CREB-binding protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002665 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of CREB-binding protein vs. Ensembl Human
Match: EP300 (E1A binding protein p300 [Source:HGNC Symbol;Acc:HGNC:3373]) HSP 1 Score: 757.673 bits (1955), Expect = 0.000e+0 Identity = 387/817 (47.37%), Postives = 516/817 (63.16%), Query Frame = 3
Query: 1041 ATQLSTDVKMSPDSTSTPNKDHTNA-----HKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
+T+L T++K D ST + A K + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS L+++FE +ID +M S G+CCGR+ + PQ L C +C I RDA YY++QN RY CEKC+N+ + + + + + K SK +N+ + E FV C C RK H++C H + IW GF C C+++ + K N + +K LP L ++ENRVN +L+ ++ P EV VRV+ +SDK VEVKPGMK+ + ++ EM ESF YR KA+FAF+EIDG ++CFFG+HVQEYGSDCP PN RRVY++YLDSVHFF P+ RT VYHE L+GYLEY KKLG+T HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA+ E +V DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + ++++ ++K + KK K+ K +SL+ K+ G + ND+S+K+ MEK KE FFVIRL + A +LPPI DPD L DLMDGRD L LAR+KHLEFSSLRRA++ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+ H H + K + D+ESN N Q + + D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 990 STELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQN---------------RYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREEN--------TSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESN--NQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1781 HSP 2 Score: 82.4185 bits (202), Expect = 9.289e-15 Identity = 44/89 (49.44%), Postives = 57/89 (64.04%), Query Frame = 3
Query: 111 VDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQSGK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 330 ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 418
BLAST of CREB-binding protein vs. Ensembl Human
Match: EP300 (E1A binding protein p300 [Source:HGNC Symbol;Acc:HGNC:3373]) HSP 1 Score: 757.288 bits (1954), Expect = 0.000e+0 Identity = 387/817 (47.37%), Postives = 516/817 (63.16%), Query Frame = 3
Query: 1041 ATQLSTDVKMSPDSTSTPNKDHTNA-----HKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
+T+L T++K D ST + A K + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS L+++FE +ID +M S G+CCGR+ + PQ L C +C I RDA YY++QN RY CEKC+N+ + + + + + K SK +N+ + E FV C C RK H++C H + IW GF C C+++ + K N + +K LP L ++ENRVN +L+ ++ P EV VRV+ +SDK VEVKPGMK+ + ++ EM ESF YR KA+FAF+EIDG ++CFFG+HVQEYGSDCP PN RRVY++YLDSVHFF P+ RT VYHE L+GYLEY KKLG+T HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA+ E +V DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + ++++ ++K + KK K+ K +SL+ K+ G + ND+S+K+ MEK KE FFVIRL + A +LPPI DPD L DLMDGRD L LAR+KHLEFSSLRRA++ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+ H H + K + D+ESN N Q + + D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 1016 STELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQN---------------RYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREEN--------TSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESN--NQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1807 HSP 2 Score: 82.4185 bits (202), Expect = 8.272e-15 Identity = 44/89 (49.44%), Postives = 57/89 (64.04%), Query Frame = 3
Query: 111 VDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQSGK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 330 ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 418
BLAST of CREB-binding protein vs. Ensembl Human
Match: CREBBP (CREB binding protein [Source:HGNC Symbol;Acc:HGNC:2348]) HSP 1 Score: 754.592 bits (1947), Expect = 0.000e+0 Identity = 398/832 (47.84%), Postives = 524/832 (62.98%), Query Frame = 3
Query: 1119 KKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK----VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHPET--PCPTSVP 3587
K + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR++ + PQ L C +C I RDA YY++QN RY CEKC+ + + + + + + K K +N+ + E FV C+ C RK H++C H D IW GF C C+++ K N + +K L L ++E+RVNK+L+ ++ P EV VRV++SSDK VEVKPGMKS + ++ EM ESF YR KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN+RRVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R K S T S+ E SQ + + + K + R N +K+ + + ND+S+K+ MEK KE FFVI LH+ LPPI DPD L DLMDGRD L LAR+KH EFSSLRR+K+STLC ELH + ++ +Y CN C +E R+ C CED++LC +CY T++H H + K +D DE S+ Q+ S +++ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQ++RRR+A M P+ P PTS P
Sbjct: 1045 KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQN---------------RYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEES-TAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRAN-----KKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLD-DEGSSQGEPQSKS---PQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAP 1851
BLAST of CREB-binding protein vs. Ensembl Human
Match: CREBBP (CREB binding protein [Source:HGNC Symbol;Acc:HGNC:2348]) HSP 1 Score: 753.821 bits (1945), Expect = 0.000e+0 Identity = 398/832 (47.84%), Postives = 524/832 (62.98%), Query Frame = 3
Query: 1119 KKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK----VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHPET--PCPTSVP 3587
K + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR++ + PQ L C +C I RDA YY++QN RY CEKC+ + + + + + + K K +N+ + E FV C+ C RK H++C H D IW GF C C+++ K N + +K L L ++E+RVNK+L+ ++ P EV VRV++SSDK VEVKPGMKS + ++ EM ESF YR KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN+RRVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R K S T S+ E SQ + + + K + R N +K+ + + ND+S+K+ MEK KE FFVI LH+ LPPI DPD L DLMDGRD L LAR+KH EFSSLRR+K+STLC ELH + ++ +Y CN C +E R+ C CED++LC +CY T++H H + K +D DE S+ Q+ S +++ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQ++RRR+A M P+ P PTS P
Sbjct: 1083 KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQN---------------RYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEES-TAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRAN-----KKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLD-DEGSSQGEPQSKS---PQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAP 1889 HSP 2 Score: 82.4185 bits (202), Expect = 8.219e-15 Identity = 44/91 (48.35%), Postives = 57/91 (62.64%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 344 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLK 434
BLAST of CREB-binding protein vs. Ensembl Human
Match: CREBBP (CREB binding protein [Source:HGNC Symbol;Acc:HGNC:2348]) HSP 1 Score: 565.844 bits (1457), Expect = 3.060e-177 Identity = 263/492 (53.46%), Postives = 333/492 (67.68%), Query Frame = 3
Query: 1119 KKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEE 2588
K + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR++ + PQ L C +C I RDA YY++QN L DRY CEKC+ + + + + + + K K +N+ + E FV C+ C RK H++C H D IW GF C C+++ K N + +K L L ++E+RVNK+L+ ++ P EV VRV++SSDK VEVKPGMKS + ++ EM ESF YR KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN+RRVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E
Sbjct: 618 KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNSSPK-----YGLLADRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQE 1104
BLAST of CREB-binding protein vs. Ensembl Celegans
Match: cbp-1 (pep chromosome:WBcel235:III:9766516:9774807:1 gene:WBGene00000366.1 transcript:R10E11.1c.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cbp-1) HSP 1 Score: 711.835 bits (1836), Expect = 0.000e+0 Identity = 444/1253 (35.43%), Postives = 638/1253 (50.92%), Query Frame = 3
Query: 114 DSDKRFLIRQQLYYLFHASKCTRLAYTTGKGDCHNQ----------HCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR-----PNNNIRKSVSNKPKINGITNYN------DQFNND--KEVNWRNTIL---------------------------SIRPNFLVKLTDELIPVKVCEDVKNHSGYIDVSNYVKSFEFEIFQKAININ------------------------DYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGN------MKDNLEFGTIKKELVANEIP-------------------MTPDKEYEQKLAYGSYIKTESWTENDIDSKRELLESSP------NAAAKSTPVKL-------------PATQLSTDVKMSPDSTSTPNKDHTNAHKK----------WSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDR---DPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEI-DEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHS-QSDAANLP-PINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCSIP-KSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLR 3467
D +KR LI+QQL L HA KC++ NQ HC M+ V+ H+T C G+ C F HC SS++II HWKNC+ +C VC PL+ P ++N +NG +N + QF + + N N++ ++ P + T E +V +D++NH V VK+ E Q+A+N N +Y + LAEK + + L K+N + N+ AH+ P + Q++ E + + +G+ + N +G + +IP TP+ ++ KTE + + DS L S P ++ STP + + Q VK + D + A ++ +S E+L + + + + +D+ PF++PV+ +LL+IPDY I+K PMDL T+ KL G Y N DD WLM +NAWLYN+K SKVYK L+++F S++D +M S G+CC ++ + P L C +C I R+ Y+ F+ + ++E RY C+KC++ + ++ N K+ ++ +N+V + E F C+ C RKWH++CA H ++ +GF C C K + N Y + LPH +LS ++E+RVN ++K + + VI+R L DK EVK MK Y E+ + PE F YR KAVFAF+ IDG EVCFFGLHVQEYGS CP PN+RRVY+AYLDSVHFF PR+ RTDVYHE L+GYL+YAK LG+TMAHIWACPP EGDDYIFH HPPEQK+PKPKRLQ+WY KML+K ++E V++++DI+ A + ++ +PT+LPYFEGD+WPN +ED +E +EE R++K + + KK K K + K+ GS T N+V+ K+ EK KE FF IRL S Q++ A L PI+DPD L SD+MDGRD L ARE+H EFSSLRRAK+STLC Y LH + Y CN C+ + C+ C+DF+LC C T HPH + K+ +++ + T + R SL HACQCRD NCR C KMK +++H + C TC +C+ + +C HAK C+ C VP C+ +R
Sbjct: 399 DPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTSCNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCKPLKRIQDTPLQFSLPDLANLIGVNGNSNGSAEGDGLHQFGSPAMRTGNITNSLFEGFNGNPFQNGPNRGGPRPPGGNGEIPNLPPPDMPDCTKEWH-HQVTKDLRNHL----VGKLVKAIFPEPNQEAMNDNRLKDLIAYARKVEKEMFESANDREEYYHLLAEKIYKIQKELQEKKNSRLNQGAAAHDQYAIPPS--NELAQMLGVEGGRSDVHSEGSSMAVAPSQQNQPWGGAPNSNMHQQIPPNGQVPQVNNSSTFPSSGNSTPNIGASSTVSAMLQPKTEPMDDQNTDS----LSSRPPTAIGFGGSSSSTPAPIMNGIVKKEEDPEESSNQAPPSVKDTKDGVAESKPKEQQAKREPTPPPTEDTVFSQEDLIKFLLPVWEKLDKSEDAAPFRVPVDAKLLNIPDYHEIIKRPMDLETVHKKLYAGQYQNAGQFCDDIWLMLDNAWLYNRKNSKVYKYGLKLSEMFVSEMDPVMKSMGYCCAKKLAFTPLSLFCYGAAMCTIAREQQYWVFEQSSTQYNVTVTE----RYTYCQKCFDALPPEGISLSENPNDRNNMAPKTSFTEQKNSVIDYEPFERCKYCMRKWHRICALHDKKVYPEGFICECCRTAKKYQKPDNKYLASKLPHNKLSTFLEDRVNGFIKKQLQAEAHKYPVIIRTLCVQDKEAEVKAQMKQKYVESNQFPEKFPYRTKAVFAFEIIDGVEVCFFGLHVQEYGSACPAPNARRVYIAYLDSVHFFQPRELRTDVYHELLLGYLDYAKMLGYTMAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQDWYKKMLEKGVQEGSVVEFKDIYKQARDDNLTTPTQLPYFEGDFWPNVIEDCIREASNEEAQRKVKEDD--------DDGEDADGGLGGGDSGKKKSSKNKKNNLKKNAKMNKKKAGSITGNEVADKLYSQFEKHKEVFFTIRLVSLQNEPAVLAKPISDPDGLMQSDMMDGRDTFLTKAREEHWEFSSLRRAKYSTLCLAYSLHETDSKGMEYTCNKCSS--PAVWHCQSCDDFDLCDGCKPTTQHPHEMEKI-----KSLIGGGEAGDSAAGGTRYESIQRCIASLVHACQCRDANCRRMSCHKMKRVVQHTKMCKKRINGTCPVCKQLIALCCYHAKHCTRDACTVPFCMNIR 1621
BLAST of CREB-binding protein vs. Ensembl Celegans
Match: cbp-1 (pep chromosome:WBcel235:III:9766516:9774825:1 gene:WBGene00000366.1 transcript:R10E11.1c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cbp-1) HSP 1 Score: 711.835 bits (1836), Expect = 0.000e+0 Identity = 444/1253 (35.43%), Postives = 638/1253 (50.92%), Query Frame = 3
Query: 114 DSDKRFLIRQQLYYLFHASKCTRLAYTTGKGDCHNQ----------HCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR-----PNNNIRKSVSNKPKINGITNYN------DQFNND--KEVNWRNTIL---------------------------SIRPNFLVKLTDELIPVKVCEDVKNHSGYIDVSNYVKSFEFEIFQKAININ------------------------DYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGN------MKDNLEFGTIKKELVANEIP-------------------MTPDKEYEQKLAYGSYIKTESWTENDIDSKRELLESSP------NAAAKSTPVKL-------------PATQLSTDVKMSPDSTSTPNKDHTNAHKK----------WSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDR---DPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEI-DEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHS-QSDAANLP-PINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCSIP-KSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLR 3467
D +KR LI+QQL L HA KC++ NQ HC M+ V+ H+T C G+ C F HC SS++II HWKNC+ +C VC PL+ P ++N +NG +N + QF + + N N++ ++ P + T E +V +D++NH V VK+ E Q+A+N N +Y + LAEK + + L K+N + N+ AH+ P + Q++ E + + +G+ + N +G + +IP TP+ ++ KTE + + DS L S P ++ STP + + Q VK + D + A ++ +S E+L + + + + +D+ PF++PV+ +LL+IPDY I+K PMDL T+ KL G Y N DD WLM +NAWLYN+K SKVYK L+++F S++D +M S G+CC ++ + P L C +C I R+ Y+ F+ + ++E RY C+KC++ + ++ N K+ ++ +N+V + E F C+ C RKWH++CA H ++ +GF C C K + N Y + LPH +LS ++E+RVN ++K + + VI+R L DK EVK MK Y E+ + PE F YR KAVFAF+ IDG EVCFFGLHVQEYGS CP PN+RRVY+AYLDSVHFF PR+ RTDVYHE L+GYL+YAK LG+TMAHIWACPP EGDDYIFH HPPEQK+PKPKRLQ+WY KML+K ++E V++++DI+ A + ++ +PT+LPYFEGD+WPN +ED +E +EE R++K + + KK K K + K+ GS T N+V+ K+ EK KE FF IRL S Q++ A L PI+DPD L SD+MDGRD L ARE+H EFSSLRRAK+STLC Y LH + Y CN C+ + C+ C+DF+LC C T HPH + K+ +++ + T + R SL HACQCRD NCR C KMK +++H + C TC +C+ + +C HAK C+ C VP C+ +R
Sbjct: 399 DPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTSCNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCKPLKRIQDTPLQFSLPDLANLIGVNGNSNGSAEGDGLHQFGSPAMRTGNITNSLFEGFNGNPFQNGPNRGGPRPPGGNGEIPNLPPPDMPDCTKEWH-HQVTKDLRNHL----VGKLVKAIFPEPNQEAMNDNRLKDLIAYARKVEKEMFESANDREEYYHLLAEKIYKIQKELQEKKNSRLNQGAAAHDQYAIPPS--NELAQMLGVEGGRSDVHSEGSSMAVAPSQQNQPWGGAPNSNMHQQIPPNGQVPQVNNSSTFPSSGNSTPNIGASSTVSAMLQPKTEPMDDQNTDS----LSSRPPTAIGFGGSSSSTPAPIMNGIVKKEEDPEESSNQAPPSVKDTKDGVAESKPKEQQAKREPTPPPTEDTVFSQEDLIKFLLPVWEKLDKSEDAAPFRVPVDAKLLNIPDYHEIIKRPMDLETVHKKLYAGQYQNAGQFCDDIWLMLDNAWLYNRKNSKVYKYGLKLSEMFVSEMDPVMKSMGYCCAKKLAFTPLSLFCYGAAMCTIAREQQYWVFEQSSTQYNVTVTE----RYTYCQKCFDALPPEGISLSENPNDRNNMAPKTSFTEQKNSVIDYEPFERCKYCMRKWHRICALHDKKVYPEGFICECCRTAKKYQKPDNKYLASKLPHNKLSTFLEDRVNGFIKKQLQAEAHKYPVIIRTLCVQDKEAEVKAQMKQKYVESNQFPEKFPYRTKAVFAFEIIDGVEVCFFGLHVQEYGSACPAPNARRVYIAYLDSVHFFQPRELRTDVYHELLLGYLDYAKMLGYTMAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQDWYKKMLEKGVQEGSVVEFKDIYKQARDDNLTTPTQLPYFEGDFWPNVIEDCIREASNEEAQRKVKEDD--------DDGEDADGGLGGGDSGKKKSSKNKKNNLKKNAKMNKKKAGSITGNEVADKLYSQFEKHKEVFFTIRLVSLQNEPAVLAKPISDPDGLMQSDMMDGRDTFLTKAREEHWEFSSLRRAKYSTLCLAYSLHETDSKGMEYTCNKCSS--PAVWHCQSCDDFDLCDGCKPTTQHPHEMEKI-----KSLIGGGEAGDSAAGGTRYESIQRCIASLVHACQCRDANCRRMSCHKMKRVVQHTKMCKKRINGTCPVCKQLIALCCYHAKHCTRDACTVPFCMNIR 1621
BLAST of CREB-binding protein vs. Ensembl Celegans
Match: cbp-1 (pep chromosome:WBcel235:III:9766516:9774807:1 gene:WBGene00000366.1 transcript:R10E11.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cbp-1) HSP 1 Score: 711.449 bits (1835), Expect = 0.000e+0 Identity = 444/1253 (35.43%), Postives = 638/1253 (50.92%), Query Frame = 3
Query: 114 DSDKRFLIRQQLYYLFHASKCTRLAYTTGKGDCHNQ----------HCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR-----PNNNIRKSVSNKPKINGITNYN------DQFNND--KEVNWRNTIL---------------------------SIRPNFLVKLTDELIPVKVCEDVKNHSGYIDVSNYVKSFEFEIFQKAININ------------------------DYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGN------MKDNLEFGTIKKELVANEIP-------------------MTPDKEYEQKLAYGSYIKTESWTENDIDSKRELLESSP------NAAAKSTPVKL-------------PATQLSTDVKMSPDSTSTPNKDHTNAHKK----------WSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDR---DPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEI-DEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHS-QSDAANLP-PINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCSIP-KSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLR 3467
D +KR LI+QQL L HA KC++ NQ HC M+ V+ H+T C G+ C F HC SS++II HWKNC+ +C VC PL+ P ++N +NG +N + QF + + N N++ ++ P + T E +V +D++NH V VK+ E Q+A+N N +Y + LAEK + + L K+N + N+ AH+ P + Q++ E + + +G+ + N +G + +IP TP+ ++ KTE + + DS L S P ++ STP + + Q VK + D + A ++ +S E+L + + + + +D+ PF++PV+ +LL+IPDY I+K PMDL T+ KL G Y N DD WLM +NAWLYN+K SKVYK L+++F S++D +M S G+CC ++ + P L C +C I R+ Y+ F+ + ++E RY C+KC++ + ++ N K+ ++ +N+V + E F C+ C RKWH++CA H ++ +GF C C K + N Y + LPH +LS ++E+RVN ++K + + VI+R L DK EVK MK Y E+ + PE F YR KAVFAF+ IDG EVCFFGLHVQEYGS CP PN+RRVY+AYLDSVHFF PR+ RTDVYHE L+GYL+YAK LG+TMAHIWACPP EGDDYIFH HPPEQK+PKPKRLQ+WY KML+K ++E V++++DI+ A + ++ +PT+LPYFEGD+WPN +ED +E +EE R++K + + KK K K + K+ GS T N+V+ K+ EK KE FF IRL S Q++ A L PI+DPD L SD+MDGRD L ARE+H EFSSLRRAK+STLC Y LH + Y CN C+ + C+ C+DF+LC C T HPH + K+ +++ + T + R SL HACQCRD NCR C KMK +++H + C TC +C+ + +C HAK C+ C VP C+ +R
Sbjct: 399 DPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTSCNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCKPLKRIQDTPLQFSLPDLANLIGVNGNSNGSAEGDGLHQFGSPAMRTGNITNSLFEGFNGNPFQNGPNRGGPRPPGGNGEIPNLPPPDMPDCTKEWH-HQVTKDLRNHL----VGKLVKAIFPEPNQEAMNDNRLKDLIAYARKVEKEMFESANDREEYYHLLAEKIYKIQKELQEKKNSRLNQGAAAHDQYAIPPS--NELAQMLGVEGGRSDVHSEGSSMAVAPSQQNQPWGGAPNSNMHQQIPPNGQVPQVNNSSTFPSSGNSTPNIGASSTVSAMLQPKTEPMDDQNTDS----LSSRPPTAIGFGGSSSSTPAPIMNGIVKKEEDPEESSNQAPPSVKDTKDGVAESKPKEQQAKREPTPPPTEDTVFSQEDLIKFLLPVWEKLDKSEDAAPFRVPVDAKLLNIPDYHEIIKRPMDLETVHKKLYAGQYQNAGQFCDDIWLMLDNAWLYNRKNSKVYKYGLKLSEMFVSEMDPVMKSMGYCCAKKLAFTPLSLFCYGAAMCTIAREQQYWVFEQSSTQYNVTVTE----RYTYCQKCFDALPPEGISLSENPNDRNNMAPKTSFTEQKNSVIDYEPFERCKYCMRKWHRICALHDKKVYPEGFICECCRTAKKYQKPDNKYLASKLPHNKLSTFLEDRVNGFIKKQLQAEAHKYPVIIRTLCVQDKEAEVKAQMKQKYVESNQFPEKFPYRTKAVFAFEIIDGVEVCFFGLHVQEYGSACPAPNARRVYIAYLDSVHFFQPRELRTDVYHELLLGYLDYAKMLGYTMAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQDWYKKMLEKGVQEGSVVEFKDIYKQARDDNLTTPTQLPYFEGDFWPNVIEDCIREASNEEAQRKVKEDD--------DDGEDADGGLGGGDSGKKKSSKNKKNNLKKNAKMNKKKAGSITGNEVADKLYSQFEKHKEVFFTIRLVSLQNEPAVLAKPISDPDGLMQSDMMDGRDTFLTKAREEHWEFSSLRRAKYSTLCLAYSLHETDSKGMEYTCNKCSS--PAVWHCQSCDDFDLCDGCKPTTQHPHEMEKI-----KSLIGGGEAGDSAAGGTRYESIQRCIASLVHACQCRDANCRRMSCHKMKRVVQHTKMCKKRINGTCPVCKQLIALCCYHAKHCTRDACTVPFCMNIR 1621
