Transient receptor potential cation channel subfamily M member 6
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002539 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Human
Match: TRPM1 (transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146]) HSP 1 Score: 296.975 bits (759), Expect = 2.275e-81 Identity = 323/1193 (27.07%), Postives = 533/1193 (44.68%), Query Frame = 1
Query: 265 MQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSH-------------KENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDIFIEASRRVKEK--VSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKN---VLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFS--------GDISLSNDE----------------------------------------------WAAFLKDSIITG----KVKFIELFLENVSNIQDFLTANILKELYET--CPKST-------------------------------------------NFRKTFLRLIGRPFSKGLNDVKELLSKMIGFY--EYPCSE----------------NDSIKHPFQELF----LWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRD---TDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN---FFSCILCIIFPFLI---------------SKRTEFTKDFKTCQSESFPDF--------NEDNCRTS--ISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFG-VLNLGNTVYFTWCNASTNYEVSNE-------CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPF 3273
M +++I F EC + + K+ +++C CG+ H +ENK E WS + PT S+G +EF G +N + ++RVSY K D ++ L+ W++ L ISV GG +F+M K K +F +GLIKAA+TT A I T G++ G+ S +GDA++ S K + +GIAPWG V+N+ L V+ +SN + K LN +HTH+I D+G T K G R+ LE IS QK R+ G+P+V L+VEGG ++ ++E+ + +V+C+G+G+ASDI+ A HK G+ + ES + V +K + ++ HQ+ I + +K + L+TVF + S +D++ AIL +L+K ++ QLSL L WNRVDI + +IF G ++ D W L+ +++ +V F++L +EN N+Q FLT L+ELY T P +T NFR + L G K L K++G E P +D FQ F +WAVLM++QK A F W + +ES+ ALVA ++YK S D S+ L+ F LA++L+++ + D+++A L+ + +NW +CL+LA + F+++ Q + W + I+ I+ P I SK E K+ + +++ D NE + S I +K+ FY AP KF ++ +++ +++ F+YV+L M ++ E + + Y+V + L+K EI S ++ +IK W +WN D++ I ++ +LR Q N Y + + IY + + +Y+++L + +K LGP + M+ K++ ++L F I+L+ L+S+GV QA +P+ SW NI PY+ ++G V +Y N + +E C +L P L A Y+++ NILL+N+LIA + ++ S +WK+ Y LI+ ++D+P+LP P
Sbjct: 1 MGQKSWIEKTFCKRECIFVIPSTKD----SNRCCCGQFTNQHIPPLPSATPSKNEEENKQVETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAM--YIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVISHVGDALKDHSS------KSRGRVCAIGIAPWGIVENKEDLVGKDVTRVYQTMSNPLSKLS--VLNNSHTHFILADNG-----TLGKYGAEVKLRRLLEKHISLQKINTRLGQGVPLVGLVVEGGPNVVSIVLEYLQEEPPIPVVICDGSGRASDILSFA----------HKYCEEGGI--INESLREQLLVTIQKTFNYNKAQSHQL---FAIIMECMKKKELVTVFRMGSEGQQDIEMAILTALLKGTNV-------SAPDQLSLALAWNRVDIARSQIFVFGPHWPPLGSLAPPTDSKATEKEKKPPMATTKGGRGKGKGKKKGKVKEEVEEETDPRKIELLNWVNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTRLGPPNTLHLLVRDVKKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKNFRTLYNNLFGPKRPKAL--------KLLGMEDDEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEESMAKALVACKLYKAMAHESSESDLVDDISQDLDNNSKDFGQLALELLDQSYKHDEQIAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILLPPTILFLEFRTYDDFSYQTSKENEDGKEKEEENTDANADAGSRKGDEENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVILVRMDGWP-SLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQ-EYWNITDLVAISTFMIGAILRLQ---NQPY------MGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEINPPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPM 1133
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Human
Match: TRPM1 (transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146]) HSP 1 Score: 295.434 bits (755), Expect = 7.655e-81 Identity = 322/1193 (26.99%), Postives = 534/1193 (44.76%), Query Frame = 1
Query: 265 MQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSH-------------KENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDIFIEASRRVKEK--VSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKN---VLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFS--------GDISLSNDE----------------------------------------------WAAFLKDSIITG----KVKFIELFLENVSNIQDFLTANILKELYET--CPKST-------------------------------------------NFRKTFLRLIGRPFSKGLNDVKELLSKMIGFY--EYPCSE----------------NDSIKHPFQELF----LWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRD---TDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN---FFSCILCIIFPFLI---------------SKRTEFTKDFKTCQSESFPDF--------NEDNCRTS--ISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFG-VLNLGNTVYFTWCNASTNYEVSNE-------CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPF 3273
M +++I F EC + ++K+ +++C CG+ H +E+K E WS + PT S+G +EF G +N + ++RVSY K D ++ L+ W++ L ISV GG +F+M K K +F +GLIKAA+TT A I T G++ G+ S +GDA++ S K + +GIAPWG V+N+ L V+ +SN + K LN +HTH+I D+G T K G R+ LE IS QK R+ G+P+V L+VEGG ++ ++E+ + +V+C+G+G+ASDI+ A HK G+ + ES + V +K + ++ HQ+ I + +K + L+TVF + S +D++ AIL +L+K ++ QLSL L WNRVDI + +IF G ++ D W L+ +++ +V F++L +EN N+Q FLT L+ELY T P +T NFR + L G K L K++G E P +D FQ F +WAVLM++QK A F W + +ES+ ALVA ++YK S D S+ L+ F LA++L+++ + D+++A L+ + +NW +CL+LA + F+++ Q + W + I+ I+ P I SK E K+ + +++ D NE + S I +K+ FY AP KF ++ +++ +++ F+YV+L M ++ E + + Y+V + L+K EI S ++ +IK W +WN D++ I ++ +LR Q N Y + + IY + + +Y+++L + +K LGP + M+ K++ ++L F I+L+ L+S+GV QA +P+ SW NI PY+ ++G V +Y N + +E C +L P L A Y+++ NILL+N+LIA + ++ S +WK+ Y LI+ ++D+P+LP P
Sbjct: 1 MGQKSWIEKTFCKRECIFVIPSMKD----SNRCCCGQFTNQHIPPLPSATPSKNEEESKQVETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAM--YIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVISHVGDALKDHSS------KSRGRVCAIGIAPWGIVENKEDLVGKDVTRVYQTMSNPLSKLS--VLNNSHTHFILADNG-----TLGKYGAEVKLRRLLEKHISLQKINTRLGQGVPLVGLVVEGGPNVVSIVLEYLQEEPPIPVVICDGSGRASDILSFA----------HKYCEEGGI--INESLREQLLVTIQKTFNYNKAQSHQL---FAIIMECMKKKELVTVFRMGSEGQQDIEMAILTALLKGTNV-------SAPDQLSLALAWNRVDIARSQIFVFGPHWPPLGSLAPPTDSKATEKEKKPPMATTKGGRGKGKGKKKGKVKEEVEEETDPRKIELLNWVNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTRLGPPNTLHLLVRDVKKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKNFRTLYNNLFGPKRPKAL--------KLLGMEDDEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEESMAKALVACKLYKAMAHESSESDLVDDISQDLDNNSKDFGQLALELLDQSYKHDEQIAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILLPPTILFLEFRTYDDFSYQTSKENEDGKEKEEENTDANADAGSRKGDEENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVILVRMDGWP-SLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQ-EYWNITDLVAISTFMIGAILRLQ---NQPY------MGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEINPPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPM 1133
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Human
Match: TRPM1 (transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146]) HSP 1 Score: 293.123 bits (749), Expect = 4.696e-80 Identity = 317/1162 (27.28%), Postives = 519/1162 (44.66%), Query Frame = 1
Query: 358 KCSCGEIKKSH-------------KENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDIFIEASRRVKEK--VSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKN---VLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFS--------GDISLSNDE----------------------------------------------WAAFLKDSIITG----KVKFIELFLENVSNIQDFLTANILKELYET--CPKST-------------------------------------------NFRKTFLRLIGRPFSKGLNDVKELLSKMIGFY--EYPCSE----------------NDSIKHPFQELF----LWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRD---TDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN---FFSCILCIIFPFLI---------------SKRTEFTKDFKTCQSESFPDF--------NEDNCRTS--ISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFG-VLNLGNTVYFTWCNASTNYEVSNE-------CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPF 3273
+C CG+ H +ENK E WS + PT S+G +EF G +N + ++RVSY K D ++ L+ W++ L ISV GG +F+M K K +F +GLIKAA+TT A I T G++ G+ S +GDA++ S K + +GIAPWG V+N+ L V+ +SN + K LN +HTH+I D+G T K G R+ LE IS QK R+ G+P+V L+VEGG ++ ++E+ + +V+C+G+G+ASDI+ A HK G+ + ES + V +K + ++ HQ+ I + +K + L+TVF + S +D++ AIL +L+K ++ QLSL L WNRVDI + +IF G ++ D W L+ +++ +V F++L +EN N+Q FLT L+ELY T P +T NFR + L G K L K++G E P +D FQ F +WAVLM++QK A F W + +ES+ ALVA ++YK S D S+ L+ F LA++L+++ + D+++A L+ + +NW +CL+LA + F+++ Q + W + I+ I+ P I SK E K+ + +++ D NE + S I +K+ FY AP KF ++ +++ +++ F+YV+L M ++ E + + Y+V + L+K EI S ++ +IK W +WN D++ I ++ +LR Q N Y + + IY + + +Y+++L + +K LGP + M+ K++ ++L F I+L+ L+S+GV QA +P+ SW NI PY+ ++G V +Y N + +E C +L P L A Y+++ NILL+N+LIA + ++ S +WK+ Y LI+ ++D+P+LP P
Sbjct: 6 RCCCGQFTNQHIPPLPSATPSKNEEENKQVETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAM--YIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVISHVGDALKDHSS------KSRGRVCAIGIAPWGIVENKEDLVGKDVTRVYQTMSNPLSKLS--VLNNSHTHFILADNG-----TLGKYGAEVKLRRLLEKHISLQKINTRLGQGVPLVGLVVEGGPNVVSIVLEYLQEEPPIPVVICDGSGRASDILSFA----------HKYCEEGGI--INESLREQLLVTIQKTFNYNKAQSHQL---FAIIMECMKKKELVTVFRMGSEGQQDIEMAILTALLKGTNV-------SAPDQLSLALAWNRVDIARSQIFVFGPHWPPLGSLAPPTDSKATEKEKKPPMATTKGGRGKGKGKKKGKVKEEVEEETDPRKIELLNWVNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTRLGPPNTLHLLVRDVKKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKNFRTLYNNLFGPKRPKAL--------KLLGMEDDEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEESMAKALVACKLYKAMAHESSESDLVDDISQDLDNNSKDFGQLALELLDQSYKHDEQIAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILLPPTILFLEFRTYDDFSYQTSKENEDGKEKEEENTDANADAGSRKGDEENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVILVRMDGWP-SLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQ-EYWNITDLVAISTFMIGAILRLQ---NQPY------MGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEINPPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPM 1111
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Human
Match: TRPM1 (transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146]) HSP 1 Score: 291.967 bits (746), Expect = 5.465e-80 Identity = 316/1164 (27.15%), Postives = 521/1164 (44.76%), Query Frame = 1
Query: 352 NSKCSCGEIKKSH-------------KENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDIFIEASRRVKEK--VSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKN---VLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFS--------GDISLSNDE----------------------------------------------WAAFLKDSIITG----KVKFIELFLENVSNIQDFLTANILKELYET--CPKST-------------------------------------------NFRKTFLRLIGRPFSKGLNDVKELLSKMIGFY--EYPCSE----------------NDSIKHPFQELF----LWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRD---TDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN---FFSCILCIIFPFLI---------------SKRTEFTKDFKTCQSESFPDF--------NEDNCRTS--ISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFG-VLNLGNTVYFTWCNASTNYEVSNE-------CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPF 3273
+++C CG+ H +E+K E WS + PT S+G +EF G +N + ++RVSY K D ++ L+ W++ L ISV GG +F+M K K +F +GLIKAA+TT A I T G++ G+ S +GDA++ S K + +GIAPWG V+N+ L V+ +SN + K LN +HTH+I D+G T K G R+ LE IS QK R+ G+P+V L+VEGG ++ ++E+ + +V+C+G+G+ASDI+ A HK G+ + ES + V +K + ++ HQ+ I + +K + L+TVF + S +D++ AIL +L+K ++ QLSL L WNRVDI + +IF G ++ D W L+ +++ +V F++L +EN N+Q FLT L+ELY T P +T NFR + L G K L K++G E P +D FQ F +WAVLM++QK A F W + +ES+ ALVA ++YK S D S+ L+ F LA++L+++ + D+++A L+ + +NW +CL+LA + F+++ Q + W + I+ I+ P I SK E K+ + +++ D NE + S I +K+ FY AP KF ++ +++ +++ F+YV+L M ++ E + + Y+V + L+K EI S ++ +IK W +WN D++ I ++ +LR Q N Y + + IY + + +Y+++L + +K LGP + M+ K++ ++L F I+L+ L+S+GV QA +P+ SW NI PY+ ++G V +Y N + +E C +L P L A Y+++ NILL+N+LIA + ++ S +WK+ Y LI+ ++D+P+LP P
Sbjct: 4 SNRCCCGQFTNQHIPPLPSATPSKNEEESKQVETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAM--YIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVISHVGDALKDHSS------KSRGRVCAIGIAPWGIVENKEDLVGKDVTRVYQTMSNPLSKLS--VLNNSHTHFILADNG-----TLGKYGAEVKLRRLLEKHISLQKINTRLGQGVPLVGLVVEGGPNVVSIVLEYLQEEPPIPVVICDGSGRASDILSFA----------HKYCEEGGI--INESLREQLLVTIQKTFNYNKAQSHQL---FAIIMECMKKKELVTVFRMGSEGQQDIEMAILTALLKGTNV-------SAPDQLSLALAWNRVDIARSQIFVFGPHWPPLGSLAPPTDSKATEKEKKPPMATTKGGRGKGKGKKKGKVKEEVEEETDPRKIELLNWVNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTRLGPPNTLHLLVRDVKKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKNFRTLYNNLFGPKRPKAL--------KLLGMEDDEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEESMAKALVACKLYKAMAHESSESDLVDDISQDLDNNSKDFGQLALELLDQSYKHDEQIAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILLPPTILFLEFRTYDDFSYQTSKENEDGKEKEEENTDANADAGSRKGDEENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVILVRMDGWP-SLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQ-EYWNITDLVAISTFMIGAILRLQ---NQPY------MGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEINPPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPM 1111
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Human
Match: TRPM3 (transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992]) HSP 1 Score: 271.937 bits (694), Expect = 2.296e-73 Identity = 336/1261 (26.65%), Postives = 555/1261 (44.01%), Query Frame = 1
Query: 523 FVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTV---HYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QK-----------------------QGDRVGI----PVVLLIVEGGHDI--FIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAA-----FLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTN---------------------------------------------FRKTFLRLIGR-----PFSKGLNDVKELLSKMIGFYEYPCSENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRD---TDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNI---NFFSCILCIIFPFLI--------------------------------------SKRTEFTKDFKTCQSESFPDFNEDNCRT-----SISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRW-SKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNE---------CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMP---FSTFVYIYQVLAFCYQKG------RCYNLSNSKKFEITKHNSKLH------IDKPMAFKHDTLNIFSNIKSDSDLNKLIKYFENYSQKFVIKNIAIEKQKSIKSGISRMEIRSKSIFKELENIQTKLNKI----QIKNVKKVQEGSFTNTNGEYQNITKQPKDSMALLLTSLNNNILVLQDEVNRIGQEV 3792
+VRVS+ K D ++ L+ +W++ L ISV GG +F++ K K +F +GLIKAA+TT A I T G+N G+ +GDA++ S K I +GIAPWG V+N+ L GR V + +SN + K LN H+H+I D+G T K G R+ LE IS QK Q D VGI PVV LIVEGG ++ + R V +VVC+G+G+ASDI+ AF HK G ++ ES ++ L + + Q + + +K + LITVF + S H+D+D AIL +L+K + QLSL L WNRVDI + +IF + +W + D+++ +V F++L +EN ++ FLT + L+ELY T +N FR + L G P +G K+ ++ + P E + PF EL +WAVLM++QK A FFW +E++ ALVA ++ K + + D S+ L F LAV+L+++ + D+++A L+ + +NW +CL+LA + F+++ Q + W + + IL I+ P I + E T ES +E+ ++ + K+ FY AP KF ++ +I +++ F+Y+VL M+R T E + + Y+ + ++K EI S ++ ++K W +WN D+I I+ V M+LR Q D+ FR + IY + + +Y+++L + +K LGP + M+ K++ +++ F I+L+ L+S+GV QA +P + SW NI PY+ ++G V+ + + E C +++P + A Y+++ NILL+N+LIA + ++ S +WK+ Y LI+ ++++P+LP P FS I+Q L ++K R Y L K F K+H I++ K D N +D + + EN S + N E++ S+K+ + ++IR + + + T L ++ + ++ K S T+ Y I +Q S N LQ+ ++ G+E
Sbjct: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHAS------KSRGKICTIGIAPWGIVENQEDL---IGRDVVRPYQTMSNPMSKL--TVLNSMHSHFILADNG-----TTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLDSRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDIL--AF--------GHKYSEEGG--LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGAN-------ASAPDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDP--EINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILRLQ--------DQP--FRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYG------EVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL---KLFITDDELKKVHDFEEQCIEEYFREKDDRF----NSSNDERIRVTSERVENMSMRLEEVN---EREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAY--IVRQSS------FNSQEGNTFKLQESIDPAGEET 1184
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Celegans
Match: gtl-2 (Gon-Two Like (TRP subfamily) [Source:UniProtKB/TrEMBL;Acc:Q20766]) HSP 1 Score: 207.608 bits (527), Expect = 7.458e-54 Identity = 201/801 (25.09%), Postives = 359/801 (44.82%), Query Frame = 1
Query: 280 YINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGP---------RESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVG---YFRQALENKISQKQGDRVGIPVVLLIVEGG-------HDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDG--VAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELL-ITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELY-----ETCPKSTNFRKTF------------------LRLIGRPFS--------KGLNDVKELLSKMIGFYE---------YPCSENDSIKHPFQELFLWA----------VLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENL------AVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTW------RAGFNINFFSCILC---IIFPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISSKLRRFYVAPQTK 2421
+I F+ EC F+ K+ + +C CG +H + +++W+ + + T +FG I F G ++ +VR+SY + D++ L+ W + A L I+V GG +F++ + +F +G++KAA TT A IIT GL+ G+ + A+ ++ + +M+ I +GIAPWG +K + L + V+Y+V + LN H++++ D+G T + G + RQ LEN I+ + +PVV ++EGG HD +K + +VC+G+G+A+DII A R I SDG A + E +N++K E D E+ + K E +I+++LL I + + ED+DF IL +++++ +L D QL+L L+WNRVD+ K +FS S+D + D++ +V F+E LEN ++++FL+ N L+ LY + N+ + F +L+G F KG D + +++ F+ + +D I +E F +A VL + A+ W ++++ L+A R+YK + + D +E K F+N A++L+++C+ D + L+ + +WG +CL LA + F+++ CQ + W R+G N+ + ++C I+F K ++ + E P E TS +S R+ P+ +
Sbjct: 88 WIENTFEKRECIRFAALPKDPE----RCGCGRPLSAHTPASTFFSTLPVHLLEKEQQTWTIANNTQTSTTDAFGTIVFQGG--AHAHKAQYVRLSYDSEPLDVMYLMEKVWGLEAPRLVITVHGGMSNFELEERLGRLFRKGMLKAAQTTGAWIITSGLDSGVVRHVAKALD--EAGISARMRSQ--IVTIGIAPWGVIKRKERL-IRQNEHVYYDVHSLSVNANVGILNDRHSYFLLADNG-----TVGRFGADLHLRQNLENHIATFGCNGRKVPVVCTLLEGGISSINAIHDYVT-----MKPDIPAIVCDGSGRAADIISFAAR----------YINSDGTFAAEVGEKLRNLIKMVFPETDQEEMFR-----KITECVIRDDLLRIFRYGQEEEEDVDFVILSTVLQKQNLPPD-------EQLALTLSWNRVDLAKSCLFSNGRKWSSDVLEKAMNDALYWDRVDFVECLLENGVSMKNFLSINRLENLYNMDDINSAHSVRNWMENFDSMDPHTYLTIPMIGQVVEKLMGNAFQLYYTSRSFKGKYDRYKRINQSSYFHRKRKIVQKELFKKKSDDQINDNEEEDFSFAYPFNDLLIWAVLTSRHGMAECMWVHGEDAMAKCLLAIRLYKATAKIA---EDEYLDVEEAKRLFDNAVKCREDAIELLDQCYRADHDRTLRLLRMELPHWGNNNCLSLAVLANTKTFLAHPCCQILLAELWHGSLKVRSGSNVRVLTALICPPAILFMAYKPKHSKTARLLSEETPEQLPYPRES--ITSTTSNRYRYSKGPEEQ 840 HSP 2 Score: 85.5001 bits (210), Expect = 2.734e-16 Identity = 93/361 (25.76%), Postives = 169/361 (46.81%), Query Frame = 1
Query: 2386 KLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWT--FNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQ-RDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNSKLHI-----DKPMAFKHDTLNIFSNIK 3444
+ R FY +P TKF F+ F+ + ++L ++ + +E + IY V + ++ ++ S RI ++K ++ +N W L + L G + W + + S FY+KI L+ H LGP I M +K++ + ++L+ L+++GV QA P +D+ W+ + NI PY+ ++G + G T + C F+ P+L ++++ NILLLN+LIA + I D S IW + Y ++EY+D P LP PFS F ++Y + + Y R ++K+F ++H+ KL + + F+ D ++ + I+
Sbjct: 888 RFRAFYSSPITKFWSWCIAFLIFLTTQTCILLLETS-LKPSKYEWITFIYTVTLSVEHIRKLMTSEGSRINEKVKVFYAKWYNIWTSAA------------LLFFLVGYGFRLVPMYRHSWGRVLLSFSNVLFYMKIFEYLSVHPLLGPYIQMAAKMVWSMCYICVLLLVPLMAFGVNRQALTEPNVKDWHWLLVRNIFYKPYFMLYGEVYAGEI--------DTCGDEGIRCFPGYFIPPLLMVIFLLVANILLLNLLIAIFNNIYNDSIEKSKEIWLFQRYQQLMEYHDSPFLPPPFSIFAHVYHFIDYLYNLRR----PDTKRFR-SEHSIKLSVTEDEMKRIQDFEEDCIDTLTRIR 1222
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971]) HSP 1 Score: 178.718 bits (452), Expect = 7.860e-45 Identity = 166/605 (27.44%), Postives = 270/605 (44.63%), Query Frame = 1
Query: 169 NEDYTVTIRQARCKINESCRESNVHFAENDEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIP-------------------------------------YGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQ---GDRVGIPVVLLIVEGGHDIFIEASRRVK--EKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKN---VLKRKLIEQDISELHQ-VDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKG----LNDVKELLSKMIGFYEYPCS 1833
NED + T A+ + + + F E++ + N++ F EC F + +++ KC CG + +H+ IP G E WS L T +FG++EF G + +VRV++ + I+ L + W+I+ L I+V GGT +F + K +F +GL+KAA TT A IIT G + G+ + A++ +QS N I C+GIAPWG +K R + +TV Y S+ K + LN H++++ D+G + + + R+ LE ISQKQ G +PVV +++EGG V +V +VVC+G+G+A+D++ A H+ + DG +LP+ + +L + H+ + E C + KN L I + D+D AIL +L+K + + QL+L L WNRVDI + +F+ + +++I +V F+ L LE N+Q FLT + L ELY T N +R + R +G L D+ ++ K++G Y CS
Sbjct: 147 NEDVSATANSAQLVLPTPLF-NQMRFTESNMSLNRHNWVRETFTRRECSRFIASSRDL----HKCGCGRTRDAHR--NIPELTSEFLRQKRSVAALEQQRSISNVNDDINTQNMYTKRGANEKWSLRKHTVSLATNAFGQVEFQGG--PHPYKAQYVRVNFDTEPAYIMSLFEHVWQISPPRLIITVHGGTSNFDLQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVAAALEGAQS------AQRNKIVCIGIAPWGLLKKREDF-IGQDKTVPYYPSS--SKGRFTGLNNRHSYFLLVDNGTVGRYGAEVI--LRKRLEMYISQKQKIFGGTRSVPVVCVVLEGGSCTIRSVLDYVTNVPRVPVVVCDGSGRAADLLAFA----------HQNVTEDG--LLPDDIRRQVLLLVETTFGCSEAAAHRLLHELTVCAQH--KNLLTIFRLGEQGEHDVDHAILTALLKGQN-------LSAADQLALALAWNRVDIARSDVFAMGHEWPQAALHNAMMEALIHDRVDFVRLLLEQGINMQKFLTISRLDELYNTDKGPPNTLFYIVRDVVR-VRQGYRFKLPDIGLVIEKLMG-NSYQCS 708 HSP 2 Score: 77.411 bits (189), Expect = 6.975e-14 Identity = 45/153 (29.41%), Postives = 74/153 (48.37%), Query Frame = 1
Query: 1849 KHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFEN---LAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINFFS---CILCIIFPFLI 2289
++P+ EL +WAVL ++Q A W +E++ ALVA R+YK + D E E K Y E L+++L++ C+ +D L+ + NW +CL LA + F+++ CQ + W G + S +L +I P I
Sbjct: 849 RYPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGLRMRTHSNIKVVLGLICPPFI 1001
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971]) HSP 1 Score: 178.718 bits (452), Expect = 8.248e-45 Identity = 166/605 (27.44%), Postives = 270/605 (44.63%), Query Frame = 1
Query: 169 NEDYTVTIRQARCKINESCRESNVHFAENDEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIP-------------------------------------YGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQ---GDRVGIPVVLLIVEGGHDIFIEASRRVK--EKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKN---VLKRKLIEQDISELHQ-VDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKG----LNDVKELLSKMIGFYEYPCS 1833
