Calmodulin

Overview
NameCalmodulin
Smed IDSMED30002597
Length (bp)785
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Calmodulin (SMED30002597) t-SNE clustered cells

Violin plots show distribution of expression levels for Calmodulin (SMED30002597) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Calmodulin (SMED30002597) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Calmodulin (SMED30002597) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30002597

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30002597h1SMcG0014561 dd_Smed_v4_3441_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30002597h1SMcG0014561 dd_Smed_v4_3441_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30002597h1SMcG0014561 dd_Smed_v4_3441_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30002597h1SMcG0014561 dd_Smed_v4_3441_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30002597h1SMcG0014561 dd_Smed_v4_3441_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30002597h1SMcG0014561 dd_Smed_v6_3441_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Calmodulin vs. Ensembl Human
Match: CALM1 (calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442])

HSP 1 Score: 93.5893 bits (231), Expect = 2.999e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    5 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 148          
BLAST of Calmodulin vs. Ensembl Human
Match: CALM2 (calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445])

HSP 1 Score: 93.5893 bits (231), Expect = 3.145e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Human
Match: CALM2 (calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445])

HSP 1 Score: 93.5893 bits (231), Expect = 3.145e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Human
Match: CALM1 (calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442])

HSP 1 Score: 93.5893 bits (231), Expect = 3.145e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Human
Match: CALM3 (calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449])

HSP 1 Score: 93.5893 bits (231), Expect = 3.145e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 99.3673 bits (246), Expect = 1.713e-25
Identity = 64/186 (34.41%), Postives = 101/186 (54.30%), Query Frame = 3
Query:   63 LTLFFSFSKERN*NSIQKQKMFRKS--TKLSKDKRKELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMTLQ 614
            +  FFS    R+  +I+ ++M   S   + S+D  K   L+ E+ +E R  F  FDKD +G I   EL  A++ LG+NPTE E+ EMI   D +  + ++EF EFC +MK     + T  E + + F++ DK+    I   E +  +   G+  +E+E+D   K  D D DG I + EF+K+M+ Q
Sbjct:    1 MVRFFSSRLARD-MAIRAERMAIPSNLMQFSEDIIK--QLTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVD-IDGNGQIEFPEFCVMMKRM--MKETDSEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMMSNQ 180          
BLAST of Calmodulin vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 98.2117 bits (243), Expect = 2.557e-25
Identity = 54/148 (36.49%), Postives = 83/148 (56.08%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMTLQ 614
             L+ E+ +E R  F  FDKD +G I   EL  A++ LG+NPTE E+ EMI   D +  + ++EF EFC +MK     + T  E + + F++ DK+    I   E +  +   G+  +E+E+D   K  D D DG I + EF+K+M+ Q
Sbjct:   17 QLTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVD-IDGNGQIEFPEFCVMMKRM--MKETDSEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMMSNQ 161          
BLAST of Calmodulin vs. Ensembl Celegans
Match: cmd-1 (Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O16305])

HSP 1 Score: 92.4337 bits (228), Expect = 3.709e-23
Identity = 52/146 (35.62%), Postives = 84/146 (57.53%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+ +MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Calmodulin vs. Ensembl Celegans
Match: cal-5 (CALmodulin related genes [Source:UniProtKB/TrEMBL;Acc:Q18136])

HSP 1 Score: 81.2629 bits (199), Expect = 7.050e-19
Identity = 48/154 (31.17%), Postives = 85/154 (55.19%), Query Frame = 3
Query:  147 SKDKRKELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
            S  K+ +  + + + ++L+  F+ FD +  GYI+  ELR  ++ +G++PTE+E+  M + AD  C D  ++F EF  + K            L  +F+ +D +    I R EL+ A    G +L++ +I A ++  D +NDG I+F EF ++MT
Sbjct:    6 SSKKKNQGEVGEIREDDLKGIFREFDLNGDGYIQREELRAVMQKMGQSPTEDELDAMFQAADKDC-DGNIDFQEFLVIAK-----ANPLSLSLKAVFEELDVDGDGYITRSELRTAFQRMGHSLSDQDIKAIYRHVDQNNDGKINFQEFCEMMT 153          
BLAST of Calmodulin vs. Ensembl Celegans
Match: tnc-2 (Troponin C, isoform 2 [Source:UniProtKB/Swiss-Prot;Acc:Q09665])

HSP 1 Score: 80.8777 bits (198), Expect = 9.742e-19
Identity = 51/149 (34.23%), Postives = 83/149 (55.70%), Query Frame = 3
Query:  174 LSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNF----ENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
            LS +Q E+ R+ F  FDK+  GYI A ++   L+ +G+   E ++K++IK  D      ++EF EF  ++ NF    EN +   EEEL + F++ DK     IN  +L+  L +   N++E+E+D      D D  G + F EFM++M+
Sbjct:   12 LSADQIEQFRKYFNMFDKEGKGYIRATQVGQILRTMGQAFEERDLKQLIKEFDADGS-GEIEFEEFAAMVANFVVNNENDEGL-EEELREAFRLYDKEGNGYINVSDLRDILRALDDNVSEEELDEMIAEIDADGSGTVDFDEFMEMMS 158          
BLAST of Calmodulin vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0304964)

HSP 1 Score: 92.4337 bits (228), Expect = 4.962e-23
Identity = 52/146 (35.62%), Postives = 84/146 (57.53%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+ +MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Calmodulin vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0088001)

HSP 1 Score: 92.4337 bits (228), Expect = 4.962e-23
Identity = 52/146 (35.62%), Postives = 84/146 (57.53%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+ +MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Calmodulin vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0304963)

HSP 1 Score: 92.4337 bits (228), Expect = 4.962e-23
Identity = 52/146 (35.62%), Postives = 84/146 (57.53%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+ +MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Calmodulin vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0088002)

HSP 1 Score: 92.4337 bits (228), Expect = 4.962e-23
Identity = 52/146 (35.62%), Postives = 84/146 (57.53%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+ +MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Calmodulin vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0345018)

