U-actitoxin-Avd3j

Overview


Name	U-actitoxin-Avd3j
Smed ID	SMED30002548
Length (bp)	180

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30002548

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
Smed sexual biotype	SMED30002548	SMESG000044382.1	Contig55339	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30002548	SMESG000044382.1	Contig55339	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30002548	SMESG000044382.1	Contig32141	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30002548	SMESG000044382.1	Contig32141	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
whole organism	SMED30002548	SMESG000044382.1	Contig32141	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016
whole organism	SMED30002548	SMESG000044382.1	Contig32141	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016

Note: Hover over icons to view figure legend

Homology

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BLAST of U-actitoxin-Avd3j vs. Ensembl Human
Match: WFIKKN2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30916])

HSP 1 Score: 60.077 bits (144), Expect = 4.069e-12
Identity = 23/41 (56.10%), Postives = 33/41 (80.49%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQN 167
            C+A  PR+ YNS+TG+C+ F+YGGC GN NNF+S + CE++
Sbjct:  302 CKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEES 342

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BLAST of U-actitoxin-Avd3j vs. Ensembl Human
Match: WFIKKN2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30916])

HSP 1 Score: 59.3066 bits (142), Expect = 8.757e-12
Identity = 23/41 (56.10%), Postives = 33/41 (80.49%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQN 167
            C+A  PR+ YNS+TG+C+ F+YGGC GN NNF+S + CE++
Sbjct:  395 CKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEES 435

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BLAST of U-actitoxin-Avd3j vs. Ensembl Human
Match: APLP2 (amyloid beta precursor like protein 2 [Source:HGNC Symbol;Acc:HGNC:598])

HSP 1 Score: 58.5362 bits (140), Expect = 1.435e-11
Identity = 21/38 (55.26%), Postives = 30/38 (78.95%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A++PR+Y++   GKC +FIYGGC GN+NNF+S   C
Sbjct:  319 CRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYC 356

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Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A++PR+Y++   GKC +FIYGGC GN+NNF+S   C
Sbjct:  319 CRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYC 356

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BLAST of U-actitoxin-Avd3j vs. Ensembl Human
Match: APLP2 (amyloid beta precursor like protein 2 [Source:HGNC Symbol;Acc:HGNC:598])

HSP 1 Score: 58.5362 bits (140), Expect = 1.449e-11
Identity = 21/38 (55.26%), Postives = 30/38 (78.95%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A++PR+Y++   GKC +FIYGGC GN+NNF+S   C
Sbjct:  319 CRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYC 356

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BLAST of U-actitoxin-Avd3j vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 53.5286 bits (127), Expect = 3.243e-10
Identity = 20/42 (47.62%), Postives = 29/42 (69.05%), Query Frame = 3

Query:   39 ALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
             +C    PR+++NS+TG+CE+F YG C GN+NNF     CE+
Sbjct: 2175 GVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCER 2216

HSP 2 Score: 49.6766 bits (117), Expect = 8.221e-9
Identity = 19/39 (48.72%), Postives = 25/39 (64.10%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C     RY+YN  + KCE+F Y GC GN NN++S + CE
Sbjct:  432 CHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACE 470

HSP 3 Score: 49.2914 bits (116), Expect = 1.010e-8
Identity = 19/42 (45.24%), Postives = 27/42 (64.29%), Query Frame = 3

Query:   36 RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            R  C     R+Y+N+   +C+ F +GGC GNQNNF+  +DCE
Sbjct:  545 RGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCE 586

HSP 4 Score: 46.595 bits (109), Expect = 8.738e-8
Identity = 23/43 (53.49%), Postives = 25/43 (58.14%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLC 173
            CQ    RYYY+  T  C  F Y GC GN NNF S +DC Q LC
Sbjct: 2742 CQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDC-QRLC 2783

HSP 5 Score: 46.595 bits (109), Expect = 9.545e-8
Identity = 18/39 (46.15%), Postives = 25/39 (64.10%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C+    R+Y+N   G C  F YGGC GN+N+F + K+CE
Sbjct: 1083 CKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECE 1121

HSP 6 Score: 41.9726 bits (97), Expect = 4.486e-6
Identity = 15/44 (34.09%), Postives = 22/44 (50.00%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLCN 176
            C  +  R+ ++     C  F YGGC GN NNF + ++C     N
Sbjct:  866 CAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCVN 909

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BLAST of U-actitoxin-Avd3j vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 53.5286 bits (127), Expect = 3.243e-10
Identity = 20/42 (47.62%), Postives = 29/42 (69.05%), Query Frame = 3

Query:   39 ALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
             +C    PR+++NS+TG+CE+F YG C GN+NNF     CE+
Sbjct: 2184 GVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCER 2225

HSP 2 Score: 49.6766 bits (117), Expect = 8.221e-9
Identity = 19/39 (48.72%), Postives = 25/39 (64.10%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C     RY+YN  + KCE+F Y GC GN NN++S + CE
Sbjct:  432 CHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACE 470

HSP 3 Score: 49.2914 bits (116), Expect = 1.030e-8
Identity = 19/42 (45.24%), Postives = 27/42 (64.29%), Query Frame = 3

Query:   36 RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            R  C     R+Y+N+   +C+ F +GGC GNQNNF+  +DCE
Sbjct:  545 RGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCE 586

HSP 4 Score: 46.595 bits (109), Expect = 8.824e-8
Identity = 23/43 (53.49%), Postives = 25/43 (58.14%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLC 173
            CQ    RYYY+  T  C  F Y GC GN NNF S +DC Q LC
Sbjct: 2751 CQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDC-QRLC 2792

HSP 5 Score: 46.595 bits (109), Expect = 9.639e-8
Identity = 18/39 (46.15%), Postives = 25/39 (64.10%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C+    R+Y+N   G C  F YGGC GN+N+F + K+CE
Sbjct: 1092 CKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECE 1130

HSP 6 Score: 41.9726 bits (97), Expect = 4.486e-6
Identity = 15/44 (34.09%), Postives = 22/44 (50.00%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLCN 176
            C  +  R+ ++     C  F YGGC GN NNF + ++C     N
Sbjct:  875 CAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCVN 918

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BLAST of U-actitoxin-Avd3j vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 53.5286 bits (127), Expect = 3.646e-10
Identity = 20/42 (47.62%), Postives = 29/42 (69.05%), Query Frame = 3

Query:   39 ALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
             +C    PR+++NS+TG+CE+F YG C GN+NNF     CE+
Sbjct: 2055 GVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCER 2096

HSP 2 Score: 49.2914 bits (116), Expect = 9.246e-9
Identity = 19/39 (48.72%), Postives = 25/39 (64.10%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C     RY+YN  + KCE+F Y GC GN NN++S + CE
Sbjct:  303 CHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACE 341

