ATP-binding cassette sub-family D member 2

Overview
NameATP-binding cassette sub-family D member 2
Smed IDSMED30002568
Length (bp)2297
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of ATP-binding cassette sub-family D member 2 (SMED30002568) t-SNE clustered cells

Violin plots show distribution of expression levels for ATP-binding cassette sub-family D member 2 (SMED30002568) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ATP-binding cassette sub-family D member 2 (SMED30002568) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ATP-binding cassette sub-family D member 2 (SMED30002568) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30002568

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30002568h1SMcG0001092 Contig2577GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30002568h1SMcG0001092 dd_Smed_v4_3611_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30002568h1SMcG0001092 dd_Smed_v4_3611_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Human
Match: ABCD1 (ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61])

HSP 1 Score: 659.833 bits (1701), Expect = 0.000e+0
Identity = 322/602 (53.49%), Postives = 436/602 (72.43%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATG-RRNDGSFV-----DDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYR--------------VTNNAIEYQG----QSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            E+ LL +H+  L+ RTFLS+YVA LDG++ R IV++D   F  QLL++LLIALPATF+NS IR+LE +L++ FR++LV + Y+LYF  QTYYRV N+D R++N DQSLTED+  F++S+AHLYS LTKP LD+ + S++L + AR+RGA    P  IA  VV  T   LR  SPKFG LVAEEA+ KG LR++HSR++ NSEEIAFY GHEVE  +L ++YQ+L  Q N I L++LWYVM+EQFLMKYVWS++G+ MV++PI+TATG   +D   V     +   +  VSERT+ FT+ARNLL  +A A+ER+++SYKEVTEL+GYT+RVHE+  VF D+ +  ++              +  + +  +G    +  V  ++  +   N      +PIVTP+G+VVV  L++R+ +G H+LITGPNGCGKSSLFRI  GLWP YGG L  PP   M++IPQ+PY+ +G+LRDQ+IYPD++  M+ KG +++DL+ ILD+V L  I+ REGG +   DW +V SGGEKQRIGMAR+FYH+P++ALLDECTSAVSIDVE  I++ A   G+ LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   90 ETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFGWQLLQWLLIALPATFVNSAIRYLEGQLALSFRSRLVAHAYRLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQRSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYSESDAEAVKKAALEKKEEELVSERTEAFTIARNLLTAAADAIERIMSSYKEVTELAGYTARVHEMFQVFEDVQRCHFKRPRELEDAQAGSGTIGRSGVRVEGPLKIRGQVVDVEQGIICEN------IPIVTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYGGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHHILQREGGWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLD 685          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Human
Match: ABCD2 (ATP binding cassette subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:66])

HSP 1 Score: 657.907 bits (1696), Expect = 0.000e+0
Identity = 344/623 (55.22%), Postives = 454/623 (72.87%), Query Frame = 2
Query:  248 ENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGG----VSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQS-NVAKLDDAVPATNYIE-----------LIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            E     VN+ FF++L  L KI+FPK ++ E+  LC+H+  L+ RTFLSIYVAGLDGKIV+SIV++    F+I+L+K+L+IA+PATF+NS IR+LE +L++ FRT+LV++ Y+ YF +QTYY+V N+D R+ N DQSLTEDI +FS S+AHLYS LTKP LD+ L S++L + A +RGAS   P ++A  VV +T + L+  SPKFG LVAEEA  KGYLR+VHSRII N EEIAFY GH+VE   L K+Y+ L  Q N I  ++LWY+MIEQFLMKYVWSS+G+ MV+IPI+TATG      F D + DG     VSERT+ FT ARNLL + A A+ER+++SYKEVTEL+GYT+RV+ +  VF ++ + +Y+ T    E +  S N AK++  +  T  I+              VPI+TP G+VV   L+ ++ +G H+LITGPNGCGKSSLFRI  GLWP+Y G L  PP   M++IPQ+PY+ LG+LRDQ+IYPD++  M +KG TD+DL+ IL  V L  I+ REGG D   DW +V SGGEKQR+GMAR+FYHKP++ALLDECTSAVSIDVE  I++ A   G++LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   74 EKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSYTLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMVAIPIITATG------FADGE-DGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLD 689          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Human
Match: ABCD3 (ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67])

HSP 1 Score: 427.172 bits (1097), Expect = 2.117e-139
Identity = 242/622 (38.91%), Postives = 368/622 (59.16%), Query Frame = 2
Query:  248 ENEGSK----VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKL------DDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDEIK 2083
            E EG K    V+ +FF RL  +LKI+ P+   KE+  L +    L+ RT+  +++      I   I+ R+   F     KF+      + +N+F+++    L +CFR +L +Y Y+ Y +  TYY++ N+D RI N DQ LT+D+  F +S+  LYS L+KPFLD+ L  F L      +G     P  + A +V+S G FL  +    G +   E K++G  R+V+SR+I NSEEIAFY+G++ E   +   +++L++  +   L +     I+  + KY+ +  G  +VS P L  +  R+  S          SE  + +  +  +L   + A+ R++ + +E+T L+G+T+R+ EL+ V  DL+   Y  T  + + +G   V  +       + + A N I+   VP+ TPNGDV++ +L+  +  G ++LI GPNGCGKSSLFR+   LWP++GG+LT P +  ++++PQ+PY+ LGTLRDQ+IYPD     K KG++D  L+E LD VQL  I+ REGG D  +DW++V SGGEKQR+ MARLFYHKPQFA+LDECTSAVS+DVE  IY    K+G+TL TV+HR SLWK H   L  DG G +    + +D ++
Sbjct:   49 EKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIISRNKALFKKPFFKFIAATPMISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQG-----PASMMAYLVVS-GLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKS--------THSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVE 656          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Human
Match: ABCD3 (ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67])

HSP 1 Score: 425.631 bits (1093), Expect = 8.248e-139
Identity = 242/624 (38.78%), Postives = 369/624 (59.13%), Query Frame = 2
Query:  230 NEMKTLENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKL------DDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDEIK 2083
            N  K  + E + V+ +FF RL  +LKI+ P+   KE+  L +    L+ RT+  +++      I   I+ R    F   LL F+      + +N+F+++    L +CFR +L +Y Y+ Y +  TYY++ N+D RI N DQ LT+D+  F +S+  LYS L+KPFLD+ L  F L      +G     P  + A +V+S G FL  +    G +   E K++G  R+V+SR+I NSEEIAFY+G++ E   +   +++L++  +   L +     I+  + KY+ +  G  +VS P L  +  R+  S          SE  + +  +  +L   + A+ R++ + +E+T L+G+T+R+ EL+ V  DL+   Y  T  + + +G   V  +       + + A N I+   VP+ TPNGDV++ +L+  +  G ++LI GPNGCGKSSLFR+   LWP++GG+LT P +  ++++PQ+PY+ LGTLRDQ+IYPD     K KG++D  L+E LD VQL  I+ REGG D  +DW++V SGGEKQR+ MARLFYHKPQFA+LDECTSAVS+DVE  IY    K+G+TL TV+HR SLWK H   L  DG G +    + +D ++
Sbjct:   47 NNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQG-----PASMMAYLVVS-GLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKS--------THSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVE 656          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Human
Match: ABCD1 (ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61])

HSP 1 Score: 222.631 bits (566), Expect = 4.657e-67
Identity = 102/176 (57.95%), Postives = 133/176 (75.57%), Query Frame = 2
Query:  623 IDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDG 1150
            +D R++N DQSLTED+  F++S+AHLYS LTKP LD+ + S++L + AR+RGA    P  IA  VV  T   LR  SPKFG LVAEEA+ KG LR++HSR++ NSEEIAFY GHEVE  +L ++YQ+L  Q N I L++LWYVM+EQFLMKYVWS++G+ MV++PI+TATG    G
Sbjct:    1 MDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQRSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYSESG 176          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Celegans
Match: pmp-4 (Peroxisomal Membrane Protein related [Source:UniProtKB/TrEMBL;Acc:O45730])

HSP 1 Score: 652.514 bits (1682), Expect = 0.000e+0
Identity = 329/593 (55.48%), Postives = 440/593 (74.20%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLA--RNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRND--GSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVY-RVTNNAIEYQGQS----NVAKLDDAVPATNYIELI--KVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDEI 2080
            E+ ++ +H+  L+ RTFL+I+VA L+G +V++IV+++V +F++ L+K++L+ALPATF+NS IRF E  L + FRT+L ++ YK YF  QTYY V N+D R++N DQ LTEDI++FS S+AHLYS LTKP LD+ L++F+L KLA  R  G S  +P  +A   V  T + LR +SP+FG +VAEEA+ KG+LR++HSRII NSEEIAFY GH+ E   L  A+  L +Q   I  +++ Y+MIEQFLMKYVWS TGM M+++PIL AT   +D   + ++D PD GVSERT+ +  A+ LL NSA AVER++TSYKEVTEL+GYT RVHE+  VF D  + +Y R T +A   QGQ     + +K++  +  +   E+I   VPIVTPNGDVVV  ++L I+ G H+LITGPNGCGKSSLFRI  GLWP+Y G L  P  + MY+IPQ+PY+ LGTLRDQ+IYPD  IQM+ +G+TD+DL  +L IV LE I+ REGG D + DW++V SGGEKQR+GMAR+FYH+P++ALLDECTSAVSIDVE +IY+     G+TLLTVTHRPSLWKFH  LL++DGEGG+ +S+L +  I
Sbjct:   92 EAGIIGMHSIILICRTFLTIFVAQLEGSMVQAIVEKNVLQFVLHLVKWILVALPATFVNSMIRFFESYLGLAFRTRLTKHAYKQYFSDQTYYAVSNLDTRLQNADQCLTEDITMFSQSVAHLYSHLTKPVLDVALITFTLIKLAIQRGTGRSTFLPSCMAIMAVSLTAKILRAVSPRFGHMVAEEARRKGHLRYLHSRIITNSEEIAFYGGHQAEYKQLDGAFNSLYQQMMLIFKKRIPYIMIEQFLMKYVWSGTGMVMIALPIL-ATEYADDEKSTKLEDLPDRGVSERTRGYATAKTLLFNSADAVERLMTSYKEVTELAGYTGRVHEMFQVFDDAKKGIYQRQTVSAGAEQGQRGERFDTSKIEGIITDSEADEIILNSVPIVTPNGDVVVKNMTLTISPGMHVLITGPNGCGKSSLFRILGGLWPVYRGHLEKPTSDRMYYIPQRPYMTLGTLRDQVIYPDTTIQMRRQGITDQDLMTMLRIVHLEHIVEREGGWDAQNDWMDVLSGGEKQRMGMARVFYHRPKYALLDECTSAVSIDVEGSIYQAIKDSGITLLTVTHRPSLWKFHTHLLQYDGEGGYKVSSLNEKTI 683          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Celegans
Match: pmp-2 (Peroxisomal Membrane Protein related [Source:UniProtKB/TrEMBL;Acc:Q18598])

HSP 1 Score: 404.06 bits (1037), Expect = 7.066e-131
Identity = 229/590 (38.81%), Postives = 341/590 (57.80%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDD--PDGGVSERTQIFTMARN---LLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPAT-------NYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            ESF L +    L+ RT+  +Y+     KI  SI+ R+   F ++  K++L     +  N+ ++F    L + FR +L  + Y  Y K  T+Y++ N+D RI+N DQ LT+D+  F   +  LYS L+KP LD+ L    L++L  + G S   P I+ +  ++ TG  L  +    G L  EE   +G  R+V+SR+I NSEEIAFY G++ E   +M  +  L++   +I L +     ++  + KY+ +  G + V              SF D    P  G+S R Q+     N   ++   A A+ R+  + +++T LSG+TSRV  LL V  D++   Y+ T   +  + +S+     + V  +       N I    VP+VTPNGDV++  L+  +  G ++L+ GPNGCGKSSLFR+   LWP++GG LT P K  ++++PQ+PY+ LGTLRDQIIYPD  + M  KG++D DL+++L+ VQL  I+ REGG    +DW++V SGGEKQRI MARLFYHKPQFA+LDECTSAVS+DVE  +Y    +  +TL TV+HR SLWK+H   L  DG G +    ++
Sbjct:   85 ESFYLILIAVSLLCRTYADVYMIITSTKIEASIIDRNPLLFALEAFKYVLNLPAISVTNAILKFGIAELKLRFRERLSTHLYSQYLKGFTFYKMSNLDTRIQNADQLLTQDVDRFCDGIVELYSNLSKPILDVFLY---LFRLGTSLGFSS--PSILFS-YLLFTGVGLTYLRRPIGRLTVEEQALEGEYRYVNSRLIMNSEEIAFYQGNQSEKETIMSTFASLVQHLRKIILFRFSIGFVDNIVAKYLATVVGWYAVG------------SSFFDKQHKPFIGMS-RNQLMQEYYNSGRMMYKMAEALGRLALAGRDMTRLSGFTSRVDTLLNVLDDVNSGNYKRT--MVGEKEESSALIKSELVAGSGNLRVQDNVIRFDNVPLVTPNGDVLIERLNFEVPSGTNVLVCGPNGCGKSSLFRVLGELWPLFGGTLTKPAKGKLFYVPQRPYMTLGTLRDQIIYPDRPLDMIRKGVSDSDLEQMLENVQLTHILEREGGWSAVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGAMYRLCREKNITLFTVSHRKSLWKYHEYSLYMDGRGSYRFEQID 653          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Celegans
Match: pmp-1 (Peroxisomal Membrane Protein related [Source:UniProtKB/TrEMBL;Acc:Q18597])

HSP 1 Score: 404.06 bits (1037), Expect = 7.930e-131
Identity = 225/582 (38.66%), Postives = 332/582 (57.04%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEY--QGQSNVAKLDDA--VPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            E F + V  F L+ RT   +Y+      +  SIV R    F + + K+ L     + IN+ ++F    L + FR  L +Y Y  Y    TYY++ N+D RI+N DQ LT+D+  F   +  LYS +TKP LD+ L  F L +     G  +    ++A+ VV++     +L  P    L  EE   +G  R+V+SR+I NSEEIAFY G++ E   LM ++  L+    +  + +     ++  + KY+ +  G    +          N+  F + D +  + E   ++   R +L  S  A+ R+  + +++T LSG+T+RV  L+ V  D+    +     A E   +GQ  + K      +   N I+  +VP+VTPNGD+++  LS  +  G ++L+ GPNGCGKSSLFR    LWP+ GG LT P K  ++++PQ+PY+ LGTLRDQ+IYPD    MK KGM+DKDL+++L+ VQL  I+ REGG    +DW++V SGGEKQRI MARLFYHKPQFA+LDECTSAVS+DVE  +Y    +M +TL TV+HR SLWK+H   L  DG G +    ++
Sbjct:   90 EVFYMIVIGFVLLARTIADVYMITNATSVEASIVDRSPIMFAMSVFKYFLNLPAISLINALLKFSLSELKLRFRENLTKYLYGKYLGGFTYYQISNLDSRIQNPDQLLTQDVEKFCDGIVELYSNMTKPILDVFLYVFKLGRALGWEGPGLLFGYLMASMVVLT-----KLRRP-IAKLTVEEQVLEGEYRYVNSRLIMNSEEIAFYQGNKPEKQALMGSFNNLVYHLRKTIMFRFTLGFVDNIVGKYITNIVGWVACAKTFFDV----NNEKFNEMDRNELMQE---LYNNGRMMLKLS-EALGRLALAGRDMTRLSGFTTRVDTLMKVLDDMKAGRFEKAQVADESGEEGQRLMLKAGSGKLLAQDNMIKFDEVPLVTPNGDILIESLSFEVPSGRNVLVCGPNGCGKSSLFRTLGELWPVMGGTLTKPAKGKLFYVPQRPYMTLGTLRDQVIYPDTSFDMKMKGMSDKDLEQMLENVQLTNILEREGGWSAVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGAMYRLCREMNITLFTVSHRKSLWKYHEYSLYMDGRGSYRFEQID 657          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Celegans
Match: pmp-3 (Peroxisomal Membrane Protein related [Source:UniProtKB/TrEMBL;Acc:F5GUC6])

HSP 1 Score: 169.859 bits (429), Expect = 3.840e-44
Identity = 158/588 (26.87%), Postives = 264/588 (44.90%), Query Frame = 2
Query:  500 TFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAH--LYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQF--LMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDL--------------SQSVYRVTNNAIEYQGQSNVAKL---------------------------DDAVPATNYIELIKVPIVTPNGD---VVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPK---NTMYHIPQKPYLFLG--TLRDQIIYPDNLIQMKNKGMTDKD---LQEILDIVQLEPIITREGGLD--VEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGG-WNLSNLEKDEIKN 2086
             F  +  ++L   L+I  R       ++LYFK Q ++++ +    + N DQ LT+DI   +  L++  L    T PF+         Y       +    P  I     I T     ++SP     V+E+ K +G  R  H  +  N E IAFY    +E+ +  +  + LI+    ++    W +++     +  Y        ++ +P+   T   +D S  + +   G+  R   F +    L  S S V ++   + E   L+G T RV EL      L                SV  + ++  +     ++ ++                           +D  P       +    ++P  D   ++V  LSL+I +G  +LITG +GCGKSSL R+F GLW    GK+    +   + ++ + QKPY   G  TLR QI+YP   +Q+      DKD   + +IL+ V++E ++ R GGLD  VE DW+   S GE QR+ +AR+FY KP+   LDE TSA+  ++E  IY    +  +T +++ HR SL +FH++ L+  G  G W+L +++   I +
Sbjct:   85 AFTLAVFKYLTNMLAIKSRQVCNLTMHRLYFKRQAFFKLSSSGDMLDNPDQRLTQDIEKATRILSNDLLAPIATAPFI------IGYYTWLTYESSGWIGPAAIYTYFCIQTIINKMILSPIVQK-VSEQEKMEGDFRQRHMEVRSNVEAIAFYRAGVLENIMTNQKLKNLIETQKSLTE---WRMVLNSITNVFDYFGGILSYLIIGVPVFI-THLYDDVSPAELN---GIVSRNAFFYL---YLIYSFSTVLKLTGDFGE---LAGVTHRVMELHEELNRLHSDCLETDRPPSTVPSSVVVIASDEDDKSASRHMQEIHGKQMSLERDEQEEEEAQYLLGGKTGQEDDWPDDGVAITVDSATLSPPNDHSHLIVQLLSLQIIQGQTLLITGDSGCGKSSLLRMFAGLWHCSSGKMDCHWRRLTSNLFFLAQKPYFPSGNTTLRQQIVYPVKALQV------DKDVARITQILEWVKMEHLVERCGGLDTPVEWDWMKTLSPGELQRLSLARVFYTKPRIVFLDESTSAIGFELEMAIYRKLQEEKITFVSIGHRYSLKQFHDMELRVKGRSGEWSLHDIDTASIAS 646          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Celegans
Match: pmp-3 (Peroxisomal Membrane Protein related [Source:UniProtKB/TrEMBL;Acc:F5GUC6])

HSP 1 Score: 169.474 bits (428), Expect = 5.597e-44
Identity = 158/588 (26.87%), Postives = 264/588 (44.90%), Query Frame = 2
Query:  500 TFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAH--LYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQF--LMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDL--------------SQSVYRVTNNAIEYQGQSNVAKL---------------------------DDAVPATNYIELIKVPIVTPNGD---VVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPK---NTMYHIPQKPYLFLG--TLRDQIIYPDNLIQMKNKGMTDKD---LQEILDIVQLEPIITREGGLD--VEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGG-WNLSNLEKDEIKN 2086
             F  +  ++L   L+I  R       ++LYFK Q ++++ +    + N DQ LT+DI   +  L++  L    T PF+         Y       +    P  I     I T     ++SP     V+E+ K +G  R  H  +  N E IAFY    +E+ +  +  + LI+    ++    W +++     +  Y        ++ +P+   T   +D S  + +   G+  R   F +    L  S S V ++   + E   L+G T RV EL      L                SV  + ++  +     ++ ++                           +D  P       +    ++P  D   ++V  LSL+I +G  +LITG +GCGKSSL R+F GLW    GK+    +   + ++ + QKPY   G  TLR QI+YP   +Q+      DKD   + +IL+ V++E ++ R GGLD  VE DW+   S GE QR+ +AR+FY KP+   LDE TSA+  ++E  IY    +  +T +++ HR SL +FH++ L+  G  G W+L +++   I +
Sbjct:  113 AFTLAVFKYLTNMLAIKSRQVCNLTMHRLYFKRQAFFKLSSSGDMLDNPDQRLTQDIEKATRILSNDLLAPIATAPFI------IGYYTWLTYESSGWIGPAAIYTYFCIQTIINKMILSPIVQK-VSEQEKMEGDFRQRHMEVRSNVEAIAFYRAGVLENIMTNQKLKNLIETQKSLTE---WRMVLNSITNVFDYFGGILSYLIIGVPVFI-THLYDDVSPAELN---GIVSRNAFFYL---YLIYSFSTVLKLTGDFGE---LAGVTHRVMELHEELNRLHSDCLETDRPPSTVPSSVVVIASDEDDKSASRHMQEIHGKQMSLERDEQEEEEAQYLLGGKTGQEDDWPDDGVAITVDSATLSPPNDHSHLIVQLLSLQIIQGQTLLITGDSGCGKSSLLRMFAGLWHCSSGKMDCHWRRLTSNLFFLAQKPYFPSGNTTLRQQIVYPVKALQV------DKDVARITQILEWVKMEHLVERCGGLDTPVEWDWMKTLSPGELQRLSLARVFYTKPRIVFLDESTSAIGFELEMAIYRKLQEEKITFVSIGHRYSLKQFHDMELRVKGRSGEWSLHDIDTASIAS 674          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Fly
Match: ABCD (gene:FBgn0039890 transcript:FBtr0089146)

