60S ribosomal protein L23a
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002703 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 18
Homology
BLAST of 60S ribosomal protein L23a vs. Ensembl Human
Match: RPL23A (ribosomal protein L23a [Source:HGNC Symbol;Acc:HGNC:10317]) HSP 1 Score: 139.428 bits (350), Expect = 1.277e-41 Identity = 72/125 (57.60%), Postives = 88/125 (70.40%), Query Frame = 3 Query: 156 ILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 +L G H + ++IRT+P F+RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 21 VLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 144
BLAST of 60S ribosomal protein L23a vs. Ensembl Human
Match: RPL23A (ribosomal protein L23a [Source:HGNC Symbol;Acc:HGNC:10317]) HSP 1 Score: 139.813 bits (351), Expect = 1.356e-41 Identity = 72/125 (57.60%), Postives = 88/125 (70.40%), Query Frame = 3 Query: 156 ILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 +L G H + ++IRT+P F+RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 47 VLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 170
BLAST of 60S ribosomal protein L23a vs. Ensembl Human
Match: RPL23A (ribosomal protein L23a [Source:HGNC Symbol;Acc:HGNC:10317]) HSP 1 Score: 138.658 bits (348), Expect = 6.181e-41 Identity = 72/125 (57.60%), Postives = 88/125 (70.40%), Query Frame = 3 Query: 156 ILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 +L G H + ++IRT+P F+RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 66 VLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 189
BLAST of 60S ribosomal protein L23a vs. Ensembl Human
Match: RPL23A (ribosomal protein L23a [Source:HGNC Symbol;Acc:HGNC:10317]) HSP 1 Score: 136.732 bits (343), Expect = 1.082e-40 Identity = 71/122 (58.20%), Postives = 86/122 (70.49%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H + ++IRT+P F+RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 31 GVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 151
BLAST of 60S ribosomal protein L23a vs. Ensembl Human
Match: RPL23A (ribosomal protein L23a [Source:HGNC Symbol;Acc:HGNC:10317]) HSP 1 Score: 136.346 bits (342), Expect = 1.381e-40 Identity = 71/122 (58.20%), Postives = 86/122 (70.49%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H + ++IRT+P F+RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 33 GVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 153
BLAST of 60S ribosomal protein L23a vs. Ensembl Celegans
Match: rpl-25.1 (60S ribosomal protein L23a 1 [Source:UniProtKB/Swiss-Prot;Acc:P48162]) HSP 1 Score: 130.568 bits (327), Expect = 8.774e-39 Identity = 66/128 (51.56%), Postives = 90/128 (70.31%), Query Frame = 3 Query: 147 KSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 K K++ G R++RT+ F+RPVT K R ++ R S+ + +K+D FRI++HPLTTESAMK IEE NTLVF V A K+ IK A+ KLY+++++K+NTL KKA+V+L ADYDALDVAN Sbjct: 16 KKKVVKGKRTTHRRQVRTSVHFRRPVTLKTARQARFPRKSAPKTSKMDHFRIIQHPLTTESAMKKIEEHNTLVFIVSNDANKYQIKDAVHKLYNVQALKVNTL-ITPLQQKKAYVRLTADYDALDVAN 142
BLAST of 60S ribosomal protein L23a vs. Ensembl Celegans
Match: rpl-25.2 (60S ribosomal protein L23a 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20647]) HSP 1 Score: 123.635 bits (309), Expect = 4.466e-36 Identity = 64/130 (49.23%), Postives = 88/130 (67.69%), Query Frame = 3 Query: 141 QVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 Q K ++ G+ + +RT+ F+RP T R P+Y R S+ +KLD F ++K P TTES+MK IE+ NTLVF VD+ A KH+IK A+ LY++K+VK+NTL KKA+V+LA+DYDALDVAN Sbjct: 13 QAKKAVVKGSKTNVRKNVRTSVHFRRPKTLVTARAPRYARKSAPARDKLDSFAVIKAPHTTESSMKKIEDHNTLVFIVDEKANKHHIKRAVHALYNVKAVKVNTL-ITPLQQKKAYVRLASDYDALDVAN 141
