TNF receptor-associated factor
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002663 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 14
Homology
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 185.652 bits (470), Expect = 1.288e-50 Identity = 146/555 (26.31%), Postives = 242/555 (43.60%), Query Frame = 3
Query: 312 MPEKYNYTENFRNSQSRSIFFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNH-SETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQ---MTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGD--KVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTN---QSLHEE----------------------LQLVKGINKDLLKI-----------------------VEKLQKQLTENESIILN----------IKSEMEKQKQLIASPSINNEN--------QINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
+PE+ Y E F + + +KC C V P QTECG RFC +C+ +++S+ C C I ++K +D ++EI +I C NE C E +L L H C + C C++ K H+ + C+ R TC C+ Q + HE D C + CP +CS + + HL EC N+ C F GC + T +I H + QH L L + + L++ N QSLH + L L + I+ K+ VE LQ ++TE ES+ + ++S++ + Q+++ I + + NG L+W I + +++ +A G + + S+PFY+ GY+M ++Y NGDG GK +LS++F+I++GEYD + WPF+QKV+L ++ S+R+++ KPD N + + KP N+ +G P F+ + +L + Y+ +I + + V TS
Sbjct: 33 VPEQGGYKEKFVKT-------------VEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHE----------DTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTS 563
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 185.652 bits (470), Expect = 1.288e-50 Identity = 146/555 (26.31%), Postives = 242/555 (43.60%), Query Frame = 3
Query: 312 MPEKYNYTENFRNSQSRSIFFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNH-SETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQ---MTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGD--KVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTN---QSLHEE----------------------LQLVKGINKDLLKI-----------------------VEKLQKQLTENESIILN----------IKSEMEKQKQLIASPSINNEN--------QINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
+PE+ Y E F + + +KC C V P QTECG RFC +C+ +++S+ C C I ++K +D ++EI +I C NE C E +L L H C + C C++ K H+ + C+ R TC C+ Q + HE D C + CP +CS + + HL EC N+ C F GC + T +I H + QH L L + + L++ N QSLH + L L + I+ K+ VE LQ ++TE ES+ + ++S++ + Q+++ I + + NG L+W I + +++ +A G + + S+PFY+ GY+M ++Y NGDG GK +LS++F+I++GEYD + WPF+QKV+L ++ S+R+++ KPD N + + KP N+ +G P F+ + +L + Y+ +I + + V TS
Sbjct: 33 VPEQGGYKEKFVKT-------------VEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHE----------DTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTS 563
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF5 (TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035]) HSP 1 Score: 181.03 bits (458), Expect = 5.425e-49 Identity = 138/526 (26.24%), Postives = 249/526 (47.34%), Query Frame = 3
Query: 390 QLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYIN-NSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNE-RCDEIFLLKELKNHSETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKM----HLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLE---STNQSLHEEL------------------------------------------QLVKGIN--------KDLLKIVEKLQKQLT---ENESIILNIKSEMEKQKQLI---ASPSINNENQINLV-----NGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLD-YLHGTSIKLAIKVQTS 1748
+L +KC+ C +V P QT CG RFC +CI + N+ CP I + +D ++E+ N + C N C+ +L ++H + C ++ QC + C++ K ++H++ C+ R C C++ + IN +N E +NLC ++ CP C+ K+++K HL CP ++ +CPF + GC + +H +H ++ + VQL + ++L SLE S Q L E + QL++ +N + L++ V+ +++++T N+ + ++ E K I + NE + L+ NG+L+W + + + K +A G+ V I S+ FY+ R GYR+ + Y NGDG G+ +LS+YF++++GE+D + WPFRQ+V+L +L +S ++NI KPD N + + +P N+ +G P F+ S L + + Y+ ++ L + V +
Sbjct: 38 RLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVV----INLQNHE---ENLCPEYPVFCPNNCA---KIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLL-DQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDLT 552
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF5 (TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035]) HSP 1 Score: 181.03 bits (458), Expect = 5.425e-49 Identity = 138/526 (26.24%), Postives = 249/526 (47.34%), Query Frame = 3
Query: 390 QLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYIN-NSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNE-RCDEIFLLKELKNHSETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKM----HLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLE---STNQSLHEEL------------------------------------------QLVKGIN--------KDLLKIVEKLQKQLT---ENESIILNIKSEMEKQKQLI---ASPSINNENQINLV-----NGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLD-YLHGTSIKLAIKVQTS 1748
+L +KC+ C +V P QT CG RFC +CI + N+ CP I + +D ++E+ N + C N C+ +L ++H + C ++ QC + C++ K ++H++ C+ R C C++ + IN +N E +NLC ++ CP C+ K+++K HL CP ++ +CPF + GC + +H +H ++ + VQL + ++L SLE S Q L E + QL++ +N + L++ V+ +++++T N+ + ++ E K I + NE + L+ NG+L+W + + + K +A G+ V I S+ FY+ R GYR+ + Y NGDG G+ +LS+YF++++GE+D + WPFRQ+V+L +L +S ++NI KPD N + + +P N+ +G P F+ S L + + Y+ ++ L + V +
Sbjct: 38 RLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVV----INLQNHE---ENLCPEYPVFCPNNCA---KIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLL-DQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDLT 552
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF5 (TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035]) HSP 1 Score: 181.03 bits (458), Expect = 5.425e-49 Identity = 138/526 (26.24%), Postives = 249/526 (47.34%), Query Frame = 3
Query: 390 QLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYIN-NSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNE-RCDEIFLLKELKNHSETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKM----HLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLE---STNQSLHEEL------------------------------------------QLVKGIN--------KDLLKIVEKLQKQLT---ENESIILNIKSEMEKQKQLI---ASPSINNENQINLV-----NGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLD-YLHGTSIKLAIKVQTS 1748
+L +KC+ C +V P QT CG RFC +CI + N+ CP I + +D ++E+ N + C N C+ +L ++H + C ++ QC + C++ K ++H++ C+ R C C++ + IN +N E +NLC ++ CP C+ K+++K HL CP ++ +CPF + GC + +H +H ++ + VQL + ++L SLE S Q L E + QL++ +N + L++ V+ +++++T N+ + ++ E K I + NE + L+ NG+L+W + + + K +A G+ V I S+ FY+ R GYR+ + Y NGDG G+ +LS+YF++++GE+D + WPFRQ+V+L +L +S ++NI KPD N + + +P N+ +G P F+ S L + + Y+ ++ L + V +
Sbjct: 38 RLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVV----INLQNHE---ENLCPEYPVFCPNNCA---KIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLL-DQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDLT 552
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80]) HSP 1 Score: 135.191 bits (339), Expect = 7.291e-34 Identity = 111/454 (24.45%), Postives = 181/454 (39.87%), Query Frame = 3
Query: 357 SRSIFFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNHSETCQYRMK-QCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDK--VVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSS---KSARQNITLNMKP---DNNVACYGKPINNSNVGAGQPEFIKLSEL 1685
S+S+ F L + C +C+ +PI+ C +C C EN N C C I D+A +K+I + C E C L L +H C ++ +C+ C + + E+H + CE C C + + +D E + + C + I CP +C D+ + I+ H CPN CPF GCT I +HL E +H +L EI L+ ++ + S N ++Q +++++ E + +L+W I+ ++Q+ ++AKSG I S PF S R GY+M GDG K +S+Y ++++GE+D + WPF + + +S+L R NIT + P N +P N G F L+ L
Sbjct: 3 SQSVMFKGG---LPADCTCPICEQALRDPIKLNCDHHYCRQCFEN--ENRTPGCAACQTIIQPELCQHDRAKQKQILALPVVCTFESSGCPWDGQLGTLHDHLSECTFKSSLKCEKCGRQFAKNDLEKHRAK-CELNRAVCSFCNKTIRDSDRERHPKT--------CPQVIISCPFQCGLTDRPRLEIEAHCPSCPNVDNVCPFVPYGCTFAGGKESIQQHLSDEPVRHLMYLCDEITDLKGTYELMERDMGSFN------------------------------------------DRQTRILSA----AETCTEMFGPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPRPEDRVNITYVIDPRKLKANEKFLARPRGERNAAFGSQSFCSLAIL 396
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-2 (TNF Receptor Associated Factor (TRAF) homolog [Source:UniProtKB/TrEMBL;Acc:Q9N586]) HSP 1 Score: 66.2402 bits (160), Expect = 1.660e-11 Identity = 56/209 (26.79%), Postives = 89/209 (42.58%), Query Frame = 3
Query: 930 PNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILS 1556
P++ I+CPF GC + +E+ +H+ + H L + +RT+ N QS + + K V LQ ++ ES E + P I + +++ + K H + I S+PFYS GY+M P GDG +Y SV+ +++GE+DD + WPFR V+ SILS
Sbjct: 80 PDNWIDCPFKEHGCHKKGENSEVKRHVRDDRNLHLVLLCQSLNPIRTKIN--------IQQSAYVD------------KYVGMLQ-YMSIAESAF-----EKYGSQHTFRIPKIG------------LTVVKATKNKSHRS-------IYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSILS 243
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0077429) HSP 1 Score: 114.39 bits (285), Expect = 1.216e-26 Identity = 97/391 (24.81%), Postives = 179/391 (45.78%), Query Frame = 3
Query: 597 IKCPNERCDEIFLLKELKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCD-DCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCP--QRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEI-VQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSIL--SSKSARQNITLNMKPDNNVACYGKPINNSN-VGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
+CPN+ +I + + TC R +C+ CQ + E+H N C + V C+ C Q++ + H++ + C K + C QR + D + +H +CP + + CP R I + GE+ LR E +L S S E KG + L L+ + S+++ + S +Q Q++ S ++ IN G L+W I + K+ +A+ + ++++S PFY+ + GY+++ ++ NG+G G++ ++SVY ++ GEYD + WPF ++ ++ ++S + + + PD + +P N + +G G P FI ELL S ++ G ++ L +KV S
Sbjct: 134 TQCPNKCGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSGAGLEEH-NGSCGQEPVYCEAKCGQRILRGRMTL-HKSKD------CAKRLRRCAHCQREFSAD--TLPLHAAQCPRAPLACP-------QRCDAGPIPR--------------GELEAHLRDECQSLAVSC-----SFKEAGCRFKGPRQML---EAHLESNAAAHLSLMVALSSRQGQQIQMLKS--AVSKLSINYT-GTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFIS-HELLHSRPFIKGDTVFLRVKVDPS 481
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0334401) HSP 1 Score: 114.005 bits (284), Expect = 1.677e-26 Identity = 96/390 (24.62%), Postives = 180/390 (46.15%), Query Frame = 3
Query: 600 KCPNERCDEIFLLKELKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCD-DCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCP--QRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEI-VQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSIL--SSKSARQNITLNMKPDNNVACYGKPINNSN-VGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
+CPN+ +I + + TC R +C+ CQ + E+H N C + V C+ C Q++ + H++ + C K + C QR + D + +H +CP + + CP R I + GE+ LR E +L + + S E KG + L L+ + S+++ + S +Q Q++ S ++ IN G L+W I + K+ +A+ + ++++S PFY+ + GY+++ ++ NG+G G++ ++SVY ++ GEYD + WPF ++ ++ ++S + + + PD + +P N + +G G P FI ELL S ++ G ++ L +KV S
