Epithelial splicing regulatory protein 1/2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002619 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 26
Homology
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Human
Match: ESRP2 (epithelial splicing regulatory protein 2 [Source:HGNC Symbol;Acc:HGNC:26152]) HSP 1 Score: 152.14 bits (383), Expect = 2.605e-37 Identity = 126/438 (28.77%), Postives = 210/438 (47.95%), Query Frame = 3
Query: 606 LMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQ--AIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNV---------LVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQNLD----EISNFLQIEKPGGT---TMSIICYMSNAILQLTQ--LGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKA-KNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
L+ T G G DLG DET ++ + +Q+++ + Q + L+ +A++L S RE + L S+ S L L + +N +V L +D Q + LR VLH E +N+ L + ++ +Y+L E + S C D ++ L +E + + M IL L + LF VIK Y+ D ++ + V+ + + +++ + FF+GLN+A GG+A+ + ++GRR+ + LI+F D QRD+AL R KHHM R+I + EF+KIAG + V +L + +DQ+++R++GLP++ ++L F + V G+ V+ G GDAF +F E +AQ A + KGM +G RY+E+F ST E+ QV+
Sbjct: 30 LVVLFGATAGALGRDLGSDETDLILLVWQVVEPRSRQVGTLHKSLVRAEAAAL------------STQCREASGL-SADSLARAEPLDKVLQQFSQLVNGDVALLGGGPYMLCTDGQQL-----------LRQVLHPEASRKNLVLPDMFFSFYDLRREFHMQHPSTCPARDLTVATMAQGLGLETDATEDDFGVWEVKTMVAVILHLLKEPSSQLFSKPEVIKQKYETGPCSKADVVDSETVVRARGLPWQSSDQDVARFFKGLNVARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHM---GVRYIEVYKATGEEFVKIAGGTSLEVARFLSR---EDQVILRLRGLPFSAGPTDVLGFL-GPECPVTGGTEGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGM-LGKRYIELFRSTAAEVQQVL 435
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Human
Match: ESRP1 (epithelial splicing regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:25966]) HSP 1 Score: 147.517 bits (371), Expect = 3.136e-36 Identity = 119/434 (27.42%), Postives = 210/434 (48.39%), Query Frame = 3
Query: 585 MNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDL-LSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFT--SSKCQNLD--EISNFLQIEKPGGTT---MSIICYMSNAILQLTQ--LGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
M S L+ +T G G LG DE ++ + ++++DL+N + L + PD++ ++ +E T + + S SS S +L AL + + ++ + + + + G L +R +LH E +N+ L +Y +++L E S LD ++ +L EK + S + M N IL + H F + ++ + I+ + V+ + + +++ I FF+GLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM +R+I + +F+KIAG + V +L + ++Q+++R++GLP+T T E++ FF + + GI V G GDAFV+F E AQ A +G RY+E+F ST E+ QV+
Sbjct: 1 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKV----------GQLHEVLVRPDQLELTEDCKEETKIDVESLSSAS--QLDQALRQFNQSVSNELNIGVGTSFCL--CTDGQLHVRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM---GTRYIEVYKATGEDFLKIAGGTSNEVAQFLSK---ENQVIVRMRGLPFTATAEEVVAFFGQH-CPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVL 413
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Human
Match: ESRP1 (epithelial splicing regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:25966]) HSP 1 Score: 147.132 bits (370), Expect = 4.136e-36 Identity = 119/434 (27.42%), Postives = 210/434 (48.39%), Query Frame = 3
Query: 585 MNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDL-LSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFT--SSKCQNLD--EISNFLQIEKPGGTT---MSIICYMSNAILQLTQ--LGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
M S L+ +T G G LG DE ++ + ++++DL+N + L + PD++ ++ +E T + + S SS S +L AL + + ++ + + + + G L +R +LH E +N+ L +Y +++L E S LD ++ +L EK + S + M N IL + H F + ++ + I+ + V+ + + +++ I FF+GLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM +R+I + +F+KIAG + V +L + ++Q+++R++GLP+T T E++ FF + + GI V G GDAFV+F E AQ A +G RY+E+F ST E+ QV+
Sbjct: 1 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKV----------GQLHEVLVRPDQLELTEDCKEETKIDVESLSSAS--QLDQALRQFNQSVSNELNIGVGTSFCL--CTDGQLHVRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM---GTRYIEVYKATGEDFLKIAGGTSNEVAQFLSK---ENQVIVRMRGLPFTATAEEVVAFFGQH-CPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVL 413
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Human
Match: ESRP1 (epithelial splicing regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:25966]) HSP 1 Score: 147.517 bits (371), Expect = 5.224e-36 Identity = 119/434 (27.42%), Postives = 210/434 (48.39%), Query Frame = 3
Query: 585 MNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDL-LSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFT--SSKCQNLD--EISNFLQIEKPGGTT---MSIICYMSNAILQLTQ--LGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
M S L+ +T G G LG DE ++ + ++++DL+N + L + PD++ ++ +E T + + S SS S +L AL + + ++ + + + + G L +R +LH E +N+ L +Y +++L E S LD ++ +L EK + S + M N IL + H F + ++ + I+ + V+ + + +++ I FF+GLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM +R+I + +F+KIAG + V +L + ++Q+++R++GLP+T T E++ FF + + GI V G GDAFV+F E AQ A +G RY+E+F ST E+ QV+
Sbjct: 1 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKV----------GQLHEVLVRPDQLELTEDCKEETKIDVESLSSAS--QLDQALRQFNQSVSNELNIGVGTSFCL--CTDGQLHVRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM---GTRYIEVYKATGEDFLKIAGGTSNEVAQFLSK---ENQVIVRMRGLPFTATAEEVVAFFGQH-CPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVL 413
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Human
Match: ESRP1 (epithelial splicing regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:25966]) HSP 1 Score: 147.517 bits (371), Expect = 5.369e-36 Identity = 119/434 (27.42%), Postives = 210/434 (48.39%), Query Frame = 3
Query: 585 MNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDL-LSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFT--SSKCQNLD--EISNFLQIEKPGGTT---MSIICYMSNAILQLTQ--LGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
M S L+ +T G G LG DE ++ + ++++DL+N + L + PD++ ++ +E T + + S SS S +L AL + + ++ + + + + G L +R +LH E +N+ L +Y +++L E S LD ++ +L EK + S + M N IL + H F + ++ + I+ + V+ + + +++ I FF+GLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM +R+I + +F+KIAG + V +L + ++Q+++R++GLP+T T E++ FF + + GI V G GDAFV+F E AQ A +G RY+E+F ST E+ QV+
Sbjct: 1 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKV----------GQLHEVLVRPDQLELTEDCKEETKIDVESLSSAS--QLDQALRQFNQSVSNELNIGVGTSFCL--CTDGQLHVRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM---GTRYIEVYKATGEDFLKIAGGTSNEVAQFLSK---ENQVIVRMRGLPFTATAEEVVAFFGQH-CPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVL 413
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Celegans
Match: sym-2 (RNA-binding protein sym-2 [Source:UniProtKB/Swiss-Prot;Acc:Q22708]) HSP 1 Score: 117.472 bits (293), Expect = 6.528e-27 Identity = 88/317 (27.76%), Postives = 148/317 (46.69%), Query Frame = 3
Query: 1224 YKPIVFHVNDEIEPD---IVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMS-EGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIA-GYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKPKQNKQITKPTDSVNQENIKSSQKAVMSGTVTKYIPMEASDNDFVRYLADHRGLCLLSSRSHLYSPIGYISYVAFFK--NSSDASATIKALRD 2153
Y+P + E+ D +V + + ++ + + FF GL+I GGIA+ +S EGRR+ ++L++F + RD+AL R ++ + SR+I + EFM +A G E+++ + + I++R++GLPY T +I FF+ + + I + ++ G GDAFV FE E AQ+ IG RY+E+F ST E+ QV+ I P + P + K + G +P EA+ V +L D + +Y+ G+ S AF + N ASA + +
Sbjct: 163 YQPAPILEDQEVGADGDNVVCRARGLPWQASDHHVAQFFAGLDIVPGGIALCLSSEGRRNGEVLVQFSSQESRDLALKRHRNFLL---SRYIEVYKAGLDEFMHVATGSSTEAMEFV-----SANAIIVRMRGLPYDCTDAQIRTFFEPLKLT-----DKILFITRTDGRPTGDAFVQFETEEDAQQGLLKHRQVIGQRYIELFKSTAAEVQQVVKRCNLINSSPAVANAVEAPEE-------KKKDCVRLRG-----LPYEATVQHIVTFLGDFATMVKFQGVHMVYNNQGHPSGEAFIQMINEQAASACAAGVHN 454
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Celegans
Match: sym-2 (RNA-binding protein sym-2 [Source:UniProtKB/Swiss-Prot;Acc:Q22708]) HSP 1 Score: 71.2478 bits (173), Expect = 7.143e-13 Identity = 53/193 (27.46%), Postives = 83/193 (43.01%), Query Frame = 3
Query: 1581 DQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKPKQNKQITKPTDSVNQENIKSSQKAVMSGTVTKYIPMEASDNDFVRYLADHRGLCLLSSRSHLYSPIGYISYVAFFK--NSSDASATIKALRD 2153
+ I++R++GLPY T +I FF+ + + I + ++ G GDAFV FE E AQ+ IG RY+E+F ST E+ QV+ I P + P + K + G +P EA+ V +L D + +Y+ G+ S AF + N ASA + +
Sbjct: 7 NAIIVRMRGLPYDCTDAQIRTFFEPLKLT-----DKILFITRTDGRPTGDAFVQFETEEDAQQGLLKHRQVIGQRYIELFKSTAAEVQQVVKRCNLINSSPAVANAVEAPEE-------KKKDCVRLRG-----LPYEATVQHIVTFLGDFATMVKFQGVHMVYNNQGHPSGEAFIQMINEQAASACAAGVHN 182 HSP 2 Score: 65.4698 bits (158), Expect = 5.891e-11 Identity = 48/202 (23.76%), Postives = 90/202 (44.55%), Query Frame = 3
Query: 1269 IVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYEN-----ESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAK-----NLKGMTIGNRYMEIFYSTPPEMN 1844
I++ ++ + Y QI FF L + D + + ++GR + ++FE + LL+ H + R+I + + E ++ N +V +E E + + +R++GLPY T I+ F V+F G+ +V + G +G+AF+ NE A N + RY+E+F ++ E+N
Sbjct: 9 IIVRMRGLPYDCTDAQIRTFFEPLKLTDKILFITRTDGRPTGDAFVQFETEEDAQQGLLK---HRQVIGQRYIELFKSTAAEVQQVVKRCNLINSSPAVANAVEAPEEKKKDCVRLRGLPYEATVQHIVTFLGDFATMVKF--QGVHMVYNNQGHPSGEAFIQMINEQAASACAAGVHNNFMSVGKKKRYIEVFQASAEELN 205
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Celegans
Match: sym-2 (RNA-binding protein sym-2 [Source:UniProtKB/Swiss-Prot;Acc:Q22708]) HSP 1 Score: 71.2478 bits (173), Expect = 7.143e-13 Identity = 53/193 (27.46%), Postives = 83/193 (43.01%), Query Frame = 3
