transmembrane emp24 domain-containing protein eca-like

Overview
Nametransmembrane emp24 domain-containing protein eca-like
Smed IDSMED30002714
Length (bp)894
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of transmembrane emp24 domain-containing protein eca-like (SMED30002714) t-SNE clustered cells

Violin plots show distribution of expression levels for transmembrane emp24 domain-containing protein eca-like (SMED30002714) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of transmembrane emp24 domain-containing protein eca-like (SMED30002714) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for transmembrane emp24 domain-containing protein eca-like (SMED30002714) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30002714

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30002714h1SMcG0012562 Contig44407newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30002714h1SMcG0012562 Contig44407uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30002714h1SMcG0012562 dd_Smed_v4_1023_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30002714h1SMcG0012562 dd_Smed_v4_1023_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30002714h1SMcG0012562 dd_Smed_v4_1023_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30002714h1SMcG0012562 dd_Smed_v4_1023_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Human
Match: TMED4 (transmembrane p24 trafficking protein 4 [Source:HGNC Symbol;Acc:HGNC:22301])

HSP 1 Score: 270.011 bits (689), Expect = 1.743e-90
Identity = 128/202 (63.37%), Postives = 161/202 (79.70%), Query Frame = 3 
Query:  117 NTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
                +YFHI ETE +CFIEE+P++TM++G Y+T+++DK K V++P+  GLGMHVE+ DP+ KVVLSR Y SEGRF  T+H+ G+  ICLHSNS+    F G KLRVHL+IQ GEHA +Y EIAAKDKLT+LQLR RQL+DQVEQI KEQ+YQR RE RFR TSESTN RVL++S+ Q  +L++ G WQM++LKSFF AKKLV
Sbjct:   26 GAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV 227
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Human
Match: TMED9 (transmembrane p24 trafficking protein 9 [Source:HGNC Symbol;Acc:HGNC:24878])

HSP 1 Score: 267.7 bits (683), Expect = 1.976e-89
Identity = 133/211 (63.03%), Postives = 165/211 (78.20%), Query Frame = 3 
Query:   96 FLSVFILNT--NAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVW--FGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
             L V  L T  +A+YFHI ETE KCFIEE+P++TM++G Y+T+++DK +  Y P   GLGM VE+ DPE KV+L+R Y SEGRF  T+H+ GE  ICLHSNS+ +  F G  LRVHL+IQ GEHA DY EIAAKDKL++LQLRVRQL++QVEQI KEQNYQR RE RFR TSESTN RVL++S++Q  +LV +G WQM++LKSFF AKKLV
Sbjct:   25 LLLVLWLATRGSALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPATPGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKLV 235
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Human
Match: TMED4 (transmembrane p24 trafficking protein 4 [Source:HGNC Symbol;Acc:HGNC:22301])

HSP 1 Score: 219.935 bits (559), Expect = 2.174e-71
Identity = 97/153 (63.40%), Postives = 122/153 (79.74%), Query Frame = 3 
Query:  117 NTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQR 569
                +YFHI ETE +CFIEE+P++TM++G Y+T+++DK K V++P+  GLGMHVE+ DP+ KVVLSR Y SEGRF  T+H+ G+  ICLHSNS+    F G KLRVHL+IQ GEHA +Y EIAAKDKLT+LQLR RQL+DQVEQI KEQ+YQR
Sbjct:   26 GAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQR 178
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Human
Match: TMED4 (transmembrane p24 trafficking protein 4 [Source:HGNC Symbol;Acc:HGNC:22301])

HSP 1 Score: 166.392 bits (420), Expect = 1.576e-50
Identity = 89/202 (44.06%), Postives = 117/202 (57.92%), Query Frame = 3 
Query:  117 NTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
                +YFHI ETE +CFIEE+P++TM++G Y+T+++DK K V++P+  GLGMHVE+ DP+ KVVLSR Y SEGRF  T+H+ G+  ICLHSNS+    F G KL                                                  RE RFR TSESTN RVL++S+ Q  +L++ G WQM++LKSFF AKKLV
Sbjct:   26 GAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLY-------------------------------------------------REERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV 178
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Human
Match: TMED10 (transmembrane p24 trafficking protein 10 [Source:HGNC Symbol;Acc:HGNC:16998])

HSP 1 Score: 114.775 bits (286), Expect = 3.856e-30
Identity = 71/197 (36.04%), Postives = 111/197 (56.35%), Query Frame = 3 
Query:  126 AIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            AI FH+     KC  EE+ +D ++ G Y  EI D+S         GL  H++ITD    ++ S+  +++G+F  TT     F +C  S  +         V L+++ G  A++Y+EIA  +KL  L++ +R+L D  E I  +  Y + RE   RDT+ESTN+RVLYFS+  +  L+ +  WQ+  L+ FF+AKKL+
Sbjct:   31 AISFHLPINSRKCLREEIHKDLLVTGAY--EISDQSGGA-----GGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRI--PDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLI 218
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Celegans
Match: Y60A3A.9 (pep chromosome:WBcel235:V:19946691:19949093:-1 gene:WBGene00013360.1 transcript:Y60A3A.9.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y60A3A.9)

HSP 1 Score: 256.914 bits (655), Expect = 6.047e-86
Identity = 122/212 (57.55%), Postives = 165/212 (77.83%), Query Frame = 3 
Query:   87 ISIFLSVFILNT--NAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            + + +++  L T  +++YFHI ETE KCFIEE+P++TM+ G YK +++D +   Y      +GMHVE+ DPE KV+LS+ Y++EGRF  T+++ GE  IC++SNS+ WF GA+LRVHL+IQ G+HAQDY +IA KDKL +LQLR+RQL+DQV+QITKEQNYQR RE RFR TSESTNSRV Y+S+ QV +L + G WQM++L+ FF AKKLV
Sbjct:    1 MRLLIALLSLATYADSLYFHIAETEKKCFIEEIPDETMVTGNYKVQLYDPNTKGY-GDYPNIGMHVEVKDPEDKVILSKLYTAEGRFTFTSNTPGEHVICIYSNSTAWFNGAQLRVHLDIQAGDHAQDYAQIAQKDKLNELQLRIRQLLDQVDQITKEQNYQRYREERFRQTSESTNSRVFYWSIAQVVVLAITGAWQMRHLRGFFEAKKLV 211
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Celegans
Match: T08D2.1 (pep chromosome:WBcel235:X:162529:163134:-1 gene:WBGene00011606.1 transcript:T08D2.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T08D2.1)

HSP 1 Score: 155.221 bits (391), Expect = 7.408e-47
Identity = 67/138 (48.55%), Postives = 101/138 (73.19%), Query Frame = 3 
Query:   87 ISIFLSVFILNT--NAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKL 494
            + + +++  L T  +++YFHI ETE KCFIEE+P++TM+ G YK +++D +   Y      +GMHVE+ DPE KV+LS+ Y+SEGRF  T+++ GE  IC++SN++ WF GA+LRVHL+IQ G+HAQDY ++  + KL
Sbjct:    1 MRLLIALLSLATYADSLYFHIAETEKKCFIEEIPDETMVTGNYKVQLYDPNTKGY-GDYPNIGMHVEVKDPEDKVILSKLYTSEGRFTFTSNTPGEHVICIYSNTTAWFNGAQLRVHLDIQAGDHAQDYAQVEEERKL 137
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Celegans
Match: F47G9.1 (pep chromosome:WBcel235:V:11323965:11326964:-1 gene:WBGene00009829.1 transcript:F47G9.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F47G9.1)

HSP 1 Score: 102.834 bits (255), Expect = 3.240e-26
Identity = 64/212 (30.19%), Postives = 115/212 (54.25%), Query Frame = 3 
Query:   87 ISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSE--GRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            + IFLS  +L  +++ F++   E KC  EE+ ++ ++ G+Y+          +   +   G  + +TD     +  R   ++  G+F  T      F IC+ ++      G K  V L ++ G  A++Y +IA  +KL  L++ +R+L D  + ITK+  + R RE   R+T+ESTNSRVLY S+  +  L+ +  WQ+  L+++F++KKL+
Sbjct:    4 LVIFLSAIVL-AHSLRFYVPPKEKKCLKEEIHKNVVVTGEYE----------FSQGIQYTG-SIHVTDTRGHTLYKRENFADLKGKFAFTADEYDIFEICIENHPPAGHPGEKREVSLILKHGVEAKNYDDIAKAEKLKPLEVELRRLEDMADSITKDFAFMRQREEEMRNTNESTNSRVLYLSIFSMLCLLGLAIWQVLFLRNYFKSKKLI 203
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Celegans
Match: sel-9 (Suppressor/enhancer of lin-12 protein 9 [Source:UniProtKB/Swiss-Prot;Acc:O17528])

HSP 1 Score: 58.151 bits (139), Expect = 7.142e-10
Identity = 51/211 (24.17%), Postives = 89/211 (42.18%), Query Frame = 3 
Query:   87 ISIFLSVFILNTNAIYF-HIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            ++  L+V  +   A YF H+   E +CF      D +  G     +F+ ++  +      L + V+IT P+ K +      S G+F    H  G +  C  +  S     A +      +  + A              L+  VR+L   +  +  EQ Y   RE   R+ +E+TNSRV+ ++  +  +LV +   Q+  LK FF  + +V
Sbjct:    4 LTWILAVLFVTPAASYFIHVDANEEQCFF-----DRLTSGTKMGLMFEVAEGGF------LDIDVKITGPDNKEIYKGERESSGKFTFAAHMDGVYTYCFGNKMSTMTPKAVMFTVEITEPHQQAPGAAANQDAADNAKLEEMVRELSSALMSVKHEQEYMEVRERVHRNINENTNSRVVMWAAFEAFVLVGMTVGQIFYLKRFFEVRTMV 203
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Fly
Match: eca (gene:FBgn0069242 transcript:FBtr0082098)