HSP 3 Score: 49.2914 bits (116), Expect = 1.136e-8
Identity = 19/42 (45.24%), Postives = 27/42 (64.29%), Query Frame = 3

Query:   36 RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            R  C     R+Y+N+   +C+ F +GGC GNQNNF+  +DCE
Sbjct:  416 RGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCE 457

HSP 4 Score: 46.595 bits (109), Expect = 9.828e-8
Identity = 23/43 (53.49%), Postives = 25/43 (58.14%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLC 173
            CQ    RYYY+  T  C  F Y GC GN NNF S +DC Q LC
Sbjct: 2622 CQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDC-QRLC 2663

HSP 5 Score: 46.2098 bits (108), Expect = 1.063e-7
Identity = 18/39 (46.15%), Postives = 25/39 (64.10%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C+    R+Y+N   G C  F YGGC GN+N+F + K+CE
Sbjct:  963 CKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECE 1001

HSP 6 Score: 41.5874 bits (96), Expect = 4.900e-6
Identity = 15/44 (34.09%), Postives = 22/44 (50.00%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLCN 176
            C  +  R+ ++     C  F YGGC GN NNF + ++C     N
Sbjct:  746 CAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCVN 789

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3e.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 52.7582 bits (125), Expect = 6.368e-10
Identity = 20/42 (47.62%), Postives = 29/42 (69.05%), Query Frame = 3

Query:   39 ALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
             +C    PR+++NS+TG+CE+F YG C GN+NNF     CE+
Sbjct: 1658 GVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCER 1699

HSP 2 Score: 48.9062 bits (115), Expect = 1.509e-8
Identity = 19/39 (48.72%), Postives = 25/39 (64.10%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C     RY+YN  + KCE+F Y GC GN NN++S + CE
Sbjct:  432 CHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACE 470

HSP 3 Score: 48.521 bits (114), Expect = 1.835e-8
Identity = 19/42 (45.24%), Postives = 27/42 (64.29%), Query Frame = 3

Query:   36 RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            R  C     R+Y+N+   +C+ F +GGC GNQNNF+  +DCE
Sbjct:  545 RGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCE 586

HSP 4 Score: 45.8246 bits (107), Expect = 1.685e-7
Identity = 23/43 (53.49%), Postives = 25/43 (58.14%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLC 173
            CQ    RYYY+  T  C  F Y GC GN NNF S +DC Q LC
Sbjct: 2225 CQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDC-QRLC 2266

HSP 5 Score: 45.8246 bits (107), Expect = 1.735e-7
Identity = 18/39 (46.15%), Postives = 25/39 (64.10%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C+    R+Y+N   G C  F YGGC GN+N+F + K+CE
Sbjct: 1092 CKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECE 1130

HSP 6 Score: 41.2022 bits (95), Expect = 7.473e-6
Identity = 15/44 (34.09%), Postives = 22/44 (50.00%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLCN 176
            C  +  R+ ++     C  F YGGC GN NNF + ++C     N
Sbjct:  875 CAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCVN 918

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3f.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 52.373 bits (124), Expect = 7.667e-10
Identity = 20/42 (47.62%), Postives = 29/42 (69.05%), Query Frame = 3

Query:   39 ALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
             +C    PR+++NS+TG+CE+F YG C GN+NNF     CE+
Sbjct: 1437 GVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCER 1478

HSP 2 Score: 48.521 bits (114), Expect = 1.799e-8
Identity = 19/39 (48.72%), Postives = 25/39 (64.10%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C     RY+YN  + KCE+F Y GC GN NN++S + CE
Sbjct:  211 CHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACE 249

HSP 3 Score: 48.1358 bits (113), Expect = 2.210e-8
Identity = 19/42 (45.24%), Postives = 27/42 (64.29%), Query Frame = 3

Query:   36 RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            R  C     R+Y+N+   +C+ F +GGC GNQNNF+  +DCE
Sbjct:  324 RGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCE 365

HSP 4 Score: 45.4394 bits (106), Expect = 1.971e-7
Identity = 23/43 (53.49%), Postives = 25/43 (58.14%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLC 173
            CQ    RYYY+  T  C  F Y GC GN NNF S +DC Q LC
Sbjct: 2004 CQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDC-QRLC 2045

HSP 5 Score: 45.4394 bits (106), Expect = 2.010e-7
Identity = 18/39 (46.15%), Postives = 25/39 (64.10%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C+    R+Y+N   G C  F YGGC GN+N+F + K+CE
Sbjct:  871 CKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECE 909

HSP 6 Score: 41.2022 bits (95), Expect = 8.242e-6
Identity = 15/44 (34.09%), Postives = 22/44 (50.00%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLCN 176
            C  +  R+ ++     C  F YGGC GN NNF + ++C     N
Sbjct:  654 CAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCVN 697

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Fly
Match: CG13748 (gene:FBgn0033355 transcript:FBtr0088656)

HSP 1 Score: 54.6842 bits (130), Expect = 1.971e-11
Identity = 22/48 (45.83%), Postives = 36/48 (75.00%), Query Frame = 3

Query:   15 MLPSKE*RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            ++P++  + +C+A+IPR+ Y+ +  KC +F +GGC GN+NNF S KDC
Sbjct:   61 LMPAR--KGVCRALIPRWRYDPEQKKCVEFKFGGCDGNENNFASYKDC 106

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0077545)

HSP 1 Score: 53.5286 bits (127), Expect = 6.835e-11
Identity = 23/40 (57.50%), Postives = 29/40 (72.50%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            C A+  RY YN  T  CE+F+YGGC GN+NNF+S + CEQ
Sbjct:   64 CFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQ 103

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0346581)

HSP 1 Score: 53.5286 bits (127), Expect = 6.835e-11
Identity = 23/40 (57.50%), Postives = 29/40 (72.50%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            C A+  RY YN  T  CE+F+YGGC GN+NNF+S + CEQ
Sbjct:   64 CFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQ 103

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Fly
Match: IM33 (gene:FBgn0031561 transcript:FBtr0077546)

HSP 1 Score: 51.6026 bits (122), Expect = 1.347e-10
Identity = 22/40 (55.00%), Postives = 28/40 (70.00%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            C A IP + Y+ +T  CEKFIYGGC GN+N F + + CEQ
Sbjct:   39 CAAFIPSFSYHPETNSCEKFIYGGCGGNENRFGTQELCEQ 78

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Fly
Match: IM33 (gene:FBgn0031561 transcript:FBtr0345610)

HSP 1 Score: 51.6026 bits (122), Expect = 1.347e-10
Identity = 22/40 (55.00%), Postives = 28/40 (70.00%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            C A IP + Y+ +T  CEKFIYGGC GN+N F + + CEQ
Sbjct:   39 CAAFIPSFSYHPETNSCEKFIYGGCGGNENRFGTQELCEQ 78

