Family with sequence similarity 227 member B

Overview
NameFamily with sequence similarity 227 member B
Smed IDSMED30002718
Length (bp)1430
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Family with sequence similarity 227 member B (SMED30002718) t-SNE clustered cells

Violin plots show distribution of expression levels for Family with sequence similarity 227 member B (SMED30002718) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30002718

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30002718SMESG000052176.1 SMESG000046302.1 SmedASXL_016775SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30002718SMESG000052176.1 SMESG000046302.1 dd_Smed_v4_15102_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30002718SMESG000052176.1 SMESG000046302.1 dd_Smed_v4_15102_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30002718SMESG000052176.1 SMESG000046302.1 dd_Smed_v4_15102_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30002718SMESG000052176.1 SMESG000046302.1 dd_Smed_v4_15102_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30002718SMESG000052176.1 SMESG000046302.1 dd_Smed_v4_15102_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
parapharyngeal regionSMED30002718SMESG000052176.1 SMESG000046302.1 dd_Smed_v4_15102_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30002718SMESG000052176.1 SMESG000046302.1 dd_Smed_v4_15102_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30002718SMESG000052176.1 SMESG000046302.1 dd_Smed_v4_15102_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30002718SMESG000052176.1 SMESG000046302.1 dd_Smed_v6_15102_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Human
Match: FAM227B (family with sequence similarity 227 member B [Source:HGNC Symbol;Acc:HGNC:26543])

HSP 1 Score: 111.309 bits (277), Expect = 1.114e-25
Identity = 90/277 (32.49%), Postives = 130/277 (46.93%), Query Frame = 2 
Query:  461 DNKALPKLIELCQHPGFNWIKITELPFSVQPE----FILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPT---------EQKLKEKAIEEQLRIGFS-DLQIEK--KTPEKDQLKNS--------VSTKSTLLGALNHSNNVLFNVSGHSPLIQWFLERNSL 1219
            D     K IE C   GF   ++T+LP  +  E    FILK  H      F KI+K  F      +    LL D FW+ F+ K+  D + +D    F R SESYV     I + +   ++ F ++ P+ L+QA+Y    E FP+S   FN++F E++   +F W SG++P KG W  W ++EL  T          + +KE+  + Q  I  S D  I K    P    L  S        ++TKS         N VLFN  G SPLI ++L+ + L
Sbjct:  138 DEMETEKNIEGCSFTGFKANELTQLPRHLDAEQIYLFILK-AHNFDERVF-KIWKTHF----LSEASIALLHDSFWWWFLHKFRPDRENQDC--LFDRISESYVTLFMSIPLSR---KDAFFQIYPDCLAQAIYATFHEAFPESSYLFNDEFKEDLGNNIFLWCSGLKPQKGFWIHWKLKELSTTTIHGSKKAPAKSVKERIADSQEHISTSIDFNIIKILNNPRAYTLPISKEESRLSRLATKSHYSSTGPEFNRVLFNFGGQSPLILYYLKMHEL 403
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Human
Match: FAM227A (family with sequence similarity 227 member A [Source:HGNC Symbol;Acc:HGNC:44197])

HSP 1 Score: 78.9518 bits (193), Expect = 5.352e-15
Identity = 79/336 (23.51%), Postives = 150/336 (44.64%), Query Frame = 2 
Query:   32 YFKMNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYS--IGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKALPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYC--QKIQDLLK---------DMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKP 1000
            + KM  +N    PM P+DE+L  + + R   ++ ++ +EL  +P S  IGS+  +  KI+ +  + +     ++ E  + ++        +  +  +  +++ +   K + +    S+V       IK+                 +K L  L EL Q+  FN  K  +LP  V    ++  V        ++  ++      +C  ++++  L          D FW+IF  +Y    +K+  +N F R ++ Y   LF++   K + +E   K LP+LLS+A+Y +   CFP SW    ++F  +I   +  W+SG  P+  S+  W+  EL P
Sbjct:    4 FRKMEVINLTTLPMIPVDEHLAVSLVARNTMVKTVR-KELENNPPSCLIGSMHQVNQKIADINLRTEPSANSLAIERFELEKKALREKTRSSPEDKVKRQRKSQYSCKGSELRHARSSV-------IKRKTA--------------DKNL--LAELYQYSNFNSSKPNKLPNGVDFCDMVGNV--------VRAERDCLSGKHFCSGRELEKFLSSSSPRAIWLDSFWWIFHERY--QPNKELQNNLFDRIAQHYALLLFRVP--KSHSEEALLKRLPSLLSKAVYTSFCCCFPQSWFD-THEFKSDICNTMSLWISGTYPSPQSYDSWDYSELDP 302
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Human
Match: FAM227A (family with sequence similarity 227 member A [Source:HGNC Symbol;Acc:HGNC:44197])

HSP 1 Score: 78.9518 bits (193), Expect = 5.985e-15
Identity = 79/336 (23.51%), Postives = 150/336 (44.64%), Query Frame = 2 
Query:   32 YFKMNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYS--IGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKALPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYC--QKIQDLLK---------DMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKP 1000
            + KM  +N    PM P+DE+L  + + R   ++ ++ +EL  +P S  IGS+  +  KI+ +  + +     ++ E  + ++        +  +  +  +++ +   K + +    S+V       IK+                 +K L  L EL Q+  FN  K  +LP  V    ++  V        ++  ++      +C  ++++  L          D FW+IF  +Y    +K+  +N F R ++ Y   LF++   K + +E   K LP+LLS+A+Y +   CFP SW    ++F  +I   +  W+SG  P+  S+  W+  EL P
Sbjct:    4 FRKMEVINLTTLPMIPVDEHLAVSLVARNTMVKTVR-KELENNPPSCLIGSMHQVNQKIADINLRTEPSANSLAIERFELEKKALREKTRSSPEDKVKRQRKSQYSCKGSELRHARSSV-------IKRKTA--------------DKNL--LAELYQYSNFNSSKPNKLPNGVDFCDMVGNV--------VRAERDCLSGKHFCSGRELEKFLSSSSPRAIWLDSFWWIFHERY--QPNKELQNNLFDRIAQHYALLLFRVP--KSHSEEALLKRLPSLLSKAVYTSFCCCFPQSWFD-THEFKSDICNTMSLWISGTYPSPQSYDSWDYSELDP 302
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Human
Match: FAM227A (family with sequence similarity 227 member A [Source:HGNC Symbol;Acc:HGNC:44197])