BLAST of CREB-binding protein vs. Ensembl Celegans
Match: cbp-1 (pep chromosome:WBcel235:III:9766516:9774807:1 gene:WBGene00000366.1 transcript:R10E11.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cbp-1) HSP 1 Score: 703.36 bits (1814), Expect = 0.000e+0 Identity = 444/1264 (35.13%), Postives = 638/1264 (50.47%), Query Frame = 3
Query: 114 DSDKRFLIRQQLYYLFHASKCTRLAYTTGKGDCHNQ----------HCIMMRSVVKHITKC-----------QSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR-----PNNNIRKSVSNKPKINGITNYN------DQFNND--KEVNWRNTIL---------------------------SIRPNFLVKLTDELIPVKVCEDVKNHSGYIDVSNYVKSFEFEIFQKAININ------------------------DYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGN------MKDNLEFGTIKKELVANEIP-------------------MTPDKEYEQKLAYGSYIKTESWTENDIDSKRELLESSP------NAAAKSTPVKL-------------PATQLSTDVKMSPDSTSTPNKDHTNAHKK----------WSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDR---DPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEI-DEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHS-QSDAANLP-PINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCSIP-KSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLR 3467
D +KR LI+QQL L HA KC++ NQ HC M+ V+ H+T C Q+ K C HC SS++II HWKNC+ +C VC PL+ P ++N +NG +N + QF + + N N++ ++ P + T E +V +D++NH V VK+ E Q+A+N N +Y + LAEK + + L K+N + N+ AH+ P + Q++ E + + +G+ + N +G + +IP TP+ ++ KTE + + DS L S P ++ STP + + Q VK + D + A ++ +S E+L + + + + +D+ PF++PV+ +LL+IPDY I+K PMDL T+ KL G Y N DD WLM +NAWLYN+K SKVYK L+++F S++D +M S G+CC ++ + P L C +C I R+ Y+ F+ + ++E RY C+KC++ + ++ N K+ ++ +N+V + E F C+ C RKWH++CA H ++ +GF C C K + N Y + LPH +LS ++E+RVN ++K + + VI+R L DK EVK MK Y E+ + PE F YR KAVFAF+ IDG EVCFFGLHVQEYGS CP PN+RRVY+AYLDSVHFF PR+ RTDVYHE L+GYL+YAK LG+TMAHIWACPP EGDDYIFH HPPEQK+PKPKRLQ+WY KML+K ++E V++++DI+ A + ++ +PT+LPYFEGD+WPN +ED +E +EE R++K + + KK K K + K+ GS T N+V+ K+ EK KE FF IRL S Q++ A L PI+DPD L SD+MDGRD L ARE+H EFSSLRRAK+STLC Y LH + Y CN C+ + C+ C+DF+LC C T HPH + K+ +++ + T + R SL HACQCRD NCR C KMK +++H + C TC +C+ + +C HAK C+ C VP C+ +R
Sbjct: 399 DPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTSCNVGRLCHSDTTQTTKKCSVAHCASSRQIIAHWKNCSREDCPVCKPLKRIQDTPLQFSLPDLANLIGVNGNSNGSAEGDGLHQFGSPAMRTGNITNSLFEGFNGNPFQNGPNRGGPRPPGGNGEIPNLPPPDMPDCTKEWH-HQVTKDLRNHL----VGKLVKAIFPEPNQEAMNDNRLKDLIAYARKVEKEMFESANDREEYYHLLAEKIYKIQKELQEKKNSRLNQGAAAHDQYAIPPS--NELAQMLGVEGGRSDVHSEGSSMAVAPSQQNQPWGGAPNSNMHQQIPPNGQVPQVNNSSTFPSSGNSTPNIGASSTVSAMLQPKTEPMDDQNTDS----LSSRPPTAIGFGGSSSSTPAPIMNGIVKKEEDPEESSNQAPPSVKDTKDGVAESKPKEQQAKREPTPPPTEDTVFSQEDLIKFLLPVWEKLDKSEDAAPFRVPVDAKLLNIPDYHEIIKRPMDLETVHKKLYAGQYQNAGQFCDDIWLMLDNAWLYNRKNSKVYKYGLKLSEMFVSEMDPVMKSMGYCCAKKLAFTPLSLFCYGAAMCTIAREQQYWVFEQSSTQYNVTVTE----RYTYCQKCFDALPPEGISLSENPNDRNNMAPKTSFTEQKNSVIDYEPFERCKYCMRKWHRICALHDKKVYPEGFICECCRTAKKYQKPDNKYLASKLPHNKLSTFLEDRVNGFIKKQLQAEAHKYPVIIRTLCVQDKEAEVKAQMKQKYVESNQFPEKFPYRTKAVFAFEIIDGVEVCFFGLHVQEYGSACPAPNARRVYIAYLDSVHFFQPRELRTDVYHELLLGYLDYAKMLGYTMAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQDWYKKMLEKGVQEGSVVEFKDIYKQARDDNLTTPTQLPYFEGDFWPNVIEDCIREASNEEAQRKVKEDD--------DDGEDADGGLGGGDSGKKKSSKNKKNNLKKNAKMNKKKAGSITGNEVADKLYSQFEKHKEVFFTIRLVSLQNEPAVLAKPISDPDGLMQSDMMDGRDTFLTKAREEHWEFSSLRRAKYSTLCLAYSLHETDSKGMEYTCNKCSS--PAVWHCQSCDDFDLCDGCKPTTQHPHEMEKI-----KSLIGGGEAGDSAAGGTRYESIQRCIASLVHACQCRDANCRRMSCHKMKRVVQHTKMCKKRINGTCPVCKQLIALCCYHAKHCTRDACTVPFCMNIR 1632
BLAST of CREB-binding protein vs. Ensembl Celegans
Match: cbp-2 (CBP/p300 homolog [Source:UniProtKB/TrEMBL;Acc:G5EBG3]) HSP 1 Score: 83.5741 bits (205), Expect = 1.010e-16 Identity = 63/218 (28.90%), Postives = 101/218 (46.33%), Query Frame = 3
Query: 165 ASKCTRLAYTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNIRKSVSNKPKINGI-TNYNDQFNNDKEVNWRNTILSIRPNFLV-----KLTDELIPVK-------VCEDVKNH-SGYI-----------------DVSNYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENES 725
A++ L +TT C HC M+ V+ H+T C G+ C F HC SS++II HWKNC+ +C VC PL+ ++ S N I T N + D EV + + ++ + L +PV+ V D++NH G + D++ Y + E E+F+ AI+ +Y + LAEK + + L K+N + N+
Sbjct: 38 AARNQPLPHTT----CRLPHCPTMKEVLIHMTNCNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCTPLKRARDVPLIFSLPHLANLIGTKGNSYGSADGEVVHQIGVSTMSAGRITNGNISNLPPPNVPVRTKEWHRQVTNDLRNHIVGKLVKAICPAPEMMNDIRLKDLNAYARKVEKEVFETAIDRKNYYHLLAEKIYEIQKELQEKKNSRLNQG 251
BLAST of CREB-binding protein vs. Ensembl Fly
Match: nej (gene:FBgn0261617 transcript:FBtr0071402) HSP 1 Score: 759.985 bits (1961), Expect = 0.000e+0 Identity = 398/849 (46.88%), Postives = 535/849 (63.02%), Query Frame = 3
Query: 1089 TPNKDHTNAHKKWSSEEL-SDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQND-KSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNS--------QEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKV--DPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHP---ETPCPTSVP 3587
PN +++ EEL + L + +L + +S PF+ PV+ + L IPDY IVK PMDL TI+ + NG Y++PW+ VDD WLMF+NAWLYN+KTS+VY+ C+ L+++FE++ID +M + G+CCGR++ + PQVL C +C I RDA YY++QN K G + +RY C+KC+ND D + + + +++K + +N+ E E FV C+ C RK H++C +D IW GF C C+++K+ K K N + +K LP +L YIE RVN +LK ++ EV +RV+SSSDK VEVKPGM+ + E EM F YR KA+FAF+E+DG +VCFFG+HVQEYGS+CP PN+RRVY+AYLDSVHFF PR+YRT VYHE L+GY++Y K+LG+TMAHIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDK + E ++ DY+DI A+ + S ELPYFEGD+WPN LE+ KE+D+E + K + +E E S K K K + +R NS K+ N + ND+S K+ MEK KE FFVIRLHS AA+L PI DPD L DLMDGRD L LAR+KH EFSSLRRA+FSTL YELH + ++ +Y CN C +E RY C C+DF+LC C H H + K+ D D+ S + + + Q ++ + + R +SL HACQCRD NCR+ C KMK +++H + C P C +C+ + +C HAK C + KC VP C ++ KQQ SQQ+ QQ Q+LRRRVALM R P + P S P
Sbjct: 1685 APNAGDKKKKCQFNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIPDYFEIVKKPMDLGTIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVFEAEIDPVMQALGYCCGRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNSLKEYG------VASNRYTYCQKCFNDIQGDTVTLGDDPLQSQTQIKKDQFKEMKNDHLELEPFVNCQECGRKQHQICVLWLDSIWPGGFVCDNCLKKKNSKRKENKFNAKRLPTTKLGVYIETRVNNFLKKKEAGAGEVHIRVVSSSDKCVEVKPGMRRRFVEQGEMMNEFPYRAKALFAFEEVDGIDVCFFGMHVQEYGSECPAPNTRRVYIAYLDSVHFFRPRQYRTAVYHEILLGYMDYVKQLGYTMAHIWACPPSEGDDYIFHCHPTDQKIPKPKRLQEWYKKMLDKGMIERIIQDYKDILKQAMEDKLGSAAELPYFEGDFWPNVLEESIKELDQEEEEKRKQAEAAEAAAAANLFSIEENEVSGDGKKKG--QKKAKKSNKSKAAQRKNS-----KKSNEHQSGNDLSTKIYATMEKHKEVFFVIRLHSAQSAASLAPIQDPDPLLTCDLMDGRDAFLTLARDKHFEFSSLRRAQFSTLSMLYELHNQGQDKFVYTCNHCKTAVETRYHCTVCDDFDLCIVCKEKVGHQHKMEKLGFDIDDGSALADHK---QANPQEARKQSIQRCIQSLAHACQCRDANCRLPSCQKMKLVVQHTKNCKRKPNGGCPICKQLIALCCYHAKNCEEQKCPVPFCPNIKHKLKQQQSQQKFQQQQLLRRRVALMSRTAAPAALQGPAAVSGP 2517 HSP 2 Score: 65.4698 bits (158), Expect = 5.170e-10 Identity = 36/94 (38.30%), Postives = 55/94 (58.51%), Query Frame = 3
Query: 111 VDSDKRFLIRQQLYYLFHASKCTRLA-YTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNI 389
V D++ I+QQL L HA KC R + C+ +C M+SV+ H+ C+ KDC QHC SS++I+ H+K C + C +C P R N+++
Sbjct: 507 VPDDRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHMGTCKQSKDCTMQHCASSRQILLHYKTCQNSGCVICYPFRQNHSV 600
BLAST of CREB-binding protein vs. Ensembl Fly
Match: nej (gene:FBgn0261617 transcript:FBtr0302723) HSP 1 Score: 759.985 bits (1961), Expect = 0.000e+0 Identity = 398/849 (46.88%), Postives = 535/849 (63.02%), Query Frame = 3
Query: 1089 TPNKDHTNAHKKWSSEEL-SDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQND-KSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNS--------QEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKV--DPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHP---ETPCPTSVP 3587
PN +++ EEL + L + +L + +S PF+ PV+ + L IPDY IVK PMDL TI+ + NG Y++PW+ VDD WLMF+NAWLYN+KTS+VY+ C+ L+++FE++ID +M + G+CCGR++ + PQVL C +C I RDA YY++QN K G + +RY C+KC+ND D + + + +++K + +N+ E E FV C+ C RK H++C +D IW GF C C+++K+ K K N + +K LP +L YIE RVN +LK ++ EV +RV+SSSDK VEVKPGM+ + E EM F YR KA+FAF+E+DG +VCFFG+HVQEYGS+CP PN+RRVY+AYLDSVHFF PR+YRT VYHE L+GY++Y K+LG+TMAHIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDK + E ++ DY+DI A+ + S ELPYFEGD+WPN LE+ KE+D+E + K + +E E S K K K + +R NS K+ N + ND+S K+ MEK KE FFVIRLHS AA+L PI DPD L DLMDGRD L LAR+KH EFSSLRRA+FSTL YELH + ++ +Y CN C +E RY C C+DF+LC C H H + K+ D D+ S + + + Q ++ + + R +SL HACQCRD NCR+ C KMK +++H + C P C +C+ + +C HAK C + KC VP C ++ KQQ SQQ+ QQ Q+LRRRVALM R P + P S P
Sbjct: 1685 APNAGDKKKKCQFNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIPDYFEIVKKPMDLGTIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVFEAEIDPVMQALGYCCGRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNSLKEYG------VASNRYTYCQKCFNDIQGDTVTLGDDPLQSQTQIKKDQFKEMKNDHLELEPFVNCQECGRKQHQICVLWLDSIWPGGFVCDNCLKKKNSKRKENKFNAKRLPTTKLGVYIETRVNNFLKKKEAGAGEVHIRVVSSSDKCVEVKPGMRRRFVEQGEMMNEFPYRAKALFAFEEVDGIDVCFFGMHVQEYGSECPAPNTRRVYIAYLDSVHFFRPRQYRTAVYHEILLGYMDYVKQLGYTMAHIWACPPSEGDDYIFHCHPTDQKIPKPKRLQEWYKKMLDKGMIERIIQDYKDILKQAMEDKLGSAAELPYFEGDFWPNVLEESIKELDQEEEEKRKQAEAAEAAAAANLFSIEENEVSGDGKKKG--QKKAKKSNKSKAAQRKNS-----KKSNEHQSGNDLSTKIYATMEKHKEVFFVIRLHSAQSAASLAPIQDPDPLLTCDLMDGRDAFLTLARDKHFEFSSLRRAQFSTLSMLYELHNQGQDKFVYTCNHCKTAVETRYHCTVCDDFDLCIVCKEKVGHQHKMEKLGFDIDDGSALADHK---QANPQEARKQSIQRCIQSLAHACQCRDANCRLPSCQKMKLVVQHTKNCKRKPNGGCPICKQLIALCCYHAKNCEEQKCPVPFCPNIKHKLKQQQSQQKFQQQQLLRRRVALMSRTAAPAALQGPAAVSGP 2517 HSP 2 Score: 65.4698 bits (158), Expect = 5.170e-10 Identity = 36/94 (38.30%), Postives = 55/94 (58.51%), Query Frame = 3
Query: 111 VDSDKRFLIRQQLYYLFHASKCTRLA-YTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNI 389
V D++ I+QQL L HA KC R + C+ +C M+SV+ H+ C+ KDC QHC SS++I+ H+K C + C +C P R N+++
Sbjct: 507 VPDDRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHMGTCKQSKDCTMQHCASSRQILLHYKTCQNSGCVICYPFRQNHSV 600
BLAST of CREB-binding protein vs. Ensembl Fly
Match: nej (gene:FBgn0261617 transcript:FBtr0302722) HSP 1 Score: 759.599 bits (1960), Expect = 0.000e+0 Identity = 398/849 (46.88%), Postives = 535/849 (63.02%), Query Frame = 3
Query: 1089 TPNKDHTNAHKKWSSEEL-SDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQND-KSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNS--------QEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKV--DPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHP---ETPCPTSVP 3587
PN +++ EEL + L + +L + +S PF+ PV+ + L IPDY IVK PMDL TI+ + NG Y++PW+ VDD WLMF+NAWLYN+KTS+VY+ C+ L+++FE++ID +M + G+CCGR++ + PQVL C +C I RDA YY++QN K G + +RY C+KC+ND D + + + +++K + +N+ E E FV C+ C RK H++C +D IW GF C C+++K+ K K N + +K LP +L YIE RVN +LK ++ EV +RV+SSSDK VEVKPGM+ + E EM F YR KA+FAF+E+DG +VCFFG+HVQEYGS+CP PN+RRVY+AYLDSVHFF PR+YRT VYHE L+GY++Y K+LG+TMAHIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDK + E ++ DY+DI A+ + S ELPYFEGD+WPN LE+ KE+D+E + K + +E E S K K K + +R NS K+ N + ND+S K+ MEK KE FFVIRLHS AA+L PI DPD L DLMDGRD L LAR+KH EFSSLRRA+FSTL YELH + ++ +Y CN C +E RY C C+DF+LC C H H + K+ D D+ S + + + Q ++ + + R +SL HACQCRD NCR+ C KMK +++H + C P C +C+ + +C HAK C + KC VP C ++ KQQ SQQ+ QQ Q+LRRRVALM R P + P S P
Sbjct: 1691 APNAGDKKKKCQFNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIPDYFEIVKKPMDLGTIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVFEAEIDPVMQALGYCCGRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNSLKEYG------VASNRYTYCQKCFNDIQGDTVTLGDDPLQSQTQIKKDQFKEMKNDHLELEPFVNCQECGRKQHQICVLWLDSIWPGGFVCDNCLKKKNSKRKENKFNAKRLPTTKLGVYIETRVNNFLKKKEAGAGEVHIRVVSSSDKCVEVKPGMRRRFVEQGEMMNEFPYRAKALFAFEEVDGIDVCFFGMHVQEYGSECPAPNTRRVYIAYLDSVHFFRPRQYRTAVYHEILLGYMDYVKQLGYTMAHIWACPPSEGDDYIFHCHPTDQKIPKPKRLQEWYKKMLDKGMIERIIQDYKDILKQAMEDKLGSAAELPYFEGDFWPNVLEESIKELDQEEEEKRKQAEAAEAAAAANLFSIEENEVSGDGKKKG--QKKAKKSNKSKAAQRKNS-----KKSNEHQSGNDLSTKIYATMEKHKEVFFVIRLHSAQSAASLAPIQDPDPLLTCDLMDGRDAFLTLARDKHFEFSSLRRAQFSTLSMLYELHNQGQDKFVYTCNHCKTAVETRYHCTVCDDFDLCIVCKEKVGHQHKMEKLGFDIDDGSALADHK---QANPQEARKQSIQRCIQSLAHACQCRDANCRLPSCQKMKLVVQHTKNCKRKPNGGCPICKQLIALCCYHAKNCEEQKCPVPFCPNIKHKLKQQQSQQKFQQQQLLRRRVALMSRTAAPAALQGPAAVSGP 2523 HSP 2 Score: 65.4698 bits (158), Expect = 5.303e-10 Identity = 36/94 (38.30%), Postives = 55/94 (58.51%), Query Frame = 3
Query: 111 VDSDKRFLIRQQLYYLFHASKCTRLA-YTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNI 389
V D++ I+QQL L HA KC R + C+ +C M+SV+ H+ C+ KDC QHC SS++I+ H+K C + C +C P R N+++
Sbjct: 513 VPDDRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHMGTCKQSKDCTMQHCASSRQILLHYKTCQNSGCVICYPFRQNHSV 606
BLAST of CREB-binding protein vs. Ensembl Fly
Match: nej (gene:FBgn0261617 transcript:FBtr0333521) HSP 1 Score: 757.673 bits (1955), Expect = 0.000e+0 Identity = 396/848 (46.70%), Postives = 531/848 (62.62%), Query Frame = 3
Query: 1089 TPNKDHTNAHKKWSSEEL-SDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNS--------QEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKV--DPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHP---ETPCPTSVP 3587
PN +++ EEL + L + +L + +S PF+ PV+ + L IPDY IVK PMDL TI+ + NG Y++PW+ VDD WLMF+NAWLYN+KTS+VY+ C+ L+++FE++ID +M + G+CCGR++ + PQVL C +C I RDA YY++QN RY C+KC+ND D + + + +++K + +N+ E E FV C+ C RK H++C +D IW GF C C+++K+ K K N + +K LP +L YIE RVN +LK ++ EV +RV+SSSDK VEVKPGM+ + E EM F YR KA+FAF+E+DG +VCFFG+HVQEYGS+CP PN+RRVY+AYLDSVHFF PR+YRT VYHE L+GY++Y K+LG+TMAHIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDK + E ++ DY+DI A+ + S ELPYFEGD+WPN LE+ KE+D+E + K + +E E S K K K + +R NS K+ N + ND+S K+ MEK KE FFVIRLHS AA+L PI DPD L DLMDGRD L LAR+KH EFSSLRRA+FSTL YELH + ++ +Y CN C +E RY C C+DF+LC C H H + K+ D D+ S + + + Q ++ + + R +SL HACQCRD NCR+ C KMK +++H + C P C +C+ + +C HAK C + KC VP C ++ KQQ SQQ+ QQ Q+LRRRVALM R P + P S P
Sbjct: 1685 APNAGDKKKKCQFNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIPDYFEIVKKPMDLGTIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVFEAEIDPVMQALGYCCGRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQN---------------RYTYCQKCFNDIQGDTVTLGDDPLQSQTQIKKDQFKEMKNDHLELEPFVNCQECGRKQHQICVLWLDSIWPGGFVCDNCLKKKNSKRKENKFNAKRLPTTKLGVYIETRVNNFLKKKEAGAGEVHIRVVSSSDKCVEVKPGMRRRFVEQGEMMNEFPYRAKALFAFEEVDGIDVCFFGMHVQEYGSECPAPNTRRVYIAYLDSVHFFRPRQYRTAVYHEILLGYMDYVKQLGYTMAHIWACPPSEGDDYIFHCHPTDQKIPKPKRLQEWYKKMLDKGMIERIIQDYKDILKQAMEDKLGSAAELPYFEGDFWPNVLEESIKELDQEEEEKRKQAEAAEAAAAANLFSIEENEVSGDGKKKG--QKKAKKSNKSKAAQRKNS-----KKSNEHQSGNDLSTKIYATMEKHKEVFFVIRLHSAQSAASLAPIQDPDPLLTCDLMDGRDAFLTLARDKHFEFSSLRRAQFSTLSMLYELHNQGQDKFVYTCNHCKTAVETRYHCTVCDDFDLCIVCKEKVGHQHKMEKLGFDIDDGSALADHK---QANPQEARKQSIQRCIQSLAHACQCRDANCRLPSCQKMKLVVQHTKNCKRKPNGGCPICKQLIALCCYHAKNCEEQKCPVPFCPNIKHKLKQQQSQQKFQQQQLLRRRVALMSRTAAPAALQGPAAVSGP 2507 HSP 2 Score: 65.4698 bits (158), Expect = 5.256e-10 Identity = 36/94 (38.30%), Postives = 55/94 (58.51%), Query Frame = 3
Query: 111 VDSDKRFLIRQQLYYLFHASKCTRLA-YTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNI 389
V D++ I+QQL L HA KC R + C+ +C M+SV+ H+ C+ KDC QHC SS++I+ H+K C + C +C P R N+++
Sbjct: 507 VPDDRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHMGTCKQSKDCTMQHCASSRQILLHYKTCQNSGCVICYPFRQNHSV 600
BLAST of CREB-binding protein vs. Ensembl Fly
Match: fs(1)h (gene:FBgn0004656 transcript:FBtr0071119) HSP 1 Score: 79.7221 bits (195), Expect = 2.641e-14 Identity = 40/106 (37.74%), Postives = 62/106 (58.49%), Query Frame = 3
Query: 1128 SSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDI 1445
++ +L L + ++I S PF+ PV+ + L++PDY I+K PMD+ TIK +L N Y + + + DF MFNN ++YNK V M TL K+F KI+ +
Sbjct: 35 NTNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESM 140 HSP 2 Score: 60.8474 bits (146), Expect = 1.568e-8 Identity = 40/112 (35.71%), Postives = 57/112 (50.89%), Query Frame = 3
Query: 1128 SSEELSDLFM---EIHQLILSDKDSE---PFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDI 1445
+ E+LSD EI + + S K S PF PV+ E+L + DY I+K PMDL T+K K+ N Y + + D L+F N + YN V M L +FE + +I
Sbjct: 473 NKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANI 584
BLAST of CREB-binding protein vs. Ensembl Zebrafish
Match: crebbpb (CREB binding protein b [Source:ZFIN;Acc:ZDB-GENE-050302-102]) HSP 1 Score: 764.607 bits (1973), Expect = 0.000e+0 Identity = 406/856 (47.43%), Postives = 536/856 (62.62%), Query Frame = 3
Query: 1068 MSPDSTSTPNKDHTNAHKK-WSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYN-----------DSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQ-RGMHPETPCPTS 3581
+S ++STP + KK + EEL M + L D +S PF+ PV+ LL IPDY IVK P+DLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M G+CCGR++ + PQ L C +C I RD YY++QN RY CEKC+N D + ++++ + + K K +N+ ++E FV C+ C RK H++C H D IW GF C C+++ K N + +K L L YIE+RVNKYLK ++ P EV VRV++SSDK VEVKPGMKS + ++ EM ESF YR KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN+RRVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R K + T +S+ E +Q + + + K + R N +K+ + ND+S+K+ MEK KE FFVI LH+ LPPI DPD L DLMDGRD L LAR+KH EFSSLRR K+ST+C ELH + ++ +Y CN C +E R+ C CEDF+LC +CY ++ H H + K + D++SN N + + +++ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ QQR+QQAQM+RRR+ALMQ RGM P P PT+
