SMED30002579

Overview
NameSMED30002579
Smed IDSMED30002579
Length (bp)1071
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30002579 (SMED30002579) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30002579 (SMED30002579) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30002579 (SMED30002579) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30002579 (SMED30002579) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30002579

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30002579h1SMcG0016104 Contig4890GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30002579h1SMcG0016104 Contig4890GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
epidermisSMED30002579h1SMcG0016104 dd_Smed_v4_8886_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30002579h1SMcG0016104 dd_Smed_v4_8886_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30002579h1SMcG0016104 Contig4890GPL15192PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
epidermisSMED30002579h1SMcG0016104 dd_Smed_v4_8886_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30002579 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.000551:54286..59838 -5259
Homology
BLAST of SMED30002579 vs. Ensembl Human
Match: ELF5 (E74 like ETS transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:3320])

HSP 1 Score: 50.447 bits (119), Expect = 7.034e-7
Identity = 32/116 (27.59%), Postives = 59/116 (50.86%), Query Frame = 3
Query:  591 EYLQSNCKSDSRVANVRPRDAPRNQI---GMLTFILDLLNHPYFEPC--IKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            +Y  SNC   S + +       R  +    +  F+ DLL  P  E C  ++WED++   F+++ S+ +A  W   K+ND  ++E  +R +RY    G  +++D  ++  Y+F K +
Sbjct:   67 DYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVRDLLLSPE-ENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVD--RRLVYKFGKNA 179          
BLAST of SMED30002579 vs. Ensembl Human
Match: ELF3 (E74 like ETS transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3318])

HSP 1 Score: 51.6026 bits (122), Expect = 1.251e-6
Identity = 30/96 (31.25%), Postives = 50/96 (52.08%), Query Frame = 3
Query:  639 RPRDAPRNQIGMLTFILDLLNHPYF-EPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            + + APR    +  FI D+L HP   E  +KWE++    FK + S+ VA  W   K+N   ++E  +R +RY       +++D ++   Y+F K S
Sbjct:  265 KSKHAPRG-THLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRR-LVYKFGKNS 358          
BLAST of SMED30002579 vs. Ensembl Human
Match: ELF3 (E74 like ETS transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3318])

HSP 1 Score: 51.6026 bits (122), Expect = 1.251e-6
Identity = 30/96 (31.25%), Postives = 50/96 (52.08%), Query Frame = 3
Query:  639 RPRDAPRNQIGMLTFILDLLNHPYF-EPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            + + APR    +  FI D+L HP   E  +KWE++    FK + S+ VA  W   K+N   ++E  +R +RY       +++D ++   Y+F K S
Sbjct:  265 KSKHAPRG-THLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRR-LVYKFGKNS 358          
BLAST of SMED30002579 vs. Ensembl Human
Match: ELF3 (E74 like ETS transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3318])

HSP 1 Score: 51.6026 bits (122), Expect = 1.251e-6
Identity = 30/96 (31.25%), Postives = 50/96 (52.08%), Query Frame = 3
Query:  639 RPRDAPRNQIGMLTFILDLLNHPYF-EPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            + + APR    +  FI D+L HP   E  +KWE++    FK + S+ VA  W   K+N   ++E  +R +RY       +++D ++   Y+F K S
Sbjct:  265 KSKHAPRG-THLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRR-LVYKFGKNS 358          
BLAST of SMED30002579 vs. Ensembl Human
Match: ELF5 (E74 like ETS transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:3320])

HSP 1 Score: 50.447 bits (119), Expect = 1.494e-6
Identity = 32/116 (27.59%), Postives = 59/116 (50.86%), Query Frame = 3
Query:  591 EYLQSNCKSDSRVANVRPRDAPRNQI---GMLTFILDLLNHPYFEPC--IKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            +Y  SNC   S + +       R  +    +  F+ DLL  P  E C  ++WED++   F+++ S+ +A  W   K+ND  ++E  +R +RY    G  +++D  ++  Y+F K +
Sbjct:  135 DYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVRDLLLSPE-ENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVD--RRLVYKFGKNA 247          
BLAST of SMED30002579 vs. Ensembl Celegans
Match: ets-4 (Transcription factor ets-4 [Source:UniProtKB/Swiss-Prot;Acc:A8WFJ9])

HSP 1 Score: 47.3654 bits (111), Expect = 8.736e-6
Identity = 24/83 (28.92%), Postives = 45/83 (54.22%), Query Frame = 3
Query:  666 IGMLTFILDLLNHP-YFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQF 911
            + +  FI +LL+ P  +  C++W D+   TFKI +S L+A YW   K     +++  +R +R     G  ++ + K++  Y+F
Sbjct:  288 VHLWQFIRELLDQPKQYSACVRWVDRDEGTFKIESSLLLARYWGQRKNRSQMNYDKLSRSLRQYYKKGIIQKPEKKQRLVYKF 370          
BLAST of SMED30002579 vs. Ensembl Celegans
Match: ets-4 (Transcription factor ets-4 [Source:UniProtKB/Swiss-Prot;Acc:A8WFJ9])

