26S proteasome regulatory subunit N11

Overview
Name26S proteasome regulatory subunit N11
Smed IDSMED30002574
Length (bp)1018
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of 26S proteasome regulatory subunit N11 (SMED30002574) t-SNE clustered cells

Violin plots show distribution of expression levels for 26S proteasome regulatory subunit N11 (SMED30002574) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of 26S proteasome regulatory subunit N11 (SMED30002574) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for 26S proteasome regulatory subunit N11 (SMED30002574) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30002574

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 14

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30002574h1SMcG0006342 Contig43381uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30002574h1SMcG0006342 Contig43381newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30002574h1SMcG0006342 dd_Smed_v4_2126_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30002574h1SMcG0006342 dd_Smed_v4_2126_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30002574h1SMcG0006342 dd_Smed_v4_2126_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30002574h1SMcG0006342 dd_Smed_v4_2126_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30002574h1SMcG0006342 dd_Smed_v4_2126_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30002574h1SMcG0006342 dd_Smed_v4_2126_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30002574h1SMcG0006342 dd_Smed_v4_2126_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30002574h1SMcG0006342 dd_Smed_v4_2126_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30002574h1SMcG0006342 dd_Smed_v4_2126_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30002574h1SMcG0006342 Contig46560newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30002574h1SMcG0006342 Contig46560uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
neoblastSMED30002574h1SMcG0006342 dd_Smed_v6_2126_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Human
Match: PSMD14 (proteasome 26S subunit, non-ATPase 14 [Source:HGNC Symbol;Acc:HGNC:16889])

HSP 1 Score: 469.929 bits (1208), Expect = 2.159e-167
Identity = 233/291 (80.07%), Postives = 255/291 (87.63%), Query Frame = 2 
Query:   83 TDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            TD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+N N ++   EPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W + LTL DY EH   N+  +K ML L K Y K++E+E+KMTPEQLAIKNVGK DPKRHL EHVD LMT+NI Q L +M+  +VF+
Sbjct:   20 TDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 310
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Human
Match: COPS5 (COP9 signalosome subunit 5 [Source:HGNC Symbol;Acc:HGNC:2240])

HSP 1 Score: 130.568 bits (327), Expect = 1.281e-34
Identity = 82/215 (38.14%), Postives = 122/215 (56.74%), Query Frame = 2 
Query:   98 PDTAEHIY-----ISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFRLMNPNHVIANQEPRQ-TTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLT 715
            P T +H Y     IS+LALLKM+ H R+G  +EVMGLMLG+   +  + +   FA+P  GT   V A    ++     ++  KQ GR E  +GWYHSHPG+GCWLSG+D++TQ   +Q  E  VAVVIDP +++  GKV + AFR     +   ++ P +  T  L  ++   +        + YY+L + Y K+ L++K+L  L  K W + L+
Sbjct:   44 PWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDS-FALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVSYFKSSLDRKLLELLWNKYWVNTLS 251
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Human
Match: COPS5 (COP9 signalosome subunit 5 [Source:HGNC Symbol;Acc:HGNC:2240])

HSP 1 Score: 116.316 bits (290), Expect = 1.309e-30
Identity = 71/194 (36.60%), Postives = 109/194 (56.19%), Query Frame = 2 
Query:  146 MLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFRLMNPNHVIANQEPRQ-TTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLT 715
            M+ H R+G  +EVMGLMLG+   +  + +   FA+P  GT   V A    ++     ++  KQ GR E  +GWYHSHPG+GCWLSG+D++TQ   +Q  E  VAVVIDP +++  GKV + AFR     +   ++ P +  T  L  ++   +        + YY+L + Y K+ L++K+L  L  K W + L+
Sbjct:    1 MVMHARSGGNLEVMGLMLGKVDGETMIIMDS-FALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVSYFKSSLDRKLLELLWNKYWVNTLS 187
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Human
Match: PSMD14 (proteasome 26S subunit, non-ATPase 14 [Source:HGNC Symbol;Acc:HGNC:16889])

HSP 1 Score: 99.3673 bits (246), Expect = 1.555e-25
Identity = 58/65 (89.23%), Postives = 60/65 (92.31%), Query Frame = 2 
Query:   83 TDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSV 277
            TD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSV
Sbjct:   20 TDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSV 84
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Human
Match: COPS5 (COP9 signalosome subunit 5 [Source:HGNC Symbol;Acc:HGNC:2240])

HSP 1 Score: 100.138 bits (248), Expect = 5.492e-25
Identity = 56/124 (45.16%), Postives = 78/124 (62.90%), Query Frame = 2 
Query:  146 MLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFR 508
            M+ H R+G  +EVMGLMLG+   +  + +   FA+P  GT   V A    ++     ++  KQ GR E  +GWYHSHPG+GCWLSG+D++TQ   +Q  E  VAVVIDP +++  GKV + AFR
Sbjct:    1 MVMHARSGGNLEVMGLMLGKVDGETMIIMDS-FALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFR 123
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Celegans
Match: rpn-11 (26S proteasome non-ATPase regulatory subunit 14 [Source:UniProtKB/Swiss-Prot;Acc:O76577])

HSP 1 Score: 439.499 bits (1129), Expect = 9.119e-156
Identity = 219/292 (75.00%), Postives = 248/292 (84.93%), Query Frame = 2 
Query:   80 PTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            P D    DT+E +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LS+RAVAVV+DPIQSVKGKVVIDAFR +NP  +  NQEPRQTTSNLGHLQKPSIQALIHGLNRHYYS+PI YR ++LEQKML+NL+K +W D +++ +Y +   +NKE LKAML L K Y K+LEDE+ MT ++LAIKNVGKMDPKRH+ + V K++  NI Q L  M+     Q
Sbjct:   21 PQDSNQVDTSETVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSDRAVAVVVDPIQSVKGKVVIDAFRTINPQSMALNQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSIPIAYRTHDLEQKMLLNLNKLSWMDAVSVENYSKCGEQNKEHLKAMLKLAKNYKKALEDEKNMTDQELAIKNVGKMDPKRHIADEVSKMLNDNIVQSLAGMMATTSLQ 312
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Celegans
Match: F37A4.5 (pep chromosome:WBcel235:III:6711869:6713191:1 gene:WBGene00018135.1 transcript:F37A4.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F37A4.5)

HSP 1 Score: 304.679 bits (779), Expect = 1.339e-102
Identity = 170/319 (53.29%), Postives = 216/319 (67.71%), Query Frame = 2 
Query:   23 MDQLLRIGGFPGLRQSNSAPTDG-PVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNH-----VIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTP-------EQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIH 940
            MD+L+R      L   N   TD    PDT+E + ISSLALLKML+H R+G+P+EVMGLMLG+FVDDYT+ V DVFAMPQSGT V+VE+VDPV+Q K +D+LK  GR E VVGWYHSHPGFGCWLS VD+NTQQSFE L  RAVAVV+DPIQSVKGKV++DAFR +NP +     +    EPRQTTSNLGHL KPS+ +++HGL   YYSL + YR    EQKMLM L+KK+W D L +  Y E   + +E  K++  L+  + K + DE K  P        Q  +K  GK++ K+ L      L+  ++   L +MI+
Sbjct:    1 MDRLIR----SLLMNQNKQATDKLDHPDTSETVNISSLALLKMLRHARSGIPLEVMGLMLGDFVDDYTINVTDVFAMPQSGTSVTVESVDPVYQTKHMDLLKLVGRTENVVGWYHSHPGFGCWLSSVDVNTQQSFEALHPRAVAVVVDPIQSVKGKVMLDAFRSVNPLNLQIRPLAPTAEPRQTTSNLGHLTKPSLISVVHGLGTKYYSLNVAYRMGSNEQKMLMCLNKKSWYDQLNMSTYSELEKKQEEKFKSINKLIAVFNKDI-DEVKEKPIADKKGKTQEEVKKFGKINAKQQLQMITSSLLNDSLCHQLTAMIN 314
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Celegans
Match: csn-5 (COP9 signalosome complex subunit 5 [Source:UniProtKB/Swiss-Prot;Acc:P91001])