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Zebrafish
Match: tfpia (tissue factor pathway inhibitor a [Source:ZFIN;Acc:ZDB-GENE-030711-1])

HSP 1 Score: 53.5286 bits (127), Expect = 4.375e-10
Identity = 21/40 (52.50%), Postives = 32/40 (80.00%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            C+A+  R+Y++  TG+CE F YGGC+GN NNF++ +DCE+
Sbjct:   51 CKAMKDRFYFDIDTGRCEPFEYGGCQGNANNFETLQDCEE 90

HSP 2 Score: 51.9878 bits (123), Expect = 1.734e-9
Identity = 19/40 (47.50%), Postives = 32/40 (80.00%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            C+ ++PRY+++ K+ +C++F YGGC GN NNF++ K C+Q
Sbjct:  110 CRGLVPRYFFDQKSQECKQFFYGGCFGNANNFKTIKACQQ 149

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Zebrafish
Match: tfpia (tissue factor pathway inhibitor a [Source:ZFIN;Acc:ZDB-GENE-030711-1])

HSP 1 Score: 53.5286 bits (127), Expect = 4.631e-10
Identity = 21/40 (52.50%), Postives = 32/40 (80.00%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            C+A+  R+Y++  TG+CE F YGGC+GN NNF++ +DCE+
Sbjct:   50 CKAMKDRFYFDIDTGRCEPFEYGGCQGNANNFETLQDCEE 89

HSP 2 Score: 51.9878 bits (123), Expect = 1.747e-9
Identity = 19/40 (47.50%), Postives = 32/40 (80.00%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            C+ ++PRY+++ K+ +C++F YGGC GN NNF++ K C+Q
Sbjct:  109 CRGLVPRYFFDQKSQECKQFFYGGCFGNANNFKTIKACQQ 148

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Zebrafish
Match: appb (amyloid beta (A4) precursor protein b [Source:ZFIN;Acc:ZDB-GENE-020220-1])

HSP 1 Score: 53.1434 bits (126), Expect = 7.167e-10
Identity = 18/38 (47.37%), Postives = 28/38 (73.68%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C A +PR+Y+ ++ G+C  F +GGC GN+NNF+S + C
Sbjct:  315 CHAKLPRWYFVAEKGRCASFTFGGCGGNRNNFESEEYC 352

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Zebrafish
Match: aplp2 (amyloid beta (A4) precursor-like protein 2 [Source:ZFIN;Acc:ZDB-GENE-061009-28])

HSP 1 Score: 53.1434 bits (126), Expect = 7.171e-10
Identity = 19/38 (50.00%), Postives = 29/38 (76.32%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A +PR++++ +  KC +FIYGGC GN+NNF S + C
Sbjct:  324 CRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYC 361

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Zebrafish
Match: appb (amyloid beta (A4) precursor protein b [Source:ZFIN;Acc:ZDB-GENE-020220-1])

HSP 1 Score: 53.1434 bits (126), Expect = 7.825e-10
Identity = 18/38 (47.37%), Postives = 28/38 (73.68%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C A +PR+Y+ ++ G+C  F +GGC GN+NNF+S + C
Sbjct:  304 CHAKLPRWYFVAEKGRCASFTFGGCGGNRNNFESEEYC 341

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Xenopus
Match: gtf2e2 (general transcription factor IIE subunit 2 [Source:Xenbase;Acc:XB-GENE-962385])

HSP 1 Score: 56.9954 bits (136), Expect = 4.638e-11
Identity = 22/38 (57.89%), Postives = 28/38 (73.68%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A+IPR+YY+    KC +FIYGGC GN+NNF S   C
Sbjct:  310 CRAMIPRWYYDVTERKCAQFIYGGCGGNRNNFDSEDYC 347

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Xenopus
Match: gtf2e2 (general transcription factor IIE subunit 2 [Source:Xenbase;Acc:XB-GENE-962385])

HSP 1 Score: 56.9954 bits (136), Expect = 5.164e-11
Identity = 22/38 (57.89%), Postives = 28/38 (73.68%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A+IPR+YY+    KC +FIYGGC GN+NNF S   C
Sbjct:  298 CRAMIPRWYYDVTERKCAQFIYGGCGGNRNNFDSEDYC 335

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Xenopus
Match: gtf2e2 (general transcription factor IIE subunit 2 [Source:Xenbase;Acc:XB-GENE-962385])

HSP 1 Score: 56.6102 bits (135), Expect = 5.637e-11
Identity = 22/38 (57.89%), Postives = 28/38 (73.68%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A+IPR+YY+    KC +FIYGGC GN+NNF S   C
Sbjct:  288 CRAMIPRWYYDVTERKCAQFIYGGCGGNRNNFDSEDYC 325

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Xenopus
Match: gtf2e2 (general transcription factor IIE subunit 2 [Source:Xenbase;Acc:XB-GENE-962385])

HSP 1 Score: 56.6102 bits (135), Expect = 6.040e-11
Identity = 22/38 (57.89%), Postives = 28/38 (73.68%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A+IPR+YY+    KC +FIYGGC GN+NNF S   C
Sbjct:  298 CRAMIPRWYYDVTERKCAQFIYGGCGGNRNNFDSEDYC 335

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Xenopus
Match: gtf2e2 (general transcription factor IIE subunit 2 [Source:Xenbase;Acc:XB-GENE-962385])

HSP 1 Score: 56.6102 bits (135), Expect = 6.095e-11
Identity = 22/38 (57.89%), Postives = 28/38 (73.68%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A+IPR+YY+    KC +FIYGGC GN+NNF S   C
Sbjct:  264 CRAMIPRWYYDVTERKCAQFIYGGCGGNRNNFDSEDYC 301

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Mouse
Match: Spint3 (serine peptidase inhibitor, Kunitz type, 3 [Source:MGI Symbol;Acc:MGI:3651470])

HSP 1 Score: 58.151 bits (139), Expect = 6.321e-13
Identity = 25/39 (64.10%), Postives = 31/39 (79.49%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C+A+  R+YYNSKTGKCE F YGGC+GN+NNF S   C+
Sbjct:   44 CRAVFVRWYYNSKTGKCEWFRYGGCKGNENNFPSRSQCQ 82

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Mouse
Match: Wfikkn2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:MGI Symbol;Acc:MGI:2669209])

HSP 1 Score: 59.3066 bits (142), Expect = 5.724e-12
Identity = 23/41 (56.10%), Postives = 33/41 (80.49%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQN 167
            C+A +PR+ YNS+TG C+ F+YGGC GN NNF+S + CE++
Sbjct:  390 CKAYVPRWAYNSQTGLCQSFVYGGCEGNGNNFESREACEES 430

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Mouse
Match: Aplp2 (amyloid beta (A4) precursor-like protein 2 [Source:MGI Symbol;Acc:MGI:88047])