HSP 1 Score: 268.085 bits (684), Expect = 2.775e-90
Identity = 131/212 (61.79%), Postives = 168/212 (79.25%), Query Frame = 3 
Query:   84 FISIFLSVFILNTN-AIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            FIS+ L + +L++   +YFHI ETE KCFIEEVP++T ++  YK E++D   N ++P+  G+GMHVE+ D + K+VLSR YSS+GR   T+H+ GE  IC+ SNS+ WF GA+LRVHL+IQ GEHA DY  +A K+KLT+LQLR+RQL+DQVEQITKEQNYQR RE RFR TSESTNSRVL++SL Q  +LV +GFWQM++LKSFF AKKLV
Sbjct:    5 FISLALILCVLHSACGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMRHLKSFFEAKKLV 216
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Fly
Match: p24-2 (gene:FBgn0053105 transcript:FBtr0082093)

HSP 1 Score: 246.899 bits (629), Expect = 1.875e-81
Identity = 120/202 (59.41%), Postives = 157/202 (77.72%), Query Frame = 3 
Query:   84 FISIFLSVFILNTNA-IYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNL 686
            FIS+ L + +L++   +YFHI +TE KCFIEEVP++T ++  YK E++D   N ++P+  G+GMHVE+ D + K+VLSR YSS+GR   T+H+ GE  IC+ SNS+ WF GA+LRVHL+IQ GEHA DY  +A K+KLT+LQLR+RQL+DQVEQITKEQNYQR RE RFR TSESTNSRVL++SL Q  +LV +GFW + NL
Sbjct:    5 FISLALILCVLHSACGLYFHISQTERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWHLFNL 206
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Fly
Match: p24-2 (gene:FBgn0053105 transcript:FBtr0303038)

HSP 1 Score: 246.899 bits (629), Expect = 1.875e-81
Identity = 120/202 (59.41%), Postives = 157/202 (77.72%), Query Frame = 3 
Query:   84 FISIFLSVFILNTNA-IYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNL 686
            FIS+ L + +L++   +YFHI +TE KCFIEEVP++T ++  YK E++D   N ++P+  G+GMHVE+ D + K+VLSR YSS+GR   T+H+ GE  IC+ SNS+ WF GA+LRVHL+IQ GEHA DY  +A K+KLT+LQLR+RQL+DQVEQITKEQNYQR RE RFR TSESTNSRVL++SL Q  +LV +GFW + NL
Sbjct:    5 FISLALILCVLHSACGLYFHISQTERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWHLFNL 206
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Fly
Match: bai (gene:FBgn0045866 transcript:FBtr0084758)

HSP 1 Score: 80.8777 bits (198), Expect = 7.410e-18
Identity = 54/212 (25.47%), Postives = 101/212 (47.64%), Query Frame = 3 
Query:   81 TFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
             FI   L     +++A+ F +     KC  E++  + +++G+++           V  V G  +     D +  ++  + + ++G+F   +     + IC  S       G    V L  + G   + Y+ I    KL  L++ +++L D  + I ++    R RE   RDT+E TNSRVL+FS+  +  L+ +  WQ+  L+ +F+AKKL+
Sbjct:    5 AFIVCLLMACAWSSHAVMFKLSPNTQKCLKEDIQANQLVMGEFE-----------VSDVPGQIIDYIARDTKGHILSQKEHITKGKFSFMSEVYDTYEICFISKVPAHQRGVIQEVSLLTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSDSIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Fly
Match: CHOp24 (gene:FBgn0029709 transcript:FBtr0343566)

HSP 1 Score: 52.7582 bits (125), Expect = 6.934e-8
Identity = 40/153 (26.14%), Postives = 75/153 (49.02%), Query Frame = 3 
Query:  264 LGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKL--TDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            L + ++I+ P+  V+      S G++     + G + +C ++  S      KL V   I  G+  Q       ++++  T L+  +R+L   +  +  EQ Y   R+   R  +E+TNSRV+ +S  +  +LV++   Q+  LK FF  K++V
Sbjct:   59 LDVDIKISGPDNHVMHESEKESSGKYTFVAPAKGTYTVCFNNERSSM--TPKL-VMFSIDVGDAPQRAPGAPGEEEVGHTKLEDMIRELSGTLTSVKHEQEYMHVRDKIHRSVNENTNSRVVLWSTFEALVLVLMTVGQVYYLKRFFEVKRVV 208
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Zebrafish
Match: tmed4 (transmembrane p24 trafficking protein 4 [Source:ZFIN;Acc:ZDB-GENE-040625-140])

HSP 1 Score: 279.641 bits (714), Expect = 1.770e-94
Identity = 135/224 (60.27%), Postives = 173/224 (77.23%), Query Frame = 3 
Query:   51 FKIMNNCMTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
             K + +C+ F  + ++LS     + A+YFHI ETE KCFIEE+P++TM++G+Y+T+++DK    ++P+  GLGMHVEI DPE KV+LSR Y S+GRF  T+H+ GE  ICLHSNS+    F G KLRVHL+IQ GEH  +Y EIAAKDKLT+LQLRVRQL+DQVEQI KEQNYQR RE RFR TSESTN RVL++S+ Q  +L++ G WQM++LKSFF AKKLV
Sbjct:    6 MKTLVSCVGFLLLFVWLS----PSQALYFHIGETEKKCFIEEIPDETMVIGRYRTQLWDKQAGSFLPSTPGLGMHVEIKDPETKVILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGKLRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSIAQTVILIITGIWQMKHLKSFFEAKKLV 225
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Zebrafish
Match: tmed9 (transmembrane p24 trafficking protein 9 [Source:ZFIN;Acc:ZDB-GENE-050417-434])

HSP 1 Score: 275.404 bits (703), Expect = 7.544e-93
Identity = 136/218 (62.39%), Postives = 172/218 (78.90%), Query Frame = 3 
Query:   72 MTFT-FISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            M FT +  + L+++    +A+YFHI ETE KCFIEE+P++TMI+G Y+T+++DK K  Y+P   GLGM VE+ DP++KV+LSR Y SEGRF+ T+H+ GE  ICLHSNSS    F G  LRVHL+IQ GEH  +Y EIAAKDKLT+LQLRVRQL++QV+QI KEQNYQR RE RFR TSESTN RVL++S+VQ  +LV +GFWQM++LKSFF AKKLV
Sbjct:    6 MQFTLYFLVLLNIYNSLVSALYFHIGETEKKCFIEEIPDETMIIGNYRTQLYDKQKEEYLPATQGLGMFVEVKDPDEKVILSRQYGSEGRFIFTSHTPGEHQICLHSNSSKFALFAGGMLRVHLDIQVGEHTNNYAEIAAKDKLTELQLRVRQLMEQVDQIQKEQNYQRYREERFRQTSESTNQRVLWWSIVQTLILVAIGFWQMRHLKSFFEAKKLV 223
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Zebrafish
Match: si:ch211-255i20.3 (si:ch211-255i20.3 [Source:ZFIN;Acc:ZDB-GENE-141216-113])

HSP 1 Score: 174.866 bits (442), Expect = 1.884e-53
Identity = 89/224 (39.73%), Postives = 145/224 (64.73%), Query Frame = 3 
Query:   51 FKIMNNCMTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVW--FGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            F +MN  +T     + L+ F++  +A+YF + E E KC IEE+P DT++ G ++ E +D++K    P    LG+ V + DP+ +VVL + +   G+F  T+ +SG+  +C+ SNS+ +  F G +L+VHL++Q GEH  D      KD +  ++  ++ LIDQ+  I+++Q++QR+RE +FR  SE TN  VL+++++Q  +L+ VGFWQM+NLK FF  KKLV
Sbjct:    4 FTVMNGSLT----GLLLASFVILASAMYFDLGEQEEKCIIEEIPVDTLVTGVFRLEYWDENKKSNTPQ---LGLTVTVRDPQHEVVLLKRFGRYGKFTFTSPASGQHFLCMQSNSTRFSVFAGDRLKVHLDVQMGEHTIDPNAAKTKDTIKAMEYNLQHLIDQMRYISRQQDFQREREEKFRQMSEETNGNVLWWAIIQTSILLSVGFWQMKNLKDFFIEKKLV 220
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Zebrafish
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:ZFIN;Acc:ZDB-GENE-030131-4915])

HSP 1 Score: 104.76 bits (260), Expect = 1.120e-26
Identity = 63/198 (31.82%), Postives = 111/198 (56.06%), Query Frame = 3 
Query:  126 AIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAK-LRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            +I F++     KC  EE+ +D ++ G+Y+      +K            +++ITD    ++  +  +++G+F  TT     F +C  S S +  G     +++L+++ G  A++Y+EIA  +KL  L++ +R+L D  E I  +  Y + RE   RDT+ESTN+RVLYFS+  +  L+ +  WQ+  L+ FF+AKKL+
Sbjct:   22 SISFYLPVRSRKCLREEIHKDVLVTGEYEISEQPNTKT-----------NLKITDSSGHILYVKEDATKGKFAFTTEDYDMFEVCFESKSPMGTGRVPDQQINLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKLI 208
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Zebrafish
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:ZFIN;Acc:ZDB-GENE-030131-4915])

HSP 1 Score: 104.76 bits (260), Expect = 1.120e-26
Identity = 63/198 (31.82%), Postives = 111/198 (56.06%), Query Frame = 3 
Query:  126 AIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAK-LRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            +I F++     KC  EE+ +D ++ G+Y+      +K            +++ITD    ++  +  +++G+F  TT     F +C  S S +  G     +++L+++ G  A++Y+EIA  +KL  L++ +R+L D  E I  +  Y + RE   RDT+ESTN+RVLYFS+  +  L+ +  WQ+  L+ FF+AKKL+
Sbjct:   22 SISFYLPVRSRKCLREEIHKDVLVTGEYEISEQPNTKT-----------NLKITDSSGHILYVKEDATKGKFAFTTEDYDMFEVCFESKSPMGTGRVPDQQINLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKLI 208
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Xenopus
Match: tmed4 (transmembrane p24 trafficking protein 4 [Source:NCBI gene;Acc:548496])

