Ubiquitin carboxyl-terminal hydrolase

Query:   20 ACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI-----------------------FRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISSKQ-----------TDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             CSHL  F +    K  ++ +    V+  + +  K KA S IC  C  H   L+    C +C+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  E I KE +R  +    + +   +W P  ++L LLK+  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD HRC  ++   +CL CEM  + QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++                         +G+ +L    R +   E +  +    CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S +           TD    ++KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L
Sbjct:   22 GCSHLGSF-KVDNWKQNLRAIYQCFVWSGTAEARKRKAKSCICHVCGVH---LNRLHSCLYCVFFGCFTKKHIHEHAKAKRHNLAIDLMYGGIYCFLCQDYIYDKDMEIIAKEEQRKAWKMQGVGEKFSTWEPTKRELELLKH-NPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRC-EMQSPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFL 522          

Query:  134 SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI-----------------------FRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISSKQ-----------TDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
            S IC  C  H   L+    C +C+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  E I KE +R  +    + +   +W P  ++L LLK+  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD HRC  ++   +CL CEM  + QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++                         +G+ +L    R +   E +  +    CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S +           TD    ++KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L
Sbjct:   48 SCICHVCGVH---LNRLHSCLYCVFFGCFTKKHIHEHAKAKRHNLAIDLMYGGIYCFLCQDYIYDKDMEIIAKEEQRKAWKMQGVGEKFSTWEPTKRELELLKH-NPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRC-EMQSPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFL 510          

Query:   20 ACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFR----RLY-----------FANFAMFDLSWRPEIKD---LHLLKYVTPLESSLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRN-----------------------GSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKR----CHANSKVNTKVDFPEELDLAPFISSKQ----------TDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             CSH+  F   +  +  ++ +    V+  + +  K KA S IC  C+ H + L     C  C+F  C   KHI  H   K H + V L  G +YC  C+DY Y +  EQI KE +    RL            F      D     E K+     +       + S+     RGL+N+GNTCF+N ++QALTH P L+DF LSD H+C     S  CL CEM  +   +Y     P+    LL++IW   + LAGY Q DAHE  +AIL +LH H  ++++          Q   +P+C                   C+CI+ Q F   L+S +        S  ++   D+SL++  +                       G  SL    + +   E +  +    C++C     +TKQ ++ +LP +   HLKR         K+NT + FP ELD+ PF++S +          TD    E+KYSL++VINH G   SGHYT ++R + + W  CDD  +    I ++L S+ Y+LFYHK  L
Sbjct:  194 GCSHVESFKVGKNWQKNLRLIYQRFVWSGTPETRKRKAKSCICHVCSTHMNRLHS---CLSCVFFGCFTEKHIHKHAETKQHHLAVDLYHGVIYCFMCKDYVYDKDIEQIAKETKEKILRLLTSTSTDVSHQQFMTSGFEDKQSTCETKEQEPKLVKPKKKRRKKSVYTVGLRGLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHKCIMTSPSL-CLVCEMSSLFHAMYSGSRTPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHRH--SKDDSGG-------QEANNPNC-------------------CNCIIDQIFTGGLQSDVTCQACHSVSTTIDPCWDISLDLPGSCATFDSQNPERADSTVSRDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTMKKLPIVACFHLKRFEHVGKQRRKINTFISFPLELDMTPFLASTKESRMKEGQPPTDCVPNENKYSLFAVINHHGTLESGHYTSFIRQQKDQWFSCDDAIITKATIEDLLYSEGYLLFYHKQGL 708          

Query:  308 CQDYQYHEYSEQIIKE-----------------FRRLYFANFAMFDLSWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI------------FRNGSVSLEAS----------FRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKR----CHANSKVNTKVDFPEELDLAPFISSKQ-----------TDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSLVMKS 1492
            C+DY Y +  EQI KE                  ++           +W     +L LL +  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD HRC  +     CL CEM  + +E+Y     P+    LL+++W   + LAGY Q DAHE  +A L +LH H                       C  D +  ++ +      + C+CI+ Q F   L+S +        S  ++   D+SL++             R  SV+ E+            R +   E +  +    C +C     +TKQ ++ +LP +   H KR         K+ T + FP ELD+ PF++S +           T+    E+KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L  +S
Sbjct:    2 CKDYVYDKDIEQIAKEEQGEALKLQASTSTEVSHQQCSVPGLGEKFPTWETTKPELELLGH-NPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRC-EMPSPELCLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRH-----------------------CKGDDVGKAANNP-----NHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFYHKQVLEHES 427          

Query:  479 RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRN-----------------------GSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKR----CHANSKVNTKVDFPEELDLAPFISSKQ----------TDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
            RGL+N+GNTCF+N ++QALTH P L+DF LSD H+C     S  CL CEM  +   +Y     P+    LL++IW   + LAGY Q DAHE  +AIL +LH H  ++++          Q   +P+C                   C+CI+ Q F   L+S +        S  ++   D+SL++  +                       G  SL    + +   E +  +    C++C     +TKQ ++ +LP +   HLKR         K+NT + FP ELD+ PF++S +          TD    E+KYSL++VINH G   SGHYT ++R + + W  CDD  +    I ++L S+ Y+LFYHK  L
Sbjct:   82 RGLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHKCIMTSPSL-CLVCEMSSLFHAMYSGSRTPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHRH--SKDDSGG-------QEANNPNC-------------------CNCIIDQIFTGGLQSDVTCQACHSVSTTIDPCWDISLDLPGSCATFDSQNPERADSTVSRDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTMKKLPIVACFHLKRFEHVGKQRRKINTFISFPLELDMTPFLASTKESRMKEGQPPTDCVPNENKYSLFAVINHHGTLESGHYTSFIRQQKDQWFSCDDAIITKATIEDLLYSEGYLLFYHKQGL 427          

Query:  479 RGLVNMGNTCFLNVVIQALTHTPALRDFLLS------DLHRCPTVKQSRN-CLACEMIR--ITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIF--RNGS-VSLEASFRSYFGTERMKDAL---CSTC-LKLGATKQYSLFQLPNIFSVHLKRCHANSKVNTK-VDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQN-SSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHK 1471
            RG+ N+GNTCF+N V+QAL      R++++S       +H     K   N C   +  R  +  +  +    P A +       S      G+ QHD+HE     +  LH        ++ + R L                        G+ DD    + + F  TL+S ++     + S  ++ F DLSL+I   RN S V L     ++F  E ++      C+ C  K   +KQ  + +LP +  +H+KR   N   N   +DFP  +LD+  F++    +       YSL S+I H G    SGHY  + +     W   DD  V  V    V +  AY+L Y K
Sbjct:  229 RGMRNVGNTCFMNAVLQALASISEFREYIMSLSSLEDYIHDEKEPKNGGNYCYLTDEYRKLLISQSARSFREPTAPNEFREAFISVCPRFRGFRQHDSHEFMRYFMDSLHT-------EMRKCRKL-----------------------PGMPDDKHTPISKYFEGTLQSSVICQTCRNCSNKIDEFMDLSLDIPAQRNASKVRLSDCLSTFFKLEMLEKGEKPECAKCKTKQTCSKQMFIRKLPQVLCLHMKRFRDNGGKNDAIIDFPMGQLDVTQFLTDDSDEAPCT---YSLQSIIVHIGYGCGSGHYIAFGKRNGR-WFQFDDTVVKGVDEAHVSKQKAYVLLYTK 544          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSR----NCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQV-QDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCS------QDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKDALCSTCLK----LGATKQYSLFQLPNIFSVHLKR---CHANSKVNT-KVDF-PEELDLAPFI-SSKQTDKSLWEDKYSLYSVINHRGQNSSGHYT-VYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHK 1471
            GL NMGNTCF++  +Q L  TP L +     +       QSR      ++     ++  I+         S  L +    V Q L+   QHDA E  + +L  LH   +  +    E        +A  +        Q +++  +R   +    +  C+   A  AT E   +                +S+EI  N S SL+   RS+F   ++       C K      +T+   L+Q P +  +HLKR    + + + NT  V F     D+ P++      +K +    Y LY+   H G+ +SGHYT V     ++ W   DD  V      +V  S AY+LFY +
Sbjct:  479 GLFNMGNTCFMSATLQCLFQTPGLAEVFTKKVFVSKVNTQSRLGSKGVISAGFASLSDMIWNGTFTAIRPSRFLQLFSDTVYQPLSDGRQHDASEFQIFLLDALHEDTNQAQRISFEQNYHGGAGIAKEAADFLKKHYQFSLSPVNRLLGSITVSEIRCLTCGASSATFEENTI----------------ISVEIPSNSSCSLDMCLRSHFSQTKLDGDSRWNCPKCKEPRASTRTSKLWQPPPVMIIHLKRFALFNGDFEKNTAAVTFETARFDVRPYLHEMAPAEKPV----YKLYAATLHNGRLNSGHYTAVASHLRSDKWLRFDDSVVTPCENFKVDPSLAYILFYKR 810          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSR----NCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQV-QDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCS------QDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKDALCSTCLK----LGATKQYSLFQLPNIFSVHLKR---CHANSKVNT-KVDF-PEELDLAPFI-SSKQTDKSLWEDKYSLYSVINHRGQNSSGHYT-VYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHK 1471
            GL NMGNTCF++  +Q L  TP L +     +       QSR      ++     ++  I+         S  L +    V Q L+   QHDA E  + +L  LH   +  +    E        +A  +        Q +++  +R   +    +  C+   A  AT E   +                +S+EI  N S SL+   RS+F   ++       C K      +T+   L+Q P +  +HLKR    + + + NT  V F     D+ P++      +K +    Y LY+   H G+ +SGHYT V     ++ W   DD  V      +V  S AY+LFY +
Sbjct:  479 GLFNMGNTCFMSATLQCLFQTPGLAEVFTKKVFVSKVNTQSRLGSKGVISAGFASLSDMIWNGTFTAIRPSRFLQLFSDTVYQPLSDGRQHDASEFQIFLLDALHEDTNQAQRISFEQNYHGGAGIAKEAADFLKKHYQFSLSPVNRLLGSITVSEIRCLTCGASSATFEENTI----------------ISVEIPSNSSCSLDMCLRSHFSQTKLDGDSRWNCPKCKEPRASTRTSKLWQPPPVMIIHLKRFALFNGDFEKNTAAVTFETARFDVRPYLHEMAPAEKPV----YKLYAATLHNGRLNSGHYTAVASHLRSDKWLRFDDSVVTPCENFKVDPSLAYILFYKR 810          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKDALCSTCLKLG-ATKQYSLFQLPNIFSVHLKR----CHANSKVNTKVDFPEELDLAPFISSKQTDKSLWE--DKYSLYSVINHRGQNSS-GHYTVYVRTEAN-IWCLCDDQNVHHVP 1423
            GL+N GN C++N  +Q   + P  R  +          + S N +  E  R+  +     +   AL ++ Y + +       +N+ D       +L L      ++E  +    +L+        C  D  NG                +   F     ++IV  CG  + R  E    L+L I   G  +L  +  +YFG E + D  CS C K G  +KQ    +LP +  + L R         K+ T + +P E+    F   ++T+ S+    + Y L++V  H G N+  GHY   +++  N  W   +D+ V  +P
Sbjct:  109 GLINGGNFCYVNSFLQVWFNVPEFRQLIYD-------FRPSENFVPPEAPRMNVQ-----ATMLALQDIFYTLQT-----TPFNETDKTSNLGKLLRLNSEQQDSQEFGLKFFNALE-------RCLPDHPNGKETLKR----------LKDLFTGETCTRIVCKCGQRSERE-ETAISLTLNI--EGYCTLLDALDAYFGEEHLDDFKCSKCNKTGDVSKQSDYVKLPPVIVIQLNRYKYTSKGRQKLKTPMAYPREIPAKAF---QRTNNSIPPPAEMYDLFAVTIHEGNNAECGHYYDLIKSPLNQKWYRYNDETVEAIP 391          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLS-DLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKI-VYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKDALCSTCLKLG---ATKQYSLFQLPNIFSVHLKR---CHANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDK--YSLYSVINHRGQNSSGHYTVYVR----------TEANIWCLCDDQNVHHVPITEV----------LQSDAYMLFYHKNSLV 1483
            GL N G TC++N ++Q+   T   R  + + D+   P   +S   LA  M R+  E+          S      W +   L  +NQHD  E    +L  L   +                             G+S   S          +   F   ++S I   D    +SR  E F D+ L +   G  SLE +F +Y  +E + D         G   A K     +LP I  V L R   C    K+N +  FPE+++LA   S  +    L E+   YSL++V+ H G+   GHY  Y+           T +  WC  DD  V      +           + S AYML Y +++ +
Sbjct:  194 GLRNQGATCYMNSILQSFYFTTGFRRAVYNMDVGTEPN--ESNIVLA--MQRVFYELQMASEAVETNSLTRAFGWDK---LDAFNQHDVQEFCRVLLDNLETKMK----------------------------GTSEEKS----------IPNLFRGNMKSYIKCLDVDYESSR-TESFYDVQLNVL--GMDSLERAFEAYTTSEILDDENKYDAGDHGLQRAEKGVKFVELPPILHVQLMRFQYCGVEQKINERFSFPEKMNLA---SCCELGPMLTEEDCVYSLHAVLVHSGEFHGGHYVTYINVNLHESAVDPTSSAKWCKFDDDVVSRTTTDDAIVSNFGGEKTMNSSAYMLVYVRDNAI 506          

