Cysteine dioxygenase

Overview
NameCysteine dioxygenase
Smed IDSMED30002370
Length (bp)939
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cysteine dioxygenase (SMED30002370) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cysteine dioxygenase (SMED30002370) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30002370

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
cephalic gangliaSMED30002370h1SMcG0007097 dd_Smed_v4_3640_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30002370h1SMcG0007097 dd_Smed_v4_3640_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Human
Match: CDO1 (cysteine dioxygenase type 1 [Source:HGNC Symbol;Acc:HGNC:1795])

HSP 1 Score: 181.03 bits (458), Expect = 9.602e-56
Identity = 89/182 (48.90%), Postives = 121/182 (66.48%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            TL +LI  +HQ F   + ++ ++Q IME+Y S   EW  YA  ++         YTR+LVD GNG FNLMIL W + HGSSIH H+NS+C +K+L+G+LKE+ + WP  K+  M  +S+  L+EN+ +YI D IGLHRVEN SHT+ AVSLHLY PPFD    FD+ TG     +M+FH+ +
Sbjct:   11 TLADLIRILHQLFAGDEVNVEEVQAIMEAYESDPTEWAMYAKFDQYR-------YTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTNSHCFLKMLQGNLKETLFAWPDKKSNEMVKKSERVLRENQCAYINDSIGLHRVENISHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKF 185
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Celegans
Match: cdo-1 (Cysteine dioxygenase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q20893])

HSP 1 Score: 152.14 bits (383), Expect = 4.032e-45
Identity = 71/183 (38.80%), Postives = 115/183 (62.84%), Query Frame = 1 
Query:  106 LTLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            ++  +L+  + + F+    D+ ++ K+M SY S   EW+++A  +  +       YTR+LVD GNG +NLMIL W     SS+H H++++C +K+L+G L E++Y WP+ ++ P+ +        N VSY+ DE+GLHR+EN SH++ AVSLHLY PP+     FDE TGK    +++F++ Y
Sbjct:    2 ISFVQLVVQIREIFQQKLIDVDEVMKLMASYKSNANEWRRFAIFDMNK-------YTRNLVDVGNGKYNLMILCWGPGMASSVHDHTDAHCFVKILDGELTETKYAWPRKRHVPLDISENKTYGMNGVSYMNDELGLHRMENLSHSNGAVSLHLYIPPYSTCNAFDERTGKKTQCTVTFYSKY 177
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Celegans
Match: cdo-1 (Cysteine dioxygenase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q20893])

HSP 1 Score: 152.14 bits (383), Expect = 4.032e-45
Identity = 71/183 (38.80%), Postives = 115/183 (62.84%), Query Frame = 1 
Query:  106 LTLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            ++  +L+  + + F+    D+ ++ K+M SY S   EW+++A  +  +       YTR+LVD GNG +NLMIL W     SS+H H++++C +K+L+G L E++Y WP+ ++ P+ +        N VSY+ DE+GLHR+EN SH++ AVSLHLY PP+     FDE TGK    +++F++ Y
Sbjct:    2 ISFVQLVVQIREIFQQKLIDVDEVMKLMASYKSNANEWRRFAIFDMNK-------YTRNLVDVGNGKYNLMILCWGPGMASSVHDHTDAHCFVKILDGELTETKYAWPRKRHVPLDISENKTYGMNGVSYMNDELGLHRMENLSHSNGAVSLHLYIPPYSTCNAFDERTGKKTQCTVTFYSKY 177
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Fly
Match: CG5493 (gene:FBgn0034364 transcript:FBtr0086713)

HSP 1 Score: 154.451 bits (389), Expect = 2.949e-45
Identity = 80/185 (43.24%), Postives = 120/185 (64.86%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWP--------KSKNEPMALQSK--VYLKE-----NEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGK 618
            +L +L++ +H+EFE+   ++  +  +M SY S   EW+KYA  ++        +YTR+LVD+GNG FNL+IL W + HGSS+H H++S+C MK+L+G L+E RY++P        +S +    + S+  V + E     N+V+YI D +GLHRVENPSH+D +VSLHLY PPFD   +F +N  K
Sbjct:   41 SLSDLVAALHREFESNYVNIEMVNHLMLSYKSNPREWRKYAKFDRY-------TYTRNLVDAGNGKFNLLILCWGEGHGSSVHDHADSHCFMKMLKGDLREKRYEYPNRSARDNGRSHHPDGEIDSRELVEIGETPIAVNDVAYINDNLGLHRVENPSHSDTSVSLHLYCPPFDTCSVFQDNLKK 218
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Fly
Match: CG5493 (gene:FBgn0034364 transcript:FBtr0307348)