HSP 1 Score: 621.698 bits (1602), Expect = 0.000e+0
Identity = 321/598 (53.68%), Postives = 417/598 (69.73%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT--------NNAIEYQGQSNVAK-----LDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPK----NTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDE 2077
            E+ LL VHTFCL+ RTFLSIYVA L+G +V+ IV++D+ +F + LLK+  IA+PATF+NS IRFLE +LS+ FRT+LV + Y+LYFK+Q YYRV N+D RI+N D  LTEDISVF++S+AHLYS LTKP  DL L+  +L + ++   A+I     ++ GV+  T   LR++SPKFG LV+EEA   GYLR +HSRII N+EEIAFY GH+VE   L +AY  L+ Q   I  QKLW++M+EQF MKYVWS TGM MVS+PILT +             +  VSERTQ  T ARNLL ++A A+ER+++SYKE+  L+GYT RV  ++ VF + +  VY  T        N  IE++    +AK      DD  P    I L  VP+VTPN D+VVP+L+L I  G H+LITGPNGCGKSSLFRI  GLWPIY G+L  P        M++IPQ+PY+ +G+L DQIIYPD    MK K +T+ +L+ IL +V LE I  R+   DV +DW ++ SGGEKQR+ +ARLFYH+P++ALLDECTSAVSIDVES+IYE A  MG+TLLT+THRP+LWK+H  +L+FDG G W    +  DE
Sbjct:  128 ETGLLSVHTFCLISRTFLSIYVAALEGALVKFIVRKDIKQFALVLLKWFGIAIPATFVNSMIRFLESKLSLAFRTRLVRHSYRLYFKNQNYYRVSNLDGRIENADHRLTEDISVFANSVAHLYSSLTKPCFDLMLIGLALMRSSKKMKANIITGPALSIGVIALTAHILRIVSPKFGQLVSEEANRYGYLRHIHSRIITNAEEIAFYGGHKVEMQQLRQAYNRLVNQMTTIFNQKLWFIMLEQFFMKYVWSGTGMIMVSLPILTGSDVGLGTVPNTAISESRVSERTQYLTTARNLLISAADAIERLMSSYKEIVSLAGYTFRVAGMMDVFEETALGVYCKTSVMESNQSNGIIEFRNGKPIAKGRIIYSDD--PKNMSISLRAVPVVTPNCDIVVPKLTLCIEPGVHLLITGPNGCGKSSLFRILSGLWPIYAGELHIPRPVKDVPCMFYIPQRPYMSIGSLCDQIIYPDTREDMKRKHITENELRSILKMVSLEHIAQRD-SFDVVRDWKDILSGGEKQRMAIARLFYHRPRYALLDECTSAVSIDVESSIYEIAKGMGITLLTITHRPTLWKYHTHILEFDGLGNWQFRKMNSDE 722          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Fly
Match: ABCD (gene:FBgn0039890 transcript:FBtr0089150)

HSP 1 Score: 621.698 bits (1602), Expect = 0.000e+0
Identity = 321/598 (53.68%), Postives = 417/598 (69.73%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT--------NNAIEYQGQSNVAK-----LDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPK----NTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDE 2077
            E+ LL VHTFCL+ RTFLSIYVA L+G +V+ IV++D+ +F + LLK+  IA+PATF+NS IRFLE +LS+ FRT+LV + Y+LYFK+Q YYRV N+D RI+N D  LTEDISVF++S+AHLYS LTKP  DL L+  +L + ++   A+I     ++ GV+  T   LR++SPKFG LV+EEA   GYLR +HSRII N+EEIAFY GH+VE   L +AY  L+ Q   I  QKLW++M+EQF MKYVWS TGM MVS+PILT +             +  VSERTQ  T ARNLL ++A A+ER+++SYKE+  L+GYT RV  ++ VF + +  VY  T        N  IE++    +AK      DD  P    I L  VP+VTPN D+VVP+L+L I  G H+LITGPNGCGKSSLFRI  GLWPIY G+L  P        M++IPQ+PY+ +G+L DQIIYPD    MK K +T+ +L+ IL +V LE I  R+   DV +DW ++ SGGEKQR+ +ARLFYH+P++ALLDECTSAVSIDVES+IYE A  MG+TLLT+THRP+LWK+H  +L+FDG G W    +  DE
Sbjct:  128 ETGLLSVHTFCLISRTFLSIYVAALEGALVKFIVRKDIKQFALVLLKWFGIAIPATFVNSMIRFLESKLSLAFRTRLVRHSYRLYFKNQNYYRVSNLDGRIENADHRLTEDISVFANSVAHLYSSLTKPCFDLMLIGLALMRSSKKMKANIITGPALSIGVIALTAHILRIVSPKFGQLVSEEANRYGYLRHIHSRIITNAEEIAFYGGHKVEMQQLRQAYNRLVNQMTTIFNQKLWFIMLEQFFMKYVWSGTGMIMVSLPILTGSDVGLGTVPNTAISESRVSERTQYLTTARNLLISAADAIERLMSSYKEIVSLAGYTFRVAGMMDVFEETALGVYCKTSVMESNQSNGIIEFRNGKPIAKGRIIYSDD--PKNMSISLRAVPVVTPNCDIVVPKLTLCIEPGVHLLITGPNGCGKSSLFRILSGLWPIYAGELHIPRPVKDVPCMFYIPQRPYMSIGSLCDQIIYPDTREDMKRKHITENELRSILKMVSLEHIAQRD-SFDVVRDWKDILSGGEKQRMAIARLFYHRPRYALLDECTSAVSIDVESSIYEIAKGMGITLLTITHRPTLWKYHTHILEFDGLGNWQFRKMNSDE 722          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Fly
Match: ABCD (gene:FBgn0039890 transcript:FBtr0089148)

HSP 1 Score: 621.698 bits (1602), Expect = 0.000e+0
Identity = 321/598 (53.68%), Postives = 417/598 (69.73%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT--------NNAIEYQGQSNVAK-----LDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPK----NTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDE 2077
            E+ LL VHTFCL+ RTFLSIYVA L+G +V+ IV++D+ +F + LLK+  IA+PATF+NS IRFLE +LS+ FRT+LV + Y+LYFK+Q YYRV N+D RI+N D  LTEDISVF++S+AHLYS LTKP  DL L+  +L + ++   A+I     ++ GV+  T   LR++SPKFG LV+EEA   GYLR +HSRII N+EEIAFY GH+VE   L +AY  L+ Q   I  QKLW++M+EQF MKYVWS TGM MVS+PILT +             +  VSERTQ  T ARNLL ++A A+ER+++SYKE+  L+GYT RV  ++ VF + +  VY  T        N  IE++    +AK      DD  P    I L  VP+VTPN D+VVP+L+L I  G H+LITGPNGCGKSSLFRI  GLWPIY G+L  P        M++IPQ+PY+ +G+L DQIIYPD    MK K +T+ +L+ IL +V LE I  R+   DV +DW ++ SGGEKQR+ +ARLFYH+P++ALLDECTSAVSIDVES+IYE A  MG+TLLT+THRP+LWK+H  +L+FDG G W    +  DE
Sbjct:  128 ETGLLSVHTFCLISRTFLSIYVAALEGALVKFIVRKDIKQFALVLLKWFGIAIPATFVNSMIRFLESKLSLAFRTRLVRHSYRLYFKNQNYYRVSNLDGRIENADHRLTEDISVFANSVAHLYSSLTKPCFDLMLIGLALMRSSKKMKANIITGPALSIGVIALTAHILRIVSPKFGQLVSEEANRYGYLRHIHSRIITNAEEIAFYGGHKVEMQQLRQAYNRLVNQMTTIFNQKLWFIMLEQFFMKYVWSGTGMIMVSLPILTGSDVGLGTVPNTAISESRVSERTQYLTTARNLLISAADAIERLMSSYKEIVSLAGYTFRVAGMMDVFEETALGVYCKTSVMESNQSNGIIEFRNGKPIAKGRIIYSDD--PKNMSISLRAVPVVTPNCDIVVPKLTLCIEPGVHLLITGPNGCGKSSLFRILSGLWPIYAGELHIPRPVKDVPCMFYIPQRPYMSIGSLCDQIIYPDTREDMKRKHITENELRSILKMVSLEHIAQRD-SFDVVRDWKDILSGGEKQRMAIARLFYHRPRYALLDECTSAVSIDVESSIYEIAKGMGITLLTITHRPTLWKYHTHILEFDGLGNWQFRKMNSDE 722          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Fly
Match: ABCD (gene:FBgn0039890 transcript:FBtr0089147)

HSP 1 Score: 621.698 bits (1602), Expect = 0.000e+0
Identity = 321/598 (53.68%), Postives = 417/598 (69.73%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT--------NNAIEYQGQSNVAK-----LDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPK----NTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDE 2077
            E+ LL VHTFCL+ RTFLSIYVA L+G +V+ IV++D+ +F + LLK+  IA+PATF+NS IRFLE +LS+ FRT+LV + Y+LYFK+Q YYRV N+D RI+N D  LTEDISVF++S+AHLYS LTKP  DL L+  +L + ++   A+I     ++ GV+  T   LR++SPKFG LV+EEA   GYLR +HSRII N+EEIAFY GH+VE   L +AY  L+ Q   I  QKLW++M+EQF MKYVWS TGM MVS+PILT +             +  VSERTQ  T ARNLL ++A A+ER+++SYKE+  L+GYT RV  ++ VF + +  VY  T        N  IE++    +AK      DD  P    I L  VP+VTPN D+VVP+L+L I  G H+LITGPNGCGKSSLFRI  GLWPIY G+L  P        M++IPQ+PY+ +G+L DQIIYPD    MK K +T+ +L+ IL +V LE I  R+   DV +DW ++ SGGEKQR+ +ARLFYH+P++ALLDECTSAVSIDVES+IYE A  MG+TLLT+THRP+LWK+H  +L+FDG G W    +  DE
Sbjct:  128 ETGLLSVHTFCLISRTFLSIYVAALEGALVKFIVRKDIKQFALVLLKWFGIAIPATFVNSMIRFLESKLSLAFRTRLVRHSYRLYFKNQNYYRVSNLDGRIENADHRLTEDISVFANSVAHLYSSLTKPCFDLMLIGLALMRSSKKMKANIITGPALSIGVIALTAHILRIVSPKFGQLVSEEANRYGYLRHIHSRIITNAEEIAFYGGHKVEMQQLRQAYNRLVNQMTTIFNQKLWFIMLEQFFMKYVWSGTGMIMVSLPILTGSDVGLGTVPNTAISESRVSERTQYLTTARNLLISAADAIERLMSSYKEIVSLAGYTFRVAGMMDVFEETALGVYCKTSVMESNQSNGIIEFRNGKPIAKGRIIYSDD--PKNMSISLRAVPVVTPNCDIVVPKLTLCIEPGVHLLITGPNGCGKSSLFRILSGLWPIYAGELHIPRPVKDVPCMFYIPQRPYMSIGSLCDQIIYPDTREDMKRKHITENELRSILKMVSLEHIAQRD-SFDVVRDWKDILSGGEKQRMAIARLFYHRPRYALLDECTSAVSIDVESSIYEIAKGMGITLLTITHRPTLWKYHTHILEFDGLGNWQFRKMNSDE 722          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Fly
Match: ABCD (gene:FBgn0039890 transcript:FBtr0308247)

HSP 1 Score: 621.698 bits (1602), Expect = 0.000e+0
Identity = 321/598 (53.68%), Postives = 417/598 (69.73%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT--------NNAIEYQGQSNVAK-----LDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPK----NTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDE 2077
            E+ LL VHTFCL+ RTFLSIYVA L+G +V+ IV++D+ +F + LLK+  IA+PATF+NS IRFLE +LS+ FRT+LV + Y+LYFK+Q YYRV N+D RI+N D  LTEDISVF++S+AHLYS LTKP  DL L+  +L + ++   A+I     ++ GV+  T   LR++SPKFG LV+EEA   GYLR +HSRII N+EEIAFY GH+VE   L +AY  L+ Q   I  QKLW++M+EQF MKYVWS TGM MVS+PILT +             +  VSERTQ  T ARNLL ++A A+ER+++SYKE+  L+GYT RV  ++ VF + +  VY  T        N  IE++    +AK      DD  P    I L  VP+VTPN D+VVP+L+L I  G H+LITGPNGCGKSSLFRI  GLWPIY G+L  P        M++IPQ+PY+ +G+L DQIIYPD    MK K +T+ +L+ IL +V LE I  R+   DV +DW ++ SGGEKQR+ +ARLFYH+P++ALLDECTSAVSIDVES+IYE A  MG+TLLT+THRP+LWK+H  +L+FDG G W    +  DE
Sbjct:  128 ETGLLSVHTFCLISRTFLSIYVAALEGALVKFIVRKDIKQFALVLLKWFGIAIPATFVNSMIRFLESKLSLAFRTRLVRHSYRLYFKNQNYYRVSNLDGRIENADHRLTEDISVFANSVAHLYSSLTKPCFDLMLIGLALMRSSKKMKANIITGPALSIGVIALTAHILRIVSPKFGQLVSEEANRYGYLRHIHSRIITNAEEIAFYGGHKVEMQQLRQAYNRLVNQMTTIFNQKLWFIMLEQFFMKYVWSGTGMIMVSLPILTGSDVGLGTVPNTAISESRVSERTQYLTTARNLLISAADAIERLMSSYKEIVSLAGYTFRVAGMMDVFEETALGVYCKTSVMESNQSNGIIEFRNGKPIAKGRIIYSDD--PKNMSISLRAVPVVTPNCDIVVPKLTLCIEPGVHLLITGPNGCGKSSLFRILSGLWPIYAGELHIPRPVKDVPCMFYIPQRPYMSIGSLCDQIIYPDTREDMKRKHITENELRSILKMVSLEHIAQRD-SFDVVRDWKDILSGGEKQRMAIARLFYHRPRYALLDECTSAVSIDVESSIYEIAKGMGITLLTITHRPTLWKYHTHILEFDGLGNWQFRKMNSDE 722          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Zebrafish
Match: abcd1 (ATP-binding cassette, sub-family D (ALD), member 1 [Source:NCBI gene;Acc:566367])

HSP 1 Score: 649.432 bits (1674), Expect = 0.000e+0
Identity = 335/620 (54.03%), Postives = 444/620 (71.61%), Query Frame = 2
Query:  266 VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGS------FVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAI---EYQGQSNVAK----------LDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            VN  FF RL  LLKI+FP+   KE  LL  H+  L+ RTFLSIYVA LDG+IV++IV++D   F+++L K+LLIA+PATF+NS IR+LE +L++ FRT+LV + Y LYF  QTYYRV N+D R+ N DQSLTED+ +F++S+AHLYS LTKP LD+ +  ++L K A ++GA+   P +IA  VV  T + LR  SP+FG LVAEEA+ KG LR++HSRII NSEEIAFY GH++E   L ++Y  L +Q N I  ++LWYVM+EQFLMKY+WS++G+ MV++PI+TATG     S       +D   +  VSERTQ FT AR+LL  +A AVER++ SYKEVTEL+GYT+RV+E+  VF D+   VYR +   +   E     NV                +     I+   +PI+TP GDVVV  L++++++G H+LITGPNGCGKSSLFRI  GLWP+Y G L  P  + M++IPQ+PY+ +GTLRDQ+IYP ++ +M+ KG+TD+ L+EIL  V L  I+ REGG D   DW +V SGGEKQR+GMAR+FYHKPQ+ALLDECTSAVSIDVE  I+E A   G++LL++THRPSLWK+H+ LL+FDGEGGW    L+
Sbjct:   74 VNREFFDRLIRLLKILFPRLFCKELGLLGFHSLALISRTFLSIYVANLDGQIVKTIVKKDPRAFVVELTKWLLIAIPATFVNSAIRYLEGQLTLAFRTRLVTHAYMLYFSDQTYYRVSNMDGRLANPDQSLTEDVVMFAASVAHLYSNLTKPILDVVVTCYTLIKTAESKGANTTWPSVIAGIVVALTAKVLRAFSPRFGKLVAEEARRKGDLRYMHSRIIANSEEIAFYGGHKIEMLQLQRSYNSLSRQINLILFKRLWYVMLEQFLMKYLWSASGLVMVAVPIITATGYSKYDSEDVKQAALDMKEEDLVSERTQAFTTARSLLNAAADAVERIMVSYKEVTELAGYTARVYEMFEVFEDVRDGVYRRSATEVKPEETGAPQNVTHGMRVEGPLQIRGQVIDVEQGIKCENLPIITPTGDVVVSSLNMQVDEGMHLLITGPNGCGKSSLFRILSGLWPVYSGVLYKPSPDHMFYIPQRPYMSVGTLRDQVIYPHSVQEMQEKGITDRQLEEILQTVSLRYILEREGGWDAVSDWKDVLSGGEKQRMGMARMFYHKPQYALLDECTSAVSIDVEGKIFEAAKDAGISLLSITHRPSLWKYHSHLLQFDGEGGWRFEKLD 693          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Zebrafish
Match: abcd1 (ATP-binding cassette, sub-family D (ALD), member 1 [Source:NCBI gene;Acc:566367])

HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0
Identity = 293/557 (52.60%), Postives = 392/557 (70.38%), Query Frame = 2
Query:  266 VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGS------FVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAI---EYQGQSNVAK----------LDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHK 1879
            VN  FF RL  LLKI+FP+   KE  LL  H+  L+ RTFLSIYVA LDG+IV++IV++D   F+++L K+LLIA+PATF+NS IR+LE +L++ FRT+LV + Y LYF  QTYYRV N+D R+ N DQSLTED+ +F++S+AHLYS LTKP LD+ +  ++L K A ++GA+   P +IA  VV  T + LR  SP+FG LVAEEA+ KG LR++HSRII NSEEIAFY GH++E   L ++Y  L +Q N I  ++LWYVM+EQFLMKY+WS++G+ MV++PI+TATG     S       +D   +  VSERTQ FT AR+LL  +A AVER++ SYKEVTEL+GYT+RV+E+  VF D+   VYR +   +   E     NV                +     I+   +PI+TP GDVVV  L++++++G H+LITGPNGCGKSSLFRI  GLWP+Y G L  P  + M++IPQ+PY+ +GTLRDQ+IYP ++ +M+ KG+TD+ L+EIL  V L  I+ REGG D   DW +V SGGEKQR+GMAR+FYHK
Sbjct:   74 VNREFFDRLIRLLKILFPRLFCKELGLLGFHSLALISRTFLSIYVANLDGQIVKTIVKKDPRAFVVELTKWLLIAIPATFVNSAIRYLEGQLTLAFRTRLVTHAYMLYFSDQTYYRVSNMDGRLANPDQSLTEDVVMFAASVAHLYSNLTKPILDVVVTCYTLIKTAESKGANTTWPSVIAGIVVALTAKVLRAFSPRFGKLVAEEARRKGDLRYMHSRIIANSEEIAFYGGHKIEMLQLQRSYNSLSRQINLILFKRLWYVMLEQFLMKYLWSASGLVMVAVPIITATGYSKYDSEDVKQAALDMKEEDLVSERTQAFTTARSLLNAAADAVERIMVSYKEVTELAGYTARVYEMFEVFEDVRDGVYRRSATEVKPEETGAPQNVTHGMRVEGPLQIRGQVIDVEQGIKCENLPIITPTGDVVVSSLNMQVDEGMHLLITGPNGCGKSSLFRILSGLWPVYSGVLYKPSPDHMFYIPQRPYMSVGTLRDQVIYPHSVQEMQEKGITDRQLEEILQTVSLRYILEREGGWDAVSDWKDVLSGGEKQRMGMARMFYHK 630          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Zebrafish
Match: abcd3a (ATP-binding cassette, sub-family D (ALD), member 3a [Source:ZFIN;Acc:ZDB-GENE-040426-2868])

HSP 1 Score: 414.461 bits (1064), Expect = 8.865e-135
Identity = 236/628 (37.58%), Postives = 362/628 (57.64%), Query Frame = 2
Query:  221 SNVNEMKTLENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPAT-------NYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDEIK 2083
            + +N  K  + E + V+ LFF R+  +LKI+ PKF SKE++ L +    L+ RT+  +++      I  +I+ R    F   L  F+        +N+F++     L +CFR +L ++ Y  Y K  TYY++ N+D RI N DQ LT+D+  F +S+  LYS L+KP LD+ L  F L      +G     P  + A ++IS G FL  +    G +   E K++G  R+V+SR+I NSEEIAFY+G+  E   +   +++L+   +     +    M++  + KY  +  G  +VS P L  +  R+  S          +E  + +  +  +L   + A+ R++ + +E+T LSG+T+R+ EL+ V  +L+   Y  T   +  Q + + ++    VP +       N I+    P+ TPNGDV++ +L   +  G ++L+ GPNGCGKSSLFR+   LWP++GG LT P +  ++++PQ+PY+ LG+LRDQ+IYPD     K KG++D  L+E LD VQL  I+ REG  D  +DW++V SGGEKQR+ MARLFYHKPQFA+LDECTSAVS+DVE  IY    K+G+TL TV+HR SLWK H   L  DG G +    +  + ++
Sbjct:   43 NELNSEKDGKKERAAVDKLFFIRISRILKIMVPKFFSKETWYLLLIAVMLVTRTYCDVWMIQNGTMIESAIIGRSTKGFKKYLFNFMTAMPIIALVNNFLKLGLNELKLCFRVRLTKHLYDEYLKGYTYYKMGNLDNRIANADQLLTQDVERFCNSVVDLYSNLSKPLLDIGLYIFKLTTAIGAQG-----PATMMAYLLIS-GLFLTRLRRPIGKMTVTEQKYEGEYRYVNSRLITNSEEIAFYNGNTREKQTIHSTFKKLVDHLHNFIFFRFSMGMVDSIIAKYFATVVGYLVVSRPFLNLSHSRHLNS--------SHAELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLSGFTARITELMRVLKELNSGKYERT---MVSQSEKDASEKLTLVPGSGRIINIDNIIKFDHTPLATPNGDVLIRDLCFEVKSGTNVLVCGPNGCGKSSLFRVLGELWPLFGGNLTKPERGKLFYVPQRPYMTLGSLRDQVIYPDTHESQKKKGISDLVLKEYLDNVQLGHILDREGSWDTVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKPITPETVE 653          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Zebrafish
Match: abcd3a (ATP-binding cassette, sub-family D (ALD), member 3a [Source:ZFIN;Acc:ZDB-GENE-040426-2868])

HSP 1 Score: 413.69 bits (1062), Expect = 1.977e-134
Identity = 236/628 (37.58%), Postives = 362/628 (57.64%), Query Frame = 2
Query:  221 SNVNEMKTLENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPAT-------NYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDEIK 2083
            + +N  K  + E + V+ LFF R+  +LKI+ PKF SKE++ L +    L+ RT+  +++      I  +I+ R    F   L  F+        +N+F++     L +CFR +L ++ Y  Y K  TYY++ N+D RI N DQ LT+D+  F +S+  LYS L+KP LD+ L  F L      +G     P  + A ++IS G FL  +    G +   E K++G  R+V+SR+I NSEEIAFY+G+  E   +   +++L+   +     +    M++  + KY  +  G  +VS P L  +  R+  S          +E  + +  +  +L   + A+ R++ + +E+T LSG+T+R+ EL+ V  +L+   Y  T   +  Q + + ++    VP +       N I+    P+ TPNGDV++ +L   +  G ++L+ GPNGCGKSSLFR+   LWP++GG LT P +  ++++PQ+PY+ LG+LRDQ+IYPD     K KG++D  L+E LD VQL  I+ REG  D  +DW++V SGGEKQR+ MARLFYHKPQFA+LDECTSAVS+DVE  IY    K+G+TL TV+HR SLWK H   L  DG G +    +  + ++
Sbjct:   43 NELNSEKDGKKERAAVDKLFFIRISRILKIMVPKFFSKETWYLLLIAVMLVTRTYCDVWMIQNGTMIESAIIGRSTKGFKKYLFNFMTAMPIIALVNNFLKLGLNELKLCFRVRLTKHLYDEYLKGYTYYKMGNLDNRIANADQLLTQDVERFCNSVVDLYSNLSKPLLDIGLYIFKLTTAIGAQG-----PATMMAYLLIS-GLFLTRLRRPIGKMTVTEQKYEGEYRYVNSRLITNSEEIAFYNGNTREKQTIHSTFKKLVDHLHNFIFFRFSMGMVDSIIAKYFATVVGYLVVSRPFLNLSHPRHLNS--------SHAELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLSGFTARITELMRVLKELNSGKYERT---MVSQSEKDASEKLTLVPGSGRIINIDNIIKFDHTPLATPNGDVLIRDLCFEVKSGTNVLVCGPNGCGKSSLFRVLGELWPLFGGNLTKPERGKLFYVPQRPYMTLGSLRDQVIYPDTHESQKKKGISDLVLKEYLDNVQLGHILDREGSWDTVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKPITPETVE 653          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Zebrafish
Match: abcd3a (ATP-binding cassette, sub-family D (ALD), member 3a [Source:ZFIN;Acc:ZDB-GENE-040426-2868])

