Oxysterol-binding protein

Query:  185 AEDENGQHGD---NHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            +E+++   GD   N I  +RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRLTEY+E++ L+ +A + +DP++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLELL  NE YTW N  C VHN+I+GK+WIE  G + IINH       L F   G FGK +H+V+G   Y Q KS+     +YGKWTE L+SV P  ++      K++       E       + ++  D +P  ++     +    L+W+  PRP NSA  YNFTSF M LN++       +P TD R R D+R ME G +D+A+  K  LEEKQRA R               S S E    R       WF +  NPY    +W ++G YW+R++   PDI+
Sbjct:    2 SEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEG---YIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTE-----EKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAAR------------KNRSKSEEDWKTR-------WFHQGPNPYNGAQDWIYSGSYWDRNYFNLPDIY 437          

Query:  185 AEDENGQHGD---NHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            +E+++   GD   N I  +RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRLTEY+E++ L+ +A + +DP++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLELL  NE YTW N  C VHN+I+GK+WIE  G + IINH       L F   G FGK +H+V+G   Y Q KS+     +YGKWTE L+SV P  ++      K++       E       + ++  D +P  ++     +    L+W+  PRP NSA  YNFTSF M LN++       +P TD R R D+R ME G +D+A+  K  LEEKQRA R               S S E    R       WF +  NPY    +W ++G YW+R++   PDI+
Sbjct:  133 SEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEG---YIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTE-----EKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAAR------------KNRSKSEEDWKTR-------WFHQGPNPYNGAQDWIYSGSYWDRNYFNLPDIY 568          

Query:  212 DNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPT--FKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKR--HVNST--DQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEG---PVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            +N I  +RT LP PM S+ +FSVWT LK+C+G ELSKITMPI FNEP+SFLQR+TEY+E+  L+ +A  +  P++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+++SEQ+ HHPP+SAFH E     F F+G+I+PKL FWGKSV   P+G ITLELL  NE YTW N  C VHNVIIGK+WIE  G + I+NH       L F   G FGK +H+V+G I   Q K++     +YGKWTE L+ + P  +       +R  H+     D+       D  ++           P        +L+W+   RP NSA  YNFTSFT+ LN++     + LPPTD R R D+R ME G +D A+  K  LEEKQR  R                        R ++E      WF    NPYT   +W + G+Y+ R++S CPDI+
Sbjct:   22 ENGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHI---QDKNKKKLFMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIP------GSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRE----------------------RAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY 448          

Query:  212 DNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPT--FKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKR--HVNST--DQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEG---PVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            +N I  +RT LP PM S+ +FSVWT LK+C+G ELSKITMPI FNEP+SFLQR+TEY+E+  L+ +A  +  P++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+++SEQ+ HHPP+SAFH E     F F+G+I+PKL FWGKSV   P+G ITLELL  NE YTW N  C VHNVIIGK+WIE  G + I+NH       L F   G FGK +H+V+G I   Q K++     +YGKWTE L+ + P  +       +R  H+     D+       D  ++           P        +L+W+   RP NSA  YNFTSFT+ LN++     + LPPTD R R D+R ME G +D A+  K  LEEKQR  R                        R ++E      WF    NPYT   +W + G+Y+ R++S CPDI+
Sbjct:   54 ENGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHI---QDKNKKKLFMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIP------GSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRE----------------------RAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY 480          

Query:  212 DNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPT--FKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKR--HVNST--DQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEG---PVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            +N I  +RT LP PM S+ +FSVWT LK+C+G ELSKITMPI FNEP+SFLQR+TEY+E+  L+ +A  +  P++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+++SEQ+ HHPP+SAFH E     F F+G+I+PKL FWGKSV   P+G ITLELL  NE YTW N  C VHNVIIGK+WIE  G + I+NH       L F   G FGK +H+V+G I   Q K++     +YGKWTE L+ + P  +       +R  H+     D+       D  ++           P        +L+W+   RP NSA  YNFTSFT+ LN++     + LPPTD R R D+R ME G +D A+  K  LEEKQR  R                        R ++E      WF    NPYT   +W + G+Y+ R++S CPDI+
Sbjct:   54 ENGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHI---QDKNKKKLFMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIP------GSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRE----------------------RAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY 480          

Query:  233 RTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPNFKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWF---GKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            RT LP    +  + S+W  ++  +GK+ S+ T+P+  NEP+SFLQRL+E ++Y+ LL++A   +D ++R+E + AFA++  ++N  R+ KPFNPLL ET+EL R   ++++EQ+ HHPP+SA + ES  F   G + P L FW   ++  P  ++ L      E Y+W    C ++NVI+GK+++  +  M+ I  S    A  +F + G++   G ++H V+G I+ G+ K     + +YG WT  L S   E +        R  N T                     +D  P    +   +++W +   P      ++FT+FT+ LN++    S  + PTDSR R+DM+ +E+G  DEA   K+  EE+QR +R                   +  D+      P+WFA+      ++  W + G YW+RD+S C ++F
Sbjct:   20 RTRLPATYIAPEDVSIWDIIRPNLGKDFSRFTVPVFMNEPLSFLQRLSENVQYNYLLEKAAKCSDDMERIEYVAAFALATVSANHKRLSKPFNPLLLETFELERNGVRFLAEQVSHHPPISAVYAESDEFTVEGTVEPTLGFWMTKLLANPHAHLKLTFKKTGETYSWSAPKCAIYNVIMGKMYMNFTSHMK-IESSGTYDAVFSFDNKGYYNHKGGDVH-VEGHIFEGKNKI----KALYGNWTLFLASCDNEDFKHHRKEYLRMFNET------------------VSEKDQGPV---VPGSKILWVSNQIPKLFDDQFHFTNFTLSLNEMYPGMSDTVAPTDSRRRKDMKALEDGKNDEAEEFKHKYEEEQRERRTT-----------------KTGDV------PMWFAK-----NDEGHWAYKGGYWDRDYSNCLELF 407          

Query:  233 RTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPNFKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWF---GKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            RT LP    +  + S+W  ++  +GK+ S+ T+P+  NEP+SFLQRL+E ++Y+ LL++A   +D ++R+E + AFA++  ++N  R+ KPFNPLL ET+EL R   ++++EQ+ HHPP+SA + ES  F   G + P L FW   ++  P  ++ L      E Y+W    C ++NVI+GK+++  +  M+ I  S    A  +F + G++   G ++H V+G I+ G+ K     + +YG WT  L S   E +        R  N T                     +D  P    +   +++W +   P      ++FT+FT+ LN++    S  + PTDSR R+DM+ +E+G  DEA   K+  EE+QR +R                   +  D+      P+WFA+      ++  W + G YW+RD+S C ++F
Sbjct:   30 RTRLPATYIAPEDVSIWDIIRPNLGKDFSRFTVPVFMNEPLSFLQRLSENVQYNYLLEKAAKCSDDMERIEYVAAFALATVSANHKRLSKPFNPLLLETFELERNGVRFLAEQVSHHPPISAVYAESDEFTVEGTVEPTLGFWMTKLLANPHAHLKLTFKKTGETYSWSAPKCAIYNVIMGKMYMNFTSHMK-IESSGTYDAVFSFDNKGYYNHKGGDVH-VEGHIFEGKNKI----KALYGNWTLFLASCDNEDFKHHRKEYLRMFNET------------------VSEKDQGPV---VPGSKILWVSNQIPKLFDDQFHFTNFTLSLNEMYPGMSDTVAPTDSRRRKDMKALEDGKNDEAEEFKHKYEEEQRERRTT-----------------KTGDV------PMWFAK-----NDEGHWAYKGGYWDRDYSNCLELF 417          

Query:  251 PMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN---FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHR-VDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYW----NRDWSVCPDIF 1552
            P    L  ++W+ +K CIGKELSKI MP+ F+EPIS LQR+TE +EY+ LL+   A+   +++M  + A+A S  ++   R  KPFNPLLGET+E  R +   ++ V+EQ+ HHPP +A H E   +  Y        F GK + + P G   +        ++++ +  TVHN+I+GK+WI++ G M I NH  N    L F    +F +   R V G +   +   ++V   V G W +++  +    WN +    K  V+ T                                + + IW A P P N+   +NFT   + LN+  +  +    PTDSR R D R ME G  DEA   K  +EEKQR  R   ++                   + ++  P WF    +     +  QF G YW     ++W  CPDIF
Sbjct:   57 PERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETG-AKLSTLEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYV---VQGTWDKSIDMLKVSSWNGNHEKPKLEVDET--------------------------------SLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVA----PTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKGD---------KYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNWEKCPDIF 449          

Query:  251 PMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN---FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHR-VDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYW----NRDWSVCPDIF 1552
            P    L  ++W+ +K CIGKELSKI MP+ F+EPIS LQR+TE +EY+ LL+   A+   +++M  + A+A S  ++   R  KPFNPLLGET+E  R +   ++ V+EQ+ HHPP +A H E   +  Y        F GK + + P G   +        ++++ +  TVHN+I+GK+WI++ G M I NH  N    L F    +F +   R V G +   +   ++V   V G W +++  +    WN +    K  V+ T                                + + IW A P P N+   +NFT   + LN+  +  +    PTDSR R D R ME G  DEA   K  +EEKQR  R   ++                   + ++  P WF    +     +  QF G YW     ++W  CPDIF
Sbjct:  235 PERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETG-AKLSTLEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYV---VQGTWDKSIDMLKVSSWNGNHEKPKLEVDET--------------------------------SLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVA----PTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKGD---------KYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNWEKCPDIF 627          

Query:  251 PMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN---FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHR-VDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYW----NRDWSVCPDIF 1552
            P    L  ++W+ +K CIGKELSKI MP+ F+EPIS LQR+TE +EY+ LL+   A+   +++M  + A+A S  ++   R  KPFNPLLGET+E  R +   ++ V+EQ+ HHPP +A H E   +  Y        F GK + + P G   +        ++++ +  TVHN+I+GK+WI++ G M I NH  N    L F    +F +   R V G +   +   ++V   V G W +++  +    WN +    K  V+ T                                + + IW A P P N+   +NFT   + LN+  +  +    PTDSR R D R ME G  DEA   K  +EEKQR  R   ++                   + ++  P WF    +     +  QF G YW     ++W  CPDIF
Sbjct:  340 PERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETG-AKLSTLEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYV---VQGTWDKSIDMLKVSSWNGNHEKPKLEVDET--------------------------------SLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVA----PTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKGD---------KYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNWEKCPDIF 732          

Query:  209 GDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPNFKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVW----------NDD-------------SSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFS--RELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            GD   +  RT LP  M S+   S+W  LK CIGK+LSKITMP++ NEP+SFLQRL EY+EY++LL +A  +  P  RM+ + AFAVS  ASNW R+GKPFNPLLGETYEL + +++ V EQ+ HHPPVSAFH ES  FKF+G I PK+ FWGKSV + PKG +T+E   WNE Y+W NV C VHN+I+G++WIE  G M I NH+   +A LTF S G   KN+HRV+G +      + +    +YGKWTE +   S E +          NDD             S  +   +NS   +   +       + +  +P+ ++   + + +   +W  KPRP N + +Y FT F + LN +  +      L PTDSR R D+ ++EEG LD A+  K  LEEKQR  R                   +     +    P WF    NP+T   +W ++G YW+R +     IF
Sbjct:    4 GDYAEHVERTELPATMISRKEVSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEHPADRMKYVAAFAVSALASNWERLGKPFNPLLGETYELQKGDYRIVCEQVSHHPPVSAFHAESKDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIVGRLWIEQYGKMEITNHATGHVASLTFKSAGSGAKNLHRVEGFVKDASETNLYF---LYGKWTEFIKCCSAESYVQFLKQGTRKNDDYDGSPNGTPKKMFSKLNSFKLNSFRSLSIQDSDSYPPMEQEGDIPKSDSAYSLDIPDSTTLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILHLEEGNLDGASKEKTRLEEKQRHTR------------------KQRKSTNSDDWSPRWFKYATNPHTKIDDWLYSGGYWDRKYDNTDTIF 455          