HSP 1 Score: 154.451 bits (389), Expect = 2.949e-45
Identity = 80/185 (43.24%), Postives = 120/185 (64.86%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWP--------KSKNEPMALQSK--VYLKE-----NEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGK 618
            +L +L++ +H+EFE+   ++  +  +M SY S   EW+KYA  ++        +YTR+LVD+GNG FNL+IL W + HGSS+H H++S+C MK+L+G L+E RY++P        +S +    + S+  V + E     N+V+YI D +GLHRVENPSH+D +VSLHLY PPFD   +F +N  K
Sbjct:   41 SLSDLVAALHREFESNYVNIEMVNHLMLSYKSNPREWRKYAKFDRY-------TYTRNLVDAGNGKFNLLILCWGEGHGSSVHDHADSHCFMKMLKGDLREKRYEYPNRSARDNGRSHHPDGEIDSRELVEIGETPIAVNDVAYINDNLGLHRVENPSHSDTSVSLHLYCPPFDTCSVFQDNLKK 218
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Fly
Match: CG5493 (gene:FBgn0034364 transcript:FBtr0307347)

HSP 1 Score: 154.451 bits (389), Expect = 2.949e-45
Identity = 80/185 (43.24%), Postives = 120/185 (64.86%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWP--------KSKNEPMALQSK--VYLKE-----NEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGK 618
            +L +L++ +H+EFE+   ++  +  +M SY S   EW+KYA  ++        +YTR+LVD+GNG FNL+IL W + HGSS+H H++S+C MK+L+G L+E RY++P        +S +    + S+  V + E     N+V+YI D +GLHRVENPSH+D +VSLHLY PPFD   +F +N  K
Sbjct:   41 SLSDLVAALHREFESNYVNIEMVNHLMLSYKSNPREWRKYAKFDRY-------TYTRNLVDAGNGKFNLLILCWGEGHGSSVHDHADSHCFMKMLKGDLREKRYEYPNRSARDNGRSHHPDGEIDSRELVEIGETPIAVNDVAYINDNLGLHRVENPSHSDTSVSLHLYCPPFDTCSVFQDNLKK 218
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Fly
Match: CG5493 (gene:FBgn0034364 transcript:FBtr0307349)

HSP 1 Score: 154.451 bits (389), Expect = 2.949e-45
Identity = 80/185 (43.24%), Postives = 120/185 (64.86%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWP--------KSKNEPMALQSK--VYLKE-----NEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGK 618
            +L +L++ +H+EFE+   ++  +  +M SY S   EW+KYA  ++        +YTR+LVD+GNG FNL+IL W + HGSS+H H++S+C MK+L+G L+E RY++P        +S +    + S+  V + E     N+V+YI D +GLHRVENPSH+D +VSLHLY PPFD   +F +N  K
Sbjct:   41 SLSDLVAALHREFESNYVNIEMVNHLMLSYKSNPREWRKYAKFDRY-------TYTRNLVDAGNGKFNLLILCWGEGHGSSVHDHADSHCFMKMLKGDLREKRYEYPNRSARDNGRSHHPDGEIDSRELVEIGETPIAVNDVAYINDNLGLHRVENPSHSDTSVSLHLYCPPFDTCSVFQDNLKK 218
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Zebrafish
Match: cdo1 (cysteine dioxygenase, type I [Source:NCBI gene;Acc:393714])

HSP 1 Score: 169.474 bits (428), Expect = 1.670e-51
Identity = 89/198 (44.95%), Postives = 123/198 (62.12%), Query Frame = 1 
Query:   97 MNKLTLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSK-NEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYNGQDSVILNTS 687
            M   TL +LI  +HQ F++   ++ ++Q +MESY S   +W K+A  ++         YTR+LVD GNG FNLMIL W + HGSSIH H++S+C +KLL+G LKE+ + WP  K    M  + +  L+EN+ +YI D +GLHRVEN SHT+ AVSLHLY PPF   R FD+ TG      M+F + Y  +    L+ S
Sbjct:    9 MKPETLEDLIKTLHQIFQSDSINVEEVQNLMESYQSNPQDWMKFAKFDQ-------YRYTRNLVDEGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGQLKETLFDWPDRKLQSGMKPRGQSVLQENQCAYINDSLGLHRVENVSHTEPAVSLHLYSPPFQSCRTFDQRTGHHNTVKMTFWSKYGERTPYELSVS 199
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Zebrafish
Match: cdo1 (cysteine dioxygenase, type I [Source:NCBI gene;Acc:393714])

HSP 1 Score: 169.474 bits (428), Expect = 1.847e-51
Identity = 89/198 (44.95%), Postives = 123/198 (62.12%), Query Frame = 1 
Query:   97 MNKLTLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSK-NEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYNGQDSVILNTS 687
            M   TL +LI  +HQ F++   ++ ++Q +MESY S   +W K+A  ++         YTR+LVD GNG FNLMIL W + HGSSIH H++S+C +KLL+G LKE+ + WP  K    M  + +  L+EN+ +YI D +GLHRVEN SHT+ AVSLHLY PPF   R FD+ TG      M+F + Y  +    L+ S
Sbjct:    7 MKPETLEDLIKTLHQIFQSDSINVEEVQNLMESYQSNPQDWMKFAKFDQ-------YRYTRNLVDEGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGQLKETLFDWPDRKLQSGMKPRGQSVLQENQCAYINDSLGLHRVENVSHTEPAVSLHLYSPPFQSCRTFDQRTGHHNTVKMTFWSKYGERTPYELSVS 197
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Xenopus
Match: gjd2 (gap junction protein delta 2 [Source:Xenbase;Acc:XB-GENE-489803])

