-VDTK------TTKTLESIKRNYFGDDQDSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESV---------KMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLT------NQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFA-TIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHGLL 8072 + P +++L AI+ G++ K E++++ + L EA ++ ++L+K+L CGI++ K LT+L+AIN L TG I D + ++I + KI+T R+ + T + + ++ +T +L + + +D E ++LDEA KR ++ + H + + D I ++ N++ K+ +++ ++ +K V++P T +S +A+E G++D G YK + D G + I++A+ G I+ I ED + G +D S + S +A+E+GL+D + N ++ Q +++ EA G++ +++L + L+ F SGI+ + ++S+ + D ++ P GR + + EA + +F + + + HI T+ IN+ P+ P+ K K+T +A+ +G +D + TF DP VE A+ L + + D S + +E + + VD + T+ +++ + + D + + A + +E +E I +++ + + NA S G K ST E +T + +L +S ++P T +N+E+AI+ + + ++ S EE++ K G ++ + E + +I V+ H VG +L +T N++ Q +K P + N ++ G V + T R + L++R YQI +V DP + EA+ ++N + Y N +T ++ LS+A++ GL+ Sbjct: 1704 VFDPQSGLRMSLSQAIENGLLQLKREEYVDPSNGKHLKLSEACNQGYVDQALVKELYSLCGISDPYTGKTLTLLEAINNGLYSPITGLITDPKTGRGLTILDAIKHKILTPEAATRLSLVSITTSDMTQTQAYYGVTSMAAAETSLSLSDAIDKGAIDAHTGQFFDIVSCEKMTLDEAMKRGLLDARVMEVVHPFSGRKVTLAEGVSLGLIDTIAGKYVDNKNQRKMNLDDAHQKQLIVKPFSLHGALMKGIINYQGRVYSPRTGLVMSVGEAIEHGLLD---GQYKSLIDCQTNEVLSLSDALRRGLITSEGRFMNKKTRQTSSIHDAVNQGLIQVISEDTVFVTR-----GIRDMTSNAMYSLPEAVERGLMDPNNMRYINQRTGQTMSVLEASRRGYI-----DVRL-------AERLLTF-SGIIDVVGNQLSII--RSTQRGFFDPTMGQVRDPSLGRVMTIEEATHSGVFTFEKGQELLLLTAPVCHITTITTKIHPINQFEHPKVQPSRELAVAKKKLTLSQAVSRGLVDEQQGTFTDPATGQKTSVENAITSGRLGLISEVIQAHPMDFDVSETSHHVETGKDSRMEVDVRDSYKQETSGNMQTFRETHVKD-------RKIARARVEEEDDSDEEMEEEILTLSKSLLHDLLNAKS-GYFLEK-STREYITL-LDALQKELISRDSA--VFVDPQTKDSMNIEDAIRRGFLESTGHYTDAL--GKRMSLEEAIQKNIVIFRNKEGGVITQALKETHKFTVI---GVIDAQTGAHLPVGKAIQLGLLDQSQGLYITRNRM---GQPVKLP-------IRNAIQEGLVIIDSGATRVTRVEETQTLSERI-TYQIKAVKDPIFRTPMAISEAVKTGILNPSNGQYTNTETGQVFQLSEAIEKGLV 2564 HSP 6 Score: 96.6709 bits (239), Expect = 3.486e-15 Identity = 82/371 (22.10%), Postives = 167/371 (45.01%), Query Frame = 3 Query: 5046 KFLDPITNTELKYTDAIRYQYINDDISEILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKS----SISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEIAINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMY 6146 +F D ++ ++ +A++ ++ + E+ V P +T E V D +G D+ + L A Q+ ++ KP S L L K + + + ++ S+ EA+ G++DG + I ++ +SL +A++ GL+T G+ + K + + S DA N+G I++ + I +L A++ G++D N ++IN T + S+ EA +I L + L + GI + +L+I+++ D GQ+ D S + ++I E + + T + ++ LT P+ + +I N FE+ K+ + K+ ++L +A R +++ G + Sbjct: 1866 QFFDIVSCEKMTLDEAMKRGLLDARVMEV--VHPFSGR-KVTLAEGVSLGLIDTIAGKYVDNKNQRKMNLDDAHQKQLIVKPFS-LHGALMKGIINYQGRVYSPRTGLVMSVGEAIEHGLLDGQYKSLIDCQTNEVLSLSDALRRGLITSEGRFMNKKTRQTSSIHDAVNQGLIQVISEDTVFVTRGIRDMTSNAMYSLPEAVERGLMDPNNMRYINQRTGQTMSVLEASRRGYIDVRLAERLLTFSGIIDVVGNQLSIIRSTQRGFFDPTMGQVRDPSLGRVMTIEEATHSGVFTFEKGQELLLLTAPVCHITTITTKIH------PINQFEHPKVQPSRELAVAKKK---LTLSQAVSRGLVDEQQGTF 2223 HSP 7 Score: 92.8189 bits (229), Expect = 4.811e-14 Identity = 147/685 (21.46%), Postives = 290/685 (42.34%), Query Frame = 3 Query: 5403 NSEFSIKPNFSQK--ISLFEAVQNGLVTENGKIIVDKNKPS---LSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFIS---KSLLKDLTVYCGITN---------GNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEIAINIDQTECNLFENRKLYQTITTVYDSKQNEYI--------SLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIID-----HLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDLFPEF---------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVY---GVEEALAKNILDHPQS-NVTVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTL---ESIKRNYFGDDQDSKLIQTVKDASIRQELPLSVA 7316 N + + SQ+ +SL E GL + ++ +D S L+ A G I +LI+ P+ Q +TL AI G+++ K+ + ++ T E SL EAY ++FIS K+L V G+ + G+ +K+T+ +AI +LID + +I S Q +++ E ++ + ++ + I + ++D + + +D + + L Q + +D I +L++A + ++ + + + +AI + T+ + VF+P + +S QAV++G + H+ + I + G + +N+AI G +++ + +E+ + D I+ GI+ P EKG+V+ S + LT+ +A G + +L T I+ G ++ +GI T P MT+ + ++++ D + +G+ + + EAI+ +FDP C ++D+ +++ DA N+ L +F P K + ++++ + T + + N + G+ L D +S ++T +TD + KT I +D KT+K L E++K+ D D+ I KD++ Q +P+S A Sbjct: 5121 NIAWHVSTGLSQRKGLSLTEVFHQGLFDPSSQVFIDAGTGSVQGLTLQSAIESGLIDSERTLINLPSS-------NQPMTLSDAITQGLVNPKSGEVMDVSTGESISLLEAYNSEFISDSAKALTLSEVVQLGLYDDQTGLITGPGSEKKITLREAIQHSLIDPSSKEIKHPSTGQMLTLQEAVEQNLLDLDSGELLISHSGERINLATAVD-MGVILDTSAIPPY----LQQLVEGFWDKSSGRIIDPVSGKMLTLEKAIETGILDPNKLLLRDPETNEAVPLLNAIQTGIVDTSTGR-----------------------VFDPTKGKDISFDQAVKEGRVIQTQLLHVPEDEDIHMESG---NKGLNKAISDGILDSTSKIYVPETHEM--LSIPDAIALGIVDP----EKGVVN---------ISQKQLTLQQAGHAGLLRKPELP---RTFTQAISCGALNPSTGIYTDPVSGRQMTMLQCMDNDVFDSTVKEFQDSWSGKEVTMSEAIQLAIFDPETCTVQDSKTDERLSITDAQNKGLLLQFRTPGTSENSTPKLKPRTGKQKSIPPPLTVITTAELSENQQQNDFSSAGIASKLQVQRRDRERSPSITEAVTD--GLLDTKTNYI------IDAKTSKRLSMSEAVKKGVI--DTDNTFI---KDSATGQLVPISEA 5736 HSP 8 Score: 90.8929 bits (224), Expect = 1.802e-13 Identity = 247/1256 (19.67%), Postives = 458/1256 (36.46%), Query Frame = 3 Query: 4743 KLSIIDMLKLNVFNIFNGTFNVDCFFEPLTISKAVNSQIIDRKVGGYLNCLMISSIELLHSPPTVISAIYSPKELKIQPPXXXXXXXXXXXXFNPIS-----DKQIKFLDPITNTELKYTDAIRYQYINDDISEILFVDP-----SENSFHLTTKEA------VKNKFFDPESGNIFD----HNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVD-KNKPSLSFLDAFNKGYIKLNESLISGPN-----QEIIHPNL-----------------TQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQ-----------IFDRSNNQF-----------ISINEGYYDKII--TENQYNRI----VFLTCPLIKFSISIDEI--AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFI-----QTNNEKSKERVXX----------XXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSG-NYKIINDFGFVIDIPINEAILSGYIEAIDED-------VKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP-TINDLITQGLVDFDSGIV-----TLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCE-IRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNVTVYMTDVQNSVQ---NKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQDSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENN---STQLFIINPNTGRKLNLEEAIKENIYDPVENMIR-SVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHGLLH-TIMKTRQYMPLSCPFTNVHIRTIEEEMNFSIPQS 8177 +LSII + F+ G +TI +A +S + + G L L+ + + + + T I I + K+QP L L +S ++Q F DP T + +AI + ISE++ P SE S H+ T + V++ + SGN+ H +D I AR E + + +L ++S++L+ +++ S + ++ + + I+L +A+Q L++ + + VD + K S++ DA +G+++ +E I N+ T K T++G +ID + + Q L + + +I+++ + G KL I AI E L+ I +G + +R Q ++I+E I+ + QY VF I+ + I E+ + D + + R+ TI V D+K + IS+ EA K+ ++ G+Y + K S ++AID F+ Q E+ +E+V +E+++ I +V +P TK+ ++ AV+ GI+DH G Y I +N ++ + + + + + I DP +IS A++ G++DR + + + +++ EA + G V + K P I+ L+T + + +P V + ++ D + P + + +P+ E I ++ A+ LF + +T FRDP +D + A+A+ +D VT T +++ +K + IP K V+ T +E + + F + +R + +ME+A GL + G E + T +FI++PN+G++ L AI+ I D R S + S+ ++VK GL+ + VYN P TG+ T L +G + L +R++ L+ +SVYD + + + A+ + +I YI+ KT E + + Q GL+ T M LS ++ T++ SIP+S Sbjct: 2117 QLSIIRSTQRGFFDPTMGQVRDPSLGRVMTIEEATHSGVFTFEKGQEL-LLLTAPVCHITTITTKIHPINQFEHPKVQPSRELAVAKKKLTLSQAVSRGLVDEQQGTFTDPATGQKTSVENAITSGRLGL-ISEVIQAHPMDFDVSETSHHVETGKDSRMEVDVRDSYKQETSGNMQTFRETHVKDRKIA--RARVEEEDDSDEEMEEEIL----------------TLSKSLLHDLLNAKSGYFLEKSTREYITLLDALQKELISRDSAVFVDPQTKDSMNIEDAIRRGFLESTGHYTDALGKRMSLEEAIQKNIVIFRNKEGGVITQALKETHKFTVIG-----VIDAQTGAHLPVGKAIQLGLLDQSQGLYITRNRM-----------GQPVKLPIRNAIQEGLVIIDSGATRVTRVEETQTLSERITYQIKAVKDPIFRTPMAISEAVKTGILNPSNGQYTNTETGQVFQLSEAIEKGLVIAEVVKGDSTDGSGSKIVTRRQTTFTIKAVIDAKSGKQISVTEAMKKGILDQVQGVYINNKTYETLSLSEAIDKGFVIAEAGQLKREERQEKVSSLHIEDDLEEVASEEVAEQVQKIVIRTVTDPRTKKELAYDDAVQQGILDHARGLYYNPTTGRSMAIADAMNSGLIQAEVTMVTREAGMSVSTARGTKDGFDIESVVDPRFQMVISVDRAMKAGILDRDLTTYTHPWTGLQVSVKEAVERGLVNPQD---KSPFHISQLVTTVFQELEQKQAEEKRNAMPEDAVEIKIDHQAKETDTDSITITMDAP---------KVVSKKTGEPVSSEAISIEVTSALSFKSAVKLGLF----------------------NTETGKFRDPASDETMSLNFAIARGYIDPDAPAVTDLPTGKSYTLKEAFDKNIVIPYSGK-VNRNITNFMEIVLDDIF------------------------------FSQTSRSLNMNMEDAIKCGLLDTSSGAFHHPIKAESVTIGRAVEKDYICGTSVFIVDPNSGQRFTLAHAIRAGIMDSEIGEFRDSQSGRKLLSFTDAVKSGLVES-----------------VYN---------------------------------PVTGEVTDLSSGEK---------VLLDRAIKLGQLDANE-----VSVYDFDVGRRVPLDVAMRKGIIERRSGNYIDQKTGEKKSAKEMAQLGLISITGAPVLHGMSLSEAIQSI---TVKRTAKISIPKS 3204 HSP 9 Score: 82.0333 bits (201), Expect = 7.922e-11 Identity = 126/568 (22.18%), Postives = 235/568 (41.37%), Query Frame = 3 Query: 6396 GFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIR-DNCGHIITLNDAINEDLFPEFVPTDKNKI-TFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILD-------HPQSNVTVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQDSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHGLL 8072 G V + + AI SG I++ E +I P S ++ DAI +GLV+ K + + + +++ EA + F+ K T+++++ GL D +G++T P E +TL EAI + ID +KHP G+ + L+EA+E +L D E+ + G I L A++ + D + I + + L +G+ D + DP + + +E+A+ ILD P++N V + N++Q VDT T + + K +D Q VK+ + Q L V DE I ME+ + GL N++++ I ++++++++ P T L++ +AI I DP + ++ + + +++ GL+ R E + Q ++ ++P + DP +G+ T++ ++N VF + + +Q D + +T EAI + + T + KT+E +++DA GLL Sbjct: 5160 GSVQGLTLQSAIESGLIDS----------ERTLINL--PSSNQPMTLSDAITQGLVNPKSGEVMDVSTGESISLLEAYNSEFISDSA---KALTLSEVVQLGLYDDQTGLITGPGSEKKITLREAIQHSLIDPSSKEIKHPSTGQMLTLQEAVEQNLLDLDSGELLISHSGERINLATAVDMGVI-----LDTSAIPPYLQQLVEGFWDKSSGRIIDPVSGKMLTLEKAIETGILDPNKLLLRDPETNEAVPLL---NAIQT---------GIVDTSTGRVFDPTK------GKDISFDQAVKEGRVIQTQLLHVPEDEDI---------HMESGNK-GL-------NKAISDGIL--------DSTSKIYV--PETHEMLSIPDAIALGIVDPEKGVVN--ISQKQLTLQQAGHAGLL-------RKPE---------------------LPRTFTQAISCGALNPSTGIYTDPVSGRQMTMLQCMDN-DVFDSTVK----------------EFQ-----DSWSGKEVTMSEAIQLAIFDPETCTVQDSKTDERLSITDAQNKGLL 5610 HSP 10 Score: 77.0258 bits (188), Expect = 2.359e-9 Identity = 219/1157 (18.93%), Postives = 489/1157 (42.26%), Query Frame = 3 Query: 14700 RVKKQSESTTKA---LESQQQQ----LDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILAN-IEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRIT--DSYQP-SVHPEKLDEELGVFDEILYDL----DKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLA-----KISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWF---KEVNNRLF----------ILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIK-NQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGK------AIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSD---SSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIK 18041 R+ +Q E +K LES QQ L E ++ F + + +W +T + + + + D + + E+E+K L +++ +L+ + +S V K L N +E K ++ K I R DL+ + E + CA+ ++ ++ +T DS QP S L ++L + + ++ D+L++ +DK Q + + PS A+ ++ L TI+L+ + LEK A K+S N+ ++ + + + ++ + W L+ E+K M L V + K ++ L+ EI + ++ +G+ L++ V DV++ + + +AV + +D + L+T LE+M KL E+F K+++ L LG + +R L IQ +E + ++P+ I+ +L L N K +Q+ S + +++ + +L + ++ + + V+ + E L + D + +E L + + A ++ A+V++ E + ++ + G ++E L+K + + + EL + + F+ +++ ID + E GG D LK+ + +TF K +++ + E + S +E D+E L+ KW+ + R++ L+ A+ F + ++WL TE+ + Q+ S Q++ + L++ + + + + K+ + L ++ D + ++ I R+E++ + ++ER ++LD AK F++ ++D + + + + + KIR+Q+ KE + + H + + G +L ++ + E + L++++ +L KS +R + +++ L L+ ++DA L L +EP+L S K + +Q +N + + H + K+ + ++ IED + + + + + ++K ++ +K ++ E + + L ++F ++ ++ T P ++ + +H + + N+ K + G ++L E +G+I+ ++ +K Sbjct: 7401 RISQQLEEISKKWNNLESSLQQRENTLKEVQTVSAGFYDAIQDIGEWAPKTMDRLSRQASISSQADIMREQERELKDLEEEAKEKTKILEDARNAYGKISDKVKDQSTKQDLKNKLEMMDKSLSDTKRRIAGRKADLK---VAMKEGEQFTQSCADLMDWVQGAMTELDSGQPVSGDDLTLKDQLRQHEALQKEMDDRQDQLKLLLDKGQQVLTSTPPSPATADLQNK--------LDTIKLQWDALEKKATHRKRKLSDCNE----KSSAFHQSLDHMTT-----W--LQFAEEKLEMMEPVA-------LERMKVIQQHKDVQTLQTEIVRKTHNHESLNTQGQTLMQNV-------DVDK--QVVADQLDAVNQRWDSLNKAVDDR--LLT-LEDMSQKLHEFFDLIKDLSTSLSKYEDKLSSHDALGAVAKGSR-YLHIIQSLQEEVHSMQPQ---IDYTQELAQSLISAGPANAKTSQITSRVDEVSERYEKLAQEVDSWLASIETGSQVVTGAQQQVNTVGRQLQGFEEDLEKMDACGRDPHVVEQQLQELQAFSAQISEGAAAVNEAEERCHNVMSQGYIGHGDPMLAQVEDLKKQHSRISDRVAQRQGELSGMMNKLDDFHDSLRQLHTAIDRAAEEQESQNPVGGNADN----LKKLLQELKTFEKKSLEPIQKQLEVVSKQGQQLVSSAAPGVSTSGLECDIESLMDKWNELNQKVRDREAALDDALLQSGKFSEAVSALLDWLGETEELMEHQKEPSADYKVAKAQMQEQKFLQKMLEDRQGNVEAIKKIGSKLS--TEDSDGQQVSAQVNDIVKRYEELKAGATERRQSLDTMMTVAKEFQEKLEPVIDWLDTTEKKMASAEPVATESEKIRQQLHHQKEVNEEVADHGEDLAAALKKGEELLQLCNGEERAHVQEKLDELKLRYSALNEKSADRLQQMDEVLPLAEEFEDAHGKFLDLLNRLEPELRGKDMSGKEGENQLEEIQAQMNNLVPILTAVSQTGHPLSKLAIGSAG--------AAEIEDLINKDTKRFEALKEQVDKKAEKINFSKQRSQELLKDISDLMDWFEQTGRLIQ--TAQPISSDPGVLKEQLQDHKALTEEMNQNKGKAREVVTIGRKLLRETSIEDDGTIQDKMDDLK 8496 HSP 11 Score: 70.8626 bits (172), Expect = 1.868e-7 Identity = 110/488 (22.54%), Postives = 212/488 (43.44%), Query Frame = 3 Query: 6444 IEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRS-MLKHPDNGRHICLREAIENDLFDPIRCEI-RDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNVTVYMT--DVQNSV---QNKTLEIPNEEKFVDTK-TTKTLESIKRNYFGDDQDSKLIQTVKDASIRQ-ELPLSVATDERITAVNRKPSNSMENAHSLGL-KSPKLSTNESLTSNI--TSLTGSNTENNSTQLFIINPN-------TGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLE-EKIIQRNCVVYNYYYVHKGV--GVTAKLT-NQMLTENQIDPINQLIKDPKTGKSTTLINGLENG 7838 I +D+ ++S + + FKD SG ++ DA+ KGL++ + S I+T+ EA L L K + T+ + I Q + D +G V P +TL EA++ I + + + HP ++ L+ AIE L D +I + G +++L+DAI+ ++ + I+ EA EQG +D + + +P + EEA+ +L + M+ D +++ Q++ ++ + + D +K +++ ++ D + +K + +K A R+ LP A + + P E + + L K+ ++ E+ T S G T + + ++NP+ +G KL L+EA+++ I D ++ G +++ ERL ++ +R + + KG G LT L + I+ +I DP TG+ T+ + G Sbjct: 5821 IHTLDDAIRSGQIDFNLSVFKDLQSGQMLPVEDAVGKGLINPSTGQV-HLPSGHIITLAEA--LERQLITKKKANFLTLGEAIGQEIYDPHTGHVADPESGQEITLQEALDREIIHPEHAGIFIHPVTQENLTLQGAIEVGLVDGQAGKIVHPDNGMLVSLDDAISNG----WLISSATPISLSEAKEQGLVDFSSGSIVEPTSGQELTFEEAVKAGLLQDKNVDTLRNMSAEDFDSNITDLQHEAFKLEAKSESHDAADMSKQIQNTRQVKSLDMKGAKESEKIKPAITRRPRLPSPTAPKSPL--LEAMPG---EQCYGVSLSKALEVGLYETKTGRFYDPSSGGHVTLHQALNCGLLNPSGREILDQSGAKLTLDEAVQKGIVD--------------------LRKGFLIDPNTGERLHMDQAFERGLIAPS----EKGEVNGHVQGLTLADALQQGLINTTTGIITDPVTGRVHTMGEAVAQG 6272 HSP 12 Score: 69.707 bits (169), Expect = 3.770e-7 Identity = 60/247 (24.29%), Postives = 115/247 (46.56%), Query Frame = 3 Query: 5124 SEILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFD 5864 S +L P E + ++ +A++ ++ ++G +D + ++ LH A G+L+ S +I+ D + K ++ EA+ +GI+D F I PN +++ + +A + GL+ + K V+ + L+ DA +G I +I+ P +H T+ A+ G+ID I+ IT + S+ A ++ +++ T + + N LTI QA + LI +K Q D Sbjct: 6116 SPLLEAMPGEQCYGVSLSKALEVGLYETKTGRFYDPSSGGHVTLHQALNCGLLNP--SGREIL----------DQSGAKLTLDEAVQKGIVDLRKGFLIDPNTGERLHMDQAFERGLIAPSEKGEVNGHVQGLTLADALQQGLINTTTGIITDPVTGRVH-------TMGEAVAQGLIDGDASMVIDPITLKPVSVSVA-----LASRIMEPRTGKLRLPDKFN-SLTIEQAQEKGLIILKGKQHGD 6337 HSP 13 Score: 66.2402 bits (160), Expect = 4.826e-6 Identity = 80/326 (24.54%), Postives = 148/326 (45.40%), Query Frame = 3 Query: 5019 FNPISDKQIKFLDPITNT--ELKYTDAIRYQYINDDISEILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILS---KPIS---ILQIVLEKDEFPFLVDINNEKS-SISEALVRGIIDGNSEFSIKPNFSQKISLFEAV-QNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFI--SKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCP 5960 F+P S Q+ F+D T + L AI I D L PS N +T +A+ +P+SG + D + I L A +S K ++ ++Q+ L D+ + +EK ++ EA+ +ID +S+ P+ Q ++L EAV QN L ++G++++ + ++ A + G I L+ S I Q+++ G D + + I+ ++ + +L++A E + +K LL+D NE + +L AI ++D TG++FD + + IS +D+ + E + + L P Sbjct: 5147 FDPSS--QV-FIDAGTGSVQGLTLQSAIESGLI--DSERTLINLPSSNQ-PMTLSDAITQGLVNPKSGEVMDVSTGESISLLEAYNSEFISDSAKALTLSEVVQLGLYDDQTGLITGPGSEKKITLREAIQHSLIDPSSKEIKHPSTGQMLTLQEAVEQNLLDLDSGELLISHSGERINLATAVDMGVI-LDTSAIPPYLQQLVE---------------GFWDKSSGRIIDPVSGKMLTLEKAIETGILDPNKLLLRDPET--------NEAVPLLNAIQTGIVDTSTGRVFDPTKGKDIS-----FDQAVKEGRVIQTQLLHVP 5437
BLAST of Dystonin vs. TrEMBL
Match: T1IVF3 (Uncharacterized protein OS=Strigamia maritima OX=126957 PE=4 SV=1) HSP 1 Score: 931.784 bits (2407), Expect = 0.000e+0 Identity = 665/2376 (27.99%), Postives = 1237/2376 (52.06%), Query Frame = 3 Query: 12444 NRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGA--------------FSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSD--------LKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLD------EWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQR-LEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALM-IQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPL-------------------IPIFDRSKRM-ETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFK----PATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQ----PVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGL 19397 +R++ L+ +L + L S A+ + +++ +L E +D+ DL+ ++ Q+ ++ + + L +L+ ++ ++ K + K L ++ ++ I+DR S + K + +K ++F D + E + K IG F ++ ++PL KQL+++ IG + S + +++E +++ + ++ L + +++ E +D+ L++ K+ +L+ +++ + + ++ PS +Y K+QL + L L RQ+S+ L + G ++ N + ++ Q++ +L++L +++ L A+ + ++ + ++K F+D + P + WLD EK LA+ +T T D +++K+I ++++L +D + +L + + + ++ + + +K+ L D+++ + L + L ++ +N + E + ++ V + +D +E + +E+ H++ ++ + G ++ + S+ +D+ + K++ L F E++ A L + ++P++++F ++ +L L + + + DS + ++ ++ LENE + ++ + +L + E + VE + + KRF + ++ +KA +I ++ ++ ++++ ++ + E++I E +D + D +L + L N Q+ + + +KK++R+ ++ L +LK + V + S +LE +A+PLA+ F ++ L W+ E E+ + Q+ K + + K L S + KPLLD + K+G L ++ + + ++ RY +K ++ LE L+ ++ +K+D N L N D++ ++ S HPEK+ E++ ++ DLDK + ++ + K +D +V+ + +KL K++ +Q T + + + + + +A+ FW++L + + E+ L + + +++ +++ + +L+ EID + ++ + + G++L+ P++ P+V++ E+L +E V + + R+Q+LI +E+ D E+ + + LGPL ++ V QI + K+ K++++P +E +N+ +LT+ + P + L IN W LL G+ +RQ +L+ LL LG+F A+DE I WI TE +L ++K GD ++E+ LA+ K++ DM+ Q SV + ++I++D S TQ+ L +L W EL++ A A+ ELEDALKE F + Q++ + ++ S L K GGLP++A+EQL RFM++Y ++E ++ + K+S++ ++ +++ L ++WD V N A +K +LE A++ FH + FI+WLT E +++ +PVSR++ TIL+Q+E H++ ++D+ +HRE MLNLDK THLKY SQK D++LI+NL+ S+ HRWE+VVS+S+ER+R LD+GYKEAK F D L++ + + L+ T+I P KI+ Q++KHKEF LG YD+ R G L+++AP D+ I ++++L+ KW S+C KS++R++ L +ALL SG +KDA+ LL WL +E L + + GD++TV T++++H +++LR R ++ + + L S ED I+ Q+ EL++ W+ + KL++ K++RL+ A QA E + N L E+ S +E +LR P E L I+ H F + E + EIL A+P+A IKH+I II+++W ++ W++QR L DH+ L + L +LL WL E TL+ E++ L + + EH+ F +T KQ + + I +K + PP R +RM +T+ +P NP+ +L KW+ VW + + R++RLL+ ++Y KE++ MK+FNF++WRRR++ MNH KSR+MDFF + D D+DG++ R EF+DGI+ SKF+TTR+E+ VAD+FD + G+ID ++F+ ALRPDRE + +PA ++E I DEV++ + KCTC +K+ Q G+GKY+FG+++KLRLVRILRS VMVR+GGGW ALDEFLVK+DPCR AKGRTN ELRE+ +G +M+PFK K + T+ T+ +P+ + P++ R P+ PR S +S S S + S RT + +P Sbjct: 1385 DRFRQLAKNLEDRCSGLESASHAVAQFNEQVKSVHHDLTSLEEALDSMGPVGRDLNIVKKQVDEIKKFLNSVDSEKGDLDDLERSARDMIDRGFAPDPKGLKK--QLESLRRQL-GRIEDRAQS---REKDLDGMMTKLSNFYEDYDMVTGEIEGGVNEEKSFKPIGGDIDTVKAQKEEFKLFCKRHMEPLTKQLDDMNKIGQGLIQSAASNVSTQNLESDLEKMNDKWNDLKEKLNERERRLDVALLQSGKYQEALQGFLQWLNDTEDMVAHQKAPSADYKVVKAQLQEQKFLNKMLLDRQNSMSSLFQMGEEIASNAEASERHQVEGQLNDLVQRFDALTTTAQDRMENLEKTLPIAKEFQDKFTPLVDWLDRTEKKLASMETIAT-DEKKIQKQIAQHQNLHDDILGHKPAFDQLADVAQILMSLVGDDEAQNLADKLQDLTDKYARVVEDSENLGLFLAQSREGLGHFSLNLNDLLAWIDEIEHRLTRFRVLSVFVDKLQDQLDELTEVTEEIADHQQQVEGVIANGHEIMKHSTGDDALLVKEKLDTLQQRFLEMTNRAADLLRHAQEALPLSQQFHQSHTRLVEWLIEVESQLPSIDSAGLVLQDKEIQRLENEIQEFKPILENVNHVGPQLCQISPGEGA-STVETLMSRDNKRFDAICEQIQRKAERIQLSKQRSSEVIGDIEEFLDWFRDVERQILE-ADPVIPDPDQLLMLLKEHKALNDDINSQRGRVRDVTSTAKKVMREQTSNENTPFINEKLNNLKDLIANVSQLSSDRLSSLE-------QALPLAEHFYDTHLELVQWMDELEQEAMLLGTPVANATQIKKQQDKTKTLLQSIAEHKPLLDKLNKTGSALVKLCGEDECGKVREILDADNARYGGLKVGLRDHQNALEQLMQETSQFADKLDGLLNALTNTADQVNNAEPISAHPEKIQEQISENKAVVEDLDKRSSAFEAVKRAADEVIS--KAGGTRDPAVQ-------------DIKKKLDKLNKLWDQIQFVTGDRGKSLEDAMDVADRFWDELNAVMNALKELQDSLVSQEPAAVEPQAIQQQQEALHELKQEIDQTKPEVEQCMKTGQKLMTLCGEPDK-PEVKKNMEDLDHAWENVTTLYAR------REQNLIEAMEKAMTFHDTLQNILEFLETAEEKFGNLGPLGSDIDAVKKQIAQLKDFKSEVDPHMVHVEALNRQAQELTENTSPEQAQAIKEPLKDINRRWDDLLRGVVERQRELEHALLKLGQFQHALDELIVWIAKTERTLKSMKPVFGDPQTIEVELAKLKVLVNDMHAHQNSVDTLNDAGRQLIEQDKGSEESSKTQKKLTELNVRWTELQQCASARQRELEDALKEGQAFNQEIQDLLLWLSDVDSVLSTSKPVGGLPESAREQLHRFMEVYNELEATRPRVESMQQQGTDFVKRSTEGAATNLQHNLKTLRQRWDNVTNRANDKKIKLEIALKEATEFHEALQNFIDWLTKAEHSISGLKPVSRVMDTILQQIEEHKSFQKDVGTHREVMLNLDKKGTHLKYFSQKQDVILIKNLLVSVQHRWERVVSKSAERTRALDHGYKEAKEFNDEYSELINWLDKSQTALDDLTTISNDPEKIKHQLSKHKEFQRTLGTKQPDYDACMRHGRTLKERAPKSDAPTIQGMMNDLKSKWNSVCAKSVDRQRKLEEALLFSGQFKDAVQALLDWLYKVEKNL-EPEQPVHGDLDTVTTMVDQHKSFKEELRGRSTNMDSVRKTSRELSKTASPEDVKNIQAQMGELENMWDKIGKLSDTKQKRLDGALKQAEELHKKVNILLEWLSDAEMKLRFAGALP--ENVSLTQEQITEHRKFLNEMTDRERDKDSTIALAQEILKKAHPDAVPVIKHWITIIQTRWEEISMWAKQRKQRLDDHVASLRDLADTLTELLDWLKKKEKTLVDLEAKPLPDDIPVIERLIEEHKEFTEQLTEKQPEVERI---TKTRRPPARDPSPKGRKDTKDRLGKDPTGSLKRGQRMPKTSTPAKPSTDPYIKNPQARELFDKWRHVWLLTMERQRRLLEKLKYSKELDKMKSFNFDEWRRRFLRHMNHKKSRIMDFFNKLDKDNDGKLIRDEFVDGILRSKFETTRMELNAVADMFD--RGGYIDIKEFVDALRPDRE--RDRPATDSEKIEDEVQRLVMKCTCQYRFKVHQVGEGKYRFGESQKLRLVRILRSTVMVRVGGGWVALDEFLVKNDPCR----------------------AKGRTNIELREQFILAEGVSQSMSPFKAKSPTSSHSSQSGTRSGTSGSLPA---AGPITKIREKSSRSVPMGQPRSSSTAGSSDLSGQSFSEGDSSGIGS-RTTRKTPTPSF 3686 HSP 2 Score: 150.984 bits (380), Expect = 1.218e-31 Identity = 262/1253 (20.91%), Postives = 562/1253 (44.85%), Query Frame = 3 Query: 8358 IEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDL--EETTNLLKTHT---NQTHKELNNR-SRLLIAI---IDEFDQFINRLNDCTSAHDKLKLS-IDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDK-------INKLEEQ-RKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSRE-------ELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIE-------DSLQNSIKSLE--AIGNT----RENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIG-SLSLDPKYINEQ---ERLIQTILAEISSRQPFLENVLMNN-----ASRNEPKLKELDDKIK------QKLLVASNIEAK-VNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQG-FPLGGDQQAKLTSPQRK--------PSKIKAELYTQPLSPTSITKQPTTANRQXXXXXXXXXXXXXXADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELL---SVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDK----NDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNE--EKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWI 11900 +E + +E ++ +E++L + V NE + + ++ + + E QQ V + ++ + + E K++ E N L+ H+ N+ ++ N+ SRLL A+ +DE ++F N L + +++ IDK ++ ++ L+K++ +K ++ ++ D+R + + KF+D+ IN Q ++FS L + PL D EI +NEV+ +DL L++ + + + L +++++ + E ++ ++ K+++ ++ D L+ ++V+ ++++ ++ D+L + I E AI NT + L + + NE L L Q+ Q + + I+ + WL +++ + +N SL + ++EQ RL+Q A+I R+ + ++ + + +S N K+L+ K+K +KL ++ + +N L SF V V DW+ TE L + R D ++F +++EI K+ D + K L+++ + D I +++LE+ W L + ++ R+K+ + Y L+ ++++ L E + P+A+DL + + Q ++++ + E+ I + +G+ YD + +G P ++ TSP +K P+ K+ T+ SPT ++ Q ++ SG S S D + ++ + ++ +I RY IG +L +R S++ + + ++ S L + LL SV + ++ I +++ +P + T +LL+ + VPG L+ ++ + ++++ K + + MK F + +++N + +K++M+ VLGPV + Q+QQV L DE+ G + + L G+ + PTS + I TL+ ++ + L L +RE N+ ++ G ++DFY IN + + L + + D L ++ +L++ + +L + E+L + L + D + EIK+K++NL + ++ KID+ + V K ++ + W++ Q + L L V + +++ + + ++ K+ +V + LN+ + K+P ++ + DKLA + + + + + + Q A+ K ++ +K W+ Sbjct: 11 VESISKFLEWIAQVERRLANQEPVRENENDLRSQINTLKTLKEELDDQQRPVAACLDQVRQVV---------EFGKEVLSAEEMNQLQRHSTDLNRRYQTCNDECSRLLKALASALDELNKFKNELLPFQKWLREAQVTLIDKERSLGDLDRLKKNVDSIKSFSSDVIAHQADLRFITMAAQKFLDESKEYLKEINTYRTQLPQRFSHLQQ-PL--------DSEIKRTVNEVSIAFQDL-------LARANKLSDRVSGLTDRERQYKESVERAKSWVTETQNKMTKLMNEPVGSDPTTVQEQVDRTKALSVDIVAQKRLVENVQQMGKALMDALSSDISDAERDAIYNTLQWLEDQYSLIQADVSARSNE-------LEMALVQL--QGVQD-----GIDGVLTWLNDVEAQSRNASKPASLIREKLDEQIQEHRLLQ---ADIEGRRHTVNSIAVESQDLIRSSSNVRVAKKLESKVKDMTGRYEKLADKNSKRGEFLNQVSVQLDSFLVLVTRISDWLLEATESLDE--TARSDADEFGRRIEEITRQKNSKKTDFDGLVHDGKTLIAKKDVTDSTYIRDLLKSLEQQWKELTDALSDRAKQTKQMADQLNAYEVLRVQVLQWLKTMEIRVDGLEPVAVDLDSCKKQADEVKVIVREYQGYSSTIEKVNDLGNNYDRLSRGDRPESPTRRRVTTSPTKKATSPVKKTPTSRKSPDDTRSPSPTKVSAQSPLSSASSGFSSRRSSQ-----DNIGNLEDLTPIQQQLTEINHRYEMIGVKLNDRTSELDTIREQVKKHLDVLRQLSTWLTGK-ERLLPKDSVPSTREEAERHLKNVKNILDEMAEKQPQTDTLKTQTNELLKQKPNVPGASNLRQQVTDFVVHWEEVQNACKSRCDFMDD----MKNFFDSAGNLQNWLEQKDKMMAVLGPVASEPRLVMNQMQQVEVLRDELSGQQPQLNRLNEYGEAALDKCLPTSPDGRRINATLNTMNDHWNKLMAQLDERENNLEAVSGSNRDFYAKINQLQENLQKISDDFDNLGDIGPNKELQLNKLRNLEDQLENQRPLLADVESLGEELCNILEDSTSKNEIKSKLTNLEKTYNQLTKKIDNRKAELESTLRETKVFEDKCQEMQDWIEDFQHTV-LRDLHVSADKDIVRKQVQEYESVYREVLDKEHEV---HMLLNKGQDALAKTPVKDAQMLRDKLATMKTRWDRLKKEAVDRNTRLQNANEQAKKFHSLLDKFTPWL 1205 HSP 3 Score: 130.183 bits (326), Expect = 2.169e-25 Identity = 344/1695 (20.29%), Postives = 667/1695 (39.35%), Query Frame = 3 Query: 13329 KAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVS-IDT---KNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAA--INCKINILHNYFDEISVSA--------------LKKL--SLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQV-----GERNMEILENETNSVE------KLVCQAR--------NDLDKLK-----------SVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCM-------EVLSNFEQKINEMSDQINN------DY----SELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDK---LQIFVDKLQIGIENCSPSRKNANDKDDSVE--ISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIE------DLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPD-VEQAEEELKRNFEAVRSSCEQ-----QITNIDRQQS--LITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQ-VNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATEN----------SLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKM-----ERKAAEIIKEDVSSLG------HEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIE---IDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQ--SEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHEL---RQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDL 18059 ++ D LIN + + +Q LDEL ++ L A ++ + ++ F D L E LA+ D+ DA + K ++ K L + ++ + +K + DG+ + S DT K + DRF + K+ ED G ESA + E+ ++ ++ S EE L ++ VG DL + + D +N ++ D++ SA LKK SL I +R LD ++ L+ + D +TG++ E++ + + + ++V+ KL C+ +D++K+ S E+ LEK+ D + + KE LNE +E LD + E L F Q +N+ D + + DY ++L+E K LL N S++S +++ A S+ ++ ++ + ++ ++ T + + + L++ +P+AKEF + L DWL TE+ + + D ++ K + + L + KP D + L +V + +N+ ++D +Y + E D E+L L + E + + L ++ L DEI + L + L +FVDKLQ ++ + + D VE I++ + +K + + + LQ + +E + +LL A E + +FH+ L IE +++ + + K I+ L EI + + ++ G QL + +P E VE + F+A+ CEQ + + +Q+S +I +EE LD WF++V ++ P+ + +L +++ K L +DI + + + ++ + N +N L + D A + R L+ L F+ E ++W+ E + T IK + +L +A+HK + +N + +++ K+ K EI+ D + G + LEQL + + + D L AL DQ ++ I P+ +EQ+ + K + E + E+ K+ + A++ ++ L K WD ++ + R LE A++ + F ++ +N L + +L Q P + I +Q EA LK++I + E+ K L + + D ++ M + H WE V + + R +NL ++A F D + +L+ + + E +G +++QI + K+F + H + ++ R +L + + ++ I E + ++ +W L +ER++ L ALL G ++ A+ L+ W+ E L S K GD T++ L + +L + + ++ +N L+ Q E+SS + +L EL W + + A+ ++R LE+A + F + L + S + L + PE +E+L M + L ++ QQ G + + + A +++H + ++ +W ++ Sbjct: 1250 RSHGDTLINMADIDQEVVQEILDELRDRWNRLNADAGDRSQSIEEILQRLGDFNDNLRDLQHGLQRCEDRLASHDS--LGDAAKDPKLLERMKSLLREAEAMATGVDSVKDV---ADGLIMDAPSECDTSHIKKSVGDADDRFRQLAKN------------------------LEDRCSGLESA----------SHAVAQFNEQVKSVHHDLTSLEEALDSMGPVGRDLNIVKKQVDEIKKFLNS-VDSEKGDLDDLERSARDMIDRGFAPDPKGLKKQLESLRRQLGRIEDRAQSREKDLDGMMTKLSNFYEDYDMVTGEIEGGVNEEKSFKPIGGDIDTVKAQKEEFKLFCKRHMEPLTKQLDDMNKIGQGLIQSAASNVSTQNLESDLEKMNDKWND----LKEKLNE-----------------RERRLDVALLQSGKYQEALQGFLQWLNDTEDMVAHQKAPSADYKVVKAQLQEQKFLNKMLLDRQN----SMSSLFQMGEEIASNAEASERHQVEGQLNDLVQRFDALTTTAQDRMENLEKTLPIAKEFQDKFTPLVDWLDRTEKKLASMETIATDEKKIQKQIAQHQNLHDDILGHKPAFDQLADVAQILMSLVGDDEAQNLADKLQDLTDKYARVVE-------DSENLGLFLAQSREGLGHFSLNLNDL--------------------LAWIDEIEHRLTRFRVLSVFVDKLQDQLDELTEVTEEIADHQQQVEGVIANGHEI---MKHSTGDDALLVKEKLDTLQQRFLEMTNRAADLLRHAQEALP----LSQQFHQSHTRLVEWLIEVESQLPSIDSAGLVLQDKEIQRLENEIQEFKPILENVNHVGPQLCQI--SPGEGASTVETLMSRDNKRFDAI---CEQIQRKAERIQLSKQRSSEVIGDIEEF---LD-WFRDVERQILEADPVIPDPDQLLMLLKEHKALNDDINSQRGRVRDVTSTAKKVMREQTSNENTPFINEKLNNLKDLIANVSQLSSDRLSSLEQALPLAEHFYDTHLELVQWMDELEQEAMLLGTPVANATQIKKQQDKTKTLLQSIAEHKPLLDKLNKTGSALVKLCGEDECGKVREILDADNARYGGLKVGLRDHQNALEQLMQETSQFADKL--------DGLLNALTNTADQVNNAEPI-------------SAHPEKIQEQISENKAVVEDLDKRSSAFEAVKRAADEVISKAGGTRDPAVQDIKKKLDKLNKLWDQIQFVTGDRGKSLEDAMDVADRFWDELNAVMNALKELQDSLVSQEPAAVEPQAIQQQQEALHELKQEIDQTKPEVEQCMKTGQKLMTLCGEPDKPEVKKNMEDLDHAWENVTTLYARREQNLIEAMEKAMTFHDTLQNILEFLETAEEKFGNLGPLGSDIDAVKKQIAQLKDFKSEVDPHMVHVEALNRQAQELTENTSPEQAQAIKEPLKDINRRWDDLLRGVVERQRELEHALLKLGQFQHALDELIVWIAKTERTLK-SMKPVFGDPQTIEVELAKLKVLVNDMHAHQNSVDTLNDAGRQLIEQDKGSEESSKTQKKLTELNVRWTELQQCASARQRELEDALKEGQAFNQEIQDLLLWLSDVDSVLSTSKPVGGLPESAREQLHRFM-----EVYNELEATRPRVESMQQQGTDFVKRSTEGAATNLQHNLKTLRQRWDNV 2809 HSP 4 Score: 95.5153 bits (236), Expect = 6.577e-15 Identity = 201/1065 (18.87%), Postives = 456/1065 (42.82%), Query Frame = 3 Query: 14673 LKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRIT--DSYQPSVHPEKLDEELGVF----DEILYDLDKLQIFVDKLQIGIEN-CSPS--RKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNT--RSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNI-DRQQSLITKLEEMRMKLDEWFKEVN----------NRLFILGPLPTETRPVLTQIQKTKEL-KNDIEPKHRDIELINQLGYQLTKGSHPNIKNQ-VNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFM----DIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLD---DIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQ--SEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEA 17768 L ++K+ DR+KK++ L++ +Q AK+F S + WLV+ E + K + ++L K +EI+A N D + G L + + + + + +++ + R+N + R+ +E+++ + N+ + + L+ DR+ DS + KL E + + + +D ++ D L + + C S +K+ D DD +L +N ++ + + S++ + ++ E++ ++ +DL +E+ M DLN + V++ KK + +D + D+ + + + +I++ P+ + LK+ E++R +Q+ I DR QS L+ M KL ++++ + N P+ + V Q ++ K K +EP + ++ +N++G L + + N+ Q + S L ++ND W L + L +R+ +L LL G++ A+ F++W+ TE+ + + K D ++ L + K + + Q S+S + + EI +S H+ +L L + ++ L A+ + LE L A F + +D KL + ++Q+ + DI P + + + + +Q++ ++ L K+ V +E L ++ E + F L++ + W+ E L + R +S V + +Q++ + +I H++++ + + S D +L++ + ++ R+ ++ +R+++ R+ +++F + L++ ++ S L ++ + Q +I+ + +EF L ++ +G QL +P + + ++ ++ ++ ++C + + + + + S + L W R +E ++ ++ D + + LL EH L + + + + + A +M + S E++ FI ++L LK NV++L++++ LE+A Sbjct: 1163 LATMKTRWDRLKKEAVDRNTRLQNANEQ-------AKKFHSLLDKFTPWLVQAELKLVNLKPLSFKKNELDKQLREIQAFRNDLSRHSQEYDTVRSHGDTLINMAD-IDQEVVQEILDELRDRWNRLNADAGDRSQSIEEILQRLGDFNDNLRDLQHGLQRCEDRLASHDSLGDAAKDPKLLERMKSLLREAEAMATGVDSVKDVADGLIMDAPSECDTSHIKKSVGDADDRFR---------QLAKNLEDRCSGLESASHAV----AQFNEQVKSV-------HHDLTSLEEALDSM-----GPVGRDLNIVKKQVDEIKKFL----NSVDSEKGDLDDLERSARDMIDRGFAPD--------PKGLKKQLESLR----RQLGRIEDRAQSREKDLDGMMTKLSNFYEDYDMVTGEIEGGVNEEKSFKPIGGDIDTVKAQKEEFKLFCKRHMEPLTKQLDDMNKIGQGLIQSAASNVSTQNLESDLEKMNDKWNDLKEKLNERERRLDVALLQSGKYQEALQGFLQWLNDTEDMVAHQKAPSADYKVVKAQLQEQKFLNKMLLDRQNSMSSLFQMGEEIASNAEASERHQVEGQLNDLVQRFDALTTTAQDRMENLEKTLPIAKEFQDKFTPLVDWLDRTEKKLASMETIATDEKKIQKQIAQHQNLHDDILGHKPAFDQLADVAQILMSLVGDDEAQNLADK----LQDLTDKYARVVEDSENLGLFLAQSREGLGHFSLNLNDLLAWIDEIEHRLTRFRVLSVFVDKLQDQLDELTEVTEEIADHQQQVEGVIANGHEIMKHSTGDDALLVKEKLDTLQQRFLEMTNRAADLLRHAQEALPLSQQFHQSHTRLVEWLIEVESQLPSIDSAGLVLQD-KEIQRLENEIQEFKPIL-------ENVNHVGPQLCQISPGEGASTVETLMSRDNKRFDAICEQIQRKAERIQLSKQRSSEVIGDIEEFLDWFRDVERQILEADPVI-PDPDQLLMLLKEHKALNDDINSQRGRVRDVTSTAKKVMREQTSNENTPFINEKLNNLKDLIANVSQLSSDRLSSLEQA 2165 HSP 5 Score: 92.0485 bits (227), Expect = 7.207e-14 Identity = 98/477 (20.55%), Postives = 224/477 (46.96%), Query Frame = 3 Query: 15663 SQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKN--QVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDIN-SLEMGLAQHKMIRADMNISQASVSKMERKAAEI--IKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDI--VLIRNLMSSIHHRWEKV 17072 +Q + L +K N P + ++ Q + ++E V+++C+ + +D ++ + L W ++ + + +LGP+ +E R V+ Q+Q+ + L++++ + + +N+ G P + ++N+TL +ND W +L+ L +R++ L+ + S +F+ +++ E + + N+ GDI + E+ L + + + + + ++ +E E+ I ED +S +E +L L K++ +L + + ELE L+E +F QE+ I++ + D ++Q++ + +YR ++ + + + K+ + + + + +WD +K A R +RL+ A E + FH + KF WL E L +P+S + + +Q+ +A + D++ H +E D + +H + DI +++ ++ + RW ++ Sbjct: 818 TQTNELLKQKPNVPGAS-NLRQQVTDFVVHWEEVQNACKSRCDFMDDMKNFF----DSAGNLQNWLEQKDKMMAVLGPVASEPRLVMNQMQQVEVLRDELSGQQPQLNRLNEYGEAALDKCLPTSPDGRRINATLNTMNDHWNKLMAQLDERENNLEAVSGSNRDFYAKINQLQENLQKISDDFDNL----GDIGPNKELQLNKLRNLEDQLENQRPLLADVESLGEELCNILEDSTS-KNEIKSKLTNLEKTYNQLTKKIDNRKAELESTLRETKVFEDKCQEMQDWIEDFQHTVLRDLHVSADKDIVRKQVQEYESVYREVLDKEHEVHMLLNKGQDALAKTPVKDAQMLRDKLATMKTRWDRLKKEAVDRNTRLQNANEQAKKFHSLLDKFTPWLVQAELKLVNLKPLSFKKNELDKQLREIQAFRNDLSRHSQEY---DTVRSHGDTLINMADIDQEVVQEILDELRDRWNRL 1281