HSP 1 Score: 413.69 bits (1062), Expect = 1.977e-134
Identity = 236/628 (37.58%), Postives = 362/628 (57.64%), Query Frame = 2
Query:  221 SNVNEMKTLENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPAT-------NYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDEIK 2083
            + +N  K  + E + V+ LFF R+  +LKI+ PKF SKE++ L +    L+ RT+  +++      I  +I+ R    F   L  F+        +N+F++     L +CFR +L ++ Y  Y K  TYY++ N+D RI N DQ LT+D+  F +S+  LYS L+KP LD+ L  F L      +G     P  + A ++IS G FL  +    G +   E K++G  R+V+SR+I NSEEIAFY+G+  E   +   +++L+   +     +    M++  + KY  +  G  +VS P L  +  R+  S          +E  + +  +  +L   + A+ R++ + +E+T LSG+T+R+ EL+ V  +L+   Y  T   +  Q + + ++    VP +       N I+    P+ TPNGDV++ +L   +  G ++L+ GPNGCGKSSLFR+   LWP++GG LT P +  ++++PQ+PY+ LG+LRDQ+IYPD     K KG++D  L+E LD VQL  I+ REG  D  +DW++V SGGEKQR+ MARLFYHKPQFA+LDECTSAVS+DVE  IY    K+G+TL TV+HR SLWK H   L  DG G +    +  + ++
Sbjct:   43 NELNSEKDGKKERAAVDKLFFIRISRILKIMVPKFFSKETWYLLLIAVMLVTRTYCDVWMIQNGTMIESAIIGRSTKGFKKYLFNFMTAMPIIALVNNFLKLGLNELKLCFRVRLTKHLYDEYLKGYTYYKMGNLDNRIANADQLLTQDVERFCNSVVDLYSNLSKPLLDIGLYIFKLTTAIGAQG-----PATMMAYLLIS-GLFLTRLRRPIGKMTVTEQKYEGEYRYVNSRLITNSEEIAFYNGNTREKQTIHSTFKKLVDHLHNFIFFRFSMGMVDSIIAKYFATVVGYLVVSRPFLNLSHPRHLNS--------SHAELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLSGFTARITELMRVLKELNSGKYERT---MVSQSEKDASEKLTLVPGSGRIINIDNIIKFDHTPLATPNGDVLIRDLCFEVKSGTNVLVCGPNGCGKSSLFRVLGELWPLFGGNLTKPERGKLFYVPQRPYMTLGSLRDQVIYPDTHESQKKKGISDLVLKEYLDNVQLGHILDREGSWDTVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKPITPETVE 653          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Xenopus
Match: scrib (scribbled planar cell polarity protein [Source:Xenbase;Acc:XB-GENE-1018501])

HSP 1 Score: 663.685 bits (1711), Expect = 0.000e+0
Identity = 344/617 (55.75%), Postives = 454/617 (73.58%), Query Frame = 2
Query:  266 VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGG-----VSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRV-----TNNAIEYQGQSNV---AKLD---DAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            VN+ F+++L  L +I+FPK +SKE  LL VH+  L+ RTFLS+YVAGLDGKIV+SIV++    FL+QL+K+LLIA+PATF+NS IR+LE +L++  RT+LV++ Y+ YF  QTYY++ N+D R+ N DQSLTEDI +FS S+AHLYS LTKP LD+ L S++L + AR+RGA+   P ++A  VV +T + L+  SPKFG LVAEEA  KGYLR+VHSRII N EEIAFY GH+VE   L K+Y  L  Q N I  ++LWYVMIEQFLMKYVWS +G+ MV++PI+TATG      F D D + G     VSERT+ FT ARNLL + A A+ER+++SYKEVTEL+GYT+RV+ + +VF ++ + +Y+      T N  +++ ++ +     L+     V   + I    VPI+TPNGDVVV +L++++ +G H+LITGPNGCGKSSLFRI  GLWP+Y G L  PP   M++IPQ+PY+ +GTLRDQ+IYPD L  M  KG  D+DL+ ILDIV L  I+ REGG D   DW +V SGGEKQR+GMAR+FYH+PQ+ALLDECTSAVSIDVE  I++ A   G++LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   72 VNAEFYRQLLELRRILFPKLLSKELGLLSVHSLALISRTFLSVYVAGLDGKIVKSIVEKKPRNFLMQLMKWLLIAIPATFVNSAIRYLEGKLALALRTRLVDHAYRTYFADQTYYKIINMDSRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVVLTSYTLIQTARSRGANPLGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMTKLQKSYMALADQINLILSKRLWYVMIEQFLMKYVWSGSGLVMVAVPIITATG------FADSDLEDGQKQAMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTARVYNMFSVFNEVKKGIYKRSLIQETKNNKKHKEKTELHIDGPLEIKGKVVDVDHGIICEDVPIITPNGDVVVSKLNIKVEEGMHLLITGPNGCGKSSLFRILGGLWPVYEGVLYKPPPQKMFYIPQRPYMSIGTLRDQVIYPDLLEDMHEKGYQDQDLEHILDIVHLNHIVQREGGWDAFTDWKDVLSGGEKQRMGMARMFYHRPQYALLDECTSAVSIDVEGKIFQAAKDAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLD 682          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Xenopus
Match: scrib (scribbled planar cell polarity protein [Source:Xenbase;Acc:XB-GENE-1018501])

HSP 1 Score: 663.3 bits (1710), Expect = 0.000e+0
Identity = 344/617 (55.75%), Postives = 454/617 (73.58%), Query Frame = 2
Query:  266 VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGG-----VSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRV-----TNNAIEYQGQSNV---AKLD---DAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            VN+ F+++L  L +I+FPK +SKE  LL VH+  L+ RTFLS+YVAGLDGKIV+SIV++    FL+QL+K+LLIA+PATF+NS IR+LE +L++  RT+LV++ Y+ YF  QTYY++ N+D R+ N DQSLTEDI +FS S+AHLYS LTKP LD+ L S++L + AR+RGA+   P ++A  VV +T + L+  SPKFG LVAEEA  KGYLR+VHSRII N EEIAFY GH+VE   L K+Y  L  Q N I  ++LWYVMIEQFLMKYVWS +G+ MV++PI+TATG      F D D + G     VSERT+ FT ARNLL + A A+ER+++SYKEVTEL+GYT+RV+ + +VF ++ + +Y+      T N  +++ ++ +     L+     V   + I    VPI+TPNGDVVV +L++++ +G H+LITGPNGCGKSSLFRI  GLWP+Y G L  PP   M++IPQ+PY+ +GTLRDQ+IYPD L  M  KG  D+DL+ ILDIV L  I+ REGG D   DW +V SGGEKQR+GMAR+FYH+PQ+ALLDECTSAVSIDVE  I++ A   G++LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   72 VNAEFYRQLLELRRILFPKLLSKELGLLSVHSLALISRTFLSVYVAGLDGKIVKSIVEKKPRNFLMQLMKWLLIAIPATFVNSAIRYLEGKLALALRTRLVDHAYRTYFADQTYYKIINMDSRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVVLTSYTLIQTARSRGANPLGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMTKLQKSYMALADQINLILSKRLWYVMIEQFLMKYVWSGSGLVMVAVPIITATG------FADSDLEDGQKQAMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTARVYNMFSVFNEVKKGIYKRSLIQETKNNKKHKEKTELHIDGPLEIKGKVVDVDHGIICEDVPIITPNGDVVVSKLNIKVEEGMHLLITGPNGCGKSSLFRILGGLWPVYEGVLYKPPPQKMFYIPQRPYMSIGTLRDQVIYPDLLEDMHEKGYQDQDLEHILDIVHLNHIVQREGGWDAFTDWKDVLSGGEKQRMGMARMFYHRPQYALLDECTSAVSIDVEGKIFQAAKDAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLD 682          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Xenopus
Match: scrib (scribbled planar cell polarity protein [Source:Xenbase;Acc:XB-GENE-1018501])

HSP 1 Score: 662.914 bits (1709), Expect = 0.000e+0
Identity = 344/617 (55.75%), Postives = 454/617 (73.58%), Query Frame = 2
Query:  266 VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGG-----VSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRV-----TNNAIEYQGQSNV---AKLD---DAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            VN+ F+++L  L +I+FPK +SKE  LL VH+  L+ RTFLS+YVAGLDGKIV+SIV++    FL+QL+K+LLIA+PATF+NS IR+LE +L++  RT+LV++ Y+ YF  QTYY++ N+D R+ N DQSLTEDI +FS S+AHLYS LTKP LD+ L S++L + AR+RGA+   P ++A  VV +T + L+  SPKFG LVAEEA  KGYLR+VHSRII N EEIAFY GH+VE   L K+Y  L  Q N I  ++LWYVMIEQFLMKYVWS +G+ MV++PI+TATG      F D D + G     VSERT+ FT ARNLL + A A+ER+++SYKEVTEL+GYT+RV+ + +VF ++ + +Y+      T N  +++ ++ +     L+     V   + I    VPI+TPNGDVVV +L++++ +G H+LITGPNGCGKSSLFRI  GLWP+Y G L  PP   M++IPQ+PY+ +GTLRDQ+IYPD L  M  KG  D+DL+ ILDIV L  I+ REGG D   DW +V SGGEKQR+GMAR+FYH+PQ+ALLDECTSAVSIDVE  I++ A   G++LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   72 VNAEFYRQLLELRRILFPKLLSKELGLLSVHSLALISRTFLSVYVAGLDGKIVKSIVEKKPRNFLMQLMKWLLIAIPATFVNSAIRYLEGKLALALRTRLVDHAYRTYFADQTYYKIINMDSRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVVLTSYTLIQTARSRGANPLGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMTKLQKSYMALADQINLILSKRLWYVMIEQFLMKYVWSGSGLVMVAVPIITATG------FADSDLEDGQKQAMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTARVYNMFSVFNEVKKGIYKRSLIQETKNNKKHKEKTELHIDGPLEIKGKVVDVDHGIICEDVPIITPNGDVVVSKLNIKVEEGMHLLITGPNGCGKSSLFRILGGLWPVYEGVLYKPPPQKMFYIPQRPYMSIGTLRDQVIYPDLLEDMHEKGYQDQDLEHILDIVHLNHIVQREGGWDAFTDWKDVLSGGEKQRMGMARMFYHRPQYALLDECTSAVSIDVEGKIFQAAKDAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLD 682          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Xenopus
Match: scrib (scribbled planar cell polarity protein [Source:Xenbase;Acc:XB-GENE-1018501])

HSP 1 Score: 658.292 bits (1697), Expect = 0.000e+0
Identity = 340/620 (54.84%), Postives = 450/620 (72.58%), Query Frame = 2
Query:  266 VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT-------------------NNAIEYQGQSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            VN+ F+++L  L +I+FPK +SKE  LL VH+  L+ RTFLS+YVAGLDGKIV+SIV++    FL+QL+K+LLIA+PATF+NS IR+LE +L++  RT+LV++ Y+ YF  QTYY++ N+D R+ N DQSLTEDI +FS S+AHLYS LTKP LD+ L S++L + AR+RGA+   P ++A  VV +T + L+  SPKFG LVAEEA  KGYLR+VHSRII N EEIAFY GH+VE   L K+Y  L  Q N I  ++LWYVMIEQFLMKYVWS +G+ MV++PI+TATG  +     D      VSERT+ FT ARNLL + A A+ER+++SYKEVTEL+GYT+RV+ + +VF ++ + +Y+ +                   +  +E +G+  V  +D  +   +      VPI+TPNGDVVV +L++++ +G H+LITGPNGCGKSSLFRI  GLWP+Y G L  PP   M++IPQ+PY+ +GTLRDQ+IYPD L  M  KG  D+DL+ ILDIV L  I+ REGG D   DW +V SGGEKQR+GMAR+FYH+PQ+ALLDECTSAVSIDVE  I++ A   G++LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   71 VNAEFYRQLLELRRILFPKLLSKELGLLSVHSLALISRTFLSVYVAGLDGKIVKSIVEKKPRNFLMQLMKWLLIAIPATFVNSAIRYLEGKLALALRTRLVDHAYRTYFADQTYYKIINMDSRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVVLTSYTLIQTARSRGANPLGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMTKLQKSYMALADQINLILSKRLWYVMIEQFLMKYVWSGSGLVMVAVPIITATGF-SLLDLEDGQKQAMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTARVYNMFSVFNEVKKGIYKRSLIQETKNNKKHKEKTELHIDGPLEIKGK--VVDVDHGIICED------VPIITPNGDVVVSKLNIKVEEGMHLLITGPNGCGKSSLFRILGGLWPVYEGVLYKPPPQKMFYIPQRPYMSIGTLRDQVIYPDLLEDMHEKGYQDQDLEHILDIVHLNHIVQREGGWDAFTDWKDVLSGGEKQRMGMARMFYHRPQYALLDECTSAVSIDVEGKIFQAAKDAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLD 681          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Xenopus
Match: scrib (scribbled planar cell polarity protein [Source:Xenbase;Acc:XB-GENE-1018501])

HSP 1 Score: 657.522 bits (1695), Expect = 0.000e+0
Identity = 341/612 (55.72%), Postives = 451/612 (73.69%), Query Frame = 2
Query:  266 VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRV-----TNNAIEYQGQSNV---AKLD---DAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            VN+ F+++L  L +I+FPK +SKE  LL VH+  L+ RTFLS+YVAGLDGKIV+SIV++    FL+QL+K+LLIA+PATF+NS IR+LE +L++  RT+LV++ Y+ YF  QTYY++ N+D R+ N DQSLTEDI +FS S+AHLYS LTKP LD+ L S++L + AR+RGA+   P ++A  VV +T + L+  SPKFG LVAEEA  KGYLR+VHSRII N EEIAFY GH+VE   L K+Y  L  Q N I  ++LWYVMIEQFLMKYVWS +G+ MV++PI+TATG  +     D      VSERT+ FT ARNLL + A A+ER+++SYKEVTEL+GYT+RV+ + +VF ++ + +Y+      T N  +++ ++ +     L+     V   + I    VPI+TPNGDVVV +L++++ +G H+LITGPNGCGKSSLFRI  GLWP+Y G L  PP   M++IPQ+PY+ +GTLRDQ+IYPD L  M  KG  D+DL+ ILDIV L  I+ REGG D   DW +V SGGEKQR+GMAR+FYH+PQ+ALLDECTSAVSIDVE  I++ A   G++LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   72 VNAEFYRQLLELRRILFPKLLSKELGLLSVHSLALISRTFLSVYVAGLDGKIVKSIVEKKPRNFLMQLMKWLLIAIPATFVNSAIRYLEGKLALALRTRLVDHAYRTYFADQTYYKIINMDSRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVVLTSYTLIQTARSRGANPLGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMTKLQKSYMALADQINLILSKRLWYVMIEQFLMKYVWSGSGLVMVAVPIITATGF-SLLDLEDGQKQAMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTARVYNMFSVFNEVKKGIYKRSLIQETKNNKKHKEKTELHIDGPLEIKGKVVDVDHGIICEDVPIITPNGDVVVSKLNIKVEEGMHLLITGPNGCGKSSLFRILGGLWPVYEGVLYKPPPQKMFYIPQRPYMSIGTLRDQVIYPDLLEDMHEKGYQDQDLEHILDIVHLNHIVQREGGWDAFTDWKDVLSGGEKQRMGMARMFYHRPQYALLDECTSAVSIDVEGKIFQAAKDAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLD 682          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Mouse
Match: Abcd2 (ATP-binding cassette, sub-family D (ALD), member 2 [Source:MGI Symbol;Acc:MGI:1349467])

HSP 1 Score: 659.062 bits (1699), Expect = 0.000e+0
Identity = 336/612 (54.90%), Postives = 444/612 (72.55%), Query Frame = 2
Query:  266 VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT-----------NNAIEYQGQSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            +N+ FF++L  L KI+FPK ++ E+  LC+H+  L+ RTFLSIYVAGLDGKIV+SIV++    F+I+L+K+L+IA+PATF+NS IR+LE +L++ FRT+LV++ Y+ YF +QTYY+V N+D R+ N DQSLTEDI +FS S+AHLYS LTKP LD+ L S++L + A +RGAS   P ++A  VV +T + L+  SPKFG LVAEEA  KGYLR+VHSRII N EEIAFY GH+VE   L K Y+ L  Q N I  ++LWY+MIEQFLMKYVWSS G+ MV+IPI+TATG   DG   D      VS+RT+ FT ARNLL + A A+ER+++SYKE+TEL+GYT+RV+ +  VF ++ + +Y+ T              +E      +A     +   + I    VPI+TP G+VV   L+ ++ +G H+LITGPNGCGKSSLFRI  GLWP+Y G L  PP   M++IPQ+PY+ LG+LRDQ+IYPD+   M+ KG TD+DL+ IL  V L  I+ REGG D   DW +V SGGEKQR+GMAR+FYHKP++ALLDECTSAVSIDVE  I++ AI  G++LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   80 LNAAFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFANQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVILTSYTLIRTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGSLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKCYKALAYQMNLILSKRLWYIMIEQFLMKYVWSSCGLIMVAIPIITATGF-ADGDLEDGPKQAMVSDRTEAFTTARNLLASGADAIERIMSSYKEITELAGYTARVYNMFWVFDEVKRGIYKRTVTQEPENHSKRGGNLELPLSDTLAIKGTVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQHMFYIPQRPYMSLGSLRDQVIYPDSADDMREKGYTDQDLERILHSVHLYHIVQREGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLD 690          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Mouse
Match: Abcd1 (ATP-binding cassette, sub-family D (ALD), member 1 [Source:MGI Symbol;Acc:MGI:1349215])

HSP 1 Score: 649.047 bits (1673), Expect = 0.000e+0
Identity = 321/602 (53.32%), Postives = 425/602 (70.60%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGS------FVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQG------------------QSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            E+ LL +H+  L+ RTFLS+YVA LDG++ R IV++D   F  QLL++LLIALPATFINS IR+LE +L++ FR++LV + Y LYF  QTYYRV N+D R++N DQSLTED+  F++S+AHLYS LTKP LD+ + S++L + AR+RGA    P  IA  VV  T   LR  SPKFG LVAEEA+ KG LR++HSR++ NSEEIAFY GHEVE  +L  +YQ+L  Q N I L++LWYVM+EQFLMKYVWS++G+ MV++PI+TATG     S       ++   +  VSERT+ FT+ARNLL  +A A ER+++SYKEVTEL+GYT+RV+E+  VF D+    ++ T +  E Q                   Q  V  ++  +   N      +PI+TP G+VVV  L++R+ +G H+LITGPNGCGKSSLFRI  GLWP Y G L  PP   M++IPQ+PY+ +G+LRDQ+IYPD+   M+ KG +++ L+ IL IV L  I+ REGG +   DW +V SGGEKQRIGMAR+FYH+P++ALLDECTSAVSIDVE  I++ A   G+ LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   90 ETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFSWQLLQWLLIALPATFINSAIRYLEGQLALSFRSRLVAHAYGLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYAESDSEAMKKAALEMKEEELVSERTEAFTIARNLLTAAADATERIMSSYKEVTELAGYTARVYEMFQVFEDVKHCRFKRTGDLEEAQAGPGVMVQSGVHVEGPLKIQGQVVDVEQGIICEN------IPIITPTGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYSGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSAEDMRRKGCSEQQLEAILGIVHLRHILQREGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLD 685          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Mouse
Match: Abcd3 (ATP-binding cassette, sub-family D (ALD), member 3 [Source:MGI Symbol;Acc:MGI:1349216])

HSP 1 Score: 421.394 bits (1082), Expect = 2.180e-137
Identity = 240/623 (38.52%), Postives = 363/623 (58.27%), Query Frame = 2
Query:  248 ENEGSK----VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPAT-------NYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDEIK 2083
            E EG K    V+ +F  RL  +LKI+ P+   KE+  L +    L+ RT+  +++      I   I+ R    F   L  F+      + +N+F+++    L +CFR +L  Y Y+ Y +  TYY++ N+D RI N DQ LT+D+  F +S+  LYS L+KPFLD+ L  F L      +G     P  + A +++S G FL  +    G +   E K++G  R+V+SR+I NSEEIAFY+G++ E   +   +++L++  +     +     I+  + KYV +  G  +VS P L     R+  S          SE  + +  +  +L   + A+ R++ + +E+T L+G+T+R+ EL+ V  DL+   Y  T  + + +G    A+    VP         N I+   VP+ TPNGD+++ +LS  +  G ++LI GPNGCGKSSLFR+   LWP++GG+LT P +  ++++PQ+PY+ LGTLRDQ+IYPD     K +G++D+ L+E LD VQL  I+ REGG D  +DW++V SGGEKQR+ MARLFYHKPQFA+LDECTSAVS+DVE  IY    K+G+TL TV+HR SLWK H   L  DG G +    + +D ++
Sbjct:   49 EKEGKKERAVVDKVFLSRLSQILKIMVPRTFCKETGYLLLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSSKDFKRYLFNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTRYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQG-----PASMMAYLLVS-GLFLTRLRRPIGKMTIMEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTIHSVFRKLVEHLHNFIFFRFSMGFIDSIIAKYVATVVGYLVVSRPFLDLAHPRHLHS--------THSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGRYERTMVSQQEKGIEG-AQASPLVPGAGEIINTDNIIKFDHVPLATPNGDILIQDLSFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGKEDQKKRGISDQVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKKITEDTVE 656          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Mouse
Match: Abcd1 (ATP-binding cassette, sub-family D (ALD), member 1 [Source:MGI Symbol;Acc:MGI:1349215])