HSP 1 Score: 265.774 bits (678), Expect = 7.118e-89
Identity = 132/219 (60.27%), Postives = 167/219 (76.26%), Query Frame = 3 
Query:   66 NCMTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            +CM    + I    F L +  +YFHI ETE +CFIEE+P++TM++G YKT+++DK    ++P+  GLGMHVE+ D + KV+LSR Y SEGRF  T+H+ GE  ICLHSNS+   +F G KLRVHL+IQ GEH  +Y EIAAKDKLT+LQLRVRQL+DQVEQI KEQNYQR RE RFR TSESTN RVL++S+ Q  +L++ G WQM++LKSFF AKKLV
Sbjct:   13 SCMFLLLLGIL--QFGL-SRGLYFHIGETEKRCFIEEIPDETMVIGNYKTQLWDKQSETFLPSTPGLGMHVEVKDSDGKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSTRMSFFAGGKLRVHLDIQIGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRLTSESTNQRVLWWSIAQTLILILTGIWQMRHLKSFFEAKKLV 228
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Xenopus
Match: tmed9 (transmembrane p24 trafficking protein 9 [Source:NCBI gene;Acc:496564])

HSP 1 Score: 261.536 bits (667), Expect = 5.441e-87
Identity = 130/217 (59.91%), Postives = 161/217 (74.19%), Query Frame = 3 
Query:   72 MTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            M    + + L+       ++YFHI ETE KCFIEE+P++TM+VG Y+T++FDK +  Y+P   GLGM VE+ DP+ KV+LSR Y SEGRF  T+H+ GE  ICLHSNS+    F G  LRVHL+IQ GEHA DY +IAAKDKL  LQLRVRQLI+QVEQI KEQNYQR RE RFR TSEST+ RVL++S+ Q  +LV +G WQM++LK FF AKKLV
Sbjct:   25 MAAGGVLLLLAACFGPAFSLYFHIGETEKKCFIEEIPDETMVVGNYRTQMFDKQREDYLPATPGLGMFVEVKDPDDKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSTKFALFAGGMLRVHLDIQVGEHANDYVDIAAKDKLNTLQLRVRQLIEQVEQIQKEQNYQRWREERFRQTSESTSQRVLWWSIAQTLILVTIGVWQMKHLKGFFEAKKLV 241
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Xenopus
Match: thnsl1 (threonine synthase like 1 [Source:Xenbase;Acc:XB-GENE-982922])

HSP 1 Score: 173.326 bits (438), Expect = 7.602e-53
Identity = 87/210 (41.43%), Postives = 140/210 (66.67%), Query Frame = 3 
Query:   93 IFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            +FL  + L++ A+YFH+ E E KC IE++P +T++ G+YK + +D  ++ ++P+  GLGM V +T P  +V+LS+ Y  +G+F  T+HS GE  ICL SNS+  + F   KLR+H +IQ+GE+  D+  I AKDK+ ++   +  L  ++  I K+Q YQR+RE  +R  SE TN+ VL+++++Q  +L  VG WQ+++ K F  AKK+V
Sbjct:   10 MFLFFWPLSS-AMYFHVAEKEEKCLIEDLPSETLVTGRYKIQKWDLKEHDFLPSAPGLGMVVTVTAPNGEVLLSKLYGPDGKFTFTSHSPGEHTICLQSNSTNLIAFVSNKLRIHFDIQSGENPLDFHIINAKDKVKEVTYGLEHLRGEINHIIKQQEYQREREEHYRGKSEETNNNVLWWAIIQTAILTSVGIWQIKHFKDFLIAKKVV 218
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Xenopus
Match: shroom1 (shroom family member 1 [Source:Xenbase;Acc:XB-GENE-6492080])

HSP 1 Score: 109.768 bits (273), Expect = 2.122e-28
Identity = 66/201 (32.84%), Postives = 111/201 (55.22%), Query Frame = 3 
Query:  117 NTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNS-SVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
             T AI F++R    KC  EE+ +D ++ G+Y+           V    GL   +++TD    ++ S+  + +G+F  TT  +  + +C  S S S         + L+I+ G  A++YK++A  +KL  L++ +R+L D  + + K+ +Y + RE   RDT+EST+ RVLYFS   +  LV +  WQ+  L+ FF+AKKL+
Sbjct:   16 GTGAISFYLRPLGKKCLKEEIHKDVLVTGEYE-----------VSEQPGLTCDLKVTDSIGHILYSKEDARKGKFAFTTDDNDVYEVCFVSKSPSDTLSFTDQLIALDIKHGVEAKNYKDVAETEKLKPLEVELRRLEDLTQSVVKDFSYMKKREEEMRDTNESTSLRVLYFSAFSMFCLVALATWQVFYLRHFFKAKKLI 205
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Xenopus
Match: enpp7 (ectonucleotide pyrophosphatase/phosphodiesterase 7 [Source:Xenbase;Acc:XB-GENE-996993])

HSP 1 Score: 102.449 bits (254), Expect = 1.352e-25
Identity = 66/210 (31.43%), Postives = 113/210 (53.81%), Query Frame = 3 
Query:   93 IFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYK-TEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLR-VHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            +F  +F      I F +     KC  EE+ ++ ++ G+Y+ +E  ++ +           + ++ITD    ++ S+  +S+G+F  TT     F +C  S      G    + V+L ++ G  A++Y+EIA  +KL  L++ +R+L D  E I  +  Y + RE   RDT+ESTN RVLYFS+  +  L+ +  WQ+  L+ FF+AKKL+
Sbjct:    8 LFALLFCGYVQPISFSLPPNSRKCLREEIHKNVLVTGEYELSEAHNQGQ-----------VRLKITDSAGHILYSKEDASKGKFAFTTEEYDMFEVCFDSKLPAGAGRVPDQMVNLIMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNVRVLYFSIFSMCCLMGLATWQVFYLRRFFKAKKLI 206
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Mouse
Match: Tmed4 (transmembrane p24 trafficking protein 4 [Source:MGI Symbol;Acc:MGI:1915070])

HSP 1 Score: 271.552 bits (693), Expect = 2.487e-91
Identity = 131/213 (61.50%), Postives = 166/213 (77.93%), Query Frame = 3 
Query:   84 FISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            F  + L+V       +YFHI ETE +CFIEE+P++TM++G Y+T+++DK K V++P+  GLGMHVE+ DP+ KVVLSR Y SEGRF  T+H+ G+  ICLHSNS+    F G KLRVHL+IQ GEHA +Y EIAAKDKLT+LQLR RQL+DQVEQI KEQ+YQR RE RFR TSESTN RVL++S+ Q  +L++ G WQM++LKSFF AKKLV
Sbjct:   15 FGLLVLTVCAACARGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV 227
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Mouse
Match: Tmed9 (transmembrane p24 trafficking protein 9 [Source:MGI Symbol;Acc:MGI:1914761])

HSP 1 Score: 266.929 bits (681), Expect = 2.638e-89
Identity = 129/200 (64.50%), Postives = 161/200 (80.50%), Query Frame = 3 
Query:  123 NAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVW--FGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            +A+YFHI ETE KCFIEE+P++TM++G Y+T+++DK +  Y P   GLGM VE+ DPE KV+L+R Y SEGRF  T+H+ GE  ICLHSNS+ +  F G  LRVHL+IQ GEHA DY EIAAKDKL++LQLRVRQL++QVEQI KEQNYQR RE RFR TSESTN RVL++S++Q  +LV +G WQM++LKSFF AKKLV
Sbjct:   36 SALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPATPGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKLV 235
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Mouse
Match: Tmed9 (transmembrane p24 trafficking protein 9 [Source:MGI Symbol;Acc:MGI:1914761])

HSP 1 Score: 223.787 bits (569), Expect = 9.535e-73
Identity = 112/174 (64.37%), Postives = 137/174 (78.74%), Query Frame = 3 
Query:  201 GKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVW--FGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            G Y+T+++DK +  Y P   GLGM VE+ DPE KV+L+R Y SEGRF  T+H+ GE  ICLHSNS+ +  F G  LRVHL+IQ GEHA DY EIAAKDKL++LQLRVRQL++QVEQI KEQNYQR RE RFR TSESTN RVL++S++Q  +LV +G WQM++LKSFF AKKLV
Sbjct:   36 GNYRTQLYDKQREEYQPATPGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKLV 209
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Mouse
Match: Tmed4 (transmembrane p24 trafficking protein 4 [Source:MGI Symbol;Acc:MGI:1915070])

HSP 1 Score: 204.142 bits (518), Expect = 1.441e-65
Identity = 97/164 (59.15%), Postives = 120/164 (73.17%), Query Frame = 3 
Query:   84 FISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQR 569
            F  + L+V       +YFHI ETE +CFIEE+P++TM+        +DK K V++P+  GLGMHVE+ DP+ KVVLSR Y SEGRF  T+H+ G+  ICLHSNS+    F G KLRVHL+IQ GEHA +Y EIAAKDKLT+LQLR RQL+DQVEQI KEQ+YQR
Sbjct:   15 FGLLVLTVCAACARGLYFHIGETEKRCFIEEIPDETMM--------WDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQR 170
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Mouse
Match: Tmed11 (transmembrane p24 trafficking protein 11 [Source:MGI Symbol;Acc:MGI:1914616])

