Ig-like domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002350 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 1
Homology
BLAST of Ig-like domain-containing protein vs. Ensembl Human
Match: LRIG2 (leucine rich repeats and immunoglobulin like domains 2 [Source:HGNC Symbol;Acc:HGNC:20889]) HSP 1 Score: 86.6557 bits (213), Expect = 1.390e-16 Identity = 83/350 (23.71%), Postives = 152/350 (43.43%), Query Frame = 3
Query: 540 VAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIE--TNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQ---------------------LNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKC----APRIFTQDRVYEMTKDHNITFTCEFHA---NPGGTVTWSKNGMIVQN----HWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTH 1487
+ E+ +E+ NL+ ++ L L L L ++ N I ++SP+A+ +L L LS NQ+ + S+ + L L L+L +N + + D F+ L L+ L+L + IE + GLT+L L L N ++++ I L++++ L E L + CDC+L+WL W + +++ ++S C P L+ ++I ++ + D C P+I T + N+T TC + +P TV W K+ I+ + ++ R + +++ + L L NV D G ++CI+T H
Sbjct: 265 MEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQL----TRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVS-----------------CAHPEWLAGQSIL-------NVDLKDFVCDDFLKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTV-WRKDSEILYDVDTENFVRYWQQAGEALEYTSILHLFNVNFTDEGKYQCIVTNH 585
BLAST of Ig-like domain-containing protein vs. Ensembl Human
Match: LRIT2 (leucine rich repeat, Ig-like and transmembrane domains 2 [Source:HGNC Symbol;Acc:HGNC:23443]) HSP 1 Score: 82.0333 bits (201), Expect = 2.044e-15 Identity = 89/407 (21.87%), Postives = 161/407 (39.56%), Query Frame = 3
Query: 387 FLWIFIVLD-QVQFGLSVQGCITIMKDSKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNE-------------FYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSK--------NGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKVISPQNI 1541
FL + + LD + GC T ++S + CT+ + +IP ++ ++ IEN L + N+ L L LN N I+ + A H+P+L LRL GN++ S+P ++ L LDL N + +P+ Q L +L LDL++N T +S+ + ++ A Q L +NPW CDC L+ L V++ K ++ + + + +I C+ P + + +F ++ + + P+I T + N+T C A+P ++ W+ +G++ H V + + + L + DSGN+ C+ + + K N L V Q +
Sbjct: 8 FLLVLVFLDTHAAQPFCLPGC-TCSEESFGRTLQCTS--VSLGKIPGNLSEEFKQVRIENSPLFEMPQGSFINMSTLEYLWLNFNNISVIHLGALEHLPELRELRLEGNKLC----SVPWTAFRATPLLRVLDLKRNKIDALPELALQFL-------------------------VSLTYLDLSSNRLTVVSKSVFLNWPAYQKCRQPDCGAEILSSLVVALHDNPWVCDCRLRGL--------VQFVKSITLPVILVNSYLI------CQGPLSKAGQ-LFHETELSACM-------KPQISTPSANITIRAGQNVTLRCLAQASPSPSIAWTYPLSMWREFDGLLGGKHLTPVLTSSTGEDTALSELAIPAAHLVDSGNYTCMASNSIGKSNLVISLHVQPAQAL 360
BLAST of Ig-like domain-containing protein vs. Ensembl Human
Match: NYX (nyctalopin [Source:HGNC Symbol;Acc:HGNC:8082]) HSP 1 Score: 79.337 bits (194), Expect = 9.078e-15 Identity = 56/192 (29.17%), Postives = 87/192 (45.31%), Query Frame = 3
Query: 507 FTRIPE--RFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQ----LNEFYLFNNPWNCDCNLQWLKAWF 1064
F R+P R + +E + + S+ L+ L L +L+L +N++ + AF L L L+ N + +P+ + L++L TL+L N L V +F L +L +L L N ++E L+ L L L N T L+ A Q L +LF NPW CDC L+WL+ W
Sbjct: 171 FRRVPGALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLA----ELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDR-NSIAFVEEGAFQNLSGLLALHLNGNRLTVLA------WVAFQPGFFLGRLFLFRNPWCCDCRLEWLRDWM 351 HSP 2 Score: 58.9214 bits (141), Expect = 2.677e-8 Identity = 48/180 (26.67%), Postives = 79/180 (43.89%), Query Frame = 3
Query: 498 KANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLS--GNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLS----EGL----SISLKAMQLNEFY 1007
+A R+P P + I ++ L + LP+L L+L N ++ ++P AF +P+L LRL+ G+ YL + + L +L LDL+ L VP+ L LR L+ + F L GL NL L ++ +GL S+SL+A ++ +
Sbjct: 50 RAGLLRVPAELPCEAVSIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAA-----LSRLRRLDLAACRLFSVPERLLAELPALR--ELAAFDNLFRRVPGALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVH 222
BLAST of Ig-like domain-containing protein vs. Ensembl Human
Match: NYX (nyctalopin [Source:HGNC Symbol;Acc:HGNC:8082]) HSP 1 Score: 79.337 bits (194), Expect = 9.078e-15 Identity = 56/192 (29.17%), Postives = 87/192 (45.31%), Query Frame = 3
Query: 507 FTRIPE--RFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQ----LNEFYLFNNPWNCDCNLQWLKAWF 1064
F R+P R + +E + + S+ L+ L L +L+L +N++ + AF L L L+ N + +P+ + L++L TL+L N L V +F L +L +L L N ++E L+ L L L N T L+ A Q L +LF NPW CDC L+WL+ W
Sbjct: 171 FRRVPGALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLA----ELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDR-NSIAFVEEGAFQNLSGLLALHLNGNRLTVLA------WVAFQPGFFLGRLFLFRNPWCCDCRLEWLRDWM 351 HSP 2 Score: 58.9214 bits (141), Expect = 2.677e-8 Identity = 48/180 (26.67%), Postives = 79/180 (43.89%), Query Frame = 3
Query: 498 KANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLS--GNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLS----EGL----SISLKAMQLNEFY 1007
+A R+P P + I ++ L + LP+L L+L N ++ ++P AF +P+L LRL+ G+ YL + + L +L LDL+ L VP+ L LR L+ + F L GL NL L ++ +GL S+SL+A ++ +
Sbjct: 50 RAGLLRVPAELPCEAVSIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAA-----LSRLRRLDLAACRLFSVPERLLAELPALR--ELAAFDNLFRRVPGALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVH 222
BLAST of Ig-like domain-containing protein vs. Ensembl Human
Match: LRIG3 (leucine rich repeats and immunoglobulin like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991]) HSP 1 Score: 80.1073 bits (196), Expect = 1.163e-14 Identity = 81/343 (23.62%), Postives = 144/343 (41.98%), Query Frame = 3
Query: 555 IENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIE-TNGLY-------------------------GLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVT--WSKNGMIVQN-HWRRVSWNRSQG---IKFKAWLTLQNVEENDSGNWRCILTTH 1487
+++ NL+ I L L L L L+ N I ++SP+A+ +L L L+ N + + + SS + L L+TL + N + ++ D F+ L L+ L+L + IE NG + GL L+ LDL++N +L +K +Q + +L + CDC L+WL W + + + S C P L R+IF + + D +D P+I Q K N++F C ++ +T W K+ ++ + + R+QG +++ L L+ VE G ++C+++ H
Sbjct: 270 LDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHL----SRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQ--QLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNAS-----------------CAHPQLLKGRSIF--AVSPDGFVCDDFP-KPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNH 586
BLAST of Ig-like domain-containing protein vs. Ensembl Celegans
Match: slt-1 (Slit homolog 1 protein [Source:UniProtKB/Swiss-Prot;Acc:G5EFX6]) HSP 1 Score: 91.6633 bits (226), Expect = 1.540e-18 Identity = 74/229 (32.31%), Postives = 109/229 (47.60%), Query Frame = 3
Query: 543 AEIIIENQNLSVIDSAQL----KNLPN-LVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHT---------------------LDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPK 1151
AE + ++ +S + QL +N+PN + L L N+ITK+ PN F+ + L +L+L NQI N SSL++L+KL LDLSEN + V D Q + L +LNL N F +E N + +L+VL L N TT E + + + L FNNPWNCDC L+W++ W + + + + + G IE LQ K
Sbjct: 19 AECVCVDRTVSCV-GQQLTEVPQNIPNDTIRLDLQDNEITKIGPNDFSSLMNLKALQLMDNQIVTIHN-QSFSSLVFLQKLRLSRNRIRHLPDNVFQNNLKLTHLDLSENDITVVSDAQLQGPEFLEVLNLD-KNHIFCLENNVISSWVSLEVLTLNGNRLTTFEEPSNARFRQLDL-----FNNPWNCDCRLRWMRKWLEKAEGQNKTVCATPLNL-QGSSIEILQDK 238 HSP 2 Score: 53.9138 bits (128), Expect = 6.130e-7 Identity = 46/137 (33.58%), Postives = 72/137 (52.55%), Query Frame = 3
Query: 669 THVPQLIS-LRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISL-KAMQLNEFYLFNNPWNCDCNLQWLKAWFTSH 1073
T +P+ + L LSGN I + +S++ L+ L LDLS N + F+ D F+ L +LR L L+ NK + + L +NL++LDL+ N+ S SI KA ++ E + N CDC + L +W S+
Sbjct: 508 TSIPRFATQLLLSGNNISTVD---LNSNIHVLENLEVLDLSNNHITFINDKSFEKLSKLRELRLND-NKLHHFSSMVLDEQSNLEILDLSGNNIQCFS---SIFFNKATRIREIKVIGNDLLCDCRILPLMSWLRSN 637 HSP 3 Score: 53.5286 bits (127), Expect = 7.974e-7 Identity = 63/227 (27.75%), Postives = 91/227 (40.09%), Query Frame = 3
Query: 501 ANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSER 1181
+ T +P P EI +E +S I S KNL NL L L+ N IT++ P AF + L +L L GN I + S + L L L L+ N L + F + +L +L+L N + ++ + +LT+ L+ +L NP CDCNLQWL IN K IE +CE P L ++
Sbjct: 276 SGLTYVPTNLPPSTTEIRLEQNQISSIPSHSFKNLKNLTRLDLSKNIITEIQPKAFLGLHNLHTLVLYGNNI----TDLKSDTFEGLGSLQLLLLNANQLTCIRRGTFDHVPKLSMLSLY---------DNDIKSISEVTFQNLTS------------------LSTLHLAKNPLICDCNLQWLAQ------------------INLQKNIETSGARCEQPKRLRKK 453
BLAST of Ig-like domain-containing protein vs. Ensembl Celegans
Match: pxn-1 (Peroxidasin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q1ENI8]) HSP 1 Score: 74.3294 bits (181), Expect = 3.183e-13 Identity = 102/454 (22.47%), Postives = 161/454 (35.46%), Query Frame = 3
Query: 387 FLWIFIVLDQVQFGLSVQGCITIMKDSKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIY----LGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDL----SKDITINSGKIIEDLQPKCESPFPLS----------------------ERNIFSDSTNTDSIGIND-------------LKC----------------------APRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKVIS--PQNIID 1547
L + I QF ++ + D K + C++ + TRIP+ V ++I N + + + L+ L L L NKI + N H+P+L L L+ N++ L +S P +SL LK+ H + E L + PD L LD ++N +L L +L A L+ +L +NPW+CDC +KA KVK+ K + ++ + ++D C P S N+ DS++ D I+D + C +P+ + R + + CE NP T+ W NG R +S + Q L + E DSG + C V KV F L +IS P NI +
Sbjct: 5 LLLLVIATSSWQFVAGLECPVECTCDKKGLVVDCSS--SGLTRIPKNISRNVRSLVIRNNRIHKLKRSDLEGFNQLETLVLTHNKIKIIEENVLDHLPELKRLSLAHNELVYIPPLCSDSRPLASL-NLKRNHIQFIDEQVLRYFPD---------------------------------LTQLDFSHNRIQSLRTKLFDNLPA--LSHAHLHSNPWHCDCRASKVKALL--QKVKWEKKVYCTNPVELRHQALDEVDDSALTCARPAEESWTGEEIKLTCAKNSSSKLVVWMYENVEVDSSSLDGYEIHDTVITVPRKTNVNFMTCTYDFDHIPHHRRLRQSQHQGNGSPQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGK------RFISSRKRQLGLSNNVLRIYPFLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYE 412
BLAST of Ig-like domain-containing protein vs. Ensembl Celegans
Match: sma-10 (Leucine-rich repeats and immunoglobulin-like domains protein sma-10 [Source:UniProtKB/Swiss-Prot;Acc:Q965M2]) HSP 1 Score: 68.5514 bits (166), Expect = 1.593e-11 Identity = 77/307 (25.08%), Postives = 127/307 (41.37%), Query Frame = 3
Query: 606 PNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPD----YYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWS--KNG---MIVQNHWRRVSWNRSQGIK--------FKAWLTLQNVEENDSGNWRCI 1475
P L L+L+SN+I L +F + QL L LS N I +S+ +L+ + LH LDLS N L + Y + LR L T N+ I L+ LDLT+N T+ + + ++L + ++ CDC + WL +W Y L K I KC P PL++ ++ + +T ++ ++ +I Q FTC + ++ W +NG ++VQ+ +S NR+ + A L L NV D+ ++C+
Sbjct: 315 PKLKWLSLHSNRIQSLPSGSFRVLRQLEELILSANSI----DSLHKFALVGMSSLHKLDLSSNTLAVCVEDGAVLYNTSMPFLRSLRF-TNNQLRVIPKRAFERFPALEELDLTDNPIATIHPE---AFEPLELKRLVMNSSSILCDCQISWLASWI------YRLKLDKSSII----------AKCSYPPPLAD--LYVVAIDTANLTCHNDSPRAKIVRQPVEVSTLIGEKARFTCNVYGASPLSIEWRVMENGQPRVLVQDSATFLSINRTAVVNGTFDERELAAAELLLDNVAMTDNSEYQCV 595 HSP 2 Score: 51.6026 bits (122), Expect = 2.915e-6 Identity = 46/147 (31.29%), Postives = 73/147 (49.66%), Query Frame = 3
Query: 531 PDQVAEIIIENQNLSV-----IDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQI----YLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNH 944
P A++ IE +L+ I + + LV L L N IT L+ +F+ + +L SL L+ N I +L N +PS L + L+ N + + D F + L+ LNLST N+ + ++GLT+L+VLDL+ N
Sbjct: 165 PTTSAKVNIEKLDLASNSITDIGTDHFSSFNTLVTLKLARNHITTLNQFSFSRLRKLESLDLTRNMIREVRFLAFNQLPS--------LQNVSLARNDVYRLDDGMFYACEGLKHLNLST-NRVQAVTEGWMFGLTSLEVLDLSYNQ 302
BLAST of Ig-like domain-containing protein vs. Ensembl Celegans