Sbjct: 126 QCPNKCGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSGAGLEEH-NGSCGQEPVYCEAKCGQRILRGRMTL-HKSKD------CAKRLRRCAHCQREFSAD--TLPLHAAQCPRAPLACP-------QRCDAGPIPR--------------GELEAHLRDECQSL-----AVSCSFKEAGCRFKGPRQML---EAHLESNAAAHLSLMVALSSRQGQQIQMLKS--AVSKLSINYT-GTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFIS-HELLHSRPFIKGDTVFLRVKVDPS 472
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0074275) HSP 1 Score: 59.3066 bits (142), Expect = 6.292e-9 Identity = 62/253 (24.51%), Postives = 119/253 (47.04%), Query Frame = 3
Query: 1002 KHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSE-------LLTSLDYLHGTSIKLAIKV 1739
K +IE F Q + E ++ + N++ S ++T L E++ VK I + + +KL + L + I +++++M Q+++ S+ N + G L+W I++ +K+ ++K + + + S F + GY +RL IY NG G K + + ++ GEYD + WP R + + I R T NVA + V +FI+ ++ ++TS +YL S+ + ++V
Sbjct: 249 KFFQIEEFLQQ---INEDIKTKLGNSDYVTSKQAT---LDYEVKNVKNIVCETEERCDKLDRALHQTMQNISDLETQMAMQQRI---ASVQN------IRGHLIWRIKDYSKKLEESKQYDTI-LHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIII------RDQCT-------NVADAEDYVKTIFVRKKSDDFIQSNQYFHIPHKVITSRNYLRNDSMFIEVRV 472
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf6 (gene:FBgn0265464 transcript:FBtr0071188) HSP 1 Score: 59.3066 bits (142), Expect = 6.878e-9 Identity = 62/293 (21.16%), Postives = 124/293 (42.32%), Query Frame = 3
Query: 891 GDKVVIKMHLKECP------NSQINCPFSNVGC--TTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLH---------EELQLVKGINKDLLKIVEK----LQKQLTENESIILNIKSEME-KQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRM--RLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSA--RQNITLNMKPDNNVACYGKPINN-SNVGAGQPEFIKLSELL 1688
+ + HL CP + CPF+ + C R N++ +HL+ + H LM + Q H ++ ++ Q G+++ +++ + + L+++ E E+ + N++ ++ ++Q P +N G +VW IE + + ++ Q+ S Y+ GY+ RL I P K LS++ ++Q E D + WPF+ ++ L ++ A Q+ T+ KP+ + + KP S G G E+ +S ++
Sbjct: 180 ASPIELHRHLPSCPYRRQQEPQEEKCPFAKIKCDFVGRPETNQLEEHLKAD-MPHHMQLMLQAFQQTAIATWQPHKPSTSGAAVENGHGQQQLPPPPQYANGVDEQIVQTMYQRIVVLEQRTREQETRLENMQKQLRLARQQAPVDPRYSN--------GTIVWRIEQLGALVARLRANANNQVYSHECYTSPHGYKFCARLNIQPR-----KPHVLSLHVHLMQSENDYHLDWPFKGRIKLCMVHPADATLSQHDTIMTKPE--ILAFHKPREAISTRGFGFLEYANISNII 456 HSP 2 Score: 55.0694 bits (131), Expect = 1.412e-7 Identity = 33/102 (32.35%), Postives = 49/102 (48.04%), Query Frame = 3
Query: 393 LSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCP--NCDLEINRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNHSETCQYRMKQ 686
L ++C++C + EP+ T CG RFC +C+ ++ +N CP N L + F D +EI K CPN C + EL H +C YR +Q
Sbjct: 98 LDSRYECAICIDWLNEPVLTSCGHRFCRSCLTAWMQKNNQCCPMDNKRLSAEHDIFP-DNYTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSCPYRRQQ 198
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0074273) HSP 1 Score: 58.9214 bits (141), Expect = 8.519e-9 Identity = 62/253 (24.51%), Postives = 119/253 (47.04%), Query Frame = 3
Query: 1002 KHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSE-------LLTSLDYLHGTSIKLAIKV 1739
K +IE F Q + E ++ + N++ S ++T L E++ VK I + + +KL + L + I +++++M Q+++ S+ N + G L+W I++ +K+ ++K + + + S F + GY +RL IY NG G K + + ++ GEYD + WP R + + I R T NVA + V +FI+ ++ ++TS +YL S+ + ++V
Sbjct: 227 KFFQIEEFLQQ---INEDIKTKLGNSDYVTSKQAT---LDYEVKNVKNIVCETEERCDKLDRALHQTMQNISDLETQMAMQQRI---ASVQN------IRGHLIWRIKDYSKKLEESKQYDTI-LHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIII------RDQCT-------NVADAEDYVKTIFVRKKSDDFIQSNQYFHIPHKVITSRNYLRNDSMFIEVRV 450
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf3 (TNF receptor-associated factor 3 [Source:ZFIN;Acc:ZDB-GENE-040801-257]) HSP 1 Score: 185.267 bits (469), Expect = 1.423e-50 Identity = 127/521 (24.38%), Postives = 239/521 (45.87%), Query Frame = 3
Query: 411 CSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNHSETCQYRMKQCDL--CQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGD--KVVIKMHLKECPNSQINCPFSNVGCTTRATVNEI--------NKHLEIESFQHQTF------LMGEIVQ---------------------LRTENNNLKHSLESTN-----------------------QSLHEELQLVKGINKDLLKIVEKLQKQLTENES---IILNIKSEMEKQKQLIASPSIN-NENQINL-------VNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
C C+ V P QTECG RFC +CI ++ N CP L + +K RD +EI K+ C +E+ C E L+++ H C Y C L C++ K +H++ C+ R VTC+ C +M + + H+ + +C + CP CS + + H +CP +Q+ C F GC+ + E+ ++HL + + ++ T + E+++ +R +N L+ L S +++ EE++ ++G + + +V L + S + +++ ++ + L++ + E + L NG L+W I + +++ +A + + S+PFY+ GY+M ++Y NGDG GK +LS++F++++GEYD + WPF+QKV+L ++ AR+++ KPD + + + +P N+ +G P F+ + +L + Y+ +I + + V TS
Sbjct: 56 CETCRLVLCNPRQTECGHRFCESCINELLSKPNPVCPADLLPLFEDKIFRDVCCNREIMALKVYCRSEKNGCKEQMCLQQVMEHLVICPYFEVPCPLGKCKEKMMRKDMPEHLSRKCKHREVTCEFCSLKMALTELQ-KHK------ETVCPAFPVACPNHCSFSSILRSELSSHQHDCPKAQVTCSFIRYGCSYKGLNQEMREHESSFASEHLRMMAVRNTTLEAKVEDVKSELMERYKVLPSLSSRLAEVERQYEEMREKNRQLEQKLVSMQMLMSSHSEKLLEVEMELRELRPLRAMREEVETLRGSVESMRSMVSSLDSSCVNSASGSHTLASLEQQLTRHDDLMSVHDVRLAEMDLKLQVLETASFNGTLIWKIRDYKRRKQEAVVSKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLQWPFKQKVTLMLMDQGPARKHLGDAFKPDPSSSSFRRPTGEMNIASGCPLFVAQT-VLENGTYIKDDTIFIKVTVDTS 568
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 179.489 bits (454), Expect = 7.185e-49 Identity = 131/494 (26.52%), Postives = 214/494 (43.32%), Query Frame = 3
Query: 405 FKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLE---------INRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKN-HSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVI-----KMHLKECPNSQINCPFSNVGCTTRATVNEINK--HLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHE--ELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQK------------------------------------QLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSI 1721
++C CK++ +P Q +CG RFC C + ++ C C E +N D A +EI + KCPNE C LK+ +N H C + +C+ CQ L K++H CE R + C C+ +T N EI D +C K+ P +C + K I + H K C S+ C F +GC RA V+ + H + +H ++ + +R E L+ E G + +QK++T E+I+ + E+E+ QL S E Q +G +W I ++ DA +G + S FYS + GY+M L++Y NGDG G+ +LS++F++++G+YD + WPF QKV+L +L ++ R++I +PD + + +PI+ N+ +G P F L++L YL +I
Sbjct: 43 YQCQQCKDILRKPFQAQCGHRFCVFCFKQLTSSGPIPCEACRAEGIFEEETSVLNIAVAFPDNAARREIDSLPAKCPNEGCSWSGTLKDFENQHEGRCAFERVKCEACQVLILLSEKDRHNERECEARTLNCKYCK--VTFNFKEIKAH------DEICQKF----PMQCKDCGKKKIPREKFQEHTKSCAKSKSACQFREIGC--RAVVDNCKQQEHEQTSIMEHLRLMLALLSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVERSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLL-DQNNREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTI 521
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 179.489 bits (454), Expect = 7.185e-49 Identity = 131/494 (26.52%), Postives = 214/494 (43.32%), Query Frame = 3
Query: 405 FKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLE---------INRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKN-HSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVI-----KMHLKECPNSQINCPFSNVGCTTRATVNEINK--HLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHE--ELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQK------------------------------------QLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSI 1721
++C CK++ +P Q +CG RFC C + ++ C C E +N D A +EI + KCPNE C LK+ +N H C + +C+ CQ L K++H CE R + C C+ +T N EI D +C K+ P +C + K I + H K C S+ C F +GC RA V+ + H + +H ++ + +R E L+ E G + +QK++T E+I+ + E+E+ QL S E Q +G +W I ++ DA +G + S FYS + GY+M L++Y NGDG G+ +LS++F++++G+YD + WPF QKV+L +L ++ R++I +PD + + +PI+ N+ +G P F L++L YL +I
Sbjct: 43 YQCQQCKDILRKPFQAQCGHRFCVFCFKQLTSSGPIPCEACRAEGIFEEETSVLNIAVAFPDNAARREIDSLPAKCPNEGCSWSGTLKDFENQHEGRCAFERVKCEACQVLILLSEKDRHNERECEARTLNCKYCK--VTFNFKEIKAH------DEICQKF----PMQCKDCGKKKIPREKFQEHTKSCAKSKSACQFREIGC--RAVVDNCKQQEHEQTSIMEHLRLMLALLSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVERSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLL-DQNNREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTI 521
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 179.489 bits (454), Expect = 8.543e-49 Identity = 131/494 (26.52%), Postives = 214/494 (43.32%), Query Frame = 3
Query: 405 FKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLE---------INRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKN-HSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVI-----KMHLKECPNSQINCPFSNVGCTTRATVNEINK--HLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHE--ELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQK------------------------------------QLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSI 1721
++C CK++ +P Q +CG RFC C + ++ C C E +N D A +EI + KCPNE C LK+ +N H C + +C+ CQ L K++H CE R + C C+ +T N EI D +C K+ P +C + K I + H K C S+ C F +GC RA V+ + H + +H ++ + +R E L+ E G + +QK++T E+I+ + E+E+ QL S E Q +G +W I ++ DA +G + S FYS + GY+M L++Y NGDG G+ +LS++F++++G+YD + WPF QKV+L +L ++ R++I +PD + + +PI+ N+ +G P F L++L YL +I
Sbjct: 56 YQCQQCKDILRKPFQAQCGHRFCVFCFKQLTSSGPIPCEACRAEGIFEEETSVLNIAVAFPDNAARREIDSLPAKCPNEGCSWSGTLKDFENQHEGRCAFERVKCEACQVLILLSEKDRHNERECEARTLNCKYCK--VTFNFKEIKAH------DEICQKF----PMQCKDCGKKKIPREKFQEHTKSCAKSKSACQFREIGC--RAVVDNCKQQEHEQTSIMEHLRLMLALLSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVERSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLL-DQNNREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTI 534
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 153.68 bits (387), Expect = 4.021e-40 Identity = 127/510 (24.90%), Postives = 211/510 (41.37%), Query Frame = 3
Query: 405 FKCSLCKNVFIEPIQ-TECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKC--PNERCDEIFLLKELKNHSETCQYRMKQC-DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNI-----------------------------------------EMGIDNL------CDKWIDVCPQRCS--NGDKVVIKMHLKE-CPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSIL----SSKSARQNITLNMKPDNNVACYGKP------INNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQ 1742
F+C LC EP+Q + CG RFC C++ +++ CP L ++ K D +E++I I+C E C +K+L++H TC + + C + C + +H+ C +R V C+ C + T +E NH+ I E D + C ++ CP +C N + + H+KE C ++ + CPF GC R I +HLE + H T + + + R E IL ++ EME+ S+++ +G L+W + + +K+ +AK N + S PFY+ R GY++++ + NG+G G+ +LS+Y ++ GEYD+ + WPF KV+ SIL S S Q+IT PD N + KP ++ S +G G P+FI E + +Y+ SI L ++