HSP 1 Score: 191.43 bits (485), Expect = 5.001e-60
Identity = 101/218 (46.33%), Postives = 145/218 (66.51%), Query Frame = 3 
Query:   69 CMTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            C +F+F           + A YFH  E E KC IE++P DT+I G +K + +D  ++ ++ +  GLGM V +T    +V+LS+ Y ++G F  T+HSSGE  ICL SNS+  V FGG+KLR+HL+I+ GEH  D   + AKDK+ ++  +++ LI+QVEQI KEQ+YQRDRE  FR TSE TN  VL+++  Q+ + + VG +QM++LK FF AKKLV
Sbjct:    9 CFSFSF-----------SAAFYFHAGEREEKCIIEDIPSDTLITGTFKVQQWDIVRHDFLESAPGLGMFVTVTTYNDEVLLSKLYGAQGTFYFTSHSSGEHIICLESNSTQFVSFGGSKLRIHLDIRVGEHDLDAAIVQAKDKVNEVTFKLQHLIEQVEQILKEQDYQRDREENFRITSEDTNRNVLWWAFAQILIFISVGIFQMKHLKDFFIAKKLV 215
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. UniProt/SwissProt
Match: sp|Q8R1V4|TMED4_MOUSE (Transmembrane emp24 domain-containing protein 4 OS=Mus musculus OX=10090 GN=Tmed4 PE=1 SV=1)

HSP 1 Score: 271.552 bits (693), Expect = 1.740e-90
Identity = 131/213 (61.50%), Postives = 166/213 (77.93%), Query Frame = 3 
Query:   84 FISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            F  + L+V       +YFHI ETE +CFIEE+P++TM++G Y+T+++DK K V++P+  GLGMHVE+ DP+ KVVLSR Y SEGRF  T+H+ G+  ICLHSNS+    F G KLRVHL+IQ GEHA +Y EIAAKDKLT+LQLR RQL+DQVEQI KEQ+YQR RE RFR TSESTN RVL++S+ Q  +L++ G WQM++LKSFF AKKLV
Sbjct:   15 FGLLVLTVCAACARGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV 227
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. UniProt/SwissProt
Match: sp|B3NZM5|TMEDE_DROER (Transmembrane emp24 domain-containing protein eca OS=Drosophila erecta OX=7220 GN=eca PE=3 SV=1)

HSP 1 Score: 270.781 bits (691), Expect = 2.577e-90
Identity = 132/212 (62.26%), Postives = 169/212 (79.72%), Query Frame = 3 
Query:   84 FISIFLSVFILNTN-AIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            FIS+ L + IL++   +YFHI ETE KCFIEEVP++T ++  YK E++D   N ++P+  G+GMHVE+ D + K+VLSR YSS+GR   T+H+ GE  IC++SNS+ WF GA+LRVHL+IQ GEHA DY  +A K+KLT+LQLR+RQL+DQVEQITKEQNYQR RE RFR TSESTNSRVL++SL Q  +LV +GFWQM++LKSFF AKKLV
Sbjct:    5 FISLALMLCILHSACGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMYSNSTAWFSGAQLRVHLDIQVGEHAIDYANVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMRHLKSFFEAKKLV 216
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. UniProt/SwissProt
Match: sp|B4PVC6|TMEDE_DROYA (Transmembrane emp24 domain-containing protein eca OS=Drosophila yakuba OX=7245 GN=eca PE=3 SV=1)

HSP 1 Score: 270.396 bits (690), Expect = 4.447e-90
Identity = 131/212 (61.79%), Postives = 169/212 (79.72%), Query Frame = 3 
Query:   84 FISIFLSVFILNTN-AIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            FIS+ L + +L++   +YFHI ETE KCFIEEVP++T ++  YK E++D   N ++P+  G+GMHVE+ D + K+VLSR YSS+GR   T+H+ GE  IC++SNS+ WF GA+LRVHL+IQ GEHA DY  +A K+KLT+LQLR+RQL+DQVEQITKEQNYQR RE RFR TSESTNSRVL++SL Q  +LV +GFWQM++LKSFF AKKLV
Sbjct:    5 FISLALMLCVLHSACGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMYSNSTAWFSGAQLRVHLDIQVGEHAIDYANVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMRHLKSFFEAKKLV 216
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. UniProt/SwissProt
Match: sp|Q7Z7H5|TMED4_HUMAN (Transmembrane emp24 domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TMED4 PE=1 SV=1)

HSP 1 Score: 270.011 bits (689), Expect = 8.371e-90
Identity = 128/202 (63.37%), Postives = 161/202 (79.70%), Query Frame = 3 
Query:  117 NTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
                +YFHI ETE +CFIEE+P++TM++G Y+T+++DK K V++P+  GLGMHVE+ DP+ KVVLSR Y SEGRF  T+H+ G+  ICLHSNS+    F G KLRVHL+IQ GEHA +Y EIAAKDKLT+LQLR RQL+DQVEQI KEQ+YQR RE RFR TSESTN RVL++S+ Q  +L++ G WQM++LKSFF AKKLV
Sbjct:   26 GAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV 227
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. UniProt/SwissProt
Match: sp|Q9I7K5|TMEDE_DROME (Transmembrane emp24 domain-containing protein eca OS=Drosophila melanogaster OX=7227 GN=eca PE=2 SV=2)

HSP 1 Score: 268.085 bits (684), Expect = 2.781e-89
Identity = 131/212 (61.79%), Postives = 168/212 (79.25%), Query Frame = 3 
Query:   84 FISIFLSVFILNTN-AIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            FIS+ L + +L++   +YFHI ETE KCFIEEVP++T ++  YK E++D   N ++P+  G+GMHVE+ D + K+VLSR YSS+GR   T+H+ GE  IC+ SNS+ WF GA+LRVHL+IQ GEHA DY  +A K+KLT+LQLR+RQL+DQVEQITKEQNYQR RE RFR TSESTNSRVL++SL Q  +LV +GFWQM++LKSFF AKKLV
Sbjct:    5 FISLALILCVLHSACGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMRHLKSFFEAKKLV 216
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. TrEMBL
Match: A0A267ES54 (GOLD domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005649g2 PE=3 SV=1)

HSP 1 Score: 304.294 bits (778), Expect = 6.367e-101
Identity = 146/213 (68.54%), Postives = 177/213 (83.10%), Query Frame = 3 
Query:   78 FTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            F +  +FL    +  NA+YFHI ETE+KCFIEE+PEDT++VGKYK EIFDK +N +VPTVSGLGMHVEI DP++K+VLSRTYS +G+F  T+H+SGE  ICLHSNSS WF   +LRVHL+IQ GEHAQDY  IAAKDKLTDL+LRVRQL+DQVEQI+KEQNYQR RE  FR  SESTN RVL++S++Q  +L+  GFWQM++LKSFF+AKKLV
Sbjct:    8 FLYSFLFLCFLSVGGNALYFHIGETETKCFIEEIPEDTLLVGKYKVEIFDKGQNKFVPTVSGLGMHVEIKDPDRKMVLSRTYSDQGQFSFTSHTSGEHTICLHSNSSAWFNSGQLRVHLDIQVGEHAQDYYAIAAKDKLTDLELRVRQLLDQVEQISKEQNYQRHREEVFRHISESTNQRVLWWSILQTVILLGTGFWQMRHLKSFFQAKKLV 220
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. TrEMBL
Match: A0A267F105 (GOLD domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005649g1 PE=3 SV=1)

HSP 1 Score: 303.523 bits (776), Expect = 1.149e-100
Identity = 146/213 (68.54%), Postives = 177/213 (83.10%), Query Frame = 3 
Query:   78 FTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            F +  +FL    +  NA+YFHI ETE+KCFIEE+PEDT++VGKYK EIFDK +N +VPTVSGLGMHVEI DP++K+VLSRTYS +G+F  T+H+SGE  ICLHSNSS WF   +LRVHL+IQ GEHAQDY  IAAKDKLTDL+LRVRQL+DQVEQI+KEQNYQR RE  FR  SESTN RVL++S++Q  +L+  GFWQM++LKSFF+AKKLV
Sbjct:    8 FLYSFLFLCFLSVAGNALYFHIGETETKCFIEEIPEDTLLVGKYKVEIFDKGQNKFVPTVSGLGMHVEIKDPDRKMVLSRTYSDQGQFSFTSHTSGEHTICLHSNSSAWFNSGQLRVHLDIQVGEHAQDYYAIAAKDKLTDLELRVRQLLDQVEQISKEQNYQRHREEVFRHISESTNQRVLWWSILQTVILLGTGFWQMRHLKSFFQAKKLV 220
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. TrEMBL
Match: A0A1I8HRM9 (GOLD domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 299.671 bits (766), Expect = 2.247e-99
Identity = 143/201 (71.14%), Postives = 172/201 (85.57%), Query Frame = 3 
Query:  114 LNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            +  NA+YFHI ETE+KCFIEE+PEDT++VGKYK EIFDK +N +VPTVSGLGMHVEI DP++K+VLSRTYS +G+F  T+H+SGE  ICLHSNSS WF   +LRVHL+IQ GEHAQDY  IAAKDKLTDL+LRVRQL+DQVEQI+KEQNYQR RE  FR  SESTN RVL++S++Q  +L+  GFWQM++LKSFF+AKKLV
Sbjct:    1 VGGNALYFHIGETETKCFIEEIPEDTLLVGKYKVEIFDKGQNKFVPTVSGLGMHVEIKDPDRKMVLSRTYSDQGQFSFTSHTSGEHTICLHSNSSAWFNSGQLRVHLDIQVGEHAQDYYAIAAKDKLTDLELRVRQLLDQVEQISKEQNYQRHREEVFRHISESTNQRVLWWSILQTVILLGTGFWQMRHLKSFFQAKKLV 201
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. TrEMBL
Match: A0A1S3K627 (transmembrane emp24 domain-containing protein eca-like OS=Lingula unguis OX=7574 GN=LOC106179102 PE=3 SV=1)