Query: 1581 DQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKPKQNKQITKPTDSVNQENIKSSQKAVMSGTVTKYIPMEASDNDFVRYLADHRGLCLLSSRSHLYSPIGYISYVAFFK--NSSDASATIKALRD 2153
+ I++R++GLPY T +I FF+ + + I + ++ G GDAFV FE E AQ+ IG RY+E+F ST E+ QV+ I P + P + K + G +P EA+ V +L D + +Y+ G+ S AF + N ASA + +
Sbjct: 7 NAIIVRMRGLPYDCTDAQIRTFFEPLKLT-----DKILFITRTDGRPTGDAFVQFETEEDAQQGLLKHRQVIGQRYIELFKSTAAEVQQVVKRCNLINSSPAVANAVEAPEE-------KKKDCVRLRG-----LPYEATVQHIVTFLGDFATMVKFQGVHMVYNNQGHPSGEAFIQMINEQAASACAAGVHN 182 HSP 2 Score: 65.4698 bits (158), Expect = 5.891e-11 Identity = 48/202 (23.76%), Postives = 90/202 (44.55%), Query Frame = 3
Query: 1269 IVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYEN-----ESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAK-----NLKGMTIGNRYMEIFYSTPPEMN 1844
I++ ++ + Y QI FF L + D + + ++GR + ++FE + LL+ H + R+I + + E ++ N +V +E E + + +R++GLPY T I+ F V+F G+ +V + G +G+AF+ NE A N + RY+E+F ++ E+N
Sbjct: 9 IIVRMRGLPYDCTDAQIRTFFEPLKLTDKILFITRTDGRPTGDAFVQFETEEDAQQGLLK---HRQVIGQRYIELFKSTAAEVQQVVKRCNLINSSPAVANAVEAPEEKKKDCVRLRGLPYEATVQHIVTFLGDFATMVKF--QGVHMVYNNQGHPSGEAFIQMINEQAASACAAGVHNNFMSVGKKKRYIEVFQASAEELN 205
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Celegans
Match: hrpf-1 (HnRNP F homolog [Source:UniProtKB/TrEMBL;Acc:H2KZN0]) HSP 1 Score: 51.2174 bits (121), Expect = 2.343e-6 Identity = 26/80 (32.50%), Postives = 43/80 (53.75%), Query Frame = 3
Query: 1590 LIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYST 1829
++R++GLP++VT +I +F + +GI L + G+A+V FE Q AK IG+RY+E+F +T
Sbjct: 124 IVRLRGLPFSVTSRDISDFL----APLPIVRDGILLPDQQRARPGGEAYVCFETMESVQIAKQRHMKNIGHRYIEVFEAT 199
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Celegans
Match: hrpf-1 (HnRNP F homolog [Source:UniProtKB/TrEMBL;Acc:H2KZN0]) HSP 1 Score: 50.447 bits (119), Expect = 6.334e-6 Identity = 26/80 (32.50%), Postives = 43/80 (53.75%), Query Frame = 3
Query: 1590 LIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYST 1829
++R++GLP++VT +I +F + +GI L + G+A+V FE Q AK IG+RY+E+F +T
Sbjct: 124 IVRLRGLPFSVTSRDISDFL----APLPIVRDGILLPDQQRARPGGEAYVCFETMESVQIAKQRHMKNIGHRYIEVFEAT 199
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Fly
Match: fus (gene:FBgn0023441 transcript:FBtr0302330) HSP 1 Score: 171.014 bits (432), Expect = 2.284e-43 Identity = 135/475 (28.42%), Postives = 225/475 (47.37%), Query Frame = 3
Query: 606 LMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQ------------------------ASS--LLDPSANPDKIHISVPAREMTD----LLSSPSSHSTFK-LQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQN----LDEISNFLQI----------EKPGGTTMSII----CY------MSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSND---VEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
+++ ++ TCG G+ LG DE I+ + F L+++S Q +G K IL++ ASS L AN S + + +L + + K L +A+ E D+++ L E+ V G LPLR LHRE +++ L Y+ + +L E + S + ++ LQ E G +S + Y M I L Q GH F + ++ +P + ++DE++ + ++ + + +++ I FFRGLN+A GG+A+ +S GRR+ + LI+F + RD+AL R KHH+ +R+I + +F+ IAG + + +L + Q++IR++GLPY T ++L+FF + D V + G+ V+K G GDAFV+F NE A KA +IG RY+E+F ST E+ QV+
Sbjct: 7 VVSLYIATCGQNGSGLGSDEKEIILLVFVLLEVSTGQIVGTKQILVRPDGYFIKDRTISSSSDNSSVTNNTASSPPLAIGDANNGSGSTSGNGNSLENGSELILPIAEAQAAGKPLSEAIEEFDAYLRSLSL----HDTEIKLVTDGQLPLRQCLHREASAKDVELPAYYNRFSDLRKEFLRYKSGDLARALVPVKDVKKMLQAPTLPMPQSIAEMLGELNISSVEDNDFYIRESRDMVTVIQTLLQAGHKFAANELVNLVLEPGICSIDDEVDGNCIVRARGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHI---GTRYIEVYRASGEDFLAIAGGASNEAQAFLSK---GAQVIIRMRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQRYIELFRSTTAEVQQVL 471
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Fly
Match: fus (gene:FBgn0023441 transcript:FBtr0087345) HSP 1 Score: 171.014 bits (432), Expect = 2.557e-43 Identity = 135/475 (28.42%), Postives = 225/475 (47.37%), Query Frame = 3
Query: 606 LMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQ------------------------ASS--LLDPSANPDKIHISVPAREMTD----LLSSPSSHSTFK-LQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQN----LDEISNFLQI----------EKPGGTTMSII----CY------MSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSND---VEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
+++ ++ TCG G+ LG DE I+ + F L+++S Q +G K IL++ ASS L AN S + + +L + + K L +A+ E D+++ L E+ V G LPLR LHRE +++ L Y+ + +L E + S + ++ LQ E G +S + Y M I L Q GH F + ++ +P + ++DE++ + ++ + + +++ I FFRGLN+A GG+A+ +S GRR+ + LI+F + RD+AL R KHH+ +R+I + +F+ IAG + + +L + Q++IR++GLPY T ++L+FF + D V + G+ V+K G GDAFV+F NE A KA +IG RY+E+F ST E+ QV+
Sbjct: 7 VVSLYIATCGQNGSGLGSDEKEIILLVFVLLEVSTGQIVGTKQILVRPDGYFIKDRTISSSSDNSSVTNNTASSPPLAIGDANNGSGSTSGNGNSLENGSELILPIAEAQAAGKPLSEAIEEFDAYLRSLSL----HDTEIKLVTDGQLPLRQCLHREASAKDVELPAYYNRFSDLRKEFLRYKSGDLARALVPVKDVKKMLQAPTLPMPQSIAEMLGELNISSVEDNDFYIRESRDMVTVIQTLLQAGHKFAANELVNLVLEPGICSIDDEVDGNCIVRARGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHI---GTRYIEVYRASGEDFLAIAGGASNEAQAFLSK---GAQVIIRMRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQRYIELFRSTTAEVQQVL 471
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Fly
Match: fus (gene:FBgn0023441 transcript:FBtr0087343) HSP 1 Score: 171.4 bits (433), Expect = 2.648e-43 Identity = 135/475 (28.42%), Postives = 225/475 (47.37%), Query Frame = 3
Query: 606 LMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQ------------------------ASS--LLDPSANPDKIHISVPAREMTD----LLSSPSSHSTFK-LQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQN----LDEISNFLQI----------EKPGGTTMSII----CY------MSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSND---VEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
+++ ++ TCG G+ LG DE I+ + F L+++S Q +G K IL++ ASS L AN S + + +L + + K L +A+ E D+++ L E+ V G LPLR LHRE +++ L Y+ + +L E + S + ++ LQ E G +S + Y M I L Q GH F + ++ +P + ++DE++ + ++ + + +++ I FFRGLN+A GG+A+ +S GRR+ + LI+F + RD+AL R KHH+ +R+I + +F+ IAG + + +L + Q++IR++GLPY T ++L+FF + D V + G+ V+K G GDAFV+F NE A KA +IG RY+E+F ST E+ QV+
Sbjct: 7 VVSLYIATCGQNGSGLGSDEKEIILLVFVLLEVSTGQIVGTKQILVRPDGYFIKDRTISSSSDNSSVTNNTASSPPLAIGDANNGSGSTSGNGNSLENGSELILPIAEAQAAGKPLSEAIEEFDAYLRSLSL----HDTEIKLVTDGQLPLRQCLHREASAKDVELPAYYNRFSDLRKEFLRYKSGDLARALVPVKDVKKMLQAPTLPMPQSIAEMLGELNISSVEDNDFYIRESRDMVTVIQTLLQAGHKFAANELVNLVLEPGICSIDDEVDGNCIVRARGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHI---GTRYIEVYRASGEDFLAIAGGASNEAQAFLSK---GAQVIIRMRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQRYIELFRSTTAEVQQVL 471
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Fly
Match: fus (gene:FBgn0023441 transcript:FBtr0087344) HSP 1 Score: 171.4 bits (433), Expect = 2.648e-43 Identity = 135/475 (28.42%), Postives = 225/475 (47.37%), Query Frame = 3
Query: 606 LMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQ------------------------ASS--LLDPSANPDKIHISVPAREMTD----LLSSPSSHSTFK-LQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQN----LDEISNFLQI----------EKPGGTTMSII----CY------MSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSND---VEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
+++ ++ TCG G+ LG DE I+ + F L+++S Q +G K IL++ ASS L AN S + + +L + + K L +A+ E D+++ L E+ V G LPLR LHRE +++ L Y+ + +L E + S + ++ LQ E G +S + Y M I L Q GH F + ++ +P + ++DE++ + ++ + + +++ I FFRGLN+A GG+A+ +S GRR+ + LI+F + RD+AL R KHH+ +R+I + +F+ IAG + + +L + Q++IR++GLPY T ++L+FF + D V + G+ V+K G GDAFV+F NE A KA +IG RY+E+F ST E+ QV+
Sbjct: 7 VVSLYIATCGQNGSGLGSDEKEIILLVFVLLEVSTGQIVGTKQILVRPDGYFIKDRTISSSSDNSSVTNNTASSPPLAIGDANNGSGSTSGNGNSLENGSELILPIAEAQAAGKPLSEAIEEFDAYLRSLSL----HDTEIKLVTDGQLPLRQCLHREASAKDVELPAYYNRFSDLRKEFLRYKSGDLARALVPVKDVKKMLQAPTLPMPQSIAEMLGELNISSVEDNDFYIRESRDMVTVIQTLLQAGHKFAANELVNLVLEPGICSIDDEVDGNCIVRARGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHI---GTRYIEVYRASGEDFLAIAGGASNEAQAFLSK---GAQVIIRMRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQRYIELFRSTTAEVQQVL 471
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Fly
Match: fus (gene:FBgn0023441 transcript:FBtr0087346) HSP 1 Score: 171.4 bits (433), Expect = 2.648e-43 Identity = 135/475 (28.42%), Postives = 225/475 (47.37%), Query Frame = 3
Query: 606 LMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQ------------------------ASS--LLDPSANPDKIHISVPAREMTD----LLSSPSSHSTFK-LQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQN----LDEISNFLQI----------EKPGGTTMSII----CY------MSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSND---VEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
+++ ++ TCG G+ LG DE I+ + F L+++S Q +G K IL++ ASS L AN S + + +L + + K L +A+ E D+++ L E+ V G LPLR LHRE +++ L Y+ + +L E + S + ++ LQ E G +S + Y M I L Q GH F + ++ +P + ++DE++ + ++ + + +++ I FFRGLN+A GG+A+ +S GRR+ + LI+F + RD+AL R KHH+ +R+I + +F+ IAG + + +L + Q++IR++GLPY T ++L+FF + D V + G+ V+K G GDAFV+F NE A KA +IG RY+E+F ST E+ QV+
Sbjct: 7 VVSLYIATCGQNGSGLGSDEKEIILLVFVLLEVSTGQIVGTKQILVRPDGYFIKDRTISSSSDNSSVTNNTASSPPLAIGDANNGSGSTSGNGNSLENGSELILPIAEAQAAGKPLSEAIEEFDAYLRSLSL----HDTEIKLVTDGQLPLRQCLHREASAKDVELPAYYNRFSDLRKEFLRYKSGDLARALVPVKDVKKMLQAPTLPMPQSIAEMLGELNISSVEDNDFYIRESRDMVTVIQTLLQAGHKFAANELVNLVLEPGICSIDDEVDGNCIVRARGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHI---GTRYIEVYRASGEDFLAIAGGASNEAQAFLSK---GAQVIIRMRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQRYIELFRSTTAEVQQVL 471
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Zebrafish