HSP 1 Score: 78.5666 bits (192), Expect = 6.878e-15
Identity = 81/338 (23.96%), Postives = 152/338 (44.97%), Query Frame = 2 
Query:   32 YFKMNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYS--IGSVIDIENKISKLEEQIKGFETKISWE--DIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKALPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYC--QKIQDLLK---------DMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKP 1000
            + KM  +N    PM P+DE+L  + + R   ++ ++ +EL  +P S  IGS+  +  KI+ +  + +     ++ E  +++   + +   +  + +V    K+++K      G     S +   +   IK+                 +K L  L EL Q+  FN  K  +LP  V    ++  V        ++  ++      +C  ++++  L          D FW+IF  +Y    +K+  +N F R ++ Y   LF++   K + +E   K LP+LLS+A+Y +   CFP SW    ++F  +I   +  W+SG  P+  S+  W+  EL P
Sbjct:    4 FRKMEVINLTTLPMIPVDEHLAVSLVARNTMVKTVR-KELENNPPSCLIGSMHQVNQKIADINLRTEPSANSLAIERFELEKKALREKTRSSPEDKV----KRQRKSQYSCKG-----SELRHARSSVIKRKTA--------------DKNL--LAELYQYSNFNSSKPNKLPNGVDFCDMVGNV--------VRAERDCLSGKHFCSGRELEKFLSSSSPRAIWLDSFWWIFHERY--QPNKELQNNLFDRIAQHYALLLFRVP--KSHSEEALLKRLPSLLSKAVYTSFCCCFPQSWFD-THEFKSDICNTMSLWISGTYPSPQSYDSWDYSELDP 302
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Human
Match: FAM227B (family with sequence similarity 227 member B [Source:HGNC Symbol;Acc:HGNC:26543])

HSP 1 Score: 70.0922 bits (170), Expect = 1.337e-12
Identity = 57/206 (27.67%), Postives = 86/206 (41.75%), Query Frame = 2 
Query:  461 DNKALPKLIELCQHPGFNWIKITELPFSVQPE----FILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQ 1066
            D     K IE C   GF   ++T+LP  +  E    FILK  H      F KI+K  F      +    LL D FW+ F+ K+                                       ++ P+ L+QA+Y    E FP+S   FN++F E++   +F W SG++P KG W  W ++EL  T     +KA  + ++   +D Q
Sbjct:  138 DEMETEKNIEGCSFTGFKANELTQLPRHLDAEQIYLFILK-AHNFDERVF-KIWKTHF----LSEASIALLHDSFWWWFLHKF---------------------------------------RIYPDCLAQAIYATFHEAFPESSYLFNDEFKEDLGNNIFLWCSGLKPQKGFWIHWKLKELSTTTIHGSKKAPAKSVKERIADSQ 298
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Xenopus
Match: ENSXETT00000000957.1 (family with sequence similarity 227 member A [Source:NCBI gene;Acc:100495201])

HSP 1 Score: 113.62 bits (283), Expect = 1.223e-26
Identity = 110/413 (26.63%), Postives = 195/413 (47.22%), Query Frame = 2 
Query:   41 MNTLNRFCSPMHPMDENLDDT--DIIREKKIEFIKLRELTKSP--YSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDE----VVDNGGNDNQIQVNLN-IKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKALPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYK-EFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQF-NNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKL--KEKAI------EEQLRIGF---SDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWFLERN 1213
            M+ +NR    M P +E L     DI + K+      +E+T+SP  + IGS+  +  +I+ L+ +      K + ED+ S      V D  G   + +   N I+ E+K +EKF   +  +      + + I K +                K+ P+++EL Q  G +    T LP+ +  + I+ RV  +   T  KI   +   +       ++++ D FW+I++ KY  D + +     F R +E+Y+  L  +T ++ ++ E F KV P++LSQA+Y +    FP S  +F  +DF   +  L++ W+ GI P+ G +  W+   L+P    +  K+K +      E + + GF   +  +I + T E        S  +    A  H    LF++SGHSPL+Q++L+ N
Sbjct:    1 MDWINRLSCSMAPYEEELTKGYLDIYQSKES---ARKEITESPACFLIGSIESVNQRIAHLDMKT----NKCNSEDLGSRGFSSLVYDAQGKPLKAEQKQNKIESEQKVLEKFTHRYEHLFLEHHQETQDIGKKML---------------KSTPRMVELYQFSGRSDAGPTPLPYGIALDTIIDRVVSAHENTGGKICSPKEVRRNLSSLVTKEMILDCFWWIYLHKYKPDTECQ--KQLFDRVAENYIKLL-GVTFDQ-HHGEAFLKVFPSVLSQAIYSSFCFSFPQSLYRFQTDDFRTQLCNLLWQWIGGISPSPGCYKTWDFHILEPEVDMVHGKQKQVSDIINGEGKTQGGFVTSTQTRIHRVTKE--------SHPACCGPAFTHK---LFSLSGHSPLVQYYLQEN 376
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Xenopus
Match: ENSXETT00000055522.1 (family with sequence similarity 227 member B [Source:NCBI gene;Acc:101733874])

HSP 1 Score: 94.3597 bits (233), Expect = 2.660e-20
Identity = 74/266 (27.82%), Postives = 126/266 (47.37%), Query Frame = 2 
Query:  485 IELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTF--IKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTE----------------QKLKEKAIEEQLRIGFSDL-QIEKKTPEKD--QLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWFLERNSL 1219
            +E C    F   +  +LP  V+   IL  V ++Q +    +K  K+FF      +    +L+D FW+    ++  D    D +  F R S S+    + +       ++ F K+ P+ LSQA++    E FP+S + FN+ F   +M L+F W+SG++P   SW+ W++  L+ T                  K  +K  E QL     DL Q  ++T      ++K+  +T+S  +G     ++VLF + GHSPLI  +L+ + L
Sbjct:  128 VENCVLTIFKSNECIKLPGCVEAAQILNLVTKAQNIKGDNLKAMKKFF----LSEASVAVLQDSFWWFLCQQFKPD--HADQNYLFDRISASFTNLFWSVPHN---VKDFFFKIYPDCLSQAIFAVFYEAFPESRVLFNDKFKSEVMDLIFQWVSGVKPAPCSWAHWDLSLLERTNLNVDKIHNNLTKNDETHKSLQKNGEWQLNFNLDDLIQKARETYHSSVHEVKDVHATESHCIGPGPEFHHVLFKLGGHSPLISNYLKMHKL 384
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Mouse
Match: Fam227b (family with sequence similarity 227, member B [Source:MGI Symbol;Acc:MGI:1923073])