HSP 1 Score: 177.948 bits (450), Expect = 1.280e-54
Identity = 93/183 (50.82%), Postives = 123/183 (67.21%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSK-NEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            TL ELI  +H+ F + K ++ ++Q I+ESY S   EW K+A  ++         YTR+LVD GNG FNLMIL W + HGSSIH H+NS+C +K+L+GSLKE+ Y+WPK K N  M  +++  LK N+ +YI D IGLHRVENPSHT+ AVSLHLY PPF+    FD+ TG      M+F + Y
Sbjct:   11 TLDELIQILHEIFASDKVNIEEVQAIVESYESNPREWMKFAKFDQYR-------YTRNLVDEGNGKFNLMILCWGEGHGSSIHDHANSHCFLKILQGSLKETLYEWPKKKSNTEMVKKAEGVLKLNQCAYINDSIGLHRVENPSHTEPAVSLHLYSPPFNECHTFDQRTGHTNSVKMTFWSKY 186
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Mouse
Match: Cdo1 (cysteine dioxygenase 1, cytosolic [Source:MGI Symbol;Acc:MGI:105925])

HSP 1 Score: 176.407 bits (446), Expect = 4.172e-54
Identity = 86/182 (47.25%), Postives = 121/182 (66.48%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            TL +LI  +H+ F   + ++ ++Q ++E+Y S   EW  YA  ++         YTR+LVD GNG FNLMIL W + HGSSIH H++S+C +KLL+G+LKE+ + WP  K+  M  +S+  L+EN+ +YI D IGLHRVEN SHT+ AVSLHLY PPFD    FD+ TG     +M+FH+ +
Sbjct:   11 TLADLIRILHELFAGDEVNVEEVQAVLEAYESNPAEWALYAKFDQYR-------YTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERTLRENQCAYINDSIGLHRVENVSHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKF 185
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Mouse
Match: Cdo1 (cysteine dioxygenase 1, cytosolic [Source:MGI Symbol;Acc:MGI:105925])

HSP 1 Score: 148.288 bits (373), Expect = 5.549e-44
Identity = 76/150 (50.67%), Postives = 99/150 (66.00%), Query Frame = 1 
Query:  193 SYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSF 642
            +Y S   EW  YA  ++         YTR+LVD GNG FNLMIL W + HGS IH H++S+C +KLL+G+LKE+ + WP  K+  M  +S+  L+EN+ +YI D IGLHRVEN SHT+ AVSLHLY PPFD    FD+ TG     +M+F
Sbjct:    2 AYESNPAEWALYAKFDQYR-------YTRNLVDQGNGKFNLMILCWGEGHGS-IHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERTLRENQCAYINDSIGLHRVENVSHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTF 143
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Mouse
Match: Cdo1 (cysteine dioxygenase 1, cytosolic [Source:MGI Symbol;Acc:MGI:105925])

HSP 1 Score: 127.872 bits (320), Expect = 9.531e-36
Identity = 69/182 (37.91%), Postives = 100/182 (54.95%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            TL +LI  +H+ F   + ++ ++Q ++E+Y S   EW  YA                                 K    SSIH H++S+C +KLL+G+LKE+ + WP  K+  M  +S+  L+EN+ +YI D IGLHRVEN SHT+ AVSLHLY PPFD    FD+ TG     +M+FH+ +
Sbjct:   11 TLADLIRILHELFAGDEVNVEEVQAVLEAYESNPAEWALYA---------------------------------KFDQYSSIHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERTLRENQCAYINDSIGLHRVENVSHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKF 159
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Mouse
Match: Cdo1 (cysteine dioxygenase 1, cytosolic [Source:MGI Symbol;Acc:MGI:105925])

HSP 1 Score: 115.546 bits (288), Expect = 2.804e-31
Identity = 56/130 (43.08%), Postives = 85/130 (65.38%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYI 498
            TL +LI  +H+ F   + ++ ++Q ++E+Y S   EW  YA  ++         YTR+LVD GNG FNLMIL W + HGSSIH H++S+C +KLL+G+LKE+ + WP  K+  M  +S+  L+EN+ +YI
Sbjct:   11 TLADLIRILHELFAGDEVNVEEVQAVLEAYESNPAEWALYAKFDQYR-------YTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERTLRENQCAYI 133
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Mouse
Match: Cdo1 (cysteine dioxygenase 1, cytosolic [Source:MGI Symbol;Acc:MGI:105925])