HSP 1 Score: 295.819 bits (756), Expect = 1.247e-97
Identity = 137/197 (69.54%), Postives = 168/197 (85.28%), Query Frame = 3 
Query:  126 AIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
             +YFHI ETE KCFIEE+P++TM+VG YK EIFD+S+N ++PT  GLGMHVE+ DP++KV+LSRTY+S+GR+  T+H++GE  ICLHSNSS WFGG +LRVHL+IQ GEHA DY +IA KDKLT+LQLRVRQL+DQVEQITKEQNYQR RE RFR TSESTN RVL++S+ Q  +L+V GFWQM++LK FF AKKLV
Sbjct:   22 GLYFHIGETEKKCFIEEIPDETMVVGNYKVEIFDRSQNAFLPTGGGLGMHVEVKDPDEKVILSRTYASDGRYTFTSHTAGEHTICLHSNSSAWFGGGQLRVHLDIQVGEHANDYPQIATKDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLVLLVTGFWQMRHLKGFFEAKKLV 218
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. TrEMBL
Match: A0A1S3HQP8 (transmembrane emp24 domain-containing protein eca OS=Lingula unguis OX=7574 GN=LOC106157295 PE=3 SV=1)

HSP 1 Score: 295.819 bits (756), Expect = 1.317e-97
Identity = 137/197 (69.54%), Postives = 168/197 (85.28%), Query Frame = 3 
Query:  126 AIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
             +YFHI ETE KCFIEE+P++TM+VG YK EIFD+S+N ++PT  GLGMHVE+ DP++KV+LSRTY+S+GR+  T+H++GE  ICLHSNSS WFGG +LRVHL+IQ GEHA DY +IA KDKLT+LQLRVRQL+DQVEQITKEQNYQR RE RFR TSESTN RVL++S+ Q  +L+V GFWQM++LK FF AKKLV
Sbjct:   22 GLYFHIGETEKKCFIEEIPDETMVVGNYKVEIFDRSQNAFLPTGGGLGMHVEVKDPDEKVILSRTYASDGRYTFTSHTAGEHTICLHSNSSAWFGGGQLRVHLDIQVGEHANDYPQIATKDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLVLLVTGFWQMRHLKGFFEAKKLV 218
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Cavefish
Match: tmed4 (transmembrane p24 trafficking protein 4 [Source:ZFIN;Acc:ZDB-GENE-040625-140])

HSP 1 Score: 272.707 bits (696), Expect = 7.390e-92
Identity = 130/210 (61.90%), Postives = 162/210 (77.14%), Query Frame = 3 
Query:   93 IFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            + L  +   + A+YFHI ETE KCFIEE+P++TM++GKY+T+++DK    ++P   GLGMHVEI DP+ KV+LSR Y S+GRF  T+H+ GE  ICLHSNS+    F G KLRVHL+IQ GEH  +Y EIAAKDKLT+LQLRVRQL+DQVEQI KEQNYQR RE RFR TSESTN RVL++S+ Q  +L+    WQM++LKSFF AKKLV
Sbjct:   17 LLLFAWFSPSRALYFHIGETEKKCFIEEIPDETMVIGKYRTQLWDKQTGSFLPATPGLGMHVEIKDPDTKVILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGKLRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSIAQTIILITAAIWQMRHLKSFFEAKKLV 226
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Cavefish
Match: tmed9 (transmembrane p24 trafficking protein 9 [Source:NCBI gene;Acc:103030438])

HSP 1 Score: 271.166 bits (692), Expect = 3.077e-91
Identity = 135/218 (61.93%), Postives = 171/218 (78.44%), Query Frame = 3 
Query:   72 MTFTFISIFLSVFILN-TNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVW--FGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            M FT  ++ +  F  +  +A+YFHI ETE KCFIEE+P++TMI+G Y+T+++DK K  Y+P   GLGM VE+ DP++KV+LSR Y SEGRF  T+H+ GE  ICLHSNSS +  F G  LRVHL+IQ GEH  +Y+ IAAKDKLT+LQLRVRQL++QV+QI KEQNYQR RE RFR TSESTN RVL++S+VQ  +LV +GFWQM++LKSFF AKKLV
Sbjct:    6 MQFTLCTVLVLNFCYSLVSALYFHIGETEKKCFIEEIPDETMIIGNYRTQLYDKQKEEYLPATQGLGMFVEVKDPDEKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSSKFSLFAGGMLRVHLDIQVGEHTNNYEVIAAKDKLTELQLRVRQLVEQVDQIQKEQNYQRYREERFRQTSESTNQRVLWWSIVQTLILVAIGFWQMRHLKSFFEAKKLV 223
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Cavefish
Match: tmed9 (transmembrane p24 trafficking protein 9 [Source:NCBI gene;Acc:103030438])

HSP 1 Score: 270.781 bits (691), Expect = 5.013e-91
Identity = 135/218 (61.93%), Postives = 171/218 (78.44%), Query Frame = 3 
Query:   72 MTFTFISIFLSVFILN-TNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVW--FGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            M FT  ++ +  F  +  +A+YFHI ETE KCFIEE+P++TMI+G Y+T+++DK K  Y+P   GLGM VE+ DP++KV+LSR Y SEGRF  T+H+ GE  ICLHSNSS +  F G  LRVHL+IQ GEH  +Y+ IAAKDKLT+LQLRVRQL++QV+QI KEQNYQR RE RFR TSESTN RVL++S+VQ  +LV +GFWQM++LKSFF AKKLV
Sbjct:   15 MQFTLCTVLVLNFCYSLVSALYFHIGETEKKCFIEEIPDETMIIGNYRTQLYDKQKEEYLPATQGLGMFVEVKDPDEKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSSKFSLFAGGMLRVHLDIQVGEHTNNYEVIAAKDKLTELQLRVRQLVEQVDQIQKEQNYQRYREERFRQTSESTNQRVLWWSIVQTLILVAIGFWQMRHLKSFFEAKKLV 232
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Cavefish
Match: si:ch211-255i20.3 (transmembrane emp24 domain-containing protein 11-like [Source:NCBI gene;Acc:103034721])

HSP 1 Score: 162.155 bits (409), Expect = 1.989e-48
Identity = 85/217 (39.17%), Postives = 140/217 (64.52%), Query Frame = 3 
Query:   72 MTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVW--FGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            M  ++  +  + F+  + A+YF + +   KC IEE+PED ++ G +  E +D+ K    P    LG+ V + DP  +V+L + +   G+F  T+H+SG+  +C+ SNS+ +  F G +L+VHL++Q GEH  D     AK+    ++ R++ LIDQ++ I+K+Q++QR+RE  FR+ SE+TN  VL+++L+Q  +L+ VGFWQM+NLK+F   KKLV
Sbjct:   19 MKLSWCYLLAACFVSLSFAMYFDLVDQREKCIIEEIPEDVLVTGYFFVEHWDEKKQDNSP---HLGVTVTVRDPNNEVLLMKRFGRYGKFTFTSHASGQHFLCVKSNSTRFSAFAGERLKVHLDVQMGEHTIDPSAEKAKETFKTMEYRMQHLIDQMQYISKQQDFQREREELFREMSETTNGSVLWWALIQTSILLTVGFWQMRNLKNFLIEKKLV 232
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Cavefish
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:NCBI gene;Acc:103042340])

HSP 1 Score: 105.145 bits (261), Expect = 6.518e-27
Identity = 67/208 (32.21%), Postives = 114/208 (54.81%), Query Frame = 3 
Query:   96 FLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLR-VHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            F SVF     +I F +     KC  EE+ +D ++ G+Y+           +        +++ITD    ++ S+  +++G+F  TT     F +C  S S +  G    + ++L+++ G  A++Y+EIA  +KL  L++ +R+L D  E I  +  Y + RE   RDT+ESTN+RVLYFS+  +  L+ +  WQ+  L+ FF+AKKL+
Sbjct:   14 FDSVF-----SISFFLPVRTRKCLKEEIHKDVLVTGEYE-----------ISEQPNTKTNLKITDSSGHILYSKEDATKGKFAFTTEDYDMFEVCFESKSQMGTGRVPDQLINLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKLI 205
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001929.1 (pep scaffold:Pmarinus_7.0:GL476868:73855:89088:-1 gene:ENSPMAG00000001745.1 transcript:ENSPMAT00000001929.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 234.187 bits (596), Expect = 3.523e-78
Identity = 115/175 (65.71%), Postives = 140/175 (80.00%), Query Frame = 3 
Query:  198 VGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
             G YKT+++DK+K  ++P+  GLGMHVE+ DP+ KV+LS+ YSSEGRF  T+H+ GE  ICLHSNS+    F G +LRVHL+IQ GEHA DY EIAAKDKLT+LQLRVRQL+DQVEQI KEQNYQR RE RFR TSESTN RVL++S+ Q  +L+  G WQM++LKSFF AKKLV
Sbjct:    2 TGNYKTQLWDKNKQEFLPSTPGLGMHVEVKDPDGKVILSKQYSSEGRFTFTSHTPGEHQICLHSNSTKIALFAGGRLRVHLDIQVGEHANDYSEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLILITTGIWQMRHLKSFFEAKKLV 176
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Sea Lamprey
Match: tmed2 (transmembrane p24 trafficking protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-269])

HSP 1 Score: 50.8322 bits (120), Expect = 2.269e-8
Identity = 39/149 (26.17%), Postives = 69/149 (46.31%), Query Frame = 3 
Query:  276 VEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGE--HAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            V+IT P+ + +      S G++    H  G +  C  +  S         V   I  GE    QD +  A ++KL ++   + +L   +  +  EQ Y   RE   R  +++TNSRV+ ++  +  +LV +   Q+  LK FF  +++V
Sbjct:    1 VQITGPDGREIYRGDRESNGKYTFAAHMDGVYKFCFGNKMSTM---TPKMVMFTIDMGETPKGQDMETEAHQNKLEEM---INELATAMTAVKHEQEYMEVRERIHRSVNDNTNSRVVLWAFFEALVLVAMTLGQIYYLKRFFEVRRVV 143
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Yeast
Match: ERP6 (Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; ERP6 has a paralog, ERP1, that arose from the whole genome duplication [Source:SGD;Acc:S000002970])