HSP 1 Score: 107.842 bits (268), Expect = 1.219e-24
Identity = 70/208 (33.65%), Postives = 108/208 (51.92%), Query Frame = 2 
Query:  656 LLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPT--------EQKLKEKAIEEQLRI-GFSDLQIEK--KTPE--------KDQLKNSVSTKSTLLGALNHS-NNVLFNVSGHSPLIQWFLERNSL 1219
            LL D FW+ F+ K+  D  K+D    F R +ESYV    KI + +   ++ F K+ P+ L+QA+Y    E FP+S   FN+ F E++   +F WLSG++P  G W+ W +++L  T          KL+   I  Q  I G  DL+IE   K P         K+ + +  +TK +   +L    + VLF+  G SPLI ++L+ + L
Sbjct:  190 LLHDSFWWWFLHKFKPD--KRDEDFLFDRIAESYVTLFIKIPLRR---KDAFFKMYPDCLTQAVYTTFQESFPESCSLFNDKFKEDLGNTIFLWLSGLKPETGFWTHWKLQDLCTTTIHGSRRVPVKLRRSVIPSQEHIPGIRDLKIEDILKNPRAYAMPKLMKESVASKAATKPSHYRSLGPEFHKVLFDFGGQSPLILYYLKMHEL 392
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Mouse
Match: Fam227b (family with sequence similarity 227, member B [Source:MGI Symbol;Acc:MGI:1923073])

HSP 1 Score: 107.842 bits (268), Expect = 1.375e-24
Identity = 70/208 (33.65%), Postives = 108/208 (51.92%), Query Frame = 2 
Query:  656 LLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPT--------EQKLKEKAIEEQLRI-GFSDLQIEK--KTPE--------KDQLKNSVSTKSTLLGALNHS-NNVLFNVSGHSPLIQWFLERNSL 1219
            LL D FW+ F+ K+  D  K+D    F R +ESYV    KI + +   ++ F K+ P+ L+QA+Y    E FP+S   FN+ F E++   +F WLSG++P  G W+ W +++L  T          KL+   I  Q  I G  DL+IE   K P         K+ + +  +TK +   +L    + VLF+  G SPLI ++L+ + L
Sbjct:  190 LLHDSFWWWFLHKFKPD--KRDEDFLFDRIAESYVTLFIKIPLRR---KDAFFKMYPDCLTQAVYTTFQESFPESCSLFNDKFKEDLGNTIFLWLSGLKPETGFWTHWKLQDLCTTTIHGSRRVPVKLRRSVIPSQEHIPGIRDLKIEDILKNPRAYAMPKLMKESVASKAATKPSHYRSLGPEFHKVLFDFGGQSPLILYYLKMHEL 392
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Mouse
Match: Fam227b (family with sequence similarity 227, member B [Source:MGI Symbol;Acc:MGI:1923073])

HSP 1 Score: 107.842 bits (268), Expect = 1.375e-24
Identity = 70/208 (33.65%), Postives = 108/208 (51.92%), Query Frame = 2 
Query:  656 LLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPT--------EQKLKEKAIEEQLRI-GFSDLQIEK--KTPE--------KDQLKNSVSTKSTLLGALNHS-NNVLFNVSGHSPLIQWFLERNSL 1219
            LL D FW+ F+ K+  D  K+D    F R +ESYV    KI + +   ++ F K+ P+ L+QA+Y    E FP+S   FN+ F E++   +F WLSG++P  G W+ W +++L  T          KL+   I  Q  I G  DL+IE   K P         K+ + +  +TK +   +L    + VLF+  G SPLI ++L+ + L
Sbjct:  190 LLHDSFWWWFLHKFKPD--KRDEDFLFDRIAESYVTLFIKIPLRR---KDAFFKMYPDCLTQAVYTTFQESFPESCSLFNDKFKEDLGNTIFLWLSGLKPETGFWTHWKLQDLCTTTIHGSRRVPVKLRRSVIPSQEHIPGIRDLKIEDILKNPRAYAMPKLMKESVASKAATKPSHYRSLGPEFHKVLFDFGGQSPLILYYLKMHEL 392
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Mouse
Match: Fam227a (family with sequence similarity 227, member A [Source:MGI Symbol;Acc:MGI:1922979])

HSP 1 Score: 70.4774 bits (171), Expect = 1.960e-12
Identity = 55/176 (31.25%), Postives = 87/176 (49.43%), Query Frame = 2 
Query:  482 LIELCQHPGFNWIKITELPFSVQPEFILKRV--HESQPLTFIKIYKEFFDKWFYCQK-IQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKP 1000
            L EL +HP F+ +K  +LP  V    ++  V   E  PL+      +   + F C   +  +  D FW++F  +Y    DK+     F R + +Y   LFK  M + +Y+E   K L +LLS+A+Y +   CFP SW    ++F   I   +  W+SG+ P   S++ W+  EL P
Sbjct:  127 LAELHEHPPFDEMKPNKLPNGVDFCDMVGNVIRSEKNPLSGKSYCSDRELEKFLCSPFLAAMWLDSFWWLFHERY--QPDKEIQKKLFDRIARNYASLLFK--MCRSHYEEALLKRLSSLLSKAMYTSFCCCFPQSWFN-THEFKSEICNTMNLWVSGMYPCLQSYNNWDYSELDP 297
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Mouse
Match: Fam227a (family with sequence similarity 227, member A [Source:MGI Symbol;Acc:MGI:1922979])