HSP 1 Score: 58.5362 bits (140), Expect = 9.379e-12
Identity = 21/38 (55.26%), Postives = 30/38 (78.95%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A++PR+Y++   GKC +FIYGGC GN+NNF+S   C
Sbjct:  319 CRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYC 356

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Mouse
Match: Aplp2 (amyloid beta (A4) precursor-like protein 2 [Source:MGI Symbol;Acc:MGI:88047])

HSP 1 Score: 57.3806 bits (137), Expect = 2.210e-11
Identity = 21/38 (55.26%), Postives = 30/38 (78.95%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A++PR+Y++   GKC +FIYGGC GN+NNF+S   C
Sbjct:  319 CRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYC 356

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Mouse
Match: Spint2 (serine protease inhibitor, Kunitz type 2 [Source:MGI Symbol;Acc:MGI:1338031])

HSP 1 Score: 54.299 bits (129), Expect = 2.149e-10
Identity = 21/38 (55.26%), Postives = 29/38 (76.32%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A IPR++YN   G C+ F+YGGC GN NN+QS ++C
Sbjct:   47 CRASIPRWWYNITDGSCQPFVYGGCEGNGNNYQSKEEC 84

HSP 2 Score: 50.447 bits (119), Expect = 5.765e-9
Identity = 20/41 (48.78%), Postives = 30/41 (73.17%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQN 167
            C+A  PR+YY+++   C  FIYGGCRGN+N++ S + C Q+
Sbjct:  142 CRAAFPRWYYDTEKNSCISFIYGGCRGNKNSYLSQEACMQH 182

[Close]

BLAST of U-actitoxin-Avd3j vs. UniProt/SwissProt
Match: sp|Q8WPI3|BOOG2_RHIMP (Boophilin-G2 OS=Rhipicephalus microplus OX=6941 GN=G2 PE=1 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 1.002e-13
Identity = 26/49 (53.06%), Postives = 40/49 (81.63%), Query Frame = 3

Query:   18 LPSKE*RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            LP+ E   +C+A+IPR+Y+N++TGKC  F YGGC GN+NNF++ +DC++
Sbjct:   23 LPADE--GICKALIPRFYFNTETGKCTMFSYGGCGGNENNFETIEDCQK 69

HSP 2 Score: 51.9878 bits (123), Expect = 3.518e-9
Identity = 19/39 (48.72%), Postives = 30/39 (76.92%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C   + R++YN ++G+CE F+YGGC GN NN++S ++CE
Sbjct:   98 CAGQLERWFYNVRSGECETFVYGGCGGNDNNYESEEECE 136

[Close]

BLAST of U-actitoxin-Avd3j vs. UniProt/SwissProt
Match: sp|P0DN09|VKT5_ANEVI (U-actitoxin-Avd3h OS=Anemonia viridis OX=51769 PE=3 SV=1)

HSP 1 Score: 62.003 bits (149), Expect = 1.221e-13
Identity = 26/40 (65.00%), Postives = 33/40 (82.50%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            C+A  PRYYYNS + +CEKFIYGGCRGN NNF + ++CE+
Sbjct:   30 CRARFPRYYYNSSSKRCEKFIYGGCRGNANNFHTLEECEK 69

[Close]

BLAST of U-actitoxin-Avd3j vs. UniProt/SwissProt
Match: sp|P0DN12|VKT8_ANEVI (U-actitoxin-Avd3k OS=Anemonia viridis OX=51769 PE=3 SV=1)

HSP 1 Score: 62.003 bits (149), Expect = 1.407e-13
Identity = 30/50 (60.00%), Postives = 37/50 (74.00%), Query Frame = 3

Query:   15 MLPSKE*RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            +LP    R  C+A  PRYYYNS + +CEKFIYGGCRGN NNF + K+CE+
Sbjct:   22 LLPMDVGR--CRARHPRYYYNSSSKRCEKFIYGGCRGNANNFITKKECEK 69

[Close]

BLAST of U-actitoxin-Avd3j vs. UniProt/SwissProt
Match: sp|Q9TWG0|VKT1_ANESU (KappaPI-actitoxin-Avd3b OS=Anemonia sulcata OX=6108 PE=1 SV=1)

HSP 1 Score: 61.2326 bits (147), Expect = 1.510e-13
Identity = 29/50 (58.00%), Postives = 37/50 (74.00%), Query Frame = 3

Query:   15 MLPSKE*RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            +LP    R  C+A  PRYYYNS + +CEKFIYGGCRGN NNF + ++CE+
Sbjct:    6 LLPMDVGR--CRASHPRYYYNSSSKRCEKFIYGGCRGNANNFHTLEECEK 53

[Close]

BLAST of U-actitoxin-Avd3j vs. UniProt/SwissProt
Match: sp|Q9TWF9|VKT2_ANESU (KappaPI-actitoxin-Avd3c OS=Anemonia sulcata OX=6108 PE=1 SV=1)

HSP 1 Score: 61.2326 bits (147), Expect = 1.578e-13
Identity = 30/50 (60.00%), Postives = 37/50 (74.00%), Query Frame = 3

Query:   15 MLPSKE*RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            +LP    R  C+A  PRYYYNS + +CEKFIYGGCRGN NNF + K+CE+
Sbjct:    6 LLPMDVGR--CRARHPRYYYNSSSRRCEKFIYGGCRGNANNFITKKECEK 53

[Close]

BLAST of U-actitoxin-Avd3j vs. TrEMBL
Match: I1ZII0 (Serine protease inhibitor-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 4.292e-18
Identity = 37/41 (90.24%), Postives = 39/41 (95.12%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQN 167
            C+A  PRYYYNSKTGKCEKFIYGGC+GNQNNFQSSKDCEQN
Sbjct:   32 CKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQN 72

[Close]

BLAST of U-actitoxin-Avd3j vs. TrEMBL
Match: A0A2P6KJJ0 (BPTI/Kunitz domain-containing protein OS=Nephila clavipes OX=2585209 GN=NCL1_38046 PE=4 SV=1)

HSP 1 Score: 65.4698 bits (158), Expect = 2.950e-12
Identity = 29/39 (74.36%), Postives = 33/39 (84.62%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C+A IPRYYYN KT KCEKFIYGGC GN NNF++ +DCE
Sbjct:   62 CKAAIPRYYYNKKTKKCEKFIYGGCNGNSNNFRTLEDCE 100

[Close]

BLAST of U-actitoxin-Avd3j vs. TrEMBL
Match: H9GB43 (Uncharacterized protein OS=Anolis carolinensis OX=28377 PE=4 SV=1)

HSP 1 Score: 65.0846 bits (157), Expect = 6.148e-12
Identity = 27/50 (54.00%), Postives = 39/50 (78.00%), Query Frame = 3

Query:   12 YMLPSKE*RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            ++LP+      C+A++PRY+YN K+ +CEKFIYGGC GN+NNF++ KDC 
Sbjct:   31 HLLPNP---GPCRAVVPRYFYNPKSNRCEKFIYGGCHGNKNNFETLKDCH 77