BLAST of 60S ribosomal protein L23a vs. Ensembl Celegans
Match: rpl-25.2 (60S ribosomal protein L23a 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20647]) HSP 1 Score: 123.635 bits (309), Expect = 4.466e-36 Identity = 64/130 (49.23%), Postives = 88/130 (67.69%), Query Frame = 3 Query: 141 QVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 Q K ++ G+ + +RT+ F+RP T R P+Y R S+ +KLD F ++K P TTES+MK IE+ NTLVF VD+ A KH+IK A+ LY++K+VK+NTL KKA+V+LA+DYDALDVAN Sbjct: 13 QAKKAVVKGSKTNVRKNVRTSVHFRRPKTLVTARAPRYARKSAPARDKLDSFAVIKAPHTTESSMKKIEDHNTLVFIVDEKANKHHIKRAVHALYNVKAVKVNTL-ITPLQQKKAYVRLASDYDALDVAN 141
BLAST of 60S ribosomal protein L23a vs. Ensembl Celegans
Match: rpl-25.2 (60S ribosomal protein L23a 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20647]) HSP 1 Score: 123.635 bits (309), Expect = 4.466e-36 Identity = 64/130 (49.23%), Postives = 88/130 (67.69%), Query Frame = 3 Query: 141 QVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 Q K ++ G+ + +RT+ F+RP T R P+Y R S+ +KLD F ++K P TTES+MK IE+ NTLVF VD+ A KH+IK A+ LY++K+VK+NTL KKA+V+LA+DYDALDVAN Sbjct: 13 QAKKAVVKGSKTNVRKNVRTSVHFRRPKTLVTARAPRYARKSAPARDKLDSFAVIKAPHTTESSMKKIEDHNTLVFIVDEKANKHHIKRAVHALYNVKAVKVNTL-ITPLQQKKAYVRLASDYDALDVAN 141
BLAST of 60S ribosomal protein L23a vs. Ensembl Celegans
Match: rpl-25.2 (60S ribosomal protein L23a 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20647]) HSP 1 Score: 123.635 bits (309), Expect = 4.466e-36 Identity = 64/130 (49.23%), Postives = 88/130 (67.69%), Query Frame = 3 Query: 141 QVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 Q K ++ G+ + +RT+ F+RP T R P+Y R S+ +KLD F ++K P TTES+MK IE+ NTLVF VD+ A KH+IK A+ LY++K+VK+NTL KKA+V+LA+DYDALDVAN Sbjct: 13 QAKKAVVKGSKTNVRKNVRTSVHFRRPKTLVTARAPRYARKSAPARDKLDSFAVIKAPHTTESSMKKIEDHNTLVFIVDEKANKHHIKRAVHALYNVKAVKVNTL-ITPLQQKKAYVRLASDYDALDVAN 141
BLAST of 60S ribosomal protein L23a vs. Ensembl Fly
Match: RpL23A (gene:FBgn0026372 transcript:FBtr0474640) HSP 1 Score: 129.413 bits (324), Expect = 8.750e-37 Identity = 67/131 (51.15%), Postives = 90/131 (68.70%), Query Frame = 3 Query: 138 EQVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 ++V+ KI+ GA R R+IRT F+RP T K R+PKY R S N++D + I+K+PLTTE+AMK IE+ NTLVF A K++++ A+RKLYDIK K+N L KKA+V+LA DYDALD+AN Sbjct: 143 KKVQKKIIKGAFGTRARKIRTNVHFRRPTTLKLPRSPKYPRKSVPTRNRMDAYNIIKYPLTTEAAMKKIEDNNTLVFLTHLRANKNHVRAAVRKLYDIKVAKVNVL-IRPDGQKKAYVRLARDYDALDIAN 272
BLAST of 60S ribosomal protein L23a vs. Ensembl Fly
Match: RpL23A (gene:FBgn0026372 transcript:FBtr0072805) HSP 1 Score: 129.413 bits (324), Expect = 8.750e-37 Identity = 67/131 (51.15%), Postives = 90/131 (68.70%), Query Frame = 3 Query: 138 EQVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 ++V+ KI+ GA R R+IRT F+RP T K R+PKY R S N++D + I+K+PLTTE+AMK IE+ NTLVF A K++++ A+RKLYDIK K+N L KKA+V+LA DYDALD+AN Sbjct: 143 KKVQKKIIKGAFGTRARKIRTNVHFRRPTTLKLPRSPKYPRKSVPTRNRMDAYNIIKYPLTTEAAMKKIEDNNTLVFLTHLRANKNHVRAAVRKLYDIKVAKVNVL-IRPDGQKKAYVRLARDYDALDIAN 272
BLAST of 60S ribosomal protein L23a vs. Ensembl Zebrafish