HSP 1 Score: 92.4337 bits (228), Expect = 4.962e-23
Identity = 52/146 (35.62%), Postives = 84/146 (57.53%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+ +MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Calmodulin vs. Ensembl Zebrafish
Match: calm2a (calmodulin 2a (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030804-3])

HSP 1 Score: 93.5893 bits (231), Expect = 1.898e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Zebrafish
Match: calm3a (calmodulin 3a (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-5590])

HSP 1 Score: 93.5893 bits (231), Expect = 2.001e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Zebrafish
Match: calm3b (calmodulin 3b (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-527])

HSP 1 Score: 93.5893 bits (231), Expect = 2.001e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Zebrafish
Match: calm1b (calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2])

HSP 1 Score: 93.5893 bits (231), Expect = 2.001e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Zebrafish
Match: calm1b (calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2])

HSP 1 Score: 93.5893 bits (231), Expect = 2.001e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Xenopus
Match: CALM2 (calmodulin 1 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:100496298])

HSP 1 Score: 93.5893 bits (231), Expect = 2.851e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Xenopus
Match: CALM2 (calmodulin 1 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:100496298])

HSP 1 Score: 93.5893 bits (231), Expect = 2.851e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Xenopus
Match: calm2 (calmodulin 2 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:493522])

HSP 1 Score: 93.5893 bits (231), Expect = 2.851e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Xenopus
Match: calm2 (calmodulin 2 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:493522])

HSP 1 Score: 93.5893 bits (231), Expect = 2.851e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Xenopus
Match: tnnc2 (troponin C2, fast skeletal type [Source:NCBI gene;Acc:394554])

HSP 1 Score: 90.5077 bits (223), Expect = 6.231e-22
Identity = 59/160 (36.88%), Postives = 87/160 (54.37%), Query Frame = 3
Query:  132 KSTKLSKDKRKELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLM--KNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLM 605
            + T   +D R    LS+E   E +  F  FD D  G I   EL   ++MLG+NPT+ E+  +I+  D       ++F EF  +M  +  E+ Q   EEEL + F+I DKN    I+ +EL   L S G ++T++EI+   K  D +NDG I F EF+K+M
Sbjct:    3 QPTDQQQDARS--FLSEEMIAEFKAAFDMFDTDGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGS-GTIDFEEFLVMMVRQMKEDAQGKSEEELAECFRIFDKNADGYIDGEELAEILRSSGESITDEEIEELMKDGDKNNDGKIDFDEFLKMM 159          
BLAST of Calmodulin vs. Ensembl Mouse
Match: Calm3 (calmodulin 3 [Source:MGI Symbol;Acc:MGI:103249])

HSP 1 Score: 93.5893 bits (231), Expect = 2.159e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Mouse
Match: Calm1 (calmodulin 1 [Source:MGI Symbol;Acc:MGI:88251])

HSP 1 Score: 93.5893 bits (231), Expect = 2.159e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Mouse
Match: Calm2 (calmodulin 2 [Source:MGI Symbol;Acc:MGI:103250])

HSP 1 Score: 93.5893 bits (231), Expect = 2.159e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Mouse
Match: Calm1 (calmodulin 1 [Source:MGI Symbol;Acc:MGI:88251])

HSP 1 Score: 93.2041 bits (230), Expect = 1.029e-22
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:   52 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 195          
BLAST of Calmodulin vs. Ensembl Mouse
Match: Calml3 (calmodulin-like 3 [Source:MGI Symbol;Acc:MGI:1917655])

HSP 1 Score: 89.3521 bits (220), Expect = 7.920e-22
Identity = 49/146 (33.56%), Postives = 82/146 (56.16%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E++ M+   D    +  V+F EF  +M   +   T  EEE+ + F++ DK+    ++  EL+  +T  G  L+++E+D   + ADTD DG +++ EF+ ++ 
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGSITTQELGTVMRSLGQNPTEAELQGMVNEIDK-DGNGTVDFPEFLTMMSR-KMKDTDSEEEIREAFRVFDKDGNGFVSAAELRHVMTKLGEKLSDEEVDEMIQAADTDGDGQVNYEEFVHMLV 147          
BLAST of Calmodulin vs. UniProt/SwissProt
Match: sp|Q2R1Z5|CML6_ORYSJ (Putative calmodulin-like protein 6 OS=Oryza sativa subsp. japonica OX=39947 GN=CML6 PE=3 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 1.820e-24
Identity = 57/149 (38.26%), Postives = 87/149 (58.39%), Query Frame = 3
Query:  165 ELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKN--FENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLM 605
            E HL+++Q  + R  F  FDK+  G I   EL   L  LG  P++ ++++MI   D    +  +EF EF  +MK   +EN +   EEEL + F+I DK+    I+R+EL + + S G  +TEDEID   K AD++NDG + + EF ++M
Sbjct:    2 ESHLNEQQISDFRDAFSLFDKNNDGCISREELATVLTRLGMAPSQEDLQDMIVAVDE-DGNGTIEFDEFLAIMKKKLYENDKGDDEEELRKAFRIFDKDDNGFISRNELSMVMASLGEEMTEDEIDDMMKAADSNNDGQVDYEEFKRVM 149          
BLAST of Calmodulin vs. UniProt/SwissProt
Match: sp|P04630|CALL_CAEEL (Calmodulin-like protein OS=Caenorhabditis elegans OX=6239 GN=cal-1 PE=3 SV=1)

HSP 1 Score: 98.2117 bits (243), Expect = 3.253e-24
Identity = 54/148 (36.49%), Postives = 83/148 (56.08%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMTLQ 614
             L+ E+ +E R  F  FDKD +G I   EL  A++ LG+NPTE E+ EMI   D +  + ++EF EFC +MK     + T  E + + F++ DK+    I   E +  +   G+  +E+E+D   K  D D DG I + EF+K+M+ Q
Sbjct:   17 QLTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVD-IDGNGQIEFPEFCVMMKRM--MKETDSEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMMSNQ 161          
BLAST of Calmodulin vs. UniProt/SwissProt
Match: sp|P17928|CALM_MEDSA (Calmodulin OS=Medicago sativa OX=3879 GN=CAL1 PE=2 SV=2)