BLAST of Dystonin vs. TrEMBL
Match: A0A2J7PSP3 (Uncharacterized protein (Fragment) OS=Cryptotermes secundus OX=105785 GN=B7P43_G06713 PE=4 SV=1) HSP 1 Score: 930.243 bits (2403), Expect = 0.000e+0 Identity = 676/2501 (27.03%), Postives = 1260/2501 (50.38%), Query Frame = 3 Query: 12174 QISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASI---AQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAE-----------QKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQ-APGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ-RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTL----------LDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEE-DSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEII--------------TNSKKKTPPLIPIFDRSKRMETNQGI-----------SKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPR---VSQPLSSPRIHQPVSSP--------------RIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQS 19469 +++ TEN+ L+ +L + E K + A K P KL IK + + +K +++ + + A V+AT L+ E++ + +R L + L + L S A+ + +++ + L ++D DL ++ Q+ D L ++ ++ ++N S E+L + +++E ++ + ++D A E+ ++S R S H VT+ ++ ++ +RK+ ++ E K + AF ++PL +Q+E+ +G + G+ +E++++ + ++ L +++ + +D+ L++ KF +L+ L +++ + + ++ PS +Y K+QL + L L RQ+S+ L G+++ ++ ++ +L EL ++ENL A + +A+ ++K F+D P + WLD EK + + + PT D ++++RI+E+ L +D KL + + + + E+ + K+ + DR++ + +LL + LR+ + + + E + ++ V + + ++ +L +E+ +H+ + G +L + S +++ + K++ L F++++ L + ++P+ ++F +N+L + A ++ D E +++ LE + ++ +L + E + +E + + +RF + ++ +K +I ++ ++ ++D+ ++ E +I + ++ ++D + + L + QK + ++ +KK++R+ A D +++ ++ +++ ++ + + L++A+PLA+ F ++ L WL E E+ + + L PD + + + + S + KPL++ + K+G L ++ N +G + ++ RY ++ ++ R LE + +++ ++K++ L + D++ + S HP ++ +++ ++ DLDK + ++ ++ K N D +V+ + KL +++S +Q T + + + L +A FW++L + E+ L++ + ++ ++ ++++R EID + ++ + Q G++L+ P++ P+V++ E+L ++ + + ++ N+ + E L E+ +R +G L ++ V QI++ K+ K +++P +E +N+ +LT+ + + + L+ +N W LL G+ +RQ QL+ LL LG+F A+ E + WI T+ +L +K GD LE+ LA+ K++ D+ Q SV + +II+ + ATQ +L QL + W +L A + ELEDALKEA F+ + Q++ + ++ + K GGLP+TA EQL+RFM++Y + K+E +++ E KKS ++ ++ L +WD+V A +K +LE A++ FH + F++WLT EK L+ +PVSR++ TIL Q+E H+A ++D+ HRE MLNLDK THLKY SQK D++LI+NL+ S+ HRWE+VVS+S+ER+R LD+GYKEA+ F D L LDD+A T +G P KI+ ++ KH+EF L TYD+T R G L+++AP D + +++ L+ KW ++C KS++R++ L +ALL SG +KDA+ LL WL+ ++ LS+ GD++TV L+ +H E+ L R +E + L ++ D++ I QL+EL S W+ V+ L +K RLE A +A + + + L E+ S +E +LR PE+E+E N ++ H F + + E + + +IL A+P+ I+H+I II+S+W ++ +W++QR L +HL L++ + LL++LL WL+ EGTLL E+ L + + ++H F+ + + +Q + D + T +K + P P R + + I SK EP+F NP++ L KW+ VW + R++RL + YL E+E +KNF+++DWR+R++ +MNH KSR+ D FR+ D ++DG + R++FIDGI+ +KF T+R+EM VAD+FD+ G ID+++F+AALRPD E + KP E E IHDEVK+ + CTC +++ Q G+GKY+FGD++KLRLVRILRS VMVR+GGGW ALDEFLVK+DPCR AKGRTN ELRE+ +G +M FK P P + S R V+ P++ R S P R P ++ + P + S L S TP + PG + SR +R S+QGS+ +RH S Sbjct: 1103 RLTDFTENLRDLQHSLQRCEDKLASHDALG-GASKDP----KLLERIKALREETGGLKKPLQSVRQAAGDLVNEAGEHGVDATHLQDEVDNLADRLDDLQAKLDDRCSELQSAATAVTQFNDQVKGLSHDLSGLEHELDAMKPPGRDLKTVRGQLDDTGKLLKKISKAADEVANTVSAGEHLVDSGFAPDTVATREQVELLQRQLGRLDERAKSREEDLDSTLGRLESFYQIHAAVTQEIAEASERVRKLKPVGSEVEGIK---AQQEEFRAFQVSNIEPLARQVEDCNRLGQGLIQSAAGGVNTTSLEKDLEKMNDKWNDLKDRLNERDRKLDVGLLQSGKFQEALDGLSKWLADTEEMVANQKPPSADYKVVKAQLQEQKFLKKMLLDRQNSMSSLFAMGNEVAAGADPVERKGIERQLRELMGRFENLTTGAAQRYEDLQQAMAVAKDFQDKLVPLIEWLDRTEKQVKDMELVPT-DEEKIQQRIKEHSALHSDILHKKPDFFKLTEVASALMALVGEDEASGLACKLQDMTDRYAALVDASENVGQLLQQSRAGLRHLVLTYQDLQAWMEAMEHRLAKYRVLAVHTDKLLEQMDDLADLTEEIANHQSQVDGTVDSGLELMKHISNDEALQLKDKLDSLQRRFNDLTTRGADLLKHAQEALPLVQQFHNCHNRLVDWMMGAEAQLQCADP-----HEEDIQRLEQDIQEFRSVLESINLVGPQLCQISPGEGA-STIEGLVTRDNRRFDAIAEQIQRKGERIQLSKQRSLEVIGDIDELLDWFREVEGQIRD-AEPPSSDPGVIRVQLKEHKALNDDISSQKGRVRDVLSSAKKVLRESAQHEDTTTIREKMEDLRETMDTVSGLSSDRLGVLEQALPLAEHFHETHTGLVSWLDEMEQQVAMLAMPALRPDLITQQQDRNEMFVQSISEHKPLVEKLNKTGEALIRLCNDEEGAKVQDILDGDNARYAALRSELRQRQQALEQALQESSQFSDKLEGMLRALGSTADQVNSAEPVSAHPPRIRDQMDENAALVEDLDKREEAFAAVKRAADDVIS--KAGNRADAAVK-------------DIKRKLDRLNSLWNEVQKATNDRGKSLEEALVVAERFWDELHNVMATLRELQDSLSSQEPPAVEPAAIQQQQVALQEIRHEIDQTKPEVDQCRQTGQELMNLCGEPDK-PEVKKHIEDLDSAWDNITALYAKREENLIDAMEKAMEFHETLQNLLEFLDGAEDRFAAMGALGSDIDAVKRQIEQLKDFKAEVDPHMVKVEALNRQAQELTERTSADQAAAIKEPLSAVNRRWDELLRGMVERQRQLENALLRLGQFQHALAELLVWIDKTDGTLDELKPVAGDPQVLEVELAKLKVLVNDIQAHQTSVDTLNDAGRQIIESGKGTAEASATQEKLLQLNRHWRDLLAKAADRQHELEDALKEAQRFHAEIQDLLSWLGDVDGVIAASKPVGGLPETASEQLERFMEVYNELEQSRPKVETVLQQGQEYLKKSGSGAANNLQHNLRTLKNRWDSVTARASDKKIKLEIALKEATEFHEALQAFVDWLTNAEKILSNLKPVSRVMETILSQIEEHKAFQKDVGVHRETMLNLDKKGTHLKYFSQKQDVILIKNLLISVQHRWERVVSKSAERTRALDHGYKEAREFHDSWSGLMSWLGETEKSLDDLAVEA------TGVGNDPEKIKARLAKHREFQRALSGKQATYDATMRAGKTLKERAPKSDEPALKQMMTELKNKWNAVCAKSVDRQRKLEEALLFSGQFKDAVQALLEWLQKVQKVLSEEGP-VHGDLDTVMALVEQHKTFEEDLASRSAQMESVQRTGKELEAKATPNDATTIRGQLSELSSLWDRVSTLTKKKSARLEGALKEAEQLHKAVHMLLEWLSDAEMKLRFAGPLPEDEQE--TRNQLAEHDKFMREMAEKEHEKDATITLAQQILGKAHPDGATVIRHWITIIQSRWEEVSTWAKQREQRLTEHLRSLHDLEGLLEELLAWLSGLEGTLLTLETEPLPDDIPTLESLISDHREFMENTSKRQPEVDSVCKSRQQVKPQSATQQTKDRKPSRPRTPARASPGREKAPELIPHIGPRFAAKGSKGAEPVFRNPRVKLLWDKWRNVWMLAWERQRRLQEKYSYLLELEKVKNFSWDDWRKRFLKFMNHKKSRLTDLFRKMDKNNDGLIPREDFIDGIMKTKFDTSRLEMNAVADLFDRSGEGLIDWKEFIAALRPDWE--ERKPDTEAEKIHDEVKRLVMLCTCRQKFRVFQVGEGKYRFGDSQKLRLVRILRSTVMVRVGGGWVALDEFLVKNDPCR----------------------AKGRTNIELREQFILAEGVSQSMTAFK--------PKASPGASSAGSQRSQSVAGPITKVRERSARSVPMGRNTGRSSFSGGARTPDSLSDNESTLTRPIRKGSAPLRSSLTPG-GSQPGSKAGSRPSSRPQSRQGSKPPSRHGS 3529 HSP 2 Score: 105.145 bits (261), Expect = 7.750e-18 Identity = 179/872 (20.53%), Postives = 380/872 (43.58%), Query Frame = 3 Query: 9033 YKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQ-------KILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNI-GSLSLDPKYINEQERLIQTILAEISSRQPFLENV------LMNNAS------RNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRK-------PSKIKAELYTQPLSPTS---ITKQPTTANRQXXXXXXXXXXXXXXA--------DYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELL----------SVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEK-----IDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDH 11489 Y+ LS+ + + L + +Q++ + +R L+ K+LS ++ + LN E V+ ++I + S+ ++SLE T I P+ +++ ++ L + + ++ + + ++++L WL + ++K++ SL + + EQ R + +LA++ S +P +E+V L+ AS + E KL+++ + + L + + L F A W + + R ++L+ ++ K+DEI + KQ + + + K LV++ + D + ++ LE W LN L+ + K R + Y +L+ +++E L E + P+A+++ L Q E ++ + E+ I++ ++G+ YD +++G + SP R+ P+K + + + PL TS + PT + S G SS D +L +E S ++ +I +RY +G +L +R++++ S +E K+ D L S L + L +V + +++ I ED+ + L + + DLLR + + G L+ +L + ++ +L D K + + MK F + ++ + K+RM+ LGP+ + +Q+QQV L +E + + L +G+ ++ + P + + + L + ++ +L L++R ++ + S++F +N + D L + ++ +DK+ L E ++ +L+ + +L ++E L E +SD + EI+ K+ + R +Q K+DH Sbjct: 25 YRDLLSRANGLSDRLSGVGGRQREYRDALDKARAWLREAEPRANKVLSEPVGAEPKTVEEQLNKAKTLNNEFVAQERLIDAAKQSVVALVRSLEG-QQTPGEIAALETPVLELEDKYKQLSAALADKCRALDTALVQSQGVQDALDSLMQWLNATENQLKSLMRPASLLKERLEEQIREHRLLLADVDSHRPSVESVAQSAQELVATASNARLAKKIETKLRDVTTRFDKLLDRTVKRGELLEEVHSALTVFSNAAVQFELWYCELLDAIESRDVLKLEIAEYGVKIDEIVAKRDAKQGEFDDMVRNGKNLVAKKDVTDTVPVRDKIKALEGQWKDLNSLLEDKQKLSKARAHQLGAYEKLRDQVLEWLATMETQVLRLEPVAVEIETLRKQTEQLKPMMKEYRDYGTTIDKVNELGNIYDGLLRG--------ERPESPARRRSSSAYSPTK-RTSVTSSPLRRTSHEARSPSPTKSGSGGFSVQSPVSPGGSSGFSSRRSSQDGFHL-EELSPVQQQLTEINNRYGLLGVRLSDRQTELD-------SIREEVKKHLDNLRS-LGQFLEKVQRNIPKETVPHSKEDSDKMAKQMKSIVEDMYEKQSLLDSTKSQVNDLLRRKPVALGADNLQEELTDVVSRWKTLHDRCKDRIKFMED----MKDFHDTHDNLNGWLSAKDRMMTALGPISSDSRMVQSQVQQVQVLREEFRTQQPQLSHLSQVGESVLACLDPNTPDAQRLSARLTSILQRWADLLSRLEERADSLGAAADTSREFDAGLNRLRDALQGISDQLDDLPLDKDPEEQLRKI--ENLERQLEGQRPLLADAEAAGAQLCEVLSDPASRAEIQAKLVAVGRQYNTLQKKLDH 871
BLAST of Dystonin vs. Ensembl Cavefish
Match: DST (dystonin [Source:HGNC Symbol;Acc:HGNC:1090]) HSP 1 Score: 769.615 bits (1986), Expect = 0.000e+0 Identity = 514/1639 (31.36%), Postives = 882/1639 (53.81%), Query Frame = 3 Query: 14346 EKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKL-QIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWND-LKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELIN-QLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEAT---QRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQD-SKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTP--PL----IPIFDRS----KRMETNQGISKIQEPLF--VNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF 19163 E ++ + E+ +R++ + + + G+ K+ E+ D + L+ E+K++ + D + ++L+E K +++ K++++ + ++ ++ ++LK+ V + ++ + ++ + QL+ LA +F +Y L WL ET+ N Q ++ + L + ++E++ L + KP +D + K+G L ++ + VQG+ I + K Y +K +K RA L++ I +T+ ++K+D LE I +R+ SV EK+ E++ + DL+KLQ + L Q G E + R DKD L+ + ++ L+++ + + +Q+ E + K+++++ LA +FW D LI +TI T + +L V+ +++ +E R EID ++++ + G +L+ P++ P ++++ +E+ +E + + ++++ ++ + ++ + +W + ++L + P+ T+ V QI++ KE K + ++E +N Q G L K + + + + W L + L RQH+L+ LL+LG+F A+DE + W+ TE+ L K GD ++E+ LA+H +++ D+ +++V + + +++++ SS G EA +LE L W + E + L+ AL +A F+G+ +++ + + + +L K GGLPDTA+EQL +++ T + + ++ + + E D+ L KW+ V+ RK +LE+A FH + FINWLT E+ L P S I+ TIL Q++ H+ ++ SHR++++ LDK THLKY SQK D+VLI+NL+ S+ RWEKVV RS ER R LD K AK+F + L++ + + L+ + I P KI+ Q+ +HKEF LG + YD+T R G L+DK ++D ++K+D+++ L+ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ + GD++ V L++ H + +K+L R ++ + A L+ + +DSS+++ Q+ EL + W V L+ K+ RLE+A QA EF + L E+ +++E LR P++E E + ++I H F K L + + G IL +P++ ++KH+ IIK+++ ++ +W+ Q L L + LL+ LL WL AE TL + L + E K +EH+ F+ +MT KQ D D++ K+K PL IP+ ++ KR T +P NP++N L SKW+QVW + L+RR++L D ++ L+E++ NF+F+ WR+RYM WMNH KSRVMDFFRR D D DG+VTR+EFI+GI+ SKF T+R+EM VADIFD++ G+IDY +F+AAL P+++ Y KP + + I DEV +Q++KC C +++ Q G KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR AKGRTN ELREK P+GT MA F Sbjct: 29 EGLDKLVTEDNERYRSATDAIAQHVDHTGAAILKSLQFEQAADTELAWLTEAERKLSSLGDIKLEPEQTTAQLQEQKSFSMDIM----RHKDAVDDIVKTGDAIMSSKDKAEKQALKAKVQSLLEKYSAVSQLNSERCLQLERTHSLACQFWETYEELWPWLQETQANFTQLPHLAIEYEALRQQQEELRQLRELIAEHKPHIDKMNKTGPQLVEL-SPVQGEPIRDKYQATDKLYAQLKADVKHRAAALDEAISKSTQFHDKIDPMLESLERIVERLRQPPSISVEVEKIREQISENKAVNMDLEKLQPAYETLKQRGEEMIT--RSEGADKD----------LSAKAVQDKLDQMVFLWND---IQALLEEREAKLLDVMDLAEKFWCDHCALI------VTIKDTQDLLRELEEPGVDPSVVKQQQESVESYREEIDGLQEELNVVQNLGTELMTACGEPDK-PVIKKSLDEVNVAWETLNKTWKERVERLEEAMQAAVQFQDGLQGMFDWVDIMESKLDSMSPVGTDLETVKQQIKELKEFKGEAYQLQIEMERLNHQAGLLLKKVLEEGDRVAIQEPINELKMLWDGLDEKLINRQHKLEGALLALGQFQHALDELLAWLTHTEDLLNEQKKNSGDPKAIEIELAKHHVLQNDVLAHKSTVEAVNKAGSDLME---SSAGEEACGLQSKLENLNLRWRGILEKTEQRRQLLDSALLQAQGFHGEIEDMQQWLKDTERQLLASKAVGGLPDTAREQLNAHLELCGTVEVKEELYQNLLHRGQQLIALTPEGQDSTTEQDLRNLKDKWECVQTKVAERKVKLEEAFAMATDFHNSLQDFINWLTQAEQTLTMVSPASLILETILFQIDEHKVFVTEVNSHRDQIIELDKTGTHLKYFSQKQDVVLIKNLLLSVQSRWEKVVQRSVERGRLLDDARKRAKQFHESWTKLMEWLEESERALDSELEIANDPDKIKLQLAQHKEFQKALGGKHSVYDTTGRTGRALKDKTSLKDDNQKLDDMLCELRDKWDTVCGKSVERQNKLEEALLFSGQFTDALQALIDWLYKVEPQLAED-QPVHGDIDLVLNLIDSHKVFQKELGKRTGSVQALKRSARDLVENTHDDSSWVKVQMQELSTRWETVCALSVSKQTRLEQALCQAEEFHSTVHILLEWLAEAEQSLRFHGSLPDDE--EALRSLIEQHKEFMKKLEEKRVALGKAISMGEAILAICHPDSITTVKHWNTIIKARFEEVTAWARQHDQRLSTAFTELLATQELLESLLSWLQWAETTLTEKDKEPLPQEIEEVKALISEHQTFMEEMTRKQPDVDKVTKTHKRKATAEPLVQSQIPVLEKGRTCRKRSPTQNMYPATAQPQIETKNPRVNLLVSKWQQVWLLALDRRRKLNDALDRLEELKEFANFDFDVWRKRYMRWMNHKKSRVMDFFRRIDKDQDGKVTRQEFIEGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAY--KPLTDADKIEDEVTRQVAKCKCPKRFQVEQIGANKYRFYLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------AKGRTNVELREKFILPEGTTQVMASF 1610 HSP 2 Score: 88.9669 bits (219), Expect = 1.812e-16 Identity = 253/1315 (19.24%), Postives = 540/1315 (41.06%), Query Frame = 3 Query: 12987 EELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVD---IKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFED----TLYGFESAMKDLKLNIVDPYQTRDIWEE-----SLNL-VKEVKSHEETLKNLDQVGEDLKQISSEND----SAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRE------NDSLTGQVGE------RNMEILENETNSVEKL---VCQARNDLDKL---KSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFE---QKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKE-SINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLD-KLQIFVDKLQIGIE--NCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEE--LKRNFEAVRSSCEQQITN-------IDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQ-VNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEIL----------VKKWDTV 16745 ++++D N+ S ++ + ++ E V +R I HVD ++K +F+ + + ++ R L + + +E ++ +QL + + + + ++D++ K G ++ + + +K L+ ++ L KY + L + + +R L+ F + YE WL ++ ANF P + AIE E Q+ + L+ + E I + K I+K++ + V + + + + D++ K + + + L + + F D L E ++ L+ + I E+ ++N+ +++++ ETLK Q GE++ S D + A+ K++ + +++I ++ + + + +AE+F + L + + L+RE + S+ Q E ++ L+ E N V+ L + A + DK KS+D + E + + E +R +E + + + I E LD V ++ E Q+I E+ + Y + +I+ L N Q + + + ++ Q P ++LK L +D + L ++Q +L+ A+ +F + + L WL TE+ + + K N+ DP + + L N K ++ + K+G L + + + + +E+ R+ I E + R L+ +L + +++ L++ ++ S P+ E+L E+ ++ K +++ + L G + +P +++ + D L + + +Q++ E K K+ ++A +F N L +D + +T T+ V+ ++E + +ID H+ + +++ Q+IE Q ++ +K +V+S E+ + +D + + E KL EW +E L + + + Q+ + KE + + KH + + G L + NQ ++ L + D W + +RQ++L+ LL G+F A+ I+W+ E L + HGDI+ + + HK+ + ++ SV ++R A +++ E+ ++++L WE + + +K LE AL +A F+ + ++ L + +F G LPD +E L+ ++ ++ F K ++ ++GKAI + IL VK W+T+ Sbjct: 6 QKVLDTLNEVSSALLELVPWRAREGLDKLVTEDNERYRSATDAIAQHVDHTGAAILKSLQFEQAADTELAWLTEAERKLSSLGDIKLEPEQTTAQLQEQKSFSMDIMRHKDAVDDIVKTGDAIMSSKDKAEKQALKAKVQSLLEKYSAVSQLNSERCLQLERTHSLACQFWETYEELWPWL---QETQANFTQLPHL-AIEYEALRQQQEELRQ----LRELIAEHKPHIDKMNKTGPQLVEL-SPVQGEPIRDKYQATDKLYAQLKADVKHRAAALDEAISKSTQFHDKIDPMLESLERIVERLRQPPSISVEVEKIREQISENKAVNMDLEKLQPAYETLK---QRGEEMITRSEGADKDLSAKAVQDKLDQMVFLWNDIQALLEEREAKLLDVMDLAEKFWCDHCALIVTIKDTQDLLRELEEPGVDPSVVKQQQESVESYREEIDGLQEELNVVQNLGTELMTACGEPDKPVIKKSLDEVNVAWETLNKTWKERVERLEEAMQAAVQFQDGLQGMFDWVDIMESKLDSMSPVGTDLETVKQQIKELKEFKGEAY----QLQIEMERL----NHQAGLLLKKVLEEGDRVAIQEPINELKMLWDGLD----------EKLINRQHKLEGALLALGQFQHALDELLAWLTHTEDLLNEQKKNSGDPKAIEIELAKHHVLQNDVLAHKSTVEAVNKAGSDLMESSAGEEACGLQSKLENLNLRWRGILEKTEQRRQLLDSALLQAQGFHGEIEDMQQWLKDTERQLLASKAVGGLPDTAREQLNAHLELCGTVEVKEELYQNLLHRGQQLIALTPEGQDSTTEQD---------------------LRNLKDKWECVQTKVAERKVKLEEAFAMATDFHNSL---QDFINWLTQAEQTLTM-------VSPASLILETILFQIDEHKVFVTEVNSHRDQIIELDKTGTHLKYFSQKQDVVLIKNLLLSVQSRWEKVVQRSVERGRLLDDARKRAKQFHESWTKLMEWLEESERALDSELEIANDPDKIKLQLAQHKEFQKALGGKHSVYDTTGRTGRALKDKTSLKDDNQKLDDMLCELRDKWDTVCGKSVERQNKLEEALLFSGQFTDALQALIDWLYKVEPQLAEDQPVHGDIDLVLNLIDSHKVFQKELGKRTGSVQALKRSARDLV-ENTHDDSSWVKVQMQELSTRWETVCALSVSKQTRLEQALCQAEEFHST---VHILLEWLAEAEQSLRFHGSLPDD-EEALRSLIEQHKEFMK--------------KLEEKRVALGKAISMGEAILAICHPDSITTVKHWNTI 1240
BLAST of Dystonin vs. Ensembl Cavefish
Match: MACF1 (microtubule actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:13664]) HSP 1 Score: 765.377 bits (1975), Expect = 0.000e+0 Identity = 643/2524 (25.48%), Postives = 1216/2524 (48.18%), Query Frame = 3 Query: 12240 AEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNR-------YQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLA------AINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIG--------------AFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFED----TLYGFESAMKDLKLNIVDPYQTRDIWEE---SLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDS-LTGQVGERNMEILENETNSVEK-LVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIE-LINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXX-XXXXXXXXXXXQSIGKAI---EIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPI-QDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFV------NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF-----KFKPAT---------------------LPIPTKKPTT-------------------AKIPSPRVSQPLSSP-RIHQP----VSSPRIPQPV-TSPRIS------QNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQAS 19454 A+ L+ E+ Q LE +++ Q ++ ++P + + L + Q P +++VN+ + ++ + Q L S+ + + E +S + +R +L +++D+ D+DSL Q + + L+ L++E+E + + D LA A+N + + + Q L L + E + +F ++ E +L + N +G A ++VD ++ +++ + +G + + +E ++++ ++ L + + + H KF +LE L ++ + + ++ PS EY K+Q+ +LL L R+++++ + G + + + ++Q +L L ++ +LL A + + + L+ F + EP WL E+ L++ + T + ++ ++I +K LQ + S + L+ + + + + + D + L +R + H + + + LL L LF + L + L V YQ + E+ +L+L +E+ S ++T+ + G+ L + ++ + I K++ + + + E++ + K L E ++ ++ RF A+ ++ L S+ A + +S T +R E+ + S EK LV N++ + E ++ + + +R+++ +T++ + +A IQ Q + ++ E + Q+ ++ ID K++++ +N + ++ ++LK D + + E+ ++ + L++A L F +Y L+ WL ETE + Q +D + L + + +++ L S + KP +D I+K G L+++ + +G + +A++RY IKE +K RA L++ + + ++K+D LE R+ + EK+ E+L +LDKL L CS + + ++ + + +++ + + +G K+ ++L LA +FW D+ + T+ + +++L V+ + + E ++ E D +++ + G LI E P+V++ +E+ +E + + +++ ++ + + ++ + ++ +L + + T+ V QI++ K+ K ++ + D+E L +Q L K + ++ + L + W L + + RQH+L+ LL+LG+F A+ E W+ T +L + D ++E+ LA+H ++R D+ +A+V + +E++ SS G EA+ +L++L +SW+ L + + LE AL++A F+G+ +E + + S+L K +GGLP+TA+EQL++ M++ + + + + + + + + + G + ++ +L KW ++ + R+++LE+A+ F + INWLT E+ LN +P S I+ T+L Q++ H+ ++ +HRE++L L+K + L++ S K D+VLI+NL+ S+ RW+K+V RS +R R+LD K AK+F + R L D + L+ + I P KI+ Q+TKHKEF LG YD+T R G +RDKA + D++K+D ++ ++ KW ++C KS+ER+ L +ALL SG + +A+ L+ WL +EP+L++ + GD++ V L++ H +K+L R ++ + A LM +D+++++ QL EL + W+ V L+ K+ RL++A QA EF L E+ S++E LR + PEE E + ++ H F + + + +N G IL +P+ +IKH+I II++++ ++L+W++Q L+ L L LL++LL WL AE TL+ ++ L + + K +EH+ F+ +MT KQ D D++ K+K P P ++R T + Q+ NP++ QL S+W+QVW + L+R+++L D ++ L+E++ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+++EM VADIFD++ G+IDY +F+AAL P+++ Y +P + + I DEV +Q+++C C+ +++ Q G+ KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCRV C C A+GRTN ELREK P+G +A F + KP++ +P PTT +K P+P Q S P H P S+ ++ +P S R S P+++ +S + RTP + P + SR +R +S++GS AS Sbjct: 2895 AKHQLEVQEALGPQACSNKSLE-RLRSQQELLNSLQPQVVYLRDLAQGLVQDMPQAGGDNGDGGQQLVNQACDTEREFGEVTEKIEQCCTSLESRLQGVGEVQSSVRDVFSRLADLDDELDSLSPVGRDVDSLASQAEAVKSFL-------GRLATLRTELEGHGGECTTMLRREGSSPDLLALRRETEALNRQAGKLAERGQGRLAL----IEAAEERVREFYARLTELQGLLDLGEDGVNAQGVVGSEVEVIKQQLQEFKAVEREQVDSIQPKVQHVNAVGQGLIQSAAKHTDTQALEHDLETTNLRWNSLNKRLQEALLHCG-------KFQDALEPLLSWLSDTEELIANQKPPSAEYRVVKAQIQEQKLLQRLLDDRRATVEMIRVEGERIASTAETQDRDKIQKQLQSLGERWTDLLEKASSRQKQLEELQVLALQFHETVEPLGEWLSATERRLSSAEPMGTQTS-KITQQISRHKALQEEVLSRGAEVDHLETLGQSLSPL---SCTADR----DWLKERVGAMRSGHTDLRDWCARRETLLEQALANAQLFGEEEVEVLNWLAEVAQRLAEVSVQSYQPELLAEQHKHTLSLNEEIVSRKKTVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKSRYAEMTAGSSKALRTLEQALQLSTRFASAHEDINQWLDSVEAELNNMESDTTPAYQDRQKEL---KCVSAEKRLVLDTINEVGSALLDLVPWRAREGLDRLVADANQRYRQADETITQRVQLV-----QAAIQR---SQQVLLMLCLEPDVTVAQLQVQRAFN------IDIIR-------HKDTVDQLLNTREDILESCSEQQREALKVKTDSLSARYEAVSQNHAERFSALEQAQVLVARFWETYEELEPWLGETETLISQLPPPAIDTEALRQQQDQMRLLRESIAEHKPHIDKILKIGPQLAELSAQ-EGSTVRQRYSEAERRYLAIKEEVKNRAASLDEAFSQSAQFHDKMDPLLETLEGAVQRLRQPPPVAAEVEKIREQLAEHRAAGLELDKLLPSFSAL------CSRGEELITRAPHDDPAAQAVRSRLLRLRSLWDEIRQRAEEREG----------KLQDVLDLAGKFWADMAALLS-----TLRDSQDIVKELEDPGVDPSLIKQQIEAAEAIKAETDGLREELEIVRTLGADLIFACGE-TEKPEVKKTIDEMNAAWEGLNRTWRERMEKLEEAMTASVQYQDALQGMFDYLDNAVIKLCEMQTIGTDLSTVKQQIEELKQYKVEVYQQQIDMEKLCHQGELLLKKVTDQTDRDMIQEPLTELRHLWDNLGEKITLRQHKLEGALLALGQFQHALSELQSWLSHTHATLDTQRPVSSDPKAIEIELAKHHVLRNDVLSHRATVETVNSAGSELLD---SSPGDEASHLRDQLDELNRSWDSLLLKTKERQKLLEAALQQAEGFHGELEEFLQWLRRTESQLSAAKPTGGLPETAREQLQQHMELQSQLSQRGEQYHRLLDQGESMLLARGGEEAGPGTTQTQQNLALLQNKWASLNTKMDDRRAKLEEAVSLATGFQSSLQDTINWLTQAEQTLNMAQPPSLILDTVLFQIDEHKVFVNEVNTHREQVLALEKAGSQLRFASLKQDVVLIKNLLLSVQARWDKLVQRSLDRGRHLDEARKRAKQFHEAWRKLTDWLEEAESRLDSELEISNEPDKIKVQLTKHKEFQKALGSKQPVYDTTVRSGRAMRDKATLPADTEKLDHLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFAEALQALVDWLYRVEPQLAED-QPVHGDLDLVSNLMDSHKAFQKELGKRTSSVQALKRSARELMDTGRDDTAWVKVQLQELSNRWDTVCTLSVSKQTRLQQALKQAEEFRTAVQMLLEWLSEAEQTLRFRGVLPEES--ETLQELLHTHRDFMQTVEEKRVDVNKAAGMGEGILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHEQRLETALTELLNNAALLEELLSWLQWAETTLVQRDTEPLPQDIPQLKTLMSEHQMFMEEMTRKQPDVDKVTKTYKRK--PAEPPSSLAERRGTRKQQQSQQQQQHAVQVTGGNPRLTQLCSRWQQVWLLALDRQRKLHDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTSKLEMMAVADIFDRDGDGYIDYYEFVAALHPNKDAY--RPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVTVTPGYFC-CR----------ARGRTNLELREKFILPEGASQGLAAFRSRGRRSKPSSRTASPTRSSSSASHSAQSCASVPSAPATPTTSSRSSQSHSRGYAKPWLAHSKTPTPTKCQ--SGPEHCHTPGHEGGSTSKLKRPTFHSSRGSLTGENGGATPAAKPGRS-DNKRTPSSASGPASRAGSRAGSRASSRRGSDAS 5320 HSP 2 Score: 233.802 bits (595), Expect = 4.327e-60 Identity = 116/256 (45.31%), Postives = 176/256 (68.75%), Query Frame = 3 Query: 405 DERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI--YQFRNQYADLYANLNSALE 1166 DERD +QK+TF W+N HL+K+ K + D++ DLRDG L++LLEVLS +L + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ +I S +S DL+ K+ LL W+++A E YP + NFS+SW +G+ F AL+H+ RPDLID++ +++ S ++NLE AF A+ LGV ++++ EDV DEKS++TYV+S+++ PK + E I ++ ++A+ + +S L+ Sbjct: 23 DERDRVQKKTFTKWVNKHLIKVRKHITDLYEDLRDGHNLISLLEVLSGVQLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISEIYVSGESGDLTAKEKLLLWTQQATEGYPGLRCSNFSSSWSNGRMFNALLHRYRPDLIDMEVVARQSNRENLEQAFEIAES-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKIPEGGEGITPHEVDQRWAEYQSRFSSLLQ 277 HSP 3 Score: 109.383 bits (272), Expect = 1.849e-22 Identity = 150/791 (18.96%), Postives = 336/791 (42.48%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQ--MDMDFHQSKND----LKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTPEDFCNLEPVHRQKIVEILNQDANRLILDLK-CANIDENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLI-----LFVKNGMSETVG-LKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEA------AQD----TISSVVGNLKDVPTNLDQLISAVTTSRQNQKDVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFESKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYE 4118 W++E ++ + +DL + + ++ T I +V+E L+ Y+ + +F S ++ L+ ++ +L + S +S F+ + E + W+ KE++++ + W + + ++ K+E+F +EL+ ++ + L + NH A ++ A L+++WQW+ L C++ HL+ Y QF +A E + + +L + + ++ L + E L ++ + E + +Y+ +V ++ ++++ L R+ + ++AIC K+ + GE L +NS W++ + P++CF + + +A A ++ + + LW + + ++ V L + + +WT + + P RQ+ +E L+ + D + A +E+ + C+ H+ M TV S ++R + + L ++L+ ++ S + D + + ++ + +LK + + D+ F + S +V L+ +L ++ E+L + + +++ KLK+ +V L + + + E L ++ + PA I+ L QL+ QD ++SS V ++ T L QL R + D E Q+L + R+ ++ Q++ R + + S + A+ WI + T + Q N +SK + + + EI + + ++DE K + ++ ++ YE Sbjct: 548 GWVEETQELLERAEWGSDLPSVEQHLQEHHT----IHTAVEELLHSLKEARSYEPRVSPNFRSSYSETLAKLENQYCKLLEHSSWRLRCLESLRAFVSQCTEELIWLNEKEEEELAFDWSEN-NTNMAAKREQFAETREELDEKQEVMRSLQETADQLCLVNHPAKQTLEAYSAALQTQWQWVRQLCVCVEQHLKDNTAYFQFMSDARECETYLRQLQDTIKRQYTCDRNSRLGKLEDLLQDSMEEKEQLIEYRSSVASLVGRAKTIVQLRPRSVDCIVGTTTPIRAICDYKQIEITVNK----GEECVLEDNSQRTKWKIISPTGNEAMVPSVCFTVPPPNQEAIDIASRMEQQYQNVMSLWHQLHMNMKSVVSWHYLQKDISNISSWTLDKMRSQPPAERQQALEHLDNHLSDFQTDCRESAFFTPSEVRELEREAESCH------QHAQSLLTSMETVEKDES-----MSRSYLSELQSIKSHLQEAEQRLLRGMNTSPPSGLSGDGADTAVHIAEQEKLQQDLKGLQSNIGDVSRRCVNFFEEKPTSSSVPVLRSELNLAVEKIEKLDSLSSVYLHKLKTVDVLMRSLQIAESHLKKYEGRL-SEEDIVPADTTAIQALREQLKKWYSELEDQDHVFHSLSSEVLRAREAGTQLSQL----HPDRSPELDRYQEKAQQLIE-------RWNGVRRQMETRQADLEMLGSVLQQYREGHSALIHWI---EETTEKQENTQPEQTDSKALSEQLAQQTALVAEIEQNQVKLDECQKHSKHYCTAVKDYE 1303 HSP 4 Score: 73.9442 bits (180), Expect = 7.503e-12 Identity = 269/1421 (18.93%), Postives = 582/1421 (40.96%), Query Frame = 3 Query: 13308 SSLDELNKAGSDLLINTKEPKK--SQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDT-SPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENV-SIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAM---------KDLKLNI-----VDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDL-----KQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENE--KRFKEV---LNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNF-EQKINEMSDQINNDYSELEECKIDFTN----LLSAWNEQKESINSTINDSKKLIRQAPGSDLKS-LKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAK----KRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDR--ITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKL--IEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPD---VEQAEEELKRNFEAVRSSCEQQITNI----DRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKND----IEPKHRDIELINQLGYQLTKGSHPNIKNQ-VNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQR-LEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRF----EDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQ 17393 + + +LN AGS +N K +++Q + E+N++YE L + + + +++L + + E L WL E++L SP+ + + + QE K L ++ + ++ LK + + + +EN S + + +L D + ++K++ + ++ D L F SA K+L +++ +DP ++ +++E ++ L Q E + +Q S + D A + ++ + +D+++ + + + +ERF +L + + L + SL+ Q + ET + + Q + L + + + +++ V + ++ +E KR + V LN + ++A S A + Q E L ++ +QK E N+ E + LL +Q+ S + + L+ P D +S L+S + +++ E + L +Q ++ E + A+++ + L W+ + E+ + + +LDP L +A Q+ + L + ++PLL+ + + L + Q + + D K +R +++ E + R LE+L E E +LE + + + ++ P K E L E+L L +++ L G+ P N ++ + + F E KI L+S+ + + + S + ++ L ++D+ ++ ++ L +++ K L + LR E++ H G + + +PD + + E L R + + ++ I +R + +L E++ LD VN + G + +E + Q+Q+ K ++ + I+PK ++ +N +G L + + + Q + L N W + L +R LQ LL G+F A++ + W+ TE + N K + ++ + + K+++ ++ +A+V +M R E I + + Q+ L+ L + W +L E A ++ +LE+ AL F+ + + + + +L + G +Q+ R + +++ +S S + ++ + + +++ R++ LE+A+ + F + + +NWL + L + S + EQ + +L +I S ++ + K L + +++LI+ + I R+ ++ + SS+ R L+ + + RF ED+N+ LD + + L +E DT TP+ Q KE C L D+ +G L D P + + +D +V + +++ Sbjct: 2266 TGVSQLNGAGSSSSVNGIHTCKDLTEIQVAVAEVNSRYEQLGKNLQDRQGKQQASLELRQKARQDTETLLQWLGPREQSLTQGQAGSPSRPEV-VRAQAQENKALLSELAEHSGKVEDLKKTLKQ---LITENQDSPEAETWKQQLTDIDTRWEKANTTAAQRQT-----------ELETCADRLGSFASAANQLGPWLREKELMMSVLGPLSIDPNMLNTQKQQVQFMLREFETRRPQFHQLTQAAEGILSPAGEQGSGDKDLAEVQQELAAITKQWDDLTSRLSGRSGKIDQAQGTSERFQTLLRELSMSIADLGERLDAQASLSVQPEALRRRL--QETGEIRAELEQRKGQLAQAEQLCTELSTI--VAEPYLRDELQKRLESVSSPLNSLEERAADGLSQLQSALSSTQQFQQMFEELRSWLDQKAGERIGGANDPLPCWPEALQTLLSQQEELLRGVAQQRGSYDLIQAEGTSLLASLPAGDERSALQSRLSSLRQDWEGLNQRLNERQARIKETLSRAEQYRQHRDELAPWVTDCEQREAEIQ-PSLDPAALEEALQKGRQLGLDLDRRRPLLENLNSAADQLLE-----QSRTGEEEVRDEKAQLNRRVDSLSERLHGRTAQLEELGSRLKEFEEGRQAVERRLEAAKHQLEVQEALGPQACSNKSLERLRSQQELLNSLQPQVVYLRDLAQGLVQDMPQAGGDNGDGGQQLVNQA----CDTEREFGEVTEKIEQCCTSLESRL----QGVGEVQSSVRDVFSRLADLDDELDSLSP--VGRDVDSLASQAEAVKSFLGRLATLRTELEGH----------GGECTTMLRREGSSPDLLALRRETEALNRQAGKLAERGQGRLALIEAAEERVREFYARLTELQGLLDLGEDGVNAQ----GVVGSEVEVIKQQLQEFKAVEREQVDSIQPK---VQHVNAVGQGLIQSAAKHTDTQALEHDLETTNLRW----NSLNKR---LQEALLHCGKFQDALEPLLSWLSDTEELIANQKPPSAEYRVVKAQIQEQKLLQRLLDDRRATV-EMIRVEGERIASTAETQDRDKIQKQLQSLGERWTDLLEKASSRQKQLEELQVLALQFHETVEPLGEWLSATERRLSSAEPMGTQTSKITQQISRHKALQEEVLSRGAEVDHLETLGQSLSPLSCTADRDWLKERVGAMRSGHTDLRDWCARRETLLEQALANAQLFGEEEVEVLNWLAEVAQRLAEVSVQSYQPELLAEQHKHTLSLNEEIVSRKKTVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKSRYAEMTAGSSKALRTLEQALQLSTRFASAHEDINQ-WLDSVEAELNNMESDT----TPAYQDRQ----KELKCVSAEKRLVLDTINEVGSALLDLVPWRAREGLDRLVADANQRYR 3617