NED + T A+ + + + F E++ + N++ F EC F + +++ KC CG + +H+ IP G E WS L T +FG++EF G + +VRV++ + I+ L + W+I+ L I+V GGT +F + K +F +GL+KAA TT A IIT G + G+ + A++ +QS N I C+GIAPWG +K R + +TV Y S+ K + LN H++++ D+G + + + R+ LE ISQKQ G +PVV +++EGG V +V +VVC+G+G+A+D++ A H+ + DG +LP+ + +L + H+ + E C + KN L I + D+D AIL +L+K + + QL+L L WNRVDI + +F+ + +++I +V F+ L LE N+Q FLT + L ELY T N +R + R +G L D+ ++ K++G Y CS
Sbjct: 187 NEDVSATANSAQLVLPTPLF-NQMRFTESNMSLNRHNWVRETFTRRECSRFIASSRDL----HKCGCGRTRDAHR--NIPELTSEFLRQKRSVAALEQQRSISNVNDDINTQNMYTKRGANEKWSLRKHTVSLATNAFGQVEFQGG--PHPYKAQYVRVNFDTEPAYIMSLFEHVWQISPPRLIITVHGGTSNFDLQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVAAALEGAQS------AQRNKIVCIGIAPWGLLKKREDF-IGQDKTVPYYPSS--SKGRFTGLNNRHSYFLLVDNGTVGRYGAEVI--LRKRLEMYISQKQKIFGGTRSVPVVCVVLEGGSCTIRSVLDYVTNVPRVPVVVCDGSGRAADLLAFA----------HQNVTEDG--LLPDDIRRQVLLLVETTFGCSEAAAHRLLHELTVCAQH--KNLLTIFRLGEQGEHDVDHAILTALLKGQN-------LSAADQLALALAWNRVDIARSDVFAMGHEWPQAALHNAMMEALIHDRVDFVRLLLEQGINMQKFLTISRLDELYNTDKGPPNTLFYIVRDVVR-VRQGYRFKLPDIGLVIEKLMG-NSYQCS 748 HSP 2 Score: 77.411 bits (189), Expect = 7.305e-14 Identity = 45/153 (29.41%), Postives = 74/153 (48.37%), Query Frame = 1
Query: 1849 KHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFEN---LAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINFFS---CILCIIFPFLI 2289
++P+ EL +WAVL ++Q A W +E++ ALVA R+YK + D E E K Y E L+++L++ C+ +D L+ + NW +CL LA + F+++ CQ + W G + S +L +I P I
Sbjct: 889 RYPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGLRMRTHSNIKVVLGLICPPFI 1041
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971]) HSP 1 Score: 178.333 bits (451), Expect = 1.124e-44 Identity = 167/605 (27.60%), Postives = 271/605 (44.79%), Query Frame = 1
Query: 169 NEDYTVTIRQARCKINESCRESNVHFAENDEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIP-------------------------------------YGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQ---GDRVGIPVVLLIVEGGHDIFIEASRRVK--EKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKN---VLKRKLIEQDISELHQ-VDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKG----LNDVKELLSKMIGFYEYPCS 1833
NED + T A+ + + + F E++ + N++ F EC F + +++ KC CG + +H+ IP G E WS L T +FG++EF G + +VRV++ + I+ L + W+I+ L I+V GGT +F + K +F +GL+KAA TT A IIT G + G+ + A++ +QS N I C+GIAPWG +K R + +TV Y S+ K + LN H++++ D+G + + + R+ LE ISQKQ G +PVV +++EGG V +V +VVC+G+G+A+D++ A H+ + DG +LP+ + +L + H+ + E C + KN L I + D+D AIL +L+K +L + QL+L L WNRVDI + +F+ + +++I +V F+ L LE N+Q FLT + L ELY T N +R + R +G L D+ ++ K++G Y CS
Sbjct: 248 NEDVSATANSAQLVLPTPLF-NQMRFTESNMSLNRHNWVRETFTRRECSRFIASSRDL----HKCGCGRTRDAHR--NIPELTSEFLRQKRSVAALEQQRSISNVNDDINTQNMYTKRGANEKWSLRKHTVSLATNAFGQVEFQGG--PHPYKAQYVRVNFDTEPAYIMSLFEHVWQISPPRLIITVHGGTSNFDLQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVAAALEGAQS------AQRNKIVCIGIAPWGLLKKREDF-IGQDKTVPYYPSS--SKGRFTGLNNRHSYFLLVDNGTVGRYGAEVI--LRKRLEMYISQKQKIFGGTRSVPVVCVVLEGGSCTIRSVLDYVTNVPRVPVVVCDGSGRAADLLAFA----------HQNVTEDG--LLPDDIRRQVLLLVETTFGCSEAAAHRLLHELTVCAQH--KNLLTIFRLGEQGEHDVDHAILTALLKGQNLS-------AADQLALALAWNRVDIARSDVFAMGHEWPQAALHNAMMEALIHDRVDFVRLLLEQGINMQKFLTISRLDELYNTDKGPPNTLFYIVRDVVR-VRQGYRFKLPDIGLVIEKLMG-NSYQCS 809 HSP 2 Score: 77.411 bits (189), Expect = 7.105e-14 Identity = 45/153 (29.41%), Postives = 74/153 (48.37%), Query Frame = 1
Query: 1849 KHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFEN---LAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINFFS---CILCIIFPFLI 2289
++P+ EL +WAVL ++Q A W +E++ ALVA R+YK + D E E K Y E L+++L++ C+ +D L+ + NW +CL LA + F+++ CQ + W G + S +L +I P I
Sbjct: 950 RYPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGLRMRTHSNIKVVLGLICPPFI 1102
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Celegans
Match: gtl-1 (GTL-1; Gon-Two Like (TRP subfamily) [Source:UniProtKB/TrEMBL;Acc:G5ECM4]) HSP 1 Score: 173.326 bits (438), Expect = 3.263e-43 Identity = 153/568 (26.94%), Postives = 257/568 (45.25%), Query Frame = 1
Query: 265 MQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKE---------------------------------NKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHN--NFISCLGIAPWGYVKNRNILEFAKGRTVHY--NVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQKQGDRVGIPVVLLIVEGG-------HDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVL---KRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDI--KSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKGLNDVKELLSKMIG 1812
++ +N+I + K +C YF + + + +C CG+ + H E N++ P WS E++PT ++G I F G + + R+S+ DIV L+ WK+ L I++ GG F + K F +G++K A +T+A IIT GL++G+ +++ S L+D H N + +GIA WG +K R+ K TV Y NV N + LN NH++++F D+G T + G R+ LE ++Q R IP+V +++EGG HD R + ++VC+G+G+A+DI+ A H+ + +G L ++ +N L R++ D ++ IK I + N+ L+T+F + S EDLD I+ L+K +L QL L L WNR DI + +IF+ + + + +++ ++ F+ L LEN ++Q FLT L+ LY T N +T L L+ L +V L+ ++G
Sbjct: 100 LKGKNWIECRLKMRQCSYFVPSQR----FSERCGCGKERSKHTEEVLERSQNKNHPLNHLTLPGIHEVDTTDADADDNEVNLTPGR-WSIQSHTEIVPTDAYGNIVFEG----TAHHAQYARISFDSDPRDIVHLMMKVWKLKPPKLIITINGGLTKFDLQPKLARTFRKGIMKIAKSTDAWIITSGLDEGV-------VKHLDSALHDHGNHTSKNHVVAIGIASWGMLKQRSRF-VGKDSTVTYATNVFNNTRLKE---LNDNHSYFLFSDNG-----TVNRYGAEIIMRKRLEAYLAQGDKKRSAIPLVCVVLEGGAFTIKMVHDYVTTIPR-----IPVIVCDGSGRAADILAFA----------HQAVSQNG--FLSDNIRNQLVNIVRRIFGYDPKTAQKL---IKQIVECSTNKSLMTIFRLGESSREDLDHVIMSCLLKGQNL-------SPPEQLQLALAWNRADIARTEIFANGTEWTTQDLHNAMIEALSNDRIDFVHLLLENGVSMQKFLTYGRLEHLYNTDKGPQNTLRTNL-LVDSKHHIKLVEVGRLVENLMG 614 HSP 2 Score: 84.3445 bits (207), Expect = 6.141e-16 Identity = 46/163 (28.22%), Postives = 83/163 (50.92%), Query Frame = 1
Query: 1843 SIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDR---SETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGF------NINFFSCILCIIFPFLISKRTE 2304
+ ++P+ +L +WAVL ++QK AK W +E + ALVA+R+Y +T+ T S+ + + F LAV+++E C ++ L+ + NWG +CL LA+ + KF+++ CQ + W+ G N +C+ FL+ +T+
Sbjct: 712 TFRYPYSDLMIWAVLTKRQKMAKLMWTHGEEGMAKALVASRLYVSLAKTASLATGEIGMSQDFTEFSDEFSELAVEVLEYCTKHGRDQTLRLLTCELANWGDETCLSLAANNGHRKFLAHPCCQMLLSDLWQGGLLMKNNQNSKVLTCLAAPPLIFLLGFKTK 874 HSP 3 Score: 56.9954 bits (136), Expect = 1.124e-7 Identity = 45/198 (22.73%), Postives = 98/198 (49.49%), Query Frame = 1
Query: 2782 LKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFG------VLNLGNTVYFTWCNASTNYEVSN----ECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSN 3345
LK++ L+ + LGP I +++++I ++ ++ I L ++G+ Q+ YP D+ WI + NI PY+ ++G + G+ ++ T + + + N C ++ P+ +++ N+LL+N+++A +YI + ++ I+ + Y ++EY P LP PF+ ++ + R + N
Sbjct: 1193 LKLVDYLSVQQGLGPYINIVAEMIPTMIPLCVLVFITLYAFGLLRQSITYPYEDWHWILVRNIFLQPYFMLYGEVYAAEIDTCGDEIWQTHEDENIPISMLNVTHETCVPGYWIAPVGLTVFMLATNVLLMNVMVAGCTYIFEKHIQSTREIFLFERYGQVMEYESTPWLPPPFTIIYHVIWLFKLIKSSSRMFERKN 1390
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339082) HSP 1 Score: 291.967 bits (746), Expect = 6.569e-80 Identity = 329/1257 (26.17%), Postives = 547/1257 (43.52%), Query Frame = 1
Query: 268 QYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPY----GPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYV-KNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQ---KQGDRVGIPVVLLIVEGGHDIFIEASRRVKE--KVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSH-----EDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKG----LNDVKELLSKMIG-------------------------------FYEYP-----------------CSENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNY---FENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGF----NINFFSCILCIIFPFLIS----KRTEFTKDFKTCQSESFPDFNEDNCRTSISS-------------------------------------KLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNE-CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNS-KLHIDKPMAFKHDTLNIFSNIKSDSDLNKLIKYFENYSQKFVIKNIAIEKQKS---IKSGISRMEIRSKSI--FKELENIQTK-LNKIQIKNVKKVQEGS 3660
Q R++I F+ EC F K+ ++KC CG+ + +H+ IP P + W PT ++G IEF G + +VR+S+ + + +V L +W + L I+V GG +F + K K +GL+KAA TT A I T G N G+T +GDA+ L + + + +GIAPWG V +N +L + H S + + LN H +++ D+G T+ K G R+ LE IS PVV L++EGG + V + V +VVC+G+G+A+D++ AF HK + ES ++ L + + L Q ++ + + +N+ LITVF I+ ++LD IL +L K L QLSL LTWNRVDI + +IF N + ++ ++ F++L LEN +++ FLT L+ELY T N LR + KG L+D+ +++K++G Y+Y SE + PF EL +WAVL ++Q+ A W +E+L +LV+ ++YK + D +E E ++Y FE+ KL++ + D E A L+ + +W SCL LA + +++ Q + W G N N F IL + PF I K E + + E + N DN + S K FY AP TKF S ++ F+I FS+ VL M++M E + Y+ + +K EI S I + W +N WN D I+ ++ + R++ + + IY + +YL+IL +L +K LGP + MM K++K ++ F ++ + L+S+GV+ QA YP + +W + + PY+ ++G + G+ + + S C +++ PI + Y++I NILL+N+LIA + I +++ S +W + +++++EY KP+LP PF + Y +L +C +K +K E+ + N KL ++K DL +L + E + F + I Q + +K+ R+E S+ I + ENIQT + I+ + ++K++E S
Sbjct: 11 QPRSWIETNFQKRECIKFIPCPKD----DTKCCCGQAQITHQ--TIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGG--AHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL------LLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCH---SISSPRSKLAVLNNRHAYFLLVDNG-----TQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLL--AF--------VHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQHL-------SPPEQLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTN-FKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMP-RWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSV-WAWNMWNPCDGAAIILFVIGLAFRFRENTMDI----------GRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGD------IDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKYCVRK--------AKGLEVQRDNGLKLFLEK------------------DDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVETMSQKIEDINQKENIQTATVQNIEFR-LRKMEESS 1182
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339075) HSP 1 Score: 281.952 bits (720), Expect = 7.674e-78 Identity = 304/1168 (26.03%), Postives = 505/1168 (43.24%), Query Frame = 1
Query: 238 VHFAENDEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPY----GPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYV-KNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQ---KQGDRVGIPVVLLIVEGGHDIFIEASRRVKE--KVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSH-----EDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKG----LNDVKELLSKMIG-------------------------------FYEYP-----------------CSENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNY---FENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGF----NINFFSCILCIIFPFLIS----KRTEFTKDFKTCQSESFPDFNEDN--------------------------------CRTSISSKLRRF------------------------YVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNE-CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGR 3327
++F N Q R++I F+ EC F K+ ++KC CG+ + +H+ IP P + W PT ++G IEF G + +VR+S+ + + +V L +W + L I+V GG +F + K K +GL+KAA TT A I T G N G+T +GDA+ L + + + +GIAPWG V +N +L + H S + + LN H +++ D+G T+ K G R+ LE IS PVV L++EGG + V + V +VVC+G+G+A+D++ AF HK + ES ++ L + + L Q ++ + + +N+ LITVF I+ ++LD IL +L K L QLSL LTWNRVDI + +IF N + ++ ++ F++L LEN +++ FLT L+ELY T N LR + KG L+D+ +++K++G Y+Y SE + PF EL +WAVL ++Q+ A W +E+L +LV+ ++YK + D +E E ++Y FE+ KL++ + D E A L+ + +W SCL LA + +++ Q + W G N N F IL + PF I K E + + E + N DN S +++ R F Y AP TKF S ++ F+I FS+ VL M++M E + Y+ + +K EI S I + W +N WN D I+ ++ + R++ + + IY + +YL+IL +L +K LGP + MM K++K ++ F ++ + L+S+GV+ QA YP + +W + + PY+ ++G + G+ + + S C +++ PI + Y++I NILL+N+LIA + I +++ S +W + +++++EY KP+LP PF + Y +L +C +K +
Sbjct: 1 MYFETNWVFHQPRSWIETNFQKRECIKFIPCPKD----DTKCCCGQAQITHQ--TIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGG--AHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL------LLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCH---SISSPRSKLAVLNNRHAYFLLVDNG-----TQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLL--AF--------VHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQHL-------SPPEQLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTN-FKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMP-RWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSV-WAWNMWNPCDGAAIILFVIGLAFRFRENTMDI----------GRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGD------IDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKYCVRKAK 1110
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339074) HSP 1 Score: 284.263 bits (726), Expect = 1.710e-77 Identity = 332/1278 (25.98%), Postives = 552/1278 (43.19%), Query Frame = 1
Query: 262 KMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPY----GPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVH-YNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQ---KQGDRVGIPVVLLIVEGGHDIFIEASRRVKE--KVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSH-----EDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKG----LNDVKELLSKMIG-------------------------------FYEYP-----------------CSENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNY---FENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGF----NINFFSCILCIIFPFLIS----KRTEFTKDFKTCQSESFPDFNEDN--------------------------------CRTSISSKLRRF------------------------YVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNE-CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNS-KLHIDKPMAFKHDTLNIFSNIKSDSDLNKLIKYFENYSQKFVIKNIAIEKQKS---IKSGISRMEIRSKSI--FKELENIQTK-LNKIQIKNVKKVQEGS 3660
K Q R++I F+ EC F K+ ++KC CG+ + +H+ IP P + W PT ++G IEF G + +VR+S+ + + +V L +W + L I+V GG +F + K K +GL+KAA TT A I T G N G+T +GDA+ L + + + +GIAPWG V+ RN R V +++S+ K LN H +++ D+G T+ K G R+ LE IS PVV L++EGG + V + V +VVC+G+G+A+D++ AF HK + ES ++ L + + L Q ++ + + +N+ LITVF I+ ++LD IL +L K L QLSL LTWNRVDI + +IF N + ++ ++ F++L LEN +++ FLT L+ELY T N LR + KG L+D+ +++K++G Y+Y SE + PF EL +WAVL ++Q+ A W +E+L +LV+ ++YK + D +E E ++Y FE+ KL++ + D E A L+ + +W SCL LA + +++ Q + W G N N F IL + PF I K E + + E + N DN S +++ R F Y AP TKF S ++ F+I FS+ VL M++M E + Y+ + +K EI S I + W +N WN D I+ ++ + R++ + + IY + +YL+IL +L +K LGP + MM K++K ++ F ++ + L+S+GV+ QA YP + +W + + PY+ ++G + G+ + + S C +++ PI + Y++I NILL+N+LIA + I +++ S +W + +++++EY KP+LP PF + Y +L +C +K +K E+ + N KL ++K DL +L + E + F + I Q + +K+ R+E S+ I + ENIQT + I+ + ++K++E S
Sbjct: 27 KHQPRSWIETNFQKRECIKFIPCPKD----DTKCCCGQAQITHQ--TIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGG--AHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL------LLEGQQRTGRVVSIGIAPWGIVE-RNHELLGHNREVPCHSISSPRSKL--AVLNNRHAYFLLVDNG-----TQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLL--AF--------VHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQHL-------SPPEQLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTN-FKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMP-RWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSV-WAWNMWNPCDGAAIILFVIGLAFRFRENTMDI----------GRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGD------IDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKYCVRK--------AKGLEVQRDNGLKLFLEK------------------DDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVETMSQKIEDINQKENIQTATVQNIEFR-LRKMEESS 1219
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339076) HSP 1 Score: 283.878 bits (725), Expect = 2.756e-77 Identity = 329/1276 (25.78%), Postives = 549/1276 (43.03%), Query Frame = 1
Query: 268 QYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPY----GPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYV-KNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQ---KQGDRVGIPVVLLIVEGGHDIFIEASRRVKE--KVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSH-----EDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKG----LNDVKELLSKMIG-------------------------------FYEYP-----------------CSENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNY---FENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGF----NINFFSCILCIIFPFLIS----KRTEFTKDFKTCQSESFPDFNEDN--------------------------------CRTSISSKLRRF------------------------YVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNE-CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNS-KLHIDKPMAFKHDTLNIFSNIKSDSDLNKLIKYFENYSQKFVIKNIAIEKQKS---IKSGISRMEIRSKSI--FKELENIQTK-LNKIQIKNVKKVQEGS 3660
Q R++I F+ EC F K+ ++KC CG+ + +H+ IP P + W PT ++G IEF G + +VR+S+ + + +V L +W + L I+V GG +F + K K +GL+KAA TT A I T G N G+T +GDA+ L + + + +GIAPWG V +N +L + H S + + LN H +++ D+G T+ K G R+ LE IS PVV L++EGG + V + V +VVC+G+G+A+D++ AF HK + ES ++ L + + L Q ++ + + +N+ LITVF I+ ++LD IL +L K L QLSL LTWNRVDI + +IF N + ++ ++ F++L LEN +++ FLT L+ELY T N LR + KG L+D+ +++K++G Y+Y SE + PF EL +WAVL ++Q+ A W +E+L +LV+ ++YK + D +E E ++Y FE+ KL++ + D E A L+ + +W SCL LA + +++ Q + W G N N F IL + PF I K E + + E + N DN S +++ R F Y AP TKF S ++ F+I FS+ VL M++M E + Y+ + +K EI S I + W +N WN D I+ ++ + R++ + + IY + +YL+IL +L +K LGP + MM K++K ++ F ++ + L+S+GV+ QA YP + +W + + PY+ ++G + G+ + + S C +++ PI + Y++I NILL+N+LIA + I +++ S +W + +++++EY KP+LP PF + Y +L +C +K +K E+ + N KL ++K DL +L + E + F + I Q + +K+ R+E S+ I + ENIQT + I+ + ++K++E S
Sbjct: 11 QPRSWIETNFQKRECIKFIPCPKD----DTKCCCGQAQITHQ--TIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGG--AHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL------LLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCH---SISSPRSKLAVLNNRHAYFLLVDNG-----TQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLL--AF--------VHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQHL-------SPPEQLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTN-FKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMP-RWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSV-WAWNMWNPCDGAAIILFVIGLAFRFRENTMDI----------GRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGD------IDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKYCVRK--------AKGLEVQRDNGLKLFLEK------------------DDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVETMSQKIEDINQKENIQTATVQNIEFR-LRKMEESS 1201
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339079) HSP 1 Score: 282.722 bits (722), Expect = 5.731e-77 Identity = 331/1276 (25.94%), Postives = 551/1276 (43.18%), Query Frame = 1
Query: 268 QYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPY----GPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVH-YNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQ---KQGDRVGIPVVLLIVEGGHDIFIEASRRVKE--KVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSH-----EDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKG----LNDVKELLSKMIG-------------------------------FYEYP-----------------CSENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNY---FENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGF----NINFFSCILCIIFPFLIS----KRTEFTKDFKTCQSESFPDFNEDN--------------------------------CRTSISSKLRRF------------------------YVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNE-CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNS-KLHIDKPMAFKHDTLNIFSNIKSDSDLNKLIKYFENYSQKFVIKNIAIEKQKS---IKSGISRMEIRSKSI--FKELENIQTK-LNKIQIKNVKKVQEGS 3660
Q R++I F+ EC F K+ ++KC CG+ + +H+ IP P + W PT ++G IEF G + +VR+S+ + + +V L +W + L I+V GG +F + K K +GL+KAA TT A I T G N G+T +GDA+ L + + + +GIAPWG V+ RN R V +++S+ K LN H +++ D+G T+ K G R+ LE IS PVV L++EGG + V + V +VVC+G+G+A+D++ AF HK + ES ++ L + + L Q ++ + + +N+ LITVF I+ ++LD IL +L K L QLSL LTWNRVDI + +IF N + ++ ++ F++L LEN +++ FLT L+ELY T N LR + KG L+D+ +++K++G Y+Y SE + PF EL +WAVL ++Q+ A W +E+L +LV+ ++YK + D +E E ++Y FE+ KL++ + D E A L+ + +W SCL LA + +++ Q + W G N N F IL + PF I K E + + E + N DN S +++ R F Y AP TKF S ++ F+I FS+ VL M++M E + Y+ + +K EI S I + W +N WN D I+ ++ + R++ + + IY + +YL+IL +L +K LGP + MM K++K ++ F ++ + L+S+GV+ QA YP + +W + + PY+ ++G + G+ + + S C +++ PI + Y++I NILL+N+LIA + I +++ S +W + +++++EY KP+LP PF + Y +L +C +K +K E+ + N KL ++K DL +L + E + F + I Q + +K+ R+E S+ I + ENIQT + I+ + ++K++E S
Sbjct: 18 QPRSWIETNFQKRECIKFIPCPKD----DTKCCCGQAQITHQ--TIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGG--AHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL------LLEGQQRTGRVVSIGIAPWGIVE-RNHELLGHNREVPCHSISSPRSKL--AVLNNRHAYFLLVDNG-----TQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLL--AF--------VHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQHL-------SPPEQLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTN-FKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMP-RWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSV-WAWNMWNPCDGAAIILFVIGLAFRFRENTMDI----------GRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGD------IDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLKYCVRK--------AKGLEVQRDNGLKLFLEK------------------DDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVETMSQKIEDINQKENIQTATVQNIEFR-LRKMEESS 1208
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Zebrafish
Match: trpm2 (transient receptor potential cation channel, subfamily M, member 2 [Source:NCBI gene;Acc:799412]) HSP 1 Score: 281.952 bits (720), Expect = 6.542e-77 Identity = 286/1101 (25.98%), Postives = 509/1101 (46.23%), Query Frame = 1