HSP 1 Score: 123.25 bits (308), Expect = 4.850e-32
Identity = 76/219 (34.70%), Postives = 118/219 (53.88%), Query Frame = 2 
Query:   71 NSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKML--DMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFRLMNPNHVIANQEPRQTTS-NLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLT 715
            N+ P D   P   + I IS++ALLKM  H + G  +E+MGL+ G    +  + +   FA+P  GT   V A    ++   +  +M    GR E VVGWYHSHPG+GCWLSG+D++TQ   ++  E  VA+VIDP++++  GKV I AFR     +   +  P +  S  L  ++   +        + YYSL + + K++L+  +L +L    W   L+
Sbjct:   42 NAKPWDKD-PHYFKQIKISAIALLKMTMHAKRGGNLEIMGLLQGRIDANSFIILDV-FALPVEGTETRVNAQAQAYEYMTVYSEMCDTEGRKEKVVGWYHSHPGYGCWLSGIDVSTQTLNQKFQEPWVAIVIDPLRTMSAGKVDIGAFRTYPEGYRPPDDVPSEYQSIPLAKIEDFGVHC------KRYYSLDVSFFKSQLDAHILTSLWNSYWISTLS 252
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Fly
Match: Rpn11 (gene:FBgn0028694 transcript:FBtr0079027)

HSP 1 Score: 493.426 bits (1269), Expect = 4.841e-177
Identity = 248/311 (79.74%), Postives = 275/311 (88.42%), Query Frame = 2 
Query:   23 MDQLLRIGGFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            MD+LLR+GG   + Q+ + PTD PV DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQ+GTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+NPN ++  QEPRQTTSNLGHLQKPS+QALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W+D LTL DY EH + N++T+  ML L K Y KSLEDEEKMTPEQLAIKNVGK DPKRHL E VDK+M  NI Q LG+M+  +VF+
Sbjct:    1 MDRLLRLGG--AMPQA-APPTDAPVVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVQVIDVFAMPQTGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINPNMLVLGQEPRQTTSNLGHLQKPSVQALIHGLNRHYYSISINYRKNELEQKMLLNLHKKSWKDGLTLSDYNEHCSINEDTVAEMLDLAKNYNKSLEDEEKMTPEQLAIKNVGKQDPKRHLEEKVDKVMQNNIVQCLGAMLDTIVFK 308
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Fly
Match: CSN5 (gene:FBgn0027053 transcript:FBtr0334535)

HSP 1 Score: 138.658 bits (348), Expect = 4.612e-38
Identity = 81/209 (38.76%), Postives = 121/209 (57.89%), Query Frame = 2 
Query:   98 PDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQ--AKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFRLMNPNHVIANQEPRQ-TTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDL 712
            P   + I IS+LALLKM+ H R+G  +EVMGLMLG+  D+  + +   FA+P  GT   V A    ++     ++  K+ GR E  VGWYHSHPG+GCWLSG+D++TQ   +   E  VA+V+DP+++V  GKV + AFR     +   N+EP +  T  L  ++   +        + YY L I Y K+ L++++L +L  K W + L
Sbjct:   46 PHFFKDIKISALALLKMVMHARSGGTLEVMGLMLGKVEDNTMIVMDA-FALPVEGTETRVNAQAQAYEYMTAYMEAAKEVGRMEHAVGWYHSHPGYGCWLSGIDVSTQMLNQTYQEPFVAIVVDPVRTVSAGKVCLGAFRTYPKGYKPPNEEPSEYQTIPLNKIEDFGVHC------KQYYPLEISYFKSALDRRLLDSLWNKYWVNTL 247
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Fly
Match: CSN5 (gene:FBgn0027053 transcript:FBtr0083292)

HSP 1 Score: 138.658 bits (348), Expect = 5.407e-38
Identity = 81/209 (38.76%), Postives = 121/209 (57.89%), Query Frame = 2 
Query:   98 PDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQ--AKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFRLMNPNHVIANQEPRQ-TTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDL 712
            P   + I IS+LALLKM+ H R+G  +EVMGLMLG+  D+  + +   FA+P  GT   V A    ++     ++  K+ GR E  VGWYHSHPG+GCWLSG+D++TQ   +   E  VA+V+DP+++V  GKV + AFR     +   N+EP +  T  L  ++   +        + YY L I Y K+ L++++L +L  K W + L
Sbjct:   46 PHFFKDIKISALALLKMVMHARSGGTLEVMGLMLGKVEDNTMIVMDA-FALPVEGTETRVNAQAQAYEYMTAYMEAAKEVGRMEHAVGWYHSHPGYGCWLSGIDVSTQMLNQTYQEPFVAIVVDPVRTVSAGKVCLGAFRTYPKGYKPPNEEPSEYQTIPLNKIEDFGVHC------KQYYPLEISYFKSALDRRLLDSLWNKYWVNTL 247
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Zebrafish
Match: psmd14 (proteasome 26S subunit, non-ATPase 14 [Source:ZFIN;Acc:ZDB-GENE-070410-56])

HSP 1 Score: 482.641 bits (1241), Expect = 1.222e-172
Identity = 245/311 (78.78%), Postives = 268/311 (86.17%), Query Frame = 2 
Query:   23 MDQLLRIGG-FPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVF 952
            MD+LLR+GG  PGL Q    PTD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+N N ++   EPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W + LTL DY EH   N+  +K ML L K Y K++E+E+KMTPEQLAIKNVGK DPKRHL EHVD LMT+NI Q L +M+  +VF
Sbjct:    1 MDRLLRLGGGMPGLSQG--PPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKLNETIVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVF 309
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Zebrafish
Match: cops5 (COP9 signalosome subunit 5 [Source:NCBI gene;Acc:393698])

HSP 1 Score: 130.183 bits (326), Expect = 1.412e-34
Identity = 81/215 (37.67%), Postives = 122/215 (56.74%), Query Frame = 2 
Query:   98 PDTAEHIY-----ISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFRLMNPNHVIANQEPRQ-TTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLT 715
            P T +H Y     +S+LALLKM+ H R+G  +EVMGLMLG+   +  + +   FA+P  GT   V A    ++     ++  KQ GR E  +GWYHSHPG+GCWLSG+D++TQ   +Q  E  VAVVIDP +++  GKV + AFR     +   ++ P +  T  L  ++   +        + YY+L + Y K+ L++K+L  L  K W + L+
Sbjct:   42 PWTKDHHYFKYCKLSALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDS-FALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVSYFKSSLDRKLLELLWNKYWVNTLS 249
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Zebrafish
Match: brcc3 (BRCA1/BRCA2-containing complex, subunit 3 [Source:ZFIN;Acc:ZDB-GENE-100215-1])

HSP 1 Score: 60.4622 bits (145), Expect = 3.527e-10
Identity = 40/141 (28.37%), Postives = 68/141 (48.23%), Query Frame = 2 
Query:  116 IYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDP------VFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVV----IDPIQSVKGKVVIDAFR 508
            +++ S A L  + H  +    EVMGL +GE   +  V +  V  + +S        + P        +A++  + + TGRP  VVGWYHSHP    W S VD+ TQ  ++ + +  V ++    I+   +  G+V+   F+
Sbjct:   33 VHLESDAFLVCMNHALSTEKEEVMGLCIGEVDTNRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAEISRLAEMTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQ 173
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Zebrafish
Match: eif3ha (eukaryotic translation initiation factor 3, subunit H, a [Source:NCBI gene;Acc:445306])

HSP 1 Score: 60.077 bits (144), Expect = 9.283e-10
Identity = 45/150 (30.00%), Postives = 82/150 (54.67%), Query Frame = 2 
Query:   68 SNSAPTDGPVPDTAEHIYISSLALLKMLKHGRA-GVPMEVM-GLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRL 511
            S S P D PV    + I +  L +LK++KH +  G   EV+ G++LG  V +  + + + F  PQ  T   VE  +  +Q +M+  L+      + VGWY S   +G ++S   +++Q S++   E +V ++ DP+++ +G + + A+RL
Sbjct:   10 SGSNPLDFPV----KQIQVDGLVVLKIIKHYQEEGQGSEVVQGVLLG-LVVEDRLEITNCFPFPQH-TEDDVEFDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVSRALLDSQFSYQHAIEESVVLIYDPLKTAQGSLCLKAYRL 152
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Zebrafish
Match: brcc3 (BRCA1/BRCA2-containing complex, subunit 3 [Source:ZFIN;Acc:ZDB-GENE-100215-1])

HSP 1 Score: 58.151 bits (139), Expect = 2.968e-9
Identity = 39/139 (28.06%), Postives = 65/139 (46.76%), Query Frame = 2 
Query:  116 IYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDP----VFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVV----IDPIQSVKGKVVIDAFR 508
            +++ S A L  + H  +    EVMGL +GE   +  V +  V  + +S        + P        +   + + TGRP  VVGWYHSHP    W S VD+ TQ  ++ + +  V ++    I+   +  G+V+   F+
Sbjct:    7 VHLESDAFLVCMNHALSTEKEEVMGLCIGEVDTNRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAEMTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQ 145
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Xenopus
Match: prokr2 (prokineticin receptor 2 [Source:Xenbase;Acc:XB-GENE-490581])