HSP 1 Score: 63.5438 bits (153), Expect = 1.961e-12
Identity = 32/79 (40.51%), Postives = 47/79 (59.49%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHG 345
            TL +LI  +H+ F   + ++ ++Q ++E+Y S   EW  YA  ++         YTR+LVD GNG FNLMIL W + HG
Sbjct:   11 TLADLIRILHELFAGDEVNVEEVQAVLEAYESNPAEWALYAKFDQYR-------YTRNLVDQGNGKFNLMILCWGEGHG 82
[Close]
BLAST of Cysteine dioxygenase vs. UniProt/SwissProt
Match: sp|Q5RBQ7|CDO1_PONAB (Cysteine dioxygenase type 1 OS=Pongo abelii OX=9601 GN=CDO1 PE=2 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 4.611e-55
Identity = 89/182 (48.90%), Postives = 121/182 (66.48%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            TL +LI  +HQ F   + ++ ++Q IME+Y S   EW  YA  ++         YTR+LVD GNG FNLMIL W + HGSSIH H+NS+C +K+L+G+LKE+ + WP  K+  M  +S+  L+EN+ +YI D IGLHRVEN SHT+ AVSLHLY PPFD    FD+ TG     +M+FH+ +
Sbjct:   11 TLADLIRILHQLFAGDEVNVEEVQAIMEAYESDPTEWAMYAKFDQYR-------YTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTNSHCFLKMLQGNLKETLFAWPDKKSNEMVKKSERVLRENQCAYINDSIGLHRVENISHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKF 185
[Close]
BLAST of Cysteine dioxygenase vs. UniProt/SwissProt
Match: sp|Q16878|CDO1_HUMAN (Cysteine dioxygenase type 1 OS=Homo sapiens OX=9606 GN=CDO1 PE=1 SV=2)

HSP 1 Score: 181.03 bits (458), Expect = 4.611e-55
Identity = 89/182 (48.90%), Postives = 121/182 (66.48%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            TL +LI  +HQ F   + ++ ++Q IME+Y S   EW  YA  ++         YTR+LVD GNG FNLMIL W + HGSSIH H+NS+C +K+L+G+LKE+ + WP  K+  M  +S+  L+EN+ +YI D IGLHRVEN SHT+ AVSLHLY PPFD    FD+ TG     +M+FH+ +
Sbjct:   11 TLADLIRILHQLFAGDEVNVEEVQAIMEAYESDPTEWAMYAKFDQYR-------YTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTNSHCFLKMLQGNLKETLFAWPDKKSNEMVKKSERVLRENQCAYINDSIGLHRVENISHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKF 185
[Close]
BLAST of Cysteine dioxygenase vs. UniProt/SwissProt
Match: sp|Q3SZU4|CDO1_BOVIN (Cysteine dioxygenase type 1 OS=Bos taurus OX=9913 GN=CDO1 PE=2 SV=1)

HSP 1 Score: 177.178 bits (448), Expect = 1.299e-53
Identity = 87/182 (47.80%), Postives = 120/182 (65.93%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            TL +LI  +HQ F   + ++ ++Q +ME+Y S   EW  YA  ++         YTR+LVD GNG FNLMIL W + HGSSIH H++S+C +K+L+G+LKE+ + WP  K+  M  +S+  L+EN+ +YI D IGLHRVEN SHT+ AVSLHLY PPFD    FD+ TG      M+FH+ +
Sbjct:   11 TLADLIRVLHQLFAGEEINVEEVQAVMEAYESNPAEWAVYAKFDQYR-------YTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKMLQGNLKETLFAWPDKKSNEMIKKSERILRENQCAYINDSIGLHRVENISHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVIMTFHSKF 185
[Close]
BLAST of Cysteine dioxygenase vs. UniProt/SwissProt
Match: sp|P21816|CDO1_RAT (Cysteine dioxygenase type 1 OS=Rattus norvegicus OX=10116 GN=Cdo1 PE=1 SV=1)

HSP 1 Score: 176.407 bits (446), Expect = 2.918e-53
Identity = 86/182 (47.25%), Postives = 121/182 (66.48%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            TL +LI  +H+ F   + ++ ++Q ++E+Y S   EW  YA  ++         YTR+LVD GNG FNLMIL W + HGSSIH H++S+C +KLL+G+LKE+ + WP  K+  M  +S+  L+EN+ +YI D IGLHRVEN SHT+ AVSLHLY PPFD    FD+ TG     +M+FH+ +
Sbjct:   11 TLADLIRILHELFAGDEVNVEEVQAVLEAYESNPAEWALYAKFDQYR-------YTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERTLRENQCAYINDSIGLHRVENVSHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKF 185
[Close]
BLAST of Cysteine dioxygenase vs. UniProt/SwissProt
Match: sp|P60334|CDO1_MOUSE (Cysteine dioxygenase type 1 OS=Mus musculus OX=10090 GN=Cdo1 PE=1 SV=1)

HSP 1 Score: 176.407 bits (446), Expect = 2.918e-53
Identity = 86/182 (47.25%), Postives = 121/182 (66.48%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            TL +LI  +H+ F   + ++ ++Q ++E+Y S   EW  YA  ++         YTR+LVD GNG FNLMIL W + HGSSIH H++S+C +KLL+G+LKE+ + WP  K+  M  +S+  L+EN+ +YI D IGLHRVEN SHT+ AVSLHLY PPFD    FD+ TG     +M+FH+ +
Sbjct:   11 TLADLIRILHELFAGDEVNVEEVQAVLEAYESNPAEWALYAKFDQYR-------YTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERTLRENQCAYINDSIGLHRVENVSHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKF 185
[Close]
BLAST of Cysteine dioxygenase vs. TrEMBL
Match: A0A2I4ARF8 (Cysteine dioxygenase OS=Austrofundulus limnaeus OX=52670 GN=cdo1 PE=3 SV=1)