BLAST of Dystonin vs. Ensembl Cavefish
Match: MACF1 (microtubule actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:13664]) HSP 1 Score: 761.14 bits (1964), Expect = 0.000e+0 Identity = 643/2523 (25.49%), Postives = 1218/2523 (48.28%), Query Frame = 3 Query: 12240 AEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNR-------YQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLA------AINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTV------ISGLG-------FKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFED----TLYGFESAMKDLKLNIVDPYQTRDIWEE---SLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDS-LTGQVGERNMEILENETNSVEK-LVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVN-----DKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIE-LINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXX-XXXXXXXXXXXQSIGKAI---EIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPI-QDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFV------NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPF-----KFKPAT---------------------LPIPTKKPTT-------------------AKIPSPRVSQPLSSP-RIHQP----VSSPRIPQPV-TSPRIS------QNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQAS 19454 A+ L+ E+ Q LE +++ Q ++ ++P + + L + Q P +++VN+ + ++ + Q L S+ + + E +S + +R +L +++D+ D+DSL Q + + L+ L++E+E + + D LA A+N + + + Q L L + E + +F ++ E +L + N +G+ +V+ +K+QL+E + + ++ ++ +G KH + + +++H + + + + L+ KF +LE L ++ + + ++ PS EY K+Q+ +LL L R+++++ + G + + + ++Q +L L ++ +LL A + + + L+ F + EP WL E+ L++ + T + ++ ++I +K LQ + S + L+ + + + + + D + L +R + H + + + LL L LF + L + L V YQ + E+ +L+L +E+ S ++T+ + G+ L + ++ + I K++ + + + E++ + K L E ++ ++ RF A+ ++ L S+ A + +S T +R E+ + S EK LV N++ + E ++ + + +R+++ +T++ + +A IQ Q + ++ E + Q+ ++ ID K++++ +N + ++ ++LK D + + E+ ++ + L++A L F +Y L+ WL ETE + Q +D + L + + +++ L S + KP +D I+K G L+++ + +G + +A++RY IKE +K RA L++ + + ++K+D LE R+ + EK+ E+L +LDKL L CS + + ++ + + +++ + + +G K+ ++L LA +FW D+ + T+ + +++L V+ + + E ++ E D +++ + G LI E P+V++ +E+ +E + + +++ ++ + + ++ + ++ +L + + T+ V QI++ K+ K ++ + D+E L +Q L K + ++ + L + W L + + RQH+L+ LL+LG+F A+ E W+ T +L + D ++E+ LA+H ++R D+ +A+V + +E++ SS G EA+ +L++L +SW+ L + + LE AL++A F+G+ +E + + S+L K +GGLP+TA+EQL++ M++ + + + + + + + + + G + ++ +L KW ++ + R+++LE+A+ F + INWLT E+ LN +P S I+ T+L Q++ H+ ++ +HRE++L L+K + L++ S K D+VLI+NL+ S+ RW+K+V RS +R R+LD K AK+F + R L D + L+ + I P KI+ Q+TKHKEF LG YD+T R G +RDKA + D++K+D ++ ++ KW ++C KS+ER+ L +ALL SG + +A+ L+ WL +EP+L++ + GD++ V L++ H +K+L R ++ + A LM +D+++++ QL EL + W+ V L+ K+ RL++A QA EF L E+ S++E LR + PEE E + ++ H F + + + +N G IL +P+ +IKH+I II++++ ++L+W++Q L+ L L LL++LL WL AE TL+ ++ L + + K +EH+ F+ +MT KQ D D++ K+K P P ++R T + Q+ NP++ QL S+W+QVW + L+R+++L D ++ L+E++ NF+F+ WR++YM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ SKF T+++EM VADIFD++ G+IDY +F+AAL P+++ Y +P + + I DEV +Q+++C C+ +++ Q G+ KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR A+GRTN ELREK P+G +A F + KP++ +P PTT +K P+P Q S P H P S+ ++ +P S R S P+++ +S + RTP + P + SR +R +S++GS AS Sbjct: 3243 AKHQLEVQEALGPQACSNKSLE-RLRSQQELLNSLQPQVVYLRDLAQGLVQDMPQAGGDNGDGGQQLVNQACDTEREFGEVTEKIEQCCTSLESRLQGVGEVQSSVRDVFSRLADLDDELDSLSPVGRDVDSLASQAEAVKSFL-------GRLATLRTELEGHGGECTTMLRREGSSPDLLALRRETEALNRQAGKLAERGQGRLAL----IEAAEERVREFYARLTELQGLLDLGEDGVNAQGVVGS----EVEVIKQQLQEFKAVEREQVDSIQPKVQHVNAVGQGLIQSAAKHTDTQ--ALEHDLETTNLRWNSLNKRLQEALLHCGKFQDALEPLLSWLSDTEELIANQKPPSAEYRVVKAQIQEQKLLQRLLDDRRATVEMIRVEGERIASTAETQDRDKIQKQLQSLGERWTDLLEKASSRQKQLEELQVLALQFHETVEPLGEWLSATERRLSSAEPMGTQTS-KITQQISRHKALQEEVLSRGAEVDHLETLGQSLSPL---SCTADR----DWLKERVGAMRSGHTDLRDWCARRETLLEQALANAQLFGEEEVEVLNWLAEVAQRLAEVSVQSYQPELLAEQHKHTLSLNEEIVSRKKTVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKSRYAEMTAGSSKALRTLEQALQLSTRFASAHEDINQWLDSVEAELNNMESDTTPAYQDRQKEL---KCVSAEKRLVLDTINEVGSALLDLVPWRAREGLDRLVADANQRYRQADETITQRVQLV-----QAAIQR---SQQVLLMLCLEPDVTVAQLQVQRAFN------IDIIR-------HKDTVDQLLNTREDILESCSEQQREALKVKTDSLSARYEAVSQNHAERFSALEQAQVLVARFWETYEELEPWLGETETLISQLPPPAIDTEALRQQQDQMRLLRESIAEHKPHIDKILKIGPQLAELSAQ-EGSTVRQRYSEAERRYLAIKEEVKNRAASLDEAFSQSAQFHDKMDPLLETLEGAVQRLRQPPPVAAEVEKIREQLAEHRAAGLELDKLLPSFSAL------CSRGEELITRAPHDDPAAQAVRSRLLRLRSLWDEIRQRAEEREG----------KLQDVLDLAGKFWADMAALLS-----TLRDSQDIVKELEDPGVDPSLIKQQIEAAEAIKAETDGLREELEIVRTLGADLIFACGE-TEKPEVKKTIDEMNAAWEGLNRTWRERMEKLEEAMTASVQYQDALQGMFDYLDNAVIKLCEMQTIGTDLSTVKQQIEELKQYKVEVYQQQIDMEKLCHQGELLLKKVTDQTDRDMIQEPLTELRHLWDNLGEKITLRQHKLEGALLALGQFQHALSELQSWLSHTHATLDTQRPVSSDPKAIEIELAKHHVLRNDVLSHRATVETVNSAGSELLD---SSPGDEASHLRDQLDELNRSWDSLLLKTKERQKLLEAALQQAEGFHGELEEFLQWLRRTESQLSAAKPTGGLPETAREQLQQHMELQSQLSQRGEQYHRLLDQGESMLLARGGEEAGPGTTQTQQNLALLQNKWASLNTKMDDRRAKLEEAVSLATGFQSSLQDTINWLTQAEQTLNMAQPPSLILDTVLFQIDEHKVFVNEVNTHREQVLALEKAGSQLRFASLKQDVVLIKNLLLSVQARWDKLVQRSLDRGRHLDEARKRAKQFHEAWRKLTDWLEEAESRLDSELEISNEPDKIKVQLTKHKEFQKALGSKQPVYDTTVRSGRAMRDKATLPADTEKLDHLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFAEALQALVDWLYRVEPQLAED-QPVHGDLDLVSNLMDSHKAFQKELGKRTSSVQALKRSARELMDTGRDDTAWVKVQLQELSNRWDTVCTLSVSKQTRLQQALKQAEEFRTAVQMLLEWLSEAEQTLRFRGVLPEES--ETLQELLHTHRDFMQTVEEKRVDVNKAAGMGEGILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHEQRLETALTELLNNAALLEELLSWLQWAETTLVQRDTEPLPQDIPQLKTLMSEHQMFMEEMTRKQPDVDKVTKTYKRK--PAEPPSSLAERRGTRKQQQSQQQQQHAVQVTGGNPRLTQLCSRWQQVWLLALDRQRKLHDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTSKLEMMAVADIFDRDGDGYIDYYEFVAALHPNKDAY--RPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------ARGRTNLELREKFILPEGASQGLAAFRSRGRRSKPSSRTASPTRSSSSASHSAQSCASVPSAPATPTTSSRSSQSHSRGYAKPWLAHSKTPTPTKCQ--SGPEHCHTPGHEGGSTSKLKRPTFHSSRGSLTGENGGATPAAKPGRS-DNKRTPSSASGPASRAGSRAGSRASSRRGSDAS 5657 HSP 2 Score: 255.373 bits (651), Expect = 1.494e-66 Identity = 147/352 (41.76%), Postives = 216/352 (61.36%), Query Frame = 3 Query: 120 MSGEHFSRYSERLNISEHREKRRKLHAQQSN-SLPPKYRGVNTAPIIDIYSKSNLSVKSPRRSESHSQNRLDLNEVQLSINLLQLDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI--YQFRNQYADLYANLNSALE 1166 MS SER +SE R +++S SL P NT P D NLS R+ +S Q S+ LDP +R V+RVADERD +QK+TF W+N HL+K+ K + D++ DLRDG L++LLEVLS +L + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ +I S +S DL+ K+ LL W+++A E YP + NFS+SW +G+ F AL+H+ RPDLID++ +++ S ++NLE AF A+ LGV ++++ EDV DEKS++TYV+S+++ PK + E I ++ ++A+ + +S L+ Sbjct: 1 MSSSDEETLSERSCVSE-----RSFRSERSGGSLSPCSHATNTGPKGDTLP-WNLSRHERRKRKS-----------QDSV----LDPAERAVVRVADERDRVQKKTFTKWVNKHLIKVRKHITDLYEDLRDGHNLISLLEVLSGVQLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISEIYVSGESGDLTAKEKLLLWTQQATEGYPGLRCSNFSSSWSNGRMFNALLHRYRPDLIDMEVVARQSNRENLEQAFEIAES-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKIPEGGEGITPHEVDQRWAEYQSRFSSLLQ 330 HSP 3 Score: 97.8265 bits (242), Expect = 4.559e-19 Identity = 149/790 (18.86%), Postives = 336/790 (42.53%), Query Frame = 3 Query: 1827 NWIDEKCAIISEINFTNDLDGLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQ--MDMDFHQSKND----LKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQVLLSTM--DLVKNWTPEDFCNLEPV-HRQKIVEILNQDANRLILDLK-CANIDENEINKFHFALNQCNARFAELAHSSVFSVQMRTVSNQSSSPVKAVNRESFTSVDLQLDDLISVFTKMLQELSIKLASPXXXXXXXXXXQVCKHKEFETNLKNYEPQVNDLI-----LFVKNGMSETVG-LKVKLERMIDLWEQLWNEAHMFVIKLKSTEVFFSQLDEIDQVICEMELTLINQNESFPAGIDQIKILIAQLEA------AQD----TISSVVGNLKDVPTNLDQLISAVTTSRQNQKDVSYEDIQKLKKELKSVEYRYELLKNQIKKRLSHVNECSSQYLGLKNELKAIQAWIIGLQTTVKSQINVPNNVFESKNIESLMKKINNFQLEINKYKPEIDEINKSATYFLNLLQKYE 4118 W++E ++ + +DL + + ++ T I +V+E L+ Y+ + +F S ++ L+ ++ +L + S +S F+ + E + W+ KE++++ + W + + ++ K+E+F +EL+ ++ + L + NH A ++ A L+++WQW+ L C++ HL+ Y QF +A E + + +L + + ++ L + E L ++ + E + +Y+ +V ++ ++++ L R+ + ++AIC K+ + GE L +NS W++ + P++CF + + +A A ++ + + LW + + ++ V + D++++ F L + RQ+ +E L+ + D + A +E+ + C+ H+ M TV S ++R + + L ++L+ ++ S + D + + ++ + +LK + + D+ F + S +V L+ +L ++ E+L + + +++ KLK+ +V L + + + E L ++ + PA I+ L QL+ QD ++SS V ++ T L QL R + D E Q+L + R+ ++ Q++ R + + S + A+ WI + T + Q N +SK + + + EI + + ++DE K + ++ ++ YE Sbjct: 601 GWVEETQELLERAEWGSDLPSVEQHLQEHHT----IHTAVEELLHSLKEARSYEPRVSPNFRSSYSETLAKLENQYCKLLEHSSWRLRCLESLRAFVSQCTEELIWLNEKEEEELAFDWSEN-NTNMAAKREQFAETREELDEKQEVMRSLQETADQLCLVNHPAKQTLEAYSAALQTQWQWVRQLCVCVEQHLKDNTAYFQFMSDARECETYLRQLQDTIKRQYTCDRNSRLGKLEDLLQDSMEEKEQLIEYRSSVASLVGRAKTIVQLRPRSVDCIVGTTTPIRAICDYKQIEITVNK----GEECVLEDNSQRTKWKIISPTGNEAMVPSVCFTVPPPNQEAIDIASRMEQQYQNVMSLWHQLHMNMKSVVSWHYLQKDIIQS-----FHRLSLISERQQALEHLDNHLSDFQTDCRESAFFTPSEVRELEREAESCH------QHAQSLLTSMETVEKDES-----MSRSYLSELQSIKSHLQEAEQRLLRGMNTSPPSGLSGDGADTAVHIAEQEKLQQDLKGLQSNIGDVSRRCVNFFEEKPTSSSVPVLRSELNLAVEKIEKLDSLSSVYLHKLKTVDVLMRSLQIAESHLKKYEGRL-SEEDIVPADTTAIQALREQLKKWYSELEDQDHVFHSLSSEVLRAREAGTQLSQL----HPDRSPELDRYQEKAQQLIE-------RWNGVRRQMETRQADLEMLGSVLQQYREGHSALIHWI---EETTEKQENTQPEQTDSKALSEQLAQQTALVAEIEQNQVKLDECQKHSKHYCTAVKDYE 1350 HSP 4 Score: 75.0998 bits (183), Expect = 4.228e-12 Identity = 269/1421 (18.93%), Postives = 582/1421 (40.96%), Query Frame = 3 Query: 13308 SSLDELNKAGSDLLINTKEPKK--SQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDT-SPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENV-SIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAM---------KDLKLNI-----VDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDL-----KQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENE--KRFKEV---LNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNF-EQKINEMSDQINNDYSELEECKIDFTN----LLSAWNEQKESINSTINDSKKLIRQAPGSDLKS-LKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAK----KRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDR--ITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKL--IEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPD---VEQAEEELKRNFEAVRSSCEQQITNI----DRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKND----IEPKHRDIELINQLGYQLTKGSHPNIKNQ-VNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQR-LEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRF----EDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQ 17393 + + +LN AGS +N K +++Q + E+N++YE L + + + +++L + + E L WL E++L SP+ + + + QE K L ++ + ++ LK + + + +EN S + + +L D + ++K++ + ++ D L F SA K+L +++ +DP ++ +++E ++ L Q E + +Q S + D A + ++ + +D+++ + + + +ERF +L + + L + SL+ Q + ET + + Q + L + + + +++ V + ++ +E KR + V LN + ++A S A + Q E L ++ +QK E N+ E + LL +Q+ S + + L+ P D +S L+S + +++ E + L +Q ++ E + A+++ + L W+ + E+ + + +LDP L +A Q+ + L + ++PLL+ + + L + Q + + D K +R +++ E + R LE+L E E +LE + + + ++ P K E L E+L L +++ L G+ P N ++ + + F E KI L+S+ + + + S + ++ L ++D+ ++ ++ L +++ K L + LR E++ H G + + +PD + + E L R + + ++ I +R + +L E++ LD VN + G + +E + Q+Q+ K ++ + I+PK ++ +N +G L + + + Q + L N W + L +R LQ LL G+F A++ + W+ TE + N K + ++ + + K+++ ++ +A+V +M R E I + + Q+ L+ L + W +L E A ++ +LE+ AL F+ + + + + +L + G +Q+ R + +++ +S S + ++ + + +++ R++ LE+A+ + F + + +NWL + L + S + EQ + +L +I S ++ + K L + +++LI+ + I R+ ++ + SS+ R L+ + + RF ED+N+ LD + + L +E DT TP+ Q KE C L D+ +G L D P + + +D +V + +++ Sbjct: 2614 TGVSQLNGAGSSSSVNGIHTCKDLTEIQVAVAEVNSRYEQLGKNLQDRQGKQQASLELRQKARQDTETLLQWLGPREQSLTQGQAGSPSRPEV-VRAQAQENKALLSELAEHSGKVEDLKKTLKQ---LITENQDSPEAETWKQQLTDIDTRWEKANTTAAQRQT-----------ELETCADRLGSFASAANQLGPWLREKELMMSVLGPLSIDPNMLNTQKQQVQFMLREFETRRPQFHQLTQAAEGILSPAGEQGSGDKDLAEVQQELAAITKQWDDLTSRLSGRSGKIDQAQGTSERFQTLLRELSMSIADLGERLDAQASLSVQPEALRRRL--QETGEIRAELEQRKGQLAQAEQLCTELSTI--VAEPYLRDELQKRLESVSSPLNSLEERAADGLSQLQSALSSTQQFQQMFEELRSWLDQKAGERIGGANDPLPCWPEALQTLLSQQEELLRGVAQQRGSYDLIQAEGTSLLASLPAGDERSALQSRLSSLRQDWEGLNQRLNERQARIKETLSRAEQYRQHRDELAPWVTDCEQREAEIQ-PSLDPAALEEALQKGRQLGLDLDRRRPLLENLNSAADQLLE-----QSRTGEEEVRDEKAQLNRRVDSLSERLHGRTAQLEELGSRLKEFEEGRQAVERRLEAAKHQLEVQEALGPQACSNKSLERLRSQQELLNSLQPQVVYLRDLAQGLVQDMPQAGGDNGDGGQQLVNQA----CDTEREFGEVTEKIEQCCTSLESRL----QGVGEVQSSVRDVFSRLADLDDELDSLSP--VGRDVDSLASQAEAVKSFLGRLATLRTELEGH----------GGECTTMLRREGSSPDLLALRRETEALNRQAGKLAERGQGRLALIEAAEERVREFYARLTELQGLLDLGEDGVNAQ----GVVGSEVEVIKQQLQEFKAVEREQVDSIQPK---VQHVNAVGQGLIQSAAKHTDTQALEHDLETTNLRW----NSLNKR---LQEALLHCGKFQDALEPLLSWLSDTEELIANQKPPSAEYRVVKAQIQEQKLLQRLLDDRRATV-EMIRVEGERIASTAETQDRDKIQKQLQSLGERWTDLLEKASSRQKQLEELQVLALQFHETVEPLGEWLSATERRLSSAEPMGTQTSKITQQISRHKALQEEVLSRGAEVDHLETLGQSLSPLSCTADRDWLKERVGAMRSGHTDLRDWCARRETLLEQALANAQLFGEEEVEVLNWLAEVAQRLAEVSVQSYQPELLAEQHKHTLSLNEEIVSRKKTVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKSRYAEMTAGSSKALRTLEQALQLSTRFASAHEDINQ-WLDSVEAELNNMESDT----TPAYQDRQ----KELKCVSAEKRLVLDTINEVGSALLDLVPWRAREGLDRLVADANQRYR 3965
BLAST of Dystonin vs. Ensembl Cavefish
Match: plecb (plectin b [Source:ZFIN;Acc:ZDB-GENE-100917-2]) HSP 1 Score: 348.591 bits (893), Expect = 7.969e-95 Identity = 258/903 (28.57%), Postives = 449/903 (49.72%), Query Frame = 3 Query: 405 DERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEE-DIEEKIYQFRNQYADLYANLNSALEELNDD---FDHNDFRIDFNQTRLENNYLTYLKQYESFCHLFD-DISKV------DRNNENQRK----FHTIST--LWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIE---CATLTNKVEE-IESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDG--YPADQHYRIIININGKIDKVKK------KFEKLSPPTLSSGVISNRQYTPIHSMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLD----------GLNKIYEKFSTTFNEIKDSVDEFKMILESENKY-----QMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFI--EGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLRE----QVLLSTMDLVKNW 2963 DERD +QK+TF W+N HL+K + V D++ DLRDG L++LLEVLS + L + RFH L+N+ LDFLR + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +SDD+S K+ LL WS++ +E Y + +NF+TSW+DGK F A+IH+ P L+D+ + + + QNLE AFN A+KELGV ++++PEDV DEKS++TYV+SL++ P+E ++ + ++ + Y + L+ + F+ F F + + K+ E D D SK+ Q K +H I W + E+ +L E ++++R ++I + +E C N +E ++S IR +S + +Y A + ++L ++ I + VQ LK DG A+Q YR + ++ ++ ++ K + PP SS +P EL D+V W++E I + +DL GL++ E F + + DE ++ S++ Y ++D+ + + N K++ N ++ A F++ + + + W+ KE++++++ W D + ++ K+E + L+ ELE+RE +NE A G L H ++ A L+++W WIL L C++ HL+ Y QFF + EAD + ++ + + ++ E L ++ D E + ++K + + ++S+ L R + + + V+A+C DF + +GE L NNS W+V N P++CFL+ ++ +A ++ LD+ + LW + + ++ Q L+ + ++++W Sbjct: 9 DERDRVQKKTFTKWVNKHLIKAQRHVSDLYEDLRDGHNLISLLEVLSGETLPREKGRMRFHKLQNVQIALDFLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVNGQSDDMSAKEKLLLWSQRMVEGYQGMRCDNFTTSWRDGKLFNAVIHRHEPRLVDMSKVYRQTNLQNLEQAFNVAEKELGVTRLLDPEDVDVPHPDEKSIITYVSSLYDAMPRETVSGGVRVSELELRWQEYYELVTILLQWIRHHVIIFEERKFPASFEEIEILWRQFLKFKETELPAKEADKDRSKLVYQSFESAVQAGQIKVPPGYHPIDVEKEWGRLHVAILERERLLRTEFERLERLQRIVSKVQMESGVCEEQLNHLETLLQSDIRLLS-------AGKPAQYTAEVGRDLDKADDMIRLLFNDVQILK-DGRHLQAEQMYRRVYRLHERLVNLRSDYNLRMKSAVVVPPLTSSP-------SPRARPEL-DDVTLRYAQDLLAWVEENQRRIETAEWGSDLPTVESQLGSHRGLHQTVEDFKSKIERAR--ADENQLSPMSKSTYREYLARLDLQYAKLLNSSKSRLR----NLDQLHA-------FVNAATKELIWLNDKEEEEVNFDWSD-RNTNMTAKKENYSGLMRELELREKKVNEIQATGDRLIREGHPGKKTVEAFTAGLQTQWSWILQLCCCIEAHLKENTAYYQFFADVKEADEKMKKMQDTMKKKYTCDRSTTSTRLEDLVKDALDEKEQLNEFKTQLAGLNKRARSIIQLKPRNPTNPIKGKQPVQAVC------DFKQMEITVHKGEECALLNNSQPSNWKVLNRSGAEAIVPSVCFLVPPVNKEAVESVSNLDAGLQQMTTLWQRLHIDMKSLLSWQYLMKDIQIIRSW 875
BLAST of Dystonin vs. Ensembl Cavefish
Match: pleca (plectin a [Source:ZFIN;Acc:ZDB-GENE-030131-8984]) HSP 1 Score: 279.256 bits (713), Expect = 7.358e-74 Identity = 225/886 (25.40%), Postives = 419/886 (47.29%), Query Frame = 3 Query: 456 HLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKI----YQFR-NQYADLYANLNSALEELNDDFDHNDFRIDFNQTRLENNYLTYLKQYESFC-----------HLFDDISKVDRNNENQ--RKFHT--ISTLWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMN-----EYLASISKELCDCENQINNMIISVQELKRDG--YPADQHYRIIININGKIDKVKKKFEKLSPPTLSSGVISNR------------QYTPIHSMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLDGLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFK-SFLEFLHKSNESIA--WIKTKEDQQ----IHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLRE----QVLLSTMDLVKNW 2963 HL+K + + D++ DLRDG L++LLEVLS + L + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +SDD++ K+ LL W+++ +E Y + +NF+TSW+DGK F +IHK RP LID+ + + + +NLE AF A+++LGV ++++PEDV DEKS++TYV+SL+++ P+ D+++ + + R +Y +L L + F+ F + + +E + +LK E+ H++ + + + +H + W + E+ +L E ++++R ++I + +E ++ ++ES +L+T + + ++ A I +L EN I + VQ+LK DG A+Q YR + ++ ++ ++ ++ L SGV + Q +P D V + W+DE I + +DL + E++ HQS D ++K + + +++ K ++ E+L K + + T+ + Q I + FD + E+ E+ D+L ++E H A + ++ +A L+++W W+L L C++THL+ Y QFF + EA+ + ++ + ++ + + E L ++ D E + ++K ++ + ++++ L R + + ++ V+A+C K+ R G+ L NNS W+V ++ P+ICF++ + +A ++ LDS L LW K + ++ Q L+ + + +W Sbjct: 1 HLIKAQRHITDLYEDLRDGHNLISLLEVLSGETLPREKGRMRFHKLQNVQIALDFLKHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVNGQSDDMTAKEKLLLWAQRMVEGYQGLRCDNFTTSWRDGKLFNGIIHKHRPHLIDMSKVYRQTNLENLEQAFCVAERDLGVTRLLDPEDVDVPHPDEKSIITYVSSLYDVMPRVPDVQDGVQANELELRWQEYYELVTMLLQWIRHHVIVFEEKKFPTSYEE--IEVLWRQFLKFKETELPAKEADKNRSKHIYKAFEGAVQAGQIKVPPGYHPLDVEKEWGRLHVAILERERLLRTEFERLERLQRIVSKVQMESGVCEEQLNQVES--------LLQTDVRALGSGKPVQHAAEIEADLDKAENMIRFLFNDVQQLK-DGRHLQAEQMYRRVYRLHERLVNLRSEYN----LRLKSGVTITQVPVTQISMSQTLQQSPQRVRPELDEVTLRYIQDLLGWVDENQRRIDGATWGSDLPSV---------------------------ESQLGSHRGLHQSIEDFRSKIDRARADENQLTPVSKGAYREYLGKLDLQYGKLLVSTELETQNIIKIMFTGFDARTGTAGEENEQCSGHGDKL-LKE----------------GHPAKSTVEAFMAALQTQWSWMLQLCCCIETHLKENTAYFQFFSDVKEAEERMRKMQESMKKKYVCDRSITVTRLEDLLQDAVDEKEQLTEFKTHLDGLNRRAKTIIQLKPRNPATPVKGKLPVQAVCDFKQMEITVHR----GDECALLNNSQPFKWKVRSTSGSEATVPSICFIVPPTNKEAVESTSGLDSSLQKLMILWQKLHVDMKSLLSWQYLMRDIQFINSW 823
BLAST of Dystonin vs. Ensembl Sea Lamprey
Match: MACF1 (microtubule actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:13664]) HSP 1 Score: 817.765 bits (2111), Expect = 0.000e+0 Identity = 619/2390 (25.90%), Postives = 1188/2390 (49.71%), Query Frame = 3 Query: 12465 SSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAE--QKIETAEKSM------HKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAK--------------LLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSE-YQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAF------ENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSD---QINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHP---EKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVN-----STLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQ---RLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAP-IQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFV-------NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRH 19463 + + ++ L+ + + ++ + + T +L +++D ++ D+D+L+ Q+ L + I++ L NL+ E+ E K++ E M +++ L + ++ + D RQ L E ++ DF RKI N + A+ L+N + +F + +V+PL+ ++E+ +G+ + + + +E E++ ++ L + V++ + L+ KF +LE+L ++ + + ++ PS EY K+Q+ +LL L R+ S++ + K G + + P K ++ +L L ++E L + A+ + + + + +++ F + EP WL EK L+N + T AI+++++I ++K L+ D ++ + + +L + + + ++ ++ R+ E +++ L + D+V L + L + + D+ P + +E L+L +E+ S ++T+ + G++L + ++ ++ I K++ + + + EI+ S+ + L E ++ +A +F + +L+ L + + D+ VGE+ + +++ N++ K V + R LD + V + + E ++ + E+ R++ V + V +K ++ + +++ E+ D + ++ E+K+ + D + + S+L+ K ++L K+SI+ + +L + +++S + + + + ++ + QL+ A L+ +F +Y L WLVET E++ +++ + L + ++E++ L S + KP +D + K G L ++ + +G + A++ + I+E ++ RA L++ + ++++ E D+ LE + I P P EK+ E+L I +L+KLQ + L+ E A + ++ I D KL ++ S + +QS++ E + +++++L LA FW DL + E ++ + ++ + +++ + + +ID ++D+ + G LI P++ P+V+++ +E+ +++ + + ++ ++ + ++ + +W + + L P+ T+ V Q++ K+LK + + ++E ++ G + K +K + N L + + W L + RQH+++ LL+LG+F A+DE + W+ TE L K + ++E+ LA+H ++R D+ Q++V ++R +++ +SS G + T R R E L E + L D L +A F G+ + + + ++ ++L K GGLP+TAKEQL M++ + ++ QS ++ ++ L KW V N R+++LE A++T FH + FI WLT E NLN P S I+ ++L Q++ H+ L ++ +HRE+++ LDK THLKY SQK D+ LI+NL+ S+ RWE ++ + ER R+LD K AK+F + L+D + + L+ + G P +I+ + +HK+ +LG YDST R G L+++A + D +++D ++ L+ KW ++C KS+ER+ L +ALL SG + +A+ L+ WL +EP LS+ + GD+ V TL++ H + +++L R + + A L+ S+ D+S++ Q+AEL + W+ V KL+ K+ RL+ A QA F L S+ + +++E LR P++E + + +I+ H F + L ++ G IL +P++ +IK +INII++++ ++++W+ Q L+ L L LL+++L WL A+ L + L + + +EH+ F+ +M KQ + +++ + K+K +FDR++ +G + P NP+I L ++W+QVW + L R+++L D +E L+E++ +NF+F+ WR+RYM WMNH KSRVMDFFRR D D DG++TR+EFIDGI+ S+F T R+EM VADIFD++ G+IDY +F+AAL P+++ Y +P + + I DEV +Q++ C C+ +++ Q G+ KY+ FGD+++LRLVRILRS VMVR+GGGW ALDEFLVK+DPCR AKGRTN ELREK P+G +M PF+ + PS R + P + H P + PSS S + ++PR + + PG + T S AS H Sbjct: 1024 AGITERCSVLDGRLQGVNRFQGHVRELFTSLTDLDDELDTMGPTARDVDTLQCQLEHLGS-------IQEKLQNLRDEIRKAGEGCAKMQENEAGMDLQGVKREVETLKKQSGRLADRTDTRQAEL-------QETLAQVEDFHRKIQALNQQLQAAEATEDEQGPVAAELELINQQMETFQSFQKGEVEPLQVSVQEVNTLGHGLVQSAAKSVATQGLEHELEETNACWNTLNKKVAERAVQLQRALLHCGKFQDALESLLSWLADTEELIANQKPPSAEYKVVKAQIQEQKLLALLLDDRKHSIEVIRKEGQQIADSADAPDKEKILKQLSSLGRRWEALTSKADARQKQLEGILVVAQQFHETLEPLSEWLSGTEKKLSNLEPIGT-QAIKIQQQISQHKSLEEDVNARSKPLHQLLGLGQALKASSGGGEREAVQVQLEQVQARYLETAERTRRRGELLGQALAHARLFGDDEVELL-NWLAEAQDRLADMSPGDHQPDVLQAQHDEHLSLHEEIVSRKQTVDQAIKNGQNLLKQTTGDEILTIQEKLDGIKSRYAEITGSSTRALKTLEKALHLATKFHGTHRELNEWLGHAESEMATCDTRLA-VGEQ-LAAMQDRVNTLHKDVMERRLTLDTVNEVSSALLELVPWRAREGLDRLVAEDNSRYRVVSDAVARKTDELDAAVQRSQQFEQTADNELAWVAETERKLRALGDVSLEQDTTTSQLQVQKAFTIDIL----RHKDSIDQLVKTGDELKVSCSEEEKAAMESKLASLLEHYDVVSRLNTGRLSQLERAQLLSTQFWETYEELMPWLVETRESLGHLPPPSIEQETLRQQQEELRQLRESIAEHKPYVDKLKKIGPQLEEL-SLSEGPALREKYTGAERLFEAIREDVRLRALGLDEALSQSSQIKEFHDKMDVMLEGLGRIIERLRMPPPIPAEAEKIKEQLAENKNIALELEKLQPMFNLLKESGEELVGLSGGAEKELNAKAIKD--------------KLGQMLSLWEEIQSRSEERENRLLDVLDLAERFWTDLGTMLATLKETREYMQDLEELGVDPSLIKQQEEYMLANKNDIDGFQEDLEILRYLGTNLISACGEPDK-PEVKKSIDEMNSSWDRLNKCWKDRMDKLEEAMKTAMQYQDALQSMFDWVENATTEMENLPPVGTDLETVKRQMEDLKQLKTESYQQQIEMERLSHQGELMLK----RVKEEENRMVIAGPLRDLKEQWETLDTKILNRQHKMEAALLALGQFQHALDELLTWLEHTEGLLEEQKPVANEPKAIEIELAKHHVLRNDVLAHQSTVGTVQRAGQDLV---LSSSGADPTTERIRTSTKRNRKENLTETTIRREPSLTDNL-QAQGFQGEMDGLLQWLSDMENQLSDTKPVGGLPETAKEQLSTHMEMCEEYQV--KHGLYTKVLEQCQRMQNEQSGEPTLKYGIQDLEHKWKIVGNKLNERRAKLETALKTAIEFHNSLQDFIGWLTQMENNLNTLSPASLILDSVLFQIDEHKMLANEVNTHREQIIELDKTGTHLKYFSQKQDVALIKNLLLSVQTRWEHIMQSTLERGRSLDDARKRAKQFHESWTKLMDWLEGAEKGLDHELDCGNDPERIKLMLGRHKDIQKSLGAKQPIYDSTTRTGRTLKERATLVDDDQRLDNMLSELRDKWDTICGKSVERQHKLEEALLFSGQFAEALQVLIDWLYKVEPHLSED-QPVHGDVALVMTLIDAHKVFQRELGKRASSVNALKRSARDLLDSSKSDASWVRAQMAELSARWDTVCKLSLSKQARLDNALKQAEVFRTLVQSIMDVLAEAEKTLRFHGTLPDDE--DSLRLLIAQHKEFMERLEAQRSEVIRAVSMGEAILAVCHPDSASAIKQWINIIRTRFEEVMTWARQHQTRLEAALSELVSNSQLLEEMLAWLQKAQEMLAQRDQETLPEQIESLHYLISEHQGFMEEMMSKQPEMEQMTKSYKRKPSESHALFDRTRGSTRKRGGPQSTAPASPSQPLETKNPRITLLFNRWRQVWLVALERQRKLQDALERLQELKEFENFDFDVWRKRYMQWMNHKKSRVMDFFRRMDKDQDGKITRQEFIDGILSSRFPTNRLEMTAVADIFDRDGDGYIDYYEFIAALHPNKDAY--RPITDADKIEDEVTRQVAACKCTRRFQVEQIGENKYRFYLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR----------------------AKGRTNLELREKFILPEGASQSMTPFRMR-----------GKRSRPSSRTASPTRAGFAHSHGGHGHAYTPTPNSGGCATPPSSGSSNTPSTPRGSR-LRPPGYLSGKSLHTGDDSLTSDSASETH 3326
BLAST of Dystonin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002838.1 (pep scaffold:Pmarinus_7.0:GL477168:22072:87306:1 gene:ENSPMAG00000002584.1 transcript:ENSPMAT00000002838.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 253.062 bits (645), Expect = 4.879e-70 Identity = 119/236 (50.42%), Postives = 174/236 (73.73%), Query Frame = 3 Query: 390 VLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDI 1097 +L +ADERD +QK+TF W+N HLMK+ K V D++ DLRDG L++LLEVLS +KL + RFH L N+ LDFLR + IKLVNI ++D+ DGNPKLTLGL+W IIL FQ DI S +S+D++ K LL WS++ +E YP I +NF+TSW+DG+ F A+IH+ RP+LID+K ++ + ++NLE AF A++++GV ++++PEDV DEKS++TYV+SL+++ P+ ++ Sbjct: 1 LLLIADERDRVQKKTFTKWVNKHLMKVRKHVNDMYEDLRDGHNLISLLEVLSGEKLPREKGRMRFHRLHNVQIALDFLRLRQIKLVNIRSDDIADGNPKLTLGLIWTIILHFQIADIQVSGQSEDMTAKDRLLLWSQRMVEGYPGIRCDNFTTSWRDGRLFNAIIHRHRPELIDMKRVAVRANRENLEQAFTVAERDMGVTRLLDPEDVDVPSPDEKSIITYVSSLYDVIPRMPEV 236
BLAST of Dystonin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006515.1 (pep scaffold:Pmarinus_7.0:GL476558:286719:335794:-1 gene:ENSPMAG00000005865.1 transcript:ENSPMAT00000006515.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 244.588 bits (623), Expect = 3.925e-68 Identity = 175/670 (26.12%), Postives = 321/670 (47.91%), Query Frame = 3 Query: 405 DERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFEL--NPK------EEDIEEKIYQFRNQYADLYANLNSALEELNDDFDHNDFRIDFNQ-------------TRLENNYLTYLKQYESFCHLFDDISKVDRNNENQRKFHTISTLWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIE---CATLTNKV-EEIESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDG--YPADQHYRIIININGKIDKVKKKFEKLSPPTLSSGVISNRQYTPIHSM-ELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLDGLNKIYEK---FSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDAD-FKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQ 2318 DERD +QK+TF WIN HL ++ + D++ DLRDG L++LLE LS + + R H ++NI VL++L+ Q +KLVNI ED+VDGNPKLTLGL+W IIL +Q + ++ LL W+R +D P ++ NFS+SW+DG+ A++H RP L+DL+ + + A+QNLE A + A+ ELGVP++++PEDV DEKS++TYV++L N K + I + + ++Y L A+L +EE F ++ + L+ E + + + + + T+W + + +IL + KK++ ++++ ++++ CA NKV E +++ + I+ + + ++ IS+ L + E + ++ V+ L G P R + + ++ ++ + K++ +R + + D + L + W+ A + + + DLD + E+ T + S+ E + ++S ++ D+ +S + L+ ++++L +N S+ ++ FL + + W+ +E++++ + W D L K+E + L+ ELE RE + E + G L H IQ Sbjct: 1 DERDRVQKKTFTKWINSHLQQVRMNIGDLYEDLRDGQALISLLESLSGDCIIREKGRLRVHHVQNIQIVLNYLQHQQVKLVNIRKEDIVDGNPKLTLGLIWTIILHYQ---VSAGQVGGGTPGRERLLAWARLVAKDVPGLSCHNFSSSWRDGRLLCAIVHAHRPGLVDLEEVRRRGARQNLEEALSLAESELGVPRLLDPEDVDVDAPDEKSIITYVSALHNALHNHKVVSSIPDGVIRTALRHWLSEYWQLAASLRVWIEERTITLKSRTFPYSIDKLMVMQKEHALMKNSEFPKKKAELLQLEEVYKSMEEAVQACLIKTVPPPPPPPVRTVWGGLHVQVRYREVILRSNFKKLEMLQRLAQKMEVDTNTCAEGLNKVYEALQADVALIN-------SGRVPQHGEEISRCLSEIEVFVQSLYPDVRTLTDGGCSQPELLQSR-LRRLEEQVASLRAEHAKITAHAGEGARSRSRDEAQLQAASSQQDQTAAAYLQELLTWVQSNQATVDKSGYGKDLDETTALLEEQKALHQTIENFRSSLGEAQETMQSVSQGSR-YDYSKSLDKLEQQYSKL-LNGSRARLGLLENQQGFLRRCQREMLWLTQREEREVAYDWSDLNP-DLEPKKEAYALLVRELEQREPAFREVVQAGEDLVGEGHPGNPTIQ 656