Query:  188 VCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANF--AMFDLSWRPEIKDLHLL------KYVTPLESSLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSL---EIFRNGSV---SLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANS----KVNTKVDFPEELDLAPFISSKQTDKSLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             C HCI+  CR   HI  H R K H + + L  G +YC  C+D+ Y   S +     R+L   +   ++  + W P  K+ +LL      + V P ++       RGL+N+G TCF+N ++QAL HTP L D+ +SD H C + K S  CL CE+ R+ QE Y     P +L  LL++IW+  + LAGY Q DAHE F+A L +LH H          +++         S    +   SS SSS+     C+CI+ Q F   L+S +V       S   + F D+SL   E   +G V   +L      Y   E +  A    CSTC     +TKQ+SL  LP++ S HLKR   ++    K+++ + FP E D+ PF+S K   K+ + D ++SLY+V+NH G   +GHYT YVR + + W  CDD  +    + +VL S+ Y+LFYHKN L
Sbjct:   58 ACLHCIYFGCR-GAHITSHLRSKKHNVALELSHGTLYCYACRDFIYDARSREYALINRKLEAKDLQKSIGWVPWVPTTKETNLLLANARRRLVRPNQTI----GLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGS-KSSHKCLVCEVSRLFQEFYSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHC---------VKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPVEFDMTPFMSEK---KNAYGDFRFSLYAVVNHVGTIDTGHYTAYVRHQKDTWVKCDDHVITMASLKQVLDSEGYLLFYHKNVL 493          

Query:  188 VCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANF--AMFDLSWRPEIKDLHLL------KYVTPLESSLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSL---EIFRNGSV---SLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANS----KVNTKVDFPEELDLAPFISSKQTDKSLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             C HCI+  CR   HI  H R K H + + L  G +YC  C+D+ Y   S +     R+L   +   ++  + W P  K+ +LL      + V P ++       RGL+N+G TCF+N ++QAL HTP L D+ +SD H C + K S  CL CE+ R+ QE Y     P +L  LL++IW+  + LAGY Q DAHE F+A L +LH H          +++         S    +   SS SSS+     C+CI+ Q F   L+S +V       S   + F D+SL   E   +G V   +L      Y   E +  A    CSTC     +TKQ+SL  LP++ S HLKR   ++    K+++ + FP E D+ PF+S K   K+ + D ++SLY+V+NH G   +GHYT YVR + + W  CDD  +    + +VL S+ Y+LFYHKN L
Sbjct:   58 ACLHCIYFGCR-GAHITSHLRSKKHNVALELSHGTLYCYACRDFIYDARSREYALINRKLEAKDLQKSIGWVPWVPTTKETNLLLANARRRLVRPNQTI----GLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGS-KSSHKCLVCEVSRLFQEFYSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHC---------VKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPVEFDMTPFMSEK---KNAYGDFRFSLYAVVNHVGTIDTGHYTAYVRHQKDTWVKCDDHVITMASLKQVLDSEGYLLFYHKNVL 493          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHR--CPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSV-SLEASFRSYFGTERMKDALCSTC-LKLGATKQYSLFQLPNIFSVHLKRCHANS-------KVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANI--WCLCDDQNVHHVPITEVLQSDAYMLFY 1465
            GL N+GNTC++N ++Q L++TP L ++ +SD ++       ++   +  E+  + +E++       A  +L YV+    +   G +Q D+HE    ++  LH+               D+Q L  P   ++ I+ S ++     +     I+H  F   ++S +        S   E F +LSLE+  N +V  L      YF  ER+    C +C  K  A K+  + +LP +  VHLKR +A+        K    + FP E LD+ P+I+  ++ +++    Y LY+V NH G    GHYT + ++ AN   W   DDQ V  +  + V+ S AY+LFY
Sbjct:   35 GLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKTNGQVIEEVAALIKELWNGQYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHS---------------DLQTLHVPR-QREMISASEKAWLEFTKAKESMILH-LFYGQMKSTVKCVACHKESATYESFSNLSLELPPNSNVCQLNQCMDMYFSGERIHGWNCPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGSYMKKQNYLRFPLENLDMNPYIARAES-RAVTPKTYQLYAVSNHYGTMEGGHYTAFCKS-ANYGKWFKFDDQVVSALDSSNVVSSAAYILFY 357          

Query:  374 ANFAMFDLSWRPEIKDL----HLLKYVTPLESSLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHR--CPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSV-SLEASFRSYFGTERMKDALCSTC-LKLGATKQYSLFQLPNIFSVHLKRCHANS-------KVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANI--WCLCDDQNVHHVPITEVLQSDAYMLFY 1465
            A    FD + +P+ +++      ++  +P+      +   GL N+GNTC++N ++Q L++TP L ++ +SD ++       ++   +  E+  + +E++       A  +L YV+    +   G +Q D+HE    ++  LH+               D+Q L  P   ++ I+ S ++     +     I+H  F   ++S +        S   E F +LSLE+  N +V  L      YF  ER+    C +C  K  A K+  + +LP +  VHLKR +A+        K    + FP E LD+ P+I+  ++ +++    Y LY+V NH G    GHYT + ++ AN   W   DDQ V  +  + V+ S AY+LFY
Sbjct:  524 AEIPTFDRAMKPQPRNVERTSQRVRDFSPVIGQNVGRGLTGLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKTNGQVIEEVAALIKELWNGQYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHS---------------DLQTLHVPR-QREMISASEKAWLEFTKAKESMILH-LFYGQMKSTVKCVACHKESATYESFSNLSLELPPNSNVCQLNQCMDMYFSGERIHGWNCPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGSYMKKQNYLRFPLENLDMNPYIARAES-RAVTPKTYQLYAVSNHYGTMEGGHYTAFCKS-ANYGKWFKFDDQVVSALDSSNVVSSAAYILFY 886          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSD---LHRCPTVKQSRNCLACEMIRI------TQEIYKPVSVPYALSNLLYVIWSQVQDLAGY----NQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKDA--LCSTC-LKLGATKQYSLFQLPNIFSVHLKR-CHANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSS-GHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFY 1465
            G++N+GNTC+LN  +QAL H PAL ++L+S+   L  C   +    C+ C M +        Q   +P           ++I+S+++ +  +     Q DAHE    ++  +      R     E+  L  +                              + Q F   L S++      H S   + F+DL L+I +  + SLE +F  +F  ER++D    C  C  K+ ATKQ+SL + P    + LKR     +K+  ++ F   +DL+ + +  Q  ++     Y L S++ H G +   GHYT    T+   +   DD  V  + +  V  ++AY++F+
Sbjct:  103 GMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNVAEPGSGCIICAMTKTLLATQSNQSAVRP-----------FLIYSKLKQICKHMVVGRQEDAHEFLRFLVEAMERAYLMRFRNYKELDQLVKETTP---------------------------LGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDIRK--ADSLEDAFEGHFSRERLEDMGYKCEGCKKKVSATKQFSLERAPITLCIQLKRFSMIGNKLTKQISFKSRIDLSKYAARSQAAQAQ-PLTYRLVSMVTHLGASQHCGHYTAIGSTDTGSFYNFDDSYVRPIAMHSVCNTNAYIMFF 407          

Query:   20 ACSHLNIF-FENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI-----------------------FRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISS----------KQTDKSLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             CSH+N F  +N    L V  +    V+  S +  K KA S IC  C  H   L+    C HC+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  EQI KE +R  +    + +    W P  ++L LL++  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD H+C    QS +CL CEM ++ QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H                       C  D  NG   ++     + C+CI+ Q F   L+S +        S  ++ F D+SL++                         +G+ +L    R +   E +  +    CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S          +Q   SL  D KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L
Sbjct:    5 GCSHVNGFKVDNWKQNLRV--IYQCFVWSGSAETRKRKAKSCICHMCGAH---LNRLHSCLHCVFFGCFSKKHIHEHAKNKRHNLAIDLLYGGIYCFVCQDYIYDKDMEQIAKEEQRKAWKLQGIGEKYSMWEPTKRELELLRH-NPKRRKITANCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKCEM--QSNSCLVCEMSQLFQEFYSGHRSPHIPFRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRH-----------------------CKDD--NGKKANNP----NHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSDGSVVNGDSHPSGATTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKRLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPVDSLNNDNKYSLFAVVNHQGTLESGHYTTFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFL 503          

Query:  134 SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI-----------------------FRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISS----------KQTDKSLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
            S IC  C  H   L+    C HC+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  EQI KE +R  +    + +    W P  ++L LL++  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD H+C    QS +CL CEM ++ QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H                       C  D  NG   ++     + C+CI+ Q F   L+S +        S  ++ F D+SL++                         +G+ +L    R +   E +  +    CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S          +Q   SL  D KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L
Sbjct:    3 SCICHMCGAH---LNRLHSCLHCVFFGCFSKKHIHEHAKNKRHNLAIDLLYGGIYCFVCQDYIYDKDMEQIAKEEQRKAWKLQGIGEKYSMWEPTKRELELLRH-NPKRRKITANCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKCEM--QSNSCLVCEMSQLFQEFYSGHRSPHIPFRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRH-----------------------CKDD--NGKKANNP----NHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSDGSVVNGDSHPSGATTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKRLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPVDSLNNDNKYSLFAVVNHQGTLESGHYTTFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFL 463          

Query:   20 ACSHLNIF-FENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI-----------------------FRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLK 1189
             CSH+N F  +N    L V  +    V+  S +  K KA S IC  C  H   L+    C HC+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  EQI KE +R  +    + +    W P  ++L LL++  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD H+C    QS +CL CEM ++ QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++                         +G+ +L    R +   E +  +    CS C     +TKQ ++ +LP +   HLK
Sbjct:    5 GCSHVNGFKVDNWKQNLRV--IYQCFVWSGSAETRKRKAKSCICHMCGAH---LNRLHSCLHCVFFGCFSKKHIHEHAKNKRHNLAIDLLYGGIYCFVCQDYIYDKDMEQIAKEEQRKAWKLQGIGEKYSMWEPTKRELELLRH-NPKRRKITANCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKCEM--QSNSCLVCEMSQLFQEFYSGHRSPHIPFRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSDGSVVNGDSHPSGATTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKRLPIVACFHLK 392          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVK--QSRNCLACEMIRITQEIYKPVS-VPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIV-YDCGVHTSRHLEIFRDLSLEIFR-NGSVSLEASFRSYF------GTERMKDALCSTCLKLGATKQYSLFQLPNIFSVHLKR---CHA-NSKVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTE-ANIWCLCDDQNVHHVPITEVLQSDAYMLFYH 1468
            GL N+GNTCF+N ++Q L++T  LRD+ L + HR       +++  L  E  ++TQ I+   S    + S+    I        GYNQ DA E    +L  LHN ++ R    +     D+  L++    +   N    S  + V D         F+  L+S +   +CG   S   + F DLSL I + +G VSL    R +       G ER     C T  K   TK++++ + P I  +HLKR   C    SK++T V+FP +ELDL  F S    +       Y+LY+V NH G +  GHYT Y R+     W   +D  V  +  ++V  SDAY+LFY 
Sbjct:   63 GLRNLGNTCFMNSILQCLSNTHDLRDYCLRNTHRTDLNNNCRAKAALMDEFAKLTQTIWTSASNEAISPSDFKMQIQKYAPRFVGYNQQDAQEFLRFLLDGLHNEVN-RVTVKSRAPVEDLDHLSEDEKGKRMWNKYLESEDSKVVD--------LFVGQLKSSLTCSECGF-CSTVFDPFWDLSLPIAKTSGEVSLNDCLRLFTKEDVLDGNERPTCHRCKTRRK--CTKKFTIQKFPKILVLHLKRFSECRVRTSKLSTFVNFPLKELDLREFASDNSVNAV-----YNLYAVSNHTGTSLGGHYTAYCRSPCTGEWYTYNDSRVSPMSSSQVCSSDAYVLFYE 391          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSR--NCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLA----GYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIV-YDCGVHTSRHLEIFRDLSLEIFRN-GSVSLEASFRSYFGTERMKDALCSTCLKLGA----TKQYSLFQLPNIFSVHLKRCHA----NSKVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVY-VRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
            GL N+GNTCF+N ++Q L++T +LRD+ L + HR      +R    L  E  ++ Q ++   +   + +       +Q+Q  A    GYNQ DA E    +L  LH       N+VN +         D     D   G    S     +D   +    F+  L+S +   +CG + S   + F DLSL I +  G VSL    R +   + +      TC +  A    TK++++ + P I  +HLKR        SK++T V+FP ++LDL  F S + +        Y+LY+V NH G    GHYT Y    E   W   +D  V  +  ++V  SDAY+LFY +  L
Sbjct:   62 GLRNLGNTCFMNSILQCLSNTQSLRDYCLHNSHRRDLNNNNRTHTALMEEFAKLIQTMW---TSSSSEAVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLH-------NEVNRVTVRPRGNTEDFDHLPDEEKGKKMWSKYLEREDSKIV--DLFVGQLKSSLTCSECG-YCSTVFDPFWDLSLPIAKGYGEVSLMDCMRLFTKEDVLDGDEKPTCYRCKARRRCTKKFTVQKFPKILVLHLKRFSEARIRTSKLSTFVNFPMKDLDLREFASDRSSSAV-----YNLYAVSNHSGTTMGGHYTAYCCNPENGEWYTYNDSRVTPMSASQVRSSDAYVLFYERAGL 394          