HSP 1 Score: 97.8265 bits (242), Expect = 4.240e-24
Identity = 56/145 (38.62%), Postives = 86/145 (59.31%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLM 605
             L+DEQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF +LM   +   T  EEEL + F++ DK++   I+  EL+  +T+ G  LT++E+D   + AD D DG I++ EF+K+M
Sbjct:    4 QLTDEQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLNLMAR-KMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVM 146          
BLAST of Calmodulin vs. UniProt/SwissProt
Match: sp|P13868|CALM1_SOLTU (Calmodulin-1 OS=Solanum tuberosum OX=4113 GN=PCM1 PE=1 SV=2)

HSP 1 Score: 97.8265 bits (242), Expect = 4.285e-24
Identity = 55/145 (37.93%), Postives = 88/145 (60.69%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLM 605
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI  AD   ++  ++F EF +LM   +   T  EEEL + FK+ DK++   I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMISEAD-ADQNGTIDFPEFLNLMAR-KMKDTDSEEELKEAFKVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVRMM 146          
BLAST of Calmodulin vs. UniProt/SwissProt
Match: sp|P07463|CALM_PARTE (Calmodulin OS=Paramecium tetraurelia OX=5888 GN=CAM PE=1 SV=3)

HSP 1 Score: 97.4413 bits (241), Expect = 4.865e-24
Identity = 55/146 (37.67%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  LM      Q + EEEL++ FK+ D++    I+  EL+  +T+ G  LT+DE+D   + AD D DG I++ EF+++M 
Sbjct:    4 QLTEEQIAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDA-DGNGTIDFPEFLSLMARKMKEQDS-EEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMMV 147          
BLAST of Calmodulin vs. TrEMBL
Match: A0A1I8HQ14 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig001318g1 PE=4 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 2.678e-33
Identity = 65/157 (41.40%), Postives = 101/157 (64.33%), Query Frame = 3
Query:  141 KLSKDKRKELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTRE--EELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLM 605
            K++++    L +SDE+ EEL+  F  FD+D+SG+IE  ELR+ L++LG+NPT+ E+  +I  AD +  D K++F EF  +MK+    ++  E   ELM  F++ D++    I+R EL+  LTS G  LT +E+D  F+ ADT+ DG IS+ EF+ L 
Sbjct:    2 KINQNLMDALKISDEELEELKEAFAIFDQDKSGFIEPQELRHILQVLGQNPTKAEIDSIIAEADVIVIDGKIDFNEFARIMKSNYKFKSASEMDNELMSAFQVFDRDSNGYISRQELEFVLTSIGERLTSEEVDEMFRFADTNEDGRISYKEFVVLF 158          
BLAST of Calmodulin vs. TrEMBL
Match: A0A1I8GRR9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 132.494 bits (332), Expect = 3.487e-31
Identity = 67/179 (37.43%), Postives = 109/179 (60.89%), Query Frame = 3
Query:   63 LTLFFSFSKERN*NSIQKQKM-FRKSTKLSKDKRKELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTRE--EELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPE 590
            L     F ++     + KQ + + ++ K++++    L +SDE+ EEL+  F  FD+D+SG+IE  ELR+ L++LG+NPT+ E+  +I  AD +  D K++F EF  +MK+    ++  E   ELM  F++ D++    I+R EL+  LTS G  LT +E+D  F+ ADT+ DG IS+ E
Sbjct: 2869 LEALICFRRQTAVTLVGKQSISWAETMKINQNLMDALKISDEELEELKEAFAIFDQDKSGFIEPQELRHILQVLGQNPTKAEIDSIIAEADVIVIDGKIDFNEFARIMKSNYKFKSASEMDNELMSAFQVFDRDSNGYISRQELEFVLTSIGERLTSEEVDEMFRFADTNEDGRISYKE 3047          
BLAST of Calmodulin vs. TrEMBL
Match: B4JT33 (GH23405 OS=Drosophila grimshawi OX=7222 GN=Dgri\GH23405 PE=3 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 2.837e-27
Identity = 63/147 (42.86%), Postives = 92/147 (62.59%), Query Frame = 3
Query:  168 LHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
            L +S+EQ  E R  F  FDK++SG I   EL N ++ LGENPTE E+++MI   DT   D +++F EFC LM   ++H+   EEEL + FKI DK++   I+  EL+  + + G  LT++EID   + AD D DG I + EF+ ++T
Sbjct:    5 LDISEEQIAEYREAFMLFDKNQSGRISTRELGNLMRSLGENPTEVELRDMINEVDT-SGDGEIDFQEFCQLMSR-QSHENDTEEELREAFKIFDKDEDGFISPAELRFVMINIGEKLTDEEIDDMIREADFDGDGKIDYEEFVYMIT 149          
BLAST of Calmodulin vs. TrEMBL
Match: A0A3M6TW34 (Uncharacterized protein OS=Pocillopora damicornis OX=46731 GN=pdam_00013116 PE=3 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 4.715e-24
Identity = 63/148 (42.57%), Postives = 90/148 (60.81%), Query Frame = 3
Query:  165 ELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
            E  L++EQ  ELR  F  FDKD SG I   EL   +K LG+NPTE+E++EMI+  D V  + +V+F EF  +MK     + T E E+ + F++ DKN    I+  EL+  +TS G  LTE+E+    K AD + DG I+F EF+ ++T
Sbjct:    3 ERQLTEEQINELREAFSLFDKDGSGTISNEELEVVMKSLGQNPTEDELQEMIREVD-VDGNGEVDFEEFLLMMKKQMQARDT-ESEIREAFRVFDKNGDGMISHSELRNVMTSLGEKLTEEEVSEMMKEADLNGDGYINFEEFVIMVT 148          
BLAST of Calmodulin vs. TrEMBL
Match: A0A1I8IYV5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 103.605 bits (257), Expect = 4.781e-24
Identity = 56/148 (37.84%), Postives = 86/148 (58.11%), Query Frame = 3
Query:  198 LRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTR-EEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMTLQLPAGKQKK 638
            +R  F  FD++ SGYIE+ ELRN L+ +G+NPT+ E+  +I+ AD            F  +MK++    +T  + EL+  F++ D++K   I+R EL+  L S G  LT +EID  F+ AD + DG IS+ EF+ L +    A  QK+
Sbjct:    1 MREAFDIFDQNSSGYIESFELRNVLQAMGQNPTQKEIDSIIQEAD------------FARIMKSYVFKNSTEIDNELLTAFQVFDRDKNGFISRQELEFVLKSIGEQLTTEEIDELFRSADANEDGKISYKEFVVLFSQPASAKGQKQ 136          
BLAST of Calmodulin vs. Ensembl Cavefish
Match: tnnc2 (troponin C type 2 (fast) [Source:ZFIN;Acc:ZDB-GENE-000322-2])