Query:  209 GDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPNFKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVW----------NDD-----SSTSKRHVNSTD----------QIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFS--RELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            GD   +  RT LP  M S+   S+W  LK CIGK+LSKITMP++ NEP+SFLQRL EY+EY++LL +A  +  P  RM+ + AFAVS  ASNW R+GKPFNPLLGETYEL + +++ V EQ+ HHPPVSAFH ES  FKF+G I PK+ FWGKSV + PKG +T+E   WNE Y+W NV C VHN+I+G++WIE  G M I NH+   +A LTF S G   KN+HRV+G +      + +    +YGKWTE +   S E +          NDD     + T K+  +  +           I++         + +  +P+ ++   + + +   +W  KPRP N + +Y FT F + LN +  +      L PTDSR R D+ ++EEG LD A+  K  LEEKQR  R                   +     +    P WF    NP+T   +W ++G YW+R +     IF
Sbjct:    4 GDYAEHVERTELPATMISRKEVSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEHPADRMKYVAAFAVSALASNWERLGKPFNPLLGETYELQKGDYRIVCEQVSHHPPVSAFHAESKDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIVGRLWIEQYGKMEITNHATGHVASLTFKSAGSGAKNLHRVEGFVKDASETNLYF---LYGKWTEFIKCCSAESYVQFLKQGTRKNDDYDGSPNGTPKKMFSKLNSFKLNSFRSLSIQDVSSDSYPPMEQEGDIPKSDSAYSLDIPDSTTLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILHLEEGNLDGASKEKTRLEEKQRHTR------------------KQRKSTNSDDWSPRWFKYATNPHTKIDDWLYSGGYWDRKYDNTDTIF 457          

Query:  254 MPSKLN--FSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN---FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRI----INHSNNCIADLTFHSVGWFGKNMHR-VDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAK 1324
            +P K N   S+W  +K CIGK+LSKI MPI FNEP+S LQRL E  EY+E+LD A    D  +++  I AF VS  A+   R GKPFNPLLGETYE  R +   ++ ++EQ+ HHPPV+A H ES  +  +        F GK V I P G + ++       Y+W+ V  TV+N+I+GK+W++  G M I        + CI  L F    +F +++ R V G +     K   V+  V G W +    ++P +    S +S  +                                      +L W+ +P P +S  FYNFT+    LN+  +  +    PTDSR R D R ME+G  DE+   K
Sbjct:  390 VPDKPNHPISLWGIMKNCIGKDLSKIPMPINFNEPLSMLQRLVEDYEYTEILDYAATCQDECEQLAYIAAFTVSAYATTTNRTGKPFNPLLGETYECDRMDDYGWRCLAEQVSHHPPVAALHCESKNWTCWQEFSMTSKFRGKYVQINPLGGVYVQFPNSGRRYSWRKVTTTVNNIIVGKLWVDQHGEMEIRGSQAAEGHKCI--LNFIPYSYFSRDVQRSVKGVV---MNKDNEVKWVVRGTW-DMKIEIAPVLKTSGSVSSPTYTTG---------------------------------EFKLAWRRRPAPPDSDKFYNFTTLACQLNEEEEGVA----PTDSRLRPDQRLMEQGDWDESNKEK 713          

Query:  278 VWTFLKQCI-GKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELH--RPNFK---YVSEQICHHPPVSAFHV--ESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFG 871
            +W  +KQ   G +LSK+ +P    EP SFL +L++   +++LL +AV E D   RM+ +  + +S        + KP+NP+LGE +  +   P+     Y++EQ+ HHPPVSAF+V      F    +I  K  F+G S     +G  T+ LLP  E YT          +++G + +E  G + I   +     +L F    + G
Sbjct:  106 IWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDSYYHADLLSKAVQEDDAFTRMKLVVQWYLSSFYKKPKGLKKPYNPILGERFRCYWQHPSGSRTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSKFYGNSTSAVLEGAATMTLLPRGECYTATTPYAHCKGILMGTLSMELGGKINIECENTGYRTELEFKLKPFLG 311          

Query:  278 VWTFLKQCI-GKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELH--RPNFK---YVSEQICHHPPVSAFHV--ESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFG 871
            +W  +KQ   G +LSK+ +P    EP SFL +L++   +++LL +AV E D   RM+ +  + +S        + KP+NP+LGE +  +   P+     Y++EQ+ HHPPVSAF+V      F    +I  K  F+G S     +G  T+ LLP  E YT          +++G + +E  G + I   +     +L F    + G
Sbjct:  438 IWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDSYYHADLLSKAVQEDDAFTRMKLVVQWYLSSFYKKPKGLKKPYNPILGERFRCYWQHPSGSRTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSKFYGNSTSAVLEGAATMTLLPRGECYTATTPYAHCKGILMGTLSMELGGKINIECENTGYRTELEFKLKPFLG 643          

Query:  176 YFDAEDENGQ-HGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVES--PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKE-GPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            Y  A+  NG    +N I   R+ LP PM S+ +FSVW+ LK+CIG ELSKITMPIVFNEP+SFLQRLTEY+E++ LL +A  ++D I+RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH ES    F F+G+I+PKL FWGKSV   PKG ITLEL    E YTW N  C VHNVI+GK+WIE  G + IINHS      L F   G FGK +HRV+G I    +K R V   +YGKWTE ++SV P+ +       K+    T + + +E    N +  + P  Q+       +    L+W+   RP  SA  YNFT+F M LN++       L PTD R R D+R ME G +DEA+  K  LEEKQRA R                        +N++E    WF    NPYT   +W +TG Y++R +  CPDI+
Sbjct:   34 YDGAQKNNGAVPQENGIKKRRSCLPAPMFSRNDFSVWSILKKCIGLELSKITMPIVFNEPLSFLQRLTEYMEHTYLLQKACLQSDSIERMQTVAAFAVSAVASQWDRTGKPFNPLLGETYELTREDQGFRLISEQVSHHPPISAFHTESLMGDFVFHGSIYPKLKFWGKSVEAEPKGTITLELHKHKEAYTWTNPFCCVHNVILGKLWIEQYGTVEIINHSTGEKCVLNFKPCGMFGKELHRVEGYIQDKSKKKRCV---IYGKWTECMWSVDPQAYEAHRKLEKKGTTDTKKQKQEEPEAVNEDADEMPEVQETVAV---IPGSTLLWRISSRPPLSAEMYNFTNFAMALNELEPGMEGVLAPTDCRLRPDIRAMENGNMDEASREKERLEEKQRAARKE--------------------RAKNEEEWSTRWFQLGTNPYTGSQDWLYTGGYFDRKYRNCPDIY 472          

Query:  176 YFDAEDENGQ-HGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVES--PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKE-GPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            Y  A+  NG    +N I   R+ LP PM S+ +FSVW+ LK+CIG ELSKITMPIVFNEP+SFLQRLTEY+E++ LL +A  + D I+RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH ES    F F+G+I+PKL FWGKSV   PKG ITLEL    E YTW N  C VHNVI+GK+WIE  G + IINHS      L F   G FGK +HRV+G I    +K R V   +YGKWTE ++SV P+ +       K+    T + + +E    N +  + P  Q+       +    L+W+   RP  SA  YNFT+F M LN++       L PTD R R D+R ME G +DEA+  K  LEEKQRA R                        +N++E    WF    NPYT   +W +TG Y++R +  CPDI+
Sbjct:   31 YDGAQKNNGAVPQENGIKKRRSCLPAPMFSRNDFSVWSILKKCIGLELSKITMPIVFNEPLSFLQRLTEYMEHTYLLQKACLQNDSIERMQTVAAFAVSAVASQWDRTGKPFNPLLGETYELTREDQGFRLISEQVSHHPPISAFHTESLMGDFVFHGSIYPKLKFWGKSVEAEPKGTITLELHKHKEAYTWTNPFCCVHNVILGKLWIEQYGTVEIINHSTGEKCVLNFKPCGMFGKELHRVEGYIQDKSKKKRCV---IYGKWTECMWSVDPQAYEAHRKLEKKGTTDTKKQKQEEPEAVNEDADEMPEVQETVAV---IPGSTLLWRISSRPPLSAEMYNFTNFAMALNELEPGMEGVLAPTDCRLRPDIRAMENGNMDEASREKERLEEKQRAARKE--------------------RAKNEEEWSTRWFQLGTNPYTGSQDWLYTGGYFDRKYRNCPDIY 469          

Query:  176 YFDAEDENGQ-HGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVES--PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            Y + +  NG+   +N ++  RT LP PM S+ +FSVW FLK+CIG ELSKITMPIVFNEP+SFLQR+TEY+E++ L+ +A   +D I+RM+ + AFAVS  AS W R GKPFNPLLGET+EL R +  ++ +SEQ+ HHPP+SAF+ ES    F F+G+I+PKL FWGKSV   PKG +TLEL    E YTW N +C VHNVI+GK+WIE  G + I+NHS      L F   G FGK +HRV+G I   Q KS+     +YGKWTE ++S+ P+V+  +    K+    + + + D+     + D    + +  T     +   +L+W+  PRP  S   YNFT+F M LN++    +  L PTD R R D+R ME G +D A+  K  LEEKQRA R             + +   E    R       WF +  NPYT   +W + G Y++R +S  PDI+
Sbjct:   38 YANKQTANGKVPSENGVWERRTTLPAPMFSRNDFSVWGFLKKCIGMELSKITMPIVFNEPLSFLQRITEYMEHTYLIHKACTLSDSIERMQFVAAFAVSAVASQWDRTGKPFNPLLGETFELTREDEGYRMISEQVSHHPPISAFYAESLNQDFSFHGSIYPKLKFWGKSVEAEPKGTMTLELSKHREAYTWTNPMCCVHNVILGKLWIEQYGTVEIVNHSTGDKCVLNFKPCGMFGKELHRVEGHI---QDKSKKKHWVMYGKWTECMYSIEPKVYEANKKAEKKSGGESKKHKQDQGTGGEDADEMPDVQETVT----MIPGSKLLWRVAPRPPQSTEMYNFTNFAMTLNELEPGMTEVLAPTDCRLRPDIRAMENGDIDSASREKERLEEKQRAAR------------RERAKDEEDWSTR-------WFQQGNNPYTGTADWIYKGGYFDRRYSELPDIY 475          

Query:  176 YFDAEDENGQ-HGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVES--PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            Y + +  NG+   +N ++  RT LP PM S+ +FSVW FLK+CIG ELSKITMPIVFNEP+SFLQR+TEY+E++ L+ +A   +D I+RM+ + AFAVS  AS W R GKPFNPLLGET+EL R +  ++ +SEQ+ HHPP+SAF+ ES    F F+G+I+PKL FWGKSV   PKG +TLEL    E YTW N +C VHNVI+GK+WIE  G + I+NHS      L F   G FGK +HRV+G I   Q KS+     +YGKWTE ++S+ P+V+  +    K+    + + + D+     + D    + +  T     +   +L+W+  PRP  S   YNFT+F M LN++    +  L PTD R R D+R ME G +D A+  K  LEEKQRA R             + +   E    R       WF +  NPYT   +W + G Y++R +S  PDI+
Sbjct:   30 YANKQTANGKVPSENGVWERRTTLPAPMFSRNDFSVWGFLKKCIGMELSKITMPIVFNEPLSFLQRITEYMEHTYLIHKACTLSDSIERMQFVAAFAVSAVASQWDRTGKPFNPLLGETFELTREDEGYRMISEQVSHHPPISAFYAESLNQDFSFHGSIYPKLKFWGKSVEAEPKGTMTLELSKHREAYTWTNPMCCVHNVILGKLWIEQYGTVEIVNHSTGDKCVLNFKPCGMFGKELHRVEGHI---QDKSKKKHWVMYGKWTECMYSIEPKVYEANKKAEKKSGGESKKHKQDQGTGGEDADEMPDVQETVT----MIPGSKLLWRVAPRPPQSTEMYNFTNFAMTLNELEPGMTEVLAPTDCRLRPDIRAMENGDIDSASREKERLEEKQRAAR------------RERAKDEEDWSTR-------WFQQGNNPYTGTADWIYKGGYFDRRYSELPDIY 467          