Query: 277 NYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGPR----ESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQ-KQGDR---VGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQD---ISELHQVDEAIKCIEDIIKNELLITVFDIKSHE--DLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLT-ANILKELYETCPKSTNFRKTFLRLIGRPFSKG-----------LNDVKELLSKMIGFY---------------------------EYPCS----ENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIY-KYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN--FFSCILCII-FPFL------------ISKRTEFTKDFKTCQSESFPDFNEDNCRTSI--------------SSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRD-FSWIALSNILDYPYYTMFG--VLNLGNTVY-FTWCNASTNYEVSNECP----ENNFLIP-----ILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPF 3273
++I K EC ++ D + C CG K H + I P E W + + PT +FG I F G K +VRVS +++ L+ +WK+ + L ISV GG +F + K+ F +GLIK A TT A I+T G + G+ +G A+ + Y I +G+APWG + NR+ L +GR Y +E + + L+ NHTH++ DDG T+ G R LE IS+ G+R V IPVV ++++GG + VV EG+G+ +D+I + S V+ + + N L ++ Q+ +EL Q+ E K I+DI++ L+TVF I + D+D AIL +L+K + ++ QL L + WNRVDI + +IF+ + ++ + + +++ K +F+ L LEN +++FL L ELY P RK R+ G +G L+ V E + ++G + + PCS D++ P ++LFLWAV+ ++ A+ W +C + + AL A++I K Q + D++ + + N++E A+ + ECH D + A L+ + + +WG +CL LA ++ D F+++ Q + W +++ + +LC+I FP + I ++ E T+ K F ++ + + SS+L F +PQ KF + ++ F+ F+ V++ + + E++ ++L ++ ++ +++ + R + + WN +D++ IV I ++ R Q + Y KV++ I+ F L+++ + + + LGPKI ++ +++ +L F ++ I++++YGV Q + +WI + + PY T+FG N+ NT++ + C+ + + + +CP +N + P ++ Y++ NILLLN+LIA +Y Q++ N+ IWK+ Y LI EY+ +P LP PF
Sbjct: 38 SWIKENIKKKECCFYVE-----DGREGICKCGYPKVQHCDEAI--KPEDYMGEQWDKHRHVRETPTDAFGDISFGG---LGQKTGKYVRVSSDTSCENLYQLMTEQWKLRSPNLLISVTGGAKNFYIKTHLKDKFRRGLIKVAQTTGAWILTGGTHAGVMKHVGMAV---RDYTLSSGSMEGQIVVIGVAPWGVIHNRSTLIHPEGRFPAYYSLDEQGQGRLSCLDINHTHFLLVDDG-----TQGHYGVEIELRARLEKLISKLSLGNRESGVTIPVVCVVLDGGPGTLNTIYNSMLNHTPCVVLEGSGRLADVIAH--------------VASVPVSKVTMALINRLLKRFFMQEYKNFTEL-QIIEWTKKIQDILRMPHLLTVFRIDEDKNYDVDVAILQALLKASRSDEHAGRHCWERQLELAVAWNRVDIAESEIFTEESQWTSSDLHPAMFSALVGDKPEFVRLLLENGVCVREFLEREETLCELYSHLPSCFFLRKLAKRVQGGKMRRGQEPLPGSRKVCLSHVSEEVRHLLGSFTQPLYIASRYKPTKDDVRLKVPSKGALDLPCSGEEWSADTVWDPGRDLFLWAVVQNNRELAEIGWEQCRDCIAAALAASKILRKLAQESGEDDSEEATEMLELANHYEKQAIGVFSECHSWDAQRAQKLLIRISPSWGRSTCLWLALEAHDKSFIAHSGVQALLTQIWCGELSVDNPHWKVLLCMIFFPLIYTGFLTFRRDEDIQRQAERTEQQKLAMESVFAGQSDGKIKRHLRGFSQKSELKPLNCSSRLMSFLKSPQVKFYWNIASYFGFLWLFAVVLMIDFQ-TSPSWRELLLYVWLTSLVCEEIRQLYHDFDGSGFRRKAKMYIKDLWNILDVLSIVLFIAGLICRLQASDTVFYIGKVIL------CIDFII--FCLRLMAIFSISRTLGPKIIIVRRMMLDLFFFMFLLSIWVVAYGVAKQGILIENEERLNWIIRGAVYE-PYITIFGNFPTNIDNTLFDISSCSVNASDPLKPKCPMLNADNTPVFPEWLTIMMLCVYLLFANILLLNLLIAIFNYTFQEVQDNTDTIWKFQRYELIKEYHSRPALPPPF 1095
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Zebrafish
Match: trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:ZFIN;Acc:ZDB-GENE-060503-736]) HSP 1 Score: 244.973 bits (624), Expect = 1.328e-65 Identity = 263/1042 (25.24%), Postives = 472/1042 (45.30%), Query Frame = 1
Query: 469 FGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQ-YSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKIS-QKQG----DRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXX---XXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKST-NFRKTFL--------------RLIGRP--------FSKGLNDVKELLSKMI-----GFYEYPCSENDSI------------KHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNY-FENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINFFSCILCIIF---PFLISKRTEFTKDFKTCQSESFPDFNEDNCRTS-------------------------------ISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQ---LTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRD-FSWIALSNILDYPYYTMFGVLNLG--NTVYFTWCNASTNYE-----VSNECPE--NNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVL 3303
G I+FTG T K FVRV+ +I ++ +W + L ++++GG ++ ++ +GL+KAA +T A I+T GL GIT +G A++ +S + K++ + +GIAPW ++NR++L AK + ++ SL+ NH+H+I D+ + G R + IS Q+ G + IPV+ L+V G I + + ++ + ++ G+G +DI+ M R C +++ + P+ + ++ K I+ I+ + L+TV D + +LD IL +L+K C S +L L + WNRVDI K +IFSGD+ S + + ++++ K F+ LF++N NI+ FLT L+ELY C S N T L R+ G P F ++V ++L + GFY+ + + ++ +HP+++LFLWA+L +Q+ A +FW E++ ALV +I K + +E+ + KN +E A+ L EC+ ++ A L+ +K W + L +A+ + F ++ Q + W + L + F P + + +F + + + E P D+ T + + RF+ AP T F + + +F+I FSYV+L + + EI+ ++ ++L++ + F + D + + ++WNK DM+ I +V + R ++ + +T+ +L F L+++ + A HK+LGPKI ++ ++IK++ F + ++L++YGVT+QA +P W+ L PY +FG + L + N +T+ + CP N+L+ +L Y+++ N+LLLN+LIA SY Q + N+ + WK+ Y+LI+EY+ +P L PF +I Q L
Sbjct: 17 LGDIDFTGVSRTRGK---FVRVTSSTDPAEIYQILTKQWGLAPPHLVVALMGGDEVAQLKPWLRDTLRKGLVKAAQSTGAWILTSGLRFGITKNLGQAVRDHSLASTSPKVR----VVAIGIAPWNMIQNRDLLLSAKPDHPATYPTEDLPYGAVYSLDCNHSHFILVDEDPK---RPGATGEMRVKMLKHISLQRTGYGGTGSIEIPVLCLLVHGEPRILQKMYKNIQNSIPWLILAGSGGVADIL---VTLMDRGCWDADIVQELLINTFPDGLHST--------------EITSWTKLIQRILDHGHLLTVHDPEQDSELDTVILKALVKA----CKSQSQEAQDFLDELKLAVAWNRVDIAKSEIFSGDVQWSAQDLEEVMMEALVNDKPDFVRLFVDNGVNIKQFLTYGRLQELY--CSVSEKNLLHTLLLKKNQERQAQLARKRMSGNPNNELGDRKFRFTFHEVSKVLKDFLDDTCKGFYQKLPAVSKALHQKNLPDMDRRCEHPWRDLFLWAILQNRQEMANYFWAMGPEAVAAALVGCKIMKEMAHLA----TEAESARSMKNAKYEQFAMDLFSECYSNSEDRAYSLLVRKTCCWSKATVLNIATLAEAKCFFAHDGVQALLTKVWWGAMRTDTSISRLVLTFFIPPLVWTSLIKFNPEEQVSKDEGEPFAELDSLETEQALLLTDGDPVAGEGSAETAARSCSATFIRVVLRRWNRFWSAPVTVFMGNVIMYFAFLILFSYVLLLDFRPPPPYGPSAAEIILYFWVFTLVLEEIRQSFFTDEDMSILKKMKLYVEDNWNKCDMVAISLFVVGLSCRMAMST----------YEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDPRIDWV-FRRALYRPYLHIFGQIPLEEIDAAKMPDDNCTTDVQEIILGTLPPCPNIYANWLVILLLVIYLLVTNVLLLNLLIAMFSYTFQVVQENADIFWKFQRYNLIVEYHSRPALAPPFIIISHITQAL 1010
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Zebrafish
Match: trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:ZFIN;Acc:ZDB-GENE-060503-736]) HSP 1 Score: 243.817 bits (621), Expect = 3.081e-65 Identity = 264/1047 (25.21%), Postives = 471/1047 (44.99%), Query Frame = 1
Query: 469 FGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQ-YSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKIS-QKQG----DRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXX---XXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKST-NFRKTFL--------------RLIGRP--------FSKGLNDVKELLSKMI-----GFYEYPCSE-----------------NDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNY-FENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINFFSCILCIIF---PFLISKRTEFTKDFKTCQSESFPDFNEDNCRTS-------------------------------ISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQ---LTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRD-FSWIALSNILDYPYYTMFGVLNLG--NTVYFTWCNASTNYE-----VSNECPE--NNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVL 3303
G I+FTG T K FVRV+ +I ++ +W + L ++++GG ++ ++ +GL+KAA +T A I+T GL GIT +G A++ +S + K++ + +GIAPW ++NR++L AK + ++ SL+ NH+H+I D+ + G R + IS Q+ G + IPV+ L+V G I + + ++ + ++ G+G +DI+ M R C +++ + P+ + ++ K I+ I+ + L+TV D + +LD IL +L+K C S +L L + WNRVDI K +IFSGD+ S + + ++++ K F+ LF++N NI+ FLT L+ELY C S N T L R+ G P F ++V ++L + GFY+ +E + +HP+++LFLWA+L +Q+ A +FW E++ ALV +I K + +E+ + KN +E A+ L EC+ ++ A L+ +K W + L +A+ + F ++ Q + W + L + F P + + +F + + + E P D+ T + + RF+ AP T F + + +F+I FSYV+L + + EI+ ++ ++L++ + F + D + + ++WNK DM+ I +V + R ++ + +T+ +L F L+++ + A HK+LGPKI ++ ++IK++ F + ++L++YGVT+QA +P W+ L PY +FG + L + N +T+ + CP N+L+ +L Y+++ N+LLLN+LIA SY Q + N+ + WK+ Y+LI+EY+ +P L PF +I Q L
Sbjct: 17 LGDIDFTGVSRTRGK---FVRVTSSTDPAEIYQILTKQWGLAPPHLVVALMGGDEVAQLKPWLRDTLRKGLVKAAQSTGAWILTSGLRFGITKNLGQAVRDHSLASTSPKVR----VVAIGIAPWNMIQNRDLLLSAKPDHPATYPTEDLPYGAVYSLDCNHSHFILVDEDPK---RPGATGEMRVKMLKHISLQRTGYGGTGSIEIPVLCLLVHGEPRILQKMYKNIQNSIPWLILAGSGGVADIL---VTLMDRGCWDADIVQELLINTFPDGLHST--------------EITSWTKLIQRILDHGHLLTVHDPEQDSELDTVILKALVKA----CKSQSQEAQDFLDELKLAVAWNRVDIAKSEIFSGDVQWSAQDLEEVMMEALVNDKPDFVRLFVDNGVNIKQFLTYGRLQELY--CSVSEKNLLHTLLLKKNQERQAQLARKRMSGNPNNELGDRKFRFTFHEVSKVLKDFLDDTCKGFYQKLPAERMGKGRLFHSQKNLPDMDRRCEHPWRDLFLWAILQNRQEMANYFWAMGPEAVAAALVGCKIMKEMAHLA----TEAESARSMKNAKYEQFAMDLFSECYSNSEDRAYSLLVRKTCCWSKATVLNIATLAEAKCFFAHDGVQALLTKVWWGAMRTDTSISRLVLTFFIPPLVWTSLIKFNPEEQVSKDEGEPFAELDSLETEQALLLTDGDPVAGEGSAETAARSCSATFIRVVLRRWNRFWSAPVTVFMGNVIMYFAFLILFSYVLLLDFRPPPPYGPSAAEIILYFWVFTLVLEEIRQSFFTDEDMSILKKMKLYVEDNWNKCDMVAISLFVVGLSCRMAMST----------YEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDPRIDWV-FRRALYRPYLHIFGQIPLEEIDAAKMPDDNCTTDVQEIILGTLPPCPNIYANWLVILLLVIYLLVTNVLLLNLLIAMFSYTFQVVQENADIFWKFQRYNLIVEYHSRPALAPPFIIISHITQAL 1015
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Zebrafish
Match: trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:ZFIN;Acc:ZDB-GENE-060503-736]) HSP 1 Score: 243.817 bits (621), Expect = 3.442e-65 Identity = 264/1047 (25.21%), Postives = 471/1047 (44.99%), Query Frame = 1
Query: 469 FGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQ-YSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKIS-QKQG----DRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXX---XXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKST-NFRKTFL--------------RLIGRP--------FSKGLNDVKELLSKMI-----GFYEYPCSE-----------------NDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNY-FENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINFFSCILCIIF---PFLISKRTEFTKDFKTCQSESFPDFNEDNCRTS-------------------------------ISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQ---LTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRD-FSWIALSNILDYPYYTMFGVLNLG--NTVYFTWCNASTNYE-----VSNECPE--NNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVL 3303
G I+FTG T K FVRV+ +I ++ +W + L ++++GG ++ ++ +GL+KAA +T A I+T GL GIT +G A++ +S + K++ + +GIAPW ++NR++L AK + ++ SL+ NH+H+I D+ + G R + IS Q+ G + IPV+ L+V G I + + ++ + ++ G+G +DI+ M R C +++ + P+ + ++ K I+ I+ + L+TV D + +LD IL +L+K C S +L L + WNRVDI K +IFSGD+ S + + ++++ K F+ LF++N NI+ FLT L+ELY C S N T L R+ G P F ++V ++L + GFY+ +E + +HP+++LFLWA+L +Q+ A +FW E++ ALV +I K + +E+ + KN +E A+ L EC+ ++ A L+ +K W + L +A+ + F ++ Q + W + L + F P + + +F + + + E P D+ T + + RF+ AP T F + + +F+I FSYV+L + + EI+ ++ ++L++ + F + D + + ++WNK DM+ I +V + R ++ + +T+ +L F L+++ + A HK+LGPKI ++ ++IK++ F + ++L++YGVT+QA +P W+ L PY +FG + L + N +T+ + CP N+L+ +L Y+++ N+LLLN+LIA SY Q + N+ + WK+ Y+LI+EY+ +P L PF +I Q L
Sbjct: 66 LGDIDFTGVSRTRGK---FVRVTSSTDPAEIYQILTKQWGLAPPHLVVALMGGDEVAQLKPWLRDTLRKGLVKAAQSTGAWILTSGLRFGITKNLGQAVRDHSLASTSPKVR----VVAIGIAPWNMIQNRDLLLSAKPDHPATYPTEDLPYGAVYSLDCNHSHFILVDEDPK---RPGATGEMRVKMLKHISLQRTGYGGTGSIEIPVLCLLVHGEPRILQKMYKNIQNSIPWLILAGSGGVADIL---VTLMDRGCWDADIVQELLINTFPDGLHST--------------EITSWTKLIQRILDHGHLLTVHDPEQDSELDTVILKALVKA----CKSQSQEAQDFLDELKLAVAWNRVDIAKSEIFSGDVQWSAQDLEEVMMEALVNDKPDFVRLFVDNGVNIKQFLTYGRLQELY--CSVSEKNLLHTLLLKKNQERQAQLARKRMSGNPNNELGDRKFRFTFHEVSKVLKDFLDDTCKGFYQKLPAERMGKGRLFHSQKNLPDMDRRCEHPWRDLFLWAILQNRQEMANYFWAMGPEAVAAALVGCKIMKEMAHLA----TEAESARSMKNAKYEQFAMDLFSECYSNSEDRAYSLLVRKTCCWSKATVLNIATLAEAKCFFAHDGVQALLTKVWWGAMRTDTSISRLVLTFFIPPLVWTSLIKFNPEEQVSKDEGEPFAELDSLETEQALLLTDGDPVAGEGSAETAARSCSATFIRVVLRRWNRFWSAPVTVFMGNVIMYFAFLILFSYVLLLDFRPPPPYGPSAAEIILYFWVFTLVLEEIRQSFFTDEDMSILKKMKLYVEDNWNKCDMVAISLFVVGLSCRMAMST----------YEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDPRIDWV-FRRALYRPYLHIFGQIPLEEIDAAKMPDDNCTTDVQEIILGTLPPCPNIYANWLVILLLVIYLLVTNVLLLNLLIAMFSYTFQVVQENADIFWKFQRYNLIVEYHSRPALAPPFIIISHITQAL 1064
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Zebrafish
Match: hrc (histidine rich calcium binding protein [Source:ZFIN;Acc:ZDB-GENE-041008-189]) HSP 1 Score: 242.662 bits (618), Expect = 9.338e-65 Identity = 277/1121 (24.71%), Postives = 504/1121 (44.96%), Query Frame = 1
Query: 277 NYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKE----NKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGR-TVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVG--YFRQALENKIS-QKQGD-RVGIPVVLLIVEGGHDI--FIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSH--EDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIG--------RPFSKGLNDVKELLSKMIGFYEYP----------------------------CSENDSI-KHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGF--NINFFSCILCIIFP------FLISKRTEFTKDFKTCQS-----------ESFPDFNE------------DNCRTS---------------ISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQ---LTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWS----KTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYY-----PQRDFSWIALSNILDYPYYTMFGVLNLG--NTVYFTWCNASTNYEVSNECPE------NNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYI 3291
++I FK C F +++ +C CG ++ H+ + W PT ++G +EF G + + F+R+S + DL+ WK+ L +SV+GG + +++ QGL+KAA +T A IIT GL +GI+ +G+A++ + + + + N + +GIAPWG V+NR L +G Y V N SL+ NH ++ DDG + +K G FR LE+ IS Q+ G+ + IPV+ +++ G + F+E S +K +V G+G ++++ + +Q D ++ + L K+ + +E + D+ + + I +N+ +I++++ K ED + +L L++ N N + +L L +TWNRVDI K ++F+G+I +E + D++ K +F+ L +++ NI +LT L++LY + + + L + + +S L +V +LL+ ++G +P C D + KHP+ LF+WAVL + + A F W CDES+ AL ++ + + +T+ +++ FE +A + C+ + L+ +K++ WG +CLE+A + F S+ Q + W + +L II P F+ ++T+ + K+ + E+ FN+ +N R + + S+ ++F+ AP T F + + F+ ++YV+L K + E + ++ ++ + E F + ++ + + + + + WNK VL L I G+ MF WS + I + F L+++ + A HK+LGPKI ++ K+IK F +L++L++YGV +QA Y P R F +L PY +FG + + +T + + N + NE E +N+L+ IL ++++ NILL+N+LIAT SY + +S WK+ Y+LI+EY+ +P L PF F +I
Sbjct: 21 SWIPKFFKKRLCTTF---VEDSFSYGGRCQCGAMRDDHRSMALGDNFSTAVVSQWLSSQHTSEQPTDAYGDLEFDG---IGRRHSYFLRLSSTTDPARVFDLMKEHWKLQQPNLVVSVVGGEGRSVVKSWVRDVLRQGLVKAAQSTGAWIITGGLRQGISRCVGEAVKDNAAAV-SSITLNKVLP-IGIAPWGLVENRQQLVNLEGSFPARYMVRNI--SPDSCSLDNNHKAFLLVDDG----TSGRKGGELAFRACLEDYISRQRPGNASIDIPVLNMLIAGDTSMLEFLEMS--LKNSTPCLVLAGSGGLANLVSDIVENVQSAAMPGASEEEDASPIM--ELREQLAAKVKKYFPAE-NDTDKLVDKVLSIYQNKDIISIYNAKQEGAEDFEIVMLKVLVQASKRNVSENTNSYADELRLAVTWNRVDIAKSELFNGNIDWKYEELVDSMTDALENNKPQFVRLLIDSGLNILSYLTYGRLEKLYNSISDTCLAKTLLLHHLDERMHESNVQIYSISLYEVSQLLTDLLGEVCHPFYWTELKLEASSTRRKSMKKACRILMGSCKYRDEMCKHPWFCLFIWAVLQNRSEMAIFCWEMCDESVLTALAGCKLLLELSKQEI-ETEAKLSMKELALKFERMAHDVFGTCYLSKASHSYKLLIRKSKLWGDATCLEMAIAADAQIFFSHDGVQSLLSQIWWGDIERGTPLWRILLVIICPPVCYSNFIEYRKTDQAEKEKSVMAPPCSEIDRQYEETVFSFNDNKHQNEAEHKDSENIRRTAKGAPAFIKPKKSSFVVSRWKQFWYAPVTSFIGNLLMYFLFLFLYAYVLLVDFKPPPPDGPAVSEYVLYFWVFTLVCQEIQEAFIA-GNKKFPQTLFLYAQDVWNK-----------FDVLAISLFITGLCCR---MFSWSFNMGRGILCVDYMVFTLRLIYIFAIHKELGPKIIILGKMIKHAFFFLFFLLVWLIAYGVANQALLYQYDPSPARVF-----RRVLYRPYLHIFGDIPVEEIDTGKHWERDCTDNLTLINEGIEPCRDTSHNWLVVILLVIFLLVTNILLINLLIATFSYTFTKVQEHSDKYWKFQRYNLIVEYHSRPTLAPPFIIFSHI 1101
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Xenopus
Match: TRPM1 (transient receptor potential cation channel subfamily M member 1 [Source:NCBI gene;Acc:100216447]) HSP 1 Score: 328.946 bits (842), Expect = 7.633e-92 Identity = 305/1060 (28.77%), Postives = 513/1060 (48.40%), Query Frame = 1
Query: 421 ESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYN-VSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDI--FIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYET--CPKST------NFRKTFLRLIGRPFSKGLNDVKELLSKMIGFYEYPC--------------------------------------------SENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDT---DRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN---FFSCILCIIFP---FLISKRTEFTKDFKT---------------CQSESFPDFNEDNC-----RTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNE-------CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVL 3303
E WS ++ PT +FG +EF G +N + ++RVSY K D ++ L+ +W++ L ISV GG +F+M K K +F +GLIKAA+TT A I T G++ G+ +GDA++ S K I +GIAPWG V+N+ L K T Y +SN + K LN +HTH+I D+G T K G R+ LE IS QK R+ G+PVV LIVEGG ++ + R + V +VVC+G+G+ASDI+ A HK G+ + ES ++ L + + +Q + + + + +K + LITVF + S +D++ AIL +L+K + QLSL L WNRVDI + +IF + D+++ +V F++L +EN ++Q FLT L+ELY T P +T + +K + + L D+ +L ++G Y C E K+PF EL +WAVL+++QK A F W + +E++ ALVA ++YK S D S+ L+ F LA++L+++ + D++VA L+ + +NW +CL+LA + F+++ Q + W + I+ I+FP + R++ F T ++ + +E+N I +K+ FY AP KF ++ +++++++ F+YV+L M+R ++ E + + Y+V + L+K EI S ++ ++K W +WN D++ I ++ +LR Q N Y + + IY + + +Y+++L + +K LGP + M+ K++ ++L F I+L+ L+S+GV QA +P + SW NI PY+ ++G V+ + + +E C +L P L A Y+++ NILL+N+LIA + ++ S +WK+ Y LI+ ++D+P+LP P F ++Y +L
Sbjct: 18 EKWSISKHTQLSPTDAFGILEFQGGGHSNKAM--YIRVSYDSKPDSLLHLMVKEWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVIRHVGDALKDHSS------KSRGRICAIGIAPWGIVENKEDL-IGKDVTKPYQTMSNPLSKLS--VLNSSHTHFILADNG-----TLGKYGAEVKLRRQLEKHISLQKINTRLGQGVPVVALIVEGGPNVITIVLECLREEPPVPVVVCDGSGRASDIMSFA----------HKYSEEGGI--ISESLRDQLLVTIQKTFNYSRNQAHQLLVVLMECMKKKELITVFRMGSEGQQDIEMAILTALLKGTN-------ASAPDQLSLALAWNRVDIARSQIFVFGHHWPVSSLEQAMMDALVLDRVDFVKLLIENGVSMQRFLTIPRLEELYNTRLGPPNTLHYIVRDVKKVGFGNLPPDYHVSLIDIGLVLEYLMGG-AYRCHYTRKTFRTLYNNLFGPKRDDEPPTKGKKKKKKKEEEIDMDVDDPEVSRFKYPFHELMVWAVLLKRQKMALFLWQRGEETMAKALVACKLYKSMAHESSESELVDDISQDLDNNSKDFGQLALELLDQSYKHDEQVAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILFPPTILFLEFRSQDDLSFHTSKEYEEGKEKEDENMVRNTTSRKGDEENGNRKQKSIPIGTKIYEFYNAPIVKFWFYTISYLAYLMLFNYVILVKMERWP-SVQEWVVISYIVTLALEKVREILMSEPGKLSQKVKVWLQ-EYWNITDLVAISVFLIGAILRLQ---NQPY------MGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVIIMLVVLMSFGVARQAILHPDEEPSWRLARNIFYMPYWMIYG------EVFADQIDPPCGENLYDEDGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIIFSHLYIIL 1024
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Xenopus
Match: TRPM6 (transient receptor potential cation channel, subfamily M, member 6 [Source:NCBI gene;Acc:100487366]) HSP 1 Score: 316.235 bits (809), Expect = 1.337e-87 Identity = 302/1107 (27.28%), Postives = 503/1107 (45.44%), Query Frame = 1
Query: 358 KCSCGEIKKSHK--ENKIPYGPR------ESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVG---YFRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDIFIEASRRVK--EKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHE--DLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNF------------------------------------------RKTFLRLIGRPF-----SKGLNDVKELLSKMIGFYEYPC-------SENDSIK--HPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDT---DRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNI---NFFSCILCIIFPFLI-----SKRTEFTKDFKTCQSESF-------PDFNEDNCR--------TSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMF--------RW--------SKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVL-AFCYQKGR 3327
KC CG + H + P P E WS + + PT +FG I F D T ++R+SY L+ ++ L+ +W++ L ISV GG +FK+ K K +F +GL+KAA TT A I+T G+N G + +GDA++ S +H I +GI PWG ++N+ L ++ + N + K SLN H+H+I DDG T K G R+ LE+ IS QK R+ G+PVV L++EGG ++ + V+ V +VVCEGTG+A+DI+ AF + ++ + + M+ ++F N+ R Q + + + + ++ IT+FD +S E D+D AIL +L+K ++ QLSL LTWNRVDI K I ++D+++ +V F++L +E N+ FLT L+ELY T TN RK+F L F S L + L PC +N+ + +P+ +L +WAVLM++QK A FFW +E++ A++A ++Y+ + + T D SE L+ + F LA+ ++E +++++A L+ + +NW +CL+LA ST F+S+ Q + W + ++ IL I+ P + + E + ++ + F P ED + I+ K+ FY AP KF H+ +++F++ F+Y VL M Q ++ E +IY+ ++K E+F S + ++K W +WN TD + +F RW + IY L + +Y+++L A +++ GP I M+ K+ + I+ I LL++GV+ +A P SW +I+ PY+ MFG VY +A E +CP +F+ P L A Y+ + I+++N+LI+ + + + ++ S +WKY+ Y I+ Y +KP LP P +IY ++ C+ +
Sbjct: 35 KCCCGRLIGDHPGLDYGWPINPSPQEREDEEWSILNHTKPSPTDAFGTINFQDGDHTYH--AKYIRISYDTTLELLMHLMIKEWQMELPKLVISVHGGIQNFKLPSKIKQVFGKGLVKAAETTGAWILTEGINTGASKHVGDALKAHAS------QHLRKICAVGIPPWGAIENQQDLIGKDVVCLYQTLINPMSKL--TSLNSMHSHFIMVDDG-----TVGKYGNEMKLRRNLEDFISLQKIHTRMGQGVPVVGLVIEGGPNVILMVWEYVRSTPPVPVVVCEGTGRAADIL--AFTH-KHTTDTDPQLKEEILEMIQKTF-NLGHR-----------QSNHVLYILMECMERRASITIFDAESEEQQDIDLAILTALLKGTNM-------SAQDQLSLALTWNRVDIAKKHILIYGQHWKVGSLEQAMQDALVMDRVDFVKLLIEYGVNMHRFLTIGHLEELYNTKQGPTNLLLHHLVRDVKQSNPSPDYRISLIDVGLVIEYLIGGAYRSSYTRKSFRVLYNSLFRKHKMSSKLESPESTLHSQFFRTAQPCRHEVTCTEDNEPVGFIYPYNDLLVWAVLMKRQKMAMFFWQHGEEAMVKAVIACKLYRAMAHEAKQSTMVDDTSEELKKYSKEFGQLALDILENAFKMNEQMAMKLLTYQLKNWSNSTCLKLAVSSTLRPFVSHTCTQMLLTDMWMGRLKMRKHSWLKVILGILLPPFVLMLEFKTKAEMSHVPQSLEFHQFSRLYVDPPSLREDQNQKISNGLGILPITRKICEFYSAPIVKFWFHTMVYLAFLMLFTYTVLVKMDP-QPSVQEWCVIIYIFTTAVEKVREVFVSEPGKFSQKVKVWIN-EYWN-------------------------LTDSIAIFLFFIGFGLRWPDPPFQTAGRIIYCLDIIFWYVRLLDFFAVNQQAGPYITMLGKMTSNMFGIVIIMAIVLLAFGVSRKAILSPDHPPSWTLARDIVFQPYWMMFG------EVYAGEIDAC---EEDPDCPPGSFITPFLQAVYLFVQYIIMVNLLISLFNNVYRVLNSVSHKLWKYNRYRYIMTYYEKPWLPPPLIFLSHIYILINRLCHHRSH 1068
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Xenopus
Match: TRPM1 (transient receptor potential cation channel subfamily M member 1 [Source:NCBI gene;Acc:100216447]) HSP 1 Score: 306.605 bits (784), Expect = 1.034e-84 Identity = 292/992 (29.44%), Postives = 483/992 (48.69%), Query Frame = 1
Query: 571 IFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYN-VSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDI--FIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNF------------------------RKTFLRLIGRPFSKGLNDVKELLSKMIGFY--EYPC-------------------SENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDT---DRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN---FFSCILCIIFP---FLISKRTEFTKDFKTCQ-----SESFPDFNEDNCR----TSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNE-------CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVL 3303
+ +W++ L ISV GG +F+M K K +F +GLIKAA+TT A I T G++ G+ +GDA++ S K I +GIAPWG V+N+ L K T Y +SN + K LN +HTH+I D+G T K G R+ LE IS QK R+ G+PVV LIVEGG ++ + R + V +VVC+G+G+ASDI+ A HK G+ + ES ++ L + + +Q + + + + +K + LITVF + S +D++ AIL +L+K + QLSL L WNRVDI + +IF + D+++ +V F++L +EN ++Q FLT L+ELY T ++ RKTF L F G K L K++G E P E K+PF EL +WAVL+++QK A F W + +E++ ALVA ++YK S D S+ L+ F LA++L+++ + D++VA L+ + +NW +CL+LA + F+++ Q + W + I+ I+FP + R++ F T + + S E+ R I +K+ FY AP KF ++ +++++++ F+YV+L M+R ++ E + + Y+V + L+K EI S ++ ++K W +WN D++ I ++ +LR Q N Y + + IY + + +Y+++L + +K LGP + M+ K++ ++L F I+L+ L+S+GV QA +P + SW NI PY+ ++G V+ + + +E C +L P L A Y+++ NILL+N+LIA + ++ S +WK+ Y LI+ ++D+P+LP P F ++Y +L