Sbjct: 16 FQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCPNRCSVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAYE-NHQGICPQESVYCENKCGARMMRRLLSQHTMTECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLANHVKESCGSALVLCPFKEAGCKHRCPKMAIGRHLEESTKSHLTMMCSLVGRQRQE----------------------------------------------ILELRREMEEL-------SVSH-------DGVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSSRNSLDESTLGFGYPKFISHEE-IKKRNYIRDNSIFLKASIE 463
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 185.267 bits (469), Expect = 1.564e-50 Identity = 142/550 (25.82%), Postives = 247/550 (44.91%), Query Frame = 3
Query: 312 MPEKYNYTENFRNSQSRSIFFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNHSET-CQYRMKQCDL--CQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGD--KVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQH-------QTFLMGEIVQLRTENNNLKHSLESTNQSL---------HEE---------LQLVKGIN------KDLLKIVEKLQKQLTENESIILNIKSEMEKQKQL-------------IASPSINNENQINLV--------------------NGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
+PE+ Y E F + + +KC C+ V P QTECG RFC C+ +++++ C C+ I ++K +D +E+ ++ C NE C E+ L L H ++ CQ+ C C++ K H+ + C+ R C C+ Q+ + + H +++ C + CP CS + + HL EC N+ C F GCT + T +I H + QH +L ++ L+ E++ S++ + + H+E +QL + I KDL K + L++ E + + N +S + QL + IN +Q+ V NG L+W I + +++ +A G + + S+PFY+ GY+M ++Y NGDG GK +LS++F+I++GEYD + WPF+QKVSL ++ +R+++ KPD N + + KP N+ +G P F+ + +L + Y+ +I + + V TS
Sbjct: 28 VPEQGGYKERFL-------------KPVEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNITKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQ-KHEDVD------CPSVVISCPHMCSVKSLLRSELNAHLLECVNAPSTCSFKRYGCTFKGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIRNLRQTGDEADGMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTS 556
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925]) HSP 1 Score: 179.104 bits (453), Expect = 1.655e-48 Identity = 137/499 (27.45%), Postives = 230/499 (46.09%), Query Frame = 3
Query: 390 QLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNC--DLE-INRNKFIRDKAVEKEIFNHKIKCPNE-RCDEIFLLKELKNHSETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLR------TENNNLK-----------------------------HSLEST-------NQSLHEELQLVKGINKD--------LLKIVEKLQKQLTENESI---ILNIKSEMEKQKQLIASPSI---NNENQINLV-----NGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSEL 1685
QL +KC+ C V P QT CG RFC CI N I S + P C D+E I ++ +D ++E+ N + C N CD +L + H C Y M C D C K + H+ C+ R C C+Q M+ N HE N++ I + HL ECP +++ C FSN GC ++ +H + H +++ ++L +N +LK +SL ST ++S+ E Q+++ ++K+ +L +E +++L+ E+ I N+ + +K L+++ + +NE + LV NG+L+W I + +K +A G V I S+ FY+ GYR+ + Y NGDG GK +LS+YF++++GE+D ++WPF+QKV+L +L + +IT + D N + + +P + N+ +G P F ++L
Sbjct: 37 QLQDRYKCASCHLVLHNPHQTGCGHRFCEKCISNLIELSET--PQCPIDMENIKSHEIFKDNCCKREVLNLLVYCKNSPACDVKVMLGRYQEHLGQCLYEMTLCSNDGCHDQMIRKELKGHLESECKLRQEACIYCKQTMSFN-HENNYKKIFFSFQ---------------------LDKHLCECPEAELQCTFSNYGCNVMVKRGKVKEHEDTFLRDHMLYVLNRNMKLEEQVLSVLQNLDLKEHQIQQLSDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSMWLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLSTLEAYKDRIDNLDGQFKKHDVLLSNHKMQMTSNEERFRLVEGTSYNGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRADPNSSSFKRPDSEMNIASGCPRFASHAQL 511
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925]) HSP 1 Score: 177.178 bits (448), Expect = 8.264e-48 Identity = 138/496 (27.82%), Postives = 228/496 (45.97%), Query Frame = 3
Query: 390 QLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNC--DLE-INRNKFIRDKAVEKEIFNHKIKCPNE-RCDEIFLLKELKNHSETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKM----HLKECPNSQINCPFSNVGCTTRATVNEINKH-LEIESFQHQTFLMG---------------------------EIVQLRTENNNLKHSLEST-------NQSLHEELQLVKGINKD--------LLKIVEKLQKQLTENESI---ILNIKSEMEKQKQLIASPSI---NNENQINLV-----NGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSEL 1685
QL +KC+ C V P QT CG RFC CI N I S + P C D+E I ++ +D ++E+ N + C N CD +L + H C Y M C D C K + H+ C+ R C C+Q M+ LC +D +N K+ HL ECP +++ C FSN GC + ++ H L + +F + ++G + Q N N SL ST ++S+ E Q+++ ++K+ +L +E +++L+ E+ I N+ + +K L+++ + +NE + LV NG+L+W I + +K +A G V I S+ FY+ GYR+ + Y NGDG GK +LS+YF++++GE+D ++WPF+QKV+L +L + +IT + D N + + +P + N+ +G P F ++L
Sbjct: 37 QLQDRYKCASCHLVLHNPHQTGCGHRFCEKCISNLIELSET--PQCPIDMENIKSHEIFKDNCCKREVLNLLVYCKNSPACDVKVMLGRYQEHLGQCLYEMTLCSNDGCHDQMIRKELKGHLESECKLRQEACIYCKQTMS-----------------LCLACLDYMFSCRNNYKKIFFSFQLDKHLCECPEAELQCTFSNYGCNVMVLYHSLSVHFLYLCTFTSVSQVLGLQQNLDLKEHQIQQLSDTVKWCEKECHQFGQFTGSNGN---SLSSTKTLASYIDKSMWLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLSTLEAYKDRIDNLDGQFKKHDVLLSNHKMQMTSNEERFRLVEGTSYNGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRADPNSSSFKRPDSEMNIASGCPRFASHAQL 510
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 162.54 bits (410), Expect = 1.320e-42 Identity = 132/530 (24.91%), Postives = 237/530 (44.72%), Query Frame = 3
Query: 312 MPEKYNYTENFRNSQSRSIFFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNHSET-CQYRMKQCDL--CQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLE--IESFQHQT--------FLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGIN---KDLLKIVEKLQKQLTENESIILNIKSEMEKQKQL-------------IASPSINNENQINLV--------------------NGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
+PE+ Y E F + + +KC C+ V P QTECG RFC C+ +++++ C C+ I ++K +D +E+ ++ C NE C E+ L L H ++ CQ+ C C++ K H+ + C+ R C C+ Q+ + + H +++ C + CP CS V + E N QI ++ + E + +LE + Q+++ L ++ E K L + + + ++++G KDL K + L++ E + + N +S + QL + IN +Q+ V NG L+W I + +++ +A G + + S+PFY+ GY+M ++Y NGDG GK +LS++F+I++GEYD + WPF+QKVSL ++ +R+++ KPD N + + KP N+ +G P F+ + +L + Y+ +I + + V TS
Sbjct: 28 VPEQGGYKERFL-------------KPVEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNITKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQ-KHEDVD------CPSVVISCPHMCS-----VKSLLRSEGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIRNLRQTGDEADGMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTS 531
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925]) HSP 1 Score: 154.066 bits (388), Expect = 5.563e-40 Identity = 117/451 (25.94%), Postives = 207/451 (45.90%), Query Frame = 3
Query: 537 INRNKFI---RDKAVEKEIFNHKIKCPNE-RCDEIFLLKELKNHSETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCS-NGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLR------TENNNLK-----------------------------HSLEST-------NQSLHEELQLVKGINKD--------LLKIVEKLQKQLTENESI---ILNIKSEMEKQKQLIASPSI---NNENQINLV-----NGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSEL 1685
I+ N F +D ++E+ N + C N CD +L + H C Y M C D C K + H+ C+ R C C+Q M S N+ + + C + CP C + + HL ECP +++ C FSN GC ++ +H + H +++ ++L +N +LK +SL ST ++S+ E Q+++ ++K+ +L +E +++L+ E+ I N+ + +K L+++ + +NE + LV NG+L+W I + +K +A G V I S+ FY+ GYR+ + Y NGDG GK +LS+YF++++GE+D ++WPF+QKV+L +L + +IT + D N + + +P + N+ +G P F ++L
Sbjct: 17 ISHNNFFQIFKDNCCKREVLNLLVYCKNSPACDVKVMLGRYQEHLGQCLYEMTLCSNDGCHDQMIRKELKGHLESECKLRQEACIYCKQTMAS-------INLTIHVGLYCQLYPVPCPNACPVTCPRAELDKHLCECPEAELQCTFSNYGCNVMVKRGKVKEHEDTFLRDHMLYVLNRNMKLEEQVLGLQQNLDLKEHQIQQLSDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSMWLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLSTLEAYKDRIDNLDGQFKKHDVLLSNHKMQMTSNEERFRLVEGTSYNGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRADPNSSSFKRPDSEMNIASGCPRFASHAQL 460
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 186.037 bits (471), Expect = 5.655e-51 Identity = 144/552 (26.09%), Postives = 244/552 (44.20%), Query Frame = 3
Query: 312 MPEKYNYTENFRNSQSRSIFFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNHSET-CQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGD--KVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTN---QSLHEE----------------------LQLVKGINKDLLKI-----------------------VEKLQKQLTENESIILN----------IKSEMEKQKQLIASPSINNEN--------QINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
+PE+ Y E F + + +KC C+ V P QTECG RFC +C+ +++S+ C C I ++K +D ++EI ++ C NE C E L L H + CQ+ C C++ K H+ + C+ R TC C+ Q + ++ D C + CP +CS + + HL EC N+ C F GC + T +I H + QH L L + + L++ N QSLH + L L + I+ K+ VE LQ ++TE ES+ + ++S++ + Q+++ I + + NG L+W I + +++ +A G + + S+PFY+ GY+M ++Y NGDG GK +LS++F+I++GEYD + WPF+QKV+L ++ S+R+++ KPD N + + KP N+ +G P F+ + +L + Y+ +I + + V TS
Sbjct: 32 VPEQGGYKEKFVKT-------------VEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQ-------VPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTS 562
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548]) HSP 1 Score: 183.341 bits (464), Expect = 4.042e-50 Identity = 133/518 (25.68%), Postives = 227/518 (43.82%), Query Frame = 3
Query: 390 QLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYIN-NSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER-CDEIFLLKELKNHSETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSN---DHEINHRNIEMGIDNLCDKWIDVCPQRCSNG-DKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGIN-------------------------------KDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIAS---------PSINNENQINL-------------------VNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLD-YLHGTSIKLAIKV 1739
QL +KC+ C +V P QT CG RFC CI + NS CP I + +D ++E+ N + C N C+ +L ++H + C ++ C + C++ K ++H++ C R C C++ + DHE +N C + CP RC + + HL CP ++ +CPF + GCT + + +H H ++ + QL N L SLE + + + N + LL+IV + +L + S++ + S ++ QL AS + ++ IN+ +G+L+W + + R K +A G+ V + S+PFY+ R GYR+ + Y NGDG GK +LS+YF++++GE+D + WPFRQ+V+L +L + +I K D N + + +P N+ +G P F+ S L S + Y+ ++ L + V
Sbjct: 38 QLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQEVFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVKEHLSAYCRFREEKCLYCKRDIVVTNLQDHE----------ENSCPAYPVSCPNRCVQTIPRARVNEHLTVCPEAEQDCPFKHYGCTVKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRVNALLSSLERKKKMAAADSAIQHATNPMSRFQDIFSFLYRKALTSHTDKSAWLEAQVRQLLQIVNQQPSRL-DLRSLVDAVDSVKQRITQLEASDQRLVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAV 544
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548]) HSP 1 Score: 183.341 bits (464), Expect = 4.042e-50 Identity = 133/518 (25.68%), Postives = 227/518 (43.82%), Query Frame = 3
Query: 390 QLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYIN-NSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER-CDEIFLLKELKNHSETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSN---DHEINHRNIEMGIDNLCDKWIDVCPQRCSNG-DKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGIN-------------------------------KDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIAS---------PSINNENQINL-------------------VNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLD-YLHGTSIKLAIKV 1739