HSP 1 Score: 70.4774 bits (171), Expect = 1.969e-12
Identity = 55/176 (31.25%), Postives = 87/176 (49.43%), Query Frame = 2 
Query:  482 LIELCQHPGFNWIKITELPFSVQPEFILKRV--HESQPLTFIKIYKEFFDKWFYCQK-IQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKP 1000
            L EL +HP F+ +K  +LP  V    ++  V   E  PL+      +   + F C   +  +  D FW++F  +Y    DK+     F R + +Y   LFK  M + +Y+E   K L +LLS+A+Y +   CFP SW    ++F   I   +  W+SG+ P   S++ W+  EL P
Sbjct:  131 LAELHEHPPFDEMKPNKLPNGVDFCDMVGNVIRSEKNPLSGKSYCSDRELEKFLCSPFLAAMWLDSFWWLFHERY--QPDKEIQKKLFDRIARNYASLLFK--MCRSHYEEALLKRLSSLLSKAMYTSFCCCFPQSWFN-THEFKSEICNTMNLWVSGMYPCLQSYNNWDYSELDP 301
[Close]
BLAST of Family with sequence similarity 227 member B vs. UniProt/SwissProt
Match: sp|Q96M60|F227B_HUMAN (Protein FAM227B OS=Homo sapiens OX=9606 GN=FAM227B PE=2 SV=2)

HSP 1 Score: 111.309 bits (277), Expect = 5.352e-25
Identity = 90/277 (32.49%), Postives = 130/277 (46.93%), Query Frame = 2 
Query:  461 DNKALPKLIELCQHPGFNWIKITELPFSVQPE----FILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPT---------EQKLKEKAIEEQLRIGFS-DLQIEK--KTPEKDQLKNS--------VSTKSTLLGALNHSNNVLFNVSGHSPLIQWFLERNSL 1219
            D     K IE C   GF   ++T+LP  +  E    FILK  H      F KI+K  F      +    LL D FW+ F+ K+  D + +D    F R SESYV     I + +   ++ F ++ P+ L+QA+Y    E FP+S   FN++F E++   +F W SG++P KG W  W ++EL  T          + +KE+  + Q  I  S D  I K    P    L  S        ++TKS         N VLFN  G SPLI ++L+ + L
Sbjct:  138 DEMETEKNIEGCSFTGFKANELTQLPRHLDAEQIYLFILK-AHNFDERVF-KIWKTHF----LSEASIALLHDSFWWWFLHKFRPDRENQDC--LFDRISESYVTLFMSIPLSR---KDAFFQIYPDCLAQAIYATFHEAFPESSYLFNDEFKEDLGNNIFLWCSGLKPQKGFWIHWKLKELSTTTIHGSKKAPAKSVKERIADSQEHISTSIDFNIIKILNNPRAYTLPISKEESRLSRLATKSHYSSTGPEFNRVLFNFGGQSPLILYYLKMHEL 403
[Close]
BLAST of Family with sequence similarity 227 member B vs. UniProt/SwissProt
Match: sp|Q9D518|F227B_MOUSE (Protein FAM227B OS=Mus musculus OX=10090 GN=Fam227b PE=2 SV=3)

HSP 1 Score: 107.842 bits (268), Expect = 9.620e-24
Identity = 70/208 (33.65%), Postives = 108/208 (51.92%), Query Frame = 2 
Query:  656 LLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPT--------EQKLKEKAIEEQLRI-GFSDLQIEK--KTPE--------KDQLKNSVSTKSTLLGALNHS-NNVLFNVSGHSPLIQWFLERNSL 1219
            LL D FW+ F+ K+  D  K+D    F R +ESYV    KI + +   ++ F K+ P+ L+QA+Y    E FP+S   FN+ F E++   +F WLSG++P  G W+ W +++L  T          KL+   I  Q  I G  DL+IE   K P         K+ + +  +TK +   +L    + VLF+  G SPLI ++L+ + L
Sbjct:  190 LLHDSFWWWFLHKFKPD--KRDEDFLFDRIAESYVTLFIKIPLRR---KDAFFKMYPDCLTQAVYTTFQESFPESCSLFNDKFKEDLGNTIFLWLSGLKPETGFWTHWKLQDLCTTTIHGSRRVPVKLRRSVIPSQEHIPGIRDLKIEDILKNPRAYAMPKLMKESVASKAATKPSHYRSLGPEFHKVLFDFGGQSPLILYYLKMHEL 392
[Close]
BLAST of Family with sequence similarity 227 member B vs. UniProt/SwissProt
Match: sp|Q4R7D5|F227B_MACFA (Protein FAM227B OS=Macaca fascicularis OX=9541 GN=FAM227B PE=2 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 9.532e-22
Identity = 68/206 (33.01%), Postives = 104/206 (50.49%), Query Frame = 2 
Query:  461 DNKALPKLIELCQHPGFNWIKITELPFSVQPE----FILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQ 1066
            D     K IE C   GF   ++T+LP  +  E    FILK  H      F KI+K  F      +    LL D FW+ F+ K+  D + +D    F R SESYV     I + +   ++ F ++ P+ L+QA+Y    E FP+S   FN++F E++   +F W SG++P KG W+ W ++EL  T     +KA  + ++   +D Q
Sbjct:  138 DEMETEKNIEGCSFTGFKANELTKLPRHLDAERIYLFILK-AHNFDERVF-KIWKTHF----LSEASIALLHDSFWWWFLHKFRPDRENQDC--LFDRISESYVTLFMSIPLSR---KDAFFQIYPDCLAQAIYATFHEAFPESSYLFNDEFKEDLGNTIFLWCSGLKPQKGFWTHWKLKELSTTTIHGSKKAPAKSVKERIADSQ 332
[Close]
BLAST of Family with sequence similarity 227 member B vs. UniProt/SwissProt
Match: sp|Q6AXP3|F227B_RAT (Protein FAM227B OS=Rattus norvegicus OX=10116 GN=Fam227b PE=2 SV=2)