BLAST of Dystonin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008111.1 (pep scaffold:Pmarinus_7.0:GL478136:8967:48859:1 gene:ENSPMAG00000007298.1 transcript:ENSPMAT00000008111.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 225.713 bits (574), Expect = 1.574e-58 Identity = 207/797 (25.97%), Postives = 376/797 (47.18%), Query Frame = 3 Query: 399 VADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKL-FTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDD----LSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIE---EKIYQF------RNQYADLYANLNSALEELNDDFDHNDFRIDFNQTRLENNYLTYLKQYESFCH-------------------LFDDISKVDRNNEN------QRKFHTISTLWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRK----ISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDGYPADQHYRIIININGKIDKVKKKFEKLSPPTLSSGVISNRQYTPIHSME--LGDNVLYSSLNKWKNWIDE-KCAIISEINFTNDLDGLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQS-----KNDLKTKFNELWINCSKIDADFKSFLE-------FLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDE--GEILNREIRDMLETIEDYKETVNRIIAISQSV 2609 +ADER+A+QK+TF W+N HL +++ R+ D++ DLRDG +L+ LLEVLS +KL R HCLEN++ L FL+ Q + L N+ + D+VDGN +L LGL+W IIL FQ +DI S +++D S K LL W + Y ++NI NF+TSW+DG AF A++HK RPDLI+ + K++A NL+ AFN A+++LG+ K+++PED+ DEKS++TYV + + K + + ++I + +Q D Y L S L E + I N + N+ +Q ++F LF SK+ NN+ + + I+ W + E E+ L L NE + ++ E+++ D + A + E + + + + P ++ TK+ +I ++ E ++ ++ +EL+ + Y + + + D V + +E L +++ R+ H +E L ++ + +W+DE K ++S+ ++ L G+ + +K + +I D K + + ++ + D ++ ++ T E + + A+ +S LE F + E W++ KE + + + + + + DEL R + +T+ G + H A+ I+ +A + W + +L K L+ QF +AD +E+ + R +G DE + LN++ +D+ E I Y+ ++ + +Q + Sbjct: 51 LADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGEKLPKPTRGKMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLILGLIWTIILRFQIQDI--SVETEDNKERRSAKDALLLWCQMKTAGYQNVNIHNFTTSWRDGLAFNAIVHKHRPDLIEFDKLKKSNAHHNLQNAFNIAEQKLGLTKLLDPEDISVDQPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLESAIETDQMIDKYETLASELLEWIE-----QTIIILNNRKFANSLTGVQQQLQAFSTYRTVEKPNKFTEKGNLEVLLFTIQSKMRANNQKVYTPREGKLVNEINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAALRETWLSENQRLVTQDNFGVDLPAVEAATKKHE----AIEADIAAYEERVQAVVDVARELEAEDYHE------VRRVCSRRDNVLRLWEYLQE------LLAARR----HRLEANLALQRVFQEMLHIVDWMDEMKVRLLSQ-DYGKHLLGVEDLLQKHALVEADITVQADRVKAVNAAAQRFSSEDDAYKPCDSHVVSERATHLEERYAELCSLAAERRSKLEESRKLWRFFWEMAELEGWVREKEP-LLSSGDVGKDLTGVLRLLGQHRAVEDELNGRSADLKQTVREGEEMADAGHFGADDIRARVAEMHVLWASLEDLAAQRKRRLQVAESLYQF-----QADADDIEVWMEDTLRIVSSDEMGHDEFSTQSLNKKHKDVTEEISSYRPVLDALHEQAQGL 813
BLAST of Dystonin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006506.1 (pep scaffold:Pmarinus_7.0:GL476558:286440:335800:-1 gene:ENSPMAG00000005865.1 transcript:ENSPMAT00000006506.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 214.157 bits (544), Expect = 3.980e-57 Identity = 108/256 (42.19%), Postives = 164/256 (64.06%), Query Frame = 3 Query: 399 VADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQ-SSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKIYQFRNQYADLYANLNSAL 1163 +ADERD +QK+TF WIN HL ++ + D++ DLRDG L++LLE LS + + R H ++NI VL++L+ Q +KLVNI ED+VDGNPKLTLGL+W IIL +Q + ++ LL W+R +D P ++ NFS+SW+DG+ A++H RP L+DL+ + + A+QNLE A + A+ ELGVP++++PEDV DEKS++TYV++L K +D + ++ N+ AD + L ++L Sbjct: 1 LADERDRVQKKTFTKWINSHLQQVRMNIGDLYEDLRDGQALISLLESLSGDCIIREKGRLRVHHVQNIQIVLNYLQHQQVKLVNIRKEDIVDGNPKLTLGLIWTIILHYQNASFAHIEGNHSSMQSRERLLAWARLVAKDVPGLSCHNFSSSWRDGRLLCAIVHAHRPGLVDLEEVRRRGARQNLEEALSLAESELGVPRLLDPEDVDVDAPDEKSIITYVSALHNALHK-QDGQSRVALDANEDADEFWRLAASL 255 HSP 2 Score: 53.5286 bits (127), Expect = 1.691e-6 Identity = 40/187 (21.39%), Postives = 82/187 (43.85%), Query Frame = 3 Query: 1791 DNVLYSSLNKWKNWIDEKCAIISEINFTNDLD----------GLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADF-KSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQ 2318 D + L + W+ A + + + DLD L++ E F ++ E +++ M + ++Y D+ +S + L+ ++++L +N S+ ++ FL + + W+ +E++++ + W D L K+E + L+ ELE RE + E + G L H IQ Sbjct: 573 DQTAAAYLQELLTWVQSNQATVDKSGYGKDLDETTALLEEQKALHQTIENFRSSLGEAQET-----MSVSQGSRY----DYSKSLDKLEQQYSKL-LNGSRARLGLLENQQGFLRRCQREMLWLTQREEREVAYDWSDLNP-DLEPKKEAYALLVRELEQREPAFREVVQAGEDLVGEGHPGNPTIQ 748
BLAST of Dystonin vs. Ensembl Yeast
Match: SAC6 (Fimbrin, actin-bundling protein; cooperates with Scp1p in organization and maintenance of the actin cytoskeleton; phosphorylated by Cdc28p/Clb2p in metaphase on T103, to regulate conformation, and modulate actin filament binding affinity and actin cable dynamics; relocalizes from the plasma membrane to the cytoplasm upon DNA replication stress; human homologs PLS3 and LCP1 implicated in spinocerebellar ataxia type 2 (SCA2) can each complement yeast null mutant [Source:SGD;Acc:S000002536]) HSP 1 Score: 80.1073 bits (196), Expect = 6.968e-15 Identity = 70/242 (28.93%), Postives = 123/242 (50.83%), Query Frame = 3 Query: 408 ERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLS---------DQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIII---LFFQFKDIVQSSKSDDLSIKQILLQWSR-KALEDYPDINIENFS-TSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQ----NLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELN 1079 ER+A R F W+N + ++ V +F+DL+DG++LL E + +++ + ISRF LEN N +D R++ LV I D+VDGN LTLGLVW ++ + K + SS D+S QI L+W++ + + + I +F + + L +++ P +D ++ + ++ N +A + A+K LG + PED+ + + ++T++ASL LN Sbjct: 411 EREA---RVFTLWLNS--LDVDPPVISLFDDLKDGLILLQAYEKVMPGAVDFKHVNKRPASGAEISRFKALENTNYAVDLGRAKGFSLVGIEGSDIVDGNKLLTLGLVWQLMRRNISITMKTL--SSSGRDMSDSQI-LKWAQDQVTKGGKNSTIRSFKDQALSNAHFLLDVLNGIAPGYVDYDLVTPGNTEEERYANARLAISIARK-LGALIWLVPEDINE--VRARLIITFIASLMTLN 641 HSP 2 Score: 60.077 bits (144), Expect = 1.080e-8 Identity = 50/192 (26.04%), Postives = 88/192 (45.83%), Query Frame = 3 Query: 573 ISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIII---------------LFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYP-DINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIE 1100 ++ F EN N V++ ++ +VN+H+ED+++G L LGL+W II L+ +D + L +QILL+W L+ + + NFS DG+ + L+++ P L + + E A+K L K + P +++G + K + +VA LF +P E I+ Sbjct: 208 LNNFQASENANIVINSAKAIGCVVVNVHSEDIIEGREHLILGLIWQIIRRGLLSKIDIKLHPELYRLLEDDETLEQFLRLPPEQILLRWFNYHLKQANWNRRVTNFSKDVSDGENYTILLNQLDPALCSKAPLQTTDLMERAEQVLQNAEK-LDCRKYLTPSSLVAG--NPKLNLAFVAHLFNTHPGLEPIQ 396
BLAST of Dystonin vs. Ensembl Nematostella
Match: EDO37706 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SF35]) HSP 1 Score: 511.916 bits (1317), Expect = 1.039e-149 Identity = 371/1344 (27.60%), Postives = 661/1344 (49.18%), Query Frame = 3 Query: 15612 EDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTN--IKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKE-DVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSE-EDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNE---------RKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQG--ISKIQEPLFV-----NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYK---------FGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTK----KPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQS--LASPRTPKVV---ASPGLQRKSRIPT---RQTSQQGSQASTRHQSRDISPETVTSTNKQMNE 19520 ++LR E+D H + + + L+E + P + V+ + +E + +++ + + + ++ + + W E+ +L + P+ TE V Q++ K ++ P +I INQLG + + + V++ L +N W L + RQ +L+ LL LG+F A E + W+ T+++L K GD+ +E+ LA+HK+++ D+ + SV + R A+ +++ + S E ++++L+ +W+ + + + ELE ALK++ F +E+ ++E L+ + GG P+ A +QL + D + +E + + + +++ ++ L W+ V + A +LE+A+ + WLT + ++ S I+ + Q E ++ LK DI +HR+ + +A + + K D V I +MS + RW+++++ SS R R+LD Y+ + +F L+ + + E L+ + IG P+ +R Q+ KHKEF LG + D+T ++G QL D++ +D+ I+ + +L+ +W ++C S+ER++ L +ALL +G ++DA+ +LL WL A+EP LS + GD TVQ L++ H +++L R+ + + A++ +++ E+ + +E++LA+L+ W+ V ++N K+ RLE A A EF+ + + E LR+ + P E E I + H +FH L E+ + + G IL +P A I+ ++ +K +W ++ WS QR + L++ L +L E R I + L E + + E + L E EH+ F +M KQ +D + ++K++T K + +G +S+I NP ++ L +W+ +W + + R +RL + +E + FNF +W+ R+ W++ SKSRV D FRR D D DG++TR++FI G++++ F T R EME+VA F E++G IDY++F+ AL+ D+ + + KP + + IH+E+ +Q+ C C+ + + G+ KY+ FGD++KLRL+RILRS VMVR+GGGW L EFL K+DPCR A+GRTN +LR +L G +MA FK K +L KPT + +P S R P TS +PS R +S L SPR P + + L+ +++ PT R+T G+ + SR S ++ ST + E Sbjct: 215 DELRKELDGHTPRVTSLCEASPALVENCS-PGDRAHVQSELNAVTEQWEGIEKGWQKRRGELVEVKVTSEQYHKLFVVILVWLDELELKLSEVPPVGTELATVQEQLKLHKAFHAELTPHQSEITQINQLGSTVGERCRHEDSDLVHAQLEEVNHRWDELCNHSTGRQQKLEEALLQLGQFQLAFQELLVWLRQTDSTLDEQLAKKVQGDVKYIEIELAKHKILQNDILSHEPSVDSLSRAASALLESGETDSTALEG--KVQELKTTWDAVLAKSAQRQAELEKALKDSHSFMSQIKELRGWLNEASEFLKSRRAIGGRPENATKQLNKHKDFMVVIETRQKIYVQIVEVVENLIDTADPTTAASLQRQLDELKTSWEQVTSRAAEESEKLEQALTNATSLEAQTSDMDQWLTRVDGVVSVYERPSTILVVLETQREEYKELKEDIDAHRDPYKGMRLLAHKISDVCIKEDGVYIEGIMSGLEERWKELLTTSSARKRSLDENYRMSSKFFGGVEDLMKMLDAAEEALKNEEPIGVDPAHLRTQLKKHKEFQTMLGANQAGLDATVKMGKQLMDRSLDEDAITIEGKIADLKARWDAVCGLSVERQQKLEEALLFTGMFQDALQSLLDWLFAVEPSLSTETA-VMGDPETVQILIDNHKTFQRELGRREANYQSVMKAGRAMINENKVEEPAALEEKLADLRMRWDAVYAMSNTKQDRLENALVLAKEFDSSVKTELHILKQFEENLRE--LGPIAEDLEEIKEQMEKHRVFHDELKQEEVNVQSAVKKGQVILRFCHPSAIQIIQQWLARLKKRWDEVWKWSSQRLMRLEEELRKLAEEDELMGELLRWIQTKEEALAEKEKEP--IPDDDYEEVHRLLE------EHKVFQEEMAKKQPSYDRLTKSAKRRTNGSTTRTPEVKATPSRRGGAVSRIPRSSPAGRSAHNPAVSHLSKRWQHLWLLSMERLRRLQEKLERIAIKRASAKFNFPEWKSRFNKWLHDSKSRVQDIFRRMDHDRDGKLTREQFITGVLNTSFPTERWEMEIVASKF--ERNGLIDYKEFMNALK-DKPSPE-KPKTDAQKIHNEIDRQVEHCCCAKQFSYFKVGENKYRVSHAKKERYFGDSQKLRLLRILRSTVMVRVGGGWETLQEFLEKNDPCR----------------------AEGRTNLDLRAQLVGDAGFAESMATFKSKRPSLSREGSDIGGKPTRESSGTSLRGKPPSGAR------------PKTSTSSGLTVPSVRREKSGELLSPRAPSIAKARSGSNLRAQAKSPTPGMRKTGSYGALKDAKVVSRSDSQSSIGSTGSREGE 1506
BLAST of Dystonin vs. Ensembl Nematostella
Match: EDO37708 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SF38]) HSP 1 Score: 237.269 bits (604), Expect = 1.361e-61 Identity = 129/268 (48.13%), Postives = 184/268 (68.66%), Query Frame = 3 Query: 405 DERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDI---VQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPED-VMSGIIDEKSMMTYVASLFELNPKEEDIEEKIYQFRNQYA-DLYANLNSALEELNDDFDHN 1193 D RDA+QK+TF W+N L+K+ R+ D++ +LRDG LL LLEVL + KL + + RFH L+N+ T L+FL S+ IKLVNI ++D+VDGNPKLTLGL+W IIL+FQ D+ + K DLS K LL WS+K + YP ++++NFS+SW+DG AF A+IH+ RPDL+D +SK S + N+E AF+ A+KEL VP++++ ED V+S DEKS+MTYVASL+E+ P+ ++E ++ Q + Y N L +L +D N Sbjct: 33 DHRDAVQKKTFTKWVNNRLLKVGVRILDLYEELRDGEDLLLLLEVLCNVKLPRERGLLRFHMLQNVQTALEFLESKKIKLVNIRSDDIVDGNPKLTLGLIWTIILYFQINDLDVEIAGEKVQDLSAKDALLHWSKKVTQGYPKVDVKNFSSSWRDGFAFNAIIHRYRPDLVDFSKLSKTSPEANIEYAFHVAEKELNVPRLLDVEDVVVSENPDEKSIMTYVASLYEVFPRTPTVQESLHDNEKQLKYEEYCNYAKNLVDLVNDVISN 300 HSP 2 Score: 63.929 bits (154), Expect = 2.863e-9 Identity = 33/136 (24.26%), Postives = 69/136 (50.74%), Query Frame = 3 Query: 2076 FKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRF 2483 KS +EF+ ++ + + W+ +E+ ++ W + + L++ + L+ E++ E +A G + + H A I+ L+ + S+W WI LT HL+ I++QF +A A+ ++ +QLN+ + Sbjct: 722 LKSLVEFMSEATKELIWMNQREEPEVSRDWARAD-LDLADLATYGQELLLEIKDHEPHYQGIVAKGNGMVQSGHPAPGPIEAYLSAMSSQWWWINQLTLAFDEHLKNAQIHQQFQGDAQAAEQKMVHFIDQLNTVY 856 HSP 3 Score: 57.7658 bits (138), Expect = 2.363e-7 Identity = 37/148 (25.00%), Postives = 75/148 (50.68%), Query Frame = 3 Query: 2538 RDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLREQV----LLSTMDLVKNWTP 2969 ++M + + DYK+ ++ + +S+ V+ + R + + ++ +VKA+CS K + +GE L +N+ H W+V +S E P++CF+I +A A L+ + L LW R L++ + + + + +VK+ P Sbjct: 1010 QEMKQELIDYKDIISSLQLLSKQVTPMKQRKSKL--RQKTSVKAVCSYKNMQNTVE----QGEEYTLFDNTEHHAWKVASSPGEQSEVPSVCFVIPAPDLEAIDFATRLEIQYKHLLTLWRTRHSNLKQALAKEQVFTNIKVVKSTIP 1151
BLAST of Dystonin vs. Ensembl Nematostella
Match: EDO42431 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1C0]) HSP 1 Score: 216.853 bits (551), Expect = 1.683e-55 Identity = 191/701 (27.25%), Postives = 325/701 (46.36%), Query Frame = 3 Query: 399 VADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKL-FTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDI-VQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDI-----------------EEKIYQFRNQYADLYANLNSALEELNDDFDHNDF------RIDFNQTRLENNYLTYLKQYESFCHLFDDISKVDRNNEN------QRKFHTISTLWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDGYPADQHYRIIININGKIDKVKKKFEKLSPPTLSSGVISNRQYTPIHSMELGDNVLYSSLNKWKNWIDE-KCAIISEINFTNDLDGLNKIYEKFSTTFNEIKDSVDEFKM----------ILESENKYQMDMDFHQSKN---DLKTKFNELWINCSKIDADFKSFLE---FLHKSNESIAWIKTKE---DQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEW 2348 +ADER+ +QK+TF WIN HL ++ RV ++++DL+DG L+ LLEVLS +KL R H LEN+ L FL+ Q + L N+ A D+VDGN K+TLGL+W IIL FQ +DI ++ ++ S K LL W + Y + I NF+TSW+DG AF A+IH+ RPDLI+ + ++K A+QNLE AF A+ +LG+ +++ EDV DEKS++TYVA+ + K + + EE I + +DL + + +L + N ++FNQ R + ++++ LF SK+ N++ R I+ W + E + E+ L L E + +R E ++ D + A + E + + ++ + + +I ++ E ++N ++ +EL R+ Y + ++ G+I + L +I R+ M+L ++ + +W+DE K ++SE ++ L G+ + +K S +I D K + + E K Q D Q ++ +L+ +NEL + A + L+ F ++E W+ K+ + +T I L+ K + + E+ R G L A + IQ L T++S+W Sbjct: 18 LADERERVQKKTFTKWINSHLQRVGARVNELYHDLQDGRKLILLLEVLSGEKLPKPSKGRMRIHNLENVEKSLVFLKKQRVHLENVGAHDIVDGNQKITLGLIWTIILRFQIQDITIEGETTEKRSAKDALLLWCQSKTVGYVHVTITNFTTSWRDGLAFNAIIHRHRPDLIEFEKLTKADAEQNLEQAFEVAETQLGITPLLDAEDVNVDFPDEKSILTYVAAYYHYFAKMKTVEVSGSRIGKVIERIKENEELIIDYEKLASDLLEWIEIKIIQLGEREFANTLLGVQQQMLEFNQYRTQEKPPRFVEKGNLEVQLFILTSKIRANHQKPYIPPEGRGMIDINRAWERLEKSEHERELALREELMRQERLEMLAAKFDRKYAMRETWLNENQRLVAVDNFGNDLAAVEAATKKHEAIETDIMAYEERVNAIVAVAEELHRENYHDSERIQV---CKGRI---------IQLWELLLVLIKQRRVRLEKCMQL--QRVFQEMINIIDWMDEIKIGLLSE-DYGKHLLGVEDLLQKHSLVEADIAAQADRVKTVNAQAEAFLHVEDEEGKTQHKPDEAQIRDHQAELEGAYNELLQLAAARRARLEESLKLQSFYRNADEEEMWVTEKDYFVQSTDYGHDLNTAMILLT----KHEAVEREMTARNAQTKAVARNGEELLEAVPYATDTIQNRLDTIRSKW 699 HSP 2 Score: 56.6102 bits (135), Expect = 5.143e-7 Identity = 52/212 (24.53%), Postives = 100/212 (47.17%), Query Frame = 3 Query: 17472 MTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALM--------IQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEA-KNQAI----EFERLWNSLKEFFSKSE---HELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDL 18059 M N++ W+ I K+ S+ G + V+ LL +HS++E + + ++ +N A A + Q + D + I D AEL+ +N + +LA ++ RLEE+ K Q+ + E +W + K++F +S H+L I +++ H + + + + G E+L A P A +I++ ++ I+S+W L Sbjct: 506 MINIIDWMDEI--KIGLLSEDYGKHLLGVEDLLQKHSLVEADIAAQADRVKTVNAQAEAFLHVEDEEGKTQHKPDEAQIRDHQAELEGAYNELLQLAAARRARLEESLKLQSFYRNADEEEMWVTEKDYFVQSTDYGHDLNTAMI------------LLTKHEAVEREMTARNAQTKAVARNGEELL-EAVPYATDTIQNRLDTIRSKWDKL 702
BLAST of Dystonin vs. Ensembl Nematostella
Match: EDO29101 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4L2]) HSP 1 Score: 190.274 bits (482), Expect = 2.331e-52 Identity = 125/338 (36.98%), Postives = 194/338 (57.40%), Query Frame = 3 Query: 405 DERDAMQKRTFENWINCHLMKINKRVY--DIFNDLRDGIXXXXXXEVLSDQKL-FTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLS-----IKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPK---EE--------------DIEEKIYQFRNQYADLYANLNSALEELNDDFDHNDFRID-----FNQTRLENNYLTYLKQYESFCHLFDDISKVDRNNENQRKF 1328 +ER QK+TF W+N L K+ ++ D+F DL DG +L++LLE++S +K+ F R H ++N+N L+FL+ +++KL +I AED+VDGN +L LGL+W+IIL FQ DI S DD+S K+ LL W ++ YPD++I+NFSTSW++G AF AL+HK RPDLID ++ + + NL AF A+++LG+ ++++ EDV D++S+MTYVA+ ++ K EE +IE+ + + +DL ++S + EL F+ N F + F R Y ++ HLF+ +K R NQR F Sbjct: 19 NERIFSQKKTFTKWVNSFLDKVRSGLHVNDLFEDLADGKILISLLEIISGEKIGFAARGKFRVHNIQNVNKALEFLQ-KSVKLESIGAEDVVDGNERLILGLIWMIILRFQIADI---SYQDDMSKERKSAKEALLLWCQRMTRGYPDVDIQNFSTSWRNGLAFNALLHKHRPDLIDYATLRPSQHEANLNNAFTVAEEKLGITRLLDAEDVDCPRPDDRSVMTYVAAYYQYFAKLKSEETGGRRIAKIIGVIMEIEKMEKSYESMVSDLLHWISSKITELARPFEKNIFAVQRELGAFKHFRTVEKPPKYTERVNIEAHLFNLQTK--RKANNQRPF 350
BLAST of Dystonin vs. Ensembl Nematostella
Match: EDO49576 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGP7]) HSP 1 Score: 195.667 bits (496), Expect = 1.178e-50 Identity = 135/379 (35.62%), Postives = 207/379 (54.62%), Query Frame = 3 Query: 405 DERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKL-FTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLS-----IKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPK---EE--------------DIEEKIYQFRNQYADLYANLNSALEELNDDFDHNDFRID-----FNQTRLENNYLTYLKQYESFCHLFDDISKVDRNNENQRKFHT--------ISTLWSKFETNSKEKSLILTNESKKVQRSEKIS 1433 +ER QK+TF W+N L K V D+F DL DG +L++LLE++S +K+ F R H ++N+N L+FL+ +++KL +I AED+VDGN +L LGL+W+IIL FQ DI S DD+S K+ LL W ++ YP ++I+NFSTSW++G AF AL+HK RPDLID ++ + + NL AF A ++LG+ ++++ EDV D++S+MTYVA+ ++ K EE +IE+ + + +DL ++S + EL F+ N F + F R Y ++ HLF+ +K R NQR F I+ W E+ E++ L NE + Q EK++ Sbjct: 19 NERIFSQKKTFTKWVNSFLDKSGLHVNDLFEDLADGKILISLLEIISGEKIGFAARGKFRVHNIQNVNKALEFLQ-KSVKLESIGAEDVVDGNERLILGLIWMIILRFQIADI---SYQDDMSKERKSAKEALLLWCQRMTRGYPGVDIQNFSTSWRNGLAFNALLHKHRPDLIDYATLRPSQHEANLNNAFTVAAEKLGITRLLDAEDVDCPRPDDRSVMTYVAAYYQYFAKLKSEETGGRRIAKIIGVIMEIEKMEKSYESMVSDLLHWISSKITELARPFEKNIFAVQRELGAFKHFRTVEKPPKYTERVNIEAHLFNLQTK--RKANNQRPFAPPEGKLVKDINRAWQVMESAEHERAQALRNELIRQQMLEKMA 391
BLAST of Dystonin vs. Ensembl Medaka
Match: ENSORLT00000046669.1 (pep primary_assembly:ASM223467v1:15:24337939:24343724:-1 gene:ENSORLG00000026707.1 transcript:ENSORLT00000046669.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 388.652 bits (997), Expect = 2.681e-117 Identity = 233/608 (38.32%), Postives = 361/608 (59.38%), Query Frame = 3 Query: 16938 DITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDS-KKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKT---PPL---IPIFDRSK---RMETNQGI--SKIQEPLFV-NPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKE 18722 ++ SHRE ++ LDK THLKY SQK D+VLI+NL+ S+ RWEK+V +S ER R LD K K+F + L++ + + L+ + I P KI+ Q+ +HKEF LG + YD+T R G L+DK ++D +K+D+++ L+ KW ++C KS+ER+ L +ALL SG + DA+ L+ WL +EP+L++ GD++ V L++ H + +K+L R ++ + A L+ + +DSS+++ Q+ EL + W V L+ K+ RLE+A QA EF + L E+ +++E LR P+EE E + I H F K L + +N G I+ +P++ +IKH+ IIK+++ ++ +W+ Q L L L + LL+ LL WL AE + + L + E K EH+ F+ +MT KQ D D+I K+K PP+ IP+ ++ + + Q + S Q P+ NP++N L SKW+ VW + L+RR++L D ++ L+E++ NF+F+ WR+RYM WMNH KSRVMDFFRR D D DG+VTR+EFI+GI+ SKF T+R+EM VADIFD++ Sbjct: 5 EVNSHREHIIELDKAGTHLKYFSQKKDVVLIKNLLLSVQGRWEKLVQKSVERGRLLDDARKRTKQFHETFNKLMEWLDESERTLDSEVEIANDPDKIKTQLAQHKEFQKALGSKHSVYDTTARTGRALKDKTSLRDDHQKLDDMLCELRDKWDTVCGKSVERQNKLEEALLFSGQFTDALQALIDWLYKVEPQLAEDQP-VHGDIDLVLHLIDNHKVFQKELGKRTVGVQALKRSARELIENTHDDSSWVKVQMQELSTRWETVCNLSVSKQGRLEQALCQAEEFHSTVHILLEWLAEAEQSLRFHGSLPDEE--ETLLGQIEQHKEFMKKLEEKRVSVNKATSMGEAIISICHPDSITTIKHWNTIIKARFEEVQAWARQHQQRLNLALKELLATQELLETLLNWLQWAEANISNKDMEILPQEIEEIKTLIAEHQVFMEEMTRKQPDVDKITKTHKRKAAAEPPIQSQIPVLNKGRTGRKRSPTQAMYASTTQTPIETKNPRVNLLVSKWQHVWLLALDRRRKLNDALDRLEELKEFANFDFDVWRKRYMRWMNHKKSRVMDFFRRIDKDQDGKVTRQEFIEGILSSKFPTSRLEMSAVADIFDRD 609 HSP 2 Score: 69.707 bits (169), Expect = 8.951e-11 Identity = 83/354 (23.45%), Postives = 152/354 (42.94%), Query Frame = 3 Query: 15843 KLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLT-KGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAI----EIDMEILVKKWDT--------VKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLN 16865 KL EW E L + + + TQ+ + KE + + KH + + G L K S + +++ L + D W + +RQ++L+ LL G+F A+ I+W+ E L + HGDI+ + + HK+ + ++ V ++R A E+I E+ ++++L WE + + +K LE AL +A F+ + ++ L + +F G LPD +E L ++ ++ F K E +S + S+G+AI D +K W+T V+ A + RL A++ + + +NWL E N++ Sbjct: 76 KLMEWLDESERTLDSEVEIANDPDKIKTQLAQHKEFQKALGSKHSVYDTTARTGRALKDKTSLRDDHQKLDDMLCELRDKWDTVCGKSVERQNKLEEALLFSGQFTDALQALIDWLYKVEPQLAEDQPVHGDIDLVLHLIDNHKVFQKELGKRTVGVQALKRSARELI-ENTHDDSSWVKVQMQELSTRWETVCNLSVSKQGRLEQALCQAEEFHST---VHILLEWLAEAEQSLRFHGSLPD-EEETLLGQIEQHKEFMK--------KLEEKRVSVNKATSMGEAIISICHPDSITTIKHWNTIIKARFEEVQAWARQHQQRLNLALKELLATQELLETLLNWLQWAEANIS 416 HSP 3 Score: 65.4698 bits (158), Expect = 1.773e-9 Identity = 110/512 (21.48%), Postives = 219/512 (42.77%), Query Frame = 3 Query: 16047 VNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLE----QLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQ--------LKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSI---GKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIA-SNLEILERDTSI-GQTPSKIREQITKHKEFHCNLG-----VHNLTYDSTRRL---------------GYQLRDKAPIQDS---------KKIDEIVHNLQMKWQSLCNKSIEREKALNDAL 17444 + + L + W +L+ +R L +FH ++ +EW+ +E +L + D + ++ LAQHK + + S+ SV + +K D +SL + Q+L+ +LR W+ + K E ++ L+EAL+F G + + + + K+E P A++Q + +D ++ F K K ++ +++ ++ +++ M+ L +W+TV NL+ +++ RLE+A+ E FH + + WL E++L + T+L Q+E H+ + + R + M + I I I++ + I R+E+V + + + + L+ KE +++ TLL+ + + I +D I Q +I+ I +H+ F + V +T R+ G R ++P Q + + V+ L KWQ + +++R + LNDAL Sbjct: 35 IKNLLLSVQGRWEKLVQKSVERGRLLDDARKRTKQFHETFNKLMEWLDESERTLDSEVEIANDPDKIKTQLAQHKEFQKALG-SKHSVYDTTARTGRALK-DKTSL-RDDHQKLDDMLCELRDKWDTVC----GKSVERQNKLEEALLFSGQFTDALQALIDWLYKVE--------PQLAEDQPVHGDIDLVLHLIDNHKVFQKELGKRTVGVQALKRSARELIENTHDDSSWVKVQMQELSTRWETVCNLSVSKQGRLEQALCQAEEFHSTVHILLEWLAEAEQSLRFHGSLPDEEETLLGQIEQHKEFMKKLEEKRVSVNKATSMGEAIISICHPDSITTIKHWNTIIKARFEEVQAWARQHQQRLNLALKELLATQELLETLLNWLQWAEANISNKDMEILPQEIEEIKTLIAEHQVFMEEMTRKQPDVDKITKTHKRKAAAEPPIQSQIPVLNKGRTGRKRSPTQAMYASTTQTPIETKNPRVNLLVSKWQHVWLLALDRRRKLNDAL 531 HSP 4 Score: 61.6178 bits (148), Expect = 2.902e-8 Identity = 70/311 (22.51%), Postives = 132/311 (42.44%), Query Frame = 3 Query: 16731 KWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKH-DIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKA--------LNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRC-GGDMNTVQTLLNEHSILEKQLRDRDHMIEKIN 17633 KWDTV + R+++LE+A+ F + I+WL E L + +PV + +L ++ H+ ++++ + L + A L I H D ++ M + RWE V + S + L+ +A+ F LL+ +A + L S+ + QI +HKEF L ++ + +G + I I I H W ++ E +A LN AL ++ + LL+WL+ E +S+ ++ ++TL+ EH + +++ + ++KI Sbjct: 155 KWDTVCGKSVERQNKLEEALLFSGQFTDALQALIDWLYKVEPQLAEDQPVHGDIDLVLHLIDNHKVFQKELGKRTVGVQALKRSAREL--IENTHDDSSWVKVQMQELSTRWETVCNLSVSKQGRLEQALCQAEEFHSTVHILLEWLAEAEQSLRFHGSLPDEEETLLGQIEQHKEFMKKLEEKRVSVNKATSMGEAI---ISICHPDSITTIKH-----WNTIIKARFEEVQAWARQHQQRLNLALKELLATQELLETLLNWLQWAEANISNKDMEILPQEIEEIKTLIAEHQVFMEEMTRKQPDVDKIT 455
BLAST of Dystonin vs. Ensembl Medaka
Match: pleca (plectin [Source:NCBI gene;Acc:101160251]) HSP 1 Score: 364.385 bits (934), Expect = 1.704e-99 Identity = 262/940 (27.87%), Postives = 477/940 (50.74%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQ------------KLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKIY--QFRNQYADLYANLNSALEELNDD---FDHNDFRIDFNQTRLENNYLTYLKQYESFC-----------HLFDDISKVDRNNENQ--RKFHT--ISTLWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIE---CATLTNKVEE-IESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDG--YPADQHYRIIININGKIDKVKKKFEKLSPPTLSSGVISNR-QYTPIHSMEL-----------GDNVLYSSLNKWKNWIDEKCAIISEINFTNDLD----------GLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLE---FLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLRE----QVLLSTMDLVKNWTPEDFCNL 2987 LDP +R V+R+ADERD +QK+TF W+N HL+K+ + + D++ DLRDG L++LLEVLS + +L + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +SDD++ K+ LL WS++ +E Y + +NF+TSW+DG+ F A+IHK RP LID+ + + + Q+NLE AF+ A++ELGV ++++PEDV DEKS++TYV+SL++ P+ DI++ + + ++ + Y + L+ + F+ F + + +E + +LK E+ H+F + + + +H + W + E+ +L E ++++R ++I + E C N+VE +++ +R++S K P ++ A + +L E I + VQ LK DG A+Q YR + ++ ++ ++ ++ L SGV +++ T +H++++ D V + W+++ + E + +DL GL++ E+F + K DE ++ S+ Y+ + L+ ++ +L + SK A + +E F+ + + + W+ KE++++++ W + + +S K+E + L+ ELE+RE +N A G L + H A I+ A L+++W WIL L C++THL+ Y QFF + EA+ + ++ + + ++ V + E L ++ D E + ++K + + + ++ L R + + ++ ++A+C K+ R G+ L NN+ WRV N++ + P+ICFL+ + A + LD + L +W + L+ Q L+ + ++ W F L Sbjct: 59 LDPAERAVIRIADERDRVQKKTFTKWVNKHLIKVQRHITDLYEDLRDGHNLISLLEVLSGETLQRERDVVRNVRLPREKGRMRFHKLQNVQIALDFLKHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVNGQSDDMTAKERLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFSAIIHKHRPALIDMNQVYRQTNQENLEQAFSVAERELGVTRLLDPEDVDVPHPDEKSIITYVSSLYDAMPRVPDIQDGVRANELELRWQEYYEVVTMLLQWIRHHILVFEEKKFPTSYEE--IEVLWRQFLKFKETELPAKEADKNRSKHIFKSFEGAVKAGQVKVPPGYHPLDVEKEWGRLHAAILERERLLRTEFERMERLQRIVGKVQTESGVCEEQLNQVETLLQADVRRMSSG--KAP-----QHTAEVEADLEKAEGMIRFLFNDVQLLK-DGRHLQAEQMYRRVYRLHERLVNLRSEYN----LRLKSGVAASQIPMTQLHTVQVLQQSSKSTRPELDEVTLRYAHDLLGWVEDNQRRVDEGEWGSDLANVESQLGSHRGLHQSVEEFRSKIERAK--ADESQISPVSKPAYREYL------GKLELQYGKL-LTASK--ARLRYLVELHTFVSAATKELMWLNEKEEEEVNYDWSERNTNMVS-KKENYSGLMRELELREKKVNGVQATGDKLLRDGHPARKTIEAFTAALQTQWSWILQLCCCIETHLKENTAYFQFFTDVKEAEEKMKKMQDTMRRKYTCDRSVTVTRLEDLLQDAADEKEQLAEFKTHLEGLKRKANTIVQLKPRNPTTPIKGKLPIQAVCDFKQMEITVHR----GDECALLNNTQPYKWRVVNNKGSEASVPSICFLVPPTNKDAVNSVAGLDGNLQRLHAMWQTMFVDLKSLLSWQYLMRDIHIINTWNVSMFKTL 968
BLAST of Dystonin vs. Ensembl Medaka
Match: plecb (plectin b [Source:ZFIN;Acc:ZDB-GENE-100917-2]) HSP 1 Score: 362.073 bits (928), Expect = 7.162e-99 Identity = 269/990 (27.17%), Postives = 482/990 (48.69%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPK---EEDIEEKIYQFR-NQYADLYANLNSALEELNDDFDHNDFRIDFNQTRLENNYLTYLKQYESFCHLFDDISKVDRNNENQ-----------------RKFHTIST--LWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIECATLTNKVEEIESKIRKISYPMLKTPTKEMN-----EYLASISKELCDCENQINNMIISVQELKRDGYP-ADQHYRIIININGKIDKVKKKFEKLSPPTLSSGVIS-NRQYTPIHSMELGDNVLYSSLNKWKNWIDEKCAIISEINFTNDLD----------GLNKIYEKFSTTFNEIKDSVDEFKMILESENKY-----QMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLEFLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEK----------RVNVKAICSSKENPDFYTRQFI--EGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLRE----QVLLSTMDLVKNWTPEDFCNLEP-VHRQ--KIVEILNQDANRLILDLKCANIDENEINKFHFALNQCNARFAELAHS 3146 LDP +R V+R+ADERD +QK+TF W+N HL+K + V D++ DLRDG L++LLEVLS L + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +S+D+S K+ LL WS++ E YP I +NF+TSW+DGK F A+IHK P LID+ + + S +NLE AFN A+K+LGV ++++PEDV DEKS++TYV+SL+++ P+ ++ + R +Y +L L + + F+ F + + L +Q+ F + + D++ Q +H I W + E+ +L E ++++R +++ + +E +++ +ES +L++ + +N ++ A + +EL EN I + VQ LK +P A+Q YR + ++ ++ ++ + TL++ + Q T + D+V + W++E I + +DL GL++ E F + K DE ++ S+ Y ++D+ + + N K++ L S F+ + + + W+ KE++++++ W D + ++ K++ + L+ ELE++E +N+ A+G L + H ++ A L+++W WIL L C++ HL+ Y QFF + E + ++ + ++ +G + D+L+ + +E +N + ++AL+ R+ SI+ K ++ ++A+C DF ++ +G+ L NNS W+V N P++CF++ ++ +A + +LD+ + +W + +R Q L +++W ++P +RQ K +E+ QD R D + D+ + N+C F EL HS Sbjct: 52 LDPAERAVIRIADERDRVQKKTFTKWVNKHLIKAQRHVTDLYEDLRDGHNLISLLEVLSGDTLPREKGRMRFHKLQNVQIALDFLKHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVNGQSEDMSAKEKLLFWSQRMTEGYPGIRCDNFTTSWRDGKLFNAVIHKHYPRLIDMGKVYQQSNLENLEHAFNVAEKDLGVTRLLDPEDVDVPHPDEKSIITYVSSLYDVMPRVDVQDGARANELELRWQEYYELVTILLQWIRQHAMIFEERKFPASYEEIEL------LWRQFLRFKETELPVKEGDKSRSKQIYQSFESAVHAGQVKVPPGYHPIDVEKEWGRLHAAILERERLLRIEFERLERLQRVFGKVQMESGVCDDQLSRLES--------LLQSDIRLLNAGKPAQHTAEVERELDKAENMIRLLFNDVQFLKDGRHPQAEQMYRRVYRLHERLVNLRSDYNLRLKSTLTAAQVPLTSQQTSMKVRPEIDDVTLRYVQDLLAWVEENQRRIDSAEWGSDLPSLESQLGSHRGLHQTVEDFKSKIERAKS--DEGQLSPVSKGTYREYLGKLDLQYGKLLNSSKSRLRNL-----------DSLHAFISAATKELMWLNDKEEEEVNFDWSD-RNTNMTAKKDNYSGLMRELELQEKKVNDIQALGDKLVKDGHPGKKTVETFTAALQTQWSWILQLCCCIEGHLKENTAYYQFFGDVKEVQEKMNKMQENMKKKYS-------CDGSTTATRLEDLLQDAAEEREQLNEFKTL---ITALNKRSRSIIQLKPRNPTTSIKGKMPIQAVC------DFKQQEITVHKGDECALLNNSQPFKWKVLNRSGHEALVPSVCFIVPPVNKEALDSVSSLDAGHQQMLSMWQMLHVNMRSLLSWQYLTKDFTQIRSWNITMLKTMKPEEYRQVMKNLELHYQDFMRDSQDSQQFGPDDR--MQVEGEYNRCIKHFDELIHS 995
BLAST of Dystonin vs. Ensembl Medaka