QL +KC+ C +V P QT CG RFC CI + NS CP I + +D ++E+ N + C N C+ +L ++H + C ++ C + C++ K ++H++ C R C C++ + DHE +N C + CP RC + + HL CP ++ +CPF + GCT + + +H H ++ + QL N L SLE + + + N + LL+IV + +L + S++ + S ++ QL AS + ++ IN+ +G+L+W + + R K +A G+ V + S+PFY+ R GYR+ + Y NGDG GK +LS+YF++++GE+D + WPFRQ+V+L +L + +I K D N + + +P N+ +G P F+ S L S + Y+ ++ L + V
Sbjct: 38 QLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQEVFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVKEHLSAYCRFREEKCLYCKRDIVVTNLQDHE----------ENSCPAYPVSCPNRCVQTIPRARVNEHLTVCPEAEQDCPFKHYGCTVKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRVNALLSSLERKKKMAAADSAIQHATNPMSRFQDIFSFLYRKALTSHTDKSAWLEAQVRQLLQIVNQQPSRL-DLRSLVDAVDSVKQRITQLEASDQRLVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAV 544
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 174.481 bits (441), Expect = 3.121e-47 Identity = 112/477 (23.48%), Postives = 222/477 (46.54%), Query Frame = 3
Query: 390 QLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLE---------INRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKN-HSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKM-----HLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKH---SLESTNQSLHEELQLVKGI----NKDLLKIV---EKLQKQLTENESIILNIKSEMEKQKQLIASPSIN--------NENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSI 1721
+L + CS CKN+ P Q +CG R+C C+ + +++ +C C E + + D A +E+ + CPN+ C LKE ++ H C + + +C C+ L + KE H + C +R ++C C+ + D E+++ +C K+ P C K I H++ C ++ C F VGC+ + H +H L+ ++ + L L Q L +++ + I N+++ ++ E +Q ++ I + +++++ ++ I + +E +++ +G +W I + +K +A +G I S FY+ R GY+M L++Y NGDG G+ +LS++F++++G D + WPF QKV+L +L + R+++ +PD + + +P+++ N+ +G P F +S++ Y+ +I
Sbjct: 27 RLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHY--------EVCPKF----PLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNN-REHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAI 490
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 167.162 bits (422), Expect = 1.286e-44 Identity = 112/484 (23.14%), Postives = 222/484 (45.87%), Query Frame = 3
Query: 390 QLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYI-------NNSNSSCPNCDLE---------INRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKN-HSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKM-----HLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKH---SLESTNQSLHEELQLVKGI----NKDLLKIV---EKLQKQLTENESIILNIKSEMEKQKQLIASPSIN--------NENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSI 1721
+L + CS CKN+ P Q +CG R+C C+ + + ++ +C C E + + D A +E+ + CPN+ C LKE ++ H C + + +C C+ L + KE H + C +R ++C C+ + D E+++ +C K+ P C K I H++ C ++ C F VGC+ + H +H L+ ++ + L L Q L +++ + I N+++ ++ E +Q ++ I + +++++ ++ I + +E +++ +G +W I + +K +A +G I S FY+ R GY+M L++Y NGDG G+ +LS++F++++G D + WPF QKV+L +L + R+++ +PD + + +P+++ N+ +G P F +S++ Y+ +I
Sbjct: 27 RLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILRCASILSSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHY--------EVCPKF----PLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNN-REHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAI 497
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q60803|TRAF3_MOUSE (TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN=Traf3 PE=1 SV=2) HSP 1 Score: 186.037 bits (471), Expect = 3.955e-50 Identity = 144/552 (26.09%), Postives = 244/552 (44.20%), Query Frame = 3
Query: 312 MPEKYNYTENFRNSQSRSIFFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNHSET-CQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGD--KVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTN---QSLHEE----------------------LQLVKGINKDLLKI-----------------------VEKLQKQLTENESIILN----------IKSEMEKQKQLIASPSINNEN--------QINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
+PE+ Y E F + + +KC C+ V P QTECG RFC +C+ +++S+ C C I ++K +D ++EI ++ C NE C E L L H + CQ+ C C++ K H+ + C+ R TC C+ Q + ++ D C + CP +CS + + HL EC N+ C F GC + T +I H + QH L L + + L++ N QSLH + L L + I+ K+ VE LQ ++TE ES+ + ++S++ + Q+++ I + + NG L+W I + +++ +A G + + S+PFY+ GY+M ++Y NGDG GK +LS++F+I++GEYD + WPF+QKV+L ++ S+R+++ KPD N + + KP N+ +G P F+ + +L + Y+ +I + + V TS
Sbjct: 32 VPEQGGYKEKFVKT-------------VEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQ-------VPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTS 562
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q13114|TRAF3_HUMAN (TNF receptor-associated factor 3 OS=Homo sapiens OX=9606 GN=TRAF3 PE=1 SV=2) HSP 1 Score: 185.652 bits (470), Expect = 6.183e-50 Identity = 146/555 (26.31%), Postives = 242/555 (43.60%), Query Frame = 3
Query: 312 MPEKYNYTENFRNSQSRSIFFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNH-SETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQ---MTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGD--KVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTN---QSLHEE----------------------LQLVKGINKDLLKI-----------------------VEKLQKQLTENESIILN----------IKSEMEKQKQLIASPSINNEN--------QINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
+PE+ Y E F + + +KC C V P QTECG RFC +C+ +++S+ C C I ++K +D ++EI +I C NE C E +L L H C + C C++ K H+ + C+ R TC C+ Q + HE D C + CP +CS + + HL EC N+ C F GC + T +I H + QH L L + + L++ N QSLH + L L + I+ K+ VE LQ ++TE ES+ + ++S++ + Q+++ I + + NG L+W I + +++ +A G + + S+PFY+ GY+M ++Y NGDG GK +LS++F+I++GEYD + WPF+QKV+L ++ S+R+++ KPD N + + KP N+ +G P F+ + +L + Y+ +I + + V TS
Sbjct: 33 VPEQGGYKEKFVKT-------------VEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHE----------DTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTS 563
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P70191|TRAF5_MOUSE (TNF receptor-associated factor 5 OS=Mus musculus OX=10090 GN=Traf5 PE=1 SV=1) HSP 1 Score: 181.8 bits (460), Expect = 1.345e-48 Identity = 129/523 (24.67%), Postives = 226/523 (43.21%), Query Frame = 3
Query: 390 QLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYIN-NSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNE-RCDEIFLLKELKNHSETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSN---DHEINHRNIEMGIDNLCDKWIDVCPQRCSNG-DKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQK-----------------------------QLTENESIILNIKS-------------EMEKQKQ---LIASPSINNENQINLVNGEL-------------------VWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLD-YLHGTSIKLAIKV 1739
QL +KC+ C +V P QT CG RFC CI + NS CP I + +D ++E+ N + C N C+ +L ++H + C ++ C + C++ K ++H++ C R C C++ + DHE +N C + CP RC + + HL CP ++ +CPF + GCT + + +H H ++ + QL ++L SLE + + + VK K+L + + + Q+ + L+++S ++E Q L+ + ++ IN+ +L +W + + R K +A G+ V + S+PFY+ R GYR+ + Y NGDG GK +LS+YF++++GE+D + WPFRQ+V+L +L + +I K D N + + +P N+ +G P F+ S L S + Y+ ++ L + V
Sbjct: 38 QLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQEVFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVKEHLSAYCRFREEKCLYCKRDIVVTNLQDHE----------ENSCPAYPVSCPNRCVQTIPRARVNEHLTVCPEAEQDCPFKHYGCTVKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRISDLYQSLEQKESKIQQLAETVKKFEKELKQFTQMFGRNGTFLSNVQALTSHTDKSAWLEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRITQLEASDQRLVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAV 550
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|O00463|TRAF5_HUMAN (TNF receptor-associated factor 5 OS=Homo sapiens OX=9606 GN=TRAF5 PE=1 SV=2) HSP 1 Score: 181.03 bits (458), Expect = 2.605e-48 Identity = 138/526 (26.24%), Postives = 249/526 (47.34%), Query Frame = 3
Query: 390 QLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYIN-NSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNE-RCDEIFLLKELKNHSETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKM----HLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLE---STNQSLHEEL------------------------------------------QLVKGIN--------KDLLKIVEKLQKQLT---ENESIILNIKSEMEKQKQLI---ASPSINNENQINLV-----NGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLD-YLHGTSIKLAIKVQTS 1748
+L +KC+ C +V P QT CG RFC +CI + N+ CP I + +D ++E+ N + C N C+ +L ++H + C ++ QC + C++ K ++H++ C+ R C C++ + IN +N E +NLC ++ CP C+ K+++K HL CP ++ +CPF + GC + +H +H ++ + VQL + ++L SLE S Q L E + QL++ +N + L++ V+ +++++T N+ + ++ E K I + NE + L+ NG+L+W + + + K +A G+ V I S+ FY+ R GYR+ + Y NGDG G+ +LS+YF++++GE+D + WPFRQ+V+L +L +S ++NI KPD N + + +P N+ +G P F+ S L + + Y+ ++ L + V +
Sbjct: 38 RLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVV----INLQNHE---ENLCPEYPVFCPNNCA---KIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLL-DQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDLT 552
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P39429|TRAF2_MOUSE (TNF receptor-associated factor 2 OS=Mus musculus OX=10090 GN=Traf2 PE=1 SV=1) HSP 1 Score: 174.481 bits (441), Expect = 2.183e-46 Identity = 112/477 (23.48%), Postives = 222/477 (46.54%), Query Frame = 3
Query: 390 QLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLE---------INRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKN-HSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKM-----HLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKH---SLESTNQSLHEELQLVKGI----NKDLLKIV---EKLQKQLTENESIILNIKSEMEKQKQLIASPSIN--------NENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSI 1721
+L + CS CKN+ P Q +CG R+C C+ + +++ +C C E + + D A +E+ + CPN+ C LKE ++ H C + + +C C+ L + KE H + C +R ++C C+ + D E+++ +C K+ P C K I H++ C ++ C F VGC+ + H +H L+ ++ + L L Q L +++ + I N+++ ++ E +Q ++ I + +++++ ++ I + +E +++ +G +W I + +K +A +G I S FY+ R GY+M L++Y NGDG G+ +LS++F++++G D + WPF QKV+L +L + R+++ +PD + + +P+++ N+ +G P F +S++ Y+ +I
Sbjct: 27 RLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHY--------EVCPKF----PLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNN-REHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAI 490
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1D122 (TRAF-5 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 325.865 bits (834), Expect = 2.262e-101 Identity = 170/469 (36.25%), Postives = 264/469 (56.29%), Query Frame = 3