Match: sma-10 (Leucine-rich repeats and immunoglobulin-like domains protein sma-10 [Source:UniProtKB/Swiss-Prot;Acc:Q965M2]) HSP 1 Score: 68.5514 bits (166), Expect = 1.593e-11 Identity = 77/307 (25.08%), Postives = 127/307 (41.37%), Query Frame = 3
Query: 606 PNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPD----YYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWS--KNG---MIVQNHWRRVSWNRSQGIK--------FKAWLTLQNVEENDSGNWRCI 1475
P L L+L+SN+I L +F + QL L LS N I +S+ +L+ + LH LDLS N L + Y + LR L T N+ I L+ LDLT+N T+ + + ++L + ++ CDC + WL +W Y L K I KC P PL++ ++ + +T ++ ++ +I Q FTC + ++ W +NG ++VQ+ +S NR+ + A L L NV D+ ++C+
Sbjct: 315 PKLKWLSLHSNRIQSLPSGSFRVLRQLEELILSANSI----DSLHKFALVGMSSLHKLDLSSNTLAVCVEDGAVLYNTSMPFLRSLRF-TNNQLRVIPKRAFERFPALEELDLTDNPIATIHPE---AFEPLELKRLVMNSSSILCDCQISWLASWI------YRLKLDKSSII----------AKCSYPPPLAD--LYVVAIDTANLTCHNDSPRAKIVRQPVEVSTLIGEKARFTCNVYGASPLSIEWRVMENGQPRVLVQDSATFLSINRTAVVNGTFDERELAAAELLLDNVAMTDNSEYQCV 595 HSP 2 Score: 51.6026 bits (122), Expect = 2.915e-6 Identity = 46/147 (31.29%), Postives = 73/147 (49.66%), Query Frame = 3
Query: 531 PDQVAEIIIENQNLSV-----IDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQI----YLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNH 944
P A++ IE +L+ I + + LV L L N IT L+ +F+ + +L SL L+ N I +L N +PS L + L+ N + + D F + L+ LNLST N+ + ++GLT+L+VLDL+ N
Sbjct: 165 PTTSAKVNIEKLDLASNSITDIGTDHFSSFNTLVTLKLARNHITTLNQFSFSRLRKLESLDLTRNMIREVRFLAFNQLPS--------LQNVSLARNDVYRLDDGMFYACEGLKHLNLST-NRVQAVTEGWMFGLTSLEVLDLSYNQ 302
BLAST of Ig-like domain-containing protein vs. Ensembl Celegans
Match: sma-10 (Leucine-rich repeats and immunoglobulin-like domains protein sma-10 [Source:UniProtKB/Swiss-Prot;Acc:Q965M2]) HSP 1 Score: 68.1662 bits (165), Expect = 1.780e-11 Identity = 77/307 (25.08%), Postives = 127/307 (41.37%), Query Frame = 3
Query: 606 PNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPD----YYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWS--KNG---MIVQNHWRRVSWNRSQGIK--------FKAWLTLQNVEENDSGNWRCI 1475
P L L+L+SN+I L +F + QL L LS N I +S+ +L+ + LH LDLS N L + Y + LR L T N+ I L+ LDLT+N T+ + + ++L + ++ CDC + WL +W Y L K I KC P PL++ ++ + +T ++ ++ +I Q FTC + ++ W +NG ++VQ+ +S NR+ + A L L NV D+ ++C+
Sbjct: 315 PKLKWLSLHSNRIQSLPSGSFRVLRQLEELILSANSI----DSLHKFALVGMSSLHKLDLSSNTLAVCVEDGAVLYNTSMPFLRSLRF-TNNQLRVIPKRAFERFPALEELDLTDNPIATIHPE---AFEPLELKRLVMNSSSILCDCQISWLASWI------YRLKLDKSSII----------AKCSYPPPLAD--LYVVAIDTANLTCHNDSPRAKIVRQPVEVSTLIGEKARFTCNVYGASPLSIEWRVMENGQPRVLVQDSATFLSINRTAVVNGTFDERELAAAELLLDNVAMTDNSEYQCV 595 HSP 2 Score: 50.8322 bits (120), Expect = 4.749e-6 Identity = 46/147 (31.29%), Postives = 73/147 (49.66%), Query Frame = 3
Query: 531 PDQVAEIIIENQNLSV-----IDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQI----YLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNH 944
P A++ IE +L+ I + + LV L L N IT L+ +F+ + +L SL L+ N I +L N +PS L + L+ N + + D F + L+ LNLST N+ + ++GLT+L+VLDL+ N
Sbjct: 165 PTTSAKVNIEKLDLASNSITDIGTDHFSSFNTLVTLKLARNHITTLNQFSFSRLRKLESLDLTRNMIREVRFLAFNQLPS--------LQNVSLARNDVYRLDDGMFYACEGLKHLNLST-NRVQAVTEGWMFGLTSLEVLDLSYNQ 302
BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: kek1 (gene:FBgn0015399 transcript:FBtr0346702) HSP 1 Score: 88.1965 bits (217), Expect = 2.018e-17 Identity = 80/335 (23.88%), Postives = 128/335 (38.21%), Query Frame = 3
Query: 546 EIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAM-QLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCE-SPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNR-------SQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKV 1523
++ + N + I+ K L NLV L L+ N + + A H+P L L L+ N I+ + S + LH LDLS ++ T I GL L +L L N LSE L +++ + +L+ L +NPW CDC L+ K W + Y + P C P + +R+ F+D + +++ C P + E N + TC A P + W NG ++ N+ ++ R G + ++ L L N +E DS + C+ A F L V
Sbjct: 151 KLYLRNCKIGEIERETFKGLTNLVELDLSHNLLVTVPSLALGHIPSLRELTLASNHIH----KIESQAFGNTPSLHKLDLSH-------------------CDIQT------ISAQAFGGLQGLTLLRLNGN---KLSELLPKTIETLSRLHGIELHDNPWLCDCRLRDTKLWLMKRNIPYP-----------------VAPVCSGGPERIIDRS-FAD------LHVDEFACRPEMLPISHYVEAAMGENASITCRARAVPAANINWYWNGRLLANNSAFTAYQRIHMLEQVEGGFEKRSKLVLTNAQETDSSEFYCVAENRAGMAEANFTLHV 429
BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: kek1 (gene:FBgn0015399 transcript:FBtr0332210) HSP 1 Score: 88.1965 bits (217), Expect = 2.018e-17 Identity = 80/335 (23.88%), Postives = 128/335 (38.21%), Query Frame = 3
Query: 546 EIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAM-QLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCE-SPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNR-------SQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKV 1523
++ + N + I+ K L NLV L L+ N + + A H+P L L L+ N I+ + S + LH LDLS ++ T I GL L +L L N LSE L +++ + +L+ L +NPW CDC L+ K W + Y + P C P + +R+ F+D + +++ C P + E N + TC A P + W NG ++ N+ ++ R G + ++ L L N +E DS + C+ A F L V
Sbjct: 151 KLYLRNCKIGEIERETFKGLTNLVELDLSHNLLVTVPSLALGHIPSLRELTLASNHIH----KIESQAFGNTPSLHKLDLSH-------------------CDIQT------ISAQAFGGLQGLTLLRLNGN---KLSELLPKTIETLSRLHGIELHDNPWLCDCRLRDTKLWLMKRNIPYP-----------------VAPVCSGGPERIIDRS-FAD------LHVDEFACRPEMLPISHYVEAAMGENASITCRARAVPAANINWYWNGRLLANNSAFTAYQRIHMLEQVEGGFEKRSKLVLTNAQETDSSEFYCVAENRAGMAEANFTLHV 429
BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: kek3 (gene:FBgn0028370 transcript:FBtr0300848) HSP 1 Score: 87.0409 bits (214), Expect = 4.140e-17 Identity = 87/345 (25.22%), Postives = 131/345 (37.97%), Query Frame = 3
Query: 546 EIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGL-TNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTW----------SKNGMIVQNHWRRVSWNRSQG--------IKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKV 1523
++ + +L +I+ + L NLV L L+ N ++ + A HV +L LRLSG NP+ VPD F + QL L LS + +I GL ++L+ L L N + + G SL + L+ L N WNC C+L+ L+AW I + P CESP LS R D + ++D C P+I D + NIT +C P V W S G + R + +QG ++ + LT+ + D+G + C KV A+ L V
Sbjct: 140 KVYLARCHLRLIERHAFRKLINLVELDLSQNLLSAIPSLALYHVSELRELRLSG----------------------------NPILRVPDDAFGHVPQLVKLELSDC-RLSHIAVRAFAGLESSLEWLKLDGNRLSEVRSGTITSLAS--LHGLELARNTWNCSCSLRPLRAWMLQQ-----------------NIPSGIPPTCESPPRLSGRAW-------DKLDVDDFACVPQIVATDTTAHGVEGRNITMSCYVEGVPQPAVKWLLKNRLIANLSAGGDGDSDSEPRTAAA-TQGRKTYVVNMLRNASNLTILTADMQDAGIYTCAAENKAGKVEASVTLAV 428
BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: kek3 (gene:FBgn0028370 transcript:FBtr0080752) HSP 1 Score: 87.0409 bits (214), Expect = 4.140e-17 Identity = 87/345 (25.22%), Postives = 131/345 (37.97%), Query Frame = 3
Query: 546 EIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGL-TNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTW----------SKNGMIVQNHWRRVSWNRSQG--------IKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKV 1523
++ + +L +I+ + L NLV L L+ N ++ + A HV +L LRLSG NP+ VPD F + QL L LS + +I GL ++L+ L L N + + G SL + L+ L N WNC C+L+ L+AW I + P CESP LS R D + ++D C P+I D + NIT +C P V W S G + R + +QG ++ + LT+ + D+G + C KV A+ L V
Sbjct: 140 KVYLARCHLRLIERHAFRKLINLVELDLSQNLLSAIPSLALYHVSELRELRLSG----------------------------NPILRVPDDAFGHVPQLVKLELSDC-RLSHIAVRAFAGLESSLEWLKLDGNRLSEVRSGTITSLAS--LHGLELARNTWNCSCSLRPLRAWMLQQ-----------------NIPSGIPPTCESPPRLSGRAW-------DKLDVDDFACVPQIVATDTTAHGVEGRNITMSCYVEGVPQPAVKWLLKNRLIANLSAGGDGDSDSEPRTAAA-TQGRKTYVVNMLRNASNLTILTADMQDAGIYTCAAENKAGKVEASVTLAV 428
BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: kek2 (gene:FBgn0015400 transcript:FBtr0080252) HSP 1 Score: 81.6481 bits (200), Expect = 2.028e-15 Identity = 86/352 (24.43%), Postives = 142/352 (40.34%), Query Frame = 3
Query: 507 FTRIPERFPDQVAEIIIENQNLSVIDSAQL--KNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQN----------HWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKVI 1526
+ +PE + L V+ S + +L NL + L+ N++ ++ AF + L+ L LS N + ++PS + L L LS NP+ + F+ L L L LS IE G+ NL+ L L N + +G I K+ L+ L +N WNCDC L + W V Y L+++ PKC P L + I S+ L C P + Q E+++ N++ TC A P V W NG ++ N ++ + S + ++ + + NV D+G + C+ + + L+VI
Sbjct: 43 LSNLPEGMDPGTQVLNFSGNALQVLQSERFLRMDLLNLQKIYLSRNQLIRIHEKAFRGLTNLVELDLSENAL----QNVPSETFQDYSSLMRLSLSGNPIRELKTSAFRHLSFLTTLELSNCQVE-RIENEAFVGMDNLEWLRLDGNRIGFI-QGTHILPKS--LHGISLHSNRWNCDCRLLDIHFWL----VNYNTPLAEE-------------PKCMEPARLKGQVI-------KSLQREQLACLPEVSPQSSYTEVSEGRNMSITCLVRAIPEPKVLWLFNGQVMSNDSLMDNLHMYYYIDETIGVSGAEEKRSEIFIYNVGAEDNGTFSCVGQNIAGTTFSNYTLRVI 362
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: lrig3 (leucine-rich repeats and immunoglobulin-like domains 3 [Source:NCBI gene;Acc:564554]) HSP 1 Score: 86.6557 bits (213), Expect = 6.521e-17 Identity = 83/346 (23.99%), Postives = 137/346 (39.60%), Query Frame = 3
Query: 555 IENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIE-TNGLY-------------------------GLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGG--TVTWSKNGMIV-------QNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTH 1487
+E NL+ + L L L L L+ N I+++ P+A+ +L L LS NQ+ + + S + L L L + N + F+ D F+ L L+ L+L + IE NG + GL L+ LDL+NN +L +K +L+E +L + CDC L+W W + L C P L R++FS + D +D P+I Q K +N+TF C ++ T W K+ ++ Q H R + + ++ L L+ VE G ++C+++ H
Sbjct: 143 LEFNNLTEVSKGWLYGLLTLQQLHLSHNSISRIKPDAWEFCQKLAELDLSWNQL----SRLEEGSFVGLSVLEQLHIGNNRISFIADGAFRGLTNLQTLDLKFNEISWTIEDMNGPFSALDNLRKLFLQGNRIRSVTRKSFTGLEMLEQLDLSNNAIMSLQANAFSQMK--KLSELHLNTSSLLCDCQLKWFSLWVAEQ-----------------AFLALLNASCAHPHLLKGRSVFSIA--QDEFVCDDFP-KPQITVQPETQSAIKGNNVTFVCSAASSSDSPMTFAWKKDNELLSEPEIQNQAHVRAAAGETGELTEYTTTLQLRQVEFTSEGRYQCVISNH 462
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: slit2 (slit homolog 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-010306-3]) HSP 1 Score: 83.1889 bits (204), Expect = 1.061e-15 Identity = 67/228 (29.39%), Postives = 102/228 (44.74%), Query Frame = 3
Query: 384 LFLWIFIVLDQVQFGLSVQGCITIMKDSKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAM-QLNEFYLFNNPWNCDCNLQWLKAWF 1064
+F+ +VL + G Q C + S + + + +P P V + + NL+ I A L NL L L NKI+ + AF + +L LRL+ N + + +P + KL LDLSEN + +P F+ +++ L L N+ IE L +L+VL L NN+ + LS S M +L F L +N CDCN+ WL W
Sbjct: 1 MFVLKSVVLCALLCGAGAQSCPSQCSCSGTAVDC---HGQSLRSVPRNIPRNVERLDLNANNLTKITKADFAGLKNLRVLQLMENKISSIERGAFQDLQELERLRLNRNNLQV----LPELLFLGTTKLFRLDLSENQIQGIPRKAFRGSTEIKNLQLDY-NQISCIEDGAFRALRDLEVLTLNNNNISRLS---VASFNHMPKLRTFRLHSNNLLCDCNVAWLSDWL 217 HSP 2 Score: 72.0182 bits (175), Expect = 3.164e-12 Identity = 61/225 (27.11%), Postives = 100/225 (44.44%), Query Frame = 3
Query: 507 FTRIPERFPDQVAEIIIENQNLSVIDSAQL-KNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSE 1178
T+IP+ P AE+ + N +V+++ + K LP L + L++NKIT + F + L L+ N++ SM L L L TL L N +S N G + GL+++++L L +N T++S G +L + L+ L NP+NC+C+L WL W ++ +T N P+C+SP+ L E
Sbjct: 507 LTKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINLSNNKITDIEEGTFEGASGVNELILTSNRLEGVHYSM----LKGLGGLRTLMLRSN-------------------RISCVNNGSFT------GLSSVRLLSLYDNLITSMSPGAFDTLHS--LSTLNLLANPFNCNCHLAWLGEWLRKKRI---------VTGN---------PRCQSPYFLKE 682 HSP 3 Score: 65.4698 bits (158), Expect = 2.925e-10 Identity = 50/193 (25.91%), Postives = 86/193 (44.56%), Query Frame = 3
Query: 504 NFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVK 1082
T IP P+ + EI +E ++ +I + L + L++N+IT+L+ ++F + L SL L GN+I +E P G + L ANK + + L NL +L L +N T+++G SL+A+Q +L NP+ CDC+L+WL + + ++