Sbjct: 1 MVKEWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVIRHVGDALKDHSS------KSRGRICAIGIAPWGIVENKEDL-IGKDVTKPYQTMSNPLSKLS--VLNSSHTHFILADNG-----TLGKYGAEVKLRRQLEKHISLQKINTRLGQGVPVVALIVEGGPNVITIVLECLREEPPVPVVVCDGSGRASDIMSFA----------HKYSEEGGI--ISESLRDQLLVTIQKTFNYSRNQAHQLLVVLMECMKKKELITVFRMGSEGQQDIEMAILTALLKGTN-------ASAPDQLSLALAWNRVDIARSQIFVFGHHWPVSSLEQAMMDALVLDRVDFVKLLIENGVSMQRFLTIPRLEELYNTGNLPPDYHVSLIDIGLVLEYLMGGAYRCHYTRKTFRTLYNNLF--GPKRPKAL--KLLGMEDDEPPTKGKKKKKKKEEEIDMDVDDPEVSRFKYPFHELMVWAVLLKRQKMALFLWQRGEETMAKALVACKLYKSMAHESSESELVDDISQDLDNNSKDFGQLALELLDQSYKHDEQVAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILFPPTILFLEFRSQDDLSFHTSKEYEEDTTSRKGDEENGNRKQKSIPIGTKIYEFYNAPIVKFWFYTISYLAYLMLFNYVILVKMERWP-SVQEWVVISYIVTLALEKVREILMSEPGKLSQKVKVWLQ-EYWNITDLVAISVFLIGAILRLQ---NQPY------MGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVIIMLVVLMSFGVARQAILHPDEEPSWRLARNIFYMPYWMIYG------EVFADQIDPPCGENLYDEDGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIIFSHLYIIL 938
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Xenopus
Match: ENSXETT00000055613.1 (transient receptor potential cation channel subfamily M member 7-like [Source:NCBI gene;Acc:100497855]) HSP 1 Score: 305.064 bits (780), Expect = 5.133e-84 Identity = 293/1131 (25.91%), Postives = 525/1131 (46.42%), Query Frame = 1
Query: 358 KCSCGEIKKSHKENKIPYGPR--------ESWSEGDCMEMLPTYSFGKIEFT-GEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQKQ-GDRVG--IPVVLLIVEGGHDIFIEASRRVKE--KVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFK----NVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLI--------------------------------GRPFSKGLNDVKELLSKMIGFY--EYPCSENDSIK----------HPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYK-YHQRTSLRDT--DRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN---FFSCILCIIFPFLI-----------SKRTEFTKDFK---------TCQSESFPDFNEDN--CRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNSKLHIDKPMAFKHDTLNIFSNIKSDSDLNK 3465
+C CG + K H GP E W+ T +FG I+F G +K F+R+S K++DI+ L+ +W + L ISV GG F++H + K F +G +KAA++T A I T G N G+ + IGDAI+ + ++ HN IS +G+APWG ++ R L + + + + K LN H+H++ DDG T + G R+ LENK S +Q + G +P++ LI+EGG + +++ V +VVCEGTG+A+D++ HK S G +LP+ + +++K+ LH + C++ + LITV I H+++D +L +L+K ++ +L L L W+RVDI K+ IF + D++I +V+F++L +EN ++Q FLT L ELY +++ T L+LI R K + + LS+ G + S ND+++ +PF +L +WAVL ++QK A FFW +ES+ ALVAT++Y+ +Q D D SE L+ + F LAV+L+++ + +A L+ + +NW +CL+LA S F+S+ Q + W N+ ++ I I FP +I S + D+K TC E + + R I+ + FY AP KF + + +++F++ +++VVL M+ + ++ E + ++ ++ ++K EIF S + ++ +++ W++ ++ N D I I+ +V LR+ D ++ IY L +++++L +L+ +++ GP + M+ K++ + I++I L++YG+ +A YP D SW ++L +PY+ ++ G + + V + C ++ P L A Y+++ ++++N++IA +++ S +IWK Y I+ ++ KP+LP P Y+ + + + + + K + + KLH F+ + I+ K D + NK
Sbjct: 38 RCCCGRLIKQHAYYASGAGPSGAAHVQESEHWTVDRHTVKSSTDAFGTIDFQCGSHGYKAK---FIRLSDDSKVEDILQLMIKEWHMKRPNLVISVHGGMQKFELHPRFKEAFGKGFVKAAVSTGAWIFTGGTNNGVAAHIGDAIKEYAT----RLTHN--ISIIGVAPWGIIEGRQDLIGNNVMAPYQTLLSPLSKLH--VLNNLHSHFLLVDDG-----TAGRTGGEINLRRELENKTSLQQFNAKTGRHVPMMALILEGGPKTILTVLEYLQQSPPVPVVVCEGTGRAADLLAYV----------HKHTESSG--LLPDGMESNVISIIKKTFTLNKNEALHLFQTLMCCMQ----MKELITVLHIGPDIHQEIDVDLLKALLKGNNI-------SPIDRLHLALAWDRVDIAKNHIFVRGQQWLVKPLEQVMMDALIMDRVEFVKLLIENGVSMQKFLTIPRLDELYNVVDTNSD---TLLQLILEIKKGNVPGKYKITMMDVGLVIEYLMGGVFRSRYTKKNFKAMYKALSQTSGTHGDSQKSSRNDALEADNQITRPFPYPFNDLLVWAVLTKRQKMALFFWQHGEESMAKALVATKLYRGMYQEAQQSDIIDDSSEKLKKYSKEFGELAVELLDQSFKQNDLMAMKLLTYELKNWSKSTCLKLAVSSRLRTFVSHTCTQMLLNDMWMGRLNMRKNAWYKVISGIFFPPIIPLFDYKTMAQMSHIPQSQDDYKMNLDDKEEITCSVEGIALVSNEGKPKRVPIARRFYAFYHAPIVKFWLSTLVYMAFLMLYAFVVLVKMESLP-SVQEWIVILSILTTGVEKIREIFMSEAGKLTQKLRVWFS-SYLNINDAIAIITFLVGFGLRFG------GRDFIL-------IYCLNTIFWFIRLLDILSVNQEAGPYVLMVGKMVMSMFYVVVIMVIVLITYGIPRKAILYPHEDPSWTLAKDVLFHPYFMIY-----GEVFAYEIDVCGNDSAVPHLCGTGTWITPFLEATYLLVNYVIMVNLIIAVFNHVYLQYKSMSNIIWKCQRYKFIMAFHSKPVLPPPLIILSYVTSLFSCVFLRKQKNKTHGPKLYLTEEEQKKLH-----EFEEHCVGIYLIYKEDKNKNK 1101
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Xenopus
Match: aldh3a2 (aldehyde dehydrogenase 3 family member A2 [Source:Xenbase;Acc:XB-GENE-942662]) HSP 1 Score: 299.671 bits (766), Expect = 3.890e-82 Identity = 311/1131 (27.50%), Postives = 517/1131 (45.71%), Query Frame = 1
Query: 274 RNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHK---------ENKIPYG------PRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDI--FIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANI-----------------LKELYETCPKSTNFRKTFLRLIG--RPFSKGLNDVKELLSKMIGFYEYPCSEND--------SIKH---PFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRD---TDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNI---NFFSCILCIIFPFLI---------------------SKRTEFTKDFKTCQSESFPDF---------NEDNCRT------------SISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNE---------CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMP---FSTFVYIYQVLAFCYQK 3321
+++I F EC + + K+ +C CG + H +N+ G E WS G ++ PT +FG IEF G +N + +VR+S+ K D ++ L+ +W++ L ISV GG +F++ K K +F +GLIKAA+TT A I T G+N G+ +GD+++ S K I +GIAPWG V+N+ L + +SN + K LN H+H+I D+G T K G R+ LE IS QK R+ G+PVV LIVEGG ++ + R V +VVC+G+G+ASDI+ AF HK G ++ ES ++ L + + Q + + +K + LITVF + S H+D+D AIL +L+K + QLSL L WNRVDI + +IF + D+++ +V F++L +EN ++ N+ + Y FR + L G RP + L +++ + G E + I H PF EL +WAVLM++QK A FFW +E++ ALVA ++ K + + D S+ L F LAV+L+++ + D+++A L+ + +NW +CL+LA + F+++ Q + W + + IL I+ P I + E + KT + + D N D+ R I K+ FY AP KF + ++ +++ F+Y+VL M R ++ E + + Y+ + ++K EI S ++ + K W +WN D++ I+ + MVLR Q Y + IY + + +Y+++L + +K LGP + M+ K++ +++ F I+L+ L+S+GV QA +P + SW NI PY+ ++G V+ + Y V+ E C +++P + A Y+++ NILL+N+LIA + ++ S +WK+ Y LI+ ++++P+LP P FS F I + L ++K
Sbjct: 62 KSWIERAFHKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISIIQNEKNEGRHRNDIQSEKWSIGKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLKDHAS------KSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPMSKL--TVLNSMHSHFILADNG-----TTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDIL--AF--------GHKYSEEGG--LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGAN-------ASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHPTSPLNVKYNLISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPIRSGRKTTKKREEEIDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSSLKVILGILLPPSILSLEFKNKDEMPYMSQANEMDLQEKEVEEPDKTVKEKEEDDMELTAMLARGNGDSSRKKDEDEHPRHRLIPIGRKIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVKMDRWP-SMQEWIVISYIFTLGIEKMREILMSEPGKLLQKFKVWLQ-EYWNLADLVSILLFSIGMVLRLQEQPFSSY---------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPSEEPSWNLAKNIFYMPYWMIYG------EVFADQIDPPCGYNVTGEDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHFTMICKHLCCRWRK 1137
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101]) HSP 1 Score: 301.597 bits (771), Expect = 7.731e-83 Identity = 318/1154 (27.56%), Postives = 525/1154 (45.49%), Query Frame = 1
Query: 274 RNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSH--------------KENKIPYG--PRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTV---HYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDI--FIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAA-----FLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTN---------------------------------------------FRKTFLRLIGR-----PFSKGLNDVKELLSKMIGFYEYPCSENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRD---TDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNI---NFFSCILCIIFPFLI--------------------------------------SKRTEFTKDFKTCQSESFPDFNEDNCRT-----SISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRW-SKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNE---------CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMP---FSTFVYIYQ 3297
+++I F EC + + K+ +C CG + H E+++ E WS ++ PT +FG IEF G +N + +VRVS+ K D ++ L+ +W++ L ISV GG +F++ K K +F +GLIKAA+TT A I T G+N G+ +GDA++ S K I +GIAPWG V+N+ L GR V + +SN + K LN H+H+I D+G T K G R+ LE IS QK R+ G+PVV LIVEGG ++ + R V +VVC+G+G+ASDI+ AF HK G ++ ES ++ L + + Q + + +K + LITVF + S H+D+D AIL +L+K + QLSL L WNRVDI + +IF + +W + D+++ +V F++L +EN ++ FLT + L+ELY T +N FR + L G P +G K+ ++ + P E + PF EL +WAVLM++QK A FFW +E++ ALVA ++ K + + D S+ L F LAV+L+++ + D+++A L+ + +NW +CL+LA + F+++ Q + W + + IL I+ P I + E T ES +E+ ++ + K+ FY AP KF ++ +I +++ F+Y+VL M+R T E + + Y+ + ++K EI S ++ ++K W +WN D+I I+ V M+LR Q D+ FR + IY + + +Y+++L + +K LGP + M+ K++ +++ F I+L+ L+S+GV QA +P + SW NI PY+ ++G V+ + + E C +++P + A Y+++ NILL+N+LIA + ++ S +WK+ Y LI+ ++++P+LP P FS I+Q
Sbjct: 62 KSWIERAFYKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHAS------KSRGKICTIGIAPWGIVENQEDL---IGRDVVRPYQTMSNPMSKL--TVLNSMHSHFILADNG-----TTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDIL--AF--------GHKYSEEGG--LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGAN-------ASAPDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDP--EINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILRLQ--------DQP--FRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYG------EVFADQIDPPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQ 1149
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101]) HSP 1 Score: 300.442 bits (768), Expect = 1.416e-82 Identity = 318/1154 (27.56%), Postives = 525/1154 (45.49%), Query Frame = 1
Query: 274 RNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSH--------------KENKIPYG--PRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTV---HYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDI--FIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAA-----FLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTN---------------------------------------------FRKTFLRLIGR-----PFSKGLNDVKELLSKMIGFYEYPCSENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRD---TDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNI---NFFSCILCIIFPFLI--------------------------------------SKRTEFTKDFKTCQSESFPDFNEDNCRT-----SISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRW-SKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNE---------CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMP---FSTFVYIYQ 3297
+++I F EC + + K+ +C CG + H E+++ E WS ++ PT +FG IEF G +N + +VRVS+ K D ++ L+ +W++ L ISV GG +F++ K K +F +GLIKAA+TT A I T G+N G+ +GDA++ S K I +GIAPWG V+N+ L GR V + +SN + K LN H+H+I D+G T K G R+ LE IS QK R+ G+PVV LIVEGG ++ + R V +VVC+G+G+ASDI+ AF HK G ++ ES ++ L + + Q + + +K + LITVF + S H+D+D AIL +L+K + QLSL L WNRVDI + +IF + +W + D+++ +V F++L +EN ++ FLT + L+ELY T +N FR + L G P +G K+ ++ + P E + PF EL +WAVLM++QK A FFW +E++ ALVA ++ K + + D S+ L F LAV+L+++ + D+++A L+ + +NW +CL+LA + F+++ Q + W + + IL I+ P I + E T ES +E+ ++ + K+ FY AP KF ++ +I +++ F+Y+VL M+R T E + + Y+ + ++K EI S ++ ++K W +WN D+I I+ V M+LR Q D+ FR + IY + + +Y+++L + +K LGP + M+ K++ +++ F I+L+ L+S+GV QA +P + SW NI PY+ ++G V+ + + E C +++P + A Y+++ NILL+N+LIA + ++ S +WK+ Y LI+ ++++P+LP P FS I+Q
Sbjct: 64 KSWIERAFYKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHAS------KSRGKICTIGIAPWGIVENQEDL---IGRDVVRPYQTMSNPMSKL--TVLNSMHSHFILADNG-----TTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDIL--AF--------GHKYSEEGG--LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGAN-------ASAPDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDP--EINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILRLQ--------DQP--FRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYG------EVFADQIDPPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQ 1151
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101]) HSP 1 Score: 290.426 bits (742), Expect = 2.769e-79 Identity = 314/1146 (27.40%), Postives = 524/1146 (45.72%), Query Frame = 1
Query: 274 RNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSH--------------KENKIPYG--PRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTV---HYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDI--FIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAA-----FLKDSIITGKVKFIELFLENVSN---------IQDFLTAN--------------ILKELYETCPKSTNFRKTF---------------LRLIGR----PFSKGLNDVKELLSKMIGFYEYPCSENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRD---TDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNI---NFFSCILCIIFPFLI--------------------------------------SKRTEFTKDFKTCQSESFPDFNEDNCRT-----SISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRW-SKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNE---------CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMP---FSTFVYIYQ 3297
+++I F EC + + K+ +C CG + H E+++ E WS ++ PT +FG IEF G +N + +VRVS+ K D ++ L+ +W++ L ISV GG +F++ K K +F +GLIKAA+TT A I T G+N G+ +GDA++ S K I +GIAPWG V+N+ L GR V + +SN + K LN H+H+I D+G T K G R+ LE IS QK R+ G+PVV LIVEGG ++ + R V +VVC+G+G+ASDI+ AF HK G ++ ES ++ L + + Q + + +K + LITVF + S H+D+D AIL +L+K + QLSL L WNRVDI + +IF + +W + D+++ +V F++L +EN + ++D N +++ L + RK F L+L+G P +G K+ ++ + P E + PF EL +WAVLM++QK A FFW +E++ ALVA ++ K + + D S+ L F LAV+L+++ + D+++A L+ + +NW +CL+LA + F+++ Q + W + + IL I+ P I + E T ES +E+ ++ + K+ FY AP KF ++ +I +++ F+Y+VL M+R T E + + Y+ + ++K EI S ++ ++K W +WN D+I I+ V M+LR Q D+ FR + IY + + +Y+++L + +K LGP + M+ K++ +++ F I+L+ L+S+GV QA +P + SW NI PY+ ++G V+ + + E C +++P + A Y+++ NILL+N+LIA + ++ S +WK+ Y LI+ ++++P+LP P FS I+Q
Sbjct: 62 KSWIERAFYKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHAS------KSRGKICTIGIAPWGIVENQEDL---IGRDVVRPYQTMSNPMSKL--TVLNSMHSHFILADNG-----TTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDIL--AF--------GHKYSEEGG--LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGAN-------ASAPDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDP--EINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILRLQ--------DQP--FRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYG------EVFADQIDPPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQ 1141
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101]) HSP 1 Score: 288.886 bits (738), Expect = 7.378e-79 Identity = 350/1324 (26.44%), Postives = 583/1324 (44.03%), Query Frame = 1
Query: 274 RNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSH--------------KENKIPYG--PRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTV---HYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDI--FIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLEN----VSNIQDFLTANILKELYE---------TCPKS--------------------------TNFRKTFLRLIGR-----PFSKGLNDVKELLSKMIGFYEYPCSENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRD---TDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNI---NFFSCILCIIFPFLI--------------------------------------SKRTEFTKDFKTCQSESFPDFNEDNCRT-----SISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRW-SKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNE---------CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMP---FSTFVYIYQVLAFCYQKG------RCYNLSNSKKFEITKHNSKLH------IDKPMAFKHDTLNIFSNIKSDSDLNKLIKYFENYSQKFVIKNIAIEKQKSIKSGISRMEIRSKSIFKELENIQTKLNKI----QIKNVKKVQEGSFTNTNGEYQNITKQPKDSMALLLTSLNNNILVLQDEVNRIGQEV 3792
+++I F EC + + K+ +C CG + H E+++ E WS ++ PT +FG IEF G +N + +VRVS+ K D ++ L+ +W++ L ISV GG +F++ K K +F +GLIKAA+TT A I T G+N G+ +GDA++ S K I +GIAPWG V+N+ L GR V + +SN + K LN H+H+I D+G T K G R+ LE IS QK R+ G+PVV LIVEGG ++ + R V +VVC+G+G+ASDI+ AF HK G ++ ES ++ L + + Q + + +K + LITVF + S H+D+D AIL +L+K + QLSL L WNRVDI + +IF + D+++ +V F++L +EN SN L ++ K Y P FR + L G P +G K+ ++ + P E + PF EL +WAVLM++QK A FFW +E++ ALVA ++ K + + D S+ L F LAV+L+++ + D+++A L+ + +NW +CL+LA + F+++ Q + W + + IL I+ P I + E T ES +E+ ++ + K+ FY AP KF ++ +I +++ F+Y+VL M+R T E + + Y+ + ++K EI S ++ ++K W +WN D+I I+ V M+LR Q D+ FR + IY + + +Y+++L + +K LGP + M+ K++ +++ F I+L+ L+S+GV QA +P + SW NI PY+ ++G V+ + + E C +++P + A Y+++ NILL+N+LIA + ++ S +WK+ Y LI+ ++++P+LP P FS I+Q + ++K R Y L K F K+H I++ K D N +D + + EN S + N E++ S+K+ + ++IR + + + T L ++ + ++ K S T+ Y I +Q S N LQ+ ++ G+E
Sbjct: 62 KSWIERAFYKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHAS------KSRGKICTIGIAPWGIVENQEDL---IGRDVVRPYQTMSNPMSKL--TVLNSMHSHFILADNG-----TTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDIL--AF--------GHKYSEEGG--LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGAN-------ASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDP--EINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILRLQ--------DQP--FRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYG------EVFADQIDPPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHVCCRWRKHESDQDERDYGL---KLFITDDELKKVHDFEEQCIEEYFREKDDRF----NSSNDERIRVTSERVENMSMRLEEVN---EREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAY--IVRQSS------FNSQEGNTFKLQESIDPAGEET 1306
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Mouse
Match: Trpm2 (transient receptor potential cation channel, subfamily M, member 2 [Source:MGI Symbol;Acc:MGI:1351901]) HSP 1 Score: 248.825 bits (634), Expect = 2.090e-66 Identity = 276/1074 (25.70%), Postives = 489/1074 (45.53%), Query Frame = 1
Query: 277 NYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKI-PYGPR-ESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVG----IPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISEL----------HQVDEAIKCIEDIIKNELLITVF--DIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGR----PFSKG-----LNDVKELLSKMIG-----FYEYPCSEND-----SIKH--------------------------PFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN--FFSCILCII-FPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVL--MILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGY-YPQRDFSWIALSNILDYPYYTMFGVLNL---GNTVYFTWCNASTNYEVSNECPENN----------FLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDK 3252
++I K EC YF + K D C+CG + H E I P+ + + W ++ +PT +FG I FT D++ K+ +VRVS I L+ W + L ISV GG +F M + K+IF +GL+K A TT A IIT G + G+ +G+A++ L K I+ +G+A WG + NR L G + +E + L+ NH+H+I DDG Q + R LE IS++ +R G IP+V +++EGG + V+ EG+G+ +D+I + VA LP S + LI+Q +S +Q+ E K I+DI++ L+T+F +D+D AIL +L+K QL L + WNRVDI + +IF+ + + + ++I+ K +F+ LFLEN +++F+T + L LYE S F +++ ++ ++ V ++L +++G Y P + ++ H P ++L +WAV+ ++ A W + + AL ++I K + E L + FE+ A+ + EC+ D+E A L+ + +E WG +CL+LA ++ D+KF+S+ Q + W ++ + ILC++ FP L + F + K Q+ CR +++R F+ AP F ++ ++ +F+ F+YV+ M Q + ++IYL L ++ ++ ++F ++ + + WNK+D+ I+ IV + R L +Y ++++ SL F L+++ + K LGPKI ++ +++K++ F ++ ++++S+GV QA + + WI ++ + Y T+FG + G C+ + +CPE++ +L L Y++ NILLLN+LIA +Y Q++ ++ IWK+ + LI EY+ +
Sbjct: 60 SWIPENIKKKECVYFVESSKLSDAGKVVCACGYTHEQHLEVAIKPHTFQGKEWDPKKHVQEMPTDAFGDIVFT--DLSQ-KVGKYVRVSQDTPSSVIYQLMTQHWGLDVPNLLISVTGGAKNFNMKLRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVR--DFSLSSSCKEGEVIT-IGVATWGTIHNREGLIHPMGGFPAEYMLDEEGQGNLTCLDSNHSHFILVDDGTHGQYGVEIP--LRTKLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIYNAINNGTPCVIVEGSGRVADVIAQ-------------------VATLPVSEITI---SLIQQKLSIFFQEMFETFTENQIVEWTKKIQDIVRRRQLLTIFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFTDEWQWKPADLHPMMTAALISNKPEFVRLFLENGVRLKEFVTWDTLLCLYENLEPSCLFHSKLQKVLAEEQRLAYASATPRLHMHHVAQVLRELLGDSTQLLYPRPRYTDRPRLSMTVPHIKLNVQGVSLRSLYKRSTGHVTFTIDPVRDLLIWAVIQNHRELAGIIWAQSQDCTAAALACSKILKELSKEEEDTDSSEEMLAL-ADEFEHRAIGVFTECYRKDEERAQKLLVRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLCVDNGLWRIILCMLAFPLLFTGFISFRE--KRLQAL---------CR---PARVRAFFNAPVVIFHMNILSYFAFLCLFAYVL---MVDFQPSPSWCEYLIYLWLFSLVCEETRQLFYDPDGCGLMKMASLYFSDFWNKLDVGAILLFIVGLTCR--LIPATLYPGRIIL--------SLDFIMFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNESRVDWI-FRGVVYHSYLTIFGQIPTYIDGVNFSMDQCSPNGTDPYKPKCPESDWTGQAPAFPEWLTVTLLCLYLLFANILLLNLLIAMFNYTFQEVQEHTDQIWKFQRHDLIEEYHGR 1074
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. UniProt/SwissProt
Match: sp|A0A0R4IMY7|TRPM2_DANRE (Transient receptor potential cation channel subfamily M member 2 OS=Danio rerio OX=7955 GN=trpm2 PE=1 SV=2) HSP 1 Score: 281.952 bits (720), Expect = 4.939e-76 Identity = 286/1101 (25.98%), Postives = 509/1101 (46.23%), Query Frame = 1
Query: 277 NYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGPR----ESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQ-KQGDR---VGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQD---ISELHQVDEAIKCIEDIIKNELLITVFDIKSHE--DLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLT-ANILKELYETCPKSTNFRKTFLRLIGRPFSKG-----------LNDVKELLSKMIGFY---------------------------EYPCS----ENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIY-KYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN--FFSCILCII-FPFL------------ISKRTEFTKDFKTCQSESFPDFNEDNCRTSI--------------SSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRD-FSWIALSNILDYPYYTMFG--VLNLGNTVY-FTWCNASTNYEVSNECP----ENNFLIP-----ILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPF 3273
++I K EC ++ D + C CG K H + I P E W + + PT +FG I F G K +VRVS +++ L+ +WK+ + L ISV GG +F + K+ F +GLIK A TT A I+T G + G+ +G A+ + Y I +G+APWG + NR+ L +GR Y +E + + L+ NHTH++ DDG T+ G R LE IS+ G+R V IPVV ++++GG + VV EG+G+ +D+I + S V+ + + N L ++ Q+ +EL Q+ E K I+DI++ L+TVF I + D+D AIL +L+K + ++ QL L + WNRVDI + +IF+ + ++ + + +++ K +F+ L LEN +++FL L ELY P RK R+ G +G L+ V E + ++G + + PCS D++ P ++LFLWAV+ ++ A+ W +C + + AL A++I K Q + D++ + + N++E A+ + ECH D + A L+ + + +WG +CL LA ++ D F+++ Q + W +++ + +LC+I FP + I ++ E T+ K F ++ + + SS+L F +PQ KF + ++ F+ F+ V++ + + E++ ++L ++ ++ +++ + R + + WN +D++ IV I ++ R Q + Y KV++ I+ F L+++ + + + LGPKI ++ +++ +L F ++ I++++YGV Q + +WI + + PY T+FG N+ NT++ + C+ + + + +CP +N + P ++ Y++ NILLLN+LIA +Y Q++ N+ IWK+ Y LI EY+ +P LP PF