Match: rpl23a (ribosomal protein L23a [Source:ZFIN;Acc:ZDB-GENE-030131-7479]) HSP 1 Score: 137.117 bits (344), Expect = 4.360e-41 Identity = 72/122 (59.02%), Postives = 85/122 (69.67%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H + ++IRTTP F RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 27 GVHSQKKKKIRTTPTFHRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKHAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 147
BLAST of 60S ribosomal protein L23a vs. Ensembl Zebrafish
Match: rpl23a (ribosomal protein L23a [Source:ZFIN;Acc:ZDB-GENE-030131-7479]) HSP 1 Score: 136.732 bits (343), Expect = 5.796e-41 Identity = 72/122 (59.02%), Postives = 85/122 (69.67%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H + ++IRTTP F RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 22 GVHSQKKKKIRTTPTFHRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKHAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 142
BLAST of 60S ribosomal protein L23a vs. Ensembl Zebrafish
Match: rpl23a (ribosomal protein L23a [Source:ZFIN;Acc:ZDB-GENE-030131-7479]) HSP 1 Score: 136.732 bits (343), Expect = 5.799e-41 Identity = 72/122 (59.02%), Postives = 85/122 (69.67%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H + ++IRTTP F RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 30 GVHSQKKKKIRTTPTFHRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKHAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 150
BLAST of 60S ribosomal protein L23a vs. Ensembl Xenopus
Match: rpl23a (ribosomal protein L23a [Source:NCBI gene;Acc:448689]) HSP 1 Score: 133.65 bits (335), Expect = 1.657e-39 Identity = 70/122 (57.38%), Postives = 85/122 (69.67%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H + ++IRT+P F+RP T + R PKY R S+ NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 30 GVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPTRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVQKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 150
BLAST of 60S ribosomal protein L23a vs. Ensembl Xenopus
Match: rpl23a (ribosomal protein L23a [Source:NCBI gene;Acc:448689]) HSP 1 Score: 132.109 bits (331), Expect = 1.685e-38 Identity = 70/122 (57.38%), Postives = 85/122 (69.67%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H + ++IRT+P F+RP T + R PKY R S+ NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 64 GVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPTRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVQKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 184
BLAST of 60S ribosomal protein L23a vs. Ensembl Mouse
Match: Rpl23a (ribosomal protein L23A [Source:MGI Symbol;Acc:MGI:3040672]) HSP 1 Score: 136.732 bits (343), Expect = 7.426e-41 Identity = 71/122 (58.20%), Postives = 86/122 (70.49%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H + ++IRT+P F+RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 31 GVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 151
BLAST of 60S ribosomal protein L23a vs. UniProt/SwissProt
Match: sp|P62752|RL23A_RAT (60S ribosomal protein L23a OS=Rattus norvegicus OX=10116 GN=Rpl23a PE=2 SV=1) HSP 1 Score: 136.732 bits (343), Expect = 5.195e-40 Identity = 71/122 (58.20%), Postives = 86/122 (70.49%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H + ++IRT+P F+RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 31 GVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 151
BLAST of 60S ribosomal protein L23a vs. UniProt/SwissProt