Sbjct: 281 GLTEIPTNLPETITEIRLEQNSIKIIPAGAFAPYKRLRRIDLSNNQITELASDSFQGLRSLNSLVLYGNKI-----------------------TELPKGLFDGLFSLQLLL------LNANKINCLRVDSFQDLQNLNLLSLYDNKLQTIAKGTFSSLRAIQT--LHLAQNPFMCDCHLKWLADYLQDNPIE 442
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: slit2 (slit homolog 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-010306-3]) HSP 1 Score: 83.1889 bits (204), Expect = 1.086e-15 Identity = 67/228 (29.39%), Postives = 102/228 (44.74%), Query Frame = 3
Query: 384 LFLWIFIVLDQVQFGLSVQGCITIMKDSKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAM-QLNEFYLFNNPWNCDCNLQWLKAWF 1064
+F+ +VL + G Q C + S + + + +P P V + + NL+ I A L NL L L NKI+ + AF + +L LRL+ N + + +P + KL LDLSEN + +P F+ +++ L L N+ IE L +L+VL L NN+ + LS S M +L F L +N CDCN+ WL W
Sbjct: 1 MFVLKSVVLCALLCGAGAQSCPSQCSCSGTAVDC---HGQSLRSVPRNIPRNVERLDLNANNLTKITKADFAGLKNLRVLQLMENKISSIERGAFQDLQELERLRLNRNNLQV----LPELLFLGTTKLFRLDLSENQIQGIPRKAFRGSTEIKNLQLDY-NQISCIEDGAFRALRDLEVLTLNNNNISRLS---VASFNHMPKLRTFRLHSNNLLCDCNVAWLSDWL 217 HSP 2 Score: 71.633 bits (174), Expect = 3.319e-12 Identity = 61/225 (27.11%), Postives = 100/225 (44.44%), Query Frame = 3
Query: 507 FTRIPERFPDQVAEIIIENQNLSVIDSAQL-KNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSE 1178
T+IP+ P AE+ + N +V+++ + K LP L + L++NKIT + F + L L+ N++ SM L L L TL L N +S N G + GL+++++L L +N T++S G +L + L+ L NP+NC+C+L WL W ++ +T N P+C+SP+ L E
Sbjct: 507 LTKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINLSNNKITDIEEGTFEGASGVNELILTSNRLEGVHYSM----LKGLGGLRTLMLRSN-------------------RISCVNNGSFT------GLSSVRLLSLYDNLITSMSPGAFDTLHS--LSTLNLLANPFNCNCHLAWLGEWLRKKRI---------VTGN---------PRCQSPYFLKE 682 HSP 3 Score: 65.4698 bits (158), Expect = 3.145e-10 Identity = 50/193 (25.91%), Postives = 86/193 (44.56%), Query Frame = 3
Query: 504 NFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVK 1082
T IP P+ + EI +E ++ +I + L + L++N+IT+L+ ++F + L SL L GN+I +E P G + L ANK + + L NL +L L +N T+++G SL+A+Q +L NP+ CDC+L+WL + + ++
Sbjct: 281 GLTEIPTNLPETITEIRLEQNSIKIIPAGAFAPYKRLRRIDLSNNQITELASDSFQGLRSLNSLVLYGNKI-----------------------TELPKGLFDGLFSLQLLL------LNANKINCLRVDSFQDLQNLNLLSLYDNKLQTIAKGTFSSLRAIQT--LHLAQNPFMCDCHLKWLADYLQDNPIE 442
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: slit2 (slit homolog 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-010306-3]) HSP 1 Score: 82.8037 bits (203), Expect = 1.276e-15 Identity = 67/228 (29.39%), Postives = 102/228 (44.74%), Query Frame = 3
Query: 384 LFLWIFIVLDQVQFGLSVQGCITIMKDSKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAM-QLNEFYLFNNPWNCDCNLQWLKAWF 1064
+F+ +VL + G Q C + S + + + +P P V + + NL+ I A L NL L L NKI+ + AF + +L LRL+ N + + +P + KL LDLSEN + +P F+ +++ L L N+ IE L +L+VL L NN+ + LS S M +L F L +N CDCN+ WL W
Sbjct: 1 MFVLKSVVLCALLCGAGAQSCPSQCSCSGTAVDC---HGQSLRSVPRNIPRNVERLDLNANNLTKITKADFAGLKNLRVLQLMENKISSIERGAFQDLQELERLRLNRNNLQV----LPELLFLGTTKLFRLDLSENQIQGIPRKAFRGSTEIKNLQLDY-NQISCIEDGAFRALRDLEVLTLNNNNISRLS---VASFNHMPKLRTFRLHSNNLLCDCNVAWLSDWL 217 HSP 2 Score: 71.633 bits (174), Expect = 3.437e-12 Identity = 61/225 (27.11%), Postives = 100/225 (44.44%), Query Frame = 3
Query: 507 FTRIPERFPDQVAEIIIENQNLSVIDSAQL-KNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSE 1178
T+IP+ P AE+ + N +V+++ + K LP L + L++NKIT + F + L L+ N++ SM L L L TL L N +S N G + GL+++++L L +N T++S G +L + L+ L NP+NC+C+L WL W ++ +T N P+C+SP+ L E
Sbjct: 507 LTKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINLSNNKITDIEEGTFEGASGVNELILTSNRLEGVHYSM----LKGLGGLRTLMLRSN-------------------RISCVNNGSFT------GLSSVRLLSLYDNLITSMSPGAFDTLHS--LSTLNLLANPFNCNCHLAWLGEWLRKKRI---------VTGN---------PRCQSPYFLKE 682 HSP 3 Score: 65.4698 bits (158), Expect = 3.260e-10 Identity = 50/193 (25.91%), Postives = 86/193 (44.56%), Query Frame = 3
Query: 504 NFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVK 1082
T IP P+ + EI +E ++ +I + L + L++N+IT+L+ ++F + L SL L GN+I +E P G + L ANK + + L NL +L L +N T+++G SL+A+Q +L NP+ CDC+L+WL + + ++
Sbjct: 281 GLTEIPTNLPETITEIRLEQNSIKIIPAGAFAPYKRLRRIDLSNNQITELASDSFQGLRSLNSLVLYGNKI-----------------------TELPKGLFDGLFSLQLLL------LNANKINCLRVDSFQDLQNLNLLSLYDNKLQTIAKGTFSSLRAIQ--TLHLAQNPFMCDCHLKWLADYLQDNPIE 442
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: slit2 (slit homolog 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-010306-3]) HSP 1 Score: 82.8037 bits (203), Expect = 1.278e-15 Identity = 67/228 (29.39%), Postives = 102/228 (44.74%), Query Frame = 3
Query: 384 LFLWIFIVLDQVQFGLSVQGCITIMKDSKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAM-QLNEFYLFNNPWNCDCNLQWLKAWF 1064
+F+ +VL + G Q C + S + + + +P P V + + NL+ I A L NL L L NKI+ + AF + +L LRL+ N + + +P + KL LDLSEN + +P F+ +++ L L N+ IE L +L+VL L NN+ + LS S M +L F L +N CDCN+ WL W
Sbjct: 1 MFVLKSVVLCALLCGAGAQSCPSQCSCSGTAVDC---HGQSLRSVPRNIPRNVERLDLNANNLTKITKADFAGLKNLRVLQLMENKISSIERGAFQDLQELERLRLNRNNLQV----LPELLFLGTTKLFRLDLSENQIQGIPRKAFRGSTEIKNLQLDY-NQISCIEDGAFRALRDLEVLTLNNNNISRLS---VASFNHMPKLRTFRLHSNNLLCDCNVAWLSDWL 217 HSP 2 Score: 71.633 bits (174), Expect = 3.779e-12 Identity = 61/225 (27.11%), Postives = 100/225 (44.44%), Query Frame = 3
Query: 507 FTRIPERFPDQVAEIIIENQNLSVIDSAQL-KNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSE 1178
T+IP+ P AE+ + N +V+++ + K LP L + L++NKIT + F + L L+ N++ SM L L L TL L N +S N G + GL+++++L L +N T++S G +L + L+ L NP+NC+C+L WL W ++ +T N P+C+SP+ L E
Sbjct: 507 LTKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINLSNNKITDIEEGTFEGASGVNELILTSNRLEGVHYSM----LKGLGGLRTLMLRSN-------------------RISCVNNGSFT------GLSSVRLLSLYDNLITSMSPGAFDTLHS--LSTLNLLANPFNCNCHLAWLGEWLRKKRI---------VTGN---------PRCQSPYFLKE 682 HSP 3 Score: 65.0846 bits (157), Expect = 3.406e-10 Identity = 50/193 (25.91%), Postives = 86/193 (44.56%), Query Frame = 3
Query: 504 NFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVK 1082
T IP P+ + EI +E ++ +I + L + L++N+IT+L+ ++F + L SL L GN+I +E P G + L ANK + + L NL +L L +N T+++G SL+A+Q +L NP+ CDC+L+WL + + ++
Sbjct: 281 GLTEIPTNLPETITEIRLEQNSIKIIPAGAFAPYKRLRRIDLSNNQITELASDSFQGLRSLNSLVLYGNKI-----------------------TELPKGLFDGLFSLQLLL------LNANKINCLRVDSFQDLQNLNLLSLYDNKLQTIAKGTFSSLRAIQT--LHLAQNPFMCDCHLKWLADYLQDNPIE 442
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: NYX (nyctalopin [Source:HGNC Symbol;Acc:HGNC:8082]) HSP 1 Score: 88.5817 bits (218), Expect = 8.407e-18 Identity = 64/197 (32.49%), Postives = 98/197 (49.75%), Query Frame = 3
Query: 495 YKANFTRIPE--RFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKV 1079
++ NF RIP R + + I +E+ + + L++L NL L L NKI + +F +L L L+ N + N +P +S LK L L+L N + V +FQ L +L +L L N+ YIE LT+L L L +N+ TTL + L +LF NPW CDC ++WL+ W ++K+
Sbjct: 143 FQNNFRRIPGAIRGMENLTHIYLESNRIEAVAYNSLQDLINLKYLNLQDNKINVIHDRSFQDCQKLEYLYLNDNLL----NELPENSFKGLKCLKMLNLGGNFIRNVSSAWFQDLVELEVLYLDR-NRISYIEEGAFENLTSLVTLHLNSNNLTTLP--FEVFRPVYFLGRLFLFRNPWECDCRIKWLQDWMDNYKL 332 HSP 2 Score: 52.373 bits (124), Expect = 2.672e-6 Identity = 46/177 (25.99%), Postives = 79/177 (44.63%), Query Frame = 3
Query: 498 KANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRIL--------NLSTANKGF------YIET--------NGLYGLTNLQVLDLTNNHFTTLSE 962
+ IP+ FP + + I ++ N+ + LP L L+L+ N I+ ++P AF +P L L+++ N+ + + + LKKL LDL++ L +PD F L L L + A +G Y+E+ N L L NL+ L+L +N + +
Sbjct: 26 RIGLPEIPKEFPCEASFINLDKNNIKFLYERAFGTLPLLKGLSLSHNNISFITPGAFKGLPNLTELKMAHNEYI---RYLHTRTFSVLKKLVKLDLADCNLFNIPDRIFVELPSLHELIFFQNNFRRIPGAIRGMENLTHIYLESNRIEAVAYNSLQDLINLKYLNLQDNKINVIHD 199
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: LRIG3 (leucine-rich repeats and immunoglobulin like domains 3 [Source:NCBI gene;Acc:100151727]) HSP 1 Score: 79.7221 bits (195), Expect = 8.361e-15 Identity = 85/325 (26.15%), Postives = 142/325 (43.69%), Query Frame = 3
Query: 555 IENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIE-TNGLY-GLTNLQVL------DLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGG--TVTWSK-NGMIVQNHWRRVSWNRSQG---IKFKAWLTLQNVEENDSGNWRCILTTH 1487
+++ L+ I L L L L L+ N I+ ++P+A+ +L L L+ NQ+ + SS L L L + N + F+ D F+ L L L+L + + IE NG + GL L+ L DL++N T++ +K++Q + YL CDC L+WL W K + + S C P L ++IF+ S D +D P+I Q K N+TF C ++ T W K N ++ + + R+QG +++ L L+NVE + G ++C+++ H
Sbjct: 242 LDHNRLTEITKGWLYGLLMLQKLHLSQNAISSITPDAWEFCQKLSELDLAFNQL----TRLEESSFAGLGLLGGLYIGNNKINFIADGAFRGLSSLNSLDLKSNEISWTIEDMNGTFSGLERLKRLCPYLCRDLSDNAITSMQTNAFSQMKSLQ--QLYLNTTSLLCDCQLKWLPKWLAESKFQTFVNAS-----------------CGHPQILKGKSIFAVS--PDDFVCDDFP-KPQITVQPETQSAIKGSNVTFICSAASSSESPMTFAWKKDNELLHDSEIENYAHLRAQGGEVMEYTTILRLRNVEFINEGKYQCVISNH 540
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: slit1 (slit guidance ligand 1 [Source:NCBI gene;Acc:100036682]) HSP 1 Score: 80.4925 bits (197), Expect = 1.009e-14 Identity = 68/260 (26.15%), Postives = 116/260 (44.62%), Query Frame = 3
Query: 486 CTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQL-KNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESP-----FPLSERNIFSDSTNTDSIGINDLKCAPR 1247
C+N K T+IP+R P AE+ + N ++ +++ L + LP+L + L++NKI+++ AF + L L+ N + + M F+ L+ LR L L N+ + + GL N+++L L +N +T++ G +L++ L+ L NP+NC+C L WL W K+ +T N P+C++P PL + F D D G +L CAP+
Sbjct: 430 CSNLK--LTKIPDRIPQSTAELRLNNNEIATLEATGLFRKLPHLKKINLSNNKISEIEDAAFEGAASVSELHLTANHLESVRSGM----------------------------FRGLEGLRTLMLRN-NRVSCVHNDSFTGLRNVRLLSLYDNQISTITPGAFDTLQS--LSTLNLLANPFNCNCQLAWLGDWLRKRKI---------VTGN---------PRCQNPDFLRQIPLQDV-AFPDFRCED--GQEELSCAPQ 635 HSP 2 Score: 64.3142 bits (155), Expect = 1.031e-9 Identity = 61/276 (22.10%), Postives = 112/276 (40.58%), Query Frame = 3
Query: 477 MSICTN-----YKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPK---CESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMT 1280
M C+N T IP P+ + EI +E + + L + L++N+I++++P+AF + L SL L GN+I ++ P G + L L ++ I + L NL +L L +N +L++G +L+A+Q +L NP+ CDCNL+WL + ++ ++ + + K I ++ K C P +E + N+D + C P+ + V + +
Sbjct: 193 MCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSVPPGAFSPYKKLRRIDLSNNQISEIAPDAFQGLRSLNSLVLYGNKI-----------------------TDLPKGVFSGLHALQLLLLNANKINC------IRADTFQDLQNLSLLSLYDNKIQSLAKGTFAALRAIQ--TLHLAQNPFICDCNLKWLADFLRTNPIETSGARCASPRRLANKRIGQIKSKKFRCSGKMPGTEDYQLNSECNSDVV------CPPKCRCESNVVDCS 431 HSP 3 Score: 60.4622 bits (145), Expect = 1.327e-8 Identity = 46/143 (32.17%), Postives = 70/143 (48.95%), Query Frame = 3
Query: 636 NKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWF 1064
N+I+ + AF + +L LRL+ NQ++ ++P + L LDLSEN + +P F+ +L+ L L N+ IE L L+VL L NN+ T + +S +L F L +N CDC+L WL W
Sbjct: 3 NQISNVERGAFDDMKELERLRLNRNQLH----TLPELLFQNNQALSRLDLSENLIQAIPRKTFRGATELKNLQLDK-NQISCIEDGAFRALRGLEVLTLNNNNITAIP--VSSFNHMPKLRTFRLHSNNLFCDCHLAWLSQWL 138
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: slit1 (slit guidance ligand 1 [Source:NCBI gene;Acc:100036682]) HSP 1 Score: 80.4925 bits (197), Expect = 1.109e-14 Identity = 68/260 (26.15%), Postives = 116/260 (44.62%), Query Frame = 3
Query: 486 CTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQL-KNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESP-----FPLSERNIFSDSTNTDSIGINDLKCAPR 1247
C+N K T+IP+R P AE+ + N ++ +++ L + LP+L + L++NKI+++ AF + L L+ N + + M F+ L+ LR L L N+ + + GL N+++L L +N +T++ G +L++ L+ L NP+NC+C L WL W K+ +T N P+C++P PL + F D D G +L CAP+