Query: 342 FRNSQSRSIFFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNC-DLEINRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEME--KQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKV 1739
++ QS +F + R LS C +CK + EP Q++CGCRFC CIE +I+ CP C D I + IRDKA+EKEI +++CP E C E + +E H C Y + +C+ C + Y KE H E C +V CDDC ++M D + H+N + ++LC+KW+ CP +C+ V +K H C CP ++GC + E+ HL+ HQ ++ EI LR + +K L + ++ + ++ INKD V++L++++ ++ SE+ K P + E + ++ W I++IR+KI +AK G ++ISE FY RPGY M LK++ NGDGR +KYLS +F+I +GEYD +I WPF+ +V LSILS+ ++++I + MKP+NN CYG+P N+GAGQP+ ++LSE+L YLH ++KL + +
Sbjct: 1 MKSVQSVPVFLDDL-RTLS-RCSCGICKQIMFEPTQSQCGCRFCSKCIEEFISKEKRKCPICTDQNIEKVSLIRDKAIEKEIMRMRVQCPQEGCGENIMYREWGGHERACVYGVNECEKCGEEYVRSRKEDHEREECGESVVKCDDCGKEMRREDLKNVHKNYDGDEESLCEKWMCKCPYQCTEEQYVNMKEHASSCRERCTPCPLKDIGCEVKGPQGELKVHLKEAVGLHQILMLKEIKDLREQKEEMKKMLREKEEDHRKKYEELREINKDNETSVKELKEKVDHITKYSESLLSELTTYKSNSHPKEPLTDIEASLR----DVTWSIKDIRKKIQEAKCGGNNELISECFYVFRPGYNMSLKVFLNGDGRATNKYLSTFFVINKGEYDSQISWPFKSRVLLSILSNNLSKEDIVVRMKPNNNDQCYGRPSGRCNLGAGQPDLVELSEILNKDYYLHHGALKLRLTL 463
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1DF65 (TRAF-2 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 312.768 bits (800), Expect = 2.879e-96 Identity = 173/476 (36.34%), Postives = 260/476 (54.62%), Query Frame = 3
Query: 321 KYNYTENFRNSQSRSIFFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINR--NKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQ 1742
KY+ + + RS F Q C C V IEP QT+CGCR C NC+E + S CP C+ +N N DKA+EKEI I C N+ C+ +K+L NH ETC+Y K+C C + Y K ++H C+ I TC+DC +++ D E H+N+ IDN+C KW D+CP +CS V IK HL C + C + +GC E+ +H +E+ H LM + LR E+ +L S+ N+ E++ +K LL +E L+ +L + +S+ +++E +A S++ + GE W +ENI +K++DAK G QI+SE FYS PGYRM LKIYPNGDG YLSVYF++++G+YDD+I WPF +S+ +++ ++ LNM+P+ N CYG+P N+ AGQP+F+ +L+ D++ +I L + V+
Sbjct: 2 KYSCLAVLKVIKDRSKLFYFECEQQKQRISCVKCHQVLIEPYQTQCGCRLCSNCLEECSKDEESHCPGCNETMNSPSNYSKHDKAIEKEILELNIICTNKGCEYTCKVKDLDNHLETCEYIEKRCTACNESYPRKELKKHEEFTCKMIITTCEDCGLELSKGDLEKKHKNVNELIDNVCSKWRDICPFKCSEDTLVNIKDHLLTCERRPVECSLNEMGCRKVLPREEMREHFNLEANYHTVLLMDALFLLRKEHQDLSVSVSVQNERNSAEIKELKEKLSSLLTEIEDLKTKLKQFQSMYEKLENERN-----LAKCSLSETKE---RYGEYTWKVENIMEKVNDAKKGVNTQILSESFYSSNPGYRMCLKIYPNGDGSAFGNYLSVYFVLMKGKYDDQIQWPFNSIISIRLVNIARRGEDRVLNMRPNINDQCYGRPKEEHNLAAGQPKFVSHLQLVNEDDFIKDGAIILRVNVK 469
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1DBK6 (TRAF-4 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 241.891 bits (616), Expect = 1.852e-69 Identity = 144/439 (32.80%), Postives = 222/439 (50.57%), Query Frame = 3
Query: 381 WNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSC----PNCDLEINRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSEL 1685
W ++ N KC +C+++ ++ IQT+CGCR+C CI+NY+ N C +C I +I D+A KEI K+KC E C LK +K H + C+YR + C LC Y K + H+ C R V C C+ +T ++ +H E +LC K+ +CP C+ KV + H K C N + CP C +++ +HL S++H ++ E+ +L +N KH E N L EE QL+K +E ++ L +N I S+ N+ NG+ +W I++ + +A G I+SE FY+ GY+M +KIYP GDG GK +LS++F+I++G+YDD + WPF+ KV ++I S N++ KPD CY +P N+ +G P+FI SEL
Sbjct: 21 WRFTINDNLKCVMCQDILLDAIQTDCGCRYCKECIDNYLENGEKECVAEYEDCRSVIT--SYIYDRATNKEISLLKVKCLYEGCVFEDTLKSIKGHLDFCEYRNEMCSLCGMEYIIKEESNHLANECLLREVLCQYCRTLLTFKEYNESHLCFES--RDLCGKYEAICPYGCTGESKVNLLHHRKSCENKPLECPLHVFDCKQLIPKDQMTEHLNTSSYEHTLTIVTELRKLEKQN---KHMEERMN-ILIEENQLLKAT-------LEVMKLDLPKNSGSISR-------------DTSLKRANKTIFRNGKYMWKIKSFSKLRENAMRGKNPTILSEAFYTSDFGYKMCMKIYPCGDGVGKGTHLSIFFVIMKGDYDDILPWPFKNKVIITIFDDFSKSTNLSDTFKPDPKSICYQRPEEEYNIASGSPKFISFSEL 431
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: D5JG60 (TNF receptor-associated factor-2-like protein B OS=Dugesia japonica OX=6161 GN=TRAF-2B PE=2 SV=1) HSP 1 Score: 240.35 bits (612), Expect = 6.728e-69 Identity = 140/435 (32.18%), Postives = 230/435 (52.87%), Query Frame = 3
Query: 393 LSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKNHSETCQYRMKQCDLC-QQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEK---QKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSEL 1685
+S N KC +C + +E +QT+CGCR+C C++ Y + C D + I D AV +EI +KC C+ LLK++ +H ++C ++ C C ++L + + KE H + C R+V+C C ++M ++ H N+ + LC K + CP +C NG +V + H K C + C FS +GC T ++ KH ES QH LM EI+ ++ + + LK +K + ++LKI + ++ +S IL+ +EK S ++E + NG +W IE + +A+ GN++ I S+ FY+ GY+M +KIYP GDG GK +LSV+F +++GE+DD + WPF+ KV+L+IL K+ + + KPD CY +P ++ N+ +G P+FI S+L
Sbjct: 24 ISDNLKCIICSQLLLEALQTDCGCRYCKECLKEYQAKGKTKCLT-DGCGDLGNIIPDNAVNREIGKLTVKCLFPGCEHSELLKDIGDHLDSCIHQTINCKSCNEELTKIELKE-HTEKKCPMRLVSCTHCGEEMEYSNLTELHLNVH--TEKLCAKLVGKCPYKCDNGKEVNLLDHRKSCSKKPVTCLFSEIGCNRVMTKEDLIKHNNEESLQHSRLLMKEIITMKNDISELK----------------MKTLEFNILKI------EFSKFQSEILDKIKSLEKIPRHTSPSTSSVRSSEEKTVYRNGVFIWKIERFSELKSEAERGNRISITSDYFYTKEFGYKMSMKIYPAGDGVGKGTHLSVFFTLMRGEFDDLLQWPFKNKVTLTILDQKNKTNDHSDTFKPDVRSTCYQQPTDDYNIASGSPKFITFSQL 432
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: D5JG59 (TNF receptor-associated factor-2-like protein A OS=Dugesia japonica OX=6161 GN=TRAF-2A PE=2 SV=1) HSP 1 Score: 218.009 bits (554), Expect = 1.606e-61 Identity = 129/365 (35.34%), Postives = 197/365 (53.97%), Query Frame = 3
Query: 654 HSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTT-RATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQT 1745
H E+C R C+ C + K K H + CE R+V CD C M S D I H N + D LC K++ +C C+ KV +K HLK CPN ++ CPF C + T ++ KHL+ E F H + L+ ++ L ++ +L+ L NQ L I K+L + + K+ +E+ I E++K+ + +I+N+N I N +W + + DA+SG +V + S+ FY+ GY+M L++YP GDG GK +LSV+F I++GE+DD + WPF+QKV+LSIL +S + + KPD ACY KP + N+ +G P+FI LS ++ + Y +I L I V T
Sbjct: 4 HIESCDLREITCEKCGIKFGAKEKANHDKDKCEMRMVNCDYCGITMKSKDLNIIHLNPDR--DELCSKYVGICSNNCNETRKVNLKDHLKICPNKKLECPFHQFDCKIDKMTKEKLMKHLDEEYFNHTSSLINKVKDLESKIIDLESELH--NQIL---------ITKELFE----MNKKSSESRLKIEKTIEELKKKAPATSIQTIDNKNVI-FRNASFIWKFTDFEVRRVDAESGGRVSVTSDAFYTSEFGYKMCLRVYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSILDQESGSKPHSDTFKPDARSACYQKPTDECNIASGFPKFILLSLIMNNSIYCKNDTIFLKIAVDT 350
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:103028261]) HSP 1 Score: 178.718 bits (452), Expect = 1.068e-48 Identity = 128/497 (25.75%), Postives = 222/497 (44.67%), Query Frame = 3
Query: 402 NFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLE---------INRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELK-NHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKM-----HLKECPNSQINCPFSNVGCTTRATVNEINKHLEIES--FQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQ-----------------------------LVKGINKDLLKIV---EKLQKQLTENESIILNIKSEME--------KQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSI 1721
++C CK V +P Q +CG RFC C + ++ C C E ++ + D A +EI KCPN+ C LKE + H C++ +C+ CQ + K++H CE R + C C+ + D + + D +C K+ P +C + K I H K C S+ C FS +GC RA V+ +H +S +H ++ + +R ++ E + L+ + +V +N+++ + V E L +Q ++ I N+ +++ + QL S E Q +G VW I + ++ DA +G + S FYS + GY+M L++Y NGDG G+ +LS++F++++G+YD + WPF QKV+L +L ++ R++I +PD + + +PI+ N+ +G P F L++L YL +I
Sbjct: 39 KYQCQQCKGVLRKPFQAQCGHRFCVFCFKQLTSSGPIPCEACRAEGIFEMEHSMLSITEAFPDNAARREIDGLPAKCPNDGCSWNGTLKEYEVQHEGRCEFERVKCEACQMMILLSDKDRHNERECEARTLNCKYCKVTFSFKDIKAH--------DEICQKF----PMQCKDCGKKKIPREKFAEHSKSCAKSKSACQFSEIGC--RAVVDNGKQHEHEQSSIIEHLRLMLAVLSTVRVRSDGPGEWQEDSGLGLYRGPEDAAPPGAHAAAHNAAGGPGVQQKMTALENIVCVLNREVERTVLRLEALTRQQQLDQEKIENLSNKVRQLERTLTMRDLQLAESEQALRELQFCTYDGVFVWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLL-DQNNREHIIDAFRPDISSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTI 520
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf5 (TNF receptor-associated factor 5 [Source:NCBI gene;Acc:103031120]) HSP 1 Score: 166.392 bits (420), Expect = 3.990e-44 Identity = 137/564 (24.29%), Postives = 235/564 (41.67%), Query Frame = 3
Query: 312 MPEKYNYTENFRNSQSRSIFFINW-------NRQLSL------NFKCSLCKNVFIEPIQTECGCRFCYNCIENYI-NNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNE-RCDEIFLLKELKNHSETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQ-----QMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKV-VIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLM----------------------GEIVQLRTENNNLKH-------SLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINL--------------------------------VNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTST 1751
M + N F+ SQ S +W R LS F C C V P QT CG FC CI + NN S CP + I + +D ++E+ N ++ C N C + L L++H ++CQY QC C + K H C R C CQ+ Q+T DHE C + CP +C + K +K H ECP + +C + GCT R ++ H + E F H L+ GE+ + +NLK ++ + +S+ E+ +LV + ++L + + L+ LT+ E ++++++ ++ ++ +A E+ L +G+L+W + + +K + N S PFY+ GY++ ++Y G+G + +LS+Y M+++G++D + WPFRQ V+L++L R +++L+ PD + +P + +N G P FI ++L + + L IKV+ T
Sbjct: 1 MAAEENECPKFQFSQQSSGLVRSWELESVLAGRTLSFVVKLDDQFVCPACGGVVFNPHQTGCGHIFCSPCIRVILENNETSKCPFDGILIKPEEVFQDNCCKRELLNLEVFCTNSPACSQTIPLCNLQDHLKSCQYEALQCPNSSCTDILLRKNLPDHQRSHCSYRTELCRYCQKPYPVSQLT--DHE----------KTSCPEAEVQCPNKCIHLVKRHKLKDHADECPEQETDCIYKKYGCTVRNKRGQVKVHEQTE-FNHHVLLLLESNSKLIKQVDQLQQDFAAQQGELKERNLLVSNLKREVSKCDTTVSAMQRSVEEQRELVSSVKRELKDLRDVLEADLTKEE--LVSLRASLDSLREQVAMTQSLREHLGALGQTCQSHTRLLDIHVQQLQCSEQRFQQLESTSYDGKLIWKVHDYHRKKEAGTALN-----SPPFYTSHSGYKLSARVYLGGEGTARGTHLSLYVMLMRGDFDSLLPWPFRQNVTLAVLDQSGNRNHVSLSFTPDLASNNFRRPTSETNAALGFPRFITHADLEAPRNAAYVRDDTLFIKVKVDT 544
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252]) HSP 1 Score: 159.073 bits (401), Expect = 1.152e-41 Identity = 122/500 (24.40%), Postives = 217/500 (43.40%), Query Frame = 3
Query: 399 LNFKCSLCKNVFIEPIQTECGCRFCYNCIENYI-NNSNSSCPNC----------DLEINRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKNHSETCQYRMKQCDL-CQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSND-HEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQL----------VKGINKDLLKI------------VEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLV------------------------------------NGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSEL 1685
++F CS C NV E QT+CG R+C C+ + NN + C C + + + F D A+ KEI ++ C N+ C LK+ ++H C+Y + C++ C + K H+ + C TC C +T + + + ++ +K +E P + C FS +GCT + +++ +H E+ S L+ E+V R ++ E T Q +L L G N L + + LQ++L E+II + E+EK + + +N N +NL+ +G +W I ++ QK+ +A +G + S FY+ R G+++ +++Y GDG GK ++S++F+I++G+YD + WPF+QKV+ L ++ R+++ +PD A + +P++ NV +G P F LS+L