Sbjct: 38 SWIKENIKKKECCFYVE-----DGREGICKCGYPKVQHCDEAI--KPEDYMGEQWDKHRHVRETPTDAFGDISFGG---LGQKTGKYVRVSSDTSCENLYQLMTEQWKLRSPNLLISVTGGAKNFYIKTHLKDKFRRGLIKVAQTTGAWILTGGTHAGVMKHVGMAV---RDYTLSSGSMEGQIVVIGVAPWGVIHNRSTLIHPEGRFPAYYSLDEQGQGRLSCLDINHTHFLLVDDG-----TQGHYGVEIELRARLEKLISKLSLGNRESGVTIPVVCVVLDGGPGTLNTIYNSMLNHTPCVVLEGSGRLADVIAH--------------VASVPVSKVTMALINRLLKRFFMQEYKNFTEL-QIIEWTKKIQDILRMPHLLTVFRIDEDKNYDVDVAILQALLKASRSDEHAGRHCWERQLELAVAWNRVDIAESEIFTEESQWTSSDLHPAMFSALVGDKPEFVRLLLENGVCVREFLEREETLCELYSHLPSCFFLRKLAKRVQGGKMRRGQEPLPGSRKVCLSHVSEEVRHLLGSFTQPLYIASRYKPTKDDVRLKVPSKGALDLPCSGEEWSADTVWDPGRDLFLWAVVQNNRELAEIGWEQCRDCIAAALAASKILRKLAQESGEDDSEEATEMLELANHYEKQAIGVFSECHSWDAQRAQKLLIRISPSWGRSTCLWLALEAHDKSFIAHSGVQALLTQIWCGELSVDNPHWKVLLCMIFFPLIYTGFLTFRRDEDIQRQAERTEQQKLAMESVFAGQSDGKIKRHLRGFSQKSELKPLNCSSRLMSFLKSPQVKFYWNIASYFGFLWLFAVVLMIDFQ-TSPSWRELLLYVWLTSLVCEEIRQLYHDFDGSGFRRKAKMYIKDLWNILDVLSIVLFIAGLICRLQASDTVFYIGKVIL------CIDFII--FCLRLMAIFSISRTLGPKIIIVRRMMLDLFFFMFLLSIWVVAYGVAKQGILIENEERLNWIIRGAVYE-PYITIFGNFPTNIDNTLFDISSCSVNASDPLKPKCPMLNADNTPVFPEWLTIMMLCVYLLFANILLLNLLIAIFNYTFQEVQDNTDTIWKFQRYELIKEYHSRPALPPPF 1095
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. UniProt/SwissProt
Match: sp|A7T1N0|TMP2L_NEMVE (Transient receptor potential cation channel subfamily M member-like 2 OS=Nematostella vectensis OX=45351 GN=TRPM2 PE=1 SV=1) HSP 1 Score: 268.47 bits (685), Expect = 1.154e-71 Identity = 196/754 (25.99%), Postives = 365/754 (48.41%), Query Frame = 1
Query: 232 SNVH---FAENDEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGP-RESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYV-KNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKI------SQKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRS-DG--VAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSH--EDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSK--GLNDVKELLSKMIG--FYEYPCSEN-------------------------------DSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRD---TDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRA--GFNINFFSCILCIIFPFLISKRTEFTKD 2316
S+VH F N +++I F EC F ++ S+C CG ++ H + + G E W+ C PT ++G+I+F G K ++R+S+ + ++ L+ +W + L ISV GG F + + + +F +GLIKAA TT A IIT G N G+ +G+A++ Q + ++ +GIA WG V K +++ G+ HQ L+ NH+H+ DDG T+ K G R +E I S+ + +G+PVVLL++EGG + +K+KV VV +G+G+A+ ++G A+ H + R+ DG + ++ +++ ++ K++E + D+ I+D++++E +I+V+ + +D+D AIL +L+K +N++ +QL+L L WNR+D+ K IF+ + + + +A + +++ K +F ELFL+N ++++FL+ +IL +LY P +T + + +G+ K ++ V E++ +++G F Y + D + P+ ++FLWAVL +++ A+ W E + AL+A+R+ K + D TD S L FE AV +++EC + ++ ++ L+ ++ +++ ++ LELA + F+++ CQ + W N ++ ++C+ P LI F D
Sbjct: 16 SHVHLNKFGSNQLSQSKKSWIARNFSRRECIRFVPKSHDV----SRCKCGRPRERHSQQALESGQGSEEWNVASCTTKHPTNAYGEIDFEG--YGGQKRAPYLRMSHDTDANLVITLMLKRWNLEIPNLVISVTGGAKSFVLKPRLREMFRRGLIKAAKTTGAWIITGGTNTGVMKHVGEAVKEQQLMFGSDTQ----VNVIGIATWGIVDKQSDLISEKNGKYPALYSMEPTPGHQGAMLDPNHSHFFLVDDG-----TEGKYGVEIGMRSRIEEAIMKVKTDSRSEAGSIGVPVVLLVLEGGPNTVATMYELIKKKVPAVVIDGSGRAASVVGFAY--------NHTIKRNVDGQTINVIDPQYEDEVRAKVVE--VFGAKGADKTYSMIKDVLEDEKMISVYSLDGEISQDIDLAILKALLK-------ANRSSPVAQLNLALAWNRIDLAKSDIFTEEQQWTTETLSAAMLTALLDDKAEFAELFLQNGLSMREFLSLDILCKLYAEVPGNTTIKPLLQKEMGKRQVKTIDMDVVGEVIEELMGDMFESYYRKDGHYFGELASYAEGLVLKNRKSSKDLLANINRIDPLPTPYLDVFLWAVLCNRRELARVLWEAGREPMAAALMASRLLKRMASRAQEDNTITDISSDLYDHARLFEERAVGVLDECFNENETLSQTLLVRELDHYSRMTALELAVSAESQDFIAHTSCQVLLTRLWMGTMAMNTRWWKVLVCLYLPVLIFPIIYFVPD 737 HSP 2 Score: 87.4261 bits (215), Expect = 7.269e-16 Identity = 112/516 (21.71%), Postives = 242/516 (46.90%), Query Frame = 1
Query: 2344 PDFNED--------NCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLT-----IH--EIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQ-----RDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNSKLHIDKPMAFKHDTLNIFSNIKSDSDLNKLIKYFENYSQKFVIKNIAIEKQKSIKSGISRMEIRSKSIFKELENIQTKLNKIQIKNVKKVQEGSFTNTNGEYQNITKQPKDSMALLLTSLNNNILVLQDEVNRIGQEVNIVSTENSPVVIT 3831
P+ ED N + ++ FY AP +KF + +++FI ++YVVL+ R IH EI+ ++ +++++ ++ I ++ +++ + WN VD+ + I+A++LR+ +T+ + F S+ I SL + F ++ L++ + ++ LGPK+ M+ K++++L F I+ +F ++YG+ A +P R+ +W+ +++++ YPY+ M+G L + E P+ +L P+L A Y++ NILLLN+LIA +Y + + +S +WK+ Y L+ EY+ +P+ P +I + + ++ RC + +I +++ + +N+ +F + I +Q+ SG +E R +++ ++ I ++LN++ + ++ + + T+ NG + + +A + L++N LQ + + Q+ + P+ +T
Sbjct: 807 PEIREDDSMEVIMRNKKLGFCDRIMHFYSAPFSKFVGNVVGYLAFIFLYAYVVLFNFPRFDPAKTLGGIHPTEIVLYFWVFTILIEEIRQLAAKPPKYIKDKVSVYFS-DTWNFVDIFSLTVFIIAIILRF-------FTNSRI-FTASRIILSLDIIFFIVRSLQIFSVNRLLGPKLVMIQKMMQDLAQFIIILAVFTIAYGIALHAVMFPSPGIYARNNTWVTITSVVQYPYWQMYGEL------FLDEIQGEKPKEFGEVDPDGRWLSPLLLAIYMVFTNILLLNLLIAIFNYTFERVQEDSDKVWKFQRYDLVQEYHSRPVFAPPLVLLGHILIFIRWVWRMCRCGHPPRGSTMKIGLSPAEM-----------------------------EQMDNW--EFQAAEMYIHQQQQKNSGT--LEERVRALGDRVDCINSQLNRV-LDSMSGTRAHALTDGNGLEGGHDSEGR--LARMEVELSSNSESLQKILALLQQQPPVKGQAAVPIQLT 1271
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. UniProt/SwissProt
Match: sp|E9PTA2|TRPM2_RAT (Transient receptor potential cation channel subfamily M member 2 OS=Rattus norvegicus OX=10116 GN=Trpm2 PE=1 SV=3) HSP 1 Score: 252.292 bits (643), Expect = 1.287e-66 Identity = 286/1127 (25.38%), Postives = 503/1127 (44.63%), Query Frame = 1
Query: 160 TSQNEDYTVTIRQA---------RCKINESCRESNVHFAENDEKMQ-YRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKI-PYG-PRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQKQGDRVG----IPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISEL----------HQVDEAIKCIEDIIKNELLITVF--DIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSK----------GLNDVKELLSKMIG-----FYEYPCSEN-------------------------DSIKH------PFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN--FFSCILCII-FPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVL--MILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGY-YPQRDFSWIALSNILDYPYYTMFGVLNL---GNTVYFTWCNASTNYEVSNECPENN----------FLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDK 3252
+ Q E + V R+A R + C+ + + + EK + ++I K EC YF + K D C CG + H E I P+ + W + +PT +FG I FTG + K+ +VR+S I L+ W + +L ISV GG +F M + K+IF +GL+K A TT A IIT G + G+ +G+A++ L K + I+ +GIA WG + NR L G + +E + L+ NH+H+I DDG T + G R LE IS++ +R G IP+V +++EGG + V+ EG+G+ +D+I + VA LP S + LI+Q +S +Q+ E K I+DI++ L+TVF +D+D AIL +L+K QL L + WNRVDI + +IF+ + + + ++I+ K +F+ LFLEN +++F+T + L LYE S F +++ + ++ V ++L +++G Y P + S H P ++L +WA++ ++ A W + + AL ++I K + E L + FE+ A+ + EC+ D+E A L+ + +E WG +CL+LA ++ D+KF+S+ Q + W ++ + ILC++ FP L + F + K Q+ CR +++R F+ AP F ++ ++ +F+ F+YV+ M Q + ++IYL L ++ ++ ++F ++ + + WNK+D+ I+ I + R L +Y ++++ SL F L+++ + K LGPKI ++ +++K++ F ++ ++++S+GV QA + + WI ++ + Y T+FG + G C+ + +CPE++ +L L Y++ NILLLN+LIA +Y Q++ ++ IWK+ + LI EY+ +
Sbjct: 11 SDQEEGFGVQSRRATDLGMVPNLRRSNSSLCKSRRLLCSFSSEKQENLSSWIPENIKKKECVYFVESSKLSDAGKVVCECGYTHEQHIEVAIKPHTFQGKEWDPKKHVHEMPTDAFGDIVFTG---LSQKVGKYVRLSQDTSSIVIYQLMTQHWGLDVPSLLISVTGGAKNFNMKLRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVR--DFSLSSSCKEGDVIT-IGIATWGTIHNREALIHPMGGFPAEYMLDEEGQGNLTCLDSNHSHFILVDDG-----THGQYGVEIPLRTKLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIYNAITNGTPCVIVEGSGRVADVIAQ-------------------VAALPVSEITI---SLIQQKLSVFFQEMFETFTENQIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFTDEWQWKPSDLHPMMTAALISNKPEFVRLFLENGVRLKEFVTWDTLLCLYENLEPSCLFHSKLQKVLAEEHERLAYASETPRLQMHHVAQVLRELLGDSTQLLYPRPRYTDRPRLSLPMPHIKLNVQGVSLRSLYKRSTGHVTFTIDPVRDLLIWAIIQNHRELAGIIWAQSQDCTAAALACSKILKELSKEEEDTDSSEEMLAL-ADEFEHRAIGVFTECYRKDEERAQKLLVRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLCVDNGLWRIILCMLAFPLLFTGFISFRE--KRLQA---------LCRL---ARVRAFFNAPVVIFYLNILSYFAFLCLFAYVL---MVDFQPSPSWCEYLIYLWLFSLVCEETRQLFYDPDGCGLMKMASLYFSDFWNKLDVGAILLFIAGLTCR--LIPATLYPGRIIL--------SLDFIMFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNESRVDWI-FRGVIYHSYLTIFGQIPTYIDGVNFSMDQCSPNGTDPYKPKCPESDWTGQAPAFPEWLTVTLLCLYLLFANILLLNLLIAMFNYTFQEVQEHTDQIWKFQRHDLIEEYHGR 1075
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. UniProt/SwissProt
Match: sp|Q91YD4|TRPM2_MOUSE (Transient receptor potential cation channel subfamily M member 2 OS=Mus musculus OX=10090 GN=Trpm2 PE=1 SV=2) HSP 1 Score: 248.825 bits (634), Expect = 1.462e-65 Identity = 276/1074 (25.70%), Postives = 489/1074 (45.53%), Query Frame = 1
Query: 277 NYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKI-PYGPR-ESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVG----IPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISEL----------HQVDEAIKCIEDIIKNELLITVF--DIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGR----PFSKG-----LNDVKELLSKMIG-----FYEYPCSEND-----SIKH--------------------------PFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN--FFSCILCII-FPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVL--MILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGY-YPQRDFSWIALSNILDYPYYTMFGVLNL---GNTVYFTWCNASTNYEVSNECPENN----------FLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDK 3252
++I K EC YF + K D C+CG + H E I P+ + + W ++ +PT +FG I FT D++ K+ +VRVS I L+ W + L ISV GG +F M + K+IF +GL+K A TT A IIT G + G+ +G+A++ L K I+ +G+A WG + NR L G + +E + L+ NH+H+I DDG Q + R LE IS++ +R G IP+V +++EGG + V+ EG+G+ +D+I + VA LP S + LI+Q +S +Q+ E K I+DI++ L+T+F +D+D AIL +L+K QL L + WNRVDI + +IF+ + + + ++I+ K +F+ LFLEN +++F+T + L LYE S F +++ ++ ++ V ++L +++G Y P + ++ H P ++L +WAV+ ++ A W + + AL ++I K + E L + FE+ A+ + EC+ D+E A L+ + +E WG +CL+LA ++ D+KF+S+ Q + W ++ + ILC++ FP L + F + K Q+ CR +++R F+ AP F ++ ++ +F+ F+YV+ M Q + ++IYL L ++ ++ ++F ++ + + WNK+D+ I+ IV + R L +Y ++++ SL F L+++ + K LGPKI ++ +++K++ F ++ ++++S+GV QA + + WI ++ + Y T+FG + G C+ + +CPE++ +L L Y++ NILLLN+LIA +Y Q++ ++ IWK+ + LI EY+ +
Sbjct: 60 SWIPENIKKKECVYFVESSKLSDAGKVVCACGYTHEQHLEVAIKPHTFQGKEWDPKKHVQEMPTDAFGDIVFT--DLSQ-KVGKYVRVSQDTPSSVIYQLMTQHWGLDVPNLLISVTGGAKNFNMKLRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVR--DFSLSSSCKEGEVIT-IGVATWGTIHNREGLIHPMGGFPAEYMLDEEGQGNLTCLDSNHSHFILVDDGTHGQYGVEIP--LRTKLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIYNAINNGTPCVIVEGSGRVADVIAQ-------------------VATLPVSEITI---SLIQQKLSIFFQEMFETFTENQIVEWTKKIQDIVRRRQLLTIFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFTDEWQWKPADLHPMMTAALISNKPEFVRLFLENGVRLKEFVTWDTLLCLYENLEPSCLFHSKLQKVLAEEQRLAYASATPRLHMHHVAQVLRELLGDSTQLLYPRPRYTDRPRLSMTVPHIKLNVQGVSLRSLYKRSTGHVTFTIDPVRDLLIWAVIQNHRELAGIIWAQSQDCTAAALACSKILKELSKEEEDTDSSEEMLAL-ADEFEHRAIGVFTECYRKDEERAQKLLVRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLCVDNGLWRIILCMLAFPLLFTGFISFRE--KRLQAL---------CR---PARVRAFFNAPVVIFHMNILSYFAFLCLFAYVL---MVDFQPSPSWCEYLIYLWLFSLVCEETRQLFYDPDGCGLMKMASLYFSDFWNKLDVGAILLFIVGLTCR--LIPATLYPGRIIL--------SLDFIMFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNESRVDWI-FRGVVYHSYLTIFGQIPTYIDGVNFSMDQCSPNGTDPYKPKCPESDWTGQAPAFPEWLTVTLLCLYLLFANILLLNLLIAMFNYTFQEVQEHTDQIWKFQRHDLIEEYHGR 1074
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. UniProt/SwissProt
Match: sp|O94759|TRPM2_HUMAN (Transient receptor potential cation channel subfamily M member 2 OS=Homo sapiens OX=9606 GN=TRPM2 PE=1 SV=2) HSP 1 Score: 242.276 bits (617), Expect = 1.805e-63 Identity = 203/756 (26.85%), Postives = 337/756 (44.58%), Query Frame = 1
Query: 244 FAENDEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKI-PYGPRES-WSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQ-YSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVG----IPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQ----------VDEAIKCIEDIIKNELLITVF--DIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYE----TCPKSTNFRKTFLRLIGRPFSKG------LNDVKELLSKMIGFYEYPC----SENDSIK--------------------------------HPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN--FFSCILCII-FPFLISKRTEF 2307
F ND++ ++I K EC YF + K D C CG + H E P+ + + W ++ +PT +FG I FTG + K+ +VRVS I L+ W + L ISV GG +F M + K+IF +GL+K A TT A IIT G + G+ +G+A++ +S S Y K I+ +G+A WG V R L G + +E + L+ NH+H+I DDG Q + R LE IS++ +R G IP+V +++EGG VV EG+G+ +D+I + VA LP S + LI+Q +S Q + E K I+DI++ L+TVF +D+D AIL +L+K QL L + WNRVDI + +IF + + + ++I+ K +F++LFLEN +++F+T + L LYE +C + +K + RP ++ V ++L +++G + P ND ++ P ++L +WA++ +++ A W + + + AL ++I K + E L + Y E+ A+ + EC+ D+E A L+ + +E WG +CL+LA ++ D+KF+S+ Q + W +++ + LC++ FP L++ F
Sbjct: 50 FGNNDKQESLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEATKPHTFQGTQWDPKKHVQEMPTDAFGDIVFTG---LSQKVKKYVRVSQDTPSSVIYHLMTQHWGLDVPNLLISVTGGAKNFNMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSY---KEGELIT-IGVATWGTVHRREGLIHPTGSFPAEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIP--LRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIDNATTNGTPCVVVEGSGRVADVIAQ-------------------VANLPVSDITI---SLIQQKLSVFFQEMFETFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFMDEWQWKPSDLHPTMTAALISNKPEFVKLFLENGVQLKEFVTWDTLLYLYENLDPSCLFHSKLQKVLVEDPERPACAPAAPRLQMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQGVSLRSLYKRSSGHVTFTMDPIRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKEEEDTDSSEEMLALAEEY-EHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISF 773
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. TrEMBL
Match: A0A267FX17 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017231g3 PE=4 SV=1) HSP 1 Score: 543.502 bits (1399), Expect = 1.332e-165 Identity = 364/1066 (34.15%), Postives = 594/1066 (55.72%), Query Frame = 1
Query: 256 DEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKIT---AGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNIL----EFAKGR---TVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELH--QVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELY-ETCPKSTNFRKTFLRLIG------RPFSKGLNDVKELLSKMIGFYEYPCSEND--------SIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRT-SLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGF-----NINFFSCILCIIFPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFG--VLNLGNTVYFTWCNASTNYEVSNE-CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAF------CYQKGR 3327
+++ R +I A F+ EC F KC+CGE+++ H + +P GP E W+E M T ++G+I E N F RV D +D +++L+ W++ +LCISVIGG +FK+ ++K +F GLI+AA TTNA IIT GLN GIT V+G+A++ ++ ++K ++ + C+G+APWGYV NR+ L + G V Y +SN + K QP+SLN NHTHY+ DDG R + K G + L+ +I+QK+ GI VVLLIVEGG DIF E ++ + +V C+ TG+A+DII A++++Q+ + K + +A L E + L + +++ +VDE + + +I++ E LITVFD+ +DLD AIL +L+K MD + QL L +TWNR DI +KIF+ + + F +I K++F+ LFL+N +++FLT L+ LY E+ S+ +L+ P+ L D++ LL K++G + P + D + PF +LF WAVL+ KQ AKF W + DES+ LAL A+++Y R S + R L+ +K+ FE+LAV ++EEC +D A LIEKK E +G +CLELA+ + KF+S Q SI W G N+ F LC++ PFL+ EF + E +E ++ K+R +Y AP TKF ++ ++ FI +S+ +L+ MK ++ E + + ++ +M++++ E+F S++D + +++ WW F+ WN++D+ ++ A++ + LR A + + T +T Y L FYL++ RL + LGPK+ M+ K++KELL + +I+++ LL+YGV +QA YP RDF+ +I+ YPY+ ++G L + C + + S + CP ++ L+ +L A Y++++N+LL+N+LIA S I ++I NS+ IWK++MY L+ EY+ +P+L +PF +++ + F C +KG+
Sbjct: 75 EQQRSLRQFILANFQRKECCLFEAK------DGKKCACGEVREKH-DGLLPAGPEEKWNEATHMRRSVTNAYGRITLKNEGFDNRDPIHFARVCDEDSMDKMLELMKTHWQLADPQKPSLCISVIGGAKNFKLEGRKKEVFHHGLIRAAQTTNAWIITSGLNLGITRVVGNALEEGRASHWEKSSRSSKLRCIGVAPWGYVLNRDHLINKRDPKTGELSLDVEYKISNVISKGQPVSLNANHTHYLLVDDGKRNRYGGSKSGVIKAKLQEQINQKE----GISVVLLIVEGGLDIFEETQSMIQSNIPVVTCDNTGRAADIIAFAYKKVQK--ADKKTLSESQLADLRERMISTFSENLKDPKTKKVNDKKVDENMSMLLEIVQKEKLITVFDMNRSDDLDLAILSALLKVMDA---KRLDDYKQQLQLSMTWNRPDIAAEKIFTEEHQWGTENLDKFALSAISQEKIEFLRLFLKNGLIMREFLTVGRLRSLYRESLAASSQASLQVRKLLAARTRCRNPWEPTLADIRVLLRKLVGKFHAPSMDKDVGTGGDDEQFERPFNQLFFWAVLLCKQDTAKFLWERTDESVPLALAASKVYNEMARALSSHEDGRKRMLQAYKDEFEDLAVHVVEECQMVDPSKAELLIEKKVEAFGDFNCLELAASANCKKFVSCNSSQNSITSRWLNGLMHGTSNLRIF---LCVVLPFLLP--FEF-----LVRVEPSVRLDEGGRCAQLAHKVRIYYTAPVTKFFANAIWYVIFIFLYSWFILFEMKAASISWLEWVIIAWICVMVVEEIREMFSSKADTVQEKLRDWWGFSAWNRLDLFTMLLALIGIFLRIPEATDAITTG-------VRTCYILAGVLFYLRVFRLYYANSYLGPKLVMIQKMVKELLFYMSILIVALLTYGVAAQALLYPTRDFTTSIFVDIVYYPYWQIYGEIYLEVAEATPPEGCEDGSTVDSSGKLCPTHHSLVLLLLAVYLMVVNVLLINLLIAIFSNIFKEIQNNSVEIWKFNMYFLVHEYHTRPVLAVPFVIVEDVFRFIRFLACRLPCCRKGK 1107
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. TrEMBL
Match: A0A267E1J7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017231g2 PE=4 SV=1) HSP 1 Score: 542.347 bits (1396), Expect = 3.008e-165 Identity = 364/1066 (34.15%), Postives = 593/1066 (55.63%), Query Frame = 1
Query: 256 DEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKIT---AGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNIL----EFAKGR---TVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELH--QVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELY-ETCPKSTNFRKTFLRLIG------RPFSKGLNDVKELLSKMIGFYEYPCSEND--------SIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRT-SLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGF-----NINFFSCILCIIFPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFG--VLNLGNTVYFTWCNASTNYEVSNE-CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAF------CYQKGR 3327
+++ R +I A F+ EC F KC+CGE+++ H + +P GP E W+E M T ++G+I E N F RV D +D +++L+ W++ +LCISVIGG +FK+ ++K +F GLI+AA TTNA IIT GLN GIT V+G+A++ ++ ++K ++ + C+G+APWGYV NR+ L + G V Y +SN + K QP+SLN NHTHY+ DDG R + K G + L+ +I+QK+ GI VVLLIVEGG DIF E ++ + +V C+ TG+A+DII A++++Q+ + K + +A L E + L + +++ +VDE + + +I++ E LITVFD+ +DLD AIL +L+K MD + QL L +TWNR DI +KIF+ + + F +I K++F+ LFL+N +++FLT L+ LY E+ S+ +L+ P+ L D++ LL K++G + P + D + PF +LF WAVL+ KQ AKF W + DES+ LAL A+++Y R S + R L+ +K+ FE LAV ++EEC +D A LIEKK E +G +CLELA+ + KF+S Q SI W G N+ F LC++ PFL+ EF + E +E ++ K+R +Y AP TKF ++ ++ FI +S+ +L+ MK ++ E + + ++ +M++++ E+F S++D + +++ WW F+ WN++D+ ++ A++ + LR A + + T +T Y L FYL++ RL + LGPK+ M+ K++KELL + +I+++ LL+YGV +QA YP RDF+ +I+ YPY+ ++G L + C + + S + CP ++ L+ +L A Y++++N+LL+N+LIA S I ++I NS+ IWK++MY L+ EY+ +P+L +PF +++ + F C +KG+
Sbjct: 75 EQQRSLRQFILANFQRKECCLFEAK------DGKKCACGEVREKH-DGLLPAGPEEKWNEATHMRRSVTNAYGRITLKNEGFDNRDPIHFARVCDEDSMDKMLELMKTHWQLADPQKPSLCISVIGGAKNFKLEGRKKEVFHHGLIRAAQTTNAWIITSGLNLGITRVVGNALEEGRASHWEKSSRSSKLRCIGVAPWGYVLNRDHLINKRDPKTGELSLDVEYKISNVISKGQPVSLNANHTHYLLVDDGKRNRYGGSKSGVIKAKLQEQINQKE----GISVVLLIVEGGLDIFEETQSMIQSNIPVVTCDNTGRAADIIAFAYKKVQK--ADKKTLSESQLADLRERMISTFSENLKDPKTKKVNDKKVDENMSMLLEIVQKEKLITVFDMNRSDDLDLAILSALLKVMDA---KRLDDYKQQLQLSMTWNRPDIAAEKIFTEEHQWGTENLDKFALSAISQEKIEFLRLFLKNGLIMREFLTVGRLRSLYRESLAASSQASLQVRKLLAARTRCRNPWEPTLADIRVLLRKLVGKFHAPSMDKDVGTGGDDEQFERPFNQLFFWAVLLCKQDTAKFLWERTDESVPLALAASKVYNEMARALSSHEDGRKRMLQAYKDEFEELAVHVVEECQMVDPSKAELLIEKKVEAFGDFNCLELAASANCKKFVSCNSSQNSITSRWLNGLMHGTSNLRIF---LCVVLPFLLP--FEF-----LVRVEPSVRLDEGGRCAQLAHKVRIYYTAPVTKFFANAIWYVIFIFLYSWFILFEMKAASISWLEWVIIAWICVMVVEEIREMFSSKADTVQEKLRDWWGFSAWNRLDLFTMLLALIGIFLRIPEATDAITTG-------VRTCYILAGVLFYLRVFRLYYANSYLGPKLVMIQKMVKELLFYMSILIVALLTYGVAAQALLYPTRDFTTSIFVDIVYYPYWQIYGEIYLEVAEATPPEGCEDGSTVDSSGKLCPTHHSLVLLLLAVYLMVVNVLLINLLIAIFSNIFKEIQNNSVEIWKFNMYFLVHEYHTRPVLAVPFVIVEDVFRFIRFLACRLPCCRKGK 1107
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. TrEMBL
Match: A0A267FD75 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017231g1 PE=4 SV=1) HSP 1 Score: 541.962 bits (1395), Expect = 5.413e-165 Identity = 363/1066 (34.05%), Postives = 592/1066 (55.53%), Query Frame = 1
Query: 256 DEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKIT---AGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAK-------GRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELH--QVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELY-ETCPKSTNFRKTFLRLIG------RPFSKGLNDVKELLSKMIGFYEYPCSEND--------SIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRT-SLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGF-----NINFFSCILCIIFPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFG--VLNLGNTVYFTWCNASTNYEVSNE-CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAF------CYQKGR 3327
+++ R +I A F+ EC F KC+CGE+++ H + +P GP E W+E M T ++G+I E N F RV D +D +++L+ W++ +LCISVIGG +FK+ ++K +F GLI+AA TTNA IIT GLN GIT V+G+A++ ++ ++K ++ + C+G+APWGYV NR+ L + V Y +SN + K QP+SLN NHTHY+ DDG R + K G + L+ +I+QK+ GI VVLLIVEGG DIF E ++ + +V C+ TG+A+DII A++++Q+ + K + +A L E + L + +++ +VDE + + +I++ E LITVFD+ +DLD AIL +L+K MD + QL L +TWNR DI +KIF+ + + F +I K++F+ LFL+N +++FLT L+ LY E+ S+ +L+ P+ L D++ LL K++G + P + D + PF +LF WAVL+ KQ AKF W + DES+ LAL A+++Y R S + R L+ +K+ FE LAV ++EEC +D A LIEKK E +G +CLELA+ + KF+S Q SI W G N+ F LC++ PFL+ EF + E +E ++ K+R +Y AP TKF ++ ++ FI +S+ +L+ MK ++ E + + ++ +M++++ E+F S++D + +++ WW F+ WN++D+ ++ A++ + LR A + + T +T Y L FYL++ RL + LGPK+ M+ K++KELL + +I+++ LL+YGV +QA YP RDF+ +I+ YPY+ ++G L + C + + S + CP ++ L+ +L A Y++++N+LL+N+LIA S I ++I NS+ IWK++MY L+ EY+ +P+L +PF +++ + F C +KG+