Query:   20 ACSHLNIF-FENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFA------------NFAMFDL-----SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI---------FRNGSVSLEASFRSYF-GTERMKDAL----------------CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISS----------KQTDKSLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             CSH+N F  EN    L V  +    V+  + +  K KA S IC  C  H   L+    C +C+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  EQ+ KE +R  +              +AM  +     +W P  ++L LL++  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD H+C  ++   +CL CEM  + QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++            GS S   +  S+  GT  + D L                CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S          +Q   SL  D KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L
Sbjct:   54 GCSHVNSFKVENWKQNLRV--IYQCFVWSGTPETRKRKAKSCICHMCGAH---LNRLHSCLYCVFFGCFTKKHIHEHAKNKRHNLAIDLLYGGIYCFMCQDYIYDKDMEQVAKEEQRKAWKLQAFSPALVSPYQYAMTGVGEKYSTWEPTKRELELLQH-NPKRRKITTNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKC-EMQSPNSCLVCEMSTLFQEFYSGHRSPHIPYRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSDSAVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPSDSLHNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFL 569          

Query:   20 ACSHLNIF-FENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI---------FRNGSVSLEASFRSYF-GTERMKDAL----------------CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISS----------KQTDKSLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDA 1450
             CSH+N F  EN    L V  +    V+  + +  K KA S IC  C  H   L+    C +C+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  EQ+ KE +R  +    + +   +W P  ++L LL++  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD H+C  ++   +CL CEM  + QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++            GS S   +  S+  GT  + D L                CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S          +Q   SL  D KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ 
Sbjct:    5 GCSHVNSFKVENWKQNLRV--IYQCFVWSGTPETRKRKAKSCICHMCGAH---LNRLHSCLYCVFFGCFTKKHIHEHAKNKRHNLAIDLLYGGIYCFMCQDYIYDKDMEQVAKEEQRKAWKLQGVGEKYSTWEPTKRELELLQH-NPKRRKITTNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKC-EMQSPNSCLVCEMSTLFQEFYSGHRSPHIPYRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSDSAVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPSDSLHNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEG 495          

Query:   20 ACSHLNIF-FENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI---------FRNGSVSLEASFRSYF-GTERMKDAL----------------CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISS----------KQTDKSLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDA 1450
             CSH+N F  EN    L V  +    V+  + +  K KA S IC  C  H   L+    C +C+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  EQ+ KE +R  +    + +   +W P  ++L LL++  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD H+C  ++   +CL CEM  + QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++            GS S   +  S+  GT  + D L                CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S          +Q   SL  D KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ 
Sbjct:   23 GCSHVNSFKVENWKQNLRV--IYQCFVWSGTPETRKRKAKSCICHMCGAH---LNRLHSCLYCVFFGCFTKKHIHEHAKNKRHNLAIDLLYGGIYCFMCQDYIYDKDMEQVAKEEQRKAWKLQGVGEKYSTWEPTKRELELLQH-NPKRRKITTNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKC-EMQSPNSCLVCEMSTLFQEFYSGHRSPHIPYRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSDSAVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPSDSLHNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEG 513          

Query:  308 CQDYQYHEYSEQIIKEFRRLYF-------ANFAMFDL-----SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI---------FRNGSVSLEASFRSYF-GTERMKDAL----------------CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISS----------KQTDKSLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFY 1465
            CQDY Y +  EQ+ KE +R  +           M  +     +W P  ++L LL++  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD H+C  ++   +CL CEM  + QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++            GS S   +  S+  GT  + D L                CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S          +Q   SL  D KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+  Y
Sbjct:    2 CQDYIYDKDMEQVAKEEQRKAWKLQGRCSVPTQMVPIGEKYSTWEPTKRELELLQH-NPKRRKITTNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKC-EMQSPNSCLVCEMSTLFQEFYSGHRSPHIPYRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSDSAVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPSDSLHNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLQIY 414          

Query:  308 CQDYQYHEYSEQIIKEFRRLYFANFAMFDL--------------SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI---------FRNGSVSLEASFRSYF-GTERMKDAL----------------CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISS----------KQTDKSLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDA 1450
            CQDY Y +  EQ+ KE +R  +       +              +W P  ++L LL++  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD H+C  ++   +CL CEM  + QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++            GS S   +  S+  GT  + D L                CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S          +Q   SL  D KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ 
Sbjct:    2 CQDYIYDKDMEQVAKEEQRKAWKLQGSSKVNHLWKCLGVGEKYSTWEPTKRELELLQH-NPKRRKITTNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKC-EMQSPNSCLVCEMSTLFQEFYSGHRSPHIPYRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSDSAVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPSDSLHNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEG 411          

Query:   20 ACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI-----------------------FRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISSKQTDK----------SLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             CSHL  F +    K  ++ +    V+  + +  K KA S +C  C  H   L+    C +C+F  C   KHI DH + K H + + L  G +YC  CQDY Y +  E I KE +R  +    + +   +W P  ++L LLK+  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD HRC  ++   +CL CEM  + QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++                         +G+ +L    R +   E +  +    CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S +  +          SL  D KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L
Sbjct:   22 GCSHLGSF-KVDNWKQNLRAIYQCFVWSGTAEARKRKAKSCVCHVCGIH---LNRLHSCLYCVFFGCFTKKHIHDHAKSKRHNLAIDLMYGGIYCFLCQDYIYDKDIEIIAKEEQRKAWKMQGVGEKFSTWEPTKRELELLKH-NPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRC-EMQSPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSEGSVVNGESHASGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPLDSLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFL 522          

Query:   20 ACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRR--LYFANFAMFDLSWR----PEIKDLHLLKYVTPLESSLDCKPT-------------RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI--------------FRNGS----VSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKR----CHANSKVNTKVDFPEELDLAPFISSKQ---------TDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             C H+  F   +  +  ++ +    ++  + +  K KA S IC+ C+ HK+ L     C  C+F  C  +KHI  H     H + V L  G +YC  C+DY Y +  E+I KE +   L   +    D S++     E+++  L       E+SL                  RGL+N+GNTCF+N ++Q LTH P L++F LS+ H+C     S  CL CEM  + Q +Y     P+    LL++IW   + LAGY Q DA E  +AIL +LH H  +R++ +++                            G  + C+CI+   F  +L+S +        S  ++   D+SL++               R+G     +SL    + +   E +  +    CS C     +TKQ ++ +LP +   HLKR         K+N+ + FP ELD+ PF++S +         T+    E+KYSL++VINH G   SGHYT +VR E + W  CDD  V    + E+L S+ Y+LFYH+  +
Sbjct:  150 GCCHVESFKVAKNWQRNLRMIYQRFIWSGTPETRKRKAKSCICQICSTHKNRLHS---CLSCVFFGCFTDKHIHIHAETTQHNLAVDLCHGVIYCFMCRDYVYDKDIEKIAKETKEKILGLLSSPTGDASYQQLMASEVEENQLTCESKDQETSLVKPKKKRRKKTMYYTVGFRGLINLGNTCFMNCIVQVLTHIPLLKEFFLSNKHKCMMTSPSL-CLVCEMSLLFQAMYSGNQSPHIPYKLLHLIWIHAEHLAGYRQQDAQEFLIAILDVLHRH--SRDDGIDQ---------------------------EGNSNCCNCIIDHIFTGSLQSDLTCQVCHGVSTTIDPCWDISLDLPGPYTPGRASSSTSSRDGQKPRVISLTDCLKWFTRPEDLGSSAKIKCSQCQSYQESTKQLTMKKLPIVACFHLKRFEHLGKQRRKINSFISFPLELDMTPFLASTKESIMKGQPLTECVPSENKYSLFAVINHHGTLESGHYTSFVRQEKDQWFSCDDAVVTKATMEELLNSEGYLLFYHRQDI 658          

Query:  479 RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI------FRNGSVSLEASFRS---YFGTERMKDAL----------------CSTCLKLG-ATKQYSLFQLPNIFSVHLKR----CHANSKVNTKVDFPEELDLAPFISSKQ-----------TDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSLVMKS-N*RTIIPQNY 1522
            RGL+N+GNTCF+N ++QALTHTP LRDF LSD HRC  +     CL CEM  + +E+Y     P+    LL+++W   + LAGY Q DAHE  +A L +LH H                       C  D +   + +      + C+CI+ Q F   L+S +        S  ++   D+SL++      F   S   E+S        G   + D L                C +C     +TKQ ++ +LP +   H KR         K+ T + FP ELD+ PF++S +           T+ +  E+KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L  +    + + PQ Y
Sbjct:   78 RGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRC-EMPSPELCLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRH-----------------------CKGDDVGKVASNP-----NHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSLNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMKKLPVVACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSKETRVNGQLQLPTNSANNENKYSLFAVVNHQGTLESGHYTSFIRHHRDQWFKCDDAVITKASIKDVLDSEGYLLFYHKQVLEPEPEKVKEMTPQAY 438          

Query:  479 RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI------FRNGSVSLEASFRS---YFGTERMKDAL----------------CSTCLKLG-ATKQYSLFQLPNIFSVHLKR----CHANSKVNTKVDFPEELDLAPFISSKQ-----------TDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSLVMKS-N*RTIIPQNY 1522
            RGL+N+GNTCF+N ++QALTHTP LRDF LSD HRC  +     CL CEM  + +E+Y     P+    LL+++W   + LAGY Q DAHE  +A L +LH H                       C  D +   + +      + C+CI+ Q F   L+S +        S  ++   D+SL++      F   S   E+S        G   + D L                C +C     +TKQ ++ +LP +   H KR         K+ T + FP ELD+ PF++S +           T+ +  E+KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L  +    + + PQ Y
Sbjct:   78 RGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRC-EMPSPELCLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRH-----------------------CKGDDVGKVASNP-----NHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSLNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMKKLPVVACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSKETRVNGQLQLPTNSANNENKYSLFAVVNHQGTLESGHYTSFIRHHRDQWFKCDDAVITKASIKDVLDSEGYLLFYHKQVLEPEPEKVKEMTPQAY 438          

Query:  479 RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI------FRNGSVSLEASFRS---YFGTERMKDAL----------------CSTCLKLG-ATKQYSLFQLPNIFSVHLKR----CHANSKVNTKVDFPEELDLAPFISSKQ-----------TDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSLVMKS-N*RTIIPQNY 1522
            RGL+N+GNTCF+N ++QALTHTP LRDF LSD HRC  +     CL CEM  + +E+Y     P+    LL+++W   + LAGY Q DAHE  +A L +LH H                       C  D +   + +      + C+CI+ Q F   L+S +        S  ++   D+SL++      F   S   E+S        G   + D L                C +C     +TKQ ++ +LP +   H KR         K+ T + FP ELD+ PF++S +           T+ +  E+KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L  +    + + PQ Y
Sbjct:   78 RGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRC-EMPSPELCLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRH-----------------------CKGDDVGKVASNP-----NHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSLNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMKKLPVVACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSKETRVNGQLQLPTNSANNENKYSLFAVVNHQGTLESGHYTSFIRHHRDQWFKCDDAVITKASIKDVLDSEGYLLFYHKQVLEPEPEKVKEMTPQAY 438          

Query:   20 ACSHLNIF-FENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI-----------------------FRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISS----------KQTDKSLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             CSH+N F  +N    L V  +    V+  S +  K KA S IC  C  H   L+    C HC+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  EQI KE +R  +    + +    W P  ++L LL++  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD H+C    QS +CL CEM ++ QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H                       C  D  NG   ++     + C+CI+ Q F   L+S +        S  ++ F D+SL++                         +G+ +L    R +   E +  +    CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S          +Q   SL  D KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L
Sbjct:    5 GCSHVNGFKVDNWKQNLRV--IYQCFVWSGSAETRKRKAKSCICHMCGAH---LNRLHSCLHCVFFGCFSKKHIHEHAKNKRHNLAIDLLYGGIYCFVCQDYIYDKDMEQIAKEEQRKAWKLQGIGEKYSMWEPTKRELELLRH-NPKRRKITANCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKCEM--QSNSCLVCEMSQLFQEFYSGHRSPHIPFRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRH-----------------------CKDD--NGKKANNP----NHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSDGSVVNGDSHPSGATTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKRLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPVDSLNNDNKYSLFAVVNHQGTLESGHYTTFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFL 503          