Sbjct: 25 VHFLCSSCNNVLNEAHQTQCGHRYCRACVMWLLRNNKDLICTKCKEDPGSESDSSMMLTLDHFFSDNAINKEIQELRVHCVNQGCGWRSTLKDFEDHQSQCEYALIPCNIGCGLMVLRKTLATHLEKGCPNNKTTCQVCCSALTPAELQSVTYFSL-------------------------FLKDSKQESPKRKETCVFSEIGCTFKGNPDKVREH-EVSSTSAHLHLLVEVV--RNVQMSVPPPPERTVQYPALDLTLNGGELETDSGDTGANDKALSLHDDQAELEVGQQLHALQQRLQIMENIITALNREVEKTQLTVVVLERDNHNNMNLIQHLEAVVAEQQQRLIRKDLQISSLQQSISAQQDVSYDGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTF-FLIDQNQREHVVDAFRPDLRSASFQRPVSEMNVASGCPLFFPLSKL 495
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252]) HSP 1 Score: 155.992 bits (393), Expect = 1.536e-40 Identity = 126/519 (24.28%), Postives = 219/519 (42.20%), Query Frame = 3
Query: 399 LNFKCSLCKNVFIEPIQTECGCRFCYNCIENYI-NNSNSSCPNC----------DLEINRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKNHSETCQYRMKQCDL-CQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVI-------KMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLV-----------------------KGINKDLLKI------------VEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLV------------------------------------NGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSEL 1685
++F CS C NV E QT+CG R+C C+ + NN + C C + + + F D A+ KEI ++ C N+ C LK+ ++H C+Y + C++ C + K H+ + C TC C +T + + CSNG + + K +E P + C FS +GCT + +++ +H E+ S L+ E+V R ++ E T Q +L L G N L + + LQ++L E+II + E+EK + + +N N +NL+ +G +W I ++ QK+ +A +G + S FY+ R G+++ +++Y GDG GK ++S++F+I++G+YD + WPF+QKV+ L ++ R+++ +PD A + +P++ NV +G P F LS+L
Sbjct: 25 VHFLCSSCNNVLNEAHQTQCGHRYCRACVMWLLRNNKDLICTKCKEDPGSESDSSMMLTLDHFFSDNAINKEIQELRVHCVNQGCGWRSTLKDFEDHQSQCEYALIPCNIGCGLMVLRKTLATHLEKGCPNNKTTCQVCCSALTPAELQ---------------------KHSCSNGTEKDLSKAEKRKKDSKQESPKRKETCVFSEIGCTFKGNPDKVREH-EVSSTSAHLHLLVEVV--RNVQMSVPPPPERTVQYPALDLHLQNQDMTPLPDITLNGGELETDSGDTGANDKALSLHDDQAELEVGQQLHALQQRLQIMENIITALNREVEKTQLTVVVLERDNHNNMNLIQHLEAVVAEQQQRLIRKDLQISSLQQSISAQQDVSYDGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTF-FLIDQNQREHVVDAFRPDLRSASFQRPVSEMNVASGCPLFFPLSKL 518
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:103024022]) HSP 1 Score: 151.754 bits (382), Expect = 1.890e-39 Identity = 125/510 (24.51%), Postives = 210/510 (41.18%), Query Frame = 3
Query: 405 FKCSLCKNVFIEPIQ-TECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKC--PNERCDEIFLLKELKNHSETCQYRMKQC-DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNI-----------------------------------------EMGIDNL------CDKWIDVCPQRCS--NGDKVVIKMHLKE-CPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSIL----SSKSARQNITLNMKPDNNVACYGKP------INNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQ 1742
F+C LC EP+Q + CG RFC C++ +++ CP L ++ K D +E++I I+C E C +K+L+ H TC + + C + C + +H+ C +R V C+ C + T E NH+ I E D + C ++ CP +C N + + H+KE C ++ + CPF + GC R I +HLE + H T + + + R E I+ ++ EME+ S+++ +G L+W + + +K+ +AK N + S PFY+ R GY++++ + NG+G G+ +LS+Y ++ GEYD+ + WPF KV+ SIL S S Q+IT PD N + KP ++ S +G G P+FI E + +Y+ +I L ++
Sbjct: 16 FQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCAVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAFE-NHQGICPQESVYCENKCGARMMRRLLAQHTMAECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLATHVKESCGSALVLCPFKDAGCKHRCPKLAIGRHLEETTKSHLTMMCSLVGRQRQE----------------------------------------------IIELRREMEEL-------SVSH-------DGVLIWKLNDYSRKLQEAKLHNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFAYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPSSSRNSLDESTLGFGYPKFISHDE-IRKRNYIRDNAIFLKASIE 463
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 132.88 bits (333), Expect = 1.356e-33 Identity = 108/435 (24.83%), Postives = 195/435 (44.83%), Query Frame = 3
Query: 513 SCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKE-LKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDH----EINHRNIEMGIDNLCDKWI------DVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEI-ESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKI--------VEKLQKQLTENESIILNIK---SEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
SC C+ ++ + + K E + I CPN +C+E + +E L +H C Y+ +C Q ++K Q + E + + H N+E+ + L + D+ R +K +I + N + C R + + L + ES Q T R +++ L+ L+ T +LHE V I + + + L L+ +++ + +EM+ + Q++ + S N G+LVW I + ++ DA SG + + S+PFY+ GYRM + Y NGDG G+ +LS++F++++GEYD + WPFRQ+V+L++L +AR+ ++ KPD + + +P ++ N+ +G P F+ L S YL +I + + V T
Sbjct: 77 SCRYCNQQVPLAE--KRKHYETRCPRYPIPCPN-KCEEQSIAREELVSHLGICPYKQAECFFSQFGCKYKGTLQGLKE------------HESGATQQHLSLVTARSANLELKVSMLQSQLAERANSADLLGTRVRELEKELISVGQTASKNESVLC------VVQRMLAVQTERLLRLQESMQGTT--------RRADHDALRGDLDGTAATLHELGTRVAAIEESGGSVTHSSTPTRLAALDSALSRHDTQLFAHDTRLAEMDLRFQVLETASYN---------GKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSDTFKPDPASSSFRRPTSDMNIASGCPLFVS-HVALESASYLQDDTIFIKVVVDTG 472 HSP 2 Score: 57.3806 bits (137), Expect = 5.624e-9 Identity = 47/223 (21.08%), Postives = 84/223 (37.67%), Query Frame = 3
Query: 588 NHKIKCPNERCDEIFLLKELKNH-SETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTC-DDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQ 1250
+ + CP+ C E L EL NH + C +R + C C Q K +H C R + C + C++Q + + ++H I CP Q C FS GC + T+ + +H + QH + + L + + L+ L S V+ + K+L+ + + K NES++ ++ + Q +
Sbjct: 44 HEAVNCPHAGCTERLLRGELVNHVALGCHFRTESCRYCNQQVPLAEKRKHYETRCPRYPIPCPNKCEEQSIAREELVSHLGI---------------------------------CPYKQAECFFSQFGCKYKGTLQGLKEHESGATQQHLSLVTARSANLELKVSMLQSQLAERANSADLLGTRVRELEKELISVGQTASK----NESVLCVVQRMLAVQTE 229
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 122.865 bits (307), Expect = 1.647e-30 Identity = 86/369 (23.31%), Postives = 159/369 (43.09%), Query Frame = 3
Query: 747 CERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGD--KVVIKMHLKECPNSQINCPFSNVGCTTR-ATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLE----------------------------STNQSLHEELQLVKGINKDL--LKIVEKLQKQLTENESIILNIKSEMEKQKQLIAS---PSINNEN-------------------------QINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFI 1670
C R C C +T + E +H+ C ++ CP C + + H+ C S C F +GCT + T + +H E H T ++ +L + L+ S+E S N L L+++ N+ L L + ++ ++ + ++ ++ + E+ + L A+ P E + +G+LVW I + ++ +A SG + + S+PFY+ GY+M + Y NGDG G+ +LS++F++++GEYD + WPFR++V+LS+L +AR++++ PD + +P + NV +G P F+
Sbjct: 29 CPHRAEFCKYCSAAVTCSLLERHHKEE-------CAQYPLPCPNNCEEHGIPRAELSQHMSACAMSTKLCGFHMLGCTFKQGTSESVREHEESAVRSHFTLVISRNSELELQCARLQCSIEDHTNMSEMLTQRVAQLEQDLSHWSTLTGSNNTRLGSTLEMLTQHNEQLQSLHVAQRAPQRDADTAALRRDMATLRERLRALEAALGNPGPCEERCHMHEQRLTMHDGLLDTAERRLQVLETAGYSGKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTFTPDPASGSFRRPDGDMNVASGCPLFV 390
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 120.939 bits (302), Expect = 4.163e-29 Identity = 106/503 (21.07%), Postives = 210/503 (41.75%), Query Frame = 3
Query: 369 FFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENY--INNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLK-ECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLR---------------------------TENNNLKHSLESTNQSLHE--------ELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSIN-NENQINLVNGELVWIIENIRQKI---------HDAKSGNQVQII-SEPFYSIRPGYRMRLKI-------YPNGDG------RGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSS-KSARQNITLNMKPDNNVACYGKP-INNSNVGAGQPEFIKLSEL 1685
+ ++ L ++C +C EP+QT CG RFC CI + + ++ CP + ++ + D ++EI + ++CPN+ C L+ L+ H C+Y C C+ + +H + C RRIVTC C ++M D + NH + +C + C + + HL+ +C +Q+ C FS +GC + + + H+ + H L + LR T +++ + S +Q + EL ++ I + L + V Q+ E + N + + + +L+ S E++ L G W +E + + D + ++ S FY+ PGYR+ L++ P G G+ +L+++ ++QG+YD + WPF+ ++ +S++ + ++T M D ++ + +P ++ + G G F+ ++ L
Sbjct: 51 YEADFEPPLESKYECPICLMALREPVQTPCGHRFCRACILHSMRLRDAGPKCPVDNAVLHEGQLFPDNFAKREILSLTVRCPNKPCGHRGELRALQEHQLRCEYAQVPCVRCEMPVCRRDLAKHEEQECMRRIVTCLHCCEKMAYKDSK-NH-------EQMCPLVVVNCKHCQQELIREQLGPHLEVDCQQAQVPCTFSPLGCEAQMVRSLLAAHMHEHTQVHMRLLANGLKILRIQVGQGAQPSSAAGSSAPPNSLSWLSSTSGGDVQTAGASRSQGSRDRAACDCAQELDRLREITRTLEERVVLQLHQIRELSAKTDNQQGLLAEATRLVRSLEARVAESESRLCAGIFTWRVERFSRLLPGGLASGFASDGMHPDAPAVMHSSGFYTGVPGYRLCLRLQVLSGREVPAGAASPSVLLAGRQPHLALFVHLLQGDYDHRLPWPFKGRIRISVVDQCERDSVHVTEMMDADPQLSAFQRPSVHRNPKGFGYMNFMDINTL 545
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008091.1 (pep scaffold:Pmarinus_7.0:GL477915:34322:50582:-1 gene:ENSPMAG00000007312.1 transcript:ENSPMAT00000008091.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 99.3673 bits (246), Expect = 1.238e-22 Identity = 97/419 (23.15%), Postives = 177/419 (42.24%), Query Frame = 3
Query: 405 FKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEIN-----RNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELK-NHSETCQYRMKQCDLCQQLYQFKFKE--QHMNELCERRIVTCDDCQQQMTSND---HEINHRNIEMGIDNLC-------DKWIDVCPQRCSNGDKVVIKMHLKE--CPNSQINCPFSNVGCTTRATVNEINKH----LEIE-SFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEK---------LQKQLTENESIILNIK------SEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQ--VQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQK 1535
F C C+ + + +QT CG RFC CI I + + SC + + N +F D A+ +E+ ++C +E C+ L E H E C + + C L E +H+ + C R V C C Q + H+++ R+ LC DKW H +E C ++ CP+S +GC R ++ H +E+ + + F ++ +N+KH + + +L + +++ K VE+ Q + +E+ L K S+ E ++ ++ E + NG +W I+++ ++ +A +G + QI S F++ R GYR+RL++ +G+ ++S Y M+ G YD + WP++ K
Sbjct: 3 FACGSCQGLLRDAVQTHCGHRFCKPCIARLITSVHRSCNDTLMNSNFLVYSPTQFFPDAALRREMGVLPVRCVSEGCEWRGRLLEYDVAHVERCDWVLVPCLLAGCALLLPRAELHRHVAQECSVRPVPCAACAQLLPYRQLQKHQLHCRSRRTRECKLCGQKSIPEDKW-----------------QHHEERRCMKNRDTCPYSPLGCLYRGHGESLHNHDKNSVEVHLAIVYDAFKKTFEQLIKGHADNIKHPPSARLVAAEAQLATMDRRVEEVAKRVERDVRVSEASTRQGNIDRDETARLQNKMARVEHSDQETERSILGLTRRLAELENTAYNGMFLWKIKHVINRLREAGNGAERPPQIDSPAFFTTRYGYRLRLRLCRSGE------HVSAYAMLGPGPYDATLAWPYQLK 398
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO49464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG36]) HSP 1 Score: 166.007 bits (419), Expect = 1.699e-44 Identity = 128/524 (24.43%), Postives = 226/524 (43.13%), Query Frame = 3
Query: 393 LSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNHSETCQYRMKQC--DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNL--CDKWIDVCPQRCSNG--DKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLM--------------GEIVQLRTENNNLKHSLESTNQSL---HEELQLVKGI-----------NKDLLKIVEKLQKQ-----LTENESIILNIKSEMEKQKQLIASPSI------------NNENQINL-------------------VNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
L ++C +C N P+QT CG RFC C+E + S CP E+ + +D +EI CPN + C+ + L+ L+ H C+Y+ QC CQ+ + E H+ E CE + C C Q++ + E D+L C+K VCP + G ++ C +++ C F+ GC + T + H ++ H L+ ++ Q+ E + + ++L ++ L+ +G ++L ++ E++Q Q + E + + I++E + + P NE+Q+ L +G +W I+ ++ + SG I S PFY R GY+ ++YPNGDG GK +LS++F++++GE+D + WPFRQKV+ +L +I +PD + + +P +N N+ +G P FI + L T Y+ ++ + I V T+