HSP 1 Score: 468.389 bits (1204), Expect = 3.688e-167
Identity = 233/292 (79.79%), Postives = 256/292 (87.67%), Query Frame = 2 
Query:   80 PTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            PTD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+N N ++   EPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W + LTL +Y EH   N+  +K ML L K Y K++E+E+KMTPEQLAIKNVGK DPKRHL EHVD LMT+NI Q L +M+  +VF+
Sbjct:    5 PTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQNYSEHCKLNETVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 296
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Xenopus
Match: prokr2 (prokineticin receptor 2 [Source:Xenbase;Acc:XB-GENE-490581])

HSP 1 Score: 468.389 bits (1204), Expect = 7.034e-167
Identity = 233/292 (79.79%), Postives = 256/292 (87.67%), Query Frame = 2 
Query:   80 PTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            PTD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+N N ++   EPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W + LTL +Y EH   N+  +K ML L K Y K++E+E+KMTPEQLAIKNVGK DPKRHL EHVD LMT+NI Q L +M+  +VF+
Sbjct:   22 PTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQNYSEHCKLNETVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 313
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Xenopus
Match: prokr2 (prokineticin receptor 2 [Source:Xenbase;Acc:XB-GENE-490581])

HSP 1 Score: 467.233 bits (1201), Expect = 1.972e-166
Identity = 232/291 (79.73%), Postives = 255/291 (87.63%), Query Frame = 2 
Query:   83 TDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            TD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+N N ++   EPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W + LTL +Y EH   N+  +K ML L K Y K++E+E+KMTPEQLAIKNVGK DPKRHL EHVD LMT+NI Q L +M+  +VF+
Sbjct:   20 TDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQNYSEHCKLNETVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 310
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Xenopus
Match: prokr2 (prokineticin receptor 2 [Source:Xenbase;Acc:XB-GENE-490581])

HSP 1 Score: 405.601 bits (1041), Expect = 1.533e-142
Identity = 210/291 (72.16%), Postives = 232/291 (79.73%), Query Frame = 2 
Query:   83 TDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            TD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+N N ++   EPRQTTSNLGHL KPSIQ                         ML+NLHKK+W + LTL +Y EH   N+  +K ML L K Y K++E+E+KMTPEQLAIKNVGK DPKRHL EHVD LMT+NI Q L +M+  +VF+
Sbjct:   20 TDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQ-------------------------MLLNLHKKSWMEGLTLQNYSEHCKLNETVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 285
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Xenopus
Match: cops5 (COP9 signalosome subunit 5 [Source:NCBI gene;Acc:394714])

HSP 1 Score: 130.183 bits (326), Expect = 2.511e-34
Identity = 81/215 (37.67%), Postives = 122/215 (56.74%), Query Frame = 2 
Query:   98 PDTAEHIY-----ISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFRLMNPNHVIANQEPRQ-TTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLT 715
            P T +H Y     +S+LALLKM+ H R+G  +EVMGLMLG+   +  + +   FA+P  GT   V A    ++     ++  KQ GR E  +GWYHSHPG+GCWLSG+D++TQ   +Q  E  VAVVIDP +++  GKV + AFR     +   ++ P +  T  L  ++   +        + YY+L + Y K+ L++K+L  L  K W + L+
Sbjct:   52 PWTKDHHYFKYCKVSALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDS-FALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVTYFKSSLDRKLLELLWNKYWVNTLS 259
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Mouse
Match: Psmd14 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 [Source:MGI Symbol;Acc:MGI:1913284])

HSP 1 Score: 469.929 bits (1208), Expect = 1.482e-167
Identity = 233/291 (80.07%), Postives = 255/291 (87.63%), Query Frame = 2 
Query:   83 TDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            TD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+N N ++   EPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W + LTL DY EH   N+  +K ML L K Y K++E+E+KMTPEQLAIKNVGK DPKRHL EHVD LMT+NI Q L +M+  +VF+
Sbjct:   20 TDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 310
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Mouse
Match: Cops5 (COP9 signalosome subunit 5 [Source:MGI Symbol;Acc:MGI:1349415])

HSP 1 Score: 130.954 bits (328), Expect = 7.524e-35
Identity = 82/215 (38.14%), Postives = 122/215 (56.74%), Query Frame = 2 
Query:   98 PDTAEHIY-----ISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFRLMNPNHVIANQEPRQ-TTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLT 715
            P T +H Y     IS+LALLKM+ H R+G  +EVMGLMLG+   +  + +   FA+P  GT   V A    ++     ++  KQ GR E  +GWYHSHPG+GCWLSG+D++TQ   +Q  E  VAVVIDP +++  GKV + AFR     +   ++ P +  T  L  ++   +        + YY+L + Y K+ L++K+L  L  K W + L+
Sbjct:   44 PWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDS-FALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVSYFKSSLDRKLLELLWNKYWVNTLS 251
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Mouse
Match: Cops5 (COP9 signalosome subunit 5 [Source:MGI Symbol;Acc:MGI:1349415])

HSP 1 Score: 114.005 bits (284), Expect = 9.280e-30
Identity = 70/158 (44.30%), Postives = 94/158 (59.49%), Query Frame = 2 
Query:   74 SAPTDGPVPD--TAEHIY--------ISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFR 508
            S PT  PV     A  +Y        IS+LALLKM+ H R+G  +EVMGLMLG+   +  + +   FA+P  GT   V A    ++     ++  KQ GR E  +GWYHSHPG+GCWLSG+D++TQ   +Q  E  VAVVIDP +++  GKV + AFR
Sbjct:   14 SGPTSPPVSSVMAALRVYHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDS-FALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFR 170
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Mouse
Match: Cops5 (COP9 signalosome subunit 5 [Source:MGI Symbol;Acc:MGI:1349415])

HSP 1 Score: 107.071 bits (266), Expect = 8.429e-28
Identity = 65/128 (50.78%), Postives = 88/128 (68.75%), Query Frame = 2 
Query:  134 ALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGT--GVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFR 508
            ALLKM+ H R+G  +EVMGLMLG+ VD  T+ ++D FA+P  GT   V+ +A    + A  ++  KQ GR E  +GWYHSHPG+GCWLSG+D++TQ   +Q  E  VAVVIDP +++  GKV + AFR
Sbjct:    2 ALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFR 128
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Mouse
Match: Brcc3 (BRCA1/BRCA2-containing complex, subunit 3 [Source:MGI Symbol;Acc:MGI:2389572])

HSP 1 Score: 56.225 bits (134), Expect = 3.597e-9
Identity = 40/138 (28.99%), Postives = 63/138 (45.65%), Query Frame = 2 
Query:  119 YISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDP----VFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVV----IDPIQSVKGKVVIDAFR 508
            ++ S A L  L H  +    EVMGL +GE      V +  V  + +S        + P        +   + + TGRP  VVGWYHSHP    W S VD+ TQ  ++ + +  V ++    I+   +  G+V+   F+
Sbjct:   13 HLESDAFLVCLNHALSTEKEEVMGLCIGEMDTIRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQ 150
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. UniProt/SwissProt
Match: sp|Q9V3H2|PSDE_DROME (26S proteasome non-ATPase regulatory subunit 14 OS=Drosophila melanogaster OX=7227 GN=Rpn11 PE=1 SV=1)

HSP 1 Score: 493.426 bits (1269), Expect = 4.852e-176
Identity = 248/311 (79.74%), Postives = 275/311 (88.42%), Query Frame = 2 
Query:   23 MDQLLRIGGFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            MD+LLR+GG   + Q+ + PTD PV DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQ+GTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+NPN ++  QEPRQTTSNLGHLQKPS+QALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W+D LTL DY EH + N++T+  ML L K Y KSLEDEEKMTPEQLAIKNVGK DPKRHL E VDK+M  NI Q LG+M+  +VF+
Sbjct:    1 MDRLLRLGG--AMPQA-APPTDAPVVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVQVIDVFAMPQTGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINPNMLVLGQEPRQTTSNLGHLQKPSVQALIHGLNRHYYSISINYRKNELEQKMLLNLHKKSWKDGLTLSDYNEHCSINEDTVAEMLDLAKNYNKSLEDEEKMTPEQLAIKNVGKQDPKRHLEEKVDKVMQNNIVQCLGAMLDTIVFK 308
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. UniProt/SwissProt
Match: sp|O35593|PSDE_MOUSE (26S proteasome non-ATPase regulatory subunit 14 OS=Mus musculus OX=10090 GN=Psmd14 PE=1 SV=2)