HSP 1 Score: 389.037 bits (998), Expect = 6.638e-127
Identity = 207/416 (49.76%), Postives = 282/416 (67.79%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGS------FVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQG------------------QSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINK 1510
            E+ LL +H+  L+ RTFLS+YVA LDG++ R IV++D   F  QLL++LLIALPATFINS IR+LE +L++ FR++LV + Y LYF  QTYYRV N+D R++N DQSLTED+  F++S+AHLYS LTKP LD+ + S++L + AR+RGA    P  IA  VV  T   LR  SPKFG LVAEEA+ KG LR++HSR++ NSEEIAFY GHEVE  +L  +YQ+L  Q N I L++LWYVM+EQFLMKYVWS++G+ MV++PI+TATG     S       ++   +  VSERT+ FT+ARNLL  +A A ER+++SYKEVTEL+GYT+RV+E+  VF D+    ++ T +  E Q                   Q  V  ++  +   N      +PI+TP G+VVV  L++R+ +
Sbjct:   90 ETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFSWQLLQWLLIALPATFINSAIRYLEGQLALSFRSRLVAHAYGLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYAESDSEAMKKAALEMKEEELVSERTEAFTIARNLLTAAADATERIMSSYKEVTELAGYTARVYEMFQVFEDVKHCRFKRTGDLEEAQAGPGVMVQSGVHVEGPLKIQGQVVDVEQGIICEN------IPIITPTGEVVVASLNIRVGQ 499          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Mouse
Match: Abcd3 (ATP-binding cassette, sub-family D (ALD), member 3 [Source:MGI Symbol;Acc:MGI:1349216])

HSP 1 Score: 284.648 bits (727), Expect = 2.138e-86
Identity = 132/273 (48.35%), Postives = 183/273 (67.03%), Query Frame = 2
Query: 1286 SGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPAT-------NYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDEIK 2083
            + +T+R+ EL+ V  DL+   Y  T  + + +G    A+    VP         N I+   VP+ TPNGD+++ +LS  +  G ++LI GPNGCGKSSLFR+   LWP++GG+LT P +  ++++PQ+PY+ LGTLRDQ+IYPD     K +G++D+ L+E LD VQL  I+ REGG D  +DW++V SGGEKQR+ MARLFYHKPQFA+LDECTSAVS+DVE  IY    K+G+TL TV+HR SLWK H   L  DG G +    + +D ++
Sbjct:  275 NSFTARITELMQVLKDLNHGRYERTMVSQQEKGIEG-AQASPLVPGAGEIINTDNIIKFDHVPLATPNGDILIQDLSFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGKEDQKKRGISDQVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKKITEDTVE 546          

HSP 2 Score: 103.99 bits (258), Expect = 1.057e-22
Identity = 79/234 (33.76%), Postives = 124/234 (52.99%), Query Frame = 2
Query:  248 ENEGSK----VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNS 937
            E EG K    V+ +F  RL  +LKI+ P+   KE+  L +    L+ RT+  +++      I   I+ R    F   L  F+      + +N+F+++    L +CFR +L  Y Y+ Y +  TYY++ N+D RI N DQ LT+D+  F +S+  LYS L+KPFLD+ L  F L      +G     P  + A +++S G FL  +    G +   E K++G  R+V+SR+I NS
Sbjct:   49 EKEGKKERAVVDKVFLSRLSQILKIMVPRTFCKETGYLLLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSSKDFKRYLFNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTRYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQG-----PASMMAYLLVS-GLFLTRLRRPIGKMTIMEQKYEGEYRYVNSRLITNS 276          
BLAST of ATP-binding cassette sub-family D member 2 vs. UniProt/SwissProt
Match: sp|P33897|ABCD1_HUMAN (ATP-binding cassette sub-family D member 1 OS=Homo sapiens OX=9606 GN=ABCD1 PE=1 SV=2)

HSP 1 Score: 659.833 bits (1701), Expect = 0.000e+0
Identity = 322/602 (53.49%), Postives = 436/602 (72.43%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATG-RRNDGSFV-----DDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYR--------------VTNNAIEYQG----QSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            E+ LL +H+  L+ RTFLS+YVA LDG++ R IV++D   F  QLL++LLIALPATF+NS IR+LE +L++ FR++LV + Y+LYF  QTYYRV N+D R++N DQSLTED+  F++S+AHLYS LTKP LD+ + S++L + AR+RGA    P  IA  VV  T   LR  SPKFG LVAEEA+ KG LR++HSR++ NSEEIAFY GHEVE  +L ++YQ+L  Q N I L++LWYVM+EQFLMKYVWS++G+ MV++PI+TATG   +D   V     +   +  VSERT+ FT+ARNLL  +A A+ER+++SYKEVTEL+GYT+RVHE+  VF D+ +  ++              +  + +  +G    +  V  ++  +   N      +PIVTP+G+VVV  L++R+ +G H+LITGPNGCGKSSLFRI  GLWP YGG L  PP   M++IPQ+PY+ +G+LRDQ+IYPD++  M+ KG +++DL+ ILD+V L  I+ REGG +   DW +V SGGEKQRIGMAR+FYH+P++ALLDECTSAVSIDVE  I++ A   G+ LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   90 ETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFGWQLLQWLLIALPATFVNSAIRYLEGQLALSFRSRLVAHAYRLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQRSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYSESDAEAVKKAALEKKEEELVSERTEAFTIARNLLTAAADAIERIMSSYKEVTELAGYTARVHEMFQVFEDVQRCHFKRPRELEDAQAGSGTIGRSGVRVEGPLKIRGQVVDVEQGIICEN------IPIVTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYGGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHHILQREGGWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLD 685          
BLAST of ATP-binding cassette sub-family D member 2 vs. UniProt/SwissProt
Match: sp|Q9UBJ2|ABCD2_HUMAN (ATP-binding cassette sub-family D member 2 OS=Homo sapiens OX=9606 GN=ABCD2 PE=1 SV=1)

HSP 1 Score: 657.907 bits (1696), Expect = 0.000e+0
Identity = 344/623 (55.22%), Postives = 454/623 (72.87%), Query Frame = 2
Query:  248 ENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGG----VSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQS-NVAKLDDAVPATNYIE-----------LIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            E     VN+ FF++L  L KI+FPK ++ E+  LC+H+  L+ RTFLSIYVAGLDGKIV+SIV++    F+I+L+K+L+IA+PATF+NS IR+LE +L++ FRT+LV++ Y+ YF +QTYY+V N+D R+ N DQSLTEDI +FS S+AHLYS LTKP LD+ L S++L + A +RGAS   P ++A  VV +T + L+  SPKFG LVAEEA  KGYLR+VHSRII N EEIAFY GH+VE   L K+Y+ L  Q N I  ++LWY+MIEQFLMKYVWSS+G+ MV+IPI+TATG      F D + DG     VSERT+ FT ARNLL + A A+ER+++SYKEVTEL+GYT+RV+ +  VF ++ + +Y+ T    E +  S N AK++  +  T  I+              VPI+TP G+VV   L+ ++ +G H+LITGPNGCGKSSLFRI  GLWP+Y G L  PP   M++IPQ+PY+ LG+LRDQ+IYPD++  M +KG TD+DL+ IL  V L  I+ REGG D   DW +V SGGEKQR+GMAR+FYHKP++ALLDECTSAVSIDVE  I++ A   G++LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   74 EKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSYTLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMVAIPIITATG------FADGE-DGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLD 689          
BLAST of ATP-binding cassette sub-family D member 2 vs. UniProt/SwissProt
Match: sp|Q9QY44|ABCD2_RAT (ATP-binding cassette sub-family D member 2 OS=Rattus norvegicus OX=10116 GN=Abcd2 PE=1 SV=1)

HSP 1 Score: 657.522 bits (1695), Expect = 0.000e+0
Identity = 337/612 (55.07%), Postives = 446/612 (72.88%), Query Frame = 2
Query:  266 VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT------NNA-----IEYQGQSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            +N+ FF++L  L KI+FPK ++ E+  LC+H+  L+ RTFLSIYVAGLDGKIV+SIV++    F+I+L+K+L+IA+PATF+NS IR+LE +L++ FRT+LV++ Y+ YF +QTYY+V N+D R+ N DQSLTEDI +FS S+AHLYS LTKP LD+ L S++L + A +RGAS   P ++A  VV +T + L+  SPKFG LVAEEA  KGYLR+VHSRII N EEIAFY GH+VE   L K Y+ L  Q N I  ++LWY+MIEQFLMKYVWS  G+ MV+IPI+TATG   DG   D      VS+RT+ FT ARNLL + A A+ER+++SYKE+TEL+GYT+RV+ +  VF ++ + +Y+ T      NN+     +E      +A     +   + I    VPI+TP G+VV   L+ ++ +G H+LITGPNGCGKSSLFRI  GLWP+Y G L  PP   M++IPQ+PY+ LG+LRDQ+IYPD++  M  KG TD+DL+ IL  V L  I+ REGG D   DW +V SGGEKQR+GMAR+FYHKP++ALLDECTSAVSIDVE  I++ AI  G++LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   80 LNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLVKWLMIAVPATFVNSAIRYLECKLALAFRTRLVDHAYETYFANQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVILTSYTLIRTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGTLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKCYKALAYQMNLILSKRLWYIMIEQFLMKYVWSGCGLIMVAIPIITATGF-ADGDLEDGPKQAMVSDRTEAFTTARNLLASGADAIERIMSSYKEITELAGYTARVYNMFWVFDEVKRGIYKRTVTQEPENNSKSGGGLELPLSDTLAIKGTVIDVDHGILCENVPIITPAGEVVASSLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHEKGYTDRDLEHILHSVHLYHIVQREGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLD 690          
BLAST of ATP-binding cassette sub-family D member 2 vs. UniProt/SwissProt
Match: sp|Q61285|ABCD2_MOUSE (ATP-binding cassette sub-family D member 2 OS=Mus musculus OX=10090 GN=Abcd2 PE=1 SV=1)

HSP 1 Score: 657.522 bits (1695), Expect = 0.000e+0
Identity = 336/612 (54.90%), Postives = 444/612 (72.55%), Query Frame = 2
Query:  266 VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT-----------NNAIEYQGQSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            +N+ FF++L  L KI+FPK ++ E+  LC+H+  L+ RTFLSIYVAGLDGKIV+SIV++    F+I+L+K+L+IA+PATF+NS IR+LE +L++ FRT+LV++ Y+ YF +QTYY+V N+D R+ N DQSLTEDI +FS S+AHLYS LTKP LD+ L S++L + A +RGAS   P ++A  VV +T + L+  SPKFG LVAEEA  KGYLR+VHSRII N EEIAFY GH+VE   L K Y+ L  Q N I  ++LWY+MIEQFLMKYVWSS G+ MV+IPI+TATG   DG   D      VS+RT+ FT ARNLL + A A+ER+++SYKE+TEL+GYT+RV+ +  VF ++ + +Y+ T              +E      +A     +   + I    VPI+TP G+VV   L+ ++ +G H+LITGPNGCGKSSLFRI  GLWP+Y G L  PP   M++IPQ+PY+ LG+LRDQ+IYPD+   M+ KG TD+DL+ IL  V L  I+ REGG D   DW +V SGGEKQR+GMAR+FYHKP++ALLDECTSAVSIDVE  I++ AI  G++LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   80 LNAAFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFANQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVILTSYTLIRTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGSLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKCYKALAYQMNLILSKRLWYIMIEQFLMKYVWSSCGLIMVAIPIITATGF-ADGDLEDGPKQAMVSDRTEAFTTARNLLASGADAIERIMSSYKEITELAGYTARVYNMFWVFDEVKRGIYKRTVTQEPENHSKRGGNLELPLSDTLAIKGTVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQHMFYIPQRPYMSLGSLRDQVIYPDSADDMREKGYTDQDLERILHSVHLYHIVQREGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLD 690          
BLAST of ATP-binding cassette sub-family D member 2 vs. UniProt/SwissProt
Match: sp|D3ZHR2|ABCD1_RAT (ATP-binding cassette sub-family D member 1 OS=Rattus norvegicus OX=10116 GN=Abcd1 PE=1 SV=1)

HSP 1 Score: 649.432 bits (1674), Expect = 0.000e+0
Identity = 321/602 (53.32%), Postives = 426/602 (70.76%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGS------FVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQG------------------QSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            E+ LL +H+  L+ RTFLS+YVA LDG++ R IV++D   F  QLL++LLIALPATFINS IR+LE +L++ FR++LV + Y LYF  QTYYRV N+D R++N DQSLTED+  F++S+AHLYS LTKP LD+ + S++L + AR+RGA    P  IA  VV  T   LR  SPKFG LVAEEA+ KG LR++HSR++ NSEEIAFY GHEVE  +L  +YQ+L  Q N I L++LWYVM+EQFLMKYVWS++G+ MV++PI+TATG     S       ++   +  VSERT+ FT+ARNLL  +A A ER+++SYKEVTEL+GYT+RV+E+  VF D+    ++ T +  E Q                   Q  V  ++  +   N      +PI+TP G+VVV  L++R+ +G H+LITGPNGCGKSSLFRI  GLWP Y G L  PP   M++IPQ+PY+ +G+LRDQ+IYPD+   M+ KG +++ L+ IL IV L  I+ REGG +   DW +V SGGEKQRIGMAR+FYH+P++ALLDECTSAVSIDVE  I++ A   G++LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   91 ETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFSWQLLQWLLIALPATFINSAIRYLEGQLALSFRSRLVAHAYGLYFSQQTYYRVSNMDGRLRNPDQSLTEDMVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYAESDSEAMKKAALEMKEEELVSERTEAFTIARNLLTAAADATERIMSSYKEVTELAGYTARVYEMFQVFEDVQHCRFKRTGDLEEAQAGPGSMVHSGVHIEGPLKIQGQVVDVEQGIICEN------IPIITPTGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYSGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSAEDMRRKGCSEQQLEAILGIVHLRHILQREGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGISLLSITHRPSLWKYHTHLLQFDGEGGWKFEKLD 686          
BLAST of ATP-binding cassette sub-family D member 2 vs. TrEMBL
Match: A0A210PS41 (ATP-binding cassette sub-family D member 2 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT11773 PE=4 SV=1)

HSP 1 Score: 738.799 bits (1906), Expect = 0.000e+0
Identity = 365/615 (59.35%), Postives = 474/615 (77.07%), Query Frame = 2
Query:  266 VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTAT--GRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLD----------DAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKD 2074
            VN  F+++L+ LLKI+ P   +KE  +L VHT  L++RTFLSIYVA LDG+IV++IV+RDV  FL++L ++LLIA+PATF+NS IRFLE +L +  RT+LV++ YKLYF++QTYYRV+N+D R+ N DQ LT+DI++F+ SLAHLYS LTKP LD+ L++F+LY  A +RGAS + P ++A+ V+  T   LR++SPKFG LVAEEAK KGYLR+VHSR+I N+EEIAFY GH++E N+L  +Y+ L KQ + I   KLWY+M+EQFLMKYVWS++G+ MV+IPI++AT  G+R DGS VDDDPDGGV ERT+ FT ARNLL NSA A ER+I+SYKE+TEL+GYTSRV +++ VF D+    Y+   N +   G++    LD          + V   + I++  +PI+TPNGDV+V  L+L+I KG H+LITGPNGCGKSSLFRI  GLWP YGGKL  PP +TM++IPQ+PY+ LGT RDQ+IYPD L +M  KG TD DL+++LDIV L PI+ REGG D   DW +V SGGEKQR+GMAR+FYHKP FALLDECTSAVSIDVES IY+T    G++L+T+THRPSLWKFH  LL+FDGEGGW +  L+ +
Sbjct:   86 VNKRFYKQLRYLLKIVIPGLWTKEFGILTVHTLTLIVRTFLSIYVATLDGRIVQTIVKRDVKSFLLRLTEWLLIAIPATFVNSLIRFLECKLGLALRTRLVDHAYKLYFRNQTYYRVDNLDSRLANSDQCLTDDITMFTQSLAHLYSHLTKPLLDIALITFTLYSQASHRGASSKYPSMLASIVIFCTVHILRIVSPKFGKLVAEEAKRKGYLRYVHSRVIANAEEIAFYGGHKIEQNLLQTSYRHLAKQMDVIFKTKLWYIMLEQFLMKYVWSASGLVMVAIPIISATGGGKRTDGSHVDDDPDGGVGERTKAFTTARNLLINSADATERLISSYKEITELAGYTSRVSDMIEVFEDVGSGKYQ--RNTVTKVGKT--VALDHVSEPLEIKGEVVDTESTIDIQNLPIITPNGDVIVANLNLKIEKGTHLLITGPNGCGKSSLFRILSGLWPAYGGKLLKPPPSTMFYIPQRPYMSLGTFRDQVIYPDTLEEMVTKGYTDSDLEKVLDIVNLRPIVDREGGWDAHGDWKDVLSGGEKQRMGMARIFYHKPHFALLDECTSAVSIDVESKIYQTVKDSGISLMTITHRPSLWKFHTHLLQFDGEGGWRMEELDSN 696          
BLAST of ATP-binding cassette sub-family D member 2 vs. TrEMBL
Match: A0A0L8HEF7 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22016521mg PE=4 SV=1)

HSP 1 Score: 733.021 bits (1891), Expect = 0.000e+0
Identity = 360/604 (59.60%), Postives = 463/604 (76.66%), Query Frame = 2
Query:  266 VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPA-TNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKD 2074
            VN +FF +++ LLKI+ P   +KE  +L +HT  L+ RTFL+IYVA LDGKIV++IVQ+D  +F++QL K++ IA+PATF+NS IRF+E +L++  RT+LV+Y Y+ YF +QTYYRV N+DCR+ N DQ LT+DI+VFS SLAHLYS LTKP LD+ +M+F+LYKLARNRGAS RIP ++A  VV  T + LR +SP+FG L AEEAK KG LR++HSR+I N+EEIAFY GH +E + L + Y+ L    + I  ++LWY+M+EQFLMKYVWS+ G+ M +IPI+TATG + DG+ V+DDPDGGVSERTQ FT ARNLL ++A A ERM++SYKE+TEL+GYT RVH +L+VF D+ +  Y    N +     S + K+   V    N I +  +PI+TPNGDV+VPELSL I  G H+LITGPNGCGKSSLFRI  GLWP Y G L  PP   M++IPQ+PY+  G+LRDQ+IYP+ +  MK KG++DK+L+EIL IV L  I+ REGG D   DW +V SGGEKQR+GMARLFYHKPQFALLDECTSAVSIDVES+IY+ A   G+TLLT+THRP+LWKFH+ LL+FDGEGGW +  L+ D
Sbjct:   98 VNKVFFDQIRFLLKIVIPGIWTKEFGILSLHTLSLICRTFLTIYVASLDGKIVKTIVQKDAFEFMLQLSKWIGIAIPATFVNSLIRFVESKLALALRTRLVDYSYQKYFHNQTYYRVSNLDCRLTNADQCLTDDINVFSQSLAHLYSHLTKPLLDVAIMTFTLYKLARNRGASSRIPTLVAIVVVCVTAKVLRAVSPRFGKLAAEEAKRKGELRYMHSRVISNAEEIAFYGGHNIELSALQQCYRSLALHMDIIFRKRLWYIMLEQFLMKYVWSAAGLVMAAIPIITATGIKADGTCVNDDPDGGVSERTQSFTTARNLLISAADATERMMSSYKEITELAGYTERVHTMLSVFDDIKEEKY--VRNTVNDGRSSAILKIAGKVSDYDNGIFIEDLPIITPNGDVIVPELSLNITPGTHLLITGPNGCGKSSLFRILSGLWPAYRGTLKKPPTKHMFYIPQRPYMSRGSLRDQVIYPNTVGDMKAKGLSDKNLEEILSIVHLRHIVNREGGWDASNDWKDVLSGGEKQRMGMARLFYHKPQFALLDECTSAVSIDVESSIYQRAKDEGITLLTITHRPTLWKFHSHLLQFDGEGGWLMEVLDTD 699          
BLAST of ATP-binding cassette sub-family D member 2 vs. TrEMBL
Match: A0A2C9JCV4 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106054076 PE=4 SV=1)

HSP 1 Score: 729.169 bits (1881), Expect = 0.000e+0
Identity = 347/582 (59.62%), Postives = 456/582 (78.35%), Query Frame = 2
Query:  344 LLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDA-------VPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            +L +HT  L+IRTFLSIYVA LDG IV++IVQR+V +F++QL K++L+A+PATFINS IRFLE +L++ FRT+LV++ Y+ YF  QTYYRV N+D R+ N DQ LTEDI++F+SSLAHLYS LTKP LD+ LMSF+LY+LA++RGAS + P IIA  V++ T + LR +SPKFG LVAEEA  KG+LRF+HSRII N+EEIAFY+GH++E ++L + Y  L+KQ + I  ++LWY+M+EQFLMKYVWS++G+ MV++PI+TATG R DGS V+DD DGGVSERT+ FT ARNLL +SA A+ERM++SYKE+TEL+GYTSRV ++  VF D+    Y+      +   ++N  ++  +       +   + I +  +PI+TPNGD++V  LSL+I  G H+LITGPNGCGKSSLFRI +GLWP+YGGKL  PP  +M++IPQ+PY+ +GTLRDQ+IYPD++  MK KG+TD+DL  IL IV L+ I+ REGG   E DW +V SGGEKQR+GMAR FYH+P+FALLDECTSAVSIDVES IY +    G+TLLT+THRP+LWKFH  LL+FDGEGGW +  L+
Sbjct:  118 ILSLHTISLIIRTFLSIYVAQLDGSIVQTIVQRNVTRFVVQLAKWILLAVPATFINSLIRFLESKLALVFRTRLVKHAYEKYFDSQTYYRVSNLDSRLSNADQCLTEDITMFTSSLAHLYSHLTKPLLDVALMSFTLYRLAQSRGASSKTPTIIAMVVILITAKILRAVSPKFGKLVAEEAHRKGHLRFMHSRIITNAEEIAFYNGHQIERSLLTRCYSALVKQMDLIFYKRLWYIMLEQFLMKYVWSASGLIMVAVPIITATGIREDGSKVEDDDDGGVSERTRYFTTARNLLISSADAIERMMSSYKEITELAGYTSRVSQMFEVFEDVKLGKYQRNTVTKQKPIKTNFERISGSLVQKGVVIDTESTIIIENLPIITPNGDIIVQSLSLKIEDGMHLLITGPNGCGKSSLFRILNGLWPVYGGKLCKPPPTSMFYIPQRPYMSIGTLRDQVIYPDSVTDMKAKGITDEDLMNILKIVHLDNIVHREGGWQAECDWKDVLSGGEKQRMGMARTFYHRPKFALLDECTSAVSIDVESKIYLSLKAAGITLLTITHRPTLWKFHTHLLQFDGEGGWRMEELD 699          
BLAST of ATP-binding cassette sub-family D member 2 vs. TrEMBL
Match: A0A2T7NTT5 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_15039 PE=4 SV=1)