HSP 1 Score: 47.3654 bits (111), Expect = 8.736e-6
Identity = 24/83 (28.92%), Postives = 45/83 (54.22%), Query Frame = 3
Query:  666 IGMLTFILDLLNHP-YFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQF 911
            + +  FI +LL+ P  +  C++W D+   TFKI +S L+A YW   K     +++  +R +R     G  ++ + K++  Y+F
Sbjct:  288 VHLWQFIRELLDQPKQYSACVRWVDRDEGTFKIESSLLLARYWGQRKNRSQMNYDKLSRSLRQYYKKGIIQKPEKKQRLVYKF 370          
BLAST of SMED30002579 vs. Ensembl Celegans
Match: ets-4 (Transcription factor ets-4 [Source:UniProtKB/Swiss-Prot;Acc:A8WFJ9])

HSP 1 Score: 47.3654 bits (111), Expect = 8.736e-6
Identity = 24/83 (28.92%), Postives = 45/83 (54.22%), Query Frame = 3
Query:  666 IGMLTFILDLLNHP-YFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQF 911
            + +  FI +LL+ P  +  C++W D+   TFKI +S L+A YW   K     +++  +R +R     G  ++ + K++  Y+F
Sbjct:  288 VHLWQFIRELLDQPKQYSACVRWVDRDEGTFKIESSLLLARYWGQRKNRSQMNYDKLSRSLRQYYKKGIIQKPEKKQRLVYKF 370          
BLAST of SMED30002579 vs. Ensembl Zebrafish
Match: elf3 (E74-like factor 3 (ets domain transcription factor, epithelial-specific ) [Source:ZFIN;Acc:ZDB-GENE-030131-8760])

HSP 1 Score: 53.1434 bits (126), Expect = 1.956e-7
Identity = 31/104 (29.81%), Postives = 55/104 (52.88%), Query Frame = 3
Query:  618 DSRVANVRPRDAPRNQIGMLTFILDLLNHP-YFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKSI 926
            D  + + + + APR    +  FI D+L HP   +  +KWED++   FK + S+ VA  W   K+N + ++E  +R +RY       +++D ++   Y+F K S 
Sbjct:  265 DHFIQSKKSKHAPRG-THLWEFIRDILIHPEQNQGLMKWEDRRDGVFKFLKSEAVAQLWGQKKKNSSMTYEKLSRAMRYYYKREILERVDGRR-LVYKFGKNST 366          
BLAST of SMED30002579 vs. Ensembl Zebrafish
Match: elf3 (E74-like factor 3 (ets domain transcription factor, epithelial-specific ) [Source:ZFIN;Acc:ZDB-GENE-030131-8760])

HSP 1 Score: 53.1434 bits (126), Expect = 2.364e-7
Identity = 31/104 (29.81%), Postives = 55/104 (52.88%), Query Frame = 3
Query:  618 DSRVANVRPRDAPRNQIGMLTFILDLLNHP-YFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKSI 926
            D  + + + + APR    +  FI D+L HP   +  +KWED++   FK + S+ VA  W   K+N + ++E  +R +RY       +++D ++   Y+F K S 
Sbjct:  307 DHFIQSKKSKHAPRG-THLWEFIRDILIHPEQNQGLMKWEDRRDGVFKFLKSEAVAQLWGQKKKNSSMTYEKLSRAMRYYYKREILERVDGRR-LVYKFGKNST 408          
BLAST of SMED30002579 vs. Ensembl Xenopus
Match: ENSXETT00000020719.1 (E74 like ETS transcription factor 3 [Source:NCBI gene;Acc:100144720])

HSP 1 Score: 50.0618 bits (118), Expect = 3.533e-6
Identity = 26/82 (31.71%), Postives = 45/82 (54.88%), Query Frame = 3
Query:  681 FILDLLNHPYF-EPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            FI D+L HP   +  +KWED+    FK + S+ VA  W   K+N + ++E  +R +RY       +++D ++   Y+F K +
Sbjct:  287 FIRDILLHPDLNQGLLKWEDRSEGVFKFLRSEAVAQLWGQKKKNSSMTYEKLSRAMRYYYKREILERVDGRRL-VYKFGKNA 367          
BLAST of SMED30002579 vs. Ensembl Mouse
Match: Elf3 (E74-like factor 3 [Source:MGI Symbol;Acc:MGI:1101781])

HSP 1 Score: 51.6026 bits (122), Expect = 8.368e-7
Identity = 30/94 (31.91%), Postives = 49/94 (52.13%), Query Frame = 3
Query:  645 RDAPRNQIGMLTFILDLLNHPYF-EPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            + APR    +  FI D+L HP   E  +KWE++    FK + S+ VA  W   K+N   ++E  +R +RY       +++D ++   Y+F K S
Sbjct:  287 KHAPRG-THLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRL-VYKFGKNS 378          
BLAST of SMED30002579 vs. Ensembl Mouse
Match: Elf3 (E74-like factor 3 [Source:MGI Symbol;Acc:MGI:1101781])