Sbjct: 508 CSNLK--LTKIPDRIPQSTAELRLNNNEIATLEATGLFRKLPHLKKINLSNNKISEIEDAAFEGAASVSELHLTANHLESVRSGM----------------------------FRGLEGLRTLMLRN-NRVSCVHNDSFTGLRNVRLLSLYDNQISTITPGAFDTLQS--LSTLNLLANPFNCNCQLAWLGDWLRKRKI---------VTGN---------PRCQNPDFLRQIPLQDV-AFPDFRCED--GQEELSCAPQ 713 HSP 2 Score: 70.0922 bits (170), Expect = 1.386e-11 Identity = 54/183 (29.51%), Postives = 85/183 (46.45%), Query Frame = 3
Query: 516 IPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWF 1064
+P+ P + + N++ I+ L L L L N+I+ + AF + +L LRL+ NQ++ ++P + L LDLSEN + +P F+ +L+ L L N+ IE L L+VL L NN+ T + +S +L F L +N CDC+L WL W
Sbjct: 41 VPKNIPRSTERLELYGNNITRINKNDFSGLKQLRVLQLMENQISNVERGAFDDMKELERLRLNRNQLH----TLPELLFQNNQALSRLDLSENLIQAIPRKTFRGATELKNLQLDK-NQISCIEDGAFRALRGLEVLTLNNNNITAIP--VSSFNHMPKLRTFRLHSNNLFCDCHLAWLSQWL 216 HSP 3 Score: 64.3142 bits (155), Expect = 1.001e-9 Identity = 61/276 (22.10%), Postives = 112/276 (40.58%), Query Frame = 3
Query: 477 MSICTN-----YKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPK---CESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMT 1280
M C+N T IP P+ + EI +E + + L + L++N+I++++P+AF + L SL L GN+I ++ P G + L L ++ I + L NL +L L +N +L++G +L+A+Q +L NP+ CDCNL+WL + ++ ++ + + K I ++ K C P +E + N+D + C P+ + V + +
Sbjct: 271 MCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSVPPGAFSPYKKLRRIDLSNNQISEIAPDAFQGLRSLNSLVLYGNKI-----------------------TDLPKGVFSGLHALQLLLLNANKINC------IRADTFQDLQNLSLLSLYDNKIQSLAKGTFAALRAIQ--TLHLAQNPFICDCNLKWLADFLRTNPIETSGARCASPRRLANKRIGQIKSKKFRCSGKMPGTEDYQLNSECNSDVV------CPPKCRCESNVVDCS 509
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: slit1 (slit guidance ligand 1 [Source:NCBI gene;Acc:100036682]) HSP 1 Score: 80.4925 bits (197), Expect = 1.111e-14 Identity = 68/260 (26.15%), Postives = 116/260 (44.62%), Query Frame = 3
Query: 486 CTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQL-KNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESP-----FPLSERNIFSDSTNTDSIGINDLKCAPR 1247
C+N K T+IP+R P AE+ + N ++ +++ L + LP+L + L++NKI+++ AF + L L+ N + + M F+ L+ LR L L N+ + + GL N+++L L +N +T++ G +L++ L+ L NP+NC+C L WL W K+ +T N P+C++P PL + F D D G +L CAP+
Sbjct: 520 CSNLK--LTKIPDRIPQSTAELRLNNNEIATLEATGLFRKLPHLKKINLSNNKISEIEDAAFEGAASVSELHLTANHLESVRSGM----------------------------FRGLEGLRTLMLRN-NRVSCVHNDSFTGLRNVRLLSLYDNQISTITPGAFDTLQS--LSTLNLLANPFNCNCQLAWLGDWLRKRKI---------VTGN---------PRCQNPDFLRQIPLQDV-AFPDFRCED--GQEELSCAPQ 725 HSP 2 Score: 70.4774 bits (171), Expect = 1.162e-11 Identity = 54/183 (29.51%), Postives = 85/183 (46.45%), Query Frame = 3
Query: 516 IPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWF 1064
+P+ P + + N++ I+ L L L L N+I+ + AF + +L LRL+ NQ++ ++P + L LDLSEN + +P F+ +L+ L L N+ IE L L+VL L NN+ T + +S +L F L +N CDC+L WL W
Sbjct: 53 VPKNIPRSTERLELYGNNITRINKNDFSGLKQLRVLQLMENQISNVERGAFDDMKELERLRLNRNQLH----TLPELLFQNNQALSRLDLSENLIQAIPRKTFRGATELKNLQLDK-NQISCIEDGAFRALRGLEVLTLNNNNITAIP--VSSFNHMPKLRTFRLHSNNLFCDCHLAWLSQWL 228 HSP 3 Score: 64.3142 bits (155), Expect = 9.445e-10 Identity = 61/276 (22.10%), Postives = 112/276 (40.58%), Query Frame = 3
Query: 477 MSICTN-----YKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPK---CESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMT 1280
M C+N T IP P+ + EI +E + + L + L++N+I++++P+AF + L SL L GN+I ++ P G + L L ++ I + L NL +L L +N +L++G +L+A+Q +L NP+ CDCNL+WL + ++ ++ + + K I ++ K C P +E + N+D + C P+ + V + +
Sbjct: 283 MCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSVPPGAFSPYKKLRRIDLSNNQISEIAPDAFQGLRSLNSLVLYGNKI-----------------------TDLPKGVFSGLHALQLLLLNANKINC------IRADTFQDLQNLSLLSLYDNKIQSLAKGTFAALRAIQ--TLHLAQNPFICDCNLKWLADFLRTNPIETSGARCASPRRLANKRIGQIKSKKFRCSGKMPGTEDYQLNSECNSDVV------CPPKCRCESNVVDCS 521
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Lrit2 (leucine-rich repeat, immunoglobulin-like and transmembrane domains 2 [Source:MGI Symbol;Acc:MGI:2444885]) HSP 1 Score: 82.8037 bits (203), Expect = 6.483e-16 Identity = 85/359 (23.68%), Postives = 144/359 (40.11%), Query Frame = 3
Query: 504 NFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNE-------------FYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKVISPQNI 1541
+ +IP+ FP+++ ++ IEN L + N+ +L L LN N +T + A +P+L LRL GN++ S+P ++ L LDL N + VP+ Q LTNL LD+++N T +S+G+ ++ A Q + L NNPW CDC L+ L + S + I +NS + + P+S+ T +G+ P I T + N+T C A+P T+ W K + + ++ ++GI L + + D GN+ C+ + + + LL V Q +
Sbjct: 45 SLGKIPDNFPEELKQVRIENSPLFELSQGFFTNMSSLEYLWLNFNNVTVIHLGALEDLPELRELRLEGNKL----RSVPWTAFRATPLLRVLDLKHNRIDSVPELALQF-------------------------LTNLIYLDISSNRLTVVSKGVFLNWPAYQKRQQLGCGAEFLSNMVLSLHNNPWLCDCRLRGLAQFVKSVGPPF-------ILVNSYLVCQG---------PVSKAGQLLHETE---LGVC---MKPTISTPSVNVTIQVGKNVTLQCFAQASPSPTIAW-KYPLSTWREFDVLASPIAEGIILSQ-LVIPAAQLVDGGNYTCMAFNSIGRSSLVILLYVQPAQAM 350
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Lrig2 (leucine-rich repeats and immunoglobulin-like domains 2 [Source:MGI Symbol;Acc:MGI:2443718]) HSP 1 Score: 82.8037 bits (203), Expect = 1.460e-15 Identity = 84/355 (23.66%), Postives = 148/355 (41.69%), Query Frame = 3
Query: 540 VAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIE--------------------------TNGLYGLTNLQVLDLTNNHFTTLSEGL--SISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKC----APRIFTQDRVYEMTKDHNITFTCEFHA---NPGGTVTWSKNGMIVQN----HWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTH 1487
+ E+ +E+ NL+ ++ L L L L ++ N I K+SP+A+ +L L LS NQ+ + S+ + L L L+L +N + + D F+ L L+ L+L + + IE GL +L+ LDL NN ++ E LK + LN L CDC+L+WL W + ++ ++S C P L+ ++I ++ + D C P+I T + N+T TC + +P T+ W K+ I+ + ++ R + +++ + L L +V D G ++CI+T H
Sbjct: 264 MEELELEHNNLTGVNKGWLYGLRMLQQLYMSQNAIEKISPDAWEFCQRLSELDLSYNQL----TRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNDISWAIEDASEAFSGLKSLTKLILQGNRIKSVTQKAFIGLESLEYLDLNNNAIMSIQENAFSQTHLKGLVLNTSSLL-----CDCHLKWLLQWLVDNNFHHSVNVS-----------------CAHPEWLAGQSIL-------NVDLKDFVCDDFLKPQIRTHPESTIALRGVNVTLTCTAVSSSDSPMSTI-WRKDSEILYDVDIENFVRYRQQDGEALEYTSVLRLFSVNFTDEGKYQCIVTNH 584
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Lrig2 (leucine-rich repeats and immunoglobulin-like domains 2 [Source:MGI Symbol;Acc:MGI:2443718]) HSP 1 Score: 82.4185 bits (202), Expect = 1.571e-15 Identity = 84/355 (23.66%), Postives = 148/355 (41.69%), Query Frame = 3
Query: 540 VAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIE--------------------------TNGLYGLTNLQVLDLTNNHFTTLSEGL--SISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKC----APRIFTQDRVYEMTKDHNITFTCEFHA---NPGGTVTWSKNGMIVQN----HWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTH 1487
+ E+ +E+ NL+ ++ L L L L ++ N I K+SP+A+ +L L LS NQ+ + S+ + L L L+L +N + + D F+ L L+ L+L + + IE GL +L+ LDL NN ++ E LK + LN L CDC+L+WL W + ++ ++S C P L+ ++I ++ + D C P+I T + N+T TC + +P T+ W K+ I+ + ++ R + +++ + L L +V D G ++CI+T H
Sbjct: 264 MEELELEHNNLTGVNKGWLYGLRMLQQLYMSQNAIEKISPDAWEFCQRLSELDLSYNQL----TRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNDISWAIEDASEAFSGLKSLTKLILQGNRIKSVTQKAFIGLESLEYLDLNNNAIMSIQENAFSQTHLKGLVLNTSSLL-----CDCHLKWLLQWLVDNNFHHSVNVS-----------------CAHPEWLAGQSIL-------NVDLKDFVCDDFLKPQIRTHPESTIALRGVNVTLTCTAVSSSDSPMSTI-WRKDSEILYDVDIENFVRYRQQDGEALEYTSVLRLFSVNFTDEGKYQCIVTNH 584
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Nyx (nyctalopin [Source:MGI Symbol;Acc:MGI:2448607]) HSP 1 Score: 78.1814 bits (191), Expect = 1.709e-14 Identity = 54/194 (27.84%), Postives = 84/194 (43.30%), Query Frame = 3
Query: 489 TNYKANFTRIPE--RFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWF 1064
T + F R+P R + E + + S L + L +L+L +N++ + AF L L ++P+++ L++L TL+L N LG V +F L +L +L L N ++E L+ L L L N T LS + L +LF NPW CDC L+WL+ W
Sbjct: 160 TAFDNLFRRVPGALRGLANLTHAHFERSRIEAVASGSLLGMRRLRSLSLQANRVRAVHAGAFGDCGALEDL----LLNDNLLATLPAAAFRGLRRLRTLNLGGNALGSVARAWFSDLAELELLYLDR-NSITFVEEGAFQNLSGLLALHLNGNRLTVLS--WAAFQPGFFLGRLFLFRNPWRCDCQLEWLRDWM 346 HSP 2 Score: 66.6254 bits (161), Expect = 6.806e-11 Identity = 44/166 (26.51%), Postives = 76/166 (45.78%), Query Frame = 3
Query: 498 KANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGE-NSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQ 992
+A R+P+ FP + A I ++ L ++ LP+L L+L N ++ ++P AF +P+L LRL+ N GE + + L +L LDL+ L VP+ L LR L+ + F L GL NL + ++ G + ++ ++
Sbjct: 45 RAGLQRVPQEFPCEAASIDLDRNGLRILGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHN----GELRYLHVRTFAALGRLRRLDLAACRLFSVPERLLAELPALR--ELTAFDNLFRRVPGALRGLANLTHAHFERSRIEAVASGSLLGMRRLR 204
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Slit1 (slit guidance ligand 1 [Source:MGI Symbol;Acc:MGI:1315203]) HSP 1 Score: 79.337 bits (194), Expect = 1.770e-14 Identity = 56/199 (28.14%), Postives = 94/199 (47.24%), Query Frame = 3
Query: 486 CTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQL-KNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKV 1079
C++ K ++IPER P E+ + N +S++++ L K L +L + L++NK++++ F + L L+ NQ+ + M F+ L LR L L N+ I + GL N+++L L +NH TT+S G +L+A L+ L NP+NC+C+L WL W K+
Sbjct: 526 CSSLK--LSKIPERIPQSTTELRLNNNEISILEATGLFKKLSHLKKINLSNNKVSEIEDGTFEGAASVSELHLTANQLESIRSGM----------------------------FRGLDGLRTLMLRN-NRISCIHNDSFTGLRNVRLLSLYDNHITTISPGAFDTLQA--LSTLNLLANPFNCNCHLSWLGDWLRKRKI 691 HSP 2 Score: 70.8626 bits (172), Expect = 7.639e-12 Identity = 58/190 (30.53%), Postives = 83/190 (43.68%), Query Frame = 3
Query: 495 YKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWF 1064
+ IP+ P + + N++ I L L L L N+I + AF + +L LRL+ NQ+ + +P + L LDLSEN L VP F+ L+ L L N+ IE L L+VL L NN+ TT+ +S +L F L +N CDC+L WL W
Sbjct: 48 HGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLQV----LPELLFQNNQALSRLDLSENFLQAVPRKAFRGATDLKNLQLDK-NRISCIEEGAFRALRGLEVLTLNNNNITTIP--VSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWL 230 HSP 3 Score: 65.4698 bits (158), Expect = 2.992e-10 Identity = 62/234 (26.50%), Postives = 97/234 (41.45%), Query Frame = 3
Query: 420 QFGLSVQG------CITIMKDSKYKMSICTN-----YKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYT 1088
+F S QG T+ S M C++ T IP P+ + EI +E + I L + L++N+I +++P+AF + L SL L GN+I DL G + L L ANK I + L NL +L L +N +L++G SL+A+Q +L NP+ CDCNL+WL + ++ ++ T
Sbjct: 260 EFSCSGQGEAAGAPACTLSSGSCPAMCSCSSGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKI--------------------TDLPRGVFGGL---------YTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQT--LHLAQNPFICDCNLKWLADFLRTNPIETT 462
BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Match: sp|G5EFX6|SLIT1_CAEEL (Slit homolog 1 protein OS=Caenorhabditis elegans OX=6239 GN=slt-1 PE=1 SV=1) HSP 1 Score: 91.6633 bits (226), Expect = 1.958e-17 Identity = 74/229 (32.31%), Postives = 109/229 (47.60%), Query Frame = 3
Query: 543 AEIIIENQNLSVIDSAQL----KNLPN-LVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHT---------------------LDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPK 1151
AE + ++ +S + QL +N+PN + L L N+ITK+ PN F+ + L +L+L NQI N SSL++L+KL LDLSEN + V D Q + L +LNL N F +E N + +L+VL L N TT E + + + L FNNPWNCDC L+W++ W + + + + + G IE LQ K
Sbjct: 19 AECVCVDRTVSCV-GQQLTEVPQNIPNDTIRLDLQDNEITKIGPNDFSSLMNLKALQLMDNQIVTIHN-QSFSSLVFLQKLRLSRNRIRHLPDNVFQNNLKLTHLDLSENDITVVSDAQLQGPEFLEVLNLD-KNHIFCLENNVISSWVSLEVLTLNGNRLTTFEEPSNARFRQLDL-----FNNPWNCDCRLRWMRKWLEKAEGQNKTVCATPLNL-QGSSIEILQDK 238 HSP 2 Score: 53.9138 bits (128), Expect = 7.798e-6 Identity = 46/137 (33.58%), Postives = 72/137 (52.55%), Query Frame = 3
Query: 669 THVPQLIS-LRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISL-KAMQLNEFYLFNNPWNCDCNLQWLKAWFTSH 1073