Sbjct: 75 EQQRSLRQFILANFQRKECCLFEAK------DGKKCACGEVREKH-DGLLPAGPEEKWNEATHMRRSVTNAYGRITLKNEGFDNRDPIHFARVCDEDSMDKMLELMKTHWQLADPQKPSLCISVIGGAKNFKLEGRKKEVFHHGLIRAAQTTNAWIITSGLNLGITRVVGNALEEGRASHWEKSSRSSKLRCIGVAPWGYVLNRDHLINKRDPKIGELSLDVEYKISNVISKGQPVSLNANHTHYLLVDDGKRNRYGGSKSGVIKAKLQEQINQKE----GISVVLLIVEGGLDIFEETQSMIQSNIPVVTCDNTGRAADIIAFAYKKVQK--ADKKTLSESQLADLRERMISTFSDNLKDPKTKKVNDKKVDENMSMLLEIVQKEKLITVFDMNRSDDLDLAILSALLKVMDA---KRLDDYKQQLQLSMTWNRPDIAAEKIFTEEHQWGTENLDKFALSAISQEKIEFLRLFLKNGLIMREFLTVGRLRSLYRESLAASSQASLQVRKLLAARTRCRNPWEPTLADIRVLLRKLVGKFHAPSMDKDVGTGGDDEQFERPFNQLFFWAVLLCKQDTAKFLWERTDESVPLALAASKVYNEMARALSSHEDGRKRMLQAYKDEFEELAVHVVEECQMVDPSKAELLIEKKVEAFGDFNCLELAASANCKKFVSCNSSQNSITSRWLNGLMHGTSNLRIF---LCVVLPFLLP--FEF-----LVRVEPSVRLDEGGRCAQLAHKVRIYYTAPVTKFFANAIWYVIFIFLYSWFILFEMKAASISWLEWVIIAWICVMVVEEIREMFSSKADTVQEKLRDWWGFSAWNRLDLFTMLLALIGIFLRIPEATDAITTG-------VRTCYILAGVLFYLRVFRLYYANSYLGPKLVMIQKMVKELLFYMSILIVALLTYGVAAQALLYPTRDFTTSIFVDIVYYPYWQIYGEIYLEVAEATPPEGCEDGSTVDSSGKLCPTHHSLVLLLLAVYLMVVNVLLINLLIAIFSNIFKEIQNNSVEIWKFNMYFLVHEYHTRPVLAVPFVIVEDVFRFIRFLACRLPCCRKGK 1107
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. TrEMBL
Match: A0A4E0RDV5 (Transient receptor potential cation channel subfamily M member 6 OS=Fasciola hepatica OX=6192 GN=D915_004383 PE=4 SV=1) HSP 1 Score: 517.309 bits (1331), Expect = 1.307e-156 Identity = 376/1098 (34.24%), Postives = 588/1098 (53.55%), Query Frame = 1
Query: 361 CSCGEIKKSHKENKIPYGP-------RESWSEGDCMEML-PTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKI---TAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAK-GRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKIS-QKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKL--IEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELY---------ETCPKSTNFRKTF--------------------LRLIGRPFSKG---------LNDVKELLSKMIGFYEYPCSEND-----------------SIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLE--TWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN--FFSCILCIIFPFLISKRTEFTKDFKTCQS---------------ESFP------------DF-----NEDNCRTSISSKLRR----FYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRD-FSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQK 3321
C CGE +K H + P WSE ++ + PT +FG+IEF E T+ + +FVR+S RD+L D++ L+ + W + +LCISVIGG +F + + K++F GLI+AA TTNA I+T GLN GI V+GDA+Q Q++ +D+ + +N + CLGI+PWGYV NRN L+ + V Y VSN +E +P+SLN+NHTHYIF D+G RL+ FR L +++ +Q GIPVVL++VEGGHD+FI+A ++E++ +V+C GTG+ASD++ AF R K + D PE +NVL + L I +D E A++ I +II++ LIT+F++ +DLD AIL++LIK + +++QL L TW+R DI ++K+F + + + + +++ K +F+ + L+N ++ FLT L LY E C RK+ RL + G L+ V L+ KMIG + + E D + PF ELFLWAVL +Q+ A FFW + D S+ LA++A +Y + SL + D LE T + FE LAV+L+EEC+ +D E+ YL+E + WGG +CL LA K+T KF+S++ CQ S+ + W G + F+ L L + EF D T S +S P DF N S LRR Y AP+TKF +++ +I+F+++FSY +L+ + ++T+ E + M Y V +++D +I + Y +++ W N +D+I I+ A+V++ LR + ++G +T +KT+YSL + Y++I RL H LGPK+ M+ ++I EL +F I+ + L+SYGV+ QA +P R F W + ++L YPY+ ++G LNL + F + T+ CP+ NF++P+L A Y+++ ILL+N+LIA S + Q + NSI +WK++MY L++EYN +P++P+PFS + +V F +K
Sbjct: 9 CFCGEYEKGHAKYFTSNEPSINSKFENLPWSENTHLQYIKPTEAFGQIEFLTETATSQRPAEFVRISDRDELKDVMVLMEDYWHMMEPAKPSLCISVIGGAKNFVLEGRRKDVFNTGLIQAAQTTNAWIVTSGLNLGIVRVVGDALQEGQTWHFDRRRLSNKLRCLGISPWGYVLNRNELKCDNYDKPVLYRVSNVIETGRPVSLNENHTHYIFVDEGRRLRYGGSASATFRARLGKQMALPEQAGGWGIPVVLVVVEGGHDVFIDARDCIRERIPVVICCGTGRASDLMNLAF------TYRMKQPKHDFKDFRPEE-RNVLLQALTPISRDEKE-----SALEMIIEIIQDPKLITIFNMNQSDDLDLAILFALIK--------TNSQITTQLELAFTWDRSDIAEEKVFRQGVRVGPESLEPIMMKALLRDKPEFVRILLQNGIVMRQFLTVERLSLLYNKSIHRNAFERCLSQKGLRKSIKQKTSARKVAPQQQMDVQLGTRLTRVTTTPGDTLEVAPVYLSTVSRLVRKMIGRFLHKTYEQDTQELRRYKNNWNRFRNYTFDSPFHELFLWAVLHHRQRMAMFFWERADNSIALAMIACALYADMIK-SLPNYDTETQLEYVTHMDEFERLAVQLLEECYTMDPEITLYLVEHEAPLWGGYNCLNLADKATRRKFISSVACQNSLFYAWSHGTQASPLSFTLTLFCPLLLLSDRFVEFNDDRGTEMSLDQVNDKDSSESWHHDSSPSNPNNRERNNEIDFVPRRINPTEGSKPPSLPLRRKLLVLYTAPRTKFFLNTIAYIAFLLFFSYTLLFKISSNEITVEEALTMTYFVSLLVDIIRQICVTPGAGSY-KLRLWVKINSLVYLDIIGILLALVSIFLR--IGLSGTFTA-------AKTLYSLTLIICYMRIFRLYGFHPALGPKLVMIQRMIAELFLFLLILAVILISYGVSMQALLFPNRTIFDWNTIRDVLYYPYFNLYGELNLDYS--FAIKDNCTSDADGVTCPQYNFMVPLLLAIYLMLAGILLINLLIAIFSNVFQQVEDNSIELWKFNMYGLVVEYNRRPVIPVPFSIIQAVVEVFQFLIKK 1073
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. TrEMBL
Match: G4VFC6 (Putative transient receptor potential cation channel,subfamily m, member OS=Schistosoma mansoni OX=6183 GN=Smp_165170 PE=4 SV=1) HSP 1 Score: 512.686 bits (1319), Expect = 2.442e-156 Identity = 371/1084 (34.23%), Postives = 586/1084 (54.06%), Query Frame = 1
Query: 277 NYINAKFKSVECRYFSVAIKEIDDKNS--KCSCGEIKKSHK--ENKIPYGPRESWSEGDCMEML-PTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAG---TLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRT-VHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKIS---QKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISEL-HQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYET---------CPKSTNFRKTFLRLIGRPFSKGLND----------VKELLSKMIG-----FYEYPCSENDSIKH---------PFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYH-QRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINFFSCILCIIFPFLISKRTEF-----------TKDFKTCQSESFPDF-NEDNCRTS-----------ISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQR-DFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSN-ECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFC 3312
N+I FK EC F + + +C CGE+ H EN I +W+E + ++++ PT +FG+IEF+ I K T+FVR+S D+L+D++ L+ + WK+ +LCISVIGG F + +K++F GL++AA++T A I+T GLN GI ++G A+Q Q + +D+ K + + CLGIAPWGYV NR L T + Y +++ + + P+SLN+NHTHYIF D+G RL+ K FR LE +I+ +K G GIPVVL+IVEGGHD+FI+A +KE V +V+C GTG+A+DI+ AF +++D E+ VLK+KL Q+IS +VD AIK IE I++NE LIT FD+ DLD AIL+SLIK + QL L W R DI ++KIF F+ +++ ++ F++LFL + +++ FLT + L LY C + + ++ + D V LL KM+G YE D++ + PFQELFLWAVL ++Q A +FW D L LAL+ +Y + DT+ E++ FE +A +L+E+C+ +E+ L++++ WG +CL LA++S KF+S+ CQ S+ WR G + N F + + FPFL+ F +++ + S PD N+ N T I S+ + FY AP+TKF ++ ++ F+I+FSY +L+ +++IHE + + Y + ++D +I +S+ +G + W +WNK D++++ + + +LR + F +K+ Y + + YLK+ L + H +LGPK+ M+ ++ ELL+F I+++ L+SYGV+ Q YP R DFSW L +IL YPY+ ++G + L F +A T V N ECP +N+L P+ A Y++I ILL+N+LIA S + + I NSI +WK++++S++LEY+ +P+LP+PFS+ I + + +C
Sbjct: 35 NFILRCFKYKECVKFVPDPTKPQRPHGHLQCYCGELDYKHHDYENMIKNNNDNTWTESNDIKIIGPTNAFGQIEFSDSPI--QKPTEFVRISDEDRLEDVMILMKDYWKMMEPEKPSLCISVIGGAKSFVLDGHKKDVFYSGLVQAALSTKAWIVTSGLNLGIVRMVGKALQ-DQKFHFDEWKPSESLICLGIAPWGYVLNRQTLISEDHNTPIRYEITDFITRDSPVSLNQNHTHYIFVDEGRRLRYGGSKSAEFRARLEKQIALPVEKGG--FGIPVVLVIVEGGHDVFIDARNSLKEHVPVVICSGTGRAADILTLAF---------EYRLKNDTFNGFSETELAVLKQKL--QNISGTPSKVDSAIKMIEFIVQNESLITTFDMNQSNDLDLAILFSLIK--------TSSNADKQLELAFAWKRSDIAREKIFQQGYQFDQVTLEYFMLEALKKDELDFVKLFLHHGVSMKAFLTVDRLSTLYNNSVHRDGLIKCLRKHKLLQLSTNIVKNENASQFTDTSNKKLRLATVGLLLDKMLGGFDNYLYETDADSPDNLPNVVNRSRFSSPFQELFLWAVLHQRQHMALYFWELSDNGLILALIGCCLYSNMIKLLPSYDTEARTLYESYVKEFEMIATRLLEKCYATSEELTLNLLDRETYIWGNFNCLSLAAQSLRRKFISSTACQDSLYRAWRGGVHTNAFVILATLFFPFLLCFDCLFRWDNRRAIENESQNLVESINSSNPDIRNKRNNSTDSCCGIIPKCKKIKSRFQLFYTAPRTKFIFNALVYVVFLIHFSYTLLFQTLPDKISIHESIVIGYFIAKLIDMIEQISQSQ----FGLLSAQWRDLYWNKSDVVLVCLGLFSALLRIGFSKT---------FILAKSFYVITLVGCYLKVYSLYSHHPRLGPKLVMIRSMLIELLMFIFILVVVLVSYGVSQQVLLYPYRADFSWRTLRDILYYPYWNLYGEIMLEYA--FAESDACTLTGVLNSECPMSNYLSPLFLAIYLMIAGILLINLLIAIFSNVFEKIEENSIELWKFNIFSIVLEYSSRPVLPVPFSSITAIIKFILYC 1079
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Cavefish
Match: trpm5 (transient receptor potential cation channel subfamily M member 5 [Source:NCBI gene;Acc:103047602]) HSP 1 Score: 235.728 bits (600), Expect = 1.029e-62 Identity = 278/1148 (24.22%), Postives = 513/1148 (44.69%), Query Frame = 1
Query: 469 FGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQ-YSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVG-----IPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVD--EAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXX---XXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFL-------------RLIGRPFSKG--------LNDVKELLSKMI-----GFYEYPCSE-----------------NDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINFFSCILCIIF---PFLISKRTEFTKDFKTCQS---------------------------ESFPDFNEDNCRTSISS----KLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQ---LTIHEIMFMIYLVLMILDKFVEIFKSRSD-RIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVV-MFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRD-FSWIALSNILDYPYYTMFGVLNLG--NTVYFTWCNASTNYE-----VSNECPE--NNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNSKL-HIDKPMAFKHDT-LNIFSNIKSDSDLNKL-IKYFENYSQKFVIKNIAIEKQKSIKSGISRMEIRSKSIFKEL 3594
G I+F G T K F RVS I L+ +W ++ L ++++GG +M ++ +GL++A +T A I+T GL GIT +G A++ +S + K++ + +GIAPW + N+ +L AK + ++ SL+ +H+H+I ++ Q G R L IS ++ G IPV+ L+V G I + ++ ++ G+G +DI+ + R C +M++ +L E+F LH D +K I+ I++N L+TV D + DLD IL +L+K C S +L L + WNRVDI K +IF+GD+ S + + D+++ K F+ LF++N N+ +FLT L+ELY + + + L R G P+ + L++V ++L + GFY+ +E + ++P+++LFLWAVL +QK A +FW E++ AL +I K + + + +++ K +E A+ L EC+ ++ A L+ +K W + L LA+++ F ++ Q + W + L + F P + + +F+ + + E+ D + +C + S + +RF+ AP T F + + +F++ F+YV+L + +I EI+ ++ ++L++ + F + D I + K + ++WNK ++ L + GV + + +T+ +L F L+++ + A HK+LGPKI ++ +++K++ F + ++L++YGV +QA +P W+ +L PY +FG + L + N + + + CP N+L+ +L Y+++ N+LLLN+LIA SY Q + GN+ + WK+ Y+LI+EY+ +P L PF ++ Q+L LS KK E SK+ H+++ + D L + ++ ++ L +L ++ E+ ++ + ++ I GI E R S+ E+
Sbjct: 68 LGDIDFIGSSRTRGK---FARVSSMTDPVLIYQLLTEQWGLSPPHLVVALVGGDELDQMKPWLRDTVRKGLVRATQSTGAWILTNGLQFGITKHLGQAVRDHSLASTSSKVR----VVAIGIAPWTMIHNKEMLLTAKPDQPAAYPTEDLPHGSVYSLDCHHSHFILVEEE---QHRSGATGDMRVKLLKHISLQRTGYGGPGSFEIPVLCLLVHGEPKILQRMYKTIQNATPWLLLAGSGGVADIL---VTLIYRGCWDTEMVQE----LLLETFTG-------------LHSTDITSWVKVIQKILENGHLLTVHDPEQTADLDTVILKALVKA----CKSQSQEAQDFLDELKLAVAWNRVDIAKSEIFNGDVEWSPQDLEEVMMDALVNDKPDFVRLFVDNGVNLGEFLTYGRLQELYCSVSEKSLLFDLLLKKHQEKQMLLASARTPGPPYMEPVDRRPRFTLHEVSKVLKDFLHDSCKGFYQKLPAERVGKGRLFHSQKDLPDLDQHCENPWRDLFLWAVLQNRQKMANYFWAMGPEAVAAALAGCKILKEMAHLE-SEAESARSMKEAK--YEQFALDLFSECYSNSEDRAYALLVRKTHCWSKSTVLNLATEADAKSFFAHDGVQALLTKIWWGAMTTDTSISKLVLSFFCPPLIWTNLIKFSDEILQSRGGGEQFAELDSLDTEKALLLSDDDPDDSEAAGDPADQSCSQAWSQFLLRRWKRFWSAPVTVFLGNVLMYFAFLVLFTYVLLLDFRPPPPDGPSIAEIILYFWVFTLVLEEIRQSFFTDEDMNILKKCKL-YVEDNWNK-----------CDMVAISLFVVGVSCRMMENTYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLIAYGVATQALLHPNDPRLDWV-FRRVLYRPYLHIFGQIPLEEIDAAKMQPDNCTMDLQDIITGTLPPCPNIYANWLVILLLVIYLLVTNVLLLNLLIAMFSYTFQVVQGNTDIFWKFQRYNLIVEYHSRPALAPPFIIISHLSQIL-----------LSLCKKSE-----SKIEHLERELPAGLDQKLMTWETVQKENYLARLERRHLESSEERLKSTSSKVQSLLQIVGGIKDQEKRMASMEAEV 1149
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Cavefish
Match: hrc (transient receptor potential cation channel subfamily M member 4-like [Source:NCBI gene;Acc:103047479]) HSP 1 Score: 213.772 bits (543), Expect = 9.546e-56 Identity = 177/704 (25.14%), Postives = 329/704 (46.73%), Query Frame = 1
Query: 361 CSCGEIKKSHK----ENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQ-YSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGR-TVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVG--YFRQALENKISQKQGDRVG-----IPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQ---VDEAIKCIEDIIKNELLITVFDIKSH--EDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLI---------GRPF---SKGLN--DVKELLSKMIG-----FYEYP------CSENDSIKH-----------------PFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINF--FSCILCIIFPFL 2286
C CG + SH + W PT +FG++EF G + + ++F+R+S ++ + W + L +SV+GG K+ K + + QGL++AA +T A I++ GL +GI +G+A++ ++ + D + + +G+APWG V R+ L +G Y V+N L+ NH ++ DDG T ++ G FR LEN ISQ++ ++G IPV+ +V G + +K+ + +V G+G +D++ + ++ + + + + K L+ ++ E+ + VD+ + + ++ K++ LI+++ ++ ED D +L +L++ S+ + + +L L +TWNRVDI + ++F+GDI N+ +F+ D+++ K +F+ LF+EN N+Q+++T L+ELY + S+ R + G P +KGL +V +LL ++G FY+ S +IK P+ LF WAVL + + A FFW ES+ AL A ++ + + +T+ +L+ FENLA + +C+ + + L++KK+ W G +CL++A ++ F S+ Q + W + N + +L + P L
Sbjct: 50 CQCGGSRDSHATVSLNDYFSSAIVSHWDSALHSSEAPTDAFGEVEFGG---VSKRHSNFLRLSSDTPPATAYTILTSNWGLPKPNLVLSVVGGVGRSKVKPKLREVLRQGLVRAAQSTGAWILSGGLREGIDRCLGEAVRDHTTAASSDSLTK---VVAIGVAPWGLVNLRDELVNPEGSYPAGYFVTNT--SRDSYCLDTNHQAFLLVDDGS----TGRRGGEARFRAGLENYISQQRTGKLGSGSMDIPVLCTLVSGELYMLERLDLSLKKCIPWMVLAGSGGLADLVTDV---LENVAAAPVLPAGGAEGEGEATTKINLRERVAEKVVKHFPSEPDVDKLVDKLLNVHKSQDLISIYHLEQEGPEDFDTVLLKALVRASKQRLSSDASLSTEELKLAVTWNRVDIARSELFTGDIQWKNESLESFMTDALVNDKPQFVRLFIENGLNVQEYMTFGRLEELYRSISDSSVAYTLLQRHLSERQGVAGTGWPAADPAKGLTLYEVAQLLEDLLGDVCQPFYDDKLKIQGITSRRKTIKKLTTVLQEGEYRQQRCVFPWASLFTWAVLQNRSEMAVFFWEMTPESVLSALSACKLLRELCKLE-NETETKHSLKELAMKFENLAHDVFSKCYQSSESRSFVLLKKKSVVWRGATCLQMAMEADARHFFSHDGVQTLLSQIWWGDMDRNTENWKLVLTLFIPPL 737 HSP 2 Score: 66.6254 bits (161), Expect = 1.791e-10 Identity = 56/184 (30.43%), Postives = 98/184 (53.26%), Query Frame = 1
Query: 2776 FYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNT-VYFTW-CNASTNYEVSNECPEN------NFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVL 3303
F L+++ + A HK+LGPKI ++ K++K++ F + +++++YGV +Q Y + L + PY +FG + F W +TN +E E N+++ IL Y+++ NILL+N+LIA SY + S V WK+ + +I+EY+ +P L PF F + +Q +
Sbjct: 933 FTLRLIHIFAIHKQLGPKIIIVGKMMKDVFFFLFFLAVWMMAYGVANQGLIYSFDPSADRILRRVFYRPYLHIFGQIPYEQMDSGFEWNVTCTTNVTEIDENMEPCRDTRYNWMVVILLMIYLLVTNILLINLLIAMFSYTFTKVQERSDVYWKFQRFKVIIEYHSRPCLAPPFIIFSHFHQFI 1116
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571]) HSP 1 Score: 214.157 bits (544), Expect = 1.591e-55 Identity = 167/523 (31.93%), Postives = 261/523 (49.90%), Query Frame = 1
Query: 265 MQYRNYINAKFKSVECRYFSVAIK---------EIDDKNSKCSCGEIKKSH---------KENKIPYG----PRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPIS----LNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDIFIEASRRVKE--KVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTN 1725
M +++I + F EC Y K +I + +C CG + + H K + + G P E WS + E PT ++G I F G ++S +VR+S+ + + I+ L+ +W++ + ISV GG +F +H + K + +GLIKAA+TT A I+T G+N G+ +GDA++ S K I +GIAPWG ++NRN L GR V V+ P+S LN H+H+I D+G T K G R+ LE I+ Q+ R+ G+PVV LI EGG ++ + ++E V +VVCEGTG+A+DI+ ++ + + +D +A + ++F L + D L Q + + +KN+ LITVF + S H+D+D AIL +L+K D QL L L W+RVDI KD +F L D + D+++ +V F++L +EN ++ FLT + L+ELY T TN
Sbjct: 1 MSQKSWIESTFTKRECVYILPVSKDPHRCLPGCQICQQLVRCCCGRLVRQHVGFTASLAMKYSDMKLGEAQPPHEEWSVENHTEQSPTDAYGIINFQGG--SHSYRAKYVRLSHDSRPEAILRLMLKEWQMELPKIVISVHGGIQNFDLHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHSSRSARK------ICTIGIAPWGVIENRNDL---IGRDV---VAPYQTLLNPLSKLNVLNNLHSHFILVDNG-----TVGKYGAEVNLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTEDDGGLPDGVETDIIATVKKTF------NLSQNDAVHLFQT------LMECMKNKELITVFHVGSEDHQDIDVAILKALLKGTD-------ASAFDQLVLTLAWDRVDIAKDHVFVYGQKLLVDSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTISRLEELYNTKQSPTN 485 HSP 2 Score: 157.147 bits (396), Expect = 4.744e-38 Identity = 155/566 (27.39%), Postives = 265/566 (46.82%), Query Frame = 1
Query: 1834 ENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYK---YHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNI---NFFSCILCIIFPFLI-----SKRTEFTKDFKTCQSESF-----------PD------FNEDNC-----------------RTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVY---FTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNSKLH 3387
E +PF EL +WAVLM++QK + FFW +ES+ ALVA ++ + Y + S D SE L+ + N F LAV L+E+ D+ ++ L+ + +NW +CL+LA S F+++ Q + W N+ +++ IL I+ P I + E ++ + PD F E R I K FY AP KF ++ ++ F++ +SYVVL + + E ++Y+ ++K E+F S +I +IK W++ +++N+ D I IV V LR+ +F + IY L + +Y+++L +LA +++ GP + M+ K++ + I+ + L++YGV +A YP + W + +++ PY+ M+G VY C ST + + C +L P L A Y+ I IL++N+LIA + + + S ++WKY Y I+ Y+DKP+LP P F +I L+F ++ + + K F + KLH
Sbjct: 611 ETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVVDDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYKVILSILVPPAILALEYKSKAEMAHIPQSQDAHQMTMEDSEHNLQNPDDIQMDVFKETRINDHVEVKHETEVVTRSRRLPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKLPIFP-SPQEWAVILYIFTSAIEKIREMFMSEGGKISQKIKVWFS-DYFNRSDFIAIVMFAVGFGLRFGSG---------NVFIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYG------EVYAYEIDVCANSTENNMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIFYHISSFLSFLCKRRKKDSAYGPKLFLTEEDQKKLH 1159
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571]) HSP 1 Score: 213.772 bits (543), Expect = 1.837e-55 Identity = 167/523 (31.93%), Postives = 261/523 (49.90%), Query Frame = 1
Query: 265 MQYRNYINAKFKSVECRYFSVAIK---------EIDDKNSKCSCGEIKKSH---------KENKIPYG----PRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPIS----LNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDIFIEASRRVKE--KVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTN 1725
M +++I + F EC Y K +I + +C CG + + H K + + G P E WS + E PT ++G I F G ++S +VR+S+ + + I+ L+ +W++ + ISV GG +F +H + K + +GLIKAA+TT A I+T G+N G+ +GDA++ S K I +GIAPWG ++NRN L GR V V+ P+S LN H+H+I D+G T K G R+ LE I+ Q+ R+ G+PVV LI EGG ++ + ++E V +VVCEGTG+A+DI+ ++ + + +D +A + ++F L + D L Q + + +KN+ LITVF + S H+D+D AIL +L+K D QL L L W+RVDI KD +F L D + D+++ +V F++L +EN ++ FLT + L+ELY T TN
Sbjct: 1 MSQKSWIESTFTKRECVYILPVSKDPHRCLPGCQICQQLVRCCCGRLVRQHVGFTASLAMKYSDMKLGEAQPPHEEWSVENHTEQSPTDAYGIINFQGG--SHSYRAKYVRLSHDSRPEAILRLMLKEWQMELPKIVISVHGGIQNFDLHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHSSRSARK------ICTIGIAPWGVIENRNDL---IGRDV---VAPYQTLLNPLSKLNVLNNLHSHFILVDNG-----TVGKYGAEVNLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTEDDGGLPDGVETDIIATVKKTF------NLSQNDAVHLFQT------LMECMKNKELITVFHVGSEDHQDIDVAILKALLKGTD-------ASAFDQLVLTLAWDRVDIAKDHVFVYGQKLLVDSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTISRLEELYNTKQSPTN 485 HSP 2 Score: 157.147 bits (396), Expect = 4.757e-38 Identity = 155/566 (27.39%), Postives = 265/566 (46.82%), Query Frame = 1
Query: 1834 ENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYK---YHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNI---NFFSCILCIIFPFLI-----SKRTEFTKDFKTCQSESF-----------PD------FNEDNC-----------------RTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVY---FTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNSKLH 3387
E +PF EL +WAVLM++QK + FFW +ES+ ALVA ++ + Y + S D SE L+ + N F LAV L+E+ D+ ++ L+ + +NW +CL+LA S F+++ Q + W N+ +++ IL I+ P I + E ++ + PD F E R I K FY AP KF ++ ++ F++ +SYVVL + + E ++Y+ ++K E+F S +I +IK W++ +++N+ D I IV V LR+ +F + IY L + +Y+++L +LA +++ GP + M+ K++ + I+ + L++YGV +A YP + W + +++ PY+ M+G VY C ST + + C +L P L A Y+ I IL++N+LIA + + + S ++WKY Y I+ Y+DKP+LP P F +I L+F ++ + + K F + KLH
Sbjct: 611 ETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVVDDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYKVILSILVPPAILALEYKSKAEMAHIPQSQDAHQMTMEDSEHNLQNPDDIQMDVFKETRINDHVEVKHETEVVTRSRRLPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKLPIFP-SPQEWAVILYIFTSAIEKIREMFMSEGGKISQKIKVWFS-DYFNRSDFIAIVMFAVGFGLRFGSG---------NVFIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYG------EVYAYEIDVCANSTENNMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIFYHISSFLSFLCKRRKKDSAYGPKLFLTEEDQKKLH 1159
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571]) HSP 1 Score: 213.386 bits (542), Expect = 2.568e-55 Identity = 164/504 (32.54%), Postives = 253/504 (50.20%), Query Frame = 1
Query: 295 FKSVECRYFSVAIKEIDDKNSKCSCGEIKKSH---------KENKIPYG----PRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPIS----LNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDIFIEASRRVKE--KVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTN 1725
F EC Y I + +C CG + + H K + + G P E WS + E PT ++G I F G ++S +VR+S+ + + I+ L+ +W++ + ISV GG +F +H + K + +GLIKAA+TT A I+T G+N G+ +GDA++ S K I +GIAPWG ++NRN L GR V V+ P+S LN H+H+I D+G T K G R+ LE I+ Q+ R+ G+PVV LI EGG ++ + ++E V +VVCEGTG+A+DI+ ++ + + +D +A + ++F L + D L Q + + +KN+ LITVF + S H+D+D AIL +L+K D QL L L W+RVDI KD +F L D + D+++ +V F++L +EN ++ FLT + L+ELY T TN
Sbjct: 3 FTKRECVY----ILPVSKDPHRCCCGRLVRQHVGFTASLAMKYSDMKLGEAQPPHEEWSVENHTEQSPTDAYGIINFQGG--SHSYRAKYVRLSHDSRPEAILRLMLKEWQMELPKIVISVHGGIQNFDLHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHSSRSARK------ICTIGIAPWGVIENRNDL---IGRDV---VAPYQTLLNPLSKLNVLNNLHSHFILVDNG-----TVGKYGAEVNLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTEDDGGLPDGVETDIIATVKKTF------NLSQNDAVHLFQT------LMECMKNKELITVFHVGSEDHQDIDVAILKALLKGTD-------ASAFDQLVLTLAWDRVDIAKDHVFVYGQKLLVDSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTISRLEELYNTKQSPTN 464 HSP 2 Score: 158.303 bits (399), Expect = 1.997e-38 Identity = 155/567 (27.34%), Postives = 265/567 (46.74%), Query Frame = 1
Query: 1831 SENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYK---YHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNI---NFFSCILCIIFPFLI-----SKRTEFTKDFKTCQSESF-----------PD------FNEDNC-----------------RTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVY---FTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNSKLH 3387
E +PF EL +WAVLM++QK + FFW +ES+ ALVA ++ + Y + S D SE L+ + N F LAV L+E+ D+ ++ L+ + +NW +CL+LA S F+++ Q + W N+ +++ IL I+ P I + E ++ + PD F E R I K FY AP KF ++ ++ F++ +SYVVL + + E ++Y+ ++K E+F S +I +IK W++ +++N+ D I IV V LR+ +F + IY L + +Y+++L +LA +++ GP + M+ K++ + I+ + L++YGV +A YP + W + +++ PY+ M+G VY C ST + + C +L P L A Y+ I IL++N+LIA + + + S ++WKY Y I+ Y+DKP+LP P F +I L+F ++ + + K F + KLH
Sbjct: 584 PETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVVDDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYKVILSILVPPAILALEYKSKAEMAHIPQSQDAHQMTMEDSEHNLQNPDDIQMDVFKETRINDHVEVKHETEVVTRSRRLPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKLPIFP-SPQEWAVILYIFTSAIEKIREMFMSEGGKISQKIKVWFS-DYFNRSDFIAIVMFAVGFGLRFGSG---------NVFIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYG------EVYAYEIDVCANSTENNMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIFYHISSFLSFLCKRRKKDSAYGPKLFLTEEDQKKLH 1133
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Sea Lamprey