HSP 1 Score: 51.6026 bits (122), Expect = 8.438e-7
Identity = 30/94 (31.91%), Postives = 49/94 (52.13%), Query Frame = 3
Query:  645 RDAPRNQIGMLTFILDLLNHPYF-EPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            + APR    +  FI D+L HP   E  +KWE++    FK + S+ VA  W   K+N   ++E  +R +RY       +++D ++   Y+F K S
Sbjct:  267 KHAPRG-THLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRL-VYKFGKNS 358          
BLAST of SMED30002579 vs. UniProt/SwissProt
Match: sp|Q3UPW2|ELF3_MOUSE (ETS-related transcription factor Elf-3 OS=Mus musculus OX=10090 GN=Elf3 PE=1 SV=1)

HSP 1 Score: 51.6026 bits (122), Expect = 5.853e-6
Identity = 30/94 (31.91%), Postives = 49/94 (52.13%), Query Frame = 3
Query:  645 RDAPRNQIGMLTFILDLLNHPYF-EPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            + APR    +  FI D+L HP   E  +KWE++    FK + S+ VA  W   K+N   ++E  +R +RY       +++D ++   Y+F K S
Sbjct:  287 KHAPRG-THLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRL-VYKFGKNS 378          
BLAST of SMED30002579 vs. UniProt/SwissProt
Match: sp|P78545|ELF3_HUMAN (ETS-related transcription factor Elf-3 OS=Homo sapiens OX=9606 GN=ELF3 PE=1 SV=1)

HSP 1 Score: 51.6026 bits (122), Expect = 6.009e-6
Identity = 30/96 (31.25%), Postives = 50/96 (52.08%), Query Frame = 3
Query:  639 RPRDAPRNQIGMLTFILDLLNHPYF-EPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            + + APR    +  FI D+L HP   E  +KWE++    FK + S+ VA  W   K+N   ++E  +R +RY       +++D ++   Y+F K S
Sbjct:  265 KSKHAPRG-THLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRR-LVYKFGKNS 358          
BLAST of SMED30002579 vs. UniProt/SwissProt
Match: sp|Q4V7E1|ELF3_RAT (ETS-related transcription factor Elf-3 OS=Rattus norvegicus OX=10116 GN=Elf3 PE=2 SV=1)

HSP 1 Score: 51.2174 bits (121), Expect = 7.375e-6
Identity = 30/94 (31.91%), Postives = 49/94 (52.13%), Query Frame = 3
Query:  645 RDAPRNQIGMLTFILDLLNHPYF-EPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            + APR    +  FI D+L HP   E  +KWE++    FK + S+ VA  W   K+N   ++E  +R +RY       +++D ++   Y+F K S
Sbjct:  291 KHAPRG-THLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRR-LVYKFGKNS 382          
BLAST of SMED30002579 vs. UniProt/SwissProt
Match: sp|Q9UKW6|ELF5_HUMAN (ETS-related transcription factor Elf-5 OS=Homo sapiens OX=9606 GN=ELF5 PE=1 SV=2)

HSP 1 Score: 50.447 bits (119), Expect = 8.796e-6
Identity = 32/116 (27.59%), Postives = 59/116 (50.86%), Query Frame = 3
Query:  591 EYLQSNCKSDSRVANVRPRDAPRNQI---GMLTFILDLLNHPYFEPC--IKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            +Y  SNC   S + +       R  +    +  F+ DLL  P  E C  ++WED++   F+++ S+ +A  W   K+ND  ++E  +R +RY    G  +++D  ++  Y+F K +
Sbjct:  145 DYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVRDLLLSPE-ENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVD--RRLVYKFGKNA 257          
BLAST of SMED30002579 vs. TrEMBL
Match: A0A1I8GPB9 (ETS domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 68.5514 bits (166), Expect = 3.759e-9
Identity = 32/83 (38.55%), Postives = 55/83 (66.27%), Query Frame = 3
Query:  681 FILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWG-YFKQIDMKKQRTYQFNKKSI 926
            F+L LLN+P     I+W D+++  FK+++   VA  W  +K N T ++E FARGIR+ R  G YF+  + +K++ Y+F++K++
Sbjct:  240 FLLKLLNNPSCSSLIRWLDRENRLFKVLHPVTVARLWQFIKGNRTDNYECFARGIRHSRDIGKYFEAHEFRKKKVYKFSEKAL 322          
BLAST of SMED30002579 vs. TrEMBL
Match: A0A267F0N9 (ETS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006668g2 PE=3 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 3.967e-9
Identity = 32/83 (38.55%), Postives = 55/83 (66.27%), Query Frame = 3
Query:  681 FILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWG-YFKQIDMKKQRTYQFNKKSI 926
            F+L LLN+P     I+W D+++  FK+++   VA  W  +K N T ++E FARGIR+ R  G YF+  + +K++ Y+F++K++
Sbjct:  240 FLLKLLNNPSCSSLIRWLDRENRLFKVLHPVTVARLWQFIKGNRTDNYECFARGIRHSRDIGKYFEAHEFRKKKVYKFSEKAL 322          
BLAST of SMED30002579 vs. TrEMBL
Match: A0A267GQD5 (ETS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006668g3 PE=3 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 4.113e-9
Identity = 32/83 (38.55%), Postives = 55/83 (66.27%), Query Frame = 3
Query:  681 FILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWG-YFKQIDMKKQRTYQFNKKSI 926
            F+L LLN+P     I+W D+++  FK+++   VA  W  +K N T ++E FARGIR+ R  G YF+  + +K++ Y+F++K++
Sbjct:  240 FLLKLLNNPSCSSLIRWLDRENRLFKVLHPVTVARLWQFIKGNRTDNYECFARGIRHSRDIGKYFEAHEFRKKKVYKFSEKAL 322          
BLAST of SMED30002579 vs. TrEMBL
Match: A0A1I8FYC8 (ETS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006668g1 PE=3 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 4.162e-9
Identity = 32/83 (38.55%), Postives = 55/83 (66.27%), Query Frame = 3
Query:  681 FILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWG-YFKQIDMKKQRTYQFNKKSI 926
            F+L LLN+P     I+W D+++  FK+++   VA  W  +K N T ++E FARGIR+ R  G YF+  + +K++ Y+F++K++
Sbjct:  241 FLLKLLNNPSCSSLIRWLDRENRLFKVLHPVTVARLWQFIKGNRTDNYECFARGIRHSRDIGKYFEAHEFRKKKVYKFSEKAL 323          
BLAST of SMED30002579 vs. TrEMBL
Match: A0A267FLW3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005521g2 PE=3 SV=1)