HSP 1 Score: 110.923 bits (276), Expect = 6.458e-30
Identity = 72/214 (33.64%), Postives = 122/214 (57.01%), Query Frame = 3 
Query:   93 IFLSVFIL--NTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFD-KSKNVYVPTVSGLGMHV---EITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            IFL+  +L    +A YF+    + KCF++E+ +DT++ G Y  E++D K  +  +P+ +  G+ +   E+ D   +VV  +  S  G F      SGE+ ICL S  + W G  K ++ +E + G  A    ++  K+ L  L  +V  L  ++  I +EQ   R+RE  FRD SES NSR +++++ QV LL+++  WQM++L+SFF  +K++
Sbjct:    6 IFLAFVLLPFRVSAFYFYGYGGDRKCFLKELSKDTLLKGSYNLEVYDDKLADYALPSYNDYGIVIDVEEVFDNNHRVVHQQG-SPSGDFSFLALESGEYKICLQSRVNNWVGKTKTKLEIEFEVGFEAM--LDMQRKETLESLHGKVSILNSKIVDIRREQQLMREREESFRDISESVNSRAMWWTVTQVTLLIIICVWQMKSLRSFFVKQKVL 216
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Yeast
Match: ERP1 (Member of the p24 family involved in ER to Golgi transport; role in misfolded protein quality control; forms heterotrimeric complex with Erp2p, Emp24p, and Erv25p; localized to COPII-coated vesicles; ERP1 has a paralog, ERP6, that arose from the whole genome duplication [Source:SGD;Acc:S000002129])

HSP 1 Score: 98.2117 bits (243), Expect = 4.044e-25
Identity = 62/217 (28.57%), Postives = 110/217 (50.69%), Query Frame = 3 
Query:   81 TFISIFLSVFIL--NTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVS---GLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            + + +F    +L     A Y++    E KCF +E+ + T+    YK +I+D     Y    +   G+ + +E T  +  +V+ +  S+ G        SGE  IC+   +  W   AK ++ +E Q G  + +  +   K  +  L  +V  L  ++ +I +EQ   RDREA FRD SE+ NSR +++ ++Q+ +L V   WQM++L  FF  +K++
Sbjct:    5 SLLQVFACCLVLPAQVTAFYYYTSGAERKCFHKELSKGTLFQATYKAQIYDDQLQNYRDAGAQDFGVLIDIEETFDDNHLVVHQKGSASGDLTFLASDSGEHKICIQPEAGGWLIKAKTKIDVEFQVG--SDEKLDSKGKATIDILHAKVNVLNSKIGEIRREQKLMRDREATFRDASEAVNSRAMWWIVIQLIVLAVTCGWQMKHLGKFFVKQKIL 219
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Yeast
Match: ERV25 (Member of the p24 family involved in ER to Golgi transport; role in misfolded protein quality control; forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, [Source:SGD;Acc:S000004473])

HSP 1 Score: 79.7221 bits (195), Expect = 2.322e-18
Identity = 42/134 (31.34%), Postives = 80/134 (59.70%), Query Frame = 3 
Query:  315 RTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            R ++ + R   T  SS  F +C  + +          + L+I++G  A+D+ +I+A +KL  +++ +R++ +  ++I  E  Y ++RE R RDT+ESTN RV  FS++ + +L  +G WQ+  LK++F+ K ++
Sbjct:   78 RDFAGDVRVAFTAPSSTAFDVCFENQAQYRGRSLSRAIELDIESGAEARDWNKISANEKLKPIEVELRRVEEITDEIVDELTYLKNREERLRDTNESTNRRVRNFSILVIIVLSSLGVWQVNYLKNYFKTKHII 211
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Yeast
Match: ERP5 (Protein with similarity to Emp24p and Erv25p; member of the p24 family involved in ER to Golgi transport [Source:SGD;Acc:S000001152])

HSP 1 Score: 75.485 bits (184), Expect = 9.297e-17
Identity = 62/202 (30.69%), Postives = 106/202 (52.48%), Query Frame = 3 
Query:  123 NAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICL---HSNSSVWFGGAKLRVHLEIQTGE-HAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
             A++F+ +  E+KCF E +    +++G     + +K         S L + V+ T      VL++  S  G    T   +GE   C    +S  S     A LRV +E++ G   A D K+   K+ +  L+ RV QL  ++  I KEQ+  R++EA FR+ SES NS+++ +S+ Q+ +L+    +Q++ LK+FF  +K+V
Sbjct:   20 GAVHFYAKSGETKCFYEHLSRGNLLIGDLDLYV-EKDGLFEEDPESSLTITVDETFDNDHRVLNQKNSHTGDVTFTALDTGEHRFCFTPFYSKKS-----ATLRVFIELEIGNVEALDSKK---KEDMNSLKGRVGQLTQRLSSIRKEQDAIREKEAEFRNQSESANSKIMTWSVFQLLILLGTCAFQLRYLKNFFVKQKVV 212
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Nematostella
Match: EDO35953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK51])

HSP 1 Score: 274.248 bits (700), Expect = 4.227e-93
Identity = 126/209 (60.29%), Postives = 168/209 (80.38%), Query Frame = 3 
Query:   96 FLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVW--FGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            F+   + N  A+YFH+ ETE KCFIEE+P++TM++GKYKT+++D++   ++P+  G+GMHVE+ DP  K+++S+ YSSEGRF  T+H+ GE  ICLHSNS+ W  + G +LR+HL+IQ GEHA DY +IAAKDKLT+LQLR+RQL+DQVEQI+KEQNYQR RE RFR TSESTN RVL+++L Q  +L+  GFWQM++LK FF AKKLV
Sbjct:    9 FIGYMLGNVQALYFHMGETEKKCFIEEIPDETMVIGKYKTQLYDENIKDFLPSSPGIGMHVEVKDPNGKIIMSKYYSSEGRFTFTSHTPGEHVICLHSNSTRWSLWAGGRLRIHLDIQVGEHANDYAQIAAKDKLTELQLRIRQLLDQVEQISKEQNYQRFREERFRMTSESTNQRVLWWALAQTVILLATGFWQMRHLKGFFEAKKLV 217
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Nematostella
Match: EDO41239 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z3])

HSP 1 Score: 105.145 bits (261), Expect = 2.151e-27
Identity = 63/215 (29.30%), Postives = 115/215 (53.49%), Query Frame = 3 
Query:   72 MTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            +T   + + +  +IL+ +++ F +     KC  EEV +D ++ G++      + K            ++++TD    V   R  +++G+F  TT     + +C  S +S   GG+   V + I+ G  A++Y+++A  +KL  +++ +++L D  + I  +  Y R RE   RDT+EST+SRVLYFS+  +  L  +  WQ+  L+ FF AKKL+
Sbjct:    4 ITVLLVPLLICEYILSASSLSFTLSSGNRKCLKEEVHKDVLVTGEFTLSDAPQQKT-----------NLKVTDSTGHVFYKRDDATKGKFAFTTDDYDMYEVCFDSETSHG-GGSDREVSINIKHGVEAKNYEDLAKAEKLKPMEVELKRLEDLGDAIVNDFAYMRQREQEMRDTNESTHSRVLYFSIFSILCLFGLATWQLFYLRRFFIAKKLI 206
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Nematostella
Match: EDO41240 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z4])

HSP 1 Score: 62.003 bits (149), Expect = 4.198e-11
Identity = 51/200 (25.50%), Postives = 93/200 (46.50%), Query Frame = 3 
Query:  117 NTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            NTN+  F I+    KC  +   +D +    Y+    D+S  V +  +          D   +++ ++  +++G+F  T    G F +C  +   +  G   + V L+I+ G  A++Y+ +A   KL   ++ V +L D   ++        +R      T+EST +R+LY  +    LLV++   Q+  L  FF AKKL+
Sbjct:  143 NTNS--FKIKAATRKCLTDFAQKDQLFKADYEIS-HDQSSTVKITVID--------IDVTLQLLFTKENATKGKFAFTFDRDGHFDLCFDNQVRLGSGSDSI-VFLKIKRGSEAKNYENLALAQKLQPQEIEVMRLADMSSEVLTSLGRLINRGEDHLITNESTGARILYLGVFLTMLLVMLTGGQLVYLHRFFAAKKLI 330

HSP 2 Score: 52.7582 bits (125), Expect = 4.768e-8
Identity = 29/110 (26.36%), Postives = 56/110 (50.91%), Query Frame = 3 
Query:  270 MHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTS 599
            M +++ D    ++     + +G+F  TT  +  + +C   NS    G  +  V + I+ G  A+ Y+ +A  +KL  ++L +R+L D  ++I     Y R+RE   R+T+
Sbjct:   37 MRIQVLDTANHILYKNDDARKGKFAITTSENNYYEVCFKDNSPGQ-GAVRREVSINIKHGTEAKAYQNLAQAEKLKPIKLAMRRLEDMADEIVSSFAYFREREEEQRNTN 145
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Nematostella
Match: EDO31547 (Transmembrane emp24 domain-containing protein [Source:UniProtKB/Swiss-Prot;Acc:A7SXK3])