HSP 1 Score: 723.391 bits (1866), Expect = 0.000e+0
Identity = 366/628 (58.28%), Postives = 478/628 (76.11%), Query Frame = 2
Query:  218 LSNVNEMKTLENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVA---------KLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKD 2074
            + ++N  K+  N    VN LF+ +L+ LLKII P   SKE   L  HT  L+ RTFLS+YVA LDG+IV++IV+RDV KFL QL K+LL+A+PATFINS IRFLE +L++ FRT+LV + Y +YF  QTYY+V N+D R+ N DQ LTEDIS+F+ SLAHLYS LTKP LD+ L+SF+LY+LA +RGAS RIP  +A+ VV  T   LR++SPKFG LVAEEAK KG LRF+HSRII N+EEIAFYSGH+VE  +L ++Y  L  Q++ I L++LWY+M+EQFLMKYVWS++G+ MV++PILTATG R+DG+ VDDDPDGGVSERT+ FT ARNLL  SA A+ERM++SYKE+TEL+GYTSRV E+  VF D+    Y+   N +  + +S VA         +  + V     I++  +PI+TPNGD++VP L+L++  G H+LITGPNGCGKSSLFRI  GLWP+Y G+L  PP ++M++IPQ+PY+ +GTLRDQ+IYPD +  M+ KG+ D +L++I + V L+ I+ REGG D   DW +V SGGEKQR+GMAR+FYHKPQFALLDECTSAVSIDVES +Y++    G+TL+T+THRP+LWKFH  LL+FDGEGGW +  L+ +
Sbjct:   69 VDDINTKKSSPN----VNKLFYVQLRRLLKIIIPGVWSKEFGTLAFHTAILVTRTFLSVYVARLDGRIVKTIVERDVTKFLFQLTKWLLVAVPATFINSLIRFLENQLALVFRTRLVNHAYSMYFSDQTYYKVSNLDSRLTNADQCLTEDISMFTQSLAHLYSHLTKPLLDVALISFTLYQLANSRGASSRIPVAVASVVVFVTANILRIVSPKFGKLVAEEAKRKGNLRFIHSRIITNAEEIAFYSGHKVERMLLEQSYTSLAAQSSLIYLKRLWYIMLEQFLMKYVWSASGLIMVAVPILTATGVRSDGTRVDDDPDGGVSERTRAFTTARNLLIQSADAIERMMSSYKEITELAGYTSRVSEMFEVFEDVKNGNYK--RNTVT-KAKSKVAHERIEGPLLQKGEVVDTETTIDIKDLPIITPNGDIIVPSLTLKVETGMHLLITGPNGCGKSSLFRILSGLWPVYSGRLCKPPPSSMFYIPQRPYMSIGTLRDQVIYPDTVSDMQKKGVADSNLEDIFNTVHLQHIVHREGGWDAVSDWKDVLSGGEKQRMGMARIFYHKPQFALLDECTSAVSIDVESKMYQSLKDCGITLMTITHRPTLWKFHTHLLQFDGEGGWRMETLDTN 689          
BLAST of ATP-binding cassette sub-family D member 2 vs. TrEMBL
Match: A0A1I8GFG2 (ABC transporter domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027819g1 PE=4 SV=1)

HSP 1 Score: 716.072 bits (1847), Expect = 0.000e+0
Identity = 341/574 (59.41%), Postives = 441/574 (76.83%), Query Frame = 2
Query:  344 LLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNL 2065
            +L +HT  L+ RTFLS+YVA LDG+IV++IVQR+V +F++Q+ K+LL+ALPATF+NS IRFLE +L++  RT+LV + Y+ YFK QTYY+V N+D R++N DQ LTEDIS F+ SLAHLYS LTKP LD+ +MS++LY LAR+RGAS + P + A  V++ TGE LR +SPKFG LVAEEA+ KG LRF+HSR+I  +EEIAFY GH++E  VL  +Y+ L +Q++RI  Q+LWYVM+EQFLMKYVWS+ GM MV++PILTATG+R DGS VD+D DGGVSERTQ FT ARNLL ++A A+ER++TSYKE+TELSGYTSRV  +L VF+D+    + V       +GQ           + + IEL  VPIVTP+GDVV   LSLR+++G H+LITGPNGCGKSSLFRI  GLWP+YGG+L  PP  T+Y+IPQ+PYL +G LR+Q+ YPD   Q + KG+TD  L+ +L+   L  ++ REGG    ++W +V SGGEKQR+GMARL YH+P FALLDECTSAVSIDVE+ IY+ A   G+TLLT+THRPSLW FH+ +LKFDG G W+L  +
Sbjct:   99 ILLLHTTSLVTRTFLSVYVAKLDGRIVKAIVQRNVLRFVLQIAKWLLLALPATFVNSLIRFLESQLALALRTRLVMHCYQEYFKDQTYYKVGNLDSRLQNADQCLTEDISQFTGSLAHLYSHLTKPILDVAIMSYTLYSLARSRGASSKFPSVFATAVILFTGEVLRTVSPKFGRLVAEEARRKGRLRFIHSRVIACAEEIAFYGGHKLERRVLEDSYESLARQSSRIFRQRLWYVMLEQFLMKYVWSAAGMTMVAVPILTATGQRPDGSLVDEDQDGGVSERTQAFTTARNLLVSAADAIERIMTSYKEITELSGYTSRVSSMLNVFSDVQNGKF-VRPGMRHTRGQ--------VTESADCIELCDVPIVTPSGDVVAESLSLRLDRGTHLLITGPNGCGKSSLFRILSGLWPVYGGRLVKPPVQTLYYIPQRPYLSIGDLREQVTYPDTAEQRRAKGVTDGQLRAVLEAAHLGYLLEREGGWTAVREWADVLSGGEKQRLGMARLLYHRPLFALLDECTSAVSIDVEAKIYQAAKDAGITLLTITHRPSLWPFHDRVLKFDGAGAWSLEEM 663          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Cavefish
Match: abcd2 (ATP-binding cassette sub-family D member 2 [Source:NCBI gene;Acc:103029428])

HSP 1 Score: 672.929 bits (1735), Expect = 0.000e+0
Identity = 339/627 (54.07%), Postives = 452/627 (72.09%), Query Frame = 2
Query:  245 LENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYR---VTNNAIEYQGQSN----------------VAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            L+     VN+ F +++  L+KI+FPK +++E  LLC+H+  L+ RTFLSIYVAGLDG+IV++IV+++   F  +L+K+LL+A+PATF+NS IR+LE +L++ FRT+LVE+ Y+ YF  QTYY+V N+D R+ N DQSLTED+ +FS S+AHLYS LTKP LD+ L S++L + AR+RGA+   P ++A  VV  T + LR  SP+FG LVAEEA  KGYLR+VHSRII N+EEIAFY GH+VE   L K Y+ L +Q N I  ++LWY+M+EQFLMKYVWS  G+ MV++PI+TATG   D    D      VSERT+ FT ARNLL + A A+ER+++SYKEVTEL+GYT+RVH +  VF ++ + VY+   V+  A + + +S                 V  +D  +   N      VPI+TPNGDVVV  L+ ++ +G H+LITGPNGCGKSSLFRI  GLWP+YGG L  P    M++IPQ+PY+ +GTLRDQ+IYPD+L  M  KG  DKDL+ ILDIV L  I++REGG + E DW +V SGGEKQR+GMAR+FY +P++ALLDECTSAVSIDVE  I++ A   G++LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   61 LQPAAPGVNAEFMRQILALVKIVFPKLLTRELALLCLHSSALVSRTFLSIYVAGLDGQIVKTIVEKEPRSFAAKLIKWLLVAIPATFVNSAIRYLEGKLALAFRTRLVEHAYRTYFTEQTYYKVSNMDGRLANPDQSLTEDVMMFSQSVAHLYSNLTKPILDVILTSYTLIQTARSRGANATGPTLLAGLVVFVTAKVLRACSPRFGKLVAEEAHRKGYLRYVHSRIITNAEEIAFYRGHKVEMRQLQKCYKALAEQMNLILSKRLWYIMVEQFLMKYVWSGCGLVMVAVPIITATGF-ADNELADGQTQVLVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTARVHNMFLVFDEVQRGVYKRASVSTTAADGEKKSGGRHELHIDGPLEIKGKVIDVDKGIVCEN------VPIITPNGDVVVSSLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYGGLLYKPAPQHMFYIPQRPYMSVGTLRDQVIYPDSLEDMHEKGFRDKDLESILDIVNLNHIVSREGGWEAEVDWKDVLSGGEKQRMGMARMFYQRPKYALLDECTSAVSIDVEGKIFQAAKDAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLD 680          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Cavefish
Match: abcd1 (ATP-binding cassette sub-family D member 1 [Source:NCBI gene;Acc:103026406])

HSP 1 Score: 647.506 bits (1669), Expect = 0.000e+0
Identity = 337/635 (53.07%), Postives = 446/635 (70.24%), Query Frame = 2
Query:  224 NVNEMKTLENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATG-RRNDGSFVDD-----DPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQG-QSNVAKLD-------------DAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
             V E +  +     VN  F +RL  LL+I+FP+   KE  LL  H+  L+ RTFLSIYVA LDGKIV++IV++D   F+ +L K+LLIA+PATF+NS IR+LE +LS+ FRT+LV + Y+LYF  QTYYRV N+D R+ N DQSLTED+ +F++S+AHLYS LTKP LD+ +  ++L  + +++GA+   P +IA  VV  T + LR  SP+FG LVAEEAK KG LR++HSRII NSEEIAFY GH+VE + L ++Y+ L  Q N I  ++LWYVM+EQFLMKY+WS++G+ MV++PI+TATG   +D   V         +  VSERT+ FT ARNLL  +A AVER+++SYKEVTEL+GYT+RV+E+  VF D+   VYR +       G +S + ++                +     I    +PI+TP GDVVV  L++++++G H+LITGPNGCGKSSLFRI  GLWP+Y G L  PP   M++IPQ+PY+ +GTLRDQ+IYPD   +M  KG TD+ L+ IL  V L  I+ REGG D E DW +V SGGEKQR+GMAR+FYHKP++ALLDECTSAVSIDVE  I+E A   G+ LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   59 EVVERRRNKKSSPAVNREFLERLSRLLRILFPRLFCKELALLGFHSLALISRTFLSIYVANLDGKIVKTIVKKDPQAFVWELTKWLLIAIPATFVNSAIRYLEGQLSLAFRTRLVTHAYRLYFSDQTYYRVSNMDGRLANPDQSLTEDMVMFAASVAHLYSNLTKPILDVVMTCYTLINIGQSKGANTTWPSVIAGIVVALTAKILRAFSPRFGKLVAEEAKRKGDLRYMHSRIIANSEEIAFYGGHKVEMSQLQRSYKALHSQINLILFKRLWYVMLEQFLMKYLWSASGLVMVAVPIITATGYSEHDSEDVKQAAMVMKEEDLVSERTEAFTTARNLLNAAADAVERIMSSYKEVTELAGYTARVYEMFEVFEDVRVGVYRRSAEEERSGGTRSGLREVKHGMRVDGPLQIGGQVIDVDQGIRCESLPIITPTGDVVVSSLNIKVDEGMHLLITGPNGCGKSSLFRILSGLWPVYSGVLYKPPPQHMFYIPQRPYMSVGTLRDQVIYPDTTQEMVEKGFTDQQLEGILRTVNLLYILEREGGWDAESDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFEAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWRFEKLD 693          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Cavefish
Match: abcd3a (ATP binding cassette subfamily D member 3 [Source:NCBI gene;Acc:103023288])

HSP 1 Score: 409.068 bits (1050), Expect = 1.089e-132
Identity = 229/620 (36.94%), Postives = 357/620 (57.58%), Query Frame = 2
Query:  245 LENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPATNYIELI-------KVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDEIK 2083
            ++ + + V+ +FF R+  +++I+ P+   KE++ L +    L+ RT+  +++      I   I+ RD+  F      ++ +      +N+ ++F    L + FR +L ++ Y  Y K  TYY++ N+D RI N DQ LT+D+  F +S+  LYS L+KP LD+ L  F L      +G     P  + A ++IS G FL  +    G +   E K +G  R+V+SR+I NSEEIAFY+G+  E   +   +++L+   +     +    M++  + KY+ +  G   VS P L     R+  S          SE  + +  +  +L   + A+ R++ + +E+T LSG+T+R+ EL+ V  DL+   Y  T  ++  +    + KL   VP +  I  I         P+ TPNGDV++ +LS  +  G ++L+ GPNGCGKSSLFR+   LWP++GG LT P +  ++++PQ+PY+ LG+LRDQ+IYPD     K KG++D+ L+E LD VQL  I+ REG  D  +DW++V SGGEKQR+ MARLFYHKPQFA+LDECTSAVS+DVE  IY    K+G+TL TV+HR SLWK H   L  DG G ++   +  + ++
Sbjct:   47 VKKDRAAVDKVFFMRICRIVRIMVPRLFCKETWYLTMIAVMLVARTYCDVWMIQNGTMIESGIISRDITLFKRHFFSYITVIPWIALVNNLLKFGLNELKLRFRERLTKHLYDEYLKGYTYYKMGNLDNRIANADQLLTQDVERFCNSVVDLYSNLSKPLLDIGLYIFKLTTAIGAQG-----PATMMAYLLIS-GLFLTRMRRPIGKMTVTEQKFEGEYRYVNSRLITNSEEIAFYNGNVREKQTIHSTFKKLVDHLHNFIFFRFSMGMVDDIIAKYLATVVGYLSVSRPFLNLADPRHLNS--------THSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLSGFTTRITELMKVLKDLNSGKYERTMVSLSEKETDALEKLT-LVPGSGRIINIDNIIRFEHTPLATPNGDVLIRDLSFEVKSGTNVLVCGPNGCGKSSLFRVLGELWPLFGGSLTKPERGKLFYVPQRPYMTLGSLRDQVIYPDTYEDQKKKGISDQVLKEYLDNVQLGHILDREGSWDAVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYDFKPITSETVE 651          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Cavefish
Match: abcd3a (ATP binding cassette subfamily D member 3 [Source:NCBI gene;Acc:103023288])

HSP 1 Score: 405.986 bits (1042), Expect = 1.524e-131
Identity = 230/620 (37.10%), Postives = 357/620 (57.58%), Query Frame = 2
Query:  245 LENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPATNYIELI-------KVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDEIK 2083
            ++ + + V+ +FF R+  +++I+ P+   KE++ L +    L+ RT+  +++      I  +I+ R    F   L  F+ +      +N+ ++F    L + FR +L ++ Y  Y K  TYY++ N+D RI N DQ LT+D+  F +S+  LYS L+KP LD+ L  F L      +G     P  + A ++IS G FL  +    G +   E K +G  R+V+SR+I NSEEIAFY+G+  E   +   +++L+   +     +    M++  + KY+ +  G   VS P L     R+  S          SE  + +  +  +L   + A+ R++ + +E+T LSG+T+R+ EL+ V  DL+   Y  T  ++  +    + KL   VP +  I  I         P+ TPNGDV++ +LS  +  G ++L+ GPNGCGKSSLFR+   LWP++GG LT P +  ++++PQ+PY+ LG+LRDQ+IYPD     K KG++D+ L+E LD VQL  I+ REG  D  +DW++V SGGEKQR+ MARLFYHKPQFA+LDECTSAVS+DVE  IY    K+G+TL TV+HR SLWK H   L  DG G ++   +  + ++
Sbjct:   47 VKKDRAAVDKVFFMRICRIVRIMVPRLFCKETWYLTMIAVMLVARTYCDVWMIQNGTMIESAIIGRSTTDFKRYLFNFMRVMPVIALVNNLLKFGLNELKLRFRERLTKHLYDEYLKGYTYYKMGNLDNRIANADQLLTQDVERFCNSVVDLYSNLSKPLLDIGLYIFKLTTAIGAQG-----PATMMAYLLIS-GLFLTRMRRPIGKMTVTEQKFEGEYRYVNSRLITNSEEIAFYNGNVREKQTIHSTFKKLVDHLHNFIFFRFSMGMVDDIIAKYLATVVGYLSVSRPFLNLADPRHLNS--------THSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLSGFTTRITELMKVLKDLNSGKYERTMVSLSEKETDALEKLT-LVPGSGRIINIDNIIRFEHTPLATPNGDVLIRDLSFEVKSGTNVLVCGPNGCGKSSLFRVLGELWPLFGGSLTKPERGKLFYVPQRPYMTLGSLRDQVIYPDTYEDQKKKGISDQVLKEYLDNVQLGHILDREGSWDAVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYDFKPITSETVE 651          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Cavefish
Match: abcd4 (ATP-binding cassette, sub-family D (ALD), member 4 [Source:ZFIN;Acc:ZDB-GENE-050517-30])

HSP 1 Score: 217.624 bits (553), Expect = 4.854e-61
Identity = 162/538 (30.11%), Postives = 273/538 (50.74%), Query Frame = 2
Query:  503 FINSFIRFLEKR----LSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLT-KPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLR--LISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLW-YVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGG--KLTT--PPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLD--VEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKD 2074
             INS ++ +E+     L + +R  L E  ++ YF  + YY +  +   I N DQ +++D+      L+ + S+    PF     +S+  Y+   + G  I + CI    +V   G F    L+ P    LV +E     +  F H +I  N+E  AFY   +VE     +  Q L++   R+   +LW Y+ +  F   Y+ S     +++IPI +           D    G +S            L N  + +  + T+   V++++GYT R+ EL  V   + +      N  ++  G        D     NY  LI  P+   + +++V +LSLRI +G H+L+ G  G GK+SL R+ + LW    G  ++TT   P+  ++ +PQKPYL  GTLR+Q+IYP   I      + D+ +++ L++  +  ++ R GGLD  VE +W +V S GE QR+  ARLFY +P++A+LDE TSA++ + E  +Y T  ++GMTL++  HR +L K+H+++L+  G G W ++ ++ D
Sbjct:  123 LINSVVKSVEQYICSLLYVSWRKSLTEELHRDYFWGRVYYTLSVLRKDIDNPDQRISQDVERLCKQLSTMASRFVISPFT----VSYYTYQCFNSTGY-IGVLCIFGYFLV---GTFANKILMGPIVSTLVEQEKLEGDFRLFKHMQIRVNAESAAFYRAGKVEHMRTDQRLQSLLQTQKRLMKTELWLYIGVNTF--DYLGSILSYIVIAIPIFSGV--------YDGMTPGELSALVSRNAFVCIYLINCFTQLIDLSTT---VSDVAGYTHRIGELREVMRSVGRKQCEC-NPVLKETGDF------DRYTVLNY--LISSPV---SEELLVKDLSLRICQGSHLLLVGNTGTGKTSLLRVLNCLWEPSNGCVEMTTFFGPRGILF-LPQKPYLTDGTLREQVIYPLKDIYPAAGSVDDERIKQYLELAGVSSLLKRTGGLDEKVEWNWYDVLSPGEMQRLCFARLFYLQPKYAVLDEATSALTEEAEGQMYRTCKQLGMTLISSGHRSTLEKYHDVMLRLCGGGQWEITKIKSD 626          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Sea Lamprey
Match: abcd1 (ATP-binding cassette, sub-family D (ALD), member 1 [Source:NCBI gene;Acc:566367])

HSP 1 Score: 267.7 bits (683), Expect = 3.158e-84
Identity = 118/196 (60.20%), Postives = 151/196 (77.04%), Query Frame = 2
Query: 1484 PELSL-RINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            P  SL ++ +G H+LITGPNGCGKSSLFRI  GLWP+Y G L  P  + +++IPQ+PY+ +GTLRDQ+IYPD    M+ KG TD  L+ I+DIV L  +I REGG D + DW +V SGGEKQR+GMAR+FYH+P++ALLDECTSAVSIDVE  I++ A   G++LL++THRPSLWK+H  LL+FDGEGGW    L+
Sbjct:   14 PHCSLEQVEQGMHLLITGPNGCGKSSLFRILSGLWPVYHGSLYKPAPHYLFYIPQRPYMSIGTLRDQVIYPDQPADMQRKGYTDTTLEAIMDIVNLNHVIRREGGWDAKSDWKDVLSGGEKQRMGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDGGISLLSITHRPSLWKYHTHLLQFDGEGGWMFEQLD 209          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Sea Lamprey
Match: abcd4 (ATP-binding cassette, sub-family D (ALD), member 4 [Source:ZFIN;Acc:ZDB-GENE-050517-30])

HSP 1 Score: 237.654 bits (605), Expect = 3.827e-69
Identity = 168/539 (31.17%), Postives = 269/539 (49.91%), Query Frame = 2
Query:  506 INSFIR----FLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLW-YVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVF---TDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPATNYIELIKVPIVTPNG-DVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGG----KLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWI--NVFSGGEKQRIGMARLFYHKPQFA-LLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKD 2074
            INSF++    ++   L + +R  + E+ + LYF+ + YYR+  +   + N DQ +++D+  F   L+ + S+L      LC  ++  +      G     P  + A  ++ T     L+ P    LVA+E K +G  RF H  I  N+E  AFY    VE          L+     +  ++ W Y+ +  F   Y+ S     +++IPI         G +    P    SE + + +    +     +   ++I    ++++++GYT R+ EL  V    TD     +  T  A  +  +S +   D+   A +   L  V   TP+G + +V +LSL++  G +IL+ G  G GK++L R+ +GLWP   G    +    P+  ++ +PQKPY   GTLR+Q+IYP   +    +   DK +   LD V L  ++ R GGLD E DW   +  S GE QR+  ARLFYH+P +A +LDE TSA++ DVE  +Y    ++GMT+L+V HR SL KFH+ +LK  G+G W L  L  D
Sbjct:   80 INSFLKSCDQYVSSLLYLTWRRSVTEHLHDLYFRGRAYYRLNTLQDALDNPDQRISQDVERFCKQLSLMASKLLISPFTLCYYTYQCFISTGWIG-----PVSVFAYFLVGTVTNKLLMGPIISTLVAQE-KMEGDFRFKHMEIRVNAESAAFYRAGRVEHTRTNARLHRLLSTQQTLMNKEFWLYLAVNMF--DYMGSILSYVVIAIPIFA-------GVYDHLSP----SELSALVSKNAFVCIYLINCFSQLIDLSSKLSDVAGYTHRIGELQEVLLEPTDAPNDKWDPTREA-SWDFESVIEAWDEV--AKDAFVLDCVSYSTPSGTEALVQDLSLQVAWGQNILVVGNTGTGKTTLLRVLNGLWPTLKGSVHMRTCFGPRGIIF-LPQKPYFTDGTLREQVIYPLKEMYPVTEDFDDKRILHFLDCVGLSALLDRTGGLDQEVDWSWSDALSPGEMQRLTFARLFYHQPTYAEVLDEATSALTEDVEGEMYRMCKQLGMTVLSVGHRSSLEKFHDSILKLCGKGRWELQTLFHD 595          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Sea Lamprey
Match: abcb6b (ATP-binding cassette, sub-family B (MDR/TAP), member 6b [Source:ZFIN;Acc:ZDB-GENE-070912-584])