HSP 1 Score: 95.9005 bits (237), Expect = 4.233e-24
Identity = 55/147 (37.41%), Postives = 82/147 (55.78%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNF--ENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLM 605
            +LS+E   E +  F  FD D  G I  +EL   ++MLG+NPT  E+ E+I+  D       ++F EF  +M     E+     EEEL + F++ DKN    I+R+E    + S G ++TEDEID   K  D + DG++ F EF+K+M
Sbjct:   24 YLSEEMLAEFKAAFDMFDTDGGGDISTNELGTVMRMLGQNPTREELAEIIEEVDED-GSGSIDFEEFLVMMVRLLKEDQAGKSEEELAECFRVFDKNADGYIDREEFAEIIRSTGESITEDEIDELLKDGDKNADGMLDFDEFLKMM 169          
BLAST of Calmodulin vs. Ensembl Cavefish
Match: calm3a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 93.5893 bits (231), Expect = 1.696e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Cavefish
Match: calm2a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 93.5893 bits (231), Expect = 1.696e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Cavefish
Match: calm1b (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 93.5893 bits (231), Expect = 1.696e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Cavefish
Match: calm3a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 93.5893 bits (231), Expect = 1.696e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006008.1 (pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-1 gene:ENSPMAG00000005430.1 transcript:ENSPMAT00000006008.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 93.9745 bits (232), Expect = 2.815e-24
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITVKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Sea Lamprey
Match: CALML3 (calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:1452])

HSP 1 Score: 93.5893 bits (231), Expect = 3.263e-24
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Sea Lamprey
Match: CALM3 (calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449])

HSP 1 Score: 93.5893 bits (231), Expect = 3.440e-24
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Sea Lamprey
Match: si:rp71-17i16.4 (si:rp71-17i16.4 [Source:ZFIN;Acc:ZDB-GENE-090312-215])

HSP 1 Score: 86.2705 bits (212), Expect = 2.885e-21
Identity = 57/159 (35.85%), Postives = 86/159 (54.09%), Query Frame = 3
Query:  135 STKLSKDKRKELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLM--KNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLM 605
            +T+   D R   +L++EQ  E +  F  FD D  G I   EL   +K+LG+ PT+ E+  +I+  D       ++F EF  +M  +  E      EEEL + F+I+D N    I+RDELK  L + G N+T+ E+D   K  D + DG + F EF+K+M
Sbjct:    6 ATEAQHDARA--YLNEEQIAEFKAAFDMFDADGGGDISTSELGKVMKLLGQTPTKEELDAIIEEVDEDGS-GTIDFEEFLVMMVRQMKEESAGQTEEELAEAFRILDTNGDGYIDRDELKDILLNTGENVTDLEMDELMKDGDKNCDGRLDFDEFLKMM 161          
BLAST of Calmodulin vs. Ensembl Sea Lamprey
Match: CETN1 (centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866])

HSP 1 Score: 76.2554 bits (186), Expect = 2.421e-17
Identity = 54/164 (32.93%), Postives = 88/164 (53.66%), Query Frame = 3
Query:  126 FRKSTKLSKDKRKE----LHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLM 605
            FRK       +RK+      LS+EQ +E++  F  FD D SG I+  EL+ A++ LG  P + E+K+MI   D      K+ F +F  +M    + + +REE +++ F++ D ++T  I+   LK      G  LT++E+      AD D DG I+  EF+++M
Sbjct:   16 FRKLGGAGGAQRKKSGPKPELSEEQKQEIKEAFDLFDADGSGTIDVKELKVAMRALGFEPKKEEIKKMIADFDKDGS-GKINFNDFLAMMTQKMSEKDSREE-ILKAFRLFDDDETGKISFKNLKRVAKELGETLTDEELQEMIDEADRDGDGEINEEEFLRVM 177          
BLAST of Calmodulin vs. Ensembl Yeast
Match: CMD1 (Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability [Source:SGD;Acc:S000000313])

HSP 1 Score: 83.1889 bits (204), Expect = 1.979e-20
Identity = 52/146 (35.62%), Postives = 83/146 (56.85%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
            +L++EQ  E +  F  FDKD +G I + EL   ++ LG +P+E EV +++   D V  ++++EF EF  LM   +      E+EL++ FK+ DKN    I+  ELK  LTS G  LT+ E+D   +   +D  G I+  +F  L++
Sbjct:    4 NLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEID-VDGNHQIEFSEFLALMSR-QLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREV-SDGSGEINIQQFAALLS 146          
BLAST of Calmodulin vs. Ensembl Yeast
Match: MLC1 (Essential light chain for Myo1p; light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition [Source:SGD;Acc:S000003074])