HSP 1 Score: 63.5438 bits (153), Expect = 4.398e-7
Identity = 31/86 (36.05%), Postives = 52/86 (60.47%), Query Frame = 3
Query:  681 FILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWG-YFKQIDMKKQRTYQFNKKSIQTY 935
            F+L LL++      I+W DK +  FK++    +A  W  +K N T ++E FARGIR+ R  G YF+    ++++ Y+F+ K+I+ Y
Sbjct:  606 FLLKLLDNSRCRANIEWVDKYNRLFKVVTPSAIAKLWKHIKGNKTDNYECFARGIRHSRDIGRYFEPHGFRQKKIYKFSPKAIEDY 691          
BLAST of SMED30002579 vs. Ensembl Cavefish
Match: elf3 (E74 like ETS transcription factor 3 [Source:NCBI gene;Acc:103047838])

HSP 1 Score: 50.447 bits (119), Expect = 1.291e-6
Identity = 31/104 (29.81%), Postives = 55/104 (52.88%), Query Frame = 3
Query:  615 SDSRVANVRPRDAPRNQIGMLTFILDLLNHPYF-EPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            S+  V   + + +PR    +  FI D+L HP   +  +KWED++   FK + S+ VA  W   K+N + ++E  +R +RY       +++D ++   Y+F K S
Sbjct:  255 SEHFVETKKNKHSPRG-THLWEFIRDILIHPEKNQGLMKWEDRRDGIFKFLKSEAVAQLWGQKKKNSSMTYEKLSRAMRYYYKREILERVDGRR-LVYKFGKNS 356          
BLAST of SMED30002579 vs. Ensembl Cavefish
Match: elf3 (E74 like ETS transcription factor 3 [Source:NCBI gene;Acc:103047838])

HSP 1 Score: 50.447 bits (119), Expect = 1.317e-6
Identity = 31/104 (29.81%), Postives = 55/104 (52.88%), Query Frame = 3
Query:  615 SDSRVANVRPRDAPRNQIGMLTFILDLLNHPYF-EPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            S+  V   + + +PR    +  FI D+L HP   +  +KWED++   FK + S+ VA  W   K+N + ++E  +R +RY       +++D ++   Y+F K S
Sbjct:  256 SEHFVETKKNKHSPRG-THLWEFIRDILIHPEKNQGLMKWEDRRDGIFKFLKSEAVAQLWGQKKKNSSMTYEKLSRAMRYYYKREILERVDGRR-LVYKFGKNS 357          
BLAST of SMED30002579 vs. Ensembl Sea Lamprey
Match: ehf (ets homologous factor [Source:ZFIN;Acc:ZDB-GENE-060312-7])

HSP 1 Score: 46.9802 bits (110), Expect = 2.575e-7
Identity = 22/61 (36.07%), Postives = 33/61 (54.10%), Query Frame = 3
Query:  672 MLTFILDLLNHPYFEP-CIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRY 851
            +  FI DLL  P   P  +KWED++   F+ + S  VA  W   K N + ++E  +R +RY
Sbjct:    5 LWEFIRDLLLQPEQNPGLLKWEDRRQGVFRFVKSDAVARLWGKKKNNSSMTYEKLSRAMRY 65          
BLAST of SMED30002579 vs. Ensembl Nematostella
Match: EDO45361 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSZ8])