Match: pleca (plectin [Source:NCBI gene;Acc:101160251]) HSP 1 Score: 354.369 bits (908), Expect = 1.472e-96 Identity = 262/953 (27.49%), Postives = 477/953 (50.05%), Query Frame = 3 Query: 369 LDPVDRIVLRVADERDAMQKRTFENWINCHLMK-------------INKRVYDIFNDLRDGIXXXXXXEVLSDQ------------KLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKIY--QFRNQYADLYANLNSALEELNDD---FDHNDFRIDFNQTRLENNYLTYLKQYESFC-----------HLFDDISKVDRNNENQ--RKFHT--ISTLWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIE---CATLTNKVEE-IESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDG--YPADQHYRIIININGKIDKVKKKFEKLSPPTLSSGVISNR-QYTPIHSMEL-----------GDNVLYSSLNKWKNWIDEKCAIISEINFTNDL----------DGLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLE---FLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLRE----QVLLSTMDLVKNWTPEDFCNL 2987 LDP +R V+R+ADERD +QK+TF W+N HL+K + + + D++ DLRDG L++LLEVLS + +L + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +SDD++ K+ LL WS++ +E Y + +NF+TSW+DG+ F A+IHK RP LID+ + + + Q+NLE AF+ A++ELGV ++++PEDV DEKS++TYV+SL++ P+ DI++ + + ++ + Y + L+ + F+ F + + +E + +LK E+ H+F + + + +H + W + E+ +L E ++++R ++I + E C N+VE +++ +R++S K P ++ A + +L E I + VQ LK DG A+Q YR + ++ ++ ++ ++ L SGV +++ T +H++++ D V + W+++ + E + +DL GL++ E+F + K DE ++ S+ Y+ + L+ ++ +L + SK A + +E F+ + + + W+ KE++++++ W + + +S K+E + L+ ELE+RE +N A G L + H A I+ A L+++W WIL L C++THL+ Y QFF + EA+ + ++ + + ++ V + E L ++ D E + ++K + + + ++ L R + + ++ ++A+C K+ R G+ L NN+ WRV N++ + P+ICFL+ + A + LD + L +W + L+ Q L+ + ++ W F L Sbjct: 59 LDPAERAVIRIADERDRVQKKTFTKWVNKHLIKCFISLGVLRKQEEVQRHITDLYEDLRDGHNLISLLEVLSGETLQRERDVVRNVRLPREKGRMRFHKLQNVQIALDFLKHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVNGQSDDMTAKERLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFSAIIHKHRPALIDMNQVYRQTNQENLEQAFSVAERELGVTRLLDPEDVDVPHPDEKSIITYVSSLYDAMPRVPDIQDGVRANELELRWQEYYEVVTMLLQWIRHHILVFEEKKFPTSYEE--IEVLWRQFLKFKETELPAKEADKNRSKHIFKSFEGAVKAGQVKVPPGYHPLDVEKEWGRLHAAILERERLLRTEFERMERLQRIVGKVQTESGVCEEQLNQVETLLQADVRRMSSG--KAP-----QHTAEVEADLEKAEGMIRFLFNDVQLLK-DGRHLQAEQMYRRVYRLHERLVNLRSEYN----LRLKSGVAASQIPMTQLHTVQVLQQSSKSTRPELDEVTLRYAHDLLGWVEDNQRRVDEGEWGSDLANVESQLGSHRGLHQSVEEFRSKIERAK--ADESQISPVSKPAYREYL------GKLELQYGKL-LTASK--ARLRYLVELHTFVSAATKELMWLNEKEEEEVNYDWSERNTNMVS-KKENYSGLMRELELREKKVNGVQATGDKLLRDGHPARKTIEAFTAALQTQWSWILQLCCCIETHLKENTAYFQFFTDVKEAEEKMKKMQDTMRRKYTCDRSVTVTRLEDLLQDAADEKEQLAEFKTHLEGLKRKANTIVQLKPRNPTTPIKGKLPIQAVCDFKQMEITVHR----GDECALLNNTQPYKWRVVNNKGSEASVPSICFLVPPTNKDAVNSVAGLDGNLQRLHAMWQTMFVDLKSLLSWQYLMRDIHIINTWNVSMFKTL 981
BLAST of Dystonin vs. Ensembl Medaka
Match: pleca (plectin [Source:NCBI gene;Acc:101160251]) HSP 1 Score: 353.984 bits (907), Expect = 2.380e-96 Identity = 254/910 (27.91%), Postives = 464/910 (50.99%), Query Frame = 3 Query: 399 VADERDAMQKRTFENWINCHLMKINKRVYDIFNDLRDGIXXXXXXEVLSDQKLFTQNAISRFHCLENINTVLDFLRSQNIKLVNIHAEDLVDGNPKLTLGLVWIIILFFQFKDIVQSSKSDDLSIKQILLQWSRKALEDYPDINIENFSTSWKDGKAFLALIHKKRPDLIDLKSISKNSAQQNLEMAFNTAQKELGVPKIIEPEDVMSGIIDEKSMMTYVASLFELNPKEEDIEEKIY--QFRNQYADLYANLNSALEELNDD---FDHNDFRIDFNQTRLENNYLTYLKQYESFC-----------HLFDDISKVDRNNENQ--RKFHT--ISTLWSKFETNSKEKSLILTNESKKVQRSEKISVSLDIE---CATLTNKVEE-IESKIRKISYPMLKTPTKEMNEYLASISKELCDCENQINNMIISVQELKRDG--YPADQHYRIIININGKIDKVKKKFEKLSPPTLSSGVISNR-QYTPIHSMEL-----------GDNVLYSSLNKWKNWIDEKCAIISEINFTNDLD----------GLNKIYEKFSTTFNEIKDSVDEFKMILESENKYQMDMDFHQSKNDLKTKFNELWINCSKIDADFKSFLE---FLHKSNESIAWIKTKEDQQIHWQWFDTESIKLSEKQEKFKNLIDELEMRETSINETIAVGTTLTINNHSAANYIQKSLATLKSEWQWILNLTHCLKTHLECLAIYEQFFYEANEADNAILELTNQLNSRFFRPLGVGLDEGEILNREIRDMLETIEDYKETVNRIIAISQSVSALSLRTTSILPEKRVNVKAICSSKENPDFYTRQFIEGELLQLTNNSGHDMWRVCNSRNESFNAPAICFLITDISPQASQTAITLDSHFTFLKDLWTKRELQLRE----QVLLSTMDLVKNW 2963 V DERD +QK+TF W+N HL+K+ + + D++ DLRDG L++LLEVLS + L + RFH L+N+ LDFL+ + +KLVNI +D+ DGNPKLTLGL+W IIL FQ DI + +SDD++ K+ LL WS++ +E Y + +NF+TSW+DG+ F A+IHK RP LID+ + + + Q+NLE AF+ A++ELGV ++++PEDV DEKS++TYV+SL++ P+ DI++ + + ++ + Y + L+ + F+ F + + +E + +LK E+ H+F + + + +H + W + E+ +L E ++++R ++I + E C N+VE +++ +R++S K P ++ A + +L E I + VQ LK DG A+Q YR ++ ++ ++ ++ L SGV +++ T +H++++ D V + W+++ + E + +DL GL++ E+F + K DE ++ S+ Y+ + L+ ++ +L + SK A + +E F+ + + + W+ KE++++++ W + + +S K+E + L+ ELE+RE +N A G L + H A I+ A L+++W WIL L C++THL+ Y QFF + EA+ + ++ + + ++ V + E L ++ D E + ++K + + + ++ L R + + ++ ++A+C K+ R G+ L NN+ WRV N++ + P+ICFL+ + A + LD + L +W + L+ Q L+ + ++ W Sbjct: 12 VPDERDRVQKKTFTKWVNKHLIKVQRHITDLYEDLRDGHNLISLLEVLSGETLPREKGRMRFHKLQNVQIALDFLKHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVNGQSDDMTAKERLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFSAIIHKHRPALIDMNQVYRQTNQENLEQAFSVAERELGVTRLLDPEDVDVPHPDEKSIITYVSSLYDAMPRVPDIQDGVRANELELRWQEYYEVVTMLLQWIRHHILVFEEKKFPTSYEE--IEVLWRQFLKFKETELPAKEADKNRSKHIFKSFEGAVKAGQVKVPPGYHPLDVEKEWGRLHAAILERERLLRTEFERMERLQRIVGKVQTESGVCEEQLNQVETLLQADVRRMSSG--KAP-----QHTAEVEADLEKAEGMIRFLFNDVQLLK-DGRHLQAEQMYRRFYRLHERLVNLRSEYN----LRLKSGVAASQIPMTQLHTVQVLQQSSKSTRPELDEVTLRYAHDLLGWVEDNQRRVDEGEWGSDLANVESQLGSHRGLHQSVEEFRSKIERAK--ADESQISPVSKPAYREYL------GKLELQYGKL-LTASK--ARLRYLVELHTFVSAATKELMWLNEKEEEEVNYDWSERNTNMVS-KKENYSGLMRELELREKKVNGVQATGDKLLRDGHPARKTIEAFTAALQTQWSWILQLCCCIETHLKENTAYFQFFTDVKEAEEKMKKMQDTMRRKYTCDRSVTVTRLEDLLQDAADEKEQLAEFKTHLEGLKRKANTIVQLKPRNPTTPIKGKLPIQAVCDFKQMEITVHR----GDECALLNNTQPYKWRVVNNKGSEASVPSICFLVPPTNKDAVNSVAGLDGNLQRLHAMWQTMFVDLKSLLSWQYLMRDIHIINTW 891
BLAST of Dystonin vs. Planmine SMEST
Match: SMESG000043809.1 (SMESG000043809.1) HSP 1 Score: 7300.67 bits (18941), Expect = 0.000e+0 Identity = 3951/4917 (80.35%), Postives = 4183/4917 (85.07%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI---AINIDQ---TECNLFENRKL--YQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN-----EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQ---------------------------IDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKTRQYMPLSCPFTNVH---IRTIEEEMNFSI-----PQSLP-ENVLRVFSQKPNDNKNVEGLIITST---SVNLDHEIQIKTDNN------KNQVDINQADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQXXXXXXXXXXXXXXADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPXXXXXXXXXXXXXXXXXXXXESXXXXXXXXXXXXXXXXXXXQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE 19520 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + + K +L + + LT+ +A+ + L+D G I D + + IS+ E II + N ++ S+S+ E+ NI +E + KL + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E G ++ L + I+ + L + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + + + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L + E T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ + ++ + + T+ TL +A++ GL+ T+ T + P+S ++ R I + N +I QS+ +L+ FS P+ K + I + S NL+ IK++ + + +I +ADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQSGHYSGSESSGVSSADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKNLILNDEIIEIERIDEDIRNLRPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRLSKKVDNLNKLLKDRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPLDVLDSKTLLSKKLSSVFKVESDLKDLKLEADEKLEFLKKLQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYEKLELLLKFGNLLRNYLDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEI LEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNIKIEKFIEESAEISKKSSQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVSRSSERSRNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKILLDDLLLWLAAAEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCR CV S + + +KGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE Sbjct: 3224 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSDKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERID---KEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNIKKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQSELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD-PISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKNFSDVPSLFKAYDFKIDDNNFHFSNNLNTFTHIKSNLHHLSHFEEESPNIIEADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQSGHYSGSESSGVSSADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKNLILNDEIIEIERIDEDIRNLRPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRLSKKVDNLNKLLKDRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPLDVLDSKTLLSKKLSSVFKVESDLKDLKLEADEKLEFLKKLQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYEKLELLLKFGNLLRNYLDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEI--------------LEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNIKIEKFIEESAEISKKSSQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVSRSSERSRNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKILLDDLLLWLAAAEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCREA------CVPEPSNDTESIKNSKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE 8032 HSP 2 Score: 109.768 bits (273), Expect = 1.047e-22 Identity = 229/1078 (21.24%), Postives = 437/1078 (40.54%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEG-----ILSKPISI------LQIVLEKDEFPFLVD---------INNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG-----LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQL------IKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 ++ +EA+ D E+ I+D + + L + G +L+K IS+ + L++ LVD I+ ++ S+ EA+ RGIID + Q +SL E +++G L+T N K +DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + + K +L + + LT+ +A+ + L+D G I D + + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T ++D + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ ++ + + + ++++ E TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N ++ NE++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + ++++S +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LTN+ + +ID Q ++ TL +E G V TL ++ DP I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 545 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLT-NEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLNSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---------KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTKLEKISMEYSTDAHHLTLDEAMEKGLVD----TLRG------------------TIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 1557 HSP 3 Score: 103.219 bits (256), Expect = 9.808e-21 Identity = 233/1097 (21.24%), Postives = 451/1097 (41.11%), Query Frame = 3 Query: 5055 DPITNTELKYTDAIRYQYINDDISEILFVDPSEN-------------SFHLTTKEAVKNKFFDPESGNI-FDHNRDS-YIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG----LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISG----PNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI---AINIDQ---TECNLFENRKL--YQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 DPI+ TE+ +AI I+ + S I + ++ S LT+++ +K E I +++ D+ ++ L A ++G++ ++ + E S+ EA+ RGIID + Q +SL E +++G ++ N K +DK K + +S + + ++ L+E++ G I P +++L AI GIID +N + + SL E E + + K +L + + LT+ +A+ + L+D G I D + + IS+ E II + N ++ S+S+ E+ NI +E + KL + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS SV KE + + E ++ +S Y + ++EA+ G ++ + + +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T+++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ I + + I E + E+ TD + +T ++A+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E N +Y+ KG V+ ++ML + I+ L+ K + LE S+ + T + E + K + +++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 1970 DPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEI-----------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTI------------RDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKQTELEKISMEY-STDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAE---------NSAIYD---AEKGQSVS---LSEMLKSGK--NISALLTSEKERMDKEKLTELEKISMEYS--TDAHHLTLDEAMEKGLVDTLRVTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 3003 HSP 4 Score: 102.064 bits (253), Expect = 2.263e-20 Identity = 227/1087 (20.88%), Postives = 435/1087 (40.02%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAY------------ENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEG----DSERLE--------EKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + I K +L + + LT+ A+ + L+D G I D + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS SV KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ I + + I E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I E D+E+ + E+I + + ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 887 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKQTKLEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSCLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 1893 HSP 5 Score: 100.523 bits (249), Expect = 5.310e-20 Identity = 243/1108 (21.93%), Postives = 443/1108 (39.98%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISG---PNQEIIHPNLTQK-LTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKII-TENQ--YNRIVFLTCPLIKFSISIDE----------IAINIDQTECNLFE--NRKLYQTI-TTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANF-IQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDV--------KSLNNELKIIGF---------------------------KDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIV--TLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTG--KSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G + I ++ K ++L AI GIID +N + + SL E E + + K L +L + + LT+ +A+ + L+D G I D + + IS+ E II EN Y+ +C ID+ + + D L E + L T+ T+ D + ISL EA R I+ + Y + S ++ + + I KER+ + K + EKI + + ++ +A+E G++D L G I D +I + EAI G I+A + + K EL+ I +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + T+ +E+S L EAI ID + S + + G+ + L E +++ + ++ N I + TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E N +Y+ KG V+ ++ML + + Q + + K T L S A +TL E + K + ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 1481 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGTEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSCLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT---IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEIS--LQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISV---LQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGII----DAE---------NSAIYD---AEKGQSVS---LSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLD------EAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 2508 HSP 6 Score: 99.7525 bits (247), Expect = 1.054e-19 Identity = 231/1112 (20.77%), Postives = 435/1112 (39.12%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNE------QFSLKEAYENKFISKSLLKDLTVYCGITNG-NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKG-----LVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQL------IKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 ++ +EA+ D E+ I+D + + L + G K IS L Q LEK + D ++ ++ EA+ +G++D P ++ISL E + G++ I D K + L+E L SG N + N ++ ID + + + I+ E +L EA E + T+ I + + +++++ +AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ +A+E G++D L G I D +I + EAI G I+A + D G +S + ++ G L+ +K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ NS +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LTN+ + +ID Q ++ TL + +E G V TL ++ DP I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 149 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGIIDAENSAIYDAEKGQ----------SVSLSEMLKSGKNISALLTNEKER-----------IDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD-------TLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT---IRDPISGKEISLQEAIARGIIDAENS------------AIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLNSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVD----TLRG------------------TIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 1161 HSP 7 Score: 99.3673 bits (246), Expect = 1.343e-19 Identity = 243/1158 (20.98%), Postives = 462/1158 (39.90%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIV----LEKDEFPFLVDINNEKSS------ISEALVRGIIDGNSEFSIKPNFSQK-ISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNE------QFSLKEAYENKFISKSLLKDLTVYCGITNG-NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDR-------KFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQL------------------------------FIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG-----LIVNEG---DSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLT-NQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 ++ +EA+ D E+ I+D + + L + G K IS L ++K++ L I+ E S+ + EA+ +G++D +I+ S K ISL EA+ G++ I D K + L+E L SG N ++ N ++ ID + + + I+ E +L EA E + T+ I + + +++++ +AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ A+E G++D L G I D +I + EAI G I+A + + + + SG IS + EK +D+ K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I +P +G++++L+EAI I D + I S S E +K G L+ +E D E+L E +++ + Y+ H LT ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ + ++ + + T+ TL +A++ GL+ T+ T Sbjct: 2274 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVD-TLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQ----------SVSLSEMLKSGKNISVLQTNEKER-----------IDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD-------TLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDDAMEKGLVDTLRGT---IRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRVTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTE--LEKISMEYSTDAHH--------LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 3353 HSP 8 Score: 98.5969 bits (244), Expect = 2.275e-19 Identity = 230/1110 (20.72%), Postives = 439/1110 (39.55%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQ---------------------------IDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + + K L +L + + LT+ +A+ + L+D I D + + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT + E + + L + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E ID++ + ++ + + T+ TL +A++ GL+ T+ T Sbjct: 2729 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRVTIRDPISGKEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKE-------RMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSDKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 3749 HSP 9 Score: 95.9005 bits (237), Expect = 1.306e-18 Identity = 216/1007 (21.45%), Postives = 390/1007 (38.73%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGIL------------------------SKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKP-SLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQ-------------KLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDR-------KFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLI 7625 E + ++ S ++ HLT EA++ D G I D I L A GI+ K IS L Q LEK + D ++ ++ EA+ +G++D P ++ISL EA+ G++ I D K S+S + N G K +L++ + + T+ LTL A++ G++DT + I+ ++ SL+E AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ A+E G++D L G I D +I + EAI G I+A + + + + SG IS + EK +D+ K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L S E T+L I+ L L+EA+++ + D + IR + S +E++ G+I Sbjct: 689 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLNSG--KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQE---------------------------------AIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDDAMEKGLVDTLRGT---IRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTKLEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGII 1631 HSP 10 Score: 93.9745 bits (232), Expect = 5.017e-18 Identity = 222/1070 (20.75%), Postives = 415/1070 (38.79%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISIL-----------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKP-SLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQ-------------KLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINE----GYYDKIITENQYNRI---VFLTCPLIKFSISIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANF-IQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 E + ++ S ++ HLT EA++ D G I D I L A GI+ S + Q LEK + D ++ ++ +A+ +G++D P +ISL EA+ G++ I D K S+S + G K +L++ + + T+ LTL A++ G++DT +TI+ ++ SL+EA I +ID + I+D Q +S++E G ++ N+ RI I S D + +D+ E L + + T+ D ISL EA R I+ + Y + S ++ + + I KER+ + K + EKI + + ++ +A+E G++D L G +D ISG IS +AI +G++D + ++ + Q ++++E +++ +LT + E + + L + + + +TL+EA+ +D R ++ +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L + E T+L I+ L L++A+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q + ++ TL +E G V TL ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 1863 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHH--LTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEA---------------------------------IARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT------------------------------------------IRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKE-------RMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD----TLRG------------------TIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 2805 HSP 11 Score: 93.9745 bits (232), Expect = 5.593e-18 Identity = 256/1232 (20.78%), Postives = 491/1232 (39.85%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKP-SLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQ-------------KLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINE----GYYDKIITENQYNRI---VFLTCPLIKFSISIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYY-----------HEKDRI---------YYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINE---------AILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLT--------------------EKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG----LLHTIMKTR-------QYMPLSCPF-TNVHIRTIEEEMNFSIPQSLPENVLRVFSQKPNDNKNVEGLIITSTSVNLDHEIQIKTDNNKNQVDINQADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDE 8468 ++ +EA+ D E+ I+D + + L + G K IS L Q LEK + D ++ ++ EA+ +G++D P +ISL EA+ G++ I D K S+S + G K +L++ + + T+ LTL A++ G++DT +TI+ ++ SL+EA I +ID + I+D Q +S++E G + ++ R+ I S D + +D+ E L + + T+ D+ + ISL EA R I+ + Y +EK+RI S + DA+ + + K V ++ + +PI+ + +S ++A+ GIID I D + ++E A+L+ E +D++ ++ EL+ I + ++ +A+EKGLVD + S + +++ EA G + EK+ ++ T++D + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ ++ + + + ++++ E TD + +T +EA+E+G +D T RD + ++EA+A+ I+D S + +V ++++ S +N ++ NE++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L S E T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E N +Y+ KG V+ ++ML + I+ L+ K + LE S+ + T + E + K + ++ D + I+ QEAI R +I+ +S + + + +LS+ L+ G +L T K R + +S + T+ H T++E M + + LR + P K + + + +D E D K Q ++ ++ KN ++ SE E++ +Q L+++++ + + + LDE Sbjct: 1422 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTNEKERIDKEKQTKLEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEA---------------------------------IARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSCLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT------------IRDPISGKEISLQEAIARGIID---AENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQT---ELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---------KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGII----DAE---------NSAIYD---AEKGQSVS---LSEMLKSGK--NISALLTSEKERMDKEKLTELEKISMEYS--TDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLV-----DTLRGTIRDPISGKEISLQEAIARGI-IDAENSAIYDAEKGQ-SVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDE 2548 HSP 12 Score: 88.1965 bits (217), Expect = 2.968e-16 Identity = 231/1149 (20.10%), Postives = 435/1149 (37.86%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG-----LVTENGKIIVDKNKPS---------------LSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYE-NKFISKSLLKD-------------------------LTVYCGITNG-------------NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINE----GYYDKIITENQYNRI---VFLTCPLIKFSISIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANF-IQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKS--------------PKLSTNESLTSNITSLTGSNTEN--NSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG-----LIVNEGDSERLE-EKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLY-------------FENLNKRH--DNYQII---------------SVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L+T N K +DK K + L+ DA KG L+ I P +++L AI GIID +N + + SL E + K IS L + LT+ + G + +++++ +AI +ID + I+D Q +S++E G ++ N+ RI I S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + I + KER+ + K + EKI + + ++ +A+E G++D L G +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ ++ + + + ++++ E TD + +T +EA+E+G +D T RD + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S L++ K+S S ++ +L + + ++ + I +P +G++++L+EAI I D + I S S E +K G L+ +E ER++ EK + + Y + + ++ + + +D + I+DP +GK +L + G II N ++Y E ++ + D + + ++ DP I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 986 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLT-NEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKG-------LVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT------------------------------------------IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTKLEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---------KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSC-LQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSE--KERMDKEKQTELEKISMEYSTDAHHLTL-----DEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 2013 HSP 13 Score: 86.6557 bits (213), Expect = 8.028e-16 Identity = 132/601 (21.96%), Postives = 263/601 (43.76%), Query Frame = 3 Query: 6501 FKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLT----------------NQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T+++ + +GLVD G + P ++L E I ID + S + + G+ + L E +++ I + + I E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L + E T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E ID++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 140 IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 719 HSP 14 Score: 79.7221 bits (195), Expect = 1.087e-13 Identity = 134/636 (21.07%), Postives = 257/636 (40.41%), Query Frame = 3 Query: 6540 DAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEI------KLPTINDLITQG------------------LVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQL------IKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHGLLHTIMKTRQYMPLSCPF-TNVHIRTIEEEMNFSIPQSLPENVLRVFSQK 8213 +A+EKGLVD +T S + +++ EA G + E I + ++++++ G L + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++E +A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LTN+ + +ID Q ++ TL +E G V TL ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G + + T++ +S + T+ H T++E M + +L + S K Sbjct: 27 EAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD----TLRG------------------TIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKK---ISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGK 628 HSP 15 Score: 74.7146 bits (182), Expect = 3.211e-12 Identity = 131/616 (21.27%), Postives = 262/616 (42.53%), Query Frame = 3 Query: 6501 FKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQS---------------------NVTVYMT-----DVQNSVQNKTLEIPNEEKFVDT-----------KTTKTLESIKRNYFGDDQDSKLIQTVKDASIRQELPLS--VATDERITA--------VNRKPSNSMEN-AHSLGLKSPKLSTNESLTSNIT-SLTGSNTENNSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG-----LIVNEGDSERLE-EKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ I + + I E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S N++ +T + + TL+ E+ VDT K E+I R D ++S + DA Q + LS + + + I+A ++++ +E + + L+ +E++ + +L G+ I +P +G++++L+EAI I D + I S S E +K G L+ +E ER++ EK + + Y + + ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 338 IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII-DAENS----AIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT----------IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSE--KERMDKEKQTELEKISMEYSTDAHHLTL-----DEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLNSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 917 HSP 16 Score: 68.5514 bits (166), Expect = 2.361e-10 Identity = 109/500 (21.80%), Postives = 217/500 (43.40%), Query Frame = 3 Query: 6675 TINDLITQGLVDFDSGIV--TLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLS---VATDERITAVNRKPSNS----MENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 T+++ + +GLVD G + T+ +E+S L EAI ID + S + + G+ + L E +++ ++ + + + ++++ E TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D + L+ T++ +IR P+S ++ E I NS E S+ L S L + +++++ +T+ + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q + ++ TL +E G V TL ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 24 TLDEAMEKGLVDTLRGTIRDTISGKEIS--LQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---------KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEEIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD----TLRG------------------TIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 482 HSP 17 Score: 56.9954 bits (136), Expect = 8.054e-7 Identity = 90/435 (20.69%), Postives = 178/435 (40.92%), Query Frame = 3 Query: 6963 TDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTN------------------------------QMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 TD + +T +EA+E+G +D T RD + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E + G+I D+E ++ V + G ++A LTN + + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 18 TDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 436