HSP 1 Score: 56.225 bits (134), Expect = 1.544e-10
Identity = 37/134 (27.61%), Postives = 68/134 (50.75%), Query Frame = 3
Query:  210 FKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKD-NKVEFLEFCHLM----KNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFM 596
            F  FDK   G I    L + L+ +G NPT   V+++I  AD+  +D + +   +   L+    K  +     + E+ ++ F++ DK  T  ++  +L+  LT  G  LT+ E+D   K  + D++G I + +F+
Sbjct:   11 FTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIIN-ADSSLRDASSLTLDQITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFI 143          
BLAST of Calmodulin vs. Ensembl Yeast
Match: CDC31 (Calcium-binding component of the spindle pole body (SPB) half-bridge; required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; binds multiubiquitinated proteins and is involved in proteasomal protein degradation [Source:SGD;Acc:S000005783])

HSP 1 Score: 50.8322 bits (120), Expect = 1.520e-8
Identity = 43/153 (28.10%), Postives = 74/153 (48.37%), Query Frame = 3
Query:  174 LSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTRE--------EELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
            L +EQ +E+   F  FD +  G+++ HEL+ A+K LG    + E+ ++I   D+          E  HLMK  + +    E        +E+ + F++ D + T  I+   L+      G  LT++E+ A  +  D D DG I+  EF+ + T
Sbjct:   17 LLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDS----------EGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAICT 159          
BLAST of Calmodulin vs. Ensembl Yeast
Match: CNB1 (Calcineurin B; regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (stress-response transcription factor); other calcineurin subunit encoded by CNA1 and/or CMP1; regulates function of Aly1p alpha-arrestin; myristoylation by Nmt1p reduces calcineurin activity in response to submaximal Ca signals, is needed to prevent constitutive phosphatase activity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001673])

HSP 1 Score: 51.2174 bits (121), Expect = 1.523e-8
Identity = 42/142 (29.58%), Postives = 72/142 (50.70%), Query Frame = 3
Query:  183 EQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLAL-TSDGVNLTEDE----IDATFKCADTDNDGLISFPEF 593
            ++ E LR+ F   D+D SG I+ +E   ++  +  NP    + E+    ++      V+F EF   +  F + + +++E+L   FKI D +K   I+  EL + L    G NL +++    +D T    D+D DG +SF EF
Sbjct:   21 DEIERLRKRFMKLDRDSSGSIDKNEFM-SIPGVSSNPLAGRIMEVFDADNS----GDVDFQEFITGLSIF-SGRGSKDEKLRFAFKIYDIDKDGFISNGELFIVLKIMVGSNLDDEQLQQIVDRTIVENDSDGDGRLSFEEF 156          
BLAST of Calmodulin vs. Ensembl Nematostella
Match: EDO33580 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRU7])

HSP 1 Score: 97.0561 bits (240), Expect = 2.829e-25
Identity = 58/152 (38.16%), Postives = 85/152 (55.92%), Query Frame = 3
Query:  174 LSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMTLQLPAGK 629
            L++E+  E +  F  FDKD  G +   EL   ++ LG+NPT+ E++EMIK  D       + F EF  LM   +    + E+ELM  F+I DK+   +I   ELK  L S G  L+EDE+    K AD+D DG ++  EF+K+M + +  GK
Sbjct:    5 LTEEEIAEYKEAFSLFDKDGDGTVTTAELGTVMRNLGQNPTDEEIREMIKEVDEDGS-GSIGFEEFLQLMSK-KTKGKSYEDELMAAFQIFDKDGNGSITVTELKEVLDSLGEKLSEDEVGEMIKEADSDGDGTVNIEEFIKMM-VAITGGK 153          
BLAST of Calmodulin vs. Ensembl Nematostella
Match: EDO30674 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T043])

HSP 1 Score: 95.5153 bits (236), Expect = 2.003e-24
Identity = 54/147 (36.73%), Postives = 88/147 (59.86%), Query Frame = 3
Query:  165 ELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLM 605
            +  L+ EQ  EL+  F  FDKD SG I   EL   +K LG+NP++ E+++MI+  D    + +V+F EF  +MK    H+   E E+ + F++ D+N   +I+  EL+  + S G  L++DEI    + AD D DG+I+F EF++++
Sbjct:   10 DFELTAEQRNELQEAFSLFDKDGSGTISNEELEVVMKSLGQNPSDEELQQMIQEVDA-DGNGEVDFEEFLAMMKKQMQHRDA-EAEMREAFRVFDRNGDGSISEWELRSVMASLGEKLSDDEIKEMMREADLDGDGVINFQEFVQMV 154          

HSP 2 Score: 46.2098 bits (108), Expect = 2.584e-6
Identity = 21/66 (31.82%), Postives = 40/66 (60.61%), Query Frame = 3
Query:  420 ELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMTLQL 617
            EL + F + DK+ + TI+ +EL++ + S G N +++E+    +  D D +G + F EF+ +M  Q+
Sbjct:   20 ELQEAFSLFDKDGSGTISNEELEVVMKSLGQNPSDEELQQMIQEVDADGNGEVDFEEFLAMMKKQM 85          
BLAST of Calmodulin vs. Ensembl Nematostella
Match: EDO46518 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPI8])

HSP 1 Score: 94.3597 bits (233), Expect = 3.321e-24
Identity = 53/146 (36.30%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+K+MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMMT 147          
BLAST of Calmodulin vs. Ensembl Nematostella
Match: EDO30675 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T044])

HSP 1 Score: 93.2041 bits (230), Expect = 6.170e-24
Identity = 51/130 (39.23%), Postives = 78/130 (60.00%), Query Frame = 3
Query:  195 ELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISF 584
            EL+  F  FDKD  G I + EL + ++ LG+NPTE E+K+MI   D    + +++F EF  ++   +  +T  EEE+   FK+ DKN    I+  ELKL +++ G  LT+DE+D   + AD D DG+I +
Sbjct:    3 ELKEAFALFDKDGGGSISSSELAHVMRSLGQNPTEQELKDMIAEVDQ-DDNGEIDFPEFLQMVAK-KIKETDTEEEIQDAFKVFDKNGDGMISSSELKLVMSNLGERLTDDEVDEMIREADIDGDGMIDY 130          
BLAST of Calmodulin vs. Ensembl Nematostella
Match: EDO46606 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPN8])