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2]) HSP 1 Score: 274.633 bits (701), Expect = 1.097e-76 Identity = 292/1049 (27.84%), Postives = 481/1049 (45.85%), Query Frame = 1
Query: 523 FVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTV--HYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQ---KQGDRVGIPVVLLIVEGGHDIFIEASRRVKEK--VSIVVCEGTGKASDIIGEAFR---EMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFS-GDISLSNDEWAAF---LKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCP--KSTNFRKTFLRLIGRP--FSKGLNDVKELLSKMIG-------------------FYEYPCSENDS--------------------------IKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKY---HQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNI---NFFSCILCIIFPFLI----------------------------SKRTEFTKD------------------------FKTCQSESFPDFNEDN--------CRTSISSKLRR---FYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQ--LAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDK 3252
+ RVSY + D ++ L+ +W++ L ISV GG +F++H K K +F +GLIKAA+TT A I T G+N G+ + +G+A++ S + ++ I +GIAPWG ++NR L V + +SN + K LN H+H+I DDG T K G R+ LE I+ + G G+PVV L+ EGG ++ + + E+ V +VVCEGTG+A+DI+ + + +C DG L + +K+ +H + ++C ++ + LITVF S H D+D AIL +L+K + + QL+L L W+RVDI K+ +F G + EWA + + D+++ +V F++L +EN ++ FLT L+ELY T + +N R R P + L DV ++ ++G + ++ S +++ +PF EL WAVLM++Q+ A FFW +ESL ALVA ++Y+ + S D + + L + F LA+ L+++ D+ +A L+ + NW +CL+LA S F+++ Q + W N+ ++F IL I+ P I R T+D +T + S D E R S S RR FY AP KF ++ +I F++ F+YVVL ++++ ++ E ++YL + +++ EIF S + +IK W +WN D + I+ VA+ LR Q L I +K +YSL V +Y+++L + A ++ +GP I M+ K++ + + I+ I LLS+GV QA + + D SW NI+ PY+ +FG VY + +T+ E C F+ P L A Y+ + I+++N+LIA + I + S +WK+ Y + Y+ K
Sbjct: 2 YARVSYDSRPDLLLQLMVKEWQMELPRLLISVHGGLQNFELHPKLKQVFSKGLIKAALTTGAWIFTGGVNTGVVNHVGNALKEHAS------RSSHKICTIGIAPWGVIENRGDLVGQDSHVVSPYQTLSNPLSKLN--LLNSLHSHFILVDDG-----TVGKYGAEAQLRRELEKHIATVACRAGMGQGVPVVGLVAEGGPNVIVTVLEYLLEEPPVPVVVCEGTGRAADILAFLHKNTDDTGELC--------DG---LHDEIVGTIKKTFNFSHGQAMHLLQTLLEC----MRRKELITVFHTGSEDHSDVDLAILTALLKGTNF-------SSADQLNLALAWDRVDIAKNHVFVYGQHWMVRLEWARWRRPMLDALVMDRVDFVKLLIENGVSMHKFLTITRLEELYNTSDHHQMSNLRILLHRFSHLPPDYKITLIDVGLVIEFLMGGAFRSMYTRKRFRLLYHNLYGQHRASVDNTRQRKQKMSTASGVGVTLDGSDPECSCFAYPFNELLAWAVLMKRQRMAMFFWQHGEESLAKALVACKLYRSLAGEAKQSREDELKWKRLWCARVKFGQLALDLLDQSFRQDERMAMKLLTYELRNWSNFTCLKLAVSSRHRPFVAHTCTQMLLADMWMGRLNMRKNSWFKVILSILMPPSILMLEYKSKAEMSHIPQSEELHQMGQEEREHRAAATRDIPMQRCLSRRVFLRLLSFAIRILLLRTVGNGSAADGGESGHKEEEGIWIRPSGLSLSRRIYEFYHAPIVKFWFNTLAYIGFLMLFTYVVLVKLQQLP-SVQEWFVILYLFMSAIERVREIFMSEPGKFGQKIKVWLD-GYWNINDSLGILLFFVAVALRSQSHLLIE------------AKIVYSLDVIFWYVRLLDVFAVNQNVGPYIMMIGKMMWQQCMLMIIMAIVLLSFGVARQAILFKEADPSWYLARNIVFQPYWMIFG------EVYAPEIDNNTDDEYP-PCTTGAFITPFLQAVYLFVQYIIMVNLLIAFFNNIYLEAKNISDKLWKFHRYHFTMYYHQK 994
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Sea Lamprey
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2]) HSP 1 Score: 261.536 bits (667), Expect = 1.927e-72 Identity = 275/1018 (27.01%), Postives = 458/1018 (44.99%), Query Frame = 1
Query: 523 FVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTV--HYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQKQ--------GDRVGIPVVLLIVEGGHDIFIEASRRVKEK--VSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDI---SELHQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGD---ISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKS-TNFRKTFLRLIGRPFSKGLN------DVKELLSKMIGFYEYPCSENDSI------------------------------KHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKY---HQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNI---NFFSCILCIIFPFLI-----SKRTEF-----TKDFKTCQSESFPDFNEDNCR-----------TSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKS----------RSD---RIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQ--LAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGN-----TVYFTWCNASTNYEVSNE---CPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDK 3252
+ RVSY + D ++ L+ +W++ L ISV GG +F++H K K +F +GLIKAA+TT A I T G+N G+ + +G+A++ S + ++ I +GIAPWG ++NR L V + +SN + K LN H+H+I DDG T K G R+ LE I+ ++ G G+PVV L+ EGG ++ + + E+ V +VVCEGTG+A+DI+ + H + +L + + +++L+ + H I E LI + + +F S +++L L W+RVDI K+ +F ++L W + D+++ +V F++L +EN ++ FLT L+ELY T TN K L R GLN + LL ++G CS ++ +PF EL WAVLM++Q+ A FFW +ESL ALVA ++Y+ + S D SE L+ + F LA+ L+++ D+ +A L+ + NW +CL+LA S F+++ Q + W N+ ++F IL I+ P I + E +++ + S D E + S+S ++ FY AP KF ++ +I F++ F+YVVL ++++ ++ E ++YL + +++ E+ RSD + +IK W +WN D + I+ VA+ LR Q L I +K +YSL V +Y+++L + A ++ +GP I M+ K++ + I+ I LLS+GV QA + + D SW NI+ PY+ +FG + C +E C F+ P L A Y+ + I+++N+LIA + I + S +WK+ Y + Y+ K
Sbjct: 1 YARVSYDSRPDLLLQLMVKEWQMELPRLLISVHGGLQNFELHPKLKQVFSKGLIKAALTTGAWIFTGGVNTGVVNHVGNALKEHAS------RSSHKICTIGIAPWGVIENRGDLVGQDSHVVSPYQTLSNPLSKLN--LLNSLHSHFILVDDG-----TVGKYGAEAQLRRELEKHIALQKIHTLACRAGMGQGVPVVGLVAEGGPNVIVTVLEYLLEEPPVPVVVCEGTGRAADILAFLHKNTDDTGWAHTHRHGQAMHLLQTLLECMRRKELVGTRARVRTHTHTCTHGSAAISGGPSVETLIALHRTGAAAGTNF----SSADQLNL---------------ALAWDRVDIAKNHVFVYGQHWMALMWARWRRPMLDALVMDRVDFVKLLIENGVSMHKFLTITRLEELYNTVSGPLTNPPKRPLLANSRSPPVGLNCTLNPPVIGNLLLMILG---GTCSAIQAVDNTRQRKQKMSTASGVGVTLDGSDPECSCFAYPFNELLAWAVLMKRQRMAMFFWQHGEESLAKALVACKLYRSLAGEAKQSEAVEDSSEELKQYSTEFGQLALDLLDQSFRQDERMAMKLLTYELRNWSNFTCLKLAVSSRHRPFVAHTCTQMLLADMWMGRLNMRKNSWFKVILSILMPPSILMLEYKSKAEMSHIPQSEELHQMGNGSAADGGESGHKEEEGIWIRPSGLSLSRRIYEFYHAPIVKFWFNTLAYIGFLMLFTYVVLVKLQQLP-SVQEWFVILYLFMSAIERVREVSDGARETRKAAGLRSDSEASAHRKIKVWLD-GYWNINDSLGILLFFVAVALRSQSHLLIE------------AKIVYSLDVIFWYVRLLDVFAVNQNVGPYIMMIGKMMANMFSIVIIMAIVLLSFGVARQAILFKEADPSWYLARNIVFQPYWMIFGEVYAPEIDGICVAVLAACENIMKNNTDDEYPPCTTGAFITPFLQAVYLFVQYIIMVNLLIAFFNNIYLEAKNISDKLWKFHRYHFTMYYHQK 969
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Sea Lamprey
Match: trpm2 (transient receptor potential cation channel, subfamily M, member 2 [Source:NCBI gene;Acc:799412]) HSP 1 Score: 142.124 bits (357), Expect = 2.476e-34 Identity = 161/663 (24.28%), Postives = 311/663 (46.91%), Query Frame = 1
Query: 1513 TWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGR----------------PFS-KGLND---------VKELLS---------KMIGFYEY-PCSENDS---------------------IKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINF--FSCILCIIFPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIF--KSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGY-YPQRDFSWIALSNILDYPYYTMFGVL--NLGNTVYFTWCNASTNYEVSN---ECP--ENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIY 3294
WNRVDI +IF+ D + + +++ + +FI LF+E+ ++++LT L+ LY P S + LR I P + K +N ++ELL KM F + P S+N P ++LF+WAVL+ +++ A FFW + + + AL+A+++ K + D+DR+ + + +E LA+ L++EC+ D+ A L+ ++ +WGG +CL +A + + F S+ Q + W G +++ + ILCIIFP LI R F+ T ++ R F+ AP T F + ++ F+ F+YV++ + E + +++ +IL++ ++F ++ + ++Y + WN++D++ ++ + ++ R L N + F+ +++ + F L+++ + +K LGPKI ++ +++K++ F ++ +++++YGV +Q ++ WI ++ PY +FG + +T + T + TN ++ CP ++L +L Y++ NILLLN+LIA +Y Q + N+ IWK+ Y L+ EY+ +P L P F ++Y
Sbjct: 379 AWNRVDIATSEIFTDDRKWQTGDLEQVMDAALLENRPEFISLFVEHGLILREYLTWARLESLYNGAPAS-SLLHILLRRISEGEKSPADPHRRWISTLPMAPKRMNHFSLYHISLLIRELLGDSTSMLYGNKMSRFSKLSPSSKNTGSTKGGTSLEFKGQTYNEGQLYCPDPERDLFIWAVLLNRRELANFFWSQGKDCMAAALMASKLLKAMVQEE-DDSDRTSDMLAQADNYEQLAIGLLDECYKDDELRAQKLLIRQLHSWGGATCLSMAYHANNKSFFSHSGVQALLTQIWWGGMSVDLKTWRVILCIIFPLLIYTR---IITFRWVLY----------AHTCTPTRWRNFWTAPITVFWANVVSYFIFLWLFAYVIIMDFQYTP-DWPEYVLYAWVLSLILEELRQVFTDPEKAGQWKAAVRY--IKDIWNRIDILALLLFTIGVICR--LIPNSINEST---FQAGRSVLCVDYMVFCLRLMHIFTVNKTLGPKIIIVKRMVKDIFFFLFLLGVWVVAYGVATQGILILNEQRLDWI-FRGVVYQPYLLIFGQFPTRVDSTTFDT--TSCTNNGINTSQPRCPVLGVDWLTILLTCLYLLFANILLLNLLIAMFNYTFQLVQDNTDTIWKFQRYELVNEYHSRPSLAPPLIVFSHLY 1015 HSP 2 Score: 90.8929 bits (224), Expect = 1.439e-18 Identity = 67/241 (27.80%), Postives = 103/241 (42.74%), Query Frame = 1
Query: 361 CSCGEIKKSHKENKI--PYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTN---ALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVG 1068
C C + H + P + W PT +FG I+FTG +L FVRV + + L+ W + L ISV GG +F + + + IF GL K A +T A IIT G G+ +G++++ + I +GIA WG + N+ L A+G+ +E + + L+ NH+H+I D+G Q + V R LE IS + G
Sbjct: 34 CECRHPRSEHANTALLKPTLLGQKWEPAKHTANEPTNAFGDIQFTG---LGQRLGKFVRVGNDTEPSVLFKLMMEHWHLDVPNLLISVTGGAKNFHLKPQLRTIFRHGLNKTARSTGIQGAWIITGGSYAGVMKYVGESVR---DFALASGSKEGKIVAIGIATWGIIHNKEHLIDAQGKFPAEYPMDEAGQGRLSCLDNNHSHFILVDNGTHGQYGVEIV--LRARLEQYISTQHTGSGG 266
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Nematostella
Match: EDO30135 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1N0]) HSP 1 Score: 268.47 bits (685), Expect = 4.729e-73 Identity = 196/754 (25.99%), Postives = 365/754 (48.41%), Query Frame = 1
Query: 232 SNVH---FAENDEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGP-RESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYV-KNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKI------SQKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRS-DG--VAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSH--EDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSK--GLNDVKELLSKMIG--FYEYPCSEN-------------------------------DSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRD---TDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRA--GFNINFFSCILCIIFPFLISKRTEFTKD 2316
S+VH F N +++I F EC F ++ S+C CG ++ H + + G E W+ C PT ++G+I+F G K ++R+S+ + ++ L+ +W + L ISV GG F + + + +F +GLIKAA TT A IIT G N G+ +G+A++ Q + ++ +GIA WG V K +++ G+ HQ L+ NH+H+ DDG T+ K G R +E I S+ + +G+PVVLL++EGG + +K+KV VV +G+G+A+ ++G A+ H + R+ DG + ++ +++ ++ K++E + D+ I+D++++E +I+V+ + +D+D AIL +L+K +N++ +QL+L L WNR+D+ K IF+ + + + +A + +++ K +F ELFL+N ++++FL+ +IL +LY P +T + + +G+ K ++ V E++ +++G F Y + D + P+ ++FLWAVL +++ A+ W E + AL+A+R+ K + D TD S L FE AV +++EC + ++ ++ L+ ++ +++ ++ LELA + F+++ CQ + W N ++ ++C+ P LI F D
Sbjct: 16 SHVHLNKFGSNQLSQSKKSWIARNFSRRECIRFVPKSHDV----SRCKCGRPRERHSQQALESGQGSEEWNVASCTTKHPTNAYGEIDFEG--YGGQKRAPYLRMSHDTDANLVITLMLKRWNLEIPNLVISVTGGAKSFVLKPRLREMFRRGLIKAAKTTGAWIITGGTNTGVMKHVGEAVKEQQLMFGSDTQ----VNVIGIATWGIVDKQSDLISEKNGKYPALYSMEPTPGHQGAMLDPNHSHFFLVDDG-----TEGKYGVEIGMRSRIEEAIMKVKTDSRSEAGSIGVPVVLLVLEGGPNTVATMYELIKKKVPAVVIDGSGRAASVVGFAY--------NHTIKRNVDGQTINVIDPQYEDEVRAKVVE--VFGAKGADKTYSMIKDVLEDEKMISVYSLDGEISQDIDLAILKALLK-------ANRSSPVAQLNLALAWNRIDLAKSDIFTEEQQWTTETLSAAMLTALLDDKAEFAELFLQNGLSMREFLSLDILCKLYAEVPGNTTIKPLLQKEMGKRQVKTIDMDVVGEVIEELMGDMFESYYRKDGHYFGELASYAEGLVLKNRKSSKDLLANINRIDPLPTPYLDVFLWAVLCNRRELARVLWEAGREPMAAALMASRLLKRMASRAQEDNTITDISSDLYDHARLFEERAVGVLDECFNENETLSQTLLVRELDHYSRMTALELAVSAESQDFIAHTSCQVLLTRLWMGTMAMNTRWWKVLVCLYLPVLIFPIIYFVPD 737 HSP 2 Score: 87.4261 bits (215), Expect = 2.979e-17 Identity = 112/516 (21.71%), Postives = 242/516 (46.90%), Query Frame = 1
Query: 2344 PDFNED--------NCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLT-----IH--EIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQ-----RDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNSKLHIDKPMAFKHDTLNIFSNIKSDSDLNKLIKYFENYSQKFVIKNIAIEKQKSIKSGISRMEIRSKSIFKELENIQTKLNKIQIKNVKKVQEGSFTNTNGEYQNITKQPKDSMALLLTSLNNNILVLQDEVNRIGQEVNIVSTENSPVVIT 3831
P+ ED N + ++ FY AP +KF + +++FI ++YVVL+ R IH EI+ ++ +++++ ++ I ++ +++ + WN VD+ + I+A++LR+ +T+ + F S+ I SL + F ++ L++ + ++ LGPK+ M+ K++++L F I+ +F ++YG+ A +P R+ +W+ +++++ YPY+ M+G L + E P+ +L P+L A Y++ NILLLN+LIA +Y + + +S +WK+ Y L+ EY+ +P+ P +I + + ++ RC + +I +++ + +N+ +F + I +Q+ SG +E R +++ ++ I ++LN++ + ++ + + T+ NG + + +A + L++N LQ + + Q+ + P+ +T
Sbjct: 807 PEIREDDSMEVIMRNKKLGFCDRIMHFYSAPFSKFVGNVVGYLAFIFLYAYVVLFNFPRFDPAKTLGGIHPTEIVLYFWVFTILIEEIRQLAAKPPKYIKDKVSVYFS-DTWNFVDIFSLTVFIIAIILRF-------FTNSRI-FTASRIILSLDIIFFIVRSLQIFSVNRLLGPKLVMIQKMMQDLAQFIIILAVFTIAYGIALHAVMFPSPGIYARNNTWVTITSVVQYPYWQMYGEL------FLDEIQGEKPKEFGEVDPDGRWLSPLLLAIYMVFTNILLLNLLIAIFNYTFERVQEDSDKVWKFQRYDLVQEYHSRPVFAPPLVLLGHILIFIRWVWRMCRCGHPPRGSTMKIGLSPAEM-----------------------------EQMDNW--EFQAAEMYIHQQQQKNSGT--LEERVRALGDRVDCINSQLNRV-LDSMSGTRAHALTDGNGLEGGHDSEGR--LARMEVELSSNSESLQKILALLQQQPPVKGQAAVPIQLT 1271
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Nematostella
Match: EDO47658 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLT7]) HSP 1 Score: 157.918 bits (398), Expect = 6.675e-39 Identity = 132/433 (30.48%), Postives = 230/433 (53.12%), Query Frame = 1
Query: 454 LPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQ-YSQSYLYDKMKHNNF-ISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVG---YFRQALENKISQKQGDRV--GIPVVLLIVEGGHDIF---IEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDE------AIKCIEDIIKNELLITVFDIKSHE-DLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELY 1701
LPT +FG++EF G ++R+++ + ++ L+ +W + L ISV GG +F + K K + +GL+KAA TT A +IT G N G+ +G+A++ ++ +++K+ + +GIA WG V ++ +L K V Y +++ ++ + L+ NH+H+I D+G T + G FR +LEN I+ K+ + G+PVVLL++EGG + +E+ R V +V+ EG+G+A+DI+ A R + S +M GVA + E + +L + IE+ +E D +KC+ K E +T+F + ++D AIL +L+K + L QLSL L W+R DI K +IF+ D + ++++ +V+F++L L+N ++ +FLT L+ELY
Sbjct: 15 LPTDAFGELEFQGAG--QPSRAKYIRLAHDTDPELVLRLLCGEWALDLPKLLISVTGGAKNFILSPKIKRVLREGLLKAAQTTGAWVITGGTNTGVMRHVGEAVKGHTVMSRGEQLKNTAHQVHLIGIASWGIVDHKEMLVNPKVEVVPYQMTSSMQS-RGACLDNNHSHFILVDNG-----TDGEYGGEISFRASLENLIASKKMAQKFHGVPVVLLVLEGGPNTIRTVLESVSRCP-AVPVVIAEGSGRAADILAFAHRFIAP--SNGEM---SGVADVVEH-RQLLHK--IEKSFAECSPEDRLSIYQNVLKCVA---KRE-FVTIFCVDDGGLEVDKAILRALLKSQH-------SQLEDQLSLALVWDRADIAKTEIFTEDQKWEVPMLETAMMEALLHDRVEFVDLLLDNGVSMANFLTVKRLEELY 419 HSP 2 Score: 88.1965 bits (217), Expect = 1.628e-17 Identity = 112/462 (24.24%), Postives = 203/462 (43.94%), Query Frame = 1
Query: 2041 FENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINF---FSCILCIIFPFLIS----KRTEFTKDFKTCQSESF----PDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHE----------IMFMIYLVLM-----------------ILDKFVEIFKSRSDRIYGRIKYW---------WTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNECPE----NNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPF 3273
F ++A+ L++EC+ + +A L+ WGG + L LA S +F+++ CQK + W + +L I+FP LI + E + T +S PDF+ + R S++ Y+ F + + + + L G+ + + + I+++++LV+ +L FV + R I W W N WN D +V +A+ LR R +YSL + + +++L + + K LGP + M+ ++ +++ F I+++FLL+YGV QA +P SW ++ I PY+ ++G L + + Y +S + E + P+ L+ ++ A Y+++ NILLLN+LIA + ++ NS IWK+ +SL++EY +P L PF
Sbjct: 595 FYDIALGLLDECYKANDVLAQRLLIYHPVYWGGRTSLSLAVASRHEEFVAHSCCQKKLTEIWMGALKTGYNGSLKVLLGILFPPLIFALEFRSREEMQRVPTTDDDSADDLPPDFDPYHHREPGSAQYNDGYLGDGVAFVKNRKSSGNEEEPIVEIRLLGLGKRIIGFYNAPITKFWSNLIVYLLFLVVFSHVILIELPPVPSIEEWVLIGFVFSLCAEEVRQVRVINVWNFSFFESSDWASNVWNLCDGFAMVLFFLAVGLRLNPGT----------LRIGHLVYSLDIMLWIIRLLDIFSVSKDLGPYVVMIGRMTIDMMYFLVIMVVFLLAYGVAQQAILFPHEKPSWELITKIFFRPYFQVYGELFIEDVDY-----SSNSRETAFSTPKFDEYGGRLVTVIMAFYLLVANILLLNLLIAIFNNTFSEVQANSNQIWKFQRFSLVMEYRQRPRLVPPF 1041
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Medaka
Match: trpm2 (transient receptor potential cation channel subfamily M member 2 [Source:NCBI gene;Acc:101170060]) HSP 1 Score: 259.996 bits (663), Expect = 4.683e-70 Identity = 289/1074 (26.91%), Postives = 488/1074 (45.44%), Query Frame = 1
Query: 361 CSCGEIKKSHKENKIPYGPR----ESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQ-YSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQKQGDR----VGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLP-ESFKNVLKRKLIEQDISELHQ------VDEAIKCIEDIIKNELLITVFDIK--SHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFL-TANILKELYETCPKSTNFRKTFLRLIGRP---------FSKGLNDVKELLSKMIGFYEYP----------------CSENDSIKHPFQE---------LFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN--FFSCILCIIFPFLI----------------SKRTEFTKDFKTCQSE--------SFPDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKY-WWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRD--FSWIALSNILDYPYYTMFGVL--NLGNTVY-FTWCNASTNYEVSNECP---ENN------FLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYI 3291
C CG K++H I P E+W++ + +PT +FG+I+F G T +K + RVS + + DL+ +W + L ISV GG +F + +N+F +GLIK A TT A IIT G N G+ +G A++ YS S I +G+A WG + NR L +G ++++ + + L+KNHTH++ DDG T G R LE IS KQ + V IPVV +++EGG +K V+ EGTG+ +D+I + V+ LP + L +L+E+ + ++ V E K I+DI++ L+T+F + SH D+D AIL +L+K + +QL L + WNRVDI K +IF+ D S+ + + +++ K +F+ L LEN +++ FL L LY P RK R+ + + ++V+ LL P S+N+ P E +FLWAVL + A+ W +C +S+ AL ATRI K D + +E + +++E A+ + EC++ D+E A L+ + WGG + L LA K+ D +F++ Q + W +++ ++C++F LI +K+ E K K S PD S +L Y +PQ KF + ++ F+ F+ V++ ++ E++ +++ ++ ++F ++F SD +IK + + WN +D++ I+ ++ + R L Y K+V+ +V F L+++ + + LGPKI ++ +++K+L F ++ I++++YGV Q G D WI I + PY +FG NL + C+ + + +CP EN+ +L + Y++ NILLLN+LIA ++ Q++ N+ IWK+ Y LI EY+ +P P PF F ++
Sbjct: 55 CKCGYSKEAHNVEAI--KPEDFVGETWNKHRHVLDVPTNAFGEIQFDGLQQTTAK---YARVSSETSPEVLYDLLTEQWHLLPPNLLISVTGGAKNFNLKPHLRNMFHRGLIKVAQTTGAWIITGGTNAGVMKHVGQAVRDYSLSNSIQGQ-----IVAIGVATWGVIHNREALINEEGCFPALYMTDKTSQGRLSCLDKNHTHFLLVDDG-----THGHYGVEIELRTCLEKCISGKQLGKKDSSVTIPVVCVVLEGGPGTLNTIFNAMKNGTPCVIFEGTGRIADVIAQ-------------------VSGLPLQQITITLIHQLMEKFFGQEYKKFTELSVIEWTKKIQDIVRMSHLLTIFRVTEDSHGDVDVAILKALLKASRSSETLTLDCWKTQLELAVAWNRVDIAKTEIFTEDSLWSSADLHQAMFSALVGNKPQFVTLLLENGMSLRKFLQNEETLCNLYREMPSCIFLRKLAKRVHSKADLVDSNNITLTHVSDEVRHLLGNATRHIYPPYVEQRYCMSAEDLSLSLSKNNGAPRPAGEVAQRDASSDVFLWAVLQNNRDLAEIAWEQCQDSICAALAATRILK-KLAGGESDAEEAEEMLNQASHYEEHAIGVFSECYNTDEERALKLLVHVSNFWGGTTSLWLALKAEDKRFVALSGVQAFMTRVWCGELSVDNHILRVLICMLFFPLIYTGFLAFRHDELFQKEAKKQEAMKKVKRVTGNTHGAQSLGSAPDKP-----LSCWDRLVSLYGSPQVKFYWNIVSYFFFLNLFAGVLMMDFHATP-SVPELLLYVWVFSLVCEEFRQLF-CNSDGFGFKIKAKLYITDLWNILDVLSILLFLLGLAFR--LTSELFYAGKIVL------CIDFVV--FCLRLMAIFTISQTLGPKIIIVRRMMKDLFFFMFLLSIWVVAYGVAKQ-GILIHNDTRLDWIFRGAIYE-PYLIIFGNFPENLAEAKFSLDSCSMNGTDPLKPKCPILNENHAPVFPEWLTITMLCVYLLFANILLLNLLIAIFNFTFQEVQDNTDRIWKFQRYELIKEYHSRPAAPPPFIIFSHL 1074
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Medaka
Match: trpm2 (transient receptor potential cation channel subfamily M member 2 [Source:NCBI gene;Acc:101170060]) HSP 1 Score: 259.61 bits (662), Expect = 6.223e-70 Identity = 289/1074 (26.91%), Postives = 488/1074 (45.44%), Query Frame = 1
Query: 361 CSCGEIKKSHKENKIPYGPR----ESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQ-YSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKISQKQGDR----VGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLP-ESFKNVLKRKLIEQDISELHQ------VDEAIKCIEDIIKNELLITVFDIK--SHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFL-TANILKELYETCPKSTNFRKTFLRLIGRP---------FSKGLNDVKELLSKMIGFYEYP----------------CSENDSIKHPFQE---------LFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNIN--FFSCILCIIFPFLI----------------SKRTEFTKDFKTCQSE--------SFPDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKY-WWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRD--FSWIALSNILDYPYYTMFGVL--NLGNTVY-FTWCNASTNYEVSNECP---ENN------FLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYI 3291
C CG K++H I P E+W++ + +PT +FG+I+F G T +K + RVS + + DL+ +W + L ISV GG +F + +N+F +GLIK A TT A IIT G N G+ +G A++ YS S I +G+A WG + NR L +G ++++ + + L+KNHTH++ DDG T G R LE IS KQ + V IPVV +++EGG +K V+ EGTG+ +D+I + V+ LP + L +L+E+ + ++ V E K I+DI++ L+T+F + SH D+D AIL +L+K + +QL L + WNRVDI K +IF+ D S+ + + +++ K +F+ L LEN +++ FL L LY P RK R+ + + ++V+ LL P S+N+ P E +FLWAVL + A+ W +C +S+ AL ATRI K D + +E + +++E A+ + EC++ D+E A L+ + WGG + L LA K+ D +F++ Q + W +++ ++C++F LI +K+ E K K S PD S +L Y +PQ KF + ++ F+ F+ V++ ++ E++ +++ ++ ++F ++F SD +IK + + WN +D++ I+ ++ + R L Y K+V+ +V F L+++ + + LGPKI ++ +++K+L F ++ I++++YGV Q G D WI I + PY +FG NL + C+ + + +CP EN+ +L + Y++ NILLLN+LIA ++ Q++ N+ IWK+ Y LI EY+ +P P PF F ++
Sbjct: 55 CKCGYSKEAHNVEAIK--PEDFVGETWNKHRHVLDVPTNAFGEIQFDGLQQTTAK---YARVSSETSPEVLYDLLTEQWHLLPPNLLISVTGGAKNFNLKPHLRNMFHRGLIKVAQTTGAWIITGGTNAGVMKHVGQAVRDYSLSNSIQGQ-----IVAIGVATWGVIHNREALINEEGCFPALYMTDKTSQGRLSCLDKNHTHFLLVDDG-----THGHYGVEIELRTCLEKCISGKQLGKKDSSVTIPVVCVVLEGGPGTLNTIFNAMKNGTPCVIFEGTGRIADVIAQ-------------------VSGLPLQQITITLIHQLMEKFFGQEYKKFTELSVIEWTKKIQDIVRMSHLLTIFRVTEDSHGDVDVAILKALLKASRSSETLTLDCWKTQLELAVAWNRVDIAKTEIFTEDSLWSSADLHQAMFSALVGNKPQFVTLLLENGMSLRKFLQNEETLCNLYREMPSCIFLRKLAKRVHSKADLVDSNNITLTHVSDEVRHLLGNATRHIYPPYVEQRYCMSAEDLSLSLSKNNGAPRPAGEVAQRDASSDVFLWAVLQNNRDLAEIAWEQCQDSICAALAATRILK-KLAGGESDAEEAEEMLNQASHYEEHAIGVFSECYNTDEERALKLLVHVSNFWGGTTSLWLALKAEDKRFVALSGVQAFMTRVWCGELSVDNHILRVLICMLFFPLIYTGFLAFRHDELFQKEAKKQEAMKKVKRVTGNTHGAQSLGSAPDK-----PLSCWDRLVSLYGSPQVKFYWNIVSYFFFLNLFAGVLMMDFHATP-SVPELLLYVWVFSLVCEEFRQLF-CNSDGFGFKIKAKLYITDLWNILDVLSILLFLLGLAFR--LTSELFYAGKIVL------CIDFVV--FCLRLMAIFTISQTLGPKIIIVRRMMKDLFFFMFLLSIWVVAYGVAKQ-GILIHNDTRLDWIFRGAIYE-PYLIIFGNFPENLAEAKFSLDSCSMNGTDPLKPKCPILNENHAPVFPEWLTITMLCVYLLFANILLLNLLIAIFNFTFQEVQDNTDRIWKFQRYELIKEYHSRPAAPPPFIIFSHL 1074
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Medaka
Match: trpm3 (transient receptor potential cation channel subfamily M member 3 [Source:NCBI gene;Acc:100533512]) HSP 1 Score: 249.98 bits (637), Expect = 1.192e-66 Identity = 220/740 (29.73%), Postives = 343/740 (46.35%), Query Frame = 1
Query: 274 RNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYG-----------------PRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDI--FIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKS--HEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAA-----FLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKG---------LNDVKELLSKMIGFYEYPCS------------------------------------------ENDSIKH---PFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRD---TDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTW 2226