HSP 1 Score: 48.1358 bits (113), Expect = 1.933e-7
Identity = 30/93 (32.26%), Postives = 47/93 (50.54%), Query Frame = 3
Query:  639 RPRDAPRNQIGMLTFILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNK 917
            RPR   +N I +  F+L+LL    +   I W  K+   FK+ N + VA  W I+K     ++E  +R IRY    G  K++   ++  Y+F K
Sbjct:    6 RPR--YKNTIHLWEFLLELLADERYSSLIAWSRKEYGEFKLKNQEEVAKRWGILKHRAGMNYEKLSRAIRYYYQQGIIKKVP-GQRLVYKFGK 95          
BLAST of SMED30002579 vs. Ensembl Nematostella
Match: EDO44339 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW27])

HSP 1 Score: 43.1282 bits (100), Expect = 9.464e-6
Identity = 23/82 (28.05%), Postives = 43/82 (52.44%), Query Frame = 3
Query:  666 IGMLTFILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQF 911
            I +  F+LDLL    +   I W +++S  FK++N + VA  W  +K     +++  +R +RY    G  K++  ++   Y+F
Sbjct:    3 IHLWEFLLDLLADGRYSSIISWTNRESGEFKLLNQEEVARRWGHLKHRPGMNYDKLSRALRYYYQKGIIKKVHGQRL-VYKF 83          
BLAST of SMED30002579 vs. Ensembl Medaka
Match: elf3 (ETS-related transcription factor Elf-3 [Source:NCBI gene;Acc:101162593])

HSP 1 Score: 52.373 bits (124), Expect = 3.748e-7
Identity = 30/94 (31.91%), Postives = 51/94 (54.26%), Query Frame = 3
Query:  645 RDAPRNQIGMLTFILDLLNHPYF-EPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKS 923
            + APR    +  FI D+L HP   +  +KWED++   FK + S+ VA  W   K+N + ++E  +R +RY       +++D ++   Y+F K S
Sbjct:  341 KHAPRG-THLWEFIRDILIHPEKNQGLMKWEDRREGVFKFLKSEAVAQMWGQKKKNSSMTYEKLSRAMRYYYKREILERVDGRR-LVYKFGKNS 432          
BLAST of SMED30002579 vs. Planmine SMEST
Match: SMESG000069596.1 (SMESG000069596.1)

HSP 1 Score: 671.774 bits (1732), Expect = 0.000e+0
Identity = 326/326 (100.00%), Postives = 326/326 (100.00%), Query Frame = 3
Query:   27 MDSEDFNHDIIFNDIFCGNCEEVDWEDLSDLIIANSECYHELEINSNYDIFQNSQNSSSSGLEVESNLENDMLLESINSYRDGMWSDSTSSIQKDFINLVKNYELKEFNKTFVEKYFILYNCPLDDILKKSRSQLWMDNCIYGLQLQVYICMVNDYPIPTVQHRNRKVPIQSKSGTSKKKGIVCDRLLEYLQSNCKSDSRVANVRPRDAPRNQIGMLTFILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKSIQTYKSKRQNNNLTRVLIDNFELRFDS 1004
            MDSEDFNHDIIFNDIFCGNCEEVDWEDLSDLIIANSECYHELEINSNYDIFQNSQNSSSSGLEVESNLENDMLLESINSYRDGMWSDSTSSIQKDFINLVKNYELKEFNKTFVEKYFILYNCPLDDILKKSRSQLWMDNCIYGLQLQVYICMVNDYPIPTVQHRNRKVPIQSKSGTSKKKGIVCDRLLEYLQSNCKSDSRVANVRPRDAPRNQIGMLTFILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKSIQTYKSKRQNNNLTRVLIDNFELRFDS
Sbjct:    1 MDSEDFNHDIIFNDIFCGNCEEVDWEDLSDLIIANSECYHELEINSNYDIFQNSQNSSSSGLEVESNLENDMLLESINSYRDGMWSDSTSSIQKDFINLVKNYELKEFNKTFVEKYFILYNCPLDDILKKSRSQLWMDNCIYGLQLQVYICMVNDYPIPTVQHRNRKVPIQSKSGTSKKKGIVCDRLLEYLQSNCKSDSRVANVRPRDAPRNQIGMLTFILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKSIQTYKSKRQNNNLTRVLIDNFELRFDS 326          
BLAST of SMED30002579 vs. Planmine SMEST
Match: SMESG000069596.1 (SMESG000069596.1)