BLAST of Dystonin vs. Planmine SMEST
Match: SMESG000043809.1 (SMESG000043809.1) HSP 1 Score: 7298.75 bits (18936), Expect = 0.000e+0 Identity = 3958/4966 (79.70%), Postives = 4197/4966 (84.51%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIV----LEKDEFPFLVDINNEKSS------ISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKP-SLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQ-------------KLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGY-YDKIIT------ENQYNRIVFLTCPLIKFSISIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANF-IQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDR-------KFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNS------------------IDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAIN-------------------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQ---------------------------IDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKTRQYMPLSCPFTNVH---IRTIEEEMNFSI-----PQSLP-ENVLRVFSQKPNDNKNVEGLIITST---SVNLDHEIQIKTDNN------KNQVDINQADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQXXXXXXXXXXXXXXADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPXXXXXXXXXXXXXXXXXXXXESXXXXXXXXXXXXXXXXXXXQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE 19520 ++ +EA+ D E+ I+D + + L + G K IS L ++K++ L I+ E S+ + EA+ +G++D P ++ISL EA+ G++ I D K S+S + G K +L++ + + LT+ LTL A++ G++DT + I+ ++ SL+EA I +ID + I+D Q +S++E DK I+ + + ++ I S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + I KER+ + K + EKI + + ++ +A+E G++D L G I D +I + EAI G I+A + + + + SG IS + EK +D+ K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L + E T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ + ++ + + T+ TL +A++ GL+ T+ T + P+S ++ R I + N +I QS+ +L+ FS P+ K + I + S NL+ IK++ + + +I +ADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQSGHYSGSESSGVSSADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKNLILNDEIIEIERIDEDIRNLRPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRLSKKVDNLNKLLKDRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPLDVLDSKTLLSKKLSSVFKVESDLKDLKLEADEKLEFLKKLQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYEKLELLLKFGNLLRNYLDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEI LEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNIKIEKFIEESAEISKKSSQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVSRSSERSRNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKILLDDLLLWLAAAEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCR CV S + + +KGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE Sbjct: 3160 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEA---------------------------------IARGIIDAENSAIYDAEKGQSVSLSEMLKSDKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT---IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSCLLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQSELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD-PISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKNFSDVPSLFKAYDFKIDDNNFHFSNNLNTFTHIKSNLHHLSHFEEESPNIIEADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQSGHYSGSESSGVSSADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKNLILNDEIIEIERIDEDIRNLRPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRLSKKVDNLNKLLKDRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPLDVLDSKTLLSKKLSSVFKVESDLKDLKLEADEKLEFLKKLQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYEKLELLLKFGNLLRNYLDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEI--------------LEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNIKIEKFIEESAEISKKSSQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVSRSSERSRNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKILLDDLLLWLAAAEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCREA------CVPEPSNDTESIKNSKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE 8032 HSP 2 Score: 108.997 bits (271), Expect = 1.879e-22 Identity = 238/1104 (21.56%), Postives = 452/1104 (40.94%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG-----LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYE-NKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKII-TEN------QYNRIVFLTCPLIKFSISIDEIAIN----IDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNY--------FGDDQDSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----------------------------------NSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG---LIVNEGDSERLE-EKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L+T N K +DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E + K IS L K +++ T+ ++ LT+ +A+ + L+D G I D + + IS+ E II EN + + V L+ ++K +I + N ID+ E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT + E + + + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L S E ++ + I +P +G++++L+EAI I D + I S S E +K G ++ + ER++ EK + + Y + + ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 406 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLT-NEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYS-TDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLS-EMLKSGKNISALLTNEKERIDK------EKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLNSGKNISALLTSEKE-------RMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLR-GTIRD--PISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTL-----DEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 1412 HSP 3 Score: 107.842 bits (268), Expect = 3.403e-22 Identity = 226/1079 (20.95%), Postives = 435/1079 (40.32%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAY------------ENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEG----DSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + I K +L + + LT+ A+ + L+D G I D + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS SV KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ I + + I E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I E D+E+ +++I + + ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 887 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKQTKLEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQKRIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 1885 HSP 4 Score: 103.605 bits (257), Expect = 6.904e-21 Identity = 232/1093 (21.23%), Postives = 437/1093 (39.98%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISIL--------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKP-SLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQ-------------KLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEA-------YEN----------KFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLP------TINDLITQGLVDFDSGIV--TLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQL------IKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 E + ++ S ++ HLT EA++ D G I D I L A GI+ S + Q LEK + D ++ ++ EA+ +G++D P ++ISL EA+ G++ I D K S+S + G K +L++ + + T+ LTL A++ G++DT + I+ ++ SL+EA EN K I K +L + + LT+ A+ + L+D G I D + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS SV KE + + E ++ +S Y + ++EA+ G ++ + + +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T+++ + +GLVD G + T+ +E+S L EAI ID + S + + G+ + L E +++ ++ + + + ++++ E TD + +T +EA+E+G +D T RD + ++EA+A+ I+D S + +V ++++ S +N ++ NE++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LTN+ + +ID Q ++ TL + +E G V TL ++ DP I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 1679 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQKRIDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQKRIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTI------------RDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEIS--LQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---------KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVD----TLRG------------------TIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 2701 HSP 5 Score: 100.138 bits (248), Expect = 7.357e-20 Identity = 231/1112 (20.77%), Postives = 435/1112 (39.12%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNE------QFSLKEAYENKFISKSLLKDLTVYCGITNG-NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKG-----LVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQL------IKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 ++ +EA+ D E+ I+D + + L + G K IS L Q LEK + D ++ ++ EA+ +G++D P ++ISL E + G++ I D K + L+E L SG N + N ++ ID + + + I+ E +L EA E + T+ I + + +++++ +AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ +A+E G++D L G I D +I + EAI G I+A + D G +S + ++ G L+ +K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ NS +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LTN+ + +ID Q ++ TL + +E G V TL ++ DP I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 149 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGIIDAENSAIYDAEKGQ----------SVSLSEMLKSGKNISALLTNEKER-----------IDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD-------TLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT---IRDPISGKEISLQEAIARGIIDAENS------------AIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLNSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVD----TLRG------------------TIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 1161 HSP 6 Score: 99.7525 bits (247), Expect = 9.941e-20 Identity = 243/1158 (20.98%), Postives = 462/1158 (39.90%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIV----LEKDEFPFLVDINNEKSS------ISEALVRGIIDGNSEFSIKPNFSQK-ISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNE------QFSLKEAYENKFISKSLLKDLTVYCGITNG-NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDR-------KFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQL------------------------------FIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG-----LIVNEG---DSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLT-NQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 ++ +EA+ D E+ I+D + + L + G K IS L ++K++ L I+ E S+ + EA+ +G++D +I+ S K ISL EA+ G++ I D K + L+E L SG N ++ N ++ ID + + + I+ E +L EA E + T+ I + + +++++ +AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ A+E G++D L G I D +I + EAI G I+A + + + + SG IS + EK +D+ K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I +P +G++++L+EAI I D + I S S E +K G L+ +E D E+L E +++ + Y+ H LT ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ + ++ + + T+ TL +A++ GL+ T+ T Sbjct: 2269 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVD-TLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQ----------SVSLSEMLKSGKNISVLQTNEKER-----------IDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD-------TLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDDAMEKGLVDTLRGT---IRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRVTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTE--LEKISMEYSTDAHH--------LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 3348 HSP 7 Score: 98.9821 bits (245), Expect = 1.628e-19 Identity = 230/1110 (20.72%), Postives = 439/1110 (39.55%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQ---------------------------IDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + + K L +L + + LT+ +A+ + L+D I D + + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT + E + + L + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E ID++ + ++ + + T+ TL +A++ GL+ T+ T Sbjct: 2724 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRVTIRDPISGKEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKE-------RMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSDKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 3744 HSP 8 Score: 97.4413 bits (241), Expect = 4.553e-19 Identity = 255/1217 (20.95%), Postives = 459/1217 (37.72%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGIL------------------------SKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKP-SLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQ-------------KLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDR-------KFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTN-------QMLTE-----------------------NQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLY-FENLNKRHDNYQII--------------------------------SVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 E + ++ S ++ HLT EA++ D G I D I L A GI+ K IS L Q LEK + D ++ ++ EA+ +G++D P ++ISL EA+ G++ I D K S+S + N G K +L++ + + T+ LTL A++ G++DT + I+ ++ SL+E AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ A+E G++D L G I D +I + EAI G I+A + + + + SG IS + EK +D+ K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L S E T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT+ + LTE +D + I+D +GK +L + G II N ++Y E KR D + ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 689 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLNSG--KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQE---------------------------------AIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDDAMEKGLVDTLRGT---IRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTKLEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARG-----IIDAENSAIYDAEKGQKRIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 1832 HSP 9 Score: 96.2857 bits (238), Expect = 1.133e-18 Identity = 227/1075 (21.12%), Postives = 427/1075 (39.72%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLV---------TENGKIIVDKNKPS---------------LSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKII-TENQ--YNRIVFLTCPLIKFSISIDEIAI-NIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 ++ +EA+ D E+ I+D + + L + G K IS L Q LEK + D ++ ++ EA+ +G++D P ++ISL EA+ G++ E G+ +DK K + L+ DA KG L+ I P +++L AI GIID +N + + SL E E + + K +L + + LT+ +A+ + L+D G I D + + IS+ E II EN Y+ + L + S I++ ++ E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ D ISG IS +AI +G++D + ++ + Q ++++E +++ +LT + E + + L + + + +TL+EA+ +D R ++ +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L + E T+L I+ L L++A+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q + ++ TL +E G V TL ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 1796 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQKRIDKEKQTELEKISMEYSTDAHHLTLDDAMEKG-------LVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKE-------RMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD----TLRG------------------TIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 2800 HSP 10 Score: 90.1225 bits (222), Expect = 9.054e-17 Identity = 244/1214 (20.10%), Postives = 456/1214 (37.56%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG-----LVTENGKIIVDKNKPS---------------LSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYE-NKFISKSLLKD-------------------------LTVYCGITNG-------------NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINE----GYYDKIITENQYNRI---VFLTCPLIKFSISIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANF-IQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERIT---------------AVNRKPSNSMEN-AHSLGLKSPKLSTNESLTSNIT-SLTGSNTENNSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG-----LIVNEGDSERLE-EKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLY-FENLNKRHDNYQII--------------------------------SVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG----LLHTIMKTR-------QYMPLSCPF-TNVHIRTIEEEMNFSIPQSLPENVLRVFSQK 8213 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L+T N K +DK K + L+ DA KG L+ I P +++L AI GIID +N + + SL E + K IS L + LT+ + G + +++++ +AI +ID + I+D Q +S++E G ++ N+ RI I S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + I + KER+ + K + EKI + + ++ +A+E G++D L G +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ ++ + + + ++++ E TD + +T +EA+E+G +D T RD + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I ++++ +E + + L+ +E++ + +L G+ I +P +G++++L+EAI I D + I S S E +K G L+ +E ER++ EK + + Y + + ++ + + +D + I+DP +GK +L + G II N ++Y E KR D + ++ DP I+ QEAI R +I+ +S + + + +LS+ L+ G L T K R + +S + T+ H T++E M + +L + S K Sbjct: 986 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLT-NEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKG-------LVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT------------------------------------------IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTKLEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---------KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQKRIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT----------IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSE--KERMDKEKQTELEKISMEYSTDAHHLTL-----DEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIYDAEKGQKRIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGK 2069 HSP 11 Score: 87.0409 bits (214), Expect = 6.459e-16 Identity = 132/601 (21.96%), Postives = 263/601 (43.76%), Query Frame = 3 Query: 6501 FKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLT----------------NQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T+++ + +GLVD G + P ++L E I ID + S + + G+ + L E +++ I + + I E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L + E T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E ID++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 140 IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 719 HSP 12 Score: 80.1073 bits (196), Expect = 8.816e-14 Identity = 134/636 (21.07%), Postives = 257/636 (40.41%), Query Frame = 3 Query: 6540 DAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEI------KLPTINDLITQG------------------LVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQL------IKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHGLLHTIMKTRQYMPLSCPF-TNVHIRTIEEEMNFSIPQSLPENVLRVFSQK 8213 +A+EKGLVD +T S + +++ EA G + E I + ++++++ G L + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++E +A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LTN+ + +ID Q ++ TL +E G V TL ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G + + T++ +S + T+ H T++E M + +L + S K Sbjct: 27 EAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD----TLRG------------------TIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKK---ISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGK 628 HSP 13 Score: 68.9366 bits (167), Expect = 1.899e-10 Identity = 109/500 (21.80%), Postives = 217/500 (43.40%), Query Frame = 3 Query: 6675 TINDLITQGLVDFDSGIV--TLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLS---VATDERITAVNRKPSNS----MENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 T+++ + +GLVD G + T+ +E+S L EAI ID + S + + G+ + L E +++ ++ + + + ++++ E TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D + L+ T++ +IR P+S ++ E I NS E S+ L S L + +++++ +T+ + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q + ++ TL +E G V TL ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 24 TLDEAMEKGLVDTLRGTIRDTISGKEIS--LQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---------KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEEIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD----TLRG------------------TIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 482 HSP 14 Score: 57.3806 bits (137), Expect = 6.871e-7 Identity = 90/435 (20.69%), Postives = 178/435 (40.92%), Query Frame = 3 Query: 6963 TDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTN------------------------------QMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 TD + +T +EA+E+G +D T RD + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E + G+I D+E ++ V + G ++A LTN + + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 18 TDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 436
BLAST of Dystonin vs. Planmine SMEST
Match: SMESG000043809.1 (SMESG000043809.1) HSP 1 Score: 7298.75 bits (18936), Expect = 0.000e+0 Identity = 3958/4966 (79.70%), Postives = 4197/4966 (84.51%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIV----LEKDEFPFLVDINNEKSS------ISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKP-SLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQ-------------KLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGY-YDKIIT------ENQYNRIVFLTCPLIKFSISIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANF-IQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDR-------KFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNS------------------IDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAIN-------------------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQ---------------------------IDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKTRQYMPLSCPFTNVH---IRTIEEEMNFSI-----PQSLP-ENVLRVFSQKPNDNKNVEGLIITST---SVNLDHEIQIKTDNN------KNQVDINQADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQXXXXXXXXXXXXXXADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPXXXXXXXXXXXXXXXXXXXXESXXXXXXXXXXXXXXXXXXXQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE 19520 ++ +EA+ D E+ I+D + + L + G K IS L ++K++ L I+ E S+ + EA+ +G++D P ++ISL EA+ G++ I D K S+S + G K +L++ + + LT+ LTL A++ G++DT + I+ ++ SL+EA I +ID + I+D Q +S++E DK I+ + + ++ I S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + I KER+ + K + EKI + + ++ +A+E G++D L G I D +I + EAI G I+A + + + + SG IS + EK +D+ K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L + E T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ + ++ + + T+ TL +A++ GL+ T+ T + P+S ++ R I + N +I QS+ +L+ FS P+ K + I + S NL+ IK++ + + +I +ADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQSGHYSGSESSGVSSADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKNLILNDEIIEIERIDEDIRNLRPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRLSKKVDNLNKLLKDRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPLDVLDSKTLLSKKLSSVFKVESDLKDLKLEADEKLEFLKKLQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYEKLELLLKFGNLLRNYLDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEI LEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNIKIEKFIEESAEISKKSSQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVSRSSERSRNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKILLDDLLLWLAAAEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCR CV S + + +KGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE Sbjct: 3157 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEA---------------------------------IARGIIDAENSAIYDAEKGQSVSLSEMLKSDKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT---IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSCLLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQSELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD-PISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKNFSDVPSLFKAYDFKIDDNNFHFSNNLNTFTHIKSNLHHLSHFEEESPNIIEADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQSGHYSGSESSGVSSADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKNLILNDEIIEIERIDEDIRNLRPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRLSKKVDNLNKLLKDRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPLDVLDSKTLLSKKLSSVFKVESDLKDLKLEADEKLEFLKKLQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYEKLELLLKFGNLLRNYLDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEI--------------LEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNIKIEKFIEESAEISKKSSQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVSRSSERSRNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKILLDDLLLWLAAAEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCREA------CVPEPSNDTESIKNSKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE 8029 HSP 2 Score: 108.997 bits (271), Expect = 1.848e-22 Identity = 238/1104 (21.56%), Postives = 452/1104 (40.94%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG-----LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYE-NKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKII-TEN------QYNRIVFLTCPLIKFSISIDEIAIN----IDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNY--------FGDDQDSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----------------------------------NSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG---LIVNEGDSERLE-EKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L+T N K +DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E + K IS L K +++ T+ ++ LT+ +A+ + L+D G I D + + IS+ E II EN + + V L+ ++K +I + N ID+ E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT + E + + + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L S E ++ + I +P +G++++L+EAI I D + I S S E +K G ++ + ER++ EK + + Y + + ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 406 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLT-NEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYS-TDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLS-EMLKSGKNISALLTNEKERIDK------EKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLNSGKNISALLTSEKE-------RMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLR-GTIRD--PISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTL-----DEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 1412 HSP 3 Score: 108.227 bits (269), Expect = 2.807e-22 Identity = 229/1079 (21.22%), Postives = 436/1079 (40.41%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAY------------ENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEG----DSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + I K +L + + LT+ A+ + L+D G I D + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS SV KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ I + + I E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I E D+E+ + K Q + Y +T ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 887 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKQTKLEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLT---LDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 1882 HSP 4 Score: 100.138 bits (248), Expect = 7.357e-20 Identity = 231/1112 (20.77%), Postives = 435/1112 (39.12%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNE------QFSLKEAYENKFISKSLLKDLTVYCGITNG-NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKG-----LVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQL------IKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 ++ +EA+ D E+ I+D + + L + G K IS L Q LEK + D ++ ++ EA+ +G++D P ++ISL E + G++ I D K + L+E L SG N + N ++ ID + + + I+ E +L EA E + T+ I + + +++++ +AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ +A+E G++D L G I D +I + EAI G I+A + D G +S + ++ G L+ +K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ NS +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LTN+ + +ID Q ++ TL + +E G V TL ++ DP I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 149 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGIIDAENSAIYDAEKGQ----------SVSLSEMLKSGKNISALLTNEKER-----------IDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD-------TLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT---IRDPISGKEISLQEAIARGIIDAENS------------AIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLNSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVD----TLRG------------------TIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 1161 HSP 5 Score: 99.7525 bits (247), Expect = 9.858e-20 Identity = 243/1158 (20.98%), Postives = 462/1158 (39.90%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIV----LEKDEFPFLVDINNEKSS------ISEALVRGIIDGNSEFSIKPNFSQK-ISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNE------QFSLKEAYENKFISKSLLKDLTVYCGITNG-NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDR-------KFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQL------------------------------FIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG-----LIVNEG---DSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLT-NQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 ++ +EA+ D E+ I+D + + L + G K IS L ++K++ L I+ E S+ + EA+ +G++D +I+ S K ISL EA+ G++ I D K + L+E L SG N ++ N ++ ID + + + I+ E +L EA E + T+ I + + +++++ +AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ A+E G++D L G I D +I + EAI G I+A + + + + SG IS + EK +D+ K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I +P +G++++L+EAI I D + I S S E +K G L+ +E D E+L E +++ + Y+ H LT ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ + ++ + + T+ TL +A++ GL+ T+ T Sbjct: 2266 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVD-TLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQ----------SVSLSEMLKSGKNISVLQTNEKER-----------IDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD-------TLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDDAMEKGLVDTLRGT---IRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRVTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTE--LEKISMEYSTDAHH--------LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 3345 HSP 6 Score: 98.9821 bits (245), Expect = 1.601e-19 Identity = 230/1110 (20.72%), Postives = 439/1110 (39.55%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQ---------------------------IDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + + K L +L + + LT+ +A+ + L+D I D + + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT + E + + L + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E ID++ + ++ + + T+ TL +A++ GL+ T+ T Sbjct: 2721 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRVTIRDPISGKEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKE-------RMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSDKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 3741 HSP 7 Score: 98.5969 bits (244), Expect = 2.294e-19 Identity = 257/1213 (21.19%), Postives = 471/1213 (38.83%), Query Frame = 3 Query: 5055 DPITNTELKYTDAIRYQYINDDISEILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQK-ISLFEAVQNGLVTENGKIIVDKNKP-SLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQ-------------KLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEK-----------------LTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNN------EKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDR-------KFENFWNTKSNQILTMNEAEDLGFVLTEKLEI------KLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLG----LKSPK----LSTNES-----------------LTSNITSLTGSNTEN----NSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG-----LIVNEGDSERLE-EKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 DPI+ TE ++ +EA+ D E+ I+D + + L + G K IS L Q LEK + D ++ ++ EA+ +G++D +I+ S K ISL EA+ G++ I D K S+S + G K +L++ + + LT+ LTL A++ G++DT +TI+ ++ SL+EA I ++ +Y N EK LT+ +A+ + L+D G I D + + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N EK ++R+ + K + EKI + + ++ A+E G++D L G I D +I + EAI G I+A + + + + SG IS + EK +D+ K ++T ++ LT++EA + G V T + I K ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RD + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ LKS K L TNE +++ LT ++ + I +P +G++++L+EAI I D + I S S E +K G L+ +E ER++ EK + + Y + + ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E ID++ ++ + + T+ TL DA++ GL+ T+ T Sbjct: 1514 DPISGTE------------------------------ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVD-TLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDA---ENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQKRIDKEKQTELEKISMEYSTDAHH------LTLDDAMEKGLVDTLRGT---IRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSE--KERMDKEKQTELEKISMEYSTDAHHLTL-----DEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGT 2652 HSP 8 Score: 98.2117 bits (243), Expect = 2.948e-19 Identity = 249/1190 (20.92%), Postives = 459/1190 (38.57%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGIL------------------------SKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKP-SLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQ-------------KLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDR-------KFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTN-------QMLTE-----------------------NQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLY----FENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHGLL 8072 E + ++ S ++ HLT EA++ D G I D I L A GI+ K IS L Q LEK + D ++ ++ EA+ +G++D P ++ISL EA+ G++ I D K S+S + N G K +L++ + + T+ LTL A++ G++DT + I+ ++ SL+E AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ A+E G++D L G I D +I + EAI G I+A + + + + SG IS + EK +D+ K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L S E T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT+ + LTE +D + I+D +GK +L + G II N ++Y +N K+ + +I Y + L T EA+++ +++ + T + + + +L +A+ G++ Sbjct: 689 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLNSG--KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQE---------------------------------AIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDDAMEKGLVDTLRGT---IRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTKLEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARG-----IIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHL-TLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII 1804 HSP 9 Score: 96.2857 bits (238), Expect = 1.152e-18 Identity = 227/1075 (21.12%), Postives = 427/1075 (39.72%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLV---------TENGKIIVDKNKPS---------------LSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKII-TENQ--YNRIVFLTCPLIKFSISIDEIAI-NIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 ++ +EA+ D E+ I+D + + L + G K IS L Q LEK + D ++ ++ EA+ +G++D P ++ISL EA+ G++ E G+ +DK K + L+ DA KG L+ I P +++L AI GIID +N + + SL E E + + K +L + + LT+ +A+ + L+D G I D + + IS+ E II EN Y+ + L + S I++ ++ E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ D ISG IS +AI +G++D + ++ + Q ++++E +++ +LT + E + + L + + + +TL+EA+ +D R ++ +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L + E T+L I+ L L++A+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q + ++ TL +E G V TL ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 1793 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQKRIDKEKQTELEKISMEYSTDAHHLTLDDAMEKG-------LVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKE-------RMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD----TLRG------------------TIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 2797 HSP 10 Score: 92.0485 bits (227), Expect = 1.944e-17 Identity = 246/1211 (20.31%), Postives = 458/1211 (37.82%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG-----LVTENGKIIVDKNKPS---------------LSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYE-NKFISKSLLKD-------------------------LTVYCGITNG-------------NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINE----GYYDKIITENQYNRI---VFLTCPLIKFSISIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANF-IQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERI-----TAV-------NRKPSNSMEN-AHSLGLKSPKLSTNESLTSNIT-SLTGSNTENNSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG-----LIVNEGDSERLE-EKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLY-FENLNKRHDNYQII--------------------------------SVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG----LLHTIMKTR-------QYMPLSCPF-TNVHIRTIEEEMNFSIPQSLPENVLRVFSQK 8213 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L+T N K +DK K + L+ DA KG L+ I P +++L AI GIID +N + + SL E + K IS L + LT+ + G + +++++ +AI +ID + I+D Q +S++E G ++ N+ RI I S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + I + KER+ + K + EKI + + ++ +A+E G++D L G +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ ++ + + + ++++ E TD + +T +EA+E+G +D T RD + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I +A+ N++ +E + + L+ +E++ + +L G+ I +P +G++++L+EAI I D + I S S E +K G L+ +E ER++ EK + + Y + + ++ + + +D + I+DP +GK +L + G II N ++Y E KR D + ++ DP I+ QEAI R +I+ +S + + + +LS+ L+ G L T K R + +S + T+ H T++E M + +L + S K Sbjct: 986 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLT-NEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKG-------LVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT------------------------------------------IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTKLEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---------KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT----------IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSE--KERMDKEKQTELEKISMEYSTDAHHLTL-----DEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIYDAEKGQKRIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGK 2066 HSP 11 Score: 87.0409 bits (214), Expect = 6.352e-16 Identity = 132/601 (21.96%), Postives = 263/601 (43.76%), Query Frame = 3 Query: 6501 FKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLT----------------NQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T+++ + +GLVD G + P ++L E I ID + S + + G+ + L E +++ I + + I E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L + E T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E ID++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 140 IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 719 HSP 12 Score: 80.1073 bits (196), Expect = 8.670e-14 Identity = 134/636 (21.07%), Postives = 257/636 (40.41%), Query Frame = 3 Query: 6540 DAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEI------KLPTINDLITQG------------------LVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQL------IKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHGLLHTIMKTRQYMPLSCPF-TNVHIRTIEEEMNFSIPQSLPENVLRVFSQK 8213 +A+EKGLVD +T S + +++ EA G + E I + ++++++ G L + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++E +A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LTN+ + +ID Q ++ TL +E G V TL ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G + + T++ +S + T+ H T++E M + +L + S K Sbjct: 27 EAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD----TLRG------------------TIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKK---ISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGK 628 HSP 13 Score: 68.9366 bits (167), Expect = 1.884e-10 Identity = 109/500 (21.80%), Postives = 217/500 (43.40%), Query Frame = 3 Query: 6675 TINDLITQGLVDFDSGIV--TLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLS---VATDERITAVNRKPSNS----MENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 T+++ + +GLVD G + T+ +E+S L EAI ID + S + + G+ + L E +++ ++ + + + ++++ E TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D + L+ T++ +IR P+S ++ E I NS E S+ L S L + +++++ +T+ + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q + ++ TL +E G V TL ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 24 TLDEAMEKGLVDTLRGTIRDTISGKEIS--LQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---------KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEEIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD----TLRG------------------TIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 482 HSP 14 Score: 57.3806 bits (137), Expect = 6.871e-7 Identity = 90/435 (20.69%), Postives = 178/435 (40.92%), Query Frame = 3 Query: 6963 TDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTN------------------------------QMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 TD + +T +EA+E+G +D T RD + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E + G+I D+E ++ V + G ++A LTN + + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 18 TDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 436
BLAST of Dystonin vs. Planmine SMEST
Match: SMESG000043809.1 (SMESG000043809.1) HSP 1 Score: 7244.43 bits (18795), Expect = 0.000e+0 Identity = 3711/3732 (99.44%), Postives = 3715/3732 (99.54%), Query Frame = 3 Query: 8325 QADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQXXXXXXXXXXXXXXADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPXXXXXXXXXXXXXXXXXXXXESXXXXXXXXXXXXXXXXXXXQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE 19520 +ADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQSGHYSGSESSGVSSADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKNLILNDEIIEIERIDEDIRNLRPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRLSKKVDNLNKLLKDRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPLDVLDSKTLLSKKLSSVFKVESDLKDLKLEADEKLEFLKKLQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYEKLELLLKFGNLLRNYLDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNIKIEKFIEESAEISKKSSQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVSRSSERSRNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKILLDDLLLWLAAAEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCR CV S + + +KGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE Sbjct: 4580 KADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQSGHYSGSESSGVSSADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKNLILNDEIIEIERIDEDIRNLRPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRLSKKVDNLNKLLKDRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPLDVLDSKTLLSKKLSSVFKVESDLKDLKLEADEKLEFLKKLQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYEKLELLLKFGNLLRNYLDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNIKIEKFIEESAEISKKSSQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVSRSSERSRNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKILLDDLLLWLAAAEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCREA------CVPEPSNDTESIKNSKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE 8305 HSP 2 Score: 107.842 bits (268), Expect = 3.866e-22 Identity = 238/1104 (21.56%), Postives = 452/1104 (40.94%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG-----LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYE-NKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKII-TEN------QYNRIVFLTCPLIKFSISIDEIAIN----IDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNY--------FGDDQDSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----------------------------------NSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG---LIVNEGDSERLE-EKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L+T N K +DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E + K IS L K +++ T+ ++ LT+ +A+ + L+D G I D + + IS+ E II EN + + V L+ ++K +I + N ID+ E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT + E + + + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L S E ++ + I +P +G++++L+EAI I D + I S S E +K G ++ + ER++ EK + + Y + + ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 406 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLT-NEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYS-TDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLS-EMLKSGKNISALLTNEKERIDK------EKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLNSGKNISALLTSEKE-------RMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLR-GTIRD--PISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTL-----DEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 1412 HSP 3 Score: 107.071 bits (266), Expect = 6.278e-22 Identity = 229/1079 (21.22%), Postives = 436/1079 (40.41%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAY------------ENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEG----DSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + I K +L + + LT+ A+ + L+D G I D + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS SV KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ I + + I E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I E D+E+ + K Q + Y +T ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 887 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKQTKLEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLT---LDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 1882 HSP 4 Score: 103.605 bits (257), Expect = 7.458e-21 Identity = 240/1102 (21.78%), Postives = 439/1102 (39.84%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISG---PNQEIIHPNLTQK-LTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKII---------TENQYNRIVFLTCPLIKFSISIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANF-IQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDV--------KSLNNELKIIGF---------------------------KDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIV--TLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTG--KSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G + I ++ K ++L AI GIID +N + + SL E E + + K L +L + + LT+ +A+ + L+D G I D + + IS+ E II E N+ I S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + I KER+ + K + EKI + + ++ +A+E G++D L G I D +I + EAI G I+A + + K EL+ I +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + T+ +E+S L EAI ID + S + + G+ + L E +++ + ++ N I + TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E N +Y+ KG V+ ++ML + + Q + + K T L S A +TL E + K + ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 1481 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGTEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT---IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEIS--LQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISV---LQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGII----DAE---------NSAIYD---AEKGQSVS---LSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLD------EAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 2497 HSP 5 Score: 102.449 bits (254), Expect = 1.493e-20 Identity = 233/1097 (21.24%), Postives = 451/1097 (41.11%), Query Frame = 3 Query: 5055 DPITNTELKYTDAIRYQYINDDISEILFVDPSEN-------------SFHLTTKEAVKNKFFDPESGNI-FDHNRDS-YIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG----LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISG----PNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI---AINIDQ---TECNLFENRKL--YQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 DPI+ TE+ +AI I+ + S I + ++ S LT+++ +K E I +++ D+ ++ L A ++G++ ++ + E S+ EA+ RGIID + Q +SL E +++G ++ N K +DK K + +S + + ++ L+E++ G I P +++L AI GIID +N + + SL E E + + K +L + + LT+ +A+ + L+D G I D + + IS+ E II + N ++ S+S+ E+ NI +E + KL + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS SV KE + + E ++ +S Y + ++EA+ G ++ + + +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T+++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ I + + I E + E+ TD + +T ++A+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E N +Y+ KG V+ ++ML + I+ L+ K + LE S+ + T + E + K + +++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 1959 DPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEI-----------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTI------------RDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKQTELEKISMEY-STDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAE---------NSAIYD---AEKGQSVS---LSEMLKSGK--NISALLTSEKERMDKEKLTELEKISMEYS--TDAHHLTLDEAMEKGLVDTLRVTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 2992 HSP 6 Score: 99.3673 bits (246), Expect = 1.500e-19 Identity = 231/1112 (20.77%), Postives = 435/1112 (39.12%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNE------QFSLKEAYENKFISKSLLKDLTVYCGITNG-NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKG-----LVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQL------IKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 ++ +EA+ D E+ I+D + + L + G K IS L Q LEK + D ++ ++ EA+ +G++D P ++ISL E + G++ I D K + L+E L SG N + N ++ ID + + + I+ E +L EA E + T+ I + + +++++ +AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ +A+E G++D L G I D +I + EAI G I+A + D G +S + ++ G L+ +K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ NS +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LTN+ + +ID Q ++ TL + +E G V TL ++ DP I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 149 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGIIDAENSAIYDAEKGQ----------SVSLSEMLKSGKNISALLTNEKER-----------IDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD-------TLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT---IRDPISGKEISLQEAIARGIIDAENS------------AIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLNSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVD----TLRG------------------TIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 1161 HSP 7 Score: 98.9821 bits (245), Expect = 1.788e-19 Identity = 213/1021 (20.86%), Postives = 403/1021 (39.47%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQN-----GLVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEI-KLP----------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQ---------------------------IDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLY 7883 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++ L+T K +DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + + K L +L + + LT+ +A+ + L+D G I D + + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E G + ++ E+ K+ T+++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ ++ + + + ++++ E TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q +D + I+DP +GK +L + G II N ++Y Sbjct: 3312 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSDKNISALLTSE-KERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNIKKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---------KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQSELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY 4249 HSP 8 Score: 98.5969 bits (244), Expect = 2.279e-19 Identity = 243/1158 (20.98%), Postives = 462/1158 (39.90%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIV----LEKDEFPFLVDINNEKSS------ISEALVRGIIDGNSEFSIKPNFSQK-ISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNE------QFSLKEAYENKFISKSLLKDLTVYCGITNG-NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDR-------KFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQL------------------------------FIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG-----LIVNEG---DSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLT-NQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 ++ +EA+ D E+ I+D + + L + G K IS L ++K++ L I+ E S+ + EA+ +G++D +I+ S K ISL EA+ G++ I D K + L+E L SG N ++ N ++ ID + + + I+ E +L EA E + T+ I + + +++++ +AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ A+E G++D L G I D +I + EAI G I+A + + + + SG IS + EK +D+ K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I +P +G++++L+EAI I D + I S S E +K G L+ +E D E+L E +++ + Y+ H LT ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ + ++ + + T+ TL +A++ GL+ T+ T Sbjct: 2263 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVD-TLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQ----------SVSLSEMLKSGKNISVLQTNEKER-----------IDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD-------TLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDDAMEKGLVDTLRGT---IRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRVTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTE--LEKISMEYSTDAHH--------LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 3342 HSP 9 Score: 98.2117 bits (243), Expect = 3.184e-19 Identity = 230/1110 (20.72%), Postives = 439/1110 (39.55%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQ---------------------------IDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + + K L +L + + LT+ +A+ + L+D I D + + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT + E + + L + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E ID++ + ++ + + T+ TL +A++ GL+ T+ T Sbjct: 2718 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRVTIRDPISGKEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKE-------RMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSDKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 3738 HSP 10 Score: 97.0561 bits (240), Expect = 7.408e-19 Identity = 249/1190 (20.92%), Postives = 459/1190 (38.57%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGIL------------------------SKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKP-SLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQ-------------KLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDR-------KFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----NSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTN-------QMLTE-----------------------NQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLY----FENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHGLL 8072 E + ++ S ++ HLT EA++ D G I D I L A GI+ K IS L Q LEK + D ++ ++ EA+ +G++D P ++ISL EA+ G++ I D K S+S + N G K +L++ + + T+ LTL A++ G++DT + I+ ++ SL+E AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ A+E G++D L G I D +I + EAI G I+A + + + + SG IS + EK +D+ K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L S E T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT+ + LTE +D + I+D +GK +L + G II N ++Y +N K+ + +I Y + L T EA+++ +++ + T + + + +L +A+ G++ Sbjct: 689 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLNSG--KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQE---------------------------------AIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDDAMEKGLVDTLRGT---IRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTKLEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARG-----IIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHL-TLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII 1804 HSP 11 Score: 93.5893 bits (231), Expect = 6.735e-18 Identity = 217/1068 (20.32%), Postives = 409/1068 (38.30%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISIL-----------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKP-SLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQ-------------KLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINE----GYYDKIITENQYNRI---VFLTCPLIKFSISIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANF-IQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 E + ++ S ++ HLT EA++ D G I D I L A GI+ S + Q LEK + D ++ ++ +A+ +G++D P +ISL EA+ G++ I D K S+S + G K +L++ + + T+ LTL A++ G++DT +TI+ ++ SL+EA I +ID + I+D Q +S++E G ++ N+ RI I S D + +D+ E L + + T+ D ISL EA R I+ + Y + S ++ + + I KER+ + K + EKI + + ++ +A+E G++D L G +D ISG IS +AI +G++D + ++ + Q ++++E +++ +LT + E + + L + + + +TL+EA+ +D R ++ +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +T+ + T+L I+ L L++A+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q + ++ TL +E G V TL ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 1852 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHH--LTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEA---------------------------------IARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT------------------------------------------IRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKE-------RMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD----TLRG------------------TIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 2794 HSP 12 Score: 91.6633 bits (226), Expect = 3.163e-17 Identity = 231/1147 (20.14%), Postives = 438/1147 (38.19%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG-----LVTENGKIIVDKNKPS---------------LSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYE-NKFISKSLLKD-------------------------LTVYCGITNG-------------NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINE----GYYDKIITENQYNRI---VFLTCPLIKFSISIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANF-IQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERI-----TAV-------NRKPSNSMEN-AHSLGLKSPKLSTNESLTSNIT-SLTGSNTENNSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG-----LIVNEGDSERLE-EKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLY-------------FENLNKRH--DNYQII---------------SVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L+T