[Close]

BLAST of U-actitoxin-Avd3j vs. TrEMBL
Match: A0A2P6JVV9 (U-actitoxin-Avd3j OS=Nephila clavipes OX=2585209 GN=NCL1_61548 PE=4 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 1.774e-11
Identity = 26/39 (66.67%), Postives = 33/39 (84.62%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C+A +PR+YYN  T KCE+FIYGGC+GN NNFQ+ +DCE
Sbjct:   43 CKAAMPRFYYNKNTKKCERFIYGGCKGNNNNFQTLEDCE 81

[Close]

BLAST of U-actitoxin-Avd3j vs. TrEMBL
Match: H9GVY4 (Uncharacterized protein OS=Anolis carolinensis OX=28377 PE=4 SV=1)

HSP 1 Score: 64.6994 bits (156), Expect = 4.029e-11
Identity = 27/50 (54.00%), Postives = 39/50 (78.00%), Query Frame = 3

Query:   12 YMLPSKE*RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            ++LP+      C+A++PRY+YN K+ +CEKFIYGGC GN+NNF++ KDC 
Sbjct:  139 HLLPNP---GPCRAVVPRYFYNPKSNRCEKFIYGGCHGNKNNFETLKDCH 185

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Cavefish
Match: lrp11 (LDL receptor related protein 11 [Source:NCBI gene;Acc:103032685])

HSP 1 Score: 56.9954 bits (136), Expect = 2.489e-11
Identity = 19/38 (50.00%), Postives = 28/38 (73.68%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+   PR+YY++  G+C+ F+YGGC+GN+NNF    DC
Sbjct:  426 CRGTFPRWYYDAAAGECKHFLYGGCKGNRNNFLQQTDC 463

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Cavefish
Match: ENSAMXT00000053501.1 (pep primary_assembly:Astyanax_mexicanus-2.0:12:31379453:31384888:1 gene:ENSAMXG00000037311.1 transcript:ENSAMXT00000053501.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 52.373 bits (124), Expect = 5.860e-11
Identity = 20/38 (52.63%), Postives = 30/38 (78.95%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A++PR+Y+  + G+C  FIYGGC GN+NNF+S + C
Sbjct:   15 CRAMLPRWYFVKEEGRCAPFIYGGCGGNRNNFESEEYC 52

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Cavefish
Match: lrp11 (LDL receptor related protein 11 [Source:NCBI gene;Acc:103032685])

HSP 1 Score: 55.4546 bits (132), Expect = 8.445e-11
Identity = 19/38 (50.00%), Postives = 28/38 (73.68%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+   PR+YY++  G+C+ F+YGGC+GN+NNF    DC
Sbjct:  426 CRGTFPRWYYDAAAGECKHFLYGGCKGNRNNFLQQTDC 463

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Cavefish
Match: appb (amyloid beta A4 protein-like [Source:NCBI gene;Acc:103046668])

HSP 1 Score: 53.9138 bits (128), Expect = 3.760e-10
Identity = 19/41 (46.34%), Postives = 30/41 (73.17%), Query Frame = 3

Query:   36 RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            R  C+A + R+Y+ ++TG+C  F +GGC GN+NNF+S + C
Sbjct:  317 RGPCRATLSRWYFVAETGRCAPFSFGGCGGNRNNFESEEYC 357

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Cavefish
Match: appb (amyloid beta A4 protein-like [Source:NCBI gene;Acc:103046668])

HSP 1 Score: 53.5286 bits (127), Expect = 4.105e-10
Identity = 19/41 (46.34%), Postives = 30/41 (73.17%), Query Frame = 3

Query:   36 RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            R  C+A + R+Y+ ++TG+C  F +GGC GN+NNF+S + C
Sbjct:  317 RGPCRATLSRWYFVAETGRCAPFSFGGCGGNRNNFESEEYC 357

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005043.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005043.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.8398 bits (133), Expect = 9.250e-12
Identity = 23/38 (60.53%), Postives = 27/38 (71.05%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C A+IPR++YN KT  CE F YGGC GN NNF S + C
Sbjct:  175 CTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSC 212

HSP 2 Score: 50.8322 bits (120), Expect = 6.128e-10
Identity = 20/43 (46.51%), Postives = 32/43 (74.42%), Query Frame = 3

Query:   39 ALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQN 167
             +C+A++ RY++N  +G CE+F YGGC+GN NNF+ +  C Q+
Sbjct:   81 GVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQH 123

HSP 3 Score: 48.1358 bits (113), Expect = 5.739e-9
Identity = 21/38 (55.26%), Postives = 27/38 (71.05%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A +PR +YN  T +CE F YGGC GN NNF+S  +C
Sbjct:   12 CRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAEC 49

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005038.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005038.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 9.925e-12
Identity = 23/38 (60.53%), Postives = 27/38 (71.05%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C A+IPR++YN KT  CE F YGGC GN NNF S + C
Sbjct:  176 CTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSC 213

HSP 2 Score: 50.8322 bits (120), Expect = 6.294e-10
Identity = 20/43 (46.51%), Postives = 32/43 (74.42%), Query Frame = 3

Query:   39 ALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQN 167
             +C+A++ RY++N  +G CE+F YGGC+GN NNF+ +  C Q+
Sbjct:   82 GVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQH 124

HSP 3 Score: 48.1358 bits (113), Expect = 5.887e-9
Identity = 21/38 (55.26%), Postives = 27/38 (71.05%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A +PR +YN  T +CE F YGGC GN NNF+S  +C
Sbjct:   12 CRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAEC 49

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Sea Lamprey
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:ZFIN;Acc:ZDB-GENE-060503-38])

HSP 1 Score: 54.299 bits (129), Expect = 3.730e-11
Identity = 23/48 (47.92%), Postives = 33/48 (68.75%), Query Frame = 3

Query:   18 LPSKE*RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            LP+K     C+A  PRY++N  T +CE FIYGGC  N+NNF++ ++C 
Sbjct:   29 LPAKP--GDCRAAFPRYFFNRSTLRCESFIYGGCHSNENNFETMQECR 74

HSP 2 Score: 45.4394 bits (106), Expect = 5.002e-8
Identity = 19/38 (50.00%), Postives = 24/38 (63.16%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A I RY+YN   G C  F+YGGC GN N F+  + C
Sbjct:   96 CRAHITRYFYNMTLGMCMPFVYGGCGGNNNRFEDMESC 133

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Sea Lamprey
Match: WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30912])

HSP 1 Score: 48.521 bits (114), Expect = 6.165e-9
Identity = 21/41 (51.22%), Postives = 27/41 (65.85%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQN 167
            C+    R+ YN    +C+ FIYGGC GN+NNFQS + CE N
Sbjct:  383 CKQWALRWAYNPLIKRCQSFIYGGCEGNENNFQSQELCEDN 423