HSP 1 Score: 96.6709 bits (239), Expect = 4.979e-20
Identity = 64/205 (31.22%), Postives = 105/205 (51.22%), Query Frame = 2 
Query:  656 LLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTE--------QKLKEKAIEEQLRIGFS-DLQIEK--KTP------EKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWFLERNSL 1219
            LL D FW+ F+ K+  D  K+D    F R +ESYV    +I + +   ++ F ++ P+ L+QA+Y    E FP+S   FN++F E++   +F WLSG++P  G W+ W +++L  T          KL+   +  Q     +  L+IE   K P      +++   + V+TKS           VLF+  G SPLI ++L+ + L
Sbjct:  190 LLHDCFWWWFLHKFKPD--KRDQDWLFDRIAESYVTLFMRIPLRR---KDIFFQMYPDWLAQAVYTTFQESFPESCSLFNDNFKEDLGNTIFLWLSGLKPAPGFWTHWKLQDLCTTTIHGCRRVPVKLRRGIMSSQEHTSATVGLKIEDILKNPRALPVLKEESAASKVTTKSHYRSLGPEFYKVLFDFGGQSPLILYYLKMHEL 389
[Close]
BLAST of Family with sequence similarity 227 member B vs. UniProt/SwissProt
Match: sp|F5H4B4|F227A_HUMAN (Protein FAM227A OS=Homo sapiens OX=9606 GN=FAM227A PE=1 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 2.570e-14
Identity = 79/336 (23.51%), Postives = 150/336 (44.64%), Query Frame = 2 
Query:   32 YFKMNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYS--IGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKALPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYC--QKIQDLLK---------DMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKP 1000
            + KM  +N    PM P+DE+L  + + R   ++ ++ +EL  +P S  IGS+  +  KI+ +  + +     ++ E  + ++        +  +  +  +++ +   K + +    S+V       IK+                 +K L  L EL Q+  FN  K  +LP  V    ++  V        ++  ++      +C  ++++  L          D FW+IF  +Y    +K+  +N F R ++ Y   LF++   K + +E   K LP+LLS+A+Y +   CFP SW    ++F  +I   +  W+SG  P+  S+  W+  EL P
Sbjct:    4 FRKMEVINLTTLPMIPVDEHLAVSLVARNTMVKTVR-KELENNPPSCLIGSMHQVNQKIADINLRTEPSANSLAIERFELEKKALREKTRSSPEDKVKRQRKSQYSCKGSELRHARSSV-------IKRKTA--------------DKNL--LAELYQYSNFNSSKPNKLPNGVDFCDMVGNV--------VRAERDCLSGKHFCSGRELEKFLSSSSPRAIWLDSFWWIFHERY--QPNKELQNNLFDRIAQHYALLLFRVP--KSHSEEALLKRLPSLLSKAVYTSFCCCFPQSWFD-THEFKSDICNTMSLWISGTYPSPQSYDSWDYSELDP 302
[Close]
BLAST of Family with sequence similarity 227 member B vs. TrEMBL
Match: A0A267E6Z4 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006086g5 PE=4 SV=1)

HSP 1 Score: 177.563 bits (449), Expect = 1.115e-45
Identity = 115/342 (33.63%), Postives = 189/342 (55.26%), Query Frame = 2 
Query:   44 NTLNRFCSPMHPMDENLD-DTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEV-VDNGGNDNQIQVNLNIK-----KEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKA---LPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQ 1039
            N LNR  SPM   D  +  D D  ++   E+ K  + T+SP+ IGSV  I  +I KL+ ++K F    + +D+  + + VD    D  ++ N+++K     ++  E  KFAG++S  +       ER+KKI K S++  + +       A    P+ +ELCQ PG+N  ++T LP  VQP  IL RV  +QP  F   YK   D+ F  +  + +L+D FW+ F+  YG D DK ++  +++R + +Y   LF I +E  ++++ F K  P+LLSQA+Y A    FP S+ +F  +F E I+ LV  WL+G++P    W  WN + L+P+  + +E+ ++ +
Sbjct:    1 NYLNRNGSPMLHFDTEVPLDQDTHKKIVAEYEKQSQ-TRSPFQIGSVELISQRIGKLDRKLKEF----TPDDVSKESLFVD----DIDVRANMSVKDIVTDQQMLEKTKFAGVYSFGTNFGLPNSERVKKIEKISMQKKTSNFYSSPKGAQNDRPQFVELCQFPGYNQRELTPLPCGVQPVDILIRVMAAQPGRFSSQYKAQLDRCFLSEASKAVLQDAFWHHFLDHYGQDYDKPEMPRFYNRIAHNYSQMLFMIKVE--HFRDAFLKSYPSLLSQAVYSAYCNAFPHSFSKFQAEFKEGIVCLVHRWLTGLQPRCRLWLDWNKDALEPSVIRHREELLKAE 331
[Close]
BLAST of Family with sequence similarity 227 member B vs. TrEMBL
Match: A0A1I8J8H9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 165.236 bits (417), Expect = 2.775e-43
Identity = 109/338 (32.25%), Postives = 180/338 (53.25%), Query Frame = 2 
Query:   41 MNTLNRFCSPMHPMDENLD-DTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETK-ISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKA---LPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQ 1039
            MN LNR  SPM   D  +  D D  ++   E+ K  + T+SP+ IGSV  I  +I KL+ ++K F    +S E +  D++         ++ N+++K              +++       ER+KKI K S++  + +       A    P+ +ELCQ PG+N  ++T LP  VQP  IL RV  +QP  F   YK   D+ F  +  + +L+D FW+ F+  YG D DK ++  +++R + +Y   LF I +E  ++++ F K  P+LLSQA+Y A    FP S+ +F  +F E I+ LV  WL+G++P    W  WN + L+P+  + +E+ ++ +
Sbjct:    1 MNYLNRNGSPMLHFDTEVPLDQDTHKKIVAEYEKQSQ-TRSPFQIGSVELISQRIGKLDRKLKEFTPDDVSKESLFVDDI--------DVRANMSVK-------------DIVTDFGLPNSERVKKIEKISMQKKTSNFYSSPKGAQNDRPQFVELCQFPGYNQRELTPLPCGVQPVDILIRVMAAQPGRFSSQYKAQLDRCFLSEASKAVLQDAFWHHFLDHYGQDYDKPEMPRFYNRIAHNYSQMLFMIKVE--HFRDAFLKSYPSLLSQAVYSAYCNAFPHSFSKFQAEFKEGIVCLVHRWLTGLQPRCRLWLDWNKDALEPSVIRHREELLKAE 314
[Close]
BLAST of Family with sequence similarity 227 member B vs. TrEMBL
Match: A0A1S3JEK6 (protein FAM227B OS=Lingula unguis OX=7574 GN=LOC106172421 PE=4 SV=1)