Query:  194 ENGQHGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVES--PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            +  Q   N +  +R+ LP  M S+ N S+W+ LK+CIG ELSKITMP++FNEP+SFLQRLTEY+E++ L+ +A A  D I RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+++SEQ+ HHPP+SAFH E     F F+G+I+PKL FWGKSV   P+G I+LEL   +E YTW N  C VHN+I+G++WIE  G + IINH       LTF S G FGK +H+V+G   Y   KS+     +YGKWTE L+SV P  +     +  +    +    +  + + +     +       P         LIW+  PRPDNS  +Y FT+F + LN++     + LPPTD R R D+R +E G +D A+  KN LEEKQR  R               S S+E   IR       WF +  NP+T   +W +   YW+R++S  PDI+
Sbjct:   24 QGDQTQRNGVKNHRSALPAAMFSRNNISMWSVLKKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHRANASQDSIHRMKCVAAFAVSAVASQWERTGKPFNPLLGETYELVREDLGFRWISEQVSHHPPISAFHAEGIKKDFMFHGSIYPKLKFWGKSVEAEPRGIISLELPGHSEAYTWTNPTCCVHNIIMGQLWIEQYGNVEIINHKTGERCCLTFKSCGIFGKELHKVEG---YILDKSKKKVCALYGKWTECLYSVDPAAFEAHRKSDVKRPEKSSTPSSHAEEEPDEMPPPEAETVQLIP------GSELIWRISPRPDNSGKYYAFTTFALQLNELDVEMEKVLPPTDCRLRPDIRALENGNIDIASAEKNRLEEKQRTAR------------KDRSKSNEEWKIR-------WFHQGSNPHTGAPDWLYNDNYWSRNYSQLPDIY 452          

Query:  233 RTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWN--------DDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRL+EY+E++ L+ +A   +D ++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPPVSAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLELL   E YTW N  C VHN+I+GK+WIE  G M I NH       L F     F K +H+V+G   Y Q KS+     +YGKWTE L++  P  ++        +DS++S  +    D++            + D       P   +L      W+  PRP NSA  YNFT+F + LN+        +P TD R R D+R ME G +D A+  K  LEEKQRA R +   +                   +++    WF +  NPY    +W ++G YW+R++S  PDI+
Sbjct:   88 RTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLSEYMEHTYLIHKANQCSDTVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVREDLGFRLISEQVSHHPPVSAFHAEGINNDFVFHGSIYPKLKFWGKSVEAEPKGIITLELLKHKEAYTWTNPTCCVHNIIVGKLWIEQYGNMEITNHKTGEKCILNFKPSRLFDKELHKVEG---YIQDKSKKKLCSLYGKWTECLYTTDPATFDAFKKNDKKEDSTSSAGNAEEPDEM-----------PLPDSESVQVIPGSTQL------WRIAPRPPNSAQMYNFTNFALALNEFDKDMEGTIPKTDCRLRPDIRAMENGEIDSASEEKKRLEEKQRAARKSRSKT-------------------DEEWKTRWFRQGPNPYNGSQDWLYSGNYWDRNYSNLPDIY 500          

Query:  233 RTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLI---------WKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            +  LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRL+EY+E++ L+ +A   +D ++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPPVSAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLELL   E YTW N  C VHN+I+GK+WIE  G M I NH       L F     F K +H+V+G   Y Q KS+     +YGKWTE L++  P  ++      K+ V                            P +M L +   +         W+  PRP NSA  YNFT+F + LN+        +P TD R R D+R ME G +D A+  K  LEEKQRA R +   +                   +++    WF +  NPY    +W ++G YW+R++S  PDI+
Sbjct:  142 KHSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLSEYMEHTYLIHKANQCSDTVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVREDLGFRLISEQVSHHPPVSAFHAEGINNDFVFHGSIYPKLKFWGKSVEAEPKGIITLELLKHKEAYTWTNPTCCVHNIIVGKLWIEQYGNMEITNHKTGEKCILNFKPSRLFDKELHKVEG---YIQDKSKKKLCSLYGKWTECLYTTDPATFDAFKKNDKKEVEEKQ-------------VKVKQAGNAEEPDEMPLPDSESVQVIPGSTQLWRIAPRPPNSAQMYNFTNFALALNEFDKDMEGTIPKTDCRLRPDIRAMENGEIDSASEEKKRLEEKQRAARKSRSKT-------------------DEEWKTRWFRQGPNPYNGSQDWLYSGNYWDRNYSNLPDIY 559          

Query:  233 RTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRL+EY+E++ L+ +A   +D ++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPPVSAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLELL   E YTW N  C VHN+I+GK+WIE  G M I NH       L F     F K +H+V+G   Y Q KS+     +YGKWTE L++  P  ++      K+ V   ++ +   K + +   + D       P   +L      W+  PRP NSA  YNFT+F + LN+        +P TD R R D+R ME G +D A+  K  LEEKQRA R +   +                   +++    WF +  NPY    +W ++G YW+R++S  PDI+
Sbjct:  422 RTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLSEYMEHTYLIHKANQCSDTVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVREDLGFRLISEQVSHHPPVSAFHAEGINNDFVFHGSIYPKLKFWGKSVEAEPKGIITLELLKHKEAYTWTNPTCCVHNIIVGKLWIEQYGNMEITNHKTGEKCILNFKPSRLFDKELHKVEG---YIQDKSKKKLCSLYGKWTECLYTTDPATFDAFKKNDKKEV---EEKQVKVKQEPDEMPLPDSESVQVIPGSTQL------WRIAPRPPNSAQMYNFTNFALALNEFDKDMEGTIPKTDCRLRPDIRAMENGEIDSASEEKKRLEEKQRAARKSRSKT-------------------DEEWKTRWFRQGPNPYNGSQDWLYSGNYWDRNYSNLPDIY 834          

Query:  215 NHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            N I  +RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRL+EY+E++ L+ +A   +D ++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPPVSAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLELL   E YTW N  C VHN+I+GK+WIE  G M I NH       L F     F K +H+V+G   Y Q KS+     +YGKWTE L++  P  ++      K+   + ++ +           + D       P   +L      W+  PRP NSA  YNFT+F + LN+        +P TD R R D+R ME G +D A+  K  LEEKQRA R +   +                   +++    WF +  NPY    +W ++G YW+R++S  PDI+
Sbjct:  469 NGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLSEYMEHTYLIHKANQCSDTVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVREDLGFRLISEQVSHHPPVSAFHAEGINNDFVFHGSIYPKLKFWGKSVEAEPKGIITLELLKHKEAYTWTNPTCCVHNIIVGKLWIEQYGNMEITNHKTGEKCILNFKPSRLFDKELHKVEG---YIQDKSKKKLCSLYGKWTECLYTTDPATFDAFKKNDKKEAGNAEEPD--------EMPLPDSESVQVIPGSTQL------WRIAPRPPNSAQMYNFTNFALALNEFDKDMEGTIPKTDCRLRPDIRAMENGEIDSASEEKKRLEEKQRAARKSRSKT-------------------DEEWKTRWFRQGPNPYNGSQDWLYSGNYWDRNYSNLPDIY 882          

Query:  215 NHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLI---------WKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            N I  +RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRL+EY+E++ L+ +A   +D ++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPPVSAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLELL   E YTW N  C VHN+I+GK+WIE  G M I NH       L F     F K +H+V+G   Y Q KS+     +YGKWTE L++  P  ++      K+ V    Q++  + G+               P +M L +   +         W+  PRP NSA  YNFT+F + LN+        +P TD R R D+R ME G +D A+  K  LEEKQRA R +   +                   +++    WF +  NPY    +W ++G YW+R++S  PDI+
Sbjct:  533 NGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLSEYMEHTYLIHKANQCSDTVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVREDLGFRLISEQVSHHPPVSAFHAEGINNDFVFHGSIYPKLKFWGKSVEAEPKGIITLELLKHKEAYTWTNPTCCVHNIIVGKLWIEQYGNMEITNHKTGEKCILNFKPSRLFDKELHKVEG---YIQDKSKKKLCSLYGKWTECLYTTDPATFDAFKKNDKKEVEEK-QVKVKQAGNAEE------------PDEMPLPDSESVQVIPGSTQLWRIAPRPPNSAQMYNFTNFALALNEFDKDMEGTIPKTDCRLRPDIRAMENGEIDSASEEKKRLEEKQRAARKSRSKT-------------------DEEWKTRWFRQGPNPYNGSQDWLYSGNYWDRNYSNLPDIY 956          

Query:  200 GQHGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            G    N I  +RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRLTEY+E++ L+ +A + +DP++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLELL  NE YTW N  C VHN+I+GK+WIE  G + IINH       L F   G FGK +H+V+G   Y Q KS+     +YGKWTE L+SV P  ++      K++       E       ++++  D +P  ++     +    L+W+  PRP NSA  YNFTSF M LN++       +P TD R R D+R ME G +D A+  K  LEEKQRA R               S S E    R       WF +  NPY+   +W ++G YW+R++   PDI+
Sbjct:   10 GDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLDHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEG---YIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTE-----EKKNSKQTSSSEESDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKEMESVIPKTDCRLRPDIRAMENGEIDLASEEKKRLEEKQRAAR------------KNRSKSEEDWKTR-------WFHQGPNPYSGAQDWIYSGSYWDRNYFNLPDIY 437          

Query:  200 GQHGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            G    N I  +RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRLTEY+E++ L+ +A + +DP++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLELL  NE YTW N  C VHN+I+GK+WIE  G + IINH       L F   G FGK +H+V+G   Y Q KS+     +YGKWTE L+SV P  ++      K++       E       ++++  D +P  ++     +    L+W+  PRP NSA  YNFTSF M LN++       +P TD R R D+R ME G +D A+  K  LEEKQRA R               S S E    R       WF +  NPY+   +W ++G YW+R++   PDI+
Sbjct:   10 GDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLDHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEG---YIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTE-----EKKNSKQTSSSEESDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKEMESVIPKTDCRLRPDIRAMENGEIDLASEEKKRLEEKQRAAR------------KNRSKSEEDWKTR-------WFHQGPNPYSGAQDWIYSGSYWDRNYFNLPDIY 437          

Query:  200 GQHGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            G    N I  +RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRLTEY+E++ L+ +A + +DP++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLELL  NE YTW N  C VHN+I+GK+WIE  G + IINH       L F   G FGK +H+V+G   Y Q KS+     +YGKWTE L+SV P  ++      K++       E       ++++  D +P  ++     +    L+W+  PRP NSA  YNFTSF M LN++       +P TD R R D+R ME G +D A+  K  LEEKQRA R               S S E    R       WF +  NPY+   +W ++G YW+R++   PDI+
Sbjct:   10 GDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLDHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEG---YIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTE-----EKKNSKQTSSSEESDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKEMESVIPKTDCRLRPDIRAMENGEIDLASEEKKRLEEKQRAAR------------KNRSKSEEDWKTR-------WFHQGPNPYSGAQDWIYSGSYWDRNYFNLPDIY 437          

Query:  200 GQHGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            G    N I  +RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRLTEY+E++ L+ +A + +DP++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLELL  NE YTW N  C VHN+I+GK+WIE  G + IINH       L F   G FGK +H+V+G   Y Q KS+     +YGKWTE L+SV P  ++      K++       E       ++++  D +P  ++     +    L+W+  PRP NSA  YNFTSF M LN++       +P TD R R D+R ME G +D A+  K  LEEKQRA R               S S E    R       WF +  NPY+   +W ++G YW+R++   PDI+
Sbjct:   10 GDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLDHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEG---YIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTE-----EKKNSKQTSSSEESDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKEMESVIPKTDCRLRPDIRAMENGEIDLASEEKKRLEEKQRAAR------------KNRSKSEEDWKTR-------WFHQGPNPYSGAQDWIYSGSYWDRNYFNLPDIY 437          

Query:  200 GQHGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            G    N I  +RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRLTEY+E++ L+ +A + +DP++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLELL  NE YTW N  C VHN+I+GK+WIE  G + IINH       L F   G FGK +H+V+G   Y Q KS+     +YGKWTE L+SV P  ++      K++       E       ++++  D +P  ++     +    L+W+  PRP NSA  YNFTSF M LN++       +P TD R R D+R ME G +D A+  K  LEEKQRA R               S S E    R       WF +  NPY+   +W ++G YW+R++   PDI+
Sbjct:   10 GDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLDHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEG---YIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTE-----EKKNSKQTSSSEESDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKEMESVIPKTDCRLRPDIRAMENGEIDLASEEKKRLEEKQRAAR------------KNRSKSEEDWKTR-------WFHQGPNPYSGAQDWIYSGSYWDRNYFNLPDIY 437          