HSP 1 Score: 186.037 bits (471), Expect = 1.605e-54
Identity = 96/186 (51.61%), Postives = 127/186 (68.28%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNE-PMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYNGQ 663
            TL ELI  +H+ FEN   ++ ++Q IMESY S   EW+KYA  ++         YTR+LVD GNG FNLMIL W + HGSSIH H+NS+C MKLL+G LKE+ ++WP SK+   M  +S+  L+EN+V+YI+D IGLHRVEN SHT+ AVSLHLY PPF+  + FD+ TG      M+F + Y  +
Sbjct:   11 TLDELIKILHEIFENDNINVEEVQNIMESYESKPHEWRKYAKFDQ-------YRYTRNLVDEGNGKFNLMILCWGEGHGSSIHDHTNSHCFMKLLQGQLKETLFQWPDSKSHGDMVQKSQRILQENKVAYISDTIGLHRVENVSHTECAVSLHLYSPPFETCQTFDQRTGHKNTVKMTFWSKYGAR 189
[Close]
BLAST of Cysteine dioxygenase vs. TrEMBL
Match: A0A2K5D212 (Cysteine dioxygenase OS=Aotus nancymaae OX=37293 GN=CDO1 PE=3 SV=1)

HSP 1 Score: 183.726 bits (465), Expect = 1.150e-53
Identity = 89/182 (48.90%), Postives = 122/182 (67.03%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            TL +LI  +HQ F   + ++ ++Q IME+Y S   EW  YA  ++         YTR+LVD GNG FNLMIL W + HGSSIH H+NS+C +K+L+G+LKE+ + WP  K+  M  +S+  L+EN+ +YI D IGLHRVEN SHT++AVSLHLY PPFD    FD+ TG     +M+FH+ +
Sbjct:   11 TLADLIRILHQLFAGDEVNVEEVQAIMEAYESDPAEWAMYAKFDQYR-------YTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTNSHCFLKMLQGNLKETLFAWPDKKSNEMVKKSERVLRENQCAYINDSIGLHRVENISHTELAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKF 185
[Close]
BLAST of Cysteine dioxygenase vs. TrEMBL
Match: A0A3Q1IZP5 (Cysteine dioxygenase OS=Anabas testudineus OX=64144 PE=3 SV=1)

HSP 1 Score: 182.956 bits (463), Expect = 2.124e-53
Identity = 99/202 (49.01%), Postives = 129/202 (63.86%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNE-PMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYNGQDSVILNTSVPIVPDNN 711
            TL +LI  +H+ FE+   ++ ++Q IMESY S   EW KYA  ++         YTR+LVD GNG FNLMIL W + HGSSIH H+NS+C MKLL+G LKE+ +KWP SK+   M  +S+  L+EN+V+YI D IGLHRVEN SHT+ AVSLHLY PPF   + FD+ TG      M+F + +  + S     S     DNN
Sbjct:   11 TLDDLIKTLHKIFESDCINVEEVQDIMESYESKPQEWMKYAKFDQ-------YRYTRNLVDEGNGKFNLMILCWGEGHGSSIHDHTNSHCFMKLLQGQLKETLFKWPDSKSHGEMIQRSQRILQENKVAYINDSIGLHRVENVSHTECAVSLHLYSPPFQTCQTFDQRTGHKNAVKMTFWSKFGERTSFAATVS---CDDNN 202
[Close]
BLAST of Cysteine dioxygenase vs. TrEMBL
Match: A0A3Q2GHC7 (Cysteine dioxygenase OS=Cyprinodon variegatus OX=28743 PE=3 SV=1)

HSP 1 Score: 182.57 bits (462), Expect = 3.203e-53
Identity = 93/182 (51.10%), Postives = 123/182 (67.58%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            TL ELI+ +H+ FE+   ++ ++Q IMESY S   EW KYA  ++         YTR+LVD GNG FNLMIL W + HGSSIH H++S+C MKLL+G LKE+ + WP  K+  M  +S+  L+EN+V+YI D IGLHRVEN SHT+ AVSLHLY PPF+  + FD+ TG      M+F + Y
Sbjct:   14 TLDELIAILHKIFESDCINVEEVQNIMESYESKPHEWMKYAKFDQ-------YRYTRNLVDEGNGKFNLMILCWGEGHGSSIHDHTDSHCFMKLLQGQLKETLFDWPDRKSHDMVQKSQRILQENKVAYINDSIGLHRVENVSHTECAVSLHLYSPPFETCQTFDQRTGHKNTVKMTFWSKY 188
[Close]
BLAST of Cysteine dioxygenase vs. TrEMBL
Match: A0A2K6MMR8 (Cysteine dioxygenase OS=Rhinopithecus bieti OX=61621 GN=CDO1 PE=3 SV=1)

HSP 1 Score: 182.57 bits (462), Expect = 3.501e-53
Identity = 88/182 (48.35%), Postives = 122/182 (67.03%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            TL +LI  +H+ F   + ++ ++Q +ME+Y S   EW  YA  ++         YTR+LVD GNG FNLMIL W + HGSSIH H+NS+C +K+L+GSLKE+ + WP  K+  M  +S+  L+EN+ +YI D IGLHRVEN SHT++AVSLHLY PPFD    FD+ TG     +M+FH+ +
Sbjct:   11 TLADLIRVLHRLFAGDEVNVEEVQAVMEAYESDPTEWAMYAKFDQYR-------YTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTNSHCFLKMLQGSLKETLFAWPDKKSNEMVKKSERVLRENQCAYINDSIGLHRVENISHTELAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKF 185
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Cavefish
Match: cdo1 (cysteine dioxygenase type 1 [Source:NCBI gene;Acc:103041926])