HSP 1 Score: 60.077 bits (144), Expect = 6.433e-11
Identity = 52/209 (24.88%), Postives = 96/209 (45.93%), Query Frame = 3 
Query:   90 SIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            S  + +F+  ++  YF   +       EE   D +  G     IF+ ++  +      L + V+I  P++KV+ S    + G++    H  G +  C  SN         L+  ++I         ++ A  DKL+++   V QL + +  +  EQ Y   RE   R  +++TNSRV+++S  +  +LV +   Q+  LK FF  +++V
Sbjct:    9 SCIVLMFLARSSLCYFITIDAHG----EECFHDKVTSGTKMGLIFEVAEGGF------LDIDVKIIGPDQKVIYSGERETSGKYTFAAHMDGTYNYCF-SNKMSTMTPKVLKFSMDIGEAPKDTSKEDNAGHDKLSEM---VSQLSEAMTGVKHEQEYMEVRERIHRSINDNTNSRVVWWSFFESLVLVAMTLGQVYYLKRFFEVRRVV 203
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Medaka
Match: tmed4 (transmembrane emp24 domain-containing protein 4 [Source:NCBI gene;Acc:101175398])

HSP 1 Score: 274.248 bits (700), Expect = 1.110e-92
Identity = 132/211 (62.56%), Postives = 166/211 (78.67%), Query Frame = 3 
Query:   90 SIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            S  L  +I + +A+YFHI ETE KCFIEE+P++TM++GKY+T+++DK    ++P   GLGMHVEI DP+ K++LSR Y S+GRF  T+H+ GE  ICLHSNS+    F G KLRVHL+IQ GEH  +Y EIAAKDKLT+LQLRVRQL+DQVEQI KEQNYQR RE RFR TSESTN RVL++S+ Q  +L++ G WQM++LKSFF AKKLV
Sbjct:    4 SFLLLSWISSISALYFHIGETEKKCFIEEIPDETMVIGKYRTQLWDKQSGSFLPATPGLGMHVEIKDPDTKIILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGKLRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSITQTLILIITGIWQMKHLKSFFEAKKLV 214
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Medaka
Match: tmed4 (transmembrane emp24 domain-containing protein 4 [Source:NCBI gene;Acc:101175398])

HSP 1 Score: 273.863 bits (699), Expect = 1.784e-92
Identity = 131/211 (62.09%), Postives = 166/211 (78.67%), Query Frame = 3 
Query:   90 SIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSS--VWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            +  L  +I + +A+YFHI ETE KCFIEE+P++TM++GKY+T+++DK    ++P   GLGMHVEI DP+ K++LSR Y S+GRF  T+H+ GE  ICLHSNS+    F G KLRVHL+IQ GEH  +Y EIAAKDKLT+LQLRVRQL+DQVEQI KEQNYQR RE RFR TSESTN RVL++S+ Q  +L++ G WQM++LKSFF AKKLV
Sbjct:    9 AFLLLSWISSISALYFHIGETEKKCFIEEIPDETMVIGKYRTQLWDKQSGSFLPATPGLGMHVEIKDPDTKIILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGKLRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSITQTLILIITGIWQMKHLKSFFEAKKLV 219
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Medaka
Match: tmed9 (transmembrane emp24 domain-containing protein 9 [Source:NCBI gene;Acc:101173315])

HSP 1 Score: 265.003 bits (676), Expect = 5.540e-89
Identity = 132/205 (64.39%), Postives = 162/205 (79.02%), Query Frame = 3 
Query:  108 FILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVW--FGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            F     A+YFHI E E KCFIEE+P++TMI+G Y+T+++DK K  Y+P   GLGM VE+ DP++KV+LSR Y SEGRF  T+H+ GE  ICLHSNSS +  F G  LRVHL+IQ GEHA +Y EIAAKDKLT+LQLRVRQL++QV+QI KEQNYQR RE RFR TSESTN RVL++S+VQ  +LV +G WQM++LKSFF AKKLV
Sbjct:   14 FCSRAPALYFHIGELEKKCFIEEIPDETMIIGNYRTQLYDKQKEEYLPASPGLGMFVEVKDPDEKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSSKFSLFVGGTLRVHLDIQVGEHANNYAEIAAKDKLTELQLRVRQLVEQVDQIQKEQNYQRYREERFRQTSESTNQRVLWWSIVQTLILVAIGIWQMRHLKSFFEAKKLV 218
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Medaka
Match: si:ch211-255i20.3 (transmembrane emp24 domain-containing protein 11-like [Source:NCBI gene;Acc:101164569])

HSP 1 Score: 149.828 bits (377), Expect = 6.124e-44
Identity = 84/210 (40.00%), Postives = 132/210 (62.86%), Query Frame = 3 
Query:   93 IFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVW--FGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            + LS  +L+  A+YF + E E KC IEE+PEDT++ G +    ++ +   + P    LG+ V + D  +KVV+S+ Y   G+F  T H SG+  +C  +NS+ +  F   K+++HL++Q GEH+ D      KD L  L+  +  + +Q+  I+++Q YQR++E  FR  SE TNS+V+++++VQ  LL+ VGFWQM+ LK FF AKKLV
Sbjct:    9 VLLSYLMLSA-AMYFQLGEQEEKCIIEEIPEDTLVKGHFLLVPWNPNMPSHSP---HLGVTVTVKDQNQKVVMSKRYGKLGKFTFTAHMSGQHYLCFQTNSTRFSVFAAEKMKLHLDVQMGEHSIDPSVQMTKDNLEVLEESLMHMREQMTYISRQQEYQREKEELFRQISEDTNSKVVWWAVVQTSLLLCVGFWQMKRLKDFFIAKKLV 214
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Medaka
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:NCBI gene;Acc:101167507])

HSP 1 Score: 107.457 bits (267), Expect = 9.653e-28
Identity = 67/198 (33.84%), Postives = 111/198 (56.06%), Query Frame = 3 
Query:  126 AIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLR-VHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            +I F +     KC  EE+ +D ++ G+Y     D ++     T      H++ITD     + S+  +++G+F  TT     F +C  S S +  G    + V+L+++ G  A++Y+EIA  +KL  L++ +R+L D  E I  +  Y + RE   RDT+ESTN+RVLYFS+  +  L+ +  WQ+  L+ FF+AKKL+
Sbjct:   20 SISFFLPVNSRKCLREEIHKDVLVTGEY-----DLTEQPNTKT------HLKITDSSTHTLYSKEDATKGKFAFTTEDYDMFEVCFESKSPLGTGRVPDQLVNLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKLI 206
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Planmine SMEST
Match: SMESG000073800.1 (SMESG000073800.1)

HSP 1 Score: 430.639 bits (1106), Expect = 2.208e-154
Identity = 219/219 (100.00%), Postives = 219/219 (100.00%), Query Frame = 3 
Query:   60 MNNCMTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            MNNCMTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSLVQVGLLVVVGFWQMQNLKSFFRAKKLV
Sbjct:    1 MNNCMTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSLVQVGLLVVVGFWQMQNLKSFFRAKKLV 219
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Planmine SMEST
Match: SMESG000073800.1 (SMESG000073800.1)

HSP 1 Score: 419.853 bits (1078), Expect = 2.856e-150
Identity = 215/215 (100.00%), Postives = 215/215 (100.00%), Query Frame = 3 
Query:   72 MTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            MTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSLVQVGLLVVVGFWQMQNLKSFFRAKKLV
Sbjct:    1 MTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSLVQVGLLVVVGFWQMQNLKSFFRAKKLV 215
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Planmine SMEST
Match: SMESG000058563.1 (SMESG000058563.1)

HSP 1 Score: 134.806 bits (338), Expect = 8.673e-39
Identity = 68/175 (38.86%), Postives = 110/175 (62.86%), Query Frame = 3 
Query:  192 MIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            M +G YK E +D ++  YV   +  G+HV + D +  +++S+ Y+ EG F  TTH  GEF +C+ + S  W    KLR++L+ +T E A DY +   +  L   + +++ +I  +  I  +QNYQR +E +FR+T   TNSR+L++S +Q  +L+ VGFWQ+ NLK+FF +KK+V
Sbjct:    1 MNLGYYKIEYYDANQKAYVKKSTHDGLHVIVYDGDGDIIISKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKIV 175
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Planmine SMEST
Match: SMESG000058563.1 (SMESG000058563.1)

HSP 1 Score: 134.806 bits (338), Expect = 9.522e-39
Identity = 68/175 (38.86%), Postives = 110/175 (62.86%), Query Frame = 3 
Query:  192 MIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            M +G YK E +D ++  YV   +  G+HV + D +  +++S+ Y+ EG F  TTH  GEF +C+ + S  W    KLR++L+ +T E A DY +   +  L   + +++ +I  +  I  +QNYQR +E +FR+T   TNSR+L++S +Q  +L+ VGFWQ+ NLK+FF +KK+V
Sbjct:    2 MNLGYYKIEYYDANQKAYVKKSTHDGLHVIVYDGDGDIIISKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKIV 176
[Close]
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Planmine SMEST
Match: SMESG000024933.1 (SMESG000024933.1)