Match: sp|P62751|RL23A_MOUSE (60S ribosomal protein L23a OS=Mus musculus OX=10090 GN=Rpl23a PE=1 SV=1) HSP 1 Score: 136.732 bits (343), Expect = 5.195e-40 Identity = 71/122 (58.20%), Postives = 86/122 (70.49%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H + ++IRT+P F+RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 31 GVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 151
BLAST of 60S ribosomal protein L23a vs. UniProt/SwissProt
Match: sp|P62750|RL23A_HUMAN (60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1) HSP 1 Score: 136.732 bits (343), Expect = 5.195e-40 Identity = 71/122 (58.20%), Postives = 86/122 (70.49%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H + ++IRT+P F+RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 31 GVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 151
BLAST of 60S ribosomal protein L23a vs. UniProt/SwissProt
Match: sp|Q24JY1|RL23A_BOVIN (60S ribosomal protein L23a OS=Bos taurus OX=9913 GN=RPL23A PE=2 SV=1) HSP 1 Score: 136.732 bits (343), Expect = 5.195e-40 Identity = 71/122 (58.20%), Postives = 86/122 (70.49%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H + ++IRT+P F+RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 31 GVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 151
BLAST of 60S ribosomal protein L23a vs. UniProt/SwissProt
Match: sp|P48162|R23A1_CAEEL (60S ribosomal protein L23a 1 OS=Caenorhabditis elegans OX=6239 GN=rpl-25.1 PE=3 SV=1) HSP 1 Score: 130.568 bits (327), Expect = 1.116e-37 Identity = 66/128 (51.56%), Postives = 90/128 (70.31%), Query Frame = 3 Query: 147 KSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 K K++ G R++RT+ F+RPVT K R ++ R S+ + +K+D FRI++HPLTTESAMK IEE NTLVF V A K+ IK A+ KLY+++++K+NTL KKA+V+L ADYDALDVAN Sbjct: 16 KKKVVKGKRTTHRRQVRTSVHFRRPVTLKTARQARFPRKSAPKTSKMDHFRIIQHPLTTESAMKKIEEHNTLVFIVSNDANKYQIKDAVHKLYNVQALKVNTL-ITPLQQKKAYVRLTADYDALDVAN 142
BLAST of 60S ribosomal protein L23a vs. TrEMBL
Match: A0A0U2LEL3 (60S ribosomal protein L23a OS=Acartia pacifica OX=335913 PE=2 SV=1) HSP 1 Score: 148.288 bits (373), Expect = 8.213e-42 Identity = 73/130 (56.15%), Postives = 94/130 (72.31%), Query Frame = 3 Query: 141 QVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 + K K++ G H RV+++RT+ KF RP T+KP RNPKY R S+ + NK+D + I+KHPLTTESAMK IE+ NTLVF D A KH ++ A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 40 KTKKKVVKGLHGTRVKKVRTSVKFYRPKTFKPPRNPKYPRKSTPKRNKMDAYAIIKHPLTTESAMKKIEDNNTLVFICDIKANKHQVRAAVKKLYDINVAKVNTL-VRPDGQKKAYVRLAPDYDALDVAN 168
BLAST of 60S ribosomal protein L23a vs. TrEMBL
Match: A0A0U2M8Z7 (60S ribosomal protein L23a OS=Acartia pacifica OX=335913 PE=2 SV=1) HSP 1 Score: 147.132 bits (370), Expect = 2.161e-41 Identity = 72/130 (55.38%), Postives = 94/130 (72.31%), Query Frame = 3 Query: 141 QVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 + K K++ G H RV+++RT+ KF RP T+KP RNPKY R S+ + NK+D + I++HPLTTESAMK IE+ NTLVF D A KH ++ A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 40 KTKKKVVKGLHGTRVKKVRTSVKFYRPKTFKPPRNPKYPRKSTPKRNKMDAYAIIRHPLTTESAMKKIEDNNTLVFICDIKANKHQVRAAVKKLYDINVAKVNTL-VRPDGQKKAYVRLAPDYDALDVAN 168
BLAST of 60S ribosomal protein L23a vs. TrEMBL