T +P+ + L LSGN I + +S++ L+ L LDLS N + F+ D F+ L +LR L L+ NK + + L +NL++LDL+ N+ S SI KA ++ E + N CDC + L +W S+
Sbjct: 508 TSIPRFATQLLLSGNNISTVD---LNSNIHVLENLEVLDLSNNHITFINDKSFEKLSKLRELRLND-NKLHHFSSMVLDEQSNLEILDLSGNNIQCFS---SIFFNKATRIREIKVIGNDLLCDCRILPLMSWLRSN 637
BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Match: sp|O94898|LRIG2_HUMAN (Leucine-rich repeats and immunoglobulin-like domains protein 2 OS=Homo sapiens OX=9606 GN=LRIG2 PE=2 SV=3) HSP 1 Score: 86.6557 bits (213), Expect = 6.675e-16 Identity = 83/350 (23.71%), Postives = 152/350 (43.43%), Query Frame = 3
Query: 540 VAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIE--TNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQ---------------------LNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKC----APRIFTQDRVYEMTKDHNITFTCEFHA---NPGGTVTWSKNGMIVQN----HWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTH 1487
+ E+ +E+ NL+ ++ L L L L ++ N I ++SP+A+ +L L LS NQ+ + S+ + L L L+L +N + + D F+ L L+ L+L + IE + GLT+L L L N ++++ I L++++ L E L + CDC+L+WL W + +++ ++S C P L+ ++I ++ + D C P+I T + N+T TC + +P TV W K+ I+ + ++ R + +++ + L L NV D G ++CI+T H
Sbjct: 265 MEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQL----TRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVS-----------------CAHPEWLAGQSIL-------NVDLKDFVCDDFLKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTV-WRKDSEILYDVDTENFVRYWQQAGEALEYTSILHLFNVNFTDEGKYQCIVTNH 585
BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6PFC5|LRIT2_MOUSE (Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2 OS=Mus musculus OX=10090 GN=Lrit2 PE=2 SV=1) HSP 1 Score: 82.8037 bits (203), Expect = 4.535e-15 Identity = 85/359 (23.68%), Postives = 144/359 (40.11%), Query Frame = 3
Query: 504 NFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNE-------------FYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKVISPQNI 1541
+ +IP+ FP+++ ++ IEN L + N+ +L L LN N +T + A +P+L LRL GN++ S+P ++ L LDL N + VP+ Q LTNL LD+++N T +S+G+ ++ A Q + L NNPW CDC L+ L + S + I +NS + + P+S+ T +G+ P I T + N+T C A+P T+ W K + + ++ ++GI L + + D GN+ C+ + + + LL V Q +
Sbjct: 45 SLGKIPDNFPEELKQVRIENSPLFELSQGFFTNMSSLEYLWLNFNNVTVIHLGALEDLPELRELRLEGNKL----RSVPWTAFRATPLLRVLDLKHNRIDSVPELALQF-------------------------LTNLIYLDISSNRLTVVSKGVFLNWPAYQKRQQLGCGAEFLSNMVLSLHNNPWLCDCRLRGLAQFVKSVGPPF-------ILVNSYLVCQG---------PVSKAGQLLHETE---LGVC---MKPTISTPSVNVTIQVGKNVTLQCFAQASPSPTIAW-KYPLSTWREFDVLASPIAEGIILSQ-LVIPAAQLVDGGNYTCMAFNSIGRSSLVILLYVQPAQAM 350
BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Match: sp|Q52KR2|LRIG2_MOUSE (Leucine-rich repeats and immunoglobulin-like domains protein 2 OS=Mus musculus OX=10090 GN=Lrig2 PE=1 SV=1) HSP 1 Score: 82.8037 bits (203), Expect = 1.021e-14 Identity = 84/355 (23.66%), Postives = 148/355 (41.69%), Query Frame = 3
Query: 540 VAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIE--------------------------TNGLYGLTNLQVLDLTNNHFTTLSEGL--SISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKC----APRIFTQDRVYEMTKDHNITFTCEFHA---NPGGTVTWSKNGMIVQN----HWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTH 1487
+ E+ +E+ NL+ ++ L L L L ++ N I K+SP+A+ +L L LS NQ+ + S+ + L L L+L +N + + D F+ L L+ L+L + + IE GL +L+ LDL NN ++ E LK + LN L CDC+L+WL W + ++ ++S C P L+ ++I ++ + D C P+I T + N+T TC + +P T+ W K+ I+ + ++ R + +++ + L L +V D G ++CI+T H
Sbjct: 264 MEELELEHNNLTGVNKGWLYGLRMLQQLYMSQNAIEKISPDAWEFCQRLSELDLSYNQL----TRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNDISWAIEDASEAFSGLKSLTKLILQGNRIKSVTQKAFIGLESLEYLDLNNNAIMSIQENAFSQTHLKGLVLNTSSLL-----CDCHLKWLLQWLVDNNFHHSVNVS-----------------CAHPEWLAGQSIL-------NVDLKDFVCDDFLKPQIRTHPESTIALRGVNVTLTCTAVSSSDSPMSTI-WRKDSEILYDVDIENFVRYRQQDGEALEYTSVLRLFSVNFTDEGKYQCIVTNH 584
BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9GZU5|NYX_HUMAN (Nyctalopin OS=Homo sapiens OX=9606 GN=NYX PE=1 SV=1) HSP 1 Score: 79.337 bits (194), Expect = 4.360e-14 Identity = 56/192 (29.17%), Postives = 87/192 (45.31%), Query Frame = 3
Query: 507 FTRIPE--RFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQ----LNEFYLFNNPWNCDCNLQWLKAWF 1064
F R+P R + +E + + S+ L+ L L +L+L +N++ + AF L L L+ N + +P+ + L++L TL+L N L V +F L +L +L L N ++E L+ L L L N T L+ A Q L +LF NPW CDC L+WL+ W
Sbjct: 171 FRRVPGALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLA----ELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDR-NSIAFVEEGAFQNLSGLLALHLNGNRLTVLA------WVAFQPGFFLGRLFLFRNPWCCDCRLEWLRDWM 351 HSP 2 Score: 58.9214 bits (141), Expect = 1.286e-7 Identity = 48/180 (26.67%), Postives = 79/180 (43.89%), Query Frame = 3
Query: 498 KANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLS--GNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLS----EGL----SISLKAMQLNEFY 1007
+A R+P P + I ++ L + LP+L L+L N ++ ++P AF +P+L LRL+ G+ YL + + L +L LDL+ L VP+ L LR L+ + F L GL NL L ++ +GL S+SL+A ++ +
Sbjct: 50 RAGLLRVPAELPCEAVSIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAA-----LSRLRRLDLAACRLFSVPERLLAELPALR--ELAAFDNLFRRVPGALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVH 222
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A504Z776 (Leucine-rich repeat-containing protein 4 OS=Fasciola gigantica OX=46835 GN=FGIG_10709 PE=4 SV=1) HSP 1 Score: 268.47 bits (685), Expect = 8.306e-74 Identity = 146/401 (36.41%), Postives = 219/401 (54.61%), Query Frame = 3
Query: 390 LWIFIVLDQVQFGLSVQGCITIMKDSKYKM--SICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLL-KQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWF--TSHKVKYTKDLSKDITIN----------------SGKIIEDLQPKCESPFPLSERNIFSDST--NTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKV 1523
+I IV+ V+GC+T + Y M SIC +F IP P QV ++ + +Q++S ++++Q ++LPNL L L+SNKI ++ PN F + L +L L N + G NS L L +L+L +NP+G+VP F L LR+L LS ++ F ++ L GLT LQVLDL+ NH TL E ++ MQL E YL+ NPW CDCNL+WLK WF + K+ Y++ + + + N SG LQP+C SP+ L R +FS T + D C P+ T ++ ++ K N T TCEF A+P G V W +NG ++Q W R+S +++ G F+A LT+++V+ D+G + C L T +VN TF ++V
Sbjct: 46 FYILIVISLPTPATPVRGCVTYVAGEDYSMRQSICDKPDTHFLTIPASLPSQVVKLTVNHQDISELNASQFRHLPNLTYLDLDSNKIIRIHPNTFHVLKHLRTLSLRFNLLTFGVNSFHPDVPHGLIYLESLNLLQNPMGYVPKRIFAPLGSSLRVLVLSGGSEDFQLDPGALDGLTMLQVLDLSYNHLETLHESFETTISHMQLKELYLYGNPWRCDCNLRWLKVWFLKVNTKLIYSRPVPEGVNRNLLDPSAQRWYDYNYGGSGDAPSLLQPRCASPYALFGRPLFSHQTLSGIQPVRTTDFHCLPQALTPNQPIQIMKGSNATITCEFFADPTGIVVWYRNGTLIQQRWERMSTHQTTGRTFQAELTIRDVQSIDAGTYVCFLDTGQGRVNTTFSVQV 446
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A183A877 (Ig-like domain-containing protein OS=Echinostoma caproni OX=27848 PE=4 SV=1) HSP 1 Score: 268.47 bits (685), Expect = 1.724e-73 Identity = 150/413 (36.32%), Postives = 224/413 (54.24%), Query Frame = 3
Query: 384 LFLWIFIVLDQVQFGLSVQGCITIMKDSKYKM--SICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLL-KQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSH--KVKYTKDLSKDITIN----------------SGKIIEDLQPKCESPFPLSERNIFSDST--NTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKVISPQNIIDFK 1553
L+L I I L + F SV+GC+T + Y M SIC +FT IP P QV ++ + +Q+++ ++S Q K+LPNL L L+SNKI ++ PN F + L +L L N + +S L L L+L +NP+G+VP F + LR L LS ++ F ++ L GLT LQ+LDL+ NH +L E +L MQL E YL+ NPW CDCNL+WLK WF + K+ Y++ + + + N +G LQP+C SP+ L R +FS T + D C P+ T ++ ++T N T TCEF A+P G V W +NG ++Q W R+S +++ G F+A LT+Q+V+ +D+G + C L T +VN TF ++V S + K
Sbjct: 85 LYLLIVITLPKAAF--SVRGCVTYVAGEDYSMRQSICDKPDTHFTTIPAALPSQVVKLTVNHQDITELNSTQFKHLPNLTYLDLDSNKIVRIHPNTFHVLKHLQTLSLRFNLLIFSVDSFHPDVTHGLIGLENLNLLQNPMGYVPKRIFAPIGSSLRSLVLSGGSEDFQLDPGALDGLTMLQLLDLSYNHLESLPESFESTLHHMQLKELYLYGNPWRCDCNLRWLKVWFLKYNSKLIYSRPVPEGVNRNLLDPSAQRWYDYNYDGTGDGPSLLQPRCASPYALFGRPLFSHQTLAGLQPVRTTDFHCLPQALTANQPVQLTLGSNATLTCEFFADPTGIVVWYRNGTLIQQRWARMSMHQTTGRTFQAELTVQDVQPSDAGTYVCFLDTGHGRVNTTFSVQVNSDDQTVSSK 495
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A3P8EXC8 (Ig-like domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS3162 PE=4 SV=1) HSP 1 Score: 268.47 bits (685), Expect = 2.083e-73 Identity = 150/413 (36.32%), Postives = 224/413 (54.24%), Query Frame = 3
Query: 384 LFLWIFIVLDQVQFGLSVQGCITIMKDSKYKM--SICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLL-KQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSH--KVKYTKDLSKDITIN----------------SGKIIEDLQPKCESPFPLSERNIFSDST--NTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKVISPQNIIDFK 1553
L+L I I L + F SV+GC+T + Y M SIC +FT IP P QV ++ + +Q+++ ++S Q K+LPNL L L+SNKI ++ PN F + L +L L N + +S L L L+L +NP+G+VP F + LR L LS ++ F ++ L GLT LQ+LDL+ NH +L E +L MQL E YL+ NPW CDCNL+WLK WF + K+ Y++ + + + N +G LQP+C SP+ L R +FS T + D C P+ T ++ ++T N T TCEF A+P G V W +NG ++Q W R+S +++ G F+A LT+Q+V+ +D+G + C L T +VN TF ++V S + K
Sbjct: 85 LYLLIVITLPKAAF--SVRGCVTYVAGEDYSMRQSICDKPDTHFTTIPAALPSQVVKLTVNHQDITELNSTQFKHLPNLTYLDLDSNKIVRIHPNTFHVLKHLQTLSLRFNLLIFSVDSFHPDVTHGLIGLENLNLLQNPMGYVPKRIFAPIGSSLRSLVLSGGSEDFQLDPGALDGLTMLQLLDLSYNHLESLPESFESTLHHMQLKELYLYGNPWRCDCNLRWLKVWFLKYNSKLIYSRPVPEGVNRNLLDPSAQRWYDYNYDGTGDGPSLLQPRCASPYALFGRPLFSHQTLAGLQPVRTTDFHCLPQALTANQPVQLTLGSNATLTCEFFADPTGIVVWYRNGTLIQQRWARMSMHQTTGRTFQAELTVQDVQPSDAGTYVCFLDTGHGRVNTTFSVQVNSDDQTVSSK 495
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A2H1CPY5 (Immunoglobulin I-set domain protein OS=Fasciola hepatica OX=6192 GN=D915_002068 PE=4 SV=1) HSP 1 Score: 266.159 bits (679), Expect = 6.133e-73 Identity = 145/401 (36.16%), Postives = 218/401 (54.36%), Query Frame = 3
Query: 390 LWIFIVLDQVQFGLSVQGCITIMKDSKYKM--SICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLL-KQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWF--TSHKVKYTKDLSKDITIN----------------SGKIIEDLQPKCESPFPLSERNIFSDST--NTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKV 1523
+I IV+ V+GC+T + Y M SIC +F IP P QV ++ + +Q++S ++++Q ++LPNL L L+SNKI ++ PN F + L L L N + G NS L L +L+L +NP+G+VP F L LR+L LS ++ F ++ L GLT LQVLDL+ NH TL E ++ MQL E YL+ NPW CDCNL+WLK WF + K+ Y++ + + + N +G LQP+C SP+ L R +FS T + D C P+ T ++ ++ K N T TCEF A+P G V W +NG ++Q W R+S +++ G F+A LT+++V+ D+G + C L T +VN TF ++V
Sbjct: 46 FYILIVISLPTPATPVRGCVTYVAGEDYSMRQSICDKPDTHFLTIPASLPSQVVKLTVNHQDISELNASQFRHLPNLTYLDLDSNKIIRIHPNTFHVLKHLRILSLRFNLLTFGVNSFHPDVPHGLIYLESLNLLQNPMGYVPKRIFAPLGSSLRVLVLSGGSEDFQLDPGALEGLTMLQVLDLSYNHLETLHESFETTIHHMQLKELYLYGNPWRCDCNLRWLKVWFLKVNTKLIYSRPVPEGVNRNLLDPSAQRWYDYNYGGNGDAPSLLQPRCASPYALFGRPLFSHQTLSGLQPVRTTDFHCLPQALTPNQPIQIMKGSNATITCEFFADPTGIVVWYRNGTLIQQRWERMSMHQTTGRTFQAELTIKDVQSIDAGTYVCFLDTGHGRVNTTFSVQV 446
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A5J4NST5 (Ig-like domain-containing protein OS=Paragonimus westermani OX=34504 GN=DEA37_0010867 PE=4 SV=1) HSP 1 Score: 263.462 bits (672), Expect = 6.461e-73 Identity = 157/433 (36.26%), Postives = 245/433 (56.58%), Query Frame = 3
Query: 474 KMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQ-LRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYT------KDLSKDI------------TINSGKIIEDLQPKCESPFPLSERNIFS--DSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKVISPQ----NI-----------IDFKSILKYXXXXXXXXXXXXXXXXXXXYCVYGFQIQNNRR 1664
+ SIC +F IP P QV ++ I +Q +S+++++Q +LPNL L L+SNK++ + P+ F + +L +L L N + S +++ L +L TL+L +NP+G+VP F + LR L L+ A++ F ++ + L LT LQ LDL++NH TL E ISL +MQLNE YL++NPW CDC+L+WLK WF H K T + +S+ + +I+ LQPKC +P+ +S + +FS S+ + D CAP T + ++ N T +CEF A+P G V W +NG VQNHW R+S ++SQG F + LT+QN++ D+GN+ C L T +VN+TF + + + + NI ++ +LKY GI A L++LL++IG++IYC YG + +R