HSP 1 Score: 529.25 bits (1362), Expect = 0.000e+0
Identity = 255/255 (100.00%), Postives = 255/255 (100.00%), Query Frame = 3
Query:  240 MLLESINSYRDGMWSDSTSSIQKDFINLVKNYELKEFNKTFVEKYFILYNCPLDDILKKSRSQLWMDNCIYGLQLQVYICMVNDYPIPTVQHRNRKVPIQSKSGTSKKKGIVCDRLLEYLQSNCKSDSRVANVRPRDAPRNQIGMLTFILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKSIQTYKSKRQNNNLTRVLIDNFELRFDS 1004
            MLLESINSYRDGMWSDSTSSIQKDFINLVKNYELKEFNKTFVEKYFILYNCPLDDILKKSRSQLWMDNCIYGLQLQVYICMVNDYPIPTVQHRNRKVPIQSKSGTSKKKGIVCDRLLEYLQSNCKSDSRVANVRPRDAPRNQIGMLTFILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKSIQTYKSKRQNNNLTRVLIDNFELRFDS
Sbjct:    1 MLLESINSYRDGMWSDSTSSIQKDFINLVKNYELKEFNKTFVEKYFILYNCPLDDILKKSRSQLWMDNCIYGLQLQVYICMVNDYPIPTVQHRNRKVPIQSKSGTSKKKGIVCDRLLEYLQSNCKSDSRVANVRPRDAPRNQIGMLTFILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKSIQTYKSKRQNNNLTRVLIDNFELRFDS 255          
BLAST of SMED30002579 vs. Planmine SMEST
Match: SMESG000069597.1 (SMESG000069597.1)

HSP 1 Score: 300.827 bits (769), Expect = 3.213e-101
Identity = 155/299 (51.84%), Postives = 204/299 (68.23%), Query Frame = 3
Query:   54 IIFNDIFCGNCEEVDWEDLSDLIIANSECYHELEINSNYDIFQNSQNSSSSGLEVESNLENDMLLESINSYRDGMWSDSTSSIQKDFINLVKNYELKEFNKTFVEKYFILYNCPLDDILKKSRSQLWMDNCIYGLQLQVYICMVNDYPIPTVQHRNRKVPI-QSKSGTSKKKGIVCDRLLEYLQSNCKSDSRVANVRPRDAPRNQIGMLTFILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKSIQTYKSKR 947
            +IFNDIF G+       D ++ +I +                 N++ S    L  + NLE + L++  +   D +  + +  IQ +F+N +K+ EL  + +TF+EKYF  Y CP D I++++R+QLWM+NCIYGLQLQ YICMV D P+P V  RNRK PI + K+ T  +KG+  D +LEYL   C++ S   + R RDAPRNQIG+L FILDLLNHPY++ CI+W DK SL FKIINSKLVAYYWM+VKENDTC+FENFARGIRYLR  G+FKQI+ K QRTYQFNKK+I+ Y+ KR
Sbjct:    1 MIFNDIFFGDI------DCTENVIGS-----------------NNEISDEDSLPQDFNLE-ETLIDETDICVDYICPEDSIIIQNNFVNFMKSQELHLYKETFIEKYFTSYKCPTDHIVQRTRTQLWMENCIYGLQLQAYICMVKDIPLPIVPQRNRKQPILKKKNLTQARKGVFQDVVLEYLFQKCRNVSEFVSFRHRDAPRNQIGLLIFILDLLNHPYYKGCIRWVDKGSLIFKIINSKLVAYYWMVVKENDTCNFENFARGIRYLRRVGFFKQINKKAQRTYQFNKKAIKEYEKKR 275          
BLAST of SMED30002579 vs. Planmine SMEST
Match: SMESG000035130.1 (SMESG000035130.1)

HSP 1 Score: 137.502 bits (345), Expect = 9.169e-38
Identity = 86/235 (36.60%), Postives = 131/235 (55.74%), Query Frame = 3
Query:  294 SSIQKDFINLVKNYELKEFNKTFVEKYF--ILYNCPLDDILKKSRSQLWMDNCIYGLQLQVYICMVNDYPIPTVQHRNRKVPI--QSKSGTSKKKGIV-CDRLLEYLQSNCKSDSRVANVRPRDAPRNQIGMLTFILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRY-LRHWGYFKQIDMKKQRTYQFNKKSIQTYKSKRQNNNLTRVLID 980
            SSI   FI  + + E + F++TF  KYF    ++   ++++  +R   W  +  YGL  Q +I    +  +P ++ RNRK+PI  +    + K KG    D + + L  NCK   +      R +PR+Q+ +  FILDLL HPY+  CI W +K   TF+I NS+ VA+ WM +K NDTC++ENFARGIR+  R+   F + +   +  YQ  K +I  YK KR  N L + L++
Sbjct:   63 SSILSKFIRYMCSKENEFFSETFCHKYFKRSRFSEYPEELINLNRVDAWNIDWAYGLVYQAFIAQEYNLELPCLKKRNRKIPIIGEKLKRSYKSKGYYDKDPIYDELIKNCKLTEK--EDYKRKSPRDQVLLHIFILDLLMHPYYGFCITWSNKNDFTFEIKNSRAVAHIWMTIKGNDTCNYENFARGIRFKRRNSNMFTRTNKHNRCVYQLTKTAIHDYKVKRSKNELAKQLME 295          
BLAST of SMED30002579 vs. Planmine SMEST
Match: SMESG000035130.1 (SMESG000035130.1)