Query:  212 DNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKR--HVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            +N I  +RT LP PM ++ +FSVW+ LK+CIG ELSKITMPI FNEP+SFLQR+TEY+E+  L+ +A +++ P++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+++SEQ+ HHPP+SAF+ E  +  F+F+G+I+PKL FWGKSV   P+G ITLELL  NE YTW N  C VHNVI+G++WIE  G + I+NH       L F   G FGK +HRV+G   Y Q K+R     +YGKWTE L+ + P  +       KR          +  EK +++                  +   +L+W+   RP NSA  YNFTSFT+ LN++     + LPPTD R R D+R ME G +D A+  K  LEEKQR  R                 + E  + R +     WF+   NPYT   +W + G Y+ R++S CPDI+
Sbjct:   54 ENGIQKHRTALPAPMFTRSDFSVWSILKKCIGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHKASSQSQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFYSEGLNQDFRFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVILGQLWIEQYGIVEIVNHRTGDKCILHFKPCGLFGKELHRVEG---YIQDKNRKKLFIMYGKWTECLWGIDPASYESFKKQEKRGDQARKAKMDDGPEKANSDVPGDVADDVPVAQETVQVIPGSKLLWRINSRPPNSAQMYNFTSFTVSLNELESGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREAR--------------KERAKEDAEWRTR-----WFSPGNNPYTGAPDWLYAGHYFERNFSDCPDIY 484          

Query:  212 DNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPT--FKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKR--HVNST--DQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEG---PVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            +N I  +RT LP PM S+ +FSVWT LK+C+G ELSKITMPI FNEP+SFLQR+TEY+E+  L+ +A  +  P++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+++SEQ+ HHPP+SAFH E     F F+G+I+PKL FWGKSV   P+G ITLELL  NE YTW N  C VHNVIIGK+WIE  G + I+NH       L F   G FGK +H+V+G I   Q K++     +YGKWTE L+ + P  +       +R  H+     D+       D  ++           P        +L+W+   RP NSA  YNFTSFT+ LN++     + LPPTD R R D+R ME G +D A+  K  LEEKQR  R                        R ++E      WF    NPYT   +W + G+Y+ R++S CPDI+
Sbjct:   54 ENGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHI---QDKNKKKLFMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIP------GSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRE----------------------RAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY 480          

Query:  200 GQHGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPT--FKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            G    N I  +RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRLTEY+E++ L+ +A + +DP++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH E     F F+G+I+PKL FWGKSV   PKG ITLELL  NE YTW N  C VHN+I+GK+WIE  G + IINH       L F   G FGK +H+V+G   Y Q KS+     +YGKWTE L+SV P  ++      K++       E       + ++  D +P  ++     +    L+W+  PRP NSA  YNFTSF M LN++       +P TD R R D+R ME G +D+A+  K  LEEKQRA R               S S E    R       WF +  NPY+   +W ++G YW+R++   PDI+
Sbjct:  523 GDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSFSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEG---YIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTE-----EKKTSKQASTSEESDEMPVPDSESVFVIPGSALLWRIAPRPPNSAQMYNFTSFAMVLNEVDKEMETVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAAR------------KNRSKSEEDWKTR-------WFHQGPNPYSGAQDWIYSGSYWDRNYFNLPDIY 950          

Query:  185 AEDENGQHGD---NHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            +E+++   GD   N I  +RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRLTEY+E++ L+ +A + +DP++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLELL  NE YTW N  C VHN+I+GK+WIE  G + IINH       L F   G FGK +H+V+G   Y Q KS+     +YGKWTE L+SV P  ++      K++       E       + ++  D +P  ++     +    L+W+  PRP NSA  YNFTSF M LN++       +P TD R R D+R ME G +D+A+  K  LEEKQRA R               S S E    R       WF +  NPY    +W ++G YW+R++   PDI+
Sbjct:  515 SEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEG---YIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTE-----EKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAAR------------KNRSKSEEDWKTR-------WFHQGPNPYNGAQDWIYSGSYWDRNYFNLPDIY 950          

Query:  200 GQHGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPT--FKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            G    N I  +RT LP PM S+ +FS+W+ L++CIG ELSKITMP++FNEP+SFLQRLTEY+E++ L+ +A + +DP++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH E     F F+G+I+PKL FWGKSV   PKG ITLELL  NE YTW N  C VHN+I+GK+WIE  G + IINH       L F   G FGK +H+V+G   Y Q KS+     +YGKWTE L+SV P  ++      K++       E       ++++  D +P  ++     +    L+W+  PRP NSA  YNFTSF M LN++       +P TD R R D+R ME G +D A+  K  LEEKQRA R               S S E    R       WF +  NPY+   +W ++G YW+R++   PDI+
Sbjct:  523 GDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLDHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEG---YIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTE-----EKKNSKQTSSSEESDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKEMESVIPKTDCRLRPDIRAMENGEIDLASEEKKRLEEKQRAAR------------KNRSKSEEDWKTR-------WFHQGPNPYSGAQDWIYSGSYWDRNYFNLPDIY 950          

Query:  254 MPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRP--NFKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPC------DMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEG---PVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            M S  +FS+W+ LKQCIGKELSKITMP+VFNEP+SFLQRLTEY+EYS LLD+A   +DPI+R++ + AFAVS  +SNW R+GKPFNPLLGETYEL R    F+ +SEQ+ HHPP+SAFH++SP +KF+G I+PKL FWGKSV I PKG +TLEL  +NEVYTWQNV C VHN+I+GK+W+EHSGPM IINH     A L F   GWFGK++H+V+G IY   +K     + ++G W   LFSV+   ++   +        T ++             D     D  PC      D+ +  Q  +W+A PRP++SA +++FT F M LN++    +  LPPTDSR R D+RY+EEG +DEAA+AKN LEEKQR  R                        R +++G   P+WF    N YT K EW + G+YW RD+S C DIF
Sbjct:    1 MFSSRDFSLWSILKQCIGKELSKITMPVVFNEPLSFLQRLTEYMEYSYLLDRASQTSDPIERLQYVSAFAVSAISSNWERLGKPFNPLLGETYELDRSELGFRLISEQVSHHPPISAFHIDSPLYKFHGQIYPKLKFWGKSVDIHPKGYVTLELKKFNEVYTWQNVNCCVHNIIVGKLWVEHSGPMEIINHQTKHRAVLNFKQGGWFGKDLHKVEGYIYDPDKKKL---KAIWGNWLMGLFSVNAGTYDAHVAAMPSSPPHTPKVN--------GAGGDAEDASDELPCKSFNSFDLNIPGQITLWQATPRPEDSAKYFSFTLFAMTLNEMMPEMNITLPPTDSRKRPDIRYLEEGKIDEAADAKNRLEEKQRQARKE----------------------RKKQKGDWQPLWFETVKNQYTGKEEWAYKGDYWERDFSKCGDIF 411          

Query:  224 YTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKE-GPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            + +R  LPKPM S+ +FSVW+ LKQCIGKELSKITMP++FNEP+SF+QR+ EY+EY+ LL  A    DP++R+E + AFAVS  ASNW RIGKPFNPLLGETY+L R +  F+   EQ+ HHPPVSAFHV+SP ++F G++ PKL FWGKSV +TPKG +TL L   NE ++WQNV C VHN+I+GKIW+EH G M ++NHS    A L F   GWFGK++H+V+G I    +K     R  YGKW EA++S  PE  +  +S    H + + Q              +D   + ++ CD+ +  QRL+W A PRP +S  +Y FT F M LN++ DS   +L PTDSR R D+R MEEG +D AA  KN LEEKQRA R   K                    +++ E  P+WF  + NP+T + +W   G++W+ DW   PDIF
Sbjct:  501 FNFRCHLPKPMISRHDFSVWSILKQCIGKELSKITMPVIFNEPLSFVQRIVEYMEYANLLKLADQCDDPVQRLEYVTAFAVSATASNWDRIGKPFNPLLGETYQLERDDLGFRIYCEQVSHHPPVSAFHVDSPIYEFSGSVLPKLKFWGKSVEVTPKGIVTLHLKRHNETFSWQNVNCCVHNIIVGKIWVEHYGGMEVMNHSTKQKASLHFKPSGWFGKDLHKVEGCILDQNKKKL---RSFYGKWVEAIYSCDPESLDIQTS---HHADESYQ------------PPEDSPQKGSSSCDLGIPGQRLLWSALPRPVDSEEYYAFTLFAMMLNELPDSLRSQLAPTDSRLRPDIRRMEEGDIDGAAIEKNRLEEKQRAVRKERK--------------------KSKSEWKPLWFEHRANPHTGREDWVSNGKFWDGDWQGSPDIF 908          

Query:  194 ENGQHGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            E+G   D+  Y YR+ LP PM  + +FS+W+ LKQCIGKELSKITMP+VFNEP+SF+QR++EY+EY+ LL++A   +DP +R   + AFAVS  +SNW RIGKPFNPLLGET+EL+R +  F+ V EQ+ HHPPVSAF VES  FK +G+IHPKL FWGKSV I PKG ITLEL    EVYTW NV C VHNVI+GKIWIEH G M I+ H     + L F   GWFGK++H+V+G +Y   +  R   + +YG W   LF +    + D    +     S            +++  DD   +  +  D+ +  Q  IW   PRP+ S  +++FT F M LN++T   + +L PTDSR R D+R +EEG +D AA  KN +EEKQR  R   K                    R  +  PV+F    NP+T K +W F G YW+RDWS CPDIF
Sbjct:   12 EDGNDSDDR-YIYRSRLPVPMFDRNDFSIWSILKQCIGKELSKITMPVVFNEPLSFIQRISEYMEYTSLLEKASMASDPAERFAYVSAFAVSAISSNWDRIGKPFNPLLGETFELNRSDLGFRLVGEQVSHHPPVSAFLVESKHFKIHGSIHPKLKFWGKSVEINPKGMITLELTRHGEVYTWSNVNCCVHNVIVGKIWIEHYGVMEILCHKTGWKSVLNFKQSGWFGKDLHKVEGYVYDKNKVKR---KALYGSWVYDLFMLDVADY-DGFMKNSASTQSPSHSAKSNGASGSSDVNDDISVKHLSTYDLHIPGQECIWTIHPRPEKSLQYFSFTLFAMALNELTPDIAGQLAPTDSRLRPDIRLLEEGQIDAAAAEKNRIEEKQRFARKERKR-------------------RKDEWTPVFFKFGTNPHTGKEDWLFKGNYWDRDWSKCPDIF 442          

Query:  230 YRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPNFKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTE-------ALFSV--------------SPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXX-------XXXXXXXTPCD----MKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            +R  LP PM S+ +FS+W+ LK  IGKELS I MP+VFNEP+SFLQR+ EY+EY+ LL  A  ++DP+ RM+ + AFAVS  ASNW R+GKPFNPLLGETYEL RP F+ V EQ+ HHPPVSAFH +S  F F+G+IHPKL FWGKSV I PKG +T+EL  W E YTW NV C VHNVI+GK+WIE  G M I+NHS    A LTF   GWF K++HRV+G I   Q+K  +    +YGKWTE       A + V              +P   +  + T K+ +   +  +       + +  +            D   CD    + + N   IW+ +PRP+NS+ FY FT F M LN+I     R L PTD R R D+R +E+G LD AA+ K  LEEKQR  R A                    + + Q+  P WF +  NPYT + +W + G YW+R++S  P IF
Sbjct:   11 HRRSLPMPMFSRNDFSLWSVLKTSIGKELSNIAMPVVFNEPLSFLQRMVEYMEYAHLLRYAAEQSDPLARMQYVAAFAVSALASNWERLGKPFNPLLGETYELERPEFRVVCEQVSHHPPVSAFHADSEHFIFHGSIHPKLKFWGKSVEIQPKGVVTVELPKWGEAYTWTNVNCCVHNVIVGKLWIEQYGTMEILNHSTGHRAVLTFKPAGWFSKDLHRVEGFIMDKQKKKYYF---IYGKWTEFIKITDFASYEVYAKDNADKFRSDGKAPNFSDSPAHTPKKVLAKLNSFKMGSFKSMSMSVAEPDEGCEDGAEGGDIPKCDSTYSIDIPNSTTIWECEPRPENSSEFYQFTFFAMSLNEIESGMERRLCPTDCRLRPDVRKLEQGDLDGAASEKTRLEEKQRETRKAR------------------KNKKGQEWVPRWFCQGANPYTGQDDWLYAGGYWDRNYSNSPTIF 462          