HSP 1 Score: 469.929 bits (1208), Expect = 1.037e-166
Identity = 233/291 (80.07%), Postives = 255/291 (87.63%), Query Frame = 2 
Query:   83 TDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            TD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+N N ++   EPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W + LTL DY EH   N+  +K ML L K Y K++E+E+KMTPEQLAIKNVGK DPKRHL EHVD LMT+NI Q L +M+  +VF+
Sbjct:   20 TDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 310
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. UniProt/SwissProt
Match: sp|O00487|PSDE_HUMAN (26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1)

HSP 1 Score: 469.929 bits (1208), Expect = 1.037e-166
Identity = 233/291 (80.07%), Postives = 255/291 (87.63%), Query Frame = 2 
Query:   83 TDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            TD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+N N ++   EPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W + LTL DY EH   N+  +K ML L K Y K++E+E+KMTPEQLAIKNVGK DPKRHL EHVD LMT+NI Q L +M+  +VF+
Sbjct:   20 TDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 310
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. UniProt/SwissProt
Match: sp|Q9LT08|PSDE_ARATH (26S proteasome non-ATPase regulatory subunit 14 homolog OS=Arabidopsis thaliana OX=3702 GN=RPN11 PE=1 SV=1)

HSP 1 Score: 439.113 bits (1128), Expect = 1.086e-154
Identity = 221/310 (71.29%), Postives = 257/310 (82.90%), Query Frame = 2 
Query:   23 MDQLLRIGGFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVF 952
            M++L RI G  G      A  D P  DT+E +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVD+YTV VVDVFAMPQSGTGVSVEAVD VFQ  MLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE L++RAVAVV+DPIQSVKGKVVIDAFR +NP  ++  QEPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELE+KML+NLHKK W D LTL  +  HS  N++T++ MLSL   Y K++++E++++PE+LAI NVG+ D K+HL EHV  LM++NI Q LG+M+  +VF
Sbjct:    1 MERLQRIFGAGG--GLGHASPDSPTLDTSEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDEYTVRVVDVFAMPQSGTGVSVEAVDHVFQTNMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALNQRAVAVVVDPIQSVKGKVVIDAFRSINPQTIMLGQEPRQTTSNLGHLNKPSIQALIHGLNRHYYSIAINYRKNELEEKMLLNLHKKKWTDGLTLRRFDTHSKTNEQTVQEMLSLAAKYNKAVQEEDELSPEKLAIVNVGRQDAKKHLEEHVSNLMSSNIVQTLGTMLDTVVF 308
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. UniProt/SwissProt
Match: sp|O76577|PSDE_CAEEL (26S proteasome non-ATPase regulatory subunit 14 OS=Caenorhabditis elegans OX=6239 GN=rpn-11 PE=1 SV=1)

HSP 1 Score: 439.499 bits (1129), Expect = 1.160e-154
Identity = 219/292 (75.00%), Postives = 248/292 (84.93%), Query Frame = 2 
Query:   80 PTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            P D    DT+E +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LS+RAVAVV+DPIQSVKGKVVIDAFR +NP  +  NQEPRQTTSNLGHLQKPSIQALIHGLNRHYYS+PI YR ++LEQKML+NL+K +W D +++ +Y +   +NKE LKAML L K Y K+LEDE+ MT ++LAIKNVGKMDPKRH+ + V K++  NI Q L  M+     Q
Sbjct:   21 PQDSNQVDTSETVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSDRAVAVVVDPIQSVKGKVVIDAFRTINPQSMALNQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSIPIAYRTHDLEQKMLLNLNKLSWMDAVSVENYSKCGEQNKEHLKAMLKLAKNYKKALEDEKNMTDQELAIKNVGKMDPKRHIADEVSKMLNDNIVQSLAGMMATTSLQ 312
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. TrEMBL
Match: A0A183L327 (MPN domain-containing protein OS=Schistosoma curassoni OX=6186 GN=SCUD_LOCUS21733 PE=4 SV=1)

HSP 1 Score: 521.931 bits (1343), Expect = 0.000e+0
Identity = 261/312 (83.65%), Postives = 286/312 (91.67%), Query Frame = 2 
Query:   23 MDQLLRIG--GFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVF 952
            M++LLR+G  G   L QSN+ PTDGPVPDTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFQAKMLDML+QTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFE LS+RAVAVV+DPIQSVKGKVVIDAFRL+NPN VIANQEPRQTTSN+GHL KP+IQALIHGLNRHYYSLPI YRKN+ E KMLMNL+K+TW+D LTL DY  H   N +TL+ ML LVK+Y KSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVD+LMT+NI+Q LG+M+H++VF
Sbjct:    1 MERLLRLGADGLAALGQSNAQPTDGPVPDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFQAKMLDMLRQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEALSDRAVAVVVDPIQSVKGKVVIDAFRLINPNLVIANQEPRQTTSNVGHLSKPTIQALIHGLNRHYYSLPINYRKNKWEIKMLMNLNKRTWRDGLTLEDYNTHCTANHKTLQTMLDLVKSYHKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDELMTSNITQSLGAMLHSVVF 312
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. TrEMBL
Match: O16154 (Pad1 homolog OS=Schistosoma mansoni OX=6183 GN=SmPOH PE=2 SV=1)

HSP 1 Score: 521.931 bits (1343), Expect = 0.000e+0
Identity = 261/312 (83.65%), Postives = 287/312 (91.99%), Query Frame = 2 
Query:   23 MDQLLRIG--GFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVF 952
            M++LLR+G  G   L QSN+ PTDGPVPDTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFQAKMLDML+QTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFE LS+RAVAVV+DPIQSVKGKVVIDAFRL+NPN VIANQEPRQTTSN+GHL KP+IQALIHGLNRHYYSLPI YRKN+ E KMLMNL+K+TW+D LTL DY  H + N +TL+ ML LVK+Y KSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVD+LMT+NI+Q LG+M+H++VF
Sbjct:    1 MERLLRLGADGLAALGQSNAQPTDGPVPDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFQAKMLDMLRQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEALSDRAVAVVVDPIQSVKGKVVIDAFRLINPNLVIANQEPRQTTSNVGHLSKPTIQALIHGLNRHYYSLPINYRKNKWEIKMLMNLNKRTWRDGLTLEDYNTHCSANHKTLQTMLDLVKSYHKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDELMTSNITQSLGAMLHSVVF 312
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. TrEMBL
Match: C1L5Q3 (26S proteasome non-ATPase regulatory subunit 14 OS=Schistosoma japonicum OX=6182 GN=Rpn11 PE=2 SV=1)

HSP 1 Score: 521.161 bits (1341), Expect = 0.000e+0
Identity = 261/312 (83.65%), Postives = 287/312 (91.99%), Query Frame = 2 
Query:   23 MDQLLRIG--GFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVF 952
            M++LLR+G  G   L QSN+ PTDGPVPDTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFE LS+RAVAVV+DPIQSVKGKVVIDAFRL+NP+ VIANQEPRQTTSN+GHL KP+IQALIHGLNRHYYSLPI YRKN+ E KMLMNL+K+TW+D LTL DY  H + N +TL+ ML LVK+Y KSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVD+LMT+NI+Q LG+M+H++VF
Sbjct:    1 MERLLRLGADGLAALGQSNAQPTDGPVPDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEALSDRAVAVVVDPIQSVKGKVVIDAFRLINPSLVIANQEPRQTTSNVGHLSKPTIQALIHGLNRHYYSLPINYRKNKWEIKMLMNLNKRTWRDGLTLEDYNAHCSANHKTLQTMLDLVKSYHKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDELMTSNITQSLGAMLHSVVF 312
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. TrEMBL
Match: Q5DI41 (SJCHGC06520 protein OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 520.776 bits (1340), Expect = 0.000e+0
Identity = 261/312 (83.65%), Postives = 287/312 (91.99%), Query Frame = 2 
Query:   23 MDQLLRIG--GFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVF 952
            M++LLR+G  G   L QSN+ PTDGPVPDTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFE LS+RAVAVV+DPIQSVKGKVVIDAFRL+NP+ VIANQEPRQTTSN+GHL KP+IQALIHGLNRHYYSLPI YRKN+ E KMLMNL+K+TW+D LTL DY  H + N +TL+ ML LVK+Y KSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVD+LMT+NI+Q LG+M+H++VF
Sbjct:    1 MERLLRLGADGLAALGQSNAQPTDGPVPDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEALSDRAVAVVVDPIQSVKGKVVIDAFRLINPSLVIANQEPRQTTSNVGHLSKPTIQALIHGLNRHYYSLPINYRKNKWEIKMLMNLNKRTWRDGLTLEDYNAHCSANHKTLQTMLDLVKSYPKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDELMTSNITQFLGAMLHSVVF 312
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. TrEMBL
Match: C1L5Q1 (26S proteasome regulatory subunit N11 OS=Schistosoma japonicum OX=6182 GN=Rpn11 PE=2 SV=1)