Sbjct: 999 VSSTNSSTPANQSAQSRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPNLLGIPDYFDIVKNPIDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQGLGYCCGRKYEFSPQTLCCYGKQLCTISRDGTYYSYQN---------------RYHFCEKCFNEIQGDSVTLGDDPTQSQTYVSSAAQKSLSMISKEQFEKKKNDTLDSEPFVECKDCGRKMHQICVLHYDVIWPSGFICDNCLKKSGKSRKENKFSAKKLQCTRLGSYIEDRVNKYLKRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPFPNTRRVYISYLDSIHFFKPRLLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYRKMLDKAFAERIIHDYKDIFKQATEDRLTSAYELPYFEGDFWPNVLEESIKELEQEEEERKKEEN-TASSETTEGAQADSKNAKKKNNKKTNKNKSSVSRAN-----KKKPGMPNVANDLSQKLYATMEKHKEVFFVIHLHAGPVVNTLPPIMDPDPLLTCDLMDGRDAFLTLARDKHWEFSSLRRCKWSTMCMLVELHNQGQDRFVYTCNECKHHVETRWHCTVCEDFDLCINCYNSKGHEHQMVKWGLGLDDDSN--NQGGEANKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQQRLQQAQMMRRRMALMQGRGMPPSLPSPTT 1831 HSP 2 Score: 83.5741 bits (205), Expect = 2.533e-15 Identity = 48/112 (42.86%), Postives = 62/112 (55.36%), Query Frame = 3
Query: 42 NLKMTSSSEVMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
NL V V + P D +KR LI+QQL L HA KC R G+ C HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 298 NLLQQQVPSVGMVPGQGVSAGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACALPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 409
BLAST of CREB-binding protein vs. Ensembl Zebrafish
Match: ep300a (E1A binding protein p300 a [Source:ZFIN;Acc:ZDB-GENE-080403-16]) HSP 1 Score: 752.281 bits (1941), Expect = 0.000e+0 Identity = 380/789 (48.16%), Postives = 499/789 (63.24%), Query Frame = 3
Query: 1107 TNAHKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
TN K + EEL M + L D +S PF+ PV+ LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR+ + PQ L C +C I RDA Y+++QN L DRY CEKC+N+ + + + + + K K +N+ + E FV C C RK H++C H + IW GF C C+++ + K N Y +K LP +L ++E RVN YLK ++ P EV VRV+ S+K+VEVKPGMKS + ++ EM ESF Y+ KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN RRVY++YLDSVHFF PR RT+VYHE L+GYL+YAK+ GFT HIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDKA+ E VV DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + T N + ET++ + + + K L R N +K+ + ND+S+K+ MEK KE FFVIRL + ++ L PI DPD L DLMDGRD L +AR+KHLEFSSLRR+K+ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+ H H + K + D+ESN + P D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 1046 TNKKKIFKPEELRQALMPTLESLYRQDPESLPFRQPVDPSLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDAAYFSYQNSSPK-----YGLLADRYHFCEKCFNEIQGETVSLGDDPSQPQTSINKDQFEKKKNDTLDPELFVECMDCGRKMHQICVLHNETIWPSGFVCDGCLKKSNKTRKENKYAAKRLPQTKLGNFLETRVNAYLKRQNHPESGEVTVRVVHVSEKMVEVKPGMKSRFVDSGEMSESFPYKSKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFQPRFLRTEVYHEILIGYLDYAKRQGFTTGHIWACPPSEGDDYIFHCHPADQKIPKPKRLQEWYKKMLDKAVAERVVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENSTSN-ESVETTKGDSKNAKKKNNKKTSKNKSSLSRGN-----KKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLFAAPNSNALLPIVDPDPLMACDLMDGRDAFLTIARDKHLEFSSLRRSKWSTMCMLVELHNQSQDRFVYTCNECKHHVETRFHCTVCEDYDLCITCYNTKGHEHKMDKLGLGLDDESNSQVASTTQNPG--DSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1821 HSP 2 Score: 83.1889 bits (204), Expect = 3.424e-15 Identity = 44/91 (48.35%), Postives = 58/91 (63.74%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 343 PAADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 433
BLAST of CREB-binding protein vs. Ensembl Zebrafish
Match: crebbpb (CREB binding protein b [Source:ZFIN;Acc:ZDB-GENE-050302-102]) HSP 1 Score: 750.74 bits (1937), Expect = 0.000e+0 Identity = 405/864 (46.88%), Postives = 535/864 (61.92%), Query Frame = 3
Query: 1068 MSPDSTSTPNKDHTNAHKK-WSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYN-----------DSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVR-YTCKQCE-------DFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQ-RGMHPETPCPTS 3581
+S ++STP + KK + EEL M + L D +S PF+ PV+ LL IPDY IVK P+DLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M G+CCGR++ + PQ L C +C I RD YY++QN RY CEKC+N D + ++++ + + K K +N+ ++E FV C+ C RK H++C H D IW GF C C+++ K N + +K L L YIE+RVNKYLK ++ P EV VRV++SSDK VEVKPGMKS + ++ EM ESF YR KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN+RRVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R K + T +S+ E +Q + + + K + R N +K+ + ND+S+K+ MEK KE FFVI LH+ LPPI DPD L DLMDGRD L LAR+KH EFSSLRR K+ST+C ELH + ++ +Y CN C +E R + C C DF+LC +CY ++ H H + K + D++SN N + + +++ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ QQR+QQAQM+RRR+ALMQ RGM P P PT+
Sbjct: 999 VSSTNSSTPANQSAQSRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPNLLGIPDYFDIVKNPIDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQGLGYCCGRKYEFSPQTLCCYGKQLCTISRDGTYYSYQN---------------RYHFCEKCFNEIQGDSVTLGDDPTQSQTYVSSAAQKSLSMISKEQFEKKKNDTLDSEPFVECKDCGRKMHQICVLHYDVIWPSGFICDNCLKKSGKSRKENKFSAKKLQCTRLGSYIEDRVNKYLKRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPFPNTRRVYISYLDSIHFFKPRLLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYRKMLDKAFAERIIHDYKDIFKQATEDRLTSAYELPYFEGDFWPNVLEESIKELEQEEEERKKEEN-TASSETTEGAQADSKNAKKKNNKKTNKNKSSVSRAN-----KKKPGMPNVANDLSQKLYATMEKHKEVFFVIHLHAGPVVNTLPPIMDPDPLLTCDLMDGRDAFLTLARDKHWEFSSLRRCKWSTMCMLVELHNQGQDRFVYTCNECKHHVETRCFMCYYCPENCINSFDFDLCINCYNSKGHEHQMVKWGLGLDDDSN--NQGGEANKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQQRLQQAQMMRRRMALMQGRGMPPSLPSPTT 1839 HSP 2 Score: 83.5741 bits (205), Expect = 2.514e-15 Identity = 48/112 (42.86%), Postives = 62/112 (55.36%), Query Frame = 3
Query: 42 NLKMTSSSEVMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
NL V V + P D +KR LI+QQL L HA KC R G+ C HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 298 NLLQQQVPSVGMVPGQGVSAGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACALPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 409
BLAST of CREB-binding protein vs. Ensembl Zebrafish
Match: CR354584.4 (E1A binding protein p300 a [Source:NCBI gene;Acc:559273]) HSP 1 Score: 746.503 bits (1926), Expect = 0.000e+0 Identity = 382/798 (47.87%), Postives = 499/798 (62.53%), Query Frame = 3
Query: 1107 TNAHKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYND-SCEDVQFINAENNGAAC--------KVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
TN K + EEL M + L D +S PF+ PV+ LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR+ + PQ L C +C I RDA Y+++QN L DRY CEKC+N+ E V + + + K K +N+ + E FV C C RK H++C H + IW GF C C+++ + K N Y +K LP +L ++E RVN YLK ++ P EV VRV+ S+K+VEVKPGMKS + ++ EM ESF Y+ KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN RRVY++YLDSVHFF PR RT+VYHE L+GYL+YAK+ GFT HIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDKA+ E VV DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + T N + ET++ + + + K L R N +K+ + ND+S+K+ MEK KE FFVIRL + ++ L PI DPD L DLMDGRD L +AR+KHLEFSSLRR+K+ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+ H H + K + D+ESN + P D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 1041 TNKKKIFKPEELRQALMPTLESLYRQDPESLPFRQPVDPSLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDAAYFSYQNSSPK-----YGLLADRYHFCEKCFNEIQGETVSLGDDPSQPQTATIFLNISRSINKDQFEKKKNDTLDPELFVECMDCGRKMHQICVLHNETIWPSGFVCDGCLKKSNKTRKENKYAAKRLPQTKLGNFLETRVNAYLKRQNHPESGEVTVRVVHVSEKMVEVKPGMKSRFVDSGEMSESFPYKSKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFQPRFLRTEVYHEILIGYLDYAKRQGFTTGHIWACPPSEGDDYIFHCHPADQKIPKPKRLQEWYKKMLDKAVAERVVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENSTSN-ESVETTKGDSKNAKKKNNKKTSKNKSSLSRGN-----KKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLFAAPNSNALLPIVDPDPLMACDLMDGRDAFLTIARDKHLEFSSLRRSKWSTMCMLVELHNQSQDRFVYTCNECKHHVETRFHCTVCEDYDLCITCYNTKGHEHKMDKLGLGLDDESNSQVASTTQNPG--DSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1825 HSP 2 Score: 83.1889 bits (204), Expect = 3.122e-15 Identity = 44/91 (48.35%), Postives = 58/91 (63.74%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 339 PAADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 429
BLAST of CREB-binding protein vs. Ensembl Zebrafish
Match: ep300a (E1A binding protein p300 a [Source:ZFIN;Acc:ZDB-GENE-080403-16]) HSP 1 Score: 746.117 bits (1925), Expect = 0.000e+0 Identity = 382/798 (47.87%), Postives = 499/798 (62.53%), Query Frame = 3
Query: 1107 TNAHKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYND-SCEDVQFINAENNGAAC--------KVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
TN K + EEL M + L D +S PF+ PV+ LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR+ + PQ L C +C I RDA Y+++QN L DRY CEKC+N+ E V + + + K K +N+ + E FV C C RK H++C H + IW GF C C+++ + K N Y +K LP +L ++E RVN YLK ++ P EV VRV+ S+K+VEVKPGMKS + ++ EM ESF Y+ KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN RRVY++YLDSVHFF PR RT+VYHE L+GYL+YAK+ GFT HIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDKA+ E VV DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + T N + ET++ + + + K L R N +K+ + ND+S+K+ MEK KE FFVIRL + ++ L PI DPD L DLMDGRD L +AR+KHLEFSSLRR+K+ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+ H H + K + D+ESN + P D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 1045 TNKKKIFKPEELRQALMPTLESLYRQDPESLPFRQPVDPSLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDAAYFSYQNSSPK-----YGLLADRYHFCEKCFNEIQGETVSLGDDPSQPQTATIFLNISRSINKDQFEKKKNDTLDPELFVECMDCGRKMHQICVLHNETIWPSGFVCDGCLKKSNKTRKENKYAAKRLPQTKLGNFLETRVNAYLKRQNHPESGEVTVRVVHVSEKMVEVKPGMKSRFVDSGEMSESFPYKSKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFQPRFLRTEVYHEILIGYLDYAKRQGFTTGHIWACPPSEGDDYIFHCHPADQKIPKPKRLQEWYKKMLDKAVAERVVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENSTSN-ESVETTKGDSKNAKKKNNKKTSKNKSSLSRGN-----KKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLFAAPNSNALLPIVDPDPLMACDLMDGRDAFLTIARDKHLEFSSLRRSKWSTMCMLVELHNQSQDRFVYTCNECKHHVETRFHCTVCEDYDLCITCYNTKGHEHKMDKLGLGLDDESNSQVASTTQNPG--DSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1829 HSP 2 Score: 83.1889 bits (204), Expect = 3.313e-15 Identity = 44/91 (48.35%), Postives = 58/91 (63.74%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 343 PAADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 433
BLAST of CREB-binding protein vs. Ensembl Xenopus
Match: supv3l1 (Suv3 like RNA helicase [Source:Xenbase;Acc:XB-GENE-989015]) HSP 1 Score: 766.918 bits (1979), Expect = 0.000e+0 Identity = 383/802 (47.76%), Postives = 510/802 (63.59%), Query Frame = 3
Query: 1071 SPDSTSTPNKDHTNAHKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
+P + ++P + K + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW V+D WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR+ + PQ L C +C I RDA YY++QN L DRY CEKC+N+ + + + + K SK +N+ + E++V C C RK H++C H + IW GF C C+++ K N + +K LP L ++ENRVN +L+ ++ P EVI+RV+ +SDK VEVKPGMK+ + +T EM ESF YR KA+FAF+E+DG E+CFFG+HVQEYGSDCP PN RRVY++YLDSVHFF P+ RT VYHE L+GYLEY K+LG+T HIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDK++ E V+ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + + S E + K + KK K+ K +SL+ K+ G + ND+S+K+ MEK KE FFVIRL + A +LPPI +PD L DLMDGRD L LAR+KHLEFSSLRRAK+ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+TH H + K + D+ESN N Q + + D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 1060 TPAAQTSPAPPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFEIVKTPMDLSTIKRKLDTGQYQEPWQYVEDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNSSPK-----YGLLADRYHFCEKCFNEIQGECVSLGDDPTQPQTTISKDQFSKRKNDTLDPEQYVECLECGRKMHQICVLHNETIWPTGFVCEGCLKKTGRNRKENKFSAKRLPTTRLGSFLENRVNDFLRRQNNPEAGEVIIRVVHASDKTVEVKPGMKAKFVDTGEMAESFPYRTKALFAFEEVDGVELCFFGMHVQEYGSDCPQPNQRRVYISYLDSVHFFRPKNLRTAVYHEILIGYLEYVKRLGYTAGHIWACPPSEGDDYIFHCHPADQKIPKPKRLQEWYKKMLDKSVSERVIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESIE--------VGKGDSKNAKKKNNKKTSKNKSSLSRGSKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLSAGPAANSLPPIVEPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAKWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKTHEHKMEKLGLGLDDESN--NQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1846 HSP 2 Score: 83.5741 bits (205), Expect = 3.416e-15 Identity = 44/91 (48.35%), Postives = 58/91 (63.74%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 328 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 418
BLAST of CREB-binding protein vs. Ensembl Xenopus
Match: supv3l1 (Suv3 like RNA helicase [Source:Xenbase;Acc:XB-GENE-989015]) HSP 1 Score: 759.599 bits (1960), Expect = 0.000e+0 Identity = 383/809 (47.34%), Postives = 510/809 (63.04%), Query Frame = 3
Query: 1071 SPDSTSTPNKDHTNAHKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIP-------DYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
+P + ++P + K + EEL M + L D +S PF+ PV+ +LL IP DY IVK PMDLSTIK KL G Y PW V+D WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR+ + PQ L C +C I RDA YY++QN L DRY CEKC+N+ + + + + K SK +N+ + E++V C C RK H++C H + IW GF C C+++ K N + +K LP L ++ENRVN +L+ ++ P EVI+RV+ +SDK VEVKPGMK+ + +T EM ESF YR KA+FAF+E+DG E+CFFG+HVQEYGSDCP PN RRVY++YLDSVHFF P+ RT VYHE L+GYLEY K+LG+T HIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDK++ E V+ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + + S E + K + KK K+ K +SL+ K+ G + ND+S+K+ MEK KE FFVIRL + A +LPPI +PD L DLMDGRD L LAR+KHLEFSSLRRAK+ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+TH H + K + D+ESN N Q + + D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 1061 TPAAQTSPAPPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPKNTSVLQDYFEIVKTPMDLSTIKRKLDTGQYQEPWQYVEDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNSSPK-----YGLLADRYHFCEKCFNEIQGECVSLGDDPTQPQTTISKDQFSKRKNDTLDPEQYVECLECGRKMHQICVLHNETIWPTGFVCEGCLKKTGRNRKENKFSAKRLPTTRLGSFLENRVNDFLRRQNNPEAGEVIIRVVHASDKTVEVKPGMKAKFVDTGEMAESFPYRTKALFAFEEVDGVELCFFGMHVQEYGSDCPQPNQRRVYISYLDSVHFFRPKNLRTAVYHEILIGYLEYVKRLGYTAGHIWACPPSEGDDYIFHCHPADQKIPKPKRLQEWYKKMLDKSVSERVIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESIE--------VGKGDSKNAKKKNNKKTSKNKSSLSRGSKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLSAGPAANSLPPIVEPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAKWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKTHEHKMEKLGLGLDDESN--NQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1854 HSP 2 Score: 83.5741 bits (205), Expect = 3.656e-15 Identity = 44/91 (48.35%), Postives = 58/91 (63.74%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 329 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 419
BLAST of CREB-binding protein vs. Ensembl Xenopus
Match: supv3l1 (Suv3 like RNA helicase [Source:Xenbase;Acc:XB-GENE-989015]) HSP 1 Score: 753.436 bits (1944), Expect = 0.000e+0 Identity = 378/784 (48.21%), Postives = 500/784 (63.78%), Query Frame = 3
Query: 1125 WSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
+ EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW V+D WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR+ + PQ L C +C I RDA YY++QN RY CEKC+N+ + + + + K SK +N+ + E++V C C RK H++C H + IW GF C C+++ K N + +K LP L ++ENRVN +L+ ++ P EVI+RV+ +SDK VEVKPGMK+ + +T EM ESF YR KA+FAF+E+DG E+CFFG+HVQEYGSDCP PN RRVY++YLDSVHFF P+ RT VYHE L+GYLEY K+LG+T HIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDK++ E V+ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + + S E + K + KK K+ K +SL+ K+ G + ND+S+K+ MEK KE FFVIRL + A +LPPI +PD L DLMDGRD L LAR+KHLEFSSLRRAK+ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+TH H + K + D+ESN N Q + + D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 882 FKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFEIVKTPMDLSTIKRKLDTGQYQEPWQYVEDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQN---------------RYHFCEKCFNEIQGECVSLGDDPTQPQTTISKDQFSKRKNDTLDPEQYVECLECGRKMHQICVLHNETIWPTGFVCEGCLKKTGRNRKENKFSAKRLPTTRLGSFLENRVNDFLRRQNNPEAGEVIIRVVHASDKTVEVKPGMKAKFVDTGEMAESFPYRTKALFAFEEVDGVELCFFGMHVQEYGSDCPQPNQRRVYISYLDSVHFFRPKNLRTAVYHEILIGYLEYVKRLGYTAGHIWACPPSEGDDYIFHCHPADQKIPKPKRLQEWYKKMLDKSVSERVIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESIE--------VGKGDSKNAKKKNNKKTSKNKSSLSRGSKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLSAGPAANSLPPIVEPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAKWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKTHEHKMEKLGLGLDDESN--NQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1640 HSP 2 Score: 83.1889 bits (204), Expect = 4.873e-15 Identity = 44/91 (48.35%), Postives = 58/91 (63.74%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 299 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 389
BLAST of CREB-binding protein vs. Ensembl Xenopus
Match: supv3l1 (Suv3 like RNA helicase [Source:Xenbase;Acc:XB-GENE-989015]) HSP 1 Score: 753.436 bits (1944), Expect = 0.000e+0 Identity = 378/784 (48.21%), Postives = 500/784 (63.78%), Query Frame = 3
Query: 1125 WSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
+ EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW V+D WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR+ + PQ L C +C I RDA YY++QN RY CEKC+N+ + + + + K SK +N+ + E++V C C RK H++C H + IW GF C C+++ K N + +K LP L ++ENRVN +L+ ++ P EVI+RV+ +SDK VEVKPGMK+ + +T EM ESF YR KA+FAF+E+DG E+CFFG+HVQEYGSDCP PN RRVY++YLDSVHFF P+ RT VYHE L+GYLEY K+LG+T HIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDK++ E V+ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + + S E + K + KK K+ K +SL+ K+ G + ND+S+K+ MEK KE FFVIRL + A +LPPI +PD L DLMDGRD L LAR+KHLEFSSLRRAK+ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+TH H + K + D+ESN N Q + + D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 859 FKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFEIVKTPMDLSTIKRKLDTGQYQEPWQYVEDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQN---------------RYHFCEKCFNEIQGECVSLGDDPTQPQTTISKDQFSKRKNDTLDPEQYVECLECGRKMHQICVLHNETIWPTGFVCEGCLKKTGRNRKENKFSAKRLPTTRLGSFLENRVNDFLRRQNNPEAGEVIIRVVHASDKTVEVKPGMKAKFVDTGEMAESFPYRTKALFAFEEVDGVELCFFGMHVQEYGSDCPQPNQRRVYISYLDSVHFFRPKNLRTAVYHEILIGYLEYVKRLGYTAGHIWACPPSEGDDYIFHCHPADQKIPKPKRLQEWYKKMLDKSVSERVIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESIE--------VGKGDSKNAKKKNNKKTSKNKSSLSRGSKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLSAGPAANSLPPIVEPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAKWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKTHEHKMEKLGLGLDDESN--NQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1617 HSP 2 Score: 84.3445 bits (207), Expect = 1.943e-15 Identity = 48/111 (43.24%), Postives = 65/111 (58.56%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNIRKSVSNKPKINGITN 434
P D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+ N +++ S P G
Sbjct: 329 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK-NAGDKRNQSKSPGAVGTVG 438
BLAST of CREB-binding protein vs. Ensembl Xenopus
Match: supv3l1 (Suv3 like RNA helicase [Source:Xenbase;Acc:XB-GENE-989015]) HSP 1 Score: 752.666 bits (1942), Expect = 0.000e+0 Identity = 378/781 (48.40%), Postives = 499/781 (63.89%), Query Frame = 3
Query: 1134 EELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW V+D WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR+ + PQ L C +C I RDA YY++QN RY CEKC+N+ + + + + K SK +N+ + E++V C C RK H++C H + IW GF C C+++ K N + +K LP L ++ENRVN +L+ ++ P EVI+RV+ +SDK VEVKPGMK+ + +T EM ESF YR KA+FAF+E+DG E+CFFG+HVQEYGSDCP PN RRVY++YLDSVHFF P+ RT VYHE L+GYLEY K+LG+T HIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDK++ E V+ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + + S E + K + KK K+ K +SL+ K+ G + ND+S+K+ MEK KE FFVIRL + A +LPPI +PD L DLMDGRD L LAR+KHLEFSSLRRAK+ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+TH H + K + D+ESN N Q + + D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 884 EELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFEIVKTPMDLSTIKRKLDTGQYQEPWQYVEDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQN---------------RYHFCEKCFNEIQGECVSLGDDPTQPQTTISKDQFSKRKNDTLDPEQYVECLECGRKMHQICVLHNETIWPTGFVCEGCLKKTGRNRKENKFSAKRLPTTRLGSFLENRVNDFLRRQNNPEAGEVIIRVVHASDKTVEVKPGMKAKFVDTGEMAESFPYRTKALFAFEEVDGVELCFFGMHVQEYGSDCPQPNQRRVYISYLDSVHFFRPKNLRTAVYHEILIGYLEYVKRLGYTAGHIWACPPSEGDDYIFHCHPADQKIPKPKRLQEWYKKMLDKSVSERVIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESIE--------VGKGDSKNAKKKNNKKTSKNKSSLSRGSKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLSAGPAANSLPPIVEPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAKWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKTHEHKMEKLGLGLDDESN--NQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1639 HSP 2 Score: 83.1889 bits (204), Expect = 3.855e-15 Identity = 48/109 (44.04%), Postives = 65/109 (59.63%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNIR---KSVSNKPKI 419
P D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+ + R KS+ P +
Sbjct: 287 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQSKSLLGGPPV 395
BLAST of CREB-binding protein vs. Ensembl Mouse
Match: Crebbp (CREB binding protein [Source:MGI Symbol;Acc:MGI:1098280]) HSP 1 Score: 752.666 bits (1942), Expect = 0.000e+0 Identity = 403/854 (47.19%), Postives = 530/854 (62.06%), Query Frame = 3
Query: 1053 STDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK----VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHPET--PCPTSVP 3587
S D S S P K K + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR++ + PQ L C +C I RDA YY++QN RY CEKC+ + + + + + + K K +N+ + E FV C+ C RK H++C H D IW GF C C+++ K N + +K L L ++E+RVNK+L+ ++ P EV VRV++SSDK VEVKPGMKS + ++ EM ESF YR KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN+RRVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R K S T S+ E SQ + + + K + R N +K+ + + ND+S+K+ MEK KE FFVI LH+ + PPI DPD L DLMDGRD L LAR+KH EFSSLRR+K+STLC ELH + ++ +Y CN C +E R+ C CED++LC +CY T++H H + K +D DE S+ Q+ S +++ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQ++RRR+A M P+ P PTS P
Sbjct: 1030 SNDTASQSTSPSQPRK------KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQN---------------RYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEES-TAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRAN-----KKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLD-DEGSSQGEPQSKS---PQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAP 1852
BLAST of CREB-binding protein vs. Ensembl Mouse
Match: Crebbp (CREB binding protein [Source:MGI Symbol;Acc:MGI:1098280]) HSP 1 Score: 751.895 bits (1940), Expect = 0.000e+0 Identity = 403/854 (47.19%), Postives = 530/854 (62.06%), Query Frame = 3
Query: 1053 STDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK----VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHPET--PCPTSVP 3587
S D S S P K K + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR++ + PQ L C +C I RDA YY++QN RY CEKC+ + + + + + + K K +N+ + E FV C+ C RK H++C H D IW GF C C+++ K N + +K L L ++E+RVNK+L+ ++ P EV VRV++SSDK VEVKPGMKS + ++ EM ESF YR KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN+RRVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R K S T S+ E SQ + + + K + R N +K+ + + ND+S+K+ MEK KE FFVI LH+ + PPI DPD L DLMDGRD L LAR+KH EFSSLRR+K+STLC ELH + ++ +Y CN C +E R+ C CED++LC +CY T++H H + K +D DE S+ Q+ S +++ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQ++RRR+A M P+ P PTS P
Sbjct: 1068 SNDTASQSTSPSQPRK------KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQN---------------RYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEES-TAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRAN-----KKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLD-DEGSSQGEPQSKS---PQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAP 1890 HSP 2 Score: 82.4185 bits (202), Expect = 5.275e-15 Identity = 44/91 (48.35%), Postives = 57/91 (62.64%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 343 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLK 433
BLAST of CREB-binding protein vs. Ensembl Mouse
Match: Ep300 (E1A binding protein p300 [Source:MGI Symbol;Acc:MGI:1276116]) HSP 1 Score: 748.043 bits (1930), Expect = 0.000e+0 Identity = 399/874 (45.65%), Postives = 535/874 (61.21%), Query Frame = 3
Query: 897 PDKEYEQKLAYGSYIKTESWTENDIDSKRELLESSP--NAAAKSTPVKLPATQ-------LSTDVKM---SPDSTSTPNKDHTNAHKK--WSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
P+K+ Q+ +K ES E D K E ++ P AK VK+ T+ L TD K P +++T + KK + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW +DD WLMFNNAWLYN+KTS+VYK CS L+++FE +ID +M S G+CCGR+ + PQ L C +C I RDA YY++QN RY CEKC+N+ + + + + + K SK +N+ + E FV C C RK H++C H + IW GF C C+++ + K N +K LP L ++ENRVN +L+ ++ P EV VRV+ +SDK VEVKPGMK+ + ++ EM ESF YR KA+FAF+EIDG ++CFFG+HVQEYGSDCP PN RRVY++YLDSVHFF P+ RT VYHE L+GYLEY KKLG+T HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA+ E +V DY+DI A + S ELPYFEGD+WPN LE+ KE+++E R + + ++++ ++K + KK K+ K +SL+ K+ G + ND+S+K+ MEK KE FFVIRL + +LPPI DPD L DLMDGRD L LAR+KHLEFSSLRRA++ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+ H H + K + D+ESN N Q + + D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 967 PEKQPSQE------VKMESKMEVD---KPEPADAQPEDTKEAKGEDVKVEPTEMEERGPELKTDGKEEEEQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYIDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQN---------------RYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPSGFVCDGCLKKTARTRKENKLSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREEN--------TSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIACPAPNSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESN--NQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1806 HSP 2 Score: 82.4185 bits (202), Expect = 5.631e-15 Identity = 44/89 (49.44%), Postives = 57/89 (64.04%), Query Frame = 3
Query: 111 VDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQSGK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 331 ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 419
BLAST of CREB-binding protein vs. Ensembl Mouse
Match: Crebbp (CREB binding protein [Source:MGI Symbol;Acc:MGI:1098280]) HSP 1 Score: 565.459 bits (1456), Expect = 3.145e-177 Identity = 269/514 (52.33%), Postives = 339/514 (65.95%), Query Frame = 3
Query: 1053 STDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEE 2588
S D S S P K K + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR++ + PQ L C +C I RDA YY++QN L DRY CEKC+ + + + + + + K K +N+ + E FV C+ C RK H++C H D IW GF C C+++ K N + +K L L ++E+RVNK+L+ ++ P EV VRV++SSDK VEVKPGMKS + ++ EM ESF YR KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN+RRVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E
Sbjct: 604 SNDTASQSTSPSQPRK------KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNSSPK-----YGLLADRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQE 1106
BLAST of CREB-binding protein vs. Ensembl Mouse
Match: Crebbp (CREB binding protein [Source:MGI Symbol;Acc:MGI:1098280]) HSP 1 Score: 197.208 bits (500), Expect = 2.493e-57 Identity = 103/207 (49.76%), Postives = 126/207 (60.87%), Query Frame = 3
Query: 2037 KSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRL----KSYSETPNSQEGET 2645
KS + ++ EM ESF YR KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN+R V HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + SETP +G++
Sbjct: 2 KSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRYV--------------------------------------TGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETPEGSQGDS 170
BLAST of CREB-binding protein vs. UniProt/SwissProt
Match: sp|Q09472|EP300_HUMAN (Histone acetyltransferase p300 OS=Homo sapiens OX=9606 GN=EP300 PE=1 SV=2) HSP 1 Score: 757.288 bits (1954), Expect = 0.000e+0 Identity = 387/817 (47.37%), Postives = 516/817 (63.16%), Query Frame = 3
Query: 1041 ATQLSTDVKMSPDSTSTPNKDHTNA-----HKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
+T+L T++K D ST + A K + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS L+++FE +ID +M S G+CCGR+ + PQ L C +C I RDA YY++QN RY CEKC+N+ + + + + + K SK +N+ + E FV C C RK H++C H + IW GF C C+++ + K N + +K LP L ++ENRVN +L+ ++ P EV VRV+ +SDK VEVKPGMK+ + ++ EM ESF YR KA+FAF+EIDG ++CFFG+HVQEYGSDCP PN RRVY++YLDSVHFF P+ RT VYHE L+GYLEY KKLG+T HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA+ E +V DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + ++++ ++K + KK K+ K +SL+ K+ G + ND+S+K+ MEK KE FFVIRL + A +LPPI DPD L DLMDGRD L LAR+KHLEFSSLRRA++ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+ H H + K + D+ESN N Q + + D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 1016 STELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQN---------------RYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREEN--------TSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESN--NQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1807 HSP 2 Score: 82.4185 bits (202), Expect = 3.972e-14 Identity = 44/89 (49.44%), Postives = 57/89 (64.04%), Query Frame = 3
Query: 111 VDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQSGK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 330 ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 418
BLAST of CREB-binding protein vs. UniProt/SwissProt
Match: sp|Q92793|CBP_HUMAN (CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3) HSP 1 Score: 753.821 bits (1945), Expect = 0.000e+0 Identity = 398/832 (47.84%), Postives = 524/832 (62.98%), Query Frame = 3
Query: 1119 KKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK----VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHPET--PCPTSVP 3587
K + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR++ + PQ L C +C I RDA YY++QN RY CEKC+ + + + + + + K K +N+ + E FV C+ C RK H++C H D IW GF C C+++ K N + +K L L ++E+RVNK+L+ ++ P EV VRV++SSDK VEVKPGMKS + ++ EM ESF YR KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN+RRVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R K S T S+ E SQ + + + K + R N +K+ + + ND+S+K+ MEK KE FFVI LH+ LPPI DPD L DLMDGRD L LAR+KH EFSSLRR+K+STLC ELH + ++ +Y CN C +E R+ C CED++LC +CY T++H H + K +D DE S+ Q+ S +++ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQ++RRR+A M P+ P PTS P
Sbjct: 1083 KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQN---------------RYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEES-TAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRAN-----KKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLD-DEGSSQGEPQSKS---PQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAP 1889 HSP 2 Score: 82.4185 bits (202), Expect = 3.947e-14 Identity = 44/91 (48.35%), Postives = 57/91 (62.64%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 344 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLK 434
BLAST of CREB-binding protein vs. UniProt/SwissProt
Match: sp|Q6JHU9|CBP_RAT (Histone lysine acetyltransferase CREBBP OS=Rattus norvegicus OX=10116 GN=Crebbp PE=1 SV=1) HSP 1 Score: 751.51 bits (1939), Expect = 0.000e+0 Identity = 397/832 (47.72%), Postives = 524/832 (62.98%), Query Frame = 3
Query: 1119 KKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK----VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHPET--PCPTSVP 3587
K + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR++ + PQ L C +C I RDA YY++QN RY CEKC+ + + + + + + K K +N+ + E FV C+ C RK H++C H D IW GF C C+++ K N + +K L L ++E+RVNK+L+ ++ P EV VRV++SSDK VEVKPGMKS + ++ EM ESF YR KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN+RRVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R K S T S+ E SQ + + + K + R N +K+ + + ND+S+K+ MEK KE FFVI LH+ + PPI DPD L DLMDGRD L LAR+KH EFSSLRR+K+STLC ELH + ++ +Y CN C +E R+ C CED++LC +CY T++H H + K +D DE S+ Q+ S +++ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQ++RRR+A M P+ P PTS P
Sbjct: 1084 KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQN---------------RYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEES-TAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRAN-----KKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLD-DEGSSQGEPQSKS---PQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAP 1890 HSP 2 Score: 82.4185 bits (202), Expect = 3.947e-14 Identity = 44/91 (48.35%), Postives = 57/91 (62.64%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 343 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLK 433
BLAST of CREB-binding protein vs. UniProt/SwissProt
Match: sp|B2RWS6|EP300_MOUSE (Histone acetyltransferase p300 OS=Mus musculus OX=10090 GN=Ep300 PE=1 SV=2) HSP 1 Score: 748.043 bits (1930), Expect = 0.000e+0 Identity = 399/874 (45.65%), Postives = 535/874 (61.21%), Query Frame = 3
Query: 897 PDKEYEQKLAYGSYIKTESWTENDIDSKRELLESSP--NAAAKSTPVKLPATQ-------LSTDVKM---SPDSTSTPNKDHTNAHKK--WSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
P+K+ Q+ +K ES E D K E ++ P AK VK+ T+ L TD K P +++T + KK + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW +DD WLMFNNAWLYN+KTS+VYK CS L+++FE +ID +M S G+CCGR+ + PQ L C +C I RDA YY++QN RY CEKC+N+ + + + + + K SK +N+ + E FV C C RK H++C H + IW GF C C+++ + K N +K LP L ++ENRVN +L+ ++ P EV VRV+ +SDK VEVKPGMK+ + ++ EM ESF YR KA+FAF+EIDG ++CFFG+HVQEYGSDCP PN RRVY++YLDSVHFF P+ RT VYHE L+GYLEY KKLG+T HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA+ E +V DY+DI A + S ELPYFEGD+WPN LE+ KE+++E R + + ++++ ++K + KK K+ K +SL+ K+ G + ND+S+K+ MEK KE FFVIRL + +LPPI DPD L DLMDGRD L LAR+KHLEFSSLRRA++ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+ H H + K + D+ESN N Q + + D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 967 PEKQPSQE------VKMESKMEVD---KPEPADAQPEDTKEAKGEDVKVEPTEMEERGPELKTDGKEEEEQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYIDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQN---------------RYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPSGFVCDGCLKKTARTRKENKLSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREEN--------TSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIACPAPNSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESN--NQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1806 HSP 2 Score: 82.4185 bits (202), Expect = 3.939e-14 Identity = 44/89 (49.44%), Postives = 57/89 (64.04%), Query Frame = 3