Sbjct: 15 LDPKYRCPVCGNALKHPVQTPCGHRFCEGCLEPILRGP-SKCPVDGEELKIDGVFKDVCCRREILCLACYCPNRQLGCEWMKDLQYLEEHRANCEYKGVQCHNPGCQEKVAKRDLEAHL-ERCEFKPSDCQYCLQRIPAASME----------DHLQTCEKHPVVCPHCGAEGICRDELLHHQTNICEQAELPCSFAKHGCHFKGTREALETHFRDQASVHVNLLLTATQNEEKARSEMAAKLSQMEKERAKQQEQMYEQREALAVANQNLRTYQGKLNVIERSVAEQRRELAELKERIQLQEVEAAIREQDRRLGMIENEASRGAAPSSGPGSMGGTMALERRQDRNEHQLALHDIQLAEHDLKLQMLEATSYDGTYIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLDQDRV-HDIGDTFRPDPTSSSFKRPTSNMNIASGCPLFISHTNLQTRA-YVRDDTMFIKIAVDTT 524
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO32849 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STV3]) HSP 1 Score: 152.525 bits (384), Expect = 3.372e-40 Identity = 106/457 (23.19%), Postives = 213/457 (46.61%), Query Frame = 3
Query: 411 CSLCKNVFIEPIQ-TECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNHSETCQYRMKQCD-LCQQLYQFKFKEQHMNELCERRIVTC---DDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHL-KECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILS---SKSARQNITLNMKPD---NNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKV 1739
C +C+++F+ P+Q ECG R C +C + + CP C +++ D+A E ++ +C N C ++ H C+Y CD C +Q +FK++H+++ C ++I++C DD + +H + I + N CDK + + + + H+ KECP +++ C F ++GC R + ++ KH++ E H + G +++ + + +N E E+E+I+ + S + +++ S +++W IE+ +K+ +AK+GN + S F + + GYR+ + NGDG+GK ++SV+ +++G +D + WPF +V+ +L+ + R+++ ++KP+ +N G+P N G +FIK E + S +++ ++ L + V
Sbjct: 55 CPVCEDIFVSPVQIKECGHRLCQHCYKTIWRSPEPKCPKCSGDLDDKIPDVDQAFENDMNELPCRCINHEWGCKVEVPFTQMITHKGECEYSDILCDNDCGAKFQRRFKQKHLDKDCPKKIISCPYCDDRHLRENKKEHLEDCLLIPLPCPNKCDKTLTI--------PRGQLDEHIEKECPRAKLMCEFESLGCQHRCSREKMAKHMKSEIIGHVKMIFGVVLEQKEKLDNHAQKFE--------------------------------EHETIMKQVDSRVGDLEKIAHS--------------QIIWRIEDYTRKLKEAKAGNAETLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFVSVLKGAFDALLKWPFHYRVTFFLLNQHENPEERKHVKFSIKPNPIPDNEPFLGRPRLEKNASFGGAKFIKHEE-IESGNFIKDDTVFLKVSV 456
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO48394 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJK8]) HSP 1 Score: 147.132 bits (370), Expect = 3.508e-38 Identity = 127/481 (26.40%), Postives = 209/481 (43.45%), Query Frame = 3
Query: 411 CSLCKNVFIEPIQTECGCRFCYNCIENYINNSN-SSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKNHSETCQYRMKQCDL--CQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLH-------EELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQ-----KQL-IASPSI-NNENQI---------NLVNGELVWIIENIRQKIHDA---------KSGNQVQ----------IISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVA----CYGKPINNSNVGAGQPEFIKLSELLTSLDYL 1706
C++C V EP+ T CG +C CIE + N +CP + ++ ++ DK ++ + + ++KC N C L++ + H + C ++ +C L C E+H N C R++ C C D E H +CP + + C FS +GCT + + ++H E H I + + ++L L+ Q L +E+ ++ + + ++ + + L++ I N E ++Q K+L IAS +I N +QI +G VW I N + K A K GN ++S PFY+ R GY+MRLK YPNG G GK +LS+ I++GEYD + WPFR+K++LS+++ ++ T+ + PD+ + +PI N NVG G FI E L S DY+
Sbjct: 30 CAICHMVVNEPVLTSCGHSYCKYCIEKWCNGKEVVTCPVDNEQLKPSQIFPDKKTDRIVLSLEVKCTNNPCRWKGELRQKQKHLKICSHKAVKCILEGCNVKVPRILMEKHTN-TCGWRLLHCKPCNLSYPKKDEETVQ--------------------------------HKDDCPLAFLPCRFSEIGCTFKGRESARDEHCESAVQTHLHIACETIRDNKEQISDLHKELDKVRQELQTKSCDHMKEVNAIREKHDEAIRDNKGQIEALSKEHGIASNTIHENKEQLDTLKKELGIASETIRKNRDQIAKLSTACKTQYTDGTFVWRICNYKDKYKKAVAFATNQEVKGGNSDSDDDISMAGDIMVSLPFYTSRYGYKMRLKAYPNGYGDGKGTHLSLSIRIMKGEYDAILEWPFRRKITLSLINQSEQWRSETVEIYPDDATPDKKHKFERPIENENVGCGYSCFISHME-LNSGDYI 476
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO38873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBN4]) HSP 1 Score: 138.658 bits (348), Expect = 3.046e-35 Identity = 120/467 (25.70%), Postives = 216/467 (46.25%), Query Frame = 3
Query: 411 CSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNE--RCDEIFLLKELKNHSETCQYRMKQC---DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEIN----KHLE-----IESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINK--DLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSI---NNENQINLVNGE-----LVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKV 1739
C+ C+ + + +QT CG R+C CI ++ C C I + + RDK ++EI + C N+ C L+ +NH C++ C + ++L K E NE C+ R TC C+Q + + +H + C + CP +CS K +I++ + P ++ GC V E + K LE I Q+ + E + + L+ + E+ +V+ + +L + V +L +L E++ II ++ ++E Q ++ + E ++N + G L+W I N+ K +A SG S F++ GY+M +IY NGDG G++ ++S++F+I++GE+D + WPFRQKV+L +L + +++ +PD + + + +P N+ +G P F E LT Y+ ++ L I V
Sbjct: 24 CAKCRLIVKDAVQTACGHRYCSPCISPLLSRGPIQCDVCGSTITKPETFRDKFADREILELHVHCVNQPHGCPWEGELRHRQNHHTKCEFNPISCVHPECGKKLSVAKLPEHLQNE-CQYREETCSYCEQPVVVARMKEHH-------EKTCPSYPVNCP-KCS---KELIRVEVHSTPFTREPRLEKGRGCENTLEVLEDHESRIKKLEQRGGGIGVNGLQSMRISENIDNEAIGDVLRRVANVEAKGADHEVLVVEAHSAVDELRREVGRLNVKLQESDDIIRRLERQLELHDQGTGLRNLAIADLEERLNTLQGTTFDSVLLWKITNVANKRSEATSGRVTSFYSPCFFTGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQDNV-EHVIDAFRPDPSSSSFQRPRAEMNIASGCPLFCS-HEQLTQHAYIRDDTMFLKIIV 476
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO32851 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STV5]) HSP 1 Score: 137.117 bits (344), Expect = 6.917e-35 Identity = 113/463 (24.41%), Postives = 207/463 (44.71%), Query Frame = 3
Query: 393 LSLNFKCSLCKNVFIEPIQTE-CGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNHSETCQYRMKQCD-LCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEM---GIDNLCDKWIDVCPQRCSNGDKVVIKMHLK-ECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSIL---SSKSARQNITLNMKPD---NNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKV 1739
L + C C+ + P+Q + CG R C C +++S + CP C E+N N DKA +EI +KC N C + E +H E C Y C+ C +Q +F +H+++ C +++TC C ++ D + + N + N CDK + + RC + H++ +CP +++ C + +GC R T E E ++T ++ + K+V L +N+ +I+ ++ + LI + + + +L+W IE+ +K+ +AK+GN + S F + + GYR+ + NGDG+GK ++SV+ +++G +D + WPF +V+ +L + R++I ++KP+ +N G+P N G +F K E++ S +Y+ +I L I V
Sbjct: 39 LQKKYICLDCEGLLWYPVQIKPCGHRVCTKCYTKLLSSS-ARCPGCMDELNENIPDIDKAFHEEIQELDVKCRNVEWNCKWEGCVNEFSSHVEKCDYSDILCENDCGAKFQRRFLTKHLDKDCPEKLITCLYCDEKHLRKDKKGHLENCPLLPCPCPNKCDKKLTI--HRCE------LDSHVENDCPRTKLMCEYEVLGCGHRITGLEGGGSREKMPKHNKTNIIAHV------------------------------------KMVADLA---LKNKELIMRFSEKLSEHGTLIEKHEKRLNDLEKIAHSQLIWRIEDYTRKMKEAKAGNTDTLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFISVLKGAFDALLKWPFDYRVTFVLLDQNDDPAQRKHIRFSIKPNPCADNEPFLGRPRLEKNASFGGAKFAKHEEIV-SRNYIKEDTIFLKISV 452
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 182.185 bits (461), Expect = 4.529e-50 Identity = 130/502 (25.90%), Postives = 223/502 (44.42%), Query Frame = 3
Query: 405 FKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLE---------INRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELK-NHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKM-----HLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQL---RTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQK------------------------------------QLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
+KC C V +P+Q +CG RFC +C ++ C C E +N ++ D A +EI + +C N+ CD +KE + H C++ QC+ CQ L K K++H + CE R + C C ++T N +I D +C K+ P +C + K I H K C S+ CPFS VGC + +I++H + +H L+ ++ + R + + E + L+ G + + L K+++ E+I+ + E+E+ QL + + E Q +G VW I + + +A SG + S FYS + GY+M L++Y NGDG G+ +LS++F++++ +YD + WPF QKV+L +L ++ R++I +PD + +P++ N+ +G P F L++L YL +I + V S
Sbjct: 28 YKCQQCLQVLRKPVQAQCGHRFCVHCFRQLTSSGPKPCQACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARCLNQGCDWTGSIKEYEAKHEGRCEFEQIQCEACQALVLRKDKDRHNDRECEERTLNCKYC--KVTFNFKDIKAH------DEICQKF----PLQCKDCGKKKIPREKFNDHAKSCAKSKSACPFSEVGCKSVVENGKISEHEHSSTMEHLRLLLPMVLSMTRTRLDTSPSGEWQEDSGLGLYRAPDDGCGAAASVPSV--DLDKKVSALENIVCVLNREVERSSLTLEAFSHQHRLDQEKIENLSNKIRQLERSLTVKDLQLSEAEQMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLL-DQNNREHIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVDLS 514
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 182.185 bits (461), Expect = 5.580e-50 Identity = 130/502 (25.90%), Postives = 223/502 (44.42%), Query Frame = 3
Query: 405 FKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLE---------INRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELK-NHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKM-----HLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQL---RTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQK------------------------------------QLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
+KC C V +P+Q +CG RFC +C ++ C C E +N ++ D A +EI + +C N+ CD +KE + H C++ QC+ CQ L K K++H + CE R + C C ++T N +I D +C K+ P +C + K I H K C S+ CPFS VGC + +I++H + +H L+ ++ + R + + E + L+ G + + L K+++ E+I+ + E+E+ QL + + E Q +G VW I + + +A SG + S FYS + GY+M L++Y NGDG G+ +LS++F++++ +YD + WPF QKV+L +L ++ R++I +PD + +P++ N+ +G P F L++L YL +I + V S
Sbjct: 35 YKCQQCLQVLRKPVQAQCGHRFCVHCFRQLTSSGPKPCQACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARCLNQGCDWTGSIKEYEAKHEGRCEFEQIQCEACQALVLRKDKDRHNDRECEERTLNCKYC--KVTFNFKDIKAH------DEICQKF----PLQCKDCGKKKIPREKFNDHAKSCAKSKSACPFSEVGCKSVVENGKISEHEHSSTMEHLRLLLPMVLSMTRTRLDTSPSGEWQEDSGLGLYRAPDDGCGAAASVPSV--DLDKKVSALENIVCVLNREVERSSLTLEAFSHQHRLDQEKIENLSNKIRQLERSLTVKDLQLSEAEQMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLL-DQNNREHIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVDLS 521
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf3 (TNF receptor associated factor 3 [Source:NCBI gene;Acc:101161601]) HSP 1 Score: 176.407 bits (446), Expect = 1.574e-48 Identity = 118/451 (26.16%), Postives = 216/451 (47.89%), Query Frame = 3
Query: 411 CSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLE-INRNKFIRDKAVEKEIFNHKIKCPNER--CDEIFLLKELKNHSETCQYRMKQCDL--CQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTS 1748
C C+ V +P QTECG RFCY+CI + ++ N CP D+E + ++K RD +EI K+ C +E C E L+++ +H C + C L C++ K +H+ C+ R TC+ C+ +M + + + + CP ++CP + + ++ H E + + QLR E +L+ +L++ L L +G L + + L+ +E + ++M+ + Q++ + S NG L+W I + +++ DA +G + + S+PFY+ GY+M ++Y NGDG GK +LS++F++++GEYD + WPF+QKV+L ++ +R+++ KPD + + + +P+ N+ +G P F+ S +L S Y+ +I + + V TS
Sbjct: 48 CEACRLVLCQPRQTECGHRFCYSCINDILSCPNPVCPA-DMEPLFKDKIFRDVCCHREIMALKVYCRSEANGCQEQMSLQQIPDHVNVCPFFEVPCPLGKCKERMMRKEIPEHLAWKCKYRESTCEFCKNKMPLTELQKHKETV---------------------------------CPAFPVSCPNHCTSSSLPRSEKLMSSH--TEKLLELELELRSLRQLRDEMESLRGTLDTVRTRLS---ALEQGGRASLETQLNRHDDMLSVHEIRL----ADMDLRFQVLETAS---------YNGTLIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPSRKHLGDAFKPDPSSSSFRRPVAEMNIASGCPLFVSQS-VLESGTYIKDDTIFIKVTVDTS 445