+++I F EC + V+ K+ +C CG + H +P G E WS ++ PT +FG IEF G +N + +VRVSY K D ++ L+ +W++ L ISV GG +F++ K K +F +GLIKAA+TT A I T G+N G+ +GDA++ S K I +GIAPWG V+N+ L + +SN + K LN H+H+I D+G T K G R+ LE IS QK R+ G+PVV LIVEGG ++ + R V +VVC+G+G+ASDI+ AF HK G+ + ES ++ L + + Q + + +K + LITVF + S H+D+D AIL +L+K + QLSL L WNRVDI + +IF + +W + D+++ +V F++L +EN ++ FLT + L+ELY T +N T L+ R KG L D+ ++ ++G Y C+ ++ I H PF EL +WAVLM++QK A FFW +E++ ALVA ++ K + + D S+ L F LAV+L+++ + D+++A L+ + +NW +CL+LA + F+++ Q + W
Sbjct: 44 KSWIERAFSKRECVHIIVSAKD----PHRCCCGRLIGQHV--GLPPGISSSQNDKAERMAKNDSLSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSYDTKPDLLLHLMTKEWQLDLPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHAS------KSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPLSKL--TVLNSLHSHFILADNG-----TTGKYGAEVRLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDIL--AF--------GHKYSEEGGI--INESLRDQLLVTIQKTFTYSRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGAN-------ASAPDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSVHRFLTLSRLEELYNTRHGPSN---TLYHLV-RDVKKGNLPPDYRISLIDIGLVIEYLMGG-AYRCNYTRKRFRTLYHNLFGPKRDDMPIRRGRQKTTRKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFAQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMW 733 HSP 2 Score: 83.5741 bits (205), Expect = 1.277e-15 Identity = 88/312 (28.21%), Postives = 163/312 (52.24%), Query Frame = 1
Query: 2377 ISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVS---NECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVL 3303
+ K+ FY AP KF H+ ++ +++ F+Y+VL M + + E + + Y+ ++K EI S ++ ++K W +WN D++ I+ V MVLR Q + + + IY + + +Y+++L + +K LGP + M+ K++ +++ F I+L+ L+S+GV QA P D SW+ NI PY+ ++G + N +T+ V C +++P + A Y+++ NILL+N+LIA + ++ S +WK+ Y LI+ ++++P+LP P F +I VL
Sbjct: 830 LGRKIYEFYNAPIVKFWFHTLAYVGYLMLFNYIVLVKMD-LWPSPQEWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQ-EYWNITDLMAILIFSVGMVLRLQ---------EPPFMSYGRVIYCINIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPNEDPSWMLARNIFFMPYWMIYGEVFADQIDPPCGQNITTDDGVVVALPACKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHITMVL 1130
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Medaka
Match: trpm5 (transient receptor potential cation channel subfamily M member 5 [Source:NCBI gene;Acc:101161300]) HSP 1 Score: 213.386 bits (542), Expect = 9.174e-56 Identity = 255/1020 (25.00%), Postives = 457/1020 (44.80%), Query Frame = 1
Query: 472 GKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQ-YSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFD-DGYRLQMTKKKVGYFRQALENKIS-QKQGDRVG---IPVVLLIVEGGHDIFIEASRRVK---EKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSH-EDLDFAILYSLIKRMDLLCDXXXXXXXX---XXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLR-------LIGRPFSKG---------------LNDVKELLSKMI-----GFYEYPCSENDS-----------------IKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSI--EFTWRAGFNINFFSCILCIIF--PFLISKRTEFT-KDFKTCQSESFPDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKR--MQLTIHEIMFMIYLVLMILDKFVE-IFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRD-FSWIALSNILDYPYYTMFGVLNLGNT---VYFTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSS--------YICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQV 3300
G I+F G + T K FV+V + I ++ +W ++ L ++V+GG +M ++ +GL+KAA +T A I+T GL GIT +G A++ +S + ++ + +GIAPW + NR L AK V Y ++ SL+ NH+H++ + D R T + R L IS Q+ G G IPV+ L+V G I R K ++ G+G +DI+ M R C + +L ++F N DIS +K I+ I+ + L+TV D + +LD IL +L+K C S +L L + WNRVDI K IF+GD+ + + D++I K F+ LF++N N+ +FLT L+ELY + + + L+ L+G + G L +V ++L + GFY+ +E +HP+++LFLWAVL +Q+ A +FW E++ AL +I K R + + + +++ K +E A+ + EC+ ++ A L+ ++ W + L LA+++ F ++ Q+++ + W A S ++ F P + + +F + + +E +D+ + RRF+ AP T F + + +F+ F+YV+L K + EIM ++ ++L++ + F I + K + ++WNK DM+ I+ L + GV + +T+ ++ F L+++ + A HK+LGPKI ++ +++K++ F + ++L++YGV +QA +P W+ L PY +FG + L + C +N V P P ++A +++I+ +++ ++ Y Q + GN+ + WK+ Y+LI+EY +P L PF ++ Q+
Sbjct: 38 GDIDFCGTNKTRGK---FVKVRSNTEPVQIYQMLTQEWGLSPPHLVVAVVGGDELAQMKPWLRDTLRKGLVKAAQST-AWILTNGLRFGITKHLGQAVRDHSLASTSSTVR----VVAIGIAPWNMIHNREALLSAKDEPVVYT-PQDLPHGSVYSLDNNHSHFVLVEEDPARPGATSE----MRVKLLKHISLQRTGYGAGSFEIPVLCLLVHGEPKILKFLQRMYKGIANSTPWLILAGSGGVADIL---VTLMNRGCWDTDSVHE----LLLDTFPNAHH----SADISNW------VKLIQKILDHGHLLTVHDPEQETSELDTVILKALVK-----CKSQSQEAQDFLDELKLAVAWNRVDIAKSDIFNGDVEWKACDLEEVMMDALINDKPDFVRLFVDNGVNLGEFLTYGRLQELYWSVSEKSLLHNLLLKKYDEKQLLLGAARTPGPPGHYPSEQGKPRFTLFEVAKVLKDFLHDSCKGFYQKVPTEKPPKGRLFQSQKNLPELEELCEHPWRDLFLWAVLQNRQQMANYFWAMGPEAVAAALAGCKILKEMARLE-SEAESARSMKEAK--YEQFALDVFGECYSNSEDRAYALLVRRTHCWSKSTVLNLATEADAKSFFAHDGVQQALLTKIWWGAMTTDTAISKLVVSFFCPPLIWTNLIKFQFVELDSLDTEKALMLTDDDDPRFFLRRWRRFWSAPVTVFLGNVIMYFAFLFLFTYVLLLDFKAPPQGPGVPEIMLYFWVFTLVLEEIRQSFFTDEEMNIIKKFKL-YVEDNWNKCDMVAIL-----------LFVVGVSCMAAGTYEAGRTVLAIDFMVFTLRLIHIFAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLIAYGVATQALLHPNDPRIDWV-FRRALYRPYLHIFGQIPLEEIDARMPKINCTDDSNEIVMGLLPP----CPNIYANWLVILLLVIFLLVTNVLLLNLLIAMFYTFQVVQGNTDIFWKFQRYNLIVEYYSRPALAPPFIIISHLSQL 1002
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Medaka
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:101156483]) HSP 1 Score: 206.068 bits (523), Expect = 4.969e-53 Identity = 165/537 (30.73%), Postives = 262/537 (48.79%), Query Frame = 1
Query: 253 NDEKMQ-YRNYINAKFKSVECRYFSVAIK---------EIDDKNSKCSCGEIKKSHK----------------ENKIPYGPR-ESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGY---FRQALENKIS-QKQGDRV--GIPVVLLIVEGGHDIFIEASRRVKE--KVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHE--DLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLI 1752
+DE +Q + +I F EC Y K +I + +C CG + + H EN P P E WS E+ PT ++G I F G ++S +VR+SY + + ++ L+ +W + + ISV GG +F++H + K + +GLIKAA+TT A I+T G+N G+ +GDA++ S K I +GIAPWG ++NRN L + + N + K LN H+H++ DDG T K G R+ LE I+ Q+ R+ G+PVV LI EGG ++ + ++E V +VVCEGTG+A+DI+ ++ + + +D +A + ++F D L Q+ + + +K++ LITVFDI S E D+D AIL +L++ + + QL L L W+RVDI K+ +F L + D+++ +V F++L +EN ++ FLT N L+ELY T K + T L L+
Sbjct: 11 DDEDIQSQKPWIEVTFTKRECVYILPVSKDPHRCLPGCQICQQLVRCCCGRLVRQHAGFTASLATKYSDVKLGENPNPPMPELEEWSVEKHTEVSPTDAYGVINFQGG--SHSYRAKYVRLSYDSRPESVLRLMLKEWHMELPKILISVHGGVQNFELHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHCSRSAKK------ICTIGIAPWGVIENRNDLIGKDIIAPYQTLLNPLSKLN--VLNNLHSHFLLVDDG-----TVGKYGAEVKLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQETPPVPVVVCEGTGRAADILAYVHKQTEEGGGLPDGVETDIIATIKKTF------NFSHSDAIHLFQM------LMECMKSKELITVFDISSEEQQDIDVAILKALLQGTN-------SSPFDQLVLTLAWDRVDIAKNHVFVYGQQLLVSSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTINRLEELYNT--KQSPNNPTLLHLV 511 HSP 2 Score: 154.066 bits (388), Expect = 4.804e-37 Identity = 153/568 (26.94%), Postives = 273/568 (48.06%), Query Frame = 1
Query: 1834 ENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYK---YHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNI---NFFSCILCIIFPFLI-----SKRTEFTK------DFKTCQSES---FPDFNED--------------------------NCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVY---FTWCNASTNYEVSNECPENN-FLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNSKLH 3387
E +PF EL +WAVLM++QK + FFW +E++ ALVA ++ + Y + S D S+ L+ + N F LAV L+E+ D+ +A L+ + +NW +CL+LA S F+++ Q + W N+ +++ IL I+ P I + E D + +S F + +ED + + ++ K+ FY AP KF ++ ++ F++ ++YVVL M + T E + ++Y+ ++K E+F S + +I +IK W++ +++N D + IV + LR LA F + +Y L + +Y+++L +LA +++ GP + M++K++ + I+L+ LLSYGV +A YP + SW +++ PY+ M+G VY C ++ V C +L P L A Y+ + IL++N+LIA + + + S ++WK+ Y I+ Y++KP+LP PF ++Y + C +K + + K F + KLH
Sbjct: 631 ETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEENMAKALVACKLCRSMGYEAKKSDVVDDTSDKLKDYSNDFGTLAVDLLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSHLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKSKAEMAHIPQSQDDHQMTMEDSEHNFQNLHEDIQMDVFKEARSHDHVETKHDMEMHVRSRKLPLTRKIYAFYHAPIVKFWSNTLFYLGFLMLYTYVVLVKMIQAPST-QEWVVIVYIFTSAIEKIREMFMSEAGKISQKIKVWFS-DYFNVSDFLAIVTFFIGCGLR--LAGGDA-------FLPGRIVYCLNIIFWYVRLLDILAVNQQAGPYVMMIAKMVANMFYIVVIMLVVLLSYGVPRKAILYPNEEPSWTLARDVVFQPYWMMYG------EVYAYEIDVCANNSEDSVKPLCASAGVWLTPFLQAVYLFVQYILMVNLLIAFFNNVYMQVKSISNLVWKFQRYHFIMAYHEKPVLPPPFILLCHVYSLFCMC-RKRKKESTYGPKLFLTEEDQKKLH 1180
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Planmine SMEST
Match: SMESG000064622.1 (SMESG000064622.1) HSP 1 Score: 2150.17 bits (5570), Expect = 0.000e+0 Identity = 1122/1146 (97.91%), Postives = 1127/1146 (98.34%), Query Frame = 1
Query: 133 MIKRPSSKRTSQNEDYTVTIRQARCKINESCRESNVHFAENDEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKGLNDVKELLSKMIGFYEYPCSENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINFFSCILCIIFPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNSKLHIDKPMAFKHDTLNIFSNIKSDSDLNKLIKYFENYSQKFVIKNIAIEKQKSIKSGISRMEIR 3570
MIKRPSSKRT+QNEDYTVTIRQARCKINES RESNVHFAENDEKMQYRNYINAKF+SVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNR ILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDSNQNPLSSQLSLCLTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKGLNDVKELLSKMIGFYEYPCSENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQ +CILCIIFPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISSKLRRFY+APQTKFCIHSFTFISFIIYFSYVVLYGMKRMQ+TIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKVDMIIIVFAIVAMVLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKELLIFSTIILIFLLSYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNECPENNFLIPILFAGYVIIINILLLNILIATSSYICQDIH NSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNSKLHIDKPMAFKHDTLNIFSNIKSDSDLNKLIKYFENYSQKFVIKNIAIEKQKSIKSGISRMEIR
Sbjct: 1 MIKRPSSKRTTQNEDYTVTIRQARCKINESYRESNVHFAENDEKMQYRNYINAKFQSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRKILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDSNQNPLSSQLSLCLTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKGLNDVKELLSKMIGFYEYPCSENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQ----------------NCILCIIFPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISSKLRRFYLAPQTKFCIHSFTFISFIIYFSYVVLYGMKRMQVTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKVDMIIIVFAIVAMVLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKELLIFSTIILIFLLSYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNECPENNFLIPILFAGYVIIINILLLNILIATSSYICQDIHRNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNSKLHIDKPMAFKHDTLNIFSNIKSDSDLNKLIKYFENYSQKFVIKNIAIEKQKSIKSGISRMEIR 1130
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Planmine SMEST
Match: SMESG000064632.1 (SMESG000064632.1) HSP 1 Score: 1291.56 bits (3341), Expect = 0.000e+0 Identity = 684/1077 (63.51%), Postives = 836/1077 (77.62%), Query Frame = 1
Query: 133 MIKRPSSKRTSQNEDYTVTIRQARCKINESCRESNVHFAENDEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKGLNDVKELLSKMIGFYEYPCS-ENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINFFSCILCIIFPFLISKRTEFTKDFKTC---QSESFPDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSK 3351
M K P K++ N++++ +IRQAR KI +S R S++ F+ENDEK YR ++ + F S+ECR FS + +D N+KC CGE KK+HK +K P+ + W E + ME++ T SFGKIEF GEDITN+KLTDFVRVSY DKLDDI++L+FNKW I GTLCISVIGGTIDFKM KEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVK RNILE AKGRTVHYNVSNEVE++QP+SLNK+HTHYIF DDGYRLQM++KKV YFRQALENKISQK G+R IPVVLLIVEGGH++ +E SR AS+I+GE F+E+ + + RS ++ E+++ LK KLIEQ+I ELHQVDE +KCIE+I+K E LIT+F IKSH+DLDFAIL+SLIKRMD LCD NPLSSQLSLCL WNR+DIVKDKIF GDISLSN EW AF K+SI+ G++ FIELFLENVSN+ DFLT IL +LY+T PKS NFRKTFL LIGR FSKGL++ KEL+ KMIG ND HPFQELFLW+VLMEK KCA+FFWGKCD++L LALVATRIYK + TS+RDTDR TL WK FENLAVKLIEECHDIDQE AAYLIEK+ + GI+CLELA+KS +LKFMSNIVCQ SI+FTWRAGF I+F+ CILCI+FPFLI + ++TKD K +++ D+ E +KL+RFY+APQTKF IHS TF SF++YFSYVVLYGM+RM L+ HE +FM YLV++I + +E+F+SRS I+ R+KYWW FN+ NK+D III+ AI AM LRY LA + D ++++R SKTIYSLIVG Y++ LRLL HKKLGPK+ MM++++K+L+I+ II+IFL SYGVTSQAGYY QRDFSW AL+N+ YPYYTM GV+ VY +WC+ + N S +CPE N ++PILFA +V+I NIL++NIL+AT+ +C++IH +SI IWKY+ YSL+LEY KPI+P+PFS ++IY +L + CYNL NSK
Sbjct: 1 MRKTPLKKQSFINDEFSASIRQARFKITDSNRGSHIRFSENDEKALYRKFVKSNFHSIECRKFSSLEEILDHNNAKCMCGEAKKNHKIDKTPFSLCDPWKENESMEVISTDSFGKIEFFGEDITNTKLTDFVRVSYNDKLDDILELLFNKWNINVGTLCISVIGGTIDFKMRKKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKKRNILESAKGRTVHYNVSNEVEQNQPVSLNKHHTHYIFVDDGYRLQMSRKKVAYFRQALENKISQKLGERAAIPVVLLIVEGGHEVLVEGSR----------------ASNILGEVFQEVSNSSWKRERTRSGDTSVFSENYRKALKTKLIEQNICELHQVDEDVKCIEEIVKKEFLITLFYIKSHQDLDFAILHSLIKRMDFLCDPRYNPLSSQLSLCLIWNRIDIVKDKIFLGDISLSNAEWIAFFKESIMKGRIDFIELFLENVSNLHDFLTTEILDDLYKTYPKSNNFRKTFLILIGRSFSKGLSEAKELVFKMIGVNRKQLKMRNDYSLHPFQELFLWSVLMEKNKCARFFWGKCDDALCLALVATRIYKCLRGTSVRDTDRQVTLTLWKESFENLAVKLIEECHDIDQETAAYLIEKEIPIFEGITCLELANKSKNLKFMSNIVCQNSIDFTWRAGFTISFYECILCILFPFLILMQNKYTKDLKPLKLHRAQECQDYIEVRSMPYYKAKLKRFYMAPQTKFVIHSITFTSFLLYFSYVVLYGMRRMTLSTHETIFMSYLVILIFESIIEMFQSRSYSIFDRMKYWWKFNYCNKLDAIIILLAISAMALRYPLAYYPIDADIIIIYRCSKTIYSLIVGMLYIRFLRLLTRHKKLGPKMMMMTELVKQLMIYLIIIVIFLASYGVTSQAGYYLQRDFSWSALANLFQYPYYTMLGVIFSKYNVYLSWCDPAMNTTESKDCPEQNVVMPILFAAFVMISNILIMNILVATNCELCENIHKDSIDIWKYNKYSLLLEYEKKPIIPLPFSMIIHIYNILTDRCGESECYNLKNSK 1061
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Planmine SMEST
Match: SMESG000064632.1 (SMESG000064632.1) HSP 1 Score: 1288.48 bits (3333), Expect = 0.000e+0 Identity = 684/1090 (62.75%), Postives = 839/1090 (76.97%), Query Frame = 1
Query: 133 MIKRPSSKRTSQNEDYTVTIRQARCKINESCRESNVHFAENDEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKGLNDVKELLSKMIGFYEYPCS-ENDSIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINFFSCILCIIFPFLISKRTEFTKDFKTC---QSESFPDFNEDNCRTSISSKLRRFYVAPQTKXXXXXXXXXXXXXXXXYVVLYGMKRMQLTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKXXXXXXXXXXXXXXLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWCNASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNLSNSKKFEITKHNSKLHI 3390
M K P K++ N++++ +IRQAR KI +S R S++ F+ENDEK YR ++ + F S+ECR FS + +D N+KC CGE KK+HK +K P+ + W E + ME++ T SFGKIEF GEDITN+KLTDFVRVSY DKLDDI++L+FNKW I GTLCISVIGGTIDFKM KEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVK RNILE AKGRTVHYNVSNEVE++QP+SLNK+HTHYIF DDGYRLQM++KKV YFRQALENKISQK G+R IPVVLLIVEGGH++ +E SR AS+I+GE F+E+ + + RS ++ E+++ LK KLIEQ+I ELHQVDE +KCIE+I+K E LIT+F IKSH+DLDFAIL+SLIKRMD LCD NPLSSQLSLCL WNR+DIVKDKIF GDISLSN EW AF K+SI+ G++ FIELFLENVSN+ DFLT IL +LY+T PKS NFRKTFL LIGR FSKGL++ KEL+ KMIG ND HPFQELFLW+VLMEK KCA+FFWGKCD++L LALVATRIYK + TS+RDTDR TL WK FENLAVKLIEECHDIDQE AAYLIEK+ + GI+CLELA+KS +LKFMSNIVCQ SI+FTWRAGF I+F+ CILCI+FPFLI + ++TKD K +++ D+ E +KL+RFY+APQTKF IHS TF SF++YFSYVVLYGM+RM L+ HE +FM YLV++I + +E+F+SRS I+ R+KYWW FN+ NK+D III+ AI AM LRY LA + D ++++R SKTIYSLIVG Y++ LRLL HKKLGPK+ MM++++K+L+I+ II+IFL SYGVTSQAGYY QRDFSW AL+N+ YPYYTM GV+ VY +WC+ + N S +CPE N ++PILFA +V+I NIL++NIL+AT+ +C++IH +SI IWKY+ YSL+LEY KPI+P+PFS ++IY +L + CYNL N + + LH+
Sbjct: 1 MRKTPLKKQSFINDEFSASIRQARFKITDSNRGSHIRFSENDEKALYRKFVKSNFHSIECRKFSSLEEILDHNNAKCMCGEAKKNHKIDKTPFSLCDPWKENESMEVISTDSFGKIEFFGEDITNTKLTDFVRVSYNDKLDDILELLFNKWNINVGTLCISVIGGTIDFKMRKKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKKRNILESAKGRTVHYNVSNEVEQNQPVSLNKHHTHYIFVDDGYRLQMSRKKVAYFRQALENKISQKLGERAAIPVVLLIVEGGHEVLVEGSR----------------ASNILGEVFQEVSNSSWKRERTRSGDTSVFSENYRKALKTKLIEQNICELHQVDEDVKCIEEIVKKEFLITLFYIKSHQDLDFAILHSLIKRMDFLCDPRYNPLSSQLSLCLIWNRIDIVKDKIFLGDISLSNAEWIAFFKESIMKGRIDFIELFLENVSNLHDFLTTEILDDLYKTYPKSNNFRKTFLILIGRSFSKGLSEAKELVFKMIGVNRKQLKMRNDYSLHPFQELFLWSVLMEKNKCARFFWGKCDDALCLALVATRIYKCLRGTSVRDTDRQVTLTLWKESFENLAVKLIEECHDIDQETAAYLIEKEIPIFEGITCLELANKSKNLKFMSNIVCQNSIDFTWRAGFTISFYECILCILFPFLILMQNKYTKDLKPLKLHRAQECQDYIEVRSMPYYKAKLKRFYMAPQTKFVIHSITFTSFLLYFSYVVLYGMRRMTLSTHETIFMSYLVILIFESIIEMFQSRSYSIFDRMKYWWKFNYCNKLDAIIILLAISAMALRYPLAYYPIDADIIIIYRCSKTIYSLIVGMLYIRFLRLLTRHKKLGPKMMMMTELVKQLMIYLIIIVIFLASYGVTSQAGYYLQRDFSWSALANLFQYPYYTMLGVIFSKYNVYLSWCDPAMNTTESKDCPEQNVVMPILFAAFVMISNILIMNILVATNCELCENIHKDSIDIWKYNKYSLLLEYEKKPIIPLPFSMIIHIYNILTDRCGESECYNLKNKDEMMRYEQFPSLHM 1074
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Planmine SMEST
Match: SMESG000064637.1 (SMESG000064637.1) HSP 1 Score: 829.321 bits (2141), Expect = 0.000e+0 Identity = 427/757 (56.41%), Postives = 547/757 (72.26%), Query Frame = 1
Query: 163 SQNEDYTVTIRQARCKINESCRESNVHFAENDEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKGLNDVKELLSKMIGFYEYPCSEND-SIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINFFSCILCIIFPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISS---KLRRFYVAPQTK 2421
SQNE + + QAR ++ + + SNV+F NDEK + +I KF S++CR+F KE+ +K +KC CGE+K HK++KIPY WS C E +PT SFGKIEF GED+TN+KLT+FVR+S+ D LDD++ L+F+ W I GTLCISV+GGT +FKM KEK IF QGLIKA TTNALI+T GLN GIT +GDAIQ Q LYDK K NN + CLGIAPWG+VKN+ ILE AKG + Y VSNE+ +P+SLNKNHTHY+F D+ R + K FR+ALE K+SQ+ ++ IPVVLL++EG +D+F EAS+R+KE V IV+C GTG+ASD++GEAFREMQ+ K +R DGV MLPE ++N LK+KLI++++S +V+EA+ IE+II E LIT+FD+K DL+ AILYSLIKRMD DS N LSSQLSLCL WNRVDI KDKIFSG +SLS + WA FLK+SII GK +F+ELFL+N + + DFLT L++LYE CP+S N ++T +GR FS GL DVK+LL+K+ G+YE C+ D I HPFQELF+W+VLME +CA +FW K +ESL LALVAT+IYK S DT R ETL WK+YFENLA+KL+EECHD DQE AAY+IEK+N WGG +CLE+A K+ D KF+S +VCQ S++FTWRAGFNIN F CILCI PFLI +R+ F + +S+ D + T+ + KL +FY+APQTK
Sbjct: 13 SQNELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKY--PIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINLFQCILCIFLPFLIYRRS-FDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTK 766 HSP 2 Score: 247.284 bits (630), Expect = 2.320e-66 Identity = 173/496 (34.88%), Postives = 269/496 (54.23%), Query Frame = 1
Query: 2683 LRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKEXXXXXXXXXXXXXXYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTVYFTWC-NASTNYEVSNECPENNFLIPILFAGYVXXXXXXXXXXXXATSSYICQDIHGNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVLAFCYQKGRCYNL-----SNSKKFEITKHNSKLHIDKPMAFKHDTLNIFSNIKSDSDLNKLIKYFENYSQKFVIKNIAIEKQKSIKSGISRMEIRSKSIFKELENIQTK------------------------LNKIQIKNVKKVQEGSFTNTNGEYQNITKQPKDSMALLLTSLNNNILVLQDEVNRIGQEVNIVSTENSPVVITDNNCMESNISSSQRVIESISLNHNASNILFVMXXXXXXXXXXXXXXXXXXXAKELRNVHEKFDNFRNQTLNSLNNIELMMRKL 4080
LR+ L + D V+++R SKTIYSLIVG FYL+ LRL++ HK LGPKI M+SK++ +L+ + I+LI LL+YG+T Q Y+PQRDFS L NI+DYPY+ +FG + L VY WC + +TNY +SNECPE N+ +P+L A Y+ I ILLLNIL A +YI Q IH NSI IWK++M+SL++EY KP+ P+PFS F + AF + C N N K + +S++ P K + I +S+++KL+KYFEN SQK V+K + EK++ I+SG+SR+E R K++ +++I++K +++ +++N E NTN E + SL +++ Q V+ N+ S+ P +I D NC ++N S + L + + ++ + + E E++N+ +K +F++ + S IE ++ L
Sbjct: 784 LRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKMLYQLMFYIIIMLIILLAYGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQLVYLPWCDDKTTNYNISNECPELNYFVPVLTAIYIFIAAILLLNILTAVFNYIFQRIHRNSIEIWKFTMFSLVMEYYTKPLFPLPFSIFAH-----AFDFFYSLCGNQCEKTEENEKNLDTLSRDSQITFSPPKKMKSFNFRKLA-IPLESEIDKLVKYFENNSQKCVVKELVEEKEQLIESGMSRLESRLKAMSTIIKSIESKFEDSENPGNHNSAEMGNCYYPTLDISEFEVQNPTTFIEEDIINTNKE---------------IVSLIHDLRTGQLSVSAPSSNANVRSSFLIPRIIVDENC-DNNFSDPNSDLGGNKLKNWVTELINI----------------DSETVLEVQNLQKKLCDFQDHVVESFTKIESFLQSL 1241
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Planmine SMEST
Match: SMESG000064637.1 (SMESG000064637.1) HSP 1 Score: 825.083 bits (2130), Expect = 0.000e+0 Identity = 427/757 (56.41%), Postives = 547/757 (72.26%), Query Frame = 1
Query: 163 SQNEDYTVTIRQARCKINESCRESNVHFAENDEKMQYRNYINAKFKSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRNILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDXXXXXXXXXXXXXXTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKGLNDVKELLSKMIGFYEYPCSEND-SIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQKSIEFTWRAGFNINFFSCILCIIFPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISS---KLRRFYVAPQTK 2421
SQNE + + QAR ++ + + SNV+F NDEK + +I KF S++CR+F KE+ +K +KC CGE+K HK++KIPY WS C E +PT SFGKIEF GED+TN+KLT+FVR+S+ D LDD++ L+F+ W I GTLCISV+GGT +FKM KEK IF QGLIKA TTNALI+T GLN GIT +GDAIQ Q LYDK K NN + CLGIAPWG+VKN+ ILE AKG + Y VSNE+ +P+SLNKNHTHY+F D+ R + K FR+ALE K+SQ+ ++ IPVVLL++EG +D+F EAS+R+KE V IV+C GTG+ASD++GEAFREMQ+ K +R DGV MLPE ++N LK+KLI++++S +V+EA+ IE+II E LIT+FD+K DL+ AILYSLIKRMD DS N LSSQLSLCL WNRVDI KDKIFSG +SLS + WA FLK+SII GK +F+ELFL+N + + DFLT L++LYE CP+S N ++T +GR FS GL DVK+LL+K+ G+YE C+ D I HPFQELF+W+VLME +CA +FW K +ESL LALVAT+IYK S DT R ETL WK+YFENLA+KL+EECHD DQE AAY+IEK+N WGG +CLE+A K+ D KF+S +VCQ S++FTWRAGFNIN F CILCI PFLI +R+ F + +S+ D + T+ + KL +FY+APQTK
Sbjct: 13 SQNELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKY--PIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINLFQCILCIFLPFLIYRRS-FDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTK 766 The following BLAST results are available for this feature:
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002539 ID=SMED30002539|Name=Transient receptor potential cation channel subfamily M member 6|organism=Schmidtea mediterranea sexual|type=transcript|length=4112bpback to top protein sequence of SMED30002539-orf-1 >SMED30002539-orf-1 ID=SMED30002539-orf-1|Name=SMED30002539-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1317bp MIKRPSSKRTSQNEDYTVTIRQARCKINESCRESNVHFAENDEKMQYRNYback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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