HSP 1 Score: 88.1965 bits (217), Expect = 5.149e-22
Identity = 50/138 (36.23%), Postives = 80/138 (57.97%), Query Frame = 3
Query:  195 ELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
            E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+K+MT
Sbjct:    3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKNTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYDEFVKMMT 138          

HSP 2 Score: 58.151 bits (139), Expect = 8.447e-11
Identity = 30/64 (46.88%), Postives = 42/64 (65.62%), Query Frame = 3
Query:  192 EELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLM 383
            EE+R  F+ FDKD +G+I A ELR+ +  LGE  T+ EV EMI+ AD +  D +V + EF  +M
Sbjct:   75 EEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREAD-IDGDGQVNYDEFVKMM 137          
BLAST of Calmodulin vs. Ensembl Medaka
Match: tnnc2 (troponin C, skeletal muscle [Source:NCBI gene;Acc:101171829])

HSP 1 Score: 97.4413 bits (241), Expect = 9.061e-25
Identity = 55/147 (37.41%), Postives = 81/147 (55.10%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNF--ENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLM 605
            +LS+E   E +  F  FD D  G I   EL   ++MLG+NPT  E+ E+I+  D       ++F EF  +M     E+     EEEL + F++ DKN    I+R+E    + S G  ++EDEID   K  D +NDG++ F EF+K+M
Sbjct:   11 YLSEEMLAEFKAAFDMFDTDGGGDISTKELGTVMRMLGQNPTREELDEIIEEVDEDGS-GTIDFEEFLVMMVRLLKEDQAGKSEEELAECFRVFDKNGDGVIDREEFAQIIRSSGEPISEDEIDELMKDGDKNNDGMLDFDEFLKMM 156          
BLAST of Calmodulin vs. Ensembl Medaka
Match: calm2a (calmodulin 2 [Source:NCBI gene;Acc:100049420])

HSP 1 Score: 93.5893 bits (231), Expect = 1.685e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Medaka
Match: ENSORLT00000008599.2 (calmodulin 3 [Source:NCBI gene;Acc:100049421])

HSP 1 Score: 93.5893 bits (231), Expect = 1.685e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Medaka
Match: calm1b (calmodulin [Source:NCBI gene;Acc:100049419])

HSP 1 Score: 93.5893 bits (231), Expect = 1.685e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Calmodulin vs. Ensembl Medaka
Match: ENSORLT00000022188.2 (calmodulin [Source:NCBI gene;Acc:100049422])

HSP 1 Score: 93.2041 bits (230), Expect = 3.843e-23
Identity = 52/146 (35.62%), Postives = 85/146 (58.22%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+++MT
Sbjct:   18 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 161          
BLAST of Calmodulin vs. Planmine SMEST
Match: SMESG000008981.1 (SMESG000008981.1)

HSP 1 Score: 349.747 bits (896), Expect = 8.118e-124
Identity = 172/172 (100.00%), Postives = 172/172 (100.00%), Query Frame = 3
Query:  123 MFRKSTKLSKDKRKELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMTLQLPAGKQKK 638
            MFRKSTKLSKDKRKELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMTLQLPAGKQKK
Sbjct:    1 MFRKSTKLSKDKRKELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMTLQLPAGKQKK 172          
BLAST of Calmodulin vs. Planmine SMEST
Match: SMESG000040933.1 (SMESG000040933.1)

HSP 1 Score: 114.39 bits (285), Expect = 2.337e-31
Identity = 58/156 (37.18%), Postives = 100/156 (64.10%), Query Frame = 3
Query:  135 STKLSKDKRKELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKL 602
            S K  ++K+ E +L++++Y   +  F+ FD DR+GYI+  EL      +GE+P+++++  MI  ADT+ +D ++EF EF + M+N      +R E++   F++ D++   +I+R+EL++A+ + G  LTE E+D+    AD D DGLISF EF K+
Sbjct:   10 SKKNMENKKLEYNLTEKEYTAYKEAFELFDNDRNGYIDKQELLKMCHSIGEHPSDSQLDLMIAKADTLNRDGQIEFQEFVNFMRNNAVKHRSRTEDMKAAFRVFDRDGNGSIDREELRIAMENLGETLTEAELDSMIHEADCDGDGLISFDEFSKM 165          
BLAST of Calmodulin vs. Planmine SMEST
Match: SMESG000040933.1 (SMESG000040933.1)

HSP 1 Score: 113.62 bits (283), Expect = 3.126e-31
Identity = 56/151 (37.09%), Postives = 98/151 (64.90%), Query Frame = 3
Query:  150 KDKRKELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKL 602
            ++K+ E +L++++Y   +  F+ FD DR+GYI+  EL      +GE+P+++++  MI  ADT+ +D ++EF EF + M+N      +R E++   F++ D++   +I+R+EL++A+ + G  LTE E+D+    AD D DGLISF EF K+
Sbjct:    2 ENKKLEYNLTEKEYTAYKEAFELFDNDRNGYIDKQELLKMCHSIGEHPSDSQLDLMIAKADTLNRDGQIEFQEFVNFMRNNAVKHRSRTEDMKAAFRVFDRDGNGSIDREELRIAMENLGETLTEAELDSMIHEADCDGDGLISFDEFSKM 152          
BLAST of Calmodulin vs. Planmine SMEST
Match: SMESG000078272.1 (SMESG000078272.1)