Match: esrp1 (epithelial splicing regulatory protein 1 [Source:NCBI gene;Acc:560190]) HSP 1 Score: 150.984 bits (380), Expect = 3.144e-37 Identity = 130/478 (27.20%), Postives = 229/478 (47.91%), Query Frame = 3
Query: 651 LGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQ----NLDEISNFLQIEKPGGTTMSIICYMSNAILQLTQL---------GHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI---SAAQNIPFKPKQNKQITKPTDSVNQENIKSSQKAVMSGTVTKYIPMEASDNDFVRYLADH 2033
LG DE I+Q+ +Q++DL+ +A Q + LL PD I +S +E++ L + + L+ A+++++ + V T + G L +R VLH E +NI L + ++ +++L E S+ + NL +++ L + S+ + + + Q+ + H F + ++ + ++ + V+ + + +++ I FFRGLNIA GG A+ + ++GRR+ + L++FE + RD+AL R KHHM R+I + +F+KIAG + V +L + ++QI++R++GLP+ T ++L FF S V GI V+ G GDAFV+F E AQ A +G RY+E+F ST E+ QV+ S+A IP P + P V Q ++ V + +P +AS D + +L ++
Sbjct: 23 LGSDEKEIVQLVWQVVDLATKKAG-------QVNELL---VKPDHIELSEECQELSGL-TDEALTPVDPLEVAIDQLNQRLCAEVDTGAGNTFYL--CTDGQLHVRQVLHPEASSKNILLPDCFFSFFDLRKEFKKEFPSEVKLKDLNLQVMADHLNV----AVDSSLHAFTAYKVQQMVDIVLALISEPTCHEFTFPEKVNEKFETGTCSKMERVDDNTVIRARGLPWQSSDQDIARFFRGLNIAKGGAALCLNAQGRRNGEALVRFESEEHRDLALQRHKHHM---GGRYIEVYKATGEDFLKIAGGTSNEVASFLSR---ENQIIVRMRGLPFNATAEQVLQFF-SPACPVTDGSEGILFVRFPDGRPTGDAFVLFSCEEHAQNALKKHKDMLGKRYIELFKSTAAEVQQVLNKYSSAPLIPVAPSPILSVVAPPTFVPQ---TAAVPGVRDCVRLRGLPYDASIQDILVFLGEY 473
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Zebrafish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:572992]) HSP 1 Score: 145.206 bits (365), Expect = 2.298e-35 Identity = 123/443 (27.77%), Postives = 208/443 (46.95%), Query Frame = 3
Query: 606 LMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKL--ILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNV--LVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQN------------LDEISNFLQIEKPGGTTMSIICYMSNAILQLTQ--LGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPF 1877
L+ F T G G LG DE ++ + +Q++DL N+ GKL L+Q PD + +S +E T L + + L+ L + ++ + L T+ + G L +R VLH E +N+ L +Y + +L E C N LD + +E+ G + + M IL + H F + + ++ + ++ + V+ + + +++ I FF+GLNIA GG+A+ + ++GRR+ + L++F + RD+AL R KHHM SR+I + EF+KIAG + V +L + ++Q++IR++GLP+T T ++L F + V G+ V+ G GDAFV+F E AQ A +G RY+E+F ST E+ QV++ + P
Sbjct: 8 LVVFFGATAGANGGKLGSDERELILLVWQIVDLHENKV--GKLHRTLVQ----------PDSVDLSEQCKEETGLTAEELCKAE-PLESVLQQFHQSVSAELKSLGRSSYTL----CVDGPLLIRQVLHPEASKKNLVLPECFYTFVDLKKEFH----KCCPNAGPVKDLTLPSMLDYVCIQATVEQEAG--LREVKDMVLLILHVLAEPYNHKFSAFETVNYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALDRHKHHM---GSRYIEVYKATGEEFLKIAGGTSNEVAQFLSK---ENQMIIRMRGLPFTATPQDVLGFL-GPECPVTDGTEGLLFVKYPDGRPTGDAFVLFACEEYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPL 420
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Zebrafish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:572992]) HSP 1 Score: 145.206 bits (365), Expect = 2.298e-35 Identity = 123/443 (27.77%), Postives = 208/443 (46.95%), Query Frame = 3
Query: 606 LMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKL--ILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNV--LVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQN------------LDEISNFLQIEKPGGTTMSIICYMSNAILQLTQ--LGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPF 1877
L+ F T G G LG DE ++ + +Q++DL N+ GKL L+Q PD + +S +E T L + + L+ L + ++ + L T+ + G L +R VLH E +N+ L +Y + +L E C N LD + +E+ G + + M IL + H F + + ++ + ++ + V+ + + +++ I FF+GLNIA GG+A+ + ++GRR+ + L++F + RD+AL R KHHM SR+I + EF+KIAG + V +L + ++Q++IR++GLP+T T ++L F + V G+ V+ G GDAFV+F E AQ A +G RY+E+F ST E+ QV++ + P
Sbjct: 8 LVVFFGATAGANGGKLGSDERELILLVWQIVDLHENKV--GKLHRTLVQ----------PDSVDLSEQCKEETGLTAEELCKAE-PLESVLQQFHQSVSAELKSLGRSSYTL----CVDGPLLIRQVLHPEASKKNLVLPECFYTFVDLKKEFH----KCCPNAGPVKDLTLPSMLDYVCIQATVEQEAG--LREVKDMVLLILHVLAEPYNHKFSAFETVNYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALDRHKHHM---GSRYIEVYKATGEEFLKIAGGTSNEVAQFLSK---ENQMIIRMRGLPFTATPQDVLGFL-GPECPVTDGTEGLLFVKYPDGRPTGDAFVLFACEEYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPL 420
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Zebrafish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:572992]) HSP 1 Score: 145.591 bits (366), Expect = 2.325e-35 Identity = 123/443 (27.77%), Postives = 208/443 (46.95%), Query Frame = 3
Query: 606 LMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKL--ILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNV--LVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQN------------LDEISNFLQIEKPGGTTMSIICYMSNAILQLTQ--LGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPF 1877
L+ F T G G LG DE ++ + +Q++DL N+ GKL L+Q PD + +S +E T L + + L+ L + ++ + L T+ + G L +R VLH E +N+ L +Y + +L E C N LD + +E+ G + + M IL + H F + + ++ + ++ + V+ + + +++ I FF+GLNIA GG+A+ + ++GRR+ + L++F + RD+AL R KHHM SR+I + EF+KIAG + V +L + ++Q++IR++GLP+T T ++L F + V G+ V+ G GDAFV+F E AQ A +G RY+E+F ST E+ QV++ + P
Sbjct: 8 LVVFFGATAGANGGKLGSDERELILLVWQIVDLHENKV--GKLHRTLVQ----------PDSVDLSEQCKEETGLTAEELCKAE-PLESVLQQFHQSVSAELKSLGRSSYTL----CVDGPLLIRQVLHPEASKKNLVLPECFYTFVDLKKEFH----KCCPNAGPVKDLTLPSMLDYVCIQATVEQEAG--LREVKDMVLLILHVLAEPYNHKFSAFETVNYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALDRHKHHM---GSRYIEVYKATGEEFLKIAGGTSNEVAQFLSK---ENQMIIRMRGLPFTATPQDVLGFL-GPECPVTDGTEGLLFVKYPDGRPTGDAFVLFACEEYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPL 420
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Zebrafish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:572992]) HSP 1 Score: 145.591 bits (366), Expect = 2.325e-35 Identity = 123/443 (27.77%), Postives = 208/443 (46.95%), Query Frame = 3
Query: 606 LMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKL--ILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNV--LVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQN------------LDEISNFLQIEKPGGTTMSIICYMSNAILQLTQ--LGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPF 1877
L+ F T G G LG DE ++ + +Q++DL N+ GKL L+Q PD + +S +E T L + + L+ L + ++ + L T+ + G L +R VLH E +N+ L +Y + +L E C N LD + +E+ G + + M IL + H F + + ++ + ++ + V+ + + +++ I FF+GLNIA GG+A+ + ++GRR+ + L++F + RD+AL R KHHM SR+I + EF+KIAG + V +L + ++Q++IR++GLP+T T ++L F + V G+ V+ G GDAFV+F E AQ A +G RY+E+F ST E+ QV++ + P
Sbjct: 8 LVVFFGATAGANGGKLGSDERELILLVWQIVDLHENKV--GKLHRTLVQ----------PDSVDLSEQCKEETGLTAEELCKAE-PLESVLQQFHQSVSAELKSLGRSSYTL----CVDGPLLIRQVLHPEASKKNLVLPECFYTFVDLKKEFH----KCCPNAGPVKDLTLPSMLDYVCIQATVEQEAG--LREVKDMVLLILHVLAEPYNHKFSAFETVNYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALDRHKHHM---GSRYIEVYKATGEEFLKIAGGTSNEVAQFLSK---ENQMIIRMRGLPFTATPQDVLGFL-GPECPVTDGTEGLLFVKYPDGRPTGDAFVLFACEEYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPL 420
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Xenopus
Match: atf1 (activating transcription factor 1 [Source:Xenbase;Acc:XB-GENE-971677]) HSP 1 Score: 142.51 bits (358), Expect = 2.153e-34 Identity = 112/436 (25.69%), Postives = 199/436 (45.64%), Query Frame = 3
Query: 606 LMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETR-------------FRXXXXXXXXXXXXXLFDEVSIFTSSKCQNLDEISNFL------QIEKPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
L+ T G G+ LG DE ++Q+ +++I+L+N + L + + PD + ++ +E+T + + S + +L+ AL + + + + + + + G L +R VLH E F + +E+ + + C L + +++ G +++I N L LFHS + + I+ + ++ + + +++ I FF+GLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM GN R+I + +F+KIAG + V +L + ++Q+++R++GLP+T T E+L FF V GI V GDAFV+F E AQ A +G RY+E+F ST E+ QV+
Sbjct: 9 LVVLFTTTAGANGSKLGSDEKEVIQLLWKVINLANKKV----------GELHEVTVRPDHLELTEECKEITRI-EADSLYVAPQLEQALQQFNQSVGNELNIGVGTSFCI--CTDGQLHIRQVLHPEASKKNILLPECFYSFFDLRKEFLKCCPGSSDTNELDVHAMASCILLSGAKSTRYRYGASEVDDMGDIIVTLISEPYNIFSLLISDVFLFHSSKL-------------EIIDDNTIIRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM--GN-RYIEVYKATGEDFLKIAGGTSNEVAQFLSK---ENQVIVRMRGLPFTATAEEVLAFF-GQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVL 411
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Xenopus
Match: atf1 (activating transcription factor 1 [Source:Xenbase;Acc:XB-GENE-971677]) HSP 1 Score: 136.346 bits (342), Expect = 1.127e-32 Identity = 108/399 (27.07%), Postives = 190/399 (47.62%), Query Frame = 3
Query: 660 DETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQNLDEISNFLQIEKPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
DE ++Q+ +++I+L+N + L + + PD + ++ +E+T + + S + +L+ AL + + + + + + + G L +R VLH E + +Y+ FD F KC +N L + M+ +S A ++ + F S K + I+ + ++ + + +++ I FF+GLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM GN R+I + +F+KIAG + V +L + ++Q+++R++GLP+T T E+L FF V GI V GDAFV+F E AQ A +G RY+E+F ST E+ QV+
Sbjct: 27 DEKEVIQLLWKVINLANKKV----------GELHEVTVRPDHLELTEECKEITRI-EADSLYVAPQLEQALQQFNQSVGNELNIGVGTSFCI--CTDGQLHIRQVLHPEA---SKKNILLPECFYSFFDLRKEFL--KCCPGSSDTNELDVH-----AMASCILLSGAFSDPERVNYKFESGTCSKL----------EIIDDNTIIRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM--GN-RYIEVYKATGEDFLKIAGGTSNEVAQFLSK---ENQVIVRMRGLPFTATAEEVLAFF-GQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVL 385
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Xenopus
Match: atf1 (activating transcription factor 1 [Source:Xenbase;Acc:XB-GENE-971677]) HSP 1 Score: 136.732 bits (343), Expect = 1.173e-32 Identity = 109/399 (27.32%), Postives = 189/399 (47.37%), Query Frame = 3
Query: 660 DETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQNLDEISNFLQIEKPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