Query:   11 TNMACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI---------FRNGSVSLEASFRSYF-GTERMKDAL----------------CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISSKQ-----------TDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
            T   C+HL  F +    K  ++ +    V+  S +  K KA S +C  C  H   L+    C HC+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  E I KE +R  +    + +   +W P  ++L LLK+  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD HRC  ++   +CL CEM  + QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++            GS S   +  S+  GT  + D L                CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S +           TD    ++KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L
Sbjct:    8 TPPGCAHLGSF-KVDNWKQNLRAIYQCFVWSGSAEARKRKAKSCVCHVCGLH---LNRLHSCLHCVFFGCFTKKHIHEHAKSKRHNLAIELMYGGIYCFLCQDYIYDKDIEIIAKEEQRKAWKMQGVGEKFSTWEPTKRELELLKH-NPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRC-EMQSPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSESSVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIADVLDSEGYLLFYHKQFL 511          

Query:   20 ACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI-----------------------FRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISSKQTDK----------SLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             CSHL  F +    K  ++ +    V+  + +  K KA S +C  C  H   L+    C +C+F  C   KHI DH + K H + + L  G +YC  CQDY Y +  E I KE +R  +    + +   +W P  ++L LLK+  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD HRC  ++   +CL CEM  + QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++                         +G+ +L    R +   E +  +    CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S +  +          SL  D KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L
Sbjct:   22 GCSHLGSF-KVDNWKQNLRAIYQCFVWSGTAEARKRKAKSCVCHVCGIH---LNRLHSCLYCVFFGCFTKKHIHDHAKSKRHNLAIDLMYGGIYCFLCQDYIYDKDIEIIAKEEQRKAWKMQGVGEKFSTWEPTKRELELLKH-NPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRC-EMQSPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSEGSVVNGESHASGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPLDSLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFL 522          

Query:   20 ACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI-----------------------FRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISSKQ-----------TDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             CSHL  F +    K  ++ +    V+  + +  K KA S IC  C  H   L+    C +C+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  E I KE +R  +    + +   +W P  ++L LLK+  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD HRC  ++   +CL CEM  + QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++                         +G+ +L    R +   E +  +    CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S +           TD    ++KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L
Sbjct:   22 GCSHLGSF-KVDNWKQNLRAIYQCFVWSGTAEARKRKAKSCICHVCGVH---LNRLHSCLYCVFFGCFTKKHIHEHAKAKRHNLAIDLMYGGIYCFLCQDYIYDKDMEIIAKEEQRKAWKMQGVGEKFSTWEPTKRELELLKH-NPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRC-EMQSPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFL 522          

Query:   20 ACSHLNIF-FENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFA------------NFAMFDL-----SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI-----------------------FRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISS----------KQTDKSLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             CSH+N F  EN    L V  +    V+  + +  K KA S IC  C  H   L+    C +C+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  EQ+ KE +R  +              + M  +     +W P  ++L LL++  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD H+C  ++   +CL CEM  + QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++                         +G+ +L    R +   E +  +    CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S          +Q   SL  D KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L
Sbjct:    5 GCSHVNSFKVENWKQNLRV--IYQCFVWSGTPETRKRKAKSCICHMCGAH---LNRLHSCLYCVFFGCFTKKHIHEHAKNKRHNLAIDLLYGGIYCFMCQDYIYDKDMEQVAKEEQRKAWKLQVFSPALVSPYQYTMTGVGEKYSTWEPTKRELELLQH-NPKRRKITTNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKC-EMQSPNSCLVCEMSTLFQEFYSGHRSPHIPYRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSDAGVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPSDSLHNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFL 520          

Query:   17 MACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKASFICKKC------AYHKSCLSDS---MVCAHCIFSACRKNKHIEDHYRE-KGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDLSWRPEIKDLHLLKYVT---PLESSLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEI----------RSLDIQALADPSCSQD-----------------TING---------SSRSSS---TGVED-----------------DCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKD-ALCSTC-LKLGATKQYSLFQLPNIFSVHLKRCHANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSLVMKS 1492
            M+C+H + FF ++TN LA K +++ V FP +E+    KA+  C  C      + H S  S     + CAHC+   C  N+H++ H  E   H I V LE GE+YC  C+D+ YH  ++ +++  +R+Y A F + + SWRP  ++L L  ++T   P  ++L  +PTRGL+NMGNTCFLNVVIQALTHTP LRDFLL+DLHRC    +SR+CLACEMIR+TQEIY P   P+  SNLLY IW     LAGY Q DAHE  + +L+L+H HL       +E           R +    L+D S   D                  +NG         S R+SS   T V D                  CDCIVHQ F   LES I Y+   H+S  ++ F DLSL++ + GS SL+A   SYF  E +    LCS C +   A KQ+SL  LPN+   +LKRCH ++K+NT + FP +LDLAP++     D+S W+D+YSLY+V+NH GQ +SGHYT Y+R+    WCLCDDQ +  V +  VLQ+DAY+L YHKN L M+S
Sbjct:    1 MSCNHADSFFAHKTNALAYKTIVNRVTFPRTEKGLSKKANVHCLYCVQSNLSSTHNSIESRPTCLLACAHCVNFCCWGNRHVQAHRNEAPSHFIYVCLERGELYCAGCRDFVYHPVTDHLLESAQRMYLAQFGLSNQSWRPSFEELKLFPHITSIAPPCATLGGRPTRGLINMGNTCFLNVVIQALTHTPVLRDFLLADLHRCDNPARSRSCLACEMIRVTQEIYSPALTPFVPSNLLYAIWLHASHLAGYEQRDAHEFLITLLTLIHGHLVGEHAPFSETASEPCFPIKRRHIGSDRLSDDSNGSDDLKRLPVIPGHQPPPTPALNGTAVPSDAKRSPRASSESHTAVVDSASSQTSASSSRDSNGESCDCIVHQVFFGDLESVISYEGCGHSSSTVDPFLDLSLDVIQRGSTSLQACLTSYFRPESIDGLILCSQCNIGRPAVKQFSLLHLPNVLCFYLKRCHHDTKINTSITFPADLDLAPYLHQIVGDQSAWQDRYSLYAVLNHSGQTNSGHYTAYIRSGPGSWCLCDDQKIVAVSLEHVLQTDAYVLLYHKNLLAMRS 563          

Query:   17 MACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKASFICKKCAYHKSCLSDS--------MVCAHCIFSACRKNKHIEDHYREKG-HEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDLSWRPEIKDLHLLKY---VTPLESSLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHL---------SARENQVNEIRSLDIQALADPS-----------------------CSQDTINGSSRSSSTGVE-----------------------DDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKD-ALCSTC-LKLGATKQYSLFQLPNIFSVHLKRCHANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSLVMKS 1492
            M C H++ FF  +TN LA   +++ + FP SE+ F  KAS  C  CA   + L           + C HCI  +C   +H+E H +E+  H I + +E GE+YC  C D+ YH  +EQ  K   R+Y A+F +   +WRP   +L LL +   V PL + +  +PTRGLVNMGNTCFLNVVIQALTHTP LRD+LL+DLHRC    +SR+CLACEMIR+TQEIY PV  P+  SNLLY IW     LAGY Q DAHE  + +L+L+H HL         S  + +    R L    L++ S                       C +D    + R+++  V                        + CDCIVHQ F   LES I Y+   H+S  ++ F DLSL++ + GS SL+A   SYF  E +    LCS C +   A KQ+SL  LPN+   +LKRCH ++K+NT + FP +LDLAP++     D+S W D+YSLY+V+NH GQ +SGHYT Y+R+    WCLCDDQ +  V +  VLQ+DAY+L YHKN L M++
Sbjct:    6 MTCKHVDAFFMQKTNILAHNAIVNYLTFPRSEKGFAHKASIECADCAKAGTLLESEQALRPRCLLACTHCIHFSCWHPRHLEVHRKERPEHVIYICIERGELYCALCSDFVYHPVAEQSRKTAHRMYLAHFGLSSETWRPSFDELTLLPHISSVVPLSTKVGGRPTRGLVNMGNTCFLNVVIQALTHTPVLRDYLLADLHRCNNPARSRSCLACEMIRVTQEIYSPVVTPFVPSNLLYAIWLHASHLAGYEQRDAHEFLITLLTLIHGHLIGEHVPLGDSLHDQEPPSKRRLVASRLSEDSNTSSEFKPSMSRKHSDSSSHLSVCDKDLETLNERAATKHVHPTESSTSDSASSQASVSSSRDSGESCDCIVHQVFFGDLESVISYEGCGHSSSTVDPFLDLSLDVIQRGSTSLQACLTSYFRPESIDGLILCSQCNVGRPAVKQFSLLHLPNVLCFYLKRCHHDTKINTSITFPADLDLAPYLHQVDGDRSAWSDRYSLYAVLNHSGQTNSGHYTAYIRSGPGSWCLCDDQKIVSVSLEHVLQTDAYVLLYHKNLLAMRT 566          

Query:   17 MACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKASFICKKCAYHKSCLSDS---------MVCAHCIFSACRKNKHIEDHYREKG-HEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDLSWRPEIKDLHLLKY---VTPLESSLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHL---------SARENQVNEIRSLDIQALAD---------PSCSQDTINGSS--------------RSSSTGVE-----------------------DDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKD-ALCSTC-LKLGATKQYSLFQLPNIFSVHLKRCHANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSLVMKS 1492
            M C H++ FF  +TN LA   +++ + FP SE+ F  KAS  C  CA  ++ L +S         + C HCI  +C    H++ H +E+  H I + +E GE+YC  C D+ YH  +EQ  K   R+Y A+F +   +WRP   +L LL +   V PL + +  +PTRGLVNMGNTCFLNVVIQALTHTP LRD+LL+DLHRC    +SR+CLACEMIR+TQEIY PV  P+  SNLLY IW     LAGY Q DAHE  + +L+L+H HL         S  + +    R L    L++         PS S+    GSS              R+++  V                        + CDCIVHQ F   LES I Y+   H+S  ++ F DLSL++ + GS SL+A   SYF  E +    LCS C +   A KQ+SL  LPN+   +LKRCH ++K+NT + FP +LDLAP++     D+S W D+YSLY+V+NH GQ +SGHYT Y+R+    WCLCDDQ +  V +  VLQ+DAY+L YHKN L M++
Sbjct:    1 MTCKHVDAFFMQKTNILAHNAIVNYLTFPRSEKGFAHKASIECADCAKART-LPESEQALRPRCLLACTHCIHFSCWHPSHLDVHRKERPEHVIYICIERGELYCALCSDFVYHPVAEQSRKTAHRMYLAHFGLSSETWRPSFDELTLLPHISSVVPLSTKVGGRPTRGLVNMGNTCFLNVVIQALTHTPVLRDYLLADLHRCNNPARSRSCLACEMIRVTQEIYSPVVTPFVPSNLLYAIWLHASHLAGYEQRDAHEFLITLLTLIHGHLIGEHVPLGDSLHDQEPPSKRRLVASRLSEDSNIPSEFKPSMSRKHSGGSSHLSVCDKDLETLNERAATKHVHPTESSTSDSASSQASVSSSRDSGESCDCIVHQVFFGDLESVISYEGCGHSSSTVDPFLDLSLDVIQRGSTSLQACLTSYFRPESIDGLILCSQCNVGRPAVKQFSLLHLPNVLCFYLKRCHHDTKINTSITFPADLDLAPYLHQVDGDRSAWSDRYSLYAVLNHSGQTNSGHYTAYIRSGPGSWCLCDDQKIVSVSLEHVLQTDAYVLLYHKNLLAMRT 561          