HSP 1 Score: 93.9745 bits (232), Expect = 1.200e-23
Identity = 55/155 (35.48%), Postives = 85/155 (54.84%), Query Frame = 3
Query:  174 LSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMTLQLPAGKQKK 638
            ++ EQ  E++  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D +  + +++F EFC LM N     +  E +L  +FK+ D+N    + R+ELK+ + + G  LT+ EI+      D + DG+I F EF  LM       K +K
Sbjct:   13 MTPEQIAEMQEIFSLFDKDGGGTITTQELGAVMRALGQNPTEAELQDMISEID-IDGNGQIDFEEFCILM-NRRIKDSDLETDLKDVFKVFDRNGDGKVTRNELKIVMCNIGEVLTDSEIEEIMNLVDINGDGIIDFEEFNNLMINNASVDKMEK 165          
BLAST of Calmodulin vs. Planmine SMEST
Match: SMESG000034095.1 (SMESG000034095.1)

HSP 1 Score: 92.4337 bits (228), Expect = 3.889e-23
Identity = 52/146 (35.62%), Postives = 84/146 (57.53%), Query Frame = 3
Query:  171 HLSDEQYEELRRTFKSFDKDRSGYIEAHELRNALKMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEELMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDGLISFPEFMKLMT 608
             L++EQ  E +  F  FDKD  G I   EL   ++ LG+NPTE E+++MI   D    +  ++F EF  +M   +   T  EEE+ + F++ DK+    I+  EL+  +T+ G  LT++E+D   + AD D DG +++ EF+ +MT
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR-KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
The following BLAST results are available for this feature:
BLAST of Calmodulin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CALM12.999e-2335.62calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442][more]
CALM23.145e-2335.62calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445][more]
CALM23.145e-2335.62calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445][more]
CALM13.145e-2335.62calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442][more]
CALM33.145e-2335.62calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449][more]
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BLAST of Calmodulin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cal-11.713e-2534.41Calmodulin-like protein [Source:UniProtKB/Swiss-P... [more]
cal-12.557e-2536.49Calmodulin-like protein [Source:UniProtKB/Swiss-P... [more]
cmd-13.709e-2335.62Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O1630... [more]
cal-57.050e-1931.17CALmodulin related genes [Source:UniProtKB/TrEMBL... [more]
tnc-29.742e-1934.23Troponin C, isoform 2 [Source:UniProtKB/Swiss-Pro... [more]
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BLAST of Calmodulin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cam4.962e-2335.62gene:FBgn0000253 transcript:FBtr0304964[more]
Cam4.962e-2335.62gene:FBgn0000253 transcript:FBtr0088001[more]
Cam4.962e-2335.62gene:FBgn0000253 transcript:FBtr0304963[more]
Cam4.962e-2335.62gene:FBgn0000253 transcript:FBtr0088002[more]
Cam4.962e-2335.62gene:FBgn0000253 transcript:FBtr0345018[more]
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BLAST of Calmodulin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
calm2a1.898e-2335.62calmodulin 2a (phosphorylase kinase, delta) [Sourc... [more]
calm3a2.001e-2335.62calmodulin 3a (phosphorylase kinase, delta) [Sourc... [more]
calm3b2.001e-2335.62calmodulin 3b (phosphorylase kinase, delta) [Sourc... [more]
calm1b2.001e-2335.62calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2][more]
calm1b2.001e-2335.62calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2][more]
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BLAST of Calmodulin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CALM22.851e-2335.62calmodulin 1 (phosphorylase kinase, delta) [Source... [more]
CALM22.851e-2335.62calmodulin 1 (phosphorylase kinase, delta) [Source... [more]
calm22.851e-2335.62calmodulin 2 (phosphorylase kinase, delta) [Source... [more]
calm22.851e-2335.62calmodulin 2 (phosphorylase kinase, delta) [Source... [more]
tnnc26.231e-2236.88troponin C2, fast skeletal type [Source:NCBI gene;... [more]
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BLAST of Calmodulin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Calm32.159e-2335.62calmodulin 3 [Source:MGI Symbol;Acc:MGI:103249][more]
Calm12.159e-2335.62calmodulin 1 [Source:MGI Symbol;Acc:MGI:88251][more]
Calm22.159e-2335.62calmodulin 2 [Source:MGI Symbol;Acc:MGI:103250][more]
Calm11.029e-2235.62calmodulin 1 [Source:MGI Symbol;Acc:MGI:88251][more]
Calml37.920e-2233.56calmodulin-like 3 [Source:MGI Symbol;Acc:MGI:19176... [more]
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BLAST of Calmodulin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q2R1Z5|CML6_ORYSJ1.820e-2438.26Putative calmodulin-like protein 6 OS=Oryza sativa... [more]
sp|P04630|CALL_CAEEL3.253e-2436.49Calmodulin-like protein OS=Caenorhabditis elegans ... [more]
sp|P17928|CALM_MEDSA4.240e-2438.62Calmodulin OS=Medicago sativa OX=3879 GN=CAL1 PE=2... [more]
sp|P13868|CALM1_SOLTU4.285e-2437.93Calmodulin-1 OS=Solanum tuberosum OX=4113 GN=PCM1 ... [more]
sp|P07463|CALM_PARTE4.865e-2437.67Calmodulin OS=Paramecium tetraurelia OX=5888 GN=CA... [more]
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BLAST of Calmodulin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8HQ142.678e-3341.40Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8GRR93.487e-3137.43Uncharacterized protein OS=Macrostomum lignano OX=... [more]
B4JT332.837e-2742.86GH23405 OS=Drosophila grimshawi OX=7222 GN=Dgri\GH... [more]
A0A3M6TW344.715e-2442.57Uncharacterized protein OS=Pocillopora damicornis ... [more]
A0A1I8IYV54.781e-2437.84Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Calmodulin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tnnc24.233e-2437.41troponin C type 2 (fast) [Source:ZFIN;Acc:ZDB-GENE... [more]
calm3a1.696e-2335.62calmodulin [Source:NCBI gene;Acc:103037741][more]
calm2a1.696e-2335.62calmodulin [Source:NCBI gene;Acc:103037741][more]
calm1b1.696e-2335.62calmodulin [Source:NCBI gene;Acc:103037741][more]
calm3a1.696e-2335.62calmodulin [Source:NCBI gene;Acc:103037741][more]
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BLAST of Calmodulin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000006008.12.815e-2435.62pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-... [more]
CALML33.263e-2435.62calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:145... [more]
CALM33.440e-2435.62calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449][more]
si:rp71-17i16.42.885e-2135.85si:rp71-17i16.4 [Source:ZFIN;Acc:ZDB-GENE-090312-2... [more]
CETN12.421e-1732.93centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866][more]
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BLAST of Calmodulin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4
Match NameE-valueIdentityDescription
CMD11.979e-2035.62Calmodulin; Ca2+ binding protein that regulates Ca... [more]
MLC11.544e-1027.61Essential light chain for Myo1p; light chain for M... [more]
CDC311.520e-828.10Calcium-binding component of the spindle pole body... [more]
CNB11.523e-829.58Calcineurin B; regulatory subunit of calcineurin, ... [more]
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BLAST of Calmodulin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO335802.829e-2538.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO306742.003e-2436.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO465183.321e-2436.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO306756.170e-2439.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO466065.149e-2236.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Calmodulin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tnnc29.061e-2537.41troponin C, skeletal muscle [Source:NCBI gene;Acc:... [more]
calm2a1.685e-2335.62calmodulin 2 [Source:NCBI gene;Acc:100049420][more]
ENSORLT00000008599.21.685e-2335.62calmodulin 3 [Source:NCBI gene;Acc:100049421][more]
calm1b1.685e-2335.62calmodulin [Source:NCBI gene;Acc:100049419][more]
ENSORLT00000022188.23.843e-2335.62calmodulin [Source:NCBI gene;Acc:100049422][more]
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BLAST of Calmodulin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000008981.18.118e-124100.00SMESG000008981.1[more]
SMESG000040933.12.337e-3137.18SMESG000040933.1[more]
SMESG000040933.13.126e-3137.09SMESG000040933.1[more]
SMESG000078272.11.200e-2335.48SMESG000078272.1[more]
SMESG000034095.13.889e-2335.62SMESG000034095.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002597 ID=SMED30002597|Name=Calmodulin|organism=Schmidtea mediterranea sexual|type=transcript|length=785bp
CTTTATGAACTATAAATTCAGATTTACTCTTCGAATTTCATAATTGAAAA
CGAAATCCAATATTGACATTATTTTTTTCTTTCTCCAAGGAGCGAAATTG
AAATTCGATTCAGAAACAAAAAATGTTTAGAAAATCAACTAAACTGAGCA
AAGATAAACGAAAAGAATTACACTTATCAGACGAGCAATATGAAGAACTC
CGAAGAACTTTCAAATCGTTTGACAAAGACCGAAGCGGATATATTGAAGC
TCATGAATTACGGAATGCTTTGAAAATGTTAGGAGAGAATCCAACAGAAA
ATGAAGTGAAGGAAATGATTAAAGGAGCAGATACTGTTTGCAAAGACAAT
AAAGTTGAATTTCTGGAATTTTGTCATTTGATGAAAAACTTTGAAAACCA
CCAAACAACAAGGGAAGAAGAACTGATGCAATTATTTAAGATCATTGATA
AAAACAAAACGGATACCATTAATCGAGATGAACTAAAATTGGCTTTAACA
TCTGATGGGGTAAATCTGACTGAGGATGAAATTGATGCCACTTTCAAGTG
CGCTGATACAGATAATGATGGGTTGATATCCTTTCCAGAATTCATGAAAT
TAATGACTCTTCAACTTCCAGCAGGAAAGCAAAAGAAATAATTTTTTGTG
GACAAATTTGCTGTCATATTGTGAACAATTTTACGACAATTTCAACAAAA
ATTGTGAAAATTCCTTTTTAAATTATTGGTTTATATGTAGATCTTTTTTT
TCATTCGAGAAATATACATTCGTTTAGAAAAAAAA
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protein sequence of SMED30002597-orf-1