Query:  224 YTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPNFKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFS---VSPEVWNDDS-------------STSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCD----------------MKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEG----PVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            + +R  LP PM S+ +FS+W+ LK  IGKELS I MP+VFNEP+SFLQR+ EY+EY+ LL  A  ++DP+ RM+ + AFAVS  ASNW R+GKPFNPLLGETYEL RP F+ V EQ+ HHPPVSAFH +S  F F+G+IHPKL FWGKSV I PKG +T+EL  W E YTW NV C VHNVI+GK+WIE  G M IINHS    A LTF   GWF K++HRV+G I   Q+K  +    +YGKWTE +      S E++  D+             S S  H       + +     +   +   + + +  C+                + + N   +W+ +PRP+NS+ FY FT F M LN+I     + L PTD R R D+R +E+G LD AA+ K  LEEKQR  R A                      R  K+G    P WF +  NPYT + +W + G YW+R++S  P IF
Sbjct:   10 HQFRRSLPMPMFSRNDFSLWSVLKTSIGKELSNIAMPVVFNEPLSFLQRMVEYMEYAHLLRYAAEQSDPLARMQYVAAFAVSALASNWERLGKPFNPLLGETYELERPEFRVVCEQVSHHPPVSAFHADSEHFIFHGSIHPKLKFWGKSVEIQPKGVVTVELPKWGEAYTWTNVNCCVHNVIVGKLWIEQYGTMEIINHSTGHRAVLTFKPAGWFSKDLHRVEGFIMDKQKKKYYF---IYGKWTEFIKVTDFASYEIYAKDNADKFRSDGKAPNFSDSPAHTPKKVLAKLNSFKMGSFKSMSMSVAEPDEGCEDGAEGGDIPKCDSTYSIDIPNSTTLWECEPRPENSSEFYQFTFFAMSLNEIEPGMEKRLCPTDCRLRPDIRKLEQGDLDGAASEKTRLEEKQREARKA----------------------RKNKKGQEWIPRWFCQGANPYTGQDDWLYAGSYWDRNFSNSPSIF 463          

Query:  185 AEDENGQ-HGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            AE  NG    +N I   R+GLP PM S+ NFSVW+ LK+CIG ELSKITMPIVFNEP+SFLQR+TEY+E++ L+ +A   +D I RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH E  S  F F+G+I+PKL FWGKSV   PKG ITLELL   E YTW N  C VHNVI+GK+WIE  G + I+NHS      L F   G FGK +HRV+G I    +K R V   +YGKWTE ++SV P+V+       K+    T + + +E     N D DD      T     +    L+W+  PRP NSA  YNFT+FT+ LN++       L PTD R R D+R ME G +DEA+  K  LEEKQRA R                         +++    WF    NPYT   +W +TG Y++R ++ CPDI+
Sbjct:   89 AEKNNGTIPQENGIKKRRSGLPAPMFSRNNFSVWSILKKCIGLELSKITMPIVFNEPLSFLQRITEYMEHTYLIHKACTLSDSIDRMQAVAAFAVSAVASQWDRTGKPFNPLLGETYELTREDQGFRLISEQVSHHPPISAFHAEGLSQDFLFHGSIYPKLKFWGKSVEAEPKGTITLELLKHKEAYTWSNPFCCVHNVIVGKLWIEQYGTVEIVNHSTGDKCVLNFKPCGMFGKELHRVEGYIQDKSKKKRCV---IYGKWTECMWSVDPQVYESHRKNDKKGTTDTKKQKPEEAEVAENEDADDMPEVQETVA--VIPGSTLLWRVSPRPPNSAEMYNFTNFTITLNELEPGMEGVLAPTDCRLRPDIRAMENGDMDEASREKERLEEKQRAARKERAKD-------------------SEEWSTRWFELATNPYTGSQDWLYTGGYFDRKYTDCPDIY 525          

Query:  185 AEDENGQ-HGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            AE  NG    +N I   R+GLP PM S+ NFSVW+ LK+CIG ELSKITMPIVFNEP+SFLQR+TEY+E++ L+ +A   +D I RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH E  S  F F+G+I+PKL FWGKSV   PKG ITLELL   E YTW N  C VHNVI+GK+WIE  G + I+NHS      L F   G FGK +HRV+G I    +K R V   +YGKWTE ++SV P+V+       K+    T + + +E     N D DD      T     +    L+W+  PRP NSA  YNFT+FT+ LN++       L PTD R R D+R ME G +DEA+  K  LEEKQRA R                         +++    WF    NPYT   +W +TG Y++R ++ CPDI+
Sbjct:  106 AEKNNGTIPQENGIKKRRSGLPAPMFSRNNFSVWSILKKCIGLELSKITMPIVFNEPLSFLQRITEYMEHTYLIHKACTLSDSIDRMQAVAAFAVSAVASQWDRTGKPFNPLLGETYELTREDQGFRLISEQVSHHPPISAFHAEGLSQDFLFHGSIYPKLKFWGKSVEAEPKGTITLELLKHKEAYTWSNPFCCVHNVIVGKLWIEQYGTVEIVNHSTGDKCVLNFKPCGMFGKELHRVEGYIQDKSKKKRCV---IYGKWTECMWSVDPQVYESHRKNDKKGTTDTKKQKPEEAEVAENEDADDMPEVQETV--AVIPGSTLLWRVSPRPPNSAEMYNFTNFTITLNELEPGMEGVLAPTDCRLRPDIRAMENGDMDEASREKERLEEKQRAARKERAKD-------------------SEEWSTRWFELATNPYTGSQDWLYTGGYFDRKYTDCPDIY 542          

Query:  164 DPEEYFDAEDENGQ-HGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPT--FKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            D   Y   +  NG+ H +N ++  RT LP PM S+ +FS+W FLK+CIG ELSKITMPIVFNEP+SFLQR++EY+E++ L+ +A   +D I+RM+ + AFAVS  AS W R GKPFNPLLGET+EL R +  ++ +SEQ+ HHPP+SAF+ ES +  F F+G+I+PKL FWGKSV   PKG +TLEL    E YTW N +C VHNVI+GK+WIE  G + I+NHS      L F   G FGK +HRV+G   Y Q KS+   R +YGKWTE L+++ P+V+  +    K+  +S    +  + G + ++  + P  Q+       +    L+W+  PRP +SA  YNFTSF M LN+++      LPPTD R R D+R ME G +D A+  K  LEEKQRA R             + +   E    R       WF +  NP+    +W + G Y++R +S  PDI+
Sbjct:   26 DAPVYEGKQTSNGRMHSENGVWERRTTLPAPMFSRNDFSIWGFLKKCIGMELSKITMPIVFNEPLSFLQRISEYMEHTYLIHKACTLSDSIERMQVVAAFAVSAVASQWDRTGKPFNPLLGETFELTREDEGYRLISEQVSHHPPISAFYAESLSQDFVFHGSIYPKLKFWGKSVEAEPKGIMTLELSKHKEAYTWTNPMCCVHNVILGKLWIEQYGTVEIVNHSTGDKCVLNFKPCGMFGKELHRVEG---YIQDKSKKKRRIIYGKWTECLYTIEPKVYEANKKAEKKSGDSKKHKQEQKTGGSADDADEMPDVQETV---TMIPGSTLLWRIAPRPAHSAQMYNFTSFAMTLNELSPGMEEVLPPTDCRLRPDIRAMENGDMDTASLEKERLEEKQRAAR------------RERAKDEEDWSTR-------WFHQGTNPHLGSSDWIYQGGYFDRKYSDLPDIY 468          

Query:  170 EEYFDAEDENGQHGDNHIYT------YRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPT--FKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            EE++DAE      G N +        YRT LP PM S+ +FS+W FLK+CIG ELSKITMPIVFNEP+SFLQR++EY+E++ L+ +A   +D I+RM+ + AFAVS  AS W R GKPFNPLLGET+EL R +  ++ +SEQ+ HHPP+SAF+ ES +  F F+G+I+PKL FWGKSV   PKG +TLEL    E YTW N +C VHNVI+GK+WIE  G + I+NHS      L F   G FGK +HRV+G   Y Q KS+   R +YGKWTE L+++ P+V+  +    K+  +S    +      ++ +++ D            +    L+W+  PRP +SA  YNFTSF M LN+++      LPPTD R R D+R ME G +D A+  K  LEEKQRA R             + +   E    R       WF +  NP+    +W + G Y++R +S  PDI+
Sbjct:    5 EEFYDAET-----GGNTMCVFVPFLFYRTTLPAPMFSRNDFSIWGFLKKCIGMELSKITMPIVFNEPLSFLQRISEYMEHTYLIHKACTLSDSIERMQVVAAFAVSAVASQWDRTGKPFNPLLGETFELTREDEGYRLISEQVSHHPPISAFYAESLSQDFVFHGSIYPKLKFWGKSVEAEPKGIMTLELSKHKEAYTWTNPMCCVHNVILGKLWIEQYGTVEIVNHSTGDKCVLNFKPCGMFGKELHRVEG---YIQDKSKKKRRIIYGKWTECLYTIEPKVYEANKKAEKKSGDSKKHKQKTGGSADDADEMPDVQETVTM-----IPGSTLLWRIAPRPAHSAQMYNFTSFAMTLNELSPGMEEVLPPTDCRLRPDIRAMENGDMDTASLEKERLEEKQRAAR------------RERAKDEEDWSTR-------WFHQGTNPHLGSSDWIYQGGYFDRKYSDLPDIY 443          

Query:  185 AEDENGQ-HGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKR 1357
            AE  NG    +N I   R+GLP PM S+ NFSVW+ LK+CIG ELSKITMPIVFNEP+SFLQR+TEY+E++ L+ +A   +D I RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPP+SAFH E  S  F F+G+I+PKL FWGKSV   PKG ITLELL   E YTW N  C VHNVI+GK+WIE  G + I+NHS      L F   G FGK +HRV+G I    +K R V   +YGKWTE ++SV P+V+       K+    T + + +E     N D DD      T     +    L+W+  PRP NSA  YNFT+FT+ LN++       L PTD R R D+R ME G +DEA+  K  LEEKQRA R
Sbjct:  106 AEKNNGTIPQENGIKKRRSGLPAPMFSRNNFSVWSILKKCIGLELSKITMPIVFNEPLSFLQRITEYMEHTYLIHKACTLSDSIDRMQAVAAFAVSAVASQWDRTGKPFNPLLGETYELTREDQGFRLISEQVSHHPPISAFHAEGLSQDFLFHGSIYPKLKFWGKSVEAEPKGTITLELLKHKEAYTWSNPFCCVHNVIVGKLWIEQYGTVEIVNHSTGDKCVLNFKPCGMFGKELHRVEGYIQDKSKKKRCV---IYGKWTECMWSVDPQVYESHRKNDKKGTTDTKKQKPEEAEVAENEDADDMPEVQETV--AVIPGSTLLWRVSPRPPNSAEMYNFTNFTITLNELEPGMEGVLAPTDCRLRPDIRAMENGDMDEASREKERLEEKQRAAR 496          