Query: 111 VDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQSGK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 331 ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 419
BLAST of CREB-binding protein vs. UniProt/SwissProt
Match: sp|P45481|CBP_MOUSE (Histone lysine acetyltransferase CREBBP OS=Mus musculus OX=10090 GN=Crebbp PE=1 SV=3) HSP 1 Score: 723.776 bits (1867), Expect = 0.000e+0 Identity = 394/854 (46.14%), Postives = 520/854 (60.89%), Query Frame = 3
Query: 1053 STDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK----VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHPET--PCPTSVP 3587
S D S S P K K + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR++ + PQ L C +C I RDA YY++QN RY CEKC+ + + + + + + K K +N+ + E FV C+ C RK H++C H D IW GF C C+++ K N + +K L L ++E+RVNK+L+ ++ P EV VRV++SSDK VEVKPGMKS + ++ EM ESF YR KA+FAF+EIDG +VCFFG+HVQ P RVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R K S T S+ E SQ + + + K + R N +K+ + + ND+S+K+ MEK KE FFVI LH+ + PPI DPD L DLMDGRD L LAR+KH EFSSLRR+K+STLC ELH + ++ +Y CN C +E R+ C CED++LC +CY T++H H + K +D DE S+ Q+ S +++ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQ++RRR+A M P+ P PTS P
Sbjct: 1068 SNDTASQSTSPSQPRK------KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQN---------------RYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQNTALIAPHQIQGRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEES-TAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRAN-----KKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLD-DEGSSQGEPQSKS---PQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAP 1890 HSP 2 Score: 82.4185 bits (202), Expect = 3.784e-14 Identity = 44/91 (48.35%), Postives = 57/91 (62.64%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 343 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLK 433
BLAST of CREB-binding protein vs. TrEMBL
Match: A0A4S2MD36 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000917 PE=4 SV=1) HSP 1 Score: 923.694 bits (2386), Expect = 0.000e+0 Identity = 501/1189 (42.14%), Postives = 699/1189 (58.79%), Query Frame = 3
Query: 132 LIRQQLYYLFHASKCTRLAYTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCA-----------PLRPNNNIR-------KSVSNKP---KINGITNYNDQF-------------NNDKEVNWRNTILSI---RPNFLVKLTDELIPVKVCEDVKNHSGYIDVS-----NYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGNMKDNLEFGTI--KKELVANEIPMTPDKEYEQKLAYGSYIKTESWTENDIDSKRELLE-------SSPNAAAKST------PVKLPATQ------------LSTDVKMSPDSTS----TPNKDHTNAHKKWSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMN---SLNNKRKRING---SDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTS-EDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQC-CSIPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNC 3455
L+++QL L HA +C RL C+ +HC++MR V+ H+ KC C HC SSK I++H+ C+ C VC P P + S +KP +NGI N + + N + N RN+ R + + K + + + N + Y D +++K E +IF K+ +Y L ++ ++ L +R + + N +N IK+E A G ++ E + E+V TP +E A S D + +++ + S+P+ KS+ PV P T+ +S+DVK S + S P ++ +N W EL F+ + I +KD+EPF PV+WE L+I DYP I+ PMDLSTI+ KL N Y +PW VVDDFWLMFNNAWLYNKKTSKVYK C+ LA+ FE+ ID +M GFCCGRE+ YLP L C TP C I RDAVYY ++ND L +Y CE+CYN++ ++++ +++E++ VQK+L+ KC+N+ KE E FVFC+ C RKWH+VCA H D++W +GF C C+R+ +K N Y ++ LP C LS ++E RVN +LK + ++VI+RVL+S+DK VEVKPGMKS +CET +MPESF YR+KA+FAFQEIDGQEVCFFGLHVQEYGS+CP PN+RRVYLAYLDSV+FF P++YRTDVYHE LVGY+ YAK LG+ +AHIWACPP EGDDYIFHMHP +QK+PKPKRLQEWY KML KA+ E +V+DY+DI +A S ++SPTEL YFEGD+WPN LE++FKE+DEE +R + E + ++ + ++ N KK K++ + N SL KRKR+NG +D ++V+R+V E+MEK KENFFVIRLH Q+ ++LP I D D L +SDLM+ R L AREKHLEFSS+RRAK+STL YELH E + ++Y CN CN Q+E + C+QC +++LCP CY TE HPH + ++ + NS S+ + +++ R ++ R K+L H C CRD NCR+ C MK ++HF+ + ++ C +C+ +C+ H+K C + KC VP C
Sbjct: 28 LMQRQLALLLHAERCRRLENDGLTLTCNIRHCMLMRQVLDHMDKCLHEDGCSVAHCRSSKRILRHFNVCSAWSCDVCTAVKRPLIKADIPSHPGTEYQNGPVCNFASSGSKPDTTTMNGIKNPSPHYEVTPTPCSSSPALNGEIGRNNRNSFPLTDEQRKDAMKKFVNVSLSIF---PAANSTAYNDPRMQQFLDHLKRMEKDIFMKSKTAEEYYAALTARYQSIHSELKEQRRLRGARPLEPSNEESN-----------IKNE------AHSGRSSESTEPDRVCDGSEIVCKREDATPVEESRSSPASSSATSFVKSVPMDTAAAQQVNQDCCEQPTSTPSVEIKSSSIDTTQPVTAPTTRSPRDGGANSDVTMSSDVKPSDEPKSEVGQQPLREASN-RAVWYPNELQRYFLPVVDRISKEKDAEPFLQPVDWESLEIYDYPQIITHPMDLSTIRKKLENREYKDPWSVVDDFWLMFNNAWLYNKKTSKVYKTCTKLAEFFETTIDPVMQQLGFCCGREYYYLPPPLTCLTPKFCTIQRDAVYYVYKNDDQ-----TPGLLEQKYTVCERCYNEAGDEIR-LDSESS-TVVTVQKNLMEKCKNDRKEKEPFVFCKKCGRKWHRVCAIHADEVWPEGFVCNRCMRDYGLKRPENRYTARKLPTCRLSNFLEKRVNDFLKKKGTDASDVIIRVLASADKTVEVKPGMKSRFCETGDMPESFPYRVKAIFAFQEIDGQEVCFFGLHVQEYGSECPPPNTRRVYLAYLDSVYFFRPKQYRTDVYHEILVGYIHYAKLLGYAVAHIWACPPSEGDDYIFHMHPTDQKIPKPKRLQEWYQKMLKKALLERIVVDYKDICQEACESGLVSPTELAYFEGDFWPNTLEELFKEMDEEDAKRKREQEALARDDEDDETKENLQTRENEKNPGKKKAKKRKMKRNASLSLPGKRKRLNGGNSADASSEVARRVYEIMEKHKENFFVIRLHPQNSVSSLPAIKDLDPLINSDLMECRGAFLERAREKHLEFSSVRRAKYSTLVMLYELHTENRQPLMYTCNMCNVQLETPWHCRQCVEYDLCPRCYETEKHPHPMVQIGLGLDDGTKNSDVDSEAAAVQESGRDKLSRLVKALGHGCSCRDANCRVFACKTMKSNVQHFRVHAAAARNQCNVCRSLSFLCYYHSKTCQELKCPVPLC 1188
BLAST of CREB-binding protein vs. TrEMBL
Match: A0A4Z2D8G5 (CREB-binding protein isoform 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_003439 PE=4 SV=1) HSP 1 Score: 922.154 bits (2382), Expect = 0.000e+0 Identity = 542/1289 (42.05%), Postives = 741/1289 (57.49%), Query Frame = 3
Query: 42 NLKMTSSSEVMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRP-----------------NNNIRKSVSNKPKINGI-----------TNYNDQFNNDKEVNWRNTILSIRPNFLVKLTD---ELIPVKVCEDVK-------NHSGYIDVS-----NYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTK--------QIEKFFQLIKSEFDKFFIAFKGNMKDNLEFGTIKKELVANEIPMTPDKEYEQKLAYGSYIKTESWTE--NDIDSK----------RELLESSPNAAAKSTPVK-------LPATQLSTDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRR------LKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRING---SDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTT-----RARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCSIPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQR-----GMHPETPCPTSVPLQ-SQTSITSINTQPPSI 3638
+ M SS+ TD+ Q L K L+RQQL L HA C RL +C +++C +RS++ H+ C K+C HC SSK I++H+++C D+EC+VC+ +R N S+ +NGI T + + N +S P ++TD EL K D+ N + Y D +YVK E ++F K+ + +Y +A + ++ L KR +E+ L + ++ T+ E F+ E D+F D LE ++E + EI K+A + + E D D K + PN + T ++ P S + K P ++ P + + W S EL F+ + I +KD+EPF PV+W+ L+I DYP IV PMDLSTI+ KL + Y +PW++VDDFWLM NNAWLYNKKTSKVYK C+ LA+ FES ID +M S GFCCGRE+ Y P L C TP C I RDAVYY + KS+G+ L +Y CE+CYN++ + + + +N VQK+L+ KC+N++KE E FVFC+ C RKWH+VCA ++++IW DGF C CI +K N + +K L C+LS ++E RVN +LK ++ +VI+RVL+++DK VEVK GMK+ +C EMPESF YR+KA+FAFQEIDGQEVCFFGLHVQEYGS+CP PN+RRVY+AYLDSV+FF P+++RT++YHE LVGY+ YAK LGFTMAHIWACPP EGDDYIFHMHPP+QK+PKPKRLQEWY KML KA+ E +V+DY+DI DA S M+SP EL YFEGD+WPN LE+IFKE+DEE +R L + + E QT+ +N K K+ K ++ + ++ KRKR+ G D N+V+R+V E+MEK KENFFVIRLH Q+ +LPPI DPD L +S+LM+ R L AREKHLEFSSLRRAK+STL YELH E + ++Y CN C+ Q+E + CKQC +++LCP CY TE HPH + K+ L+ N Q S D+ R ++ R+ K+L H+C CRD NCR+ C MK ++HF+ S ++ C +C+ +C H+K C + KC VP C L+ KQQ QQR++Q QMLRRR+A MQR H TP P+ Q SQ+S + + P SI
Sbjct: 3 GVNMQSSTTDQITYTTDR-PQGLSTEAKMILMRQQLALLLHADHCERLERRGMATNCMDRNCGEIRSLLPHLQSCTREKECSVPHCISSKYIMRHYRSCRDMECKVCSAVRKPIVNSTPSSASSVSCSQNGLSSSHKSDLSSLNGIKISDSPLPPLKTPFTAGSCESQSTVVLNGEVSRVPLHASRITDQQRELAMKKFVNDISLSIFPTANPTAYSDPRMKQFLDYVKRMEKDVFIKSKSTEEYFKTMALHYHNIHSELKEKRRLRESCPPLQNGDISDVTQPSDLTNSVSSENKFKTNPYEQDQF--------SDALEIVCKREEQIQREI----------KVAVENSSNSSESAEVLEDKDGKDDSNSPEVKCHSVASIDPNESDTKTGIEKNDLESEAPEASSSDEKKTDPQTSREPIR-----RRIWYSNELLQYFLPVVLKISKEKDAEPFLTPVDWKFLEIYDYPQIVSDPMDLSTIRKKLEDREYKDPWEIVDDFWLMLNNAWLYNKKTSKVYKTCTRLAETFESIIDPVMQSLGFCCGREYYYQPPTLTCLTPKFCTIYRDAVYYVY---KSDGQ--TPGLLEQKYTVCERCYNEAMDQIALDSDSSN--PVNVQKNLMEKCKNDIKEKEPFVFCKHCGRKWHRVCAIYLEEIWPDGFICNHCIVNYGLKRVENRFTAKKLTTCKLSNFLEKRVNDFLKKKEADAGDVIIRVLAAADKTVEVKSGMKARFCGNGEMPESFPYRVKAIFAFQEIDGQEVCFFGLHVQEYGSECPLPNTRRVYVAYLDSVYFFRPKQFRTEIYHELLVGYIHYAKLLGFTMAHIWACPPSEGDDYIFHMHPPDQKIPKPKRLQEWYQKMLKKALIERIVVDYKDICQDANESHMISPAELAYFEGDFWPNTLEEIFKEMDEEDAKRKQEQEALARGGGDDDDEAKENVQTKEADENPGKKKAKRRKLKRSASI-TITGKRKRLGGIGSGDVANEVARRVYEIMEKHKENFFVIRLHPQNSVTSLPPIKDPDPLINSELMECRGAFLEKAREKHLEFSSLRRAKYSTLVMLYELHNENRQPLMYTCNVCSAQLETPWHCKQCIEYDLCPRCYETENHPHPMVKIGIG-----LDDCNKGQEPSNDSAIQESGRDKLSRWVKALGHSCYCRDANCRVYACKTMKYQVQHFRVHSTDRNQCSVCRFIYYLCCYHSKTCHELKCLVPLCPKLKAKMKQQQKQQRLKQTQMLRRRMATMQRCNSMTPNHQPTPPPSQTYQQCSQSSTSDCISSPMSI 1254
BLAST of CREB-binding protein vs. TrEMBL
Match: A0A419Q0G1 (Histone acetyltransferase OS=Clonorchis sinensis OX=79923 GN=EP300 PE=4 SV=1) HSP 1 Score: 921.768 bits (2381), Expect = 0.000e+0 Identity = 500/1189 (42.05%), Postives = 697/1189 (58.62%), Query Frame = 3
Query: 132 LIRQQLYYLFHASKCTRLAYTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCA-----------PLRPNNNIR-------KSVSNKP---KINGITNYNDQF-------------NNDKEVNWRNTILSI---RPNFLVKLTDELIPVKVCEDVKNHSGYIDVS-----NYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGNMKDNLEFGTI--KKELVANEIPMTPDKEYEQKLAYGSYIKTESWTENDIDSKRELLE-------SSPNAAAKST------PVKLPATQ------------LSTDVKMSPDSTS----TPNKDHTNAHKKWSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMN---SLNNKRKRING---SDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTS-EDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQC-CSIPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNC 3455
L+++QL L HA +C RL C+ +HC++MR V+ H+ KC C HC SSK I++H+ C+ C VC P P + S +KP +NGI N + + N + N RN+ R + + K + + + N + Y D +++K E +IF K+ +Y L ++ ++ L +R + + N +N IK++ A G ++ E + ELV TP +E S D + +++ + S+P+ KS+ P P T+ LS+DVK S + S P ++ +N W EL F+ + I +KD+EPF PV+WE L+I DYP I+ PMDLSTI+ KL N Y +PW VVDDFWLMFNNAWLYNKKTSKVYK C+ LA+ FE+ ID +M GFCCGRE+ YLP L C TP C I RDAVYY ++ND L +Y CE+CYN++ ++++ +++E++ VQK+L+ KC+N+ KE E FVFC+ C RKWH+VCA H D++W +GF C C+R+ +K N Y ++ LP C LS ++E RVN +LK + ++VI+RVL+S+DK VEVKPGMKS +CET +MPESF YR+KA+FAFQEIDGQEVCFFGLHVQEYGS+CP PN+RRVYLAYLDSV+FF P++YRTDVYHE LVGY+ YAK LG+ +AHIWACPP EGDDYIFHMHP +QK+PKPKRLQEWY KML KA+ E +V+DY+DI +A S ++SPTEL YFEGD+WPN LE++FKE+DEE +R + E + ++ + ++ N KK K++ + N SL KRKR+NG +D ++V+R+V E+MEK KENFFVIRLH Q+ ++LP I D D L +SDLM+ R L AREKHLEFSS+RRAK+STL YELH E + ++Y CN CN Q+E + C+QC +++LCP CY TE HPH + ++ + NS S+ + +++ R ++ R K+L H C CRD NCR+ C MK ++HF+ + ++ C +C+ +C+ H+K C + KC VP C
Sbjct: 116 LMQRQLALLLHAERCRRLENDGLTLTCNIRHCMLMRQVLDHMDKCLHEDGCSVAHCRSSKRILRHFNVCSAWSCDVCTAVKRPLIKADIPSHPGTEYQNGPVCNFASSGSKPDTTTMNGIKNPSPHYEVTPTPCSSSPALNGEIGRNNRNSFPLTDEQRKDAMKKFVNVSLSIF---PAANSTAYNDPRMQQFLDHLKRMEKDIFMKSKTAEEYYAALTARYQSIHSELKEQRRLRGARPLEPSNEESN-----------IKND------AHSGRSSESTEPDRVCDGSELVCKREDATPVEEPRSSPVSSSATSFVKSVPMDTVAAQQVNQDCCEPPTSTPSTEIKSSSIDTTQPATAPITRSPRDGDANSDVALSSDVKPSDEPKSEAGQQPLREASN-RAVWYPNELQRYFLPVVDRISKEKDAEPFLQPVDWESLEIYDYPQIITHPMDLSTIRKKLENREYKDPWSVVDDFWLMFNNAWLYNKKTSKVYKTCTKLAEFFETTIDPVMQQLGFCCGREYYYLPPPLTCLTPKFCTIQRDAVYYVYKNDDQT-----PGLLEQKYTVCERCYNEAGDEIR-LDSESS-TVVTVQKNLMEKCKNDRKEKEPFVFCKKCGRKWHRVCAIHADEVWPEGFVCNRCMRDYGLKRPENRYTARKLPTCRLSNFLEKRVNDFLKKKGTDASDVIIRVLASADKTVEVKPGMKSRFCETGDMPESFPYRVKAIFAFQEIDGQEVCFFGLHVQEYGSECPPPNTRRVYLAYLDSVYFFRPKQYRTDVYHEILVGYIHYAKLLGYAVAHIWACPPSEGDDYIFHMHPTDQKIPKPKRLQEWYQKMLKKALLERIVVDYKDICQEACESGLVSPTELAYFEGDFWPNTLEELFKEMDEEDAKRKREQEALARDDEDDETKENLQTRENEKNPGKKKAKKRKMKRNASLSLPGKRKRLNGGNSADASSEVARRVYEIMEKHKENFFVIRLHPQNSVSSLPAIKDLDPLINSDLMECRGAFLERAREKHLEFSSVRRAKYSTLVMLYELHTENRQPLMYTCNMCNVQLETPWHCRQCVEYDLCPRCYETEKHPHPMVQIGLGLDDGTKNSDVDSEAAAVQESGRDKLSRLVKALGHGCSCRDANCRVFACKTMKSNVQHFRVHAAAARNQCNVCRSLSFLCYYHSKTCQELKCPVPLC 1276
BLAST of CREB-binding protein vs. TrEMBL
Match: A0A4Z2D8G9 (CREB-binding protein isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_003439 PE=4 SV=1) HSP 1 Score: 920.998 bits (2379), Expect = 0.000e+0 Identity = 540/1283 (42.09%), Postives = 737/1283 (57.44%), Query Frame = 3
Query: 60 SSEVMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRP-----------------NNNIRKSVSNKPKINGI-----------TNYNDQFNNDKEVNWRNTILSIRPNFLVKLTD---ELIPVKVCEDVK-------NHSGYIDVS-----NYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTK--------QIEKFFQLIKSEFDKFFIAFKGNMKDNLEFGTIKKELVANEIPMTPDKEYEQKLAYGSYIKTESWTE--NDIDSK----------RELLESSPNAAAKSTPVK-------LPATQLSTDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRR------LKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRING---SDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTT-----RARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCSIPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQR-----GMHPETPCPTSVPLQ-SQTSITSINTQPPSI 3638
SS + T Q L K L+RQQL L HA C RL +C +++C +RS++ H+ C K+C HC SSK I++H+++C D+EC+VC+ +R N S+ +NGI T + + N +S P ++TD EL K D+ N + Y D +YVK E ++F K+ + +Y +A + ++ L KR +E+ L + ++ T+ E F+ E D+F D LE ++E + EI K+A + + E D D K + PN + T ++ P S + K P ++ P + + W S EL F+ + I +KD+EPF PV+W+ L+I DYP IV PMDLSTI+ KL + Y +PW++VDDFWLM NNAWLYNKKTSKVYK C+ LA+ FES ID +M S GFCCGRE+ Y P L C TP C I RDAVYY + KS+G+ L +Y CE+CYN++ + + + +N VQK+L+ KC+N++KE E FVFC+ C RKWH+VCA ++++IW DGF C CI +K N + +K L C+LS ++E RVN +LK ++ +VI+RVL+++DK VEVK GMK+ +C EMPESF YR+KA+FAFQEIDGQEVCFFGLHVQEYGS+CP PN+RRVY+AYLDSV+FF P+++RT++YHE LVGY+ YAK LGFTMAHIWACPP EGDDYIFHMHPP+QK+PKPKRLQEWY KML KA+ E +V+DY+DI DA S M+SP EL YFEGD+WPN LE+IFKE+DEE +R L + + E QT+ +N K K+ K ++ + ++ KRKR+ G D N+V+R+V E+MEK KENFFVIRLH Q+ +LPPI DPD L +S+LM+ R L AREKHLEFSSLRRAK+STL YELH E + ++Y CN C+ Q+E + CKQC +++LCP CY TE HPH + K+ L+ N Q S D+ R ++ R+ K+L H+C CRD NCR+ C MK ++HF+ S ++ C +C+ +C H+K C + KC VP C L+ KQQ QQR++Q QMLRRR+A MQR H TP P+ Q SQ+S + + P SI
Sbjct: 3 SSTTDQITYTTDRPQGLSTEAKMILMRQQLALLLHADHCERLERRGMATNCMDRNCGEIRSLLPHLQSCTREKECSVPHCISSKYIMRHYRSCRDMECKVCSAVRKPIVNSTPSSASSVSCSQNGLSSSHKSDLSSLNGIKISDSPLPPLKTPFTAGSCESQSTVVLNGEVSRVPLHASRITDQQRELAMKKFVNDISLSIFPTANPTAYSDPRMKQFLDYVKRMEKDVFIKSKSTEEYFKTMALHYHNIHSELKEKRRLRESCPPLQNGDISDVTQPSDLTNSVSSENKFKTNPYEQDQF--------SDALEIVCKREEQIQREI----------KVAVENSSNSSESAEVLEDKDGKDDSNSPEVKCHSVASIDPNESDTKTGIEKNDLESEAPEASSSDEKKTDPQTSREPIR-----RRIWYSNELLQYFLPVVLKISKEKDAEPFLTPVDWKFLEIYDYPQIVSDPMDLSTIRKKLEDREYKDPWEIVDDFWLMLNNAWLYNKKTSKVYKTCTRLAETFESIIDPVMQSLGFCCGREYYYQPPTLTCLTPKFCTIYRDAVYYVY---KSDGQ--TPGLLEQKYTVCERCYNEAMDQIALDSDSSN--PVNVQKNLMEKCKNDIKEKEPFVFCKHCGRKWHRVCAIYLEEIWPDGFICNHCIVNYGLKRVENRFTAKKLTTCKLSNFLEKRVNDFLKKKEADAGDVIIRVLAAADKTVEVKSGMKARFCGNGEMPESFPYRVKAIFAFQEIDGQEVCFFGLHVQEYGSECPLPNTRRVYVAYLDSVYFFRPKQFRTEIYHELLVGYIHYAKLLGFTMAHIWACPPSEGDDYIFHMHPPDQKIPKPKRLQEWYQKMLKKALIERIVVDYKDICQDANESHMISPAELAYFEGDFWPNTLEEIFKEMDEEDAKRKQEQEALARGGGDDDDEAKENVQTKEADENPGKKKAKRRKLKRSASI-TITGKRKRLGGIGSGDVANEVARRVYEIMEKHKENFFVIRLHPQNSVTSLPPIKDPDPLINSELMECRGAFLEKAREKHLEFSSLRRAKYSTLVMLYELHNENRQPLMYTCNVCSAQLETPWHCKQCIEYDLCPRCYETENHPHPMVKIGIG-----LDDCNKGQEPSNDSAIQESGRDKLSRWVKALGHSCYCRDANCRVYACKTMKYQVQHFRVHSTDRNQCSVCRFIYYLCCYHSKTCHELKCLVPLCPKLKAKMKQQQKQQRLKQTQMLRRRMATMQRCNSMTPNHQPTPPPSQTYQQCSQSSTSDCISSPMSI 1249
BLAST of CREB-binding protein vs. TrEMBL
Match: A0A074YW50 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_12104 PE=4 SV=1) HSP 1 Score: 918.687 bits (2373), Expect = 0.000e+0 Identity = 498/1189 (41.88%), Postives = 700/1189 (58.87%), Query Frame = 3
Query: 132 LIRQQLYYLFHASKCTRLAYTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCA-----------PLRPNNNIRK-------SVSNKP---KINGITNYNDQF-------------NNDKEVNWRNTILSI---RPNFLVKLTDELIPVKVCEDVKNHSGYIDVS-----NYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGNMKDNLEFGTI--KKELVANEIPMTPDKEYEQKLAYGSYIK-TESWTENDIDSKR------ELLESSPNAAAKSTPVKLPA------------------TQLSTDVKMS----PDSTSTPNKDHTNAHKKWSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMN---SLNNKRKRING---SDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTS-EDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQC-CSIPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNC 3455
L+++QL L HA +C RL C+ +HC++MR V+ H+ KC C HC SSK I++H+ C+ C VC P P + S +KP +NGI N + + N + N RN+ R + + K + + + N + Y D +++K E +IF K+ +Y L ++ ++ L +R + + N +N IKSE A G ++ E + E+V TP +E A S +S + + + S++ E ++P+A KS+ + +S+DVK S D+ P ++ +N W EL F+ + I +KD+EPF PV+WE L+I DYP I+ PMDLSTI+ KL N Y +PW VVDDFWLMFNNAWLYNKKTSKVYK C+ LA+ FE+ ID +M GFCCGRE+ YLP L C TP C I RDAVYY ++ND L +Y CE+CYN++ ++++ +++E++ VQK+L+ KC+N+ KE E FVFC+ C RKWH+VCA H D++W +GF C C+R+ +K N Y ++ LP C LS ++E RVN +LK + ++VI+RVL+S+DK VEVKPGMKS +CET +MPESF YR+KA+FAFQEIDGQEVCFFGLHVQEYGS+CP PN+RRVYLAYLDSV+FF P++YRTDVYHE LVGY+ YAK LG+ +AHIWACPP EGDDYIFHMHP +QK+PKPKRLQEWY KML KA+ E +V+DY+DI +A S ++SPTEL YFEGD+WPN LE++FKE+DEE +R + + + ++ + ++ N KK K++ + N SL+ KRKR+NG +D ++V+R+V E+MEK KENFFVIRLH Q+ ++LP I D D L +SDLM+ R L AREKHLEFSS+RRAK+STL YELH E + ++Y CN CN Q+E + C+QC +++LCP CY TE HPH + ++ + +S S+ + +++ R ++ R K+L H C CRD NCR+ C MK ++HF+ + ++ C +C+ +C+ H+K C + KC VP C