Match: A0A267G2U2 (Ribosomal_L23eN domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022537g1 PE=3 SV=1) HSP 1 Score: 145.976 bits (367), Expect = 2.339e-41 Identity = 75/130 (57.69%), Postives = 97/130 (74.62%), Query Frame = 3 Query: 141 QVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 + K + L G R R+IRTTP+FKRP TY+P R PKY R S R N LD F+I+++PLTTES+MK IEE+NTLVF VD+ A+K IK A++KLYDI++ K+NTL KKA+VKL+A++DALDVAN Sbjct: 5 KAKGQQLKGTQQLRKRKIRTTPRFKRPETYRPPRAPKYARRSLPRRNALDAFKIMQYPLTTESSMKKIEEQNTLVFIVDKRASKPLIKDAVKKLYDIQASKVNTL-IRPDGLKKAYVKLSAEHDALDVAN 133
BLAST of 60S ribosomal protein L23a vs. TrEMBL
Match: A0A267F1T4 (Ribosomal_L23eN domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022537g2 PE=3 SV=1) HSP 1 Score: 145.591 bits (366), Expect = 2.653e-41 Identity = 75/130 (57.69%), Postives = 97/130 (74.62%), Query Frame = 3 Query: 141 QVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 + K + L G R R+IRTTP+FKRP TY+P R PKY R S R N LD F+I+++PLTTES+MK IEE+NTLVF VD+ A+K IK A++KLYDI++ K+NTL KKA+VKL+A++DALDVAN Sbjct: 2 KAKGQQLKGTQQLRKRKIRTTPRFKRPETYRPPRAPKYARRSLPRRNALDAFKIMQYPLTTESSMKKIEEQNTLVFIVDKRASKPLIKDAVKKLYDIQASKVNTL-IRPDGLKKAYVKLSAEHDALDVAN 130
BLAST of 60S ribosomal protein L23a vs. TrEMBL
Match: A0A0U2V8U3 (60S ribosomal protein L23a OS=Pseudodiaptomus poplesia OX=213370 PE=2 SV=1) HSP 1 Score: 144.821 bits (364), Expect = 1.817e-40 Identity = 71/130 (54.62%), Postives = 92/130 (70.77%), Query Frame = 3 Query: 141 QVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 + + +++ G H RV+++RT+ KF RP T++P R PKY R S+ R N++D + I+KHPLTTESAMK IE+ NTLVF D A KH IK A+ KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 48 KTQKRVVKGVHGTRVKKVRTSVKFYRPKTFRPQRTPKYPRKSTPRRNRMDAYSIIKHPLTTESAMKKIEDNNTLVFITDIKANKHQIKAAVGKLYDISVSKVNTL-IRPDGQKKAYVRLAPDYDALDVAN 176
BLAST of 60S ribosomal protein L23a vs. Ensembl Cavefish
Match: rpl23a (ribosomal protein L23a [Source:NCBI gene;Acc:103044345]) HSP 1 Score: 137.887 bits (346), Expect = 1.713e-41 Identity = 72/122 (59.02%), Postives = 86/122 (70.49%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H R +++RT+P F+RP T + R PKY R S+ R NKLD + IVK PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 30 GVHSQRKKKMRTSPTFRRPKTMRLRRQPKYPRKSAPRRNKLDHYAIVKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKHAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 150
BLAST of 60S ribosomal protein L23a vs. Ensembl Sea Lamprey
Match: rpl23a (ribosomal protein L23a [Source:ZFIN;Acc:ZDB-GENE-030131-7479]) HSP 1 Score: 130.954 bits (328), Expect = 1.851e-39 Identity = 66/125 (52.80%), Postives = 86/125 (68.80%), Query Frame = 3 Query: 156 ILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 +L G H R R++ T+P F+RP T + R PKY R S+ NK+D + I+K PLTTE+AMK IE+ NTLVF D A KH IKLA++KLY+I +K+NTL KKA+V+L D+DALDVAN Sbjct: 27 VLRGVHAVRRRKVHTSPTFRRPHTLRLRRQPKYPRKSAPTRNKMDHYAIIKFPLTTEAAMKKIEDNNTLVFITDVRANKHQIKLAVKKLYNIGVMKVNTL-IRPDGEKKAYVRLTPDFDALDVAN 150
BLAST of 60S ribosomal protein L23a vs. Ensembl Yeast
Match: RPL25 (Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23 [Source:SGD;Acc:S000005487]) HSP 1 Score: 108.612 bits (270), Expect = 4.771e-31 Identity = 52/122 (42.62%), Postives = 82/122 (67.21%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G + + ++RT+ F+ P T K R PKY + N+LD +++++ P+T+E+AMK +E+ N LVF V A K+ IK A+++LY++ +K+NTL + TKKA+V+L ADYDALD+AN Sbjct: 17 GTNGKKALKVRTSATFRLPKTLKLARAPKYASKAVPHYNRLDSYKVIEQPITSETAMKKVEDGNILVFQVSMKANKYQIKKAVKELYEVDVLKVNTL-VRPNGTKKAYVRLTADYDALDIAN 137
BLAST of 60S ribosomal protein L23a vs. Ensembl Nematostella