DE ++Q+ +++I+L+N + L + + PD + ++ +E+T + + S + +L+ AL + + + + + + + G L +R VLH E + +Y+ FD F KC +N L + M+ +S A LFHS + + I+ + ++ + + +++ I FF+GLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM GN R+I + +F+KIAG + V +L + ++Q+++R++GLP+T T E+L FF V GI V GDAFV+F E AQ A +G RY+E+F ST E+ QV+
Sbjct: 27 DEKEVIQLLWKVINLANKKV----------GELHEVTVRPDHLELTEECKEITRI-EADSLYVAPQLEQALQQFNQSVGNELNIGVGTSFCI--CTDGQLHIRQVLHPEA---SKKNILLPECFYSFFDLRKEFL--KCCPGSSDTNELDVH-----AMASCILLSGAAFTDV---FLFHSSKL-------------EIIDDNTIIRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM--GN-RYIEVYKATGEDFLKIAGGTSNEVAQFLSK---ENQVIVRMRGLPFTATAEEVLAFF-GQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVL 379
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Xenopus
Match: atf1 (activating transcription factor 1 [Source:Xenbase;Acc:XB-GENE-971677]) HSP 1 Score: 135.191 bits (339), Expect = 4.456e-32 Identity = 112/408 (27.45%), Postives = 200/408 (49.02%), Query Frame = 3
Query: 660 DETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEV--SIFTSSKCQNLD--EISNFLQIEKPGGT---TMSIICYMSNAILQLTQ--LGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
DE ++Q+ +++I+L+N + L + + PD + ++ +E+T + + S + +L+ AL + + + + + + + G L +R VLH E +NI L +Y +++L E SS LD ++++L EK S + M + I+ L + F + ++ + I+ + ++ + + +++ I FF+GLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM GN R+I + +F+KIAG + V +L + ++Q+++R++GLP+T T E+L FF V GI V GDAFV+F E AQ A +G RY+E+F ST E+ QV+
Sbjct: 27 DEKEVIQLLWKVINLANKKV----------GELHEVTVRPDHLELTEECKEITRI-EADSLYVAPQLEQALQQFNQSVGNELNIGVGTSFCI--CTDGQLHIRQVLHPEASKKNILLPECFYSFFDLRKEFLKCCPGSSDTNELDVHAMASYLGFEKKSTRYRYGASEVDDMGDIIVTLISEPYNYKFSDPERVNYKFESGTCSKLEIIDDNTIIRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM--GN-RYIEVYKATGEDFLKIAGGTSNEVAQFLSK---ENQVIVRMRGLPFTATAEEVLAFF-GQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVL 414
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Xenopus
Match: atf1 (activating transcription factor 1 [Source:Xenbase;Acc:XB-GENE-971677]) HSP 1 Score: 133.265 bits (334), Expect = 1.546e-31 Identity = 106/373 (28.42%), Postives = 178/373 (47.72%), Query Frame = 3
Query: 738 LLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQNLDEISNFLQIEKPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
+LQ L + + PD + ++ +E+T + + S + +L+ AL + + + + + + + G L +R VLH E +NI L +Y FD F KC +N L + + ++ L LFHS + + I+ + ++ + + +++ I FF+GLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM GN R+I + +F+KIAG + V +L + ++Q+++R++GLP+T T E+L FF V GI V GDAFV+F E AQ A +G RY+E+F ST E+ QV+
Sbjct: 43 VLQVGELHEVTVRPDHLELTEECKEITRI-EADSLYVAPQLEQALQQFNQSVGNELNIGVGTSFCI--CTDGQLHIRQVLHPEASKKNILLPECFYS---FFDLRKEFL--KCCPGSSDTNELDVHAMASCILLSGAAFTDIFSLLISDVFLFHSSKL-------------EIIDDNTIIRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM--GN-RYIEVYKATGEDFLKIAGGTSNEVAQFLSK---ENQVIVRMRGLPFTATAEEVLAFF-GQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVL 387
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Mouse
Match: Esrp2 (epithelial splicing regulatory protein 2 [Source:MGI Symbol;Acc:MGI:1924661]) HSP 1 Score: 152.91 bits (385), Expect = 1.056e-37 Identity = 127/437 (29.06%), Postives = 214/437 (48.97%), Query Frame = 3
Query: 591 PSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQ--AIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVIL---GHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQNLD----EISNFLQIEKPGGT---TMSIICYMSNAILQLTQL--GHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKA-KNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
P L+ T G G DLG DET ++ + +Q+++ + Q + L+ +A++L S RE + L S+ S L L + ++ +V + + P +L G LR VLH E +N+ L + ++ +Y+L E + S C D ++ L +E + + M IL L + G LF V+K Y+ D ++ + V+ + + +++ + FF+GLNIA GG+A+ + ++GRR+ + LI+F D QRD+AL R KHHM R+I + EF+KIAG + V +L + +DQ+++R++GLP++ ++L F + V +G+ V+ G GDAF +F E +AQ A + KGM +G RY+E+F ST E+ QV+
Sbjct: 25 PEPQSLVVLFGATAGALGPDLGSDETDLILLVWQVVEPRSRQVGTLHKSLVRAEAAAL------------SPQCREASGL-SADSLARAESLDKVLQQFSQLVSGDVAL-----LGGGPYVLCTDGQQLLRQVLHPEASRKNLVLPDTFFSFYDLRREFHMQHPSTCSARDLTVGTMAQDLGLETDATEDDFGVWEVKTMVAVILHLLEGSNGQLFSKPEVVKQKYETGPCSKADVVDNETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHM---GVRYIEVYKATGEEFVKIAGGTSLEVARFLSR---EDQVILRLRGLPFSAGPTDVLGFL-GPECPVTGGADGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGM-LGKRYIELFRSTAAEVQQVL 435
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Mouse
Match: Esrp2 (epithelial splicing regulatory protein 2 [Source:MGI Symbol;Acc:MGI:1924661]) HSP 1 Score: 147.517 bits (371), Expect = 1.724e-36 Identity = 127/437 (29.06%), Postives = 214/437 (48.97%), Query Frame = 3
Query: 591 PSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQ--AIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVIL---GHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQNLD----EISNFLQIEKPGGT---TMSIICYMSNAILQLTQL--GHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKA-KNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
P L+ T G G DLG DET ++ + +Q+++ + Q + L+ +A++L S RE + L S+ S L L + ++ +V + + P +L G LR VLH E +N+ L + ++ +Y+L E + S C D ++ L +E + + M IL L + G LF V+K Y+ D ++ + V+ + + +++ + FF+GLNIA GG+A+ + ++GRR+ + LI+F D QRD+AL R KHHM R+I + EF+KIAG + V +L + +DQ+++R++GLP++ ++L F + V +G+ V+ G GDAF +F E +AQ A + KGM +G RY+E+F ST E+ QV+
Sbjct: 25 PEPQSLVVLFGATAGALGPDLGSDETDLILLVWQVVEPRSRQVGTLHKSLVRAEAAAL------------SPQCREASGL-SADSLARAESLDKVLQQFSQLVSGDVAL-----LGGGPYVLCTDGQQLLRQVLHPEASRKNLVLPDTFFSFYDLRREFHMQHPSTCSARDLTVGTMAQDLGLETDATEDDFGVWEVKTMVAVILHLLEGSNGQLFSKPEVVKQKYETGPCKA-DVVDNETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHM---GVRYIEVYKATGEEFVKIAGGTSLEVARFLSR---EDQVILRLRGLPFSAGPTDVLGFL-GPECPVTGGADGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGM-LGKRYIELFRSTAAEVQQVL 434
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Mouse
Match: Esrp1 (epithelial splicing regulatory protein 1 [Source:MGI Symbol;Acc:MGI:1917326]) HSP 1 Score: 144.821 bits (364), Expect = 1.726e-35 Identity = 119/440 (27.05%), Postives = 204/440 (46.36%), Query Frame = 3
Query: 585 MNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMT-----DLLSSPSSHSTFKL--QDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFT--SSKCQNLD-----EISNFLQIEKPGGTTMSIICYMSNAILQLTQ--LGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
M S L+ +T G G LG DE ++ + ++++DL+N + L + PD++ ++ +E T +L S+P + Q NE++ + + + D G L +R +LH E +N+ L +Y +++L E S LD E NF + + S + M N IL + H F + ++ + I+ V+ + + +++ I FF+GLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM +R+I + +F+KIAG + V +L + ++Q+++R++GLP+T T E++ FF + + GI V G GDAFV+F E AQ A +G RY+E+F ST E+ QV+
Sbjct: 1 MTASPDYLVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKV----------GQLHEVLVRPDQLELTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGTSFCLCTD----------GQLHIRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVAAMTESLNFEKSDSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDSTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM---GTRYIEVYKATGEDFLKIAGGTSNEVAQFLSK---ENQVIVRMRGLPFTATAEEVVAFFGQH-CPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVL 413 HSP 2 Score: 50.8322 bits (120), Expect = 8.436e-6 Identity = 28/89 (31.46%), Postives = 49/89 (55.06%), Query Frame = 3
Query: 1590 LIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVA-QKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
IR++GLPY T +IL+F +++ +G+ +V G +GDAF+ ++ A A+ T+ +RY+E+F + EMN V+
Sbjct: 446 CIRLRGLPYAATIEDILDFLGEFSTDIR--THGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVL 532
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Mouse
Match: Esrp1 (epithelial splicing regulatory protein 1 [Source:MGI Symbol;Acc:MGI:1917326]) HSP 1 Score: 145.591 bits (366), Expect = 1.873e-35 Identity = 119/440 (27.05%), Postives = 204/440 (46.36%), Query Frame = 3
Query: 585 MNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMT-----DLLSSPSSHSTFKL--QDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFT--SSKCQNLD-----EISNFLQIEKPGGTTMSIICYMSNAILQLTQ--LGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
M S L+ +T G G LG DE ++ + ++++DL+N + L + PD++ ++ +E T +L S+P + Q NE++ + + + D G L +R +LH E +N+ L +Y +++L E S LD E NF + + S + M N IL + H F + ++ + I+ V+ + + +++ I FF+GLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM +R+I + +F+KIAG + V +L + ++Q+++R++GLP+T T E++ FF + + GI V G GDAFV+F E AQ A +G RY+E+F ST E+ QV+
Sbjct: 1 MTASPDYLVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKV----------GQLHEVLVRPDQLELTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGTSFCLCTD----------GQLHIRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVAAMTESLNFEKSDSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDSTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM---GTRYIEVYKATGEDFLKIAGGTSNEVAQFLSK---ENQVIVRMRGLPFTATAEEVVAFFGQH-CPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVL 413
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Mouse
Match: Esrp1 (epithelial splicing regulatory protein 1 [Source:MGI Symbol;Acc:MGI:1917326]) HSP 1 Score: 145.206 bits (365), Expect = 2.389e-35 Identity = 119/440 (27.05%), Postives = 204/440 (46.36%), Query Frame = 3