Query:   17 MACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKASFICKKCAYHKSCLSDS--------MVCAHCIFSACRKNKHIEDHYREKG-HEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDLSWRPEIKDLHLLKY---VTPLESSLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHL---------SARENQVNEIRSLDIQALAD---------PSCSQDTINGSS--------------RSSSTGVE-----------------------DDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKD-ALCSTC-LKLGATKQYSLFQLPNIFSVHLKRCHANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSLVMKS 1492
            M C H++ FF  +TN LA   +++ + FP SE+ F  KAS  C  CA   +  +          + C HCI  +C   +H+E H +E+  H I + +E GE+YC  C D+ YH  +EQ  K   R+Y A+F +   +WRP   +L LL +   V PL + +  +PTRGLVNMGNTCFLNVVIQALTHTP LRD+LL+DLHRC    +SR+CLACEMIR+TQEIY PV  P+  SNLLY IW     LAGY Q DAHE  + +L+L+H HL         S  + +    R L    L++         PS S+   + SS              R+++  V                        + CDCIVHQ F   LES I Y+   H+S  ++ F DLSL++ + GS SL+A   SYF  E +    LCS C +   A KQ+SL  LPN+   +LKRCH ++K+NT + FP +LDLAP++     D+S W D+YSLY+V+NH GQ +SGHYT Y+R+    WCLCDDQ +  V +  VLQ+DAY+L YHKN L M++
Sbjct:    1 MTCKHVDAFFMQKTNILAHNAIVNYLTFPRSEKGFAHKASIECADCAKAGTLPASEQALRPRCLLACTHCIHFSCWHPRHLEVHRKERPEHVIYICVERGELYCALCSDFVYHPVAEQSRKTAHRMYLAHFGLSSETWRPSFDELTLLPHISSVVPLSTKVGGRPTRGLVNMGNTCFLNVVIQALTHTPVLRDYLLADLHRCNNPARSRSCLACEMIRVTQEIYSPVVTPFVPSNLLYAIWLHASHLAGYEQRDAHEFLITLLTLIHGHLIGEHVPLGESLHDQEPPSKRRLVASRLSEDSNNSSEYKPSMSRKHSDSSSHLSVCDKELETLNERAAAKHVHPTESSTSDSASSQASVSSSRDSGESCDCIVHQVFFGDLESVISYEGCGHSSSTVDPFLDLSLDVIQRGSTSLQACLTSYFRPESIDGLILCSQCNVGRPAVKQFSLLHLPNVLCFYLKRCHHDTKINTSITFPADLDLAPYLHQVDGDRSAWSDRYSLYAVLNHSGQTNSGHYTAYIRSGPGSWCLCDDQKIVSVSLEHVLQTDAYVLLYHKNLLAMRT 561          

Query:   17 MACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKASFICKKCA----YHKSCLSDS-----MVCAHCIFSACRKNKHIEDHYRE--KGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDLSWRPEIKDLHLLKYVT---PLESSLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHL---------SARENQVNEIRSL-----------------DIQALADPSCSQDTINGSSRS-------SSTGVE--------------------------DDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKD-ALCSTC-LKLGATKQYSLFQLPNIFSVHLKRCHANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSLVMKS 1492
            M C H + FF  +TN +A K +++ + FP SE+ F  KAS  C  C       K  +  S     + CAHCI  +C  NKH  DH+R+    H + V LE GE++C  C D+ YH  +EQ  +  +RLY   F +    WRP  ++L LL ++T   PL + L  +PTRGL+NMGNTCFLNVVIQALTHTP LRD+LL+DLHRC    +SRNCLACEMIR+TQEIY P   P+  SNLLY IW     LAGY Q DAHE  + +L+L+H HL          A +  V   R L                  +++      S+  +NG++ S       ++TGV+                          + CDCIVHQ F   LES I Y+   H+S  ++ F DLSL++ + GS SL+A   SYF  E +    LCS C +   A KQ+SL  LPN+   +LKRCH ++K+NT + FP +LDLAP++S     +S W+D+YSLY+V+NH GQ +SGHYT Y+R+    WCLCDDQ +  V +  VL++DAY+L YHKN L +++
Sbjct:    1 MTCKHADNFFIQKTNVIAYKTIVNYMTFPRSEKSFAHKASIACTFCTNSAESEKPKIDRSRPYCLLACAHCIHFSCW-NKHHIDHHRQDHPEHVLYVCLERGELFCTACADFVYHPIAEQAHRVAQRLYLTQFGLCSQHWRPSFEELKLLPHITSVIPLSTKLGNRPTRGLINMGNTCFLNVVIQALTHTPVLRDYLLADLHRCNNPVRSRNCLACEMIRVTQEIYSPALTPFVPSNLLYAIWLHASHLAGYEQQDAHEFLITLLTLIHGHLVGEHIPLGDPAPDTGVPPKRRLTVSDRLSDNSASSSDSKPVESRKPMGHSRIPVNGANLSDEPGTHPATTGVKRPCPSESHPSDSASSQTSVSSSRDSGESCDCIVHQVFFGDLESVISYEVCGHSSSTVDPFLDLSLDVIQRGSTSLQACLTSYFRPESIDGLILCSQCNVGRPAVKQFSLLHLPNVLCFYLKRCHHDTKINTSITFPADLDLAPYLSHVDGGQSAWQDRYSLYAVVNHSGQTNSGHYTAYIRSAPGSWCLCDDQKIVSVSLEHVLRTDAYVLLYHKNLLAIRA 566          

Query:   20 ACSHLNIF-FENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI----------------------FRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISSKQ-----------TDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             CSH+N F  +N    L V  +    V+  S +  K KA S +C  C  H   L+    C HC+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  EQI KE +R  +    + +   +W P  ++L LL++  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD H+C    Q+ +CL CEM ++ QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++                         G+ +L    R +   E +  +    CS C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S +            D    ++KY+L++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L
Sbjct:    5 GCSHVNGFKVDNWKQNLRV--IYQCFVWSGSAETRKRKAKSCMCHMCGAH---LNRLHSCLHCVFFGCFTKKHIHEHAKTKRHNLAIDLLYGGIYCFVCQDYIYDKDMEQIAKEEQRKAWKLQGIGEKYSTWEPTKRELELLRH-NPKRRKITANCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKCEM--QANSCLVCEMSQLFQEFYSGHRSPHIPFRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSDGNVNGESHPTGATTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKRLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPVDTLNNDNKYALFAVVNHQGTLESGHYTTFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFL 503          

Query:  191 CAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDL--SWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI-----------------------FRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISSKQTDKSLWE-----------DKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
            C +C+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  EQI KE +R  +    + +   +W P  ++L LL++  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD H+C    QS +CL CEM ++ QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H    +N                                   + C+CI+ Q F   L+S +        S  ++ F D+SL++                          GS +L    R +   E +  +    C  C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S +  +   +           +KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK  L
Sbjct:   12 CLYCVFFGCFSKKHIHEHAKNKRHNLAIDLLYGGIYCFACQDYIYDKDLEQIAKEEQRKAWKLQGVGEKFSTWEPTKRELELLRH-NPKRRKITTNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKCEM--QSNSCLVCEMSQLFQEFYSGHRSPHIPFRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDN----------------------------GKKGNNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGGDSGLVNGEGHLTGSTTLTDCLRRFTRPEHLGSSAKIKCGGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRVNGQYQQSVDLLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFL 457          

Query:  443 TPLESSLDCKPTRGLV---NMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLAC--EMIRITQEIY-KPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIV-YDCGVHTSRHLEIFRDLSLEIFRN--GSVSLEASFRSYFGTERMKDALCSTCLKLGA----TKQYSLFQLPNIFSVHLKRCHA----NSKVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEA-NIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
            +P+  SL+ K  +GLV   N+GNTCF+N ++Q L++T +LRD+ L + HR      SR   A   E  R+ Q ++    S   + S     I        GYNQ DA E    +L  LH       N+VN +         D     D   G    S     +D   +    F+  L+S +   +CG + S   + F DLSL I +   G VSL    R +   + +      TC +  A    TK++++ + P I  +HLKR       +SK++T V+FP ++LDL  F S + +        Y+LY+V NH G    GHYT Y    A   W   +D  V  +  ++V  SDAY+LFY +  L
Sbjct:  219 SPVRDSLNSKSAQGLVGLKNLGNTCFMNSILQCLSNTHSLRDYCLHNSHRRDLNNNSRTNTALMEEFARLIQAMWMSSGSEAVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLH-------NEVNRVTVRPRATTEDFDHLPDEEKGKKMWSKYLEREDSKIV--DLFVGQLKSSLTCTECG-YCSTVFDPFWDLSLPIAKKGYGEVSLMDCVRLFTKEDVLDGDEKPTCYRCKARRRCTKKFTIQRFPKILVLHLKRFSEARVRSSKLSTFVNFPMKDLDLREFASDRSSSAV-----YNLYAVSNHSGTTMGGHYTAYCCNPATGEWYTYNDSRVTPMSSSQVRSSDAYVLFYERAGL 568          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLAC--EMIRITQEIY-KPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIV-YDCGVHTSRHLEIFRDLSLEIFRN-GSVSLEASFRSYFGTERMKDALCSTCLKLGA----TKQYSLFQLPNIFSVHLKRCHA----NSKVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANI-WCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
            GL N+GNTCF+N ++Q L++T +LRD+ L + HR      SR   A   E  R+ Q ++    S   + S     I        GYNQ DA E    +L  LH       N+VN +         D     D   G    S     +D   +    F+  L+S +   +CG + S   + F DLSL I +  G VSL    R +   + +      TC +  A    TK++++ + P I  +HLKR       +SK++T V+FP ++LDL  F S + +        Y+LY+V NH G    GHYT Y    A   W   +D  V  +  ++V  SDAY+LFY +  L
Sbjct:   63 GLKNLGNTCFMNSILQCLSNTHSLRDYCLHNSHRRDLNNNSRTNTALMEEFARLIQAMWMSSGSEAVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLH-------NEVNRVTVRPRATTEDFDHLPDEEKGKKMWSKYLEREDSKIV--DLFVGQLKSSLTCTECG-YCSTVFDPFWDLSLPIAKGYGEVSLMDCVRLFTKEDVLDGDEKPTCYRCKARRRCTKKFTIQRFPKILVLHLKRFSEARVRSSKLSTFVNFPMKDLDLREFASDRSSSAV-----YNLYAVSNHSGTTMGGHYTAYCCNPATGEWYTYNDSRVTPMSSSQVRSSDAYVLFYERAGL 395          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLAC-----EMIRITQEIYKPVS-VPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIV-YDCGVHTSRHLEIFRDLSLEIFR-NGSVSLEASFRSYFGTERMKDALCSTCLKLGA----TKQYSLFQLPNIFSVHLKRCH----ANSKVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANI-WCLCDDQNVHHVPITEVLQSDAYMLFYH 1468
            GL N+GNTCF+N ++Q L++T  LRD+ L + HR      + NC A      E  ++TQ ++   S    + S+    I        GYNQ DA E    +L  LHN ++ R +    +   D   L+D   ++   N       + V D         F+  L+S +   +CG   S   + F DLSL I + +G V+L    R +   + +      TC +  A    TK++S+ + P +  +HLKR        +K++T V+FP +ELDL  F S    D S+    Y+LY+V NH G    GHYT Y R  +   W   +D  V  +  ++V  SDAY+LFY 
Sbjct:   63 GLRNLGNTCFMNSILQCLSNTHDLRDYCLRNTHR---TDLNNNCRANAALMEEFAKLTQILWTSASNEAISPSDFKTQIQKYAPRFVGYNQQDAQEFLRFLLDGLHNEVN-RVSVRPRVPVEDFDHLSDDEKAKRMWNKYLEREDSKVVD--------LFVGQLKSSLTCSECGF-CSTVFDPFWDLSLPIAKSSGEVALIDCLRLFTKEDVLDGNEKPTCQRCKARRKCTKKFSIQKFPKVLVLHLKRFSEARVKTAKLSTFVNFPIKELDLREFAS----DNSM-NAIYNLYAVSNHTGTTLGGHYTAYCRNPSTGEWYTYNDSRVSPMSSSQVRSSDAYVLFYE 391          

Query:  134 SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYF--ANFAMFDLSWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSL-LHNHLSARENQVNEIRSLDIQALADP--SCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLE-------------------------IFRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKR----CHANSKVNTKVDFPEELDLAPFISSK---------QTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
            S +C  C  H   L     C HCI+  C   +HI +H + K H + + L  G ++C  CQDY Y    E + +E +R  +    F    + W P  ++L LLK   P    +    T   RGLVN+GNTCF+N ++QALTHTP LRDF LSD HRC  +     CL CEM R+ QE+  P         L+ +   Q + +  ++           LS+ LH+                   +  P  SC  D  NG  RS++    + C+CI+ Q F   L+S +        S  ++ F D+SL+                         +   G  +L    R +   E +  +    C+ C     +TKQ ++ +LP +   HLKR         K++T V FP ELD+ PF++S          QT +S  E+KYSL++V+NH+G   SGHYT ++R   + W  CDD  + H  +T+VL S+ Y+LFYHK  L
Sbjct:   15 SCVCHLCGAHFGRLH---ACLHCIYFGCFARRHIHEHAKAKRHPLSMDLYHGTVFCLLCQDYVYDRDLELVSREEQRRAWRLQGFGDRYIGWEPSRRELELLKQ-NPKRRKISANCTVGLRGLVNLGNTCFMNCIVQALTHTPLLRDFFLSDRHRC-GMPSPEACLVCEMCRLFQEVGNPARCLAPPFCLVPIARCQCRKIMEFD-----------LSMTLHS------------------GVCWPFFSCIGDA-NG-KRSNN---PNHCNCIIDQIFTGGLQSDVTCQVCQGVSTTIDPFWDISLDLPGSSSPFWPLSPTAESGIPNGGGPLIPAGPTTLNDCLRRFTRPEHLGSSAKIKCNGCHSYQESTKQLTMRKLPIVACFHLKRFEHSARLRRKISTYVSFPLELDMTPFMNSSKDSRVNGQYQTGESTNENKYSLFAVVNHQGTLESGHYTSFIRLHRDQWFKCDDAVITHASVTDVLDSEGYLLFYHKQIL 474          