HSP 1 Score: 171.4 bits (433), Expect = 5.816e-43
Identity = 115/343 (33.53%), Postives = 184/343 (53.64%), Query Frame = 2 
Query:   41 MNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDN------------GGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKALPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQ-PLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAI 1030
            M  +NR  SPMH  +E++++T  + EK+   I+ R+ TKSP+ IGS+  +  KISKL+ ++  +   +   +  S E  D+            G    + +V     K+ KE+  FAG +++ ST+     ER++ I K +L+         +    PK IEL Q PG++  ++T+LP  +    IL +V  +Q  L     Y+  F+K FY    Q +L D+FW+ F+ KY    +K   +  F+R S +YV  +  I  + P Y+E F K  P+L+SQA+Y A  E FPDS+ QF+ DF E ++ LV+ W++G+RP   SW  WN   L+P   K +E+ +
Sbjct:    1 MADINRTASPMHLFEEDINETRDVTEKRRRLIQDRQHTKSPFLIGSIDLVNKKISKLDRKLSHYSELVC--ESQSTETEDDYIAQFLHPSSAKGREKYEKKV-----KDAKELNAFAGFYALQSTIGHEVSERVRNISKVTLQPNKIPVKKVET-GKPKFIELHQFPGYDPTELTQLPHDISATQILNKVTFAQMDLKRKPNYRPEFEKLFYSPMSQAMLLDIFWFYFLEKY--QPNKVVQAKLFNRVSHNYVKLM--IYAKHPQYKEVFLKSYPDLMSQAVYAAYCEAFPDSYRQFSEDFKEMMVFLVWEWMAGMRPAPRSWLKWNFPMLEPPGIKNREEMM 331
[Close]
BLAST of Family with sequence similarity 227 member B vs. TrEMBL
Match: A0A1I8GZ37 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 164.851 bits (416), Expect = 9.887e-43
Identity = 107/337 (31.75%), Postives = 181/337 (53.71%), Query Frame = 2 
Query:   41 MNTLNRFCSPMHPMDENLD-DTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKA---LPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQ 1039
            MN LNR  SPM   D  +  D D  ++   E+ K  + T+SP+ IGSV  I  +I KL+ ++K F    + +D+  + +     +D  ++ N++++              +++       ER+KKI K S++  + +       A    P+ +ELCQ PG+N  ++T LP  VQP  IL RV  +QP  F   YK   D+ F  +  + +L+D FW+ F+  YG D DK ++  +++R + +Y   LF I +E  ++++ F K  P+LLSQA+Y A    FP S+ +F  +F E I+ LV  WL+G++P    W  WN + L+P+  + +E+ ++ +
Sbjct:    1 MNYLNRNGSPMLHFDTEVPLDQDTHKKIVAEYEKQSQ-TRSPFQIGSVELISQRIGKLDRKLKEF----TPDDVSKESLF---VDDIDVRANMSVE-------------DIVTDFGLPNSERVKKIEKISMQKKTSNFYSSPKGAQNDRPQFVELCQFPGYNQRELTPLPCGVQPVDILIRVMAAQPGRFSSQYKAQLDRCFLSEASKAVLQDAFWHHFLDHYGQDYDKPEMPRFYNRIAHNYSQMLFMIKVE--HFRDAFLKSYPSLLSQAVYSAYCNAFPHSYSKFQAEFKEGIVCLVHRWLTGLQPRCRLWLDWNKDALEPSVIRHREELLKAE 314
[Close]
BLAST of Family with sequence similarity 227 member B vs. TrEMBL
Match: A0A267F119 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig001047g3 PE=4 SV=1)

HSP 1 Score: 167.933 bits (424), Expect = 3.730e-42
Identity = 112/343 (32.65%), Postives = 182/343 (53.06%), Query Frame = 2 
Query:   41 MNTLNRFCSPMHPMDENLD-DTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEV-VDNGGNDNQIQVNLNIK-----KEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKA---LPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQ 1039
            MN LNR  SPM   D  +  D D  ++   E+ K  + T+SP+ IGSV  I  +I KL+ ++K F    + +D+  + + VD    D  ++ N++++     ++  E  KFAG++S  +       ER+KKI K S++  + +       A    P+ +ELCQ PG+N  ++T LP  VQP  IL RV  +QP  F   YK   D+ F  +  + +L+D FW+ F+  YG D DK ++  +++R + +Y   LF I            K  P+LLSQA+Y      FP S+ +F  +F E I+ LV  WL+G++P    W  WN + L+P+  + +E+ ++ +
Sbjct:    3 MNYLNRNGSPMLHFDTEVPLDQDTHKKIVAEYEKQSQ-TRSPFQIGSVELISQRIGKLDRKLKEF----TPDDVSKESLFVD----DIDVRANMSVEDIVTDQQMLEKTKFAGVYSFGTNFGLPNSERVKKIEKISMQKKTSNFYSSPKGAQNDRPQFVELCQFPGYNQRELTPLPCGVQPVDILIRVMAAQPGRFSSQYKAQLDRCFLSEASKAVLQDAFWHHFLDHYGQDYDKPEMPRFYNRIAHNYSQMLFMI------------KSYPSLLSQAVYSVYCNAFPHSYSKFQAEFKEGIVCLVHRWLTGLQPRCRLWLDWNKDALEPSVIRHREELLKAE 324
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Nematostella
Match: EDO47949 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKR0])

HSP 1 Score: 102.064 bits (253), Expect = 2.305e-23
Identity = 47/139 (33.81%), Postives = 81/139 (58.27%), Query Frame = 2 
Query:  608 YKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEK 1024
            YK++          Q +L+D+FW+ F+ +Y SD   ++L   F+R + +YV  LF   + +  Y++ F K  P+L++QA+Y      FP S+ QF+  F E ++QLV+ W+ G++P   SW  W ++ L+PT+ +  EK
Sbjct:   41 YKKYLHSLLLSHMSQAVLQDVFWWYFLERYQSDRSTQEL--LFNRIAHNYVKLLFNAPITE--YRDAFFKRYPDLVNQAVYCTFCTAFPTSYKQFDGKFKEGLVQLVYMWMVGVKPVPRSWERWKLDALEPTDMRKDEK 175
[Close]
BLAST of Family with sequence similarity 227 member B vs. Ensembl Nematostella
Match: EDO46128 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR91])

HSP 1 Score: 70.0922 bits (170), Expect = 5.107e-15
Identity = 32/89 (35.96%), Postives = 54/89 (60.67%), Query Frame = 2 
Query:  734 FSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKP 1000
            FSR ++S+V   F +  +   Y++ F K  P+ L+QALY +  + FP S+  F++DF  ++M  V+ W++G RP   SW  W+ + L+P
Sbjct:    2 FSRIADSFVALFFSVPGD---YKDNFFKYYPDCLAQALYASYCDVFPRSYNLFDDDFKTDLMNGVYEWITGTRPPPRSWQKWHFKMLEP 87
[Close]
BLAST of Family with sequence similarity 227 member B vs. Planmine SMEST
Match: SMESG000052176.1 (SMESG000052176.1)