HSP 1 Score: 111.309 bits (277), Expect = 2.193e-29
Identity = 66/216 (30.56%), Postives = 117/216 (54.17%), Query Frame = 3 
Query:   72 MTFTFISIFLSVFILNTNAIYFHIRETESK-CFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSXXXXXXXXXXXFWQMQNLKSFFRAKKLV 716
            M F  IS+F+  F+  T+AI F +     K C  EE+ ++ ++ G+Y            +    G    +++TD +  V+  +   S+G+F  TT     F +C+ +       G    V L+I+ G   ++Y  +A  +KL  L++ +++L D  ++I K+  Y RDRE + RDT+EST++RV YFS+  +G L+ +  WQ+  L+ +F++KKL+
Sbjct:    1 MNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 205
The following BLAST results are available for this feature:
BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TMED41.743e-9063.37transmembrane p24 trafficking protein 4 [Source:HG... [more]
TMED91.976e-8963.03transmembrane p24 trafficking protein 9 [Source:HG... [more]
TMED42.174e-7163.40transmembrane p24 trafficking protein 4 [Source:HG... [more]
TMED41.576e-5044.06transmembrane p24 trafficking protein 4 [Source:HG... [more]
TMED103.856e-3036.04transmembrane p24 trafficking protein 10 [Source:H... [more]
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BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Y60A3A.96.047e-8657.55pep chromosome:WBcel235:V:19946691:19949093:-1 gen... [more]
T08D2.17.408e-4748.55pep chromosome:WBcel235:X:162529:163134:-1 gene:WB... [more]
F47G9.13.240e-2630.19pep chromosome:WBcel235:V:11323965:11326964:-1 gen... [more]
sel-97.142e-1024.17Suppressor/enhancer of lin-12 protein 9 [Source:U... [more]
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BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
eca2.775e-9061.79gene:FBgn0069242 transcript:FBtr0082098[more]
p24-21.875e-8159.41gene:FBgn0053105 transcript:FBtr0082093[more]
p24-21.875e-8159.41gene:FBgn0053105 transcript:FBtr0303038[more]
bai7.410e-1825.47gene:FBgn0045866 transcript:FBtr0084758[more]
CHOp246.934e-826.14gene:FBgn0029709 transcript:FBtr0343566[more]
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BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed41.770e-9460.27transmembrane p24 trafficking protein 4 [Source:ZF... [more]
tmed97.544e-9362.39transmembrane p24 trafficking protein 9 [Source:ZF... [more]
si:ch211-255i20.31.884e-5339.73si:ch211-255i20.3 [Source:ZFIN;Acc:ZDB-GENE-141216... [more]
tmed101.120e-2631.82transmembrane p24 trafficking protein 10 [Source:Z... [more]
tmed101.120e-2631.82transmembrane p24 trafficking protein 10 [Source:Z... [more]
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BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed47.118e-8960.27transmembrane p24 trafficking protein 4 [Source:NC... [more]
tmed95.441e-8759.91transmembrane p24 trafficking protein 9 [Source:NC... [more]
thnsl17.602e-5341.43threonine synthase like 1 [Source:Xenbase;Acc:XB-G... [more]
shroom12.122e-2832.84shroom family member 1 [Source:Xenbase;Acc:XB-GENE... [more]
enpp71.352e-2531.43ectonucleotide pyrophosphatase/phosphodiesterase 7... [more]
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BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tmed42.487e-9161.50transmembrane p24 trafficking protein 4 [Source:MG... [more]
Tmed92.638e-8964.50transmembrane p24 trafficking protein 9 [Source:MG... [more]
Tmed99.535e-7364.37transmembrane p24 trafficking protein 9 [Source:MG... [more]
Tmed41.441e-6559.15transmembrane p24 trafficking protein 4 [Source:MG... [more]
Tmed115.001e-6046.33transmembrane p24 trafficking protein 11 [Source:M... [more]
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BLAST of transmembrane emp24 domain-containing protein eca-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8R1V4|TMED4_MOUSE1.740e-9061.50Transmembrane emp24 domain-containing protein 4 OS... [more]
sp|B3NZM5|TMEDE_DROER2.577e-9062.26Transmembrane emp24 domain-containing protein eca ... [more]
sp|B4PVC6|TMEDE_DROYA4.447e-9061.79Transmembrane emp24 domain-containing protein eca ... [more]
sp|Q7Z7H5|TMED4_HUMAN8.371e-9063.37Transmembrane emp24 domain-containing protein 4 OS... [more]
sp|Q9I7K5|TMEDE_DROME2.781e-8961.79Transmembrane emp24 domain-containing protein eca ... [more]
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BLAST of transmembrane emp24 domain-containing protein eca-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267ES546.367e-10168.54GOLD domain-containing protein OS=Macrostomum lign... [more]
A0A267F1051.149e-10068.54GOLD domain-containing protein OS=Macrostomum lign... [more]
A0A1I8HRM92.247e-9971.14GOLD domain-containing protein OS=Macrostomum lign... [more]
A0A1S3K6271.247e-9769.54transmembrane emp24 domain-containing protein eca-... [more]
A0A1S3HQP81.317e-9769.54transmembrane emp24 domain-containing protein eca ... [more]
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BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed47.390e-9261.90transmembrane p24 trafficking protein 4 [Source:ZF... [more]
tmed93.077e-9161.93transmembrane p24 trafficking protein 9 [Source:NC... [more]
tmed95.013e-9161.93transmembrane p24 trafficking protein 9 [Source:NC... [more]
si:ch211-255i20.31.989e-4839.17transmembrane emp24 domain-containing protein 11-l... [more]
tmed106.518e-2732.21transmembrane p24 trafficking protein 10 [Source:N... [more]
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BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000001929.13.523e-7865.71pep scaffold:Pmarinus_7.0:GL476868:73855:89088:-1 ... [more]
tmed22.269e-826.17transmembrane p24 trafficking protein 2 [Source:ZF... [more]
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BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4
Match NameE-valueIdentityDescription
ERP66.458e-3033.64Member of the p24 family involved in ER to Golgi t... [more]
ERP14.044e-2528.57Member of the p24 family involved in ER to Golgi t... [more]
ERV252.322e-1831.34Member of the p24 family involved in ER to Golgi t... [more]
ERP59.297e-1730.69Protein with similarity to Emp24p and Erv25p; memb... [more]
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BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO359534.227e-9360.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO412392.151e-2729.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO412404.198e-1125.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO315476.433e-1124.88Transmembrane emp24 domain-containing protein [So... [more]
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BLAST of transmembrane emp24 domain-containing protein eca-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed41.110e-9262.56transmembrane emp24 domain-containing protein 4 [S... [more]
tmed41.784e-9262.09transmembrane emp24 domain-containing protein 4 [S... [more]
tmed95.540e-8964.39transmembrane emp24 domain-containing protein 9 [S... [more]
si:ch211-255i20.36.124e-4440.00transmembrane emp24 domain-containing protein 11-l... [more]
tmed109.653e-2833.84transmembrane p24 trafficking protein 10 [Source:N... [more]
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BLAST of transmembrane emp24 domain-containing protein eca-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000073800.12.208e-154100.00SMESG000073800.1[more]
SMESG000073800.12.856e-150100.00SMESG000073800.1[more]
SMESG000058563.18.673e-3938.86SMESG000058563.1[more]
SMESG000058563.19.522e-3938.86SMESG000058563.1[more]
SMESG000024933.12.193e-2930.56SMESG000024933.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002714 ID=SMED30002714|Name=transmembrane emp24 domain-containing protein eca-like|organism=Schmidtea mediterranea sexual|type=transcript|length=894bp
CGTCGATACTTACTGTTTGAATAGTTTAAAACAATTTTTAAGTGCCACTT
TTTAAAATCATGAATAATTGTATGACGTTTACATTTATTTCAATTTTTTT
ATCAGTATTTATTTTGAATACCAATGCCATTTATTTTCATATAAGAGAAA
CTGAATCTAAATGTTTCATCGAAGAAGTTCCTGAGGATACGATGATCGTT
GGTAAATACAAGACTGAAATCTTTGATAAAAGCAAAAATGTTTATGTTCC
AACTGTGTCAGGATTGGGTATGCACGTTGAAATTACTGACCCTGAAAAGA
AGGTGGTTCTGTCAAGAACGTATTCTTCTGAGGGTAGATTTGTTCATACT
ACTCATTCATCTGGTGAATTTGCAATTTGTCTTCATTCTAATTCATCTGT
TTGGTTTGGTGGAGCAAAATTACGAGTTCATTTGGAAATTCAAACTGGAG
AGCATGCTCAGGATTATAAAGAAATTGCTGCTAAAGATAAACTGACTGAT
TTACAATTACGTGTAAGACAATTAATTGACCAAGTTGAACAAATAACAAA
GGAACAGAATTATCAAAGAGATAGAGAAGCTAGATTTAGAGACACAAGTG
AGAGTACGAACTCCAGAGTTCTGTATTTCAGTTTAGTACAAGTCGGTCTC
CTTGTTGTAGTTGGGTTTTGGCAGATGCAAAATTTAAAATCCTTTTTCAG
AGCCAAAAAGCTTGTGTAAAATATTATTGGGAATTTACTCATTCCACACA
GCGTACTAGTTTTGTGAATAATATTATCTGAAAAATAATTTAATTATTGT
TTTATAATTTGTTTGTCGTTGATATCTTTATTACATGAATAATAAATTGT
TCATTATAATTTTTATTAAATCTGAAATAAATTTTATTTTTCGA
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protein sequence of SMED30002714-orf-1

>SMED30002714-orf-1 ID=SMED30002714-orf-1|Name=SMED30002714-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=220bp
MNNCMTFTFISIFLSVFILNTNAIYFHIRETESKCFIEEVPEDTMIVGKY
KTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHS
SGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQL
RVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSLVQVGLLVV
VGFWQMQNLKSFFRAKKLV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005789endoplasmic reticulum membrane
GO:0016021integral component of membrane
GO:0005783endoplasmic reticulum
GO:0016020membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR015720TMP21-related
IPR009038GOLD_dom
Vocabulary: biological process
TermDefinition
GO:0006810transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 145..165
NoneNo IPR availablePANTHERPTHR22811:SF37TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 9coord: 11..219
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..23
score: 0.813
NoneNo IPR availableTMHMMTMhelixcoord: 187..206
NoneNo IPR availableTMHMMTMhelixcoord: 4..26
IPR009038GOLD domainSMARTSM01190EMP24_GP25L_2coord: 23..214
e-value: 1.1E-70
score: 250.8
IPR009038GOLD domainPFAMPF01105EMP24_GP25Lcoord: 23..214
e-value: 2.0E-50
score: 171.2
IPR009038GOLD domainPROSITEPS50866GOLDcoord: 33..129
score: 14.79
IPR015720TMP21-relatedPANTHERPTHR22811TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEINcoord: 11..219