Query: 585 MNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMT-----DLLSSPSSHSTFKL--QDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFT--SSKCQNLD-----EISNFLQIEKPGGTTMSIICYMSNAILQLTQ--LGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
M S L+ +T G G LG DE ++ + ++++DL+N + L + PD++ ++ +E T +L S+P + Q NE++ + + + D G L +R +LH E +N+ L +Y +++L E S LD E NF + + S + M N IL + H F + ++ + I+ V+ + + +++ I FF+GLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM +R+I + +F+KIAG + V +L + ++Q+++R++GLP+T T E++ FF + + GI V G GDAFV+F E AQ A +G RY+E+F ST E+ QV+
Sbjct: 1 MTASPDYLVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKV----------GQLHEVLVRPDQLELTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGTSFCLCTD----------GQLHIRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVAAMTESLNFEKSDSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDSTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM---GTRYIEVYKATGEDFLKIAGGTSNEVAQFLSK---ENQVIVRMRGLPFTATAEEVVAFFGQH-CPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVL 413
BLAST of Epithelial splicing regulatory protein 1/2 vs. UniProt/SwissProt
Match: sp|Q9BJZ5|FUSIL_DROME (RNA-binding protein fusilli OS=Drosophila melanogaster OX=7227 GN=fus PE=2 SV=1) HSP 1 Score: 171.4 bits (433), Expect = 2.655e-42 Identity = 135/475 (28.42%), Postives = 225/475 (47.37%), Query Frame = 3
Query: 606 LMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQ------------------------ASS--LLDPSANPDKIHISVPAREMTD----LLSSPSSHSTFK-LQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQN----LDEISNFLQI----------EKPGGTTMSII----CY------MSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSND---VEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
+++ ++ TCG G+ LG DE I+ + F L+++S Q +G K IL++ ASS L AN S + + +L + + K L +A+ E D+++ L E+ V G LPLR LHRE +++ L Y+ + +L E + S + ++ LQ E G +S + Y M I L Q GH F + ++ +P + ++DE++ + ++ + + +++ I FFRGLN+A GG+A+ +S GRR+ + LI+F + RD+AL R KHH+ +R+I + +F+ IAG + + +L + Q++IR++GLPY T ++L+FF + D V + G+ V+K G GDAFV+F NE A KA +IG RY+E+F ST E+ QV+
Sbjct: 7 VVSLYIATCGQNGSGLGSDEKEIILLVFVLLEVSTGQIVGTKQILVRPDGYFIKDRTISSSSDNSSVTNNTASSPPLAIGDANNGSGSTSGNGNSLENGSELILPIAEAQAAGKPLSEAIEEFDAYLRSLSL----HDTEIKLVTDGQLPLRQCLHREASAKDVELPAYYNRFSDLRKEFLRYKSGDLARALVPVKDVKKMLQAPTLPMPQSIAEMLGELNISSVEDNDFYIRESRDMVTVIQTLLQAGHKFAANELVNLVLEPGICSIDDEVDGNCIVRARGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHI---GTRYIEVYRASGEDFLAIAGGASNEAQAFLSK---GAQVIIRMRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQRYIELFRSTTAEVQQVL 471
BLAST of Epithelial splicing regulatory protein 1/2 vs. UniProt/SwissProt
Match: sp|B2RYJ8|ESRP2_RAT (Epithelial splicing regulatory protein 2 OS=Rattus norvegicus OX=10116 GN=Esrp2 PE=2 SV=1) HSP 1 Score: 155.992 bits (393), Expect = 6.980e-38 Identity = 129/437 (29.52%), Postives = 217/437 (49.66%), Query Frame = 3
Query: 591 PSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQ--AIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVIL---GHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQNLD----EISNFLQIEKPGGT---TMSIICYMSNAILQLTQL--GHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKA-KNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
P L+ T G G DLG DET ++ + +Q+++ + Q + L+ +A++L S RE + L S+ S L L + ++ +V + + P +L G LR VLH E +N+ L + ++ +Y+L E + S C D ++ L +E + + M IL L + GHLF V+K Y+ D ++ + V+ + + +++ + FF+GLNIA GG+A+ + ++GRR+ + LI+FED QRD+AL R KHHM R+I + EF+KIAG + V +L + +DQ+++R++GLP++ ++L+F + V +G+ V+ G GDAF +F E +AQ A + KGM +G RY+E+F ST E+ QV+
Sbjct: 25 PEPQSLVVLFGATAGALGPDLGSDETDLILLVWQVVEPRSRQVGTLHKSLVRAEAAAL------------SPQCREASGL-SADSLARAESLDKVLQQFSQLVSGDVAL-----LGGGPYVLCTDGQQLLRQVLHPEASRKNLVLPDTFFSFYDLRREFHVQHPSTCSARDLTVGTMAQDLGLETDATEDDFGVWEVKTMVAVILHLLEGPNGHLFSKPEVVKQKYETGPCKA-DVVDNETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFEDSEQRDLALQRHKHHM---GVRYIEVYKATGEEFVKIAGGTSLEVARFLSR---EDQVILRLRGLPFSAGPADVLDFL-GPECPVTGGVDGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGM-LGKRYIELFRSTAAEVQQVL 434
BLAST of Epithelial splicing regulatory protein 1/2 vs. UniProt/SwissProt
Match: sp|Q5ZLR4|ESRP2_CHICK (Epithelial splicing regulatory protein 2 OS=Gallus gallus OX=9031 GN=ESRP2 PE=2 SV=1) HSP 1 Score: 154.066 bits (388), Expect = 2.691e-37 Identity = 123/441 (27.89%), Postives = 217/441 (49.21%), Query Frame = 3
Query: 606 LMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEV-SIFTSS---KCQNLDEISNFL-----QIEKPGG-----TTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKP 1883
L+ T G G LG DE ++ + +Q++DL + + +L D + +S RE++ L + + L L + ++ ++ V + + G L +R VLH ET +N L++ +Y +Y+L E + + SS K Q + ++ +L + E+ G T ++II M + H+F +K Y+ ++ ++ + V+ + + +++ I FF+GLNIA GG+A+ + ++GRR+ + L++F + QRD+AL R KHHM SR+I + EF+KIAG + V +L + ++Q++IR++GLP+T T+ ++L F + V G+ V+ G GDAFV+F E AQ A +G RY+E+F ST E+ QV++ + P P
Sbjct: 9 LVVLFGATAGAYGAKLGSDERELILLVWQVVDLPSKKV----------GTLHKSLVKADNLELSDQCREVSGLTAEGLGKAE-PLDRVLQQFIQLVSSDLKVFGRNSYTLCSD--GQLLIRQVLHPETSKKNFLLSDCFYSFYDLRKEFHTCYPSSAAVKDQTIKTMAEYLGLGTDEAEEDFGVWQVKTMVAIIFSMLS-----ENCDHIFTDPETVKYKYETGPCSKSETVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFVNSEQRDLALERHKHHM---GSRYIEVYKATGEEFLKIAGGTSNEVAQFLSK---ENQVIIRMRGLPFTATQEDVLGFL-GPECPVTGGKEGLLFVKYPDGRPTGDAFVLFSCEEYAQNALKKHKEILGKRYIELFRSTAAEVQQVLNRYMSTPLIP 424
BLAST of Epithelial splicing regulatory protein 1/2 vs. UniProt/SwissProt
Match: sp|Q8K0G8|ESRP2_MOUSE (Epithelial splicing regulatory protein 2 OS=Mus musculus OX=10090 GN=Esrp2 PE=1 SV=1) HSP 1 Score: 152.91 bits (385), Expect = 7.387e-37 Identity = 127/437 (29.06%), Postives = 214/437 (48.97%), Query Frame = 3
Query: 591 PSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQ--AIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVIL---GHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQNLD----EISNFLQIEKPGGT---TMSIICYMSNAILQLTQL--GHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKA-KNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
P L+ T G G DLG DET ++ + +Q+++ + Q + L+ +A++L S RE + L S+ S L L + ++ +V + + P +L G LR VLH E +N+ L + ++ +Y+L E + S C D ++ L +E + + M IL L + G LF V+K Y+ D ++ + V+ + + +++ + FF+GLNIA GG+A+ + ++GRR+ + LI+F D QRD+AL R KHHM R+I + EF+KIAG + V +L + +DQ+++R++GLP++ ++L F + V +G+ V+ G GDAF +F E +AQ A + KGM +G RY+E+F ST E+ QV+
Sbjct: 25 PEPQSLVVLFGATAGALGPDLGSDETDLILLVWQVVEPRSRQVGTLHKSLVRAEAAAL------------SPQCREASGL-SADSLARAESLDKVLQQFSQLVSGDVAL-----LGGGPYVLCTDGQQLLRQVLHPEASRKNLVLPDTFFSFYDLRREFHMQHPSTCSARDLTVGTMAQDLGLETDATEDDFGVWEVKTMVAVILHLLEGSNGQLFSKPEVVKQKYETGPCSKADVVDNETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHM---GVRYIEVYKATGEEFVKIAGGTSLEVARFLSR---EDQVILRLRGLPFSAGPTDVLGFL-GPECPVTGGADGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGM-LGKRYIELFRSTAAEVQQVL 435
BLAST of Epithelial splicing regulatory protein 1/2 vs. UniProt/SwissProt
Match: sp|A1L1G1|ESRP1_DANRE (Epithelial splicing regulatory protein 1 OS=Danio rerio OX=7955 GN=esrp1 PE=2 SV=1) HSP 1 Score: 150.984 bits (380), Expect = 2.373e-36 Identity = 130/478 (27.20%), Postives = 229/478 (47.91%), Query Frame = 3
Query: 651 LGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQ----NLDEISNFLQIEKPGGTTMSIICYMSNAILQLTQL---------GHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI---SAAQNIPFKPKQNKQITKPTDSVNQENIKSSQKAVMSGTVTKYIPMEASDNDFVRYLADH 2033
LG DE I+Q+ +Q++DL+ +A Q + LL PD I +S +E++ L + + L+ A+++++ + V T + G L +R VLH E +NI L + ++ +++L E S+ + NL +++ L + S+ + + + Q+ + H F + ++ + ++ + V+ + + +++ I FFRGLNIA GG A+ + ++GRR+ + L++FE + RD+AL R KHHM R+I + +F+KIAG + V +L + ++QI++R++GLP+ T ++L FF S V GI V+ G GDAFV+F E AQ A +G RY+E+F ST E+ QV+ S+A IP P + P V Q ++ V + +P +AS D + +L ++
Sbjct: 23 LGSDEKEIVQLVWQVVDLATKKAG-------QVNELL---VKPDHIELSEECQELSGL-TDEALTPVDPLEVAIDQLNQRLCAEVDTGAGNTFYL--CTDGQLHVRQVLHPEASSKNILLPDCFFSFFDLRKEFKKEFPSEVKLKDLNLQVMADHLNV----AVDSSLHAFTAYKVQQMVDIVLALISEPTCHEFTFPEKVNEKFETGTCSKMERVDDNTVIRARGLPWQSSDQDIARFFRGLNIAKGGAALCLNAQGRRNGEALVRFESEEHRDLALQRHKHHM---GGRYIEVYKATGEDFLKIAGGTSNEVASFLSR---ENQIIVRMRGLPFNATAEQVLQFF-SPACPVTDGSEGILFVRFPDGRPTGDAFVLFSCEEHAQNALKKHKDMLGKRYIELFKSTAAEVQQVLNKYSSAPLIPVAPSPILSVVAPPTFVPQ---TAAVPGVRDCVRLRGLPYDASIQDILVFLGEY 473
BLAST of Epithelial splicing regulatory protein 1/2 vs. TrEMBL
Match: A0A267EB47 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017860g1 PE=4 SV=1) HSP 1 Score: 222.631 bits (566), Expect = 7.928e-57 Identity = 150/457 (32.82%), Postives = 231/457 (50.55%), Query Frame = 3
Query: 561 NDINKKLKMNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIH-----------ISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQNLDEISNF------LQIE---KPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQN 1868
N N + P L+A HL TCG QG ++G DE I + + + D+ +N+ I+ L+ P NP + IS R T L S+ S HS L+ L E+D F+ + + V+ G P+R V H ET + I+L + Y Y FD F + D I + L+++ P T I MS I +L GH F + Y P + D ++ + V+ + + ++ I FFRGLNI+ GGIA+++S+ GRR+ + LI+F+ + RDIAL + +HHM+ R+I + R+F+ +AG + + + +L ++ Q L+R++GLPYTV+ EIL+FF+ + VQF G+ V G GDAFVIFENE +A++A IGNRY+E+F STP E+NQV+ + +N
Sbjct: 68 NPGNSNSSIMPQPDYLVALHLTTCGKQGEEIGTDEAPICLIAYLIHDVRHNK------IIAVEQHLVKPQVNPGQTGSDSSEEDGLATISEECRSETGL-SADSFHSASYLESVLEEMDKFLRNKGIHPESGGKTFTLVLEGQHPMRLVFHPETCSKKISLEQFPYFYS-FFDLRKEFLKGRNSEPDTIVSLKDMLDSLEMQFDNSPDYGTRQCIA-MSRVISRLLNDGHTFKEPEKVNQFYYPAIVRKTDTVDDESVVRARGLPWQATDADIHKFFRGLNISAGGIALVLSKVGRRNGEALIRFDSQEHRDIALKKHRHHMQ---QRYIEVYRATGRDFVAVAGADTKEGENFLAKLTEPTQSLVRMRGLPYTVSADEILDFFRKAECPVQFDSEGVLFVNHKDGRATGDAFVIFENEILAERALQNHRQHIGNRYIELFKSTPAEVNQVLCSFKN 512