Sbjct: 2 RQSICDKPDTHFKSIPSALPSQVVKLTINHQEISLLNASQFNHLPNLSYLDLDSNKLSIIRPDTFGRLRKLRTLSLRFNLLSFSIESFHPNAISSLAQLETLNLLQNPIGYVPKQLFAPMGSTLRSLVLAGASEDFELDRDALTNLTVLQTLDLSSNHLETLPEDFEISLNSMQLNELYLYDNPWRCDCHLRWLKVWFLKHNTKMTFSKPVPEGISRKLLEPSMQMWSSPNSIDVDDATAILQPKCATPYAVSGKPLFSSHSSSGLQPVRTTDFHCAPNALTLSQPLHFSRGSNATLSCEFFADPTGIVVWYRNGTRVQNHWSRMSTHQSQGRNFYSELTIQNIQLEDAGNYVCFLDTGHGRVNSTFTVHIETEEHSFANIMSGSMFHWMSGLNANLVLKYTGITASCLVILLMLIGLLIYCFYGRNLCGKKR 434
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: lrig3 (leucine rich repeats and immunoglobulin like domains 3 [Source:NCBI gene;Acc:103037077]) HSP 1 Score: 83.5741 bits (205), Expect = 6.108e-16 Identity = 84/346 (24.28%), Postives = 138/346 (39.88%), Query Frame = 3
Query: 555 IENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIE-TNGLY-------------------------GLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVT--WSKNGMIV-------QNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTH 1487
+E NL+ + L L L L L N I+++ P+A+ +L L L+ NQ+ + S + L L L + N + F+ D F+ L L L+L + IE NG + GL L+ LDL+NN ++ +G + S + +L E L + CDC L+W W H + + S C P L +++F+ S D +D P+I Q K N+TF C ++ +T W K+ ++ Q H R SQ ++ L L +VE + G ++C+++ H
Sbjct: 255 LEYNNLTEVSKGWLYGLLTLQQLHLAHNAISRIKPDAWEFCQKLAELDLNSNQLA----RLEEGSFMGLSVLEQLSIGHNRVSFIADGAFRGLSLLNTLDLKYNEISWTIEDMNGPFSALNNLRKLFLQGNRIRSVTKKSFTGLDLLEQLDLSNNAIMSI-QGNAFS-QMKKLEELLLNTSSLLCDCQLKWFPQWVAEHAFQPLVNAS-----------------CAHPQLLKAKSVFAVS--QDEFVCDDFP-KPQITVQPETQSAIKGTNVTFVCSAASSSDSPMTFAWKKDNEVLNDAEIHNQAHLRSQDGEVSQVTEYTTTLQLHHVESSSEGKYQCVISNH 574
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: nyx (nyctalopin [Source:ZFIN;Acc:ZDB-GENE-061026-3]) HSP 1 Score: 80.1073 bits (196), Expect = 2.611e-15 Identity = 57/197 (28.93%), Postives = 95/197 (48.22%), Query Frame = 3
Query: 495 YKANFTRIPE--RFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKV 1079
+ NF R+P R + + + +E + + L L NL L L N+I+ + ++F + +L + L+ N + + +P S L +L L+L N L + +F L +L +L L N+ I+ LT+L L L +N+ TTL ++ + YLF NPW C+C L+WLK W S+K+
Sbjct: 150 FHNNFRRVPVAIRGMENLTHVYLERNKIEAVAYNSLLGLSNLKYLNLQENRISVIHDDSFKDLHRLENFYLNDNLL----SELPQQSFKGLSRLKMLNLGGNLLTNISKSWFGDLMELEVLYLDR-NRLISIDMGAFENLTSLMTLHLNSNNLTTLP--FAVFQPIYFIGRLYLFRNPWECNCELEWLKEWMESYKL 339 HSP 2 Score: 61.2326 bits (147), Expect = 2.885e-9 Identity = 58/199 (29.15%), Postives = 98/199 (49.25%), Query Frame = 3
Query: 498 KANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQI--YLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYF--QL-LKQLRILN-----LSTANKGF------YIET--------NGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAM-QLNEFYLFNN 1019
+AN +P FP + + + ++ +L + LP+L L+L+ N I+ ++P AF +P L+ L+++ N+ YL + S LK+L LDLS+ L +PD F Q+ LK+L + + A +G Y+E N L GL+NL+ L+L N + + + S K + +L FYL +N
Sbjct: 33 RANMAELPSEFPCEASSLNLDKNSLKFLAERAFGTLPSLKTLSLDHNNISFITPGAFKGLPNLLELKMAHNEYIRYLHTRTFTS-----LKRLVRLDLSDCNLFSMPDRIFVEQISLKELFCFHNNFRRVPVAIRGMENLTHVYLERNKIEAVAYNSLLGLSNLKYLNLQENRISVIHDD---SFKDLHRLENFYLNDN 223
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: lrrc4bb (leucine rich repeat containing 4Bb [Source:ZFIN;Acc:ZDB-GENE-091116-44]) HSP 1 Score: 79.337 bits (194), Expect = 7.551e-15 Identity = 96/407 (23.59%), Postives = 155/407 (38.08%), Query Frame = 3
Query: 483 ICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQV----------------------LDLTNNHFTTLSEGLSISL-------------------------------KAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKC-APRIFTQDRVYEMTKDHNIT--FTCEFHANPGGTVT---W-SKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKV 1523
ICT + +P+ + ++ ++ +I S K+L +L L L+ N I ++ AF +P LI+L L N++ L +PS + YL KL L L NP+ +P Y F + LR L+L K +I GL NL+ L+L+ N +++ L +SL QL +L +NPW C+C++ WL W L + + NS +C +P P ++ D + D C AP I E D N+T E G ++T W + NG ++ + +V + + L NV D+G + C++T AT +L V
Sbjct: 53 ICT--RKGLDEVPQSISVNTRYLNLQENSIQLIKSDTFKHLSHLEILQLSKNHIRQIEVGAFNGLPNLITLELFDNRLPL----VPSQAFEYLSKLRELWLRNNPIETLPAYAFHRVPSLRRLDLGELRKLSFISEAAFEGLVNLRFLNLGMCGLKDVPNLTPLVRLEELELSGNQLGLVAQSLPLSLIERNAFDDLKNLEELNLSHNSLHSLPHDLFTPLQQLERVHLNHNPWVCNCDVLWLSWW-----------LKETVPDNSTCCA-----RCHAP-PGTKGRYIGD------LDQRDFTCYAPVIV------EPPTDLNVTEGMAAELKCRTGTSMTSVNWLTPNGTLMTHGAYKVRIS----VLHDGTLNFTNVTMQDTGPYTCMVTNSAGNTTATAVLNV 420
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: lrrc4.2 (leucine rich repeat containing 4.2 [Source:ZFIN;Acc:ZDB-GENE-030131-7997]) HSP 1 Score: 78.5666 bits (192), Expect = 1.421e-14 Identity = 100/436 (22.94%), Postives = 156/436 (35.78%), Query Frame = 3
Query: 438 QGCITIMKDS-KYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDL----------------------TNNHFTTLSEGLSISLKA-------------MQLNEF---------------------------------YLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKC-APRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTW-SKNGMIV---QNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKV 1523
Q C + S ++ +CT + + R+P P + + ++ +I + ++L +L L L N I K+ AF + L +L L N++ + +PS + YL KL L L NP+ +P Y F + L L+L K YI GL NL+ L+L + N+F + G LK+ M+ N F +L +NPW CDC++ WL W L + I NS +C +P L R + T +C AP I R ++ + C P +V W NG ++ NH R N L NV +D+G + C++T NA+ L V
Sbjct: 38 QNCPAVCSCSNQFSKVVCT--RRSLVRVPSGIPANTRHLNLMENSIEIIQADTFRHLHHLEVLQLGRNSIRKIEVGAFNGLTNLNTLELFDNRLTV----IPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLYNLKYLNLGMCNLREMPVLSPLVGLEELEMSENYFPEIKPGSFRGLKSLKKLWIMNSRITTMERNAFDDVTALVELNLAHNNLSSLPHDLFAPLSYLVELHLHHNPWRCDCDVVWLAWW-----------LREYIPTNS-----TCCGRCHTPAHLRGRYLVEVDQTT-------FQCSAPFILDAPRDLNISAERVAELKCR--TAPMSSVRWLLPNGTVLTHGSNHPRIYVLNDGT-------LNFSNVLASDTGVYTCMVTNMAGNSNASAYLNV 435
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: lrrc4bb (leucine rich repeat containing 4Bb [Source:ZFIN;Acc:ZDB-GENE-091116-44]) HSP 1 Score: 78.1814 bits (191), Expect = 2.212e-14 Identity = 96/407 (23.59%), Postives = 155/407 (38.08%), Query Frame = 3
Query: 483 ICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTN----------------------LQVLDLTNNHFTTLSEGLSISL-------------------------------KAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKC-APRIFTQDRVYEMTKDHNIT--FTCEFHANPGGTVT---W-SKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKV 1523
ICT + +P+ + ++ ++ +I S K+L +L L L+ N I ++ AF +P LI+L L N++ L +PS + YL KL L L NP+ +P Y F + LR L+L K +I GL N L+ L+L+ N +++ L +SL QL +L +NPW C+C++ WL W L + + NS +C +P P ++ D + D C AP I E D N+T E G ++T W + NG ++ + +V + + L NV D+G + C++T AT +L V
Sbjct: 53 ICT--RKGLDEVPQSISVNTRYLNLQENSIQLIKSDTFKHLSHLEILQLSKNHIRQIEVGAFNGLPNLITLELFDNRLPL----VPSQAFEYLSKLRELWLRNNPIETLPAYAFHRVPSLRRLDLGELRKLSFISEAAFEGLVNLRFLNLGMCGLKDVPNLTPLVRLEELELSGNQLGLVAQSLPLSLIERNAFDDLKNLEELNLSHNSLHSLPHDLFTPLQQLERVHLNHNPWVCNCDVLWLSWW-----------LKETVPDNSTCCA-----RCHAP-PGTKGRYIGD------LDQRDFTCYAPVIV------EPPTDLNVTEGMAAELKCRTGTSMTSVNWLTPNGTLMTHGAYKVRIS----VLHDGTLNFTNVTMQDTGPYTCMVTNSAGNTTATAVLNV 420
BLAST of Ig-like domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000079.1 (pep scaffold:Pmarinus_7.0:GL476403:206014:206980:-1 gene:ENSPMAG00000000071.1 transcript:ENSPMAT00000000079.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 87.4261 bits (215), Expect = 2.282e-19 Identity = 60/194 (30.93%), Postives = 88/194 (45.36%), Query Frame = 3
Query: 495 YKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITK--LSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTS 1070
Y P P + E+ ++ N+ V+ A L+ P L L LN N ++ + P F P+L L LS N + +P + L L L +N + +PD F L L L L N+ + YGL LQ +DL+ N +LS+G L++ L+ NNPW+CDC L WL+ W S
Sbjct: 71 YDNQLEEFPAHLPPNLRELHLQENNIEVVPGAVLERTPFLEKLHLNDNSVSSAGIEPATFHGTPRLKLLFLSRNHLSSVPRGLP-------RGLEELRLDDNRISRIPDRIFGQLTYLSRLALDD-NQISRLPPGVFYGLKQLQRIDLSGNGLRSLSQGSFNGLES--LSHLSACNNPWHCDCGLTWLRNWLRS 254
BLAST of Ig-like domain-containing protein vs. Ensembl Sea Lamprey
Match: LINGO2 (leucine rich repeat and Ig domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21207]) HSP 1 Score: 85.1149 bits (209), Expect = 2.497e-17 Identity = 93/359 (25.91%), Postives = 144/359 (40.11%), Query Frame = 3
Query: 546 EIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIY--LGENS------------------MPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKC-APRIFTQDRVYEMT--KDHNITFTCEFHANPGGTVTWSKNGMIVQNHWR-RVSWNRSQG---IKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKV--ISPQ 1535
E+ +E NL+ + + L L L +L L I + P+AF +P+L SL + + LG S +P +L L L TLDLS N + V F L +LR L + +E L G+ L +L+L+ N TL EG S +++ L NP CDC L W+ A + G + +P C++P +S F+D G L C PRI + R ++T + + C +P V W W+ RV+ RS G + L ++ + +D G + C+ + +A LL V +SPQ
Sbjct: 198 ELALERCNLTAVPTEALAQLHGLSSLRLRHLGIAAVKPHAFQRLPRLRSLEIDHWPLLETLGAGSFSSLNLTSLSVTNTNITRVPRLALQTLVHLRTLDLSFNAIASVEAGAFATLTRLRELRMERTGL-LVVEPRALQGVEQLGLLNLSGNGLRTLEEGALDSPGLLEV--LRLDGNPLACDCRLLWVVA----------------LNRRGGLSFDGREPSCDAPESVSGAE-FADLPEPLPKGY--LACRRPRI-SPRRTQQLTAVEGQAVHLMCRADGDPAPDVAWLAP-------WKQRVTPRRSTGRLAVLHDGTLLIRRAQVSDGGPYVCVASNAGDNDSARTLLSVRGLSPQ 526 HSP 2 Score: 61.2326 bits (147), Expect = 6.993e-10 Identity = 52/196 (26.53%), Postives = 85/196 (43.37%), Query Frame = 3
Query: 369 ICLQDLFLWIFIVLDQVQFGLSVQGCITIMKDSKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTL 956
+C Q L I +VL ++ S GC D + ++ IPE P + + + L + + + L L LN N I + P AF +P L +L + GN+I L +P L L LD+SEN + + D+ F+ L++L L + N+ Y+ + GL L+ L L + T +
Sbjct: 22 VCSQVLLALITVVLPVLES--SAMGC-PARCDCSAPLRSVVCHRRKLVSIPEGIPTETRLLDLSKNRLRALSAGDFASHGQLEELQLNENVIAGVEPGAFGGLPHLRALGMRGNRIKL----IPPGVFAGLGNLTRLDVSENKIVVLLDFAFRDLRRLLELRVGD-NELVYVTRHAFAGLAALRELALERCNLTAV 209
BLAST of Ig-like domain-containing protein vs. Ensembl Sea Lamprey
Match: lrig3 (leucine-rich repeats and immunoglobulin-like domains 3 [Source:NCBI gene;Acc:564554]) HSP 1 Score: 78.9518 bits (193), Expect = 1.943e-15 Identity = 81/326 (24.85%), Postives = 137/326 (42.02%), Query Frame = 3
Query: 528 FPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVT--WSKNGMIVQN----HWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTH 1487
F ++ E+ + + +LS I+ L L +L L N ++ ++ AF + L++L L+GN+I M + L+ L+ L LSEN + S A K F GL L LDL+NN ++ +G SLKA L E L ++ CDC L+WL W + T ++ C P L R+IF S DS + D P+I Q + N+TF C ++ +T W K+ ++ + ++ +V + ++ L L +V+ G ++C+++ H
Sbjct: 182 FCQKLDELDLSHNHLSRIEEGTFVGLGMLRSLLLAHNHLSNIADGAFKELRSLLTLDLAGNEISWTIEDM-HGAFTGLENLNKLVLSENKIK------------------SIAKKAFI-------GLERLHSLDLSNNALMSIQDGSFSSLKA--LTEMRLNSSSLLCDCTLKWLSPWLEERGFRDT-----------------VEADCAHPEWLKGRDIF--SVEPDSY-VCDTFPKPQISVQPETTMALRSSNVTFVCSARSSSDSPITFSWKKDNEVISDGHVENYAQVREREEEVTEYTTRLHLISVDFKHEGRYQCVISNH 459 HSP 2 Score: 49.6766 bits (117), Expect = 2.517e-6 Identity = 37/109 (33.94%), Postives = 60/109 (55.05%), Query Frame = 3
Query: 630 NSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTL 956
N N+IT L+P F +P L L L+ N+I + S S L+ L +L L N +G + D F L++L IL+L N + LYGL++LQ L++++N+ + +
Sbjct: 73 NKNRITSLAPKLFK-LPHLQHLELTRNRI----KRIESLSFFGLESLQSLRLQRNNIGRLMDGAFWRLEKLEILHLDF-NALTNVTKGWLYGLSSLQQLNMSHNNVSRI 175 HSP 3 Score: 47.7506 bits (112), Expect = 9.271e-6 Identity = 42/144 (29.17%), Postives = 67/144 (46.53%), Query Frame = 3
Query: 561 NQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQ 992
N+N + +L LP+L +L L N+I ++ +F + L SLRL N I + + L+KL L L N L V + L L+ LN+S N I+ + L LDL++NH + + EG + L ++