>SMED30002597-orf-1 ID=SMED30002597-orf-1|Name=SMED30002597-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=173bp
MFRKSTKLSKDKRKELHLSDEQYEELRRTFKSFDKDRSGYIEAHELRNAL
KMLGENPTENEVKEMIKGADTVCKDNKVEFLEFCHLMKNFENHQTTREEE
LMQLFKIIDKNKTDTINRDELKLALTSDGVNLTEDEIDATFKCADTDNDG
LISFPEFMKLMTLQLPAGKQKK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0019722calcium-mediated signaling
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR002048EF_hand_dom
IPR011992EF-hand-dom_pair
IPR018247EF_Hand_1_Ca_BS
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding
GO:0046872metal ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002048EF-hand domainSMARTSM00054efh_1coord: 25..53
e-value: 3.9E-6
score: 36.4
coord: 61..90
e-value: 2.4
score: 14.7
coord: 136..164
e-value: 5.7E-6
score: 35.8
coord: 100..128
e-value: 0.0058
score: 25.8
IPR002048EF-hand domainPFAMPF13499EF-hand_7coord: 98..161
e-value: 1.2E-16
score: 60.9
coord: 24..88
e-value: 9.4E-11
score: 42.0
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 132..167
score: 13.565
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 57..93
score: 6.675
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 96..131
score: 12.951
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 21..56
score: 15.741
IPR002048EF-hand domainCDDcd00051EFhcoord: 25..88
e-value: 2.27535E-15
score: 64.8765
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 92..169
e-value: 2.5E-20
score: 74.3
coord: 2..91
e-value: 9.7E-25
score: 88.6
NoneNo IPR availablePANTHERPTHR23050:SF345CALMODULIN-LIKE PROTEIN 6coord: 18..88
coord: 75..162
NoneNo IPR availablePANTHERPTHR23050CALCIUM BINDING PROTEINcoord: 18..88
coord: 75..162
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 109..121
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 145..157
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 34..46
IPR011992EF-hand domain pairSUPERFAMILYSSF47473EF-handcoord: 16..162