N K +DK K + L+ DA KG L+ I P +++L AI GIID +N + + SL E + K IS L + LT+ + G + +++++ +AI +ID + I+D Q +S++E G ++ N+ RI I S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + I + KER+ + K + EKI + + ++ +A+E G++D L G +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ ++ + + + ++++ E TD + +T +EA+E+G +D T RD + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I +A+ N++ +E + + L+ +E++ + +L G+ I +P +G++++L+EAI I D + I S S E +K G L+ +E ER++ EK + + Y + + ++ + + +D + I+DP +GK +L + G II N ++Y E ++ + D + + ++ DP I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 986 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLT-NEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKG-------LVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT------------------------------------------IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTKLEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---------KNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT----------IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSE--KERMDKEKQTELEKISMEYSTDAHHLTL-----DEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 2002 HSP 13 Score: 89.7373 bits (221), Expect = 1.146e-16 Identity = 240/1112 (21.58%), Postives = 445/1112 (40.02%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFIS----INEGYYD---KIITENQYNRIVFLTCPLIKFSISIDEIAINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIIT-LNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNVTVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----------------------------------NSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG-----LIVNEG---DSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLT-NQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + + K L +L + + LT+ +A+ + L+D G I D + + IS I G D I + + + V L+ ++K +I A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ N ++T + I+++ E TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D N +Y + SV E+ K + +T LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L S E ++ + I +P +G++++L+EAI I D + I S S E +K G L+ NE D E+L E +++ + Y+ H LT ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 3114 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLS-EMLKSDKNIS--ALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG----------KNISALLTNEKERIDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIID--AENSAIYDAEKGQSVS--LSEMLKSGKNIKKQT--ELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTE--LEKISMEYSTDAHH--------LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 4121 HSP 14 Score: 89.7373 bits (221), Expect = 1.185e-16 Identity = 239/1145 (20.87%), Postives = 433/1145 (37.82%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIV----LEKDEFPFLVDINNEKSS------ISEALVRGIIDGNSEFSIKPNFSQK-ISLFEAVQNGLVTENGKIIVD----KNKPSLSFLDAFNKGY------IKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKII---------TENQYNRIVFLTCPLIKFSISIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANF-IQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEA---------------IDEDVKSLNN------------------ELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQL------IKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 ++ +EA+ D E+ I+D + + L + G K IS L ++K++ L I+ E S+ + EA+ +G++D +I+ S K ISL EA+ G++ I D +NK + L+ + Y + L+E++ G I P ++++L AI GIID +N + + SL E E + + K +L + + LT+ +A+ + L+D G I D + + IS+ E II E N+ I S D + +D E L + + T+ D ISL EA R I+ + Y + S ++ + + I KER+ + K + EKI + + ++ +A+E G++D L G I D +I + EAI G I+A + E +KS N EL+ I + ++ +A+EKGLVD + S +++ EA I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RD + ++EA+A+ I+D S + +V ++++ S +N ++ NE++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LTN+ + +ID Q ++ TL + +E G V TL ++ DP I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 1620 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVD-TLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLR-----GTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT---IRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEA---------------------IARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVD----TLRG------------------TIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 2695 HSP 15 Score: 86.6557 bits (213), Expect = 8.041e-16 Identity = 127/599 (21.20%), Postives = 257/599 (42.90%), Query Frame = 3 Query: 6501 FKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLT----------------NQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T+++ + +GLVD G + P ++L E I ID + S + + G+ + L E +++ I + + I E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +T+ + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E ID++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 140 IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 719 HSP 16 Score: 82.8037 bits (203), Expect = 1.346e-14 Identity = 162/750 (21.60%), Postives = 302/750 (40.27%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKP-SLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQ-------------KLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYENKFISK--SLLKD------LTVYCGITNGNNEK------------------LTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI---AINIDQ---TECNLFENRKL--YQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNVTVYMTDVQNSV 7148 ++ +EA+ D E+ I+D + + L + G K IS L Q LEK + D ++ ++ EA+ +G++D P ++ISL EA+ G++ I D K S+S + G K +L++ + I LT+ LTL A++ G++DT + I+ ++ SL+EA I S + D +++ + +G N K LT+ +A+ + L+D G I D + + IS+ E II + N ++ S+S+ E+ NI +E + KL + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT + E + + + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D N +Y + SV Sbjct: 3550 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNIKKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKE-------RMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQSELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIID--AENSAIYDAEKGQSV 4257 HSP 17 Score: 79.7221 bits (195), Expect = 1.163e-13 Identity = 134/636 (21.07%), Postives = 257/636 (40.41%), Query Frame = 3 Query: 6540 DAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEI------KLPTINDLITQG------------------LVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQL------IKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHGLLHTIMKTRQYMPLSCPF-TNVHIRTIEEEMNFSIPQSLPENVLRVFSQK 8213 +A+EKGLVD +T S + +++ EA G + E I + ++++++ G L + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++E +A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LTN+ + +ID Q ++ TL +E G V TL ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G + + T++ +S + T+ H T++E M + +L + S K Sbjct: 27 EAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD----TLRG------------------TIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKK---ISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGK 628 HSP 18 Score: 68.5514 bits (166), Expect = 2.423e-10 Identity = 109/500 (21.80%), Postives = 217/500 (43.40%), Query Frame = 3 Query: 6675 TINDLITQGLVDFDSGIV--TLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQ--------DSKLIQTVKDASIRQELPLS---VATDERITAVNRKPSNS----MENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 T+++ + +GLVD G + T+ +E+S L EAI ID + S + + G+ + L E +++ ++ + + + ++++ E TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D + L+ T++ +IR P+S ++ E I NS E S+ L S L + +++++ +T+ + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q + ++ TL +E G V TL ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 24 TLDEAMEKGLVDTLRGTIRDTISGKEIS--LQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---------KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-GTIRD--PISGKEISLQEEIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD----TLRG------------------TIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 482 HSP 19 Score: 57.3806 bits (137), Expect = 6.935e-7 Identity = 90/435 (20.69%), Postives = 178/435 (40.92%), Query Frame = 3 Query: 6963 TDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTN------------------------------QMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 TD + +T +EA+E+G +D T RD + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E + G+I D+E ++ V + G ++A LTN + + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 18 TDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 436
BLAST of Dystonin vs. Planmine SMEST
Match: SMESG000043809.1 (SMESG000043809.1) HSP 1 Score: 7244.43 bits (18795), Expect = 0.000e+0 Identity = 3711/3732 (99.44%), Postives = 3715/3732 (99.54%), Query Frame = 3 Query: 8325 QADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQXXXXXXXXXXXXXXADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKXXXXXXXXXXXXXXXXXXXXXXPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRXXXXXXXXXXXXXXRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPXXXXXXXXXXXXXXXXXXXXESXXXXXXXXXXXXXXXXXXXQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYXXXXXXXXXXXXXXXXXDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNXXXXXXXXXXXXXXXXXXQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVXXXXXXXXNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKIXXXXXXXXXXXXEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCRVLHCGDCECVCHFSMSSLELLEAKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE 19520 +ADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQSGHYSGSESSGVSSADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKNLILNDEIIEIERIDEDIRNLRPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRLSKKVDNLNKLLKDRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPLDVLDSKTLLSKKLSSVFKVESDLKDLKLEADEKLEFLKKLQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYEKLELLLKFGNLLRNYLDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNIKIEKFIEESAEISKKSSQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVSRSSERSRNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKILLDDLLLWLAAAEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCR CV S + + +KGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE Sbjct: 4583 KADAPNFAKNYIEMVKSEMEKLSVIEQKLLKEVNVFLNEKENQMLLDEFQDVNNEFVSQQTLVLTLIHEIEKFLMKKYDTIPLEIEKDLEETTNLLKTHTNQTHKELNNRSRLLIAIIDEFDQFINRLNDCTSAHDKLKLSIDKISNVKSVEDLQKSLTDLKLLDNEFASYNNDIRVLIGSKIKFIDKINKLEEQRKKFSDLVKVPLVSNQDSKTDQEITELLNEVTDGQKDLQDLYKTKLSQIKDVLENLENLAEKQKKIDKICENSREELQKILSNKEELSIHSLLPHTDNLHRLNGEMVSTSKIIKEIEDSLQNSIKSLEAIGNTRENIDLFRKPIDGSLNEFYGINKRLHEILQQINEQEISNDDTVYSINNLDLWLKEIDQRIKNIGSLSLDPKYINEQERLIQTILAEISSRQPFLENVLMNNASRNEPKLKELDDKIKQKLLVASNIEAKVNDTRKLLGSFEVAVKSCGDWIALTTELLSDRMFVRLDNEKFKEKLDEIKEGYEMKQRDMEQARKICKELVSQSNCKDQNSIEICMENLEKVWSSLNELINTRSKELSDRKNYSEKYAQLKAKIIENLNNWEQTLSMNSPLAIDLLALENQHEDIEYFINEWNSSKPVINEFYKIGSEYDSIMQGFPLGGDQQAKLTSPQRKPSKIKAELYTQPLSPTSITKQPTTANRQSGHYSGSESSGVSSADYVNLNQEFSETILEINDIKSRYSEIGDQLVNRKSDIAALLNKCLSFDQEYKEFSDKLDSELNELLSVEVKNLILNDEIIEIERIDEDIRNLRPTLTNILTMGQDLLRNRELVPGGVELKSKLDRLEKKFISLKDSAKKHLNLRRNTDSQMKKFGEMKKSIENNIVRKERMLNVLGPVGTSVSYGNAQLQQVNALIDEVEGLENDVKELRNIGQEIIRSMSPTSSEVDEIEETLDRLSKKVDNLNKLLKDRELNIHSIMGPSKDFYKLINDVSDRLAVLQEKIDKNDTNVLTSFDWEEIQTELDSIKSILKESENLSKTLLESISDENTHYEIKNKVSNLSRNCREIQWKIDHSVDMIGKRSHHEDVLLTKLEDTEQWLQRKQEQLNLLSLEVGEIPTTLSDNIRQIQILQGDIKHKKSQVEDIYTELNRMNEEKSPTHKSKQIFDKLAVLTNVIENIDTDINNLSIVYQQASTDLNKINNETNKIEAWIDIEKHKMNKHYPVGLESIDSEIKLLECTGKSIENKHQQINDLKNLISPLDVLDSKTLLSKKLSSVFKVESDLKDLKLEADEKLEFLKKLQEQISTTTENMNYLKSALLKLETKAEEYLKFAESADKQPIDVSKLESEIKTTQSDMHLIKPDMENTKLLIASIAQISPVNATLLEPEMEKIVNRYQVLSSSLAQKLIYLNSKHKAMDECKSRIEIFATRQKNLREKIDNFPQSSLDLDSLEDQIHDLANLRRESNEIEKSLSNLKSEVENLAEQKIETAEKSMHKIDNLAAINEKIIESIDDRQNSLILQHKIVTEFESKKNDFIRKIDEANNDPELAKLLNNTSKNIGAFSEQKVDPLKKQLEELIDIGNKACSTVISGLGFKHMEQEMDSVKHSFDRLMQIVSDIENHVDIKLMKEQKFDTSLENLKEFVENISRDLDAEEEPSIEYHKSKSQLNSHRLLLDRLKKRQSSLDELNKAGSDLLINTKEPKKSQLQNELDELNAKYENLLNLAEGKNCRYDRAVKLSKSFKDFYEPSLIWLDTAEKNLANFDTSPTVDAIEMEKRIQEYKHLQNDDSSIDESIKKLKIIINKVDGVFSENVSIDTKNKINKLFDRFSEYQKSHYEKLELLLKFGNLLRNYLDQVNLFEDTLYGFESAMKDLKLNIVDPYQTRDIWEESLNLVKEVKSHEETLKNLDQVGEDLKQISSENDSAAINCKINILHNYFDEISVSALKKLSLFENSIPIAERFLLANNKLDLVLPSLTALVRENDSLTGQVGERNMEILENETNSVEKLVCQARNDLDKLKSVDAFENSLEKVEDIFVENEKRFKEVLNEVTKKATKIGSNRTKAKIQEENLDQCMEVLSNFEQKINEMSDQINNDYSELEECKIDFTNLLSAWNEQKESINSTINDSKKLIRQAPGSDLKSLKSAVDRVKKQSESTTKALESQQQQLDEAIPLAKEFISSYNTLKDWLVETEENMYQNKINNLDPDQLHKAEQEIKALANSWEDQKPLLDIIIKSGHPLSQIVNRVQGKNILANIEDAKKRYNNIKEFIKTRATDLEDLILINTELNEKVDQCANQLENIRDRITDSYQPSVHPEKLDEELGVFDEILYDLDKLQIFVDKLQIGIENCSPSRKNANDKDDSVEISDSILLTIRLKENFLEKLAKISSSNKGLQSQTMEYKEKIMNLLSLANEFWNDLKLIEDKFHEMTIHLTNSTIEDLNTRSVNDKKKLIEDLRGEIDVHEKDIGKISQKGKQLIEKVNNPNETPDVEQAEEELKRNFEAVRSSCEQQITNIDRQQSLITKLEEMRMKLDEWFKEVNNRLFILGPLPTETRPVLTQIQKTKELKNDIEPKHRDIELINQLGYQLTKGSHPNIKNQVNSTLARINDSWARLLDGLGQRQHQLQCILLSLGEFHRAVDEFIEWIIATENSLTNIKIEHGDINSLEMGLAQHKMIRADMNISQASVSKMERKAAEIIKEDVSSLGHEATQRLEQLRKSWEELKEHARAKHFELEDALKEALIFYGDQQEISKNIDELGSKLEMFKFSGGLPDTAKEQLKRFMDIYRTFPKLNIKIEKFIEESAEISKKSSQSIGKAIEIDMEILVKKWDTVKNLAETRKSRLEKAIETVETFHLDMGKFINWLTLTEKNLNQQRPVSRIVSTILEQVEAHRALKRDITSHREEMLNLDKMATHLKYISQKHDIVLIRNLMSSIHHRWEKVVSRSSERSRNLDYGYKEAKRFEDMNRTLLDDIASNLEILERDTSIGQTPSKIREQITKHKEFHCNLGVHNLTYDSTRRLGYQLRDKAPIQDSKKIDEIVHNLQMKWQSLCNKSIEREKALNDALLLSGNYKDAMTNLLSWLRAIEPKLSDSSKRCGGDMNTVQTLLNEHSILEKQLRDRDHMIEKINTDAMALMIQSEEDSSFIEDQLAELKSTWNNVNKLANEKKRRLEEAKNQAIEFERLWNSLKEFFSKSEHELRQFTISPEEEKEELISNMISNHGIFHKNLLMNEMKINDFQQFGHEILVSAYPEAEGSIKHYINIIKSQWSDLLSWSEQRGLNLKDHLDRLNERKILLDDLLLWLAAAEGTLLASESRELSYALAEAKFQYNEHERFITDMTLKQKDHDEIITNSKKKTPPLIPIFDRSKRMETNQGISKIQEPLFVNPKINQLHSKWKQVWFMILNRRKRLLDHIEYLKEVENMKNFNFEDWRRRYMSWMNHSKSRVMDFFRRQDTDHDGRVTRKEFIDGIIDSKFQTTRVEMEVVADIFDKEKSGFIDYRQFLAALRPDRETYQVKPANENEIIHDEVKKQISKCTCSNPYKITQCGDGKYKFGDTEKLRLVRILRSNVMVRIGGGWCALDEFLVKHDPCREA------CVPEPSNDTESIKNSKGRTNYELREKLSNPKGTINTMAPFKFKPATLPIPTKKPTTAKIPSPRVSQPLSSPRIHQPVSSPRIPQPVTSPRISQNIPSSRVSQSLASPRTPKVVASPGLQRKSRIPTRQTSQQGSQASTRHQSRDISPETVTSTNKQMNE 8308 HSP 2 Score: 108.227 bits (269), Expect = 3.136e-22 Identity = 238/1104 (21.56%), Postives = 452/1104 (40.94%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG-----LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAYE-NKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKII-TEN------QYNRIVFLTCPLIKFSISIDEIAIN----IDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLTEKLEIKLPTINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRD-NCGHIITLNDAIN------------------------EDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNY--------FGDDQDSKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTS--NITSLTGSNTEN----------------------------------NSTQLFIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG---LIVNEGDSERLE-EKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L+T N K +DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E + K IS L K +++ T+ ++ LT+ +A+ + L+D G I D + + IS+ E II EN + + V L+ ++K +I + N ID+ E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT + E + + + + + +TL+EA+ +D R ++ P +G+ I L+EAI + D I D G ++L++ + E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D + L+ T++ +IR P+S A+ R ++ +A K +S +E L S NI++L S E ++ + I +P +G++++L+EAI I D + I S S E +K G ++ + ER++ EK + + Y + + ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 406 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLT-NEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYS-TDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLS-EMLKSGKNISALLTNEKERIDK------EKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLNSGKNISALLTSEKE-------RMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLR-GTIRD--PISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTL-----DEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 1412 HSP 3 Score: 107.071 bits (266), Expect = 5.872e-22 Identity = 226/1079 (20.95%), Postives = 435/1079 (40.32%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKEAY------------ENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEG----DSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + I K +L + + LT+ A+ + L+D G I D + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS SV KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ I + + I E + E+ TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I E D+E+ +++I + + ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ ++ + + T+ TL +A++ GL+ T+ T Sbjct: 887 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISSLLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKQTKLEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQKRIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 1885 HSP 4 Score: 102.834 bits (255), Expect = 1.242e-20 Identity = 233/1097 (21.24%), Postives = 451/1097 (41.11%), Query Frame = 3 Query: 5055 DPITNTELKYTDAIRYQYINDDISEILFVDPSEN-------------SFHLTTKEAVKNKFFDPESGNI-FDHNRDS-YIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG----LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISG----PNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI---AINIDQ---TECNLFENRKL--YQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 DPI+ TE+ +AI I+ + S I + ++ S LT+++ +K E I +++ D+ ++ L A ++G++ ++ + E S+ EA+ RGIID + Q +SL E +++G ++ N K +DK K + +S + + ++ L+E++ G I P +++L AI GIID +N + + SL E E + + K +L + + LT+ +A+ + L+D G I D + + IS+ E II + N ++ S+S+ E+ NI +E + KL + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS SV KE + + E ++ +S Y + ++EA+ G ++ + + +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T+++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ I + + I E + E+ TD + +T ++A+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E N +Y+ KG V+ ++ML + I+ L+ K + LE S+ + T + E + K + +++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 1962 DPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEI-----------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISVLQTNEKERIDKEKQTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTI------------RDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG--KNISALLTNEKERIDKEKQTELEKISMEY-STDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAE---------NSAIYD---AEKGQSVS---LSEMLKSGK--NISALLTSEKERMDKEKLTELEKISMEYS--TDAHHLTLDEAMEKGLVDTLRVTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 2995 HSP 5 Score: 100.908 bits (250), Expect = 5.018e-20 Identity = 241/1105 (21.81%), Postives = 439/1105 (39.73%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISG---PNQEIIHPNLTQK-LTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKII---------TENQYNRI---VFLTCPLIKFSISIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANF-IQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDV--------KSLNNELKIIGF---------------------------KDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNE----AEDLGFVLT--------------EKLEIKLPT------INDLITQGLVDFDSGIV--TLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEFVPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQLIKDPKTG--KSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++G L +E ++ DK K + +S + + ++ L+E++ G + I ++ K ++L AI GIID +N + + SL E E + + K L +L + + LT+ +A+ + L+D G I D + + IS+ E II E RI I S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + I KER+ + K + EKI + + ++ +A+E G++D L G I D +I + EAI G I+A + + K EL+ I +DPISG IS +AI +G++D + ++ + Q ++++E +++ +LT EK+ ++ T +++ + +GLVD G + T+ +E+S L EAI ID + S + + G+ + L E +++ + ++ N I + TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E N +Y+ KG V+ ++ML + + Q + + K T L S A +TL E + K + ++ DP + I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 1481 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGTEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERM--DKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQKRIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT---IRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQNKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEIS--LQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISV---LQTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGII----DAE---------NSAIYD---AEKGQSVS---LSEMLKSGKNISVLQTNEKERIDKEKQTELEKISMEYSTDAHHLTLD------EAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 2500 HSP 6 Score: 99.3673 bits (246), Expect = 1.313e-19 Identity = 231/1112 (20.77%), Postives = 435/1112 (39.12%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISIL------------QIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNE------QFSLKEAYENKFISKSLLKDLTVYCGITNG-NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKG-----LVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQMLTENQIDPINQL------IKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYDPRINQLITYQEAIDRQVINIIDSTYINHKTNEISTLSDALQHG 8066 ++ +EA+ D E+ I+D + + L + G K IS L Q LEK + D ++ ++ EA+ +G++D P ++ISL E + G++ I D K + L+E L SG N + N ++ ID + + + I+ E +L EA E + T+ I + + +++++ +AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ +A+E G++D L G I D +I + EAI G I+A + D G +S + ++ G L+ +K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ NS +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LTN+ + +ID Q ++ TL + +E G V TL ++ DP I+ QEAI R +I+ +S + + + +LS+ L+ G Sbjct: 149 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKQTELEKISMEYSTDAHH--LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEEIARGIIDAENSAIYDAEKGQ----------SVSLSEMLKSGKNISALLTNEKER-----------IDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD-------TLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDEAMEKGLVDTLRGT---IRDPISGKEISLQEAIARGIIDAENS------------AIYDAEKGQSVSLSEMLKSGKNISALLTKKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLNSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHHLTLDDAMEKGLVD----TLRG------------------TIRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG 1161 HSP 7 Score: 99.3673 bits (246), Expect = 1.500e-19 Identity = 213/1021 (20.86%), Postives = 403/1021 (39.47%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQN-----GLVTENGKIIVDKNKPS----LSFLDAFNKGYIKLNESLISGP----NQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNEQFSLKE------------AYENKFISKSLLKDLTVYCGITNGNNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLTCPLIKFSISIDEI--------AINIDQTECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDANFIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDRKFENFWNTKSNQILTMNEAEDLGFVLTEKLEI-KLP----------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSNSIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDNCGHIITLNDAINEDLFPEF------VPTDKNKITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQLFIIN---PNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMGLIVNEGDSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLTNQ---MLTENQ---------------------------IDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLY 7883 E + ++ S ++ HLT EA++ D G I D PIS +I S+ EA+ RGIID + Q +SL E +++ L+T K +DK K + +S + + ++ L+E++ G I P ++++L AI GIID +N + + SL E E + + K L +L + + LT+ +A+ + L+D G I D + + IS+ E II + N ++ S+S+ E+ A+ + E E + + I+ Y S +++LDEA ++ ++ G S +AI I N + SE +KS S KE + + E ++ +S Y + ++EA+ G ++ + ++ DPISG IS +AI +G++D + ++ + Q ++++E G + ++ E+ K+ T+++ + +GLVD G + P ++L EAI ID + S + + G+ + L E +++ ++ + + + ++++ E TD + +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + NE++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I+ L L+EA+++ + D + IR + S +E++ G+I D+E ++ V + G ++A LT++ M E Q +D + I+DP +GK +L + G II N ++Y Sbjct: 3315 EKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRD--------------------PISGKEI------------------SLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSDKNISALLTSE-KERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII--DAENSAIYDAEK--GQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEY-STDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTE---LEKISMEYSTDAHH-----LTLDEAMEKGLVDTLRGTIR------------DPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNIKKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---------KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNEKERIDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGII----DAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQSELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY 4252 HSP 8 Score: 98.9821 bits (245), Expect = 1.896e-19 Identity = 243/1158 (20.98%), Postives = 462/1158 (39.90%), Query Frame = 3 Query: 5166 LTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIV----LEKDEFPFLVDINNEKSS------ISEALVRGIIDGNSEFSIKPNFSQK-ISLFEAVQNGLVTENGKIIVDKNKPSLSFLDAFNKGYIKLNESLISGPNQEIIHPNLTQKLTLLGAIQLGIIDTKNEKFINTITNE------QFSLKEAYENKFISKSLLKDLTVYCGITNG-NNEKLTILQAINENLIDIKTGQIFDRSNNQFISINEGYYDKIITENQYNRIVFLT-----------CPLIKFSI--SIDEIAINIDQT-ECNLFENRKLYQTITTVYDSKQNEYISLDEARKRDFINDDMGMYYHEKDRIYYSFTDAIDAN----FIQTNNEKSKERVXXXXXXXXXXXXXXXXXXVFNPITKEWVSARQAVEDGIIDHLSGNYKIINDFGFVIDIPINEAILSGYIEAIDEDVKSLNNELKIIGFKDPISGGIISPIDAIEKGLVDR-------KFENFWNTKSNQILTMNEAEDLGFVLTEKLEIKLP------TINDLITQGLVDFDSGIVTLPNREVSMTLNEAINSN------------------SIDIDRSMLKHPDNGRHICLREAIENDLFDPIRCEIRDN-CGHIITLNDAINEDL------------------FPEFVPTDKN--------------------------------KITFEEALEQGYIDLKTNTFRDPRNDNVYGVEEALAKNILDHPQSNV-------TVYMTDVQNSVQNKTLEIPNEEKFVDTKTTKTLESIKRNYFGDDQD------------SKLIQTVKDASIRQELPLSVATDERITAVNRKPSNSMENAHSLGLKSPKLSTNESLTSNITSLTGSNTENNSTQL------------------------------FIINPNTGRKLNLEEAIKENIYDPVENMIRSVTNNNSYSWEESVKMG-----LIVNEG---DSERLEEKIIQRNCVVYNYYYVHKGVGVTAKLT-NQMLTENQIDPINQLIKDPKTGKSTTLINGLENGSVFATIITLTNRSLYFENLNKRHDNYQIISVYD-----PRINQLITYQ-EAIDRQVINIIDSTYINHKTNEIS-TLSDALQHGLLHTIMKT 8090 ++ +EA+ D E+ I+D + + L + G K IS L ++K++ L I+ E S+ + EA+ +G++D +I+ S K ISL EA+ G++ I D K + L+E L SG N ++ N ++ ID + + + I+ E +L EA E + T+ I + + +++++ +AI +ID + I+D Q +S++E + ++ N LT L K S+ S D + +D+ E L + + T+ D + ISL EA R I+ + Y + S ++ + + + TN KER+ + K + EKI + + ++ A+E G++D L G I D +I + EAI G I+A + + + + SG IS + EK +D+ K ++T ++ LT++EA + G V T + I+ P ++ + I +G++D ++ + + S++L+E + S ++++ +++ + H+ L EA+E L D +R IRD G I+L +AI + E + + KN +T +EA+E+G +D T RDP + ++EA+A+ I+D S + +V ++++ S +N + + +E++ +D + LE I Y D L T++D +E+ L A I E S+ L S L + +++++ +TS + T+L I +P +G++++L+EAI I D + I S S E +K G L+ +E D E+L E +++ + Y+ H LT ++ + + +D + I+DP +GK +L + G II N ++Y + Q +S+ + I+ L+T + E +D++ + ++ + + T+ TL +A++ GL+ T+ T Sbjct: 2266 ISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSG---KNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVD-TLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQ----------SVSLSEMLKSGKNISVLQTNEKER-----------IDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVD-------TLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSE------MLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLR-----GTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTNE---KERIDKEKQTELEKISMEYSTDAHH------LTLDDAMEKGLVDTLRGT---IRDPISGTEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHH-LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRVTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKQTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDTISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSL-SEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARGIIDAENSAIYDAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTE--LEKISMEYSTDAHH--------LTLDEAMEKGLVDTLRGTIRDPISGKEISLQEAIARG-----IIDAENSAIY------DAEKGQSVSLSEMLKSGKNISALLTSEKERMDKEKLTELEKISMEYSTDAHHLTLDEAMEKGLVDTLRGT 3345 HSP 9 Score: 98.2117 bits (243), Expect = 2.627e-19 Identity = 248/1195 (20.75%), Postives = 466/1195 (39.00%), Query Frame = 3 Query: 5127 EILFVDPSENSFHLTTKEAVKNKFFDPESGNIFDHNRDSYIPLHYARQEGILSKPISILQIVLEKDEFPFLVDINNEKSSISEALVRGIIDGNSEFSIKPNFSQKISLFEAVQNG------LVTENGKIIVDKNKPS |