HSP 1 Score: 519.235 bits (1336), Expect = 0.000e+0
Identity = 260/312 (83.33%), Postives = 286/312 (91.67%), Query Frame = 2 
Query:   23 MDQLLRIG--GFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVF 952
            M++LLR+G  G   L QSN+ PTDGPVPDTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVF AKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFE LS+RAVAVV+DPIQSVKGKVVIDAFRL+NP+ VIANQEPRQTTSN+GHL KP+IQALIHGLNRHYYSLPI YRKN+ E KMLMNL+K+TW+D LTL DY  H + N +TL+ ML LVK+Y KSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVD+LMT+NI+Q LG+M+H++VF
Sbjct:    1 MERLLRLGADGLAALGQSNAQPTDGPVPDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFSAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEALSDRAVAVVVDPIQSVKGKVVIDAFRLINPSLVIANQEPRQTTSNVGHLSKPTIQALIHGLNRHYYSLPINYRKNKWEIKMLMNLNKRTWRDGLTLEDYNAHCSANHKTLQTMLDLVKSYHKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDELMTSNITQSLGAMLHSVVF 312
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Cavefish
Match: psmd14 (proteasome 26S subunit, non-ATPase 14 [Source:NCBI gene;Acc:103034529])

HSP 1 Score: 470.315 bits (1209), Expect = 8.659e-168
Identity = 234/291 (80.41%), Postives = 255/291 (87.63%), Query Frame = 2 
Query:   83 TDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            TD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+N N ++   EPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W + LTL DY EH   N+  +K ML L K Y K++E+E+KMTPEQLAIKNVGK DPKRHL EHVD LMT+NI Q L +M+  +VFQ
Sbjct:   20 TDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINTNMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKLNETIVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFQ 310
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Cavefish
Match: cops5 (COP9 signalosome subunit 5 [Source:NCBI gene;Acc:103038559])

HSP 1 Score: 130.183 bits (326), Expect = 5.566e-35
Identity = 82/215 (38.14%), Postives = 122/215 (56.74%), Query Frame = 2 
Query:   98 PDTAEHIY-----ISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFRLMNPNHVIANQEPRQ-TTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLT 715
            P T +H Y     IS+LALLKM+ H R+G  +EVMGLMLG+   +  + +   FA+P  GT   V A    ++     ++  KQ GR E  +GWYHSHPG+GCWLSG+D++TQ   +Q  E  VAVVIDP +++  GKV + AFR     +   ++ P +  T  L  ++   +        + YY+L + Y K+ L++K+L  L  K W + L+
Sbjct:   44 PWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMMIMDS-FALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVTYFKSSLDRKLLELLWNKYWVNTLS 251
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Cavefish
Match: cops5 (COP9 signalosome subunit 5 [Source:NCBI gene;Acc:103038559])

HSP 1 Score: 130.568 bits (327), Expect = 7.416e-35
Identity = 82/215 (38.14%), Postives = 122/215 (56.74%), Query Frame = 2 
Query:   98 PDTAEHIY-----ISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFRLMNPNHVIANQEPRQ-TTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLT 715
            P T +H Y     IS+LALLKM+ H R+G  +EVMGLMLG+   +  + +   FA+P  GT   V A    ++     ++  KQ GR E  +GWYHSHPG+GCWLSG+D++TQ   +Q  E  VAVVIDP +++  GKV + AFR     +   ++ P +  T  L  ++   +        + YY+L + Y K+ L++K+L  L  K W + L+
Sbjct:   44 PWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMMIMDS-FALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVTYFKSSLDRKLLELLWNKYWVNTLS 251
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Cavefish
Match: brcc3 (BRCA1/BRCA2-containing complex subunit 3 [Source:NCBI gene;Acc:103031186])

HSP 1 Score: 57.7658 bits (138), Expect = 2.737e-9
Identity = 39/139 (28.06%), Postives = 65/139 (46.76%), Query Frame = 2 
Query:  116 IYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDP----VFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVV----IDPIQSVKGKVVIDAFR 508
            +++ S A L  + H  +    EVMGL +GE   +  V +  V  + +S        + P        +   + + TGRP  VVGWYHSHP    W S VD+ TQ  ++ + +  V ++    I+   +  G+V+   F+
Sbjct:    6 VHLESDAFLVCMNHALSTEKEEVMGLCIGEVDTNRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAEMTGRPVRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQ 144
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Cavefish
Match: eif3hb (eukaryotic translation initiation factor 3, subunit H, b [Source:NCBI gene;Acc:567151])

HSP 1 Score: 53.1434 bits (126), Expect = 1.558e-7
Identity = 41/134 (30.60%), Postives = 74/134 (55.22%), Query Frame = 2 
Query:  116 IYISSLALLKMLKHGRA-GVPMEVM-GLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRL 511
            I I  L +LK++KH +  G   EV+ G++LG  V D  + + + F  PQ  T    +  +  +Q +M+  L+      + VGWY S   +G ++S   +++Q S++   E +V +V DPI++ +G + + A+RL
Sbjct:   66 IQIEGLVVLKIIKHYQEEGQGSEVVQGVLLG-LVVDDRLEITNCFPFPQH-TEDDADFDEVHYQMEMMRSLRHVNIDHLHVGWYQS-TFYGSFVSRALLDSQFSYQHAIEESVVLVYDPIKTAQGSLSLKAYRL 196
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Sea Lamprey
Match: psmd14 (proteasome 26S subunit, non-ATPase 14 [Source:ZFIN;Acc:ZDB-GENE-070410-56])

HSP 1 Score: 482.256 bits (1240), Expect = 3.026e-173
Identity = 244/313 (77.96%), Postives = 271/313 (86.58%), Query Frame = 2 
Query:   23 MDQLLRIG--GFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            MD+LLR+G  G  GL Q    P+D P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+NPN ++   EPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W D L+L +Y EH   N+ T+K ML L K Y K++E+E+KMTPEQLAIKNVGK DPKRHL EHVD LM++NI Q LG+M+  +VF+
Sbjct:    1 MDRLLRLGAGGMSGLGQG--PPSDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINPNMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSISINYRKNELEQKMLLNLHKKSWMDGLSLHEYNEHCKLNESTVKEMLDLAKCYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMSSNIVQCLGAMLDTVVFK 311
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006305.1 (pep scaffold:Pmarinus_7.0:GL479573:3013:19927:-1 gene:ENSPMAG00000005669.1 transcript:ENSPMAT00000006305.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 128.257 bits (321), Expect = 1.369e-34
Identity = 81/215 (37.67%), Postives = 122/215 (56.74%), Query Frame = 2 
Query:   98 PDTAEHIY-----ISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFRLMNPNHVIANQEPRQ-TTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLT 715
            P + +H Y     +S+LALLKM+ H R+G  +EVMGLMLG+   D  + +   FA+P  GT   V A    ++     ++  KQ GR E  +GWYHSHPG+GCWLSG+D++TQ   +Q  E  VAVVIDP +++  GKV + AFR     +   ++ P +  T  L  ++   +        + YY+L + Y K+ L++K+L  L  K W + L+
Sbjct:   54 PWSKDHHYFKCCKVSALALLKMVMHARSGGNLEVMGLMLGKVDGDTMMIMDS-FALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVTYFKSSLDRKLLELLWNKYWVNTLS 261
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Sea Lamprey
Match: eif3hb (eukaryotic translation initiation factor 3, subunit H, b [Source:NCBI gene;Acc:567151])

HSP 1 Score: 50.8322 bits (120), Expect = 1.532e-7
Identity = 39/135 (28.89%), Postives = 72/135 (53.33%), Query Frame = 2 
Query:  116 IYISSLALLKMLKHGRA-GVPMEV-MGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPV-FQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRL 511
            + I  L +LK++KH +  G   +V  G++LG  V D  + + + F  PQ     S    D V +Q +M+  L+      + VGWY S   +G ++S   +++Q S++   E +V ++ DP+++  G + + A+RL
Sbjct:   28 VQIDGLVVLKIIKHCQEEGTVQDVAQGVLLG-LVVDDRLEITNCFPFPQHTEDES--DFDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TFYGSFISRALLDSQFSYQHAIEESVVLIFDPVKTALGSLSLKAYRL 158
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Yeast
Match: RPN11 (Metalloprotease subunit of 19S regulatory particle; part of 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates; involved, independent of catalytic activity, in fission of mitochondria and peroxisomes; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001900])