Sbjct: 5 LMQRQLALLLHAERCRRLENDGLTLTCNIRHCMLMRQVLDHMDKCLHEDGCSVAHCRSSKRILRHFNVCSAWSCDVCTAVKRPLIKADMPSHPGTEYQNGPVCNFVSSGSKPDTTTVNGIKNPSPHYEVTPTPCSSSPALNGEIGRNNRNSFPLTDEQRKDAMKKFVNVSLSIF---PAANSTAYNDPRMQQFLDHLKRMEKDIFMKSKTAEEYYAALTARYQSIHSELKEQRRLRGARPLEPSNEESN-----------IKSE------AHSGRSSESTEPDRVCDGSEVVCKREDATPVEESRSSPASSSATSFVKSVSMDTVASQQVNQDCCEPPTNTPSAEIKSSSIDTTQPATAPTTRSPRDGDVNSDVTMSSDVKPSDELKSDAGQQPLREASN-RAVWYPNELQRYFLPVVDRISKEKDAEPFLQPVDWESLEIYDYPQIITHPMDLSTIRKKLENREYKDPWSVVDDFWLMFNNAWLYNKKTSKVYKTCTKLAEFFETTIDPVMQQLGFCCGREYYYLPPPLTCLTPKFCTIQRDAVYYVYKNDDQT-----PGLLEQKYTVCERCYNEAGDEIR-LDSESS-TVVTVQKNLMEKCKNDRKEKEPFVFCKKCGRKWHRVCAIHADEVWPEGFVCNRCMRDYGLKRPENRYTARKLPTCRLSNFLEKRVNDFLKKKGTDASDVIIRVLASADKTVEVKPGMKSRFCETGDMPESFPYRVKAIFAFQEIDGQEVCFFGLHVQEYGSECPPPNTRRVYLAYLDSVYFFRPKQYRTDVYHEILVGYIHYAKLLGYAVAHIWACPPSEGDDYIFHMHPTDQKIPKPKRLQEWYQKMLKKALLERIVVDYKDICQEACESGLVSPTELAYFEGDFWPNTLEELFKEMDEEDAKRKREQEALARDDDDDETKENLQTRENEKNPGKKKAKKRKMKRNASLSLSGKRKRLNGGNSADASSEVARRVYEIMEKHKENFFVIRLHPQNSVSSLPAIKDLDPLINSDLMECRGAFLERAREKHLEFSSVRRAKYSTLVMLYELHTENRQPLMYTCNVCNVQLETPWHCRQCVEYDLCPRCYETEKHPHPMVQIGLGLDDGTKHSDVDSEAAAVQESGRDKLSRLVKALGHGCSCRDANCRVFACKTMKSNVQHFRVHAAAARNQCNVCRSLSFLCYYHSKTCQELKCPVPLC 1165
BLAST of CREB-binding protein vs. Ensembl Cavefish
Match: ep300a (histone acetyltransferase p300-like [Source:NCBI gene;Acc:103044365]) HSP 1 Score: 747.273 bits (1928), Expect = 0.000e+0 Identity = 394/836 (47.13%), Postives = 523/836 (62.56%), Query Frame = 3
Query: 972 DSKRELLESSPNAAAKSTP-VKLPATQLSTDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCL 3458
+SK ++E+S A P VK + + + TP+K K + EEL M + L D +S PF+ PV+ LL IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR+ + PQ L C +C I RDA Y+++QN L DRY CEKC+N+ + + + + + K K +N+ + E FV C C RK H++C H + IW GF C C+++ + K N Y +K LP +L Y+ENRVN Y+K ++ P EV +RV+ SDKVVEVKPGMK+ + +T EM ESF YR KA+FAF++IDG +VCFFG+HVQEYGSDCP PN RRVY++YLDSVHFF PR RT VYHE L+GYLEYAKKLGFT HIWACPP EGDDYIFH HP +Q++PKPKRLQEWY KMLDKA+ E +V DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + T +S++ +K + KK K+ K +SL+ K+ G + ND+S+K+ MEK KE FFVIRL + ++ LPPI DPD L DLMDGRD L LAR+KHLEFSSLRR+++S++C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+ H H + K + D+ESN + ++ P D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL
Sbjct: 1016 ESKSTVMETSTAAGEDKKPEVKTEPKEEDAGAGSAGSKSETPSKK-----KIFKPEELRQALMPTLESLYRQDPESLPFRQPVDPSLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDAAYFSYQNSSPK-----YGLLADRYHFCEKCFNEIQGESVSLGDDPSQPQTSITKEQFEKKKNDTLDPELFVECLDCGRKMHQICVLHHETIWPSGFVCNGCLKKANKTRKENKYAAKRLPPTKLGIYLENRVNDYVKRQNHPEAGEVTIRVVHVSDKVVEVKPGMKARFVDTGEMAESFPYRSKALFAFEDIDGADVCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFQPRCMRTTVYHEILIGYLEYAKKLGFTTGHIWACPPSEGDDYIFHCHPTDQRIPKPKRLQEWYKKMLDKAVAERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENNT-------SSESVDATKGDSKNAKKKNNKKTSKNKSSLSRANKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLSAGPNSNALPPIIDPDPLMACDLMDGRDAFLTLARDKHLEFSSLRRSRWSSMCMLVELHNQSQDRFVYTCNECKHHVETRFHCTVCEDYDLCITCYNTKGHEHKMDKLGLGLDDESNNQAAASMQSPG--DSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1832 HSP 2 Score: 83.5741 bits (205), Expect = 2.293e-15 Identity = 44/91 (48.35%), Postives = 58/91 (63.74%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 336 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 426
BLAST of CREB-binding protein vs. Ensembl Cavefish
Match: ep300b (E1A binding protein p300 [Source:NCBI gene;Acc:103032522]) HSP 1 Score: 742.265 bits (1915), Expect = 0.000e+0 Identity = 397/837 (47.43%), Postives = 522/837 (62.37%), Query Frame = 3
Query: 1083 TSTPNKDHTNAHKK-WSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIP-----------DYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDR-DPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQR 3548
+STP+ T + KK + EE+ M + L D +S PF+ PV+ +LL IP DY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M + G+CCGR+ + PQ L C +C I RDA Y+++QN L +RY CEKC+N+ + + + + K K RN+ + E FV C C RK H++C H + IW GF C C+++ + K N Y +K LP +L ++E RVN YLK + P EV +RV+ SDK+VEVKPGMKS + ++ EM ESF YR KA+FAF++IDG +VCFFG+HVQEYGSDCP PN RRVY++YLDSVHFF PR+ RT VYHE L+GY+EY KKLGFT HIWACPP EGDDYIFH HP EQK+PKPKRLQEWY KMLDKA+ E +V DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + T +S+ + + + + + K L R N +K+ + ND+S+K+ MEK KE FFVIRL + A +LPPI DPD L DLMDGRD L LAR+KHLEFSSLRRAK+S++C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+ H H + K+ + N + D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQMLRRRVA MQR
Sbjct: 1025 SSTPS---TQSKKKIFKPEEVRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPVRIRTSNKTNLDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQTLGYCCGRKLEFSPQTLCCYGKQLCTIPRDAAYFSYQNSSPK-----YGLLANRYHFCEKCFNEIQGENVSLGDDPTQPQTSINKDQFQKKRNDTLDPELFVECNDCCRKMHQICVLHNETIWPSGFVCDGCLKKANKTRKENKYAAKRLPQTKLGCFLETRVNDYLKRQAHPESGEVTIRVVHVSDKMVEVKPGMKSRFVDSGEMAESFPYRTKAMFAFEDIDGVDVCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFQPRQLRTGVYHEILIGYIEYVKKLGFTTGHIWACPPSEGDDYIFHCHPLEQKIPKPKRLQEWYKKMLDKAVAERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENST-SSESVDATTGDSKNAKKKNNKKTSKNKSSLSRAN-----KKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPTANSLPPIVDPDPLMACDLMDGRDAFLTLARDKHLEFSSLRRAKWSSMCMLVELHNQSQDRFVYTCNECKHHVETRFHCTVCEDYDLCITCYNTKGHEHKMEKLGLGLDDESSNQAAAATQNPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQLQHRLQQAQMLRRRVATMQR 1847 HSP 2 Score: 83.1889 bits (204), Expect = 2.780e-15 Identity = 44/91 (48.35%), Postives = 58/91 (63.74%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 295 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 385
BLAST of CREB-binding protein vs. Ensembl Cavefish
Match: crebbpa (CREB binding protein a [Source:ZFIN;Acc:ZDB-GENE-050208-439]) HSP 1 Score: 736.487 bits (1900), Expect = 0.000e+0 Identity = 410/913 (44.91%), Postives = 545/913 (59.69%), Query Frame = 3
Query: 867 ELVANEIPMTPDKEYEQKLAYGSYIKTESWTENDIDSKRELLESSPNAAAKSTPVKLPATQLSTDVKMSPDSTSTPNKDHTNA-------HKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYS----ETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQ-RGM 3554
EL A P K+ EQ S ++ E E + +SK L++ A + + + T+VK P + T + K + EEL M + L D +S PF+ PV+ LL IPDY IVK P+DLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M G+CCGR++ + PQ L C +C I RD YY++QN RY CEKC+N+ D + + + K + +N+ + E FV C+ C RK H++C H + IW GF C C+++ K N + +K L L YIE+RVNKYLK ++ P EV VRV++SSDK VEVKPGMK+ + +T EM ESF YR KA+FAF+EIDG +VCFFG+HVQEYGS+CP PN+RRVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S EL YFEGD+WPN LE+ KE+++E R K + ETP G++ + + + K + R N +K+ + ND+S+K+ MEK KE FFVI LHS LPPI DPD L DLMDGRD L LAR+KH EFSSLRR K+ST+C ELH + ++ +Y CN C +E R+ C CEDF+LC +CY T+ H H + K + D++S+ + + P +++ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQM+RRR+A MQ RGM
Sbjct: 672 ELTAAAEPKPEPKQEEQDFE-SSTVEPEPKMETEEESKSLLVKKEEPEATEPKQEPMETEEKKTEVKAEPKEEEEGGANSTTSSSPTQSRRKIFKPEELRQALMPTLESLYRQDPESLPFRQPVDPILLGIPDYFDIVKNPIDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQGLGYCCGRKYEFSPQTLCCYGKQLCTIPRDGTYYSYQN---------------RYHFCEKCFNEIQGDSVTLGDDPAQPQTMISKDQFERKKNDTLDPEPFVECKDCGRKMHQICVLHYEVIWPAGFICDNCLKKSVKSRKENKFSAKRLQSTRLGTYIEDRVNKYLKRQNHPEAGEVFVRVVASSDKTVEVKPGMKARFVDTGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSECPFPNTRRVYISYLDSIHFFKPRMLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPADQKIPKPKRLQEWYRKMLDKAFAERILHDYKDIFKQATEDRLTSANELSYFEGDFWPNVLEESIKELEQEEEERKKEENTAACETPEGTPGDSKNGKKKNNKKTN-----KNKSSVSRAN-----KKKPGMPNVANDLSQKLYATMEKHKEVFFVIHLHSGPMVNTLPPIMDPDPLLTCDLMDGRDAFLTLARDKHWEFSSLRRCKWSTMCMLVELHNQGQDRFVYTCNECKHHVETRWHCTVCEDFDLCINCYNTKGHEHQMVKWGLGLDDDSSGQSGEASKSP--QESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQLQHRLQQAQMMRRRMATMQVRGM 1556 HSP 2 Score: 82.8037 bits (203), Expect = 3.594e-15 Identity = 46/103 (44.66%), Postives = 60/103 (58.25%), Query Frame = 3
Query: 69 VMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
V V + P D +KR LI+QQL L HA KC R G+ C HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 69 VGMVGGQGVSAGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACALPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 171
BLAST of CREB-binding protein vs. Ensembl Cavefish
Match: crebbpa (CREB binding protein a [Source:ZFIN;Acc:ZDB-GENE-050208-439]) HSP 1 Score: 735.717 bits (1898), Expect = 0.000e+0 Identity = 410/913 (44.91%), Postives = 545/913 (59.69%), Query Frame = 3
Query: 867 ELVANEIPMTPDKEYEQKLAYGSYIKTESWTENDIDSKRELLESSPNAAAKSTPVKLPATQLSTDVKMSPDSTSTPNKDHTNA-------HKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYS----ETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQ-RGM 3554
EL A P K+ EQ S ++ E E + +SK L++ A + + + T+VK P + T + K + EEL M + L D +S PF+ PV+ LL IPDY IVK P+DLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M G+CCGR++ + PQ L C +C I RD YY++QN RY CEKC+N+ D + + + K + +N+ + E FV C+ C RK H++C H + IW GF C C+++ K N + +K L L YIE+RVNKYLK ++ P EV VRV++SSDK VEVKPGMK+ + +T EM ESF YR KA+FAF+EIDG +VCFFG+HVQEYGS+CP PN+RRVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S EL YFEGD+WPN LE+ KE+++E R K + ETP G++ + + + K + R N +K+ + ND+S+K+ MEK KE FFVI LHS LPPI DPD L DLMDGRD L LAR+KH EFSSLRR K+ST+C ELH + ++ +Y CN C +E R+ C CEDF+LC +CY T+ H H + K + D++S+ + + P +++ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQM+RRR+A MQ RGM
Sbjct: 651 ELTAAAEPKPEPKQEEQDFE-SSTVEPEPKMETEEESKSLLVKKEEPEATEPKQEPMETEEKKTEVKAEPKEEEEGGANSTTSSSPTQSRRKIFKPEELRQALMPTLESLYRQDPESLPFRQPVDPILLGIPDYFDIVKNPIDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQGLGYCCGRKYEFSPQTLCCYGKQLCTIPRDGTYYSYQN---------------RYHFCEKCFNEIQGDSVTLGDDPAQPQTMISKDQFERKKNDTLDPEPFVECKDCGRKMHQICVLHYEVIWPAGFICDNCLKKSVKSRKENKFSAKRLQSTRLGTYIEDRVNKYLKRQNHPEAGEVFVRVVASSDKTVEVKPGMKARFVDTGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSECPFPNTRRVYISYLDSIHFFKPRMLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPADQKIPKPKRLQEWYRKMLDKAFAERILHDYKDIFKQATEDRLTSANELSYFEGDFWPNVLEESIKELEQEEEERKKEENTAACETPEGTPGDSKNGKKKNNKKTN-----KNKSSVSRAN-----KKKPGMPNVANDLSQKLYATMEKHKEVFFVIHLHSGPMVNTLPPIMDPDPLLTCDLMDGRDAFLTLARDKHWEFSSLRRCKWSTMCMLVELHNQGQDRFVYTCNECKHHVETRWHCTVCEDFDLCINCYNTKGHEHQMVKWGLGLDDDSSGQSGEASKSP--QESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQLQHRLQQAQMMRRRMATMQVRGM 1535 HSP 2 Score: 82.4185 bits (202), Expect = 3.969e-15 Identity = 46/103 (44.66%), Postives = 60/103 (58.25%), Query Frame = 3
Query: 69 VMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
V V + P D +KR LI+QQL L HA KC R G+ C HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 69 VGMVGGQGVSAGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACALPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 171
BLAST of CREB-binding protein vs. Ensembl Cavefish
Match: ENSAMXT00000057848.1 (pep primary_assembly:Astyanax_mexicanus-2.0:12:831065:839047:1 gene:ENSAMXG00000012049.2 transcript:ENSAMXT00000057848.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 79.7221 bits (195), Expect = 4.061e-15 Identity = 48/147 (32.65%), Postives = 76/147 (51.70%), Query Frame = 3
Query: 1005 NAAAKSTPVKLPATQLSTDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDI 1445
AA + P+++ + +T + +P T N HT H + +L L + + + + S PF+ PV+ L +PDY I+KCPMD+ TIK +L N Y N + + DF MF N ++YNK + M L K+F KI ++
Sbjct: 10 RAAPRYQPIRMGDSVEATPLSKNPLVPETTN--HT--HPARMTNQLQYLLKVVLKTLWKHQFSWPFQAPVDAVKLRLPDYYKIIKCPMDMGTIKKRLENRYYRNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKMFLQKISEM 152
BLAST of CREB-binding protein vs. Ensembl Sea Lamprey
Match: ep300a (E1A binding protein p300 a [Source:ZFIN;Acc:ZDB-GENE-080403-16]) HSP 1 Score: 568.54 bits (1464), Expect = 6.977e-178 Identity = 321/709 (45.28%), Postives = 433/709 (61.07%), Query Frame = 3
Query: 1698 VQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSK----GLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALED-IFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALM-------------QRGMHPETPCPTSVPLQSQTSITSINTQPPSI----------DAPTATILPEKISEPNESDTCKRNNIVMQ 3725
+ K K +N+ + E FV C+ C RK H++CA H + IW GF C TC+++ K N + SK GLP +L ++ENRVN +L+ ++ P EV VRV+ SDK VEVKPGMK+ + + EM +SF YR KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN RRVY++YLDSVHFF PR RT VYHE L+GYLEY KK+G+T HIWACPP EGDDYIFH HPP+Q++PKPKRLQEWY KMLDKA+ E +V DY+DI A + + S ELPYFEGD+WPN LE+ I + EE R+ + S + S EG+ K + KK K+ K +S + K+ G ++ ND+S+K+ MEK KE FFVIRLH + A ++PPI DPD L DLMDGRD L +AR+KH EFSSLRRAK+ST+C ELH + ++ +Y CN C +E RY C CED++LC +CY T+ H H + K + D++SN QN +++ R + R +SL HACQC + NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQMLRRR+A M H P PT S +S+ + T P ++ P + ++P +S+P + T N + Q
Sbjct: 2 INKDQFEKKKNDTLDPEPFVECKECGRKLHQICALHNETIWPAGFVCDTCLKKTGRTRKENKFCSKSLNAGLPTSKLGTHLENRVNNFLRRQNCPEAGEVTVRVVHVSDKTVEVKPGMKARFVDNGEMADSFPYRAKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPRHLRTAVYHEILIGYLEYVKKIGYTQGHIWACPPSEGDDYIFHCHPPDQRIPKPKRLQEWYKKMLDKAVAERIVHDYKDILKQATDDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREETSASCESTEGK--------KGDSKNAKKKNNKKTSKSKSSSSRTSKKKPGMPSVSNDLSQKLYATMEKHKEVFFVIRLHPPAAANSVPPIQDPDPLVTCDLMDGRDAFLTMARDKHYEFSSLRRAKWSTMCMLVELHNQGQDRFVYTCNECKHHVETRYHCTVCEDYDLCVACYKTKGHEHKMEKWGLGLDDDSNNQPMQN-----PQESRRLSIQRCIQSLVHACQCLNANCSLPSCLKMKRVVQHTRVCKRKTNGGCPICKQLIALCCFHAKHCQENKCPVPFCLNIKHKLRQQQLQHRLQQAQMLRRRMAAMTQVTQQQPPPPPRVTPPHAGLPSPTGT---SGSSVPTTPTGPQAVPQTPPGPTVGQPPQSALVPPGLSQPPNNVTLANNGMARQ 694
BLAST of CREB-binding protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006336.1 (pep scaffold:Pmarinus_7.0:GL479543:3524:30791:1 gene:ENSPMAG00000005717.1 transcript:ENSPMAT00000006336.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 176.792 bits (447), Expect = 4.678e-45 Identity = 82/160 (51.25%), Postives = 103/160 (64.38%), Query Frame = 3
Query: 1089 TPNKDHTNAHKKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQN 1565
+P K + EEL M + L D +S PF+ PV+ + L IPDY IVK PMDLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S G+CCGR++ + PQ L C +C I RDA Y+++QN
Sbjct: 781 SPATPQPRPKKVFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQALGIPDYFDIVKTPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDASYFSYQN 940 HSP 2 Score: 79.337 bits (194), Expect = 5.215e-15 Identity = 44/92 (47.83%), Postives = 58/92 (63.04%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCK-FQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 69 PAADPEKRKLIQQQLVLLLHAHKCQRREQGNGEVRPCNLPHCRTMKNVLNHMTHCQAGKSCQAVAHCASSRQIISHWKNCTRPDCPVCLPLK 160
BLAST of CREB-binding protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006283.1 (pep scaffold:Pmarinus_7.0:GL487345:511:5582:1 gene:ENSPMAG00000005678.1 transcript:ENSPMAT00000006283.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 75.0998 bits (183), Expect = 1.104e-14 Identity = 43/122 (35.25%), Postives = 68/122 (55.74%), Query Frame = 3
Query: 1095 NKDHTNAHKKWSSEELSDLFMEIHQL---ILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNK-KTSKVYKMCSTLAKLFESKIDDIM 1448
K T +++ S+ ++ + QL IL +DSEPF+ PV+ + PDY +I+ PMDL T++++L Y++P D D L+F+NA Y K S++Y M L+ LFE I I+
Sbjct: 128 QKRRTQRYRRESAYNIAAWKQQCRQLVSVILEREDSEPFRQPVD--PIAYPDYRTIIPTPMDLGTVRERLREDTYHDPVDFCKDVRLIFSNAKAYTPNKKSRIYGMTLRLSALFEEHIRGIV 247
BLAST of CREB-binding protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002730.1 (pep scaffold:Pmarinus_7.0:GL482934:3:7765:-1 gene:ENSPMAG00000002495.1 transcript:ENSPMAT00000002730.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 71.633 bits (174), Expect = 5.438e-13 Identity = 34/80 (42.50%), Postives = 48/80 (60.00%), Query Frame = 3
Query: 1197 PFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKI 1436
PF +PV+ L +PDY I+K PMD+ TI+ +L N Y + + + DF MF N +LYNK T + M TL +LF K+
Sbjct: 85 PFNVPVDANALHLPDYHKIIKQPMDMGTIRRRLENNYYWSGGECIQDFNTMFTNCYLYNKPTDDIVLMAQTLERLFLQKV 164 HSP 2 Score: 60.8474 bits (146), Expect = 1.485e-9 Identity = 48/150 (32.00%), Postives = 70/150 (46.67%), Query Frame = 3
Query: 1011 AAKSTPVKLPATQLSTDVKMSPDSTSTPN--KDHTNAHKKWSSEELS-------DLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESK 1433
AA S K+PA + S + P P+ + H + K SE+L +LF + H + PF PV+ L + DY I+K PMDLSTIK+K+ N Y + + D +MF+N + YN V M L +FE +
Sbjct: 289 AADSKAAKIPARRESGR-PIKPPRKDLPDSQQQHQTSKKVKLSEQLKHCNGILKELFAKKHAAY-----AWPFYKPVDASTLGLHDYHDIIKHPMDLSTIKNKMDNRDYRDAQEFAADVRVMFSNCYKYNPPDHDVVSMARKLQDVFEMR 432
BLAST of CREB-binding protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002732.1 (pep scaffold:Pmarinus_7.0:GL482934:3:7597:-1 gene:ENSPMAG00000002495.1 transcript:ENSPMAT00000002732.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 70.4774 bits (171), Expect = 1.393e-12 Identity = 34/80 (42.50%), Postives = 48/80 (60.00%), Query Frame = 3
Query: 1197 PFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKI 1436
PF +PV+ L +PDY I+K PMD+ TI+ +L N Y + + + DF MF N +LYNK T + M TL +LF K+
Sbjct: 54 PFNVPVDANALHLPDYHKIIKQPMDMGTIRRRLENNYYWSGGECIQDFNTMFTNCYLYNKPTDDIVLMAQTLERLFLQKV 133 HSP 2 Score: 56.9954 bits (136), Expect = 2.481e-8 Identity = 47/151 (31.13%), Postives = 66/151 (43.71%), Query Frame = 3
Query: 1002 PNAAAKSTPVKLPATQLSTDVKMSPDSTSTPNKDHTNAHKKWSSEELS-------DLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESK 1433
P P+K P L PDS + H + K SE+L +LF + H + PF PV+ L + DY I+K PMDLSTIK+K+ N Y + + D +MF+N + YN V M L +FE +