HSP 1 Score: 171.014 bits (432), Expect = 4.201e-52
Identity = 94/202 (46.53%), Postives = 127/202 (62.87%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNE-PMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYNGQDSVILNTSVPIVPDNN 711
            TL +LI  +H+ FE+   ++ ++Q IME+Y S   EW K+A  ++         YTR+LVD GNG FNLMIL W + HGSSIH H+ S+C MKLL+G LKE+ ++WP  K+   M  +S+  L EN+ +YI D IGLHRVEN SHT+ A SLHLY PPF   + FD+ TG      M+F + Y G+ +   NT   I  +NN
Sbjct:   11 TLDDLIKILHKIFEDDHVNIEEVQSIMEAYESNPQEWMKFAKFDQ-------YRYTRNLVDEGNGKFNLMILCWGEGHGSSIHDHAESHCFMKLLQGQLKETLFEWPDRKSHGDMVQKSQRILLENQCAYINDSIGLHRVENVSHTECAASLHLYSPPFQQCQTFDQRTGHKNTVKMTFWSKY-GERTPFENT---ISQENN 201
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Cavefish
Match: cdo1 (cysteine dioxygenase type 1 [Source:NCBI gene;Acc:103041926])

HSP 1 Score: 126.331 bits (316), Expect = 7.818e-35
Identity = 79/217 (36.41%), Postives = 117/217 (53.92%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYA-FGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNE-PMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYNGQDSVILNTSVPIVPDNN*ISLQ-MDFKVVFY 750
            TL +LI  +H+ FE+   ++ ++Q IME+Y S   EW K+A F + + ++S+              HF             SIH H+ S+C MKLL+G LKE+ ++WP  K+   M  +S+  L EN+ +YI D IGLHRVEN SHT+ A SLHLY PPF   + FD+ TG      M+F + Y  +         P V  NN  + + +D+  ++Y
Sbjct:   11 TLDDLIKILHKIFEDDHVNIEEVQSIMEAYESNPQEWMKFAKFDQYRTVMSSI-------------HF-------------SIHDHAESHCFMKLLQGQLKETLFEWPDRKSHGDMVQKSQRILLENQCAYINDSIGLHRVENVSHTECAASLHLYSPPFQQCQTFDQRTGHKNTVKMTFWSKYGER--------TPFVSLNNMYTTKSLDYIYIYY 193
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Sea Lamprey
Match: cdo1 (cysteine dioxygenase, type I [Source:NCBI gene;Acc:393714])

HSP 1 Score: 160.999 bits (406), Expect = 8.110e-49
Identity = 80/184 (43.48%), Postives = 119/184 (64.67%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKW--PKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            +L ELIS +H+ F   K D+ +++ +M SY     +W+++A  +K         YTR+LVD GNG FNLM+L W + HGSSIH H +++C +K+++G LKE+ Y+W  P +K + +  +S+    E++V+YI D IGLHRVEN SH++ A+SLHLY PPF     FDE TG      M+F++ Y
Sbjct:   15 SLDELISVLHELFSGDKVDVDEVKAVMASYPHDATDWERFAKFDK-------FRYTRNLVDEGNGKFNLMLLCWGEGHGSSIHDHMDAHCFVKIMQGQLKETMYEWPTPSTKKQELIKKSENLYSEDQVTYINDSIGLHRVENVSHSETAISLHLYSPPFSSCHCFDERTGHKNEVQMTFYSKY 191
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Nematostella
Match: EDO40387 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7E6])

HSP 1 Score: 139.043 bits (349), Expect = 4.319e-41
Identity = 63/131 (48.09%), Postives = 89/131 (67.94%), Query Frame = 1 
Query:  271 YTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSK--NEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYN 657
            YTR+LVD GNG FNL++L W +  GSSIH H++S+C +K+L+G LKE+ ++WP      +P+ ++   Y+  +EV+YI D IGLHR+EN SH+D A SLHLY PPFD    FD+ TG      ++F + Y 
Sbjct:    1 YTRNLVDEGNGKFNLIVLCWGEGQGSSIHDHTDSHCFLKVLDGKLKETLFEWPSESEPEKPLDVKGVSYVDRDEVAYINDSIGLHRMENTSHSDTACSLHLYCPPFDMCNSFDQRTGHKRKCKVTFWSKYG 131
[Close]
BLAST of Cysteine dioxygenase vs. Ensembl Medaka
Match: cdo1 (cysteine dioxygenase type 1 [Source:NCBI gene;Acc:101158113])