HSP 1 Score: 366.311 bits (939), Expect = 1.047e-127
Identity = 196/311 (63.02%), Postives = 236/311 (75.88%), Query Frame = 2 
Query:   23 MDQLLRIGGFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            M++L R+     +  S     D    DT E +YISS+ALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV VVDVFAMPQSGTGVSVEAVD VFQAKM+DMLKQTGR +MVVGWYHSHPGFGCWLS VD+NTQ+SFEQL+ RAVAVV+DPIQSVKGKVVIDAFRL++   +I N EPRQTTSN G L K +IQALIHGLNRHYYSL I Y K   E KMLMNLHK+ WQ  L + DY+E    N    K+M+ + + Y K +E+E+++T E+L  + VG+ DPK+HL E  D+ +  NI  VL + ++++  +
Sbjct:    1 MERLQRL-----MMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAATKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVLTAGVNSVAIK 306
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Yeast
Match: RRI1 (Catalytic subunit of the COP9 signalosome (CSN) complex; acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling; involved in modulation of genes controlling amino acid and lipid metabolism, and ergosterol biosynthesis [Source:SGD;Acc:S000002375])

HSP 1 Score: 83.9593 bits (206), Expect = 1.947e-18
Identity = 51/159 (32.08%), Postives = 85/159 (53.46%), Query Frame = 2 
Query:   77 APTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEA-----------VDPVFQ-AKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVV-IDAFRLM 514
            + TD P   +  H+ IS L+  K+  +   G  +E+MG+++G F     + V+D F +P  GT   V A           +D ++      D     G    VVGW+HSHPG+ CWLS +D+ TQ   ++  +  VA+V+DP++S++ K++ + AFR +
Sbjct:   61 SSTDIP---SYTHVLISKLSCEKITHYAVRGGNIEIMGILMG-FTLKDNIVVMDCFNLPVVGTETRVNAQLESYEYMVQYIDEMYNHNDGGDGRDYKGAKLNVVGWFHSHPGYDCWLSNIDIQTQDLNQRFQDPYVAIVVDPLKSLEDKILRMGAFRTI 215
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Nematostella
Match: EDO46281 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQF7])

HSP 1 Score: 488.034 bits (1255), Expect = 2.323e-175
Identity = 247/312 (79.17%), Postives = 275/312 (88.14%), Query Frame = 2 
Query:   23 MDQLLRIG--GFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVF 952
            MD++LR+G  G PG+ Q+   P+D PV DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+NPN ++  QEPRQTTSNLGHLQKPSIQA+IHGLNRHYYS+ I YRKNELEQKML+NLHKKTW D LTL DY +H + N+  +K ML LVK Y K+LEDEE MT EQLAIKNVGK DPKRHL E+VD LMT+NI Q L +M++++VF
Sbjct:    1 MDRILRLGSGGIPGVGQA--PPSDAPVVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINPNMMVLGQEPRQTTSNLGHLQKPSIQAMIHGLNRHYYSISINYRKNELEQKMLLNLHKKTWMDGLTLHDYSDHCSVNENKVKEMLDLVKNYKKALEDEETMTAEQLAIKNVGKQDPKRHLEENVDVLMTSNIVQCLSAMLNSVVF 310
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Nematostella
Match: EDO44562 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVE8])

HSP 1 Score: 131.724 bits (330), Expect = 1.182e-35
Identity = 100/303 (33.00%), Postives = 152/303 (50.17%), Query Frame = 2 
Query:   98 PDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFRLMNPNHVIANQEPRQ-TTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDD------LTLVDYKEHS----NENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKM-----DPKRHLGEHVDKLMTANISQVLGSMIHNMV 949
            P   ++I IS+LALLKM+ H R+G  +EVMGLMLG+   D  + +   FA+P  GT   V A    ++     ++  K  GR E  +GWYHSHPG+GCWLSG+D+ TQ   +Q  E  VA+VIDP +++  GKV + AFR     +   ++ P +  T  L  ++   +        + YYSL + Y K+ L++K+L  L  K W +       LT  DY  H     +E  E  ++ +  +  +   +E+           K+ GK+     D  +   E V  LM    SQV+ + + N V
Sbjct:   46 PHYFKNIKISALALLKMVMHARSGGNLEVMGLMLGKVDGDTMIVMDA-FALPVEGTETRVNAQAAAYEYMAAYIESAKSVGRLENAIGWYHSHPGYGCWLSGIDVGTQMVNQQFQEPFVAIVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYSLEVSYFKSSLDRKLLDMLWNKYWVNTLSSSSLLTNADYTNHQIADLSEKLEQAESQVGRMGTFVAGMEER----------KDEGKLAKVTRDSSKSAIEAVHGLM----SQVIKNRLFNQV 327
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Nematostella
Match: EDO35207 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM50])

HSP 1 Score: 59.3066 bits (142), Expect = 3.606e-10
Identity = 45/138 (32.61%), Postives = 65/138 (47.10%), Query Frame = 2 
Query:  134 ALLKMLKHGRAGVPMEVMGLMLGE----FXXXXXXXXXXXFAMPQSGTGVSVEAV-DPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSV---KGKVVIDAFRLMNPN 523
            AL+  L H  +    EVMGLM+GE        Y+V ++      +    +S E + D   QA+ L +L    RP  VVGWYHSHP    W S VD+ TQ  ++ + E  V V+           G + I  F+ ++ N
Sbjct:   12 ALMVCLTHALSTEREEVMGLMIGEAEDGIAHVYSVIMLQRLDKRKDRVEISPEQLSDASTQAERLGLLTPKKRPMRVVGWYHSHPHITVWPSHVDLATQAMYQVMDEGFVGVIFSCFNDEPNHTGSLTITCFQSVDVN 149
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Nematostella
Match: EDO39430 (Eukaryotic translation initiation factor 3 subunit H [Source:UniProtKB/Swiss-Prot;Acc:A7SA47])

HSP 1 Score: 51.9878 bits (123), Expect = 1.368e-7
Identity = 35/136 (25.74%), Postives = 73/136 (53.68%), Query Frame = 2 
Query:  116 IYISSLALLKMLKH----GRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRL 511
            + +  L +LK++KH    G +G    V G++LG  + D  + + + F  P +  G   +  D  +Q +++  L+      + VGWY S    G +++   +++Q S+++  E +V ++ DP+++ +G + + AFRL
Sbjct:   18 VQVDGLTVLKIIKHCEEEGSSGDL--VQGVLLG-LIQDNRLEITNCFPFPSNKAGDDEDDDDVNYQMEVMRRLRAVNIDHLHVGWYQS-TYLGSYINRTLLDSQYSYQKSIEESVVLIYDPLRTSQGMLTLKAFRL 149
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Nematostella
Match: EDO45099 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTW1])

HSP 1 Score: 49.6766 bits (117), Expect = 9.477e-7
Identity = 42/122 (34.43%), Postives = 57/122 (46.72%), Query Frame = 2 
Query:  113 HIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEA-VDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQS 475
            H+ + S AL+ M  H       EV+GL+ G +  D  V  V   A P      S++  +DPV Q +  + L   G    VVGWYHSHP F    S  D+ TQ  F++   +  A  I  I S
Sbjct:  478 HVALQSDALIVMDVHAHLST-TEVIGLLGGTYSRDNRVLQVLR-ATPCRSLSTSMQCEMDPVSQTQASEKLASKGM--AVVGWYHSHPTFAPNPSVRDIETQAKFQEWFAKGGAAFIGVIVS 595
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Medaka
Match: psmd14 (proteasome 26S subunit, non-ATPase 14 [Source:NCBI gene;Acc:101158838])

HSP 1 Score: 470.315 bits (1209), Expect = 7.066e-168
Identity = 234/291 (80.41%), Postives = 255/291 (87.63%), Query Frame = 2 
Query:   83 TDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            TD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+N N ++   EPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W + LTL DY EH   N+  +K ML L K Y K++E+E+KMTPEQLAIKNVGK DPKRHL EHVD LMT+NI Q L +M+  +VFQ
Sbjct:   20 TDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKLNETIVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFQ 310
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Medaka
Match: psmd14 (proteasome 26S subunit, non-ATPase 14 [Source:NCBI gene;Acc:101158838])