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: ENSORLT00000001369.2 (TNF receptor-associated factor 5 [Source:NCBI gene;Acc:101170323]) HSP 1 Score: 176.407 bits (446), Expect = 2.187e-47 Identity = 125/531 (23.54%), Postives = 238/531 (44.82%), Query Frame = 3
Query: 375 INWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLE---INRNKFIRDKAVEKEIFNHKIKCPNER-CDEIFLLKELKNHSETCQYRMKQCD--LCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSN-GDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQH--------------------QTFLMGEIVQLRT---------------ENNNLKHSLESTNQSLHEELQLVKGINKDLLKI-----------------VEKLQKQLTENESIILNIKSEMEKQKQL-------IASPSINNEN----QINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPI--NNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTST 1751
+ + +L F C +CK V + P Q CG +C++C++ + +S S P C +E I ++ +D ++EI + ++ C N C + L +L+ H ++CQY C C +L Q + ++H+N C R +C C Q + I+ + + C + CP CS + + H + CP +C F GC+ + ++ H E H + L + VQ T ++ + +H + + ++L + + + DL ++ ++ + ++L E++ +I + E +K+ +A ++N ++ ++ +G L+W I++ +++ +G + S PF++ R GY+M +K Y NGDG G+ +LS+Y +++ G++D + WPF+Q VSLS+L AR + + N +PD C+ +P + SNV G P FI L L + ++ L +KV+ T
Sbjct: 56 LKFVMKLKEEFICPICKGVVLNPQQNSCGHIYCFHCLQGLLESSLLSGPVCPVEKAAITPSEVFQDNCCKREISSLEVYCTNSPLCTSVLALNQLQEHLKSCQYEQLLCSNPGCTELLQRRLLQEHLNATCPHRRESCPHCLQPFQLS-------VIQDHVQSSCPEVKVGCPDGCSTLVPRNRLTEHGESCPEVHTDCSFKMFGCSVKGKRRKVKLHEEAAVCHHVLLVLKSSAHLEQQVVFVQKEALLRQQEVQTDTLLLSDLQEQLGSVLQQSRSQEHIVATAQRTLSRQEDALSSVQLDLQQVSCGMGSGLDELRRFKTSLDGVMQELLAAETLREHIATLEENRKRHSGLLELHVAQLALNKQHLQELELTSYDGRLIWKIKDFQKRREAEATGQHPCLSSVPFHTGRCGYKMAMKAYLNGDGEGRGTHLSLYVVLMPGDFDALLPWPFKQTVSLSVLDQSGARNHQSFNFRPDPTNTCFHQPAAESASNVAVGFPCFISLDALEAPGNAVYVKDDTLFVKVKVDT 579
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 148.288 bits (373), Expect = 3.303e-38 Identity = 121/491 (24.64%), Postives = 202/491 (41.14%), Query Frame = 3
Query: 405 FKCSLCKNVFIEPIQ-TECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKC--PNERCDEIFLLKELKNHSETCQYRMKQC-DLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNI-----------------------------------------EMGIDNL------CDKWIDVCPQRCS--NGDKVVIKMHLKE-CPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSIL----SSKSARQNITLNMKPDNNVACYGKP------INNSNVGAGQPEFIKLSEL 1685
F+C LC EP+Q + CG RFC C++ +++ CP L ++ K D +E++I + I+C E C +K+L+ H TC + + C + C + H+ C +R V C+ C + T E NH+ + E D + C ++ CP +C N + + H+K+ C ++ + CPF + GC R I +HLE + H T + + + R E IL ++ EME+ S+++ +G L+W + + +K+ +AK + + S PFY+ R GY++++ + NG+G G+ +LSVY ++ GEYD+ + WPF KV+ SIL S S Q+IT PD N + KP ++ S +G G P+FI E+
Sbjct: 16 FQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEFTGEAFE-NHQGVCPQESVYCENKCGARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPRFPVQCPNQCGTPNIAREDLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRHLEDTTKSHLTMMCNLVSRQRQE----------------------------------------------ILELRREMEEL-------SVSH-------DGVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEI 445
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000018404.1 (SMESG000018404.1) HSP 1 Score: 895.19 bits (2312), Expect = 0.000e+0 Identity = 436/443 (98.42%), Postives = 440/443 (99.32%), Query Frame = 3
Query: 423 KNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTST 1751
+NVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNH+IKCPNERCDEIFLLKELKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCD+CQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQ+NCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIH AKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDG GKDKYLSVYFMIVQGEYDDEI WPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTST
Sbjct: 5 QNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHQIKCPNERCDEIFLLKELKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDECQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQVNCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHYAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGTGKDKYLSVYFMIVQGEYDDEIAWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTST 447
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000018409.1 (SMESG000018409.1) HSP 1 Score: 368.622 bits (945), Expect = 3.843e-121 Identity = 185/467 (39.61%), Postives = 289/467 (61.88%), Query Frame = 3
Query: 354 QSRSIFFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMG-IDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTST 1751
++R+ +FI R F CS C + I+P QT+CGCRFCY+CI + + + CPNC EI N+ I+D+A+++EI N +I+C CD I K L +H + C++R++ CD C Q Y + KE H+ E C I C C +MT ++++ H NI + ID LC+ CP C++ I+ HL +CPN C +GC +++KHL ++ H T +M + L +N L+ + N E +L+K N L K +E L+ ++ NE+ I IKS++ K+ + IN++ +++V G +W + N+RQ+I DAKSG QI S+PFY +PGYR LK+YPNGDG+GKD++LS+YF+I++GEYDDE+ WPF +KV+LS++SS + QNI++ MKPD+N+ CYG+P+ N+GAGQPEF+ L +L+ S D++H SI++ ++++ +
Sbjct: 13 ETRTEYFIKNIRLECPRFVCSKCHEILIDPSQTQCGCRFCYSCINKHFASCGNICPNCQTEI-PNEIIKDRAIDREISNLEIRCLLNGCDHIGQFKYLDDHLKMCKWRLENCDKCHQTYPKQMKEIHLQEECVNGICKCSKCGLEMTRHEYQTFHVNINVECIDKLCENLSGKCPYECNSEIHNNIRNHLYDCPNKVTKCFLYELGCRFVGNQVDMSKHLSDDNVSHMTIVMSGMRNLMRKNGELEQKIVEANDKNGTETKLLKEENFQLKKQIESLRHEMRINENQIEAIKSDINSYKEQLGG-GINSDEDVSIVEGICIWTVRNVRQRITDAKSGFDTQITSKPFYLRQPGYRFSLKVYPNGDGQGKDRFLSIYFIIIKGEYDDELRWPFIEKVNLSLISSNALVQNISILMKPDSNMICYGRPVKEFNLGAGQPEFVNLGKLIDSDDFIHSGSIRIRFEMRSDS 477
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000018435.1 (SMESG000018435.1) HSP 1 Score: 364.385 bits (934), Expect = 1.866e-119 Identity = 184/465 (39.57%), Postives = 285/465 (61.29%), Query Frame = 3
Query: 360 RSIFFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMG-IDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQTST 1751
R+ +FI R F CS C + I+P QT+CGCRFCY+CI + + + CPNC EI N+ I+D+A+++EI N +I+C CD I K L +H C++R++ CD C Q Y + KE H+ E C I C C +MT ++++ H NI + ID LC+ CP C++ I+ HL +CPN C +GC +++KHL ++ H T +M + L +N L+ + E +L+K N L K +E L+ ++ NE+ I IKS++ K+ + IN++ +++V G +W + N+RQ+I DAKSG QI S+PFY +PGYR LK+YPNGDG+GKD++LS+YF+I++GEYDDE+ WPF +KV+LS++SS + QNI++ MKPD+N+ CYG+P+ N+GAGQPEF+ L +L+ S D++H SI++ ++++ +
Sbjct: 17 RTEYFIKNIRLECPRFVCSKCHEILIDPSQTQCGCRFCYSCINKHFASCENICPNCQTEIP-NEIIKDRAIDREISNLEIRCLLNGCDHIGQFKYLDDHLRMCKWRLENCDKCPQTYPKQMKEIHLQEECVNGICKCSKCGLEMTRHEYQTFHVNINVECIDKLCENLSGKCPYECNSEIHNNIRNHLYDCPNKVTKCFLYELGCQFVGNQVDMSKHLSDDNVSHMTIVMSGMRNLMRKNGELEQKIVEAKDKDGTETKLLKEENFQLKKQIESLRHEMRINENQIEAIKSDINSYKEQLGG-GINSDEDVSIVEGICIWTVRNVRQRITDAKSGFDTQITSKPFYLRQPGYRFSLKVYPNGDGQGKDRFLSIYFIIIKGEYDDELRWPFIEKVNLSLISSNALVQNISILMKPDSNMICYGRPVKEFNLGAGQPEFVNLGKLIDSDDFIHSGSIRIRFEMRSDS 479
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000027153.1 (SMESG000027153.1) HSP 1 Score: 261.922 bits (668), Expect = 2.082e-80 Identity = 154/460 (33.48%), Postives = 244/460 (53.04%), Query Frame = 3
Query: 393 LSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNSSCP-------NCDLEINRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHRNIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTT-RATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQ-INLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKVQT 1745
LS KC LC+ + QT CGC+ C NCI++Y+ N CP N L ++ + D A KEI + K+KCP + C L+ + H +C++R C+ CQ Q K KE H CE R + C+ C ++M+ D + H N + ++ C K+ +CP C KV +K HLK C ++ CPF ++ C + T + KHL E H + L+ +I +E+T ++L +EL+ K + K+LL + +K + + + I +K++ +P EN+ + N +W + K DA+SG +V + S+PFY+ GY+M L+IYP GDG GK +LSV+F I++GE+DD + WPF+QKV+LSI+ ++ ++ + KPD ACY KP++ N+ +G P+FI LS ++ + Y +I L I V T
Sbjct: 22 LSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDED-INADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDR--EDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKI-----------KDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKS------FPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDT 461
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000039089.1 (SMESG000039089.1) HSP 1 Score: 248.825 bits (634), Expect = 1.591e-75 Identity = 141/473 (29.81%), Postives = 254/473 (53.70%), Query Frame = 3
Query: 327 NYTENFRNSQSRSIFFINWNRQLSLNFKCSLCKNVFIEPIQTECGCRFCYNCIENYINNSNS-SCPNCDLEINRNKFIRDKAVEKEIFNHKIKCPNERCDEIFLLKELKNHSETCQYRMKQCDLCQQLYQFKFKEQHMNELCERRIVTCDDCQQQMTSNDHEINHR-NIEMGIDNLCDKWIDVCPQRCSNGDKVVIKMHLKECPNSQINCPFSNVGCTTRATVNEINKHLEIESFQHQTFLMGEIVQLRTENNNLKHSLESTNQSLHEELQLVKGINKDLLKIVEKLQKQLTENESIILNIKSEMEKQKQLIASPSINNENQINLVNGELVWIIENIRQKIHDAKSGNQVQIISEPFYSIRPGYRMRLKIYPNGDGRGKDKYLSVYFMIVQGEYDDEIVWPFRQKVSLSILSSKSARQNITLNMKPDNNVACYGKPINNSNVGAGQPEFIKLSELLTSLDYLHGTSIKLAIKV 1739
N +N + + R F L+ N KC +C + + +QT+CGCR+C CIE+++ NS S C I+ + D A+ KEI +KC + C+ +LK++ +H +C+Y C+ C+ K H+ + C +R+V C +C+ +M ++EI + ++++ DN+C K +D CP C V + H KEC + CPF +GC+ T +++ H++ E H L+ E ++++ E +L+ L +++++ EL ++ + + + + S+ + ++ +A+ +N+ +IN NG +W +E+ + +A+ GN++ + SEPFY+ GY+M +KIYP GDG GK +LSV+F +++G++DD +VWPF+ KV+L+IL K+ + + KPD CY +P N+ +G P+FI ++L Y+ +I L I V
Sbjct: 7 NLPDNIKRYRKRRFPF-----NLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCSTKGCSTIIST---MPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRVVKCLNCESRM---EYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFPAHIRTLVEEFIKMKKEITSLETKLIESSKTIKLELS---NFQNEISTKISNIDQMSNSSLSLQSSSSLTLQSSASSMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQEY--YMKNDTIFLKIVV 463 The following BLAST results are available for this feature:
BLAST of TNF receptor-associated factor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TNF receptor-associated factor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of TNF receptor-associated factor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002663 ID=SMED30002663|Name=TNF receptor-associated factor|organism=Schmidtea mediterranea sexual|type=transcript|length=1854bpback to top protein sequence of SMED30002663-orf-1 >SMED30002663-orf-1 ID=SMED30002663-orf-1|Name=SMED30002663-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=490bp MTKFTDLLSMPEKYNYTENFRNSQSRSIFFINWNRQLSLNFKCSLCKNVFback to top Annotated Terms
The following terms have been associated with this transcript:
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