BLAST of Epithelial splicing regulatory protein 1/2 vs. TrEMBL
Match: A0A267FI41 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig034309g1 PE=4 SV=1) HSP 1 Score: 222.631 bits (566), Expect = 8.155e-57 Identity = 150/457 (32.82%), Postives = 231/457 (50.55%), Query Frame = 3
Query: 561 NDINKKLKMNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIH-----------ISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQNLDEISNF------LQIE---KPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQN 1868
N N + P L+A HL TCG QG ++G DE I + + + D+ +N+ I+ L+ P NP + IS R T L S+ S HS L+ L E+D F+ + + V+ G P+R V H ET + I+L + Y Y FD F + D I + L+++ P T I MS I +L GH F + Y P + D ++ + V+ + + ++ I FFRGLNI+ GGIA+++S+ GRR+ + LI+F+ + RDIAL + +HHM+ R+I + R+F+ +AG + + + +L ++ Q L+R++GLPYTV+ EIL+FF+ + VQF G+ V G GDAFVIFENE +A++A IGNRY+E+F STP E+NQV+ + +N
Sbjct: 68 NPGNSNSSIMPQPDYLVALHLTTCGKQGEEIGTDEAPICLIAYLIHDVRHNK------IIAVEQHLVKPQVNPGQTGSDNSEEDGLATISEECRSETGL-SADSFHSASYLESVLEEMDKFLRNKGIHPESGGKTFTLVLEGQHPMRLVFHPETCSKKISLEQFPYFYS-FFDLRKEFLKGRNSEPDTIVSLKDMLDSLEMQFDNSPDYGTRQCIA-MSRVISRLLNDGHTFKEPEKVNQFYYPAIVRKTDTVDDESVVRARGLPWQATDADIHKFFRGLNISAGGIALVLSKVGRRNGEALIRFDSQEHRDIALKKHRHHMQ---QRYIEVYRATGRDFVAVAGADTKEGENFLAKLTEPTQSLVRMRGLPYTVSADEILDFFRKAECPVQFDSEGVLFVNHKDGRATGDAFVIFENEILAERALQNHRQHIGNRYIELFKSTPAEVNQVLCSFKN 512
BLAST of Epithelial splicing regulatory protein 1/2 vs. TrEMBL
Match: J9JKD1 (RRM domain-containing protein OS=Acyrthosiphon pisum OX=7029 GN=100159234 PE=4 SV=2) HSP 1 Score: 203.371 bits (516), Expect = 2.272e-50 Identity = 155/562 (27.58%), Postives = 285/562 (50.71%), Query Frame = 3
Query: 564 DINKKLK---MNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSAN--PDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSS-KCQNLDEIS---NFLQI--EKPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMS-EGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSND--VEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKPK---QNKQITKPTDSVNQENIKSS------------QKAVMSGTVTKYI-----PMEASDNDFVRYLADHRGLCLLSSRSHLYSPIGYISYVAFFKNSSDASATIKAL 2147
D+ K +K M + L A ++ T G QGN LG DE I+ + + ++D++ N +G + L++ + + D + N D++ + E S LQDA+++ D+++ L + QT V G LP+R LHRE+ ++I L Y+ +++L + S F ++ + Q + I+ N+L+I E ++ + M N + +L GH F+S +++ +P + N+E++ + V+ + + +++ I FFRGLNIA GG+A+ +S GRR+ + +++F ++ RD+A+ R KHH+ SR+I + + +F+ +AG + + +L + Q+++R++GLPY T +++ FF++ + V +G+ V+K G GDAFV+F +E A KA + IG RY+E+F ST E+ QV++ A + + N IT P + N + Q + SGT I P EA+ + +L +H + +Y+ +G+ S AF + +++ SA A+
Sbjct: 29 DVCKSIKVTNMRAATPYLCALYVATAGHQGNLLGSDEQEIVLLIYVVVDMTTNTVVGIQQYLVKPTEV-DQNENMLSDQVTSDIGITEKM------VKTSGIPLQDAIDKFDTYVKS--LNIEPQTPMFRIVTDGQLPIRQCLHRESSIKDIELPEYYNVFHDLRKDFSKFYNAPQDQTFNSITDLVNYLEITHEIDSQFYVAEVKDMVNIVQRLIADGHTFNSPEIVQLKLEPGICWKNEEVDNNCVVRARGLPWQSSDQDIAKFFRGLNIAKGGVALCLSAHGRRNGEAVVRFVNQEHRDMAMKRHKHHI---GSRYIEVYKANGEDFINVAGGNSSEAQTFLTK---GAQVIVRMRGLPYDCTAKDVITFFENGEQTCSVMDGEDGVLFVKKPDGRATGDAFVLFADEDDAPKALSKHRDLIGTRYIELFRSTTAEVQQVLNRAMDPSVRSTASDSNGNITTPVTTTAGVNNSPTALLGHVPLLPLPQHVITSGTRKDCIRLRGLPYEANVEHILEFLGEHSKNIVFQGVHMVYNSVGHASGEAFIQMNNEGSAAQAAM 575
BLAST of Epithelial splicing regulatory protein 1/2 vs. TrEMBL
Match: A0A5E4N7I8 (RRM domain-containing protein OS=Cinara cedri OX=506608 GN=CINCED_3A017892 PE=4 SV=1) HSP 1 Score: 200.675 bits (509), Expect = 4.860e-50 Identity = 152/564 (26.95%), Postives = 284/564 (50.35%), Query Frame = 3
Query: 549 SELNNDINKKLKMNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSAN--PDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQ----NLDEISNFLQI--EKPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMS-EGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSND--VEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKPK---QNKQITKPTDSVNQENIKSS------------QKAVMSGTVTKYI-----PMEASDNDFVRYLADHRGLCLLSSRSHLYSPIGYISYVAFFKNSSDASATIKAL 2147
S N++ K M + L A ++ T G QGN LG DE I+ + + ++D++ N +G + L++ + + D + N D++ + E S LQDA+ + D+++ L + Q V G LP+R LHRE ++I L Y+ +++L + S F ++ + ++ ++ N+L+I E ++ + M N + +L GH F+S +++ +P + N+E++ + V+ + + +++ I FFRGLNIA GG+A+ +S GRR+ + +++F ++ RD+A+ R KHH+ SR+I + + +F+ +AG + + +L + Q+++R++GLPY T +++ FF++ + V + +G+ V+K+ G GDAFV+F +E A KA + IG RY+E+F ST E+ QV++ A + + N IT P + N + Q + SGT I P EA+ + +L +H + +Y+ +G+ S AF + +++ SA A+
Sbjct: 31 STCNSNSVKVGNMRAATPYLCALYVATAGYQGNLLGSDEQEIVLLIYVVVDMTTNAIVGIQQYLVKPTEV-DQNENMLSDQVTSDIGITEKM------VKTSGIPLQDAIEKFDTYVKS--LNIEPQAPMFRIVTDGQLPIRQCLHREASIKDIELPEYYNVFHDLRKDFSKFYNAPQEQTFNSITDLVNYLEITHEIDSQFYVAEVKDMVNIVQRLIADGHTFNSPEIVQLKLEPGICWKNEEVDNNCVVRARGLPWQSSDQDIAKFFRGLNIAKGGVALCLSAHGRRNGEAVVRFVNQEHRDMAMKRHKHHI---GSRYIEVYKANGEDFINVAGGNSSEAQAFLTK---GAQVIMRMRGLPYDCTAKDVITFFENGEQTCSVMDAEDGVLFVKKTDGRATGDAFVLFADEDDASKALSKHRDLIGTRYIELFRSTTAEVQQVLNRAMDPTVRSTVSDSNGNITTPVTTTAGVNNSPTAILGHMPLLPLPQHVITSGTRKDCIRLRGLPYEANVEHILEFLGEHSKNIVFQGVHMVYNSVGHASGEAFIQMNNEGSAAQAAM 579
BLAST of Epithelial splicing regulatory protein 1/2 vs. TrEMBL
Match: A0A0V0J5S0 (RNA-binding protein fusilli (Fragment) OS=Schistocephalus solidus OX=70667 GN=FUSIL PE=4 SV=1) HSP 1 Score: 201.83 bits (512), Expect = 9.092e-50 Identity = 109/273 (39.93%), Postives = 161/273 (58.97%), Query Frame = 3
Query: 1065 SSKCQNLD----EISNFLQIEKPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQN 1868
SS C ++D E+ N L KPG M ++ L++T G + I Y+P + V DE+E D+V+ + + ++ + I FFRGLNIA GGIA+++++ GRR+ + LI+F D+ QRD+AL + KHHM N R+I I + +F+ +AG E E + +L++ Q LIR++GLPYTVT +IL FF + + EVQF G+ V + G GDAF +F N+ AQKA IGNRY+E+F STP E+NQV++ N
Sbjct: 457 SSCCTHMDYPGDEMRNSL---KPGYWPMEYCRNLAKLCLKMTLDGVEWKFYECIFAYYQPGIVKVTDEVEDDVVVRARGLPWQATDSDIQFFFRGLNIAPGGIALVLNKSGRRNGEALIRFTDREQRDLALRKHKHHM---NQRYIEIYMAQGSDFISVAGGETEEAEKFLQKFTEPSQALIRMRGLPYTVTAEQILEFFSNANCEVQFGEEGVLFVNRHDGRATGDAFALFANDHEAQKALKNHRQHIGNRYIELFRSTPAEVNQVMNVVLN 723
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Cavefish
Match: esrp1 (epithelial splicing regulatory protein 1 [Source:NCBI gene;Acc:103047742]) HSP 1 Score: 162.54 bits (410), Expect = 5.587e-41 Identity = 132/505 (26.14%), Postives = 240/505 (47.52%), Query Frame = 3
Query: 579 LKMNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQ----NLDEISNFLQIEKPGGTTMSIICYMSNAILQLTQLG---------HLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKPKQNKQITKPTDSVNQENIKSSQKAVMSGTVT------KYIPMEASDNDFVRYLADH 2033
+ +NP +L F TCG G LG DET +Q+ +Q+++L + +L++ P+ + +S E++ + + S S L++ALN+ + + ++ D G L LR VLH E +N+ L ++ +++L E S+ +L ++++L + + + + + I Q++ + H+F + ++ + I+ + V+ + + +++ + FFRGLNIA GG A+ + ++GRR+ + L++FE + RD+AL R KHHM SR+I + +F+KIAG + V +L + ++Q+++R++GLP+T T ++L FF S V GI V+ G GDAFV+F E A+ A +G RY+E+F ST E+ QV++ + P P I V Q S A+ + T + +P +AS D + +L ++
Sbjct: 1 MTVNPENLVL--FFTTTCGASGELLGSDETEAVQLVWQVLNLVTKKPGRVNEVLVK----------PESLCVSEECVEVSGVTTEALS-SAAPLEEALNQFNERLCSE--INTDAANSFCLCTDGQLHLRQVLHPEASNKNVLLPECFFSFFDLRKEFKKCFPSEADHKELDLKFMTDYLNLSEDSSDQV----FTAQKIHQMSSIAQALISEPTCHVFSCPEKVNEKFETGTCSKMERIDDNTVIRARGLPWQSSDQDVARFFRGLNIAKGGAALCLNAQGRRNGEALVRFESEEHRDLALQRHKHHM---GSRYIEVYKATGEDFLKIAGGTSNEVANFLSR---ENQVIVRMRGLPFTATAEQVLQFF-SPSCPVTDDGEGILFVRFPDGRPTGDAFVLFSCEEYAENALKKHKEILGKRYIELFRSTAAEVQQVLNKYSSAPLIPVAPSPILP---IVPQPTFVPSPAAIAAVVGTRDCLRLRGLPYDASVQDILLFLGEY 476
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Cavefish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:103029380]) HSP 1 Score: 141.354 bits (355), Expect = 3.430e-34 Identity = 77/231 (33.33%), Postives = 128/231 (55.41%), Query Frame = 3
Query: 1188 HLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPF 1877
H F S +K ++ + ++ + V+ + + +++ I FF+GLNIA GG+A+ + ++GRR+ + L++F + RD+AL R KHHM SR+I + EF+KIAG + V +L + ++Q++IR++GLP+T T+ ++L F D V G+ V+ G GDAFV+F E AQ A +G RY+E+F ST E+ QV++ + P
Sbjct: 197 HKFSSLEPVKYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALERHKHHM---GSRYIEVYKATGEEFLKIAGGTSNEVAQFLSK---ENQVIIRMRGLPFTATQQDVLGFL-GPDSPVTDGTEGLLFVKFPDGRPTGDAFVLFACEQYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPL 420
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Cavefish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:103029380]) HSP 1 Score: 141.354 bits (355), Expect = 3.552e-34 Identity = 77/231 (33.33%), Postives = 128/231 (55.41%), Query Frame = 3
Query: 1188 HLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPF 1877
H F S +K ++ + ++ + V+ + + +++ I FF+GLNIA GG+A+ + ++GRR+ + L++F + RD+AL R KHHM SR+I + EF+KIAG + V +L + ++Q++IR++GLP+T T+ ++L F D V G+ V+ G GDAFV+F E AQ A +G RY+E+F ST E+ QV++ + P
Sbjct: 197 HKFSSLEPVKYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALERHKHHM---GSRYIEVYKATGEEFLKIAGGTSNEVAQFLSK---ENQVIIRMRGLPFTATQQDVLGFL-GPDSPVTDGTEGLLFVKFPDGRPTGDAFVLFACEQYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPL 420
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Cavefish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:103029380]) HSP 1 Score: 141.354 bits (355), Expect = 3.552e-34 Identity = 77/231 (33.33%), Postives = 128/231 (55.41%), Query Frame = 3
Query: 1188 HLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPF 1877