Query:  233 RTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVW-----NDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            RT LP PM S+ NFS+W+FL++CIG ELSKITMP++FNEP+SFLQRL EY+E++ L+ +A   +  I+RM+ + AFAVS  ASNW R GKPFNPLLGETYE+ R +  F+ VSEQ+ HHPP+SAF  E  +  F F+G+++PKL FWGKSV   P+G ITLEL  + E YTW N  C VHNVI+GK+WIE  G + I NH     A L+F +     +   R         +K   V   +YGKWTE L+SV P ++     ND  ST K       +           ++ DD    +       L   +L+W+  PRP NS   YNFTSF + LN++       L PTD R R DM+ ME+G +D A   KN LEEKQRA R             + + + E    R       WF + LNP+T+  +W + G Y++R +  CP+IF
Sbjct:    1 RTSLPAPMFSRSNFSIWSFLRRCIGMELSKITMPVIFNEPLSFLQRLCEYMEHTYLIHKANTSSSSIERMQCVAAFAVSAVASNWERTGKPFNPLLGETYEMVREDLGFRLVSEQVSHHPPISAFFAEGLNKDFVFHGSVYPKLKFWGKSVEAEPRGIITLELPRYGEAYTWTNPSCCVHNVIVGKLWIEQYGTVEITNHKRGFKASLSFRARNITKRKSRRPLSAFRIDSKKKVSV---IYGKWTEVLWSVDPGIYEVGKKNDKKSTEKLAKLVAAESSGPSGQQAEADEADDIPTPEVPETVTVLPGSKLLWRVHPRPANSTQMYNFTSFALTLNEMEKEMEGLLAPTDCRLRPDMKAMEQGDIDLAGEEKNRLEEKQRAAR------------KQRAKTEEEWHTR-------WFRQDLNPHTSTADWIYAGNYFDRRYENCPNIF 427          

Query:  161 TDPEEYFDAEDENGQHGDNHIYT-YRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIG-KPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIIN-HSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKR 1357
            T     F ++  NG   +    T  R  LP P     +  +W  L++ IGK+LSK+ MP+  NEP++ LQRL E +EYS+LLD+A    DP +RM  +  FAVS  AS   R G KPFNP+LGETYE  R +  F++++EQ+ HHPP+S  H +S  F  +  +  K  FWGKS+ I P G + ++LL + + Y W  V   +HN++ G+ WIEH G + I N  SN C   + F    ++    ++V G +     +  H   +++GKW E ++  +                                                  + R IW+    P +  ++Y FT F + LN++       LPPTD+RFR D R++EEG ++ A   K  +EE QR KR
Sbjct:  494 TGSRASFKSQQSNGAFTNREFQTGRRMHLPAPAADTSSIGLWDILRKNIGKDLSKVAMPVELNEPLNVLQRLCEEMEYSDLLDRAADTDDPAQRMVLVATFAVSTYASTISRAGGKPFNPVLGETYECIREDRGFRFIAEQVSHHPPISVCHCDSKKFVLWQDVRLKNKFWGKSMEIIPVGTVNVKLLKYGDEYEWNKVTSCIHNIMGGQRWIEHYGEVIIKNKKSNVCQCKINFIKASYWSSEANQVQGTVMDQNGRVLH---RLFGKWNEGMYCGAQR------------------------------------------------SARCIWRPGSLPQDHELYYGFTRFAIELNELDPVLRPHLPPTDTRFRPDQRFLEEGNMESAQREKLRIEEFQREKR 846          

Query:  254 MPSKLNFSV--WTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHR---PNFKYVSEQICHHPPVSAFHVESPT-FKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHR-VDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYW----NRDWSVCPDIF 1552
            +P K N+S+  W+ +K CIGK+LSKI MP+ FNEP+S LQRLTE +EY +LLD+A      ++++  + AF+VS  ++   R GKPFNPLLGET+EL R     ++ + EQ+ HHPP +A HV+S   ++ +  I     F GK + I P G I  E       YTW+ V  TVHN+I+G++WI+ SG + I+NH       L F +  +F +++ R V G +   +  + ++   + G W E +        +  SS S+    +  Q +                              + +WK  P P+NS   Y FT   + LN+  +     + PTDSR R D R ME G  DEA   K  LEEKQR     L     +  +  ++  +     ++Q   P+WF  K +P+T ++   + G YW     ++W +  DIF
Sbjct:  338 IPDKPNYSLNLWSIMKNCIGKDLSKIPMPVNFNEPLSMLQRLTEDLEYFDLLDKAAKCESSLEQLCYVAAFSVSSYSTTVYRTGKPFNPLLGETFELDRLEECGYRSICEQVSHHPPAAAHHVDSRRGWRLWQEITVSSKFRGKYLSIIPLGTIHCEFPSSGNHYTWKKVTTTVHNIIVGRLWIDQSGDIDIVNHHTGDKCQLKFIAYSYFSRDIPRKVSGVVMDAEGNAHYI---LSGTWDEKMEYAKIVQSSKGSSGSEGRQKTVYQTQPA----------------------------KHLWKRYPLPENSDNMYYFTELALTLNETEEG----VAPTDSRLRPDQRLMENGKWDEANAEKQRLEEKQR-----LVRRRREAELASAAEPNGDAGRKHQSYRPMWFERKEDPFTREVSCVYRGGYWETKEKQEWKISQDIF 741          

Query:  233 RTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIG-KPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLEL 709
            R+ LP P P     S+W  L+  IGK+L+K++MP+  NEP++ LQRL E +EYSELL+QA    DP +RM    AFAVS  A  + R G KPFNP+LGETYE  R +  F++V+EQ+ HHPP+SA H ES TF  +  +  K  FWGKS+ I P G ++L L
Sbjct:  344 RSFLPAPCPDTSGVSLWNILRNNIGKDLAKVSMPVELNEPLNTLQRLCEELEYSELLEQASDTEDPAQRMVLAAAFAVSAYAPTYYRSGNKPFNPVLGETYECIREDKGFRFVAEQVSHHPPISACHCESKTFVLWQDVRWKNKFWGKSMEILPLGTVSLNL 505          

Query:  278 VWTFLKQCI-GKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYE---LH---RPNFKYVSEQICHHPPVSAFHVES--PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGK--NMHRVDGDIYYGQ 913
            +WT LKQ   G +LSK+ +P    EP SFL +L++Y  ++++L QA  E +   R++++  + +SG       + KP+NP++GET+    +H        Y+SEQ+ HHPP+SAF + +    F   G I  +  F+G S+     G   L  L   E Y           ++ G + +E  G + I     N  A++ F    + G   ++++V G I  G+
Sbjct:  337 IWTLLKQLRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADILSQAAVEENAYDRIKQVVRWYLSGFYKKPKGLKKPYNPIIGETFRCMWIHPQTSSKTYYISEQVSHHPPISAFFISNRKDGFCISGNILARSKFYGNSLSAILDGEGKLTFLNRGEEYLMTMPYAHCKGILYGTMTLELGGKIIIDCEKTNYKAEIEFKLKPFLGSSDSVNQVSGKIKLGK 559          

Query:  272 FSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWN----EVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYW----NRDWSVCPDIF 1552
             S+W  LK  +GK+++++T+P+ FNEP S LQR+ E +EYSELLDQA    D   R   + AF  S  AS   R+ KPFNPLLGET+E  RP+  +++ +EQ+ HHPP+SA   ESP + F+G       F G+S  +   G   ++L P +    E+YTW+    TV  ++IG   +++ G + ++NH+      L F + GW     + + G++Y  +++   +   + G W EA+F+    V + D S  K    ++                       N P D     + LIWKA  RP+     +N T F + LN         LPPTD+R R D R ME+G  DEA + K  +EEKQRA R                      +  N +  P WF    +P T    W++TG+YW    + D   C DIF
Sbjct:  896 ISLWAVLKSMVGKDMTRMTLPVTFNEPTSLLQRVAEDLEYSELLDQAATFEDSTLRTLYVAAFTASSYASTTKRVAKPFNPLLGETFEYSRPDKQYRFFTEQVSHHPPISATWTESPRWDFWGESFVDTKFNGRSFNVKHLGLWHIKLRPNDNEKEELYTWKKPNNTVIGILIGNPQVDNHGEVNVVNHTTGDHCKLYFKARGWRSSGAYEITGEVYNKKKQKVWI---LGGHWNEAIFA-KKVVKDGDLSLEKTRTAAS---------------------AGNGPTDDG--TKFLIWKANDRPEEP---FNLTPFAITLNAPQPHLLPWLPPTDTRLRPDQRAMEDGRYDEAGDEKFRVEEKQRAARRK-------------------REENNLEYHPQWFVRDTHPITKAKYWRYTGKYWVKRRDHDLKDCGDIF 1283          

Query:  233 RTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKS----------VVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQR-LIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNR----DWSVCPDIF 1552
            RT L     ++    +W+ LK  +G++L+K+T+P+ FNEP S LQR++E IEYS +LDQA    D   RM  + AF  S  AS   R+ KPFNPLLGET+E  R +  +++ +EQ+ HHPP+SA   ESP + FYG  +   +F G++          + I P  NI++      E Y+W+    TV  +++GK  +++SG +++ NH+      L + + GW     + V G+++    K   V   + G W ++++            T++    + D+I+                         KL   + LIWKA  RP   ++ +N TSF + LN +       L PTDSR R D R ME G  D+AA  K+ +E KQRA +                   +  + + ++  P WF ++ +P T  + W+F GEYWN+    D+  C DIF
Sbjct:  785 RTKLALDEDNRPKIGLWSVLKSMVGQDLTKLTLPVSFNEPTSLLQRVSEDIEYSHILDQAATFEDSSLRMLYVAAFTASMYASTTNRVSKPFNPLLGETFEYARTDGQYRFFTEQVSHHPPISATWTESPKWDFYGECNVDSSFNGRTFAVQHLGLWYITIRPDHNISVP----EETYSWKKPNNTVIGILMGKPQVDNSGDVKVTNHTTGDYCMLHYKAHGWTSAGAYEVRGEVFNKDDKKLWV---LGGHWNDSIYG--------KKVTARGGELTLDRIKTANSATGGP----------------KLDGSKFLIWKANERP---SVPFNLTSFALTLNALPPHLIPYLAPTDSRLRPDQRAMENGEYDKAAAEKHRVEVKQRAAK-------------------KEREQKGEEYRPKWFVQEEHPVTKSLYWKFNGEYWNKRKNHDFKDCADIF 1188          

Query:  227 TYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGA---SNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKR 1357
            T R  +P+   S    S+ +FL++ +GK+LS I MP+  NEPIS LQ ++E  EY+ LL +A    DPI     + AFA+S  +        + KPFNPLL ET+EL R +  F+ +SE++ H PPV AF  E   ++    + P   FWGKS+ +  +G + L+     E++ W      + N+I G+ ++E       ++ S    + + F   G F          I      +R  E  + GKWT++L                   N T                                    IW+      N    Y FT FT  LN+IT+     LPPTDSR R D+R  EEG +D+A   K  LE+ QR +R
Sbjct:  628 TRRNDIPEAAASPP--SLLSFLRKNVGKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDPITF---VSAFAISFLSIYRDKTRTLRKPFNPLLAETFELIREDMGFRLISEKVSHRPPVFAFFAEHLDWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFE-VHSSKGDKSHILFDKAGMFSGRSEGFKVSIIPPPSSNRKKE-TLAGKWTQSL------------------ANET--------------------------------THETIWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEGNVDKAEEWKLKLEQLQRERR 952          

Query:  305 GKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELH--RPNFK---YVSEQICHHPPVSAFHVESP--TFKFYGAIHPKLNFWGKSVVITPKGNITLELL--------PWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGW-FGK------NMHRVDGDIYYGQRKSRHVERKVYGKWTEALF-------SVSPEVWNDDSSTS 1012
            G +L++IT+P    E  S L+R+T  +++ E L QA +E DP+KR   +  + ++G       + KP NP+LGE +  +   PN +   Y+SEQ  HHPP  A+    P  + +  G + PK  F G S      G+  L+ L        P   V T  NV   V  ++ GK+ IE    M  I  S N  AD+ F + G+ FG        +   DG+ YY          ++ GKW + ++         SP+V+ D    S
Sbjct:   61 GCDLTRITLPTFILEKKSMLERVTNQLQFPEFLLQAHSEKDPLKRFLYVMKWYLAGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAYYISEQTSHHPPECAYFYMIPESSIRVDGVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGNGKPEKYVLTQPNVY--VRGILFGKMRIELGDHM--IIKSPNFQADIEFKTKGYVFGTYDAIEGTVKDYDGNAYY----------EISGKWNDVMYLKDLKQPRSSPKVFLDTHKES 311          