HSP 1 Score: 428.328 bits (1100), Expect = 5.562e-151
Identity = 213/258 (82.56%), Postives = 230/258 (89.15%), Query Frame = 2 
Query:   83 TDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGK 856
            TD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+N N ++   EPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELEQKML+NLHKK+W + LTL DY EH   N+  +K ML L K Y K++E+E+KMTPEQLAIKNVGK
Sbjct:   59 TDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKLNETIVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGK 316
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Medaka
Match: psmd14 (proteasome 26S subunit, non-ATPase 14 [Source:NCBI gene;Acc:101158838])

HSP 1 Score: 421.009 bits (1081), Expect = 2.930e-148
Identity = 221/297 (74.41%), Postives = 242/297 (81.48%), Query Frame = 2 
Query:   83 TDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQK---MLMNLHKKTWQDDLTLVDYKEHSNENKETLKAML---SLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            TD P  DTAE +YISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVD+NTQQSFE LSERAVAVV+DPIQSVKGKVVIDAFRL+N N ++   EPRQTTSNLGHL KPSIQALIHGLNRHYYS+ I YRKNELEQK   +L NL    + D   L      S+     L  ML   + V    +++E+E+KMTPEQLAIKNVGK DPKRHL EHVD LMT+NI Q L +M+  +VFQ
Sbjct:   20 TDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKASLLLSNLIPFCFMDSQQLQTALSSSSSTPCFLFMMLPDTNFVTFSFQAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFQ 316
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Medaka
Match: cops5 (COP9 signalosome subunit 5 [Source:NCBI gene;Acc:101155235])

HSP 1 Score: 129.028 bits (323), Expect = 2.725e-34
Identity = 81/210 (38.57%), Postives = 119/210 (56.67%), Query Frame = 2 
Query:   98 PDTAEHIY-----ISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVK-GKVVIDAFRLMNPNHVIANQEPRQ-TTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTW 700
            P T +H Y     IS+LALLKM+ H R+G  +EVMGLMLG+   +  + +   FA+P  GT   V A    ++     ++  KQ GR E  +GWYHSHPG+GCWLSG+D++TQ   +Q  E  VAVVIDP +++  GKV + AFR     +   ++ P +  T  L  ++   +        + YY+L + Y K+ L++K+L  L  K W
Sbjct:   42 PWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDS-FALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVTYFKSSLDRKLLELLWNKYW 244
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Medaka
Match: brcc3 (BRCA1/BRCA2-containing complex, subunit 3 [Source:ZFIN;Acc:ZDB-GENE-100215-1])

HSP 1 Score: 56.6102 bits (135), Expect = 1.053e-8
Identity = 42/148 (28.38%), Postives = 68/148 (45.95%), Query Frame = 2 
Query:  116 IYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAM-------------PQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVV----IDPIQSVKGKVVIDAFR 508
            +++ S A L  + H  +    EVMGL +GE  +   V +  V  +             P+  +  S EA       ++ D+   TG+P  VVGWYHSHP    W S VD+ TQ  ++ L +  V ++    I+   +  G+V+   F+
Sbjct:   42 VHLESDAFLVCMNHALSTEKEEVMGLCIGEVEEARIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEA------ERLADL---TGKPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMLDQGFVGLIFSCFIEDKNTRTGRVLYTCFQ 180
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Planmine SMEST
Match: SMESG000056198.1 (SMESG000056198.1)

HSP 1 Score: 621.313 bits (1601), Expect = 0.000e+0
Identity = 311/311 (100.00%), Postives = 311/311 (100.00%), Query Frame = 2 
Query:   23 MDQLLRIGGFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            MDQLLRIGGFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ
Sbjct:    1 MDQLLRIGGFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 311
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Planmine SMEST
Match: SMESG000056298.1 (SMESG000056298.1)

HSP 1 Score: 573.163 bits (1476), Expect = 0.000e+0
Identity = 293/311 (94.21%), Postives = 293/311 (94.21%), Query Frame = 2 
Query:   23 MDQLLRIGGFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 955
            MDQLLRIGGFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQK                  YKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ
Sbjct:    1 MDQLLRIGGFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKY-----------------YKEHSNENKETLKAMLSLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQVLGSMIHNMVFQ 294
[Close]
BLAST of 26S proteasome regulatory subunit N11 vs. Planmine SMEST
Match: SMESG000038057.1 (SMESG000038057.1)