Query:  917 CDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRN---------------------------GSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKR----CHANSKVNTKVDFPEELDLAPFISSKQ-----------TDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
            C+CI+ Q F   L+S +        S  ++ F D+SL++  +                           G  SL    R +   E +  +    CS C     +TKQ ++ +LP +   HLKR         K+ T V FP ELD+ PF++S +            D    E+KYSL++V+NH+G   SGHYT ++R   + W  CDD  + H    +VL S+ Y+LFYHK  L
Sbjct:   29 CNCIIDQIFTGGLQSDVTCQVCQGVSTTIDPFWDISLDLPGSSTPFWPLSPGSEGSLLLANGGEGHAAAGPTSLTDCLRRFTRPEYLGSSAKIKCSGCRSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRKKITTYVSFPLELDMTPFMASSKESRVNGQHQVGGDALSSENKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITHAGARDVLDSEGYLLFYHKQFL 262          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLAC------EMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLD--IQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSV--SLEASFRSYFGTERMKDA---LCSTC-LKLGATKQYSLFQLPNIFSVHLKR----CHANSKVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYV-RTEANIWCLCDDQNVHHVPITEVLQSDAYMLFY 1465
            GL N+GNTC++N V+Q L++T +L ++ L+  +    +    N L        E   I + ++          +  ++I        G  QHD+ EL + +L  LH  L    NQ   +R  +   + L+D   +Q   +     +    E     + H  F +T++      C    SR  E+F +L+L +  + +   +L+   + +   E+M DA   LCS C  +  + K   +++LP +  +HLKR         K+ T V FP   LD+ P+I +K    S    +Y+LY+V NH G    GHYT Y   T  + W   DD  V  +    V  S  Y+LFY
Sbjct:   97 GLRNLGNTCYMNSVVQCLSNTTSLAEYFLTSQY-VNNINSRNNPLGRKGQVVEEFAVIVRALWSGQYRSITPRDFKFMIGRLNDQFCGTEQHDSQELLIFLLDGLHEDL----NQAKRVRVKEEKTEHLSDSMAAQLAWDAYKHIN----ESILVTLFHGQFRSTIK---CLTC-QKVSRTFEVFMNLTLHLPSDTTSKCTLQDCLQMFSKPEKMTDANRYLCSHCKQRRESVKTMEIWKLPPVLIIHLKRFSYSGRWKQKLQTNVGFPLTSLDMKPYIINKDNRYS----EYNLYAVSNHYGSLDGGHYTAYTHNTVRDSWFKFDDHEVEFIYPKNVSTSAGYILFY 427          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQS-RNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKI-VYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKDALCST--------CLKLGATKQYSLFQLPNIFSVHLKR------CHANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSS-GHYTVYVRTEANIWCLCDDQNVHHVPITEV-----LQSD-------AYMLFYH 1468
            GLVN GNTC+ N V+QAL      R+ +L D    P  K++   CLA     I  +  K   +P      +  +  + +    Y Q DAHE    +L+ + + L   + Q  E ++  ++     + +    + S+++  T         VH  F  TL ++    +C   +S+  E F DLS+++ +N S++   S R +  TE     LCS         C K  A K+  + +LP I ++HLKR       H  +K++ +V FP EL L  F +S   D +  +  Y L +V+ H G   + GHY   V++    W L DD  V  +    +     L +D        Y+LFY 
Sbjct:   36 GLVNFGNTCYCNSVLQALYFCKPFREKVL-DYKVQPKKKENLLTCLADLFHSIATQKKKVGVIP--PKKFISRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEEKKQ--ERQNGKLKNGVAAAAAAADGDDSTKTEPT--------WVHDIFQGTLTNETRCLNCETVSSKD-EDFLDLSVDVEQNTSITHCLSPRGFSNTE----TLCSEYKYYCEQCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FNTS--GDATNPDRMYDLVAVVVHCGSGPNRGHYITIVKSHG-FWLLFDDDIVEKIDPQAIEEFYGLTTDVSKNSESGYILFYQ 370          

Query:  926 IVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLE-----------IFRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLGATKQYSLFQLPNIFSVHLKRCHANS-----KVNTKVDFPEELDLAPFISSKQTDKSLW----EDKYSLYSVINHRGQN-SSGHYTVYV-RTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHK 1471
            +V   F   L S++      HTSR  E+F DLSL+           +  NG  +L      +  TE +       C TC +  A KQ  + +LP +  +HLKR   +      K+   V F + L + P+ S      S         Y L +V+ H G+   SGHYT Y    E   W  C+D  +  V + EV ++ AY+LFY +
Sbjct:    9 VVASIFQGELLSQVTCLSCAHTSRRNELFWDLSLDFPERYHGLAKAVDTNGGCTLTEMLAKFTETEALDGGKVYSCDTCNE--AQKQLLVHRLPRVLRLHLKRFRWSGRNHREKIGVHVAFEQRLCMTPYCSRDGGSGSGSGGADPSTYDLSAVVMHHGRGFGSGHYTAYCYNAEGGFWVHCNDSRLDVVSVAEVCRAQAYILFYTR 213          

Query:   23 CSHLNIFFENQTNKLAVKRLISAVVFPL--SEQEFKLKASFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDLSWRPEIKDLHLLKYVTPLESSLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLH--RCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSN------------LLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIV-YDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKD--ALCSTCLKL-GATKQYSLFQLPNIFSVHLKRCH-----ANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDK-----YSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFY 1465
            C H+   F+N+ +K  V +  +A  + L  S  + K   +  C  C  H+     + +C  C F  C  + H   H ++ GH   ++   G ++C +C+DY               +   N A+    W     D    K + P     D     GL+NMG+TCF++ ++Q L H P      +S +H   C  V+    C +C + +I  E+Y  ++   A S+            LL   W   Q+LAGY+Q DAHE +  I+           NQ+++   LD+               +++  S      C+CIVH  F  +LES IV   C  ++   ++ F DLSL+I       L     S+   E++KD    C  C     A KQ  + +LP++  + LKR       +N K++  ++FP  L++  + S+K+ DK     K     Y L  +++H+G  + GHY  + +     W   +D  V  +   EVL+  AY+LFY
Sbjct:    4 CPHIQQVFQNEKSKDGVLKTCNAARYILNHSVPKEKFLNTMKCGTC--HEINSGATFMCLQCGFCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDY------------IGNIDLINDAILAKYW-----DDVCTKTMVPSMERRD--GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCK-VRSPDKCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFII-----------NQIHQSYVLDLP--------------NAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDI--KDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFY 465          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLA----------------GYNQHDAHELFLAILSLLHNHLSAR--ENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI--FRNGSVSLEASFRSYFGTERM--KDALCSTCLKLGATKQYSLFQ-LPNIFSVHLKRCHAN------SKVNTKVDFPEELDLAPFISS---KQTDKSLWEDK----YSLYSVINHRGQNSSGHYTVYVRTEA-NIWCLCDDQNVHHVPITEVLQSD 1447
            G  N G TC+LN ++Q+   T   R  +    +  PT  +S N                 SVP AL    Y +  QV D+                  + QHD  EL   ++  L N++     E ++NEI                                        F+  ++S I      + S  +E F DL L +  F+N    L+ SF +Y   E M  ++   +    L   ++  +F+  P +  + LKR   +       KVN K +FPE +DL+PF+     K+T  S  +DK    Y+L+ V+ H G  S+GHY   ++    + W   DD+ V  V   +V Q +
Sbjct:  206 GFRNQGATCYLNSLLQSYFFTKYFRKLV----YEIPTEHESPNN----------------SVPLALQRAFYQL--QVSDIPLDTLELTRSFGWDTAESFTQHDVQELNRILMDRLENNMKGTPVEGKLNEI----------------------------------------FVGKMKSYIKCINVDYESARVEDFWDLQLNVKNFKN----LQESFDNYIEMELMNGENQYAAQDYGLQDAQKGVIFESFPPVLHLQLKRFEYDFNYDQMVKVNDKYEFPETIDLSPFVDKDVLKKTLDSENKDKNPYVYNLHGVLVHSGDISTGHYYTLIKPGVEDQWYRFDDERVWRVTKKQVFQEN 498          

Query:  440 VTPLES-SLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLH----RCPTVKQSRNCLACEMIRITQEIYKP---VSVPYALSNLLYVIW-SQVQDL-AGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIV----------YDCGV--HTSRHLEIFRDLSLEIFRNGS---VSLEASFRSYFGTERM---KDALCSTCLKL-GATKQYSLFQLPNIFSVHLKRC-HANSKVNTKVDFPEELDLAPFISSK--------------QTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTE-ANIWCLCDDQNVHHVPI---TEVLQSDAYMLFYHK 1471
            VTP  S + D     GL N+GN+C++N +IQ +  T  L    L D +       +   S+  LA    R+   +YK     S   ++S + + +    V  L    +Q D  E    +L  LH  L+              Q  ++P   + +    +R     +      I  + F+ T  S IV            C V  HTS   + F  LS+ I +  S   +++E  FR +   E +   +  LC  C K   +TKQ ++ +LP    VHLKR  +  +K N  V +P  LDL PF ++                    +   KY LY V  H G    GHYT YV+      W   DD    + P+    + + S+AY+LFYH+
Sbjct:  548 VTPTSSHNYDLDFAVGLENLGNSCYMNCIIQCILGTHELTQIFLDDSYAKHININSKLGSKGILAKYFARLVHMMYKEQVDGSKKISISPIKFKLACGSVNSLFKTASQQDCQEFCQFLLDGLHEDLN--------------QCGSNPPLKELSQEAEARREKLSLR-IASSIEWERFLTTDFSVIVDLFQGQYASRLKCKVCSHTSTTYQPFTVLSIPIPKKNSRNNITIEDCFREFTKCENLEVDEQWLCPHCEKRQPSTKQLTITRLPRNLIVHLKRFDNLLNKNNDFVIYPFLLDLTPFWANDFDGVFPPGVNDDELPIRGQIPPFKYELYGVACHFGTLYGGHYTAYVKKGLKKGWLYFDD--TKYKPVKNKADAINSNAYVLFYHR 922          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLH----RCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGY--------NQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVE----DDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERM---KDALCSTCLK-LGATKQYSLFQLPNIFSVHLKRC-HANSKVNTKVDFPEELDLAPFISSKQTDKSLWED-----------KYSLYSVINHRGQNSSGHYTVYV-RTEANIWCLCDDQNVHHVPI-TEVLQSDAYMLFYHK 1471
            GL N+GN C++N ++Q L  T  L    L + +       + + S+  LA     +   +++  +        + V   Q + + G+         Q D  E    +L  LH  L    NQ    + L  + L+D            ++S+   E     D   I+   F     S++      HTS   + F  LS+ + R  + ++   FR +   ER+   +   C  CLK   +TKQ  + +LP    ++LKR  +  +K N  V +P  LDL P+ +     +++  +           +Y LY V  H G    GHYT YV +     W   DD     +   TE +   AY+LFY +
Sbjct:  447 GLENIGNCCYMNCILQCLVGTHDLVRMFLDNTYLNFINFDSSRGSKGLLAKNFAILVNNMHRHGAFTPPNVRTIPVQTIQFKKICGHINPMYSDSMQQDCQEFCQFLLDGLHEDL----NQNGSKKHL--KQLSDEEERMREKMSIRKASALEWERFLLTDFSAII-DLFQGQYASRLQCQVCEHTSTTYQTFSVLSVPVPRVKTCNILDCFREFTKCERLGVDEQWSCPKCLKKQPSTKQLKITRLPKKLIINLKRFDNQMNKNNVFVQYPYSLDLTPYWARDFNHEAIVNEDIPTRGQVPPFRYRLYGVACHSGSLYGGHYTSYVYKGPKKGWYFFDDSLYRPITFSTEFITPSAYVLFYER 803          

Query: 1109 CSTCLK-LGATKQYSLFQLPNIFSVHLKRCHA----NSKVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEA-NIWCLCDDQNVHHVPITEVLQSDAYMLFY 1465
            C TC +   ATKQ  L+  P+I  +HLKR  +    + K++  V+FP  +LDL+ ++  K   + L    Y LY+V NH G    GHYT YV+  A N W   DD  V        +   AY+LFY
Sbjct:  985 CPTCKEHRQATKQIQLWNTPDILLIHLKRFESQRSFSDKIDATVNFPITDLDLSRYVVYKDDPRGLI---YDLYAVDNHYGGLGGGHYTAYVKNFADNKWYYFDDSRVTETAPENSIAGSAYLLFY 1107          