H F S +K ++ + ++ + V+ + + +++ I FF+GLNIA GG+A+ + ++GRR+ + L++F + RD+AL R KHHM SR+I + EF+KIAG + V +L + ++Q++IR++GLP+T T+ ++L F D V G+ V+ G GDAFV+F E AQ A +G RY+E+F ST E+ QV++ + P
Sbjct: 197 HKFSSLEPVKYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALERHKHHM---GSRYIEVYKATGEEFLKIAGGTSNEVAQFLSK---ENQVIIRMRGLPFTATQQDVLGFL-GPDSPVTDGTEGLLFVKFPDGRPTGDAFVLFACEQYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPL 420
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Cavefish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:103029380]) HSP 1 Score: 141.354 bits (355), Expect = 4.176e-34 Identity = 77/231 (33.33%), Postives = 128/231 (55.41%), Query Frame = 3
Query: 1188 HLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPF 1877
H F S +K ++ + ++ + V+ + + +++ I FF+GLNIA GG+A+ + ++GRR+ + L++F + RD+AL R KHHM SR+I + EF+KIAG + V +L + ++Q++IR++GLP+T T+ ++L F D V G+ V+ G GDAFV+F E AQ A +G RY+E+F ST E+ QV++ + P
Sbjct: 197 HKFSSLEPVKYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALERHKHHM---GSRYIEVYKATGEEFLKIAGGTSNEVAQFLSK---ENQVIIRMRGLPFTATQQDVLGFL-GPDSPVTDGTEGLLFVKFPDGRPTGDAFVLFACEQYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPL 420
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Sea Lamprey
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:572992]) HSP 1 Score: 135.576 bits (340), Expect = 2.603e-33 Identity = 74/215 (34.42%), Postives = 118/215 (54.88%), Query Frame = 3
Query: 1242 HVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKP 1883
H N + D V+ ++ + +++ I FF+GLNIA GGIA+ ++ GRR+ + L+ +D+ QRD+AL R KHHM SR+I + + EF KIA + V +L + + Q+++R++GLP+ ++L FF + V G+ V+ G GDAFV+F E A A +G RY+E+F ST E+ QV++ + P P
Sbjct: 127 HYNS-VHGDTVVRVRGLPWQSSDQDIALFFKGLNIAKGGIALCLNPLGRRNGEALVMLQDEQQRDLALSRHKHHM---GSRYIEVYRSSAEEFSKIAVGASSEVSQFLAR---EGQVIVRMRGLPFAAAPDDVLAFFGAA-CPVTAGRQGLLFVRHPDGRPTGDAFVLFAGEECAAAALAKHRHMLGKRYIELFRSTAAELQQVLNRVMSTPLLP 333
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Sea Lamprey
Match: HNRNPH1 (heterogeneous nuclear ribonucleoprotein H1 [Source:HGNC Symbol;Acc:HGNC:5041]) HSP 1 Score: 73.1738 bits (178), Expect = 1.074e-13 Identity = 57/200 (28.50%), Postives = 94/200 (47.00%), Query Frame = 3
Query: 1251 DEIEPDIVLMIKPIDYKTPINQIIPFFRG---LNIADGGIAVIMSEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEM 1841
DE+ V+ ++ + + ++I F G +N ADG EGR S + ++ E + D AL RD +M R+I + E + N+ V L + + + +R++GLP++ +K EI FF ++ NGI L G G+AFV F ++ A+KA IG+RY+E+F S E+
Sbjct: 5 DEVVEGFVVRLRGLPWSCSSEEVIKFLSGCAIVNSADGVHFTNSREGRPSGEAFVELESEEDLDRALERDHKNM---GHRYIEVFRSKLSELNWVL---NQQNPVALPE-SGEAEGCVRLRGLPFSCSKEEIAQFFTG----LEIVPNGITLPVDYQGRSTGEAFVQFASQEAAEKALGKHKERIGHRYIEVFKSNRGEV 193 HSP 2 Score: 51.9878 bits (123), Expect = 5.399e-7 Identity = 26/94 (27.66%), Postives = 49/94 (52.13%), Query Frame = 3
Query: 1572 ETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
E + ++R++GLP++ + E++ F + S +G+ G +G+AFV E+E +A +G+RY+E+F S E+N V+
Sbjct: 6 EVVEGFVVRLRGLPWSCSSEEVIKFLSG--CAIVNSADGVHFTNSREGRPSGEAFVELESEEDLDRALERDHKNMGHRYIEVFRSKLSELNWVL 97
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Nematostella
Match: EDO47286 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMK7]) HSP 1 Score: 125.561 bits (314), Expect = 2.430e-31 Identity = 65/199 (32.66%), Postives = 115/199 (57.79%), Query Frame = 3
Query: 1266 DIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMS-EGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISA 1859
D VL + + ++ + FFRGLNI GGIA ++ +GRR+ + I+FE+ RD+AL R K H+ +R+I + +++F++I + + + T +++IR++GLP++ +++ FF +DV V GI +V+ +G+ GDAFV+FE E + A +G+RY+E+F S+ E+ QV+S+
Sbjct: 10 DTVLRARGLPWQASDQDVANFFRGLNIPRGGIAFCLNMQGRRNGEAFIRFENGDHRDLALRRHKMHL---GTRYIEVYKASAQDFLRIV----RGMSIAANFVSTNAEVIIRMRGLPFSTKAADVVRFF-GDDVPVYRGEGGILMVRGRNGKATGDAFVLFETEEHGRAALKKHREVLGSRYVELFRSSQSEVQQVLSS 200 HSP 2 Score: 51.2174 bits (121), Expect = 1.010e-6 Identity = 24/93 (25.81%), Postives = 46/93 (49.46%), Query Frame = 3
Query: 1581 DQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISA 1859
D ++R +GLP+ + ++ NFF+ ++ GI G NG+AF+ FEN A M +G RY+E++ ++ + +++
Sbjct: 9 DDTVLRARGLPWQASDQDVANFFRGLNI----PRGGIAFCLNMQGRRNGEAFIRFENGDHRDLALRRHKMHLGTRYIEVYKASAQDFLRIVRG 97 HSP 3 Score: 50.0618 bits (118), Expect = 2.481e-6 Identity = 26/92 (28.26%), Postives = 53/92 (57.61%), Query Frame = 3
Query: 1590 LIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFV-IFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAA 1862
+R++GLP++ T ++L+F K + V + G+ +V + G +GDA+V + + A A L +G RY+E+F + +++ VI+++
Sbjct: 247 CLRLRGLPFSATVQDVLDFLKEHAAYV--APGGVHMVYNTQGRPSGDAYVQLLSPDFAAAAANELHKHHMGERYIEVFPCSNSDISAVIASS 336
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Nematostella
Match: EDO37823 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEP3]) HSP 1 Score: 63.5438 bits (153), Expect = 1.354e-10 Identity = 48/200 (24.00%), Postives = 89/200 (44.50%), Query Frame = 3
Query: 1266 DIVLMIKPIDYKTPINQIIPFFRGLNIADG---GIAVIMS-EGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
+ V+ + + + I FF+ NI G G+ +GR S + ++F + + AL + HM R+I + + E + +K + + +++++GLPY +K EI FF ++ NGI + G+ G+ FV F + +A +A IG+RY+EIF S+ ++ V+
Sbjct: 4 ECVVRARGLPWSATPEDIQNFFKDCNIVGGPQNGVHFTFGIDGRPSGECFVQFVSEKDVEKALEMNNEHM---GKRYIEVFRSKAEEMEWV-------IKRMGPPSDRDQEAVVKLRGLPYGCSKEEIAQFFTG----LEIVPNGITITLDEEGKTTGEGFVEFASPEIAGQAMQKHKEKIGHRYIEIFKSSKSDIKYVL 189 HSP 2 Score: 59.3066 bits (142), Expect = 3.158e-9 Identity = 31/91 (34.07%), Postives = 50/91 (54.95%), Query Frame = 3
Query: 1581 DQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
++ ++R +GLP++ T +I NFFK ++ V NG+ G +G+ FV F +E +KA + +G RY+E+F S EM VI
Sbjct: 3 NECVVRARGLPWSATPEDIQNFFKDCNI-VGGPQNGVHFTFGIDGRPSGECFVQFVSEKDVEKALEMNNEHMGKRYIEVFRSKAEEMEWVI 92
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Medaka
Match: esrp1 (epithelial splicing regulatory protein 1 [Source:NCBI gene;Acc:101168983]) HSP 1 Score: 139.043 bits (349), Expect = 1.824e-33 Identity = 77/218 (35.32%), Postives = 122/218 (55.96%), Query Frame = 3
Query: 1248 NDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSND-----VEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKP 1883
+++ + V+ + + +++ I FFRGLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM GN R+I + +F+KIAG V ++L + +DQI++R++GLP+T T ++L FF D V +GI V+ G GDAFV+F E A A +G RY+E+F ST E+ QV++ + P P
Sbjct: 186 KEKVCDNTVIRARGLPWQSSDQDIARFFRGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM--GN-RYIEVYKATGEDFLKIAGGTTNEVAMFLSR---EDQIIVRMRGLPFTATYEQVLAFFSPKDGLNETCPVSGGKDGILFVRYPDGRPTGDAFVLFSCEEHALCALRKHKEILGKRYIELFKSTAAEVQQVLNRYSSTPLIP 397
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Medaka
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:101173047]) HSP 1 Score: 138.272 bits (347), Expect = 2.971e-33 Identity = 74/217 (34.10%), Postives = 122/217 (56.22%), Query Frame = 3
Query: 1233 IVFHVNDE-IEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPF 1877
++ H E ++ + V+ + + +++ I FF+GLNIA GG+A+ + ++GRR+ + L++F D RD+AL R KHHM R+I + EF+KIAG + V +L + ++Q++IR++GLP+T T E+L+F + V G+ V+ G GDAFV+F E Q A +G RY+E+F ST E+ QV++ + P
Sbjct: 168 LLAHCKTEPVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFIDSEHRDLALERHKHHM---GCRYIEVYKATGEEFLKIAGGTSNEVAQFLSK---ENQVIIRMRGLPFTATSQEVLSFL-GPESPVTDGAEGLLFVKYPDGRPTGDAFVLFSCEEYVQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPL 377 HSP 2 Score: 50.8322 bits (120), Expect = 7.445e-6 Identity = 30/97 (30.93%), Postives = 53/97 (54.64%), Query Frame = 3
Query: 1575 TQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEG----VAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
T + +R++GLPYT +IL F + V+++ +G+ +V G +GDAF+ ++ VAQK T+ +RY+E+F + EM+ V+
Sbjct: 400 TSTRDCVRLRGLPYTAGIEDILEFMGEHTVDIK--PHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHK---KTMKDRYVEVFQCSTEEMSIVL 491
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Medaka
Match: esrp1 (epithelial splicing regulatory protein 1 [Source:NCBI gene;Acc:101168983]) HSP 1 Score: 138.658 bits (348), Expect = 3.414e-33 Identity = 77/217 (35.48%), Postives = 122/217 (56.22%), Query Frame = 3
Query: 1251 DEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSND-----VEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKP 1883
+++ + V+ + + +++ I FFRGLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM GN R+I + +F+KIAG V ++L + +DQI++R++GLP+T T ++L FF D V +GI V+ G GDAFV+F E A A +G RY+E+F ST E+ QV++ + P P
Sbjct: 239 EKVCDNTVIRARGLPWQSSDQDIARFFRGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM--GN-RYIEVYKATGEDFLKIAGGTTNEVAMFLSR---EDQIIVRMRGLPFTATYEQVLAFFSPKDGLNETCPVSGGKDGILFVRYPDGRPTGDAFVLFSCEEHALCALRKHKEILGKRYIELFKSTAAEVQQVLNRYSSTPLIP 449
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Medaka
Match: esrp1 (epithelial splicing regulatory protein 1 [Source:NCBI gene;Acc:101168983]) HSP 1 Score: 138.272 bits (347), Expect = 3.604e-33 Identity = 77/217 (35.48%), Postives = 122/217 (56.22%), Query Frame = 3
Query: 1251 DEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSND-----VEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKP 1883
+++ + V+ + + +++ I FFRGLNIA GG A+ + ++GRR+ + L++F + RD+AL R KHHM GN R+I + +F+KIAG V ++L + +DQI++R++GLP+T T ++L FF D V +GI V+ G GDAFV+F E A A +G RY+E+F ST E+ QV++ + P P