Sbjct: 73 NKNRITSLAPKLFKLPHLQHLELTRNRIKRIESLSFFGLESLQSLRLQRNNI----GRLMDGAFWRLEKLEILHLDFNALTNVTKGWLYGLSSLQQLNMSHNNVS-RIDLDAWEFCQKLDELDLSHNHLSRIEEGTFVGLGMLR 211
BLAST of Ig-like domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000078.1 (pep scaffold:Pmarinus_7.0:GL476403:206014:206980:-1 gene:ENSPMAG00000000071.1 transcript:ENSPMAT00000000078.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 76.6406 bits (187), Expect = 1.964e-15 Identity = 68/237 (28.69%), Postives = 96/237 (40.51%), Query Frame = 3
Query: 495 YKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITK------------------LSPNAFTHVPQ-----LISLRLSGNQI----------------------YLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTS 1070
Y P P + E+ ++ N+ V+ A L+ P L L LN N ++ LS N + VP+ L LRL N+I LG+ S+ +SS L L L L+ N L VP + L Q IL N+ + YGL LQ +DL+ N +LS+G L++ L+ NNPW+CDC L WL+ W S
Sbjct: 71 YDNQLEEFPAHLPPNLRELHLQENNIEVVPGAVLERTPFLEKLHLNDNSVSSAGIEPATFHGTPRLKLLFLSRNHLSSVPRGLPRGLEELRLDDNRISRIPDRIFGQLTYLSRLALDGNILGDASISASSFSGLPSLTELSLARNVLTTVPTHLPMLGLQKLILQ---DNQISRLPPGVFYGLKQLQRIDLSGNGLRSLSQGSFNGLES--LSHLSACNNPWHCDCGLTWLRNWLRS 302
BLAST of Ig-like domain-containing protein vs. Ensembl Sea Lamprey
Match: islr2 (immunoglobulin superfamily containing leucine-rich repeat 2 [Source:ZFIN;Acc:ZDB-GENE-050320-95]) HSP 1 Score: 78.1814 bits (191), Expect = 4.615e-15 Identity = 74/257 (28.79%), Postives = 117/257 (45.53%), Query Frame = 3
Query: 597 KNLP-NLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKG--FYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKC-AP--RIFTQDRVYE--MTKDHNITFTCEFHANPGGTVTW 1343
K LP N+ +L+L++N++ LS +AF +P + SL LS N++ S+ +L L +L LDLS N L D+ ++ L+ L L + N + + LT+L+ L L +N F T+ EG +L A L+ L+ NP C C +WL AW + I I S + I C P L + + + D++C AP R+ + V E + D + C+ P TV+W
Sbjct: 50 KGLPANITSLSLSANRLRSLSRDAFEEIPLMSSLWLSHNELV----SIEKGTLAGLVQLRNLDLSNNQLA---DFSWEDLRNLTALQVLKLNNNNLVRLPRDAFETLTDLRSLRLHHNLFATIEEGTFENLHA--LSHLLLYENPLRCSCKARWLPAWLN----------TTSIDIPSKENI-----ACAEPDELKGQAVQQ---------MPDVECVAPTVRLSSSPDVRETRLYSDFAVVLDCQADGLPAPTVSW 273
BLAST of Ig-like domain-containing protein vs. Ensembl Nematostella
Match: EDO48179 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK32]) HSP 1 Score: 63.1586 bits (152), Expect = 3.774e-10 Identity = 70/316 (22.15%), Postives = 128/316 (40.51%), Query Frame = 3
Query: 588 AQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYY---FQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAM-QLNEFYLFNNPWNCDCNLQWLKAWFTSH-KVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRR-------------VSWNRSQGIKFKAWLTLQNVEENDSGNWRCILT 1481
A ++ P L L L N+++ + F H+ L L L+ N+IY + S L+ L LDLS N + + + F+ L L L L N+ I GL N++ L+L+ N T++ E S + M +L + +L + CDC ++W +W S ++T ++ +C P L +++F + D+ + P+I + + N+T C +N V+ WR V + + + + L L +V+ +D+G ++CI +
Sbjct: 340 ADWRSFPVLRKLNLERNRLSHIQDTTFKHLLALKVLNLANNRIY----HISQGSFSDLRSLEGLDLSNNDISWTVEEMNGPFRGLTNLASLRLD-GNRITAIAATAFLGLENIKYLNLSANIITSIQEN---SFQGMDKLQKLWLNTSQLMCDCKIKWFGSWLRSRPSTRHT-----------------VRARCLHPQTLYMKSVF--NITPDAFVCDTSNPIPQISVHPPSQKAMRGDNVTLRCRVQV-------VQRNSSSVRLQWRLGYEVISERDITDFVRTDDDDIVTYNSDLFLISVDFSDAGLYQCIAS 621 HSP 2 Score: 52.7582 bits (125), Expect = 6.316e-7 Identity = 59/197 (29.95%), Postives = 85/197 (43.15%), Query Frame = 3
Query: 486 CTNYKANFTRIP--ERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQL------ISLRLSGNQIY--------LGEN---SMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNN 1019
C + N IP + FP + + + + + I S L NL LNSNKI+ + +AFT++ L LR + Y LG+N S+PS +L L+ L LDLS N + F L L +L LS N+ I +G LQ L L N+FT + L+ +Q YL +N
Sbjct: 137 CHLHHNNIRGIPPWDSFPSTLMTLTLHHNKIVAIPSLNTTKQHALRNLYLNSNKISSIGHHAFTNLSNLQNLYSIAYLRYTSLTEYKKEDCIKKLGKNRLTSVPSDALSQLQSLKRLDLSRNFFTSILASAFNRLSSLEVLKLS-KNRISTIR-GAFWGQNKLQQLYLDRNNFTAIQTSSFFGLRDLQ--NLYLQSN 329
BLAST of Ig-like domain-containing protein vs. Ensembl Nematostella
Match: EDO43258 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZD5]) HSP 1 Score: 57.3806 bits (137), Expect = 2.428e-8 Identity = 42/139 (30.22%), Postives = 74/139 (53.24%), Query Frame = 3
Query: 447 ITIMKDSKYKMSICTNYKANFTRIPERFPDQ-------VAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQL 842
+T++ D +S + NF RI + P + E+ ++ +L+V+ LK L L +L LN N+I+K+ NAF + L+ L L GN++ S+P+S++ L +L L+L NP+ + D+ F+ L +L
Sbjct: 48 LTVVPDGLKALSRLQHLNLNFNRI-SKVPRNAFNKLRLLVELFLDYNDLTVVPDG-LKALSRLQHLNLNFNRISKVPRNAFNKLRLLVELNLRGNKL----KSIPTSAINDLMRLQQLELDGNPIRVIKDHAFKGLFRL 180 HSP 2 Score: 49.2914 bits (116), Expect = 7.480e-6 Identity = 38/123 (30.89%), Postives = 66/123 (53.66%), Query Frame = 3
Query: 492 NYKANFTRIPERFPDQVA----EII--IENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQL 842
++ AN +I +R PD E++ + NQ S+ + L+ + L +LTL N+IT+++ N F V L +L L+ NQI + ++ + ++L TLDLSEN +P Q +++L
Sbjct: 252 DFNANMNKI-KRIPDMSGCKSMELLKLVHNQISSI--GSSLQGMARLKDLTLEGNRITEVNDNTFKGVKSLETLDLAKNQI----KHISKNAFSHFERLQTLDLSENLFVRLPSAGMQQIRRL 367
BLAST of Ig-like domain-containing protein vs. Ensembl Nematostella
Match: EDO27257 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T9R6]) HSP 1 Score: 53.5286 bits (127), Expect = 4.070e-8 Identity = 47/162 (29.01%), Postives = 72/162 (44.44%), Query Frame = 3
Query: 579 IDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWF 1064
I+ L NL L +++ + K++ F + L L +S N+I SL L L L ++ N L VP + + +K L+ L+LS AN Y+ + + LQ L L NN + E LK ++ +L NP+ CDC L AW
Sbjct: 1 IEEGAFNGLDNLRKLHVSATGMKKITQGTFGSLMSLEFLDVSFNEI----RHFDEESLACLPLLEVLHINNNSLTTVPLHALRKVKFLKELDLS-ANLISYVSSTAFANNSKLQKLLLHNNTIRLIHEDAFSQLKGLR--ALFLRGNPFQCDCQLNGFHAWL 155
BLAST of Ig-like domain-containing protein vs. Ensembl Nematostella
Match: EDO31669 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXA1]) HSP 1 Score: 55.0694 bits (131), Expect = 1.067e-7 Identity = 67/285 (23.51%), Postives = 115/285 (40.35%), Query Frame = 3
Query: 555 IENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDL--------------TNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKD-HNITFTCEFHANPGGTVTWSKNGMIV 1364
+ + I+ +NL L +L L+ NK+ +L+ F + L L L N++ SM S LK L L L N + + + F LK L L L +N+ I + L GLTN++ + + N T + + + + + N +CDCN W + W SH YT+D++ C++P L + + + N +D+KC P + T ++ ++ ++ C + N G TW+ NG V
Sbjct: 126 LRRNGIKEIEFGAFRNLTALESLILSKNKLRRLTYAMFDTLSYLRLLSLVDNRLTGLTRSMFSG----LKSLRELYLQRNQIQDIEPWTFTSLKSLASLYLD-SNQLTVISRDTLLGLTNVKDIHVYFNKLRYVARDAFKPNPQLTRIVWDVPALFRRTRPEFANMVGNMLHCDCNALWFRDWLISH--AYTRDVT-----------------CQTPPRL--KGVLLGNLND-----SDIKCDPVVVTVSPKKKLVREWESVELYC--NVNTGAVYTWTVNGSAV 377
BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: lrig3 (leucine rich repeats and immunoglobulin like domains 3 [Source:NCBI gene;Acc:101155735]) HSP 1 Score: 85.5001 bits (210), Expect = 1.421e-16 Identity = 88/360 (24.44%), Postives = 141/360 (39.17%), Query Frame = 3
Query: 534 DQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIE-TNGLY-------------------------GLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCA----PRIFTQDRVYEMTKDHNITFTCEFHANPGG--TVTWSKNGMIV-------QNHWR---RVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTH 1487
+ V + ++N NL+V+ L L L L L N I + P A+ +L L LS N + + SS + L L L + N + F+ D F+ L L+ L+L + IE NG + GL LQ LDL+ N + LK +Q E L + CDC+L+WL W T + L C P L R++F ++G +L C P+I Q K +N+TF C ++ T W K+ ++ Q H R RV ++ ++ + L L+ V+ + G ++C+++ H
Sbjct: 220 ENVEVLQLDNNNLTVVTKRWLYGLLTLQQLHLGHNAIGAIEPEAWDFCQKLSQLDLSSNHL----TRLEESSFVGLSLLDELHIGNNSISFIADGAFRGLPSLKTLDLKNNEISWTIEDMNGPFSALHNLKRLFLHGNRIRSVTAKSFSGLDALQHLDLSRNAIMAIQVDAFAPLKNLQ--ELRLNTSSLLCDCHLKWLPVWVTEQ-----------------TFLLRLNASCAHPQTLKGRSVF-------AVGQEELVCVDFPKPQITVQPETQSALKGNNVTFLCTAASSSDSPMTFAWKKDNEVLNDAEIHNQAHLRVQGRVG-GETEVTEYTSTLQLRTVDFSSEGKYQCVISNH 548
BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: slit1a (slit guidance ligand 1 [Source:NCBI gene;Acc:101164917]) HSP 1 Score: 82.8037 bits (203), Expect = 1.115e-15 Identity = 59/199 (29.65%), Postives = 92/199 (46.23%), Query Frame = 3
Query: 486 CTNYKANFTRIPERFPDQVAEIIIENQNLSVIDS-AQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKV 1079
C+N K T+IPE P +E+ + N ++ +D+ KNL L + L++NKIT++ F +I L L+ NQI + M F+ L+ LR+L L NK + + GL N+++L L +N TT++ G +L+ L+ L N +NCDC L WL W S K+
Sbjct: 529 CSNLK--LTKIPEHIPSSTSELRLNNNEITSLDANGAFKNLAQLKKINLSNNKITEIEDGTFEGASAVIELHLTANQIDSVRSGM----------------------------FRGLEGLRMLMLRN-NKISCVHNDSFTGLHNVRLLSLYDNQLTTITPGAFDTLQT--LSTLNLLANSFNCDCRLAWLGDWLRSRKI 694 HSP 2 Score: 75.485 bits (184), Expect = 2.304e-13 Identity = 74/296 (25.00%), Postives = 123/296 (41.55%), Query Frame = 3
Query: 432 SVQGCITIMKDSKYKMSICTN-----YKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPK---CESPF----PLSERNI-FSDSTNTDSIGINDLKCAPRIFTQDRVYEMT 1280
S+Q C +I S M C+N T IP PD +AEI +E + + + L + L++N+I++++P+AF + L SL L GN+I DL + + LL +I I N L NL +L L +N TL++G SL+A+Q +L NP+ CDCNL+WL + S+ ++ + + K I ++ K C PL ++ +D+ N+D + C P+ + V + +
Sbjct: 273 SLQPC-SIGGGSCPAMCTCSNNIVDCRGKGLTAIPANLPDNMAEIRLEQNGIKSVPPGAFSSYKKLRRIDLSNNQISEIAPDAFQGLRSLNSLVLYGNKI--------------------TDLPKGVFDGLYALQLLLLNANKI---------HCIRANTFQDLQNLSLLSLYDNKIQTLAKGTFTSLRAIQT--LHLAQNPFICDCNLKWLADYLRSNPIETSGARCASPRRLANKRIGQIKSKKFRCSGSILTFSPLGTEDVRLNDACNSDPV------CPPKCRCESNVVDCS 530 HSP 3 Score: 67.3958 bits (163), Expect = 6.110e-11 Identity = 55/185 (29.73%), Postives = 85/185 (45.95%), Query Frame = 3
Query: 516 IPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLK--KLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWF 1064
+P P + + NL+ I + L + L L N+IT + AF + +L LRL+ NQ+ +P L++ K L LDLSEN + +P F+ ++ L L N IE + L+VL L NN+ +++ +S +L F L +N NCDC+L WL W
Sbjct: 57 MPRNIPRNTERLELNGNNLTRITKSDFTGLKYVRVLQLMENQITVVERGAFDDMKELERLRLNRNQL----QQLP--ELLFQKNPALSRLDLSENFIQSIPRKAFRGATDIKNLQLDK-NHISCIEDGAFRAMRGLEVLTLNNNNISSIP--VSSFNHMPKLRTFRLHSNNLNCDCHLAWLAQWL 232
BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: slit1a (slit guidance ligand 1 [Source:NCBI gene;Acc:101164917]) HSP 1 Score: 82.8037 bits (203), Expect = 1.183e-15 Identity = 59/199 (29.65%), Postives = 92/199 (46.23%), Query Frame = 3
Query: 486 CTNYKANFTRIPERFPDQVAEIIIENQNLSVIDS-AQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKV 1079
C+N K T+IPE P +E+ + N ++ +D+ KNL L + L++NKIT++ F +I L L+ NQI + M F+ L+ LR+L L NK + + GL N+++L L +N TT++ G +L+ L+ L N +NCDC L WL W S K+
Sbjct: 528 CSNLK--LTKIPEHIPSSTSELRLNNNEITSLDANGAFKNLAQLKKINLSNNKITEIEDGTFEGASAVIELHLTANQIDSVRSGM----------------------------FRGLEGLRMLMLRN-NKISCVHNDSFTGLHNVRLLSLYDNQLTTITPGAFDTLQT--LSTLNLLANSFNCDCRLAWLGDWLRSRKI 693 HSP 2 Score: 75.8702 bits (185), Expect = 1.558e-13 Identity = 74/295 (25.08%), Postives = 123/295 (41.69%), Query Frame = 3
Query: 432 SVQGCITIMKDSKYKMSICTN-----YKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPK---CESP----FPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMT 1280
S+Q C +I S M C+N T IP PD +AEI +E + + + L + L++N+I++++P+AF + L SL L GN+I DL + + LL +I I N L NL +L L +N TL++G SL+A+Q +L NP+ CDCNL+WL + S+ ++ + + K I ++ K C + P +E +D+ N+D + C P+ + V + +
Sbjct: 273 SLQPC-SIGGGSCPAMCTCSNNIVDCRGKGLTAIPANLPDNMAEIRLEQNGIKSVPPGAFSSYKKLRRIDLSNNQISEIAPDAFQGLRSLNSLVLYGNKI--------------------TDLPKGVFDGLYALQLLLLNANKI---------HCIRANTFQDLQNLSLLSLYDNKIQTLAKGTFTSLRAIQT--LHLAQNPFICDCNLKWLADYLRSNPIETSGARCASPRRLANKRIGQIKSKKFRCSAKEQYVIPGTEDVRLNDACNSDPV------CPPKCRCESNVVDCS 529 HSP 3 Score: 67.3958 bits (163), Expect = 6.428e-11 Identity = 55/185 (29.73%), Postives = 85/185 (45.95%), Query Frame = 3