Sbjct: 280 PARRESGRPIKPPRKDL-------PDS----QQQHQTSKKVKLSEQLKHCNGILKELFAKKHAAY-----AWPFYKPVDASTLGLHDYHDIIKHPMDLSTIKNKMDNRDYRDAQEFAADVRVMFSNCYKYNPPDHDVVSMARKLQDVFEMR 414
BLAST of CREB-binding protein vs. Ensembl Yeast
Match: BDF1 (Protein involved in transcription initiation; functions at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf2p; BDF1 has a paralog, BDF2, that arose from the whole genome duplication [Source:SGD;Acc:S000004391]) HSP 1 Score: 65.855 bits (159), Expect = 4.765e-11 Identity = 34/81 (41.98%), Postives = 47/81 (58.02%), Query Frame = 3
Query: 1185 KDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFE 1427
KD+ PF PV+ LDIP Y + +K PMDLSTI+ KL G Y P + +DF LM NN+ +N + + +M + FE
Sbjct: 168 KDARPFLQPVDPVKLDIPFYFNYIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNNSIKFNGPNAGISQMARNIQASFE 248
BLAST of CREB-binding protein vs. Ensembl Yeast
Match: GCN5 (Catalytic subunit of ADA and SAGA histone acetyltransferase complexes; modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; relocalizes to the cytosol in response to hypoxia; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; greater involvement in repression of RNAPII-dependent transcription than in activation [Source:SGD;Acc:S000003484]) HSP 1 Score: 62.7734 bits (151), Expect = 2.245e-10 Identity = 34/83 (40.96%), Postives = 49/83 (59.04%), Query Frame = 3
Query: 1197 PFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDI 1445
PF PVN E ++PDY +K PMDLST++ KL + Y D + D L+FNN +YN + + YK + L K F +K+ +I
Sbjct: 351 PFLQPVNKE--EVPDYYDFIKEPMDLSTMEIKLESNKYQKMEDFIYDARLVFNNCRMYNGENTSYYKYANRLEKFFNNKVKEI 431
BLAST of CREB-binding protein vs. Ensembl Yeast
Match: BDF2 (Protein involved in transcription initiation; acts at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf1p; protein abundance increases in response to DNA replication stress; BDF2 has a paralog, BDF1, that arose from the whole genome duplication [Source:SGD;Acc:S000002228]) HSP 1 Score: 59.6918 bits (143), Expect = 3.407e-9 Identity = 34/93 (36.56%), Postives = 57/93 (61.29%), Query Frame = 3
Query: 1155 MEIHQLILSDKDSE---PFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLF 1424
++I ++++S K+S+ PF PV+ L++P+Y +VK PMDL TI + L+N Y VDD L+F N + +N + ++V+ M L +LF
Sbjct: 327 LKILKVLMSKKNSDINFPFLQPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGNEVHSMGKKLKELF 419 HSP 2 Score: 58.9214 bits (141), Expect = 5.131e-9 Identity = 32/84 (38.10%), Postives = 46/84 (54.76%), Query Frame = 3
Query: 1185 KDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKI 1436
KD+ PF PV+ L+IP Y + V+ PMDLS I+ KL +Y++ V DF M +N +N S + M + K FE K+
Sbjct: 153 KDARPFLKPVDPIALNIPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPESSISSMAKRIQKYFEKKL 236
BLAST of CREB-binding protein vs. Ensembl Yeast
Match: RSC4 (Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling; acetylated (K25) by Gcn5p, altering replication stress tolerance; contains tandem bromodomains that recognize histone H3 acetylated on K14 (H3K14ac) by Gcn5p [Source:SGD;Acc:S000001716]) HSP 1 Score: 54.6842 bits (130), Expect = 1.093e-7 Identity = 32/83 (38.55%), Postives = 46/83 (55.42%), Query Frame = 3
Query: 1185 KDSEPFKLPVNWELLD---IPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLF 1424
K SEPF EL+D +P+Y IV PM LS +K L G Y+ +D + D L+F NA ++N ++ +YK +TL F
Sbjct: 208 KLSEPF-----MELVDKDELPEYYEIVHSPMALSIVKQNLEIGQYSKIYDFIIDMLLVFQNAHIFNDPSALIYKDATTLTNYF 285
BLAST of CREB-binding protein vs. Ensembl Nematostella
Match: EDO40753 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S640]) HSP 1 Score: 684.871 bits (1766), Expect = 0.000e+0 Identity = 353/782 (45.14%), Postives = 487/782 (62.28%), Query Frame = 3
Query: 1134 EELSDLFM-EIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNS-QEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRING-SDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSL----FKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCSIPKS-TCKMCQLFLRICFVHAKFCSDSKCQVPNC 3455
EEL M + +L + +S PF+ PV+ +LL DY IV+ PMDLSTIK KL NG Y NPW+ DD WLMF+NAWLYN+KTS+VYK C+ L+++FES+ID +M G+CCGR++V+ PQVL C +C I RD YY +QN + + KC+N+ D+ + + + K K +N+ + E FV C C RK H++C H D IW G+ C C+ ++ +K K N Y ++ L H L IE RVN +L+ + EV +RV+SS K E+KPGMK+ Y + ++PE F Y+ KA+FAF+EIDG +VCFFG+HVQEYGSDC PN+RRVY++YLDSVHFF PR+ RT VYHE L+GYLE+ ++GF MAHIWACPP EGDDYIFH HPPEQK+PK KRL +WY KMLDKAI + VVI+Y+DI A + + +P ELPYF+GD+WPNALED +E+D+E R + + S +EG ++V + S K K + R S K+ING S + D+S+++ MEK +E FFVIRL+ + P +DPD + DLMDGRD L LAR+KH EFSS RRA+FST+ ELH + + +Y CN C + +E RY C +CED++LC CY + H H + F +D +++S + +++ R ++ R +SL HA CRD+NC + CAKMK +++H + C S C++CQ + +C HAK C + +C VP C
Sbjct: 668 EELRLALMPTLEKLYKQEPESLPFRSPVDPKLLGCLDYFEIVRNPMDLSTIKRKLDNGQYKNPWEYCDDVWLMFDNAWLYNRKTSRVYKYCTKLSEVFESEIDPVMKLLGYCCGRKYVFHPQVLCCFGKQLCTITRDTAYYTYQNRQE-------------IVTFPKCFNEIQGDMVNLGEDPTLQQSLIPKDQFVKLKNDHLDVEPFVECIDCGRKVHQICVLHHDLIWPTGYQCDACLNKRGVKKKENKYTARRLQHTRLGEKIETRVNTFLQKQG-CPAEVTIRVVSSVQKQAEIKPGMKTRYEGSGQLPEYFPYQAKALFAFEEIDGTDVCFFGMHVQEYGSDCQQPNTRRVYVSYLDSVHFFQPRQLRTAVYHEILIGYLEHVGQIGFQMAHIWACPPSEGDDYIFHCHPPEQKIPKHKRLVDWYKKMLDKAIMDKVVIEYKDILKQASDDGLTNPKELPYFDGDFWPNALEDSIRELDQEEEERKANAAAAEASGKEG----SKVKGNSKRSNSKKGTKSKAGSRKLS-----KKINGPSMELCDLSQRLYSTMEKHREVFFVIRLNGR----KTPDTSDPDPMMTCDLMDGRDAFLTLARDKHYEFSSNRRAQFSTMAMLVELHNQGNDRFVYTCNLCKRPVETRYHCNECEDYDLCVPCYDEKGHEHKMERLGFDLDVEQQSQPSKDGQPQKMNAQEERRLKIQRCIQSLVHATHCRDINCTMLSCAKMKRVVEHTKSCRKKTSGGCRICQELIHLCCYHAKHCMERECVVPFC 1422 HSP 2 Score: 80.4925 bits (197), Expect = 4.952e-15 Identity = 46/105 (43.81%), Postives = 62/105 (59.05%), Query Frame = 3
Query: 111 VDSDKRFLIRQQLYYLFHASKCTRLAYTTGKGD---CHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNIRKSVSNKPK 416
D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T C +GK C+ HC SS++II HWKNC +C VC PL+ ++ R S PK
Sbjct: 1 ADPEKRRLIQQQLVLLLHAHKCQRREQQAANGEMKSCNLPHCRTMKNVLNHMTTCTAGKTCQVAHCASSRQIISHWKNCMRQDCPVCLPLKHASDRRISQGRAPK 105
BLAST of CREB-binding protein vs. Ensembl Nematostella
Match: EDO31845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWS2]) HSP 1 Score: 74.7146 bits (182), Expect = 1.288e-13 Identity = 41/108 (37.96%), Postives = 61/108 (56.48%), Query Frame = 3
Query: 1113 AHKKWSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKI 1436
A K ++ +L L + + + + PF+ PV+ L++PDY +I+K PMDL TIK KL N Y + ++DF LM NN + YNK + MC ++ KLF KI
Sbjct: 10 APKTRTTNQLQFLLKTVLKGLWRHHHAWPFREPVDAVKLNLPDYHTIIKKPMDLGTIKKKLENNEYPCAQECIEDFRLMINNCYTYNKPGDDIVLMCQSMDKLFHQKI 117 HSP 2 Score: 71.633 bits (174), Expect = 1.206e-12 Identity = 51/145 (35.17%), Postives = 70/145 (48.28%), Query Frame = 3
Query: 1020 STPVKLPATQLSTDVKMSPD-------STSTPNKDHTNAHKKWSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESK 1433
S P K+PA + ST P+ S S K K+ S L D+F + H + PF PV+ E L + DY I+K PMD++ IK+KL N Y++P + D LMF+N + YN V KM L +FE K
Sbjct: 247 SKPAKVPARRESTRTVKKPNRDLPEGPSLSRGKKKPLTEQLKYCSTILKDMFSKKHYAY-----AWPFYKPVDAEALGLHDYHDIIKQPMDMTEIKNKLENRAYDSPSEFAADIRLMFSNCYRYNPPDHDVVKMARQLQDVFEMK 386
BLAST of CREB-binding protein vs. Ensembl Nematostella
Match: EDO38859 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBV1]) HSP 1 Score: 75.485 bits (184), Expect = 1.798e-13 Identity = 39/94 (41.49%), Postives = 57/94 (60.64%), Query Frame = 3
Query: 1170 LILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKT-SKVYKMCSTLAKLFESKIDDIM 1448
++S +D+EPF PVN L D PDY V+ PMD ST+ K V Y++P +V D L+F+N+ YN + S++Y M LA +FE ++D I
Sbjct: 1301 FLMSREDAEPFLAPVN--LADFPDYTDYVEQPMDFSTVWRKFVENQYSDPEQLVSDIRLVFSNSRAYNTQPRSRIYSMTIRLAAMFEDRVDSIF 1392
BLAST of CREB-binding protein vs. Ensembl Nematostella
Match: EDO44814 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUU7]) HSP 1 Score: 56.9954 bits (136), Expect = 2.718e-8 Identity = 39/132 (29.55%), Postives = 68/132 (51.52%), Query Frame = 3
Query: 1059 DVKMSPDSTSTPNKDHTNAH---KKWSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDI 1445
D +MS D + H +K S++++ + ++ D D+ PF +PVN + P+Y I++ PMD T+K KL + Y++P + D L+F N +N+ S+V + L+K FES+ D+
Sbjct: 185 DFEMSQDGEDEEGDNQETRHHINRKQQSKDMAPCRTILAEMEKHD-DAWPFLIPVNAK--QFPEYYKIIRKPMDFHTMKIKLRDYQYSSPQEFAQDSRLVFANCEEFNEDDSEVGQAGKRLSKFFESRWSDL 313
BLAST of CREB-binding protein vs. Ensembl Nematostella
Match: EDO44902 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUH0]) HSP 1 Score: 52.373 bits (124), Expect = 1.169e-7 Identity = 30/88 (34.09%), Postives = 47/88 (53.41%), Query Frame = 3
Query: 1173 ILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKI 1436
+ S K + PF PV+ LD+P Y ++K PMDLST++DK+ + Y V D +F+N +N K + Y+ L +F K+
Sbjct: 63 LQSHKMAWPFLEPVSG--LDVPGYYDVIKEPMDLSTVEDKITSKKYATLEQFVSDVTRIFDNCRFFNGKDTPYYRCAEVLEAVFVQKL 148
BLAST of CREB-binding protein vs. Ensembl Medaka
Match: ep300b (histone acetyltransferase p300 [Source:NCBI gene;Acc:101168870]) HSP 1 Score: 758.829 bits (1958), Expect = 0.000e+0 Identity = 402/857 (46.91%), Postives = 539/857 (62.89%), Query Frame = 3
Query: 1077 DSTSTPNKDHTNAHKK--WSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDP-TINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHPETPCPTS--VPLQSQTSITSINT 3623
ST+T + T KK + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW ++D WLMFNNAWLYN+KTS+VYK CS LA++FE++ID +M G+CCGR+F + PQ L C +C I RDA Y+++QN L DRY CEKC+N+ + + + + + K + +N+ + E V C C RK H++C H + IW GF C C++ + K N Y +K LP +L ++E RVN YLK ++ EV +RV+ SDKVVEVKPGMKS + ++ EM ESF YR+KA+FAF++IDG +VCFFG+HVQEYGSDCP PN RRVY++YLDSVHFF PR RT VYHE L+GYLEY K+ GFT HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA+ E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + T +S++ +S+ + KK K+ K +SL+ K+ G ++ ND+S+K+ MEK KE FFVIRL + A +LPPI DPD L DLMDGRD L LAR+KHLEFSSLRR+K+S++C ELH + ++ +Y CN C + +E R+ C CED++LC +CY + H H + K+ + + N + D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQMLRRR+A MQR P P V L S ++T+ NT
Sbjct: 1018 GSTTTNSSPATAQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYIEDVWLMFNNAWLYNRKTSRVYKYCSKLAEVFETEIDPVMQGLGYCCGRKFEFSPQTLCCYGKQLCTIQRDAAYFSYQNSSPK-----YGLLADRYHFCEKCFNEIQGESVSLGDDPSQPQTSINKDQFQRKKNDTLDPELLVECIDCGRKMHQICVLHNETIWPSGFVCDNCLKRANKSRKENKYAAKRLPQTKLGNFLETRVNDYLKRQNHLESGEVTIRVVHVSDKVVEVKPGMKSRFVDSGEMSESFPYRMKALFAFEDIDGADVCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFKPRHLRTAVYHEILLGYLEYVKRQGFTAGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENST-------SSESTDVSRGDSKNAKKKNNKKTSKNKSSLSRANKKKPGMPSVSNDLSQKLYATMEKHKEVFFVIRLIAGPTANSLPPITDPDPLMACDLMDGRDAFLTLARDKHLEFSSLRRSKWSSMCMLVELHNQSQDRFVYTCNECKRHVETRFHCTVCEDYDLCITCYNIKGHEHKMDKLGLGLDDDGNNQAAAAAQNPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQHLQHRLQQAQMLRRRMATMQRAGQPAGAMPGGPVVGLPSPGNVTAPNT 1862 HSP 2 Score: 83.1889 bits (204), Expect = 2.794e-15 Identity = 44/91 (48.35%), Postives = 58/91 (63.74%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 311 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 401
BLAST of CREB-binding protein vs. Ensembl Medaka
Match: ep300a (histone acetyltransferase p300 [Source:NCBI gene;Acc:101160197]) HSP 1 Score: 755.747 bits (1950), Expect = 0.000e+0 Identity = 426/931 (45.76%), Postives = 563/931 (60.47%), Query Frame = 3
Query: 939 IKTESWTENDIDSKRELLESSPNAAAKSTPVKL----PATQLSTDVKMSPDSTSTPNKDHTNAHKK-WSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHP-----------ETPCPTSVPLQSQTSITSINTQPPSIDAPTATILP 3665
IK+E E D E + +P A+ ++ VK+ PA ++ + TP T A KK + EEL M + L D +S PF++PV+ +LL IPDY IVK PMDLSTIK KL G Y +PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FE +ID +M S +CCGR+ + PQ L C +C I RD VY+++QN RY CEKC+N+ D + + + K K +N+ + E FV C C R+ H++C H + IW GF C C+++ + K N Y +K LP +L Y+E RVN +LK + P EV +RV+ SDKVVEVKPGMKS + ++ EM ESF YR KA+FAF++IDG +VCFFG+HVQEYGSDCP PN RRVY++YLDSVHFF PR RT VYHE L+GYLEY KKLG+T HIWACPP EGDDYIFH HP +QK+PKPKRLQEWY KMLDKA+ E +V DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + T N +T K + KK K+ K +SL+ K+ G + ND+S+K+ MEK KE FFVIRL + A +LPPI+DPD L DLMDGRD L LAR+KHLEFSSLRRAK+S++C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+ H H + K + D+ES+ + P E + R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQMLRRR+A MQR P +P ++ P + TS TQPP+ P +P
Sbjct: 1047 IKSEFKKE---DCSGEGGKGAPPDASATSAVKMEDRKPAVKVEVKEEEESSDGVTP---QTPAKKKIFKPEELRQSLMPTLESLYRQDPESLPFRMPVDPQLLCIPDYFDIVKNPMDLSTIKRKLDTGQYQDPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQSLSYCCGRKLEFSPQTLCCYGKQLCTIPRDGVYFSYQN---------------RYHFCEKCFNEIQGDSVSLGDDPTQPQASINKDQFEKKKNDTLDPELFVECLDCGRRMHQICVLHNETIWPSGFVCDACLKKSNKSRKENKYSAKRLPQTKLGCYLETRVNDFLKRQSHPESGEVFIRVVHVSDKVVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEDIDGADVCFFGMHVQEYGSDCPQPNQRRVYISYLDSVHFFRPRSLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPMDQKIPKPKRLQEWYKKMLDKAVAERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENSTSNESIDDT-------KGDSKNAKKKNNKKTSKNKSSLSRANKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAAPMANSLPPISDPDPLMACDLMDGRDAFLTLARDKHLEFSSLRRAKWSSMCMLVELHNQSQDRFVYTCNECKHHVETRFHCTVCEDYDLCITCYNTKGHEHKMEKLGLGLDDESSSQAAAATQSP--EYSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQLQHRLQQAQMLRRRMASMQRVGQPPPGAVPGGNGLPSPGGSNGPPTGPATPTSAGTQPPTPQTPGQNNMP 1947 HSP 2 Score: 80.4925 bits (197), Expect = 1.683e-14 Identity = 43/88 (48.86%), Postives = 57/88 (64.77%), Query Frame = 3
Query: 114 DSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 372 DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 459
BLAST of CREB-binding protein vs. Ensembl Medaka
Match: crebbpb (adenylate cyclase 9 [Source:NCBI gene;Acc:101155516]) HSP 1 Score: 754.207 bits (1946), Expect = 0.000e+0 Identity = 417/901 (46.28%), Postives = 556/901 (61.71%), Query Frame = 3
Query: 960 ENDIDSKRELLE-SSPNAA-AKSTPVKL-PATQLSTDVKMSPDSTSTPNKDHTNA---HKK-WSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQ-RGMHPETPCPTSVPLQSQTSITSINT 3623
E D ++K +++ P+AA K P++ PA + T+VK P + T+ HKK + EEL M + L D +S PF+ PV+ LL IPDY IVK P+DLSTIK KL G Y PW V+D WLMFNNAWLYN+KTS+VYK C+ LA++FE +ID +M S G+CCGR++ + PQ L C +C I RD YY++QN L DRY CEKC+N+ + + + + K K +N+ + E FV C+ C RK H++C H + IW GF C C+++ K N + ++ L L YIE+RVNKYLK ++ P EV VRV++SSDK V+VKPGMKS + ++ EM E+F YR KA+FAF+EIDG +VCFFG+HVQEYGSDCP PN+RRVY++YLDSVHFF PR RT VYHE L+GYLEY KKLG+ M HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R K + T +S+ E +Q + + + K L R N +K+ + ND+S+K+ MEK KE FFVI LH+ LPPI DPD L DLMDGRD L LAR+KH EFSSLRR K+ST+C ELH + ++ +Y CN C +E R+ C CED++LC +CY T+ H H + K + D++SN + P ++ R + R +SL HACQCR+ NC ++ C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ QQ Q R+ QAQM+RRR+A M RGM +P PTS L + S+ NT
Sbjct: 967 EQDDETKPSVVKKEEPDAAKPKQEPMEAEPA--IKTEVKTEPKEEEEGGANSTSTSQNHKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPMLLGIPDYFDIVKNPIDLSTIKRKLDTGQYQEPWQYVEDVWLMFNNAWLYNRKTSRVYKYCTKLAEVFEVEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTISRDGTYYSYQNSSPK-----YGLIADRYHFCEKCFNEIQGNSVTLGDDPAQPQTVISKEQFEKKKNDTLDPEPFVECKDCERKMHQICVLHYEVIWPSGFICDNCLKKSGKTKKENKFSARRLQTTRLGTYIEDRVNKYLKRQNHPEAGEVFVRVVASSDKSVDVKPGMKSRFVDSGEMMENFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPFPNTRRVYISYLDSVHFFKPRLLRTAVYHEILIGYLEYVKKLGYVMGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYRKMLDKAFAERILHDYKDIFKQATEDRLTSANELPYFEGDFWPNVLEESIKELEQEEEERKKEEN-TASSETTEGAQADSKNAKKKNNKKTNKNKSSLSRAN-----KKKPGMPNVANDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIMDPDPLLTCDLMDGRDAFLTLARDKHWEFSSLRRCKWSTMCMLVELHNQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYKTKGHEHQMVKWGLGLDDDSNGQGGEASKSP--QENRRLSIQRCIQSLVHACQCRNANCSLSSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKQKLHQQQLQHRLHQAQMMRRRMATMAGRGMPMPSP-PTSTALDTPNSLQQPNT 1851 HSP 2 Score: 82.8037 bits (203), Expect = 3.716e-15 Identity = 44/91 (48.35%), Postives = 57/91 (62.64%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 304 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRSCALPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 394
BLAST of CREB-binding protein vs. Ensembl Medaka
Match: ep300b (histone acetyltransferase p300 [Source:NCBI gene;Acc:101168870]) HSP 1 Score: 751.895 bits (1940), Expect = 0.000e+0 Identity = 401/857 (46.79%), Postives = 536/857 (62.54%), Query Frame = 3
Query: 1077 DSTSTPNKDHTNAHKK--WSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDP-TINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTI-NDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHPETPCPTS--VPLQSQTSITSINT 3623
ST+T + T KK + EEL M + L D +S PF+ PV+ +LL IPDY IVK PMDLSTIK KL G Y PW ++D WLMFNNAWLYN+KTS+VYK CS LA++FE++ID +M G+CCGR+F + PQ L C +C I RDA Y+++QN RY CEKC+N+ + + + + + K + +N+ + E V C C RK H++C H + IW GF C C++ + K N Y +K LP +L ++E RVN YLK ++ EV +RV+ SDKVVEVKPGMKS + ++ EM ESF YR+KA+FAF++IDG +VCFFG+HVQEYGSDCP PN RRVY++YLDSVHFF PR RT VYHE L+GYLEY K+ GFT HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA+ E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R + + T +S++ SK + KK K+ K +SL+ K+ G ++ ND+S+K+ MEK KE FFVIRL + A +LPPI DPD L DLMDGRD L LAR+KHLEFSSLRR+K+S++C ELH + ++ +Y CN C + +E R+ C CED++LC +CY + H H + K+ + + N + D+ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +QQ Q R+QQAQMLRRR+A MQR P P V L S ++T+ NT