Sbjct: 239 EKVCDNTVIRARGLPWQSSDQDIARFFRGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHM--GN-RYIEVYKATGEDFLKIAGGTTNEVAMFLSR---EDQIIVRMRGLPFTATYEQVLAFFSPKDGLNETCPVSGGKDGILFVRYPDGRPTGDAFVLFSCEEHALCALRKHKEILGKRYIELFKSTAAEVQQVLNRYSSTPLIP 449
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Medaka
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:101173047]) HSP 1 Score: 137.887 bits (346), Expect = 4.902e-33 Identity = 72/211 (34.12%), Postives = 119/211 (56.40%), Query Frame = 3
Query: 1248 NDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIM-SEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPF 1877
+ ++ + V+ + + +++ I FF+GLNIA GG+A+ + ++GRR+ + L++F D RD+AL R KHHM R+I + EF+KIAG + V +L + ++Q++IR++GLP+T T E+L+F + V G+ V+ G GDAFV+F E Q A +G RY+E+F ST E+ QV++ + P
Sbjct: 217 TEPVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFIDSEHRDLALERHKHHM---GCRYIEVYKATGEEFLKIAGGTSNEVAQFLSK---ENQVIIRMRGLPFTATSQEVLSFL-GPESPVTDGAEGLLFVKYPDGRPTGDAFVLFSCEEYVQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPL 420 HSP 2 Score: 50.8322 bits (120), Expect = 7.338e-6 Identity = 30/97 (30.93%), Postives = 53/97 (54.64%), Query Frame = 3
Query: 1575 TQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEG----VAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
T + +R++GLPYT +IL F + V+++ +G+ +V G +GDAF+ ++ VAQK T+ +RY+E+F + EM+ V+
Sbjct: 443 TSTRDCVRLRGLPYTAGIEDILEFMGEHTVDIK--PHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHK---KTMKDRYVEVFQCSTEEMSIVL 534
BLAST of Epithelial splicing regulatory protein 1/2 vs. Planmine SMEST
Match: SMESG000044612.1 (SMESG000044612.1) HSP 1 Score: 1221.45 bits (3159), Expect = 0.000e+0 Identity = 630/640 (98.44%), Postives = 631/640 (98.59%), Query Frame = 3
Query: 468 MTSGNLKRKXXXXXXXXXXKSDNLYLDSELNNDINKKLKMNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQNLDEISNFLQIEKPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKPKQNKQITKPTDSVNQENIKSSQKAVMSGTVTKYIPMEASDNDFVRYLADHRGLCLLSSRSHLYSPIGYISYVAFFKNSSDASATIKALRDKPFKVESSNKXXXXXXXXLPLVSKLEERPAMYSQVLHNMYPNSLPVNYVASLQNMLPNHSVQMPQPMNISNPLNFPFL 2387
MTSGNLKRKQQQQ + KSDNLYLDSELNNDINKKLKMNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVL SDDQTIEVIPVILGHLPLRSVLHRETRFRNINLNNYWYHYYNLFDEVSIFTSSKCQNLDEISNFLQIEKPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKPKQNKQITKPTDSVNQENIKSSQKAVMSGTVTKYIPMEASDNDFVRYLADHRGLCLLSSRSHLYSPIGYISYVAFFKNSSDASATIKALRDKPFKVESSNKEVTVETVELPLVSKLEERPAMYSQVLHNMYPNSLPVNYVASLQNMLP HSVQMPQPMNISNPLNFP
Sbjct: 1 MTSGNLKRKQQQQLDQYQ-KSDNLYLDSELNNDINKKLKMNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLFSDDQTIEVIPVILGHLPLRSVLHRETRFRNINLNNYWYHYYNLFDEVSIFTSSKCQNLDEISNFLQIEKPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKPKQNKQITKPTDSVNQENIKSSQKAVMSGTVTKYIPMEASDNDFVRYLADHRGLCLLSSRSHLYSPIGYISYVAFFKNSSDASATIKALRDKPFKVESSNKEVTVETVELPLVSKLEERPAMYSQVLHNMYPNSLPVNYVASLQNMLPYHSVQMPQPMNISNPLNFPIF 639
BLAST of Epithelial splicing regulatory protein 1/2 vs. Planmine SMEST
Match: SMESG000044612.1 (SMESG000044612.1) HSP 1 Score: 1196.8 bits (3095), Expect = 0.000e+0 Identity = 630/692 (91.04%), Postives = 631/692 (91.18%), Query Frame = 3
Query: 468 MTSGNLKRKXXXXXXXXXXKSDNLYLDSELNNDINKKLKMNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVSIFTSSKCQNLDEISNFLQIEKPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEI----------------------------------------------------LNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKPKQNKQITKPTDSVNQENIKSSQKAVMSGTVTKYIPMEASDNDFVRYLADHRGLCLLSSRSHLYSPIGYISYVAFFKNSSDASATIKALRDKPFKVESSNKXXXXXXXXLPLVSKLEERPAMYSQVLHNMYPNSLPVNYVASLQNMLPNHSVQMPQPMNISNPLNFPFL 2387
MTSGNLKRKQQQQ + KSDNLYLDSELNNDINKKLKMNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVL SDDQTIEVIPVILGHLPLRSVLHRETRFRNINLNNYWYHYYNLFDEVSIFTSSKCQNLDEISNFLQIEKPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEI LNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKPKQNKQITKPTDSVNQENIKSSQKAVMSGTVTKYIPMEASDNDFVRYLADHRGLCLLSSRSHLYSPIGYISYVAFFKNSSDASATIKALRDKPFKVESSNKEVTVETVELPLVSKLEERPAMYSQVLHNMYPNSLPVNYVASLQNMLP HSVQMPQPMNISNPLNFP
Sbjct: 1 MTSGNLKRKQQQQLDQYQ-KSDNLYLDSELNNDINKKLKMNPSKTILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQASSLLDPSANPDKIHISVPAREMTDLLSSPSSHSTFKLQDALNEIDSFINQNVLFSDDQTIEVIPVILGHLPLRSVLHRETRFRNINLNNYWYHYYNLFDEVSIFTSSKCQNLDEISNFLQIEKPGGTTMSIICYMSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSEGRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEIVSELNFLYFMSSLKVLLIFVYIIMCISAHPQIHRADPGLNYLWLDKRNEIIQLNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKPKQNKQITKPTDSVNQENIKSSQKAVMSGTVTKYIPMEASDNDFVRYLADHRGLCLLSSRSHLYSPIGYISYVAFFKNSSDASATIKALRDKPFKVESSNKEVTVETVELPLVSKLEERPAMYSQVLHNMYPNSLPVNYVASLQNMLPYHSVQMPQPMNISNPLNFPIF 691
BLAST of Epithelial splicing regulatory protein 1/2 vs. Planmine SMEST
Match: SMESG000023329.1 (SMESG000023329.1) HSP 1 Score: 204.912 bits (520), Expect = 9.635e-55 Identity = 143/434 (32.95%), Postives = 226/434 (52.07%), Query Frame = 3
Query: 603 ILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQAS----SLLDPSANPDKIHISVPARE--MTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVS----IFTSSKCQNLDEI---SNFLQIEKPGGTTMSIICY-MSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISA 1859
IL+ FH+VT G Q +DLG DET+I+ + + D +++I KL Q S S+ + N +++ E + D L + + +F L+D + S + + + V G P+R H E RN + +Y+N D + K LDE+ N I GG I C+ M I ++T G + + Y + +D + ++V+ + + ++ + I FFRGLNI GGIA+++S+ GRR+ + LI+F+ + RD+AL + KHHM R+I + + R+F+++AG + E +V+L++I Q LIR++GLPYT T +IL FF S + V+F +GI V G GDAFVIFENE VA++A IGNRY+E+F STP E+NQV+++
Sbjct: 4 ILVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSI--KLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLIS-----IGIPSISQCDFCLVTDGQAPMRLAFHPEIA-RNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIF-INDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHM---GQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNS 425
BLAST of Epithelial splicing regulatory protein 1/2 vs. Planmine SMEST
Match: SMESG000023329.1 (SMESG000023329.1) HSP 1 Score: 129.798 bits (325), Expect = 2.103e-32 Identity = 106/360 (29.44%), Postives = 178/360 (49.44%), Query Frame = 3
Query: 603 ILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQAS----SLLDPSANPDKIHISVPARE--MTDLLSSPSSHSTFKLQDALNEIDSFINQNVLVSDDQTIEVIPVILGHLPLRSVLHRETRFRXXXXXXXXXXXXXLFDEVS----IFTSSKCQNLDEI---SNFLQIEKPGGTTMSIICY-MSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEI 1637
IL+ FH+VT G Q +DLG DET+I+ + + D +++I KL Q S S+ + N +++ E + D L + + +F L+D + S + + + V G P+R H E RN + +Y+N D + K LDE+ N I GG I C+ M I ++T G + + Y + +D + ++V+ + + ++ + I FFRGLNI GGIA+++S+ GRR+ + LI+F+ + RD+AL + KHHM R+I + + R+F+++AG + E +V+L++I Q LIR++GLPYT T +I
Sbjct: 4 ILVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSI--KLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLIS-----IGIPSISQCDFCLVTDGQAPMRLAFHPEIA-RNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIF-INDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHM---GQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQI 351 HSP 2 Score: 53.1434 bits (126), Expect = 5.960e-7 Identity = 32/114 (28.07%), Postives = 58/114 (50.88%), Query Frame = 3
Query: 1581 DQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISAAQNIPFKPKQNKQITKPTDSV 1922
D++++R +GLP+ T +I FF+ ++E GI LV G NG+A + F++ A +G RY+E++ +T + QV A + ++ITKP+ ++
Sbjct: 229 DEVVVRARGLPWQATDSDINKFFRGLNIE----KGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV--AGGDTEEAEVFLQRITKPSQTL 336
BLAST of Epithelial splicing regulatory protein 1/2 vs. Planmine SMEST
Match: SMESG000055008.1 (SMESG000055008.1) HSP 1 Score: 55.8398 bits (133), Expect = 7.538e-8 Identity = 53/206 (25.73%), Postives = 97/206 (47.09%), Query Frame = 3
Query: 1275 LMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSEGRRSNKILIKF-EDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMK------IAGYENESVKVYLEQIETQ------DQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVI 1853
+ ++ + Y+T ++ II F + I G + +R+ + F E + + D+ +D+H+ G R+I + + +K +A EN + E+ +Q + ++R+KGLPY +K +I FF+ ++ +G+ ++ +G GDAFV F A+ AK G I +RY+E+F S E N I
Sbjct: 6 IKLRGMPYRTTMDDIIEFLPDIGIKGGKRGIHFPISQRNIEWGEAFIELESEEDLNKAKDRHNQHMGR-RYIEVFSSTKADMLKACKDMPVAVNENGRERPRRERSRSQVHERINENYVLRLKGLPYNASKTDIKEFFQG----LKILPDGMSILVDHNGRALGDAFVQFATYHDAKLAKERNGNKIAHRYIEVFDSNIEEANNEI 206 The following BLAST results are available for this feature:
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Epithelial splicing regulatory protein 1/2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Epithelial splicing regulatory protein 1/2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Epithelial splicing regulatory protein 1/2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002619 ID=SMED30002619|Name=Epithelial splicing regulatory protein 1/2|organism=Schmidtea mediterranea sexual|type=transcript|length=2884bpback to top protein sequence of SMED30002619-orf-1 >SMED30002619-orf-1 ID=SMED30002619-orf-1|Name=SMED30002619-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=798bp MTSGNLKRKQQQQQLEQYQKSDNLYLDSELNNDINKKLKMNPSKTILMAFback to top Annotated Terms
The following terms have been associated with this transcript:
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