HSP 1 Score: 746.888 bits (1927), Expect = 0.000e+0
Identity = 388/406 (95.57%), Postives = 396/406 (97.54%), Query Frame = 2 
Query:   41 MNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKALPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWFLERNSLETKRFQKLQKISN 1258
            MNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVKKSLKNPSKSKLHFDNKALPKLIELCQHPGFNW KITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENI+QLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQW+ ++N++      K+  +SN
Sbjct:    1 MNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVKKSLKNPSKSKLHFDNKALPKLIELCQHPGFNWQKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIIQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWYFKKNNININVGTKIILLSN 406
[Close]
BLAST of Family with sequence similarity 227 member B vs. Planmine SMEST
Match: SMESG000052176.1 (SMESG000052176.1)

HSP 1 Score: 741.495 bits (1913), Expect = 0.000e+0
Identity = 385/393 (97.96%), Postives = 391/393 (99.49%), Query Frame = 2 
Query:   41 MNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKALPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWFLERNSL 1219
            MNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVKKSLKNPSKSKLHFDNKALPKLIELCQHPGFNW KITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENI+QLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQW+ ++N++
Sbjct:    1 MNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVKKSLKNPSKSKLHFDNKALPKLIELCQHPGFNWQKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIIQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWYFKKNNI 393
[Close]
BLAST of Family with sequence similarity 227 member B vs. Planmine SMEST
Match: SMESG000052176.1 (SMESG000052176.1)

HSP 1 Score: 741.495 bits (1913), Expect = 0.000e+0
Identity = 385/393 (97.96%), Postives = 391/393 (99.49%), Query Frame = 2 
Query:   41 MNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKALPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWFLERNSL 1219
            MNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVKKSLKNPSKSKLHFDNKALPKLIELCQHPGFNW KITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENI+QLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQW+ ++N++
Sbjct:    1 MNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVKKSLKNPSKSKLHFDNKALPKLIELCQHPGFNWQKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIIQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWYFKKNNI 393
[Close]
BLAST of Family with sequence similarity 227 member B vs. Planmine SMEST
Match: SMESG000046302.1 (SMESG000046302.1)

HSP 1 Score: 736.102 bits (1899), Expect = 0.000e+0
Identity = 382/393 (97.20%), Postives = 389/393 (98.98%), Query Frame = 2 
Query:   41 MNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKALPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWFLERNSL 1219
            MNTLNRFCSPMHPMDENLDDTDIIREKKI+FIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVKKSLKNPSKSKLHFDNKALPKLIELCQHPGFNW KITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLL DMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENI+QLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKE AIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQW+ ++N++
Sbjct:    1 MNTLNRFCSPMHPMDENLDDTDIIREKKIKFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVKKSLKNPSKSKLHFDNKALPKLIELCQHPGFNWQKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLNDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIIQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKENAIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWYFKKNNI 393
[Close]
BLAST of Family with sequence similarity 227 member B vs. Planmine SMEST
Match: SMESG000046302.1 (SMESG000046302.1)