HSP 1 Score: 181.03 bits (458), Expect = 1.128e-55
Identity = 92/183 (50.27%), Postives = 124/183 (67.76%), Query Frame = 1 
Query:  109 TLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNE-PMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIY 654
            TL ELI  +HQ F++ + ++ ++Q +MESY S   EW+KYA  ++         YTR+LVD GN  FNLMIL W + HGSSIH H+NS+C MKLL+G LKE+ + WP  K++  M  +S+  L+EN+V+YI D IGLHRVEN SHT+ AVSLHLY PPF+  + FD+ TG      M+F + Y
Sbjct:   11 TLDELIKTLHQIFQSDRINVEEVQNLMESYESKPHEWRKYAKFDQ-------YRYTRNLVDKGNDKFNLMILCWGEGHGSSIHDHTNSHCFMKLLQGQLKETLFHWPDGKSQGDMVTKSQRVLQENKVAYINDSIGLHRVENVSHTECAVSLHLYSPPFETCQTFDQRTGHKNTVKMTFWSKY 186
[Close]
BLAST of Cysteine dioxygenase vs. Planmine SMEST
Match: SMESG000030961.1 (SMESG000030961.1)

HSP 1 Score: 426.787 bits (1096), Expect = 7.574e-153
Identity = 204/205 (99.51%), Postives = 205/205 (100.00%), Query Frame = 1 
Query:   97 MNKLTLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYNGQDSVILNTSVPIVPDNN 711
            MNKLTLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRY+WPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYNGQDSVILNTSVPIVPDNN
Sbjct:    1 MNKLTLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYEWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYNGQDSVILNTSVPIVPDNN 205
[Close]
BLAST of Cysteine dioxygenase vs. Planmine SMEST
Match: SMESG000030961.1 (SMESG000030961.1)

HSP 1 Score: 402.905 bits (1034), Expect = 1.154e-143
Identity = 192/193 (99.48%), Postives = 193/193 (100.00%), Query Frame = 1 
Query:  133 MHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYNGQDSVILNTSVPIVPDNN 711
            MHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRY+WPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYNGQDSVILNTSVPIVPDNN
Sbjct:    1 MHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQEIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLEGSLKESRYEWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTDIAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYNGQDSVILNTSVPIVPDNN 193
The following BLAST results are available for this feature:
BLAST of Cysteine dioxygenase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CDO19.602e-5648.90cysteine dioxygenase type 1 [Source:HGNC Symbol;Ac... [more]
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BLAST of Cysteine dioxygenase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
cdo-14.032e-4538.80Cysteine dioxygenase 1 [Source:UniProtKB/Swiss-Pr... [more]
cdo-14.032e-4538.80Cysteine dioxygenase 1 [Source:UniProtKB/Swiss-Pr... [more]
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BLAST of Cysteine dioxygenase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
CG54932.949e-4543.24gene:FBgn0034364 transcript:FBtr0086713[more]
CG54932.949e-4543.24gene:FBgn0034364 transcript:FBtr0307348[more]
CG54932.949e-4543.24gene:FBgn0034364 transcript:FBtr0307347[more]
CG54932.949e-4543.24gene:FBgn0034364 transcript:FBtr0307349[more]
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BLAST of Cysteine dioxygenase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
cdo11.670e-5144.95cysteine dioxygenase, type I [Source:NCBI gene;Acc... [more]
cdo11.847e-5144.95cysteine dioxygenase, type I [Source:NCBI gene;Acc... [more]
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BLAST of Cysteine dioxygenase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
gjd21.280e-5450.82gap junction protein delta 2 [Source:Xenbase;Acc:X... [more]
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BLAST of Cysteine dioxygenase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cdo14.172e-5447.25cysteine dioxygenase 1, cytosolic [Source:MGI Symb... [more]
Cdo15.549e-4450.67cysteine dioxygenase 1, cytosolic [Source:MGI Symb... [more]
Cdo19.531e-3637.91cysteine dioxygenase 1, cytosolic [Source:MGI Symb... [more]
Cdo12.804e-3143.08cysteine dioxygenase 1, cytosolic [Source:MGI Symb... [more]
Cdo11.961e-1240.51cysteine dioxygenase 1, cytosolic [Source:MGI Symb... [more]
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BLAST of Cysteine dioxygenase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5RBQ7|CDO1_PONAB4.611e-5548.90Cysteine dioxygenase type 1 OS=Pongo abelii OX=960... [more]
sp|Q16878|CDO1_HUMAN4.611e-5548.90Cysteine dioxygenase type 1 OS=Homo sapiens OX=960... [more]
sp|Q3SZU4|CDO1_BOVIN1.299e-5347.80Cysteine dioxygenase type 1 OS=Bos taurus OX=9913 ... [more]
sp|P21816|CDO1_RAT2.918e-5347.25Cysteine dioxygenase type 1 OS=Rattus norvegicus O... [more]
sp|P60334|CDO1_MOUSE2.918e-5347.25Cysteine dioxygenase type 1 OS=Mus musculus OX=100... [more]
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BLAST of Cysteine dioxygenase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2I4ARF81.605e-5451.61Cysteine dioxygenase OS=Austrofundulus limnaeus OX... [more]
A0A2K5D2121.150e-5348.90Cysteine dioxygenase OS=Aotus nancymaae OX=37293 G... [more]
A0A3Q1IZP52.124e-5349.01Cysteine dioxygenase OS=Anabas testudineus OX=6414... [more]
A0A3Q2GHC73.203e-5351.10Cysteine dioxygenase OS=Cyprinodon variegatus OX=2... [more]
A0A2K6MMR83.501e-5348.35Cysteine dioxygenase OS=Rhinopithecus bieti OX=616... [more]
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BLAST of Cysteine dioxygenase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
cdo14.201e-5246.53cysteine dioxygenase type 1 [Source:NCBI gene;Acc:... [more]
cdo17.818e-3536.41cysteine dioxygenase type 1 [Source:NCBI gene;Acc:... [more]
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BLAST of Cysteine dioxygenase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cdo18.110e-4943.48cysteine dioxygenase, type I [Source:NCBI gene;Acc... [more]
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BLAST of Cysteine dioxygenase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cysteine dioxygenase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO403874.319e-4148.09Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cysteine dioxygenase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cdo11.128e-5550.27cysteine dioxygenase type 1 [Source:NCBI gene;Acc:... [more]
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BLAST of Cysteine dioxygenase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000030961.17.574e-15399.51SMESG000030961.1[more]
SMESG000030961.11.154e-14399.48SMESG000030961.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002370 ID=SMED30002370|Name=Cysteine dioxygenase|organism=Schmidtea mediterranea sexual|type=transcript|length=939bp
GTAACTCAATTATTTGACCATATAAATAGATTGTTAATTTTCCAATTTGT
TAATTATAAAAAACTTAATTAATTAATTTATTTAAATTAATAAAATATGA
ACAAATTAACGCTAGGAGAGTTGATCAGTAATATGCACCAGGAATTTGAG
AATCCAAAGCCTGATTTGTATAAAATTCAAAAAATCATGGAGTCGTATTG
TTCAGTTGACGGAGAATGGCAGAAATACGCTTTCGGAGAAAAACAAGAAA
TTGTGTCCACAACAGCATCATATACTCGACATTTAGTTGATTCTGGAAAT
GGTCATTTTAATTTAATGATTCTGGTGTGGAAAAAGAGCCACGGGTCAAG
CATTCATGCTCATAGTAACTCAAACTGTTTAATGAAGTTATTGGAAGGAA
GCCTCAAAGAAAGCAGATACAAATGGCCAAAATCCAAGAACGAGCCAATG
GCACTTCAATCAAAGGTTTACCTAAAGGAGAATGAAGTTTCCTACATTAC
CGATGAAATCGGTCTACATCGAGTTGAAAATCCAAGCCATACTGACATTG
CGGTTTCATTACACTTATATTGGCCCCCATTTGACTGGGCTAGAATTTTC
GACGAGAACACTGGAAAAGATTTTATAACTTCCATGTCATTCCATACGAT
TTACAATGGCCAGGATTCTGTTATTTTGAACACTTCTGTTCCCATTGTCC
CAGACAACAATTAAATCTCACTTCAAATGGACTTCAAAGTTGTTTTTTAT
TTTAGTTTTAAGCCAAAACAGACGTTTCAATAAATGCTGTTTTTTCACCA
GGAGATTTGATGAAGCTAATTTGATATGATCTTTTTTGATATTCCTCAAG
ACCTTTTGGTAACAGGTTTTTTTCGTGATTCGGCTTGGCTTAACAAATTT
ATTCTATCTTTACGCATTCATTTTAAATAACTTTTTCTG
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protein sequence of SMED30002370-orf-1