HSP 1 Score: 119.783 bits (299), Expect = 4.193e-31
Identity = 70/201 (34.83%), Postives = 112/201 (55.72%), Query Frame = 2 
Query:  110 EHIYISSLALLKMLKHGRAGVPMEVMGLMLGEFXXXXXXXXXXXFAMPQSGTGVSVEAVDPVFQAKML--DMLKQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQSV-KGKVVIDAFRLMNPNHVIANQEPRQTTS-NLGHLQKPSIQALIHGLNRHYYSLPIGYRKNELEQKMLMNLHKKTW 700
            ++I +S+ ALLKM+ H R G  +EVMG++ G+   +  + +    A+P  GT   V A    ++   +  D + + GR E V+GWYHSHPG+GCWLSG+D+ TQ   +   +  VAVV+DP+++V  GKV I AFR    ++   +Q P +  S  L  ++   +        + YY L + Y K+ L++ +L  L  + W
Sbjct:   45 KYIRVSAHALLKMVTHARRGGNLEVMGMLFGKVTHNTMIVMDS-VALPVEGTETRVNAQSEAYEFITMYKDTVAKIGRTENVIGWYHSHPGYGCWLSGIDVTTQTMNQTYQDPFVAVVLDPVRTVSSGKVNIGAFRTYPRHYSPPDQGPSEYQSIPLNKIEDFGVHC------KQYYPLVMSYFKSSLDKSILDILWNRYW 238
The following BLAST results are available for this feature:
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PSMD142.159e-16780.07proteasome 26S subunit, non-ATPase 14 [Source:HGNC... [more]
COPS51.281e-3438.14COP9 signalosome subunit 5 [Source:HGNC Symbol;Acc... [more]
COPS51.309e-3036.60COP9 signalosome subunit 5 [Source:HGNC Symbol;Acc... [more]
PSMD141.555e-2589.23proteasome 26S subunit, non-ATPase 14 [Source:HGNC... [more]
COPS55.492e-2545.16COP9 signalosome subunit 5 [Source:HGNC Symbol;Acc... [more]
back to top
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
rpn-119.119e-15675.0026S proteasome non-ATPase regulatory subunit 14 [... [more]
F37A4.51.339e-10253.29pep chromosome:WBcel235:III:6711869:6713191:1 gene... [more]
csn-54.850e-3234.70COP9 signalosome complex subunit 5 [Source:UniPro... [more]
back to top
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Rpn114.841e-17779.74gene:FBgn0028694 transcript:FBtr0079027[more]
CSN54.612e-3838.76gene:FBgn0027053 transcript:FBtr0334535[more]
CSN55.407e-3838.76gene:FBgn0027053 transcript:FBtr0083292[more]
back to top
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
psmd141.222e-17278.78proteasome 26S subunit, non-ATPase 14 [Source:ZFIN... [more]
cops51.412e-3437.67COP9 signalosome subunit 5 [Source:NCBI gene;Acc:3... [more]
brcc33.527e-1028.37BRCA1/BRCA2-containing complex, subunit 3 [Source:... [more]
eif3ha9.283e-1030.00eukaryotic translation initiation factor 3, subuni... [more]
brcc32.968e-928.06BRCA1/BRCA2-containing complex, subunit 3 [Source:... [more]
back to top
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prokr23.688e-16779.79prokineticin receptor 2 [Source:Xenbase;Acc:XB-GEN... [more]
prokr27.034e-16779.79prokineticin receptor 2 [Source:Xenbase;Acc:XB-GEN... [more]
prokr21.972e-16679.73prokineticin receptor 2 [Source:Xenbase;Acc:XB-GEN... [more]
prokr21.533e-14272.16prokineticin receptor 2 [Source:Xenbase;Acc:XB-GEN... [more]
cops52.511e-3437.67COP9 signalosome subunit 5 [Source:NCBI gene;Acc:3... [more]
back to top
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Psmd141.482e-16780.07proteasome (prosome, macropain) 26S subunit, non-A... [more]
Cops57.524e-3538.14COP9 signalosome subunit 5 [Source:MGI Symbol;Acc:... [more]
Cops59.280e-3044.30COP9 signalosome subunit 5 [Source:MGI Symbol;Acc:... [more]
Cops58.429e-2850.78COP9 signalosome subunit 5 [Source:MGI Symbol;Acc:... [more]
Brcc33.597e-928.99BRCA1/BRCA2-containing complex, subunit 3 [Source:... [more]
back to top
BLAST of 26S proteasome regulatory subunit N11 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9V3H2|PSDE_DROME4.852e-17679.7426S proteasome non-ATPase regulatory subunit 14 OS... [more]
sp|O35593|PSDE_MOUSE1.037e-16680.0726S proteasome non-ATPase regulatory subunit 14 OS... [more]
sp|O00487|PSDE_HUMAN1.037e-16680.0726S proteasome non-ATPase regulatory subunit 14 OS... [more]
sp|Q9LT08|PSDE_ARATH1.086e-15471.2926S proteasome non-ATPase regulatory subunit 14 ho... [more]
sp|O76577|PSDE_CAEEL1.160e-15475.0026S proteasome non-ATPase regulatory subunit 14 OS... [more]
back to top
BLAST of 26S proteasome regulatory subunit N11 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A183L3270.000e+083.65MPN domain-containing protein OS=Schistosoma curas... [more]
O161540.000e+083.65Pad1 homolog OS=Schistosoma mansoni OX=6183 GN=SmP... [more]
C1L5Q30.000e+083.6526S proteasome non-ATPase regulatory subunit 14 OS... [more]
Q5DI410.000e+083.65SJCHGC06520 protein OS=Schistosoma japonicum OX=61... [more]
C1L5Q10.000e+083.3326S proteasome regulatory subunit N11 OS=Schistoso... [more]
back to top
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
psmd148.659e-16880.41proteasome 26S subunit, non-ATPase 14 [Source:NCBI... [more]
cops55.566e-3538.14COP9 signalosome subunit 5 [Source:NCBI gene;Acc:1... [more]
cops57.416e-3538.14COP9 signalosome subunit 5 [Source:NCBI gene;Acc:1... [more]
brcc32.737e-928.06BRCA1/BRCA2-containing complex subunit 3 [Source:N... [more]
eif3hb1.558e-730.60eukaryotic translation initiation factor 3, subuni... [more]
back to top
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
psmd143.026e-17377.96proteasome 26S subunit, non-ATPase 14 [Source:ZFIN... [more]
ENSPMAT00000006305.11.369e-3437.67pep scaffold:Pmarinus_7.0:GL479573:3013:19927:-1 g... [more]
eif3hb1.532e-728.89eukaryotic translation initiation factor 3, subuni... [more]
back to top
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
RPN111.047e-12763.02Metalloprotease subunit of 19S regulatory particle... [more]
RRI11.947e-1832.08Catalytic subunit of the COP9 signalosome (CSN) co... [more]
back to top
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO462812.323e-17579.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO445621.182e-3533.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO352073.606e-1032.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO394301.368e-725.74Eukaryotic translation initiation factor 3 subunit... [more]
EDO450999.477e-734.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of 26S proteasome regulatory subunit N11 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
psmd147.066e-16880.41proteasome 26S subunit, non-ATPase 14 [Source:NCBI... [more]
psmd145.562e-15182.56proteasome 26S subunit, non-ATPase 14 [Source:NCBI... [more]
psmd142.930e-14874.41proteasome 26S subunit, non-ATPase 14 [Source:NCBI... [more]
cops52.725e-3438.57COP9 signalosome subunit 5 [Source:NCBI gene;Acc:1... [more]
brcc31.053e-828.38BRCA1/BRCA2-containing complex, subunit 3 [Source:... [more]
back to top
BLAST of 26S proteasome regulatory subunit N11 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000056198.10.000e+0100.00SMESG000056198.1[more]
SMESG000056298.10.000e+094.21SMESG000056298.1[more]
SMESG000038057.14.193e-3134.83SMESG000038057.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002574 ID=SMED30002574|Name=26S proteasome regulatory subunit N11|organism=Schmidtea mediterranea sexual|type=transcript|length=1018bp
ATCTATATAAATCTTATATGAGATGGATCAATTATTAAGAATTGGTGGTT
TTCCTGGATTAAGACAATCAAACAGTGCACCTACTGATGGGCCTGTCCCA
GATACTGCCGAACATATTTATATCAGTTCGTTAGCATTATTAAAAATGTT
AAAGCATGGTCGAGCAGGTGTACCTATGGAAGTTATGGGATTGATGCTGG
GAGAATTTGTAGATGATTACACAGTGACTGTAGTTGATGTTTTCGCTATG
CCACAATCTGGTACTGGAGTCAGTGTTGAAGCAGTAGATCCAGTTTTTCA
AGCTAAAATGTTGGATATGCTTAAACAAACTGGTAGACCTGAAATGGTTG
TAGGCTGGTATCATTCCCATCCTGGCTTTGGTTGTTGGTTATCAGGTGTT
GATATGAATACCCAACAAAGCTTTGAACAGCTATCAGAACGAGCAGTTGC
TGTTGTCATAGATCCAATCCAAAGTGTAAAAGGAAAAGTTGTGATTGATG
CTTTCCGTTTAATGAACCCCAATCATGTTATTGCCAATCAAGAACCAAGA
CAAACGACTTCAAATTTAGGTCATTTACAAAAGCCTTCAATCCAGGCTCT
CATTCACGGATTAAATAGGCATTACTATTCATTGCCTATAGGCTATAGGA
AAAATGAATTAGAACAAAAAATGTTAATGAATTTGCACAAGAAAACATGG
CAGGATGATCTAACACTTGTAGATTATAAAGAACATTCTAATGAAAATAA
AGAAACTTTAAAAGCAATGTTATCTTTAGTTAAAGCATATTGTAAATCTT
TGGAAGATGAAGAAAAGATGACTCCAGAGCAATTAGCAATAAAAAATGTT
GGAAAAATGGATCCAAAACGTCATTTGGGAGAGCATGTAGATAAATTAAT
GACAGCAAATATTAGTCAAGTTCTTGGTTCAATGATTCACAATATGGTTT
TTCAATAACTTCAATTTATGTAATTTGTTTTGGTTCGTATTAAAACAAAT
AAAGTGCTCATAGCAGTT
back to top

protein sequence of SMED30002574-orf-1

>SMED30002574-orf-1 ID=SMED30002574-orf-1|Name=SMED30002574-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=312bp
MDQLLRIGGFPGLRQSNSAPTDGPVPDTAEHIYISSLALLKMLKHGRAGV
PMEVMGLMLGEFVDDYTVTVVDVFAMPQSGTGVSVEAVDPVFQAKMLDML
KQTGRPEMVVGWYHSHPGFGCWLSGVDMNTQQSFEQLSERAVAVVIDPIQ
SVKGKVVIDAFRLMNPNHVIANQEPRQTTSNLGHLQKPSIQALIHGLNRH
YYSLPIGYRKNELEQKMLMNLHKKTWQDDLTLVDYKEHSNENKETLKAML
SLVKAYCKSLEDEEKMTPEQLAIKNVGKMDPKRHLGEHVDKLMTANISQV
LGSMIHNMVFQ*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
GO:0070536protein K63-linked deubiquitination
Vocabulary: molecular function
TermDefinition
GO:0008237metallopeptidase activity
GO:0061578Lys63-specific deubiquitinase activity
GO:0005515protein binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000429neoblast
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR035299PSMD14
IPR037518MPN
IPR000555JAMM/MPN+_dom
IPR024969Rpn11/EIF3F_C
Vocabulary: cellular component
TermDefinition
GO:0000502proteasome complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000555JAB1/MPN/MOV34 metalloenzyme domainSMARTSM00232pad1_6coord: 34..169
e-value: 9.1E-45
score: 164.7
IPR000555JAB1/MPN/MOV34 metalloenzyme domainPFAMPF01398JABcoord: 32..142
e-value: 4.5E-32
score: 110.5
IPR024969Rpn11/EIF3F, C-terminalPFAMPF13012MitMem_regcoord: 177..304
e-value: 1.0E-14
score: 54.9
NoneNo IPR availableGENE3DG3DSA:3.40.140.10coord: 17..236
e-value: 6.9E-74
score: 250.3
NoneNo IPR availablePANTHERPTHR10410EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATEDcoord: 23..309
NoneNo IPR availableCDDcd08069MPN_RPN11_CSN5coord: 25..290
e-value: 3.51504E-150
score: 420.121
NoneNo IPR availableSUPERFAMILYSSF102712JAB1/MPN domaincoord: 35..171
IPR03529926S Proteasome non-ATPase regulatory subunit 14PANTHERPTHR10410:SF22coord: 23..309
IPR037518MPN domainPROSITEPS50249MPNcoord: 35..170
score: 36.293