HSP 1 Score: 712.99 bits (1839), Expect = 0.000e+0
Identity = 372/383 (97.13%), Postives = 379/383 (98.96%), Query Frame = 2 
Query:   71 MHPMDENLDDTDIIREKKIEFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVXXXXXXXXXXXXHFDNKALPKLIELCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWFLERNSL 1219
            MHPMDENLDDTDIIREKKI+FIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVKKSLKNPSKSKLHFDNKALPKLIELCQHPGFNW KITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLL DMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENI+QLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKE AIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQW+ ++N++
Sbjct:    1 MHPMDENLDDTDIIREKKIKFIKLRELTKSPYSIGSVIDIENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKEVEKFAGIFSVISTVDFNKPERIKKIVKKSLKNPSKSKLHFDNKALPKLIELCQHPGFNWQKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYCQKIQDLLNDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEKPYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIIQLVFFWLSGIRPTKGSWSCWNMEELKPTEQKLKENAIEEQLRIGFSDLQIEKKTPEKDQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWYFKKNNI 383
The following BLAST results are available for this feature:
BLAST of Family with sequence similarity 227 member B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FAM227B1.114e-2532.49family with sequence similarity 227 member B [Sour... [more]
FAM227A5.352e-1523.51family with sequence similarity 227 member A [Sour... [more]
FAM227A5.985e-1523.51family with sequence similarity 227 member A [Sour... [more]
FAM227A6.878e-1523.96family with sequence similarity 227 member A [Sour... [more]
FAM227B1.337e-1227.67family with sequence similarity 227 member B [Sour... [more]
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BLAST of Family with sequence similarity 227 member B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Family with sequence similarity 227 member B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Family with sequence similarity 227 member B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Family with sequence similarity 227 member B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSXETT00000000957.11.223e-2626.63family with sequence similarity 227 member A [Sour... [more]
ENSXETT00000055522.12.660e-2027.82family with sequence similarity 227 member B [Sour... [more]
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BLAST of Family with sequence similarity 227 member B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Fam227b1.219e-2433.65family with sequence similarity 227, member B [Sou... [more]
Fam227b1.375e-2433.65family with sequence similarity 227, member B [Sou... [more]
Fam227b1.375e-2433.65family with sequence similarity 227, member B [Sou... [more]
Fam227a1.960e-1231.25family with sequence similarity 227, member A [Sou... [more]
Fam227a1.969e-1231.25family with sequence similarity 227, member A [Sou... [more]
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BLAST of Family with sequence similarity 227 member B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q96M60|F227B_HUMAN5.352e-2532.49Protein FAM227B OS=Homo sapiens OX=9606 GN=FAM227B... [more]
sp|Q9D518|F227B_MOUSE9.620e-2433.65Protein FAM227B OS=Mus musculus OX=10090 GN=Fam227... [more]
sp|Q4R7D5|F227B_MACFA9.532e-2233.01Protein FAM227B OS=Macaca fascicularis OX=9541 GN=... [more]
sp|Q6AXP3|F227B_RAT4.979e-2031.22Protein FAM227B OS=Rattus norvegicus OX=10116 GN=F... [more]
sp|F5H4B4|F227A_HUMAN2.570e-1423.51Protein FAM227A OS=Homo sapiens OX=9606 GN=FAM227A... [more]
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BLAST of Family with sequence similarity 227 member B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267E6Z41.115e-4533.63Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1I8J8H92.775e-4332.25Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1S3JEK65.816e-4333.53protein FAM227B OS=Lingula unguis OX=7574 GN=LOC10... [more]
A0A1I8GZ379.887e-4331.75Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267F1193.730e-4232.65Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
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BLAST of Family with sequence similarity 227 member B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Family with sequence similarity 227 member B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Family with sequence similarity 227 member B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Family with sequence similarity 227 member B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO479492.305e-2333.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO461285.107e-1535.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Family with sequence similarity 227 member B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Family with sequence similarity 227 member B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000052176.10.000e+095.57SMESG000052176.1[more]
SMESG000052176.10.000e+097.96SMESG000052176.1[more]
SMESG000052176.10.000e+097.96SMESG000052176.1[more]
SMESG000046302.10.000e+097.20SMESG000046302.1[more]
SMESG000046302.10.000e+097.13SMESG000046302.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002718 ID=SMED30002718|Name=Family with sequence similarity 227 member B|organism=Schmidtea mediterranea sexual|type=transcript|length=1430bp
TATATAAATCTTATATGAAAATTGAAAAAAATATTTCAAAATGAATACAT
TGAATCGGTTTTGTTCTCCAATGCATCCAATGGATGAAAATTTGGATGAT
ACTGATATTATTCGTGAAAAGAAAATTGAATTTATTAAACTAAGAGAACT
TACGAAATCTCCTTATTCAATTGGATCTGTAATTGACATTGAAAATAAAA
TTTCTAAATTAGAGGAACAGATTAAAGGTTTTGAAACGAAAATTTCATGG
GAAGACATTGACTCAGACGAAGTGGTTGATAATGGTGGTAATGATAATCA
AATACAAGTTAATTTAAACATTAAAAAAGAAAAAAAAGAGGTAGAAAAAT
TTGCTGGAATATTTTCTGTAATCTCTACTGTGGACTTTAATAAACCAGAA
AGAATAAAGAAAATTGTTAAAAAATCTTTGAAAAACCCGTCAAAATCAAA
ATTGCATTTTGATAATAAAGCTCTTCCAAAACTAATTGAGCTATGTCAAC
ACCCAGGATTCAACTGGATAAAAATTACAGAATTACCATTTTCTGTACAA
CCTGAATTTATTTTAAAGCGAGTGCATGAGTCCCAACCATTGACGTTCAT
TAAAATCTACAAAGAATTTTTCGACAAATGGTTCTACTGCCAAAAAATAC
AAGATCTTCTGAAAGATATGTTTTGGTACATCTTCATTTCTAAATATGGT
TCGGATGTCGATAAAAAAGATTTGAGTAATTATTTTTCTCGAGCTTCCGA
AAGTTATGTTGGATTTCTTTTCAAAATAACAATGGAAAAGCCATATTATC
AAGAAAAATTTAAAAAAGTGCTTCCGAACTTACTTAGCCAAGCTCTTTAC
GTAGCATTATCTGAATGCTTTCCAGATTCCTGGATCCAATTCAATAATGA
TTTTGTAGAGAATATTATGCAATTAGTGTTCTTTTGGCTAAGTGGAATAA
GACCTACTAAAGGATCTTGGAGTTGTTGGAATATGGAAGAACTTAAGCCT
ACTGAACAGAAATTAAAAGAAAAGGCAATTGAAGAACAATTACGCATTGG
ATTTTCGGATCTTCAGATTGAAAAGAAAACACCTGAGAAGGATCAGTTGA
AAAATTCAGTTTCGACAAAATCAACTTTACTTGGAGCTTTGAACCATTCA
AACAATGTCCTATTTAATGTCAGTGGACACAGCCCTTTAATTCAGTGGTT
TCTTGAACGAAATTCTTTAGAAACAAAACGATTTCAGAAACTTCAAAAAA
TAAGCAATTTTAGCAATGAAAAAAGACAAGAAAAACTGTTACTGAATAAA
TCAAAAATTCATAAATTAAGTAATTTAATTATGCATGAATATTTGAAAGA
TAAAGATTCAATTTCTTTTGGGGCCGACAAAGCAGTTACAGATGCAATTC
AGGAAGCCTAATAAATGATGTAACTCTTTG
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protein sequence of SMED30002718-orf-1

>SMED30002718-orf-1 ID=SMED30002718-orf-1|Name=SMED30002718-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=457bp
MNTLNRFCSPMHPMDENLDDTDIIREKKIEFIKLRELTKSPYSIGSVIDI
ENKISKLEEQIKGFETKISWEDIDSDEVVDNGGNDNQIQVNLNIKKEKKE
VEKFAGIFSVISTVDFNKPERIKKIVKKSLKNPSKSKLHFDNKALPKLIE
LCQHPGFNWIKITELPFSVQPEFILKRVHESQPLTFIKIYKEFFDKWFYC
QKIQDLLKDMFWYIFISKYGSDVDKKDLSNYFSRASESYVGFLFKITMEK
PYYQEKFKKVLPNLLSQALYVALSECFPDSWIQFNNDFVENIMQLVFFWL
SGIRPTKGSWSCWNMEELKPTEQKLKEKAIEEQLRIGFSDLQIEKKTPEK
DQLKNSVSTKSTLLGALNHSNNVLFNVSGHSPLIQWFLERNSLETKRFQK
LQKISNFSNEKRQEKLLLNKSKIHKLSNLIMHEYLKDKDSISFGADKAVT
DAIQEA*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002032epidermal cell
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR029417FAM227
Vocabulary: molecular function
TermDefinition
GO:0003674molecular_function
Vocabulary: cellular component
TermDefinition
GO:0005575cellular_component
Vocabulary: biological process
TermDefinition
GO:0008150biological_process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 47..67
IPR029417FAM227 ProteinPFAMPF14922FWWhcoord: 163..314
e-value: 1.1E-35
score: 122.8
IPR029417FAM227 ProteinPANTHERPTHR33560FAMILY NOT NAMEDcoord: 345..400
coord: 1..349