Query:  305 GKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELH--RPNFK---YVSEQICHHPPVSAFHVESP--TFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWN------EVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALF 970
            G +LS+IT+P    E  S L+R+T  +++ ++L +A +  D ++R  K+ A+ ++G       + KP NP+LGE +  +   PN +   Y++EQ  HHPP SA+    P    +  G + PK  F G S     +G   L+ L         E YT          ++ GK+ IE    M I+        D+ F + G+       ++G I     K  +   ++ GKW + ++
Sbjct:   61 GCDLSRITLPTFILEKKSMLERITNQLQFPDVLLEAHSNKDGLQRFVKVVAWYLAGWHIGPRAVKKPLNPILGEHFTAYWDLPNKQQAFYIAEQTSHHPPESAYFYMIPESNIRVDGVVVPKSKFLGNSSAAMMEGLTVLQFLDIKDANGKPEKYTLSQPNVYARGILFGKMRIELGDHMVIMGPKYQV--DIEFKTKGFISGTYDAIEGTIKDYDGKEYY---QISGKWNDIMY 290          

Query:  254 MPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPNFKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            M S+  FSVWT LKQCIGK+LS+ITMP++FNEP++FLQR+TEY+EYSELL  A ++ DP +R++                +GKPFNPLLGETYEL RP F+ V+EQ+ HHPP++A   ES  F F+  + PKL FWGK V + PKG +TL+    NEVYTW NV   VHN+I+G++WIE  G + I + S+   A + F   GWFGK +++V+  I+  Q K +    K  G WT+ +     E           HV         +  +  +    +   + ++P  +        W    RP +S   YNFTSF M LN++       LPPTDSR R D R +E G LD A   K  LEEKQRA R   + S                   +Q+  P WF E++NPYT +M+W ++G YW+RDW  CPDIF
Sbjct:    1 MLSRNEFSVWTVLKQCIGKDLSRITMPVIFNEPLTFLQRITEYMEYSELLHTAASQDDPTRRLQ----------------VGKPFNPLLGETYELVRPGFRLVAEQVSHHPPITALQCESDDFIFHVTVQPKLKFWGKGVEVQPKGMVTLKFPKHNEVYTWNNVNSCVHNIIVGQLWIEQYGQIEISSLSSGDRATIHFKPAGWFGKELNKVEATIHCAQDKKKRYTLK--GDWTDKITCYRSET----------HVTRKQSKRGKQDFEIASTSSSETSLELHSPVTL--------WTCSHRPPHSKEMYNFTSFAMQLNELLPRDKETLPPTDSRLRPDCRALENGDLDRATAEKIRLEEKQRAARRERQKS-------------------DQEWAPRWFKEEMNPYTGQMDWLYSGGYWDRDWQECPDIF 378          

Query:  221 IYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRP---NFKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHR-VDGDIYYGQRKSRHVERKVYGKW------TEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITD-IRNQKEGPVWFAEKLNPYTNKMEWQFTGEYW----NRDWSVCPDIF 1552
            + TYRT +P P P  ++ ++W+ LK CIGKEL+KI MP+ FNEP+S LQR+TE +EYSE+LD+A A T  +++M  + AF VS  ++   R  KPFNPLLGET+E  R     ++ ++EQ+ HHPP SAFH E   + F+        F GK + I P+G   L+ +     YTW+ V  TVHN+I+GK+WI+ SG M I NH+ N    L + +  +FG++  R V G +    +  R+V   + G W       + ++  SP V    SS+ K    +   +                                ++WK    P  +   Y  TSF + LN+  D     + PTDSRFR D R ME    +EA   K  +E++QR +R             +  ++  ++D I  +   P WF + ++  T+     + G YW     +DW  CPDIF
Sbjct:  323 LKTYRTSIP-PRPD-ISINLWSILKNCIGKELTKIPMPVNFNEPLSMLQRITEELEYSEVLDKAAACTSSLEQMCYVAAFTVSSYSTTSNRTNKPFNPLLGETFECDRSEDYGWRSLAEQVSHHPPASAFHAEHKDWIFWQEFSATSKFRGKYLQIIPQGIAHLKFIKSGNHYTWRKVTTTVHNIIVGKLWIDQSGEMDIANHTTNENCHLKYDAYNYFGRDTPRKVTGVVTDSTKTVRYV---ISGTWDNKIEAAKVVYLKSPGVKAQGSSSQKGQPQTLPPV--------------------------------VLWKRVLPPPENEKMYAMTSFAITLNEPED----HVAPTDSRFRPDQRLMENCHWEEANQEKLRIEDQQRTRR----------RKREQEAAEALSDGIFYEGYSPSWFEKIVDELTDMPMHVYKGGYWEAKEKKDWGSCPDIF 730          

Query:  176 YFDAEDENGQHGDNHIYT----YRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYEL--HRPNFKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEV-WNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYW 1519
            Y D E E  +  ++ I+T     RT LP         S+ +F+K  +GK+++K+TMP+ FNEP+SFLQRL+E +EY+++L++A    + + ++  + AFA S  A+   R  KPFNPLLGET+E   +   F  ++EQ+ HHPP+SA H ES  + F+        F G+   + P G+  L+       ++W+  V T+HN+++G ++++  G M + NH+      + F  V     N  ++ G++   + K R+V   + G W ++L  +  +  +NDDS                                              +W A  RPD+S   Y FT FT+ LN   D       PTD R R D+R +E G +D +A  K+ LEEKQRA R             +  +  E    R  K+   WF  K +PYT   ++ + G YW
Sbjct:   18 YGDQETEFNRLREHTIFTKRRPRRTALPATRERSSIRSLISFMKTVVGKDMTKVTMPVHFNEPVSFLQRLSEDLEYADILNRACVCKNNLVKLAHVAAFASSTYATVLSRFWKPFNPLLGETFEYIDNDNGFALIAEQVSHHPPISALHAESSHWVFWQEYKLDTKFRGQFFKVIPTGHCHLKFKTNGHHFSWKKPVTTIHNILVGSLYVDQEGDMVVTNHTTKETCTVHFMPVRKVQDNFKKLKGEVKDPEGKVRYV---IEGSWDKSLECIPQDTGFNDDSID--------------------------------------------LWTAVARPDDSYKMYAFTRFTIQLN---DPDYGVTCPTDCRNRPDIRQLELGKIDSSAAEKHRLEEKQRASR------------RERDTKGEAWTPRYDKKDR-WFVPKEDPYTRTFDYVYRGGYW 409          

Query: 1184 YNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            YNFTSF M LN++       LPPTDSR R D R +E G LD A   K  LEEKQRA R   + S                   +Q+  P WF E++NPYT +M+W ++G YW+RDW  CPDIF
Sbjct:    2 YNFTSFAMQLNELLPRDKETLPPTDSRLRPDCRALENGDLDRATAEKIRLEEKQRAARRERQKS-------------------DQEWAPRWFKEEMNPYTGQMDWLYSGGYWDRDWQECPDIF 105          

Query:  278 VWTFLKQCI-GKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELH--RPNFK---YVSEQICHHPPVSAFHVES--PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHR--VDGDIYYGQRKSRHVERKVYGKW 955
            +W  LKQ   G +LS++T+P    EP SFL +L+++  ++++L +A  E +P  RM+++  + +SG       + KP+NP++GE +  +   P      +VSEQ+ HHPPVSAF+V +    F   GAI  K  F+G S      G  TL LL + E YT          ++IG + +E  G + I        A++ F    ++ K+     + G I  G+     +E    GKW
Sbjct:  244 LWALLKQVKPGMDLSRVTLPTFILEPRSFLDKLSDFYYHTDILSRAACEENPYSRMKEVIRWYLSGFYKKPKGLKKPYNPIIGEMFRCYWQHPQGSRTFFVSEQVSHHPPVSAFYVSNRQDGFVINGAILAKSKFYGNSSSAILDGAATLALLRFGEEYTMTMPYAHCKGILIGTLTMELGGTVTINCEKTGYKAEIEFKLKPFWKKSGESNYIAGKIIMGKETLCKIE----GKW 475          

Query:  236 TGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVES--PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            T LP PM S+ + S+W+ LK+CIG ELSKITMP+VFNEP+SFLQRLTEY+E++ L+ QA A TD ++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F++VSEQ+ HHPP+SAFH E     F F+G+I+PKL FWGKS+   PKG ITLEL  +NE YTW N  C VHN+I+G++WIE  G + ++NH      +L F   G FGK +H+V+G   Y   KS+     +YGKWTE L+ V P +++ +    K++       E     +N+ ++  + +P         +    LIWK  PRP+NSA FY F++F M LN++       LPPTDSR R D+R ME G +D A+  K  LEEKQR  R               S S E   IR       WF +  NP+    +W +   YW+R+++  PDI+
Sbjct:   20 TSLPAPMFSRNDVSIWSILKKCIGMELSKITMPVVFNEPLSFLQRLTEYMEHTYLIHQANAATDSLERMKCVAAFAVSAVASQWERTGKPFNPLLGETYELIRDDLGFRWVSEQVSHHPPISAFHAEGFQEDFVFHGSIYPKLKFWGKSIEAEPKGTITLELPKYNEAYTWTNPTCCVHNIIVGQLWIEQYGNVEVVNHKTGERCNLMFKRCGLFGKELHKVEG---YILDKSKKKLCAIYGKWTECLYVVDPAIYDANKKMDKKNSE-----EKKSNKENSVDEEAEEMPPPVAETVQVIPGSELIWKITPRPENSAKFYAFSTFAMQLNELDKIMEGVLPPTDSRLRPDIRAMENGDMDLASGEKKRLEEKQRTAR------------KNRSKSTEEWKIR-------WFQQGTNPHNKAQDWIYLKGYWDRNYTQMPDIY 435          

Query:  179 FDAEDENGQHGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVES--PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            FD +   G   +N ++  R  LP  M S+ NFS+W+ LK+CIG ELSKI MP+ FNEP+SFLQR++EY+E++ L+ +A + +D + RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  ++++SEQ+ HHPPVSAFH +S    F+F+G+I+PKL FWGKSV   PKG + L+LL   EVYTW N +C VHN+I+GK+WIE  G + IINHS      L F   G FGK++H+V+G   Y Q KS+   R +YGKWTE ++SV P+ ++      KR      +++ +   +    D    + +  T     +    L+W+  PRP +SA  YNFTSF + LN++     + L PTD R R D+R ME G ++ A+  K  LEEKQRA R          +                     WF   +NP+T   +W +TG Y++R++S CP+I+
Sbjct:   30 FDRKQVTGSRQENGMWERRKTLPAQMISRSNFSIWSILKKCIGMELSKIAMPVEFNEPLSFLQRISEYMEHTHLIHKACSLSDSVDRMQVVAAFAVSAVASQWERTGKPFNPLLGETYELIREDEGYRWISEQVSHHPPVSAFHAQSLKQEFEFHGSIYPKLKFWGKSVEAEPKGTMVLDLLKHKEVYTWTNPMCCVHNIILGKLWIEQYGSVEIINHSTGDKCVLNFKPCGMFGKDLHKVEG---YIQDKSKKKRRVIYGKWTECIYSVDPKSYD----AYKRAAGDPKRLKQENSCEGEEADEMPDVQETVTV----IPGSALLWRITPRPAHSAQIYNFTSFAVTLNELEPGMEKLLAPTDCRLRPDIRAMENGDMELASAEKERLEEKQRAARRERSEEEETWSTR-------------------WFQLGVNPHTGAEDWFYTGGYFDRNYSDCPNIY 461          

Query:  215 NHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRP--NFKYVSEQICHHPPVSAFHVE--SPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            N I  +RT LP PM S+   SVW+ LK+CIG ELSKITMPI FNEP+SFLQR+TEY+E++ L+++A + +D I+RM+ + AFAVS  AS W R GKPFNPLLGETYEL R    F+ +SEQ+ HHPPVSAFH E  +  F F+G+I+PKL FWGKSV   PKG ITLE++   E YTW N  C VHN+I+GK+WIE  G + I+NH       L F   G FGK +H+V+G   Y Q K++     +YGKWTE ++SV P+ +     + K+        E     ++  +++ +     +      +    L+W+   RP +S+  YNFT+F M LN++       L PTD RFR D+R ME G +DEA+  K  LEEKQRA R                         ++     WF    NP+T   +W + G+Y+NR++   PDI+
Sbjct:   48 NGIKKHRTSLPAPMFSRNTVSVWSILKKCIGLELSKITMPIAFNEPLSFLQRMTEYMEHTYLINKACSLSDSIERMQAVAAFAVSAVASQWDRTGKPFNPLLGETYELVREEQGFRLISEQVSHHPPVSAFHAEGLAGDFAFHGSIYPKLKFWGKSVEAEPKGTITLEIIKHKEAYTWSNPYCCVHNIILGKLWIEQYGNVEIVNHRTGDKCVLNFKPCGMFGKELHKVEG---YIQDKNKKKHCVIYGKWTECMWSVDPQAYEAHKKSEKKGDKKQKNEELRRSENDEADNMPEVQETVSV-----VPGSTLLWRIDSRPAHSSRMYNFTTFAMSLNELEPGMEAMLAPTDCRFRPDIRAMENGNIDEASKEKERLEEKQRAARKERAK-------------------NDEDWSTRWFHLSTNPHTGNQDWIYNGDYFNRNYKDLPDIY 470          