Query: 516 IPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLK--KLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWF 1064
+P P + + NL+ I + L + L L N+IT + AF + +L LRL+ NQ+ +P L++ K L LDLSEN + +P F+ ++ L L N IE + L+VL L NN+ +++ +S +L F L +N NCDC+L WL W
Sbjct: 57 MPRNIPRNTERLELNGNNLTRITKSDFTGLKYVRVLQLMENQITVVERGAFDDMKELERLRLNRNQL----QQLP--ELLFQKNPALSRLDLSENFIQSIPRKAFRGATDIKNLQLDK-NHISCIEDGAFRAMRGLEVLTLNNNNISSIP--VSSFNHMPKLRTFRLHSNNLNCDCHLAWLAQWL 232
BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: nyx (nyctalopin [Source:NCBI gene;Acc:101167659]) HSP 1 Score: 81.2629 bits (199), Expect = 1.303e-15 Identity = 87/308 (28.25%), Postives = 138/308 (44.81%), Query Frame = 3
Query: 210 KVSVKRISERHFKLFKSFQIL---K*NFVFF----------LEILKKNHRVTIDFIF---FTMIRETKFICLQDLFLWIFIVLDQVQFGLSVQGCITIMKDSKYKMSICTNYKANFTRIPE--RFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKV 1079
K S+K +SER F S ++L N F L LK H I ++ FT +++ + + D L F + D++ ++ + K +C ++ NF RIP R + + I +E + + L L +L L L N+I + NAF + +L + L+ N + + +P S+ L +L L+L N L V + L +L +L L N+ IE LT+L L L +N+ TTL S+ L YLF NPW CDC+L+WLK W ++K+
Sbjct: 66 KNSLKFLSERAFGTLPSLKMLTLDHNNISFITPGAFKGLSNLVELKMAHNEYISYLHTRTFTGLKKLLRLDVSDCNL--FSIPDRI-----------FLEQTALKELLC--FQNNFRRIPGALRGMENLTHIYLERNKIEAVAYNSLLGLGSLKYLNLQENRINVIHDNAFQDLIRLENFYLNDNLL----SDLPRSAFRGLSRLKMLNLGGNQLINVSKTWLSDLVELEVLYLDR-NQLQNIEEGTFENLTSLITLHLNSNNLTTLP--FSVFQPIYFLGHLYLFRNPWECDCSLEWLKDWMENYKL 351 HSP 2 Score: 58.151 bits (139), Expect = 2.288e-8 Identity = 48/172 (27.91%), Postives = 82/172 (47.67%), Query Frame = 3
Query: 498 KANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSE----GLSISLKAMQLNE 1001
++ +P+ FP + + I +E +L + LP+L LTL+ N I+ ++P AF + L+ L+++ N+ + + + + LKKL LD+S+ L +PD F L+Q + L F L G+ NL + L N ++ GL SLK + L E
Sbjct: 45 RSGLAELPKEFPCEASAINLEKNSLKFLSERAFGTLPSLKMLTLDHNNISFITPGAFKGLSNLVELKMAHNEYI---SYLHTRTFTGLKKLLRLDVSDCNLFSIPDRIF--LEQTALKELLCFQNNFRRIPGALRGMENLTHIYLERNKIEAVAYNSLLGLG-SLKYLNLQE 210
BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: lingo4b (leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 [Source:NCBI gene;Acc:101164675]) HSP 1 Score: 79.337 bits (194), Expect = 7.907e-15 Identity = 84/332 (25.30%), Postives = 144/332 (43.37%), Query Frame = 3
Query: 546 EIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRL----------SGNQIYLGENSM----------PSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNIT--FTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCI 1475
E+ ++ NL+ I + L L +L + + I+ L NAF +P+L +L++ S + I L S+ P ++L +L L LDLS NP+ + L +L+ L+L+ A+ IE GL+ ++L++T+N TTL E S+ +Q+ L NP CDC L W+ ++ + L+ D QP C SP + +R F D + + + + C P R E + T F+C+ +P T+TW + +H VS + L ++ + DSG ++C+
Sbjct: 181 ELNLDRSNLTSIPTEALTQLQSLTVIRMFRLTISSLPNNAFRRLPRLRTLQILNWPALDTIASNSLIGLNLTSLTISSCNLTAVPYAALRHLVYLRFLDLSYNPITVIQGNLLGDLLRLQELHLAGASL-LRIEPGAFKGLSFFRMLNVTSNMLTTLEESAFHSVGNLQV--LRLDGNPLACDCRLLWV--------MRRRQRLNFD----------GHQPTCSSPDAVQQRE-FRDFSEKELVRL--FTCRPARIMDRRPQEARVEEGTTVLFSCKADGDPFPTITW------ISSHKNTVSPTGRIRVLPNGTLEVRFAQVQDSGTYQCL 482 HSP 2 Score: 58.9214 bits (141), Expect = 1.961e-8 Identity = 49/191 (25.65%), Postives = 87/191 (45.55%), Query Frame = 3
Query: 405 VLDQVQFGLSVQGCITIMK-DSKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTL-SEGLS 971
+L Q G+S C + + + IC+ N +PE F + + + + + Q L L +L L+ N I+ + AF + L +LR+ N++ + +P L L LDLS+N + DY F+ + L+ L + N +I +GL NLQ L+L ++ T++ +E L+
Sbjct: 15 ILLQFGLGVSAGSCPSRCACRPEVREVICSGKYLN--SVPEGFSNDARRLDLSRNKIKTVGRRQFSGLVQLQDLDLSDNLISMIEVEAFLGLKNLKTLRIKNNRLKI----LPVGVFSGLYSLRLLDLSQNEILVFLDYTFKEVANLQTLE-AGENDLVFISQRAFFGLQNLQELNLDRSNLTSIPTEALT 198
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000006317.1 (SMESG000006317.1) HSP 1 Score: 1234.17 bits (3192), Expect = 0.000e+0 Identity = 636/640 (99.38%), Postives = 638/640 (99.69%), Query Frame = 3
Query: 348 MIRETKFICLQDLFLWIFIVLDQVQFGLSVQGCITIMKDSKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKVISPQNIIDFKSILKYXXXXXXXXXXXXXXXXXXXYCVYGFQIQNNRRPKKSLSAILIEEKETPVKQNLGNYHIISKSCKEIDYNNKIIVSPIDDAQYYTSQLIESNHTFIQPCLEQPHSPFSHYLVNGSSTICPLHGELXXXXXXXXXXXXNNIEKKLPIQIPIPDSNTVPSSSIPCPIHGDVLSYLSCPVSTNAPPLSSTAIGKPNKEYVLRVTTSNPNTAITSNSLSMDFKYLSSGPQGTSFSTAI 2267
MIRETKFICLQDLFLWIFIVLDQVQFGLSVQGCITIMKDSKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITIN GKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKVISPQNIIDFKSILKYVGIGAVTLILLLVVIGIIIYCVYGFQIQNNRRPKKSLSAILIEEKETPVKQNLGNYHIISK CKEIDYN+KIIVSPIDDAQYYTSQLIESNHTFIQPCLEQPHSPFSHYLVNGSSTICPLHGELSKQKSQKFDDSSNNIEKKLPIQIP+PDSNTVPSSSIPCPIHGDVLSYLSCPVSTNAPPLSSTAIGKPNKEYVLRVTTSNPNTAITSNSLSMDFKYLSSGPQGTSFSTAI
Sbjct: 1 MIRETKFICLQDLFLWIFIVLDQVQFGLSVQGCITIMKDSKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINGGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKVISPQNIIDFKSILKYVGIGAVTLILLLVVIGIIIYCVYGFQIQNNRRPKKSLSAILIEEKETPVKQNLGNYHIISKPCKEIDYNSKIIVSPIDDAQYYTSQLIESNHTFIQPCLEQPHSPFSHYLVNGSSTICPLHGELSKQKSQKFDDSSNNIEKKLPIQIPLPDSNTVPSSSIPCPIHGDVLSYLSCPVSTNAPPLSSTAIGKPNKEYVLRVTTSNPNTAITSNSLSMDFKYLSSGPQGTSFSTAI 640
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000058478.1 (SMESG000058478.1) HSP 1 Score: 358.607 bits (919), Expect = 1.286e-111 Identity = 234/593 (39.46%), Postives = 330/593 (55.65%), Query Frame = 3
Query: 420 QFGLSVQGCITIMKDSKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHK-VKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKV---ISPQNIIDFKSILKYXXXXXXXXXXXXXXXXXXXYCVYGFQIQNNRRPKKSLSAILIEEKET--PVKQNLGNYHIISKSCKEIDYNNKIIVSPIDDAQYYTSQLIESNHTFIQPCLEQPHSPF------SHYLVNGSSTI-CPLHGELX--XXXXXXXXXXXNNIEKKLPIQIPIP-----------------------DSNTVPSSSIPCPIHGDVLSYL 2084
++ SV GC+TIM K K IC+ + FTRIP PD V + ++NQN+ + + QL + L +L L+SNK++ + +AF +VP+L +L L N + LG NS PS++L+ LK L LDL NPLGFVPD++FQ LK L L LS A GFY+E N L GLT+L+ LD++ +H T L + +L MQL +FY F N W CDCNL+WLK W HK V+ K S+ S LQP+C SP NIF ST D+I L C P+IFT+++ ++ + N+T CEF A+PGGTV WSKNGM VQ HW++ W ++ G++F AWL++ + D+G WRCIL T NAT+ L+V P ID ILKY+GIGA+TLILLLV+IGI IYCVYGF+I+ + K +A + + P + + N+H S S + + N + D Q + N+ Q CL P SP + ++N S+ I CPLHG ++ + +N+E PI P ++ T P+S I CP+HG++L+ +
Sbjct: 22 KYSESVVGCVTIMIAEKRKQCICSRLETKFTRIPHDLPDFVETLEVKNQNIHSLTADQLVKVGWLEDLNLDSNKLSSIEFDAFNNVPKLKTLSLKSNFLILGGNSFPSAALLQLKHLKVLDLDNNPLGFVPDFFFQPLKFLTKLILSRATNGFYLEPNSLVGLTSLEYLDISASHLTALDRQIHSALNNMQLTDFYFFGNQWTCDCNLKWLKKWGLKHKDVRIFKKFSR-----SNGQSALLQPQCFSPHKFQGYNIFEFSTEYDTIKPEQLNCPPKIFTKNQQIQIDQGKNLTLMCEFEADPGGTVEWSKNGMRVQRHWKKTKWGQTSGMRFTAWLSITRTDLEDNGLWRCILITDTQSANATYSLRVRPSFPPH--IDLTIILKYIGIGAITLILLLVIIGIAIYCVYGFRIRPFIKQGKGSTASHSQPDRSIRPTRLDGENHHCESNSIRPLTVN---ALVNKDKRQTEENLKKYCNNDESQKCLLLPSSPALVIPITNQTVINNSTHIPCPLHGNINFIDHSAFTDSKQHSNMEYNNPIGFIQPHTLPRQNNRTMNRMKTNPIFITSNNQTNPNSCISCPLHGNILASI 604
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000006503.1 (SMESG000006503.1) HSP 1 Score: 172.555 bits (436), Expect = 6.132e-45 Identity = 120/386 (31.09%), Postives = 201/386 (52.07%), Query Frame = 3
Query: 537 QVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTS--HKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEEN-DSGNWRCILTTHV--SKVNATFLLKVISPQ-NIIDFKS--ILKYXXXXXXXXXXXXXXXXXXXYCVYGFQIQNNRRPK 1670
+A + + N+ ++ L + NL+NLTL+SNKI K++ NAF + +L L L N + + N+ SS YL +L LDLS NP+G +P+ +F L+ LR L L K I+ L NL++L L N+F +L L + MQL L +NPW CDC ++W K W + Y ++I +N ++ CE+P L + + + ++ +C P+ + + N+T +C+F + P V W KNG+++Q+HW R+ ++S G + A LT+ + + D G + C T +V ++ N T ++K+ S + N ID+K I+ + I A +I L++++GI+IYC YG + N + K
Sbjct: 47 DIAILDLSKNNIRILYEDALDDFENLINLTLDSNKIWKITNNAFKNKSKLKYLSLRNNALIISNNTFLSSVFRYLIRLEYLDLSSNPIGIIPESFFLDLRNLRELYLEEMMKEIRIQKGAFSNLFNLKLLSLAKNNFLSLPNYLEYEFQEMQLETLLLHDNPWACDCRMRWFKRWLITLNQNNDYLYSTIENILLNIHPML------CETPDYLQRKKLC-------DLPLSKFECKPKTLRLGKTLVVKHLENVTLSCQFESFPKSYVKWFKNGILIQDHWDRIQLSQSSGRNYVANLTIFSSKYGIDDGCYVCETTNNVGSARSNYTLIIKIPSHKDNAIDYKKQQIILLLIIVASGIITLIILVGIVIYCFYGNSLTNENKFK 419
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000023338.1 (SMESG000023338.1) HSP 1 Score: 150.214 bits (378), Expect = 4.087e-37 Identity = 110/386 (28.50%), Postives = 190/386 (49.22%), Query Frame = 3
Query: 426 GLSVQGCITIMKD--SKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGENSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLLKQLRILNLSTAN-KGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGLSISLKAMQ-LNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPFPLSERNIFSDSTNTDSIGIN---DLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGTVTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRCILTTHVSKVNATFLLKVISPQNIIDFKSIL 1562
++++GC+ + + S + +C + K+ IP PD +II QN+ VI KN+ L L+L + + ++ NAF ++ L L LSGN++ L ++S+PS + L L L L+ NPL +PD++F+ L LR L L+ I + +GL +L+ LDL N+ T+++ + + M+ L L NPW CDC+L+WL +Y ++ + IT+ ++ + P+C+ P L I + S + +KC+ R+ + V + K N+ TC+ ++P V W+KNG V+ + S F + L +++++ DSG+W C V V F LK I+P +I + L
Sbjct: 21 AVAIKGCVVTLVNPTSLKRRVLCGDPKSQIELIPNPLPDATEMLIITQQNIPVIKEEDFKNVLELSTLSLTFSNLERIHRNAFKNLSYLTILDLSGNKLILNDDSLPSYLITNLVNLKHLKLTNNPLKMIPDFFFKPLSSLRKLLLNDCGFDSLRISSRAFHGLNSLEELDLRNSGIETINKTMESDFREMKPLRVLLLGENPWICDCHLRWL--------YRYLGEIQEFITL---QLDNKVGPRCKQPKRLENYRIIAGIDRNQSKYVEFVCPIKCS-RVSPGNVVLDSEKSLNL--TCKCFSDPIKPVIWTKNGYKVEETVNKFQIFNSGNENFYSTLHIRSLKSVDSGSWSC----RVDDVFQNFTLK-INPNSIFPMAASL 387
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000075643.1 (SMESG000075643.1) HSP 1 Score: 134.806 bits (338), Expect = 1.342e-32 Identity = 101/376 (26.86%), Postives = 180/376 (47.87%), Query Frame = 3
Query: 384 LFLWIFIVLDQVQFGLSVQGCITIMKD--SKYKMSICTNYKANFTRIPERFPDQVAEIIIENQNLSVIDSAQLKNLPNLVNLTLNSNKITKLSPNAFTHVPQLISLRLSGNQIYLGE-NSMPSSSLIYLKKLHTLDLSENPLGFVPDYYFQLL-KQLRILNLSTANKGFYIETNGLYGLTNLQVLDLTNNHFTTLSEGL-SISLKAMQLNEFYLFNNPWNCDCNLQWLKAWFTSHKVKYTKDLSKDITINSGKIIEDLQPKCESPF-------PLSERNIFSDSTNTDSIGINDLKCAPRIFTQDRVYEMTKDHNITFTCEFHANPGGT-VTWSKNGMIVQNHWRRVSWNRSQGIKFKAWLTLQNVEENDSGNWRC 1472
+ ++IF+ Q +V+GC ++K S +K++IC + N RIP+ + + + QNL+ +++ + ++ L LTLNS + +S AF H+ QL+ L LS N + + + N++ S L L LDLS N + +P ++F+ L K L++L +S + F I + L L L+ LD+++N+ L G S+ K + L L NPW CDC ++WL W+ + G + P S F P S N + + I ++ C P+ +++ + + + N++ C F + T + WS NG +++++ R +S + ++ LTL + SG WRC
Sbjct: 11 VLVYIFVTFSIPQSD-AVRGCTVMLKSDQSNFKVAICNDPSTNLERIPKDLSVNLIRLEMMYQNLTSLEANEFSHIYQLELLTLNSCGVRHISTTAFEHLSQLVILTLSNNSLVIHDINNLQSEIFQPLIGLTLLDLSFNFIQMIPKHFFRYLEKSLKVLIISNSKSPFSISPDSLSDLVRLERLDISHNNLIQLDSGFESVFSKMISLQNLILHGNPWKCDCKIRWLVFWYQHSTL--------------GSFPAESSPSSLSHFQSALCHSPRSMHNAILLRSISIPIKSHEFPCFPKCLSKNSDFFVGEGENVSLPCSFQSLDQYTRIKWSHNGTLLKSNSRNYVI-KSDTKRHRSVLTLIHFTIKLSGLWRC 370 The following BLAST results are available for this feature:
BLAST of Ig-like domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Ig-like domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002350 ID=SMED30002350|Name=Ig-like domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2607bpback to top protein sequence of SMED30002350-orf-1 >SMED30002350-orf-1 ID=SMED30002350-orf-1|Name=SMED30002350-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=641bp MIRETKFICLQDLFLWIFIVLDQVQFGLSVQGCITIMKDSKYKMSICTNYback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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