Sbjct: 1086 GSTTTNSSPATAQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYIEDVWLMFNNAWLYNRKTSRVYKYCSKLAEVFETEIDPVMQGLGYCCGRKFEFSPQTLCCYGKQLCTIQRDAAYFSYQN---------------RYHFCEKCFNEIQGESVSLGDDPSQPQTSINKDQFQRKKNDTLDPELLVECIDCGRKMHQICVLHNETIWPSGFVCDNCLKRANKSRKENKYAAKRLPQTKLGNFLETRVNDYLKRQNHLESGEVTIRVVHVSDKVVEVKPGMKSRFVDSGEMSESFPYRMKALFAFEDIDGADVCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFKPRHLRTAVYHEILLGYLEYVKRQGFTAGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENST-------SSESTDPSKGDSKNAKKKNNKKTSKNKSSLSRANKKKPGMPSVSNDLSQKLYATMEKHKEVFFVIRLIAGPTANSLPPITDPDPLMACDLMDGRDAFLTLARDKHLEFSSLRRSKWSSMCMLVELHNQSQDRFVYTCNECKRHVETRFHCTVCEDYDLCITCYNIKGHEHKMDKLGLGLDDDGNNQAAAAAQNPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQHLQHRLQQAQMLRRRMATMQRAGQPAGAMPGGPVVGLPSPGNVTAPNT 1920 HSP 2 Score: 83.1889 bits (204), Expect = 2.779e-15 Identity = 44/91 (48.35%), Postives = 58/91 (63.74%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C+ HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 335 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 425
BLAST of CREB-binding protein vs. Ensembl Medaka
Match: crebbpa (CREB-binding protein [Source:NCBI gene;Acc:101163392]) HSP 1 Score: 744.191 bits (1920), Expect = 0.000e+0 Identity = 374/792 (47.22%), Postives = 495/792 (62.50%), Query Frame = 3
Query: 1119 KKWSSEELSDLFME-IHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRD-PTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFK--VDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWK 3479
K + EEL M + L D +S PF+ PV+ LL IPDY IVK P+DLSTIK KL G Y PW VDD WLMFNNAWLYN+KTS+VYK CS LA++FES+ID +M S G+CCGR++ + PQ L C +C I YY++QN RY CEKC+ND D + + + K + +N+V + E FV C+ C RK H++C H + IW GF C C+++ K N + +K L L +IE+RVNKYLK ++ P EV VRV++SSDK VEVKPGMK+ + +T EMPE+F YR KA+FAF+EIDG +VCFFG+HVQEYGS+C PN+RRVY++YLDS+HFF PR RT VYHE L+GYLEY KKLG+ HIWACPP EGDDYIFH HPP+QK+PKPKRLQEWY KMLDKA E ++ DY+DIF A + S ELPYFEGD+WPN LE+ KE+++E R K + T S+ E + ++ + + K + R N +K+ + ND+S+K+ MEK KE FFVI LHS LPPI DPD L DLMDGRD L LAR+KH EFSSLRR K+ST+C ELH + ++ +Y CN C +E R+ C CEDF+LC +CY T+ H H + K + D+++N + + P +++ R + R +SL HACQCR+ NC + C KMK +++H + C C +C+ + +C HAK C ++KC VP CL ++ +
Sbjct: 1044 KIFKPEELRQTLMPTLESLYRQDPESLPFRQPVDPMLLGIPDYFDIVKNPIDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKYCSKLAEVFESEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPTGGTYYSYQN---------------RYHFCEKCFNDIQGDSVTLGDDPAQPQTMISKDQFERKKNDVLDPEPFVECKDCGRKMHQICVLHYEVIWPSGFICENCLKKSGKTKKENKFTAKRLQSTRLGMHIEDRVNKYLKRQNHPEAGEVFVRVVASSDKTVEVKPGMKARFVDTGEMPETFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSECSFPNNRRVYISYLDSIHFFRPRILRTAVYHEILIGYLEYVKKLGYAQGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYRKMLDKAFAERILHDYKDIFKQATEDRLTSANELPYFEGDFWPNVLEESIKELEQEEEERKKEEN-TAASEMPEGTPSDSKNAKKKNNKKTNKNKSSISRAN-----KKKPGMPNVANDLSQKLYATMEKHKEVFFVIHLHSGPMVNTLPPIVDPDPLISCDLMDGRDAFLTLARDKHWEFSSLRRCKWSTMCMLVELHNQGQDRFVYTCNECKHHVETRWHCTVCEDFDLCINCYNTKGHEHQMVKWGLGLDDDNNGQSGEASKSP--QESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLR 1812 HSP 2 Score: 82.4185 bits (202), Expect = 4.506e-15 Identity = 44/91 (48.35%), Postives = 57/91 (62.64%), Query Frame = 3
Query: 105 PLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGK-GDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLR 374
P D +KR LI+QQL L HA KC R G+ C HC M++V+ H+T CQ+GK C+ HC SS++II HWKNC +C VC PL+
Sbjct: 346 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEMRACALPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 436
BLAST of CREB-binding protein vs. Planmine SMEST
Match: SMESG000066809.1 (SMESG000066809.1) HSP 1 Score: 2654.4 bits (6879), Expect = 0.000e+0 Identity = 1322/1325 (99.77%), Postives = 1323/1325 (99.85%), Query Frame = 3
Query: 51 MTSSSEVMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNIRKSVSNKPKINGITNYNDQFNNDKEVNWRNTILSIRPNFLVKLTDELIPVKVCEDVKNHSGYIDVSNYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGNMKDNLEFGTIKKELVANEIPMTPDKEYEQKLAYGSYIKTESWTENDIDSKRELLESSPNAAAKSTPVKLPATQLSTDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCSIPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHPETPCPTSVPLQSQTSITSINTQPPSIDAPTATILPEKISEPNESDTCKRNNIVMQNKSSTPNNHVQSYNSQSETPFCSXXXXXXXXXXXXXXXXMDSRITDDIKLVYDRYNFYLSNIPNKEDFQKTFGTWLNNNPKYRLAFDMLCKRSKRQNDGM 4025
MTSSSEVMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNIRKSVSNKPKINGITNYNDQFNNDKEVNWRNTILSIRPNFLVKLTDELIPVKVCEDVKNHSGYIDVSNYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGNMKDNLEFGTIKKELVANEIPMTPDKEYEQKLAYGSYIKTESWTEN+IDSKRELLESSPNAAAKSTPVKLPATQLSTDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLF EIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSKMDKKPKKRKLKRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCSIPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKQQGSQQRMQQAQMLRRRVALMQRGMHPETPCPTSVPLQSQTSIT INTQPPSIDAPTATILPEKISEPNESDTCKRNNIVMQNKSSTPNNHVQSYNSQSETPFCSANANAVYNNNNNVNYAMDSRITDDIKLVYDRYNFYLSNIPNKEDFQKTFGTWLNNNPKYRLAFDMLCKRSKRQNDGM
Sbjct: 1 MTSSSEVMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNIRKSVSNKPKINGITNYNDQFNNDKEVNWRNTILSIRPNFLVKLTDELIPVKVCEDVKNHSGYIDVSNYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGNMKDNLEFGTIKKELVANEIPMTPDKEYEQKLAYGSYIKTESWTENEIDSKRELLESSPNAAAKSTPVKLPATQLSTDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLFTEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSKMDKKPKKRKLKRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCSIPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKQQGSQQRMQQAQMLRRRVALMQRGMHPETPCPTSVPLQSQTSITPINTQPPSIDAPTATILPEKISEPNESDTCKRNNIVMQNKSSTPNNHVQSYNSQSETPFCSANANAVYNNNNNVNYAMDSRITDDIKLVYDRYNFYLSNIPNKEDFQKTFGTWLNNNPKYRLAFDMLCKRSKRQNDGM 1325
BLAST of CREB-binding protein vs. Planmine SMEST
Match: SMESG000066809.1 (SMESG000066809.1) HSP 1 Score: 1513.43 bits (3917), Expect = 0.000e+0 Identity = 777/779 (99.74%), Postives = 777/779 (99.74%), Query Frame = 3
Query: 1689 ACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCSIPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKXXXXXXXXXXXXXXXXXVALMQRGMHPETPCPTSVPLQSQTSITSINTQPPSIDAPTATILPEKISEPNESDTCKRNNIVMQNKSSTPNNHVQSYNSQSETPFCSXXXXXXXXXXXXXXXXMDSRITDDIKLVYDRYNFYLSNIPNKEDFQKTFGTWLNNNPKYRLAFDMLCKRSKRQNDGM 4025
CKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSKMDKKPKKRKLKRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCSIPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKQQGSQQRMQQAQMLRRRVALMQRGMHPETPCPTSVPLQSQTSIT INTQPPSIDAPTATILPEKISEPNESDTCKRNNIVMQNKSSTPNNHVQSYNSQSETPFCSANANAVYNNNNNVNYAMDSRITDDIKLVYDRYNFYLSNIPNKEDFQKTFGTWLNNNPKYRLAFDMLCKRSKRQNDGM
Sbjct: 23 VCKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSKMDKKPKKRKLKRMNSLNNKRKRINGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPDALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSLFKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCSIPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRFNWKQQGSQQRMQQAQMLRRRVALMQRGMHPETPCPTSVPLQSQTSITPINTQPPSIDAPTATILPEKISEPNESDTCKRNNIVMQNKSSTPNNHVQSYNSQSETPFCSANANAVYNNNNNVNYAMDSRITDDIKLVYDRYNFYLSNIPNKEDFQKTFGTWLNNNPKYRLAFDMLCKRSKRQNDGM 801
BLAST of CREB-binding protein vs. Planmine SMEST
Match: SMESG000066809.1 (SMESG000066809.1) HSP 1 Score: 1123.61 bits (2905), Expect = 0.000e+0 Identity = 545/547 (99.63%), Postives = 546/547 (99.82%), Query Frame = 3
Query: 51 MTSSSEVMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNIRKSVSNKPKINGITNYNDQFNNDKEVNWRNTILSIRPNFLVKLTDELIPVKVCEDVKNHSGYIDVSNYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGNMKDNLEFGTIKKELVANEIPMTPDKEYEQKLAYGSYIKTESWTENDIDSKRELLESSPNAAAKSTPVKLPATQLSTDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAA 1691
MTSSSEVMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNIRKSVSNKPKINGITNYNDQFNNDKEVNWRNTILSIRPNFLVKLTDELIPVKVCEDVKNHSGYIDVSNYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGNMKDNLEFGTIKKELVANEIPMTPDKEYEQKLAYGSYIKTESWTEN+IDSKRELLESSPNAAAKSTPVKLPATQLSTDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLF EIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAA
Sbjct: 1 MTSSSEVMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGKGDCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNIRKSVSNKPKINGITNYNDQFNNDKEVNWRNTILSIRPNFLVKLTDELIPVKVCEDVKNHSGYIDVSNYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGNMKDNLEFGTIKKELVANEIPMTPDKEYEQKLAYGSYIKTESWTENEIDSKRELLESSPNAAAKSTPVKLPATQLSTDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLFTEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAA 547
BLAST of CREB-binding protein vs. Planmine SMEST
Match: SMESG000018938.1 (SMESG000018938.1) HSP 1 Score: 858.981 bits (2218), Expect = 0.000e+0 Identity = 477/1155 (41.30%), Postives = 702/1155 (60.78%), Query Frame = 3
Query: 48 KMTSSSEVMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRL-AYTTGKG-DCHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPLRPNNNIRKSVSNKPKINGITNYNDQFNNDKEVNWRNTILSIRPNFLVK-LTDELIPVKVCEDVKNHSGYIDVSNYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGNMKDNLEFGTIKKELVANEIPMTPDKEYEQKLAYGSYIKTESWTENDIDSKRELLESSPNAAAKSTPVKLPATQL--STDVKMSP--DSTSTPNKDHTNAHKKWSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQNDKSNGEKIISELTCDRYICCEKCYNDSCEDVQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEIDGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKRINGS-DTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPINDPD-ALFHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIEVRYTCKQCEDFELCPSCYTTETHPHSL----FKVDPDEESNILNSQNLSQPTSEDTTRARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKHFQCCS-IPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLRF 3470
++ +S M N K D +KR LI+QQL L HA +C R + G+ C+ HC MR+V+ H++ C GK+C HC SS++II HWKNC++ C VC PL+ N+N + + P + N +WR + + N L++ + + P + +K+ ++ Y + E E++ A + +Y + LAEK +++ L KR K+ S A + N QIE +++N EF + +++ + +EQ L Y +S ++ I K+EL+ A K P T+L S + P D+ + ++ + K+W+++EL F+ + I ++K++E F+ V++ L IPDYP ++K PMD+++I+ KL G Y +PWDVVDDFWLMF NAWLYNKKTS+VYK CS LA++FESKI+++M G+CCG + Y PQVL C + + C I +DA+Y+ ++N +G+ I L ++Y+ CEKCYN++ ++ +N + + V K + + RNNVK E+FV C +C RKWH VCA ++++IW G+ C +C+++ + + KPN + ++ LP LS Y+E RVN +LK ++ NEV++R+L+SSDK VEVKP M+ Y ET EM ESF YRLKA++AFQEIDG EVCFFGL+VQEYGSDCP PN+RRVY+AYLDSV++F PR+YRTDVYHE L+GYL +AKK F+MAHIW+CPPGEGDDYIFHMHPP+QK+PK KRL EWY+ ML KA+ E +V DY+DI D++ +++LSP E+PYF+GD+WPN LEDI KE +EE +R + E T T + + K K +K K N ++K +NG D ++ RKV ++MEK K FVIRL +A LP DPD A+ +SDLM+ RD L L REK+LEFSSLRR K+ST+ YE+H E++++ +Y C+ C +Q+E RY C +CE++++C C T+ HPH L F +D DE+ N + + + R + K+L HACQCRD NCRIN C +MK +++H + C+ + TC+ C+ + +CF HAK C +SKC +P C +++
Sbjct: 144 RLHNSQTQMQSINCFSEKSNSTDPEKRKLIQQQLLLLLHAHRCQRQESEVNGQSTSCNTPHCKTMRTVLSHMSNCSQGKNCSTPHCASSRQIISHWKNCSNPRCPVCEPLKQNHNRPRGIIPPPAQDFDPN-----------DWRRNVSKDQRNHLIRRIVQTIFPSRDPSAIKD-PRMSNLIEYARRTENEMYNMAKDREEYFHLLAEKCFKIHKELEQKR--KDRLSTGAGKLPNG--SQIEL----------AGVSTIHTCIENNDEFQKKPESTHNSDVQV----RFEQVLR-DKYTNNQS-SQPSIPVKKELV-------AAEIDQKPPETELIKSENTTEEPIIDNVTVKHEQEVSTIKQWTTDELKTNFLPMWNEIYNEKNAEWFREKVDYVALQIPDYPLVIKHPMDMTSIRMKLEAGKYKDPWDVVDDFWLMFKNAWLYNKKTSRVYKACSKLAEVFESKINNLMKKLGYCCGMHYSYEPQVLFCNSVHACTIPKDAIYFEYEN---SGKSQI--LAGEKYLICEKCYNEADLTIK-LNDDPQQDSEIVDKDMFRQLRNNVKVEEKFVNCILCMRKWHCVCALYMEEIWSSGYLCPSCLQKTNQRRKPNKFTARKLPTSCLSNYLERRVNDFLKKKEANANEVVIRILASSDKTVEVKPLMRGRYAETNEMSESFPYRLKAIYAFQEIDGVEVCFFGLYVQEYGSDCPQPNTRRVYIAYLDSVYYFQPRQYRTDVYHEILLGYLMFAKKNHFSMAHIWSCPPGEGDDYIFHMHPPDQKIPKEKRLIEWYVNMLRKALIELIVADYKDILKDSIENNLLSPAEIPYFDGDFWPNTLEDILKEYEEEVEKRRMEENSIGGDDEITTDYT-TVDYDKRGKKKAKKRKEKRGNCTIPNKRKKMVNGGFDGGTELCRKVYDVMEKVKHLLFVIRLIPSQEAHLLPDTKDPDGAVINSDLMESRDAFLQLCREKNLEFSSLRRGKYSTMVMLYEIHNERRHNFMYNCSECGEQMETRYHCNECEEYDICVKCKETKQHPHKLHMIGFCLDEDEKDN--------EQEAVKSKRVGIDNCIKALLHACQCRDANCRINNCLRMKRIVQHTKTCNKKAQGTCETCKQLIALCFYHAKICKESKCHIPFCHSIKY 1244
BLAST of CREB-binding protein vs. Planmine SMEST
Match: SMESG000060474.1 (SMESG000060474.1) HSP 1 Score: 838.565 bits (2165), Expect = 0.000e+0 Identity = 462/1132 (40.81%), Postives = 663/1132 (58.57%), Query Frame = 3
Query: 210 CHNQHCIMMRSVVKHITKCQSGKDCKFQHCPSSKEIIKHWKNCNDVECQVCAPL--RPNNNIRKSVSNKPKINGITNYNDQFNNDKEVNWRNTILSIRPNFLVKLTDELIPVKVCEDVKNHSGYIDVSNYVKSFEFEIFQKAININDYLYKLAEKFAMVYQLLLSKRNPKENESILAHNITNNPTKQIEKFFQLIKSEFDKFFIAFKGNMKDNLE--FGTIKK---ELVANEIPMTP---DKEYEQKLAYGSYIKTESWTENDIDSKRELLESSPNAAAKSTPVKLPATQLSTDVKMSPDSTSTPNKDHTNAHKKWSSEELSDLFMEIHQLILSDKDSEPFKLPVNWELLDIPDYPSIVKCPMDLSTIKDKLVNGLYNNPWDVVDDFWLMFNNAWLYNKKTSKVYKMCSTLAKLFESKIDDIMVSCGFCCGREFVYLPQVLICCTPNVCLIVRDAVYYAFQN--DKSNGEKIISELTCDRYICCEKCYNDSCED-VQFINAENNGAACKVQKSLLSKCRNNVKENEEFVFCRICNRKWHKVCANHIDDIWRDGFYCATCIREKSIKIKPNVYKSKGLPHCELSRYIENRVNKYLKDRDPTINEVIVRVLSSSDKVVEVKPGMKSHYCETCEMPESFKYRLKAVFAFQEI-DGQEVCFFGLHVQEYGSDCPDPNSRRVYLAYLDSVHFFSPRKYRTDVYHEFLVGYLEYAKKLGFTMAHIWACPPGEGDDYIFHMHPPEQKLPKPKRLQEWYIKMLDKAIKENVVIDYRDIFSDALNSSMLSPTELPYFEGDYWPNALEDIFKEIDEETNRRLKSYSETPNSQEGETSQTEVISKNNLSXXXXXXXXXXXXRMNSLNNKRKR---INGSDTINDVSRKVLELMEKRKENFFVIRLHSQSDAANLPPI---NDPDAL-FHSDLMDGRDKLLCLAREKHLEFSSLRRAKFSTLCFCYELHMEQKNSVLYACNACNKQIE-VRYTCKQCEDFELCPSCYTTETHPHSLFKV-----DPDEE-----------------SNILNSQNLSQPTSEDTT-RARMVRYSKSLQHACQCRDVNCRINLCAKMKGMIKH-FQCCSIPKSTCKMCQLFLRICFVHAKFCSDSKCQVPNCLVLR 3467
C++ +C S++ HI C +DC + C S+ +KH+ NC +C VC + NNI G+ + ++ + WR I RP+ L ++++EL K+ + + F+ F+ + I YL A+ N N+ H NP + + + I N KDN++ F +K+ +++ N + + P E ++++ + IK+E D+ + E +S N+++ + P + + +K SP S K + + K W + EL LF +H I +KD+ F PV+WE DIPDYP I+ PMDLSTIK KL +G Y +PW V+ D+WL+FNNAW YNKK+S+VYKMCS LA++FE + D M S G CCGR+FVYLPQ+L CCTP +C++ RDA+Y+ N D+SNG+K++ EL D+++CC+KC+ND+ +D +Q + ++ A V+KSL +K +NNVKE EEF+ C+IC +KWHKVCA H+D+IW GFYC C + + NV S LP C LSR+IE RV+ + + +I +V +RVLS S K E+K MK + E EMPES Y+ KA+FAFQE+ DG E+C FG+H QEYGSDCP PN+RRVYLAYLDSV+FF P RTD YH L+ YLEY ++LGF AHIWACPPGEGDDYIFHMHPP QKLPKPKRLQ+WYI MLDKAI E +V++Y DIF+ + NS ++S +E+PYFEGDYWPN LED+ KE S ++ +E + + +N S K +K K +NS N+KR+R ++ + ND+ +++ + +E+RKENFFV+RLHSQSDA+ LP + +D D + F+SDLMDGRDK L L+R+KHLEFSS+RRAKF+TL CYELH+E ++ V+Y+CN+C+ ++ +RYTC+ CE+FELC C HPH L + DP E N + + P E R + + + K +HA +CRD +C+I CA+ + + H C + +CK C+ I H + C + C++ C+ R
Sbjct: 34 CNHTNCPKFMSILDHIKSCDKAEDCNTRCCISNISYMKHYLNCLQSKC-VCFRFGDKSENNIL--------FAGVKHI---LLRNQYIIWRRKIDPFRPHLLWRISEELSSF-----TKDKTSRDIFFRCISEFDKNNFENSKGIIIYLNNFAKN-----------ANDILNKIQWKHIRCQNPNLSYQDYVEQI-------------NEKDNIQKIFNYLKRYSTDVLHNRMRLEPVPVSNEIKEEITIKNEIKSEMSVNTDVKIEPETQDSPTNSSSLTPPKSI------SSLKTSPSVASIDEKPN-QSEKVWVARELEYLFEPLHSKICHEKDATIFLAPVDWEAEDIPDYPKIISHPMDLSTIKRKLADGDYQDPWHVIADYWLIFNNAWTYNKKSSRVYKMCSNLARIFELEADKTMQSIGLCCGRDFVYLPQILTCCTPQMCMVGRDALYHVLNNEEDESNGDKLVPELASDKFLCCDKCFNDATDDSIQLMLNDSTTALVAVKKSLFTKMKNNVKEREEFIKCKICLKKWHKVCAEHMDEIWGSGFYCPDCESNRRFPKQKNVLISAELPQCNLSRHIEARVDAWRQKESQSIAKVNIRVLSISTKSAEIKSEMKRIFVENGEMPESLPYKSKAIFAFQELSDGSEICLFGMHTQEYGSDCPSPNTRRVYLAYLDSVNFFQPSNLRTDFYHRLLISYLEYCQQLGFIFAHIWACPPGEGDDYIFHMHPPSQKLPKPKRLQDWYIAMLDKAILEGIVVEYSDIFAYSYNSQLMSLSEMPYFEGDYWPNVLEDLLKE------DSALSAADLMLEEELRAPDSMIEQQNGFSNSYSKKRKLKKMSINS-NSKRRRQSDLSDGNNNNDIMKRLFDNLERRKENFFVVRLHSQSDASKLPAVIIDSDCDGIKFNSDLMDGRDKFLALSRDKHLEFSSIRRAKFATLSLCYELHLELRHGVIYSCNSCDLMLDSIRYTCQVCEEFELCDRCVRELGHPHKLHRTPSCQDDPSESVDSSSGNEDRHQSIAAIGNPVTVPAFAPPQDEGAIKRQKTIVFIKMYEHADKCRDASCKIANCARFRRIPDHTIDCAKKNERSCKFCKQIFNIIREHQRDCRNIDCRLEVCIRKR 1110 The following BLAST results are available for this feature:
BLAST of CREB-binding protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of CREB-binding protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of CREB-binding protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of CREB-binding protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of CREB-binding protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of CREB-binding protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of CREB-binding protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of CREB-binding protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of CREB-binding protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of CREB-binding protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of CREB-binding protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 4
BLAST of CREB-binding protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of CREB-binding protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of CREB-binding protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002665 ID=SMED30002665|Name=CREB-binding protein|organism=Schmidtea mediterranea sexual|type=transcript|length=5118bpback to top protein sequence of SMED30002665-orf-1 >SMED30002665-orf-1 ID=SMED30002665-orf-1|Name=SMED30002665-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1637bp MTSSSEVMSVENTDKNKQPLVDSDKRFLIRQQLYYLFHASKCTRLAYTTGback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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