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009465.1 (pep scaffold:Pmarinus_7.0:GL478507:22936:25713:-1 gene:ENSPMAG00000008558.1 transcript:ENSPMAT00000009465.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 45.8246 bits (107), Expect = 4.463e-8
Identity = 18/38 (47.37%), Postives = 25/38 (65.79%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+    R+ Y++ T  C++F YGGCRGNQNNF    +C
Sbjct:   10 CRGSFTRWTYDAATSTCKEFTYGGCRGNQNNFLEEAEC 47

HSP 2 Score: 41.2022 bits (95), Expect = 1.927e-6
Identity = 16/38 (42.11%), Postives = 25/38 (65.79%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+    R+ Y++++G C++F YGGC GN NNF    +C
Sbjct:  175 CRGSFTRWTYDAESGHCKEFTYGGCGGNFNNFLEETEC 212

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Nematostella
Match: EDO47795 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL41])

HSP 1 Score: 59.3066 bits (142), Expect = 3.267e-14
Identity = 23/41 (56.10%), Postives = 33/41 (80.49%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQN 167
            C A +PR+YYN+K  +C+KF+YGGCRGN N F+S + CE++
Sbjct:   11 CSAYVPRWYYNAKHRRCQKFVYGGCRGNANRFKSHRSCERS 51

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Nematostella
Match: EDO29819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2J6])

HSP 1 Score: 57.7658 bits (138), Expect = 1.782e-13
Identity = 22/40 (55.00%), Postives = 33/40 (82.50%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            C+A +PR ++NS++GKCE FIYGGC GN NNF + ++C++
Sbjct:   23 CRAAMPRVFFNSQSGKCEDFIYGGCGGNANNFHTMEECKK 62

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Nematostella
Match: EDO38284 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDB9])

HSP 1 Score: 52.7582 bits (125), Expect = 1.318e-11
Identity = 22/39 (56.41%), Postives = 29/39 (74.36%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCE 161
            C A I R+YYN+K GKC+ F++GGC  N NNF++ K CE
Sbjct:   22 CMASIERFYYNAKIGKCQSFVFGGCLPNGNNFKTRKACE 60

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Nematostella
Match: EDO41696 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 50.8322 bits (120), Expect = 5.975e-11
Identity = 20/40 (50.00%), Postives = 31/40 (77.50%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            C+A   R++YN  + KC++F+YGGC+GN NNF+S  +CE+
Sbjct:   11 CRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEK 50

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Nematostella
Match: EDO26263 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 50.8322 bits (120), Expect = 5.975e-11
Identity = 20/40 (50.00%), Postives = 31/40 (77.50%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            C+A   R++YN  + KC++F+YGGC+GN NNF+S  +CE+
Sbjct:   11 CRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEK 50

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Medaka
Match: APP (amyloid-beta A4 protein [Source:NCBI gene;Acc:101162104])

HSP 1 Score: 57.7658 bits (138), Expect = 1.424e-11
Identity = 19/38 (50.00%), Postives = 32/38 (84.21%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+A++PR++++ + G+C +FIYGGC GN+NNF+S + C
Sbjct:  339 CRALLPRWFFDREEGRCVQFIYGGCGGNRNNFESEEYC 376

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Medaka
Match: lrp11 (low-density lipoprotein receptor-related protein 11 [Source:NCBI gene;Acc:101175213])

HSP 1 Score: 56.225 bits (134), Expect = 4.851e-11
Identity = 20/38 (52.63%), Postives = 27/38 (71.05%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+   PR+YY+  TG+C+ F+YGGC+GN NNF    DC
Sbjct:  403 CKGTFPRWYYDQNTGECKHFLYGGCQGNHNNFLQELDC 440

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Medaka
Match: ENSORLT00000012975.2 (pep primary_assembly:ASM223467v1:12:15740273:15760140:1 gene:ENSORLG00000010354.2 transcript:ENSORLT00000012975.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 54.299 bits (129), Expect = 9.996e-11
Identity = 24/42 (57.14%), Postives = 29/42 (69.05%), Query Frame = 3

Query:   39 ALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
             LC     RY+YN + G+CE FIYGGC GNQNNF + K+C Q
Sbjct:   80 GLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKECLQ 121

HSP 2 Score: 54.299 bits (129), Expect = 9.996e-11
Identity = 24/42 (57.14%), Postives = 29/42 (69.05%), Query Frame = 3

Query:   39 ALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
             LC     RY+YN + G+CE FIYGGC GNQNNF + K+C Q
Sbjct:  132 GLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKECLQ 173

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Medaka
Match: ENSORLT00000042019.1 (pep primary_assembly:ASM223467v1:12:15740119:15780496:1 gene:ENSORLG00000010354.2 transcript:ENSORLT00000042019.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.5286 bits (127), Expect = 3.778e-10
Identity = 24/42 (57.14%), Postives = 29/42 (69.05%), Query Frame = 3

Query:   39 ALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
             LC     RY+YN + G+CE FIYGGC GNQNNF + K+C Q
Sbjct:   88 GLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKECLQ 129

HSP 2 Score: 52.373 bits (124), Expect = 8.948e-10
Identity = 23/40 (57.50%), Postives = 28/40 (70.00%), Query Frame = 3

Query:   39 ALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
             LC     RY+YN + G+CE FIYGGC GNQNNF + K+C
Sbjct:   32 GLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKEC 71

HSP 3 Score: 45.0542 bits (105), Expect = 4.292e-7
Identity = 20/38 (52.63%), Postives = 27/38 (71.05%), Query Frame = 3

Query:   45 CQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
            C+    RY+YN K  +CE FIYG C GNQNNF++ ++C
Sbjct:  142 CECYSERYFYNFKKRRCEIFIYGCCNGNQNNFETEQEC 179

[Close]

BLAST of U-actitoxin-Avd3j vs. Ensembl Medaka
Match: wfikkn2a (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:NCBI gene;Acc:101168544])

HSP 1 Score: 53.5286 bits (127), Expect = 4.611e-10
Identity = 25/49 (51.02%), Postives = 34/49 (69.39%), Query Frame = 3

Query:   18 LPSKE*RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQ 164
            LPS +    C+A  PR+ Y+S   KC+ F+YGGC GN+NNF+S + CEQ
Sbjct:  390 LPSLQ--GPCKAYEPRWAYSSTLKKCQSFVYGGCGGNENNFESKEACEQ 436

[Close]

BLAST of U-actitoxin-Avd3j vs. Planmine SMEST
Match: SMESG000037997.1 (SMESG000037997.1)

HSP 1 Score: 61.6178 bits (148), Expect = 1.529e-14
Identity = 27/46 (58.70%), Postives = 35/46 (76.09%), Query Frame = 3