HSP 1 Score: 137.502 bits (345), Expect = 1.043e-37
Identity = 86/235 (36.60%), Postives = 131/235 (55.74%), Query Frame = 3
Query:  294 SSIQKDFINLVKNYELKEFNKTFVEKYF--ILYNCPLDDILKKSRSQLWMDNCIYGLQLQVYICMVNDYPIPTVQHRNRKVPI--QSKSGTSKKKGIV-CDRLLEYLQSNCKSDSRVANVRPRDAPRNQIGMLTFILDLLNHPYFEPCIKWEDKKSLTFKIINSKLVAYYWMIVKENDTCSFENFARGIRY-LRHWGYFKQIDMKKQRTYQFNKKSIQTYKSKRQNNNLTRVLID 980
            SSI   FI  + + E + F++TF  KYF    ++   ++++  +R   W  +  YGL  Q +I    +  +P ++ RNRK+PI  +    + K KG    D + + L  NCK   +      R +PR+Q+ +  FILDLL HPY+  CI W +K   TF+I NS+ VA+ WM +K NDTC++ENFARGIR+  R+   F + +   +  YQ  K +I  YK KR  N L + L++
Sbjct:   69 SSILSKFIRYMCSKENEFFSETFCHKYFKRSRFSEYPEELINLNRVDAWNIDWAYGLVYQAFIAQEYNLELPCLKKRNRKIPIIGEKLKRSYKSKGYYDKDPIYDELIKNCKLTEK--EDYKRKSPRDQVLLHIFILDLLMHPYYGFCITWSNKNDFTFEIKNSRAVAHIWMTIKGNDTCNYENFARGIRFKRRNSNMFTRTNKHNRCVYQLTKTAIHDYKVKRSKNELAKQLME 301          
The following BLAST results are available for this feature:
BLAST of SMED30002579 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ELF57.034e-727.59E74 like ETS transcription factor 5 [Source:HGNC S... [more]
ELF31.251e-631.25E74 like ETS transcription factor 3 [Source:HGNC S... [more]
ELF31.251e-631.25E74 like ETS transcription factor 3 [Source:HGNC S... [more]
ELF31.251e-631.25E74 like ETS transcription factor 3 [Source:HGNC S... [more]
ELF51.494e-627.59E74 like ETS transcription factor 5 [Source:HGNC S... [more]
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BLAST of SMED30002579 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ets-48.736e-628.92Transcription factor ets-4 [Source:UniProtKB/Swis... [more]
ets-48.736e-628.92Transcription factor ets-4 [Source:UniProtKB/Swis... [more]
ets-48.736e-628.92Transcription factor ets-4 [Source:UniProtKB/Swis... [more]
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BLAST of SMED30002579 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30002579 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
elf31.956e-729.81E74-like factor 3 (ets domain transcription factor... [more]
elf32.364e-729.81E74-like factor 3 (ets domain transcription factor... [more]
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BLAST of SMED30002579 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSXETT00000020719.13.533e-631.71E74 like ETS transcription factor 3 [Source:NCBI g... [more]
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BLAST of SMED30002579 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Elf38.368e-731.91E74-like factor 3 [Source:MGI Symbol;Acc:MGI:11017... [more]
Elf38.438e-731.91E74-like factor 3 [Source:MGI Symbol;Acc:MGI:11017... [more]
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BLAST of SMED30002579 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q3UPW2|ELF3_MOUSE5.853e-631.91ETS-related transcription factor Elf-3 OS=Mus musc... [more]
sp|P78545|ELF3_HUMAN6.009e-631.25ETS-related transcription factor Elf-3 OS=Homo sap... [more]
sp|Q4V7E1|ELF3_RAT7.375e-631.91ETS-related transcription factor Elf-3 OS=Rattus n... [more]
sp|Q9UKW6|ELF5_HUMAN8.796e-627.59ETS-related transcription factor Elf-5 OS=Homo sap... [more]
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BLAST of SMED30002579 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8GPB93.759e-938.55ETS domain-containing protein OS=Macrostomum ligna... [more]
A0A267F0N93.967e-938.55ETS domain-containing protein OS=Macrostomum ligna... [more]
A0A267GQD54.113e-938.55ETS domain-containing protein OS=Macrostomum ligna... [more]
A0A1I8FYC84.162e-938.55ETS domain-containing protein OS=Macrostomum ligna... [more]
A0A267FLW34.398e-736.05Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of SMED30002579 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
elf31.291e-629.81E74 like ETS transcription factor 3 [Source:NCBI g... [more]
elf31.317e-629.81E74 like ETS transcription factor 3 [Source:NCBI g... [more]
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BLAST of SMED30002579 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ehf2.575e-736.07ets homologous factor [Source:ZFIN;Acc:ZDB-GENE-06... [more]
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BLAST of SMED30002579 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30002579 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO453611.933e-732.26Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO443399.464e-628.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of SMED30002579 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
elf33.748e-731.91ETS-related transcription factor Elf-3 [Source:NCB... [more]
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BLAST of SMED30002579 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000069596.10.000e+0100.00SMESG000069596.1[more]
SMESG000069596.10.000e+0100.00SMESG000069596.1[more]
SMESG000069597.13.213e-10151.84SMESG000069597.1[more]
SMESG000035130.19.169e-3836.60SMESG000035130.1[more]
SMESG000035130.11.043e-3736.60SMESG000035130.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002579 ID=SMED30002579|Name=SMED30002579|organism=Schmidtea mediterranea sexual|type=transcript|length=1071bp
TAATTTTCAAATTTTTTTTGTAAAAAATGGATTCAGAAGATTTTAATCAT
GATATTATTTTCAATGACATATTCTGTGGAAACTGCGAAGAAGTTGATTG
GGAAGACTTAAGCGATTTAATTATTGCTAATTCCGAATGTTATCATGAAT
TGGAAATCAATTCCAATTATGACATTTTTCAAAACAGTCAAAATTCTTCG
TCATCGGGTCTGGAAGTTGAAAGCAACTTGGAAAATGATATGTTATTGGA
ATCGATCAACAGTTACAGAGACGGAATGTGGTCGGATAGTACAAGTAGTA
TTCAGAAAGATTTCATTAACTTGGTCAAAAATTATGAATTGAAAGAGTTC
AATAAAACGTTTGTGGAAAAATATTTCATTCTCTACAATTGTCCATTGGA
TGACATATTGAAAAAATCTCGATCCCAGCTATGGATGGACAATTGCATCT
ACGGATTACAGCTGCAGGTCTACATATGCATGGTGAACGATTATCCCATA
CCTACTGTACAACACAGAAATCGTAAAGTTCCAATTCAAAGCAAAAGCGG
AACATCGAAAAAGAAGGGCATCGTATGTGACCGTCTTTTGGAATATTTGC
AAAGTAACTGTAAAAGTGATTCCAGAGTGGCCAATGTCAGACCCCGCGAT
GCGCCCAGAAATCAAATAGGAATGCTGACTTTTATATTAGATTTACTTAA
CCATCCATATTTCGAACCTTGCATTAAATGGGAAGATAAAAAGTCTCTTA
CCTTTAAGATCATCAATTCCAAACTGGTAGCTTACTACTGGATGATTGTG
AAAGAAAATGATACTTGCAGTTTTGAAAACTTTGCCCGAGGAATCAGATA
TTTACGTCATTGGGGTTATTTTAAACAAATTGATATGAAGAAACAGCGCA
CATATCAGTTCAATAAAAAGTCCATTCAGACATATAAAAGTAAAAGACAA
AATAATAACCTTACGAGAGTTTTAATTGATAATTTTGAACTAAGATTTGA
TTCCTAGCCATATTTTATAAATATCTTTTCAAATTAAACCATTTATACAT
ATCATTTTAGATTAAATTTGG
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protein sequence of SMED30002579-orf-1