Query:  476 TRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQS----RNCLACEMIRITQEIYK------PVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLS 793
            T GLVN+GNTC++N  +Q L H P LRD+ L D +     +++       +A     + Q++++        +  +  S     I       +GY Q D+ E    +L  LH  L+
Sbjct:  363 TTGLVNLGNTCYMNSALQCLVHIPQLRDYFLYDGYEDEINEENPLGYHGYVARAFSDLVQKLFQNRMSIMQRNAAFPPSMFKSTIGHFNSMFSGYMQQDSQEFLAFLLDSLHEDLN 478          

Query:   17 MACSHLNIFFENQTNKLAVKRLISAVVFPLSEQE-FKLKASF-ICKKCAYHKSCLSDSMVCAHCIFSAC-RKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIK-EFRRLY--FANFAMFDLSWRPEIKDLHLLKYVTPLESSLDCKPT-------RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFR----SYFGTERMKDALCSTCLKLG-ATKQYSLFQLPNIFSVHLKR---CHANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHK 1471
            ++C HLN F   + N L   R I       S +E  K KAS   C  C  + SC   S  C  C++  C   ++HI+ H R  GH + + L  G +YC  C DY+Y +  + I + ++RR +    N     L W P   ++ L      LE+    K T       RGL+N+GNTCF+N ++QALTHTP LRD+ LSD H C     +  CL CEM  + QE Y    VP++   LL+++W+  + LAGY Q DAHE F+A L +LHN+                       C +D  +  +   +    + C+CI+ + F   L+S ++       S  ++ F D+SL++  +G   L    R       G+E      C+ C     +TKQ S+ +LP +   HLKR      + K++T + FP+ELD+APF+SS          KYSL++V+NH G    GHYT ++R + N W  CDD  +    I +VLQS+ Y+LFYH+
Sbjct:    2 VSCIHLNRF--KKANGLKTYRKIHTHFISCSSREALKRKASSCFCHGCGTY-SCRLHS--CLSCVYFGCYTGSRHIQQHARTTGHSLAIDLNHGTVYCFICGDYKYDKDFDNINRDQYRRAWRKLGNGCAKFLPWEPTKSEVKLF-----LENPKKVKITKNSTIGLRGLINLGNTCFMNCIVQALTHTPLLRDYFLSDQHNCKG--DAGTCLVCEMGLLFQEFYSGQKVPHSPFKLLHLVWTHARHLAGYEQQDAHEFFIAALDVLHNY-----------------------CKEDAPDKLAVKPNN--HNQCNCIIDRIFTGGLQSDVICQTCNCVSTTVDPFWDISLDL-GHGDHKLVIFCRFTRPESLGSE--SKIKCNKCQSYQESTKQLSMRKLPIVVCFHLKRFEHSKKSKKISTYIPFPQELDMAPFLSS----------KYSLFAVVNHSGTLEVGHYTAFIRQQNN-WFKCDDAWITKATIDDVLQSEGYLLFYHR 456          

Query:  482 GLVNMGNTCFLNVVIQALTHT----------PALRDFLLSDLHRCPTVKQSR----NCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSC-SQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI-----------FRNGSVSLEASFRSYFGTERMKDALCSTCLKLG----ATKQYSLFQLPNIFSVHLKR----CHANSKVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQN-SSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHK 1471
            GL N+GNTCF+N V+Q+L++           PA      +   + P   +SR     CL  E+ ++   +++   V ++   L   +W  V    GY Q DAHE    ++  LH  L                 L+  +C  QDTI        TG+           F   L+S++     +  SR L+ F DLSLEI             N    LE   + +   E++ ++    CLK      +TK++ + +LPN+  +HLKR        SK++T V FP   LD++P+    Q         Y L +V+ H G   S+GHYT +   +   W   +D +V  +    V +   Y+ FY +
Sbjct:  109 GLRNLGNTCFMNAVLQSLSNIQTFSCYFKDLPAFELRTDTSCEKNPYFTRSRKSDDGCLVEELRKVLCALWQGNCVSHSPEALFSTVWKVVPRFRGYQQQDAHEFMHYLMDRLHTEL----------------LLSQKACFGQDTI-------VTGI-----------FGGILQSEVTCLTCMTESRKLDPFLDLSLEIPPEFQTRKAKSRENPFCQLEDCMKHFVALEKLAESELYMCLKCKKKEQSTKKFWIQRLPNVLCLHLKRFRFQAFLRSKIDTYVQFPIRGLDMSPYTLKGQEKGETKPVLYDLAAVVVHHGSGVSAGHYTTFAFHDG-AWYNFNDSSVSRIDEEMVAKCKGYIFFYTR 439          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQS--RNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLA----GYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIV-YDCGVHTSRHLEIFRDLSLEIFR-------------NGSVSLEASFRSYFGTERMKDALCSTC----LKLGATKQYSLFQLPNIFSVHLKRCHA---NSKVNTKVDFP--EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVR-TEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHK 1471
            GL N+GNTCF+N ++Q L+ T  L + +L   +      +S  +  L      + + ++K  +   A+S   +   +Q+Q  A    G+NQ DA E    +L  LH+ L       N+++      + +   S   +  + ++    +E D + ++   F+  L+S ++  +CG   S   + F DLSL I R              G V +      +   E +      TC     K  +TK++++ + P I  +HLKR       SK+ T V FP     +L  F +     +S     YSLY+V NH G    GHYT Y +  ++  W   +D  V  +  + V    AY+LF+ K
Sbjct:    7 GLRNLGNTCFMNSILQCLSSTWLLTNIVLKGTYVSSINNKSSMKGRLVQAFADLIKSMWKHDATESAIS--AHAFKTQIQRFAPRFVGFNQQDAQEFLHFLLEGLHDDL-------NKVQEKPKYKMCEFDNSLSDLEKAKKAWKLYIERD-NSLITDLFVGVLKSTLICLECGFK-SVTFDPFWDLSLPIPRKSGSRYSSSRYTDGGDVDIRDCMELFTKEEVLDGDERPTCEKCKKKRKSTKKFTVQRFPRILVIHLKRFSGYGFRSKLQTNVVFPVTSPQELGEFAADPSEGQSA---VYSLYAVSNHSGSTYGGHYTAYCKHPQSRQWHCFNDSRVDQISSSRVTGPQAYILFFEK 352          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLH--RCPTVKQSRNCLACEMIR--------ITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCD------CIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKDAL--CSTCLK-LGATKQYSLFQLPNIFSVHLKRCHA----NSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQN-SSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHK 1471
            GL N+GNTCFLN V+Q LT+T  L ++L +  H   C  V     C+ CE+ R           E  KP+ +   L ++        + L   +Q DAHE    +                                   I+G  +S   G  +  D       IVH  F     S++      +TS   +   ++ ++I  + SV + A  R         D L  C  C K + A KQ  + + PNI ++ LKR         KV+ ++ + E LDL PF+++ +        KY LY V+ H G + +SGHY  YVR   + W   +D  V  V +  VL   AY+LFY +
Sbjct:   92 GLSNLGNTCFLNSVVQVLTYTAPLVNYLATQEHTRECQMVG---FCMMCELQRHILRTFNHQQNESIKPLCIIQRLRSI-------AKHLRFGHQEDAHEFLRYV-----------------------------------IDGMQKSCLAGQPEKMDRYSKETTIVHGIFGGYYRSQVQCLKCHNTSNTFDPLMEIMVDIKHSPSV-VRAIQRMCKAELLDGDNLYQCPRCKKKVPAHKQVLIHRPPNILTIQLKRFDYHHMFGGKVSKEITYTEHLDLRPFMTNPKGPPL----KYKLYGVLVHSGYSCNSGHYYCYVRGSNDCWYNMNDSMVRQVGLNTVLAQQAYLLFYSR 395          

Query:  491 NMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQ--VQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSST--GVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGS-VSLEASFRSYFGTERMKD---ALCSTCLK-LGATKQYSLFQLPNIFSVHLKRCHANS----KVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEAN-IWCLCDDQNVHHVPITEVLQSDAYMLFY 1465
            N+GNTC++N V+Q L +T  L  + +S   R    K+  N L    + +  + Y   S+ ++     Y+  S        G  Q D  E    ++  LH         V +IR        D     D I+ +  ++ T        + ++   F    +S +        S   E F +L+L +  N +  SL    + +   ERM       C  C +   A+KQ  +++LP I  VHLKR   +     K+ T V FP + LD++ +I+      +     Y LY V NH G    GHYT + +   N  W   DDQ V  +   +++ S AY+LFY
Sbjct:   84 NLGNTCYMNSVLQCLFNTAPLAAYFVSGAFRDDINKE--NPLGTSGMYL--DFYFITSINFSF----YLTSSPEFFTTFEGVCQQDFQEFLALMMDKLHE-------DVCQIRHKPYLKAPD-----DNIDPAEAANITWDNHRKRNESLMLNLFDGMFKSTVRCLVCAKDSVTYETFSNLTLPLPGNSNHCSLRDCIKLFTRAERMSGDDMWYCPRCKQHRVASKQLQIWRLPPILIVHLKRFQYDGMWRQKLQTAVSFPVDGLDMSGYITGPTKRPA-----YHLYGVSNHYGTMHGGHYTAFCKNAHNQRWFKFDDQVVTEMSANDIVSSAAYLLFY 398          

Query:   20 ACSHLNIF-FENQTNKLAVKRLISAVVFPLSEQEFKLKA-SFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFD--LSWRPEIKDLHLLKYVTPLESSLDCKPT---RGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEI-----------------------FRNGSVSLEASFRSYFGTERMKDAL---CSTCLKLG-ATKQYSLFQLPNIFSVHLKRCHANSK----VNTKVDFPEELDLAPFISS----------KQTDKSLWED-KYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
             CSH+N +  +N    L V  +    V+  + +  + KA S IC  C  H   L+    C +C+F  C   KHI +H + K H + + L  G +YC  CQDY Y +  EQI KE +R  +    + +   +W P  ++L LL++  P    +    T   RGL+N+GNTCF+N ++QALTHTP LRDF LSD H+C    QS +CL CEM ++ QE Y     P+    LL+++W+  + LAGY Q DAHE  +A L +LH H                       C  DTIN + + ++    + C+CI+ Q F   L+S +        S  ++ F D+SL++                         +GS +L    R +   E +  +    C  C     +TKQ ++ +LP +   HLKR   ++K    + T V FP ELD+ PF++S          +QT + L  D KYSL++V+NH+G   SGHYT ++R   + W  CDD  +    I +VL S+ Y+LFYHK+ L
Sbjct:    5 GCSHVNGYKVDNWKQNLRV--IYQCFVWSGTAETRRRKAKSCICHMCGAH---LNRLHSCLYCVFFGCFTKKHIHEHAKNKRHNLAIDLLYGGIYCFVCQDYIYDKEMEQIAKEEQRKAWKLQGIGEKYTTWEPTKRELELLRH-NPKRRKITTNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKCEM--QSNSCLVCEMSQLFQEFYSGHRSPHIPFRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRH-----------------------CKGDTINDNGKKANN--PNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGGDSGTVNGEGHLSGSTTLTDCLRRFTRPEHLGSSAKIKCGGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQTVEVLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKHFL 507          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSV-PYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIF--RNGSVSLEASFRSYFGTERMKDALCSTCLKLGA----TKQYSLFQLPNIFSVHLKRC----HANSKVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEA-NIWCLCDDQNVHHVPITEVLQSDAYMLFYH 1468
            GL N+GNTCF+N ++Q L++T  LRD+ L ++HR     ++   L  E  ++TQ ++  V++   + S+    I        G NQ DA E   ++L  LH       N+VN +      ++ D     D    S R  +  +  + D  V   F+  L+S +        S   + F DLS+ I   R G V+L+   R +   + +      TC K  A    TK++S+ + P I  +HLKR       +SK++T V+FP +ELDL  F S+  ++  +    Y+LY+V NH G    GHYT Y R  A   W   +D  V  +   +V  S+AY+LFY 
Sbjct:   60 GLRNLGNTCFMNSILQCLSNTSELRDYCLRNVHRLDVNNRTNAALMEEFAKLTQSLWTSVNIEAISPSDFRSEIQRVAPKFVGCNQQDAQEFLRSLLDGLH-------NEVNRVTVRPRSSVEDFDHYSDE-EKSKRMWNLYLARE-DSKVVDLFVGQLKSSLTCTVCGFRSTMFDPFWDLSIPIAQERPGEVTLKDCLRLFTKEDVLDGEEKPTCNKCKARRKCTKRFSIQKFPQILVIHLKRFSDSNSRSSKLSTFVNFPLKELDLREF-SADNSEHPV----YNLYAVSNHTGNTLGGHYTAYCRNPALGEWYSYNDSRVSPISSGQVRTSNAYVLFYE 387          