Query:   36 RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLC 173
            + LC+A  PRY+YN  + KCE+FIYGGC  N NNF++ KDC Q+LC
Sbjct:   33 KGLCEAYFPRYFYNDTSEKCERFIYGGCGANGNNFKTLKDC-QDLC 77

[Close]

BLAST of U-actitoxin-Avd3j vs. Planmine SMEST
Match: SMESG000038002.1 (SMESG000038002.1)

HSP 1 Score: 61.2326 bits (147), Expect = 2.194e-14
Identity = 27/46 (58.70%), Postives = 35/46 (76.09%), Query Frame = 3

Query:   36 RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLC 173
            + LC+A  PRY+YN  + KCE+FIYGGC  N NNF++ KDC Q+LC
Sbjct:   33 KGLCEAYFPRYFYNDTSEKCERFIYGGCGANGNNFKTLKDC-QDLC 77

[Close]

BLAST of U-actitoxin-Avd3j vs. Planmine SMEST
Match: SMESG000037996.1 (SMESG000037996.1)

HSP 1 Score: 61.2326 bits (147), Expect = 7.548e-14
Identity = 28/46 (60.87%), Postives = 36/46 (78.26%), Query Frame = 3

Query:   36 RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLC 173
            + LC+A IPRY+YN  + KCE+FIYGGC  N NNF++ KDC Q+LC
Sbjct:   33 KGLCKAYIPRYFYNDTSEKCERFIYGGCGANGNNFKTLKDC-QDLC 77

HSP 2 Score: 56.9954 bits (136), Expect = 3.230e-12
Identity = 26/46 (56.52%), Postives = 33/46 (71.74%), Query Frame = 3

Query:   36 RALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDCEQNLC 173
            +  C+A IPRY+YN  + KCE+FIYGGC  N NNF+  KDC Q+ C
Sbjct:   91 KGFCKAYIPRYFYNDTSEKCERFIYGGCGANGNNFKILKDC-QDFC 135

[Close]

BLAST of U-actitoxin-Avd3j vs. Planmine SMEST
Match: SMESG000013910.1 (SMESG000013910.1)

HSP 1 Score: 58.9214 bits (141), Expect = 1.201e-13
Identity = 24/40 (60.00%), Postives = 32/40 (80.00%), Query Frame = 3

Query:   39 ALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
             LC+   PRY++N +TGKCEKFIYGGC+GN+NNF +  +C
Sbjct:   27 GLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIEC 66

[Close]

BLAST of U-actitoxin-Avd3j vs. Planmine SMEST
Match: SMESG000013915.1 (SMESG000013915.1)

HSP 1 Score: 58.9214 bits (141), Expect = 2.036e-13
Identity = 24/40 (60.00%), Postives = 32/40 (80.00%), Query Frame = 3

Query:   39 ALCQAIIPRYYYNSKTGKCEKFIYGGCRGNQNNFQSSKDC 158
             LC+   PRY++N +TGKCEKFIYGGC+GN+NNF +  +C
Sbjct:   52 GLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIEC 91

The following BLAST results are available for this feature:

BLAST of U-actitoxin-Avd3j vs. Ensembl Human
BLAST of U-actitoxin-Avd3j vs. Ensembl Celegans
BLAST of U-actitoxin-Avd3j vs. Ensembl Fly
BLAST of U-actitoxin-Avd3j vs. Ensembl Zebrafish
BLAST of U-actitoxin-Avd3j vs. Ensembl Xenopus
BLAST of U-actitoxin-Avd3j vs. Ensembl Mouse
BLAST of U-actitoxin-Avd3j vs. UniProt/SwissProt
BLAST of U-actitoxin-Avd3j vs. TrEMBL
BLAST of U-actitoxin-Avd3j vs. Ensembl Cavefish
BLAST of U-actitoxin-Avd3j vs. Ensembl Sea Lamprey
BLAST of U-actitoxin-Avd3j vs. Ensembl Yeast
BLAST of U-actitoxin-Avd3j vs. Ensembl Nematostella
BLAST of U-actitoxin-Avd3j vs. Ensembl Medaka
BLAST of U-actitoxin-Avd3j vs. Planmine SMEST

BLAST of U-actitoxin-Avd3j vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
WFIKKN2	4.069e-12	56.10	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
WFIKKN2	8.757e-12	56.10	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
APLP2	1.435e-11	55.26	amyloid beta precursor like protein 2 [Source:HGNC...	[more]
APLP2	1.435e-11	55.26	amyloid beta precursor like protein 2 [Source:HGNC...	[more]
APLP2	1.449e-11	55.26	amyloid beta precursor like protein 2 [Source:HGNC...	[more]

BLAST of U-actitoxin-Avd3j vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mlt-11	3.243e-10	47.62	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	3.243e-10	47.62	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	3.646e-10	47.62	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]
mlt-11	6.368e-10	47.62	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	7.667e-10	47.62	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]

BLAST of U-actitoxin-Avd3j vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG13748	1.971e-11	45.83	gene:FBgn0033355 transcript:FBtr0088656	[more]
CG3604	6.835e-11	57.50	gene:FBgn0031562 transcript:FBtr0077545	[more]
CG3604	6.835e-11	57.50	gene:FBgn0031562 transcript:FBtr0346581	[more]
IM33	1.347e-10	55.00	gene:FBgn0031561 transcript:FBtr0077546	[more]
IM33	1.347e-10	55.00	gene:FBgn0031561 transcript:FBtr0345610	[more]

BLAST of U-actitoxin-Avd3j vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tfpia	4.375e-10	52.50	tissue factor pathway inhibitor a [Source:ZFIN;Acc...	[more]
tfpia	4.631e-10	52.50	tissue factor pathway inhibitor a [Source:ZFIN;Acc...	[more]
appb	7.167e-10	47.37	amyloid beta (A4) precursor protein b [Source:ZFIN...	[more]
aplp2	7.171e-10	50.00	amyloid beta (A4) precursor-like protein 2 [Source...	[more]
appb	7.825e-10	47.37	amyloid beta (A4) precursor protein b [Source:ZFIN...	[more]

BLAST of U-actitoxin-Avd3j vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gtf2e2	4.638e-11	57.89	general transcription factor IIE subunit 2 [Source...	[more]
gtf2e2	5.164e-11	57.89	general transcription factor IIE subunit 2 [Source...	[more]
gtf2e2	5.637e-11	57.89	general transcription factor IIE subunit 2 [Source...	[more]
gtf2e2	6.040e-11	57.89	general transcription factor IIE subunit 2 [Source...	[more]
gtf2e2	6.095e-11	57.89	general transcription factor IIE subunit 2 [Source...	[more]