Query:  206 HGD------NHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVES--PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            HGD      N I  +R  LP PM S+ +FS+W+ L+ CIG ELSKITMP++FNEP+SFLQRLTEY+E++ L+ QA A +D ++RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  F+ +SEQ+ HHPPVSAFH E     F F+G+I+PKL FWGKSV   PKG ITLEL  +NE YTW N  C VHN+I+G++WIE  G + +INH       L F   G FGK +H+V+G I+    KS+     +YGKWTE L  V+   +       K+        +    GD  +         +  P        +L+W+  PRP NS   Y+FT F M LN++T      +P TD R R D+R ME G +D A+  K  LEEKQRA R               S S E    R+   GP WF +  NP+T   +W F+G YW+R +   PDI+
Sbjct:  449 HGDKNETQPNGITKHRMSLPAPMFSRNDFSIWSILRNCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHQANASSDSVERMKCVAAFAVSAVASQWERTGKPFNPLLGETYELVREDLGFRLISEQVSHHPPVSAFHAEGLKQDFVFHGSIYPKLKFWGKSVEAEPKGTITLELPKYNEAYTWTNPTCCVHNIIVGQLWIEQYGNVEVINHRTGEKCCLNFKPCGLFGKELHKVEGHIF---DKSKKKLCALYGKWTECLHVVNTAAFEAHKKNDKKSSEDKKSSKAGSSGDQEDVPSPAADTVEVIP------GSQLLWRIAPRPTNSTQMYSFTCFAMQLNELTPEMEGVIPQTDCRLRPDIRAMENGNIDLASEEKKRLEEKQRAAR------------KNRSKSEEDWKSRSPALGPRWFQQGQNPHTRSQDWLFSGGYWDRTYPNLPDIY 886          

Query:  242 LPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVES--PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            LP  M S+ NFS+W+ LK+CIG ELSKI MP+ FNEP+SFLQR++EY+E++ L+ +A + +D + RM+ + AFAVS  AS W R GKPFNPLLGETYEL R +  ++++SEQ+ HHPPVSAFH +S    F+F+G+I+PKL FWGKSV   PKG + L+LL   EVYTW N +C VHN+I+GK+WIE  G + IINHS      L F   G FGK++H+V+G   Y Q KS+   R +YGKWTE ++SV P+ ++      KR      +++ +       +++ D            +    L+W+  PRP +SA  YNFTSF + LN++     + L PTD R R D+R ME G ++ A+  K  LEEKQRA R          +                     WF   +NP+T   +W +TG Y++R++S CP+I+
Sbjct:   29 LPAQMISRSNFSIWSILKKCIGMELSKIAMPVEFNEPLSFLQRISEYMEHTHLIHKACSLSDSVDRMQVVAAFAVSAVASQWERTGKPFNPLLGETYELIREDEGYRWISEQVSHHPPVSAFHAQSLKQEFEFHGSIYPKLKFWGKSVEAEPKGTMVLDLLKHKEVYTWTNPMCCVHNIILGKLWIEQYGSVEIINHSTGDKCVLNFKPCGMFGKDLHKVEG---YIQDKSKKKRRVIYGKWTECIYSVDPKSYD----AYKRAAGDPKRLKQNSCEGEEADEMPDVQETVTV-----IPGSALLWRITPRPAHSAQIYNFTSFAVTLNELEPGMEKLLAPTDCRLRPDIRAMENGDMELASAEKERLEEKQRAARRERSEEEETWSTR-------------------WFQLGVNPHTGAEDWFYTGGYFDRNYSDCPNIY 438          

Query:  161 TDPEEYFDAEDENGQHGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPNFKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            TDPEEYFDAEDENGQHGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAE DPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPNFKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIENDEKGDNNNNDIDDPLPQDNTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALKSSNSKKNMNKSSSSHEITDIRNQKEGPVWFAEKLN YTNKMEWQFTGEYWNRDWSVCPDIF
Sbjct:    4 TDPEEYFDAEDENGQHGDNHIYTYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAEIDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPNFKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIENDEKGDNNNNDIDDPLPQDNTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALKSSNSKKNMNKSSSSHEITDIRNQKEGPVWFAEKLNSYTNKMEWQFTGEYWNRDWSVCPDIF 467          

Query:  224 YTYRTGLPKPMPSKLNFS-VWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRP---NFKYVSEQICHHPPVSAFHVES-PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWF--GKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWN------------DDSS---------------TSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTP--------------CDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            Y +R  LP PM  K   S +W+ +K   GK+LSK TMPI  NEPISFLQR++EY+EYS LL QA  E DPI R+E I  F +S  +S + R GKPFNPLLGET+EL+R     + +VSEQ+ HHPP+SAF+VE+ P F+F+G+++PKL FWGKS+ I PKGN+ + LL  NEVYTW+NV   ++N++IGK+ I H G   I   + N  A L + S GWF  G++  R   + +   + S  V + +YG+W E LFSVS + W              DSS               +S  H+     +E  +    N+N       +   P               D+ L +Q  +WK  PRP +S ++Y+FT FTM LN++   +  ELPP+DSR R D+R +E G +D+A+  K+ LE KQR  R   K                 T   +Q+   +WF  K + Y+N  EW F G+Y+ R+W +CPDIF
Sbjct:   22 YCHRKFLPCPMTKKTEESNLWSLVKSNTGKDLSKTTMPINLNEPISFLQRISEYMEYSNLLFQASLENDPINRLELITTFVISDVSSTYKRSGKPFNPLLGETFELNRKEERGYIFVSEQVSHHPPISAFYVEAEPYFRFWGSLYPKLQFWGKSLEIYPKGNLYIHLLDINEVYTWENVPSVINNLLIGKVNICHQGENTIKCLTTNTKAVLKWKSDGWFKIGEDCSRNRLEAHLYNKHSEKV-KVIYGRWNEVLFSVSADDWKLRNEKKLWRTPLTDSSVTGVVSKLGNLRFFPSSSFHIMQPSSLEVPDSSPGNHNCTSPIDCKKINPGSSSCASSPTSSEEIDLHLPHQNFLWKVSPRPPHSRLYYDFTYFTMILNEVPRDYYSELPPSDSRKRPDIRLLENGNIDDASKEKSRLENKQRQTRKQFK-----------------TKKCSQECQALWFDLKESEYSNIPEWVFNGKYFQRNWEICPDIF 494          

Query:  275 SVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRP---NFKYVSEQICHHPPVSAFHVES-PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWF--GKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWN------------DDSS---------------TSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTP--------------CDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKEGPVWFAEKLNPYTNKMEWQFTGEYWNRDWSVCPDIF 1552
            ++W+ +K   GK+LSK TMPI  NEPISFLQR++EY+EYS LL QA  E DPI R+E I  F +S  +S + R GKPFNPLLGET+EL+R     + +VSEQ+ HHPP+SAF+VE+ P F+F+G+++PKL FWGKS+ I PKGN+ + LL  NEVYTW+NV   ++N++IGK+ I H G   I   + N  A L + S GWF  G++  R   + +   + S  V + +YG+W E LFSVS + W              DSS               +S  H+     +E  +    N+N       +   P               D+ L +Q  +WK  PRP +S ++Y+FT FTM LN++   +  ELPP+DSR R D+R +E G +D+A+  K+ LE KQR  R   K                 T   +Q+   +WF  K + Y+N  EW F G+Y+ R+W +CPDIF
Sbjct:    9 NLWSLVKSNTGKDLSKTTMPINLNEPISFLQRISEYMEYSNLLFQASLENDPINRLELITTFVISDVSSTYKRSGKPFNPLLGETFELNRKEERGYIFVSEQVSHHPPISAFYVEAEPYFRFWGSLYPKLQFWGKSLEIYPKGNLYIHLLDINEVYTWENVPSVINNLLIGKVNICHQGENTIKCLTTNTKAVLKWKSDGWFKIGEDCSRNRLEAHLYNKHSEKV-KVIYGRWNEVLFSVSADDWKLRNEKKLWRTPLTDSSVTGVVSKLGNLRFFPSSSFHIMQPSSLEVPDSSPGNHNCTSPIDCKKINPGSSSCASSPTSSEEIDLHLPHQNFLWKVSPRPPHSRLYYDFTYFTMILNEVPRDYYSELPPSDSRKRPDIRLLENGNIDDASKEKSRLENKQRQTRKQFK-----------------TKKCSQECQALWFDLKESEYSNIPEWVFNGKYFQRNWEICPDIF 463          

Query:  224 YTYRTGLPKPMPSKLNFS-VWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRP---NFKYVSEQICHHPPVSAFHVES-PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWF--GKNMHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWN------------DDSS---------------TSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTP--------------CDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEG 1297
            Y +R  LP PM  K   S +W+ +K   GK+LSK TMPI  NEPISFLQR++EY+EYS LL QA  E DPI R+E I  F +S  +S + R GKPFNPLLGET+EL+R     + +VSEQ+ HHPP+SAF+VE+ P F+F+G+++PKL FWGKS+ I PKGN+ + LL  NEVYTW+NV   ++N++IGK+ I H G   I   + N  A L + S GWF  G++  R   + +   + S  V + +YG+W E LFSVS + W              DSS               +S  H+     +E  +    N+N       +   P               D+ L +Q  +WK  PRP +S ++Y+FT FTM LN++   +  ELPP+DSR R D+R +E G
Sbjct:   22 YCHRKFLPCPMTKKTEESNLWSLVKSNTGKDLSKTTMPINLNEPISFLQRISEYMEYSNLLFQASLENDPINRLELITTFVISDVSSTYKRSGKPFNPLLGETFELNRKEERGYIFVSEQVSHHPPISAFYVEAEPYFRFWGSLYPKLQFWGKSLEIYPKGNLYIHLLDINEVYTWENVPSVINNLLIGKVNICHQGENTIKCLTTNTKAVLKWKSDGWFKIGEDCSRNRLEAHLYNKHSEKV-KVIYGRWNEVLFSVSADDWKLRNEKKLWRTPLTDSSVTGVVSKLGNLRFFPSSSFHIMQPSSLEVPDSSPGNHNCTSPIDCKKINPGSSSCASSPTSSEEIDLHLPHQNFLWKVSPRPPHSRLYYDFTYFTMILNEVPRDYYSELPPSDSRKRPDIRLLENG 426          

Query:  227 TYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAETDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN---FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNM-HRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIEXXXXXXXXXXXXXXXXXXXXTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALXXXXXXXXXXXXXXXHEITDIRNQKE-----GPVWFAEKLNPYTNKMEWQFTGEYW----NRDWSVCPDIF 1552
            T RT +P P P+ +N ++W+ +K CIGK+LSKI MP+ F+EPIS LQRL E  EYS +LD+A +  +PI+++  + AF VS  A+   RI KPFNPLLGETYEL R +   ++  +EQ+CHHPP  A H ES  +  +        F GK + I P G   L        Y W+ +  T+HN+I+G++WI++ G M IIN +      L++     F  +   RV G I     K  +V   + G W E L              +K  +++T+ ++         + I                   L+W+  P P N   +Y F+SF + LN+I +    ++ PTDSR R D + MEEG  DEA   K  LEE+QR++RV                  EI  +   KE      P+WF    +P      ++F G+YW     +DWS+C  IF
Sbjct:  419 TRRTQIP-PKPN-INMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAI---TDKLNNVCCVLNGTWDEKL-------------EAKNVISNTETVQGRTYLATEESSI-------------------LLWQRYPLPPNFDKYYYFSSFAITLNEIEE----DIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRV------------------EILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 814