HSP 1 Score: 67.3958 bits (163), Expect = 5.828e-12
Identity = 58/207 (28.02%), Postives = 88/207 (42.51%), Query Frame = 2
Query: 1433 IELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLT--------TPPKNTMYHI---PQKPYLFLGTLRDQIIY-----PDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKM--GMTLLTVTHRPS 1999
            +E   V     NG  ++  +S  +  G  I + GP+G GKS++ R+    + +  G ++           K+   HI   PQ   LF  T+R+ I Y      D  ++   +     D   IL   +       E GL +        SGGEKQR+ +AR     P+  LLDE TSA+    E NI  +  K+    T + + HR S
Sbjct:  206 VEFDNVSFNYVNGKDILKNVSFTVPSGKTIALVGPSGAGKSTVMRLLFRFYDVKSGCISIDGQDISKVKQKSLRQHIGVVPQDTVLFNDTIRNNIRYGRVTASDEEVEEAARAADIHD--RILSFPEGYNTQVGERGLKL--------SGGEKQRVAIARTILKAPELILLDEATSALDTQTERNIQASLAKICANRTSVVIAHRLS 402          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Sea Lamprey
Match: ABCB1 (ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40])

HSP 1 Score: 67.781 bits (164), Expect = 7.394e-12
Identity = 51/201 (25.37%), Postives = 91/201 (45.27%), Query Frame = 2
Query: 1478 VVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNT-----------MYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQL-EPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKM--GMTLLTVTHRPSLWKFHNLLLKFDG 2038
            V+  ++L++  G  + + G +GCGKS+  ++    +    G +    ++            +  + Q+P LF  T+ + I +    + M++     ++      I Q+ E   T  G      D     SGG+KQRI +AR     P+  LLDE TSA+  + E+ + E   K   G T + + HR S  +  +++  FDG
Sbjct:  195 VLKGVNLQVKSGQTVALVGSSGCGKSTTIQLLQRFYDPQQGTIMVDGRDVRTLNLRSLRQLIGVVSQEPVLFATTIAENIRFGHEKVTMEDIERAARNANAYDFISQMPERFNTLVG------DRGAQLSGGQKQRIAIARALIRNPKLLLLDEATSALDGESEAIVQEALDKAREGRTTIVIAHRLSTIRNADIIAGFDG 389          

HSP 2 Score: 67.3958 bits (163), Expect = 1.014e-11
Identity = 57/198 (28.79%), Postives = 89/198 (44.95%), Query Frame = 2
Query: 1463 PNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNT-----------MYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEK------DWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYET--AIKMGMTLLTVTHRPS 1999
            PN +V+   LSL++  G  + + G +GCGKS+  ++    +    G +    K+            M  + Q+P LF  ++ + I Y DN        +  +D  EI+   +   I T    L  EK      D     SGG+KQRI +AR    +P+  LLDE TSA+  + E  + E     + G T + + HR S
Sbjct:  831 PNVEVL-KGLSLKVENGQTLALVGSSGCGKSTSVQLLERFYDTLSGNVLIDGKDVRSLHIQWLRAQMGIVSQEPVLFDCSMAENIAYGDN------SRIVPQD--EIVAAARAANIHTFIDSLP-EKYNTKVGDKGTQLSGGQKQRIAIARALVRQPKILLLDEATSALDTESEKIVQEALDRAREGRTCIVIAHRLS 1018          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007076.1 (pep scaffold:Pmarinus_7.0:GL480539:10051:22495:1 gene:ENSPMAG00000006379.1 transcript:ENSPMAT00000007076.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.4698 bits (158), Expect = 2.285e-11
Identity = 50/185 (27.03%), Postives = 87/185 (47.03%), Query Frame = 2
Query: 1490 LSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKL-----------TTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKG-MTDKDLQEILDIVQLEPIITREGGLDVE-KDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIK--MGMTLLTVTHRPS 1999
            +S  IN  + + I G  G GKS+LF +   +  +  G +               ++ +  IPQ P+LF  T+R+          +  KG   D +L E+L+   L+  +  +GGL  E  +    FS G++Q + +AR    K +   +DE T++V  D +  + +T     +  T+LT+ HRP+
Sbjct:  320 ISFCINSWEKVGIVGRTGSGKSTLFSVLFRIVDVQHGAIYIDNQDISKLALKQLRSNLAIIPQDPFLFSDTVRN---------NLDPKGSYQDHELWEVLEKCHLKSFVLDQGGLQAEVAERGRDFSCGQRQLLCLARAMLFKAKILCIDEATASVDQDTDVLLQKTIRSEFVNSTVLTIAHRPN 495          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Yeast
Match: PXA1 (Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p; required for import of long-chain fatty acids into peroxisomes; similar to human adrenoleukodystrophy transporters ABCD1and ABCD2, and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; human ABCD1 and ABCD2 can each partially complement yeast pxa1 pxa2 double null mutant [Source:SGD;Acc:S000006068])

HSP 1 Score: 305.834 bits (782), Expect = 3.187e-92
Identity = 215/653 (32.92%), Postives = 341/653 (52.22%), Query Frame = 2
Query:  341 FLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYF-KHQTYYRV----ENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVIS---TGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQI--FTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVF---------------------------------TDLSQSVYRVT----NNAIEYQGQSNVAKLDDAVPATNYIELI-----KVPI--------------VTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYG--GKLTTPPKNTMYHIPQKPYLFLG-TLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGL---DVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKF--DGEGGWNLSNLEKDE 2077
             LL    F L++RT+LS++VA LDG+IV++I+      FL  L  + LIA+PA++ NS I+ L+++LS+ FR  L  Y + +Y  K  T+Y++    +  +  IKN+D S+T D++ F  +   +++ + KP +DL    FS+Y L  N G       +  AG+ ++   TG  LR  +P  G L  E +   G     H  +I NSEEIAFY G  VE   + + Y  L+++   +   K  Y M+E +++KY WS  G    SIPI+ +T              G  SE   +  F + + L+ + A A  R++ S K++++L+GYT+R+  LL+V                                  TD SQ   R T     N I  +   N+  +  +V A+  I+LI     ++P+              ++   D+ +P L      G  +LI GPNGCGKSS+ RI   +WP+Y   G L+ P +N ++ IPQKPY   G TLRDQIIYP +  +  ++G  DK+L +IL  V+L+ ++ R  GL   D   DW ++ SGGEKQR+  AR+ +HKP + +LDE T+A+S+D+E  ++    +     ++++ RP+L K+H +LL+   + +G W L  +  DE
Sbjct:  208 LLLTAQIFFLVMRTWLSLFVAKLDGQIVKNIIAGRGRSFLWDLGCWFLIAVPASYTNSAIKLLQRKLSLNFRVNLTRYIHDMYLDKRLTFYKLIFDAKASNSVIKNIDNSITNDVAKFCDATCSVFANIAKPVIDLIF--FSVY-LRDNLG------TVGVAGIFVNYFITGFILRKYTPPLGKLAGERSASDGDYYNYHLNMINNSEEIAFYQGTAVERTKVKELYDVLMEKMLLVDKVKFGYNMLEDYVLKYTWSGLGYVFASIPIVMSTL-----------ATGINSEEKNMKEFIVNKRLMLSLADAGSRLMHSIKDISQLTGYTNRIFTLLSVLHRVHSLNFNYGAVPSILSIRTEDASRNSNLLPTTDNSQDAIRGTIQRNFNGIRLE---NIDVIIPSVRASEGIKLINKLTFQIPLHIDPITSKSNSIQDLSKANDIKLPFLQ---GSGSSLLILGPNGCGKSSIQRIIAEIWPVYNKNGLLSIPSENNIFFIPQKPYFSRGGTLRDQIIYPMSSDEFFDRGFRDKELVQILVEVKLDYLLKRGVGLTYLDAIADWKDLLSGGEKQRVNFARIMFHKPLYVVLDEATNAISVDMEDYLFNLLKRYRFNFISISQRPTLIKYHEMLLEIGENRDGKWQLQAVGTDE 834          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Yeast
Match: PXA2 (Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p; required for import of long-chain fatty acids into peroxisomes; similar to human adrenoleukodystrophy transportesr ABCD1 and ABCD2, and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; human ABCD1 and ABCD2 can each partially complement yeast pxa1 pxa2 double null mutant [Source:SGD;Acc:S000001671])

HSP 1 Score: 303.523 bits (776), Expect = 1.698e-91
Identity = 203/621 (32.69%), Postives = 326/621 (52.50%), Query Frame = 2
Query:  344 LLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRD-VHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYF-KHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVI-STGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPI-------YGGKLTTPPKN-----TMYHIPQKPYL-FLGTLRDQIIYPDNLIQMKNK-----GMTDKDLQEILDIVQLEPIITREGGL-------------------------------DVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGW 2050
            L       L IRT LS+ VA LDG++V ++V+    +   I L K++++ +PA+FINS I +  K  ++    K+ ++    Y   H T+Y V + +  +  +  +LT+DI  FS + + L +QL KP LDL L SF L  L  N   S+     +A G+++ ++   L+LI P F  L    A  + + R +HS +  ++EEIA   G + E   +  ++  L+   NR    +  Y +   F++KY W + G+ + SIPI        D +    +P   +   T  F   R LL  ++S++ R +   + + +L G   R+++    F DL  +     ++  E + +  + + DD+      I+   +P++TP   V+VPELS  +  G+H+LI GPNGCGKSSLFRI  GLWPI       +  KL  P +       ++++PQ+PY+    T R+QIIYPD++ Q K +      + D DL +IL ++ LE ++T    L                                + ++W    + G +QR+ MAR++YHKP+FA+LDECTSAV+ ++E  +YE A   G++L++V HR SLW FHN LLKFDG+GG+
Sbjct:  126 LFITQAILLNIRTLLSLRVATLDGQLVSTLVRAQYANFTKILLGKWMILGIPASFINSLISYTTKLCAVTINRKVSDFLLSKYLSNHHTFYSVASAES-VSEIQDNLTKDIYTFSMNSSLLLNQLLKPMLDLILCSFKL--LTSN--TSVMGEGTLALGLIVYASNSLLKLIQPNFTRLTMASASLESWFRSLHSNLHSSNEEIALLRGQKRELENVDYSFYRLVLFLNREIKARAIYDVATAFVIKYTWGAAGLVLCSIPIFFKNKPSED-TLQLKEPGNDM---TADFITNRRLLVTASSSIGRFVELKRNIQQLRGIRLRLNK----FNDLLDA--NKGDDEKEPRDERCIVEYDDS-----RIKFENIPLITPANQVLVPELSFDLKHGNHLLIIGPNGCGKSSLFRILGGLWPIRATPNKNHQSKLIMPRRTVDRDCAIFYLPQRPYMGNRSTFREQIIYPDSIEQFKERYHNDYDLGDADLIKILQLLDLEDLVTENMSLLLAQRTSKNDSQQLSTEDNQSPCAIKVRDAFSIVRNWSEELTIGVQQRLAMARMYYHKPKFAVLDECTSAVAPEMEQRMYENAQNFGISLISVCHRTSLWHFHNYLLKFDGKGGY 726          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Yeast
Match: STE6 (Plasma membrane ATP-binding cassette (ABC) transporter; required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells; human homolog ABCB1 mediates multidrug resistance in many chemotherapy-resistant tumors by effluxing toxic compounds from the cell [Source:SGD;Acc:S000001692])

HSP 1 Score: 68.9366 bits (167), Expect = 2.028e-12
Identity = 55/188 (29.26%), Postives = 89/188 (47.34%), Query Frame = 2
Query: 1511 GDHILITGPNGCGKSSLFRIFHGLWPIYGGKLT-----------TPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQ-EILDIVQL----EPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMG---MTLLTVTHRPSLWKFHN 2017
            G  + I G +G GKS+L  +   L+    GK+            T  +  +  + QKP LF GT+RD + Y          G+ D+ L+ E+ D ++     + +I+   GLD   D   + SGG+ QR+ +AR    K +  +LDECTSA+   V S+I    +K G   +  + +TH   + +  N
Sbjct: 1080 GQTLGIIGESGTGKSTLVLLLTKLYNCEVGKIKIDGTDVNDWNLTSLRKEISVVEQKPLLFNGTIRDNLTY----------GLQDEILEIEMYDALKYVGIHDFVISSPQGLDTRID-TTLLSGGQAQRLCIARALLRKSKILILDECTSALD-SVSSSIINEIVKKGPPALLTMVITHSEQMMRSCN 1255          

HSP 2 Score: 53.1434 bits (126), Expect = 1.389e-7
Identity = 56/214 (26.17%), Postives = 88/214 (41.12%), Query Frame = 2
Query: 1421 ATNYIELIKVPIVTPN--GDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKN-----------TMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEP----IITREGGLDVEKDWINV-FSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAI---KMGMTLLTVTHRPS 1999
            AT+ +    V    P+   + V+  +SL  + G    I G +G GKS+L  +    +  Y G ++    N            +  + Q+  LF  TLR  I+             T+++   I D  Q+      I+    GL+       V  SGG++QR+ +AR F        LDE  SA+ I V  N+   AI   + G T + +TH  S
Sbjct:  353 ATSDLTFANVSFSYPSRPSEAVLKNVSLNFSAGQFTFIVGKSGSGKSTLSNLLLRFYDGYNGSISINGHNIQTIDQKLLIENITVVEQRCTLFNDTLRKNILLGSTDSVRNADCSTNENRHLIKDACQMALLDRFILDLPDGLETLIGTGGVTLSGGQQQRVAIARAFIRDTPILFLDEAVSALDI-VHRNLLMKAIRHWRKGKTTIILTHELS 565          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Yeast
Match: MDL1 (Mitochondrial inner membrane half-type ABC transporter; mediates export of peptides generated upon proteolysis of mitochondrial proteins; plays a role in the regulation of cellular resistance to oxidative stress [Source:SGD;Acc:S000004178])

HSP 1 Score: 68.5514 bits (166), Expect = 2.406e-12
Identity = 58/224 (25.89%), Postives = 97/224 (43.30%), Query Frame = 2
Query: 1433 IELIKVPIVTPNGDVVVP---------ELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNT-----------MYHIPQKPYLFLGTLRDQIIY---------PDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAV---SIDVESNIYETAIKMGMTLLTVTHRPSLWK 2008
            + L + PIV  N     P         +L++ I  G+H+   GP+G GKS++  +    + +  G +    ++            + ++ Q+P LF GT+ D I+Y          D + +   K    K L    D +Q     T  G    +       SGG+KQRI +AR F   P   +LDE TSA+   S ++ +   +  ++ G T +++ HR S  K
Sbjct:  425 VSLAQKPIVFKNVSFTYPTRPKHQIFKDLNITIKPGEHVCAVGPSGSGKSTIASLLLRYYDVNSGSIEFGDEDIRNFNLRKYRRLIGYVQQEPLLFNGTILDNILYCIPPEIAEQDDRIRRAIGKANCTKFLANFPDGLQ-----TMVGARGAQ------LSGGQKQRIALARAFLLDPAVLILDEATSALDSQSEEIVAKNLQRRVERGFTTISIAHRLSTIK 637          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Yeast
Match: MDL2 (Mitochondrial inner membrane half-type ABC transporter; required for respiratory growth at high temperature; localizes to vacuole membrane in response to H2O2; similar to human TAP1 and TAP2 implicated in bare lymphocyte syndrome and Wegener-like granulomatosis [Source:SGD;Acc:S000006191])

HSP 1 Score: 66.2402 bits (160), Expect = 1.286e-11
Identity = 71/276 (25.72%), Postives = 118/276 (42.75%), Query Frame = 2
Query: 1232 SASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSV---YRVTNNAIEYQGQSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTP--------PKNTMYHI---PQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGL--DVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKM----GMTLLTVTHRPS 1999
            + +AV  + T Y E+ + +G  SR+ EL      +S +V   Y+     IE++  S       + P    +++ K              L+ +I  G  + I GP+G GKS++  +    +    G +T           K+   HI    Q+P L  GT+RD I Y       K      ++++ +         IT+       V      + SGG+KQRI +AR    KP   +LDE TSA+ ++ E  I  T  ++     MT++++ HR S
Sbjct:  397 TGNAVFGLSTFYSEIMQGAGAASRLFELTDRKPSISPTVGHKYKPDRGVIEFKDVSF------SYPTRPSVQIFK-------------NLNFKIAPGSSVCIVGPSGRGKSTIALLLLRYYNPTTGTITIDNQDISKLNCKSLRRHIGIVQQEPVLMSGTIRDNITYGLTYTPTK------EEIRSVAKQCFCHNFITKFPNTYDTVIGPHGTLLSGGQKQRIAIARALIKKPTILILDEATSALDVESEGAINYTFGQLMKSKSMTIVSIAHRLS 647          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Nematostella
Match: EDO37138 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGR3])

HSP 1 Score: 641.728 bits (1654), Expect = 0.000e+0
Identity = 320/590 (54.24%), Postives = 425/590 (72.03%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQS--VYRVTNNAIEYQGQSNVAKLDDAV-----------PATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNL 2065
            ++ LL VH+ CL+ RTFLSIYVA LDG++++SIVQ++V  F++QLLK++ +A+PATFINS IRFLE R+++ FRT+LV + Y+ YF +QTYY+V N+D R+ N D+ LTEDI +F +S+AHLYS LTKP LD+ ++ ++L  +AR RGAS ++P  IA  V+  T   LR +SPKFG + AEE+K +G LRF+HSR+I NSEEIAFY GH+VE + L  ++Q L KQ  RI  Q+LWY+M+EQFLMKYVWS+ G+ MV+  IL       +   ++   D GVS R Q  T +R+LL ++A A+ER+++SYKE+TELSGYT RV E+L+VF DL +   +   T +  +    S+ AK+   V                I L  V ++TP GDVVV  L+  +  G H+LITGPNGCGKSSLFRI  GLWP+Y G L  PP + M++IPQ+PY+ +G+LRDQ+IYPD    M  KG+TDKDL+EIL  V L+ II REGG D  K+W +VFSGGEKQR+GMARLFYHKPQFALLDECTSAVSIDVE +I++ A   G+TLL+++HRPSLWK+H  +L+FDGEGGW    L
Sbjct:   96 QAGLLFVHSGCLIARTFLSIYVATLDGRVIKSIVQKNVPMFIVQLLKWIAVAIPATFINSMIRFLENRIALSFRTELVNHAYEKYFANQTYYKVGNLDNRLTNADECLTEDIRMFCNSIAHLYSHLTKPCLDIVVICWTLDSMARKRGASWKLPLSIAGVVIYLTAMILRSMSPKFGRMAAEESKRRGQLRFLHSRVIANSEEIAFYGGHKVELSWLRNSFQSLAKQMERIYSQRLWYIMLEQFLMKYVWSAAGLVMVATQILVGQATPEE---LESGSDNGVSSRAQQITTSRHLLVSAADAIERIMSSYKEITELSGYTQRVFEMLSVFEDLEKGHCIRSSTADQSKENLNSHHAKVGQVVNLKQMPGGAVEDTEGTITLRDVAVITPCGDVVVSSLAFEMQPGMHLLITGPNGCGKSSLFRILSGLWPVYKGYLAKPPPSHMFYIPQRPYMPIGSLRDQVIYPDREEDMTAKGLTDKDLEEILSTVYLQNIIKREGGWDTVKEWKDVFSGGEKQRMGMARLFYHKPQFALLDECTSAVSIDVEGSIFQAAKDSGITLLSISHRPSLWKYHTHILQFDGEGGWKYEQL 682          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Nematostella
Match: EDO33705 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRG2])

HSP 1 Score: 397.512 bits (1020), Expect = 2.663e-128
Identity = 221/594 (37.21%), Postives = 336/594 (56.57%), Query Frame = 2
Query:  347 LCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPD---GGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT----NNAIEYQGQSNVAKLD---------DAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDEI 2080
            L +    L+ RT+  +++      I RSI+  +   F   LL  +        +N  +++    L + FR +L  +  K Y    TYY++ N+D RI N DQ LT+D+  F + LA LYS ++KPFLD+ +    L      +G SI +  +  +G V++     RL  P  G +  +E   +G  R+V+SR+I NSEEIAFY G++ E   +  ++  L+         +    +++  + KY+ +  G ++VS P LT           DD+P       S R + +  +  +L   A A+ R++ + +E+T L+G+T+RV EL  V  DL+   Y+ T       ++    + V K+          + V   + I    VP+VTPNGDV+V +++  +  G ++L+ GPNGCGKSSLFRI   LWP++ GKL  P  + +++IPQ+PY+ LGTLRDQ++YPD     + KG++DK L+E L  VQL  I+ REGG D  +DW++V SGGEKQRI MARLFYH+PQFA+LDECTSAVS+DVE  +Y    ++G+TL TV+HR SLWK+H  +L  DG G +  S ++   I
Sbjct:  113 LSLVALSLIARTYCDVWMIHNGTVIERSIITSNYDGFKENLLHLVCSMPLIALVNQLLKYGLNMLKLLFRDRLTMHLTKQYLSGFTYYKMSNLDNRIANADQLLTQDVDKFCACLADLYSNVSKPFLDIVIYVHKLSGAIGLQGPSIMLAYLAISGFVLT-----RLRRP-VGRMTVQEQHLEGEFRYVNSRLITNSEEIAFYQGNKREQLTIRSSFDRLMCHLKDFVQFRFIMGIVDNIIAKYLATVCGFYVVSRPFLT-----------DDNPQLRSSSHSVRMEDYYRSGRMLVKMAEAIGRLVLAGREMTRLAGFTARVSELTDVLKDLNSGKYQRTLISSRRPVDESEVTGVKKVSVEELTRSRGEMVETDHLIRFEHVPLVTPNGDVLVDDMTFEVRSGMNVLVCGPNGCGKSSLFRILGELWPLFSGKLVKPHPSKLFYIPQRPYMTLGTLRDQVVYPDTEADQRRKGISDKALEEFLTQVQLSYILDREGGWDTIQDWMDVLSGGEKQRIAMARLFYHQPQFAILDECTSAVSVDVEGFMYTRCREVGITLFTVSHRKSLWKYHEYVLYMDGRGSYQYSPMDSTTI 689          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Nematostella
Match: EDO29028 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4T4])