Match: EDO47563 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RM97]) HSP 1 Score: 134.035 bits (336), Expect = 2.119e-40 Identity = 70/131 (53.44%), Postives = 89/131 (67.94%), Query Frame = 3 Query: 138 EQVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 ++ K + G + +++RT+ KF RP T RNPKY R+S+ R NKLD + I+KHPLTTESAMK IE+ NTLVF VD A K IK A++KLYDI K+NTL KKA+V+LA DYDALDV+N Sbjct: 20 QKAKKAVQKGVRAAKTKKVRTSVKFHRPKTLSLRRNPKYPRTSAPRINKLDHYAIIKHPLTTESAMKKIEDNNTLVFIVDVRANKPQIKAAVKKLYDIVVSKVNTL-VRPDGQKKAYVRLAPDYDALDVSN 149
BLAST of 60S ribosomal protein L23a vs. Ensembl Medaka
Match: rpl23a (ribosomal protein L23a [Source:NCBI gene;Acc:101172837]) HSP 1 Score: 136.346 bits (342), Expect = 1.163e-40 Identity = 71/122 (58.20%), Postives = 86/122 (70.49%), Query Frame = 3 Query: 165 GAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 G H + ++IRT+P F+RP T + R PKY R S+ R NKLD + I+K PLTTESAMK IE+ NTLVF VD A KH IK A++KLYDI K+NTL KKA+V+LA DYDALDVAN Sbjct: 45 GVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKHAVKKLYDIDVAKVNTL-IRPDGEKKAYVRLAPDYDALDVAN 165
BLAST of 60S ribosomal protein L23a vs. Planmine SMEST
Match: SMESG000074545.1 (SMESG000074545.1) HSP 1 Score: 291.967 bits (746), Expect = 3.567e-102 Identity = 167/167 (100.00%), Postives = 167/167 (100.00%), Query Frame = 3 Query: 30 MAAKSHKEVVRNRRHVXXXXXXXXXXXXXXXXXXXXEQVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 530 MAAKSHKEVVRNRRHVKMALKKKEAKAKSATKAKVAEQVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN Sbjct: 1 MAAKSHKEVVRNRRHVKMALKKKEAKAKSATKAKVAEQVKSKILNGAHVGRVRRIRTTPKFKRPVTYKPLRNPKYQRSSSTRENKLDEFRIVKHPLTTESAMKMIEEKNTLVFSVDQHATKHNIKLAIRKLYDIKSVKINTLNCISSNTKKAFVKLAADYDALDVAN 167 The following BLAST results are available for this feature:
BLAST of 60S ribosomal protein L23a vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of 60S ribosomal protein L23a vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of 60S ribosomal protein L23a vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 2
BLAST of 60S ribosomal protein L23a vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of 60S ribosomal protein L23a vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 2
BLAST of 60S ribosomal protein L23a vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 1
BLAST of 60S ribosomal protein L23a vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of 60S ribosomal protein L23a vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of 60S ribosomal protein L23a vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of 60S ribosomal protein L23a vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of 60S ribosomal protein L23a vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of 60S ribosomal protein L23a vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of 60S ribosomal protein L23a vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of 60S ribosomal protein L23a vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002703 ID=SMED30002703|Name=60S ribosomal protein L23a|organism=Schmidtea mediterranea sexual|type=transcript|length=581bpback to top protein sequence of SMED30002703-orf-1 >SMED30002703-orf-1 ID=SMED30002703-orf-1|Name=SMED30002703-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=173bp MAAKSHKEVVRNRRHVKMALKKKEAKAKSATKAKVAEQVKSKILNGAHVGback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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