Query:  395 LSWRPEIKDLHLLKYVTPLESSLDCKPTRGLV---NMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLAC--EMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLA----GYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYD-CGVHTSRHLEIFRDLSLEIFRN--GSVSLEASFRSYFGTERMKDALCSTCLKLGA----TKQYSLFQLPNIFSVHLKR---CHANSKVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRT-EANIWCLCDDQNVHHVPITEVLQSDA 1450
            L+W P  + L      +P  +S + K T+GLV   N+GNTCF+N ++Q L++T +LRD+ L +LHR      SR   A   E  ++ Q ++   +   + +       +Q+Q  A    GYNQ DA E    +L  LH       N+VN +         D    QD   G  +  S  VE + D  +   F+  L+S +    CG   S   + F DLSL I +   G VSL    R +   + +      TC +  A    TK++ + + P I  +HLKR       SK++T V+FP ++LDL  F S   T+       Y+LY+V NH G    GHYT Y R   +  W   +D  V   P++   + D 
Sbjct:  231 LTWEPSSEGLP----ESPNRTSTNSKSTQGLVGLKNLGNTCFMNSILQCLSNTQSLRDYCLHNLHRRDLNNNSRTNTALMEEFAKLIQTLW---TSSSSEAVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLH-------NEVNRVSVRPRGTAEDFDHLQDEEKG-KKMWSKYVERE-DSKIVDLFVGQLKSSLTCSHCGF-CSTVFDPFWDLSLPISKKSYGEVSLMDCMRLFTKEDVLDGDEKPTCYRCKARRRCTKKFRIQKFPKILVLHLKRFSEARRTSKLSTFVNFPLKDLDLREFASGNSTNA-----MYNLYAVSNHSGTTMGGHYTAYCRNPNSGEWYTFNDSRV--TPMSSRAEGDG 579          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFL-----LSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQV----NEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKD---ALCSTCLK-LGATKQYSLFQLPNIFSVHLKR----CHANSKVNTKVDFP-EELDLAPF-ISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEAN-IWCLCDDQNVHHVPITEVLQSDAYMLFY 1465
            GL N+GNTC++N ++Q L +TPA+ ++      L D++R   +   +   A E   I + ++  +    +  +    I       AGY+Q D+ EL L ++  LH  L+  +N+      E   LD Q  AD + S+  +   S             I+   F    +S +        SR  E F  LSL +      SL+   R +   E++ D     C  C     +TK+  ++++P I  VHLKR         K+ T VDFP + LDL  + I  KQT K     +Y LY V NH G    GHYT Y +      W   DD  V  +  + V  S AY+LFY
Sbjct:  747 GLRNLGNTCYMNSILQCLCNTPAMAEYFNSNYYLEDINRS-NILGHKGEFAEEFGVIMKALWAGLYKCISPRDFKITIGKINDQFAGYDQQDSQELLLFLMDGLHEDLNKADNKKRYKEEENDHLDDQTAADLAWSKHKLLNES-------------IIVALFQGQFKSTVQCSTCHRKSRTFETFMYLSLPLASTSKCSLQDCLRLFSKEEKLTDNNKVFCRHCKAHRDSTKKLEIWKVPPILLVHLKRFSYEGRWKQKLQTTVDFPLDNLDLTQYVIGPKQTLK-----RYYLYGVSNHYGGLDGGHYTAYCKNATKQRWYKFDDHEVSEISTSSVKSSAAYILFY 1075          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEM----IRI---TQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKDA---LCSTCLKL-GATKQYSLFQLPNIFSVHLKRC--HANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQN-SSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFY 1465
            GL NMGNTCFLN  +Q LT+TP L + +LS  H   T ++   C+ C M    I++   +  + KP+ V   L  +        +     +Q DAHE        L   + A +        LD Q  A                           +HQ F   L S++        S   + F D++LEI    SVS   +   +   E++       C+ C K+  A+K++++ + PN+ ++ LKR       K+   V +PE LDL PF+S  Q +       Y LY+V+ H G +  +GHY  Y++     W   +D +V    I  VL   AY+LFY
Sbjct:   97 GLQNMGNTCFLNSALQCLTYTPPLANHMLSREHS-KTCQEPGFCMMCTMQNHIIQVFANSGNVIKPIGVLNELKRI-------AKHFRYGSQEDAHEF-------LRYTVDAMQKSCLPGTKLDRQTQAT------------------------TFIHQVFGGYLRSRVKCLSCKAVSDTFDPFLDITLEIKMAPSVS--KALEQFVKPEQLDGENAYKCTKCKKMVTASKRFTIHRSPNVLTLSLKRFANFTGGKITKDVKYPESLDLRPFMSQSQGE----PQNYGLYAVLVHSGFSCHAGHYFCYIKASNGQWYQMNDSSVSVSDIRSVLNQQAYVLFY 393          

Query:   17 MACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKASFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDLSWRPEIKDLHLLKYVTPLESSLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKDALCSTCLKLGATKQYSLFQLPNIFSVHLKRCHANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSLVMKSN 1495
            MACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKASFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDLSWRPEIKDLHLLKYVTPLESSLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSAREN                   QDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKDALCSTCLKLGATKQYSLFQLPNIFSVHLKRCHANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSLVMKSN
Sbjct:    1 MACSHLNIFFENQTNKLAVKRLISAVVFPLSEQEFKLKASFICKKCAYHKSCLSDSMVCAHCIFSACRKNKHIEDHYREKGHEICVSLELGEMYCNQCQDYQYHEYSEQIIKEFRRLYFANFAMFDLSWRPEIKDLHLLKYVTPLESSLDCKPTRGLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSAREN-------------------QDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKDALCSTCLKLGATKQYSLFQLPNIFSVHLKRCHANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSLVMKSN 474          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLS-----DLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSAREN------QVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRN-GSVSLEASFRSYFGTERMKDA---LCSTCL-KLGATKQYSLFQLPNIFSVHLKR--CHAN--SKVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRT-EANIWCLCDDQNVHHVPITEVLQSDAYMLFYHKNSL 1480
            GL NMGNTC++N V+QAL++T  L +++L+     D++R   +      +  E   +   ++       + S+   +I  + +   G  QHD+ E  L +L  LH  L+           VNE +  DI+       +   IN              D ++ + F     SK+  D    TS   + F  LSL +  N    SLE   + +   ERM  A    C  C     A K+  +++LP    +HLKR  C      K+NT VDFP E   L   +  K T +    D Y LY+V NH G   SGHYT + +  +AN W   DD  V  +   +V     Y+LFY   +L
Sbjct:  630 GLRNMGNTCYMNSVVQALSNTKFLTNYILTNSYQHDINRDNPLGYGGE-IVIEFAYLITALWTGNYREVSPSDFKRMIDGKNEMFRGSEQHDSQEFLLFLLDGLHEDLNRGSKLSKVTLPVNEDKITDIERANQSWKTHIAIN--------------DSVIVRIFQGQYRSKVTCDHCQMTSVTFDAFMYLSLPLVANHNRCSLEDCLKLFLAEERMTGASQWFCPKCKSNRNAKKKIDIWKLPPYLLIHLKRFSCTGQYRQKLNTFVDFPMESFSLVDIL--KHTKQPQKHDTYHLYAVSNHHGNMESGHYTSFCKNMKANEWHNYDDDVVTKIRECDVKTPSGYILFYESYNL 967          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRC---PTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAG----YNQHDAHELFLAILSLLHNHLSA--RENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKI-VYDCGVHTSRHLEIFRDLSLEI--FRNGSVSLEASFRSYFGTERMKDA----LCSTC-LKLGATKQYSLFQLPNIFSVHLKRCHAN---SKVNTKVDFP-EELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVY-VRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYH 1468
            GLVN+GNTCF+N V+Q L++   L+++ LS+ +     P  K S   L      + + I+K  S  Y   +    I+   Q LA      +Q D+ E    +L  LH  ++   R+++   I   + + L+D   ++             ++ D D  +   F+  L+S +    CG + S   + F DLSL I       +SL     S F +E + D      C  C  K   TK++S+ + P++  +HLKR   +   SK+++ ++FP   L+L  +      + S +   Y+LY+V NH G    GHYT Y     +  W   DD  V+ V  T V  ++AY+LFY 
Sbjct:  281 GLVNLGNTCFMNSVLQCLSNCKPLQEYCLSNKYEADLNPNSK-SNGSLFKSYAELMKSIWKSDSESYVSPDKFKRIF---QKLAPAFHVTSQQDSQEFLRLMLEGLHQDVNKVRRKSKSIPITDEESEKLSDKELAELYW-------GRYIKVD-DSFIVDLFVGQLKSTLRCNKCG-YRSITFDPFWDLSLPIPKINRNQISLTDCL-SLFTSEEILDGDEMPKCFKCKTKRPCTKRFSIHKFPSVLVIHLKRFSGDRYRSKISSFIEFPTRNLNLQSY-----AEPSTFA-TYNLYAVSNHSGTVDGGHYTAYCCNPSSKNWYKYDDTRVYKVNETNVCSTEAYVLFYQ 611          

Query:  485 LVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSRNCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQV-QDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCDCIVHQAFMATLESKIVYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMKDALC--STCLKLGATKQYSLFQ-LPNIFSVHLKRCHANSKVNTKVD--FPEELDLAPF------------ISSKQTDKSLWEDKYSLYSVINHRGQNSSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQSDAYMLFYHK 1471
            L N+G  C+LN V+QA++ + A  D ++  LH         N  + E +    ++ +  ++     NL  +   Q+ ++     Q D  EL   +L+ +++ +   +  +NEI + ++    + S     I       S  +  +C  +V     + L            + H+ I  D      +   + L++    + G   + +  C  + C+K  A ++  L + LPN   +HL+R   N K   K+D  F E  +L  F            + + Q D  ++ D+Y L S I HRG    GHY  Y ++  N W L +D  V  V + ++L   AY+LFY K
Sbjct:   34 LRNIGTNCYLNSVLQAISSSSAFVDGIVQ-LH--------ENYGSLEKLEFFTDLIQ--NIHSGNQNLKDISKHQIFKNWNKSGQQDCFELLSYVLNQVYSEIRKYKETMNEIETKNLLEWLNQSLPMRII------VSYTIRCECGNLVDVPLHSEL------------ALHVPIISD------KKQPIELQSLVDQFLGDNEITNYECYSNKCIKTKALRETKLVKPLPNTICLHLQRTFWNGKTMKKIDKIFAETENLDLFVRNYVETIIETSVKAIQNDCEVYGDEYRLTSFIVHRGSVKGGHYVCY-KSMRNRWFLTNDNQVKPVELHKILNCQAYLLFYEK 344          

Query:  482 GLVNMGNTCFLNVVIQALTHTPALRDFLLSDLHRCPTVKQSR--NCLACEMIRITQEIYKPVSVPYALSNLLYVIWSQVQDLAGYNQHDAHELFLAILSLLHNHLSARENQVNEIRSLDIQALADPSCSQDTINGSSRSSSTGVEDDCD--------CIVHQAFMATLESKI-VYDCGVHTSRHLEIFRDLSLEIFRNGSVSLEASFRSYFGTERMK---DALCST-CLKLGATKQYSLFQLPNIFSVHLKR------CHANSKVNTKVDFPEELDLAPFISSKQTDKSLWEDKYSLYSVINHRGQN-SSGHYTVYVRTEANIWCLCDDQNVHHVPITEVLQ------------SDAYMLFYH 1468
            GLVN GNTC+ N V+QAL      R+ LL    +    K+    +CLA     IT +  K   +  A    +  +  + +    + Q DAHE    +L           NQ+ +I   + QA  +     + IN    S ST V+ D D          +H+ F  TL ++    +C    ++  E F DLS+++ +N S+S     + +  TE M+      C   C K  A K+  + +LP + ++HLKR       + ++K++ +V FP EL L  F +S   D       Y L +V+ H G   + GHY   +++   +W L DD  V  +  T + +              AY+LFY 
Sbjct:   32 GLVNFGNTCYCNSVLQALFFCRPFRENLLQYKQQTKGQKKETLLSCLADLFHSITTQKKKVGQI--APKKFIQRLKRENELFDNFLQQDAHEFLNYLL-----------NQIADILIAEKQATLN-----NQINNKYISESTIVDGDADKTDQAKITTWIHEIFQGTLTNETRCLNCESERTKD-EDFLDLSVDVEQNTSIS--HCLQCFSNTETMQFDNKYYCEVCCCKQEAQKRMRVKKLPILLALHLKRFKYIEHLNRSTKLSYRVAFPMELRL--FNTSD--DAYNAHRLYDLTAVVVHCGSGLNRGHYITLIKSYG-LWLLFDDDIVEKIDPTNIEEFFGLSTEATKTSESAYILFYQ 368