HSP 1 Score: 203.756 bits (517), Expect = 2.640e-61
Identity = 92/140 (65.71%), Postives = 113/140 (80.71%), Query Frame = 2
Query: 1646 KPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNL 2065
            +PY+ +G+LRDQ+IYPD    M  KG+TDKDL+EIL  V L+ II REGG D  K+W +VFSGGEKQR+GMARLFYHKPQFALLDECTSAVSIDVE +I++ A   G+TLL+++HRPSLWK+H  +L+FDGEGGW    L
Sbjct:    9 RPYMPIGSLRDQVIYPDREEDMTAKGLTDKDLEEILSTVYLQNIIKREGGWDTVKEWKDVFSGGEKQRMGMARLFYHKPQFALLDECTSAVSIDVEGSIFQAAKDSGITLLSISHRPSLWKYHTHILQFDGEGGWKYEQL 148          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Nematostella
Match: EDO39538 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9T9])

HSP 1 Score: 185.652 bits (470), Expect = 3.188e-50
Identity = 149/543 (27.44%), Postives = 257/543 (47.33%), Query Frame = 2
Query:  512 SFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQL-TKPFLDLCLMSFSLYKLARNRG--ASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFL------MKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPATNYIELIKVPIVTPNGDV-VVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLT-----TPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKD----LQEILDIVQLEPIITREGGLD--VEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDE 2077
            S ++++     + +R  L  + +  YF  +T+Y +  ++  I N DQ +T+D+  F    + + S L   PF     +++  Y+   + G    + I      G +I+     RLI      LV  + K +G  RF H ++  NSE +AFY   E+E     K    L+    ++       V  E FL        YV +     +++I +         G +    P     E ++   ++  L+G       ++I     V++++GY  R+ EL+       +S+ R      E Q    +  + + +     I+L  +    PN    +V +L+L I+ G ++LITG  G GKSSL R+   LW    G +T     TP K  +  +PQ+  L  G+L+ Q+IYP  +   ++   T ++    + ++LD V L  +  R GG++  ++ +W ++ S GE QR+  ARLFYH P  A+LDE TSA+ +  E ++Y    ++GMTL+++ HR SL  +H++ LK  G G W LS  + D+
Sbjct:   97 SIVQYVSNFSYVKWRGLLTRFLHTGYFHKETHYNLNVLERTIDNPDQRITQDVDRFCKQFSQIISSLLISPFT----IAYYTYQCYSSTGYLGPVSIFGYFLLGTIIN-----RLIMSPIINLVVRQEKLEGDFRFKHMQVRVNSEALAFYRSGELEQKKTNKRLHYLLNVQQKL-------VNFEFFLNFSVNFFDYVGAILSYIIIAIALFA-------GKYDSLSPTSLSGEISKNSFVSMYLIG----CFTKLIDLSNSVSDMAGYAHRIGELI-------ESLERKEEFRRESQ---ELNGIQNGIEPAVMIKLTDLTYGAPNSKSPLVKDLTLDISLGKNLLITGSTGTGKSSLLRVIRELWMPISGSITKNIAFTPDK--ILFLPQRVLLTDGSLKQQVIYPYEVQAQQDYTSTGEEDDTWIIQLLDEVGLSSLCERIGGVNKPLDGNWEDMLSPGEMQRLAFARLFYHHPVIAMLDEATSALDVRTEQDLYRKCKQLGMTLISIGHRESLIPYHDINLKMLGNGKWELSTYQHDK 600          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Nematostella
Match: EDO29975 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T239])

HSP 1 Score: 179.489 bits (454), Expect = 4.002e-48
Identity = 144/532 (27.07%), Postives = 256/532 (48.12%), Query Frame = 2
Query:  506 INSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCR--IKNVDQSLTEDISVFSSSLAHLYSQL-TKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVL-MKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPATNYIELIKVPIVTPNGD-VVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLW-PIYGG---KLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKD-LQEILDIVQLEPIITREGGLD--VEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNL 2065
            I + ++F+     + +R  +  + + +YFK  ++Y +  +D    I N DQ +T+D       L  ++S+L   PF      S+  Y+ +   G    +  +I  GV +     ++LI       V    +  G  RF H +I  NSE +AF     +E      K Y  ++K    ++L     + +  F    + +      +S+ + T       G +    P    SE T+I  ++  L+G       ++I     +T+++GY  R+ EL+       +S ++   N  +Y  +    KL + +    + +LI V    P  +  +V +L L   +G ++LITG  GCGK+SL R+  GLW P+ G     +   P+  ++ + Q   L  G+L++Q+++P     ++ +   D   + ++L  V L  +  R GG+D  V+  W ++ S GE QR+  ARLFYH+P  A++DE TSA+ I  E  +Y   +  G+TL++V HR +L +FH++ LK  G+G W LS++
Sbjct:   91 IRTAVQFVANTSFVQYRAYMCRFLHSIYFKVDSHYDILILDPIKIIDNPDQRITQDTEKMMQMLKKIFSKLLIVPFT----ASYYAYQCSMVTG---YLAPLIMLGVFMVWALGIKLIMGPIINTVYRVEQTTGNFRFKHMQIRVNSEALAFNGARNLEEKKTNEKLYDMVVKCQREVNLNIFLNIAVNIF--NNISAPLCYIFISVTVFT-------GKYDYLSPSELGSEITKIAFVSTYLMG----CFTQLIDLSDTLTDMAGYIHRIGELIETL----ESCHKHKQNR-DYVNRLRNDKLREGLHPGVFFKLINVSYSIPGTEEPLVADLDLVFARGQNVLITGMAGCGKTSLLRVIRGLWEPLSGDVVRNIDFEPEKVLF-LSQHALLTNGSLKEQVVFP-----LEAEDYLDHTRIMDLLSEVGLASVCRRVGGIDSLVDGSWEDMLSHGEIQRLAFARLFYHQPDLAMMDEATSALDIATEKALYGMCVDKGITLISVAHRDTLDEFHDVHLKLLGDGKWTLSDI 591          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Medaka
Match: abcd2 (ATP-binding cassette sub-family D member 2 [Source:NCBI gene;Acc:101173669])

HSP 1 Score: 665.996 bits (1717), Expect = 0.000e+0
Identity = 340/619 (54.93%), Postives = 449/619 (72.54%), Query Frame = 2
Query:  266 VNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT------------------NNAIEYQGQSNVAKLDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            +N+ FF ++  L KI+FP+ +SKE  LL +H+  L+ RTFLSIYVA LDGKIV++IV+++  +F++QL+K+LLIA+PATF+NS IRFLE +L++ FRT+LV++ Y+ YF  QTYY+V N+D R+ N DQSLTED+ +FS S+AHLYS LTKP LD+ L S++L + AR RGAS   P ++A  VV  T   LR  SPKFG LVAEEA  KG+LR+VHSRII N+EEIAFY GH+VE   L K Y+ L  Q N I  ++LWY+MIEQFLMKYVWS  G+ MV++PI+TATG   D   VD      VSERT+ FT ARNLL + A A+ER+++SYKE+TEL+GYT+RVH +  VF D+ + +Y+ +                  +  +E +G+  V  +D  +   N      VPI+TP+GDVVV  L+L++ +G H+LITGPNGCGKSSLFRI  GLWP+YGG+L  P    M++IPQ+PY+ +G+LRDQ+IYPD    M  +G+ DKDL+ ILDIV L  I+TREGG D E DW +V SGGEKQR+GMAR+FYH+P++ALLDECTSAVSIDVE  I++ A   G++LL++THRPSLWK+H  LL+FDG GGW    L+
Sbjct:   79 LNAEFFHQILELGKILFPRLVSKELCLLSLHSVALISRTFLSIYVASLDGKIVKTIVEKEPQRFILQLVKWLLIAIPATFVNSAIRFLECKLALAFRTRLVDHAYRTYFTDQTYYKVSNMDGRLANADQSLTEDVMMFSQSVAHLYSNLTKPILDVVLTSYTLIQTARTRGASPTGPTLLAGAVVCVTAMVLRACSPKFGKLVAEEAHRKGFLRYVHSRIIANAEEIAFYRGHKVEMCQLQKCYKALADQMNLILSKRLWYIMIEQFLMKYVWSGCGLVMVAVPIITATGF-ADSEKVDGQTQVMVSERTEAFTTARNLLVSGADAIERIMSSYKEITELAGYTARVHNMFVVFEDVQKGIYKRSSLSDAAGTEKKNRPEMHIDGPLEIKGE--VIDVDKGIVCEN------VPIITPSGDVVVSCLNLKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYGGRLHKPSPQHMFYIPQRPYMSMGSLRDQVIYPDTAEDMSARGLGDKDLEAILDIVNLNHIVTREGGWDAELDWKDVLSGGEKQRMGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDTGISLLSITHRPSLWKYHTHLLQFDGVGGWRFEQLD 688          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Medaka
Match: abcd1 (ATP-binding cassette sub-family D member 1-like [Source:NCBI gene;Acc:101166202])

HSP 1 Score: 645.195 bits (1663), Expect = 0.000e+0
Identity = 328/597 (54.94%), Postives = 428/597 (71.69%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATG-RRNDGSFVDD-----DPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT---------NNAIEYQGQSNVAK----LDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            E  LL +H+  LM RTFLSIYVA LDG IV+ IVQ+D   F++QL K+LL+A+PATFINS IRFLE +LS+ FR++LV + Y++YF +QTYYRV N+D R+ N DQSLTEDI +FSSS+AHLYS LTKP LD+ +  ++L   A  +GA+   P  IA  VV+ T + LR  SP FG LVAEEAK KG LR++HSRII NSEEIAFY GH+VE   L ++Y+ L  Q ++I L++LWY+M+EQFLMKYVWS++G+ MV++PI+TATG   +D   V         +  VSERTQ FT ARNLL  +A AVER+++SYKEVTEL+GYTSRV E+L VF D+S+ +YR +             E Q +  V          +     I    +PI+TP+GDVVV  L++++ +G  +LITGPNGCGKSSLFRI  GLWP+YGG L  P    M++IPQ+PY+  GTLRDQ+IYPD++  M  KG+TD  L++IL  V L  I+ REGG +   DW ++ SGGEKQR+GMAR+FYH+P++ALLDECTSAVSIDVE NI++ A   G++LL++THRPSLWK+H+ LL+FDGEGGW    L+
Sbjct:  105 ECGLLALHSLTLMSRTFLSIYVASLDGVIVKCIVQKDPQAFVLQLSKWLLVAVPATFINSAIRFLEGQLSLRFRSRLVNHAYQVYFANQTYYRVSNMDGRLSNPDQSLTEDIVMFSSSIAHLYSNLTKPILDVVVTCYTLLSTAHAKGANTSWPAAIAGLVVVLTAKVLRSCSPHFGKLVAEEAKRKGDLRYMHSRIIANSEEIAFYGGHKVEMAQLQQSYRSLSTQIHQILLKRLWYIMLEQFLMKYVWSASGLVMVAVPIITATGYSESDSEEVKKAAMVMKEEELVSERTQAFTTARNLLNAAADAVERIMSSYKEVTELAGYTSRVSEMLDVFEDVSRGIYRRSAYREEESSGTGGDEVQPRQRVCGPLEIKGQVISVEKGIRCQNLPIITPSGDVVVSSLNIQVEEGMDVLITGPNGCGKSSLFRILSGLWPVYGGVLYRPEPQHMFYIPQRPYMSEGTLRDQVIYPDSVEDMLQKGVTDSALEQILKTVHLLYILDREGGWESISDWKDILSGGEKQRMGMARMFYHRPRYALLDECTSAVSIDVEGNIFQAAKDAGISLLSITHRPSLWKYHSHLLQFDGEGGWKFEPLD 701          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Medaka
Match: abcd1 (ATP-binding cassette sub-family D member 1-like [Source:NCBI gene;Acc:101166202])

HSP 1 Score: 645.195 bits (1663), Expect = 0.000e+0
Identity = 328/597 (54.94%), Postives = 428/597 (71.69%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATG-RRNDGSFVDD-----DPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT---------NNAIEYQGQSNVAK----LDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            E  LL +H+  LM RTFLSIYVA LDG IV+ IVQ+D   F++QL K+LL+A+PATFINS IRFLE +LS+ FR++LV + Y++YF +QTYYRV N+D R+ N DQSLTEDI +FSSS+AHLYS LTKP LD+ +  ++L   A  +GA+   P  IA  VV+ T + LR  SP FG LVAEEAK KG LR++HSRII NSEEIAFY GH+VE   L ++Y+ L  Q ++I L++LWY+M+EQFLMKYVWS++G+ MV++PI+TATG   +D   V         +  VSERTQ FT ARNLL  +A AVER+++SYKEVTEL+GYTSRV E+L VF D+S+ +YR +             E Q +  V          +     I    +PI+TP+GDVVV  L++++ +G  +LITGPNGCGKSSLFRI  GLWP+YGG L  P    M++IPQ+PY+  GTLRDQ+IYPD++  M  KG+TD  L++IL  V L  I+ REGG +   DW ++ SGGEKQR+GMAR+FYH+P++ALLDECTSAVSIDVE NI++ A   G++LL++THRPSLWK+H+ LL+FDGEGGW    L+
Sbjct:  105 ECGLLALHSLTLMSRTFLSIYVASLDGVIVKCIVQKDPQAFVLQLSKWLLVAVPATFINSAIRFLEGQLSLRFRSRLVNHAYQVYFANQTYYRVSNMDGRLSNPDQSLTEDIVMFSSSIAHLYSNLTKPILDVVVTCYTLLSTAHAKGANTSWPAAIAGLVVVLTAKVLRSCSPHFGKLVAEEAKRKGDLRYMHSRIIANSEEIAFYGGHKVEMAQLQQSYRSLSTQIHQILLKRLWYIMLEQFLMKYVWSASGLVMVAVPIITATGYSESDSEEVKKAAMVMKEEELVSERTQAFTTARNLLNAAADAVERIMSSYKEVTELAGYTSRVSEMLDVFEDVSRGIYRRSAYREEESSGTGGDEVQPRQRVCGPLEIKGQVISVEKGIRCQNLPIITPSGDVVVSSLNIQVEEGMDVLITGPNGCGKSSLFRILSGLWPVYGGVLYRPEPQHMFYIPQRPYMSEGTLRDQVIYPDSVEDMLQKGVTDSALEQILKTVHLLYILDREGGWESISDWKDILSGGEKQRMGMARMFYHRPRYALLDECTSAVSIDVEGNIFQAAKDAGISLLSITHRPSLWKYHSHLLQFDGEGGWKFEPLD 701          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Medaka
Match: abcd1 (ATP-binding cassette sub-family D member 1-like [Source:NCBI gene;Acc:101166202])

HSP 1 Score: 645.195 bits (1663), Expect = 0.000e+0
Identity = 328/597 (54.94%), Postives = 428/597 (71.69%), Query Frame = 2
Query:  335 ESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATG-RRNDGSFVDD-----DPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVT---------NNAIEYQGQSNVAK----LDDAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLE 2068
            E  LL +H+  LM RTFLSIYVA LDG IV+ IVQ+D   F++QL K+LL+A+PATFINS IRFLE +LS+ FR++LV + Y++YF +QTYYRV N+D R+ N DQSLTEDI +FSSS+AHLYS LTKP LD+ +  ++L   A  +GA+   P  IA  VV+ T + LR  SP FG LVAEEAK KG LR++HSRII NSEEIAFY GH+VE   L ++Y+ L  Q ++I L++LWY+M+EQFLMKYVWS++G+ MV++PI+TATG   +D   V         +  VSERTQ FT ARNLL  +A AVER+++SYKEVTEL+GYTSRV E+L VF D+S+ +YR +             E Q +  V          +     I    +PI+TP+GDVVV  L++++ +G  +LITGPNGCGKSSLFRI  GLWP+YGG L  P    M++IPQ+PY+  GTLRDQ+IYPD++  M  KG+TD  L++IL  V L  I+ REGG +   DW ++ SGGEKQR+GMAR+FYH+P++ALLDECTSAVSIDVE NI++ A   G++LL++THRPSLWK+H+ LL+FDGEGGW    L+
Sbjct:  105 ECGLLALHSLTLMSRTFLSIYVASLDGVIVKCIVQKDPQAFVLQLSKWLLVAVPATFINSAIRFLEGQLSLRFRSRLVNHAYQVYFANQTYYRVSNMDGRLSNPDQSLTEDIVMFSSSIAHLYSNLTKPILDVVVTCYTLLSTAHAKGANTSWPAAIAGLVVVLTAKVLRSCSPHFGKLVAEEAKRKGDLRYMHSRIIANSEEIAFYGGHKVEMAQLQQSYRSLSTQIHQILLKRLWYIMLEQFLMKYVWSASGLVMVAVPIITATGYSESDSEEVKKAAMVMKEEELVSERTQAFTTARNLLNAAADAVERIMSSYKEVTELAGYTSRVSEMLDVFEDVSRGIYRRSAYREEESSGTGGDEVQPRQRVCGPLEIKGQVISVEKGIRCQNLPIITPSGDVVVSSLNIQVEEGMDVLITGPNGCGKSSLFRILSGLWPVYGGVLYRPEPQHMFYIPQRPYMSEGTLRDQVIYPDSVEDMLQKGVTDSALEQILKTVHLLYILDREGGWESISDWKDILSGGEKQRMGMARMFYHRPRYALLDECTSAVSIDVEGNIFQAAKDAGISLLSITHRPSLWKYHSHLLQFDGEGGWKFEPLD 701          
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Medaka
Match: abcd3a (ATP binding cassette subfamily D member 3 [Source:NCBI gene;Acc:101162638])

HSP 1 Score: 395.201 bits (1014), Expect = 2.669e-127
Identity = 218/626 (34.82%), Postives = 359/626 (57.35%), Query Frame = 2
Query:  227 VNEMKTLENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPA-------TNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNLEKDEIK 2083
            +N  K  + + + V+  FF R+  +L+I+ P     E+  L +    L+ RT+  +++      I  +I+ R    F   L  F+        +N+ ++     L + FR +L +  Y  Y +  TYY++ N+D RI N DQ LT+D+  F +S+  LYS L+KP LD+ L  F L      +G +I +  ++ +G+ ++     RL  P  G +   E +++G  R+V+SR+I NSEEIAFY+G+  E   +   +++L+   +     +     ++  + KY+ +  G  +VS P L  +  R+  S          S+  + +  +  +L   + A+ R++ + +E+T LSG+T+R+ EL+ V  +L+   Y  T   +  Q +++  +    VP         + I+    P++TPNGD+++ +L+ ++  G+++L+ GPNGCGKSSLFR+   LWP++GG+LT P +  ++++PQ+PY+ LGTLRDQ+IYPD   + + KG++D+ L++ LD VQL  I+ REG  D  +DW++V SGGEKQR+ MARLFYHKPQFA+LDECTSAVS+DVE  IY     +G+TL TV+HR SLWK H   L  DG G +    +  + ++
Sbjct:   46 LNTEKDGKRDKAAVDKTFFLRVLKILRIMVPGVFCMETTYLILIASMLVTRTYCDVWMIQNGTMIESAIIGRSTKDFKNCLFSFIKFMPAIALVNNLLKLGLNELKLKFRERLTKKLYDQYLQGFTYYKMGNLDNRIANADQLLTQDVEKFCNSVVDLYSNLSKPLLDIGLYIFKLTSAIGAQGPTIMMSYLLISGLFLT-----RLRRP-IGKMTVTEQRYEGEYRYVNSRLITNSEEIAFYNGNTREKQTIYSTFKKLVDHLHSFIFFRFSMGFVDSIIAKYIATVVGYLVVSRPFLNLSHPRHLQS--------SHSDLLEDYYQSGRMLLRMSQALGRIVLAGREMTRLSGFTARITELMMVLKELNAGKYERT---MVSQQETDTTENRPLVPGRGQIIHRDHIIQFEHTPLMTPNGDMLIKDLNFKVTSGNNVLVCGPNGCGKSSLFRVLGELWPLFGGELTKPERGKLFYVPQRPYMTLGTLRDQVIYPDTCEEQRRKGISDQVLKQYLDNVQLGHILDREGSWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDFIYSHCKTVGITLFTVSHRKSLWKHHKFYLHMDGRGNYEFKPITDETVE 654          
BLAST of ATP-binding cassette sub-family D member 2 vs. Planmine SMEST
Match: SMESG000029346.1 (SMESG000029346.1)

HSP 1 Score: 493.812 bits (1270), Expect = 6.227e-171
Identity = 294/304 (96.71%), Postives = 297/304 (97.70%), Query Frame = 2
Query:   89 MSVLSKYSKLIFLGSGAVSALILAYXXXXXXXXXXXXXXIDEFLSNVNEMKTLENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQ 1000
            MSVLSKYSKLIFLGSGAVSALILAYSLSSKSKSKKPGKSIDEFLSNVNEMKTLENEGSKVNSLFFQRLKILLKIIFPKFISKESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHKFLIQLLKFLLIALPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFG LVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEV   + +  Y+
Sbjct:    1 MSVLSKYSKLIFLGSGAVSALILAYSLSSKSKSKKPGKSIDEFLSNVNEMKTLENEGSKVNSLFFQRLKILLKIIFPKFISKESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHKFLIQLLKFLLIALPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGDLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVIFMITISLYK 304          
BLAST of ATP-binding cassette sub-family D member 2 vs. Planmine SMEST
Match: SMESG000029325.1 (SMESG000029325.1)

HSP 1 Score: 493.812 bits (1270), Expect = 6.227e-171
Identity = 294/304 (96.71%), Postives = 297/304 (97.70%), Query Frame = 2
Query:   89 MSVLSKYSKLIFLGSGAVSALILAYXXXXXXXXXXXXXXIDEFLSNVNEMKTLENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQ 1000
            MSVLSKYSKLIFLGSGAVSALILAYSLSSKSKSKKPGKSIDEFLSNVNEMKTLENEGSKVNSLFFQRLKILLKIIFPKFISKESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHKFLIQLLKFLLIALPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFG LVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEV   + +  Y+
Sbjct:    1 MSVLSKYSKLIFLGSGAVSALILAYSLSSKSKSKKPGKSIDEFLSNVNEMKTLENEGSKVNSLFFQRLKILLKIIFPKFISKESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHKFLIQLLKFLLIALPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGDLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVIFMITISLYK 304          
BLAST of ATP-binding cassette sub-family D member 2 vs. Planmine SMEST
Match: SMESG000031072.1 (SMESG000031072.1)