BLAST of U-actitoxin-Avd3j vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Spint3	6.321e-13	64.10	serine peptidase inhibitor, Kunitz type, 3 [Source...	[more]
Wfikkn2	5.724e-12	56.10	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
Aplp2	9.379e-12	55.26	amyloid beta (A4) precursor-like protein 2 [Source...	[more]
Aplp2	2.210e-11	55.26	amyloid beta (A4) precursor-like protein 2 [Source...	[more]
Spint2	2.149e-10	55.26	serine protease inhibitor, Kunitz type 2 [Source:M...	[more]

BLAST of U-actitoxin-Avd3j vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8WPI3\|BOOG2_RHIMP	1.002e-13	53.06	Boophilin-G2 OS=Rhipicephalus microplus OX=6941 GN...	[more]
sp\|P0DN09\|VKT5_ANEVI	1.221e-13	65.00	U-actitoxin-Avd3h OS=Anemonia viridis OX=51769 PE=...	[more]
sp\|P0DN12\|VKT8_ANEVI	1.407e-13	60.00	U-actitoxin-Avd3k OS=Anemonia viridis OX=51769 PE=...	[more]
sp\|Q9TWG0\|VKT1_ANESU	1.510e-13	58.00	KappaPI-actitoxin-Avd3b OS=Anemonia sulcata OX=610...	[more]
sp\|Q9TWF9\|VKT2_ANESU	1.578e-13	60.00	KappaPI-actitoxin-Avd3c OS=Anemonia sulcata OX=610...	[more]

BLAST of U-actitoxin-Avd3j vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
I1ZII0	4.292e-18	90.24	Serine protease inhibitor-1 (Fragment) OS=Schmidte...	[more]
A0A2P6KJJ0	2.950e-12	74.36	BPTI/Kunitz domain-containing protein OS=Nephila c...	[more]
H9GB43	6.148e-12	54.00	Uncharacterized protein OS=Anolis carolinensis OX=...	[more]
A0A2P6JVV9	1.774e-11	66.67	U-actitoxin-Avd3j OS=Nephila clavipes OX=2585209 G...	[more]
H9GVY4	4.029e-11	54.00	Uncharacterized protein OS=Anolis carolinensis OX=...	[more]

BLAST of U-actitoxin-Avd3j vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrp11	2.489e-11	50.00	LDL receptor related protein 11 [Source:NCBI gene;...	[more]
ENSAMXT00000053501.1	5.860e-11	52.63	pep primary_assembly:Astyanax_mexicanus-2.0:12:313...	[more]
lrp11	8.445e-11	50.00	LDL receptor related protein 11 [Source:NCBI gene;...	[more]
appb	3.760e-10	46.34	amyloid beta A4 protein-like [Source:NCBI gene;Acc...	[more]
appb	4.105e-10	46.34	amyloid beta A4 protein-like [Source:NCBI gene;Acc...	[more]

BLAST of U-actitoxin-Avd3j vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000005043.1	9.250e-12	60.53	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
ENSPMAT00000005038.1	9.925e-12	60.53	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
tfpi2	3.730e-11	47.92	tissue factor pathway inhibitor 2 [Source:ZFIN;Acc...	[more]
WFIKKN1	6.165e-9	51.22	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
ENSPMAT00000009465.1	4.463e-8	47.37	pep scaffold:Pmarinus_7.0:GL478507:22936:25713:-1 ...	[more]

BLAST of U-actitoxin-Avd3j vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of U-actitoxin-Avd3j vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO47795	3.267e-14	56.10	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO29819	1.782e-13	55.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38284	1.318e-11	56.41	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41696	5.975e-11	50.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO26263	5.975e-11	50.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of U-actitoxin-Avd3j vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
APP	1.424e-11	50.00	amyloid-beta A4 protein [Source:NCBI gene;Acc:1011...	[more]
lrp11	4.851e-11	52.63	low-density lipoprotein receptor-related protein 1...	[more]
ENSORLT00000012975.2	9.996e-11	57.14	pep primary_assembly:ASM223467v1:12:15740273:15760...	[more]
ENSORLT00000042019.1	3.778e-10	57.14	pep primary_assembly:ASM223467v1:12:15740119:15780...	[more]
wfikkn2a	4.611e-10	51.02	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]

BLAST of U-actitoxin-Avd3j vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000037997.1	1.529e-14	58.70	SMESG000037997.1	[more]
SMESG000038002.1	2.194e-14	58.70	SMESG000038002.1	[more]
SMESG000037996.1	7.548e-14	60.87	SMESG000037996.1	[more]
SMESG000013910.1	1.201e-13	60.00	SMESG000013910.1	[more]
SMESG000013915.1	2.036e-13	60.00	SMESG000013915.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence

transcript sequence

>SMED30002548 ID=SMED30002548|Name=U-actitoxin-Avd3j|organism=Schmidtea mediterranea sexual|type=transcript|length=180bp
ATGACAGATAGTATATGCTCCCTTCCAAAGAATGAAGGGCCCTTTGCCAA
GCTATTATTCCAAGATATTATTATAATTCAAAGACTGGAAAATGCGAAAA
ATTCATTTATGGAGGCTGCAGAGGAAATCAAAATAATTTTCAAAGTAGCA
AGGATTGTGAACAAAATTTATGTAATATAA

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005576	extracellular region
GO:0042151	nematocyst

Vocabulary: **biological process**
Term	Definition
GO:0010466	negative regulation of peptidase activity
GO:0006508	proteolysis
GO:0010951	negative regulation of endopeptidase activity

Vocabulary: **molecular function**
Term	Definition
GO:0030414	peptidase inhibitor activity
GO:0090729	toxin activity
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0008233	peptidase activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000136	whole organism

Vocabulary: **INTERPRO**
Term	Definition
IPR036880	Kunitz_BPTI_sf
IPR002223	Kunitz_BPTI
IPR020901	Prtase_inh_Kunz-CS

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PRINTS	PR00759	BASICPTASE	coord: 31..41 score: 63.89 coord: 3..17 score: 38.44 coord: 41..50 score: 31.65
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	SMART	SM00131	KU_2	coord: 4..50 e-value: 6.0E-17 score: 72.3
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PFAM	PF00014	Kunitz_BPTI	coord: 5..49 e-value: 5.0E-20 score: 71.5
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PROSITE	PS50279	BPTI_KUNITZ_2	coord: 6..50 score: 13.854
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	CDD	cd00109	KU	coord: 4..48 e-value: 2.54234E-20 score: 72.6678
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	GENE3D	G3DSA:4.10.410.10		coord: 2..50 e-value: 2.3E-23 score: 83.7
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	SUPERFAMILY	SSF57362	BPTI-like	coord: 2..49
None	No IPR available	PANTHER	PTHR10083	KUNITZ-TYPE PROTEASE INHIBITOR-RELATED	coord: 5..48
None	No IPR available	PANTHER	PTHR10083:SF328	TISSUE FACTOR PATHWAY INHIBITOR	coord: 5..48

Main menu

U-actitoxin-Avd3j

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

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