>SMED30002370-orf-1 ID=SMED30002370-orf-1|Name=SMED30002370-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=206bp
MNKLTLGELISNMHQEFENPKPDLYKIQKIMESYCSVDGEWQKYAFGEKQ
EIVSTTASYTRHLVDSGNGHFNLMILVWKKSHGSSIHAHSNSNCLMKLLE
GSLKESRYKWPKSKNEPMALQSKVYLKENEVSYITDEIGLHRVENPSHTD
IAVSLHLYWPPFDWARIFDENTGKDFITSMSFHTIYNGQDSVILNTSVPI
VPDNN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR014710RmlC-like_jellyroll
IPR010300CDO_1
IPR011051RmlC_Cupin_sf
Vocabulary: molecular function
TermDefinition
GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0005506iron ion binding
GO:0017172cysteine dioxygenase activity
GO:0046872metal ion binding
GO:0051213dioxygenase activity
GO:0016491oxidoreductase activity
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
GO:0042412taurine biosynthetic process
Vocabulary: cellular component
TermDefinition
GO:0005829cytosol
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR014710RmlC-like jelly roll foldGENE3DG3DSA:2.60.120.10coord: 1..198
e-value: 9.9E-66
score: 222.6
IPR010300Cysteine dioxygenase type IPFAMPF05995CDO_Icoord: 5..170
e-value: 5.8E-44
score: 149.4
IPR010300Cysteine dioxygenase type IPANTHERPTHR12918CYSTEINE DIOXYGENASEcoord: 3..187
NoneNo IPR availablePANTHERPTHR12918:SF1CYSTEINE DIOXYGENASE TYPE 1coord: 3..187
IPR011051RmlC-like cupin domain superfamilySUPERFAMILYSSF51182RmlC-like cupinscoord: 5..186