HSP 1 Score: 419.853 bits (1078), Expect = 5.286e-137
Identity = 248/624 (39.74%), Postives = 370/624 (59.29%), Query Frame = 2
Query:  230 NEMKTLENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNA-----IEYQGQSNVAKLD-DAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNL-EKDEI 2080
            N++K  + + + +N  F + L   +KI+ P+  S E++L+ +    ++ RT   ++V     KI   I+ R    F   L KF++ A     IN+ +RF  +RL + FR+KL  YFYK Y ++ T+Y++ N D RIKNVDQ LT+DI  F +SL  LYS ++KP LD+ +  + L      +G    +  +  +GV+++  +F + ++     +   E + +G  RF++SR+I NSEEIAFY G++ E + +   Y++L      +   + +  +I+  L KY+ ++ G F +S  I  ATG+ N         D   SE+   +     ++ N A AV R++ S +++  L+G+T R+ +L     DL   +   T+N      +++  +S   K   + V   N I+   VPI+TPNGDV++ +L+  +  G ++LI GPNGCGKSSLFRIF GLWP YGGK+T P    +++IPQKPY+ +G LRDQIIYPD+L  MK K   D  L  I+  VQLE IITREGG D  +DW  V SGGEKQR+ MARLFYHKPQFA+LDECTSAVS+DVE  +Y    ++G+TL TV+HR SLWK H   L  DG+G ++   + E+ EI
Sbjct:   50 NKIKPNDTKRAGINKQFLKSLLNFIKILVPRAFSHETWLVALIAISIVGRTMCDVWVVNFTTKIESLIITRQKTAFYRDLRKFIIAAPSIALINNLLRFGIERLKLQFRSKLSSYFYKKYMRNYTFYQLANFDNRIKNVDQLLTDDIEKFCNSLVDLYSNISKPILDILIYVYKLCSALGIKGPGYLLFYLFFSGVLLT--KFRKPLTK----MTIMEQQFEGEFRFINSRLIANSEEIAFYQGNKKEKDTITIIYEKLKDHLENLIEFRFFMGIIDNVLAKYLATTVGFFSIS-RIFFATGKSNLS-------DMSQSEQMHYYYSTGRMMVNMAQAVGRVVLSGRQLASLAGFTVRIQQL----DDLLNEINSKTSNKNVVLDVKHNKESEKYKQTINVVYENNLIKFEDVPIITPNGDVLIEKLNFEVKSGCNVLICGPNGCGKSSLFRIFSGLWPQYGGKITKPINFKLFYIPQKPYMTIGNLRDQIIYPDSLDLMKMKATEDHQLYAIMKKVQLEYIITREGGWDSLRDWSEVLSGGEKQRVAMARLFYHKPQFAILDECTSAVSVDVEGTLYSYCREIGITLFTVSHRKSLWKHHEYYLYMDGKGNYDFQPISEESEI 655          
BLAST of ATP-binding cassette sub-family D member 2 vs. Planmine SMEST
Match: SMESG000031072.1 (SMESG000031072.1)

HSP 1 Score: 419.468 bits (1077), Expect = 8.953e-137
Identity = 248/624 (39.74%), Postives = 370/624 (59.29%), Query Frame = 2
Query:  230 NEMKTLENEGSKVNSLFFQRXXXXXXXXXXXXXXXESFLLCVHTFCLMIRTFLSIYVAGLDGKIVRSIVQRDVHXXXXXXXXXXXXXXPATFINSFIRFLEKRLSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSSLAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEFLRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLMKAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGRRNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELSGYTSRVHELLTVFTDLSQSVYRVTNNA-----IEYQGQSNVAKLD-DAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNL-EKDEI 2080
            N++K  + + + +N  F + L   +KI+ P+  S E++L+ +    ++ RT   ++V     KI   I+ R    F   L KF++ A     IN+ +RF  +RL + FR+KL  YFYK Y ++ T+Y++ N D RIKNVDQ LT+DI  F +SL  LYS ++KP LD+ +  + L      +G    +  +  +GV+++  +F + ++     +   E + +G  RF++SR+I NSEEIAFY G++ E + +   Y++L      +   + +  +I+  L KY+ ++ G F +S  I  ATG+ N         D   SE+   +     ++ N A AV R++ S +++  L+G+T R+ +L     DL   +   T+N      +++  +S   K   + V   N I+   VPI+TPNGDV++ +L+  +  G ++LI GPNGCGKSSLFRIF GLWP YGGK+T P    +++IPQKPY+ +G LRDQIIYPD+L  MK K   D  L  I+  VQLE IITREGG D  +DW  V SGGEKQR+ MARLFYHKPQFA+LDECTSAVS+DVE  +Y    ++G+TL TV+HR SLWK H   L  DG+G ++   + E+ EI
Sbjct:   53 NKIKPNDTKRAGINKQFLKSLLNFIKILVPRAFSHETWLVALIAISIVGRTMCDVWVVNFTTKIESLIITRQKTAFYRDLRKFIIAAPSIALINNLLRFGIERLKLQFRSKLSSYFYKKYMRNYTFYQLANFDNRIKNVDQLLTDDIEKFCNSLVDLYSNISKPILDILIYVYKLCSALGIKGPGYLLFYLFFSGVLLT--KFRKPLTK----MTIMEQQFEGEFRFINSRLIANSEEIAFYQGNKKEKDTITIIYEKLKDHLENLIEFRFFMGIIDNVLAKYLATTVGFFSIS-RIFFATGKSNLS-------DMSQSEQMHYYYSTGRMMVNMAQAVGRVVLSGRQLASLAGFTVRIQQL----DDLLNEINSKTSNKNVVLDVKHNKESEKYKQTINVVYENNLIKFEDVPIITPNGDVLIEKLNFEVKSGCNVLICGPNGCGKSSLFRIFSGLWPQYGGKITKPINFKLFYIPQKPYMTIGNLRDQIIYPDSLDLMKMKATEDHQLYAIMKKVQLEYIITREGGWDSLRDWSEVLSGGEKQRVAMARLFYHKPQFAILDECTSAVSVDVEGTLYSYCREIGITLFTVSHRKSLWKHHEYYLYMDGKGNYDFQPISEESEI 658          
BLAST of ATP-binding cassette sub-family D member 2 vs. Planmine SMEST
Match: SMESG000031072.1 (SMESG000031072.1)

HSP 1 Score: 272.707 bits (696), Expect = 5.863e-86
Identity = 129/225 (57.33%), Postives = 161/225 (71.56%), Query Frame = 2
Query: 1409 DAVPATNYIELIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWPIYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKDLQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQFALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDGEGGWNLSNL-EKDEI 2080
            + V   N I+   VPI+TPNGDV++ +L+  +  G ++LI GPNGCGKSSLFRIF GLWP YGGK+T P    +++IPQKPY+ +G LRDQIIYPD+L  MK K   D  L  I+  VQLE IITREGG D  +DW  V SGGEKQR+ MARLFYHKPQFA+LDECTSAVS+DVE  +Y    ++G+TL TV+HR SLWK H   L  DG+G ++   + E+ EI
Sbjct:   26 NVVYENNLIKFEDVPIITPNGDVLIEKLNFEVKSGCNVLICGPNGCGKSSLFRIFSGLWPQYGGKITKPINFKLFYIPQKPYMTIGNLRDQIIYPDSLDLMKMKATEDHQLYAIMKKVQLEYIITREGGWDSLRDWSEVLSGGEKQRVAMARLFYHKPQFAILDECTSAVSVDVEGTLYSYCREIGITLFTVSHRKSLWKHHEYYLYMDGKGNYDFQPISEESEI 250          
The following BLAST results are available for this feature:
BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ABCD10.000e+053.49ATP binding cassette subfamily D member 1 [Source:... [more]
ABCD20.000e+055.22ATP binding cassette subfamily D member 2 [Source:... [more]
ABCD32.117e-13938.91ATP binding cassette subfamily D member 3 [Source:... [more]
ABCD38.248e-13938.78ATP binding cassette subfamily D member 3 [Source:... [more]
ABCD14.657e-6757.95ATP binding cassette subfamily D member 1 [Source:... [more]
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BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pmp-40.000e+055.48Peroxisomal Membrane Protein related [Source:UniP... [more]
pmp-27.066e-13138.81Peroxisomal Membrane Protein related [Source:UniP... [more]
pmp-17.930e-13138.66Peroxisomal Membrane Protein related [Source:UniP... [more]
pmp-33.840e-4426.87Peroxisomal Membrane Protein related [Source:UniP... [more]
pmp-35.597e-4426.87Peroxisomal Membrane Protein related [Source:UniP... [more]
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BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ABCD0.000e+053.68gene:FBgn0039890 transcript:FBtr0089146[more]
ABCD0.000e+053.68gene:FBgn0039890 transcript:FBtr0089150[more]
ABCD0.000e+053.68gene:FBgn0039890 transcript:FBtr0089148[more]
ABCD0.000e+053.68gene:FBgn0039890 transcript:FBtr0089147[more]
ABCD0.000e+053.68gene:FBgn0039890 transcript:FBtr0308247[more]
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BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abcd10.000e+054.03ATP-binding cassette, sub-family D (ALD), member 1... [more]
abcd10.000e+052.60ATP-binding cassette, sub-family D (ALD), member 1... [more]
abcd3a8.865e-13537.58ATP-binding cassette, sub-family D (ALD), member 3... [more]
abcd3a1.977e-13437.58ATP-binding cassette, sub-family D (ALD), member 3... [more]
abcd3a1.977e-13437.58ATP-binding cassette, sub-family D (ALD), member 3... [more]
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BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
scrib0.000e+055.75scribbled planar cell polarity protein [Source:Xen... [more]
scrib0.000e+055.75scribbled planar cell polarity protein [Source:Xen... [more]
scrib0.000e+055.75scribbled planar cell polarity protein [Source:Xen... [more]
scrib0.000e+054.84scribbled planar cell polarity protein [Source:Xen... [more]
scrib0.000e+055.72scribbled planar cell polarity protein [Source:Xen... [more]
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BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Abcd20.000e+054.90ATP-binding cassette, sub-family D (ALD), member 2... [more]
Abcd10.000e+053.32ATP-binding cassette, sub-family D (ALD), member 1... [more]
Abcd32.180e-13738.52ATP-binding cassette, sub-family D (ALD), member 3... [more]
Abcd16.638e-12749.76ATP-binding cassette, sub-family D (ALD), member 1... [more]
Abcd32.138e-8648.35ATP-binding cassette, sub-family D (ALD), member 3... [more]
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BLAST of ATP-binding cassette sub-family D member 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P33897|ABCD1_HUMAN0.000e+053.49ATP-binding cassette sub-family D member 1 OS=Homo... [more]
sp|Q9UBJ2|ABCD2_HUMAN0.000e+055.22ATP-binding cassette sub-family D member 2 OS=Homo... [more]
sp|Q9QY44|ABCD2_RAT0.000e+055.07ATP-binding cassette sub-family D member 2 OS=Ratt... [more]
sp|Q61285|ABCD2_MOUSE0.000e+054.90ATP-binding cassette sub-family D member 2 OS=Mus ... [more]
sp|D3ZHR2|ABCD1_RAT0.000e+053.32ATP-binding cassette sub-family D member 1 OS=Ratt... [more]
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BLAST of ATP-binding cassette sub-family D member 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A210PS410.000e+059.35ATP-binding cassette sub-family D member 2 OS=Mizu... [more]
A0A0L8HEF70.000e+059.60Uncharacterized protein OS=Octopus bimaculoides OX... [more]
A0A2C9JCV40.000e+059.62Uncharacterized protein OS=Biomphalaria glabrata O... [more]
A0A2T7NTT50.000e+058.28Uncharacterized protein OS=Pomacea canaliculata OX... [more]
A0A1I8GFG20.000e+059.41ABC transporter domain-containing protein OS=Macro... [more]
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BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abcd20.000e+054.07ATP-binding cassette sub-family D member 2 [Source... [more]
abcd10.000e+053.07ATP-binding cassette sub-family D member 1 [Source... [more]
abcd3a1.089e-13236.94ATP binding cassette subfamily D member 3 [Source:... [more]
abcd3a1.524e-13137.10ATP binding cassette subfamily D member 3 [Source:... [more]
abcd44.854e-6130.11ATP-binding cassette, sub-family D (ALD), member 4... [more]
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BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abcd13.158e-8460.20ATP-binding cassette, sub-family D (ALD), member 1... [more]
abcd43.827e-6931.17ATP-binding cassette, sub-family D (ALD), member 4... [more]
abcb6b5.828e-1228.02ATP-binding cassette, sub-family B (MDR/TAP), memb... [more]
ABCB17.394e-1225.37ATP binding cassette subfamily B member 1 [Source:... [more]
ENSPMAT00000007076.12.285e-1127.03pep scaffold:Pmarinus_7.0:GL480539:10051:22495:1 g... [more]
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BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
PXA13.187e-9232.92Subunit of heterodimeric peroxisomal ABC transport... [more]
PXA21.698e-9132.69Subunit of heterodimeric peroxisomal ABC transport... [more]
STE62.028e-1229.26Plasma membrane ATP-binding cassette (ABC) transpo... [more]
MDL12.406e-1225.89Mitochondrial inner membrane half-type ABC transpo... [more]
MDL21.286e-1125.72Mitochondrial inner membrane half-type ABC transpo... [more]
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BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO371380.000e+054.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO337052.663e-12837.21Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO290282.640e-6165.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO395383.188e-5027.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO299754.002e-4827.07Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of ATP-binding cassette sub-family D member 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abcd20.000e+054.93ATP-binding cassette sub-family D member 2 [Source... [more]
abcd10.000e+054.94ATP-binding cassette sub-family D member 1-like [S... [more]
abcd10.000e+054.94ATP-binding cassette sub-family D member 1-like [S... [more]
abcd10.000e+054.94ATP-binding cassette sub-family D member 1-like [S... [more]
abcd3a2.669e-12734.82ATP binding cassette subfamily D member 3 [Source:... [more]
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BLAST of ATP-binding cassette sub-family D member 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000029346.16.227e-17196.71SMESG000029346.1[more]
SMESG000029325.16.227e-17196.71SMESG000029325.1[more]
SMESG000031072.15.286e-13739.74SMESG000031072.1[more]
SMESG000031072.18.953e-13739.74SMESG000031072.1[more]
SMESG000031072.15.863e-8657.33SMESG000031072.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002568 ID=SMED30002568|Name=ATP-binding cassette sub-family D member 2|organism=Schmidtea mediterranea sexual|type=transcript|length=2297bp
TGAAATTTTAAAAATTGAAAAAATATTCGGAATATATTATTCCTACTTTT
TAAAAAATACTTCCAGGAAGGATATTTTAAATTTATAAATGTCTGTTTTA
TCGAAATATTCCAAGCTTATCTTTCTTGGAAGTGGAGCTGTTAGTGCTTT
AATTTTGGCATATTCCTTGTCAAGTAAAAGTAAAAGTAAAAAACCTGGAA
AATCGATAGATGAATTCTTGTCGAATGTTAATGAAATGAAAACTTTAGAA
AATGAAGGTTCTAAAGTTAATTCATTATTTTTTCAGCGGCTTAAAATATT
ATTGAAAATAATATTTCCCAAATTCATTTCAAAAGAATCATTTCTGTTAT
GTGTTCATACATTCTGTTTAATGATAAGGACATTTTTGAGTATTTATGTA
GCAGGTTTAGATGGTAAAATAGTCAGATCAATAGTTCAAAGAGATGTTCA
TAAATTTTTAATTCAATTATTGAAATTCTTATTGATTGCACTGCCTGCTA
CATTTATTAATAGTTTTATCAGATTTCTTGAAAAAAGATTATCAATTTGT
TTCAGAACTAAATTAGTTGAATATTTTTATAAACTTTATTTTAAACATCA
AACTTATTATCGAGTGGAAAATATCGATTGTCGAATTAAAAATGTTGACC
AAAGTCTCACAGAAGATATTTCAGTATTTTCATCGTCATTGGCTCATTTA
TATTCTCAATTAACGAAACCATTTCTGGATCTCTGCTTAATGTCATTTTC
ATTATATAAGCTTGCCCGAAATCGGGGAGCTAGTATAAGAATTCCGTGTA
TTATTGCGGCCGGAGTTGTTATTTCAACTGGGGAATTTTTGCGGTTAATA
AGTCCAAAATTCGGAGTTTTGGTAGCTGAAGAAGCTAAACATAAAGGATA
TTTGCGTTTTGTTCATTCGAGAATCATTCAAAATTCCGAGGAAATCGCAT
TTTACAGTGGTCATGAGGTGGAATCTAATGTTCTAATGAAAGCGTATCAA
GAATTGATTAAACAAACAAATAGAATTTCTCTACAAAAATTGTGGTATGT
GATGATTGAACAATTTCTAATGAAATACGTCTGGAGTTCAACGGGCATGT
TTATGGTCTCTATTCCTATTTTAACTGCAACTGGCAGGAGGAATGATGGA
TCATTTGTTGATGATGATCCCGATGGTGGAGTTTCAGAACGAACACAGAT
TTTTACCATGGCAAGGAATTTATTGGGTAATTCTGCATCAGCTGTCGAGC
GAATGATTACTTCATACAAGGAAGTAACGGAATTATCAGGCTATACATCT
CGAGTTCATGAATTGTTGACTGTTTTCACTGACTTATCTCAATCAGTTTA
CCGTGTGACAAACAATGCTATCGAATATCAAGGACAATCAAATGTAGCTA
AATTAGATGACGCAGTACCGGCAACGAATTACATTGAATTAATAAAAGTT
CCTATTGTAACACCTAATGGGGATGTTGTAGTACCAGAATTATCTTTAAG
GATTAATAAAGGAGATCACATTTTGATTACTGGTCCAAATGGGTGCGGAA
AAAGTTCACTTTTTAGAATTTTTCACGGACTCTGGCCTATTTATGGTGGT
AAACTGACAACACCACCAAAAAATACAATGTATCATATTCCACAAAAGCC
CTATCTATTTCTCGGAACTTTGAGAGATCAAATTATTTATCCTGATAATT
TGATTCAAATGAAAAACAAAGGCATGACAGATAAAGATCTTCAGGAGATT
TTAGATATTGTTCAATTAGAACCAATTATTACACGCGAAGGAGGATTAGA
TGTTGAAAAGGATTGGATTAATGTATTTTCTGGTGGAGAAAAACAAAGGA
TAGGAATGGCGAGATTATTTTATCACAAACCTCAGTTTGCACTTTTGGAT
GAATGCACGAGTGCAGTTTCCATTGATGTTGAATCGAATATTTATGAGAC
GGCAATAAAAATGGGCATGACATTATTAACAGTAACCCATAGGCCTTCAC
TGTGGAAATTTCACAATTTACTTTTGAAATTTGACGGTGAAGGGGGCTGG
AACTTGTCGAACCTCGAAAAAGACGAAATTAAGAATGACTGAATTCTCTA
TACGAAGATTAATTATTGTTTAATTTAATTTTCATCTATTAATTTTGTAA
TTTTAATCTTTTTCTCCCAATCTTCGACATTTGAATATTTTGAAAAACTT
GAAATATTGATGGTAACTCTCAAAATCGATAAAGATACTCAAACTCCAAT
CTCCGATAATCCTTCATTTTGTTATAAAATTATTAGCCTTTAAACAA
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protein sequence of SMED30002568-orf-1

>SMED30002568-orf-1 ID=SMED30002568-orf-1|Name=SMED30002568-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=668bp
MSVLSKYSKLIFLGSGAVSALILAYSLSSKSKSKKPGKSIDEFLSNVNEM
KTLENEGSKVNSLFFQRLKILLKIIFPKFISKESFLLCVHTFCLMIRTFL
SIYVAGLDGKIVRSIVQRDVHKFLIQLLKFLLIALPATFINSFIRFLEKR
LSICFRTKLVEYFYKLYFKHQTYYRVENIDCRIKNVDQSLTEDISVFSSS
LAHLYSQLTKPFLDLCLMSFSLYKLARNRGASIRIPCIIAAGVVISTGEF
LRLISPKFGVLVAEEAKHKGYLRFVHSRIIQNSEEIAFYSGHEVESNVLM
KAYQELIKQTNRISLQKLWYVMIEQFLMKYVWSSTGMFMVSIPILTATGR
RNDGSFVDDDPDGGVSERTQIFTMARNLLGNSASAVERMITSYKEVTELS
GYTSRVHELLTVFTDLSQSVYRVTNNAIEYQGQSNVAKLDDAVPATNYIE
LIKVPIVTPNGDVVVPELSLRINKGDHILITGPNGCGKSSLFRIFHGLWP
IYGGKLTTPPKNTMYHIPQKPYLFLGTLRDQIIYPDNLIQMKNKGMTDKD
LQEILDIVQLEPIITREGGLDVEKDWINVFSGGEKQRIGMARLFYHKPQF
ALLDECTSAVSIDVESNIYETAIKMGMTLLTVTHRPSLWKFHNLLLKFDG
EGGWNLSNLEKDEIKND*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0000038very long-chain fatty acid metabolic process
GO:0055085transmembrane transport
GO:0006810transport
GO:0006635fatty acid beta-oxidation
Vocabulary: cellular component
TermDefinition
GO:0005777peroxisome
GO:0016021integral component of membrane
GO:0005778peroxisomal membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR031237ALDP
IPR036640ABC1_TM_sf
IPR003593AAA+_ATPase
IPR011527ABC1_TM_dom
IPR003439ABC_transporter-like
IPR027417P-loop_NTPase
IPR017871ABC_transporter_CS
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0042626ATPase activity, coupled to transmembrane movement of substances
GO:0016887ATPase activity
GO:0000166nucleotide binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003593AAA+ ATPase domainSMARTSM00382AAA_5coord: 474..660
e-value: 3.4E-6
score: 36.6
IPR011527ABC transporter type 1, transmembrane domainPFAMPF06472ABC_membrane_2coord: 71..345
e-value: 2.2E-93
score: 312.6
IPR011527ABC transporter type 1, transmembrane domainPROSITEPS50929ABC_TM1Fcoord: 91..328
score: 10.946
IPR003439ABC transporter-likePFAMPF00005ABC_trancoord: 467..608
e-value: 5.8E-17
score: 62.5
IPR003439ABC transporter-likePROSITEPS50893ABC_TRANSPORTER_2coord: 449..667
score: 12.652
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 418..651
e-value: 5.5E-39
score: 136.0
NoneNo IPR availablePANTHERPTHR11384ATP-BINDING CASSETTE, SUB-FAMILY D MEMBERcoord: 48..660
NoneNo IPR availableCDDcd03223ABCD_peroxisomal_ALDPcoord: 449..654
e-value: 5.00096E-77
score: 241.289
NoneNo IPR availableTMHMMTMhelixcoord: 85..107
NoneNo IPR availableTMHMMTMhelixcoord: 230..252
NoneNo IPR availableTMHMMTMhelixcoord: 122..144
NoneNo IPR availableTMHMMTMhelixcoord: 10..29
IPR031237ATP-binding cassette sub-family D member 1PANTHERPTHR11384:SF21ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1coord: 48..660
IPR017871ABC transporter, conserved sitePROSITEPS00211ABC_TRANSPORTER_1coord: 580..594
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 448..649
IPR036640ABC transporter type 1, transmembrane domain superfamilySUPERFAMILYSSF90123ABC transporter transmembrane regioncoord: 78..334