>SMED30002579-orf-1 ID=SMED30002579-orf-1|Name=SMED30002579-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=327bp
MDSEDFNHDIIFNDIFCGNCEEVDWEDLSDLIIANSECYHELEINSNYDI
FQNSQNSSSSGLEVESNLENDMLLESINSYRDGMWSDSTSSIQKDFINLV
KNYELKEFNKTFVEKYFILYNCPLDDILKKSRSQLWMDNCIYGLQLQVYI
CMVNDYPIPTVQHRNRKVPIQSKSGTSKKKGIVCDRLLEYLQSNCKSDSR
VANVRPRDAPRNQIGMLTFILDLLNHPYFEPCIKWEDKKSLTFKIINSKL
VAYYWMIVKENDTCSFENFARGIRYLRHWGYFKQIDMKKQRTYQFNKKSI
QTYKSKRQNNNLTRVLIDNFELRFDS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0002032epidermal cell
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR036388WH-like_DNA-bd_sf
IPR036390WH_DNA-bd_sf
IPR000418Ets_dom
IPR011991WHTH_DNA-bd_dom
Vocabulary: molecular function
TermDefinition
GO:0003700transcription factor activity, sequence-specific DNA binding
GO:0043565sequence-specific DNA binding
GO:0003677DNA binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
GO:0006366transcription from RNA polymerase II promoter
GO:0006954inflammatory response
GO:0030855epithelial cell differentiation
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000418Ets domainSMARTSM00413etsneu2coord: 213..300
e-value: 4.1E-6
score: 25.2
IPR000418Ets domainPFAMPF00178Etscoord: 217..295
e-value: 3.4E-15
score: 56.3
IPR000418Ets domainPROSITEPS50061ETS_DOMAIN_3coord: 214..296
score: 9.929
IPR036388Winged helix-like DNA-binding domain superfamilyGENE3DG3DSA:1.10.10.10coord: 201..318
e-value: 7.0E-17
score: 63.2
NoneNo IPR availablePANTHERPTHR11849ETScoord: 177..299
IPR036390Winged helix DNA-binding domain superfamilySUPERFAMILYSSF46785"Winged helix" DNA-binding domaincoord: 199..302